ORF_ID e_value Gene_name EC_number CAZy COGs Description
NHPEKHJJ_00001 9.2e-86 D CobQ CobB MinD ParA nucleotide binding domain protein
NHPEKHJJ_00003 2.6e-177 sthIM 2.1.1.72 L DNA methylase
NHPEKHJJ_00004 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
NHPEKHJJ_00005 2.1e-13
NHPEKHJJ_00007 2.3e-35 L Resolvase, N terminal domain
NHPEKHJJ_00011 1.5e-145
NHPEKHJJ_00012 1.3e-260 S Putative peptidoglycan binding domain
NHPEKHJJ_00014 5.9e-30 2.7.13.3 T GHKL domain
NHPEKHJJ_00015 2e-180 yfeX P Peroxidase
NHPEKHJJ_00016 2.9e-71 arcD S C4-dicarboxylate anaerobic carrier
NHPEKHJJ_00017 1e-182 arcD S C4-dicarboxylate anaerobic carrier
NHPEKHJJ_00018 4.1e-253 ytjP 3.5.1.18 E Dipeptidase
NHPEKHJJ_00019 5.3e-215 uhpT EGP Major facilitator Superfamily
NHPEKHJJ_00020 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NHPEKHJJ_00021 4.8e-132 ponA V Beta-lactamase enzyme family
NHPEKHJJ_00023 1.5e-72 M PFAM NLP P60 protein
NHPEKHJJ_00024 2.2e-182 ABC-SBP S ABC transporter
NHPEKHJJ_00025 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NHPEKHJJ_00026 1.1e-136 XK27_08845 S ABC transporter, ATP-binding protein
NHPEKHJJ_00027 1e-91 P Cadmium resistance transporter
NHPEKHJJ_00028 1.2e-55 K Transcriptional regulator, ArsR family
NHPEKHJJ_00029 3.9e-93 M domain protein
NHPEKHJJ_00030 1.6e-236 mepA V MATE efflux family protein
NHPEKHJJ_00031 2.1e-54 trxA O Belongs to the thioredoxin family
NHPEKHJJ_00032 1.5e-130 terC P membrane
NHPEKHJJ_00033 4.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHPEKHJJ_00034 1.5e-166 corA P CorA-like Mg2+ transporter protein
NHPEKHJJ_00035 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
NHPEKHJJ_00036 1.5e-172 malR K Transcriptional regulator, LacI family
NHPEKHJJ_00037 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NHPEKHJJ_00038 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NHPEKHJJ_00039 6.1e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHPEKHJJ_00040 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
NHPEKHJJ_00043 0.0 clpL O associated with various cellular activities
NHPEKHJJ_00044 7.8e-32
NHPEKHJJ_00045 6.1e-216 patA 2.6.1.1 E Aminotransferase
NHPEKHJJ_00046 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPEKHJJ_00047 5e-75 osmC O OsmC-like protein
NHPEKHJJ_00049 5.8e-64
NHPEKHJJ_00050 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHPEKHJJ_00051 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHPEKHJJ_00052 0.0 dnaK O Heat shock 70 kDa protein
NHPEKHJJ_00053 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHPEKHJJ_00054 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHPEKHJJ_00055 4.1e-275 pipD E Dipeptidase
NHPEKHJJ_00056 4.7e-199 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NHPEKHJJ_00058 2.5e-280 pipD E Dipeptidase
NHPEKHJJ_00059 3.6e-241 pbuX F xanthine permease
NHPEKHJJ_00060 1.8e-251 nhaC C Na H antiporter NhaC
NHPEKHJJ_00061 1.8e-240 S C4-dicarboxylate anaerobic carrier
NHPEKHJJ_00062 1.1e-27 S C4-dicarboxylate anaerobic carrier
NHPEKHJJ_00063 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
NHPEKHJJ_00064 1.3e-41
NHPEKHJJ_00065 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHPEKHJJ_00066 1.7e-207 gldA 1.1.1.6 C dehydrogenase
NHPEKHJJ_00067 5.5e-126 S Alpha beta hydrolase
NHPEKHJJ_00068 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHPEKHJJ_00069 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHPEKHJJ_00070 4.7e-300 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHPEKHJJ_00071 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHPEKHJJ_00072 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHPEKHJJ_00073 9.7e-39 S Protein of unknown function (DUF2508)
NHPEKHJJ_00074 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHPEKHJJ_00075 7.6e-52 yaaQ S Cyclic-di-AMP receptor
NHPEKHJJ_00076 2.8e-185 holB 2.7.7.7 L DNA polymerase III
NHPEKHJJ_00077 5.9e-58 yabA L Involved in initiation control of chromosome replication
NHPEKHJJ_00078 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHPEKHJJ_00079 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
NHPEKHJJ_00080 8.5e-279 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NHPEKHJJ_00081 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NHPEKHJJ_00082 1.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NHPEKHJJ_00083 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHPEKHJJ_00084 2.5e-101
NHPEKHJJ_00086 1.4e-124 yciB M ErfK YbiS YcfS YnhG
NHPEKHJJ_00087 1.7e-103 dedA 3.1.3.1 S SNARE associated Golgi protein
NHPEKHJJ_00088 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPEKHJJ_00089 1.5e-80 K AsnC family
NHPEKHJJ_00090 1.5e-80 uspA T universal stress protein
NHPEKHJJ_00091 1.9e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
NHPEKHJJ_00092 0.0 lacS G Transporter
NHPEKHJJ_00093 9.7e-112 L Transposase
NHPEKHJJ_00094 9.8e-09 K DNA-binding helix-turn-helix protein
NHPEKHJJ_00095 8.2e-50 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHPEKHJJ_00096 2.4e-265 glnPH2 P ABC transporter permease
NHPEKHJJ_00097 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NHPEKHJJ_00098 3.8e-70 yqeY S YqeY-like protein
NHPEKHJJ_00099 4.4e-17
NHPEKHJJ_00102 0.0 L helicase activity
NHPEKHJJ_00103 3.3e-207 K DNA binding
NHPEKHJJ_00104 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
NHPEKHJJ_00105 2.9e-24 mod 2.1.1.72, 3.1.21.5 L DNA methylase
NHPEKHJJ_00106 4.7e-201 mod 2.1.1.72, 3.1.21.5 L DNA methylase
NHPEKHJJ_00107 5.8e-36 K Cro/C1-type HTH DNA-binding domain
NHPEKHJJ_00108 4e-129
NHPEKHJJ_00109 2.7e-95 S PFAM Archaeal ATPase
NHPEKHJJ_00110 1.3e-46
NHPEKHJJ_00112 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHPEKHJJ_00113 7.9e-158 amtB P ammonium transporter
NHPEKHJJ_00114 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NHPEKHJJ_00115 1.4e-90 S B3 4 domain
NHPEKHJJ_00116 3.3e-92
NHPEKHJJ_00117 6.3e-122 pnb C nitroreductase
NHPEKHJJ_00118 2.9e-73 ogt 2.1.1.63 L Methyltransferase
NHPEKHJJ_00119 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
NHPEKHJJ_00120 9.8e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NHPEKHJJ_00121 7.3e-69 S Protein of unknown function (DUF3021)
NHPEKHJJ_00122 5.4e-77 K LytTr DNA-binding domain
NHPEKHJJ_00123 9.1e-92 K Acetyltransferase (GNAT) family
NHPEKHJJ_00124 3.1e-21
NHPEKHJJ_00125 4.6e-118 ybhL S Belongs to the BI1 family
NHPEKHJJ_00126 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NHPEKHJJ_00127 9.3e-197 S Protein of unknown function (DUF3114)
NHPEKHJJ_00128 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NHPEKHJJ_00129 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NHPEKHJJ_00130 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NHPEKHJJ_00131 9.1e-62 S Domain of unknown function (DUF4828)
NHPEKHJJ_00132 4.5e-191 mocA S Oxidoreductase
NHPEKHJJ_00133 2.6e-228 yfmL L DEAD DEAH box helicase
NHPEKHJJ_00135 7.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHPEKHJJ_00136 9.3e-56
NHPEKHJJ_00139 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
NHPEKHJJ_00140 0.0 helD 3.6.4.12 L DNA helicase
NHPEKHJJ_00141 3.1e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHPEKHJJ_00143 3.1e-256 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHPEKHJJ_00144 1.8e-265 yfnA E amino acid
NHPEKHJJ_00145 8.4e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHPEKHJJ_00146 1.9e-43 1.3.5.4 S FMN binding
NHPEKHJJ_00147 1.3e-221 norA EGP Major facilitator Superfamily
NHPEKHJJ_00148 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NHPEKHJJ_00149 2.6e-42 S Sugar efflux transporter for intercellular exchange
NHPEKHJJ_00150 4e-156 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NHPEKHJJ_00151 3.6e-121 scrR3 K Transcriptional regulator, LacI family
NHPEKHJJ_00152 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
NHPEKHJJ_00153 4.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHPEKHJJ_00154 3.1e-103 metI P ABC transporter permease
NHPEKHJJ_00155 5.7e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NHPEKHJJ_00156 1.2e-252 clcA P chloride
NHPEKHJJ_00157 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NHPEKHJJ_00158 4.5e-104 proW P ABC transporter, permease protein
NHPEKHJJ_00159 6.7e-139 proV E ABC transporter, ATP-binding protein
NHPEKHJJ_00160 6.3e-109 proWZ P ABC transporter permease
NHPEKHJJ_00161 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
NHPEKHJJ_00162 9e-75 K Transcriptional regulator
NHPEKHJJ_00163 4.8e-154 1.6.5.2 GM NAD(P)H-binding
NHPEKHJJ_00165 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
NHPEKHJJ_00166 0.0 cadA P P-type ATPase
NHPEKHJJ_00167 9.2e-74 L hmm pf00665
NHPEKHJJ_00168 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHPEKHJJ_00169 3e-34
NHPEKHJJ_00170 4.3e-289 mntH P H( )-stimulated, divalent metal cation uptake system
NHPEKHJJ_00171 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NHPEKHJJ_00172 2.6e-86 ygfC K transcriptional regulator (TetR family)
NHPEKHJJ_00173 2.1e-183 hrtB V ABC transporter permease
NHPEKHJJ_00174 2.3e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NHPEKHJJ_00175 0.0 yhcA V ABC transporter, ATP-binding protein
NHPEKHJJ_00176 4.6e-38
NHPEKHJJ_00177 3.5e-49 czrA K Transcriptional regulator, ArsR family
NHPEKHJJ_00178 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHPEKHJJ_00179 5.1e-173 scrR K Transcriptional regulator, LacI family
NHPEKHJJ_00180 3e-24
NHPEKHJJ_00181 8.2e-103
NHPEKHJJ_00182 2.6e-214 yttB EGP Major facilitator Superfamily
NHPEKHJJ_00183 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NHPEKHJJ_00184 2.2e-87
NHPEKHJJ_00185 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NHPEKHJJ_00186 2.5e-261 S Putative peptidoglycan binding domain
NHPEKHJJ_00187 9.2e-74 L hmm pf00665
NHPEKHJJ_00188 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHPEKHJJ_00189 1.2e-264 glnP P ABC transporter
NHPEKHJJ_00190 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHPEKHJJ_00192 7.2e-221 cycA E Amino acid permease
NHPEKHJJ_00193 2.3e-218 nupG F Nucleoside transporter
NHPEKHJJ_00194 5.6e-169 rihC 3.2.2.1 F Nucleoside
NHPEKHJJ_00195 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NHPEKHJJ_00196 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NHPEKHJJ_00197 4.3e-151 noc K Belongs to the ParB family
NHPEKHJJ_00198 2.6e-138 soj D Sporulation initiation inhibitor
NHPEKHJJ_00199 1.7e-154 spo0J K Belongs to the ParB family
NHPEKHJJ_00200 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
NHPEKHJJ_00201 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHPEKHJJ_00202 2.2e-134 XK27_01040 S Protein of unknown function (DUF1129)
NHPEKHJJ_00203 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHPEKHJJ_00204 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHPEKHJJ_00205 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NHPEKHJJ_00206 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NHPEKHJJ_00207 2.8e-171 deoR K sugar-binding domain protein
NHPEKHJJ_00208 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHPEKHJJ_00209 1.2e-123 K response regulator
NHPEKHJJ_00210 4.2e-198 hpk31 2.7.13.3 T Histidine kinase
NHPEKHJJ_00211 3.7e-136 azlC E AzlC protein
NHPEKHJJ_00212 1.6e-52 azlD S branched-chain amino acid
NHPEKHJJ_00213 4.5e-48 L PFAM transposase IS200-family protein
NHPEKHJJ_00214 7.4e-134 K LysR substrate binding domain
NHPEKHJJ_00215 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NHPEKHJJ_00216 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHPEKHJJ_00217 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHPEKHJJ_00218 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHPEKHJJ_00219 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHPEKHJJ_00220 6.2e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NHPEKHJJ_00221 6.7e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NHPEKHJJ_00222 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NHPEKHJJ_00223 4.9e-177 K AI-2E family transporter
NHPEKHJJ_00224 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NHPEKHJJ_00225 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NHPEKHJJ_00226 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NHPEKHJJ_00227 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHPEKHJJ_00228 5.2e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHPEKHJJ_00229 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHPEKHJJ_00230 9.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NHPEKHJJ_00231 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPEKHJJ_00232 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPEKHJJ_00233 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPEKHJJ_00234 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHPEKHJJ_00235 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NHPEKHJJ_00236 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHPEKHJJ_00237 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NHPEKHJJ_00238 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
NHPEKHJJ_00239 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHPEKHJJ_00240 7.3e-259 ganB 3.2.1.89 G arabinogalactan
NHPEKHJJ_00241 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHPEKHJJ_00243 3e-14 D nuclear chromosome segregation
NHPEKHJJ_00244 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00245 1.1e-159 L restriction endonuclease
NHPEKHJJ_00246 5.9e-89 mrr L restriction endonuclease
NHPEKHJJ_00247 0.0 L PLD-like domain
NHPEKHJJ_00249 1.2e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NHPEKHJJ_00250 1.6e-69 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
NHPEKHJJ_00251 8.9e-178 L Belongs to the 'phage' integrase family
NHPEKHJJ_00252 4e-92
NHPEKHJJ_00253 5.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHPEKHJJ_00254 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NHPEKHJJ_00255 0.0 yjbQ P TrkA C-terminal domain protein
NHPEKHJJ_00256 7.4e-277 pipD E Dipeptidase
NHPEKHJJ_00257 2.3e-162
NHPEKHJJ_00258 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NHPEKHJJ_00259 2.8e-170 S AI-2E family transporter
NHPEKHJJ_00260 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
NHPEKHJJ_00261 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
NHPEKHJJ_00262 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
NHPEKHJJ_00263 1.8e-87 GM epimerase
NHPEKHJJ_00264 1.7e-154 ypdB V (ABC) transporter
NHPEKHJJ_00265 6.2e-241 yhdP S Transporter associated domain
NHPEKHJJ_00266 9.9e-85 nrdI F Belongs to the NrdI family
NHPEKHJJ_00267 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
NHPEKHJJ_00268 3.1e-193 yeaN P Transporter, major facilitator family protein
NHPEKHJJ_00269 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHPEKHJJ_00270 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHPEKHJJ_00271 5.5e-28
NHPEKHJJ_00274 6.7e-145 clpB O Belongs to the ClpA ClpB family
NHPEKHJJ_00277 1.1e-148 topA2 5.99.1.2 G Topoisomerase IA
NHPEKHJJ_00278 2.1e-51 L Protein of unknown function (DUF3991)
NHPEKHJJ_00279 1e-08 nrdH O Glutaredoxin-like protein NrdH
NHPEKHJJ_00282 7.9e-16 K ORF6N domain
NHPEKHJJ_00283 5.8e-32 XK27_00515 D Glucan-binding protein C
NHPEKHJJ_00284 2.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NHPEKHJJ_00285 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPEKHJJ_00286 3.6e-310 lmrA V ABC transporter, ATP-binding protein
NHPEKHJJ_00287 0.0 yfiC V ABC transporter
NHPEKHJJ_00288 1.1e-283 pipD E Dipeptidase
NHPEKHJJ_00289 3.9e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHPEKHJJ_00290 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
NHPEKHJJ_00291 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NHPEKHJJ_00292 2.7e-244 yagE E amino acid
NHPEKHJJ_00293 4.5e-140 aroD S Serine hydrolase (FSH1)
NHPEKHJJ_00294 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
NHPEKHJJ_00295 5.2e-167 GK ROK family
NHPEKHJJ_00296 0.0 tetP J elongation factor G
NHPEKHJJ_00297 5.1e-81 uspA T universal stress protein
NHPEKHJJ_00298 2.1e-193 lplA 6.3.1.20 H Lipoate-protein ligase
NHPEKHJJ_00299 7.1e-63
NHPEKHJJ_00300 5.2e-14
NHPEKHJJ_00301 1.4e-212 EGP Major facilitator Superfamily
NHPEKHJJ_00302 1.9e-256 G PTS system Galactitol-specific IIC component
NHPEKHJJ_00303 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
NHPEKHJJ_00304 1.1e-161
NHPEKHJJ_00305 1e-72 K Transcriptional regulator
NHPEKHJJ_00306 3.7e-190 D Alpha beta
NHPEKHJJ_00307 2.2e-52 ypaA S Protein of unknown function (DUF1304)
NHPEKHJJ_00308 0.0 yjcE P Sodium proton antiporter
NHPEKHJJ_00309 1.6e-52 yvlA
NHPEKHJJ_00310 1.8e-113 P Cobalt transport protein
NHPEKHJJ_00311 1.6e-247 cbiO1 S ABC transporter, ATP-binding protein
NHPEKHJJ_00312 3e-96 S ABC-type cobalt transport system, permease component
NHPEKHJJ_00313 3.3e-133 S membrane transporter protein
NHPEKHJJ_00314 2.5e-138 IQ KR domain
NHPEKHJJ_00315 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
NHPEKHJJ_00316 2.4e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NHPEKHJJ_00317 1.5e-157 L hmm pf00665
NHPEKHJJ_00318 1.7e-128 L Helix-turn-helix domain
NHPEKHJJ_00319 1.3e-91 L Belongs to the 'phage' integrase family
NHPEKHJJ_00320 6e-37 3.1.21.3 V Type I restriction modification DNA specificity domain
NHPEKHJJ_00321 2.8e-149 V Type I restriction-modification system methyltransferase subunit()
NHPEKHJJ_00323 4e-19 D nuclear chromosome segregation
NHPEKHJJ_00326 3.6e-71
NHPEKHJJ_00329 7.2e-11 T PFAM SpoVT AbrB
NHPEKHJJ_00330 2.7e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHPEKHJJ_00331 5.8e-15 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
NHPEKHJJ_00332 8.4e-18 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NHPEKHJJ_00336 2.3e-66 ruvB 3.6.4.12 L four-way junction helicase activity
NHPEKHJJ_00337 2.2e-48
NHPEKHJJ_00338 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHPEKHJJ_00339 1.6e-105 ypsA S Belongs to the UPF0398 family
NHPEKHJJ_00340 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHPEKHJJ_00341 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NHPEKHJJ_00342 2e-161 EG EamA-like transporter family
NHPEKHJJ_00343 3e-125 dnaD L DnaD domain protein
NHPEKHJJ_00344 2.9e-85 ypmB S Protein conserved in bacteria
NHPEKHJJ_00345 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NHPEKHJJ_00346 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NHPEKHJJ_00347 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NHPEKHJJ_00348 2.1e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NHPEKHJJ_00349 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHPEKHJJ_00350 4.9e-87 S Protein of unknown function (DUF1440)
NHPEKHJJ_00351 0.0 rafA 3.2.1.22 G alpha-galactosidase
NHPEKHJJ_00352 4.2e-189 galR K Periplasmic binding protein-like domain
NHPEKHJJ_00353 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NHPEKHJJ_00354 1.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHPEKHJJ_00355 2.6e-124 lrgB M LrgB-like family
NHPEKHJJ_00356 1.9e-66 lrgA S LrgA family
NHPEKHJJ_00357 2.4e-130 lytT K response regulator receiver
NHPEKHJJ_00358 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NHPEKHJJ_00359 6.8e-148 f42a O Band 7 protein
NHPEKHJJ_00360 1e-259 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NHPEKHJJ_00361 1.3e-156 yitU 3.1.3.104 S hydrolase
NHPEKHJJ_00362 9.2e-39 S Cytochrome B5
NHPEKHJJ_00363 5.4e-113 nreC K PFAM regulatory protein LuxR
NHPEKHJJ_00364 3.6e-160 hipB K Helix-turn-helix
NHPEKHJJ_00365 2.8e-57 yitW S Iron-sulfur cluster assembly protein
NHPEKHJJ_00366 1.6e-271 sufB O assembly protein SufB
NHPEKHJJ_00367 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
NHPEKHJJ_00368 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHPEKHJJ_00369 1.6e-238 sufD O FeS assembly protein SufD
NHPEKHJJ_00370 6.5e-145 sufC O FeS assembly ATPase SufC
NHPEKHJJ_00371 4.2e-32 feoA P FeoA domain
NHPEKHJJ_00372 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NHPEKHJJ_00373 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NHPEKHJJ_00374 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NHPEKHJJ_00375 3.5e-64 ydiI Q Thioesterase superfamily
NHPEKHJJ_00376 7.8e-108 yvrI K sigma factor activity
NHPEKHJJ_00377 5.6e-201 G Transporter, major facilitator family protein
NHPEKHJJ_00378 0.0 S Bacterial membrane protein YfhO
NHPEKHJJ_00379 2.4e-101 T Ion transport 2 domain protein
NHPEKHJJ_00380 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHPEKHJJ_00381 2.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NHPEKHJJ_00382 1.2e-95 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NHPEKHJJ_00383 5.3e-195 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHPEKHJJ_00384 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00385 4e-73 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NHPEKHJJ_00386 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHPEKHJJ_00387 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
NHPEKHJJ_00388 2.4e-223 mdtG EGP Major facilitator Superfamily
NHPEKHJJ_00389 1.2e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHPEKHJJ_00390 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NHPEKHJJ_00391 5.1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHPEKHJJ_00392 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NHPEKHJJ_00393 5.1e-229 lacS G Transporter
NHPEKHJJ_00394 2.1e-107 lacS G Transporter
NHPEKHJJ_00395 8.2e-185 lacR K Transcriptional regulator
NHPEKHJJ_00396 3.6e-68 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHPEKHJJ_00397 5.6e-68 S integral membrane protein
NHPEKHJJ_00398 1.4e-53 M repeat protein
NHPEKHJJ_00399 1.3e-20
NHPEKHJJ_00400 2.5e-163 yueF S AI-2E family transporter
NHPEKHJJ_00401 1.4e-230 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NHPEKHJJ_00402 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHPEKHJJ_00403 8.8e-75 cps3I G Acyltransferase family
NHPEKHJJ_00404 6.7e-37
NHPEKHJJ_00405 1.2e-111 S Psort location CytoplasmicMembrane, score
NHPEKHJJ_00406 1e-37 M Peptidase_C39 like family
NHPEKHJJ_00407 3e-75
NHPEKHJJ_00408 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHPEKHJJ_00409 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHPEKHJJ_00410 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NHPEKHJJ_00411 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
NHPEKHJJ_00412 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHPEKHJJ_00413 6.3e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHPEKHJJ_00414 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHPEKHJJ_00415 3.5e-163 S Tetratricopeptide repeat
NHPEKHJJ_00416 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHPEKHJJ_00417 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHPEKHJJ_00418 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
NHPEKHJJ_00419 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
NHPEKHJJ_00420 0.0 comEC S Competence protein ComEC
NHPEKHJJ_00421 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
NHPEKHJJ_00422 2.6e-80 comEA L Competence protein ComEA
NHPEKHJJ_00423 6.7e-198 ylbL T Belongs to the peptidase S16 family
NHPEKHJJ_00424 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHPEKHJJ_00425 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NHPEKHJJ_00426 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NHPEKHJJ_00427 2e-222 ftsW D Belongs to the SEDS family
NHPEKHJJ_00428 0.0 typA T GTP-binding protein TypA
NHPEKHJJ_00429 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NHPEKHJJ_00430 1.9e-46 yktA S Belongs to the UPF0223 family
NHPEKHJJ_00431 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
NHPEKHJJ_00432 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHPEKHJJ_00433 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NHPEKHJJ_00434 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NHPEKHJJ_00435 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHPEKHJJ_00436 7.4e-68 rmaI K Transcriptional regulator
NHPEKHJJ_00437 1.2e-39
NHPEKHJJ_00438 0.0 ydaO E amino acid
NHPEKHJJ_00439 3.6e-304 ybeC E amino acid
NHPEKHJJ_00440 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
NHPEKHJJ_00441 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHPEKHJJ_00442 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHPEKHJJ_00444 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHPEKHJJ_00445 2.3e-61
NHPEKHJJ_00447 1.3e-70 O Preprotein translocase subunit SecB
NHPEKHJJ_00448 2.9e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NHPEKHJJ_00449 8.5e-249 mmuP E amino acid
NHPEKHJJ_00451 9.2e-297 L Transposase IS66 family
NHPEKHJJ_00452 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
NHPEKHJJ_00454 1.2e-61 T Toxin-antitoxin system, toxin component, MazF family
NHPEKHJJ_00455 5.2e-37
NHPEKHJJ_00457 0.0 snf 2.7.11.1 KL domain protein
NHPEKHJJ_00458 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
NHPEKHJJ_00459 3.8e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHPEKHJJ_00460 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NHPEKHJJ_00461 2e-17 L nuclease
NHPEKHJJ_00462 1.3e-48 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NHPEKHJJ_00463 6.2e-70
NHPEKHJJ_00464 6.7e-104 fic D Fic/DOC family
NHPEKHJJ_00465 1.5e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHPEKHJJ_00466 1.3e-151 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NHPEKHJJ_00467 0.0
NHPEKHJJ_00468 7.2e-88
NHPEKHJJ_00469 1.8e-263
NHPEKHJJ_00470 9.2e-25
NHPEKHJJ_00471 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NHPEKHJJ_00473 1.5e-225 S cog cog1373
NHPEKHJJ_00474 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
NHPEKHJJ_00475 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHPEKHJJ_00476 4.7e-157 EG EamA-like transporter family
NHPEKHJJ_00477 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
NHPEKHJJ_00478 0.0 helD 3.6.4.12 L DNA helicase
NHPEKHJJ_00479 1.2e-115 dedA S SNARE associated Golgi protein
NHPEKHJJ_00480 4.2e-126 3.1.3.73 G phosphoglycerate mutase
NHPEKHJJ_00481 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHPEKHJJ_00482 6.6e-35 S Transglycosylase associated protein
NHPEKHJJ_00484 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPEKHJJ_00485 3.2e-226 V domain protein
NHPEKHJJ_00486 1.6e-94 K Transcriptional regulator (TetR family)
NHPEKHJJ_00487 5.8e-39 pspC KT PspC domain protein
NHPEKHJJ_00488 2.2e-151
NHPEKHJJ_00489 4e-17 3.2.1.14 GH18
NHPEKHJJ_00490 1.5e-82 zur P Belongs to the Fur family
NHPEKHJJ_00491 1.2e-100 gmk2 2.7.4.8 F Guanylate kinase
NHPEKHJJ_00492 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NHPEKHJJ_00493 3e-254 yfnA E Amino Acid
NHPEKHJJ_00494 7.2e-234 EGP Sugar (and other) transporter
NHPEKHJJ_00495 8.1e-230
NHPEKHJJ_00496 4.3e-208 potD P ABC transporter
NHPEKHJJ_00497 4.9e-140 potC P ABC transporter permease
NHPEKHJJ_00498 4.5e-146 potB P ABC transporter permease
NHPEKHJJ_00499 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHPEKHJJ_00500 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHPEKHJJ_00501 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NHPEKHJJ_00502 0.0 pacL 3.6.3.8 P P-type ATPase
NHPEKHJJ_00503 3.4e-85 dps P Belongs to the Dps family
NHPEKHJJ_00504 2.8e-255 yagE E amino acid
NHPEKHJJ_00505 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NHPEKHJJ_00506 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHPEKHJJ_00507 1.7e-128 L Helix-turn-helix domain
NHPEKHJJ_00508 1.5e-157 L hmm pf00665
NHPEKHJJ_00509 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHPEKHJJ_00510 9.7e-173
NHPEKHJJ_00511 5.5e-280 O Arylsulfotransferase (ASST)
NHPEKHJJ_00512 6.1e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NHPEKHJJ_00513 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHPEKHJJ_00514 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHPEKHJJ_00515 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHPEKHJJ_00516 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NHPEKHJJ_00517 4.9e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHPEKHJJ_00518 9.8e-67 yabR J RNA binding
NHPEKHJJ_00519 3.3e-56 divIC D Septum formation initiator
NHPEKHJJ_00520 8.1e-39 yabO J S4 domain protein
NHPEKHJJ_00521 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHPEKHJJ_00522 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHPEKHJJ_00523 4e-113 S (CBS) domain
NHPEKHJJ_00524 1.2e-146 tesE Q hydratase
NHPEKHJJ_00525 4.7e-243 codA 3.5.4.1 F cytosine deaminase
NHPEKHJJ_00526 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
NHPEKHJJ_00527 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
NHPEKHJJ_00528 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHPEKHJJ_00529 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHPEKHJJ_00531 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPEKHJJ_00532 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
NHPEKHJJ_00533 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPEKHJJ_00534 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHPEKHJJ_00535 9e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
NHPEKHJJ_00536 2.2e-136 sprD D Domain of Unknown Function (DUF1542)
NHPEKHJJ_00537 3.1e-126 L PFAM Integrase catalytic region
NHPEKHJJ_00538 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHPEKHJJ_00539 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHPEKHJJ_00540 2.6e-158 htpX O Belongs to the peptidase M48B family
NHPEKHJJ_00541 7e-93 lemA S LemA family
NHPEKHJJ_00542 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHPEKHJJ_00543 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
NHPEKHJJ_00544 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NHPEKHJJ_00545 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHPEKHJJ_00546 2.5e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NHPEKHJJ_00547 1.1e-124 srtA 3.4.22.70 M sortase family
NHPEKHJJ_00548 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
NHPEKHJJ_00549 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHPEKHJJ_00550 4.6e-41 rpmE2 J Ribosomal protein L31
NHPEKHJJ_00551 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHPEKHJJ_00552 0.0 uup S ABC transporter, ATP-binding protein
NHPEKHJJ_00553 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHPEKHJJ_00554 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
NHPEKHJJ_00555 2.3e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NHPEKHJJ_00556 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHPEKHJJ_00557 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHPEKHJJ_00558 3.6e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHPEKHJJ_00559 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHPEKHJJ_00560 3.6e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NHPEKHJJ_00561 7e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NHPEKHJJ_00562 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00567 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NHPEKHJJ_00568 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NHPEKHJJ_00569 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHPEKHJJ_00570 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NHPEKHJJ_00571 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHPEKHJJ_00572 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHPEKHJJ_00573 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHPEKHJJ_00574 1.3e-131 IQ reductase
NHPEKHJJ_00575 3.3e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NHPEKHJJ_00576 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHPEKHJJ_00577 1.9e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHPEKHJJ_00578 4.2e-77 marR K Transcriptional regulator, MarR family
NHPEKHJJ_00579 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHPEKHJJ_00581 1e-201 xerS L Belongs to the 'phage' integrase family
NHPEKHJJ_00582 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00584 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
NHPEKHJJ_00585 5.2e-309 lmrA 3.6.3.44 V ABC transporter
NHPEKHJJ_00587 6.8e-130 K response regulator
NHPEKHJJ_00588 0.0 vicK 2.7.13.3 T Histidine kinase
NHPEKHJJ_00589 2.1e-246 yycH S YycH protein
NHPEKHJJ_00590 2.7e-149 yycI S YycH protein
NHPEKHJJ_00591 4.5e-154 vicX 3.1.26.11 S domain protein
NHPEKHJJ_00592 2.5e-215 htrA 3.4.21.107 O serine protease
NHPEKHJJ_00593 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NHPEKHJJ_00594 1.7e-179 ABC-SBP S ABC transporter
NHPEKHJJ_00595 1.4e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHPEKHJJ_00596 4.4e-100 L Helix-turn-helix domain
NHPEKHJJ_00598 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHPEKHJJ_00599 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHPEKHJJ_00600 9e-119 S Repeat protein
NHPEKHJJ_00601 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NHPEKHJJ_00602 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHPEKHJJ_00603 1.3e-57 XK27_04120 S Putative amino acid metabolism
NHPEKHJJ_00604 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
NHPEKHJJ_00605 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHPEKHJJ_00607 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NHPEKHJJ_00608 4.2e-32 cspA K Cold shock protein
NHPEKHJJ_00609 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHPEKHJJ_00610 1.9e-42 divIVA D DivIVA domain protein
NHPEKHJJ_00611 5.1e-142 ylmH S S4 domain protein
NHPEKHJJ_00612 3.2e-40 yggT S YGGT family
NHPEKHJJ_00613 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHPEKHJJ_00614 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHPEKHJJ_00615 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHPEKHJJ_00616 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHPEKHJJ_00617 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHPEKHJJ_00618 8.5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHPEKHJJ_00619 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHPEKHJJ_00620 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NHPEKHJJ_00621 2.6e-56 ftsL D Cell division protein FtsL
NHPEKHJJ_00622 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHPEKHJJ_00623 3.1e-77 mraZ K Belongs to the MraZ family
NHPEKHJJ_00624 7.3e-56
NHPEKHJJ_00625 1.2e-10 S Protein of unknown function (DUF4044)
NHPEKHJJ_00626 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NHPEKHJJ_00627 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHPEKHJJ_00628 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
NHPEKHJJ_00629 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NHPEKHJJ_00631 8.2e-48
NHPEKHJJ_00632 7.8e-272 S ABC transporter, ATP-binding protein
NHPEKHJJ_00633 2.3e-142 S Putative ABC-transporter type IV
NHPEKHJJ_00634 2e-106 NU mannosyl-glycoprotein
NHPEKHJJ_00635 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
NHPEKHJJ_00636 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
NHPEKHJJ_00637 7.6e-205 nrnB S DHHA1 domain
NHPEKHJJ_00638 6.9e-49
NHPEKHJJ_00639 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHPEKHJJ_00640 5.8e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHPEKHJJ_00641 2e-15 S Domain of unknown function (DUF4767)
NHPEKHJJ_00642 9.5e-55
NHPEKHJJ_00643 5.4e-116 yrkL S Flavodoxin-like fold
NHPEKHJJ_00645 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00646 1.7e-37
NHPEKHJJ_00647 1.2e-105 K DNA-templated transcription, initiation
NHPEKHJJ_00648 4e-28
NHPEKHJJ_00649 9.6e-61 L PFAM transposase IS200-family protein
NHPEKHJJ_00650 2.5e-230 L transposase, IS605 OrfB family
NHPEKHJJ_00651 7.6e-94
NHPEKHJJ_00652 2.2e-69 K Transcriptional regulator, HxlR family
NHPEKHJJ_00653 1.4e-165 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NHPEKHJJ_00654 4.6e-144 epsB M biosynthesis protein
NHPEKHJJ_00655 7.5e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NHPEKHJJ_00656 2e-51 pglC M Bacterial sugar transferase
NHPEKHJJ_00657 4.7e-74 wceM M Glycosyltransferase like family 2
NHPEKHJJ_00658 2.9e-77 glfT1 1.1.1.133 S Glycosyltransferase like family 2
NHPEKHJJ_00659 3e-95 M Glycosyltransferase, group 1 family protein
NHPEKHJJ_00660 3.2e-55 M Domain of unknown function (DUF4422)
NHPEKHJJ_00661 3.9e-30
NHPEKHJJ_00662 2.7e-213 glf 5.4.99.9 M UDP-galactopyranose mutase
NHPEKHJJ_00663 8.1e-60 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NHPEKHJJ_00664 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00665 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00666 3e-50 S CRISPR-associated protein (Cas_Csn2)
NHPEKHJJ_00667 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00668 4e-182 M LPXTG-motif cell wall anchor domain protein
NHPEKHJJ_00669 0.0 M LPXTG-motif cell wall anchor domain protein
NHPEKHJJ_00670 1.1e-19 M LPXTG-motif cell wall anchor domain protein
NHPEKHJJ_00671 4.8e-12 sraP UW domain, Protein
NHPEKHJJ_00674 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00675 1.6e-67 yqkB S Belongs to the HesB IscA family
NHPEKHJJ_00676 2.7e-49
NHPEKHJJ_00678 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NHPEKHJJ_00679 1.3e-61 asp S Asp23 family, cell envelope-related function
NHPEKHJJ_00680 2.1e-25
NHPEKHJJ_00681 3.2e-95
NHPEKHJJ_00682 7e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NHPEKHJJ_00683 9.9e-183 K Transcriptional regulator, LacI family
NHPEKHJJ_00684 1.9e-11 gntT EG Gluconate
NHPEKHJJ_00685 1.2e-201 gntT EG Gluconate
NHPEKHJJ_00686 1.1e-294 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NHPEKHJJ_00687 2.9e-96 K Acetyltransferase (GNAT) domain
NHPEKHJJ_00688 5.4e-47
NHPEKHJJ_00689 2.4e-22
NHPEKHJJ_00690 2.2e-44
NHPEKHJJ_00691 1.8e-57 yhaI S Protein of unknown function (DUF805)
NHPEKHJJ_00692 2.8e-140 IQ reductase
NHPEKHJJ_00693 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NHPEKHJJ_00694 5.3e-282 hsdM 2.1.1.72 V type I restriction-modification system
NHPEKHJJ_00695 1e-135 L Transposase
NHPEKHJJ_00696 1.2e-71 pbuG S permease
NHPEKHJJ_00697 1.1e-150 pbuG S permease
NHPEKHJJ_00698 1.6e-260 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NHPEKHJJ_00699 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NHPEKHJJ_00700 2.5e-135 S Belongs to the UPF0246 family
NHPEKHJJ_00701 2.5e-138 S Membrane
NHPEKHJJ_00702 8.1e-75 4.4.1.5 E Glyoxalase
NHPEKHJJ_00703 1.5e-21
NHPEKHJJ_00704 9.3e-86 yueI S Protein of unknown function (DUF1694)
NHPEKHJJ_00705 1.7e-235 rarA L recombination factor protein RarA
NHPEKHJJ_00706 4.4e-46
NHPEKHJJ_00707 4.3e-83 usp6 T universal stress protein
NHPEKHJJ_00708 5.3e-206 araR K Transcriptional regulator
NHPEKHJJ_00709 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
NHPEKHJJ_00710 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHPEKHJJ_00711 1.3e-266 yjeM E Amino Acid
NHPEKHJJ_00712 4.4e-231 V MatE
NHPEKHJJ_00713 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHPEKHJJ_00714 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHPEKHJJ_00715 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NHPEKHJJ_00716 9.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHPEKHJJ_00717 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHPEKHJJ_00718 2e-58 yodB K Transcriptional regulator, HxlR family
NHPEKHJJ_00719 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHPEKHJJ_00720 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHPEKHJJ_00721 5.6e-115 rlpA M PFAM NLP P60 protein
NHPEKHJJ_00722 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
NHPEKHJJ_00723 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHPEKHJJ_00724 1e-135 L Transposase
NHPEKHJJ_00725 1.9e-225 L Transposase IS66 family
NHPEKHJJ_00727 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHPEKHJJ_00728 2.4e-65 K HxlR-like helix-turn-helix
NHPEKHJJ_00729 8.5e-54 S macrophage migration inhibitory factor
NHPEKHJJ_00730 1.1e-50 yqiG C Oxidoreductase
NHPEKHJJ_00731 7.8e-20 yqiG C Oxidoreductase
NHPEKHJJ_00732 3.7e-91 yqiG C Oxidoreductase
NHPEKHJJ_00734 3.7e-19
NHPEKHJJ_00735 1.9e-262 dtpT U amino acid peptide transporter
NHPEKHJJ_00736 6.9e-15 yjjH S Calcineurin-like phosphoesterase
NHPEKHJJ_00737 1.9e-135 yjjH S Calcineurin-like phosphoesterase
NHPEKHJJ_00740 1.5e-115
NHPEKHJJ_00741 9.1e-251 EGP Major facilitator Superfamily
NHPEKHJJ_00742 9.5e-300 aspT P Predicted Permease Membrane Region
NHPEKHJJ_00743 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NHPEKHJJ_00744 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
NHPEKHJJ_00745 2.9e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHPEKHJJ_00746 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHPEKHJJ_00747 0.0 yhgF K Tex-like protein N-terminal domain protein
NHPEKHJJ_00748 1.9e-85 ydcK S Belongs to the SprT family
NHPEKHJJ_00750 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NHPEKHJJ_00751 1.3e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NHPEKHJJ_00752 0.0 S Bacterial membrane protein, YfhO
NHPEKHJJ_00753 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHPEKHJJ_00754 3.1e-169 I alpha/beta hydrolase fold
NHPEKHJJ_00755 9.4e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NHPEKHJJ_00756 2.4e-119 tcyB E ABC transporter
NHPEKHJJ_00757 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHPEKHJJ_00758 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NHPEKHJJ_00759 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
NHPEKHJJ_00760 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHPEKHJJ_00761 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
NHPEKHJJ_00762 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NHPEKHJJ_00763 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHPEKHJJ_00764 1.7e-207 yacL S domain protein
NHPEKHJJ_00765 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHPEKHJJ_00766 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHPEKHJJ_00767 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHPEKHJJ_00768 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHPEKHJJ_00769 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHPEKHJJ_00770 1.7e-96 nusG K Participates in transcription elongation, termination and antitermination
NHPEKHJJ_00771 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHPEKHJJ_00772 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHPEKHJJ_00773 1.1e-225 aadAT EK Aminotransferase, class I
NHPEKHJJ_00775 2.5e-247 M Glycosyl transferase family group 2
NHPEKHJJ_00776 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHPEKHJJ_00777 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHPEKHJJ_00778 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHPEKHJJ_00779 1.5e-48
NHPEKHJJ_00781 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHPEKHJJ_00782 4e-56 K transcriptional regulator PadR family
NHPEKHJJ_00783 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
NHPEKHJJ_00784 6.4e-126 S Putative adhesin
NHPEKHJJ_00785 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NHPEKHJJ_00786 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPEKHJJ_00787 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPEKHJJ_00788 3.4e-35 nrdH O Glutaredoxin
NHPEKHJJ_00789 1.2e-203 2.7.7.65 T GGDEF domain
NHPEKHJJ_00790 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NHPEKHJJ_00791 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NHPEKHJJ_00792 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
NHPEKHJJ_00793 2e-92 folT S ECF transporter, substrate-specific component
NHPEKHJJ_00794 0.0 pepN 3.4.11.2 E aminopeptidase
NHPEKHJJ_00795 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
NHPEKHJJ_00796 9.8e-255 pepC 3.4.22.40 E aminopeptidase
NHPEKHJJ_00797 6.5e-210 EGP Major facilitator Superfamily
NHPEKHJJ_00798 1.8e-229
NHPEKHJJ_00799 7.8e-79 K Transcriptional regulator, HxlR family
NHPEKHJJ_00800 3.7e-108 XK27_02070 S Nitroreductase family
NHPEKHJJ_00801 2.5e-52 hxlR K Transcriptional regulator, HxlR family
NHPEKHJJ_00802 6.6e-119 GM NmrA-like family
NHPEKHJJ_00803 1.7e-70 elaA S Gnat family
NHPEKHJJ_00804 1.8e-39 S Cytochrome B5
NHPEKHJJ_00805 5.4e-09 S Cytochrome B5
NHPEKHJJ_00806 7.8e-41 S Cytochrome B5
NHPEKHJJ_00807 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
NHPEKHJJ_00809 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHPEKHJJ_00810 1.1e-240 E amino acid
NHPEKHJJ_00811 1.8e-214 npp S type I phosphodiesterase nucleotide pyrophosphatase
NHPEKHJJ_00812 3.1e-226 yxiO S Vacuole effluxer Atg22 like
NHPEKHJJ_00814 4.4e-100 L Helix-turn-helix domain
NHPEKHJJ_00815 1.7e-159 spoU 2.1.1.185 J Methyltransferase
NHPEKHJJ_00816 1.4e-223 oxlT P Major Facilitator Superfamily
NHPEKHJJ_00817 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_00818 9.6e-139 L hmm pf00665
NHPEKHJJ_00819 7.9e-95 L Helix-turn-helix domain
NHPEKHJJ_00820 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHPEKHJJ_00821 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
NHPEKHJJ_00822 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NHPEKHJJ_00823 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NHPEKHJJ_00824 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
NHPEKHJJ_00825 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
NHPEKHJJ_00826 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHPEKHJJ_00827 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
NHPEKHJJ_00828 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NHPEKHJJ_00829 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHPEKHJJ_00830 2.7e-39 ptsH G phosphocarrier protein HPR
NHPEKHJJ_00831 2.9e-27
NHPEKHJJ_00832 0.0 clpE O Belongs to the ClpA ClpB family
NHPEKHJJ_00833 2.4e-99 S Pfam:DUF3816
NHPEKHJJ_00834 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NHPEKHJJ_00835 6.7e-114
NHPEKHJJ_00836 1.8e-153 V ABC transporter, ATP-binding protein
NHPEKHJJ_00837 1e-63 gntR1 K Transcriptional regulator, GntR family
NHPEKHJJ_00838 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHPEKHJJ_00839 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
NHPEKHJJ_00840 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHPEKHJJ_00841 7.4e-141 ymfM S Helix-turn-helix domain
NHPEKHJJ_00842 9.3e-250 ymfH S Peptidase M16
NHPEKHJJ_00843 1.6e-230 ymfF S Peptidase M16 inactive domain protein
NHPEKHJJ_00844 2.6e-160 aatB ET ABC transporter substrate-binding protein
NHPEKHJJ_00845 1.6e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHPEKHJJ_00846 3.2e-102 glnP P ABC transporter permease
NHPEKHJJ_00847 1.2e-91 mreD M rod shape-determining protein MreD
NHPEKHJJ_00848 2.2e-151 mreC M Involved in formation and maintenance of cell shape
NHPEKHJJ_00849 1.7e-179 mreB D cell shape determining protein MreB
NHPEKHJJ_00850 6.8e-121 radC L DNA repair protein
NHPEKHJJ_00851 4.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHPEKHJJ_00852 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
NHPEKHJJ_00853 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NHPEKHJJ_00854 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NHPEKHJJ_00855 1.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NHPEKHJJ_00856 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
NHPEKHJJ_00857 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHPEKHJJ_00858 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHPEKHJJ_00859 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
NHPEKHJJ_00860 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHPEKHJJ_00861 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHPEKHJJ_00862 1.8e-128 L Helix-turn-helix domain
NHPEKHJJ_00863 1.5e-157 L hmm pf00665
NHPEKHJJ_00864 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHPEKHJJ_00865 1.3e-08
NHPEKHJJ_00866 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHPEKHJJ_00867 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHPEKHJJ_00868 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHPEKHJJ_00869 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPEKHJJ_00870 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHPEKHJJ_00871 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHPEKHJJ_00872 2.1e-87
NHPEKHJJ_00873 4.6e-56 sip L Belongs to the 'phage' integrase family
NHPEKHJJ_00874 9.7e-11 K Cro/C1-type HTH DNA-binding domain
NHPEKHJJ_00879 7.3e-46 L Bifunctional DNA primase/polymerase, N-terminal
NHPEKHJJ_00880 1.3e-90 S Phage plasmid primase, P4
NHPEKHJJ_00883 1e-27 L Phage-associated protein
NHPEKHJJ_00884 3.2e-22 terS L Phage terminase, small subunit
NHPEKHJJ_00885 1.5e-202 terL S overlaps another CDS with the same product name
NHPEKHJJ_00886 5.2e-140 S Phage portal protein
NHPEKHJJ_00887 1.2e-248 S Caudovirus prohead serine protease
NHPEKHJJ_00888 1.2e-19 S Phage gp6-like head-tail connector protein
NHPEKHJJ_00889 9.3e-18
NHPEKHJJ_00891 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHPEKHJJ_00892 1.5e-211 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NHPEKHJJ_00893 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHPEKHJJ_00894 1.3e-35 ynzC S UPF0291 protein
NHPEKHJJ_00895 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
NHPEKHJJ_00896 4.6e-117 plsC 2.3.1.51 I Acyltransferase
NHPEKHJJ_00897 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
NHPEKHJJ_00898 5.4e-49 yazA L GIY-YIG catalytic domain protein
NHPEKHJJ_00899 4.4e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPEKHJJ_00900 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
NHPEKHJJ_00901 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHPEKHJJ_00902 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NHPEKHJJ_00903 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHPEKHJJ_00904 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHPEKHJJ_00905 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
NHPEKHJJ_00906 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NHPEKHJJ_00907 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHPEKHJJ_00908 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHPEKHJJ_00909 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NHPEKHJJ_00910 1e-215 nusA K Participates in both transcription termination and antitermination
NHPEKHJJ_00911 1e-44 ylxR K Protein of unknown function (DUF448)
NHPEKHJJ_00912 4.5e-49 ylxQ J ribosomal protein
NHPEKHJJ_00913 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHPEKHJJ_00914 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHPEKHJJ_00915 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHPEKHJJ_00916 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NHPEKHJJ_00917 1.1e-256 malT G Major Facilitator
NHPEKHJJ_00918 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NHPEKHJJ_00919 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NHPEKHJJ_00920 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
NHPEKHJJ_00921 2.1e-117 K response regulator
NHPEKHJJ_00922 5.3e-226 sptS 2.7.13.3 T Histidine kinase
NHPEKHJJ_00923 1.6e-208 yfeO P Voltage gated chloride channel
NHPEKHJJ_00924 8.1e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NHPEKHJJ_00925 6.6e-136 puuD S peptidase C26
NHPEKHJJ_00926 3.8e-167 yvgN C Aldo keto reductase
NHPEKHJJ_00927 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
NHPEKHJJ_00928 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NHPEKHJJ_00929 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
NHPEKHJJ_00930 9.3e-261 nox C NADH oxidase
NHPEKHJJ_00931 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHPEKHJJ_00932 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHPEKHJJ_00933 3e-86
NHPEKHJJ_00934 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHPEKHJJ_00936 4.3e-13 K Transcriptional regulator, TetR family
NHPEKHJJ_00937 6.2e-76 K Transcriptional regulator, TetR family
NHPEKHJJ_00938 1.1e-71
NHPEKHJJ_00939 1.8e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NHPEKHJJ_00940 6.7e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NHPEKHJJ_00941 1.7e-270 M domain protein
NHPEKHJJ_00942 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NHPEKHJJ_00943 2.5e-187 G Major Facilitator
NHPEKHJJ_00944 4.5e-49 G Major Facilitator
NHPEKHJJ_00945 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NHPEKHJJ_00946 1e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHPEKHJJ_00947 4.7e-260 G Major Facilitator
NHPEKHJJ_00948 1.1e-178 K Transcriptional regulator, LacI family
NHPEKHJJ_00949 1.6e-51 K LysR substrate binding domain
NHPEKHJJ_00950 1.2e-189 1.3.5.4 C FAD binding domain
NHPEKHJJ_00951 8.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHPEKHJJ_00953 4.9e-102 nqr 1.5.1.36 S reductase
NHPEKHJJ_00954 1.4e-197 XK27_09615 S reductase
NHPEKHJJ_00955 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHPEKHJJ_00956 1e-135 L Transposase
NHPEKHJJ_00957 8.2e-60 M Peptidase_C39 like family
NHPEKHJJ_00958 1.6e-108 S Peptidase, M23
NHPEKHJJ_00959 2.3e-190 L Transposase
NHPEKHJJ_00960 1.3e-96 2.3.1.128 K Acetyltransferase (GNAT) domain
NHPEKHJJ_00961 8.5e-233 lmrB EGP Major facilitator Superfamily
NHPEKHJJ_00962 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NHPEKHJJ_00963 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHPEKHJJ_00964 4.4e-158 sufD O Uncharacterized protein family (UPF0051)
NHPEKHJJ_00965 1.6e-42 lytE M LysM domain protein
NHPEKHJJ_00966 0.0 oppD EP Psort location Cytoplasmic, score
NHPEKHJJ_00967 2.3e-93 lytE M LysM domain protein
NHPEKHJJ_00968 7.1e-149 xth 3.1.11.2 L exodeoxyribonuclease III
NHPEKHJJ_00969 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NHPEKHJJ_00970 2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
NHPEKHJJ_00971 3.8e-151 yeaE S Aldo keto
NHPEKHJJ_00972 2.9e-75 hsp O Belongs to the small heat shock protein (HSP20) family
NHPEKHJJ_00973 4.2e-278 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NHPEKHJJ_00974 4.5e-79 S Psort location Cytoplasmic, score
NHPEKHJJ_00975 3.8e-85 S Short repeat of unknown function (DUF308)
NHPEKHJJ_00976 1e-23
NHPEKHJJ_00977 7.5e-103 V VanZ like family
NHPEKHJJ_00978 4.5e-231 cycA E Amino acid permease
NHPEKHJJ_00979 4.3e-85 perR P Belongs to the Fur family
NHPEKHJJ_00980 6.9e-254 EGP Major facilitator Superfamily
NHPEKHJJ_00981 9.6e-92 tag 3.2.2.20 L glycosylase
NHPEKHJJ_00982 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHPEKHJJ_00983 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHPEKHJJ_00984 4.9e-41
NHPEKHJJ_00985 4.1e-303 ytgP S Polysaccharide biosynthesis protein
NHPEKHJJ_00986 2.2e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHPEKHJJ_00987 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
NHPEKHJJ_00988 1.2e-85 uspA T Belongs to the universal stress protein A family
NHPEKHJJ_00989 3.2e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHPEKHJJ_00990 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
NHPEKHJJ_00991 3.8e-113
NHPEKHJJ_00992 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NHPEKHJJ_00993 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHPEKHJJ_00994 2.1e-32
NHPEKHJJ_00995 4.5e-112 S CAAX protease self-immunity
NHPEKHJJ_00996 1.9e-43
NHPEKHJJ_00998 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHPEKHJJ_00999 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NHPEKHJJ_01000 1.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NHPEKHJJ_01001 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHPEKHJJ_01002 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NHPEKHJJ_01003 6e-216 folP 2.5.1.15 H dihydropteroate synthase
NHPEKHJJ_01004 1.8e-43
NHPEKHJJ_01005 7.4e-40
NHPEKHJJ_01007 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHPEKHJJ_01008 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NHPEKHJJ_01009 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NHPEKHJJ_01010 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHPEKHJJ_01011 3.5e-40 yheA S Belongs to the UPF0342 family
NHPEKHJJ_01012 1.8e-220 yhaO L Ser Thr phosphatase family protein
NHPEKHJJ_01013 0.0 L AAA domain
NHPEKHJJ_01014 5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHPEKHJJ_01016 1.2e-76 hit FG histidine triad
NHPEKHJJ_01017 1.5e-135 ecsA V ABC transporter, ATP-binding protein
NHPEKHJJ_01018 5.1e-218 ecsB U ABC transporter
NHPEKHJJ_01019 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHPEKHJJ_01020 7.7e-27 S YSIRK type signal peptide
NHPEKHJJ_01021 1.1e-65 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
NHPEKHJJ_01022 3.4e-253 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
NHPEKHJJ_01023 2.3e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NHPEKHJJ_01024 8.6e-81 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NHPEKHJJ_01025 8.8e-184 iolS C Aldo keto reductase
NHPEKHJJ_01026 9.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
NHPEKHJJ_01027 7.5e-58 ytzB S Small secreted protein
NHPEKHJJ_01028 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NHPEKHJJ_01029 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHPEKHJJ_01030 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
NHPEKHJJ_01031 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NHPEKHJJ_01032 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NHPEKHJJ_01033 1.9e-119 ybhL S Belongs to the BI1 family
NHPEKHJJ_01034 4.1e-116 yoaK S Protein of unknown function (DUF1275)
NHPEKHJJ_01035 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHPEKHJJ_01036 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHPEKHJJ_01037 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHPEKHJJ_01038 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHPEKHJJ_01039 1.4e-203 dnaB L replication initiation and membrane attachment
NHPEKHJJ_01040 5.3e-170 dnaI L Primosomal protein DnaI
NHPEKHJJ_01041 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHPEKHJJ_01042 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NHPEKHJJ_01043 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHPEKHJJ_01044 1.8e-95 yqeG S HAD phosphatase, family IIIA
NHPEKHJJ_01045 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
NHPEKHJJ_01046 1.9e-47 yhbY J RNA-binding protein
NHPEKHJJ_01047 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHPEKHJJ_01048 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NHPEKHJJ_01049 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHPEKHJJ_01050 1.7e-139 yqeM Q Methyltransferase
NHPEKHJJ_01051 2.1e-213 ylbM S Belongs to the UPF0348 family
NHPEKHJJ_01052 2.9e-99 yceD S Uncharacterized ACR, COG1399
NHPEKHJJ_01053 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NHPEKHJJ_01054 1.5e-121 K response regulator
NHPEKHJJ_01055 7.7e-277 arlS 2.7.13.3 T Histidine kinase
NHPEKHJJ_01056 2.6e-38 L Transposase
NHPEKHJJ_01064 1.5e-157 L hmm pf00665
NHPEKHJJ_01065 1.8e-128 L Helix-turn-helix domain
NHPEKHJJ_01071 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NHPEKHJJ_01072 1.5e-275 lysP E amino acid
NHPEKHJJ_01073 8.6e-09 2.3.1.128 J Acetyltransferase (GNAT) domain
NHPEKHJJ_01074 2.7e-120 lssY 3.6.1.27 I phosphatase
NHPEKHJJ_01075 6.7e-81 S Threonine/Serine exporter, ThrE
NHPEKHJJ_01076 3.6e-129 thrE S Putative threonine/serine exporter
NHPEKHJJ_01077 3.5e-31 cspC K Cold shock protein
NHPEKHJJ_01078 1.1e-124 sirR K iron dependent repressor
NHPEKHJJ_01079 6.5e-165 czcD P cation diffusion facilitator family transporter
NHPEKHJJ_01080 1.6e-115 S membrane
NHPEKHJJ_01081 8.4e-109 S VIT family
NHPEKHJJ_01082 5.5e-83 usp1 T Belongs to the universal stress protein A family
NHPEKHJJ_01083 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHPEKHJJ_01084 4.8e-151 glnH ET ABC transporter
NHPEKHJJ_01085 4.2e-110 gluC P ABC transporter permease
NHPEKHJJ_01086 1.2e-107 glnP P ABC transporter permease
NHPEKHJJ_01087 7.3e-217 S CAAX protease self-immunity
NHPEKHJJ_01088 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHPEKHJJ_01089 2.9e-57
NHPEKHJJ_01090 2.6e-74 merR K MerR HTH family regulatory protein
NHPEKHJJ_01091 1e-268 lmrB EGP Major facilitator Superfamily
NHPEKHJJ_01092 9.5e-119 S Domain of unknown function (DUF4811)
NHPEKHJJ_01093 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NHPEKHJJ_01095 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHPEKHJJ_01096 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NHPEKHJJ_01097 3.4e-188 I Alpha beta
NHPEKHJJ_01098 8.5e-282 emrY EGP Major facilitator Superfamily
NHPEKHJJ_01099 5e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
NHPEKHJJ_01100 8.8e-251 yjjP S Putative threonine/serine exporter
NHPEKHJJ_01101 1e-159 mleR K LysR family
NHPEKHJJ_01102 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
NHPEKHJJ_01103 1.8e-267 frdC 1.3.5.4 C FAD binding domain
NHPEKHJJ_01104 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHPEKHJJ_01105 1.5e-305 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NHPEKHJJ_01106 1.9e-161 mleR K LysR family
NHPEKHJJ_01107 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHPEKHJJ_01108 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NHPEKHJJ_01109 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
NHPEKHJJ_01110 7.2e-169 L transposase, IS605 OrfB family
NHPEKHJJ_01111 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
NHPEKHJJ_01112 1.5e-25
NHPEKHJJ_01113 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NHPEKHJJ_01114 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHPEKHJJ_01115 1.7e-128 L Helix-turn-helix domain
NHPEKHJJ_01116 1.5e-157 L hmm pf00665
NHPEKHJJ_01117 5.3e-130 S Hydrolases of the alpha beta superfamily
NHPEKHJJ_01118 1.3e-16 S Hydrolases of the alpha beta superfamily
NHPEKHJJ_01119 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
NHPEKHJJ_01120 3.4e-77 ctsR K Belongs to the CtsR family
NHPEKHJJ_01121 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NHPEKHJJ_01122 1e-110 K Bacterial regulatory proteins, tetR family
NHPEKHJJ_01123 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPEKHJJ_01124 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPEKHJJ_01125 1.6e-200 ykiI
NHPEKHJJ_01126 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NHPEKHJJ_01127 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHPEKHJJ_01128 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHPEKHJJ_01129 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHPEKHJJ_01130 8.7e-116 lssY 3.6.1.27 I Acid phosphatase homologues
NHPEKHJJ_01131 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NHPEKHJJ_01132 4.2e-231 clcA_2 P Chloride transporter, ClC family
NHPEKHJJ_01133 7.2e-118 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NHPEKHJJ_01134 4.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NHPEKHJJ_01135 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHPEKHJJ_01136 1.6e-51
NHPEKHJJ_01137 0.0 S SEC-C Motif Domain Protein
NHPEKHJJ_01139 1.8e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NHPEKHJJ_01140 1.2e-129 IQ Dehydrogenase reductase
NHPEKHJJ_01141 2.9e-37
NHPEKHJJ_01142 2.2e-114 ywnB S NAD(P)H-binding
NHPEKHJJ_01143 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
NHPEKHJJ_01144 2e-74 nhaC C Na H antiporter NhaC
NHPEKHJJ_01145 3.5e-149 nhaC C Na H antiporter NhaC
NHPEKHJJ_01146 7.7e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHPEKHJJ_01148 7.9e-102 ydeN S Serine hydrolase
NHPEKHJJ_01149 4.5e-62 psiE S Phosphate-starvation-inducible E
NHPEKHJJ_01150 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHPEKHJJ_01152 2.6e-177 S Aldo keto reductase
NHPEKHJJ_01153 9.9e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
NHPEKHJJ_01154 0.0 L Helicase C-terminal domain protein
NHPEKHJJ_01156 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NHPEKHJJ_01157 3.3e-55 S Sugar efflux transporter for intercellular exchange
NHPEKHJJ_01158 2.1e-126
NHPEKHJJ_01159 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NHPEKHJJ_01160 5.5e-183 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NHPEKHJJ_01161 1.3e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHPEKHJJ_01162 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NHPEKHJJ_01163 6.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NHPEKHJJ_01164 1.6e-177
NHPEKHJJ_01165 1e-130 cobB K SIR2 family
NHPEKHJJ_01167 3.6e-162 yunF F Protein of unknown function DUF72
NHPEKHJJ_01168 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHPEKHJJ_01169 1.9e-155 tatD L hydrolase, TatD family
NHPEKHJJ_01170 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHPEKHJJ_01171 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHPEKHJJ_01172 6.8e-37 veg S Biofilm formation stimulator VEG
NHPEKHJJ_01173 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHPEKHJJ_01174 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
NHPEKHJJ_01175 1.4e-121 fhuC P ABC transporter
NHPEKHJJ_01176 1.4e-118 znuB U ABC 3 transport family
NHPEKHJJ_01177 2.6e-149 purR 2.4.2.7 F pur operon repressor
NHPEKHJJ_01178 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHPEKHJJ_01179 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHPEKHJJ_01180 2.1e-49
NHPEKHJJ_01181 1.8e-145 yxeH S hydrolase
NHPEKHJJ_01182 5e-270 ywfO S HD domain protein
NHPEKHJJ_01183 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NHPEKHJJ_01184 3e-66 ywiB S Domain of unknown function (DUF1934)
NHPEKHJJ_01185 8.6e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHPEKHJJ_01186 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHPEKHJJ_01187 5.9e-114 L PFAM Integrase catalytic region
NHPEKHJJ_01188 1.7e-133 K Transcriptional regulatory protein, C-terminal domain protein
NHPEKHJJ_01189 2.5e-158 pstS P Phosphate
NHPEKHJJ_01190 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
NHPEKHJJ_01191 3.6e-152 pstA P Phosphate transport system permease protein PstA
NHPEKHJJ_01192 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHPEKHJJ_01193 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
NHPEKHJJ_01194 2.1e-141
NHPEKHJJ_01195 6.7e-44 ydaM M Glycosyl transferase
NHPEKHJJ_01196 1.1e-181 ydaM M Glycosyl transferase
NHPEKHJJ_01197 7.4e-219 G Glycosyl hydrolases family 8
NHPEKHJJ_01198 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NHPEKHJJ_01199 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NHPEKHJJ_01200 1.7e-238 ktrB P Potassium uptake protein
NHPEKHJJ_01201 1.4e-116 ktrA P domain protein
NHPEKHJJ_01202 1.2e-81 Q Methyltransferase
NHPEKHJJ_01203 8.2e-230 mntH P H( )-stimulated, divalent metal cation uptake system
NHPEKHJJ_01204 5.7e-82 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NHPEKHJJ_01205 2.6e-68 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NHPEKHJJ_01206 7.4e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHPEKHJJ_01207 1.3e-96 S NADPH-dependent FMN reductase
NHPEKHJJ_01208 6.1e-216 G Belongs to the glycosyl hydrolase family 6
NHPEKHJJ_01209 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
NHPEKHJJ_01210 3.5e-134 I alpha/beta hydrolase fold
NHPEKHJJ_01211 1e-54 lsa S ABC transporter
NHPEKHJJ_01212 1.2e-82 lsa S ABC transporter
NHPEKHJJ_01213 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NHPEKHJJ_01214 3.7e-54
NHPEKHJJ_01215 9.9e-206 yttB EGP Major facilitator Superfamily
NHPEKHJJ_01216 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NHPEKHJJ_01217 2e-74 rplI J Binds to the 23S rRNA
NHPEKHJJ_01218 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NHPEKHJJ_01219 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHPEKHJJ_01220 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHPEKHJJ_01221 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NHPEKHJJ_01222 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHPEKHJJ_01223 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHPEKHJJ_01224 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHPEKHJJ_01225 1.7e-34 yaaA S S4 domain protein YaaA
NHPEKHJJ_01226 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NHPEKHJJ_01227 1.6e-81 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NHPEKHJJ_01228 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHPEKHJJ_01229 6.5e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHPEKHJJ_01230 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NHPEKHJJ_01231 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHPEKHJJ_01232 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHPEKHJJ_01233 9.7e-130 jag S R3H domain protein
NHPEKHJJ_01234 1.3e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHPEKHJJ_01235 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHPEKHJJ_01236 0.0 asnB 6.3.5.4 E Asparagine synthase
NHPEKHJJ_01237 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHPEKHJJ_01238 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
NHPEKHJJ_01239 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NHPEKHJJ_01240 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
NHPEKHJJ_01241 1.8e-161 S reductase
NHPEKHJJ_01243 3.6e-288 S amidohydrolase
NHPEKHJJ_01244 1.6e-260 K Aminotransferase class I and II
NHPEKHJJ_01245 7.5e-83 azlC E azaleucine resistance protein AzlC
NHPEKHJJ_01246 7.1e-50 azlD E Branched-chain amino acid transport
NHPEKHJJ_01247 5.5e-118 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NHPEKHJJ_01249 2.7e-70 S GyrI-like small molecule binding domain
NHPEKHJJ_01250 6.4e-39 S GyrI-like small molecule binding domain
NHPEKHJJ_01251 5e-122 yhiD S MgtC family
NHPEKHJJ_01252 3.9e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NHPEKHJJ_01253 5.9e-191 V Beta-lactamase
NHPEKHJJ_01255 4.4e-100 L Helix-turn-helix domain
NHPEKHJJ_01258 2.2e-12
NHPEKHJJ_01273 3.4e-29 L Psort location Cytoplasmic, score
NHPEKHJJ_01281 7.6e-12 S protein disulfide oxidoreductase activity
NHPEKHJJ_01282 1.6e-10 E Zn peptidase
NHPEKHJJ_01283 6.6e-77 L Belongs to the 'phage' integrase family
NHPEKHJJ_01285 2.2e-154 P Belongs to the nlpA lipoprotein family
NHPEKHJJ_01286 3.9e-12
NHPEKHJJ_01287 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NHPEKHJJ_01288 1.4e-294 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHPEKHJJ_01289 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
NHPEKHJJ_01290 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHPEKHJJ_01291 5.9e-22 S Protein of unknown function (DUF3042)
NHPEKHJJ_01292 3.4e-67 yqhL P Rhodanese-like protein
NHPEKHJJ_01293 5.6e-183 glk 2.7.1.2 G Glucokinase
NHPEKHJJ_01294 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NHPEKHJJ_01295 3.8e-46 gluP 3.4.21.105 S Peptidase, S54 family
NHPEKHJJ_01296 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
NHPEKHJJ_01297 1.7e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHPEKHJJ_01298 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHPEKHJJ_01299 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NHPEKHJJ_01300 0.0 S membrane
NHPEKHJJ_01301 8.8e-71 yneR S Belongs to the HesB IscA family
NHPEKHJJ_01302 4.5e-48 L PFAM transposase IS200-family protein
NHPEKHJJ_01303 9.2e-74 L hmm pf00665
NHPEKHJJ_01304 9e-23 UW LPXTG-motif cell wall anchor domain protein
NHPEKHJJ_01305 6.5e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHPEKHJJ_01306 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHPEKHJJ_01307 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHPEKHJJ_01308 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHPEKHJJ_01309 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHPEKHJJ_01310 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHPEKHJJ_01311 2.2e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHPEKHJJ_01312 5.5e-217 patA 2.6.1.1 E Aminotransferase
NHPEKHJJ_01313 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHPEKHJJ_01314 8.5e-84 KT Putative sugar diacid recognition
NHPEKHJJ_01315 1.7e-219 EG GntP family permease
NHPEKHJJ_01316 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NHPEKHJJ_01317 7.7e-58
NHPEKHJJ_01319 1.2e-133 mltD CBM50 M NlpC P60 family protein
NHPEKHJJ_01320 5.7e-29
NHPEKHJJ_01321 1.3e-179 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NHPEKHJJ_01322 9.8e-32 ykzG S Belongs to the UPF0356 family
NHPEKHJJ_01323 2.4e-78
NHPEKHJJ_01324 8.6e-202 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHPEKHJJ_01325 1.3e-130 2.4.1.52 GT4 M Glycosyl transferases group 1
NHPEKHJJ_01326 7e-14 L Integrase core domain
NHPEKHJJ_01327 2e-192 L Integrase core domain
NHPEKHJJ_01328 8.2e-126 O Bacterial dnaA protein
NHPEKHJJ_01329 3.2e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NHPEKHJJ_01332 2e-194 L Integrase core domain
NHPEKHJJ_01354 1.6e-235 L Integrase core domain
NHPEKHJJ_01355 1.6e-25 L helicase activity
NHPEKHJJ_01356 4.8e-38 L helicase activity
NHPEKHJJ_01358 1.8e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHPEKHJJ_01359 2.9e-18
NHPEKHJJ_01360 6.2e-208 rny S Endoribonuclease that initiates mRNA decay
NHPEKHJJ_01361 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHPEKHJJ_01362 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHPEKHJJ_01363 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHPEKHJJ_01364 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHPEKHJJ_01365 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHPEKHJJ_01366 2.8e-31 yajC U Preprotein translocase
NHPEKHJJ_01367 3.6e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NHPEKHJJ_01368 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHPEKHJJ_01369 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHPEKHJJ_01370 4.1e-43 yrzL S Belongs to the UPF0297 family
NHPEKHJJ_01371 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHPEKHJJ_01372 6.1e-48 yrzB S Belongs to the UPF0473 family
NHPEKHJJ_01373 1e-85 cvpA S Colicin V production protein
NHPEKHJJ_01374 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHPEKHJJ_01375 6.1e-54 trxA O Belongs to the thioredoxin family
NHPEKHJJ_01376 1.3e-96 yslB S Protein of unknown function (DUF2507)
NHPEKHJJ_01377 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NHPEKHJJ_01378 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHPEKHJJ_01379 4.4e-94 S Phosphoesterase
NHPEKHJJ_01380 3.6e-76 ykuL S (CBS) domain
NHPEKHJJ_01381 4.4e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NHPEKHJJ_01382 3.4e-147 ykuT M mechanosensitive ion channel
NHPEKHJJ_01383 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHPEKHJJ_01384 3.5e-26
NHPEKHJJ_01385 1.2e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NHPEKHJJ_01386 1.4e-181 ccpA K catabolite control protein A
NHPEKHJJ_01387 1.9e-134
NHPEKHJJ_01388 3.5e-132 yebC K Transcriptional regulatory protein
NHPEKHJJ_01389 3e-78 S Fic/DOC family
NHPEKHJJ_01390 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHPEKHJJ_01391 1.7e-183 S Phosphotransferase system, EIIC
NHPEKHJJ_01392 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NHPEKHJJ_01393 7.9e-35 copZ C Heavy-metal-associated domain
NHPEKHJJ_01394 6.7e-93 dps P Belongs to the Dps family
NHPEKHJJ_01395 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NHPEKHJJ_01396 4.2e-111 3.6.1.13, 3.6.1.55 F NUDIX domain
NHPEKHJJ_01397 4e-230 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHPEKHJJ_01398 5.6e-79 pncA Q Isochorismatase family
NHPEKHJJ_01399 7.9e-61 pldB 3.1.1.5 I Serine aminopeptidase, S33
NHPEKHJJ_01400 2.7e-26 K TRANSCRIPTIONal
NHPEKHJJ_01401 5.5e-75 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHPEKHJJ_01402 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHPEKHJJ_01403 2.1e-165 yniA G Phosphotransferase enzyme family
NHPEKHJJ_01404 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHPEKHJJ_01405 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHPEKHJJ_01406 1.2e-52
NHPEKHJJ_01407 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHPEKHJJ_01408 5.9e-177 prmA J Ribosomal protein L11 methyltransferase
NHPEKHJJ_01409 2.8e-57
NHPEKHJJ_01410 8.7e-148 1.1.1.346 C Aldo keto reductase
NHPEKHJJ_01411 6.8e-139 K LysR substrate binding domain protein
NHPEKHJJ_01412 1.5e-80 C Flavodoxin
NHPEKHJJ_01413 7.5e-77 yphH S Cupin domain
NHPEKHJJ_01414 1.7e-73 yeaL S UPF0756 membrane protein
NHPEKHJJ_01415 6.9e-243 EGP Major facilitator Superfamily
NHPEKHJJ_01416 5e-75 copY K Copper transport repressor CopY TcrY
NHPEKHJJ_01417 8.5e-246 yhdP S Transporter associated domain
NHPEKHJJ_01418 0.0 ubiB S ABC1 family
NHPEKHJJ_01419 8.1e-143 S DUF218 domain
NHPEKHJJ_01420 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPEKHJJ_01421 5.8e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPEKHJJ_01422 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPEKHJJ_01423 0.0 uvrA3 L excinuclease ABC, A subunit
NHPEKHJJ_01424 4.6e-123 S SNARE associated Golgi protein
NHPEKHJJ_01425 1.3e-229 N Uncharacterized conserved protein (DUF2075)
NHPEKHJJ_01426 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHPEKHJJ_01428 1e-254 yifK E Amino acid permease
NHPEKHJJ_01429 5.5e-158 endA V DNA/RNA non-specific endonuclease
NHPEKHJJ_01430 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHPEKHJJ_01431 3.9e-27 mleP3 S Membrane transport protein
NHPEKHJJ_01432 7.3e-121 T Transcriptional regulatory protein, C terminal
NHPEKHJJ_01433 9.9e-239 T GHKL domain
NHPEKHJJ_01434 3e-108 S Peptidase propeptide and YPEB domain
NHPEKHJJ_01435 2e-74 P FAD-binding domain
NHPEKHJJ_01436 4.3e-55 yphJ 4.1.1.44 S decarboxylase
NHPEKHJJ_01437 5.3e-83 K Bacterial regulatory proteins, tetR family
NHPEKHJJ_01438 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NHPEKHJJ_01439 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
NHPEKHJJ_01440 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
NHPEKHJJ_01441 2.7e-85 C Flavodoxin
NHPEKHJJ_01442 5.6e-158 K Transcriptional regulator
NHPEKHJJ_01443 6.3e-88 lacA S transferase hexapeptide repeat
NHPEKHJJ_01444 9.4e-32 S thiolester hydrolase activity
NHPEKHJJ_01445 2e-152 S Alpha beta hydrolase
NHPEKHJJ_01446 2.3e-93 padC Q Phenolic acid decarboxylase
NHPEKHJJ_01447 3.3e-92 padR K Virulence activator alpha C-term
NHPEKHJJ_01448 4.7e-66 GM NAD(P)H-binding
NHPEKHJJ_01449 2.3e-155 ypuA S Protein of unknown function (DUF1002)
NHPEKHJJ_01450 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
NHPEKHJJ_01451 4.3e-59 K Transcriptional regulator
NHPEKHJJ_01452 4.3e-40 K Transcriptional regulator
NHPEKHJJ_01453 6.5e-28 akr5f 1.1.1.346 S reductase
NHPEKHJJ_01454 3.2e-118 akr5f 1.1.1.346 S reductase
NHPEKHJJ_01455 1.8e-104 K Transcriptional regulator C-terminal region
NHPEKHJJ_01456 1e-73 S membrane
NHPEKHJJ_01457 6.1e-88 S membrane
NHPEKHJJ_01458 1.2e-112 GM NAD(P)H-binding
NHPEKHJJ_01459 1.1e-64 yneR
NHPEKHJJ_01460 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
NHPEKHJJ_01461 3.7e-140 T EAL domain
NHPEKHJJ_01462 1.2e-252 pgaC GT2 M Glycosyl transferase
NHPEKHJJ_01463 5.2e-84
NHPEKHJJ_01466 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NHPEKHJJ_01467 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHPEKHJJ_01468 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHPEKHJJ_01469 2e-202 coiA 3.6.4.12 S Competence protein
NHPEKHJJ_01470 9.2e-264 pipD E Dipeptidase
NHPEKHJJ_01471 4.7e-114 yjbH Q Thioredoxin
NHPEKHJJ_01472 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
NHPEKHJJ_01473 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHPEKHJJ_01474 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NHPEKHJJ_01483 2.1e-41 ybaN S Protein of unknown function (DUF454)
NHPEKHJJ_01484 3.1e-72 S Protein of unknown function (DUF3290)
NHPEKHJJ_01485 6.2e-114 yviA S Protein of unknown function (DUF421)
NHPEKHJJ_01486 4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
NHPEKHJJ_01487 1.3e-20
NHPEKHJJ_01488 8.1e-90 ntd 2.4.2.6 F Nucleoside
NHPEKHJJ_01489 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
NHPEKHJJ_01490 1.6e-45 yrvD S Pfam:DUF1049
NHPEKHJJ_01492 1.1e-35 S Phage derived protein Gp49-like (DUF891)
NHPEKHJJ_01493 8.5e-20 K Helix-turn-helix XRE-family like proteins
NHPEKHJJ_01494 1.7e-78 I alpha/beta hydrolase fold
NHPEKHJJ_01495 1.1e-113 frnE Q DSBA-like thioredoxin domain
NHPEKHJJ_01496 1.4e-51
NHPEKHJJ_01497 2.1e-188 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHPEKHJJ_01498 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHPEKHJJ_01499 9.9e-261 yfnA E amino acid
NHPEKHJJ_01500 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NHPEKHJJ_01501 9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHPEKHJJ_01502 2e-39 ylqC S Belongs to the UPF0109 family
NHPEKHJJ_01503 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NHPEKHJJ_01504 2.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHPEKHJJ_01505 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHPEKHJJ_01506 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHPEKHJJ_01507 0.0 smc D Required for chromosome condensation and partitioning
NHPEKHJJ_01508 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHPEKHJJ_01509 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHPEKHJJ_01510 6.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHPEKHJJ_01511 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHPEKHJJ_01512 7.1e-311 yloV S DAK2 domain fusion protein YloV
NHPEKHJJ_01513 4.7e-58 asp S Asp23 family, cell envelope-related function
NHPEKHJJ_01514 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NHPEKHJJ_01515 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NHPEKHJJ_01516 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NHPEKHJJ_01517 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHPEKHJJ_01518 0.0 KLT serine threonine protein kinase
NHPEKHJJ_01519 6.5e-131 stp 3.1.3.16 T phosphatase
NHPEKHJJ_01520 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHPEKHJJ_01521 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHPEKHJJ_01522 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHPEKHJJ_01523 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHPEKHJJ_01524 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHPEKHJJ_01525 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NHPEKHJJ_01526 1.7e-54
NHPEKHJJ_01527 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
NHPEKHJJ_01528 3.1e-75 argR K Regulates arginine biosynthesis genes
NHPEKHJJ_01529 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NHPEKHJJ_01530 1.1e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHPEKHJJ_01531 2.1e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHPEKHJJ_01532 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHPEKHJJ_01533 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHPEKHJJ_01534 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHPEKHJJ_01535 2.2e-70 yqhY S Asp23 family, cell envelope-related function
NHPEKHJJ_01536 1.7e-114 J 2'-5' RNA ligase superfamily
NHPEKHJJ_01537 5.1e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NHPEKHJJ_01538 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHPEKHJJ_01539 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NHPEKHJJ_01540 1.6e-54 ysxB J Cysteine protease Prp
NHPEKHJJ_01541 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NHPEKHJJ_01542 1.8e-110 K Transcriptional regulator
NHPEKHJJ_01545 2.5e-89 dut S Protein conserved in bacteria
NHPEKHJJ_01546 6.6e-174
NHPEKHJJ_01547 1e-151
NHPEKHJJ_01548 3.7e-51 S Iron-sulfur cluster assembly protein
NHPEKHJJ_01549 4.7e-90 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHPEKHJJ_01550 6e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHPEKHJJ_01551 4.7e-10 T PFAM SpoVT AbrB
NHPEKHJJ_01552 5.5e-183 M lysozyme activity
NHPEKHJJ_01553 6.2e-18 S Bacteriophage holin family
NHPEKHJJ_01554 4.8e-12
NHPEKHJJ_01556 3e-308 GT2,GT4 LM gp58-like protein
NHPEKHJJ_01557 8.4e-52
NHPEKHJJ_01558 0.0 M Phage tail tape measure protein TP901
NHPEKHJJ_01559 8.8e-33
NHPEKHJJ_01560 3.4e-57
NHPEKHJJ_01561 5.9e-72 S Phage tail tube protein, TTP
NHPEKHJJ_01562 3e-44
NHPEKHJJ_01563 6.2e-78
NHPEKHJJ_01564 1.2e-58
NHPEKHJJ_01565 3.6e-35
NHPEKHJJ_01566 1.6e-167 S Phage major capsid protein E
NHPEKHJJ_01567 4.2e-54
NHPEKHJJ_01568 1.5e-51 S Domain of unknown function (DUF4355)
NHPEKHJJ_01569 8.1e-151 S Phage Mu protein F like protein
NHPEKHJJ_01570 5.5e-214 S Phage portal protein, SPP1 Gp6-like
NHPEKHJJ_01571 4.1e-218 S Terminase-like family
NHPEKHJJ_01572 2.3e-119 xtmA L Terminase small subunit
NHPEKHJJ_01575 3.5e-69 S Domain of unknown function (DUF4417)
NHPEKHJJ_01580 6.6e-37
NHPEKHJJ_01581 2.5e-07
NHPEKHJJ_01584 1.8e-61 rusA L Endodeoxyribonuclease RusA
NHPEKHJJ_01585 2.6e-16
NHPEKHJJ_01591 2.1e-51 S ORF6C domain
NHPEKHJJ_01594 1.7e-54
NHPEKHJJ_01595 1.9e-121 L Psort location Cytoplasmic, score
NHPEKHJJ_01596 1.1e-57 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NHPEKHJJ_01597 5.5e-79 recT L RecT family
NHPEKHJJ_01608 1.8e-14 K Cro/C1-type HTH DNA-binding domain
NHPEKHJJ_01611 6.2e-18
NHPEKHJJ_01616 4.4e-26 3.4.21.88 K Helix-turn-helix domain
NHPEKHJJ_01617 4.6e-70 S Pfam:DUF955
NHPEKHJJ_01618 2.8e-07
NHPEKHJJ_01621 5.4e-09
NHPEKHJJ_01622 1e-38
NHPEKHJJ_01623 7.7e-49
NHPEKHJJ_01624 3.7e-210 L Belongs to the 'phage' integrase family
NHPEKHJJ_01625 8.7e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHPEKHJJ_01626 2.7e-39 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHPEKHJJ_01627 8.4e-156 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHPEKHJJ_01628 1.4e-264 argH 4.3.2.1 E argininosuccinate lyase
NHPEKHJJ_01629 1.1e-90 bioY S BioY family
NHPEKHJJ_01630 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHPEKHJJ_01631 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
NHPEKHJJ_01632 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHPEKHJJ_01633 9.9e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NHPEKHJJ_01634 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHPEKHJJ_01635 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
NHPEKHJJ_01636 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NHPEKHJJ_01637 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NHPEKHJJ_01638 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHPEKHJJ_01639 1.9e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHPEKHJJ_01640 1.2e-219 patA 2.6.1.1 E Aminotransferase
NHPEKHJJ_01641 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
NHPEKHJJ_01642 5.9e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHPEKHJJ_01643 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHPEKHJJ_01644 3e-30 S Protein of unknown function (DUF2929)
NHPEKHJJ_01645 0.0 dnaE 2.7.7.7 L DNA polymerase
NHPEKHJJ_01646 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NHPEKHJJ_01647 2.3e-167 cvfB S S1 domain
NHPEKHJJ_01648 4.5e-163 xerD D recombinase XerD
NHPEKHJJ_01649 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPEKHJJ_01650 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHPEKHJJ_01651 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHPEKHJJ_01652 5.8e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHPEKHJJ_01653 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHPEKHJJ_01654 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
NHPEKHJJ_01655 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NHPEKHJJ_01656 8.5e-14 M Lysin motif
NHPEKHJJ_01657 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NHPEKHJJ_01658 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NHPEKHJJ_01659 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NHPEKHJJ_01660 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHPEKHJJ_01661 1.5e-236 S Tetratricopeptide repeat protein
NHPEKHJJ_01662 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHPEKHJJ_01663 0.0 yfmR S ABC transporter, ATP-binding protein
NHPEKHJJ_01664 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHPEKHJJ_01665 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHPEKHJJ_01666 5.3e-113 hlyIII S protein, hemolysin III
NHPEKHJJ_01667 1.7e-151 DegV S EDD domain protein, DegV family
NHPEKHJJ_01668 9.5e-172 ypmR E lipolytic protein G-D-S-L family
NHPEKHJJ_01669 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NHPEKHJJ_01670 4.4e-35 yozE S Belongs to the UPF0346 family
NHPEKHJJ_01671 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHPEKHJJ_01672 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHPEKHJJ_01673 2.4e-161 dprA LU DNA protecting protein DprA
NHPEKHJJ_01674 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHPEKHJJ_01675 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
NHPEKHJJ_01676 5.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHPEKHJJ_01677 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHPEKHJJ_01678 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHPEKHJJ_01679 4.9e-84 F NUDIX domain
NHPEKHJJ_01680 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
NHPEKHJJ_01682 5.1e-139 L Bacterial dnaA protein
NHPEKHJJ_01683 1.3e-146 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NHPEKHJJ_01684 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NHPEKHJJ_01685 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
NHPEKHJJ_01686 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NHPEKHJJ_01687 3e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NHPEKHJJ_01690 1.3e-30
NHPEKHJJ_01693 1.4e-07 V CAAX protease self-immunity
NHPEKHJJ_01696 2.2e-51 trwN GH23 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHPEKHJJ_01698 1.3e-194 U type IV secretory pathway VirB4
NHPEKHJJ_01699 2.9e-29
NHPEKHJJ_01701 1.2e-68
NHPEKHJJ_01702 1e-232 U TraM recognition site of TraD and TraG
NHPEKHJJ_01705 3.1e-77 L PFAM Integrase catalytic region
NHPEKHJJ_01706 3.5e-85 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NHPEKHJJ_01707 2.3e-67 gtcA S Teichoic acid glycosylation protein
NHPEKHJJ_01708 6.1e-79 fld C Flavodoxin
NHPEKHJJ_01709 3.8e-167 map 3.4.11.18 E Methionine Aminopeptidase
NHPEKHJJ_01710 1.7e-220 arcT 2.6.1.1 E Aminotransferase
NHPEKHJJ_01711 3.6e-255 E Arginine ornithine antiporter
NHPEKHJJ_01712 1.1e-281 yjeM E Amino Acid
NHPEKHJJ_01713 3.2e-153 yihY S Belongs to the UPF0761 family
NHPEKHJJ_01714 6.6e-34 S Protein of unknown function (DUF2922)
NHPEKHJJ_01715 4.9e-31
NHPEKHJJ_01716 7.9e-127 recX 2.4.1.337 GT4 S Regulatory protein RecX
NHPEKHJJ_01717 4.3e-146 cps1D M Domain of unknown function (DUF4422)
NHPEKHJJ_01718 1.1e-172 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NHPEKHJJ_01719 3.8e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
NHPEKHJJ_01720 1.6e-62 cps3F
NHPEKHJJ_01721 1.2e-34 M biosynthesis protein
NHPEKHJJ_01722 3.6e-66 M Domain of unknown function (DUF4422)
NHPEKHJJ_01723 1.5e-78 M Core-2/I-Branching enzyme
NHPEKHJJ_01724 3.5e-153 ykoT GT2 M Glycosyl transferase family 2
NHPEKHJJ_01725 7.6e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
NHPEKHJJ_01726 3.1e-230 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NHPEKHJJ_01727 3e-73 waaB GT4 M Glycosyl transferases group 1
NHPEKHJJ_01728 3.3e-51 cps3I G Acyltransferase family
NHPEKHJJ_01729 5.4e-181 galR K Transcriptional regulator
NHPEKHJJ_01730 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NHPEKHJJ_01731 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHPEKHJJ_01732 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NHPEKHJJ_01733 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
NHPEKHJJ_01734 1.8e-92 yxkA S Phosphatidylethanolamine-binding protein
NHPEKHJJ_01735 3.4e-35
NHPEKHJJ_01736 9.1e-53
NHPEKHJJ_01737 8.7e-204
NHPEKHJJ_01738 3.7e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHPEKHJJ_01739 4.4e-135 pnuC H nicotinamide mononucleotide transporter
NHPEKHJJ_01740 1.9e-155 ytbE 1.1.1.346 S Aldo keto reductase
NHPEKHJJ_01741 1.2e-123 K response regulator
NHPEKHJJ_01742 3.8e-179 T PhoQ Sensor
NHPEKHJJ_01743 2.1e-132 macB2 V ABC transporter, ATP-binding protein
NHPEKHJJ_01744 0.0 ysaB V FtsX-like permease family
NHPEKHJJ_01745 5.3e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NHPEKHJJ_01746 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHPEKHJJ_01747 4.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHPEKHJJ_01748 2.1e-197 EGP Major facilitator Superfamily
NHPEKHJJ_01749 5.6e-86 ymdB S Macro domain protein
NHPEKHJJ_01750 3.2e-110 K Helix-turn-helix domain
NHPEKHJJ_01751 0.0 pepO 3.4.24.71 O Peptidase family M13
NHPEKHJJ_01752 1.8e-47
NHPEKHJJ_01753 8.7e-240 S Putative metallopeptidase domain
NHPEKHJJ_01754 3e-204 3.1.3.1 S associated with various cellular activities
NHPEKHJJ_01755 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NHPEKHJJ_01756 1.6e-64 yeaO S Protein of unknown function, DUF488
NHPEKHJJ_01757 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NHPEKHJJ_01758 3.3e-46 gcvH E glycine cleavage
NHPEKHJJ_01759 4.1e-220 rodA D Belongs to the SEDS family
NHPEKHJJ_01760 1e-31 S Protein of unknown function (DUF2969)
NHPEKHJJ_01761 1.9e-178 mbl D Cell shape determining protein MreB Mrl
NHPEKHJJ_01762 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHPEKHJJ_01763 1.3e-33 ywzB S Protein of unknown function (DUF1146)
NHPEKHJJ_01764 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NHPEKHJJ_01765 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHPEKHJJ_01766 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHPEKHJJ_01767 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHPEKHJJ_01768 6.7e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHPEKHJJ_01769 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHPEKHJJ_01770 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHPEKHJJ_01771 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
NHPEKHJJ_01772 2.5e-231 pyrP F Permease
NHPEKHJJ_01773 6.3e-129 yibF S overlaps another CDS with the same product name
NHPEKHJJ_01774 9.9e-192 yibE S overlaps another CDS with the same product name
NHPEKHJJ_01775 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHPEKHJJ_01776 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHPEKHJJ_01777 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHPEKHJJ_01778 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHPEKHJJ_01779 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHPEKHJJ_01780 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHPEKHJJ_01781 6e-108 tdk 2.7.1.21 F thymidine kinase
NHPEKHJJ_01782 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NHPEKHJJ_01783 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NHPEKHJJ_01784 2.7e-223 arcD U Amino acid permease
NHPEKHJJ_01785 2e-261 E Arginine ornithine antiporter
NHPEKHJJ_01786 4.7e-79 argR K Regulates arginine biosynthesis genes
NHPEKHJJ_01787 4.1e-239 arcA 3.5.3.6 E Arginine
NHPEKHJJ_01788 3.9e-187 ampC V Beta-lactamase
NHPEKHJJ_01789 1.9e-32
NHPEKHJJ_01790 0.0 M domain protein
NHPEKHJJ_01791 5.9e-91
NHPEKHJJ_01793 2.7e-158 yjcE P Sodium proton antiporter
NHPEKHJJ_01794 1e-73 yjcE P Sodium proton antiporter
NHPEKHJJ_01796 5.2e-56
NHPEKHJJ_01798 4.5e-85
NHPEKHJJ_01799 0.0 copA 3.6.3.54 P P-type ATPase
NHPEKHJJ_01800 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NHPEKHJJ_01801 2.5e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NHPEKHJJ_01802 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NHPEKHJJ_01803 3.3e-161 EG EamA-like transporter family
NHPEKHJJ_01804 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NHPEKHJJ_01805 9.9e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHPEKHJJ_01806 8.1e-154 KT YcbB domain
NHPEKHJJ_01807 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
NHPEKHJJ_01808 5.6e-164 xylR GK ROK family
NHPEKHJJ_01809 1.3e-28
NHPEKHJJ_01810 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
NHPEKHJJ_01811 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
NHPEKHJJ_01812 2.6e-155 glcU U sugar transport
NHPEKHJJ_01813 6.8e-273 yclK 2.7.13.3 T Histidine kinase
NHPEKHJJ_01814 1.5e-132 K response regulator
NHPEKHJJ_01816 2.8e-79 lytE M Lysin motif
NHPEKHJJ_01817 2e-149 XK27_02985 S Cof-like hydrolase
NHPEKHJJ_01818 2.3e-81 K Transcriptional regulator
NHPEKHJJ_01819 0.0 oatA I Acyltransferase
NHPEKHJJ_01820 8.7e-53
NHPEKHJJ_01821 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHPEKHJJ_01822 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHPEKHJJ_01823 2e-126 ybbR S YbbR-like protein
NHPEKHJJ_01824 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHPEKHJJ_01825 6.1e-244 fucP G Major Facilitator Superfamily
NHPEKHJJ_01826 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NHPEKHJJ_01827 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHPEKHJJ_01828 3.6e-168 murB 1.3.1.98 M Cell wall formation
NHPEKHJJ_01829 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
NHPEKHJJ_01830 4.4e-76 S PAS domain
NHPEKHJJ_01831 2.6e-86 K Acetyltransferase (GNAT) domain
NHPEKHJJ_01832 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NHPEKHJJ_01833 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NHPEKHJJ_01834 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHPEKHJJ_01835 6.3e-105 yxjI
NHPEKHJJ_01836 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHPEKHJJ_01837 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHPEKHJJ_01838 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
NHPEKHJJ_01839 1.8e-34 secG U Preprotein translocase
NHPEKHJJ_01840 2.6e-291 clcA P chloride
NHPEKHJJ_01841 7.1e-248 yifK E Amino acid permease
NHPEKHJJ_01842 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHPEKHJJ_01843 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHPEKHJJ_01844 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NHPEKHJJ_01845 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHPEKHJJ_01847 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHPEKHJJ_01848 8.8e-15
NHPEKHJJ_01850 4e-170 whiA K May be required for sporulation
NHPEKHJJ_01851 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NHPEKHJJ_01852 1.1e-161 rapZ S Displays ATPase and GTPase activities
NHPEKHJJ_01853 5.4e-245 steT E amino acid
NHPEKHJJ_01854 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHPEKHJJ_01855 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHPEKHJJ_01856 1.5e-13
NHPEKHJJ_01857 2.3e-116 yfbR S HD containing hydrolase-like enzyme
NHPEKHJJ_01858 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NHPEKHJJ_01859 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
NHPEKHJJ_01860 1.3e-157 aatB ET PFAM extracellular solute-binding protein, family 3
NHPEKHJJ_01861 2.5e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NHPEKHJJ_01862 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHPEKHJJ_01863 6.8e-158 lutA C Cysteine-rich domain
NHPEKHJJ_01864 7.5e-288 lutB C 4Fe-4S dicluster domain
NHPEKHJJ_01865 3.9e-136 yrjD S LUD domain
NHPEKHJJ_01866 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHPEKHJJ_01867 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NHPEKHJJ_01868 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHPEKHJJ_01869 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHPEKHJJ_01870 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NHPEKHJJ_01871 3.1e-32 KT PspC domain protein
NHPEKHJJ_01872 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHPEKHJJ_01873 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHPEKHJJ_01874 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHPEKHJJ_01875 1.2e-112 comFC S Competence protein
NHPEKHJJ_01876 6.8e-256 comFA L Helicase C-terminal domain protein
NHPEKHJJ_01877 2.9e-111 yvyE 3.4.13.9 S YigZ family
NHPEKHJJ_01878 1.6e-236 EGP Major facilitator Superfamily
NHPEKHJJ_01879 3.5e-35
NHPEKHJJ_01880 3.2e-83 F Belongs to the NrdI family
NHPEKHJJ_01881 1.2e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NHPEKHJJ_01882 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
NHPEKHJJ_01883 1.5e-65 esbA S Family of unknown function (DUF5322)
NHPEKHJJ_01884 1.3e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHPEKHJJ_01885 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHPEKHJJ_01886 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
NHPEKHJJ_01887 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NHPEKHJJ_01888 2.1e-39 gcvR T Belongs to the UPF0237 family
NHPEKHJJ_01889 4e-240 XK27_08635 S UPF0210 protein
NHPEKHJJ_01890 1.5e-94 K Acetyltransferase (GNAT) domain
NHPEKHJJ_01891 1.2e-160 S Alpha beta hydrolase
NHPEKHJJ_01892 1.1e-158 gspA M family 8
NHPEKHJJ_01893 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHPEKHJJ_01894 3.8e-93
NHPEKHJJ_01895 1.7e-162 degV S EDD domain protein, DegV family
NHPEKHJJ_01896 0.0 FbpA K Fibronectin-binding protein
NHPEKHJJ_01897 5.5e-110 dedA S SNARE-like domain protein
NHPEKHJJ_01898 7e-105 S Protein of unknown function (DUF1461)
NHPEKHJJ_01899 1.6e-132 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHPEKHJJ_01900 1.3e-93 yutD S Protein of unknown function (DUF1027)
NHPEKHJJ_01901 2.2e-113 S Calcineurin-like phosphoesterase
NHPEKHJJ_01902 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHPEKHJJ_01903 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
NHPEKHJJ_01905 6.3e-70
NHPEKHJJ_01906 2.7e-40
NHPEKHJJ_01907 8.3e-78 NU general secretion pathway protein
NHPEKHJJ_01908 7.1e-47 comGC U competence protein ComGC
NHPEKHJJ_01909 9.5e-181 comGB NU type II secretion system
NHPEKHJJ_01910 2.6e-180 comGA NU Type II IV secretion system protein
NHPEKHJJ_01911 2.9e-34
NHPEKHJJ_01912 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
NHPEKHJJ_01913 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
NHPEKHJJ_01914 3.3e-83
NHPEKHJJ_01915 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NHPEKHJJ_01916 7.5e-113 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHPEKHJJ_01917 3e-17 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHPEKHJJ_01918 9.5e-112 S Membrane
NHPEKHJJ_01919 1.2e-64 O Zinc-dependent metalloprotease
NHPEKHJJ_01920 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHPEKHJJ_01921 1.6e-157 metQ_4 P Belongs to the nlpA lipoprotein family
NHPEKHJJ_01923 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NHPEKHJJ_01924 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHPEKHJJ_01925 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NHPEKHJJ_01926 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHPEKHJJ_01927 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHPEKHJJ_01928 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHPEKHJJ_01929 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHPEKHJJ_01930 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHPEKHJJ_01931 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHPEKHJJ_01932 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
NHPEKHJJ_01933 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHPEKHJJ_01934 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHPEKHJJ_01935 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHPEKHJJ_01936 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHPEKHJJ_01937 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHPEKHJJ_01938 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHPEKHJJ_01939 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHPEKHJJ_01940 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHPEKHJJ_01941 2.9e-24 rpmD J Ribosomal protein L30
NHPEKHJJ_01942 8.9e-64 rplO J Binds to the 23S rRNA
NHPEKHJJ_01943 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHPEKHJJ_01944 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHPEKHJJ_01945 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHPEKHJJ_01946 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NHPEKHJJ_01947 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHPEKHJJ_01948 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHPEKHJJ_01949 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPEKHJJ_01950 1.1e-62 rplQ J Ribosomal protein L17
NHPEKHJJ_01951 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPEKHJJ_01952 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPEKHJJ_01953 5.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPEKHJJ_01954 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHPEKHJJ_01955 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHPEKHJJ_01956 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NHPEKHJJ_01957 1.6e-112 IQ reductase
NHPEKHJJ_01958 2.3e-19 IQ reductase
NHPEKHJJ_01959 1.5e-112 acmC 3.2.1.96 NU mannosyl-glycoprotein
NHPEKHJJ_01960 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHPEKHJJ_01961 5.5e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NHPEKHJJ_01962 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NHPEKHJJ_01963 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHPEKHJJ_01964 3.3e-203 camS S sex pheromone
NHPEKHJJ_01965 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHPEKHJJ_01966 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHPEKHJJ_01967 5.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHPEKHJJ_01968 5.1e-187 yegS 2.7.1.107 G Lipid kinase
NHPEKHJJ_01969 7.3e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHPEKHJJ_01970 2.8e-18
NHPEKHJJ_01973 4.4e-150 polA_2 2.7.7.7 L DNA polymerase
NHPEKHJJ_01974 1.5e-95 S Protein of unknown function (DUF2815)
NHPEKHJJ_01975 4.5e-208 L Protein of unknown function (DUF2800)
NHPEKHJJ_01976 5.1e-45
NHPEKHJJ_01977 6.5e-25
NHPEKHJJ_01979 2.8e-147
NHPEKHJJ_01980 8.8e-87
NHPEKHJJ_01981 4.9e-89 3.1.21.3 L Type I restriction modification DNA specificity domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)