ORF_ID e_value Gene_name EC_number CAZy COGs Description
PIMLPMKJ_00008 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PIMLPMKJ_00009 6e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIMLPMKJ_00010 2.6e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
PIMLPMKJ_00011 9.9e-112 yjbH Q Thioredoxin
PIMLPMKJ_00012 5e-262 pipD E Dipeptidase
PIMLPMKJ_00013 3.6e-196 coiA 3.6.4.12 S Competence protein
PIMLPMKJ_00014 7.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PIMLPMKJ_00015 1.8e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIMLPMKJ_00016 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PIMLPMKJ_00017 1.8e-32 S Transglycosylase associated protein
PIMLPMKJ_00019 8.6e-179 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIMLPMKJ_00020 6.2e-222 V domain protein
PIMLPMKJ_00021 2.1e-91 K Transcriptional regulator (TetR family)
PIMLPMKJ_00022 1.2e-36 pspC KT PspC domain protein
PIMLPMKJ_00023 1.9e-147
PIMLPMKJ_00024 1.2e-16 3.2.1.14 GH18
PIMLPMKJ_00025 1.5e-82 zur P Belongs to the Fur family
PIMLPMKJ_00026 7.3e-98 gmk2 2.7.4.8 F Guanylate kinase
PIMLPMKJ_00027 2.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PIMLPMKJ_00028 6.7e-254 yfnA E Amino Acid
PIMLPMKJ_00029 1.4e-221 EGP Sugar (and other) transporter
PIMLPMKJ_00030 4.3e-223
PIMLPMKJ_00031 1.3e-204 potD P ABC transporter
PIMLPMKJ_00032 1.9e-139 potC P ABC transporter permease
PIMLPMKJ_00033 1.1e-144 potB P ABC transporter permease
PIMLPMKJ_00034 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PIMLPMKJ_00035 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PIMLPMKJ_00036 5.1e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PIMLPMKJ_00037 0.0 pacL 3.6.3.8 P P-type ATPase
PIMLPMKJ_00038 1.7e-84 dps P Belongs to the Dps family
PIMLPMKJ_00039 7.2e-256 yagE E amino acid
PIMLPMKJ_00040 3.3e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PIMLPMKJ_00041 5.4e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
PIMLPMKJ_00042 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
PIMLPMKJ_00043 4.3e-138 IQ KR domain
PIMLPMKJ_00044 2.1e-132 S membrane transporter protein
PIMLPMKJ_00045 1.1e-95 S ABC-type cobalt transport system, permease component
PIMLPMKJ_00046 2.2e-249 cbiO1 S ABC transporter, ATP-binding protein
PIMLPMKJ_00047 5.4e-113 P Cobalt transport protein
PIMLPMKJ_00048 6.2e-52 yvlA
PIMLPMKJ_00049 0.0 yjcE P Sodium proton antiporter
PIMLPMKJ_00050 1.1e-51 ypaA S Protein of unknown function (DUF1304)
PIMLPMKJ_00051 1.4e-186 D Alpha beta
PIMLPMKJ_00052 1e-72 K Transcriptional regulator
PIMLPMKJ_00053 1.2e-157
PIMLPMKJ_00054 1.9e-130 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIMLPMKJ_00055 5.3e-158 S Membrane transport protein
PIMLPMKJ_00056 1.2e-85 K FCD
PIMLPMKJ_00057 3e-254 G PTS system Galactitol-specific IIC component
PIMLPMKJ_00058 4.2e-209 EGP Major facilitator Superfamily
PIMLPMKJ_00059 5.7e-134 V ABC transporter
PIMLPMKJ_00060 8.5e-96
PIMLPMKJ_00061 5.8e-13
PIMLPMKJ_00062 3e-61
PIMLPMKJ_00063 8.1e-193 lplA 6.3.1.20 H Lipoate-protein ligase
PIMLPMKJ_00064 5.1e-81 uspA T universal stress protein
PIMLPMKJ_00065 0.0 tetP J elongation factor G
PIMLPMKJ_00066 4.1e-16 tetP J elongation factor G
PIMLPMKJ_00067 5.2e-167 GK ROK family
PIMLPMKJ_00068 2.7e-236 brnQ U Component of the transport system for branched-chain amino acids
PIMLPMKJ_00069 8.8e-136 aroD S Serine hydrolase (FSH1)
PIMLPMKJ_00070 4.5e-239 yagE E amino acid
PIMLPMKJ_00071 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PIMLPMKJ_00072 9.9e-132 gntR K UbiC transcription regulator-associated domain protein
PIMLPMKJ_00073 1.2e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PIMLPMKJ_00074 1.2e-282 pipD E Dipeptidase
PIMLPMKJ_00075 0.0 yfiC V ABC transporter
PIMLPMKJ_00076 3.6e-305 lmrA V ABC transporter, ATP-binding protein
PIMLPMKJ_00077 8.3e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIMLPMKJ_00078 2.6e-81 S ECF transporter, substrate-specific component
PIMLPMKJ_00079 9.9e-59 S Domain of unknown function (DUF4430)
PIMLPMKJ_00080 9.4e-184 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
PIMLPMKJ_00081 7.1e-119 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PIMLPMKJ_00082 1.3e-105 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
PIMLPMKJ_00083 3e-131 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PIMLPMKJ_00084 2e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
PIMLPMKJ_00085 7.1e-250 hemL 5.4.3.8 H Aminotransferase class-III
PIMLPMKJ_00086 2.2e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
PIMLPMKJ_00087 1.1e-167 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PIMLPMKJ_00088 2.3e-237 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PIMLPMKJ_00089 6.1e-79 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
PIMLPMKJ_00090 2.8e-282 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
PIMLPMKJ_00091 3.7e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
PIMLPMKJ_00092 4.4e-118 cbiQ P Cobalt transport protein
PIMLPMKJ_00093 2.5e-52 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
PIMLPMKJ_00094 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
PIMLPMKJ_00095 2.5e-124 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PIMLPMKJ_00096 1.4e-144 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
PIMLPMKJ_00097 5.6e-253 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PIMLPMKJ_00098 6.4e-126 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
PIMLPMKJ_00099 2e-129 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PIMLPMKJ_00100 4.8e-188 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
PIMLPMKJ_00101 4.9e-134 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PIMLPMKJ_00102 2.5e-95 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
PIMLPMKJ_00103 5.3e-107 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PIMLPMKJ_00104 2.1e-200 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PIMLPMKJ_00105 1.5e-121 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
PIMLPMKJ_00106 2.9e-163 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PIMLPMKJ_00107 6.8e-227 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
PIMLPMKJ_00108 1.2e-189 cobD 4.1.1.81 E Aminotransferase class I and II
PIMLPMKJ_00109 6.8e-96 cobO 2.5.1.17 S Cobalamin adenosyltransferase
PIMLPMKJ_00110 1.3e-148 XK27_04590 S NADPH-dependent FMN reductase
PIMLPMKJ_00111 1.8e-75 fld C Flavodoxin
PIMLPMKJ_00112 4.4e-71 eutP E Ethanolamine utilisation - propanediol utilisation
PIMLPMKJ_00113 6.2e-86 P Cadmium resistance transporter
PIMLPMKJ_00114 4.8e-114 pgm1 3.1.3.73 G phosphoglycerate mutase
PIMLPMKJ_00115 1.3e-140 3.1.3.48 T Pfam:Y_phosphatase3C
PIMLPMKJ_00116 3.9e-54 pduU E BMC
PIMLPMKJ_00117 9.8e-214 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIMLPMKJ_00118 6.4e-207 pduQ C Iron-containing alcohol dehydrogenase
PIMLPMKJ_00119 2.4e-267 pduP 1.2.1.87 C Aldehyde dehydrogenase family
PIMLPMKJ_00120 1.8e-78 pduO S Haem-degrading
PIMLPMKJ_00121 1.3e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
PIMLPMKJ_00122 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
PIMLPMKJ_00123 6.7e-87 S Putative propanediol utilisation
PIMLPMKJ_00124 3e-116 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
PIMLPMKJ_00125 7.6e-43 pduA_4 CQ BMC
PIMLPMKJ_00126 1.1e-61 pduK CQ BMC
PIMLPMKJ_00127 2.2e-55 pduH S Dehydratase medium subunit
PIMLPMKJ_00128 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
PIMLPMKJ_00129 4.1e-76 pduE 4.2.1.28 Q Dehydratase small subunit
PIMLPMKJ_00130 9.6e-124 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
PIMLPMKJ_00131 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
PIMLPMKJ_00132 2.7e-134 pduB E BMC
PIMLPMKJ_00133 6.2e-42 pduA_4 CQ BMC
PIMLPMKJ_00134 8.7e-193 K helix_turn_helix, arabinose operon control protein
PIMLPMKJ_00135 8.9e-145 eutJ E Hsp70 protein
PIMLPMKJ_00136 1.7e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PIMLPMKJ_00137 3e-146
PIMLPMKJ_00138 1.2e-149 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PIMLPMKJ_00139 2.7e-173 S AI-2E family transporter
PIMLPMKJ_00140 2e-132 XK27_07210 6.1.1.6 S B3 4 domain
PIMLPMKJ_00141 1.9e-77 yybA 2.3.1.57 K Transcriptional regulator
PIMLPMKJ_00142 6.7e-90 M1-874 K Domain of unknown function (DUF1836)
PIMLPMKJ_00143 6.3e-88 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
PIMLPMKJ_00144 1.5e-147 ypdB V (ABC) transporter
PIMLPMKJ_00145 6.8e-240 yhdP S Transporter associated domain
PIMLPMKJ_00146 1.2e-82 nrdI F Belongs to the NrdI family
PIMLPMKJ_00147 2.1e-73 S 3-demethylubiquinone-9 3-methyltransferase
PIMLPMKJ_00148 8e-192 yeaN P Transporter, major facilitator family protein
PIMLPMKJ_00149 6.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PIMLPMKJ_00150 1.2e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PIMLPMKJ_00151 8.8e-38
PIMLPMKJ_00152 0.0 lacS G Transporter
PIMLPMKJ_00153 4.7e-79 uspA T universal stress protein
PIMLPMKJ_00154 2.1e-79 K AsnC family
PIMLPMKJ_00155 1.5e-231 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIMLPMKJ_00156 2.1e-90 dedA 3.1.3.1 S SNARE associated Golgi protein
PIMLPMKJ_00157 1.8e-181 galR K Transcriptional regulator
PIMLPMKJ_00158 1.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PIMLPMKJ_00159 5.1e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIMLPMKJ_00160 1.3e-171 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PIMLPMKJ_00161 4.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
PIMLPMKJ_00162 1.2e-91 yxkA S Phosphatidylethanolamine-binding protein
PIMLPMKJ_00163 3.4e-35
PIMLPMKJ_00164 6.5e-51
PIMLPMKJ_00165 1.1e-201
PIMLPMKJ_00166 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIMLPMKJ_00167 4e-136 pnuC H nicotinamide mononucleotide transporter
PIMLPMKJ_00168 6.8e-153 ytbE 1.1.1.346 S Aldo keto reductase
PIMLPMKJ_00169 1.3e-122 K response regulator
PIMLPMKJ_00170 2.2e-179 T PhoQ Sensor
PIMLPMKJ_00171 4.6e-132 macB2 V ABC transporter, ATP-binding protein
PIMLPMKJ_00172 0.0 ysaB V FtsX-like permease family
PIMLPMKJ_00173 8.7e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PIMLPMKJ_00174 1e-141 L PFAM transposase IS116 IS110 IS902
PIMLPMKJ_00175 1.8e-162 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PIMLPMKJ_00176 4.4e-52 K helix_turn_helix, mercury resistance
PIMLPMKJ_00177 5.4e-49 L PFAM transposase IS200-family protein
PIMLPMKJ_00178 4e-153 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PIMLPMKJ_00179 1.5e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PIMLPMKJ_00180 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PIMLPMKJ_00181 2.1e-160 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PIMLPMKJ_00182 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIMLPMKJ_00183 4.6e-62 S integral membrane protein
PIMLPMKJ_00184 5.1e-168 ykoT GT2 M Glycosyl transferase family 2
PIMLPMKJ_00185 7.1e-72 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PIMLPMKJ_00186 1e-34
PIMLPMKJ_00187 2.8e-74 S Acyltransferase family
PIMLPMKJ_00188 1.1e-79 glfT1 1.1.1.133 S Glycosyltransferase like family 2
PIMLPMKJ_00189 2e-66 S Glycosyltransferase like family
PIMLPMKJ_00190 5.8e-76 rgpB GT2 M Glycosyl transferase family 2
PIMLPMKJ_00191 3e-28 M biosynthesis protein
PIMLPMKJ_00192 2.2e-88 cps3F
PIMLPMKJ_00193 9.5e-77 M transferase activity, transferring glycosyl groups
PIMLPMKJ_00194 3.6e-210 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PIMLPMKJ_00195 2.3e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
PIMLPMKJ_00196 0.0 ganB 3.2.1.89 G arabinogalactan
PIMLPMKJ_00197 6.1e-25
PIMLPMKJ_00198 0.0 G Peptidase_C39 like family
PIMLPMKJ_00199 2.4e-289 clcA P chloride
PIMLPMKJ_00200 1.8e-34 secG U Preprotein translocase
PIMLPMKJ_00201 3.1e-144 est 3.1.1.1 S Serine aminopeptidase, S33
PIMLPMKJ_00202 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PIMLPMKJ_00203 4.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PIMLPMKJ_00204 1e-102 yxjI
PIMLPMKJ_00205 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PIMLPMKJ_00206 5.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PIMLPMKJ_00207 2.5e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PIMLPMKJ_00208 3.7e-85 K Acetyltransferase (GNAT) domain
PIMLPMKJ_00209 7.1e-74 S PAS domain
PIMLPMKJ_00210 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
PIMLPMKJ_00211 1.5e-166 murB 1.3.1.98 M Cell wall formation
PIMLPMKJ_00212 2.7e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIMLPMKJ_00213 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PIMLPMKJ_00214 3.7e-249 fucP G Major Facilitator Superfamily
PIMLPMKJ_00215 4.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIMLPMKJ_00216 1.2e-123 ybbR S YbbR-like protein
PIMLPMKJ_00217 3.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PIMLPMKJ_00218 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PIMLPMKJ_00219 4.8e-51
PIMLPMKJ_00220 0.0 oatA I Acyltransferase
PIMLPMKJ_00221 2.5e-77 K Transcriptional regulator
PIMLPMKJ_00222 1.6e-143 XK27_02985 S Cof-like hydrolase
PIMLPMKJ_00223 9e-78 lytE M Lysin motif
PIMLPMKJ_00225 1.5e-132 K response regulator
PIMLPMKJ_00226 2.2e-271 yclK 2.7.13.3 T Histidine kinase
PIMLPMKJ_00227 1.4e-153 glcU U sugar transport
PIMLPMKJ_00228 3.8e-100 lacA 2.3.1.79 S Transferase hexapeptide repeat
PIMLPMKJ_00229 7.7e-263 pgi 5.3.1.9 G Belongs to the GPI family
PIMLPMKJ_00230 2.1e-26
PIMLPMKJ_00232 3.4e-08 xylB 2.7.1.17 G Belongs to the FGGY kinase family
PIMLPMKJ_00233 1.2e-154 KT YcbB domain
PIMLPMKJ_00234 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PIMLPMKJ_00235 1.6e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
PIMLPMKJ_00236 3.9e-162 EG EamA-like transporter family
PIMLPMKJ_00237 6.1e-100 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PIMLPMKJ_00238 8.4e-39 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PIMLPMKJ_00239 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PIMLPMKJ_00240 0.0 copA 3.6.3.54 P P-type ATPase
PIMLPMKJ_00241 1.8e-86
PIMLPMKJ_00243 5.7e-55
PIMLPMKJ_00244 2.1e-25 yjcE P Sodium proton antiporter
PIMLPMKJ_00246 5.3e-84
PIMLPMKJ_00247 0.0 M domain protein
PIMLPMKJ_00248 4.9e-20
PIMLPMKJ_00249 3.2e-181 ampC V Beta-lactamase
PIMLPMKJ_00250 3.5e-238 arcA 3.5.3.6 E Arginine
PIMLPMKJ_00251 3.6e-79 argR K Regulates arginine biosynthesis genes
PIMLPMKJ_00252 3.9e-257 E Arginine ornithine antiporter
PIMLPMKJ_00253 5.5e-216 arcD U Amino acid permease
PIMLPMKJ_00254 7.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
PIMLPMKJ_00255 2.2e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
PIMLPMKJ_00256 1.7e-107 tdk 2.7.1.21 F thymidine kinase
PIMLPMKJ_00257 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PIMLPMKJ_00258 3.9e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PIMLPMKJ_00259 5.7e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PIMLPMKJ_00260 1.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PIMLPMKJ_00261 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PIMLPMKJ_00262 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIMLPMKJ_00263 1.3e-188 yibE S overlaps another CDS with the same product name
PIMLPMKJ_00264 2.6e-130 yibF S overlaps another CDS with the same product name
PIMLPMKJ_00265 1.9e-231 pyrP F Permease
PIMLPMKJ_00266 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
PIMLPMKJ_00267 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIMLPMKJ_00268 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PIMLPMKJ_00269 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIMLPMKJ_00270 8.9e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PIMLPMKJ_00271 7.2e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PIMLPMKJ_00272 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PIMLPMKJ_00273 1.7e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PIMLPMKJ_00274 1.3e-33 ywzB S Protein of unknown function (DUF1146)
PIMLPMKJ_00275 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIMLPMKJ_00276 5.5e-178 mbl D Cell shape determining protein MreB Mrl
PIMLPMKJ_00277 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PIMLPMKJ_00278 1e-31 S Protein of unknown function (DUF2969)
PIMLPMKJ_00279 5.4e-220 rodA D Belongs to the SEDS family
PIMLPMKJ_00280 7.4e-46 gcvH E glycine cleavage
PIMLPMKJ_00283 1e-257 S Uncharacterized protein conserved in bacteria (DUF2252)
PIMLPMKJ_00284 3.5e-288 L PFAM plasmid pRiA4b ORF-3 family protein
PIMLPMKJ_00285 1.4e-203 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
PIMLPMKJ_00286 1.2e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIMLPMKJ_00287 5.3e-156 mleR K LysR family
PIMLPMKJ_00288 2.6e-302 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PIMLPMKJ_00289 2.4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PIMLPMKJ_00290 2.6e-266 frdC 1.3.5.4 C FAD binding domain
PIMLPMKJ_00291 1.7e-252 yflS P Sodium:sulfate symporter transmembrane region
PIMLPMKJ_00292 7.4e-158 mleR K LysR family
PIMLPMKJ_00293 4e-251 yjjP S Putative threonine/serine exporter
PIMLPMKJ_00294 4.7e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
PIMLPMKJ_00295 4.8e-266 emrY EGP Major facilitator Superfamily
PIMLPMKJ_00296 5.9e-180 I Alpha beta
PIMLPMKJ_00297 5.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PIMLPMKJ_00298 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIMLPMKJ_00300 2.8e-157 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PIMLPMKJ_00301 7.6e-116 S Domain of unknown function (DUF4811)
PIMLPMKJ_00302 4.1e-265 lmrB EGP Major facilitator Superfamily
PIMLPMKJ_00303 1.7e-70 merR K MerR HTH family regulatory protein
PIMLPMKJ_00304 1.6e-55
PIMLPMKJ_00305 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIMLPMKJ_00306 1.6e-216 S CAAX protease self-immunity
PIMLPMKJ_00307 1.4e-108 glnP P ABC transporter permease
PIMLPMKJ_00308 9.3e-110 gluC P ABC transporter permease
PIMLPMKJ_00309 2.2e-151 glnH ET ABC transporter
PIMLPMKJ_00310 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PIMLPMKJ_00311 5.5e-83 usp1 T Belongs to the universal stress protein A family
PIMLPMKJ_00312 7.6e-110 S VIT family
PIMLPMKJ_00313 2.3e-114 S membrane
PIMLPMKJ_00314 1.9e-164 czcD P cation diffusion facilitator family transporter
PIMLPMKJ_00315 1.6e-123 sirR K iron dependent repressor
PIMLPMKJ_00316 1e-30 cspC K Cold shock protein
PIMLPMKJ_00317 8.9e-128 thrE S Putative threonine/serine exporter
PIMLPMKJ_00318 1e-81 S Threonine/Serine exporter, ThrE
PIMLPMKJ_00319 6.8e-119 lssY 3.6.1.27 I phosphatase
PIMLPMKJ_00320 4.3e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
PIMLPMKJ_00321 2.3e-276 lysP E amino acid
PIMLPMKJ_00322 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PIMLPMKJ_00328 1.1e-175 S Hydrolases of the alpha beta superfamily
PIMLPMKJ_00329 8e-196 adhP 1.1.1.1 C alcohol dehydrogenase
PIMLPMKJ_00330 4.4e-77 ctsR K Belongs to the CtsR family
PIMLPMKJ_00331 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PIMLPMKJ_00332 1e-110 K Bacterial regulatory proteins, tetR family
PIMLPMKJ_00333 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIMLPMKJ_00334 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIMLPMKJ_00335 6.1e-200 ykiI
PIMLPMKJ_00336 4.4e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PIMLPMKJ_00337 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PIMLPMKJ_00338 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PIMLPMKJ_00339 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PIMLPMKJ_00340 4.6e-233 L Transposase
PIMLPMKJ_00341 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PIMLPMKJ_00342 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PIMLPMKJ_00343 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
PIMLPMKJ_00344 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PIMLPMKJ_00345 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PIMLPMKJ_00346 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PIMLPMKJ_00347 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PIMLPMKJ_00348 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PIMLPMKJ_00349 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PIMLPMKJ_00350 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
PIMLPMKJ_00351 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PIMLPMKJ_00352 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PIMLPMKJ_00353 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PIMLPMKJ_00354 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PIMLPMKJ_00355 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIMLPMKJ_00356 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PIMLPMKJ_00357 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PIMLPMKJ_00358 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PIMLPMKJ_00359 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PIMLPMKJ_00360 2.9e-24 rpmD J Ribosomal protein L30
PIMLPMKJ_00361 8.9e-64 rplO J Binds to the 23S rRNA
PIMLPMKJ_00362 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PIMLPMKJ_00363 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PIMLPMKJ_00364 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PIMLPMKJ_00365 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PIMLPMKJ_00366 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PIMLPMKJ_00367 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIMLPMKJ_00368 1.5e-62 rplQ J Ribosomal protein L17
PIMLPMKJ_00369 3.6e-138 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIMLPMKJ_00370 2.7e-144 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIMLPMKJ_00371 5.9e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIMLPMKJ_00372 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PIMLPMKJ_00373 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PIMLPMKJ_00374 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PIMLPMKJ_00375 2.7e-140 IQ reductase
PIMLPMKJ_00376 5.2e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
PIMLPMKJ_00377 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PIMLPMKJ_00378 2.7e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PIMLPMKJ_00379 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PIMLPMKJ_00380 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PIMLPMKJ_00381 4.7e-202 camS S sex pheromone
PIMLPMKJ_00382 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIMLPMKJ_00383 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PIMLPMKJ_00384 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIMLPMKJ_00385 6.7e-187 yegS 2.7.1.107 G Lipid kinase
PIMLPMKJ_00386 3.2e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIMLPMKJ_00387 4.8e-76 L ATPase involved in DNA repair
PIMLPMKJ_00388 1.1e-84 K Bacterial regulatory proteins, tetR family
PIMLPMKJ_00389 1.6e-71 1.6.5.2 S NADPH-dependent FMN reductase
PIMLPMKJ_00390 3e-173 L Plasmid pRiA4b ORF-3-like protein
PIMLPMKJ_00391 1.5e-43 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
PIMLPMKJ_00392 3.8e-43
PIMLPMKJ_00393 1.6e-93 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PIMLPMKJ_00394 1.9e-234 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
PIMLPMKJ_00395 6.2e-86
PIMLPMKJ_00396 2.4e-113 pnb C nitroreductase
PIMLPMKJ_00397 3.6e-60 ogt 2.1.1.63 L Methyltransferase
PIMLPMKJ_00398 1.9e-148 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
PIMLPMKJ_00399 4e-67 S Protein of unknown function (DUF3021)
PIMLPMKJ_00400 7.3e-74 K LytTr DNA-binding domain
PIMLPMKJ_00401 1.6e-20
PIMLPMKJ_00402 5.5e-193 yhjX P Major Facilitator Superfamily
PIMLPMKJ_00403 9.3e-119 ybhL S Belongs to the BI1 family
PIMLPMKJ_00404 1.2e-74 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
PIMLPMKJ_00405 6.1e-188 S Protein of unknown function (DUF3114)
PIMLPMKJ_00406 1.2e-293 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PIMLPMKJ_00407 1.9e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PIMLPMKJ_00408 6e-100 yvdD 3.2.2.10 S Belongs to the LOG family
PIMLPMKJ_00409 9.1e-62 S Domain of unknown function (DUF4828)
PIMLPMKJ_00410 2.2e-190 mocA S Oxidoreductase
PIMLPMKJ_00411 5e-227 yfmL L DEAD DEAH box helicase
PIMLPMKJ_00413 4.6e-205 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIMLPMKJ_00414 1.2e-55
PIMLPMKJ_00415 1.5e-74 gtcA S Teichoic acid glycosylation protein
PIMLPMKJ_00416 3e-78 fld C Flavodoxin
PIMLPMKJ_00417 1.1e-166 map 3.4.11.18 E Methionine Aminopeptidase
PIMLPMKJ_00418 3.3e-219 arcT 2.6.1.1 E Aminotransferase
PIMLPMKJ_00419 2.5e-256 E Arginine ornithine antiporter
PIMLPMKJ_00420 2.6e-280 yjeM E Amino Acid
PIMLPMKJ_00421 3.9e-146 yihY S Belongs to the UPF0761 family
PIMLPMKJ_00422 5e-34 S Protein of unknown function (DUF2922)
PIMLPMKJ_00423 5.5e-30
PIMLPMKJ_00424 2.9e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
PIMLPMKJ_00425 3e-147 cps1D M Domain of unknown function (DUF4422)
PIMLPMKJ_00426 1.8e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PIMLPMKJ_00427 5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
PIMLPMKJ_00428 0.0 2.7.7.6 M Peptidase family M23
PIMLPMKJ_00440 0.0 UW LPXTG-motif cell wall anchor domain protein
PIMLPMKJ_00441 0.0 UW LPXTG-motif cell wall anchor domain protein
PIMLPMKJ_00443 1.8e-153 metQ_4 P Belongs to the nlpA lipoprotein family
PIMLPMKJ_00444 5.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PIMLPMKJ_00445 1.8e-122 O Zinc-dependent metalloprotease
PIMLPMKJ_00446 7.1e-115 S Membrane
PIMLPMKJ_00447 1.4e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PIMLPMKJ_00448 1.2e-60 S Domain of unknown function (DUF4767)
PIMLPMKJ_00449 4.3e-13
PIMLPMKJ_00450 2e-94 wecD3 K PFAM GCN5-related N-acetyltransferase
PIMLPMKJ_00451 6.8e-78
PIMLPMKJ_00452 2.7e-106 M Lysin motif
PIMLPMKJ_00453 9.3e-193 EGP Major facilitator Superfamily
PIMLPMKJ_00454 4.8e-97 ywlG S Belongs to the UPF0340 family
PIMLPMKJ_00455 2.9e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PIMLPMKJ_00456 1.3e-136 pnuC H nicotinamide mononucleotide transporter
PIMLPMKJ_00457 4.3e-127 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
PIMLPMKJ_00458 2.6e-99 crp_2 K Cyclic nucleotide-binding domain
PIMLPMKJ_00459 2.4e-28 S PFAM Archaeal ATPase
PIMLPMKJ_00460 2e-155 spoU 2.1.1.185 J Methyltransferase
PIMLPMKJ_00461 4.6e-75 L Belongs to the 'phage' integrase family
PIMLPMKJ_00463 6.8e-55
PIMLPMKJ_00464 1.7e-58 D ftsk spoiiie
PIMLPMKJ_00466 1.1e-19
PIMLPMKJ_00467 0.0 L helicase
PIMLPMKJ_00468 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PIMLPMKJ_00470 9.3e-220 S cog cog1373
PIMLPMKJ_00471 2.4e-175 coaA 2.7.1.33 F Pantothenic acid kinase
PIMLPMKJ_00472 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIMLPMKJ_00473 4.4e-13 EG EamA-like transporter family
PIMLPMKJ_00474 2.2e-99 EG EamA-like transporter family
PIMLPMKJ_00475 3.2e-253 nox C NADH oxidase
PIMLPMKJ_00476 4.5e-239 nox C NADH oxidase
PIMLPMKJ_00477 0.0 helD 3.6.4.12 L DNA helicase
PIMLPMKJ_00478 3.5e-112 dedA S SNARE associated Golgi protein
PIMLPMKJ_00479 1e-124 3.1.3.73 G phosphoglycerate mutase
PIMLPMKJ_00480 3.1e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PIMLPMKJ_00481 5.4e-49 L PFAM transposase IS200-family protein
PIMLPMKJ_00482 2.1e-244 yifK E Amino acid permease
PIMLPMKJ_00483 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIMLPMKJ_00484 2.9e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIMLPMKJ_00485 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PIMLPMKJ_00486 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIMLPMKJ_00488 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PIMLPMKJ_00489 2.6e-239 glpT G Major Facilitator Superfamily
PIMLPMKJ_00490 8.8e-15
PIMLPMKJ_00492 2e-169 whiA K May be required for sporulation
PIMLPMKJ_00493 3.7e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PIMLPMKJ_00494 5.2e-156 rapZ S Displays ATPase and GTPase activities
PIMLPMKJ_00495 2.7e-244 steT E amino acid
PIMLPMKJ_00496 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PIMLPMKJ_00497 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PIMLPMKJ_00498 6.9e-14
PIMLPMKJ_00499 1.6e-114 yfbR S HD containing hydrolase-like enzyme
PIMLPMKJ_00500 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PIMLPMKJ_00501 2.3e-87 ykhA 3.1.2.20 I Thioesterase superfamily
PIMLPMKJ_00502 1.6e-18 aatB ET PFAM extracellular solute-binding protein, family 3
PIMLPMKJ_00503 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIMLPMKJ_00504 1.5e-157 lutA C Cysteine-rich domain
PIMLPMKJ_00505 1.4e-286 lutB C 4Fe-4S dicluster domain
PIMLPMKJ_00506 4.3e-135 yrjD S LUD domain
PIMLPMKJ_00507 2.6e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PIMLPMKJ_00508 2.2e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PIMLPMKJ_00509 8.5e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PIMLPMKJ_00510 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PIMLPMKJ_00511 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PIMLPMKJ_00512 5.3e-32 KT PspC domain protein
PIMLPMKJ_00513 1.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PIMLPMKJ_00514 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIMLPMKJ_00515 7.2e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PIMLPMKJ_00516 9.5e-113 comFC S Competence protein
PIMLPMKJ_00517 8.6e-251 comFA L Helicase C-terminal domain protein
PIMLPMKJ_00518 1.2e-106 yvyE 3.4.13.9 S YigZ family
PIMLPMKJ_00519 4e-73 EGP Major facilitator Superfamily
PIMLPMKJ_00520 2.4e-132 EGP Major facilitator Superfamily
PIMLPMKJ_00521 5e-64 rmaI K Transcriptional regulator
PIMLPMKJ_00522 2.7e-39
PIMLPMKJ_00523 0.0 ydaO E amino acid
PIMLPMKJ_00524 5.3e-303 ybeC E amino acid
PIMLPMKJ_00525 1.6e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PIMLPMKJ_00526 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PIMLPMKJ_00527 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIMLPMKJ_00528 8.9e-289 uup S ABC transporter, ATP-binding protein
PIMLPMKJ_00529 3.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIMLPMKJ_00530 1.2e-224 mtnE 2.6.1.83 E Aminotransferase
PIMLPMKJ_00531 5.4e-136 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PIMLPMKJ_00532 4.9e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PIMLPMKJ_00533 3.3e-220 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PIMLPMKJ_00534 4.5e-127 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIMLPMKJ_00535 2.6e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PIMLPMKJ_00536 8.1e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PIMLPMKJ_00537 8e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PIMLPMKJ_00538 2.7e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PIMLPMKJ_00539 4.2e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PIMLPMKJ_00540 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PIMLPMKJ_00541 2.3e-276 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PIMLPMKJ_00542 2.5e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
PIMLPMKJ_00543 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PIMLPMKJ_00544 2.9e-57 yabA L Involved in initiation control of chromosome replication
PIMLPMKJ_00545 4.5e-183 holB 2.7.7.7 L DNA polymerase III
PIMLPMKJ_00546 7.6e-52 yaaQ S Cyclic-di-AMP receptor
PIMLPMKJ_00547 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PIMLPMKJ_00548 1.1e-37 S Protein of unknown function (DUF2508)
PIMLPMKJ_00549 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PIMLPMKJ_00550 1.2e-46 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PIMLPMKJ_00551 2.4e-296 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIMLPMKJ_00552 4.2e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PIMLPMKJ_00553 3.4e-35 nrdH O Glutaredoxin
PIMLPMKJ_00554 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIMLPMKJ_00555 6.5e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIMLPMKJ_00556 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PIMLPMKJ_00557 2.7e-132 S Putative adhesin
PIMLPMKJ_00558 1.2e-82 XK27_06920 S Protein of unknown function (DUF1700)
PIMLPMKJ_00559 1.5e-55 K transcriptional regulator PadR family
PIMLPMKJ_00560 1.9e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIMLPMKJ_00562 7.7e-48
PIMLPMKJ_00563 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PIMLPMKJ_00564 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PIMLPMKJ_00565 2e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIMLPMKJ_00566 5.5e-242 M Glycosyl transferase family group 2
PIMLPMKJ_00568 1.1e-223 aadAT EK Aminotransferase, class I
PIMLPMKJ_00569 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PIMLPMKJ_00570 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PIMLPMKJ_00571 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
PIMLPMKJ_00572 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PIMLPMKJ_00573 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PIMLPMKJ_00574 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIMLPMKJ_00575 6.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PIMLPMKJ_00576 4.8e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PIMLPMKJ_00577 1.8e-201 yacL S domain protein
PIMLPMKJ_00578 5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PIMLPMKJ_00579 4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PIMLPMKJ_00580 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
PIMLPMKJ_00581 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PIMLPMKJ_00582 2.1e-265 pepC 3.4.22.40 E Peptidase C1-like family
PIMLPMKJ_00583 1.3e-137 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PIMLPMKJ_00584 8.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PIMLPMKJ_00585 1.4e-119 tcyB E ABC transporter
PIMLPMKJ_00586 1.7e-210 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PIMLPMKJ_00587 2.3e-167 I alpha/beta hydrolase fold
PIMLPMKJ_00588 1.9e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIMLPMKJ_00589 0.0 S Bacterial membrane protein, YfhO
PIMLPMKJ_00590 3.6e-182 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PIMLPMKJ_00591 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PIMLPMKJ_00593 6.4e-81 ydcK S Belongs to the SprT family
PIMLPMKJ_00594 0.0 yhgF K Tex-like protein N-terminal domain protein
PIMLPMKJ_00595 1.8e-150 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PIMLPMKJ_00596 3.8e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIMLPMKJ_00597 5.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
PIMLPMKJ_00598 1.2e-129 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PIMLPMKJ_00599 2.5e-300 aspT P Predicted Permease Membrane Region
PIMLPMKJ_00600 7.2e-248 EGP Major facilitator Superfamily
PIMLPMKJ_00601 6.5e-111
PIMLPMKJ_00604 2.2e-151 yjjH S Calcineurin-like phosphoesterase
PIMLPMKJ_00605 1e-263 dtpT U amino acid peptide transporter
PIMLPMKJ_00606 1.1e-18
PIMLPMKJ_00612 2.8e-193 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PIMLPMKJ_00613 1e-223 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PIMLPMKJ_00614 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIMLPMKJ_00615 2.9e-154 asp3 S Accessory Sec secretory system ASP3
PIMLPMKJ_00616 3.6e-213 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
PIMLPMKJ_00617 9e-196 M transferase activity, transferring glycosyl groups
PIMLPMKJ_00618 1.3e-157 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
PIMLPMKJ_00619 3.7e-161 nss M transferase activity, transferring glycosyl groups
PIMLPMKJ_00620 0.0 M LPXTG-motif cell wall anchor domain protein
PIMLPMKJ_00621 0.0 trxB2 1.8.1.9 C Thioredoxin domain
PIMLPMKJ_00622 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
PIMLPMKJ_00623 5.9e-139 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PIMLPMKJ_00624 5.6e-118 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PIMLPMKJ_00626 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIMLPMKJ_00627 6.7e-164 T Calcineurin-like phosphoesterase superfamily domain
PIMLPMKJ_00628 3.5e-222 mdtG EGP Major facilitator Superfamily
PIMLPMKJ_00629 1.7e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PIMLPMKJ_00630 1.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PIMLPMKJ_00631 2.4e-173 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PIMLPMKJ_00632 1.1e-119 lacZ 3.2.1.23 G -beta-galactosidase
PIMLPMKJ_00633 9.5e-83
PIMLPMKJ_00634 2.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
PIMLPMKJ_00635 2.5e-33
PIMLPMKJ_00636 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PIMLPMKJ_00637 6.4e-260 yfnA E amino acid
PIMLPMKJ_00638 6.4e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PIMLPMKJ_00639 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PIMLPMKJ_00640 6.6e-38 ylqC S Belongs to the UPF0109 family
PIMLPMKJ_00641 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PIMLPMKJ_00642 1.5e-248 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PIMLPMKJ_00643 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PIMLPMKJ_00644 7.8e-179 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PIMLPMKJ_00645 0.0 smc D Required for chromosome condensation and partitioning
PIMLPMKJ_00646 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PIMLPMKJ_00647 1.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIMLPMKJ_00648 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PIMLPMKJ_00649 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PIMLPMKJ_00650 0.0 yloV S DAK2 domain fusion protein YloV
PIMLPMKJ_00651 4.7e-58 asp S Asp23 family, cell envelope-related function
PIMLPMKJ_00652 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PIMLPMKJ_00653 5e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
PIMLPMKJ_00654 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PIMLPMKJ_00655 2.1e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PIMLPMKJ_00656 0.0 KLT serine threonine protein kinase
PIMLPMKJ_00657 7.2e-130 stp 3.1.3.16 T phosphatase
PIMLPMKJ_00658 2.5e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PIMLPMKJ_00659 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PIMLPMKJ_00660 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIMLPMKJ_00661 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PIMLPMKJ_00662 8.6e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PIMLPMKJ_00663 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PIMLPMKJ_00664 1.2e-52
PIMLPMKJ_00665 3.6e-262 recN L May be involved in recombinational repair of damaged DNA
PIMLPMKJ_00666 1.6e-76 argR K Regulates arginine biosynthesis genes
PIMLPMKJ_00667 4.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PIMLPMKJ_00668 1.4e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PIMLPMKJ_00669 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIMLPMKJ_00670 1.1e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIMLPMKJ_00671 2.3e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIMLPMKJ_00672 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PIMLPMKJ_00673 8.4e-70 yqhY S Asp23 family, cell envelope-related function
PIMLPMKJ_00674 1.6e-107 J 2'-5' RNA ligase superfamily
PIMLPMKJ_00675 1.8e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PIMLPMKJ_00676 1.1e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PIMLPMKJ_00677 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PIMLPMKJ_00678 6.2e-54 ysxB J Cysteine protease Prp
PIMLPMKJ_00679 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
PIMLPMKJ_00680 4.4e-112 K Transcriptional regulator
PIMLPMKJ_00683 5.1e-87 dut S Protein conserved in bacteria
PIMLPMKJ_00684 1.7e-182
PIMLPMKJ_00685 2.8e-149
PIMLPMKJ_00686 1.7e-51 S Iron-sulfur cluster assembly protein
PIMLPMKJ_00687 2.3e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIMLPMKJ_00688 1.4e-93 M Glycosyl hydrolases family 25
PIMLPMKJ_00689 2.2e-35 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PIMLPMKJ_00690 7.4e-55 S Bacteriophage holin family
PIMLPMKJ_00693 1.6e-31 S Domain of unknown function (DUF2479)
PIMLPMKJ_00696 2.4e-61 M Prophage endopeptidase tail
PIMLPMKJ_00697 2.4e-70 S Phage tail protein
PIMLPMKJ_00698 4.2e-116 S peptidoglycan catabolic process
PIMLPMKJ_00699 3.5e-34 S Bacteriophage Gp15 protein
PIMLPMKJ_00700 1.9e-08
PIMLPMKJ_00701 2.5e-39 N domain, Protein
PIMLPMKJ_00702 2.2e-16 S Minor capsid protein from bacteriophage
PIMLPMKJ_00703 4.6e-12 S Minor capsid protein
PIMLPMKJ_00704 4.4e-29 S Minor capsid protein
PIMLPMKJ_00705 8.3e-14
PIMLPMKJ_00706 8e-99
PIMLPMKJ_00707 3.1e-24 S Phage minor structural protein GP20
PIMLPMKJ_00709 1.1e-92 S Phage minor capsid protein 2
PIMLPMKJ_00710 3.9e-127 S Phage portal protein, SPP1 Gp6-like
PIMLPMKJ_00711 8.5e-134 L Phage terminase, large subunit
PIMLPMKJ_00712 1.8e-92 xtmA L Terminase small subunit
PIMLPMKJ_00714 7.2e-28
PIMLPMKJ_00715 9.9e-23
PIMLPMKJ_00720 8.8e-81 Q DNA (cytosine-5-)-methyltransferase activity
PIMLPMKJ_00726 1.4e-106 L DnaD domain protein
PIMLPMKJ_00729 4.7e-15
PIMLPMKJ_00734 2.6e-13
PIMLPMKJ_00735 4.9e-40 ps115 K Helix-turn-helix XRE-family like proteins
PIMLPMKJ_00736 5.1e-19 E Zn peptidase
PIMLPMKJ_00737 2e-30 S Domain of unknown function (DUF4352)
PIMLPMKJ_00738 5.7e-27
PIMLPMKJ_00739 2.4e-90 L Belongs to the 'phage' integrase family
PIMLPMKJ_00740 9.7e-83 S Fic/DOC family
PIMLPMKJ_00742 3.9e-12
PIMLPMKJ_00743 8e-216 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PIMLPMKJ_00744 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PIMLPMKJ_00745 8.9e-264 glnA 6.3.1.2 E glutamine synthetase
PIMLPMKJ_00746 1.9e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PIMLPMKJ_00747 5.9e-22 S Protein of unknown function (DUF3042)
PIMLPMKJ_00748 3.4e-67 yqhL P Rhodanese-like protein
PIMLPMKJ_00749 5.6e-183 glk 2.7.1.2 G Glucokinase
PIMLPMKJ_00750 3.1e-23 yqgQ S Bacterial protein of unknown function (DUF910)
PIMLPMKJ_00751 2e-107 gluP 3.4.21.105 S Peptidase, S54 family
PIMLPMKJ_00752 2.9e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PIMLPMKJ_00753 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PIMLPMKJ_00754 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PIMLPMKJ_00755 0.0 S membrane
PIMLPMKJ_00756 1.8e-68 yneR S Belongs to the HesB IscA family
PIMLPMKJ_00757 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIMLPMKJ_00758 1.4e-116 udk 2.7.1.48 F Cytidine monophosphokinase
PIMLPMKJ_00759 1.1e-113 rlpA M PFAM NLP P60 protein
PIMLPMKJ_00760 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIMLPMKJ_00761 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PIMLPMKJ_00762 6.7e-59 yodB K Transcriptional regulator, HxlR family
PIMLPMKJ_00763 1.2e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PIMLPMKJ_00764 7e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIMLPMKJ_00765 8.8e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PIMLPMKJ_00766 9.4e-167 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIMLPMKJ_00767 9.6e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PIMLPMKJ_00768 2.9e-230 V MatE
PIMLPMKJ_00769 1.3e-266 yjeM E Amino Acid
PIMLPMKJ_00770 8.3e-279 arlS 2.7.13.3 T Histidine kinase
PIMLPMKJ_00771 1.5e-121 K response regulator
PIMLPMKJ_00772 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PIMLPMKJ_00773 2.9e-99 yceD S Uncharacterized ACR, COG1399
PIMLPMKJ_00774 1.2e-205 ylbM S Belongs to the UPF0348 family
PIMLPMKJ_00775 4.3e-135 yqeM Q Methyltransferase
PIMLPMKJ_00776 8.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PIMLPMKJ_00777 3.6e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PIMLPMKJ_00778 2.5e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PIMLPMKJ_00779 1.9e-47 yhbY J RNA-binding protein
PIMLPMKJ_00780 3.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
PIMLPMKJ_00781 9.1e-95 yqeG S HAD phosphatase, family IIIA
PIMLPMKJ_00782 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PIMLPMKJ_00783 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PIMLPMKJ_00784 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PIMLPMKJ_00785 8.1e-171 dnaI L Primosomal protein DnaI
PIMLPMKJ_00786 3e-222 dnaB L replication initiation and membrane attachment
PIMLPMKJ_00787 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PIMLPMKJ_00788 2.7e-95 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PIMLPMKJ_00789 1.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PIMLPMKJ_00790 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PIMLPMKJ_00791 7.8e-115 yoaK S Protein of unknown function (DUF1275)
PIMLPMKJ_00792 4.2e-119 ybhL S Belongs to the BI1 family
PIMLPMKJ_00793 3.8e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PIMLPMKJ_00794 1.6e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PIMLPMKJ_00795 9.1e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
PIMLPMKJ_00796 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIMLPMKJ_00797 2.5e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PIMLPMKJ_00798 1.8e-56 ytzB S Small secreted protein
PIMLPMKJ_00799 1.3e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
PIMLPMKJ_00800 1.4e-178 iolS C Aldo keto reductase
PIMLPMKJ_00801 3.4e-248 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PIMLPMKJ_00802 0.0 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
PIMLPMKJ_00803 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PIMLPMKJ_00804 7.3e-217 ecsB U ABC transporter
PIMLPMKJ_00805 1.6e-134 ecsA V ABC transporter, ATP-binding protein
PIMLPMKJ_00806 2e-76 hit FG histidine triad
PIMLPMKJ_00808 4.5e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIMLPMKJ_00809 0.0 L AAA domain
PIMLPMKJ_00810 9.2e-212 yhaO L Ser Thr phosphatase family protein
PIMLPMKJ_00811 4.7e-37 yheA S Belongs to the UPF0342 family
PIMLPMKJ_00812 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PIMLPMKJ_00813 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PIMLPMKJ_00814 4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PIMLPMKJ_00815 1.4e-163 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PIMLPMKJ_00816 5.4e-49 L PFAM transposase IS200-family protein
PIMLPMKJ_00817 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
PIMLPMKJ_00818 1.1e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIMLPMKJ_00819 8.8e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
PIMLPMKJ_00820 1.7e-224 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PIMLPMKJ_00821 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIMLPMKJ_00822 2.7e-39 ptsH G phosphocarrier protein HPR
PIMLPMKJ_00823 7e-26
PIMLPMKJ_00824 0.0 clpE O Belongs to the ClpA ClpB family
PIMLPMKJ_00825 2.4e-99 S Pfam:DUF3816
PIMLPMKJ_00826 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PIMLPMKJ_00827 3.8e-109
PIMLPMKJ_00828 7.5e-155 V ABC transporter, ATP-binding protein
PIMLPMKJ_00829 2.7e-64 gntR1 K Transcriptional regulator, GntR family
PIMLPMKJ_00830 0.0 S Peptidase, M23
PIMLPMKJ_00831 0.0 M NlpC/P60 family
PIMLPMKJ_00832 9.6e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PIMLPMKJ_00833 2.6e-208 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PIMLPMKJ_00834 2.2e-162 yueF S AI-2E family transporter
PIMLPMKJ_00835 0.0 csd1 3.5.1.28 G domain, Protein
PIMLPMKJ_00837 6.4e-17 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIMLPMKJ_00838 1.4e-22 UW Tetratricopeptide repeat
PIMLPMKJ_00839 2.1e-271 pipD E Dipeptidase
PIMLPMKJ_00840 4.7e-292 yjbQ P TrkA C-terminal domain protein
PIMLPMKJ_00841 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PIMLPMKJ_00842 2.1e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PIMLPMKJ_00843 4.9e-90
PIMLPMKJ_00844 5.1e-37
PIMLPMKJ_00845 9.3e-101 K DNA-templated transcription, initiation
PIMLPMKJ_00846 1.6e-121
PIMLPMKJ_00847 1.1e-65 K Transcriptional regulator, HxlR family
PIMLPMKJ_00848 8.3e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PIMLPMKJ_00849 1.8e-140 epsB M biosynthesis protein
PIMLPMKJ_00850 5.2e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PIMLPMKJ_00851 1e-103 rfbP M Bacterial sugar transferase
PIMLPMKJ_00852 1.1e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
PIMLPMKJ_00853 6.6e-55 pssE S Glycosyltransferase family 28 C-terminal domain
PIMLPMKJ_00854 3.3e-142 GT2,GT4 S Haloacid dehalogenase-like hydrolase
PIMLPMKJ_00855 2.8e-53 M Glycosyl transferases group 1
PIMLPMKJ_00856 9.6e-85 epsJ GT2 S Glycosyltransferase like family 2
PIMLPMKJ_00857 7.8e-35
PIMLPMKJ_00858 1.5e-28 2.3.1.30 E serine acetyltransferase
PIMLPMKJ_00859 1e-67 2.7.8.12 M Glycosyltransferase sugar-binding region containing DXD motif
PIMLPMKJ_00860 2.1e-106 cps2J S Polysaccharide biosynthesis protein
PIMLPMKJ_00861 3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PIMLPMKJ_00862 7.1e-124 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PIMLPMKJ_00863 6.7e-87 L Psort location Cytoplasmic, score
PIMLPMKJ_00864 5.1e-98 busR K UTRA
PIMLPMKJ_00865 5.8e-167 yegU O ADP-ribosylglycohydrolase
PIMLPMKJ_00866 5.4e-240 F Belongs to the purine-cytosine permease (2.A.39) family
PIMLPMKJ_00867 5.7e-118 G Belongs to the carbohydrate kinase PfkB family
PIMLPMKJ_00869 1.6e-25
PIMLPMKJ_00870 9.3e-43 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PIMLPMKJ_00872 3e-225 V ATPase associated with various cellular activities
PIMLPMKJ_00873 3.9e-46
PIMLPMKJ_00874 2.7e-45
PIMLPMKJ_00875 1.3e-165 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PIMLPMKJ_00876 1e-249 mmuP E amino acid
PIMLPMKJ_00878 9.5e-42 K Psort location Cytoplasmic, score
PIMLPMKJ_00880 1e-142 ywqE 3.1.3.48 GM PHP domain protein
PIMLPMKJ_00881 4.7e-176 M Glycosyl hydrolases family 25
PIMLPMKJ_00882 4.4e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PIMLPMKJ_00883 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PIMLPMKJ_00884 9.5e-92 L nuclease
PIMLPMKJ_00885 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
PIMLPMKJ_00886 2.1e-70
PIMLPMKJ_00887 1.1e-101 fic D Fic/DOC family
PIMLPMKJ_00888 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PIMLPMKJ_00889 1.9e-44 3.1.3.73 G Belongs to the phosphoglycerate mutase family
PIMLPMKJ_00890 2.2e-93 3.1.3.73 G Belongs to the phosphoglycerate mutase family
PIMLPMKJ_00891 0.0
PIMLPMKJ_00892 0.0
PIMLPMKJ_00893 8.4e-26
PIMLPMKJ_00894 5.4e-49 L PFAM transposase IS200-family protein
PIMLPMKJ_00895 2e-264 glnP P ABC transporter
PIMLPMKJ_00896 5.1e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PIMLPMKJ_00897 1e-219 cycA E Amino acid permease
PIMLPMKJ_00898 1.3e-218 nupG F Nucleoside transporter
PIMLPMKJ_00899 1.7e-170 rihC 3.2.2.1 F Nucleoside
PIMLPMKJ_00900 5.1e-159 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PIMLPMKJ_00901 6.4e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PIMLPMKJ_00902 1.5e-148 noc K Belongs to the ParB family
PIMLPMKJ_00903 1.8e-139 soj D Sporulation initiation inhibitor
PIMLPMKJ_00904 3.9e-151 spo0J K Belongs to the ParB family
PIMLPMKJ_00905 1.7e-30 yyzM S Bacterial protein of unknown function (DUF951)
PIMLPMKJ_00906 3.7e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PIMLPMKJ_00907 3.8e-134 XK27_01040 S Protein of unknown function (DUF1129)
PIMLPMKJ_00908 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PIMLPMKJ_00909 1e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PIMLPMKJ_00910 7.6e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
PIMLPMKJ_00911 4e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PIMLPMKJ_00912 1.1e-170 deoR K sugar-binding domain protein
PIMLPMKJ_00913 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIMLPMKJ_00914 3.8e-125 K response regulator
PIMLPMKJ_00915 1.4e-201 hpk31 2.7.13.3 T Histidine kinase
PIMLPMKJ_00916 2.7e-139 azlC E AzlC protein
PIMLPMKJ_00917 8.1e-52 azlD S branched-chain amino acid
PIMLPMKJ_00918 5.1e-135 K LysR substrate binding domain
PIMLPMKJ_00919 1.9e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PIMLPMKJ_00920 6.9e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PIMLPMKJ_00921 3.2e-92 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIMLPMKJ_00922 2.5e-65 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIMLPMKJ_00923 1.3e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PIMLPMKJ_00924 2.8e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PIMLPMKJ_00925 9e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
PIMLPMKJ_00926 9.7e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PIMLPMKJ_00927 3.1e-171 K AI-2E family transporter
PIMLPMKJ_00928 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PIMLPMKJ_00929 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PIMLPMKJ_00930 3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PIMLPMKJ_00931 4e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PIMLPMKJ_00932 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PIMLPMKJ_00933 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIMLPMKJ_00934 1.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIMLPMKJ_00935 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIMLPMKJ_00936 9e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PIMLPMKJ_00937 2.3e-190 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PIMLPMKJ_00938 5.2e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PIMLPMKJ_00939 2.1e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PIMLPMKJ_00940 1.1e-242 purD 6.3.4.13 F Belongs to the GARS family
PIMLPMKJ_00941 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIMLPMKJ_00942 5.7e-149
PIMLPMKJ_00943 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIMLPMKJ_00944 5.4e-49 L PFAM transposase IS200-family protein
PIMLPMKJ_00945 9.3e-209 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PIMLPMKJ_00946 3.1e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIMLPMKJ_00948 8.1e-87
PIMLPMKJ_00949 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PIMLPMKJ_00950 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PIMLPMKJ_00951 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PIMLPMKJ_00952 1.6e-174 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PIMLPMKJ_00953 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PIMLPMKJ_00954 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PIMLPMKJ_00955 4.9e-08
PIMLPMKJ_00956 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PIMLPMKJ_00957 4.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
PIMLPMKJ_00958 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PIMLPMKJ_00959 3.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PIMLPMKJ_00960 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PIMLPMKJ_00961 4.3e-161 S Tetratricopeptide repeat
PIMLPMKJ_00962 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIMLPMKJ_00963 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PIMLPMKJ_00964 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
PIMLPMKJ_00965 2.4e-144 holA 2.7.7.7 L DNA polymerase III delta subunit
PIMLPMKJ_00966 0.0 comEC S Competence protein ComEC
PIMLPMKJ_00967 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
PIMLPMKJ_00968 4.2e-78 comEA L Competence protein ComEA
PIMLPMKJ_00969 3e-18
PIMLPMKJ_00970 5.6e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PIMLPMKJ_00971 2.5e-74
PIMLPMKJ_00972 2.2e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PIMLPMKJ_00973 4.2e-128 ponA V Beta-lactamase enzyme family
PIMLPMKJ_00974 1.1e-283 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
PIMLPMKJ_00975 4.1e-215 uhpT EGP Major facilitator Superfamily
PIMLPMKJ_00976 2.1e-252 ytjP 3.5.1.18 E Dipeptidase
PIMLPMKJ_00977 7.7e-272 arcD S C4-dicarboxylate anaerobic carrier
PIMLPMKJ_00978 1.5e-177 yfeX P Peroxidase
PIMLPMKJ_00979 1.5e-163 lsa S ABC transporter
PIMLPMKJ_00980 4.8e-131 I alpha/beta hydrolase fold
PIMLPMKJ_00981 8.9e-179 MA20_14895 S Conserved hypothetical protein 698
PIMLPMKJ_00982 1.3e-93 S NADPH-dependent FMN reductase
PIMLPMKJ_00983 1.6e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PIMLPMKJ_00984 1.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PIMLPMKJ_00985 2.6e-231 mntH P H( )-stimulated, divalent metal cation uptake system
PIMLPMKJ_00986 4.8e-75 Q Methyltransferase
PIMLPMKJ_00987 6.9e-116 ktrA P domain protein
PIMLPMKJ_00988 3e-235 ktrB P Potassium uptake protein
PIMLPMKJ_00989 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
PIMLPMKJ_00990 5.3e-128 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PIMLPMKJ_00991 4.3e-124 phoU P Plays a role in the regulation of phosphate uptake
PIMLPMKJ_00992 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIMLPMKJ_00993 1.2e-152 pstA P Phosphate transport system permease protein PstA
PIMLPMKJ_00994 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
PIMLPMKJ_00995 1.9e-158 pstS P Phosphate
PIMLPMKJ_00996 3.5e-134 K Transcriptional regulatory protein, C-terminal domain protein
PIMLPMKJ_00997 2.3e-136 cbiO P ABC transporter
PIMLPMKJ_00998 3.8e-135 P Cobalt transport protein
PIMLPMKJ_00999 8.2e-185 nikMN P PDGLE domain
PIMLPMKJ_01000 6.9e-74 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIMLPMKJ_01001 4.9e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIMLPMKJ_01002 8.2e-162 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PIMLPMKJ_01003 1.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PIMLPMKJ_01004 2.1e-131 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PIMLPMKJ_01005 3.3e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PIMLPMKJ_01006 0.0 ureC 3.5.1.5 E Amidohydrolase family
PIMLPMKJ_01007 2.9e-63 ureB 3.5.1.5 E Urease beta subunit
PIMLPMKJ_01008 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
PIMLPMKJ_01009 1.9e-97 ureI S AmiS/UreI family transporter
PIMLPMKJ_01010 1.7e-221 P ammonium transporter
PIMLPMKJ_01011 2.8e-16 K Transcriptional regulator, HxlR family
PIMLPMKJ_01012 7.1e-181
PIMLPMKJ_01013 1.2e-97 2.3.1.128 K acetyltransferase
PIMLPMKJ_01014 2.8e-142 manA 5.3.1.8 G mannose-6-phosphate isomerase
PIMLPMKJ_01016 5.6e-165
PIMLPMKJ_01017 2.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIMLPMKJ_01018 5.4e-182 S Phosphotransferase system, EIIC
PIMLPMKJ_01019 2.8e-132 infB UW LPXTG-motif cell wall anchor domain protein
PIMLPMKJ_01020 8e-109 dedA S SNARE-like domain protein
PIMLPMKJ_01021 3.6e-101 S Protein of unknown function (DUF1461)
PIMLPMKJ_01022 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PIMLPMKJ_01023 2.3e-93 yutD S Protein of unknown function (DUF1027)
PIMLPMKJ_01024 3.2e-112 S Calcineurin-like phosphoesterase
PIMLPMKJ_01025 2.3e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIMLPMKJ_01026 2.2e-152 ytxK 2.1.1.72 L N-6 DNA Methylase
PIMLPMKJ_01028 1.2e-68
PIMLPMKJ_01029 7.1e-41
PIMLPMKJ_01030 2e-76 NU general secretion pathway protein
PIMLPMKJ_01031 1.3e-45 comGC U competence protein ComGC
PIMLPMKJ_01032 1.3e-174 comGB NU type II secretion system
PIMLPMKJ_01033 1e-176 comGA NU Type II IV secretion system protein
PIMLPMKJ_01034 5.9e-132 yebC K Transcriptional regulatory protein
PIMLPMKJ_01035 1.4e-129
PIMLPMKJ_01036 4.2e-181 ccpA K catabolite control protein A
PIMLPMKJ_01037 1.8e-209 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PIMLPMKJ_01038 1.5e-29
PIMLPMKJ_01039 6.1e-36 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIMLPMKJ_01040 1.1e-145 ykuT M mechanosensitive ion channel
PIMLPMKJ_01041 1.5e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PIMLPMKJ_01042 3.9e-75 ykuL S (CBS) domain
PIMLPMKJ_01043 1.8e-90 S Phosphoesterase
PIMLPMKJ_01044 6.5e-102 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PIMLPMKJ_01045 9.2e-139 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PIMLPMKJ_01046 2.3e-96 yslB S Protein of unknown function (DUF2507)
PIMLPMKJ_01047 5.1e-53 trxA O Belongs to the thioredoxin family
PIMLPMKJ_01048 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIMLPMKJ_01049 7.8e-86 cvpA S Colicin V production protein
PIMLPMKJ_01050 1.4e-47 yrzB S Belongs to the UPF0473 family
PIMLPMKJ_01051 7.9e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PIMLPMKJ_01052 7.7e-42 yrzL S Belongs to the UPF0297 family
PIMLPMKJ_01053 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PIMLPMKJ_01054 9.2e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PIMLPMKJ_01055 2.7e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PIMLPMKJ_01056 4e-30 yajC U Preprotein translocase
PIMLPMKJ_01057 5.3e-182 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PIMLPMKJ_01058 2.2e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PIMLPMKJ_01059 9.6e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PIMLPMKJ_01060 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PIMLPMKJ_01061 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PIMLPMKJ_01062 1.8e-207 rny S Endoribonuclease that initiates mRNA decay
PIMLPMKJ_01063 2.7e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIMLPMKJ_01064 4.5e-217 cinA 3.5.1.42 S Belongs to the CinA family
PIMLPMKJ_01065 2.1e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIMLPMKJ_01066 6.3e-132 ymfM S Helix-turn-helix domain
PIMLPMKJ_01067 1.4e-245 ymfH S Peptidase M16
PIMLPMKJ_01068 2.9e-224 ymfF S Peptidase M16 inactive domain protein
PIMLPMKJ_01069 5.8e-160 aatB ET ABC transporter substrate-binding protein
PIMLPMKJ_01070 2.3e-116 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PIMLPMKJ_01071 3.2e-102 glnP P ABC transporter permease
PIMLPMKJ_01072 3.3e-92 mreD M rod shape-determining protein MreD
PIMLPMKJ_01073 3.2e-150 mreC M Involved in formation and maintenance of cell shape
PIMLPMKJ_01074 1.7e-179 mreB D cell shape determining protein MreB
PIMLPMKJ_01075 6.8e-121 radC L DNA repair protein
PIMLPMKJ_01076 2.7e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PIMLPMKJ_01077 1.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
PIMLPMKJ_01078 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PIMLPMKJ_01079 8.2e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PIMLPMKJ_01080 2.4e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PIMLPMKJ_01081 1.2e-271 cydA 1.10.3.14 C ubiquinol oxidase
PIMLPMKJ_01082 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PIMLPMKJ_01083 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PIMLPMKJ_01084 3.3e-214 iscS2 2.8.1.7 E Aminotransferase class V
PIMLPMKJ_01085 5.9e-236 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PIMLPMKJ_01086 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PIMLPMKJ_01087 2.5e-234 pbuG S permease
PIMLPMKJ_01088 1.1e-269 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PIMLPMKJ_01089 1e-183 gadC E amino acid
PIMLPMKJ_01090 1.9e-96 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PIMLPMKJ_01091 4.3e-258 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PIMLPMKJ_01092 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
PIMLPMKJ_01093 3.7e-134 S Belongs to the UPF0246 family
PIMLPMKJ_01094 7.9e-137 S Membrane
PIMLPMKJ_01095 8.9e-74 4.4.1.5 E Glyoxalase
PIMLPMKJ_01096 2e-21
PIMLPMKJ_01097 2.5e-83 yueI S Protein of unknown function (DUF1694)
PIMLPMKJ_01098 1.1e-234 rarA L recombination factor protein RarA
PIMLPMKJ_01099 1.7e-45
PIMLPMKJ_01100 4.3e-83 usp6 T universal stress protein
PIMLPMKJ_01101 3.8e-204 araR K Transcriptional regulator
PIMLPMKJ_01102 4e-153 ytbE 1.1.1.346 S Aldo keto reductase
PIMLPMKJ_01103 5.2e-175 yfdV S Membrane transport protein
PIMLPMKJ_01104 5.5e-78 maa 2.3.1.79 S Maltose O-acetyltransferase
PIMLPMKJ_01105 4.8e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PIMLPMKJ_01106 4.9e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PIMLPMKJ_01107 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
PIMLPMKJ_01108 1.8e-259 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PIMLPMKJ_01109 1e-143 K transcriptional regulator, ArsR family
PIMLPMKJ_01110 1.3e-174 abf G Belongs to the glycosyl hydrolase 43 family
PIMLPMKJ_01111 1e-216 lacY G Oligosaccharide H symporter
PIMLPMKJ_01112 3.7e-146 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PIMLPMKJ_01113 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PIMLPMKJ_01114 2.8e-132 infB UW LPXTG-motif cell wall anchor domain protein
PIMLPMKJ_01115 7.9e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PIMLPMKJ_01116 0.0 yhcA V ABC transporter, ATP-binding protein
PIMLPMKJ_01117 2.2e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PIMLPMKJ_01118 1.6e-167 hrtB V ABC transporter permease
PIMLPMKJ_01119 1.8e-84 ygfC K transcriptional regulator (TetR family)
PIMLPMKJ_01120 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
PIMLPMKJ_01121 1.8e-287 mntH P H( )-stimulated, divalent metal cation uptake system
PIMLPMKJ_01122 9.5e-23
PIMLPMKJ_01123 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIMLPMKJ_01125 5.1e-221 yxiO S Vacuole effluxer Atg22 like
PIMLPMKJ_01126 4.4e-255 npp S type I phosphodiesterase nucleotide pyrophosphatase
PIMLPMKJ_01127 7.1e-240 E amino acid
PIMLPMKJ_01128 4.4e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIMLPMKJ_01129 9.1e-217 yxjG_1 E methionine synthase, vitamin-B12 independent
PIMLPMKJ_01130 4.6e-08 S Cytochrome B5
PIMLPMKJ_01131 1.4e-26 S Cytochrome B5
PIMLPMKJ_01132 4.5e-71 elaA S Gnat family
PIMLPMKJ_01133 4.1e-121 GM NmrA-like family
PIMLPMKJ_01134 1.4e-50 hxlR K Transcriptional regulator, HxlR family
PIMLPMKJ_01135 2.6e-106 XK27_02070 S Nitroreductase family
PIMLPMKJ_01136 1.9e-80 K Transcriptional regulator, HxlR family
PIMLPMKJ_01137 2e-231
PIMLPMKJ_01138 3e-207 EGP Major facilitator Superfamily
PIMLPMKJ_01139 9.8e-255 pepC 3.4.22.40 E aminopeptidase
PIMLPMKJ_01140 8.4e-111 ylbE GM NAD dependent epimerase dehydratase family protein
PIMLPMKJ_01141 0.0 pepN 3.4.11.2 E aminopeptidase
PIMLPMKJ_01142 9.3e-48 K Transcriptional regulator
PIMLPMKJ_01143 1.8e-88 folT S ECF transporter, substrate-specific component
PIMLPMKJ_01144 1.5e-30 yjaB_1 K Acetyltransferase (GNAT) domain
PIMLPMKJ_01145 8.4e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
PIMLPMKJ_01146 6.6e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PIMLPMKJ_01147 7.5e-113 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
PIMLPMKJ_01148 1.6e-189 2.7.7.65 T GGDEF domain
PIMLPMKJ_01149 5e-87
PIMLPMKJ_01150 1.3e-251 pgaC GT2 M Glycosyl transferase
PIMLPMKJ_01151 2.3e-129 T EAL domain
PIMLPMKJ_01152 1e-122 yfeJ 6.3.5.2 F glutamine amidotransferase
PIMLPMKJ_01153 5.2e-100 qorB 1.6.5.2 GM NmrA-like family
PIMLPMKJ_01154 1.8e-159 akr5f 1.1.1.346 S reductase
PIMLPMKJ_01155 7.4e-142 K Transcriptional regulator
PIMLPMKJ_01156 1.4e-181 ansA 3.5.1.1 EJ L-asparaginase, type I
PIMLPMKJ_01157 4.1e-28 XK27_04080 H Riboflavin biosynthesis protein RibD
PIMLPMKJ_01158 2.8e-20 XK27_04080 H Riboflavin biosynthesis protein RibD
PIMLPMKJ_01159 7.9e-156 ypuA S Protein of unknown function (DUF1002)
PIMLPMKJ_01160 1.2e-227 aadAT EK Aminotransferase, class I
PIMLPMKJ_01161 1.1e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PIMLPMKJ_01162 6e-154 tesE Q hydratase
PIMLPMKJ_01163 9.9e-139 S Alpha beta hydrolase
PIMLPMKJ_01164 7.8e-86 lacA S transferase hexapeptide repeat
PIMLPMKJ_01165 1.2e-152 K Transcriptional regulator
PIMLPMKJ_01166 1e-84 C Flavodoxin
PIMLPMKJ_01167 5.8e-163 S Oxidoreductase, aldo keto reductase family protein
PIMLPMKJ_01168 1.2e-48 K helix_turn_helix, mercury resistance
PIMLPMKJ_01169 7e-89 rocF 3.5.3.1, 3.5.3.11 E Arginase family
PIMLPMKJ_01170 5.8e-167 1.1.1.1 C nadph quinone reductase
PIMLPMKJ_01171 6.6e-56 yphJ 4.1.1.44 S decarboxylase
PIMLPMKJ_01172 1.3e-20 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
PIMLPMKJ_01173 6.7e-115 P nitric oxide dioxygenase activity
PIMLPMKJ_01174 1.8e-108 S Peptidase propeptide and YPEB domain
PIMLPMKJ_01175 1.9e-213 T GHKL domain
PIMLPMKJ_01176 4.6e-115 T Transcriptional regulatory protein, C terminal
PIMLPMKJ_01177 1.2e-115 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
PIMLPMKJ_01182 3.4e-212 2.7.13.3 T GHKL domain
PIMLPMKJ_01183 1.6e-119 K LytTr DNA-binding domain
PIMLPMKJ_01184 1.2e-88 XK27_08850 J Aminoacyl-tRNA editing domain
PIMLPMKJ_01185 1.5e-65 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIMLPMKJ_01186 1.3e-195 V Beta-lactamase
PIMLPMKJ_01187 3.7e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PIMLPMKJ_01188 2.3e-114 yhiD S MgtC family
PIMLPMKJ_01189 5.5e-50 azlD E Branched-chain amino acid transport
PIMLPMKJ_01190 1.4e-119 azlC E azaleucine resistance protein AzlC
PIMLPMKJ_01191 2e-242 K Aminotransferase class I and II
PIMLPMKJ_01192 9.7e-294 S amidohydrolase
PIMLPMKJ_01193 3.6e-101 S Alpha/beta hydrolase of unknown function (DUF915)
PIMLPMKJ_01195 7.5e-163 S reductase
PIMLPMKJ_01196 1.3e-85 2.3.1.183 M Acetyltransferase GNAT family
PIMLPMKJ_01197 2.5e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PIMLPMKJ_01198 3.2e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
PIMLPMKJ_01199 9.9e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PIMLPMKJ_01200 0.0 asnB 6.3.5.4 E Asparagine synthase
PIMLPMKJ_01201 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PIMLPMKJ_01202 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PIMLPMKJ_01203 1.4e-128 jag S R3H domain protein
PIMLPMKJ_01204 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIMLPMKJ_01205 4.6e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PIMLPMKJ_01206 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PIMLPMKJ_01207 3.2e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PIMLPMKJ_01208 3e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PIMLPMKJ_01209 1.7e-34 yaaA S S4 domain protein YaaA
PIMLPMKJ_01210 3.9e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PIMLPMKJ_01211 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIMLPMKJ_01212 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIMLPMKJ_01213 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
PIMLPMKJ_01214 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIMLPMKJ_01215 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PIMLPMKJ_01224 3.3e-87 2.3.1.128 K Acetyltransferase (GNAT) domain
PIMLPMKJ_01225 1e-230 lmrB EGP Major facilitator Superfamily
PIMLPMKJ_01226 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PIMLPMKJ_01227 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PIMLPMKJ_01228 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
PIMLPMKJ_01229 4.8e-42 lytE M LysM domain protein
PIMLPMKJ_01230 0.0 oppD EP Psort location Cytoplasmic, score
PIMLPMKJ_01231 1.2e-94 lytE M LysM domain protein
PIMLPMKJ_01232 2.3e-147 xth 3.1.11.2 L exodeoxyribonuclease III
PIMLPMKJ_01233 5.2e-234 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PIMLPMKJ_01234 1.2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
PIMLPMKJ_01235 2.9e-151 yeaE S Aldo keto
PIMLPMKJ_01236 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
PIMLPMKJ_01237 3.5e-269 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PIMLPMKJ_01238 3.1e-72 S Psort location Cytoplasmic, score
PIMLPMKJ_01239 3.3e-81 S Short repeat of unknown function (DUF308)
PIMLPMKJ_01240 1e-23
PIMLPMKJ_01241 1.1e-101 V VanZ like family
PIMLPMKJ_01242 5.7e-59 cycA E Amino acid permease
PIMLPMKJ_01243 3.7e-15 cycA E Amino acid permease
PIMLPMKJ_01244 3.2e-84 perR P Belongs to the Fur family
PIMLPMKJ_01245 1.2e-253 EGP Major facilitator Superfamily
PIMLPMKJ_01246 6e-94 tag 3.2.2.20 L glycosylase
PIMLPMKJ_01247 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PIMLPMKJ_01248 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PIMLPMKJ_01249 2.4e-40
PIMLPMKJ_01250 9.2e-303 ytgP S Polysaccharide biosynthesis protein
PIMLPMKJ_01251 4.5e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PIMLPMKJ_01252 3.3e-269 pepV 3.5.1.18 E dipeptidase PepV
PIMLPMKJ_01253 3.6e-85 uspA T Belongs to the universal stress protein A family
PIMLPMKJ_01254 1.4e-171 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIMLPMKJ_01255 3.6e-114 dck 2.7.1.74 F deoxynucleoside kinase
PIMLPMKJ_01256 2.1e-111
PIMLPMKJ_01257 1.4e-184 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
PIMLPMKJ_01258 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIMLPMKJ_01259 3.1e-31
PIMLPMKJ_01260 3.6e-109 S CAAX protease self-immunity
PIMLPMKJ_01261 1.9e-43
PIMLPMKJ_01265 1.7e-19 L Phage regulatory protein
PIMLPMKJ_01266 1.2e-12
PIMLPMKJ_01267 1e-10 K sequence-specific DNA binding
PIMLPMKJ_01268 1.3e-26 L nuclease
PIMLPMKJ_01269 3.4e-23
PIMLPMKJ_01270 1.5e-42 S Domain of unknown function DUF1829
PIMLPMKJ_01271 4.9e-69
PIMLPMKJ_01272 1e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PIMLPMKJ_01273 1.9e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PIMLPMKJ_01274 1.8e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PIMLPMKJ_01275 6.3e-219 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PIMLPMKJ_01276 9.1e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PIMLPMKJ_01277 6.4e-210 folP 2.5.1.15 H dihydropteroate synthase
PIMLPMKJ_01278 2e-42
PIMLPMKJ_01279 3.3e-40
PIMLPMKJ_01281 1.5e-86 infB UW LPXTG-motif cell wall anchor domain protein
PIMLPMKJ_01282 0.0 fhaB M Rib/alpha-like repeat
PIMLPMKJ_01283 2.2e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PIMLPMKJ_01284 8.5e-200 XK27_09615 S reductase
PIMLPMKJ_01285 1e-99 nqr 1.5.1.36 S reductase
PIMLPMKJ_01286 9e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIMLPMKJ_01287 2.9e-174 K Transcriptional regulator, LacI family
PIMLPMKJ_01288 3e-259 G Major Facilitator
PIMLPMKJ_01289 1.2e-266 G Major Facilitator
PIMLPMKJ_01290 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
PIMLPMKJ_01291 1.2e-261 M domain protein
PIMLPMKJ_01292 7.7e-264 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PIMLPMKJ_01293 1.7e-266 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PIMLPMKJ_01294 2.2e-72
PIMLPMKJ_01295 2.8e-238 L Transposase
PIMLPMKJ_01296 2.3e-108 K Transcriptional regulator, TetR family
PIMLPMKJ_01298 1.3e-80 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIMLPMKJ_01299 3.4e-82
PIMLPMKJ_01300 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PIMLPMKJ_01301 1.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIMLPMKJ_01302 1.3e-259 nox C NADH oxidase
PIMLPMKJ_01303 8.6e-87 hmpT S ECF-type riboflavin transporter, S component
PIMLPMKJ_01304 2.5e-311 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
PIMLPMKJ_01305 7.1e-16 yvgN C Aldo keto reductase
PIMLPMKJ_01306 1.2e-134 puuD S peptidase C26
PIMLPMKJ_01307 7.1e-253 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PIMLPMKJ_01308 1.3e-205 yfeO P Voltage gated chloride channel
PIMLPMKJ_01309 2e-217 sptS 2.7.13.3 T Histidine kinase
PIMLPMKJ_01310 1.1e-113 K response regulator
PIMLPMKJ_01311 8.2e-87 2.7.6.5 T Region found in RelA / SpoT proteins
PIMLPMKJ_01312 1e-52
PIMLPMKJ_01313 1.9e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PIMLPMKJ_01314 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PIMLPMKJ_01315 1.1e-256 malT G Major Facilitator
PIMLPMKJ_01316 1.5e-206 phbA 2.3.1.9 I Belongs to the thiolase family
PIMLPMKJ_01317 1.2e-169 malR K Transcriptional regulator, LacI family
PIMLPMKJ_01318 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PIMLPMKJ_01319 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PIMLPMKJ_01320 9.7e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIMLPMKJ_01321 1.1e-101 wecD3 K PFAM GCN5-related N-acetyltransferase
PIMLPMKJ_01323 2.4e-182 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PIMLPMKJ_01324 0.0 clpL O associated with various cellular activities
PIMLPMKJ_01325 2.7e-32
PIMLPMKJ_01326 1.3e-213 patA 2.6.1.1 E Aminotransferase
PIMLPMKJ_01327 2.4e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIMLPMKJ_01328 5e-75 osmC O OsmC-like protein
PIMLPMKJ_01330 1.1e-242 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PIMLPMKJ_01333 1.1e-128 K LytTr DNA-binding domain
PIMLPMKJ_01334 2.1e-164 2.7.13.3 T GHKL domain
PIMLPMKJ_01336 1.5e-258 S Putative peptidoglycan binding domain
PIMLPMKJ_01337 6.3e-37
PIMLPMKJ_01339 1.3e-213 bacI V MacB-like periplasmic core domain
PIMLPMKJ_01340 2.4e-127 V ABC transporter
PIMLPMKJ_01341 1.3e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PIMLPMKJ_01342 6.8e-251 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PIMLPMKJ_01343 9.6e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIMLPMKJ_01344 2.7e-148 E Glyoxalase-like domain
PIMLPMKJ_01345 7.5e-155 glcU U sugar transport
PIMLPMKJ_01346 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
PIMLPMKJ_01347 3.2e-95 S reductase
PIMLPMKJ_01349 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PIMLPMKJ_01350 6.6e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PIMLPMKJ_01351 1.3e-216 htrA 3.4.21.107 O serine protease
PIMLPMKJ_01352 1.7e-153 vicX 3.1.26.11 S domain protein
PIMLPMKJ_01353 4.6e-149 yycI S YycH protein
PIMLPMKJ_01354 7.3e-247 yycH S YycH protein
PIMLPMKJ_01355 0.0 vicK 2.7.13.3 T Histidine kinase
PIMLPMKJ_01356 3.1e-130 K response regulator
PIMLPMKJ_01358 5.2e-309 lmrA 3.6.3.44 V ABC transporter
PIMLPMKJ_01359 8.3e-73 K helix_turn_helix multiple antibiotic resistance protein
PIMLPMKJ_01361 1.8e-123 Z012_01130 S Fic/DOC family
PIMLPMKJ_01362 2.2e-99 K DNA-binding helix-turn-helix protein
PIMLPMKJ_01363 3.8e-162 S Polyphosphate nucleotide phosphotransferase, PPK2 family
PIMLPMKJ_01364 2.5e-58
PIMLPMKJ_01365 2.2e-205 yttB EGP Major facilitator Superfamily
PIMLPMKJ_01366 6.9e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PIMLPMKJ_01367 2e-74 rplI J Binds to the 23S rRNA
PIMLPMKJ_01368 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PIMLPMKJ_01369 5.4e-49 L PFAM transposase IS200-family protein
PIMLPMKJ_01370 3e-307 cadA P P-type ATPase
PIMLPMKJ_01371 1.6e-203 5.4.2.7 G Metalloenzyme superfamily
PIMLPMKJ_01373 2.5e-155 1.6.5.2 GM NAD(P)H-binding
PIMLPMKJ_01374 1.7e-73 K Transcriptional regulator
PIMLPMKJ_01375 3.3e-161 proX M ABC transporter, substrate-binding protein, QAT family
PIMLPMKJ_01376 5.9e-104 proWZ P ABC transporter permease
PIMLPMKJ_01377 3.3e-138 proV E ABC transporter, ATP-binding protein
PIMLPMKJ_01378 1.3e-98 proW P ABC transporter, permease protein
PIMLPMKJ_01379 2.4e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PIMLPMKJ_01380 1.5e-247 clcA P chloride
PIMLPMKJ_01381 1.5e-211 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PIMLPMKJ_01382 1.5e-102 metI P ABC transporter permease
PIMLPMKJ_01383 4e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PIMLPMKJ_01384 2.2e-154 metQ1 P Belongs to the nlpA lipoprotein family
PIMLPMKJ_01385 6.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PIMLPMKJ_01386 2.2e-221 norA EGP Major facilitator Superfamily
PIMLPMKJ_01387 3.3e-43 1.3.5.4 S FMN binding
PIMLPMKJ_01388 7.9e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PIMLPMKJ_01389 3.4e-264 yfnA E amino acid
PIMLPMKJ_01390 1.1e-253 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIMLPMKJ_01392 2.6e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PIMLPMKJ_01393 0.0 helD 3.6.4.12 L DNA helicase
PIMLPMKJ_01394 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
PIMLPMKJ_01395 3.5e-177 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
PIMLPMKJ_01396 3.2e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PIMLPMKJ_01397 3.5e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PIMLPMKJ_01398 1.9e-223 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PIMLPMKJ_01399 5e-176
PIMLPMKJ_01400 3e-130 cobB K SIR2 family
PIMLPMKJ_01402 7.1e-158 yunF F Protein of unknown function DUF72
PIMLPMKJ_01403 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PIMLPMKJ_01404 2.8e-151 tatD L hydrolase, TatD family
PIMLPMKJ_01405 5.5e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PIMLPMKJ_01406 1.3e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PIMLPMKJ_01407 6.8e-37 veg S Biofilm formation stimulator VEG
PIMLPMKJ_01408 5.5e-158 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PIMLPMKJ_01409 5.3e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
PIMLPMKJ_01410 7.7e-123 fhuC P ABC transporter
PIMLPMKJ_01411 1.1e-120 znuB U ABC 3 transport family
PIMLPMKJ_01412 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PIMLPMKJ_01413 2e-239 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PIMLPMKJ_01414 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIMLPMKJ_01415 6.2e-49
PIMLPMKJ_01416 1.3e-145 yxeH S hydrolase
PIMLPMKJ_01417 1.5e-269 ywfO S HD domain protein
PIMLPMKJ_01418 1.5e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
PIMLPMKJ_01419 1e-66 ywiB S Domain of unknown function (DUF1934)
PIMLPMKJ_01420 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PIMLPMKJ_01421 2e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PIMLPMKJ_01422 2.2e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIMLPMKJ_01423 4.6e-41 rpmE2 J Ribosomal protein L31
PIMLPMKJ_01424 8e-233 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIMLPMKJ_01425 1.2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
PIMLPMKJ_01426 1.9e-124 srtA 3.4.22.70 M sortase family
PIMLPMKJ_01427 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PIMLPMKJ_01428 2.1e-159 3.2.1.55 GH51 G Right handed beta helix region
PIMLPMKJ_01429 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIMLPMKJ_01430 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PIMLPMKJ_01431 2.1e-117 pgm3 G Belongs to the phosphoglycerate mutase family
PIMLPMKJ_01432 7.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIMLPMKJ_01433 7e-93 lemA S LemA family
PIMLPMKJ_01434 1.5e-158 htpX O Belongs to the peptidase M48B family
PIMLPMKJ_01435 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PIMLPMKJ_01436 2.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PIMLPMKJ_01437 0.0 sprD D Domain of Unknown Function (DUF1542)
PIMLPMKJ_01438 2.5e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
PIMLPMKJ_01439 1.2e-249 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PIMLPMKJ_01440 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIMLPMKJ_01441 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
PIMLPMKJ_01442 1.5e-291 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIMLPMKJ_01444 6.5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PIMLPMKJ_01445 4.5e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIMLPMKJ_01446 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
PIMLPMKJ_01447 2.6e-250 U Belongs to the purine-cytosine permease (2.A.39) family
PIMLPMKJ_01448 1.5e-241 codA 3.5.4.1 F cytosine deaminase
PIMLPMKJ_01449 2.2e-145 tesE Q hydratase
PIMLPMKJ_01450 1.1e-113 S (CBS) domain
PIMLPMKJ_01451 3.7e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PIMLPMKJ_01452 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PIMLPMKJ_01453 1.4e-38 yabO J S4 domain protein
PIMLPMKJ_01454 5.6e-56 divIC D Septum formation initiator
PIMLPMKJ_01455 9.8e-67 yabR J RNA binding
PIMLPMKJ_01456 3.6e-247 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PIMLPMKJ_01457 2.6e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PIMLPMKJ_01458 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PIMLPMKJ_01459 3e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PIMLPMKJ_01460 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIMLPMKJ_01461 6.1e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PIMLPMKJ_01462 1.9e-84
PIMLPMKJ_01466 2.2e-14 K Cro/C1-type HTH DNA-binding domain
PIMLPMKJ_01467 1.7e-51 ebh D nuclear chromosome segregation
PIMLPMKJ_01469 2e-11 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PIMLPMKJ_01470 8.3e-10 L Resolvase, N terminal domain
PIMLPMKJ_01471 2.1e-76 L Resolvase, N terminal domain
PIMLPMKJ_01472 4.8e-144
PIMLPMKJ_01473 0.0
PIMLPMKJ_01475 6.3e-20
PIMLPMKJ_01476 3.2e-127 L Belongs to the 'phage' integrase family
PIMLPMKJ_01477 7.5e-122 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PIMLPMKJ_01478 5.9e-159 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PIMLPMKJ_01479 1.5e-42 hxlR K Transcriptional regulator, HxlR family
PIMLPMKJ_01480 5.2e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
PIMLPMKJ_01481 9.3e-130 IQ Dehydrogenase reductase
PIMLPMKJ_01482 5.4e-36
PIMLPMKJ_01483 3.1e-113 ywnB S NAD(P)H-binding
PIMLPMKJ_01484 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
PIMLPMKJ_01485 2.7e-250 nhaC C Na H antiporter NhaC
PIMLPMKJ_01486 3.8e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIMLPMKJ_01488 5.7e-100 ydeN S Serine hydrolase
PIMLPMKJ_01489 7.7e-62 psiE S Phosphate-starvation-inducible E
PIMLPMKJ_01490 6.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIMLPMKJ_01492 1.6e-177 S Aldo keto reductase
PIMLPMKJ_01493 2.5e-78 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
PIMLPMKJ_01494 0.0 L Helicase C-terminal domain protein
PIMLPMKJ_01496 4.5e-247 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PIMLPMKJ_01497 3.1e-53 S Sugar efflux transporter for intercellular exchange
PIMLPMKJ_01498 8.2e-122
PIMLPMKJ_01499 3.9e-128 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PIMLPMKJ_01500 2e-18 L hmm pf00665
PIMLPMKJ_01501 2.8e-180 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PIMLPMKJ_01502 4.2e-158 rrmA 2.1.1.187 H Methyltransferase
PIMLPMKJ_01503 1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PIMLPMKJ_01504 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PIMLPMKJ_01505 1.2e-10 S Protein of unknown function (DUF4044)
PIMLPMKJ_01506 1.5e-53
PIMLPMKJ_01507 9.1e-77 mraZ K Belongs to the MraZ family
PIMLPMKJ_01508 8e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PIMLPMKJ_01509 1.5e-56 ftsL D Cell division protein FtsL
PIMLPMKJ_01510 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PIMLPMKJ_01511 2.9e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PIMLPMKJ_01512 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PIMLPMKJ_01513 1.4e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PIMLPMKJ_01514 2.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PIMLPMKJ_01515 4.3e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PIMLPMKJ_01516 5.8e-225 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PIMLPMKJ_01517 2.6e-68 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PIMLPMKJ_01518 4.1e-40 yggT S YGGT family
PIMLPMKJ_01519 9.2e-144 ylmH S S4 domain protein
PIMLPMKJ_01520 1.9e-42 divIVA D DivIVA domain protein
PIMLPMKJ_01521 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PIMLPMKJ_01522 4.2e-32 cspA K Cold shock protein
PIMLPMKJ_01523 1.4e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PIMLPMKJ_01525 8.5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PIMLPMKJ_01526 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
PIMLPMKJ_01527 7.5e-58 XK27_04120 S Putative amino acid metabolism
PIMLPMKJ_01528 1.5e-216 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PIMLPMKJ_01529 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PIMLPMKJ_01530 6.4e-117 S Repeat protein
PIMLPMKJ_01531 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PIMLPMKJ_01532 8.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIMLPMKJ_01533 4.6e-295 UW LPXTG-motif cell wall anchor domain protein
PIMLPMKJ_01534 2.5e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PIMLPMKJ_01535 2e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
PIMLPMKJ_01536 7.9e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PIMLPMKJ_01537 7.2e-71 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PIMLPMKJ_01538 3.7e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PIMLPMKJ_01539 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PIMLPMKJ_01540 2.1e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PIMLPMKJ_01541 2.6e-214 patA 2.6.1.1 E Aminotransferase
PIMLPMKJ_01542 1.7e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PIMLPMKJ_01543 1.2e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PIMLPMKJ_01544 2.2e-57
PIMLPMKJ_01546 4.9e-127 mltD CBM50 M NlpC P60 family protein
PIMLPMKJ_01547 5.7e-29
PIMLPMKJ_01548 1.9e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
PIMLPMKJ_01549 1.7e-31 ykzG S Belongs to the UPF0356 family
PIMLPMKJ_01550 9.7e-80
PIMLPMKJ_01551 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIMLPMKJ_01552 8.8e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PIMLPMKJ_01553 3.1e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PIMLPMKJ_01554 8.7e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIMLPMKJ_01555 5.4e-275 lpdA 1.8.1.4 C Dehydrogenase
PIMLPMKJ_01556 6.7e-47 yktA S Belongs to the UPF0223 family
PIMLPMKJ_01557 4.8e-132 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PIMLPMKJ_01558 0.0 typA T GTP-binding protein TypA
PIMLPMKJ_01559 1.2e-222 ftsW D Belongs to the SEDS family
PIMLPMKJ_01560 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PIMLPMKJ_01561 8.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PIMLPMKJ_01562 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PIMLPMKJ_01563 3.9e-198 ylbL T Belongs to the peptidase S16 family
PIMLPMKJ_01564 5.4e-49 L PFAM transposase IS200-family protein
PIMLPMKJ_01565 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIMLPMKJ_01566 3.4e-195 EGP Major facilitator Superfamily
PIMLPMKJ_01567 9.8e-86 ymdB S Macro domain protein
PIMLPMKJ_01568 3.8e-63 K Helix-turn-helix domain
PIMLPMKJ_01569 1.7e-24
PIMLPMKJ_01570 0.0 pepO 3.4.24.71 O Peptidase family M13
PIMLPMKJ_01571 3.9e-47
PIMLPMKJ_01572 4.5e-236 S Putative metallopeptidase domain
PIMLPMKJ_01573 1.2e-205 3.1.3.1 S associated with various cellular activities
PIMLPMKJ_01574 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PIMLPMKJ_01575 2e-64 yeaO S Protein of unknown function, DUF488
PIMLPMKJ_01577 1.5e-113 yrkL S Flavodoxin-like fold
PIMLPMKJ_01578 8.1e-54
PIMLPMKJ_01581 3.6e-137 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PIMLPMKJ_01582 1.1e-49
PIMLPMKJ_01586 3.6e-13 K Helix-turn-helix domain
PIMLPMKJ_01588 1.9e-200 nrnB S DHHA1 domain
PIMLPMKJ_01589 4.1e-231 S Uncharacterized protein conserved in bacteria (DUF2325)
PIMLPMKJ_01590 3.5e-247 brnQ U Component of the transport system for branched-chain amino acids
PIMLPMKJ_01591 3.7e-105 NU mannosyl-glycoprotein
PIMLPMKJ_01592 1.1e-136 S Putative ABC-transporter type IV
PIMLPMKJ_01593 4.6e-272 S ABC transporter, ATP-binding protein
PIMLPMKJ_01594 1.9e-91 K Helix-turn-helix domain
PIMLPMKJ_01595 1.7e-45
PIMLPMKJ_01596 1.4e-31 WQ51_00220 K Helix-turn-helix domain
PIMLPMKJ_01597 6.9e-102 S Protein of unknown function (DUF3278)
PIMLPMKJ_01598 1.4e-08
PIMLPMKJ_01599 6.6e-73 M PFAM NLP P60 protein
PIMLPMKJ_01600 5.4e-181 ABC-SBP S ABC transporter
PIMLPMKJ_01601 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PIMLPMKJ_01602 1.8e-136 XK27_08845 S ABC transporter, ATP-binding protein
PIMLPMKJ_01603 5.9e-92 P Cadmium resistance transporter
PIMLPMKJ_01604 6.8e-56 K Transcriptional regulator, ArsR family
PIMLPMKJ_01605 5.9e-236 mepA V MATE efflux family protein
PIMLPMKJ_01606 1.8e-69 2.5.1.74 H UbiA prenyltransferase family
PIMLPMKJ_01607 4.4e-52 trxA O Belongs to the thioredoxin family
PIMLPMKJ_01608 3.3e-130 terC P membrane
PIMLPMKJ_01609 1.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PIMLPMKJ_01610 2.2e-168 corA P CorA-like Mg2+ transporter protein
PIMLPMKJ_01611 3.4e-277 pipD E Dipeptidase
PIMLPMKJ_01612 7.8e-236 pbuX F xanthine permease
PIMLPMKJ_01613 6.5e-249 nhaC C Na H antiporter NhaC
PIMLPMKJ_01614 4.2e-281 S C4-dicarboxylate anaerobic carrier
PIMLPMKJ_01615 2.5e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
PIMLPMKJ_01616 2.7e-39
PIMLPMKJ_01617 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIMLPMKJ_01618 4.2e-206 gldA 1.1.1.6 C dehydrogenase
PIMLPMKJ_01619 2.7e-120 S Alpha beta hydrolase
PIMLPMKJ_01620 1.5e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PIMLPMKJ_01621 1.2e-92
PIMLPMKJ_01623 6.4e-122 yciB M ErfK YbiS YcfS YnhG
PIMLPMKJ_01624 5.6e-15
PIMLPMKJ_01625 2.4e-259 S Putative peptidoglycan binding domain
PIMLPMKJ_01626 1.9e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PIMLPMKJ_01627 1e-87
PIMLPMKJ_01628 2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
PIMLPMKJ_01629 2.9e-213 yttB EGP Major facilitator Superfamily
PIMLPMKJ_01630 3.2e-107
PIMLPMKJ_01631 1e-24
PIMLPMKJ_01632 1.1e-172 scrR K Transcriptional regulator, LacI family
PIMLPMKJ_01633 2.3e-232 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIMLPMKJ_01634 4.1e-50 czrA K Transcriptional regulator, ArsR family
PIMLPMKJ_01635 1.1e-34
PIMLPMKJ_01636 1.3e-84 L PFAM transposase IS200-family protein
PIMLPMKJ_01637 1.3e-227 clcA_2 P Chloride transporter, ClC family
PIMLPMKJ_01638 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
PIMLPMKJ_01639 9e-105 lssY 3.6.1.27 I Acid phosphatase homologues
PIMLPMKJ_01640 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PIMLPMKJ_01641 1.3e-35 ynzC S UPF0291 protein
PIMLPMKJ_01642 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
PIMLPMKJ_01643 1.6e-117 plsC 2.3.1.51 I Acyltransferase
PIMLPMKJ_01644 3e-139 yabB 2.1.1.223 L Methyltransferase small domain
PIMLPMKJ_01645 2.7e-48 yazA L GIY-YIG catalytic domain protein
PIMLPMKJ_01646 3.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIMLPMKJ_01647 3.5e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
PIMLPMKJ_01648 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PIMLPMKJ_01649 2.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PIMLPMKJ_01650 6.3e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PIMLPMKJ_01651 2.1e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PIMLPMKJ_01652 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
PIMLPMKJ_01653 3.1e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PIMLPMKJ_01654 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PIMLPMKJ_01655 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIMLPMKJ_01656 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
PIMLPMKJ_01657 1e-215 nusA K Participates in both transcription termination and antitermination
PIMLPMKJ_01658 1e-44 ylxR K Protein of unknown function (DUF448)
PIMLPMKJ_01659 6.4e-48 ylxQ J ribosomal protein
PIMLPMKJ_01660 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PIMLPMKJ_01661 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PIMLPMKJ_01662 1.2e-163 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PIMLPMKJ_01663 7.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PIMLPMKJ_01664 1.9e-62
PIMLPMKJ_01665 5.3e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PIMLPMKJ_01666 2.7e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PIMLPMKJ_01667 0.0 dnaK O Heat shock 70 kDa protein
PIMLPMKJ_01668 1.7e-194 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PIMLPMKJ_01669 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PIMLPMKJ_01670 8.2e-276 pipD E Dipeptidase
PIMLPMKJ_01671 6.4e-196 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PIMLPMKJ_01673 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PIMLPMKJ_01675 7.5e-58
PIMLPMKJ_01676 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
PIMLPMKJ_01677 8.2e-126 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PIMLPMKJ_01678 2.3e-51
PIMLPMKJ_01679 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PIMLPMKJ_01680 3.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PIMLPMKJ_01681 8.1e-162 yniA G Phosphotransferase enzyme family
PIMLPMKJ_01682 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PIMLPMKJ_01683 1.6e-129 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PIMLPMKJ_01684 2.8e-258 glnPH2 P ABC transporter permease
PIMLPMKJ_01685 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PIMLPMKJ_01686 1.9e-69 yqeY S YqeY-like protein
PIMLPMKJ_01687 9.3e-170 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PIMLPMKJ_01688 8.6e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PIMLPMKJ_01689 1.1e-261 argH 4.3.2.1 E argininosuccinate lyase
PIMLPMKJ_01690 7.7e-84 bioY S BioY family
PIMLPMKJ_01691 2.2e-163 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PIMLPMKJ_01692 9e-184 phoH T phosphate starvation-inducible protein PhoH
PIMLPMKJ_01693 4.7e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PIMLPMKJ_01694 4.2e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PIMLPMKJ_01695 6.6e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PIMLPMKJ_01696 4.9e-145 recO L Involved in DNA repair and RecF pathway recombination
PIMLPMKJ_01697 7.7e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PIMLPMKJ_01698 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PIMLPMKJ_01699 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PIMLPMKJ_01700 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PIMLPMKJ_01701 9.1e-220 patA 2.6.1.1 E Aminotransferase
PIMLPMKJ_01702 2.5e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
PIMLPMKJ_01703 8.8e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PIMLPMKJ_01704 5.3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PIMLPMKJ_01705 6.7e-30 S Protein of unknown function (DUF2929)
PIMLPMKJ_01706 0.0 dnaE 2.7.7.7 L DNA polymerase
PIMLPMKJ_01707 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PIMLPMKJ_01708 4.6e-168 cvfB S S1 domain
PIMLPMKJ_01709 1.2e-163 xerD D recombinase XerD
PIMLPMKJ_01710 8.1e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIMLPMKJ_01711 6.5e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PIMLPMKJ_01712 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PIMLPMKJ_01713 1.7e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PIMLPMKJ_01714 1.9e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PIMLPMKJ_01715 2e-186 ypbB 5.1.3.1 S Helix-turn-helix domain
PIMLPMKJ_01716 8.4e-260 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PIMLPMKJ_01717 8.5e-14 M Lysin motif
PIMLPMKJ_01718 6e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PIMLPMKJ_01719 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
PIMLPMKJ_01720 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PIMLPMKJ_01721 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIMLPMKJ_01722 1.1e-234 S Tetratricopeptide repeat protein
PIMLPMKJ_01723 7.9e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PIMLPMKJ_01724 0.0 yfmR S ABC transporter, ATP-binding protein
PIMLPMKJ_01725 1.2e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIMLPMKJ_01726 1.4e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIMLPMKJ_01727 7.7e-112 hlyIII S protein, hemolysin III
PIMLPMKJ_01728 2.7e-149 DegV S EDD domain protein, DegV family
PIMLPMKJ_01729 2.9e-165 ypmR E lipolytic protein G-D-S-L family
PIMLPMKJ_01730 9.1e-107 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PIMLPMKJ_01731 5.8e-35 yozE S Belongs to the UPF0346 family
PIMLPMKJ_01732 7.3e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PIMLPMKJ_01733 1.8e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIMLPMKJ_01734 2.8e-157 dprA LU DNA protecting protein DprA
PIMLPMKJ_01735 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIMLPMKJ_01736 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
PIMLPMKJ_01737 5.7e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIMLPMKJ_01738 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIMLPMKJ_01739 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIMLPMKJ_01740 9.6e-80 F NUDIX domain
PIMLPMKJ_01741 5.1e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
PIMLPMKJ_01742 8.6e-66 yqkB S Belongs to the HesB IscA family
PIMLPMKJ_01743 1.6e-49
PIMLPMKJ_01745 6.8e-84 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PIMLPMKJ_01746 1.4e-60 asp S Asp23 family, cell envelope-related function
PIMLPMKJ_01747 4.7e-25
PIMLPMKJ_01748 1.4e-93
PIMLPMKJ_01749 2.1e-285 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PIMLPMKJ_01750 6e-180 K Transcriptional regulator, LacI family
PIMLPMKJ_01751 6.9e-232 gntT EG Gluconate
PIMLPMKJ_01752 8.3e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PIMLPMKJ_01753 3.2e-95 K Acetyltransferase (GNAT) domain
PIMLPMKJ_01754 4.2e-47
PIMLPMKJ_01755 6.3e-23
PIMLPMKJ_01756 0.0 nylA 3.5.1.4 J Belongs to the amidase family
PIMLPMKJ_01757 1.1e-43
PIMLPMKJ_01758 2e-56 yhaI S Protein of unknown function (DUF805)
PIMLPMKJ_01759 1.7e-177 yfjM S Protein of unknown function DUF262
PIMLPMKJ_01760 3e-300 2.1.1.72 V type I restriction-modification system
PIMLPMKJ_01761 1.7e-61 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PIMLPMKJ_01762 3.8e-31 3.1.21.3 V Type I restriction modification DNA specificity domain
PIMLPMKJ_01763 6e-177 xerC L Belongs to the 'phage' integrase family
PIMLPMKJ_01764 1.9e-96 3.1.21.3 V Type I restriction modification DNA specificity domain
PIMLPMKJ_01765 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PIMLPMKJ_01766 1.9e-31 higA K addiction module antidote protein HigA
PIMLPMKJ_01768 7.1e-175 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PIMLPMKJ_01769 4.3e-103 T Ion transport 2 domain protein
PIMLPMKJ_01770 0.0 S Bacterial membrane protein YfhO
PIMLPMKJ_01771 8.9e-199 G Transporter, major facilitator family protein
PIMLPMKJ_01772 2.4e-109 yvrI K sigma factor activity
PIMLPMKJ_01773 9.4e-62 ydiI Q Thioesterase superfamily
PIMLPMKJ_01774 1e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PIMLPMKJ_01775 2.4e-259 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PIMLPMKJ_01776 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PIMLPMKJ_01777 9.6e-32 feoA P FeoA domain
PIMLPMKJ_01778 6.5e-145 sufC O FeS assembly ATPase SufC
PIMLPMKJ_01779 5.8e-236 sufD O FeS assembly protein SufD
PIMLPMKJ_01780 9.2e-231 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PIMLPMKJ_01781 1e-78 nifU C SUF system FeS assembly protein, NifU family
PIMLPMKJ_01782 1e-270 sufB O assembly protein SufB
PIMLPMKJ_01783 2.8e-57 yitW S Iron-sulfur cluster assembly protein
PIMLPMKJ_01784 1.4e-159 hipB K Helix-turn-helix
PIMLPMKJ_01785 9.8e-115 nreC K PFAM regulatory protein LuxR
PIMLPMKJ_01786 9.2e-39 S Cytochrome B5
PIMLPMKJ_01787 1.5e-152 yitU 3.1.3.104 S hydrolase
PIMLPMKJ_01788 1.8e-259 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PIMLPMKJ_01789 2.2e-146 f42a O Band 7 protein
PIMLPMKJ_01790 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
PIMLPMKJ_01791 1.2e-124 lytT K response regulator receiver
PIMLPMKJ_01792 4.1e-66 lrgA S LrgA family
PIMLPMKJ_01793 1.3e-123 lrgB M LrgB-like family
PIMLPMKJ_01794 4.2e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PIMLPMKJ_01795 8.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PIMLPMKJ_01796 4.8e-185 galR K Periplasmic binding protein-like domain
PIMLPMKJ_01797 0.0 rafA 3.2.1.22 G alpha-galactosidase
PIMLPMKJ_01798 2.5e-86 S Protein of unknown function (DUF1440)
PIMLPMKJ_01799 4.9e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PIMLPMKJ_01800 5.1e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PIMLPMKJ_01801 3.8e-163 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PIMLPMKJ_01802 1.3e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PIMLPMKJ_01803 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PIMLPMKJ_01804 3.4e-86 ypmB S Protein conserved in bacteria
PIMLPMKJ_01805 5.2e-122 dnaD L DnaD domain protein
PIMLPMKJ_01806 4.4e-161 EG EamA-like transporter family
PIMLPMKJ_01807 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PIMLPMKJ_01808 3.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIMLPMKJ_01809 3.9e-99 ypsA S Belongs to the UPF0398 family
PIMLPMKJ_01810 1.6e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PIMLPMKJ_01811 8e-82 F Belongs to the NrdI family
PIMLPMKJ_01812 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PIMLPMKJ_01813 2e-70 rnhA 3.1.26.4 L Ribonuclease HI
PIMLPMKJ_01814 1.5e-65 esbA S Family of unknown function (DUF5322)
PIMLPMKJ_01815 2.7e-71 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PIMLPMKJ_01816 4.6e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PIMLPMKJ_01817 4.3e-208 carA 6.3.5.5 F Belongs to the CarA family
PIMLPMKJ_01818 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PIMLPMKJ_01819 0.0 FbpA K Fibronectin-binding protein
PIMLPMKJ_01820 1.1e-161 degV S EDD domain protein, DegV family
PIMLPMKJ_01821 1e-92
PIMLPMKJ_01822 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PIMLPMKJ_01823 1.3e-156 gspA M family 8
PIMLPMKJ_01824 4.9e-159 S Alpha beta hydrolase
PIMLPMKJ_01825 2.4e-95 K Acetyltransferase (GNAT) domain
PIMLPMKJ_01826 6.9e-240 XK27_08635 S UPF0210 protein
PIMLPMKJ_01827 6.1e-39 gcvR T Belongs to the UPF0237 family
PIMLPMKJ_01828 5.7e-166 1.1.1.346 C Aldo keto reductase
PIMLPMKJ_01829 1.3e-157 K LysR substrate binding domain protein
PIMLPMKJ_01830 8.5e-84 C Flavodoxin
PIMLPMKJ_01831 7.2e-79 yphH S Cupin domain
PIMLPMKJ_01832 7.6e-74 yeaL S UPF0756 membrane protein
PIMLPMKJ_01833 9.9e-242 EGP Major facilitator Superfamily
PIMLPMKJ_01834 1.9e-74 copY K Copper transport repressor CopY TcrY
PIMLPMKJ_01835 8e-244 yhdP S Transporter associated domain
PIMLPMKJ_01836 0.0 ubiB S ABC1 family
PIMLPMKJ_01837 1.9e-136 S DUF218 domain
PIMLPMKJ_01838 1.2e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIMLPMKJ_01839 1e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIMLPMKJ_01840 6.5e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIMLPMKJ_01841 0.0 uvrA3 L excinuclease ABC, A subunit
PIMLPMKJ_01842 2.3e-122 S SNARE associated Golgi protein
PIMLPMKJ_01843 3.5e-230 N Uncharacterized conserved protein (DUF2075)
PIMLPMKJ_01844 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PIMLPMKJ_01846 3.9e-254 yifK E Amino acid permease
PIMLPMKJ_01847 4.6e-157 endA V DNA/RNA non-specific endonuclease
PIMLPMKJ_01848 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIMLPMKJ_01849 1.6e-39 ybaN S Protein of unknown function (DUF454)
PIMLPMKJ_01850 6.5e-70 S Protein of unknown function (DUF3290)
PIMLPMKJ_01851 1.4e-113 yviA S Protein of unknown function (DUF421)
PIMLPMKJ_01852 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
PIMLPMKJ_01853 5.4e-19
PIMLPMKJ_01854 6.2e-90 ntd 2.4.2.6 F Nucleoside
PIMLPMKJ_01855 2.1e-146 3.1.3.102, 3.1.3.104 S hydrolase
PIMLPMKJ_01856 2e-45 yrvD S Pfam:DUF1049
PIMLPMKJ_01858 5.2e-164 I alpha/beta hydrolase fold
PIMLPMKJ_01859 8.2e-114 frnE Q DSBA-like thioredoxin domain
PIMLPMKJ_01860 2.3e-54
PIMLPMKJ_01861 4e-92 L Transposase
PIMLPMKJ_01862 4.8e-59 L Transposase
PIMLPMKJ_01871 3.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PIMLPMKJ_01872 2e-135 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PIMLPMKJ_01873 3.2e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PIMLPMKJ_01874 1.5e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PIMLPMKJ_01875 1.5e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PIMLPMKJ_01876 1.2e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PIMLPMKJ_01877 4.9e-224 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIMLPMKJ_01878 7.3e-127 IQ reductase
PIMLPMKJ_01879 1.9e-159 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PIMLPMKJ_01880 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIMLPMKJ_01881 2.9e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PIMLPMKJ_01882 5.5e-77 marR K Transcriptional regulator, MarR family
PIMLPMKJ_01883 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PIMLPMKJ_01885 5.2e-198 xerS L Belongs to the 'phage' integrase family
PIMLPMKJ_01886 9.8e-250 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
PIMLPMKJ_01887 2.7e-157 rssA S Phospholipase, patatin family
PIMLPMKJ_01888 2.5e-118 L Integrase
PIMLPMKJ_01889 2.7e-147 EG EamA-like transporter family
PIMLPMKJ_01890 5.3e-127 narI 1.7.5.1 C Nitrate reductase
PIMLPMKJ_01891 9e-96 narJ C nitrate reductase molybdenum cofactor assembly chaperone
PIMLPMKJ_01892 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
PIMLPMKJ_01893 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PIMLPMKJ_01894 1.1e-176 moeB 2.7.7.73, 2.7.7.80 H ThiF family
PIMLPMKJ_01895 5e-79 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PIMLPMKJ_01896 5e-221 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
PIMLPMKJ_01897 4.8e-74 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PIMLPMKJ_01898 4.1e-93 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PIMLPMKJ_01899 2e-43
PIMLPMKJ_01900 2.1e-183 comP 2.7.13.3 F Sensor histidine kinase
PIMLPMKJ_01901 6.3e-114 nreC K PFAM regulatory protein LuxR
PIMLPMKJ_01902 1.6e-18
PIMLPMKJ_01903 2.4e-170
PIMLPMKJ_01904 3.1e-143 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
PIMLPMKJ_01905 1.9e-217 narK P Transporter, major facilitator family protein
PIMLPMKJ_01906 2.1e-30 moaD 2.8.1.12 H ThiS family
PIMLPMKJ_01907 2e-62 moaE 2.8.1.12 H MoaE protein
PIMLPMKJ_01908 5.8e-74 S Flavodoxin
PIMLPMKJ_01909 6.2e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIMLPMKJ_01910 1.4e-128 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
PIMLPMKJ_01911 5e-174 fecB P Periplasmic binding protein
PIMLPMKJ_01912 9.2e-170
PIMLPMKJ_01913 2.5e-74
PIMLPMKJ_01914 5.6e-118 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
PIMLPMKJ_01915 0.0 S SEC-C Motif Domain Protein
PIMLPMKJ_01916 1.2e-51
PIMLPMKJ_01917 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PIMLPMKJ_01918 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PIMLPMKJ_01919 4e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PIMLPMKJ_01920 5.4e-49 L PFAM transposase IS200-family protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)