ORF_ID e_value Gene_name EC_number CAZy COGs Description
JNHNGPDM_00001 1.4e-72
JNHNGPDM_00002 3.5e-24
JNHNGPDM_00003 4.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JNHNGPDM_00004 1.3e-260 S Putative peptidoglycan binding domain
JNHNGPDM_00007 7.2e-79 2.7.13.3 T GHKL domain
JNHNGPDM_00008 2.8e-207 araR K Transcriptional regulator
JNHNGPDM_00009 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
JNHNGPDM_00010 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
JNHNGPDM_00011 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JNHNGPDM_00012 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
JNHNGPDM_00013 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
JNHNGPDM_00014 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
JNHNGPDM_00015 7.2e-96 L Helix-turn-helix domain
JNHNGPDM_00016 2.5e-139 L hmm pf00665
JNHNGPDM_00017 3.3e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
JNHNGPDM_00019 0.0 lacS G Transporter
JNHNGPDM_00020 6.1e-39
JNHNGPDM_00021 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JNHNGPDM_00022 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JNHNGPDM_00023 3.1e-193 yeaN P Transporter, major facilitator family protein
JNHNGPDM_00024 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
JNHNGPDM_00025 9.9e-85 nrdI F Belongs to the NrdI family
JNHNGPDM_00026 6.2e-241 yhdP S Transporter associated domain
JNHNGPDM_00027 1.7e-154 ypdB V (ABC) transporter
JNHNGPDM_00028 4.8e-88 GM epimerase
JNHNGPDM_00029 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
JNHNGPDM_00030 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
JNHNGPDM_00031 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
JNHNGPDM_00032 2.8e-170 S AI-2E family transporter
JNHNGPDM_00033 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
JNHNGPDM_00034 2.3e-162
JNHNGPDM_00035 1.4e-124 yciB M ErfK YbiS YcfS YnhG
JNHNGPDM_00037 2.5e-101
JNHNGPDM_00038 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JNHNGPDM_00039 7.5e-123 S Alpha beta hydrolase
JNHNGPDM_00040 1.7e-207 gldA 1.1.1.6 C dehydrogenase
JNHNGPDM_00041 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JNHNGPDM_00042 1.3e-41
JNHNGPDM_00043 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
JNHNGPDM_00044 1.4e-284 S C4-dicarboxylate anaerobic carrier
JNHNGPDM_00045 1.8e-251 nhaC C Na H antiporter NhaC
JNHNGPDM_00046 1.6e-241 pbuX F xanthine permease
JNHNGPDM_00047 1.4e-283 pipD E Dipeptidase
JNHNGPDM_00048 7e-289 L Transposase
JNHNGPDM_00049 8.2e-168 corA P CorA-like Mg2+ transporter protein
JNHNGPDM_00050 2.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JNHNGPDM_00051 2.3e-131 terC P membrane
JNHNGPDM_00052 2.1e-54 trxA O Belongs to the thioredoxin family
JNHNGPDM_00053 1.6e-236 mepA V MATE efflux family protein
JNHNGPDM_00054 6.6e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JNHNGPDM_00055 1.3e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
JNHNGPDM_00056 3e-238 S polysaccharide biosynthetic process
JNHNGPDM_00057 7.8e-233 S Psort location CytoplasmicMembrane, score 9.99
JNHNGPDM_00058 7.5e-183 M Glycosyl transferase, family 2
JNHNGPDM_00059 5.4e-181 GT2 M Glycosyltransferase like family 2
JNHNGPDM_00060 1.8e-184 M family 8
JNHNGPDM_00061 2e-194 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JNHNGPDM_00062 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JNHNGPDM_00063 3.7e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JNHNGPDM_00064 5.7e-115 rfbP M Bacterial sugar transferase
JNHNGPDM_00065 8.5e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
JNHNGPDM_00066 3.8e-146 epsB M biosynthesis protein
JNHNGPDM_00067 2.4e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JNHNGPDM_00068 3e-41 K Transcriptional regulator, HxlR family
JNHNGPDM_00069 9.3e-62 K DNA-templated transcription, initiation
JNHNGPDM_00070 2.8e-35
JNHNGPDM_00071 5.9e-114 L PFAM Integrase catalytic region
JNHNGPDM_00072 1.5e-253 EGP Major facilitator Superfamily
JNHNGPDM_00073 4.3e-85 perR P Belongs to the Fur family
JNHNGPDM_00074 4.8e-233 cycA E Amino acid permease
JNHNGPDM_00075 2.8e-102 V VanZ like family
JNHNGPDM_00076 1e-23
JNHNGPDM_00077 7.7e-86 S Short repeat of unknown function (DUF308)
JNHNGPDM_00078 2.9e-78 S Psort location Cytoplasmic, score
JNHNGPDM_00079 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
JNHNGPDM_00080 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
JNHNGPDM_00081 8.1e-154 yeaE S Aldo keto
JNHNGPDM_00082 4.5e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
JNHNGPDM_00083 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
JNHNGPDM_00084 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
JNHNGPDM_00085 2.3e-93 lytE M LysM domain protein
JNHNGPDM_00086 0.0 oppD EP Psort location Cytoplasmic, score
JNHNGPDM_00087 2.6e-80 lytE M LysM domain protein
JNHNGPDM_00088 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
JNHNGPDM_00089 1.7e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JNHNGPDM_00090 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JNHNGPDM_00091 1.5e-237 lmrB EGP Major facilitator Superfamily
JNHNGPDM_00092 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
JNHNGPDM_00093 3.5e-181 3.5.1.104 M hydrolase, family 25
JNHNGPDM_00094 1.3e-56 S Bacteriophage holin of superfamily 6 (Holin_LLH)
JNHNGPDM_00095 3.2e-33
JNHNGPDM_00097 0.0 cotH M CotH kinase protein
JNHNGPDM_00099 0.0 M Prophage endopeptidase tail
JNHNGPDM_00100 6.1e-148 S phage tail
JNHNGPDM_00101 1.3e-255 sca1 D Phage tail tape measure protein
JNHNGPDM_00102 2.7e-61
JNHNGPDM_00103 4.2e-53 S Phage tail assembly chaperone protein, TAC
JNHNGPDM_00104 9.1e-104 S Phage tail tube protein
JNHNGPDM_00105 3.4e-22 S Protein of unknown function (DUF3168)
JNHNGPDM_00106 3.6e-67 S Bacteriophage HK97-gp10, putative tail-component
JNHNGPDM_00107 1.3e-43
JNHNGPDM_00108 2.1e-64 S Phage gp6-like head-tail connector protein
JNHNGPDM_00109 2.9e-154
JNHNGPDM_00110 8.9e-102 S Domain of unknown function (DUF4355)
JNHNGPDM_00111 6.3e-33 S YjcQ protein
JNHNGPDM_00113 5.4e-238 S Phage Mu protein F like protein
JNHNGPDM_00114 9.5e-272 S Phage portal protein
JNHNGPDM_00115 9.7e-222 S Phage terminase, large subunit
JNHNGPDM_00116 4.4e-09 S Phage terminase, large subunit
JNHNGPDM_00117 1.8e-61 L Terminase small subunit
JNHNGPDM_00118 1.9e-72 arpU S Phage transcriptional regulator, ArpU family
JNHNGPDM_00123 1.4e-10
JNHNGPDM_00125 8.8e-59 S VRR_NUC
JNHNGPDM_00127 2.2e-224 S Virulence-associated protein E
JNHNGPDM_00128 4.2e-144 S Bifunctional DNA primase/polymerase, N-terminal
JNHNGPDM_00129 1.7e-93
JNHNGPDM_00130 9.3e-141 L AAA domain
JNHNGPDM_00131 3.4e-258 res L Helicase C-terminal domain protein
JNHNGPDM_00132 2.5e-08
JNHNGPDM_00133 2.8e-82 S Siphovirus Gp157
JNHNGPDM_00135 8.4e-31
JNHNGPDM_00138 3.5e-36
JNHNGPDM_00139 8.8e-118 K ORF6N domain
JNHNGPDM_00140 1.8e-30 K Helix-turn-helix XRE-family like proteins
JNHNGPDM_00141 2.7e-58 K Transcriptional regulator, Cro CI family
JNHNGPDM_00143 7.1e-72
JNHNGPDM_00144 9.3e-121 S Domain of unknown function (DUF5067)
JNHNGPDM_00145 1.2e-141 L Belongs to the 'phage' integrase family
JNHNGPDM_00153 3.2e-83 F Belongs to the NrdI family
JNHNGPDM_00154 1.2e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JNHNGPDM_00155 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
JNHNGPDM_00156 1.5e-65 esbA S Family of unknown function (DUF5322)
JNHNGPDM_00157 1.3e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JNHNGPDM_00158 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JNHNGPDM_00159 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
JNHNGPDM_00160 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JNHNGPDM_00161 0.0 FbpA K Fibronectin-binding protein
JNHNGPDM_00162 1.9e-161 degV S EDD domain protein, DegV family
JNHNGPDM_00163 1.1e-92
JNHNGPDM_00164 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JNHNGPDM_00165 1.1e-158 gspA M family 8
JNHNGPDM_00166 1.2e-160 S Alpha beta hydrolase
JNHNGPDM_00167 7.6e-94 K Acetyltransferase (GNAT) domain
JNHNGPDM_00168 1.1e-240 XK27_08635 S UPF0210 protein
JNHNGPDM_00169 2.1e-39 gcvR T Belongs to the UPF0237 family
JNHNGPDM_00170 5.9e-163 1.1.1.346 C Aldo keto reductase
JNHNGPDM_00171 1.1e-60 K LysR substrate binding domain protein
JNHNGPDM_00172 1.5e-80 C Flavodoxin
JNHNGPDM_00173 4.1e-37 S Uncharacterised protein family (UPF0236)
JNHNGPDM_00174 8.6e-59 lsa S ABC transporter
JNHNGPDM_00175 7.5e-168 lsa S ABC transporter
JNHNGPDM_00176 3.5e-134 I alpha/beta hydrolase fold
JNHNGPDM_00177 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
JNHNGPDM_00178 1.8e-220 G Belongs to the glycosyl hydrolase family 6
JNHNGPDM_00179 1.3e-96 S NADPH-dependent FMN reductase
JNHNGPDM_00180 7.4e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JNHNGPDM_00181 2.6e-68 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JNHNGPDM_00182 5.7e-82 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JNHNGPDM_00183 3.1e-229 mntH P H( )-stimulated, divalent metal cation uptake system
JNHNGPDM_00184 1.2e-81 Q Methyltransferase
JNHNGPDM_00185 1.4e-116 ktrA P domain protein
JNHNGPDM_00186 1.7e-238 ktrB P Potassium uptake protein
JNHNGPDM_00187 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
JNHNGPDM_00188 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JNHNGPDM_00189 4.8e-218 G Glycosyl hydrolases family 8
JNHNGPDM_00190 2.2e-243 ydaM M Glycosyl transferase
JNHNGPDM_00191 8e-141
JNHNGPDM_00192 4.1e-37 S Uncharacterised protein family (UPF0236)
JNHNGPDM_00193 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
JNHNGPDM_00194 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JNHNGPDM_00195 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JNHNGPDM_00196 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JNHNGPDM_00197 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JNHNGPDM_00198 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JNHNGPDM_00199 2.8e-31 yajC U Preprotein translocase
JNHNGPDM_00200 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
JNHNGPDM_00201 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JNHNGPDM_00202 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JNHNGPDM_00203 4.1e-43 yrzL S Belongs to the UPF0297 family
JNHNGPDM_00204 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JNHNGPDM_00205 6.1e-48 yrzB S Belongs to the UPF0473 family
JNHNGPDM_00206 1e-85 cvpA S Colicin V production protein
JNHNGPDM_00207 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JNHNGPDM_00208 6.1e-54 trxA O Belongs to the thioredoxin family
JNHNGPDM_00209 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JNHNGPDM_00210 6.1e-198 XK27_09615 S reductase
JNHNGPDM_00211 1.2e-100 nqr 1.5.1.36 S reductase
JNHNGPDM_00213 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JNHNGPDM_00214 2.4e-181 K Transcriptional regulator, LacI family
JNHNGPDM_00215 3e-259 G Major Facilitator
JNHNGPDM_00216 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JNHNGPDM_00217 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JNHNGPDM_00218 4.5e-49 G Major Facilitator
JNHNGPDM_00219 3.8e-188 G Major Facilitator
JNHNGPDM_00220 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
JNHNGPDM_00221 2.4e-277 M domain protein
JNHNGPDM_00222 7.9e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
JNHNGPDM_00223 4.8e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
JNHNGPDM_00224 2.2e-72
JNHNGPDM_00225 6.2e-76 K Transcriptional regulator, TetR family
JNHNGPDM_00226 2.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JNHNGPDM_00227 1.7e-183 S Phosphotransferase system, EIIC
JNHNGPDM_00228 1.6e-52 azlD S branched-chain amino acid
JNHNGPDM_00229 3.7e-136 azlC E AzlC protein
JNHNGPDM_00230 4.2e-198 hpk31 2.7.13.3 T Histidine kinase
JNHNGPDM_00231 1.2e-123 K response regulator
JNHNGPDM_00232 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JNHNGPDM_00233 2.8e-171 deoR K sugar-binding domain protein
JNHNGPDM_00234 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JNHNGPDM_00235 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
JNHNGPDM_00236 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JNHNGPDM_00237 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JNHNGPDM_00238 2.6e-135 XK27_01040 S Protein of unknown function (DUF1129)
JNHNGPDM_00239 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JNHNGPDM_00240 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
JNHNGPDM_00241 1.7e-154 spo0J K Belongs to the ParB family
JNHNGPDM_00242 3.9e-139 soj D Sporulation initiation inhibitor
JNHNGPDM_00243 4.3e-151 noc K Belongs to the ParB family
JNHNGPDM_00244 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
JNHNGPDM_00245 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
JNHNGPDM_00246 5.6e-169 rihC 3.2.2.1 F Nucleoside
JNHNGPDM_00247 2.3e-218 nupG F Nucleoside transporter
JNHNGPDM_00248 2.5e-221 cycA E Amino acid permease
JNHNGPDM_00249 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JNHNGPDM_00250 1.2e-264 glnP P ABC transporter
JNHNGPDM_00251 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JNHNGPDM_00252 4.5e-160 L hmm pf00665
JNHNGPDM_00253 4.4e-100 L Helix-turn-helix domain
JNHNGPDM_00254 9.8e-169 L Transposase and inactivated derivatives IS30 family
JNHNGPDM_00255 6.5e-165 czcD P cation diffusion facilitator family transporter
JNHNGPDM_00256 2.4e-124 sirR K iron dependent repressor
JNHNGPDM_00257 3.5e-31 cspC K Cold shock protein
JNHNGPDM_00258 3.6e-129 thrE S Putative threonine/serine exporter
JNHNGPDM_00259 6.7e-81 S Threonine/Serine exporter, ThrE
JNHNGPDM_00260 2.7e-120 lssY 3.6.1.27 I phosphatase
JNHNGPDM_00261 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
JNHNGPDM_00262 1.5e-275 lysP E amino acid
JNHNGPDM_00263 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
JNHNGPDM_00269 4.8e-131 S Hydrolases of the alpha beta superfamily
JNHNGPDM_00270 1.3e-16 S Hydrolases of the alpha beta superfamily
JNHNGPDM_00271 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
JNHNGPDM_00272 3.4e-77 ctsR K Belongs to the CtsR family
JNHNGPDM_00273 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
JNHNGPDM_00274 1e-110 K Bacterial regulatory proteins, tetR family
JNHNGPDM_00275 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JNHNGPDM_00276 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JNHNGPDM_00277 6.5e-202 ykiI
JNHNGPDM_00278 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
JNHNGPDM_00279 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JNHNGPDM_00280 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JNHNGPDM_00281 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JNHNGPDM_00282 9.8e-169 L Transposase and inactivated derivatives IS30 family
JNHNGPDM_00283 8.2e-48
JNHNGPDM_00284 7.8e-272 S ABC transporter, ATP-binding protein
JNHNGPDM_00285 2.3e-142 S Putative ABC-transporter type IV
JNHNGPDM_00286 2e-106 NU mannosyl-glycoprotein
JNHNGPDM_00287 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
JNHNGPDM_00288 3.3e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
JNHNGPDM_00289 7.6e-205 nrnB S DHHA1 domain
JNHNGPDM_00291 6.9e-49
JNHNGPDM_00292 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JNHNGPDM_00293 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JNHNGPDM_00294 2e-15 S Domain of unknown function (DUF4767)
JNHNGPDM_00295 9.5e-55
JNHNGPDM_00296 2.9e-117 yrkL S Flavodoxin-like fold
JNHNGPDM_00298 1.6e-64 yeaO S Protein of unknown function, DUF488
JNHNGPDM_00299 6.3e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JNHNGPDM_00300 3e-204 3.1.3.1 S associated with various cellular activities
JNHNGPDM_00301 9.3e-242 S Putative metallopeptidase domain
JNHNGPDM_00302 5.1e-47
JNHNGPDM_00303 0.0 pepO 3.4.24.71 O Peptidase family M13
JNHNGPDM_00304 3.2e-110 K Helix-turn-helix domain
JNHNGPDM_00305 5.6e-86 ymdB S Macro domain protein
JNHNGPDM_00306 2.1e-197 EGP Major facilitator Superfamily
JNHNGPDM_00307 4.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNHNGPDM_00308 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JNHNGPDM_00309 5.3e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
JNHNGPDM_00310 0.0 ysaB V FtsX-like permease family
JNHNGPDM_00311 2.1e-132 macB2 V ABC transporter, ATP-binding protein
JNHNGPDM_00312 3.8e-179 T PhoQ Sensor
JNHNGPDM_00313 1.7e-131 K response regulator
JNHNGPDM_00314 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
JNHNGPDM_00315 8.9e-136 pnuC H nicotinamide mononucleotide transporter
JNHNGPDM_00316 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JNHNGPDM_00317 2.3e-204
JNHNGPDM_00318 2.6e-52
JNHNGPDM_00319 9.1e-36
JNHNGPDM_00320 2.4e-92 yxkA S Phosphatidylethanolamine-binding protein
JNHNGPDM_00321 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
JNHNGPDM_00322 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
JNHNGPDM_00323 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JNHNGPDM_00324 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JNHNGPDM_00325 2e-180 galR K Transcriptional regulator
JNHNGPDM_00326 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
JNHNGPDM_00327 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JNHNGPDM_00328 1.5e-80 K AsnC family
JNHNGPDM_00329 1.5e-80 uspA T universal stress protein
JNHNGPDM_00330 1.1e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
JNHNGPDM_00331 9.8e-169 L Transposase and inactivated derivatives IS30 family
JNHNGPDM_00332 8.5e-73 M PFAM NLP P60 protein
JNHNGPDM_00333 2.2e-182 ABC-SBP S ABC transporter
JNHNGPDM_00334 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
JNHNGPDM_00335 1.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
JNHNGPDM_00336 1.2e-92 P Cadmium resistance transporter
JNHNGPDM_00337 6.8e-56 K Transcriptional regulator, ArsR family
JNHNGPDM_00338 4.2e-55 M Leucine-rich repeat (LRR) protein
JNHNGPDM_00339 9.8e-169 L Transposase and inactivated derivatives IS30 family
JNHNGPDM_00340 1.6e-115 S membrane
JNHNGPDM_00341 8.4e-109 S VIT family
JNHNGPDM_00342 5.5e-83 usp1 T Belongs to the universal stress protein A family
JNHNGPDM_00343 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JNHNGPDM_00344 1.4e-150 glnH ET ABC transporter
JNHNGPDM_00345 4.2e-110 gluC P ABC transporter permease
JNHNGPDM_00346 1.4e-108 glnP P ABC transporter permease
JNHNGPDM_00347 1.5e-217 S CAAX protease self-immunity
JNHNGPDM_00348 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JNHNGPDM_00349 2.5e-53
JNHNGPDM_00350 4.9e-73 merR K MerR HTH family regulatory protein
JNHNGPDM_00351 1e-268 lmrB EGP Major facilitator Superfamily
JNHNGPDM_00352 2e-116 S Domain of unknown function (DUF4811)
JNHNGPDM_00353 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JNHNGPDM_00355 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JNHNGPDM_00356 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
JNHNGPDM_00357 3.4e-188 I Alpha beta
JNHNGPDM_00358 8.5e-282 emrY EGP Major facilitator Superfamily
JNHNGPDM_00359 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
JNHNGPDM_00360 2e-250 yjjP S Putative threonine/serine exporter
JNHNGPDM_00361 1e-159 mleR K LysR family
JNHNGPDM_00362 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JNHNGPDM_00364 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
JNHNGPDM_00365 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
JNHNGPDM_00366 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JNHNGPDM_00367 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JNHNGPDM_00368 1.2e-10 S Protein of unknown function (DUF4044)
JNHNGPDM_00369 7.3e-56
JNHNGPDM_00370 3.1e-77 mraZ K Belongs to the MraZ family
JNHNGPDM_00371 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JNHNGPDM_00372 2.6e-56 ftsL D Cell division protein FtsL
JNHNGPDM_00373 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JNHNGPDM_00374 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JNHNGPDM_00375 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JNHNGPDM_00376 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JNHNGPDM_00377 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JNHNGPDM_00378 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JNHNGPDM_00379 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JNHNGPDM_00380 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JNHNGPDM_00381 3.2e-40 yggT S YGGT family
JNHNGPDM_00382 5.1e-142 ylmH S S4 domain protein
JNHNGPDM_00383 1.9e-42 divIVA D DivIVA domain protein
JNHNGPDM_00384 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JNHNGPDM_00385 4.2e-32 cspA K Cold shock protein
JNHNGPDM_00386 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
JNHNGPDM_00388 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JNHNGPDM_00389 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
JNHNGPDM_00390 3.7e-57 XK27_04120 S Putative amino acid metabolism
JNHNGPDM_00391 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JNHNGPDM_00392 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
JNHNGPDM_00393 2.6e-118 S Repeat protein
JNHNGPDM_00394 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JNHNGPDM_00395 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JNHNGPDM_00397 4.4e-100 L Helix-turn-helix domain
JNHNGPDM_00398 4.5e-160 L hmm pf00665
JNHNGPDM_00399 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JNHNGPDM_00400 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JNHNGPDM_00401 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JNHNGPDM_00402 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JNHNGPDM_00403 4.5e-49 ylxQ J ribosomal protein
JNHNGPDM_00404 1e-44 ylxR K Protein of unknown function (DUF448)
JNHNGPDM_00405 6.8e-215 nusA K Participates in both transcription termination and antitermination
JNHNGPDM_00406 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
JNHNGPDM_00407 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JNHNGPDM_00408 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JNHNGPDM_00409 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JNHNGPDM_00410 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
JNHNGPDM_00411 3.5e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JNHNGPDM_00412 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JNHNGPDM_00413 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JNHNGPDM_00414 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JNHNGPDM_00415 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
JNHNGPDM_00416 9.8e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNHNGPDM_00417 5.4e-49 yazA L GIY-YIG catalytic domain protein
JNHNGPDM_00418 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
JNHNGPDM_00419 1e-116 plsC 2.3.1.51 I Acyltransferase
JNHNGPDM_00420 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
JNHNGPDM_00421 1.3e-35 ynzC S UPF0291 protein
JNHNGPDM_00422 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JNHNGPDM_00423 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
JNHNGPDM_00424 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JNHNGPDM_00426 2.1e-87
JNHNGPDM_00427 7.8e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JNHNGPDM_00428 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JNHNGPDM_00429 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JNHNGPDM_00430 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JNHNGPDM_00431 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JNHNGPDM_00432 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JNHNGPDM_00433 1.3e-08
JNHNGPDM_00434 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JNHNGPDM_00435 0.0 uup S ABC transporter, ATP-binding protein
JNHNGPDM_00436 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JNHNGPDM_00437 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
JNHNGPDM_00438 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
JNHNGPDM_00439 1.2e-135 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JNHNGPDM_00440 7.3e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JNHNGPDM_00441 1.8e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNHNGPDM_00442 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JNHNGPDM_00443 1.2e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
JNHNGPDM_00444 7e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
JNHNGPDM_00445 5.9e-114 L PFAM Integrase catalytic region
JNHNGPDM_00446 1.5e-17 NU Mycoplasma protein of unknown function, DUF285
JNHNGPDM_00448 1.2e-157 metQ_4 P Belongs to the nlpA lipoprotein family
JNHNGPDM_00449 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JNHNGPDM_00450 1.2e-64 O Zinc-dependent metalloprotease
JNHNGPDM_00451 4.7e-111 S Membrane
JNHNGPDM_00452 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JNHNGPDM_00453 2.2e-36 S Domain of unknown function DUF1829
JNHNGPDM_00454 7.5e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JNHNGPDM_00455 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JNHNGPDM_00456 3.9e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JNHNGPDM_00457 5.6e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JNHNGPDM_00458 3.5e-35
JNHNGPDM_00459 2.5e-212 bacI V MacB-like periplasmic core domain
JNHNGPDM_00460 7.7e-126 V ABC transporter
JNHNGPDM_00461 9.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JNHNGPDM_00462 1.4e-245 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
JNHNGPDM_00463 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNHNGPDM_00464 2.7e-148 E Glyoxalase-like domain
JNHNGPDM_00465 7.5e-155 glcU U sugar transport
JNHNGPDM_00466 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
JNHNGPDM_00467 2.2e-96 S reductase
JNHNGPDM_00468 1.4e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JNHNGPDM_00469 1.7e-179 ABC-SBP S ABC transporter
JNHNGPDM_00470 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
JNHNGPDM_00471 2.5e-215 htrA 3.4.21.107 O serine protease
JNHNGPDM_00472 4.5e-154 vicX 3.1.26.11 S domain protein
JNHNGPDM_00473 2.7e-149 yycI S YycH protein
JNHNGPDM_00474 2.1e-246 yycH S YycH protein
JNHNGPDM_00475 0.0 vicK 2.7.13.3 T Histidine kinase
JNHNGPDM_00476 6.8e-130 K response regulator
JNHNGPDM_00478 5.2e-309 lmrA 3.6.3.44 V ABC transporter
JNHNGPDM_00479 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
JNHNGPDM_00481 2e-87 S Glycosyltransferase like family
JNHNGPDM_00482 1.4e-83 M Domain of unknown function (DUF4422)
JNHNGPDM_00483 4.1e-41 M biosynthesis protein
JNHNGPDM_00484 1.4e-95 cps3F
JNHNGPDM_00485 5.9e-97 M Glycosyltransferase like family 2
JNHNGPDM_00486 2.1e-116 S Glycosyltransferase like family 2
JNHNGPDM_00487 2.2e-75 rgpB GT2 M Glycosyl transferase family 2
JNHNGPDM_00488 4.8e-215 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
JNHNGPDM_00489 2.8e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
JNHNGPDM_00490 0.0 ganB 3.2.1.89 G arabinogalactan
JNHNGPDM_00491 2.1e-25
JNHNGPDM_00492 0.0 G Peptidase_C39 like family
JNHNGPDM_00493 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
JNHNGPDM_00494 1.8e-267 frdC 1.3.5.4 C FAD binding domain
JNHNGPDM_00495 1.4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JNHNGPDM_00496 7.4e-305 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
JNHNGPDM_00497 1.9e-161 mleR K LysR family
JNHNGPDM_00498 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JNHNGPDM_00499 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
JNHNGPDM_00500 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
JNHNGPDM_00501 7.2e-169 L transposase, IS605 OrfB family
JNHNGPDM_00502 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
JNHNGPDM_00503 1.5e-25
JNHNGPDM_00504 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JNHNGPDM_00505 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JNHNGPDM_00507 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JNHNGPDM_00508 4.5e-62 psiE S Phosphate-starvation-inducible E
JNHNGPDM_00509 2.1e-102 ydeN S Serine hydrolase
JNHNGPDM_00511 3.4e-155 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JNHNGPDM_00512 6.1e-255 nhaC C Na H antiporter NhaC
JNHNGPDM_00513 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
JNHNGPDM_00514 4.8e-114 ywnB S NAD(P)H-binding
JNHNGPDM_00515 9.2e-36
JNHNGPDM_00516 9.3e-130 IQ Dehydrogenase reductase
JNHNGPDM_00517 1.5e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
JNHNGPDM_00519 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JNHNGPDM_00520 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JNHNGPDM_00521 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JNHNGPDM_00522 3.4e-35 nrdH O Glutaredoxin
JNHNGPDM_00523 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JNHNGPDM_00524 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JNHNGPDM_00525 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JNHNGPDM_00526 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JNHNGPDM_00527 9.7e-39 S Protein of unknown function (DUF2508)
JNHNGPDM_00528 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JNHNGPDM_00529 7.6e-52 yaaQ S Cyclic-di-AMP receptor
JNHNGPDM_00530 2.8e-185 holB 2.7.7.7 L DNA polymerase III
JNHNGPDM_00531 5.9e-58 yabA L Involved in initiation control of chromosome replication
JNHNGPDM_00532 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JNHNGPDM_00533 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
JNHNGPDM_00534 7.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JNHNGPDM_00535 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JNHNGPDM_00536 1.8e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JNHNGPDM_00537 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JNHNGPDM_00538 3.8e-70 yqeY S YqeY-like protein
JNHNGPDM_00539 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JNHNGPDM_00540 5.9e-264 glnPH2 P ABC transporter permease
JNHNGPDM_00541 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JNHNGPDM_00542 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JNHNGPDM_00543 1e-164 yniA G Phosphotransferase enzyme family
JNHNGPDM_00544 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JNHNGPDM_00545 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JNHNGPDM_00546 1.2e-52
JNHNGPDM_00547 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JNHNGPDM_00548 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
JNHNGPDM_00549 2.8e-57
JNHNGPDM_00551 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JNHNGPDM_00553 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
JNHNGPDM_00554 4.1e-275 pipD E Dipeptidase
JNHNGPDM_00555 1.5e-89 K IrrE N-terminal-like domain
JNHNGPDM_00556 2e-30
JNHNGPDM_00557 3.2e-198 3.5.1.104 M hydrolase, family 25
JNHNGPDM_00558 9.8e-63 S Bacteriophage holin of superfamily 6 (Holin_LLH)
JNHNGPDM_00559 5.3e-15
JNHNGPDM_00564 0.0 cotH M CotH kinase protein
JNHNGPDM_00566 9.5e-259 3.4.24.40 M Peptidase family M23
JNHNGPDM_00567 4.1e-158 S Phage tail protein
JNHNGPDM_00568 0.0 M Phage tail tape measure protein TP901
JNHNGPDM_00569 4.6e-24
JNHNGPDM_00570 4.6e-58
JNHNGPDM_00571 2.2e-116
JNHNGPDM_00572 4.9e-75
JNHNGPDM_00573 7.2e-62 S Bacteriophage HK97-gp10, putative tail-component
JNHNGPDM_00574 2.5e-39 S Phage head-tail joining protein
JNHNGPDM_00575 1.1e-63 S Phage gp6-like head-tail connector protein
JNHNGPDM_00576 5.9e-208 S Phage capsid family
JNHNGPDM_00577 2.4e-113 pi136 S Caudovirus prohead serine protease
JNHNGPDM_00578 2.6e-212 S Phage portal protein
JNHNGPDM_00580 0.0 terL S overlaps another CDS with the same product name
JNHNGPDM_00581 1.3e-76 terS L Phage terminase, small subunit
JNHNGPDM_00582 2.8e-154 L HNH nucleases
JNHNGPDM_00583 1.2e-08
JNHNGPDM_00585 1.9e-83 arpU S Phage transcriptional regulator, ArpU family
JNHNGPDM_00590 3.6e-129
JNHNGPDM_00591 1.3e-67
JNHNGPDM_00593 4.4e-123 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
JNHNGPDM_00594 2.2e-190 L Belongs to the 'phage' integrase family
JNHNGPDM_00595 5.3e-119 L DnaD domain protein
JNHNGPDM_00598 8e-15
JNHNGPDM_00602 2.8e-10 K Helix-turn-helix XRE-family like proteins
JNHNGPDM_00603 1.8e-79 3.4.21.88 K Peptidase S24-like
JNHNGPDM_00605 7e-16
JNHNGPDM_00608 6.5e-47
JNHNGPDM_00610 5.1e-223 3.6.4.12 L Belongs to the 'phage' integrase family
JNHNGPDM_00611 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JNHNGPDM_00612 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JNHNGPDM_00613 0.0 dnaK O Heat shock 70 kDa protein
JNHNGPDM_00614 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JNHNGPDM_00615 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JNHNGPDM_00616 5.8e-64
JNHNGPDM_00617 1.9e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JNHNGPDM_00618 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
JNHNGPDM_00619 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JNHNGPDM_00620 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JNHNGPDM_00621 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JNHNGPDM_00622 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JNHNGPDM_00623 1.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JNHNGPDM_00624 5.5e-217 patA 2.6.1.1 E Aminotransferase
JNHNGPDM_00625 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JNHNGPDM_00626 8.5e-84 KT Putative sugar diacid recognition
JNHNGPDM_00627 2.2e-219 EG GntP family permease
JNHNGPDM_00628 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JNHNGPDM_00629 7.7e-58
JNHNGPDM_00631 3.2e-134 mltD CBM50 M NlpC P60 family protein
JNHNGPDM_00632 5.7e-29
JNHNGPDM_00633 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
JNHNGPDM_00634 9.8e-32 ykzG S Belongs to the UPF0356 family
JNHNGPDM_00635 2.4e-78
JNHNGPDM_00636 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JNHNGPDM_00637 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JNHNGPDM_00638 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
JNHNGPDM_00639 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JNHNGPDM_00640 1.2e-274 lpdA 1.8.1.4 C Dehydrogenase
JNHNGPDM_00641 1.4e-47 yktA S Belongs to the UPF0223 family
JNHNGPDM_00642 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JNHNGPDM_00643 0.0 typA T GTP-binding protein TypA
JNHNGPDM_00644 3.5e-222 ftsW D Belongs to the SEDS family
JNHNGPDM_00645 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
JNHNGPDM_00646 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
JNHNGPDM_00647 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JNHNGPDM_00648 4.3e-197 ylbL T Belongs to the peptidase S16 family
JNHNGPDM_00649 2.6e-80 comEA L Competence protein ComEA
JNHNGPDM_00650 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
JNHNGPDM_00651 0.0 comEC S Competence protein ComEC
JNHNGPDM_00652 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
JNHNGPDM_00653 1.1e-34 rpsT J Binds directly to 16S ribosomal RNA
JNHNGPDM_00654 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JNHNGPDM_00655 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JNHNGPDM_00656 3.5e-163 S Tetratricopeptide repeat
JNHNGPDM_00657 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JNHNGPDM_00658 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JNHNGPDM_00659 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JNHNGPDM_00660 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
JNHNGPDM_00661 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
JNHNGPDM_00662 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JNHNGPDM_00663 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JNHNGPDM_00664 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JNHNGPDM_00665 2.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
JNHNGPDM_00666 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JNHNGPDM_00668 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JNHNGPDM_00669 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JNHNGPDM_00670 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
JNHNGPDM_00671 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
JNHNGPDM_00672 4.7e-243 codA 3.5.4.1 F cytosine deaminase
JNHNGPDM_00673 3.1e-147 tesE Q hydratase
JNHNGPDM_00674 4e-113 S (CBS) domain
JNHNGPDM_00675 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JNHNGPDM_00676 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JNHNGPDM_00677 8.1e-39 yabO J S4 domain protein
JNHNGPDM_00678 3.3e-56 divIC D Septum formation initiator
JNHNGPDM_00679 9.8e-67 yabR J RNA binding
JNHNGPDM_00680 7.2e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JNHNGPDM_00681 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JNHNGPDM_00682 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JNHNGPDM_00683 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JNHNGPDM_00684 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JNHNGPDM_00685 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JNHNGPDM_00686 5.5e-280 O Arylsulfotransferase (ASST)
JNHNGPDM_00687 4.9e-273 pipD E Dipeptidase
JNHNGPDM_00688 0.0 yjbQ P TrkA C-terminal domain protein
JNHNGPDM_00689 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JNHNGPDM_00690 1.5e-288 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JNHNGPDM_00691 2.9e-82
JNHNGPDM_00692 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
JNHNGPDM_00693 5.5e-40 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JNHNGPDM_00694 8.4e-156 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JNHNGPDM_00695 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
JNHNGPDM_00696 1.1e-90 bioY S BioY family
JNHNGPDM_00697 1.5e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JNHNGPDM_00698 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
JNHNGPDM_00699 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JNHNGPDM_00700 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JNHNGPDM_00701 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JNHNGPDM_00702 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
JNHNGPDM_00703 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JNHNGPDM_00704 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JNHNGPDM_00705 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JNHNGPDM_00706 1.9e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JNHNGPDM_00707 1.2e-219 patA 2.6.1.1 E Aminotransferase
JNHNGPDM_00708 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
JNHNGPDM_00709 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JNHNGPDM_00710 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JNHNGPDM_00711 3e-30 S Protein of unknown function (DUF2929)
JNHNGPDM_00712 0.0 dnaE 2.7.7.7 L DNA polymerase
JNHNGPDM_00713 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JNHNGPDM_00714 2.3e-167 cvfB S S1 domain
JNHNGPDM_00715 1.2e-163 xerD D recombinase XerD
JNHNGPDM_00716 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JNHNGPDM_00717 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JNHNGPDM_00718 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JNHNGPDM_00719 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JNHNGPDM_00720 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JNHNGPDM_00721 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
JNHNGPDM_00722 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
JNHNGPDM_00723 8.5e-14 M Lysin motif
JNHNGPDM_00724 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JNHNGPDM_00725 6.7e-205 rpsA 1.17.7.4 J Ribosomal protein S1
JNHNGPDM_00726 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JNHNGPDM_00727 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JNHNGPDM_00728 1.5e-236 S Tetratricopeptide repeat protein
JNHNGPDM_00729 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JNHNGPDM_00730 0.0 yfmR S ABC transporter, ATP-binding protein
JNHNGPDM_00731 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JNHNGPDM_00732 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JNHNGPDM_00733 5.3e-113 hlyIII S protein, hemolysin III
JNHNGPDM_00734 1.7e-151 DegV S EDD domain protein, DegV family
JNHNGPDM_00735 9.5e-172 ypmR E lipolytic protein G-D-S-L family
JNHNGPDM_00736 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
JNHNGPDM_00737 4.4e-35 yozE S Belongs to the UPF0346 family
JNHNGPDM_00738 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JNHNGPDM_00739 7.9e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JNHNGPDM_00740 2.4e-161 dprA LU DNA protecting protein DprA
JNHNGPDM_00741 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JNHNGPDM_00742 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
JNHNGPDM_00743 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JNHNGPDM_00744 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JNHNGPDM_00745 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JNHNGPDM_00746 1.7e-84 F NUDIX domain
JNHNGPDM_00747 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
JNHNGPDM_00748 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JNHNGPDM_00749 1.6e-105 ypsA S Belongs to the UPF0398 family
JNHNGPDM_00750 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JNHNGPDM_00751 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
JNHNGPDM_00752 2e-161 EG EamA-like transporter family
JNHNGPDM_00753 3e-125 dnaD L DnaD domain protein
JNHNGPDM_00754 2.9e-85 ypmB S Protein conserved in bacteria
JNHNGPDM_00755 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JNHNGPDM_00756 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JNHNGPDM_00757 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JNHNGPDM_00758 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
JNHNGPDM_00759 1.4e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JNHNGPDM_00760 3.8e-87 S Protein of unknown function (DUF1440)
JNHNGPDM_00761 0.0 rafA 3.2.1.22 G alpha-galactosidase
JNHNGPDM_00762 4.2e-189 galR K Periplasmic binding protein-like domain
JNHNGPDM_00763 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
JNHNGPDM_00764 9.3e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JNHNGPDM_00765 2.6e-124 lrgB M LrgB-like family
JNHNGPDM_00766 1.9e-66 lrgA S LrgA family
JNHNGPDM_00767 2.4e-130 lytT K response regulator receiver
JNHNGPDM_00768 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
JNHNGPDM_00769 4e-148 f42a O Band 7 protein
JNHNGPDM_00770 2.5e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JNHNGPDM_00771 6.4e-156 yitU 3.1.3.104 S hydrolase
JNHNGPDM_00772 9.2e-39 S Cytochrome B5
JNHNGPDM_00773 8.3e-114 nreC K PFAM regulatory protein LuxR
JNHNGPDM_00774 6.1e-160 hipB K Helix-turn-helix
JNHNGPDM_00775 2.8e-57 yitW S Iron-sulfur cluster assembly protein
JNHNGPDM_00776 1.6e-271 sufB O assembly protein SufB
JNHNGPDM_00777 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
JNHNGPDM_00778 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JNHNGPDM_00779 7.3e-239 sufD O FeS assembly protein SufD
JNHNGPDM_00780 6.5e-145 sufC O FeS assembly ATPase SufC
JNHNGPDM_00781 4.2e-32 feoA P FeoA domain
JNHNGPDM_00782 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
JNHNGPDM_00783 5.5e-19
JNHNGPDM_00784 4.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JNHNGPDM_00785 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JNHNGPDM_00786 3.5e-64 ydiI Q Thioesterase superfamily
JNHNGPDM_00787 2.4e-109 yvrI K sigma factor activity
JNHNGPDM_00788 5e-202 G Transporter, major facilitator family protein
JNHNGPDM_00789 0.0 S Bacterial membrane protein YfhO
JNHNGPDM_00790 4.7e-102 T Ion transport 2 domain protein
JNHNGPDM_00791 5.7e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JNHNGPDM_00792 1.9e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
JNHNGPDM_00793 7.3e-96 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
JNHNGPDM_00794 5e-185 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNHNGPDM_00795 9e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
JNHNGPDM_00796 7.4e-230 L transposase, IS605 OrfB family
JNHNGPDM_00797 2.1e-60 L PFAM transposase IS200-family protein
JNHNGPDM_00798 2e-48 L PFAM transposase IS200-family protein
JNHNGPDM_00799 8.8e-71 yneR S Belongs to the HesB IscA family
JNHNGPDM_00800 0.0 S membrane
JNHNGPDM_00801 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
JNHNGPDM_00802 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JNHNGPDM_00803 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JNHNGPDM_00804 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
JNHNGPDM_00805 1.4e-26 gluP 3.4.21.105 S Peptidase, S54 family
JNHNGPDM_00806 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
JNHNGPDM_00807 5.6e-183 glk 2.7.1.2 G Glucokinase
JNHNGPDM_00808 3.4e-67 yqhL P Rhodanese-like protein
JNHNGPDM_00809 1.3e-21 S Protein of unknown function (DUF3042)
JNHNGPDM_00810 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JNHNGPDM_00811 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
JNHNGPDM_00812 3.8e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JNHNGPDM_00813 6.3e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
JNHNGPDM_00814 3.9e-12
JNHNGPDM_00815 1.7e-146 P Belongs to the nlpA lipoprotein family
JNHNGPDM_00816 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JNHNGPDM_00817 3.7e-51 S Iron-sulfur cluster assembly protein
JNHNGPDM_00818 1e-151
JNHNGPDM_00819 6.6e-174
JNHNGPDM_00820 7.2e-89 dut S Protein conserved in bacteria
JNHNGPDM_00823 1.8e-110 K Transcriptional regulator
JNHNGPDM_00824 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
JNHNGPDM_00825 1.6e-54 ysxB J Cysteine protease Prp
JNHNGPDM_00826 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JNHNGPDM_00827 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JNHNGPDM_00828 5.1e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JNHNGPDM_00829 1.9e-113 J 2'-5' RNA ligase superfamily
JNHNGPDM_00830 2.2e-70 yqhY S Asp23 family, cell envelope-related function
JNHNGPDM_00831 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JNHNGPDM_00832 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JNHNGPDM_00833 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JNHNGPDM_00834 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JNHNGPDM_00835 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JNHNGPDM_00836 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JNHNGPDM_00837 8.1e-76 argR K Regulates arginine biosynthesis genes
JNHNGPDM_00838 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
JNHNGPDM_00839 2.4e-53
JNHNGPDM_00840 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JNHNGPDM_00841 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JNHNGPDM_00842 1.2e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JNHNGPDM_00843 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JNHNGPDM_00844 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JNHNGPDM_00845 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JNHNGPDM_00846 3.8e-131 stp 3.1.3.16 T phosphatase
JNHNGPDM_00847 0.0 KLT serine threonine protein kinase
JNHNGPDM_00848 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JNHNGPDM_00849 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JNHNGPDM_00850 1.6e-114 thiN 2.7.6.2 H thiamine pyrophosphokinase
JNHNGPDM_00851 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JNHNGPDM_00852 4.7e-58 asp S Asp23 family, cell envelope-related function
JNHNGPDM_00853 7.1e-311 yloV S DAK2 domain fusion protein YloV
JNHNGPDM_00854 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JNHNGPDM_00855 6.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JNHNGPDM_00856 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JNHNGPDM_00857 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JNHNGPDM_00858 0.0 smc D Required for chromosome condensation and partitioning
JNHNGPDM_00859 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JNHNGPDM_00860 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JNHNGPDM_00861 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JNHNGPDM_00862 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JNHNGPDM_00863 1.3e-38 ylqC S Belongs to the UPF0109 family
JNHNGPDM_00864 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JNHNGPDM_00865 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JNHNGPDM_00866 9.9e-261 yfnA E amino acid
JNHNGPDM_00867 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JNHNGPDM_00868 2.9e-34
JNHNGPDM_00869 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
JNHNGPDM_00870 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
JNHNGPDM_00871 3.3e-83
JNHNGPDM_00872 5.9e-114 L PFAM Integrase catalytic region
JNHNGPDM_00873 2.1e-60 L PFAM transposase IS200-family protein
JNHNGPDM_00874 7.4e-230 L transposase, IS605 OrfB family
JNHNGPDM_00875 1.9e-34 T Toxin-antitoxin system, toxin component, MazF family
JNHNGPDM_00876 8.9e-37
JNHNGPDM_00877 6.7e-07 D nuclear chromosome segregation
JNHNGPDM_00878 0.0 snf 2.7.11.1 KL domain protein
JNHNGPDM_00879 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
JNHNGPDM_00880 1e-170 M Glycosyl hydrolases family 25
JNHNGPDM_00881 6.4e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JNHNGPDM_00882 0.0 sbcC L Putative exonuclease SbcCD, C subunit
JNHNGPDM_00883 7.4e-230 L transposase, IS605 OrfB family
JNHNGPDM_00884 2.1e-60 L PFAM transposase IS200-family protein
JNHNGPDM_00886 0.0 L PLD-like domain
JNHNGPDM_00887 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
JNHNGPDM_00888 4.3e-61 3.1.21.3 V type I restriction modification DNA specificity domain
JNHNGPDM_00889 2.1e-177 xerC L Belongs to the 'phage' integrase family
JNHNGPDM_00890 1.4e-39 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction
JNHNGPDM_00891 1.1e-26 3.1.21.3 V Type I restriction modification DNA specificity domain
JNHNGPDM_00892 6.1e-301 2.1.1.72 V type I restriction-modification system
JNHNGPDM_00893 4.1e-57 yhaI S Protein of unknown function (DUF805)
JNHNGPDM_00894 2.2e-44
JNHNGPDM_00895 2.4e-22
JNHNGPDM_00896 5.4e-47
JNHNGPDM_00897 2.9e-96 K Acetyltransferase (GNAT) domain
JNHNGPDM_00898 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
JNHNGPDM_00899 3e-39 gntT EG Gluconate
JNHNGPDM_00900 4.9e-160 gntT EG Gluconate
JNHNGPDM_00901 9.9e-183 K Transcriptional regulator, LacI family
JNHNGPDM_00902 7e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
JNHNGPDM_00903 3.2e-95
JNHNGPDM_00904 2.1e-25
JNHNGPDM_00905 1.3e-61 asp S Asp23 family, cell envelope-related function
JNHNGPDM_00906 3.5e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
JNHNGPDM_00908 2.7e-49
JNHNGPDM_00909 1.6e-67 yqkB S Belongs to the HesB IscA family
JNHNGPDM_00910 5.9e-114 L PFAM Integrase catalytic region
JNHNGPDM_00911 7.4e-230 L transposase, IS605 OrfB family
JNHNGPDM_00912 2.1e-60 L PFAM transposase IS200-family protein
JNHNGPDM_00914 3.4e-250 mmuP E amino acid
JNHNGPDM_00915 2e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
JNHNGPDM_00916 1e-44
JNHNGPDM_00918 1.8e-09
JNHNGPDM_00919 4.4e-100 L Helix-turn-helix domain
JNHNGPDM_00920 4.5e-160 L hmm pf00665
JNHNGPDM_00921 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JNHNGPDM_00922 3e-34
JNHNGPDM_00923 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
JNHNGPDM_00924 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
JNHNGPDM_00925 7.5e-86 ygfC K transcriptional regulator (TetR family)
JNHNGPDM_00926 2.1e-183 hrtB V ABC transporter permease
JNHNGPDM_00927 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
JNHNGPDM_00928 0.0 yhcA V ABC transporter, ATP-binding protein
JNHNGPDM_00929 4.6e-38
JNHNGPDM_00930 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JNHNGPDM_00931 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
JNHNGPDM_00932 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JNHNGPDM_00933 2.4e-223 mdtG EGP Major facilitator Superfamily
JNHNGPDM_00934 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
JNHNGPDM_00935 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JNHNGPDM_00938 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
JNHNGPDM_00939 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
JNHNGPDM_00940 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
JNHNGPDM_00941 0.0 trxB2 1.8.1.9 C Thioredoxin domain
JNHNGPDM_00942 0.0 csd1 3.5.1.28 G domain, Protein
JNHNGPDM_00943 0.0 2.7.7.6 M Peptidase family M23
JNHNGPDM_00944 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
JNHNGPDM_00945 2.4e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
JNHNGPDM_00946 3.3e-146 cps1D M Domain of unknown function (DUF4422)
JNHNGPDM_00947 7.9e-127 recX 2.4.1.337 GT4 S Regulatory protein RecX
JNHNGPDM_00948 4.9e-31
JNHNGPDM_00949 6.6e-34 S Protein of unknown function (DUF2922)
JNHNGPDM_00950 3.2e-153 yihY S Belongs to the UPF0761 family
JNHNGPDM_00951 1.1e-281 yjeM E Amino Acid
JNHNGPDM_00952 1e-254 E Arginine ornithine antiporter
JNHNGPDM_00953 1.7e-220 arcT 2.6.1.1 E Aminotransferase
JNHNGPDM_00954 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
JNHNGPDM_00955 6.1e-79 fld C Flavodoxin
JNHNGPDM_00956 2.3e-67 gtcA S Teichoic acid glycosylation protein
JNHNGPDM_00957 9.3e-56
JNHNGPDM_00958 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JNHNGPDM_00960 2.6e-228 yfmL L DEAD DEAH box helicase
JNHNGPDM_00961 4.5e-191 mocA S Oxidoreductase
JNHNGPDM_00962 9.1e-62 S Domain of unknown function (DUF4828)
JNHNGPDM_00963 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
JNHNGPDM_00964 3.8e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JNHNGPDM_00965 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
JNHNGPDM_00966 9.3e-197 S Protein of unknown function (DUF3114)
JNHNGPDM_00967 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
JNHNGPDM_00968 1.1e-119 ybhL S Belongs to the BI1 family
JNHNGPDM_00969 3.1e-21
JNHNGPDM_00970 1.4e-95 K Acetyltransferase (GNAT) family
JNHNGPDM_00971 1e-75 K LytTr DNA-binding domain
JNHNGPDM_00972 7.3e-69 S Protein of unknown function (DUF3021)
JNHNGPDM_00973 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
JNHNGPDM_00974 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
JNHNGPDM_00975 2.6e-74 ogt 2.1.1.63 L Methyltransferase
JNHNGPDM_00976 4.8e-122 pnb C nitroreductase
JNHNGPDM_00977 2.1e-91
JNHNGPDM_00978 1.4e-90 S B3 4 domain
JNHNGPDM_00979 4e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
JNHNGPDM_00980 1.5e-156 amtB P ammonium transporter
JNHNGPDM_00981 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JNHNGPDM_00983 1.3e-46
JNHNGPDM_00984 3.2e-96 S PFAM Archaeal ATPase
JNHNGPDM_00985 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JNHNGPDM_00986 9.7e-173
JNHNGPDM_00987 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JNHNGPDM_00988 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
JNHNGPDM_00989 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JNHNGPDM_00990 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JNHNGPDM_00991 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JNHNGPDM_00992 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JNHNGPDM_00993 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JNHNGPDM_00994 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JNHNGPDM_00995 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JNHNGPDM_00996 9.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JNHNGPDM_00997 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JNHNGPDM_00998 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JNHNGPDM_00999 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JNHNGPDM_01000 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
JNHNGPDM_01001 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JNHNGPDM_01002 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JNHNGPDM_01003 4.9e-177 K AI-2E family transporter
JNHNGPDM_01004 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JNHNGPDM_01005 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNHNGPDM_01006 5.1e-116 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
JNHNGPDM_01007 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JNHNGPDM_01008 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JNHNGPDM_01009 3.3e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JNHNGPDM_01010 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JNHNGPDM_01011 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JNHNGPDM_01012 7.4e-134 K LysR substrate binding domain
JNHNGPDM_01013 2e-48 L PFAM transposase IS200-family protein
JNHNGPDM_01014 2.1e-55 S Protein of unknown function (DUF3290)
JNHNGPDM_01015 6.9e-113 yviA S Protein of unknown function (DUF421)
JNHNGPDM_01016 4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
JNHNGPDM_01017 1.3e-20
JNHNGPDM_01018 8.1e-90 ntd 2.4.2.6 F Nucleoside
JNHNGPDM_01019 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
JNHNGPDM_01020 1.6e-45 yrvD S Pfam:DUF1049
JNHNGPDM_01022 1.1e-35 S Phage derived protein Gp49-like (DUF891)
JNHNGPDM_01023 8.5e-20 K Helix-turn-helix XRE-family like proteins
JNHNGPDM_01024 1.7e-78 I alpha/beta hydrolase fold
JNHNGPDM_01025 1.1e-113 frnE Q DSBA-like thioredoxin domain
JNHNGPDM_01026 2e-53
JNHNGPDM_01027 9.3e-189 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JNHNGPDM_01028 4e-28 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JNHNGPDM_01029 3.2e-125 S Putative adhesin
JNHNGPDM_01030 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
JNHNGPDM_01031 4e-56 K transcriptional regulator PadR family
JNHNGPDM_01032 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JNHNGPDM_01034 1.2e-230 L Integrase core domain
JNHNGPDM_01035 5.1e-139 L Bacterial dnaA protein
JNHNGPDM_01036 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JNHNGPDM_01037 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JNHNGPDM_01038 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JNHNGPDM_01039 9.6e-247 M Glycosyl transferase family group 2
JNHNGPDM_01041 1.3e-226 aadAT EK Aminotransferase, class I
JNHNGPDM_01042 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JNHNGPDM_01043 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JNHNGPDM_01044 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
JNHNGPDM_01045 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JNHNGPDM_01046 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JNHNGPDM_01047 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JNHNGPDM_01048 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JNHNGPDM_01049 1.9e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JNHNGPDM_01050 1.7e-207 yacL S domain protein
JNHNGPDM_01051 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JNHNGPDM_01052 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
JNHNGPDM_01053 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
JNHNGPDM_01054 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JNHNGPDM_01055 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
JNHNGPDM_01056 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JNHNGPDM_01057 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JNHNGPDM_01058 2.4e-119 tcyB E ABC transporter
JNHNGPDM_01059 1.2e-213 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JNHNGPDM_01060 3.1e-169 I alpha/beta hydrolase fold
JNHNGPDM_01061 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JNHNGPDM_01062 0.0 S Bacterial membrane protein, YfhO
JNHNGPDM_01063 2.7e-182 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
JNHNGPDM_01064 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
JNHNGPDM_01066 1.7e-81 ydcK S Belongs to the SprT family
JNHNGPDM_01067 0.0 yhgF K Tex-like protein N-terminal domain protein
JNHNGPDM_01068 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JNHNGPDM_01069 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JNHNGPDM_01070 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
JNHNGPDM_01071 2.4e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JNHNGPDM_01072 1.8e-298 aspT P Predicted Permease Membrane Region
JNHNGPDM_01073 2.8e-252 EGP Major facilitator Superfamily
JNHNGPDM_01074 5.5e-110
JNHNGPDM_01077 1.4e-158 yjjH S Calcineurin-like phosphoesterase
JNHNGPDM_01078 5e-263 dtpT U amino acid peptide transporter
JNHNGPDM_01079 3.7e-19
JNHNGPDM_01081 3.7e-91 yqiG C Oxidoreductase
JNHNGPDM_01082 3.7e-84 yqiG C Oxidoreductase
JNHNGPDM_01083 8.5e-54 S macrophage migration inhibitory factor
JNHNGPDM_01084 2.4e-65 K HxlR-like helix-turn-helix
JNHNGPDM_01085 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JNHNGPDM_01087 1.9e-225 L Transposase IS66 family
JNHNGPDM_01088 5.9e-114 L PFAM Integrase catalytic region
JNHNGPDM_01089 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
JNHNGPDM_01090 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
JNHNGPDM_01091 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
JNHNGPDM_01092 2e-92 folT S ECF transporter, substrate-specific component
JNHNGPDM_01093 0.0 pepN 3.4.11.2 E aminopeptidase
JNHNGPDM_01094 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
JNHNGPDM_01095 9.8e-255 pepC 3.4.22.40 E aminopeptidase
JNHNGPDM_01096 6.5e-210 EGP Major facilitator Superfamily
JNHNGPDM_01097 2.4e-229
JNHNGPDM_01098 7.8e-79 K Transcriptional regulator, HxlR family
JNHNGPDM_01099 3.7e-108 XK27_02070 S Nitroreductase family
JNHNGPDM_01100 2.5e-52 hxlR K Transcriptional regulator, HxlR family
JNHNGPDM_01101 3e-119 GM NmrA-like family
JNHNGPDM_01102 1.7e-70 elaA S Gnat family
JNHNGPDM_01103 1.8e-39 S Cytochrome B5
JNHNGPDM_01104 5.4e-09 S Cytochrome B5
JNHNGPDM_01105 7.8e-41 S Cytochrome B5
JNHNGPDM_01106 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
JNHNGPDM_01108 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JNHNGPDM_01109 1.1e-240 E amino acid
JNHNGPDM_01110 2.8e-215 npp S type I phosphodiesterase nucleotide pyrophosphatase
JNHNGPDM_01111 3.1e-226 yxiO S Vacuole effluxer Atg22 like
JNHNGPDM_01113 4.4e-100 L Helix-turn-helix domain
JNHNGPDM_01114 4.5e-160 L hmm pf00665
JNHNGPDM_01126 4.3e-83 usp6 T universal stress protein
JNHNGPDM_01127 1.7e-45
JNHNGPDM_01128 1.7e-235 rarA L recombination factor protein RarA
JNHNGPDM_01129 7.1e-86 yueI S Protein of unknown function (DUF1694)
JNHNGPDM_01130 1.5e-21
JNHNGPDM_01131 8.1e-75 4.4.1.5 E Glyoxalase
JNHNGPDM_01132 2.5e-138 S Membrane
JNHNGPDM_01133 2.5e-135 S Belongs to the UPF0246 family
JNHNGPDM_01134 1.1e-206 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
JNHNGPDM_01135 8.2e-93 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
JNHNGPDM_01136 4.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
JNHNGPDM_01137 1.1e-235 pbuG S permease
JNHNGPDM_01138 1.3e-262 L Transposase
JNHNGPDM_01139 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JNHNGPDM_01140 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JNHNGPDM_01141 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
JNHNGPDM_01142 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNHNGPDM_01143 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JNHNGPDM_01144 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
JNHNGPDM_01145 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
JNHNGPDM_01146 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
JNHNGPDM_01147 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JNHNGPDM_01148 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
JNHNGPDM_01149 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JNHNGPDM_01150 6.8e-121 radC L DNA repair protein
JNHNGPDM_01151 1.7e-179 mreB D cell shape determining protein MreB
JNHNGPDM_01152 8.5e-151 mreC M Involved in formation and maintenance of cell shape
JNHNGPDM_01153 1.2e-91 mreD M rod shape-determining protein MreD
JNHNGPDM_01154 3.2e-102 glnP P ABC transporter permease
JNHNGPDM_01155 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JNHNGPDM_01156 2.6e-160 aatB ET ABC transporter substrate-binding protein
JNHNGPDM_01157 1.6e-230 ymfF S Peptidase M16 inactive domain protein
JNHNGPDM_01158 6e-249 ymfH S Peptidase M16
JNHNGPDM_01159 7.4e-141 ymfM S Helix-turn-helix domain
JNHNGPDM_01160 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JNHNGPDM_01161 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
JNHNGPDM_01162 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JNHNGPDM_01163 1.1e-163 yueF S AI-2E family transporter
JNHNGPDM_01164 6.9e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JNHNGPDM_01165 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JNHNGPDM_01166 2.2e-34 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
JNHNGPDM_01167 4.7e-217 M NlpC/P60 family
JNHNGPDM_01168 1.2e-174 M NlpC/P60 family
JNHNGPDM_01169 7e-55 M NlpC/P60 family
JNHNGPDM_01170 0.0 S Peptidase, M23
JNHNGPDM_01171 0.0 bamA GM domain, Protein
JNHNGPDM_01172 7.9e-64 gntR1 K Transcriptional regulator, GntR family
JNHNGPDM_01173 1e-156 V ABC transporter, ATP-binding protein
JNHNGPDM_01174 6.7e-114
JNHNGPDM_01175 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
JNHNGPDM_01176 2.4e-99 S Pfam:DUF3816
JNHNGPDM_01177 0.0 clpE O Belongs to the ClpA ClpB family
JNHNGPDM_01178 2.9e-27
JNHNGPDM_01179 2.7e-39 ptsH G phosphocarrier protein HPR
JNHNGPDM_01180 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JNHNGPDM_01181 6.7e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JNHNGPDM_01182 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
JNHNGPDM_01183 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JNHNGPDM_01184 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
JNHNGPDM_01185 4.1e-37 S Uncharacterised protein family (UPF0236)
JNHNGPDM_01186 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JNHNGPDM_01187 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JNHNGPDM_01188 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JNHNGPDM_01189 3e-203 coiA 3.6.4.12 S Competence protein
JNHNGPDM_01190 9.2e-264 pipD E Dipeptidase
JNHNGPDM_01191 4.7e-114 yjbH Q Thioredoxin
JNHNGPDM_01192 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
JNHNGPDM_01193 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JNHNGPDM_01194 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
JNHNGPDM_01195 4.5e-160 L hmm pf00665
JNHNGPDM_01196 4.4e-100 L Helix-turn-helix domain
JNHNGPDM_01198 5.9e-191 V Beta-lactamase
JNHNGPDM_01199 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JNHNGPDM_01200 5e-122 yhiD S MgtC family
JNHNGPDM_01201 6.4e-39 S GyrI-like small molecule binding domain
JNHNGPDM_01202 2.7e-70 S GyrI-like small molecule binding domain
JNHNGPDM_01204 6.1e-117 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
JNHNGPDM_01205 7.1e-50 azlD E Branched-chain amino acid transport
JNHNGPDM_01206 1.4e-119 azlC E azaleucine resistance protein AzlC
JNHNGPDM_01207 7.3e-60 K Aminotransferase class I and II
JNHNGPDM_01208 5.9e-152 K Aminotransferase class I and II
JNHNGPDM_01209 3.6e-288 S amidohydrolase
JNHNGPDM_01211 1.8e-161 S reductase
JNHNGPDM_01212 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
JNHNGPDM_01213 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JNHNGPDM_01214 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
JNHNGPDM_01215 1.5e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JNHNGPDM_01216 0.0 asnB 6.3.5.4 E Asparagine synthase
JNHNGPDM_01217 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JNHNGPDM_01218 8.7e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JNHNGPDM_01219 9.7e-130 jag S R3H domain protein
JNHNGPDM_01220 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JNHNGPDM_01221 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JNHNGPDM_01222 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
JNHNGPDM_01223 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JNHNGPDM_01224 9.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JNHNGPDM_01225 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
JNHNGPDM_01226 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
JNHNGPDM_01227 1.7e-34 yaaA S S4 domain protein YaaA
JNHNGPDM_01228 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JNHNGPDM_01229 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JNHNGPDM_01230 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JNHNGPDM_01231 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
JNHNGPDM_01232 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JNHNGPDM_01233 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JNHNGPDM_01234 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JNHNGPDM_01235 2e-74 rplI J Binds to the 23S rRNA
JNHNGPDM_01236 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JNHNGPDM_01237 9.9e-206 yttB EGP Major facilitator Superfamily
JNHNGPDM_01238 3.7e-54
JNHNGPDM_01239 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
JNHNGPDM_01240 9.8e-09 K DNA-binding helix-turn-helix protein
JNHNGPDM_01241 2.3e-78 O Bacterial dnaA protein
JNHNGPDM_01242 4.1e-37 S Uncharacterised protein family (UPF0236)
JNHNGPDM_01244 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JNHNGPDM_01245 0.0 helD 3.6.4.12 L DNA helicase
JNHNGPDM_01246 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
JNHNGPDM_01247 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
JNHNGPDM_01248 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
JNHNGPDM_01249 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JNHNGPDM_01250 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JNHNGPDM_01251 1.6e-177
JNHNGPDM_01252 1e-130 cobB K SIR2 family
JNHNGPDM_01254 3.6e-162 yunF F Protein of unknown function DUF72
JNHNGPDM_01255 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNHNGPDM_01256 1.9e-155 tatD L hydrolase, TatD family
JNHNGPDM_01257 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JNHNGPDM_01258 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JNHNGPDM_01259 6.8e-37 veg S Biofilm formation stimulator VEG
JNHNGPDM_01260 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JNHNGPDM_01261 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
JNHNGPDM_01262 2.2e-122 fhuC P ABC transporter
JNHNGPDM_01263 1.4e-118 znuB U ABC 3 transport family
JNHNGPDM_01264 2.6e-149 purR 2.4.2.7 F pur operon repressor
JNHNGPDM_01265 3.4e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JNHNGPDM_01266 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JNHNGPDM_01267 2.1e-49
JNHNGPDM_01268 2.5e-147 yxeH S hydrolase
JNHNGPDM_01269 5e-270 ywfO S HD domain protein
JNHNGPDM_01270 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
JNHNGPDM_01271 3e-66 ywiB S Domain of unknown function (DUF1934)
JNHNGPDM_01272 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JNHNGPDM_01273 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JNHNGPDM_01274 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JNHNGPDM_01275 4.6e-41 rpmE2 J Ribosomal protein L31
JNHNGPDM_01276 1.8e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JNHNGPDM_01277 1.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
JNHNGPDM_01278 5.1e-125 srtA 3.4.22.70 M sortase family
JNHNGPDM_01279 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
JNHNGPDM_01280 4.4e-157 3.2.1.55 GH51 G Right handed beta helix region
JNHNGPDM_01281 4e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JNHNGPDM_01282 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
JNHNGPDM_01283 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
JNHNGPDM_01284 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JNHNGPDM_01285 7e-93 lemA S LemA family
JNHNGPDM_01286 2.6e-158 htpX O Belongs to the peptidase M48B family
JNHNGPDM_01287 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JNHNGPDM_01288 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JNHNGPDM_01289 1.1e-126 L PFAM Integrase catalytic region
JNHNGPDM_01290 5e-141 sprD D Domain of Unknown Function (DUF1542)
JNHNGPDM_01291 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
JNHNGPDM_01292 3.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JNHNGPDM_01293 1e-265 yfnA E amino acid
JNHNGPDM_01294 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JNHNGPDM_01295 5.8e-40 1.3.5.4 S FMN binding
JNHNGPDM_01296 3.7e-221 norA EGP Major facilitator Superfamily
JNHNGPDM_01297 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JNHNGPDM_01298 4.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
JNHNGPDM_01299 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JNHNGPDM_01300 3.1e-103 metI P ABC transporter permease
JNHNGPDM_01301 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JNHNGPDM_01302 1.3e-251 clcA P chloride
JNHNGPDM_01303 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JNHNGPDM_01304 4.5e-104 proW P ABC transporter, permease protein
JNHNGPDM_01305 1e-139 proV E ABC transporter, ATP-binding protein
JNHNGPDM_01306 6.3e-109 proWZ P ABC transporter permease
JNHNGPDM_01307 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
JNHNGPDM_01308 9e-75 K Transcriptional regulator
JNHNGPDM_01309 4.8e-154 1.6.5.2 GM NAD(P)H-binding
JNHNGPDM_01311 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
JNHNGPDM_01312 0.0 cadA P P-type ATPase
JNHNGPDM_01313 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
JNHNGPDM_01314 2.1e-126
JNHNGPDM_01315 3.3e-55 S Sugar efflux transporter for intercellular exchange
JNHNGPDM_01316 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
JNHNGPDM_01318 0.0 L Helicase C-terminal domain protein
JNHNGPDM_01319 6.9e-76 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
JNHNGPDM_01320 2.2e-176 S Aldo keto reductase
JNHNGPDM_01321 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JNHNGPDM_01322 0.0 S SEC-C Motif Domain Protein
JNHNGPDM_01323 5.2e-50
JNHNGPDM_01324 6.7e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JNHNGPDM_01325 8.3e-22 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JNHNGPDM_01326 4.7e-85 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JNHNGPDM_01327 4.4e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JNHNGPDM_01328 1.8e-226 clcA_2 P Chloride transporter, ClC family
JNHNGPDM_01329 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
JNHNGPDM_01330 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
JNHNGPDM_01332 8.8e-77 yphH S Cupin domain
JNHNGPDM_01333 4.2e-72 yeaL S UPF0756 membrane protein
JNHNGPDM_01334 6.9e-243 EGP Major facilitator Superfamily
JNHNGPDM_01335 5e-75 copY K Copper transport repressor CopY TcrY
JNHNGPDM_01336 8.5e-246 yhdP S Transporter associated domain
JNHNGPDM_01337 0.0 ubiB S ABC1 family
JNHNGPDM_01338 9.6e-144 S DUF218 domain
JNHNGPDM_01339 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JNHNGPDM_01340 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JNHNGPDM_01341 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JNHNGPDM_01342 0.0 uvrA3 L excinuclease ABC, A subunit
JNHNGPDM_01343 4.6e-123 S SNARE associated Golgi protein
JNHNGPDM_01344 1.3e-229 N Uncharacterized conserved protein (DUF2075)
JNHNGPDM_01345 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JNHNGPDM_01347 1e-254 yifK E Amino acid permease
JNHNGPDM_01348 5.5e-158 endA V DNA/RNA non-specific endonuclease
JNHNGPDM_01349 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNHNGPDM_01350 5e-75 osmC O OsmC-like protein
JNHNGPDM_01351 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNHNGPDM_01352 1.8e-215 patA 2.6.1.1 E Aminotransferase
JNHNGPDM_01353 7.8e-32
JNHNGPDM_01354 0.0 clpL O associated with various cellular activities
JNHNGPDM_01356 9.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
JNHNGPDM_01357 6.1e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNHNGPDM_01358 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
JNHNGPDM_01359 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JNHNGPDM_01360 1.5e-172 malR K Transcriptional regulator, LacI family
JNHNGPDM_01361 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
JNHNGPDM_01362 1.1e-256 malT G Major Facilitator
JNHNGPDM_01363 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
JNHNGPDM_01364 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
JNHNGPDM_01365 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
JNHNGPDM_01366 3.3e-118 K response regulator
JNHNGPDM_01367 5.3e-226 sptS 2.7.13.3 T Histidine kinase
JNHNGPDM_01368 2.5e-209 yfeO P Voltage gated chloride channel
JNHNGPDM_01369 8.9e-256 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
JNHNGPDM_01370 6.6e-136 puuD S peptidase C26
JNHNGPDM_01371 3.8e-167 yvgN C Aldo keto reductase
JNHNGPDM_01372 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
JNHNGPDM_01373 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
JNHNGPDM_01374 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
JNHNGPDM_01375 4.2e-261 nox C NADH oxidase
JNHNGPDM_01376 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JNHNGPDM_01377 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JNHNGPDM_01378 3e-86
JNHNGPDM_01379 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JNHNGPDM_01381 1.1e-158 spoU 2.1.1.185 J Methyltransferase
JNHNGPDM_01382 4.9e-224 oxlT P Major Facilitator Superfamily
JNHNGPDM_01383 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JNHNGPDM_01385 1.5e-225 S cog cog1373
JNHNGPDM_01386 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
JNHNGPDM_01387 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JNHNGPDM_01388 4.7e-157 EG EamA-like transporter family
JNHNGPDM_01389 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
JNHNGPDM_01390 0.0 helD 3.6.4.12 L DNA helicase
JNHNGPDM_01391 3.4e-115 dedA S SNARE associated Golgi protein
JNHNGPDM_01392 4.2e-126 3.1.3.73 G phosphoglycerate mutase
JNHNGPDM_01393 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JNHNGPDM_01394 6.6e-35 S Transglycosylase associated protein
JNHNGPDM_01396 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNHNGPDM_01397 3.2e-226 V domain protein
JNHNGPDM_01398 1.6e-94 K Transcriptional regulator (TetR family)
JNHNGPDM_01399 9.8e-39 pspC KT positive regulation of macromolecule biosynthetic process
JNHNGPDM_01400 2e-152
JNHNGPDM_01401 4e-17 3.2.1.14 GH18
JNHNGPDM_01402 1.5e-82 zur P Belongs to the Fur family
JNHNGPDM_01403 5.8e-103 gmk2 2.7.4.8 F Guanylate kinase
JNHNGPDM_01404 2.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
JNHNGPDM_01405 3e-254 yfnA E Amino Acid
JNHNGPDM_01406 3.6e-233 EGP Sugar (and other) transporter
JNHNGPDM_01407 3.7e-43
JNHNGPDM_01408 1.8e-108
JNHNGPDM_01409 4.7e-207 potD P ABC transporter
JNHNGPDM_01410 4.9e-140 potC P ABC transporter permease
JNHNGPDM_01411 4.5e-146 potB P ABC transporter permease
JNHNGPDM_01412 1.7e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JNHNGPDM_01413 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JNHNGPDM_01414 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
JNHNGPDM_01415 0.0 pacL 3.6.3.8 P P-type ATPase
JNHNGPDM_01416 3.4e-85 dps P Belongs to the Dps family
JNHNGPDM_01417 2.8e-255 yagE E amino acid
JNHNGPDM_01418 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
JNHNGPDM_01419 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JNHNGPDM_01420 2.7e-149 L hmm pf00665
JNHNGPDM_01421 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
JNHNGPDM_01422 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
JNHNGPDM_01423 2.5e-138 IQ KR domain
JNHNGPDM_01424 5.6e-133 S membrane transporter protein
JNHNGPDM_01425 3e-96 S ABC-type cobalt transport system, permease component
JNHNGPDM_01426 1e-246 cbiO1 S ABC transporter, ATP-binding protein
JNHNGPDM_01427 4.5e-112 P Cobalt transport protein
JNHNGPDM_01428 1.6e-52 yvlA
JNHNGPDM_01429 0.0 yjcE P Sodium proton antiporter
JNHNGPDM_01430 2.2e-52 ypaA S Protein of unknown function (DUF1304)
JNHNGPDM_01431 8.2e-190 D Alpha beta
JNHNGPDM_01432 1e-72 K Transcriptional regulator
JNHNGPDM_01433 1.1e-161
JNHNGPDM_01434 2.4e-167 1.6.5.5 C Zinc-binding dehydrogenase
JNHNGPDM_01435 1.3e-257 G PTS system Galactitol-specific IIC component
JNHNGPDM_01436 1.4e-212 EGP Major facilitator Superfamily
JNHNGPDM_01437 5.2e-14
JNHNGPDM_01438 7.1e-63
JNHNGPDM_01439 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
JNHNGPDM_01440 5.1e-81 uspA T universal stress protein
JNHNGPDM_01441 0.0 tetP J elongation factor G
JNHNGPDM_01442 5.2e-167 GK ROK family
JNHNGPDM_01443 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
JNHNGPDM_01444 4.5e-140 aroD S Serine hydrolase (FSH1)
JNHNGPDM_01445 2.7e-244 yagE E amino acid
JNHNGPDM_01446 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
JNHNGPDM_01447 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
JNHNGPDM_01448 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JNHNGPDM_01449 1.1e-283 pipD E Dipeptidase
JNHNGPDM_01450 0.0 yfiC V ABC transporter
JNHNGPDM_01451 2.4e-309 lmrA V ABC transporter, ATP-binding protein
JNHNGPDM_01452 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNHNGPDM_01453 6e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JNHNGPDM_01456 4.3e-25 UW LPXTG-motif cell wall anchor domain protein
JNHNGPDM_01457 8.2e-274 arcD S C4-dicarboxylate anaerobic carrier
JNHNGPDM_01458 2.6e-255 ytjP 3.5.1.18 E Dipeptidase
JNHNGPDM_01459 5.3e-215 uhpT EGP Major facilitator Superfamily
JNHNGPDM_01460 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
JNHNGPDM_01461 4.8e-132 ponA V Beta-lactamase enzyme family
JNHNGPDM_01462 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
JNHNGPDM_01463 6.7e-93 dps P Belongs to the Dps family
JNHNGPDM_01464 7.9e-35 copZ C Heavy-metal-associated domain
JNHNGPDM_01465 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
JNHNGPDM_01466 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JNHNGPDM_01467 7.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
JNHNGPDM_01468 8.1e-114 rlpA M PFAM NLP P60 protein
JNHNGPDM_01469 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JNHNGPDM_01470 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JNHNGPDM_01471 2e-58 yodB K Transcriptional regulator, HxlR family
JNHNGPDM_01472 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
JNHNGPDM_01473 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JNHNGPDM_01474 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JNHNGPDM_01475 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JNHNGPDM_01476 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JNHNGPDM_01477 4.4e-231 V MatE
JNHNGPDM_01478 7.4e-267 yjeM E Amino Acid
JNHNGPDM_01479 4.1e-278 arlS 2.7.13.3 T Histidine kinase
JNHNGPDM_01480 1.5e-121 K response regulator
JNHNGPDM_01481 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JNHNGPDM_01482 2.9e-99 yceD S Uncharacterized ACR, COG1399
JNHNGPDM_01483 6.1e-213 ylbM S Belongs to the UPF0348 family
JNHNGPDM_01484 1.7e-139 yqeM Q Methyltransferase
JNHNGPDM_01485 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JNHNGPDM_01486 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
JNHNGPDM_01487 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JNHNGPDM_01488 1.9e-47 yhbY J RNA-binding protein
JNHNGPDM_01489 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
JNHNGPDM_01490 1.8e-95 yqeG S HAD phosphatase, family IIIA
JNHNGPDM_01491 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JNHNGPDM_01492 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JNHNGPDM_01493 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JNHNGPDM_01494 1.1e-170 dnaI L Primosomal protein DnaI
JNHNGPDM_01495 1.4e-203 dnaB L replication initiation and membrane attachment
JNHNGPDM_01496 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JNHNGPDM_01497 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JNHNGPDM_01498 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JNHNGPDM_01499 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JNHNGPDM_01500 4.1e-116 yoaK S Protein of unknown function (DUF1275)
JNHNGPDM_01501 1.9e-119 ybhL S Belongs to the BI1 family
JNHNGPDM_01502 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JNHNGPDM_01503 1.5e-35 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
JNHNGPDM_01504 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
JNHNGPDM_01505 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JNHNGPDM_01506 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JNHNGPDM_01507 7.5e-58 ytzB S Small secreted protein
JNHNGPDM_01508 2.6e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
JNHNGPDM_01509 1.1e-183 iolS C Aldo keto reductase
JNHNGPDM_01510 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
JNHNGPDM_01511 6.7e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
JNHNGPDM_01512 4e-254 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
JNHNGPDM_01513 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
JNHNGPDM_01514 7.7e-27 S YSIRK type signal peptide
JNHNGPDM_01515 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JNHNGPDM_01516 5.1e-218 ecsB U ABC transporter
JNHNGPDM_01517 3.9e-136 ecsA V ABC transporter, ATP-binding protein
JNHNGPDM_01518 1.2e-76 hit FG histidine triad
JNHNGPDM_01520 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JNHNGPDM_01521 0.0 L AAA domain
JNHNGPDM_01522 1.8e-220 yhaO L Ser Thr phosphatase family protein
JNHNGPDM_01523 3.5e-40 yheA S Belongs to the UPF0342 family
JNHNGPDM_01524 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JNHNGPDM_01525 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JNHNGPDM_01526 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JNHNGPDM_01527 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JNHNGPDM_01529 3.3e-40
JNHNGPDM_01530 1.8e-43
JNHNGPDM_01531 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
JNHNGPDM_01532 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
JNHNGPDM_01533 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JNHNGPDM_01534 1.2e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
JNHNGPDM_01535 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
JNHNGPDM_01536 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JNHNGPDM_01538 1.9e-43
JNHNGPDM_01539 4.5e-112 S CAAX protease self-immunity
JNHNGPDM_01540 2.1e-32
JNHNGPDM_01541 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JNHNGPDM_01542 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
JNHNGPDM_01543 3.8e-113
JNHNGPDM_01544 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
JNHNGPDM_01545 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JNHNGPDM_01546 1.2e-85 uspA T Belongs to the universal stress protein A family
JNHNGPDM_01547 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
JNHNGPDM_01548 2.2e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JNHNGPDM_01549 9.2e-303 ytgP S Polysaccharide biosynthesis protein
JNHNGPDM_01550 4.9e-41
JNHNGPDM_01551 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JNHNGPDM_01552 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JNHNGPDM_01553 9.6e-92 tag 3.2.2.20 L glycosylase
JNHNGPDM_01554 3e-75
JNHNGPDM_01556 3.5e-49 czrA K Transcriptional regulator, ArsR family
JNHNGPDM_01557 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JNHNGPDM_01558 5.1e-173 scrR K Transcriptional regulator, LacI family
JNHNGPDM_01559 3e-24
JNHNGPDM_01560 8.2e-103
JNHNGPDM_01561 2.6e-214 yttB EGP Major facilitator Superfamily
JNHNGPDM_01562 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
JNHNGPDM_01563 2.2e-87
JNHNGPDM_01564 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
JNHNGPDM_01565 6.6e-262 S Putative peptidoglycan binding domain
JNHNGPDM_01566 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JNHNGPDM_01567 3.3e-46 gcvH E glycine cleavage
JNHNGPDM_01568 4.1e-220 rodA D Belongs to the SEDS family
JNHNGPDM_01569 1e-31 S Protein of unknown function (DUF2969)
JNHNGPDM_01570 1.9e-178 mbl D Cell shape determining protein MreB Mrl
JNHNGPDM_01571 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JNHNGPDM_01572 1.3e-33 ywzB S Protein of unknown function (DUF1146)
JNHNGPDM_01573 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JNHNGPDM_01574 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JNHNGPDM_01575 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JNHNGPDM_01576 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JNHNGPDM_01577 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JNHNGPDM_01578 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JNHNGPDM_01579 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JNHNGPDM_01580 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
JNHNGPDM_01581 5e-232 pyrP F Permease
JNHNGPDM_01582 6.3e-129 yibF S overlaps another CDS with the same product name
JNHNGPDM_01583 9.9e-192 yibE S overlaps another CDS with the same product name
JNHNGPDM_01584 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JNHNGPDM_01585 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JNHNGPDM_01586 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JNHNGPDM_01587 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JNHNGPDM_01588 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JNHNGPDM_01589 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JNHNGPDM_01590 6e-108 tdk 2.7.1.21 F thymidine kinase
JNHNGPDM_01591 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
JNHNGPDM_01592 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
JNHNGPDM_01593 2.7e-223 arcD U Amino acid permease
JNHNGPDM_01594 2e-261 E Arginine ornithine antiporter
JNHNGPDM_01595 4.7e-79 argR K Regulates arginine biosynthesis genes
JNHNGPDM_01596 4.1e-239 arcA 3.5.3.6 E Arginine
JNHNGPDM_01597 3.9e-187 ampC V Beta-lactamase
JNHNGPDM_01598 1.9e-32
JNHNGPDM_01606 3.9e-27 mleP3 S Membrane transport protein
JNHNGPDM_01607 7.3e-121 T Transcriptional regulatory protein, C terminal
JNHNGPDM_01608 9.9e-239 T GHKL domain
JNHNGPDM_01609 4.7e-109 S Peptidase propeptide and YPEB domain
JNHNGPDM_01610 1.7e-76 P FAD-binding domain
JNHNGPDM_01611 4.3e-55 yphJ 4.1.1.44 S decarboxylase
JNHNGPDM_01612 5.3e-83 K Bacterial regulatory proteins, tetR family
JNHNGPDM_01613 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JNHNGPDM_01614 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
JNHNGPDM_01615 9.9e-143 S Oxidoreductase, aldo keto reductase family protein
JNHNGPDM_01616 2.6e-12 S Oxidoreductase, aldo keto reductase family protein
JNHNGPDM_01617 2.7e-85 C Flavodoxin
JNHNGPDM_01618 1.2e-123 K Transcriptional regulator
JNHNGPDM_01619 1.7e-28 K Transcriptional regulator
JNHNGPDM_01620 6.3e-88 lacA S transferase hexapeptide repeat
JNHNGPDM_01621 9.4e-32 S thiolester hydrolase activity
JNHNGPDM_01622 2e-152 S Alpha beta hydrolase
JNHNGPDM_01623 2.3e-93 padC Q Phenolic acid decarboxylase
JNHNGPDM_01624 9.5e-92 padR K Virulence activator alpha C-term
JNHNGPDM_01625 5.2e-65 GM NAD(P)H-binding
JNHNGPDM_01626 2.3e-155 ypuA S Protein of unknown function (DUF1002)
JNHNGPDM_01627 1.5e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
JNHNGPDM_01628 2.3e-57 K Transcriptional regulator
JNHNGPDM_01629 4.3e-40 K Transcriptional regulator
JNHNGPDM_01630 2.9e-162 akr5f 1.1.1.346 S reductase
JNHNGPDM_01631 1.4e-102 K Transcriptional regulator C-terminal region
JNHNGPDM_01632 2.1e-74 S membrane
JNHNGPDM_01633 6.1e-88 S membrane
JNHNGPDM_01634 1.2e-112 GM NAD(P)H-binding
JNHNGPDM_01635 1.1e-64 yneR
JNHNGPDM_01636 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
JNHNGPDM_01638 1.3e-66 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JNHNGPDM_01639 1.5e-64 doc
JNHNGPDM_01640 5.5e-29 S Protein of unknown function (DUF4065)
JNHNGPDM_01642 1.7e-131 1.6.5.2 GM NAD(P)H-binding
JNHNGPDM_01644 2.2e-20 QT PucR C-terminal helix-turn-helix domain
JNHNGPDM_01645 1.4e-96
JNHNGPDM_01646 3.7e-39 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
JNHNGPDM_01647 6.3e-25
JNHNGPDM_01648 4.8e-81 prrC S Protein conserved in bacteria
JNHNGPDM_01653 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JNHNGPDM_01654 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
JNHNGPDM_01655 7.7e-133 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JNHNGPDM_01656 6.8e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
JNHNGPDM_01657 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JNHNGPDM_01658 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JNHNGPDM_01659 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JNHNGPDM_01660 4.2e-130 IQ reductase
JNHNGPDM_01661 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JNHNGPDM_01662 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JNHNGPDM_01663 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JNHNGPDM_01664 4.2e-77 marR K Transcriptional regulator, MarR family
JNHNGPDM_01665 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JNHNGPDM_01667 9.6e-200 xerS L Belongs to the 'phage' integrase family
JNHNGPDM_01668 2.6e-242 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
JNHNGPDM_01669 1.4e-158 rssA S Phospholipase, patatin family
JNHNGPDM_01670 2.5e-118 L Integrase
JNHNGPDM_01671 1.2e-152 EG EamA-like transporter family
JNHNGPDM_01672 1.4e-20
JNHNGPDM_01673 0.0 L Helicase C-terminal domain protein
JNHNGPDM_01674 9.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
JNHNGPDM_01675 1e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JNHNGPDM_01676 5.1e-187 yegS 2.7.1.107 G Lipid kinase
JNHNGPDM_01677 5.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JNHNGPDM_01678 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JNHNGPDM_01679 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JNHNGPDM_01680 2.1e-202 camS S sex pheromone
JNHNGPDM_01681 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JNHNGPDM_01682 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JNHNGPDM_01683 5.7e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JNHNGPDM_01684 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JNHNGPDM_01685 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
JNHNGPDM_01686 6.1e-140 IQ reductase
JNHNGPDM_01687 1.3e-96 yslB S Protein of unknown function (DUF2507)
JNHNGPDM_01688 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JNHNGPDM_01689 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JNHNGPDM_01690 4.4e-94 S Phosphoesterase
JNHNGPDM_01691 3.6e-76 ykuL S (CBS) domain
JNHNGPDM_01692 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
JNHNGPDM_01693 3.4e-147 ykuT M mechanosensitive ion channel
JNHNGPDM_01694 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JNHNGPDM_01695 3.5e-26
JNHNGPDM_01696 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JNHNGPDM_01697 1.9e-181 ccpA K catabolite control protein A
JNHNGPDM_01698 1.9e-134
JNHNGPDM_01699 3.5e-132 yebC K Transcriptional regulatory protein
JNHNGPDM_01700 2.6e-180 comGA NU Type II IV secretion system protein
JNHNGPDM_01701 9.5e-181 comGB NU type II secretion system
JNHNGPDM_01702 7.1e-47 comGC U competence protein ComGC
JNHNGPDM_01703 8.3e-78 NU general secretion pathway protein
JNHNGPDM_01704 2.7e-40
JNHNGPDM_01705 6.3e-70
JNHNGPDM_01707 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
JNHNGPDM_01708 4.6e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JNHNGPDM_01709 2.2e-113 S Calcineurin-like phosphoesterase
JNHNGPDM_01710 1.3e-93 yutD S Protein of unknown function (DUF1027)
JNHNGPDM_01711 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JNHNGPDM_01712 7e-105 S Protein of unknown function (DUF1461)
JNHNGPDM_01713 5.5e-110 dedA S SNARE-like domain protein
JNHNGPDM_01716 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
JNHNGPDM_01717 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JNHNGPDM_01718 8.1e-154 KT YcbB domain
JNHNGPDM_01719 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
JNHNGPDM_01720 2.9e-196 xylR GK ROK family
JNHNGPDM_01721 1.3e-28
JNHNGPDM_01722 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
JNHNGPDM_01723 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
JNHNGPDM_01724 2.6e-155 glcU U sugar transport
JNHNGPDM_01725 6.8e-273 yclK 2.7.13.3 T Histidine kinase
JNHNGPDM_01726 5.7e-132 K response regulator
JNHNGPDM_01728 2.8e-79 lytE M Lysin motif
JNHNGPDM_01729 2e-149 XK27_02985 S Cof-like hydrolase
JNHNGPDM_01730 2.3e-81 K Transcriptional regulator
JNHNGPDM_01731 0.0 oatA I Acyltransferase
JNHNGPDM_01732 8.7e-53
JNHNGPDM_01733 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JNHNGPDM_01734 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JNHNGPDM_01735 2e-126 ybbR S YbbR-like protein
JNHNGPDM_01736 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JNHNGPDM_01737 4.8e-249 fucP G Major Facilitator Superfamily
JNHNGPDM_01738 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JNHNGPDM_01739 2.9e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JNHNGPDM_01740 1.6e-168 murB 1.3.1.98 M Cell wall formation
JNHNGPDM_01741 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
JNHNGPDM_01742 4.4e-76 S PAS domain
JNHNGPDM_01743 2.6e-86 K Acetyltransferase (GNAT) domain
JNHNGPDM_01744 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
JNHNGPDM_01745 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JNHNGPDM_01746 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JNHNGPDM_01747 6.3e-105 yxjI
JNHNGPDM_01748 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JNHNGPDM_01749 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JNHNGPDM_01750 3.4e-146 est 3.1.1.1 S Serine aminopeptidase, S33
JNHNGPDM_01751 1.8e-34 secG U Preprotein translocase
JNHNGPDM_01752 2.6e-291 clcA P chloride
JNHNGPDM_01753 7.1e-248 yifK E Amino acid permease
JNHNGPDM_01754 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JNHNGPDM_01755 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JNHNGPDM_01756 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JNHNGPDM_01757 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JNHNGPDM_01759 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JNHNGPDM_01760 8.8e-15
JNHNGPDM_01762 4e-170 whiA K May be required for sporulation
JNHNGPDM_01763 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JNHNGPDM_01764 1.1e-161 rapZ S Displays ATPase and GTPase activities
JNHNGPDM_01765 5.4e-245 steT E amino acid
JNHNGPDM_01766 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JNHNGPDM_01767 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JNHNGPDM_01768 1.5e-13
JNHNGPDM_01769 2.3e-116 yfbR S HD containing hydrolase-like enzyme
JNHNGPDM_01770 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
JNHNGPDM_01771 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
JNHNGPDM_01772 1.3e-157 aatB ET PFAM extracellular solute-binding protein, family 3
JNHNGPDM_01773 2.5e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JNHNGPDM_01774 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JNHNGPDM_01775 3.5e-163 lutA C Cysteine-rich domain
JNHNGPDM_01776 7.5e-288 lutB C 4Fe-4S dicluster domain
JNHNGPDM_01777 3.9e-136 yrjD S LUD domain
JNHNGPDM_01778 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JNHNGPDM_01779 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JNHNGPDM_01780 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JNHNGPDM_01781 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JNHNGPDM_01782 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
JNHNGPDM_01783 3.1e-32 KT PspC domain protein
JNHNGPDM_01784 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JNHNGPDM_01785 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JNHNGPDM_01786 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JNHNGPDM_01787 1.3e-114 comFC S Competence protein
JNHNGPDM_01788 1.4e-256 comFA L Helicase C-terminal domain protein
JNHNGPDM_01789 2.9e-111 yvyE 3.4.13.9 S YigZ family
JNHNGPDM_01790 4e-235 EGP Major facilitator Superfamily
JNHNGPDM_01791 7.4e-68 rmaI K Transcriptional regulator
JNHNGPDM_01792 9.2e-40
JNHNGPDM_01793 0.0 ydaO E amino acid
JNHNGPDM_01794 7.3e-305 ybeC E amino acid
JNHNGPDM_01795 1.1e-81 S YbaK proline--tRNA ligase associated domain protein
JNHNGPDM_01796 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JNHNGPDM_01797 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JNHNGPDM_01799 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JNHNGPDM_01800 3.9e-133 K Transcriptional regulatory protein, C-terminal domain protein
JNHNGPDM_01801 7.3e-158 pstS P Phosphate
JNHNGPDM_01802 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
JNHNGPDM_01803 5.5e-153 pstA P Phosphate transport system permease protein PstA
JNHNGPDM_01804 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JNHNGPDM_01805 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
JNHNGPDM_01806 4.8e-39 L Integrase core domain
JNHNGPDM_01811 7.4e-40 L Integrase core domain
JNHNGPDM_01812 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
JNHNGPDM_01813 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JNHNGPDM_01814 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JNHNGPDM_01815 2.2e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNHNGPDM_01816 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNHNGPDM_01817 8.8e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNHNGPDM_01818 1.1e-62 rplQ J Ribosomal protein L17
JNHNGPDM_01819 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JNHNGPDM_01820 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JNHNGPDM_01821 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JNHNGPDM_01822 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JNHNGPDM_01823 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JNHNGPDM_01824 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JNHNGPDM_01825 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JNHNGPDM_01826 8.9e-64 rplO J Binds to the 23S rRNA
JNHNGPDM_01827 2.9e-24 rpmD J Ribosomal protein L30
JNHNGPDM_01828 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JNHNGPDM_01829 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JNHNGPDM_01830 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JNHNGPDM_01831 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JNHNGPDM_01832 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JNHNGPDM_01833 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JNHNGPDM_01834 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JNHNGPDM_01835 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JNHNGPDM_01836 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
JNHNGPDM_01837 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JNHNGPDM_01838 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JNHNGPDM_01839 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JNHNGPDM_01840 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JNHNGPDM_01841 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JNHNGPDM_01842 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JNHNGPDM_01843 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
JNHNGPDM_01844 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JNHNGPDM_01845 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JNHNGPDM_01846 3.3e-161 EG EamA-like transporter family
JNHNGPDM_01847 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
JNHNGPDM_01848 2.5e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JNHNGPDM_01849 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JNHNGPDM_01850 0.0 copA 3.6.3.54 P P-type ATPase
JNHNGPDM_01851 4.5e-85
JNHNGPDM_01853 5.2e-56
JNHNGPDM_01855 1e-73 yjcE P Sodium proton antiporter
JNHNGPDM_01856 1.9e-159 yjcE P Sodium proton antiporter
JNHNGPDM_01858 5.9e-91
JNHNGPDM_01859 0.0 M domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)