ORF_ID e_value Gene_name EC_number CAZy COGs Description
GPDFAPLJ_00001 7.4e-40 L Integrase core domain
GPDFAPLJ_00002 4.1e-228 L transposase, IS605 OrfB family
GPDFAPLJ_00003 2.1e-60 L PFAM transposase IS200-family protein
GPDFAPLJ_00005 0.0 L PLD-like domain
GPDFAPLJ_00006 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GPDFAPLJ_00007 4.3e-61 3.1.21.3 V type I restriction modification DNA specificity domain
GPDFAPLJ_00008 2.1e-177 xerC L Belongs to the 'phage' integrase family
GPDFAPLJ_00009 1.4e-39 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction
GPDFAPLJ_00010 1.1e-26 3.1.21.3 V Type I restriction modification DNA specificity domain
GPDFAPLJ_00011 6.1e-301 2.1.1.72 V type I restriction-modification system
GPDFAPLJ_00012 4.1e-57 yhaI S Protein of unknown function (DUF805)
GPDFAPLJ_00013 2.2e-44
GPDFAPLJ_00014 2.4e-22
GPDFAPLJ_00015 5.4e-47
GPDFAPLJ_00016 2.9e-96 K Acetyltransferase (GNAT) domain
GPDFAPLJ_00017 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GPDFAPLJ_00018 3e-39 gntT EG Gluconate
GPDFAPLJ_00019 4.9e-160 gntT EG Gluconate
GPDFAPLJ_00020 9.9e-183 K Transcriptional regulator, LacI family
GPDFAPLJ_00021 7e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GPDFAPLJ_00022 3.2e-95
GPDFAPLJ_00023 2.1e-25
GPDFAPLJ_00024 1.3e-61 asp S Asp23 family, cell envelope-related function
GPDFAPLJ_00025 3.5e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
GPDFAPLJ_00027 2.7e-49
GPDFAPLJ_00028 1.6e-67 yqkB S Belongs to the HesB IscA family
GPDFAPLJ_00029 5.9e-114 L PFAM Integrase catalytic region
GPDFAPLJ_00030 2.1e-60 L PFAM transposase IS200-family protein
GPDFAPLJ_00031 4.1e-228 L transposase, IS605 OrfB family
GPDFAPLJ_00032 9e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GPDFAPLJ_00033 5e-185 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPDFAPLJ_00034 7.3e-96 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
GPDFAPLJ_00035 1.9e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GPDFAPLJ_00036 5.7e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GPDFAPLJ_00037 4.7e-102 T Ion transport 2 domain protein
GPDFAPLJ_00038 0.0 S Bacterial membrane protein YfhO
GPDFAPLJ_00039 5e-202 G Transporter, major facilitator family protein
GPDFAPLJ_00040 2.4e-109 yvrI K sigma factor activity
GPDFAPLJ_00041 3.5e-64 ydiI Q Thioesterase superfamily
GPDFAPLJ_00042 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPDFAPLJ_00043 4.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GPDFAPLJ_00044 5.5e-19
GPDFAPLJ_00045 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
GPDFAPLJ_00046 4.2e-32 feoA P FeoA domain
GPDFAPLJ_00047 6.5e-145 sufC O FeS assembly ATPase SufC
GPDFAPLJ_00048 7.3e-239 sufD O FeS assembly protein SufD
GPDFAPLJ_00049 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPDFAPLJ_00050 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
GPDFAPLJ_00051 1.6e-271 sufB O assembly protein SufB
GPDFAPLJ_00052 2.8e-57 yitW S Iron-sulfur cluster assembly protein
GPDFAPLJ_00053 6.1e-160 hipB K Helix-turn-helix
GPDFAPLJ_00054 8.3e-114 nreC K PFAM regulatory protein LuxR
GPDFAPLJ_00055 9.2e-39 S Cytochrome B5
GPDFAPLJ_00056 6.4e-156 yitU 3.1.3.104 S hydrolase
GPDFAPLJ_00057 2.5e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GPDFAPLJ_00058 4e-148 f42a O Band 7 protein
GPDFAPLJ_00059 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
GPDFAPLJ_00060 2.4e-130 lytT K response regulator receiver
GPDFAPLJ_00061 1.9e-66 lrgA S LrgA family
GPDFAPLJ_00062 2.6e-124 lrgB M LrgB-like family
GPDFAPLJ_00063 9.3e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPDFAPLJ_00064 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
GPDFAPLJ_00065 4.2e-189 galR K Periplasmic binding protein-like domain
GPDFAPLJ_00066 0.0 rafA 3.2.1.22 G alpha-galactosidase
GPDFAPLJ_00067 3.8e-87 S Protein of unknown function (DUF1440)
GPDFAPLJ_00068 1.4e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GPDFAPLJ_00069 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GPDFAPLJ_00070 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GPDFAPLJ_00071 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GPDFAPLJ_00072 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GPDFAPLJ_00073 2.9e-85 ypmB S Protein conserved in bacteria
GPDFAPLJ_00074 3e-125 dnaD L DnaD domain protein
GPDFAPLJ_00075 2e-161 EG EamA-like transporter family
GPDFAPLJ_00076 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GPDFAPLJ_00077 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPDFAPLJ_00078 1.6e-105 ypsA S Belongs to the UPF0398 family
GPDFAPLJ_00079 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GPDFAPLJ_00080 2.1e-60 L PFAM transposase IS200-family protein
GPDFAPLJ_00081 4.1e-228 L transposase, IS605 OrfB family
GPDFAPLJ_00082 1.9e-34 T Toxin-antitoxin system, toxin component, MazF family
GPDFAPLJ_00083 8.9e-37
GPDFAPLJ_00084 6.7e-07 D nuclear chromosome segregation
GPDFAPLJ_00085 0.0 snf 2.7.11.1 KL domain protein
GPDFAPLJ_00086 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
GPDFAPLJ_00087 1e-170 M Glycosyl hydrolases family 25
GPDFAPLJ_00088 6.4e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GPDFAPLJ_00089 0.0 sbcC L Putative exonuclease SbcCD, C subunit
GPDFAPLJ_00090 5.9e-114 L PFAM Integrase catalytic region
GPDFAPLJ_00091 7e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
GPDFAPLJ_00092 1.2e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
GPDFAPLJ_00093 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPDFAPLJ_00094 1.8e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPDFAPLJ_00095 7.3e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPDFAPLJ_00096 1.2e-135 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPDFAPLJ_00097 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
GPDFAPLJ_00098 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
GPDFAPLJ_00099 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPDFAPLJ_00100 0.0 uup S ABC transporter, ATP-binding protein
GPDFAPLJ_00101 5.9e-114 L PFAM Integrase catalytic region
GPDFAPLJ_00102 2.8e-35
GPDFAPLJ_00103 9.3e-62 K DNA-templated transcription, initiation
GPDFAPLJ_00104 3e-41 K Transcriptional regulator, HxlR family
GPDFAPLJ_00105 2.4e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GPDFAPLJ_00106 3.8e-146 epsB M biosynthesis protein
GPDFAPLJ_00107 3.9e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
GPDFAPLJ_00108 5.7e-115 rfbP M Bacterial sugar transferase
GPDFAPLJ_00109 3.7e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPDFAPLJ_00110 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GPDFAPLJ_00111 2e-194 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPDFAPLJ_00112 1.8e-184 M family 8
GPDFAPLJ_00113 5.4e-181 GT2 M Glycosyltransferase like family 2
GPDFAPLJ_00114 7.5e-183 M Glycosyl transferase, family 2
GPDFAPLJ_00115 7.8e-233 S Psort location CytoplasmicMembrane, score 9.99
GPDFAPLJ_00116 3e-238 S polysaccharide biosynthetic process
GPDFAPLJ_00117 1.3e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
GPDFAPLJ_00118 6.6e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPDFAPLJ_00119 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPDFAPLJ_00120 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
GPDFAPLJ_00121 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPDFAPLJ_00122 7.4e-141 ymfM S Helix-turn-helix domain
GPDFAPLJ_00123 6e-249 ymfH S Peptidase M16
GPDFAPLJ_00124 1.6e-230 ymfF S Peptidase M16 inactive domain protein
GPDFAPLJ_00125 2.6e-160 aatB ET ABC transporter substrate-binding protein
GPDFAPLJ_00126 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPDFAPLJ_00127 3.2e-102 glnP P ABC transporter permease
GPDFAPLJ_00128 1.2e-91 mreD M rod shape-determining protein MreD
GPDFAPLJ_00129 8.5e-151 mreC M Involved in formation and maintenance of cell shape
GPDFAPLJ_00130 1.7e-179 mreB D cell shape determining protein MreB
GPDFAPLJ_00131 6.8e-121 radC L DNA repair protein
GPDFAPLJ_00132 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GPDFAPLJ_00133 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
GPDFAPLJ_00134 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPDFAPLJ_00135 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GPDFAPLJ_00136 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
GPDFAPLJ_00137 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
GPDFAPLJ_00138 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GPDFAPLJ_00139 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPDFAPLJ_00140 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
GPDFAPLJ_00141 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GPDFAPLJ_00142 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPDFAPLJ_00143 1.3e-262 L Transposase
GPDFAPLJ_00144 1.1e-235 pbuG S permease
GPDFAPLJ_00145 4.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GPDFAPLJ_00146 8.2e-93 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GPDFAPLJ_00147 1.1e-206 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GPDFAPLJ_00148 2.5e-135 S Belongs to the UPF0246 family
GPDFAPLJ_00149 2.5e-138 S Membrane
GPDFAPLJ_00150 8.1e-75 4.4.1.5 E Glyoxalase
GPDFAPLJ_00151 1.5e-21
GPDFAPLJ_00152 7.1e-86 yueI S Protein of unknown function (DUF1694)
GPDFAPLJ_00153 1.7e-235 rarA L recombination factor protein RarA
GPDFAPLJ_00154 1.7e-45
GPDFAPLJ_00155 4.3e-83 usp6 T universal stress protein
GPDFAPLJ_00156 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
GPDFAPLJ_00157 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GPDFAPLJ_00158 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
GPDFAPLJ_00159 2e-92 folT S ECF transporter, substrate-specific component
GPDFAPLJ_00160 0.0 pepN 3.4.11.2 E aminopeptidase
GPDFAPLJ_00161 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
GPDFAPLJ_00162 9.8e-255 pepC 3.4.22.40 E aminopeptidase
GPDFAPLJ_00163 6.5e-210 EGP Major facilitator Superfamily
GPDFAPLJ_00164 2.4e-229
GPDFAPLJ_00165 7.8e-79 K Transcriptional regulator, HxlR family
GPDFAPLJ_00166 3.7e-108 XK27_02070 S Nitroreductase family
GPDFAPLJ_00167 2.5e-52 hxlR K Transcriptional regulator, HxlR family
GPDFAPLJ_00168 3e-119 GM NmrA-like family
GPDFAPLJ_00169 1.7e-70 elaA S Gnat family
GPDFAPLJ_00170 1.8e-39 S Cytochrome B5
GPDFAPLJ_00171 5.4e-09 S Cytochrome B5
GPDFAPLJ_00172 7.8e-41 S Cytochrome B5
GPDFAPLJ_00173 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
GPDFAPLJ_00175 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPDFAPLJ_00176 1.1e-240 E amino acid
GPDFAPLJ_00177 2.8e-215 npp S type I phosphodiesterase nucleotide pyrophosphatase
GPDFAPLJ_00178 3.1e-226 yxiO S Vacuole effluxer Atg22 like
GPDFAPLJ_00180 4.4e-100 L Helix-turn-helix domain
GPDFAPLJ_00181 4.5e-160 L hmm pf00665
GPDFAPLJ_00182 3.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPDFAPLJ_00183 1e-265 yfnA E amino acid
GPDFAPLJ_00184 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPDFAPLJ_00185 5.8e-40 1.3.5.4 S FMN binding
GPDFAPLJ_00186 3.7e-221 norA EGP Major facilitator Superfamily
GPDFAPLJ_00187 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPDFAPLJ_00188 4.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
GPDFAPLJ_00189 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPDFAPLJ_00190 3.1e-103 metI P ABC transporter permease
GPDFAPLJ_00191 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GPDFAPLJ_00192 1.3e-251 clcA P chloride
GPDFAPLJ_00193 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GPDFAPLJ_00194 4.5e-104 proW P ABC transporter, permease protein
GPDFAPLJ_00195 1e-139 proV E ABC transporter, ATP-binding protein
GPDFAPLJ_00196 6.3e-109 proWZ P ABC transporter permease
GPDFAPLJ_00197 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
GPDFAPLJ_00198 9e-75 K Transcriptional regulator
GPDFAPLJ_00199 4.8e-154 1.6.5.2 GM NAD(P)H-binding
GPDFAPLJ_00201 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
GPDFAPLJ_00202 0.0 cadA P P-type ATPase
GPDFAPLJ_00203 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GPDFAPLJ_00204 2.1e-126
GPDFAPLJ_00205 3.3e-55 S Sugar efflux transporter for intercellular exchange
GPDFAPLJ_00206 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GPDFAPLJ_00208 0.0 L Helicase C-terminal domain protein
GPDFAPLJ_00209 6.9e-76 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
GPDFAPLJ_00210 2.2e-176 S Aldo keto reductase
GPDFAPLJ_00211 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPDFAPLJ_00212 3.2e-125 S Putative adhesin
GPDFAPLJ_00213 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
GPDFAPLJ_00214 4e-56 K transcriptional regulator PadR family
GPDFAPLJ_00215 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GPDFAPLJ_00217 1.2e-230 L Integrase core domain
GPDFAPLJ_00218 5.1e-139 L Bacterial dnaA protein
GPDFAPLJ_00219 5.7e-38
GPDFAPLJ_00220 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GPDFAPLJ_00221 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPDFAPLJ_00222 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPDFAPLJ_00223 9.6e-247 M Glycosyl transferase family group 2
GPDFAPLJ_00225 1.3e-226 aadAT EK Aminotransferase, class I
GPDFAPLJ_00226 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GPDFAPLJ_00227 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPDFAPLJ_00228 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
GPDFAPLJ_00229 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GPDFAPLJ_00230 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPDFAPLJ_00231 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPDFAPLJ_00232 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPDFAPLJ_00233 1.9e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPDFAPLJ_00234 1.7e-207 yacL S domain protein
GPDFAPLJ_00235 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPDFAPLJ_00236 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GPDFAPLJ_00237 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
GPDFAPLJ_00238 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPDFAPLJ_00239 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
GPDFAPLJ_00240 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GPDFAPLJ_00241 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPDFAPLJ_00242 2.4e-119 tcyB E ABC transporter
GPDFAPLJ_00243 1.2e-213 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPDFAPLJ_00244 3.1e-169 I alpha/beta hydrolase fold
GPDFAPLJ_00245 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPDFAPLJ_00246 0.0 S Bacterial membrane protein, YfhO
GPDFAPLJ_00247 2.7e-182 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
GPDFAPLJ_00248 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
GPDFAPLJ_00250 1.7e-81 ydcK S Belongs to the SprT family
GPDFAPLJ_00251 0.0 yhgF K Tex-like protein N-terminal domain protein
GPDFAPLJ_00252 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GPDFAPLJ_00253 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPDFAPLJ_00254 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
GPDFAPLJ_00255 2.4e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GPDFAPLJ_00256 1.8e-298 aspT P Predicted Permease Membrane Region
GPDFAPLJ_00257 2.8e-252 EGP Major facilitator Superfamily
GPDFAPLJ_00258 5.5e-110
GPDFAPLJ_00261 1.4e-158 yjjH S Calcineurin-like phosphoesterase
GPDFAPLJ_00262 5e-263 dtpT U amino acid peptide transporter
GPDFAPLJ_00263 3.7e-19
GPDFAPLJ_00265 3.7e-91 yqiG C Oxidoreductase
GPDFAPLJ_00266 3.7e-84 yqiG C Oxidoreductase
GPDFAPLJ_00267 8.5e-54 S macrophage migration inhibitory factor
GPDFAPLJ_00268 2.4e-65 K HxlR-like helix-turn-helix
GPDFAPLJ_00269 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPDFAPLJ_00271 1.9e-225 L Transposase IS66 family
GPDFAPLJ_00272 5.9e-114 L PFAM Integrase catalytic region
GPDFAPLJ_00285 1.5e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
GPDFAPLJ_00286 9.3e-130 IQ Dehydrogenase reductase
GPDFAPLJ_00287 9.2e-36
GPDFAPLJ_00288 4.8e-114 ywnB S NAD(P)H-binding
GPDFAPLJ_00289 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
GPDFAPLJ_00290 6.1e-255 nhaC C Na H antiporter NhaC
GPDFAPLJ_00291 3.4e-155 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPDFAPLJ_00293 2.1e-102 ydeN S Serine hydrolase
GPDFAPLJ_00294 4.5e-62 psiE S Phosphate-starvation-inducible E
GPDFAPLJ_00295 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPDFAPLJ_00297 0.0 M domain protein
GPDFAPLJ_00298 5.9e-91
GPDFAPLJ_00300 1.9e-159 yjcE P Sodium proton antiporter
GPDFAPLJ_00301 1e-73 yjcE P Sodium proton antiporter
GPDFAPLJ_00303 5.2e-56
GPDFAPLJ_00305 4.5e-85
GPDFAPLJ_00306 0.0 copA 3.6.3.54 P P-type ATPase
GPDFAPLJ_00307 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GPDFAPLJ_00308 2.5e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GPDFAPLJ_00309 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GPDFAPLJ_00310 3.3e-161 EG EamA-like transporter family
GPDFAPLJ_00311 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
GPDFAPLJ_00312 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPDFAPLJ_00313 8.1e-154 KT YcbB domain
GPDFAPLJ_00314 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
GPDFAPLJ_00315 2.9e-196 xylR GK ROK family
GPDFAPLJ_00316 1.3e-28
GPDFAPLJ_00317 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
GPDFAPLJ_00318 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
GPDFAPLJ_00319 2.6e-155 glcU U sugar transport
GPDFAPLJ_00320 6.8e-273 yclK 2.7.13.3 T Histidine kinase
GPDFAPLJ_00321 5.7e-132 K response regulator
GPDFAPLJ_00323 2.8e-79 lytE M Lysin motif
GPDFAPLJ_00324 2e-149 XK27_02985 S Cof-like hydrolase
GPDFAPLJ_00325 2.3e-81 K Transcriptional regulator
GPDFAPLJ_00326 0.0 oatA I Acyltransferase
GPDFAPLJ_00327 8.7e-53
GPDFAPLJ_00328 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GPDFAPLJ_00329 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPDFAPLJ_00330 2e-126 ybbR S YbbR-like protein
GPDFAPLJ_00331 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPDFAPLJ_00332 4.8e-249 fucP G Major Facilitator Superfamily
GPDFAPLJ_00333 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GPDFAPLJ_00334 2.9e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPDFAPLJ_00335 1.6e-168 murB 1.3.1.98 M Cell wall formation
GPDFAPLJ_00336 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
GPDFAPLJ_00337 4.4e-76 S PAS domain
GPDFAPLJ_00338 2.6e-86 K Acetyltransferase (GNAT) domain
GPDFAPLJ_00339 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
GPDFAPLJ_00340 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GPDFAPLJ_00341 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPDFAPLJ_00342 6.3e-105 yxjI
GPDFAPLJ_00343 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GPDFAPLJ_00344 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GPDFAPLJ_00345 3.4e-146 est 3.1.1.1 S Serine aminopeptidase, S33
GPDFAPLJ_00346 1.8e-34 secG U Preprotein translocase
GPDFAPLJ_00347 2.6e-291 clcA P chloride
GPDFAPLJ_00348 7.1e-248 yifK E Amino acid permease
GPDFAPLJ_00349 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GPDFAPLJ_00350 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPDFAPLJ_00351 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GPDFAPLJ_00352 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPDFAPLJ_00354 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPDFAPLJ_00355 8.8e-15
GPDFAPLJ_00357 4e-170 whiA K May be required for sporulation
GPDFAPLJ_00358 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GPDFAPLJ_00359 1.1e-161 rapZ S Displays ATPase and GTPase activities
GPDFAPLJ_00360 5.4e-245 steT E amino acid
GPDFAPLJ_00361 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GPDFAPLJ_00362 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GPDFAPLJ_00363 1.5e-13
GPDFAPLJ_00364 2.3e-116 yfbR S HD containing hydrolase-like enzyme
GPDFAPLJ_00365 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GPDFAPLJ_00366 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
GPDFAPLJ_00367 1.3e-157 aatB ET PFAM extracellular solute-binding protein, family 3
GPDFAPLJ_00368 2.5e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GPDFAPLJ_00369 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GPDFAPLJ_00370 3.5e-163 lutA C Cysteine-rich domain
GPDFAPLJ_00371 7.5e-288 lutB C 4Fe-4S dicluster domain
GPDFAPLJ_00372 3.9e-136 yrjD S LUD domain
GPDFAPLJ_00373 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPDFAPLJ_00374 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GPDFAPLJ_00375 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPDFAPLJ_00376 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GPDFAPLJ_00377 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
GPDFAPLJ_00378 3.1e-32 KT PspC domain protein
GPDFAPLJ_00379 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GPDFAPLJ_00380 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPDFAPLJ_00381 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPDFAPLJ_00382 1.2e-112 comFC S Competence protein
GPDFAPLJ_00383 1.4e-256 comFA L Helicase C-terminal domain protein
GPDFAPLJ_00384 2.9e-111 yvyE 3.4.13.9 S YigZ family
GPDFAPLJ_00385 4e-235 EGP Major facilitator Superfamily
GPDFAPLJ_00386 7.4e-68 rmaI K Transcriptional regulator
GPDFAPLJ_00387 9.2e-40
GPDFAPLJ_00388 0.0 ydaO E amino acid
GPDFAPLJ_00389 7.3e-305 ybeC E amino acid
GPDFAPLJ_00390 1.1e-81 S YbaK proline--tRNA ligase associated domain protein
GPDFAPLJ_00391 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GPDFAPLJ_00392 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPDFAPLJ_00394 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GPDFAPLJ_00395 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GPDFAPLJ_00396 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
GPDFAPLJ_00397 1.8e-161 S reductase
GPDFAPLJ_00399 3.6e-288 S amidohydrolase
GPDFAPLJ_00400 5.9e-152 K Aminotransferase class I and II
GPDFAPLJ_00401 7.3e-60 K Aminotransferase class I and II
GPDFAPLJ_00402 1.4e-119 azlC E azaleucine resistance protein AzlC
GPDFAPLJ_00403 7.1e-50 azlD E Branched-chain amino acid transport
GPDFAPLJ_00404 6.1e-117 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GPDFAPLJ_00406 2.7e-70 S GyrI-like small molecule binding domain
GPDFAPLJ_00407 6.4e-39 S GyrI-like small molecule binding domain
GPDFAPLJ_00408 5e-122 yhiD S MgtC family
GPDFAPLJ_00409 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPDFAPLJ_00410 5.9e-191 V Beta-lactamase
GPDFAPLJ_00412 4.4e-100 L Helix-turn-helix domain
GPDFAPLJ_00413 4.5e-160 L hmm pf00665
GPDFAPLJ_00414 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
GPDFAPLJ_00415 5e-141 sprD D Domain of Unknown Function (DUF1542)
GPDFAPLJ_00416 1.1e-126 L PFAM Integrase catalytic region
GPDFAPLJ_00417 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GPDFAPLJ_00418 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GPDFAPLJ_00419 2.6e-158 htpX O Belongs to the peptidase M48B family
GPDFAPLJ_00420 7e-93 lemA S LemA family
GPDFAPLJ_00421 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPDFAPLJ_00422 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
GPDFAPLJ_00423 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
GPDFAPLJ_00424 4e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPDFAPLJ_00425 4.4e-157 3.2.1.55 GH51 G Right handed beta helix region
GPDFAPLJ_00426 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GPDFAPLJ_00427 5.1e-125 srtA 3.4.22.70 M sortase family
GPDFAPLJ_00428 1.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
GPDFAPLJ_00429 1.8e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPDFAPLJ_00430 4.6e-41 rpmE2 J Ribosomal protein L31
GPDFAPLJ_00431 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPDFAPLJ_00432 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GPDFAPLJ_00433 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GPDFAPLJ_00434 3e-66 ywiB S Domain of unknown function (DUF1934)
GPDFAPLJ_00435 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
GPDFAPLJ_00436 5e-270 ywfO S HD domain protein
GPDFAPLJ_00437 2.5e-147 yxeH S hydrolase
GPDFAPLJ_00438 2.1e-49
GPDFAPLJ_00439 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPDFAPLJ_00440 3.4e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPDFAPLJ_00441 2.6e-149 purR 2.4.2.7 F pur operon repressor
GPDFAPLJ_00442 1.4e-118 znuB U ABC 3 transport family
GPDFAPLJ_00443 2.2e-122 fhuC P ABC transporter
GPDFAPLJ_00444 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
GPDFAPLJ_00445 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPDFAPLJ_00446 6.8e-37 veg S Biofilm formation stimulator VEG
GPDFAPLJ_00447 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GPDFAPLJ_00448 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPDFAPLJ_00449 1.9e-155 tatD L hydrolase, TatD family
GPDFAPLJ_00450 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPDFAPLJ_00451 3.6e-162 yunF F Protein of unknown function DUF72
GPDFAPLJ_00453 1e-130 cobB K SIR2 family
GPDFAPLJ_00454 1.6e-177
GPDFAPLJ_00455 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GPDFAPLJ_00456 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GPDFAPLJ_00457 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPDFAPLJ_00458 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
GPDFAPLJ_00459 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
GPDFAPLJ_00460 0.0 helD 3.6.4.12 L DNA helicase
GPDFAPLJ_00461 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GPDFAPLJ_00463 3.8e-60 S Uncharacterised protein family (UPF0236)
GPDFAPLJ_00464 4.8e-39 L Integrase core domain
GPDFAPLJ_00467 1.3e-66 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GPDFAPLJ_00468 1.4e-72
GPDFAPLJ_00469 3.5e-24
GPDFAPLJ_00470 4.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPDFAPLJ_00471 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
GPDFAPLJ_00472 7.9e-35 copZ C Heavy-metal-associated domain
GPDFAPLJ_00473 6.7e-93 dps P Belongs to the Dps family
GPDFAPLJ_00474 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
GPDFAPLJ_00475 3.9e-133 K Transcriptional regulatory protein, C-terminal domain protein
GPDFAPLJ_00476 7.3e-158 pstS P Phosphate
GPDFAPLJ_00477 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
GPDFAPLJ_00478 5.5e-153 pstA P Phosphate transport system permease protein PstA
GPDFAPLJ_00479 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPDFAPLJ_00480 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
GPDFAPLJ_00481 3.9e-27 mleP3 S Membrane transport protein
GPDFAPLJ_00482 7.3e-121 T Transcriptional regulatory protein, C terminal
GPDFAPLJ_00483 9.9e-239 T GHKL domain
GPDFAPLJ_00484 4.7e-109 S Peptidase propeptide and YPEB domain
GPDFAPLJ_00485 1.7e-76 P FAD-binding domain
GPDFAPLJ_00486 4.3e-55 yphJ 4.1.1.44 S decarboxylase
GPDFAPLJ_00487 5.3e-83 K Bacterial regulatory proteins, tetR family
GPDFAPLJ_00488 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPDFAPLJ_00489 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GPDFAPLJ_00490 9.9e-143 S Oxidoreductase, aldo keto reductase family protein
GPDFAPLJ_00491 2.6e-12 S Oxidoreductase, aldo keto reductase family protein
GPDFAPLJ_00492 2.7e-85 C Flavodoxin
GPDFAPLJ_00493 1.2e-123 K Transcriptional regulator
GPDFAPLJ_00494 1.7e-28 K Transcriptional regulator
GPDFAPLJ_00495 6.3e-88 lacA S transferase hexapeptide repeat
GPDFAPLJ_00496 9.4e-32 S thiolester hydrolase activity
GPDFAPLJ_00497 2e-152 S Alpha beta hydrolase
GPDFAPLJ_00498 2.3e-93 padC Q Phenolic acid decarboxylase
GPDFAPLJ_00499 9.5e-92 padR K Virulence activator alpha C-term
GPDFAPLJ_00500 5.2e-65 GM NAD(P)H-binding
GPDFAPLJ_00501 2.3e-155 ypuA S Protein of unknown function (DUF1002)
GPDFAPLJ_00502 1.5e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
GPDFAPLJ_00503 2.3e-57 K Transcriptional regulator
GPDFAPLJ_00504 4.3e-40 K Transcriptional regulator
GPDFAPLJ_00505 2.9e-162 akr5f 1.1.1.346 S reductase
GPDFAPLJ_00506 1.4e-102 K Transcriptional regulator C-terminal region
GPDFAPLJ_00507 2.1e-74 S membrane
GPDFAPLJ_00508 6.1e-88 S membrane
GPDFAPLJ_00509 1.2e-112 GM NAD(P)H-binding
GPDFAPLJ_00510 1.1e-64 yneR
GPDFAPLJ_00511 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
GPDFAPLJ_00512 4.8e-81 prrC S Protein conserved in bacteria
GPDFAPLJ_00513 6.3e-25
GPDFAPLJ_00514 3.7e-39 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GPDFAPLJ_00515 1.4e-96
GPDFAPLJ_00516 2.2e-20 QT PucR C-terminal helix-turn-helix domain
GPDFAPLJ_00518 1.7e-131 1.6.5.2 GM NAD(P)H-binding
GPDFAPLJ_00520 5.5e-29 S Protein of unknown function (DUF4065)
GPDFAPLJ_00521 1.5e-64 doc
GPDFAPLJ_00524 1.4e-20
GPDFAPLJ_00525 0.0 L Helicase C-terminal domain protein
GPDFAPLJ_00526 9.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
GPDFAPLJ_00527 1e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPDFAPLJ_00528 5.1e-187 yegS 2.7.1.107 G Lipid kinase
GPDFAPLJ_00529 5.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPDFAPLJ_00530 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GPDFAPLJ_00531 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPDFAPLJ_00532 2.1e-202 camS S sex pheromone
GPDFAPLJ_00533 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPDFAPLJ_00534 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GPDFAPLJ_00535 5.7e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPDFAPLJ_00536 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GPDFAPLJ_00537 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
GPDFAPLJ_00538 6.1e-140 IQ reductase
GPDFAPLJ_00539 6.6e-262 S Putative peptidoglycan binding domain
GPDFAPLJ_00540 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
GPDFAPLJ_00541 2.2e-87
GPDFAPLJ_00542 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
GPDFAPLJ_00543 2.6e-214 yttB EGP Major facilitator Superfamily
GPDFAPLJ_00544 8.2e-103
GPDFAPLJ_00545 3e-24
GPDFAPLJ_00546 5.1e-173 scrR K Transcriptional regulator, LacI family
GPDFAPLJ_00547 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPDFAPLJ_00548 3.5e-49 czrA K Transcriptional regulator, ArsR family
GPDFAPLJ_00557 2.1e-55 S Protein of unknown function (DUF3290)
GPDFAPLJ_00558 6.9e-113 yviA S Protein of unknown function (DUF421)
GPDFAPLJ_00559 4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
GPDFAPLJ_00560 1.3e-20
GPDFAPLJ_00561 8.1e-90 ntd 2.4.2.6 F Nucleoside
GPDFAPLJ_00562 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
GPDFAPLJ_00563 1.6e-45 yrvD S Pfam:DUF1049
GPDFAPLJ_00565 1.1e-35 S Phage derived protein Gp49-like (DUF891)
GPDFAPLJ_00566 8.5e-20 K Helix-turn-helix XRE-family like proteins
GPDFAPLJ_00567 1.7e-78 I alpha/beta hydrolase fold
GPDFAPLJ_00568 1.1e-113 frnE Q DSBA-like thioredoxin domain
GPDFAPLJ_00569 2e-53
GPDFAPLJ_00570 9.3e-189 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPDFAPLJ_00572 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
GPDFAPLJ_00573 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
GPDFAPLJ_00574 1.8e-226 clcA_2 P Chloride transporter, ClC family
GPDFAPLJ_00575 4.4e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GPDFAPLJ_00576 4.7e-85 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPDFAPLJ_00577 8.3e-22 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPDFAPLJ_00578 6.7e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPDFAPLJ_00579 5.2e-50
GPDFAPLJ_00580 0.0 S SEC-C Motif Domain Protein
GPDFAPLJ_00581 5.5e-110 dedA S SNARE-like domain protein
GPDFAPLJ_00582 7e-105 S Protein of unknown function (DUF1461)
GPDFAPLJ_00583 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GPDFAPLJ_00584 1.3e-93 yutD S Protein of unknown function (DUF1027)
GPDFAPLJ_00585 2.2e-113 S Calcineurin-like phosphoesterase
GPDFAPLJ_00586 4.6e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPDFAPLJ_00587 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
GPDFAPLJ_00589 6.3e-70
GPDFAPLJ_00590 2.7e-40
GPDFAPLJ_00591 8.3e-78 NU general secretion pathway protein
GPDFAPLJ_00592 7.1e-47 comGC U competence protein ComGC
GPDFAPLJ_00593 9.5e-181 comGB NU type II secretion system
GPDFAPLJ_00594 2.6e-180 comGA NU Type II IV secretion system protein
GPDFAPLJ_00595 3.5e-132 yebC K Transcriptional regulatory protein
GPDFAPLJ_00596 1.9e-134
GPDFAPLJ_00597 1.9e-181 ccpA K catabolite control protein A
GPDFAPLJ_00598 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GPDFAPLJ_00599 3.5e-26
GPDFAPLJ_00600 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPDFAPLJ_00601 3.4e-147 ykuT M mechanosensitive ion channel
GPDFAPLJ_00602 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
GPDFAPLJ_00603 3.6e-76 ykuL S (CBS) domain
GPDFAPLJ_00604 4.4e-94 S Phosphoesterase
GPDFAPLJ_00605 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPDFAPLJ_00606 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPDFAPLJ_00607 1.3e-96 yslB S Protein of unknown function (DUF2507)
GPDFAPLJ_00608 5e-75 osmC O OsmC-like protein
GPDFAPLJ_00609 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPDFAPLJ_00610 1.8e-215 patA 2.6.1.1 E Aminotransferase
GPDFAPLJ_00611 7.8e-32
GPDFAPLJ_00612 0.0 clpL O associated with various cellular activities
GPDFAPLJ_00614 9.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
GPDFAPLJ_00615 6.1e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPDFAPLJ_00616 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GPDFAPLJ_00617 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GPDFAPLJ_00618 1.5e-172 malR K Transcriptional regulator, LacI family
GPDFAPLJ_00619 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
GPDFAPLJ_00620 1.1e-256 malT G Major Facilitator
GPDFAPLJ_00621 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GPDFAPLJ_00622 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
GPDFAPLJ_00623 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
GPDFAPLJ_00624 3.3e-118 K response regulator
GPDFAPLJ_00625 5.3e-226 sptS 2.7.13.3 T Histidine kinase
GPDFAPLJ_00626 2.5e-209 yfeO P Voltage gated chloride channel
GPDFAPLJ_00627 8.9e-256 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GPDFAPLJ_00628 6.6e-136 puuD S peptidase C26
GPDFAPLJ_00629 3.8e-167 yvgN C Aldo keto reductase
GPDFAPLJ_00630 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
GPDFAPLJ_00631 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
GPDFAPLJ_00632 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
GPDFAPLJ_00633 4.2e-261 nox C NADH oxidase
GPDFAPLJ_00634 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPDFAPLJ_00635 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPDFAPLJ_00636 3e-86
GPDFAPLJ_00637 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GPDFAPLJ_00639 1.1e-163 yueF S AI-2E family transporter
GPDFAPLJ_00640 6.9e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GPDFAPLJ_00641 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPDFAPLJ_00642 2.2e-34 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
GPDFAPLJ_00643 4.7e-217 M NlpC/P60 family
GPDFAPLJ_00644 1.2e-174 M NlpC/P60 family
GPDFAPLJ_00645 7e-55 M NlpC/P60 family
GPDFAPLJ_00646 0.0 S Peptidase, M23
GPDFAPLJ_00647 0.0 bamA GM domain, Protein
GPDFAPLJ_00648 7.9e-64 gntR1 K Transcriptional regulator, GntR family
GPDFAPLJ_00649 1e-156 V ABC transporter, ATP-binding protein
GPDFAPLJ_00650 6.7e-114
GPDFAPLJ_00651 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
GPDFAPLJ_00652 2.4e-99 S Pfam:DUF3816
GPDFAPLJ_00653 0.0 clpE O Belongs to the ClpA ClpB family
GPDFAPLJ_00654 2.9e-27
GPDFAPLJ_00655 2.7e-39 ptsH G phosphocarrier protein HPR
GPDFAPLJ_00656 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPDFAPLJ_00657 6.7e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GPDFAPLJ_00658 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
GPDFAPLJ_00659 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPDFAPLJ_00660 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
GPDFAPLJ_00663 2.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPDFAPLJ_00664 1.7e-183 S Phosphotransferase system, EIIC
GPDFAPLJ_00665 2.3e-162
GPDFAPLJ_00666 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
GPDFAPLJ_00667 2.8e-170 S AI-2E family transporter
GPDFAPLJ_00668 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
GPDFAPLJ_00669 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
GPDFAPLJ_00670 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
GPDFAPLJ_00671 4.8e-88 GM epimerase
GPDFAPLJ_00672 1.7e-154 ypdB V (ABC) transporter
GPDFAPLJ_00673 6.2e-241 yhdP S Transporter associated domain
GPDFAPLJ_00674 9.9e-85 nrdI F Belongs to the NrdI family
GPDFAPLJ_00675 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
GPDFAPLJ_00676 3.1e-193 yeaN P Transporter, major facilitator family protein
GPDFAPLJ_00677 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPDFAPLJ_00678 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPDFAPLJ_00679 6.1e-39
GPDFAPLJ_00680 0.0 lacS G Transporter
GPDFAPLJ_00681 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
GPDFAPLJ_00682 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPDFAPLJ_00683 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GPDFAPLJ_00684 2.2e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPDFAPLJ_00685 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPDFAPLJ_00686 8.8e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPDFAPLJ_00687 1.1e-62 rplQ J Ribosomal protein L17
GPDFAPLJ_00688 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPDFAPLJ_00689 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPDFAPLJ_00690 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPDFAPLJ_00691 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GPDFAPLJ_00692 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPDFAPLJ_00693 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GPDFAPLJ_00694 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GPDFAPLJ_00695 8.9e-64 rplO J Binds to the 23S rRNA
GPDFAPLJ_00696 2.9e-24 rpmD J Ribosomal protein L30
GPDFAPLJ_00697 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPDFAPLJ_00698 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPDFAPLJ_00699 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPDFAPLJ_00700 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPDFAPLJ_00701 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPDFAPLJ_00702 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPDFAPLJ_00703 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPDFAPLJ_00704 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPDFAPLJ_00705 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
GPDFAPLJ_00706 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPDFAPLJ_00707 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPDFAPLJ_00708 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPDFAPLJ_00709 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPDFAPLJ_00710 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPDFAPLJ_00711 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GPDFAPLJ_00712 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
GPDFAPLJ_00713 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPDFAPLJ_00714 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GPDFAPLJ_00715 8.8e-77 yphH S Cupin domain
GPDFAPLJ_00716 4.2e-72 yeaL S UPF0756 membrane protein
GPDFAPLJ_00717 6.9e-243 EGP Major facilitator Superfamily
GPDFAPLJ_00718 5e-75 copY K Copper transport repressor CopY TcrY
GPDFAPLJ_00719 8.5e-246 yhdP S Transporter associated domain
GPDFAPLJ_00720 0.0 ubiB S ABC1 family
GPDFAPLJ_00721 9.6e-144 S DUF218 domain
GPDFAPLJ_00722 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPDFAPLJ_00723 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPDFAPLJ_00724 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPDFAPLJ_00725 0.0 uvrA3 L excinuclease ABC, A subunit
GPDFAPLJ_00726 4.6e-123 S SNARE associated Golgi protein
GPDFAPLJ_00727 1.3e-229 N Uncharacterized conserved protein (DUF2075)
GPDFAPLJ_00728 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPDFAPLJ_00730 1e-254 yifK E Amino acid permease
GPDFAPLJ_00731 5.5e-158 endA V DNA/RNA non-specific endonuclease
GPDFAPLJ_00732 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPDFAPLJ_00733 1.3e-260 S Putative peptidoglycan binding domain
GPDFAPLJ_00735 7.2e-79 2.7.13.3 T GHKL domain
GPDFAPLJ_00736 4.8e-132 ponA V Beta-lactamase enzyme family
GPDFAPLJ_00737 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
GPDFAPLJ_00738 5.3e-215 uhpT EGP Major facilitator Superfamily
GPDFAPLJ_00739 2.6e-255 ytjP 3.5.1.18 E Dipeptidase
GPDFAPLJ_00740 8.2e-274 arcD S C4-dicarboxylate anaerobic carrier
GPDFAPLJ_00741 4.3e-25 UW LPXTG-motif cell wall anchor domain protein
GPDFAPLJ_00742 3e-75
GPDFAPLJ_00743 1.5e-17 NU Mycoplasma protein of unknown function, DUF285
GPDFAPLJ_00745 1.2e-157 metQ_4 P Belongs to the nlpA lipoprotein family
GPDFAPLJ_00746 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GPDFAPLJ_00747 1.2e-64 O Zinc-dependent metalloprotease
GPDFAPLJ_00748 4.7e-111 S Membrane
GPDFAPLJ_00749 1.2e-152 EG EamA-like transporter family
GPDFAPLJ_00750 2.5e-118 L Integrase
GPDFAPLJ_00751 1.4e-158 rssA S Phospholipase, patatin family
GPDFAPLJ_00752 2.6e-242 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
GPDFAPLJ_00753 9.6e-200 xerS L Belongs to the 'phage' integrase family
GPDFAPLJ_00755 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPDFAPLJ_00756 4.2e-77 marR K Transcriptional regulator, MarR family
GPDFAPLJ_00757 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPDFAPLJ_00758 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPDFAPLJ_00759 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GPDFAPLJ_00760 4.2e-130 IQ reductase
GPDFAPLJ_00761 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPDFAPLJ_00762 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GPDFAPLJ_00763 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPDFAPLJ_00764 6.8e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
GPDFAPLJ_00765 7.7e-133 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPDFAPLJ_00766 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
GPDFAPLJ_00767 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GPDFAPLJ_00772 3.3e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
GPDFAPLJ_00773 2.5e-139 L hmm pf00665
GPDFAPLJ_00774 7.2e-96 L Helix-turn-helix domain
GPDFAPLJ_00775 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GPDFAPLJ_00776 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
GPDFAPLJ_00777 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GPDFAPLJ_00778 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
GPDFAPLJ_00779 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
GPDFAPLJ_00780 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
GPDFAPLJ_00781 2.8e-207 araR K Transcriptional regulator
GPDFAPLJ_00782 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GPDFAPLJ_00783 3.3e-46 gcvH E glycine cleavage
GPDFAPLJ_00784 4.1e-220 rodA D Belongs to the SEDS family
GPDFAPLJ_00785 1e-31 S Protein of unknown function (DUF2969)
GPDFAPLJ_00786 1.9e-178 mbl D Cell shape determining protein MreB Mrl
GPDFAPLJ_00787 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPDFAPLJ_00788 1.3e-33 ywzB S Protein of unknown function (DUF1146)
GPDFAPLJ_00789 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GPDFAPLJ_00790 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPDFAPLJ_00791 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPDFAPLJ_00792 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPDFAPLJ_00793 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPDFAPLJ_00794 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPDFAPLJ_00795 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPDFAPLJ_00796 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
GPDFAPLJ_00797 5e-232 pyrP F Permease
GPDFAPLJ_00798 6.3e-129 yibF S overlaps another CDS with the same product name
GPDFAPLJ_00799 9.9e-192 yibE S overlaps another CDS with the same product name
GPDFAPLJ_00800 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPDFAPLJ_00801 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPDFAPLJ_00802 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPDFAPLJ_00803 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GPDFAPLJ_00804 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GPDFAPLJ_00805 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPDFAPLJ_00806 6e-108 tdk 2.7.1.21 F thymidine kinase
GPDFAPLJ_00807 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
GPDFAPLJ_00808 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
GPDFAPLJ_00809 2.7e-223 arcD U Amino acid permease
GPDFAPLJ_00810 2e-261 E Arginine ornithine antiporter
GPDFAPLJ_00811 4.7e-79 argR K Regulates arginine biosynthesis genes
GPDFAPLJ_00812 4.1e-239 arcA 3.5.3.6 E Arginine
GPDFAPLJ_00813 3.9e-187 ampC V Beta-lactamase
GPDFAPLJ_00814 1.9e-32
GPDFAPLJ_00817 9.6e-92 tag 3.2.2.20 L glycosylase
GPDFAPLJ_00818 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPDFAPLJ_00819 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPDFAPLJ_00820 4.9e-41
GPDFAPLJ_00821 9.2e-303 ytgP S Polysaccharide biosynthesis protein
GPDFAPLJ_00822 2.2e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPDFAPLJ_00823 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
GPDFAPLJ_00824 1.2e-85 uspA T Belongs to the universal stress protein A family
GPDFAPLJ_00825 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPDFAPLJ_00826 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
GPDFAPLJ_00827 3.8e-113
GPDFAPLJ_00828 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
GPDFAPLJ_00829 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPDFAPLJ_00830 2.1e-32
GPDFAPLJ_00831 2.6e-118 S CAAX protease self-immunity
GPDFAPLJ_00832 1.9e-43
GPDFAPLJ_00834 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPDFAPLJ_00835 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GPDFAPLJ_00836 1.2e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
GPDFAPLJ_00837 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GPDFAPLJ_00838 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
GPDFAPLJ_00839 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
GPDFAPLJ_00840 1.8e-43
GPDFAPLJ_00841 3.3e-40
GPDFAPLJ_00843 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPDFAPLJ_00844 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPDFAPLJ_00845 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GPDFAPLJ_00846 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPDFAPLJ_00847 3.5e-40 yheA S Belongs to the UPF0342 family
GPDFAPLJ_00848 1.8e-220 yhaO L Ser Thr phosphatase family protein
GPDFAPLJ_00849 0.0 L AAA domain
GPDFAPLJ_00850 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GPDFAPLJ_00852 1.2e-76 hit FG histidine triad
GPDFAPLJ_00853 3.9e-136 ecsA V ABC transporter, ATP-binding protein
GPDFAPLJ_00854 5.1e-218 ecsB U ABC transporter
GPDFAPLJ_00855 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GPDFAPLJ_00856 7.7e-27 S YSIRK type signal peptide
GPDFAPLJ_00857 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
GPDFAPLJ_00858 4e-254 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
GPDFAPLJ_00859 6.7e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
GPDFAPLJ_00860 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
GPDFAPLJ_00861 1.1e-183 iolS C Aldo keto reductase
GPDFAPLJ_00862 2.6e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
GPDFAPLJ_00863 7.5e-58 ytzB S Small secreted protein
GPDFAPLJ_00864 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GPDFAPLJ_00865 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPDFAPLJ_00866 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
GPDFAPLJ_00867 1.5e-35 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GPDFAPLJ_00868 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GPDFAPLJ_00869 1.9e-119 ybhL S Belongs to the BI1 family
GPDFAPLJ_00870 4.1e-116 yoaK S Protein of unknown function (DUF1275)
GPDFAPLJ_00871 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPDFAPLJ_00872 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GPDFAPLJ_00873 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPDFAPLJ_00874 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPDFAPLJ_00875 1.4e-203 dnaB L replication initiation and membrane attachment
GPDFAPLJ_00876 1.1e-170 dnaI L Primosomal protein DnaI
GPDFAPLJ_00877 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPDFAPLJ_00878 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GPDFAPLJ_00879 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPDFAPLJ_00880 1.8e-95 yqeG S HAD phosphatase, family IIIA
GPDFAPLJ_00881 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
GPDFAPLJ_00882 1.9e-47 yhbY J RNA-binding protein
GPDFAPLJ_00883 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPDFAPLJ_00884 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
GPDFAPLJ_00885 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GPDFAPLJ_00886 1.7e-139 yqeM Q Methyltransferase
GPDFAPLJ_00887 6.1e-213 ylbM S Belongs to the UPF0348 family
GPDFAPLJ_00888 2.9e-99 yceD S Uncharacterized ACR, COG1399
GPDFAPLJ_00889 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GPDFAPLJ_00890 1.5e-121 K response regulator
GPDFAPLJ_00891 4.1e-278 arlS 2.7.13.3 T Histidine kinase
GPDFAPLJ_00892 7.4e-267 yjeM E Amino Acid
GPDFAPLJ_00893 4.4e-231 V MatE
GPDFAPLJ_00894 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GPDFAPLJ_00895 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPDFAPLJ_00896 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GPDFAPLJ_00897 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPDFAPLJ_00898 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPDFAPLJ_00899 2e-58 yodB K Transcriptional regulator, HxlR family
GPDFAPLJ_00900 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPDFAPLJ_00901 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPDFAPLJ_00902 8.1e-114 rlpA M PFAM NLP P60 protein
GPDFAPLJ_00903 1.6e-117 udk 2.7.1.48 F Cytidine monophosphokinase
GPDFAPLJ_00904 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPDFAPLJ_00905 5.5e-280 O Arylsulfotransferase (ASST)
GPDFAPLJ_00906 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GPDFAPLJ_00907 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPDFAPLJ_00908 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPDFAPLJ_00909 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPDFAPLJ_00910 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPDFAPLJ_00911 9.3e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GPDFAPLJ_00912 9.8e-67 yabR J RNA binding
GPDFAPLJ_00913 3.3e-56 divIC D Septum formation initiator
GPDFAPLJ_00914 8.1e-39 yabO J S4 domain protein
GPDFAPLJ_00915 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPDFAPLJ_00916 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GPDFAPLJ_00917 4e-113 S (CBS) domain
GPDFAPLJ_00918 3.1e-147 tesE Q hydratase
GPDFAPLJ_00919 4.7e-243 codA 3.5.4.1 F cytosine deaminase
GPDFAPLJ_00920 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
GPDFAPLJ_00921 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
GPDFAPLJ_00922 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPDFAPLJ_00923 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GPDFAPLJ_00925 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPDFAPLJ_00926 2.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
GPDFAPLJ_00927 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPDFAPLJ_00928 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPDFAPLJ_00929 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPDFAPLJ_00931 6e-14 ard S Antirestriction protein (ArdA)
GPDFAPLJ_00943 4.8e-09
GPDFAPLJ_00945 3.3e-21 relB L Addiction module antitoxin, RelB DinJ family
GPDFAPLJ_00946 1.1e-21
GPDFAPLJ_00951 3.7e-20 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GPDFAPLJ_00952 3.5e-35
GPDFAPLJ_00959 6.4e-35
GPDFAPLJ_00962 3.7e-71 D CobQ CobB MinD ParA nucleotide binding domain protein
GPDFAPLJ_00963 7e-17 S Replication initiator protein A (RepA) N-terminus
GPDFAPLJ_00968 8.6e-17
GPDFAPLJ_00969 4.4e-09 gp17a S Terminase-like family
GPDFAPLJ_00970 1.4e-26 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L Participates in initiation and elongation during chromosome replication
GPDFAPLJ_00971 4e-137 gp17a S Terminase-like family
GPDFAPLJ_00972 1.1e-34
GPDFAPLJ_00973 2.6e-50
GPDFAPLJ_00975 1.2e-60
GPDFAPLJ_00976 8.6e-154 tnpB L Putative transposase DNA-binding domain
GPDFAPLJ_00982 9e-28
GPDFAPLJ_00983 1.8e-56
GPDFAPLJ_00984 2.6e-20
GPDFAPLJ_00986 1.3e-07
GPDFAPLJ_00988 1.4e-11 hol S COG5546 Small integral membrane protein
GPDFAPLJ_00991 4.7e-79 xerH L Belongs to the 'phage' integrase family
GPDFAPLJ_00992 1.1e-51 D Phage-related minor tail protein
GPDFAPLJ_00994 2.7e-52
GPDFAPLJ_00995 1.9e-67
GPDFAPLJ_00996 9.2e-106 fliC N bacterial-type flagellum-dependent cell motility
GPDFAPLJ_00997 3.6e-09
GPDFAPLJ_01000 3.8e-08
GPDFAPLJ_01001 3.7e-68 S regulation of transcription, DNA-dependent
GPDFAPLJ_01002 1.9e-112 S Glycosyl hydrolases family 25
GPDFAPLJ_01003 4.3e-70 S regulation of transcription, DNA-dependent
GPDFAPLJ_01004 6.5e-36 S DNA primase activity
GPDFAPLJ_01005 6.9e-42 S PD-(D/E)XK nuclease superfamily
GPDFAPLJ_01006 1.9e-27 S sequence-specific DNA binding transcription factor activity
GPDFAPLJ_01007 5.6e-227 dnaE_2 2.7.7.7 L DNA polymerase
GPDFAPLJ_01008 1.4e-155 L transposase, IS605 OrfB family
GPDFAPLJ_01010 8.2e-63 S DNA ligase (ATP) activity
GPDFAPLJ_01012 3e-31 S Protein of unknown function (DUF1064)
GPDFAPLJ_01020 2.6e-13
GPDFAPLJ_01024 8.8e-34 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
GPDFAPLJ_01026 2e-50 tdk 2.7.1.21 F Thymidine kinase
GPDFAPLJ_01027 1.9e-32 lytE M LysM domain protein
GPDFAPLJ_01028 4e-83 L Integrase
GPDFAPLJ_01033 1.4e-17
GPDFAPLJ_01034 2e-117 yeeA V Type II restriction enzyme, methylase subunits
GPDFAPLJ_01035 1.7e-18 ybjQ S Belongs to the UPF0145 family
GPDFAPLJ_01045 3.1e-25
GPDFAPLJ_01046 4.2e-75 ntd 2.4.2.6 F Nucleoside
GPDFAPLJ_01058 4.3e-31 L NUMOD4 motif
GPDFAPLJ_01060 1.5e-82 dck 2.7.1.74 F Deoxynucleoside kinase
GPDFAPLJ_01064 4.6e-101 L transposase, IS605 OrfB family
GPDFAPLJ_01068 8.5e-09 nrdH O Glutaredoxin
GPDFAPLJ_01069 3.1e-91 S nicotinamide riboside transmembrane transporter activity
GPDFAPLJ_01071 3.1e-78 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
GPDFAPLJ_01074 2.2e-121 recD 3.1.11.5 L Helix-hairpin-helix containing domain
GPDFAPLJ_01077 7.2e-97 3.6.4.12 L DnaB-like helicase C terminal domain
GPDFAPLJ_01079 7.5e-32
GPDFAPLJ_01080 1.6e-61
GPDFAPLJ_01081 4.3e-21 L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPDFAPLJ_01082 9.7e-17
GPDFAPLJ_01084 1.5e-10 2.7.1.24 H dephospho-CoA kinase activity
GPDFAPLJ_01086 1.7e-81 L Belongs to the 'phage' integrase family
GPDFAPLJ_01087 1.4e-124 yciB M ErfK YbiS YcfS YnhG
GPDFAPLJ_01089 2.5e-101
GPDFAPLJ_01090 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPDFAPLJ_01091 7.5e-123 S Alpha beta hydrolase
GPDFAPLJ_01092 1.7e-207 gldA 1.1.1.6 C dehydrogenase
GPDFAPLJ_01093 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GPDFAPLJ_01094 1.3e-41
GPDFAPLJ_01095 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
GPDFAPLJ_01096 1.4e-284 S C4-dicarboxylate anaerobic carrier
GPDFAPLJ_01097 1.8e-251 nhaC C Na H antiporter NhaC
GPDFAPLJ_01098 1.6e-241 pbuX F xanthine permease
GPDFAPLJ_01099 1.4e-283 pipD E Dipeptidase
GPDFAPLJ_01100 7e-289 L Transposase
GPDFAPLJ_01101 8.2e-168 corA P CorA-like Mg2+ transporter protein
GPDFAPLJ_01102 2.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPDFAPLJ_01103 2.3e-131 terC P membrane
GPDFAPLJ_01104 2.1e-54 trxA O Belongs to the thioredoxin family
GPDFAPLJ_01105 1.6e-236 mepA V MATE efflux family protein
GPDFAPLJ_01106 6.2e-76 K Transcriptional regulator, TetR family
GPDFAPLJ_01107 2.2e-72
GPDFAPLJ_01108 4.8e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
GPDFAPLJ_01109 7.9e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
GPDFAPLJ_01110 2.4e-277 M domain protein
GPDFAPLJ_01111 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
GPDFAPLJ_01112 3.8e-188 G Major Facilitator
GPDFAPLJ_01113 4.5e-49 G Major Facilitator
GPDFAPLJ_01114 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GPDFAPLJ_01115 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPDFAPLJ_01116 3e-259 G Major Facilitator
GPDFAPLJ_01117 2.4e-181 K Transcriptional regulator, LacI family
GPDFAPLJ_01118 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPDFAPLJ_01120 1.2e-100 nqr 1.5.1.36 S reductase
GPDFAPLJ_01121 6.1e-198 XK27_09615 S reductase
GPDFAPLJ_01122 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GPDFAPLJ_01123 1.5e-80 C Flavodoxin
GPDFAPLJ_01124 1.1e-60 K LysR substrate binding domain protein
GPDFAPLJ_01125 5.9e-163 1.1.1.346 C Aldo keto reductase
GPDFAPLJ_01126 2.1e-39 gcvR T Belongs to the UPF0237 family
GPDFAPLJ_01127 1.1e-240 XK27_08635 S UPF0210 protein
GPDFAPLJ_01128 7.6e-94 K Acetyltransferase (GNAT) domain
GPDFAPLJ_01129 1.2e-160 S Alpha beta hydrolase
GPDFAPLJ_01130 1.1e-158 gspA M family 8
GPDFAPLJ_01131 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPDFAPLJ_01132 1.1e-92
GPDFAPLJ_01133 1.9e-161 degV S EDD domain protein, DegV family
GPDFAPLJ_01134 0.0 FbpA K Fibronectin-binding protein
GPDFAPLJ_01135 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GPDFAPLJ_01136 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
GPDFAPLJ_01137 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPDFAPLJ_01138 1.3e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPDFAPLJ_01139 1.5e-65 esbA S Family of unknown function (DUF5322)
GPDFAPLJ_01140 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
GPDFAPLJ_01141 1.2e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GPDFAPLJ_01142 3.2e-83 F Belongs to the NrdI family
GPDFAPLJ_01145 4.2e-55 M Leucine-rich repeat (LRR) protein
GPDFAPLJ_01146 6.8e-56 K Transcriptional regulator, ArsR family
GPDFAPLJ_01147 1.2e-92 P Cadmium resistance transporter
GPDFAPLJ_01148 1.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
GPDFAPLJ_01149 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
GPDFAPLJ_01150 2.2e-182 ABC-SBP S ABC transporter
GPDFAPLJ_01151 8.5e-73 M PFAM NLP P60 protein
GPDFAPLJ_01152 9.8e-169 L Transposase and inactivated derivatives IS30 family
GPDFAPLJ_01153 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GPDFAPLJ_01154 5.5e-40 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPDFAPLJ_01155 8.4e-156 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPDFAPLJ_01156 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
GPDFAPLJ_01157 1.1e-90 bioY S BioY family
GPDFAPLJ_01158 1.5e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GPDFAPLJ_01159 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
GPDFAPLJ_01160 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPDFAPLJ_01161 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GPDFAPLJ_01162 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPDFAPLJ_01163 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
GPDFAPLJ_01164 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GPDFAPLJ_01165 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GPDFAPLJ_01166 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GPDFAPLJ_01167 1.9e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GPDFAPLJ_01168 1.2e-219 patA 2.6.1.1 E Aminotransferase
GPDFAPLJ_01169 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
GPDFAPLJ_01170 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPDFAPLJ_01171 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GPDFAPLJ_01172 3e-30 S Protein of unknown function (DUF2929)
GPDFAPLJ_01173 0.0 dnaE 2.7.7.7 L DNA polymerase
GPDFAPLJ_01174 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GPDFAPLJ_01175 2.3e-167 cvfB S S1 domain
GPDFAPLJ_01176 1.2e-163 xerD D recombinase XerD
GPDFAPLJ_01177 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPDFAPLJ_01178 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GPDFAPLJ_01179 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GPDFAPLJ_01180 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPDFAPLJ_01181 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPDFAPLJ_01182 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
GPDFAPLJ_01183 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
GPDFAPLJ_01184 8.5e-14 M Lysin motif
GPDFAPLJ_01185 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GPDFAPLJ_01186 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
GPDFAPLJ_01187 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GPDFAPLJ_01188 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPDFAPLJ_01189 1.5e-236 S Tetratricopeptide repeat protein
GPDFAPLJ_01190 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPDFAPLJ_01191 0.0 yfmR S ABC transporter, ATP-binding protein
GPDFAPLJ_01192 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPDFAPLJ_01193 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPDFAPLJ_01194 5.3e-113 hlyIII S protein, hemolysin III
GPDFAPLJ_01195 1.7e-151 DegV S EDD domain protein, DegV family
GPDFAPLJ_01196 9.5e-172 ypmR E lipolytic protein G-D-S-L family
GPDFAPLJ_01197 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
GPDFAPLJ_01198 4.4e-35 yozE S Belongs to the UPF0346 family
GPDFAPLJ_01199 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPDFAPLJ_01200 7.9e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPDFAPLJ_01201 2.4e-161 dprA LU DNA protecting protein DprA
GPDFAPLJ_01202 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPDFAPLJ_01203 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
GPDFAPLJ_01204 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GPDFAPLJ_01205 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPDFAPLJ_01206 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPDFAPLJ_01207 1.7e-84 F NUDIX domain
GPDFAPLJ_01208 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
GPDFAPLJ_01209 2.9e-82
GPDFAPLJ_01210 1.5e-288 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPDFAPLJ_01211 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GPDFAPLJ_01212 0.0 yjbQ P TrkA C-terminal domain protein
GPDFAPLJ_01213 4.9e-273 pipD E Dipeptidase
GPDFAPLJ_01214 0.0 trxB2 1.8.1.9 C Thioredoxin domain
GPDFAPLJ_01215 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
GPDFAPLJ_01216 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GPDFAPLJ_01217 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
GPDFAPLJ_01220 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPDFAPLJ_01221 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
GPDFAPLJ_01222 2.4e-223 mdtG EGP Major facilitator Superfamily
GPDFAPLJ_01223 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GPDFAPLJ_01224 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
GPDFAPLJ_01225 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPDFAPLJ_01226 8e-141
GPDFAPLJ_01227 2.2e-243 ydaM M Glycosyl transferase
GPDFAPLJ_01228 4.8e-218 G Glycosyl hydrolases family 8
GPDFAPLJ_01229 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GPDFAPLJ_01230 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
GPDFAPLJ_01231 1.7e-238 ktrB P Potassium uptake protein
GPDFAPLJ_01232 1.4e-116 ktrA P domain protein
GPDFAPLJ_01233 1.2e-81 Q Methyltransferase
GPDFAPLJ_01234 3.1e-229 mntH P H( )-stimulated, divalent metal cation uptake system
GPDFAPLJ_01235 5.7e-82 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GPDFAPLJ_01236 2.6e-68 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GPDFAPLJ_01237 7.4e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPDFAPLJ_01238 1.3e-96 S NADPH-dependent FMN reductase
GPDFAPLJ_01239 1.8e-220 G Belongs to the glycosyl hydrolase family 6
GPDFAPLJ_01240 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
GPDFAPLJ_01241 3.5e-134 I alpha/beta hydrolase fold
GPDFAPLJ_01242 7.5e-168 lsa S ABC transporter
GPDFAPLJ_01243 8.6e-59 lsa S ABC transporter
GPDFAPLJ_01244 3.8e-60 S Uncharacterised protein family (UPF0236)
GPDFAPLJ_01245 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GPDFAPLJ_01246 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPDFAPLJ_01247 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPDFAPLJ_01248 3.4e-35 nrdH O Glutaredoxin
GPDFAPLJ_01249 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GPDFAPLJ_01250 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPDFAPLJ_01251 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPDFAPLJ_01252 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPDFAPLJ_01253 9.7e-39 S Protein of unknown function (DUF2508)
GPDFAPLJ_01254 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPDFAPLJ_01255 7.6e-52 yaaQ S Cyclic-di-AMP receptor
GPDFAPLJ_01256 2.8e-185 holB 2.7.7.7 L DNA polymerase III
GPDFAPLJ_01257 5.9e-58 yabA L Involved in initiation control of chromosome replication
GPDFAPLJ_01258 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPDFAPLJ_01259 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
GPDFAPLJ_01260 7.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GPDFAPLJ_01261 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPDFAPLJ_01262 1.8e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GPDFAPLJ_01263 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPDFAPLJ_01271 1.2e-141 L Belongs to the 'phage' integrase family
GPDFAPLJ_01272 9.3e-121 S Domain of unknown function (DUF5067)
GPDFAPLJ_01273 7.1e-72
GPDFAPLJ_01275 2.7e-58 K Transcriptional regulator, Cro CI family
GPDFAPLJ_01276 1.8e-30 K Helix-turn-helix XRE-family like proteins
GPDFAPLJ_01277 8.8e-118 K ORF6N domain
GPDFAPLJ_01278 3.5e-36
GPDFAPLJ_01281 8.4e-31
GPDFAPLJ_01283 2.8e-82 S Siphovirus Gp157
GPDFAPLJ_01284 2.5e-08
GPDFAPLJ_01285 3.4e-258 res L Helicase C-terminal domain protein
GPDFAPLJ_01286 9.3e-141 L AAA domain
GPDFAPLJ_01287 1.7e-93
GPDFAPLJ_01288 4.2e-144 S Bifunctional DNA primase/polymerase, N-terminal
GPDFAPLJ_01289 2.3e-224 S Virulence-associated protein E
GPDFAPLJ_01291 8.8e-59 S VRR_NUC
GPDFAPLJ_01293 1.4e-10
GPDFAPLJ_01298 1.9e-72 arpU S Phage transcriptional regulator, ArpU family
GPDFAPLJ_01299 1.8e-61 L Terminase small subunit
GPDFAPLJ_01300 4.4e-09 S Phage terminase, large subunit
GPDFAPLJ_01301 9.7e-222 S Phage terminase, large subunit
GPDFAPLJ_01302 9.5e-272 S Phage portal protein
GPDFAPLJ_01303 4.1e-238 S Phage Mu protein F like protein
GPDFAPLJ_01305 6.3e-33 S YjcQ protein
GPDFAPLJ_01306 7.7e-102 S Domain of unknown function (DUF4355)
GPDFAPLJ_01307 2.9e-154
GPDFAPLJ_01308 2.1e-64 S Phage gp6-like head-tail connector protein
GPDFAPLJ_01309 1.3e-43
GPDFAPLJ_01310 3.6e-67 S Bacteriophage HK97-gp10, putative tail-component
GPDFAPLJ_01311 3.4e-22 S Protein of unknown function (DUF3168)
GPDFAPLJ_01312 9.1e-104 S Phage tail tube protein
GPDFAPLJ_01313 4.2e-53 S Phage tail assembly chaperone protein, TAC
GPDFAPLJ_01314 2.7e-61
GPDFAPLJ_01315 1.3e-255 sca1 D Phage tail tape measure protein
GPDFAPLJ_01316 6.1e-148 S phage tail
GPDFAPLJ_01317 0.0 M Prophage endopeptidase tail
GPDFAPLJ_01319 0.0 cotH M CotH kinase protein
GPDFAPLJ_01321 3.2e-33
GPDFAPLJ_01322 1.3e-56 S Bacteriophage holin of superfamily 6 (Holin_LLH)
GPDFAPLJ_01323 3.5e-181 3.5.1.104 M hydrolase, family 25
GPDFAPLJ_01324 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
GPDFAPLJ_01325 1.5e-237 lmrB EGP Major facilitator Superfamily
GPDFAPLJ_01326 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GPDFAPLJ_01327 1.7e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPDFAPLJ_01328 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
GPDFAPLJ_01329 2.6e-80 lytE M LysM domain protein
GPDFAPLJ_01330 0.0 oppD EP Psort location Cytoplasmic, score
GPDFAPLJ_01331 2.3e-93 lytE M LysM domain protein
GPDFAPLJ_01332 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
GPDFAPLJ_01333 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GPDFAPLJ_01334 1.2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
GPDFAPLJ_01335 8.1e-154 yeaE S Aldo keto
GPDFAPLJ_01336 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
GPDFAPLJ_01337 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
GPDFAPLJ_01338 2.9e-78 S Psort location Cytoplasmic, score
GPDFAPLJ_01339 7.7e-86 S Short repeat of unknown function (DUF308)
GPDFAPLJ_01340 1e-23
GPDFAPLJ_01341 2.8e-102 V VanZ like family
GPDFAPLJ_01342 4.8e-233 cycA E Amino acid permease
GPDFAPLJ_01343 4.3e-85 perR P Belongs to the Fur family
GPDFAPLJ_01344 1.5e-253 EGP Major facilitator Superfamily
GPDFAPLJ_01345 3.8e-60 S Uncharacterised protein family (UPF0236)
GPDFAPLJ_01346 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
GPDFAPLJ_01347 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPDFAPLJ_01348 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPDFAPLJ_01349 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GPDFAPLJ_01350 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GPDFAPLJ_01351 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GPDFAPLJ_01352 2.8e-31 yajC U Preprotein translocase
GPDFAPLJ_01353 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
GPDFAPLJ_01354 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GPDFAPLJ_01355 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPDFAPLJ_01356 4.1e-43 yrzL S Belongs to the UPF0297 family
GPDFAPLJ_01357 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPDFAPLJ_01358 6.1e-48 yrzB S Belongs to the UPF0473 family
GPDFAPLJ_01359 1e-85 cvpA S Colicin V production protein
GPDFAPLJ_01360 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPDFAPLJ_01361 6.1e-54 trxA O Belongs to the thioredoxin family
GPDFAPLJ_01362 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPDFAPLJ_01363 9.7e-173
GPDFAPLJ_01364 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPDFAPLJ_01365 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
GPDFAPLJ_01366 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GPDFAPLJ_01367 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPDFAPLJ_01368 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GPDFAPLJ_01369 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPDFAPLJ_01370 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPDFAPLJ_01371 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPDFAPLJ_01372 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPDFAPLJ_01373 9.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GPDFAPLJ_01374 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPDFAPLJ_01375 3.1e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPDFAPLJ_01376 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPDFAPLJ_01377 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
GPDFAPLJ_01378 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GPDFAPLJ_01379 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GPDFAPLJ_01380 4.9e-177 K AI-2E family transporter
GPDFAPLJ_01381 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
GPDFAPLJ_01382 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPDFAPLJ_01383 5.1e-116 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
GPDFAPLJ_01384 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPDFAPLJ_01385 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GPDFAPLJ_01386 3.3e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GPDFAPLJ_01387 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GPDFAPLJ_01388 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GPDFAPLJ_01389 7.4e-134 K LysR substrate binding domain
GPDFAPLJ_01390 2e-48 L PFAM transposase IS200-family protein
GPDFAPLJ_01391 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
GPDFAPLJ_01392 1.5e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPDFAPLJ_01393 0.0 asnB 6.3.5.4 E Asparagine synthase
GPDFAPLJ_01394 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GPDFAPLJ_01395 8.7e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPDFAPLJ_01396 9.7e-130 jag S R3H domain protein
GPDFAPLJ_01397 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPDFAPLJ_01398 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GPDFAPLJ_01399 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GPDFAPLJ_01400 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPDFAPLJ_01401 9.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPDFAPLJ_01402 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
GPDFAPLJ_01403 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
GPDFAPLJ_01404 1.7e-34 yaaA S S4 domain protein YaaA
GPDFAPLJ_01405 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPDFAPLJ_01406 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPDFAPLJ_01407 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPDFAPLJ_01408 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
GPDFAPLJ_01409 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPDFAPLJ_01410 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPDFAPLJ_01411 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GPDFAPLJ_01412 2e-74 rplI J Binds to the 23S rRNA
GPDFAPLJ_01413 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GPDFAPLJ_01414 9.9e-206 yttB EGP Major facilitator Superfamily
GPDFAPLJ_01415 3.7e-54
GPDFAPLJ_01416 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
GPDFAPLJ_01417 9.8e-09 K DNA-binding helix-turn-helix protein
GPDFAPLJ_01418 2.3e-78 O Bacterial dnaA protein
GPDFAPLJ_01419 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
GPDFAPLJ_01420 1.8e-267 frdC 1.3.5.4 C FAD binding domain
GPDFAPLJ_01421 1.4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GPDFAPLJ_01422 7.4e-305 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
GPDFAPLJ_01423 1.9e-161 mleR K LysR family
GPDFAPLJ_01424 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPDFAPLJ_01425 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
GPDFAPLJ_01426 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
GPDFAPLJ_01427 7.2e-169 L transposase, IS605 OrfB family
GPDFAPLJ_01428 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
GPDFAPLJ_01429 1.5e-25
GPDFAPLJ_01430 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GPDFAPLJ_01431 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPDFAPLJ_01432 4.7e-157 EG EamA-like transporter family
GPDFAPLJ_01433 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GPDFAPLJ_01434 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
GPDFAPLJ_01435 1.5e-225 S cog cog1373
GPDFAPLJ_01437 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GPDFAPLJ_01438 4.9e-224 oxlT P Major Facilitator Superfamily
GPDFAPLJ_01439 1.1e-158 spoU 2.1.1.185 J Methyltransferase
GPDFAPLJ_01440 2e-87 S Glycosyltransferase like family
GPDFAPLJ_01441 1.4e-83 M Domain of unknown function (DUF4422)
GPDFAPLJ_01442 4.1e-41 M biosynthesis protein
GPDFAPLJ_01443 1.4e-95 cps3F
GPDFAPLJ_01444 5.9e-97 M Glycosyltransferase like family 2
GPDFAPLJ_01445 2.1e-116 S Glycosyltransferase like family 2
GPDFAPLJ_01446 2.2e-75 rgpB GT2 M Glycosyl transferase family 2
GPDFAPLJ_01447 4.8e-215 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
GPDFAPLJ_01448 2.8e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
GPDFAPLJ_01449 0.0 ganB 3.2.1.89 G arabinogalactan
GPDFAPLJ_01450 2.1e-25
GPDFAPLJ_01451 0.0 G Peptidase_C39 like family
GPDFAPLJ_01452 5.8e-64
GPDFAPLJ_01453 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GPDFAPLJ_01454 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPDFAPLJ_01455 0.0 dnaK O Heat shock 70 kDa protein
GPDFAPLJ_01456 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GPDFAPLJ_01457 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GPDFAPLJ_01458 5.1e-223 3.6.4.12 L Belongs to the 'phage' integrase family
GPDFAPLJ_01460 6.5e-47
GPDFAPLJ_01463 7e-16
GPDFAPLJ_01465 1.8e-79 3.4.21.88 K Peptidase S24-like
GPDFAPLJ_01466 2.8e-10 K Helix-turn-helix XRE-family like proteins
GPDFAPLJ_01470 8e-15
GPDFAPLJ_01473 5.3e-119 L DnaD domain protein
GPDFAPLJ_01474 2.2e-190 L Belongs to the 'phage' integrase family
GPDFAPLJ_01475 4.4e-123 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
GPDFAPLJ_01477 1.3e-67
GPDFAPLJ_01478 3.6e-129
GPDFAPLJ_01483 1.9e-83 arpU S Phage transcriptional regulator, ArpU family
GPDFAPLJ_01485 1.2e-08
GPDFAPLJ_01486 2.8e-154 L HNH nucleases
GPDFAPLJ_01487 1.3e-76 terS L Phage terminase, small subunit
GPDFAPLJ_01488 0.0 terL S overlaps another CDS with the same product name
GPDFAPLJ_01490 2.6e-212 S Phage portal protein
GPDFAPLJ_01491 2.4e-113 pi136 S Caudovirus prohead serine protease
GPDFAPLJ_01492 5.9e-208 S Phage capsid family
GPDFAPLJ_01493 1.1e-63 S Phage gp6-like head-tail connector protein
GPDFAPLJ_01494 2.5e-39 S Phage head-tail joining protein
GPDFAPLJ_01495 7.2e-62 S Bacteriophage HK97-gp10, putative tail-component
GPDFAPLJ_01496 4.9e-75
GPDFAPLJ_01497 2.2e-116
GPDFAPLJ_01498 4.6e-58
GPDFAPLJ_01499 4.6e-24
GPDFAPLJ_01500 0.0 M Phage tail tape measure protein TP901
GPDFAPLJ_01501 4.1e-158 S Phage tail protein
GPDFAPLJ_01502 9.5e-259 3.4.24.40 M Peptidase family M23
GPDFAPLJ_01504 0.0 cotH M CotH kinase protein
GPDFAPLJ_01510 5.3e-15
GPDFAPLJ_01511 9.8e-63 S Bacteriophage holin of superfamily 6 (Holin_LLH)
GPDFAPLJ_01512 3.2e-198 3.5.1.104 M hydrolase, family 25
GPDFAPLJ_01513 2e-30
GPDFAPLJ_01514 1.5e-89 K IrrE N-terminal-like domain
GPDFAPLJ_01515 4.1e-275 pipD E Dipeptidase
GPDFAPLJ_01516 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
GPDFAPLJ_01518 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPDFAPLJ_01520 2.8e-57
GPDFAPLJ_01521 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
GPDFAPLJ_01522 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GPDFAPLJ_01523 1.2e-52
GPDFAPLJ_01524 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPDFAPLJ_01525 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPDFAPLJ_01526 1e-164 yniA G Phosphotransferase enzyme family
GPDFAPLJ_01527 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GPDFAPLJ_01528 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPDFAPLJ_01529 5.9e-264 glnPH2 P ABC transporter permease
GPDFAPLJ_01530 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GPDFAPLJ_01531 3.8e-70 yqeY S YqeY-like protein
GPDFAPLJ_01532 4.6e-38
GPDFAPLJ_01533 0.0 yhcA V ABC transporter, ATP-binding protein
GPDFAPLJ_01534 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
GPDFAPLJ_01535 2.1e-183 hrtB V ABC transporter permease
GPDFAPLJ_01536 7.5e-86 ygfC K transcriptional regulator (TetR family)
GPDFAPLJ_01537 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
GPDFAPLJ_01538 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
GPDFAPLJ_01539 3e-34
GPDFAPLJ_01540 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPDFAPLJ_01541 4.5e-160 L hmm pf00665
GPDFAPLJ_01542 4.4e-100 L Helix-turn-helix domain
GPDFAPLJ_01543 1.9e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPDFAPLJ_01544 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
GPDFAPLJ_01545 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GPDFAPLJ_01546 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GPDFAPLJ_01547 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GPDFAPLJ_01548 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPDFAPLJ_01549 1.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GPDFAPLJ_01550 5.5e-217 patA 2.6.1.1 E Aminotransferase
GPDFAPLJ_01551 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPDFAPLJ_01552 8.5e-84 KT Putative sugar diacid recognition
GPDFAPLJ_01553 2.2e-219 EG GntP family permease
GPDFAPLJ_01554 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GPDFAPLJ_01555 7.7e-58
GPDFAPLJ_01557 3.2e-134 mltD CBM50 M NlpC P60 family protein
GPDFAPLJ_01558 5.7e-29
GPDFAPLJ_01559 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
GPDFAPLJ_01560 9.8e-32 ykzG S Belongs to the UPF0356 family
GPDFAPLJ_01561 2.4e-78
GPDFAPLJ_01562 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPDFAPLJ_01563 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GPDFAPLJ_01564 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
GPDFAPLJ_01565 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPDFAPLJ_01566 1.2e-274 lpdA 1.8.1.4 C Dehydrogenase
GPDFAPLJ_01567 1.4e-47 yktA S Belongs to the UPF0223 family
GPDFAPLJ_01568 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GPDFAPLJ_01569 0.0 typA T GTP-binding protein TypA
GPDFAPLJ_01570 3.5e-222 ftsW D Belongs to the SEDS family
GPDFAPLJ_01571 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
GPDFAPLJ_01572 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
GPDFAPLJ_01573 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPDFAPLJ_01574 4.3e-197 ylbL T Belongs to the peptidase S16 family
GPDFAPLJ_01575 2.6e-80 comEA L Competence protein ComEA
GPDFAPLJ_01576 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
GPDFAPLJ_01577 0.0 comEC S Competence protein ComEC
GPDFAPLJ_01578 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
GPDFAPLJ_01579 1.1e-34 rpsT J Binds directly to 16S ribosomal RNA
GPDFAPLJ_01580 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPDFAPLJ_01581 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPDFAPLJ_01582 3.5e-163 S Tetratricopeptide repeat
GPDFAPLJ_01583 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPDFAPLJ_01584 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GPDFAPLJ_01585 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPDFAPLJ_01586 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
GPDFAPLJ_01587 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
GPDFAPLJ_01588 3.5e-35
GPDFAPLJ_01589 2.5e-212 bacI V MacB-like periplasmic core domain
GPDFAPLJ_01590 7.7e-126 V ABC transporter
GPDFAPLJ_01591 9.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPDFAPLJ_01592 8.9e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
GPDFAPLJ_01593 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPDFAPLJ_01594 2.7e-148 E Glyoxalase-like domain
GPDFAPLJ_01595 7.5e-155 glcU U sugar transport
GPDFAPLJ_01596 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
GPDFAPLJ_01597 2.2e-96 S reductase
GPDFAPLJ_01598 1.4e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPDFAPLJ_01599 1.7e-179 ABC-SBP S ABC transporter
GPDFAPLJ_01600 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
GPDFAPLJ_01601 2.5e-215 htrA 3.4.21.107 O serine protease
GPDFAPLJ_01602 4.5e-154 vicX 3.1.26.11 S domain protein
GPDFAPLJ_01603 2.7e-149 yycI S YycH protein
GPDFAPLJ_01604 2.1e-246 yycH S YycH protein
GPDFAPLJ_01605 0.0 vicK 2.7.13.3 T Histidine kinase
GPDFAPLJ_01606 6.8e-130 K response regulator
GPDFAPLJ_01608 5.2e-309 lmrA 3.6.3.44 V ABC transporter
GPDFAPLJ_01609 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
GPDFAPLJ_01611 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPDFAPLJ_01612 1.3e-08
GPDFAPLJ_01613 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPDFAPLJ_01614 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPDFAPLJ_01615 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GPDFAPLJ_01616 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPDFAPLJ_01617 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GPDFAPLJ_01618 7.8e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPDFAPLJ_01619 2.1e-87
GPDFAPLJ_01621 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPDFAPLJ_01622 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
GPDFAPLJ_01623 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPDFAPLJ_01624 1.3e-35 ynzC S UPF0291 protein
GPDFAPLJ_01625 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
GPDFAPLJ_01626 1e-116 plsC 2.3.1.51 I Acyltransferase
GPDFAPLJ_01627 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
GPDFAPLJ_01628 5.4e-49 yazA L GIY-YIG catalytic domain protein
GPDFAPLJ_01629 9.8e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPDFAPLJ_01630 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
GPDFAPLJ_01631 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPDFAPLJ_01632 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GPDFAPLJ_01633 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GPDFAPLJ_01634 3.5e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPDFAPLJ_01635 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
GPDFAPLJ_01636 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GPDFAPLJ_01637 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GPDFAPLJ_01638 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPDFAPLJ_01639 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
GPDFAPLJ_01640 6.8e-215 nusA K Participates in both transcription termination and antitermination
GPDFAPLJ_01641 1e-44 ylxR K Protein of unknown function (DUF448)
GPDFAPLJ_01642 4.5e-49 ylxQ J ribosomal protein
GPDFAPLJ_01643 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPDFAPLJ_01644 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPDFAPLJ_01645 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPDFAPLJ_01646 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GPDFAPLJ_01647 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPDFAPLJ_01648 4.9e-36 Q pyridine nucleotide-disulphide oxidoreductase
GPDFAPLJ_01649 0.0 helD 3.6.4.12 L DNA helicase
GPDFAPLJ_01650 3.4e-115 dedA S SNARE associated Golgi protein
GPDFAPLJ_01651 4.2e-126 3.1.3.73 G phosphoglycerate mutase
GPDFAPLJ_01652 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPDFAPLJ_01653 6.6e-35 S Transglycosylase associated protein
GPDFAPLJ_01655 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPDFAPLJ_01656 3.2e-226 V domain protein
GPDFAPLJ_01657 1.6e-94 K Transcriptional regulator (TetR family)
GPDFAPLJ_01658 9.8e-39 pspC KT positive regulation of macromolecule biosynthetic process
GPDFAPLJ_01659 2e-152
GPDFAPLJ_01660 4e-17 3.2.1.14 GH18
GPDFAPLJ_01661 1.5e-82 zur P Belongs to the Fur family
GPDFAPLJ_01662 5.8e-103 gmk2 2.7.4.8 F Guanylate kinase
GPDFAPLJ_01663 2.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
GPDFAPLJ_01664 3e-254 yfnA E Amino Acid
GPDFAPLJ_01665 3.6e-233 EGP Sugar (and other) transporter
GPDFAPLJ_01666 3.7e-43
GPDFAPLJ_01667 1.8e-108
GPDFAPLJ_01668 4.7e-207 potD P ABC transporter
GPDFAPLJ_01669 4.9e-140 potC P ABC transporter permease
GPDFAPLJ_01670 4.5e-146 potB P ABC transporter permease
GPDFAPLJ_01671 1.7e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GPDFAPLJ_01672 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GPDFAPLJ_01673 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
GPDFAPLJ_01674 0.0 pacL 3.6.3.8 P P-type ATPase
GPDFAPLJ_01675 3.4e-85 dps P Belongs to the Dps family
GPDFAPLJ_01676 2.8e-255 yagE E amino acid
GPDFAPLJ_01677 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
GPDFAPLJ_01678 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPDFAPLJ_01679 2.7e-149 L hmm pf00665
GPDFAPLJ_01680 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
GPDFAPLJ_01681 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
GPDFAPLJ_01682 2.5e-138 IQ KR domain
GPDFAPLJ_01683 5.6e-133 S membrane transporter protein
GPDFAPLJ_01684 3e-96 S ABC-type cobalt transport system, permease component
GPDFAPLJ_01685 1e-246 cbiO1 S ABC transporter, ATP-binding protein
GPDFAPLJ_01686 4.5e-112 P Cobalt transport protein
GPDFAPLJ_01687 1.6e-52 yvlA
GPDFAPLJ_01688 0.0 yjcE P Sodium proton antiporter
GPDFAPLJ_01689 2.2e-52 ypaA S Protein of unknown function (DUF1304)
GPDFAPLJ_01690 8.2e-190 D Alpha beta
GPDFAPLJ_01691 1e-72 K Transcriptional regulator
GPDFAPLJ_01692 1.1e-161
GPDFAPLJ_01693 2.4e-167 1.6.5.5 C Zinc-binding dehydrogenase
GPDFAPLJ_01694 1.3e-257 G PTS system Galactitol-specific IIC component
GPDFAPLJ_01695 1.4e-212 EGP Major facilitator Superfamily
GPDFAPLJ_01696 5.2e-14
GPDFAPLJ_01697 7.1e-63
GPDFAPLJ_01698 2.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
GPDFAPLJ_01699 5.1e-81 uspA T universal stress protein
GPDFAPLJ_01700 0.0 tetP J elongation factor G
GPDFAPLJ_01701 5.2e-167 GK ROK family
GPDFAPLJ_01702 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
GPDFAPLJ_01703 4.5e-140 aroD S Serine hydrolase (FSH1)
GPDFAPLJ_01704 2.7e-244 yagE E amino acid
GPDFAPLJ_01705 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GPDFAPLJ_01706 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
GPDFAPLJ_01707 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPDFAPLJ_01708 1.1e-283 pipD E Dipeptidase
GPDFAPLJ_01709 0.0 yfiC V ABC transporter
GPDFAPLJ_01710 2.4e-309 lmrA V ABC transporter, ATP-binding protein
GPDFAPLJ_01711 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPDFAPLJ_01712 6e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GPDFAPLJ_01713 9.8e-169 L Transposase and inactivated derivatives IS30 family
GPDFAPLJ_01714 6.5e-165 czcD P cation diffusion facilitator family transporter
GPDFAPLJ_01715 2.4e-124 sirR K iron dependent repressor
GPDFAPLJ_01716 3.5e-31 cspC K Cold shock protein
GPDFAPLJ_01717 3.6e-129 thrE S Putative threonine/serine exporter
GPDFAPLJ_01718 6.7e-81 S Threonine/Serine exporter, ThrE
GPDFAPLJ_01719 2.7e-120 lssY 3.6.1.27 I phosphatase
GPDFAPLJ_01720 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
GPDFAPLJ_01721 1.5e-275 lysP E amino acid
GPDFAPLJ_01722 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GPDFAPLJ_01728 4.8e-131 S Hydrolases of the alpha beta superfamily
GPDFAPLJ_01729 1.3e-16 S Hydrolases of the alpha beta superfamily
GPDFAPLJ_01730 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
GPDFAPLJ_01731 3.4e-77 ctsR K Belongs to the CtsR family
GPDFAPLJ_01732 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GPDFAPLJ_01733 1e-110 K Bacterial regulatory proteins, tetR family
GPDFAPLJ_01734 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPDFAPLJ_01735 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPDFAPLJ_01736 6.5e-202 ykiI
GPDFAPLJ_01737 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
GPDFAPLJ_01738 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPDFAPLJ_01739 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GPDFAPLJ_01740 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPDFAPLJ_01741 9.8e-169 L Transposase and inactivated derivatives IS30 family
GPDFAPLJ_01742 8.2e-48
GPDFAPLJ_01743 7.8e-272 S ABC transporter, ATP-binding protein
GPDFAPLJ_01744 2.3e-142 S Putative ABC-transporter type IV
GPDFAPLJ_01745 2e-106 NU mannosyl-glycoprotein
GPDFAPLJ_01746 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
GPDFAPLJ_01747 3.3e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
GPDFAPLJ_01748 7.6e-205 nrnB S DHHA1 domain
GPDFAPLJ_01750 6.9e-49
GPDFAPLJ_01751 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPDFAPLJ_01752 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPDFAPLJ_01753 2e-15 S Domain of unknown function (DUF4767)
GPDFAPLJ_01754 9.5e-55
GPDFAPLJ_01755 2.9e-117 yrkL S Flavodoxin-like fold
GPDFAPLJ_01757 1.6e-64 yeaO S Protein of unknown function, DUF488
GPDFAPLJ_01758 6.3e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GPDFAPLJ_01759 3e-204 3.1.3.1 S associated with various cellular activities
GPDFAPLJ_01760 9.3e-242 S Putative metallopeptidase domain
GPDFAPLJ_01761 5.1e-47
GPDFAPLJ_01762 0.0 pepO 3.4.24.71 O Peptidase family M13
GPDFAPLJ_01763 3.2e-110 K Helix-turn-helix domain
GPDFAPLJ_01764 5.6e-86 ymdB S Macro domain protein
GPDFAPLJ_01765 2.1e-197 EGP Major facilitator Superfamily
GPDFAPLJ_01766 4.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPDFAPLJ_01767 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPDFAPLJ_01768 5.3e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
GPDFAPLJ_01769 0.0 ysaB V FtsX-like permease family
GPDFAPLJ_01770 2.1e-132 macB2 V ABC transporter, ATP-binding protein
GPDFAPLJ_01771 3.8e-179 T PhoQ Sensor
GPDFAPLJ_01772 1.2e-123 K response regulator
GPDFAPLJ_01773 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
GPDFAPLJ_01774 8.9e-136 pnuC H nicotinamide mononucleotide transporter
GPDFAPLJ_01775 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPDFAPLJ_01776 2.3e-204
GPDFAPLJ_01777 2.6e-52
GPDFAPLJ_01778 9.1e-36
GPDFAPLJ_01779 2.4e-92 yxkA S Phosphatidylethanolamine-binding protein
GPDFAPLJ_01780 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
GPDFAPLJ_01781 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
GPDFAPLJ_01782 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPDFAPLJ_01783 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GPDFAPLJ_01784 2e-180 galR K Transcriptional regulator
GPDFAPLJ_01785 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
GPDFAPLJ_01786 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPDFAPLJ_01787 1.5e-80 K AsnC family
GPDFAPLJ_01788 1.5e-80 uspA T universal stress protein
GPDFAPLJ_01789 1.1e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
GPDFAPLJ_01790 9.8e-169 L Transposase and inactivated derivatives IS30 family
GPDFAPLJ_01791 1.6e-115 S membrane
GPDFAPLJ_01792 8.4e-109 S VIT family
GPDFAPLJ_01793 5.5e-83 usp1 T Belongs to the universal stress protein A family
GPDFAPLJ_01794 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPDFAPLJ_01795 1.4e-150 glnH ET ABC transporter
GPDFAPLJ_01796 4.2e-110 gluC P ABC transporter permease
GPDFAPLJ_01797 1.4e-108 glnP P ABC transporter permease
GPDFAPLJ_01798 1.5e-217 S CAAX protease self-immunity
GPDFAPLJ_01799 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPDFAPLJ_01800 2.5e-53
GPDFAPLJ_01801 4.9e-73 merR K MerR HTH family regulatory protein
GPDFAPLJ_01802 1e-268 lmrB EGP Major facilitator Superfamily
GPDFAPLJ_01803 2e-116 S Domain of unknown function (DUF4811)
GPDFAPLJ_01804 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GPDFAPLJ_01806 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPDFAPLJ_01807 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
GPDFAPLJ_01808 3.4e-188 I Alpha beta
GPDFAPLJ_01809 8.5e-282 emrY EGP Major facilitator Superfamily
GPDFAPLJ_01810 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
GPDFAPLJ_01811 2e-250 yjjP S Putative threonine/serine exporter
GPDFAPLJ_01812 1e-159 mleR K LysR family
GPDFAPLJ_01813 1.7e-254 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPDFAPLJ_01814 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
GPDFAPLJ_01815 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPDFAPLJ_01816 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
GPDFAPLJ_01817 4.7e-114 yjbH Q Thioredoxin
GPDFAPLJ_01818 9.2e-264 pipD E Dipeptidase
GPDFAPLJ_01819 3e-203 coiA 3.6.4.12 S Competence protein
GPDFAPLJ_01820 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GPDFAPLJ_01821 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GPDFAPLJ_01822 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GPDFAPLJ_01823 3.8e-60 S Uncharacterised protein family (UPF0236)
GPDFAPLJ_01824 2e-48 L PFAM transposase IS200-family protein
GPDFAPLJ_01825 8.8e-71 yneR S Belongs to the HesB IscA family
GPDFAPLJ_01826 0.0 S membrane
GPDFAPLJ_01827 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
GPDFAPLJ_01828 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPDFAPLJ_01829 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPDFAPLJ_01830 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
GPDFAPLJ_01831 1.4e-26 gluP 3.4.21.105 S Peptidase, S54 family
GPDFAPLJ_01832 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
GPDFAPLJ_01833 5.6e-183 glk 2.7.1.2 G Glucokinase
GPDFAPLJ_01834 3.4e-67 yqhL P Rhodanese-like protein
GPDFAPLJ_01835 1.3e-21 S Protein of unknown function (DUF3042)
GPDFAPLJ_01836 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPDFAPLJ_01837 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
GPDFAPLJ_01838 3.8e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPDFAPLJ_01839 6.3e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GPDFAPLJ_01840 3.9e-12
GPDFAPLJ_01841 1.7e-146 P Belongs to the nlpA lipoprotein family
GPDFAPLJ_01842 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPDFAPLJ_01843 3.7e-51 S Iron-sulfur cluster assembly protein
GPDFAPLJ_01844 1e-151
GPDFAPLJ_01845 6.6e-174
GPDFAPLJ_01846 7.2e-89 dut S Protein conserved in bacteria
GPDFAPLJ_01849 1.8e-110 K Transcriptional regulator
GPDFAPLJ_01850 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
GPDFAPLJ_01851 1.6e-54 ysxB J Cysteine protease Prp
GPDFAPLJ_01852 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GPDFAPLJ_01853 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPDFAPLJ_01854 5.1e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GPDFAPLJ_01855 1.9e-113 J 2'-5' RNA ligase superfamily
GPDFAPLJ_01856 2.2e-70 yqhY S Asp23 family, cell envelope-related function
GPDFAPLJ_01857 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPDFAPLJ_01858 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPDFAPLJ_01859 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPDFAPLJ_01860 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPDFAPLJ_01861 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPDFAPLJ_01862 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GPDFAPLJ_01863 8.1e-76 argR K Regulates arginine biosynthesis genes
GPDFAPLJ_01864 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
GPDFAPLJ_01865 2.4e-53
GPDFAPLJ_01866 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GPDFAPLJ_01867 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GPDFAPLJ_01868 1.2e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPDFAPLJ_01869 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPDFAPLJ_01870 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPDFAPLJ_01871 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPDFAPLJ_01872 3.8e-131 stp 3.1.3.16 T phosphatase
GPDFAPLJ_01873 0.0 KLT serine threonine protein kinase
GPDFAPLJ_01874 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GPDFAPLJ_01875 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GPDFAPLJ_01876 1.6e-114 thiN 2.7.6.2 H thiamine pyrophosphokinase
GPDFAPLJ_01877 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GPDFAPLJ_01878 4.7e-58 asp S Asp23 family, cell envelope-related function
GPDFAPLJ_01879 7.1e-311 yloV S DAK2 domain fusion protein YloV
GPDFAPLJ_01880 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPDFAPLJ_01881 6.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GPDFAPLJ_01882 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPDFAPLJ_01883 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GPDFAPLJ_01884 0.0 smc D Required for chromosome condensation and partitioning
GPDFAPLJ_01885 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPDFAPLJ_01886 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GPDFAPLJ_01887 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPDFAPLJ_01888 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GPDFAPLJ_01889 1.3e-38 ylqC S Belongs to the UPF0109 family
GPDFAPLJ_01890 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPDFAPLJ_01891 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GPDFAPLJ_01892 9.9e-261 yfnA E amino acid
GPDFAPLJ_01893 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GPDFAPLJ_01894 2.9e-34
GPDFAPLJ_01895 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
GPDFAPLJ_01896 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
GPDFAPLJ_01897 3.3e-83
GPDFAPLJ_01898 5.9e-114 L PFAM Integrase catalytic region
GPDFAPLJ_01899 0.0 csd1 3.5.1.28 G domain, Protein
GPDFAPLJ_01900 5.6e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPDFAPLJ_01901 3.9e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPDFAPLJ_01902 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GPDFAPLJ_01903 7.5e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPDFAPLJ_01904 2.2e-36 S Domain of unknown function DUF1829
GPDFAPLJ_01905 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPDFAPLJ_01906 0.0 2.7.7.6 M Peptidase family M23
GPDFAPLJ_01907 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
GPDFAPLJ_01908 2.4e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
GPDFAPLJ_01909 3.3e-146 cps1D M Domain of unknown function (DUF4422)
GPDFAPLJ_01910 7.9e-127 recX 2.4.1.337 GT4 S Regulatory protein RecX
GPDFAPLJ_01911 4.9e-31
GPDFAPLJ_01912 6.6e-34 S Protein of unknown function (DUF2922)
GPDFAPLJ_01913 3.2e-153 yihY S Belongs to the UPF0761 family
GPDFAPLJ_01914 1.1e-281 yjeM E Amino Acid
GPDFAPLJ_01915 1e-254 E Arginine ornithine antiporter
GPDFAPLJ_01916 1.7e-220 arcT 2.6.1.1 E Aminotransferase
GPDFAPLJ_01917 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
GPDFAPLJ_01918 6.1e-79 fld C Flavodoxin
GPDFAPLJ_01919 2.3e-67 gtcA S Teichoic acid glycosylation protein
GPDFAPLJ_01920 9.3e-56
GPDFAPLJ_01921 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPDFAPLJ_01923 2.6e-228 yfmL L DEAD DEAH box helicase
GPDFAPLJ_01924 4.5e-191 mocA S Oxidoreductase
GPDFAPLJ_01925 9.1e-62 S Domain of unknown function (DUF4828)
GPDFAPLJ_01926 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
GPDFAPLJ_01927 3.8e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPDFAPLJ_01928 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GPDFAPLJ_01929 9.3e-197 S Protein of unknown function (DUF3114)
GPDFAPLJ_01930 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
GPDFAPLJ_01931 1.1e-119 ybhL S Belongs to the BI1 family
GPDFAPLJ_01932 3.1e-21
GPDFAPLJ_01933 1.4e-95 K Acetyltransferase (GNAT) family
GPDFAPLJ_01934 1e-75 K LytTr DNA-binding domain
GPDFAPLJ_01935 7.3e-69 S Protein of unknown function (DUF3021)
GPDFAPLJ_01936 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
GPDFAPLJ_01937 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
GPDFAPLJ_01938 2.6e-74 ogt 2.1.1.63 L Methyltransferase
GPDFAPLJ_01939 4.8e-122 pnb C nitroreductase
GPDFAPLJ_01940 2.1e-91
GPDFAPLJ_01941 1.4e-90 S B3 4 domain
GPDFAPLJ_01942 4e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
GPDFAPLJ_01943 1.5e-156 amtB P ammonium transporter
GPDFAPLJ_01944 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPDFAPLJ_01946 1.3e-46
GPDFAPLJ_01947 3.2e-96 S PFAM Archaeal ATPase
GPDFAPLJ_01948 4.5e-160 L hmm pf00665
GPDFAPLJ_01949 4.4e-100 L Helix-turn-helix domain
GPDFAPLJ_01951 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPDFAPLJ_01952 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GPDFAPLJ_01953 2.6e-118 S Repeat protein
GPDFAPLJ_01954 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
GPDFAPLJ_01955 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GPDFAPLJ_01956 3.7e-57 XK27_04120 S Putative amino acid metabolism
GPDFAPLJ_01957 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
GPDFAPLJ_01958 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPDFAPLJ_01960 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
GPDFAPLJ_01961 4.2e-32 cspA K Cold shock protein
GPDFAPLJ_01962 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPDFAPLJ_01963 1.9e-42 divIVA D DivIVA domain protein
GPDFAPLJ_01964 5.1e-142 ylmH S S4 domain protein
GPDFAPLJ_01965 3.2e-40 yggT S YGGT family
GPDFAPLJ_01966 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GPDFAPLJ_01967 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPDFAPLJ_01968 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GPDFAPLJ_01969 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GPDFAPLJ_01970 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPDFAPLJ_01971 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPDFAPLJ_01972 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPDFAPLJ_01973 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GPDFAPLJ_01974 2.6e-56 ftsL D Cell division protein FtsL
GPDFAPLJ_01975 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GPDFAPLJ_01976 3.1e-77 mraZ K Belongs to the MraZ family
GPDFAPLJ_01977 7.3e-56
GPDFAPLJ_01978 1.2e-10 S Protein of unknown function (DUF4044)
GPDFAPLJ_01979 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GPDFAPLJ_01980 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GPDFAPLJ_01981 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
GPDFAPLJ_01982 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GPDFAPLJ_01984 4.4e-100 L Helix-turn-helix domain
GPDFAPLJ_01985 4.5e-160 L hmm pf00665
GPDFAPLJ_01986 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPDFAPLJ_01987 1.2e-264 glnP P ABC transporter
GPDFAPLJ_01988 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPDFAPLJ_01990 7.2e-221 cycA E Amino acid permease
GPDFAPLJ_01991 2.3e-218 nupG F Nucleoside transporter
GPDFAPLJ_01992 5.6e-169 rihC 3.2.2.1 F Nucleoside
GPDFAPLJ_01993 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
GPDFAPLJ_01994 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GPDFAPLJ_01995 4.3e-151 noc K Belongs to the ParB family
GPDFAPLJ_01996 3.9e-139 soj D Sporulation initiation inhibitor
GPDFAPLJ_01997 1.7e-154 spo0J K Belongs to the ParB family
GPDFAPLJ_01998 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
GPDFAPLJ_01999 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GPDFAPLJ_02000 2.6e-135 XK27_01040 S Protein of unknown function (DUF1129)
GPDFAPLJ_02001 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPDFAPLJ_02002 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPDFAPLJ_02003 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
GPDFAPLJ_02004 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
GPDFAPLJ_02005 2.8e-171 deoR K sugar-binding domain protein
GPDFAPLJ_02006 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPDFAPLJ_02007 1.2e-123 K response regulator
GPDFAPLJ_02008 4.2e-198 hpk31 2.7.13.3 T Histidine kinase
GPDFAPLJ_02009 3.7e-136 azlC E AzlC protein
GPDFAPLJ_02010 1.6e-52 azlD S branched-chain amino acid
GPDFAPLJ_02011 4.1e-228 L transposase, IS605 OrfB family
GPDFAPLJ_02012 2.1e-60 L PFAM transposase IS200-family protein
GPDFAPLJ_02014 3.4e-250 mmuP E amino acid
GPDFAPLJ_02015 2e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
GPDFAPLJ_02016 1e-44
GPDFAPLJ_02018 1.8e-09

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)