ORF_ID e_value Gene_name EC_number CAZy COGs Description
NMFKLGDN_00001 3.9e-27 mleP3 S Membrane transport protein
NMFKLGDN_00002 7.3e-121 T Transcriptional regulatory protein, C terminal
NMFKLGDN_00003 1.7e-238 T GHKL domain
NMFKLGDN_00004 4.7e-109 S Peptidase propeptide and YPEB domain
NMFKLGDN_00005 1.7e-76 P FAD-binding domain
NMFKLGDN_00006 4.3e-55 yphJ 4.1.1.44 S decarboxylase
NMFKLGDN_00007 5.3e-83 K Bacterial regulatory proteins, tetR family
NMFKLGDN_00008 2e-75 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NMFKLGDN_00009 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
NMFKLGDN_00010 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
NMFKLGDN_00011 2.7e-85 C Flavodoxin
NMFKLGDN_00012 5.6e-158 K Transcriptional regulator
NMFKLGDN_00013 6.3e-88 lacA S transferase hexapeptide repeat
NMFKLGDN_00014 9.4e-32 S thiolester hydrolase activity
NMFKLGDN_00015 2e-152 S Alpha beta hydrolase
NMFKLGDN_00016 1.5e-92 padC Q Phenolic acid decarboxylase
NMFKLGDN_00017 3.3e-92 padR K Virulence activator alpha C-term
NMFKLGDN_00018 4.7e-66 GM NAD(P)H-binding
NMFKLGDN_00019 2.3e-155 ypuA S Protein of unknown function (DUF1002)
NMFKLGDN_00020 1.5e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
NMFKLGDN_00021 2.3e-57 K Transcriptional regulator
NMFKLGDN_00022 4.3e-40 K Transcriptional regulator
NMFKLGDN_00023 2.9e-162 akr5f 1.1.1.346 S reductase
NMFKLGDN_00024 1.5e-92 K Transcriptional regulator C-terminal region
NMFKLGDN_00025 2.1e-74 S membrane
NMFKLGDN_00026 6.1e-88 S membrane
NMFKLGDN_00027 1.2e-112 GM NAD(P)H-binding
NMFKLGDN_00028 1.1e-64 yneR
NMFKLGDN_00029 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
NMFKLGDN_00030 2.7e-51 L PFAM Integrase catalytic region
NMFKLGDN_00031 1.3e-103 3.1.21.3 L Type I restriction modification DNA specificity domain
NMFKLGDN_00032 4.6e-294 hsdM 2.1.1.72 V type I restriction-modification system
NMFKLGDN_00033 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NMFKLGDN_00034 6.2e-140 IQ reductase
NMFKLGDN_00035 2.8e-58 yhaI S Protein of unknown function (DUF805)
NMFKLGDN_00036 2.2e-44
NMFKLGDN_00037 0.0 nylA 3.5.1.4 J Belongs to the amidase family
NMFKLGDN_00038 4.2e-47
NMFKLGDN_00039 2.2e-96 K Acetyltransferase (GNAT) domain
NMFKLGDN_00040 1.4e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NMFKLGDN_00041 2.8e-57
NMFKLGDN_00042 5.9e-177 prmA J Ribosomal protein L11 methyltransferase
NMFKLGDN_00043 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NMFKLGDN_00044 1.1e-50
NMFKLGDN_00045 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMFKLGDN_00046 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NMFKLGDN_00047 1e-164 yniA G Phosphotransferase enzyme family
NMFKLGDN_00048 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NMFKLGDN_00049 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NMFKLGDN_00050 5.9e-264 glnPH2 P ABC transporter permease
NMFKLGDN_00051 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NMFKLGDN_00052 3.8e-70 yqeY S YqeY-like protein
NMFKLGDN_00053 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NMFKLGDN_00054 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMFKLGDN_00055 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMFKLGDN_00056 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMFKLGDN_00057 4.5e-49 ylxQ J ribosomal protein
NMFKLGDN_00058 1e-44 ylxR K Protein of unknown function (DUF448)
NMFKLGDN_00059 1e-215 nusA K Participates in both transcription termination and antitermination
NMFKLGDN_00060 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NMFKLGDN_00061 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMFKLGDN_00062 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NMFKLGDN_00063 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NMFKLGDN_00064 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
NMFKLGDN_00065 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMFKLGDN_00066 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NMFKLGDN_00067 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NMFKLGDN_00068 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMFKLGDN_00069 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
NMFKLGDN_00070 9.8e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMFKLGDN_00071 5.4e-49 yazA L GIY-YIG catalytic domain protein
NMFKLGDN_00072 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
NMFKLGDN_00073 4.6e-117 plsC 2.3.1.51 I Acyltransferase
NMFKLGDN_00074 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
NMFKLGDN_00075 1.3e-35 ynzC S UPF0291 protein
NMFKLGDN_00076 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NMFKLGDN_00077 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NMFKLGDN_00078 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMFKLGDN_00081 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
NMFKLGDN_00082 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NMFKLGDN_00083 1.8e-226 clcA_2 P Chloride transporter, ClC family
NMFKLGDN_00084 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMFKLGDN_00085 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMFKLGDN_00086 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMFKLGDN_00087 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NMFKLGDN_00088 9.8e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NMFKLGDN_00089 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMFKLGDN_00090 6e-108 tdk 2.7.1.21 F thymidine kinase
NMFKLGDN_00091 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NMFKLGDN_00092 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NMFKLGDN_00093 2.7e-223 arcD U Amino acid permease
NMFKLGDN_00094 2e-261 E Arginine ornithine antiporter
NMFKLGDN_00095 4.7e-79 argR K Regulates arginine biosynthesis genes
NMFKLGDN_00096 4.1e-239 arcA 3.5.3.6 E Arginine
NMFKLGDN_00097 3.9e-187 ampC V Beta-lactamase
NMFKLGDN_00098 1.9e-32
NMFKLGDN_00099 0.0 M domain protein
NMFKLGDN_00100 2.6e-91
NMFKLGDN_00102 3.2e-113 yjcE P Sodium proton antiporter
NMFKLGDN_00103 3.7e-18 yjcE P Sodium proton antiporter
NMFKLGDN_00104 3.8e-55 yjcE P Sodium proton antiporter
NMFKLGDN_00105 3e-23 S Protein of unknown function (DUF4065)
NMFKLGDN_00106 7.1e-43 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NMFKLGDN_00107 4.7e-25
NMFKLGDN_00109 3.4e-171 L Integrase core domain
NMFKLGDN_00110 1.9e-46 L Transposase
NMFKLGDN_00111 1.6e-70 L Belongs to the 'phage' integrase family
NMFKLGDN_00112 1.5e-33 ligA 2.7.7.7, 6.5.1.2 L EXOIII
NMFKLGDN_00113 5.2e-75 E IrrE N-terminal-like domain
NMFKLGDN_00114 1.6e-49 K Cro/C1-type HTH DNA-binding domain
NMFKLGDN_00115 1.3e-15 K Helix-turn-helix XRE-family like proteins
NMFKLGDN_00117 1.4e-64 S Protein of unknown function (DUF3102)
NMFKLGDN_00123 3.8e-07
NMFKLGDN_00125 7.6e-54 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMFKLGDN_00126 1e-130 S Putative HNHc nuclease
NMFKLGDN_00127 2.8e-22 L Psort location Cytoplasmic, score
NMFKLGDN_00128 3.4e-171 L Integrase core domain
NMFKLGDN_00129 1.9e-46 L Transposase
NMFKLGDN_00130 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NMFKLGDN_00131 9.4e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
NMFKLGDN_00132 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMFKLGDN_00133 2.7e-36 ykuJ S Protein of unknown function (DUF1797)
NMFKLGDN_00134 6.5e-105 L Helix-turn-helix domain
NMFKLGDN_00135 8.7e-140 L hmm pf00665
NMFKLGDN_00136 1.5e-17 NU Mycoplasma protein of unknown function, DUF285
NMFKLGDN_00138 1.2e-157 metQ_4 P Belongs to the nlpA lipoprotein family
NMFKLGDN_00139 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NMFKLGDN_00140 1.2e-64 O Zinc-dependent metalloprotease
NMFKLGDN_00141 9.5e-112 S Membrane
NMFKLGDN_00142 8.2e-60 M Peptidase_C39 like family
NMFKLGDN_00143 3.6e-68 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMFKLGDN_00144 1.5e-46 S integral membrane protein
NMFKLGDN_00145 1.9e-46 L Transposase
NMFKLGDN_00146 3.4e-171 L Integrase core domain
NMFKLGDN_00147 1.2e-25 czrA K Transcriptional regulator, ArsR family
NMFKLGDN_00148 4.6e-38
NMFKLGDN_00149 0.0 yhcA V ABC transporter, ATP-binding protein
NMFKLGDN_00150 2.3e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NMFKLGDN_00151 2.1e-183 hrtB V ABC transporter permease
NMFKLGDN_00152 2.6e-86 ygfC K transcriptional regulator (TetR family)
NMFKLGDN_00153 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NMFKLGDN_00154 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
NMFKLGDN_00155 3e-34
NMFKLGDN_00156 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMFKLGDN_00157 2.2e-75 L hmm pf00665
NMFKLGDN_00158 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NMFKLGDN_00159 2.1e-126
NMFKLGDN_00160 3.3e-55 S Sugar efflux transporter for intercellular exchange
NMFKLGDN_00161 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NMFKLGDN_00163 0.0 L Helicase C-terminal domain protein
NMFKLGDN_00164 6.9e-76 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
NMFKLGDN_00165 1.3e-176 S Aldo keto reductase
NMFKLGDN_00167 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMFKLGDN_00168 4.5e-62 psiE S Phosphate-starvation-inducible E
NMFKLGDN_00169 2.1e-102 ydeN S Serine hydrolase
NMFKLGDN_00171 3.4e-155 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMFKLGDN_00172 6.1e-255 nhaC C Na H antiporter NhaC
NMFKLGDN_00173 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
NMFKLGDN_00174 4.8e-114 ywnB S NAD(P)H-binding
NMFKLGDN_00175 9.2e-36
NMFKLGDN_00176 9.3e-130 IQ Dehydrogenase reductase
NMFKLGDN_00177 1.5e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NMFKLGDN_00179 5.5e-110 dedA S SNARE-like domain protein
NMFKLGDN_00180 2.6e-104 S Protein of unknown function (DUF1461)
NMFKLGDN_00181 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NMFKLGDN_00182 1.3e-93 yutD S Protein of unknown function (DUF1027)
NMFKLGDN_00183 2.2e-113 S Calcineurin-like phosphoesterase
NMFKLGDN_00184 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMFKLGDN_00185 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
NMFKLGDN_00187 6.3e-70
NMFKLGDN_00188 2.7e-40
NMFKLGDN_00189 8.3e-78 NU general secretion pathway protein
NMFKLGDN_00190 7.1e-47 comGC U competence protein ComGC
NMFKLGDN_00191 3.6e-180 comGB NU type II secretion system
NMFKLGDN_00192 1.7e-179 comGA NU Type II IV secretion system protein
NMFKLGDN_00193 3.5e-132 yebC K Transcriptional regulatory protein
NMFKLGDN_00194 5.5e-134
NMFKLGDN_00195 1.4e-181 ccpA K catabolite control protein A
NMFKLGDN_00196 1.2e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NMFKLGDN_00197 3.5e-26
NMFKLGDN_00198 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NMFKLGDN_00199 3.4e-147 ykuT M mechanosensitive ion channel
NMFKLGDN_00200 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NMFKLGDN_00201 3.6e-76 ykuL S (CBS) domain
NMFKLGDN_00202 4.4e-94 S Phosphoesterase
NMFKLGDN_00203 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMFKLGDN_00204 1.4e-142 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMFKLGDN_00205 1.5e-95 yslB S Protein of unknown function (DUF2507)
NMFKLGDN_00206 6.1e-54 trxA O Belongs to the thioredoxin family
NMFKLGDN_00207 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMFKLGDN_00208 1e-85 cvpA S Colicin V production protein
NMFKLGDN_00209 6.1e-48 yrzB S Belongs to the UPF0473 family
NMFKLGDN_00210 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMFKLGDN_00211 4.1e-43 yrzL S Belongs to the UPF0297 family
NMFKLGDN_00212 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMFKLGDN_00213 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NMFKLGDN_00214 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NMFKLGDN_00215 2.8e-31 yajC U Preprotein translocase
NMFKLGDN_00216 1.3e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NMFKLGDN_00217 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NMFKLGDN_00218 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NMFKLGDN_00219 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMFKLGDN_00220 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMFKLGDN_00221 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
NMFKLGDN_00222 3.8e-60 S Uncharacterised protein family (UPF0236)
NMFKLGDN_00223 5.9e-114 L PFAM Integrase catalytic region
NMFKLGDN_00224 1.6e-67 yqkB S Belongs to the HesB IscA family
NMFKLGDN_00225 2.7e-49
NMFKLGDN_00227 1.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NMFKLGDN_00228 1.3e-61 asp S Asp23 family, cell envelope-related function
NMFKLGDN_00229 2.1e-25
NMFKLGDN_00230 3.2e-95
NMFKLGDN_00231 2.8e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NMFKLGDN_00232 2e-183 K Transcriptional regulator, LacI family
NMFKLGDN_00233 2.2e-230 gntT EG Gluconate
NMFKLGDN_00234 5.9e-114 L PFAM Integrase catalytic region
NMFKLGDN_00235 9.2e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NMFKLGDN_00236 4.7e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NMFKLGDN_00237 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMFKLGDN_00238 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMFKLGDN_00239 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMFKLGDN_00240 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMFKLGDN_00241 2.3e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NMFKLGDN_00242 1.5e-191 mtnE 2.6.1.83 E Aminotransferase
NMFKLGDN_00243 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMFKLGDN_00244 0.0 uup S ABC transporter, ATP-binding protein
NMFKLGDN_00245 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMFKLGDN_00247 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMFKLGDN_00248 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMFKLGDN_00249 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
NMFKLGDN_00250 4.3e-305 ybeC E amino acid
NMFKLGDN_00251 0.0 ydaO E amino acid
NMFKLGDN_00252 1.2e-39
NMFKLGDN_00253 7.4e-68 rmaI K Transcriptional regulator
NMFKLGDN_00254 1.6e-236 EGP Major facilitator Superfamily
NMFKLGDN_00255 2.9e-111 yvyE 3.4.13.9 S YigZ family
NMFKLGDN_00256 1.4e-256 comFA L Helicase C-terminal domain protein
NMFKLGDN_00257 1.3e-114 comFC S Competence protein
NMFKLGDN_00258 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMFKLGDN_00259 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMFKLGDN_00260 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NMFKLGDN_00261 3.1e-32 KT PspC domain protein
NMFKLGDN_00262 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NMFKLGDN_00263 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMFKLGDN_00264 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMFKLGDN_00265 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NMFKLGDN_00266 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMFKLGDN_00267 3.9e-136 yrjD S LUD domain
NMFKLGDN_00268 7.5e-288 lutB C 4Fe-4S dicluster domain
NMFKLGDN_00269 3.5e-163 lutA C Cysteine-rich domain
NMFKLGDN_00270 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMFKLGDN_00271 2.5e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NMFKLGDN_00272 6.1e-33 aatB ET PFAM extracellular solute-binding protein, family 3
NMFKLGDN_00273 3.5e-103 aatB ET PFAM extracellular solute-binding protein, family 3
NMFKLGDN_00274 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
NMFKLGDN_00275 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NMFKLGDN_00276 2.3e-116 yfbR S HD containing hydrolase-like enzyme
NMFKLGDN_00277 1.5e-13
NMFKLGDN_00278 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NMFKLGDN_00279 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NMFKLGDN_00280 5.4e-245 steT E amino acid
NMFKLGDN_00281 1.1e-161 rapZ S Displays ATPase and GTPase activities
NMFKLGDN_00282 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NMFKLGDN_00283 4e-170 whiA K May be required for sporulation
NMFKLGDN_00285 8.8e-15
NMFKLGDN_00286 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NMFKLGDN_00288 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMFKLGDN_00289 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NMFKLGDN_00290 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMFKLGDN_00291 9.5e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMFKLGDN_00292 7.1e-248 yifK E Amino acid permease
NMFKLGDN_00293 7.6e-291 clcA P chloride
NMFKLGDN_00294 1.8e-34 secG U Preprotein translocase
NMFKLGDN_00295 7.5e-146 est 3.1.1.1 S Serine aminopeptidase, S33
NMFKLGDN_00296 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NMFKLGDN_00297 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NMFKLGDN_00298 6.3e-105 yxjI
NMFKLGDN_00299 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMFKLGDN_00300 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NMFKLGDN_00301 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NMFKLGDN_00302 2.6e-86 K Acetyltransferase (GNAT) domain
NMFKLGDN_00303 4.4e-76 S PAS domain
NMFKLGDN_00304 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
NMFKLGDN_00305 1.6e-168 murB 1.3.1.98 M Cell wall formation
NMFKLGDN_00306 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMFKLGDN_00307 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NMFKLGDN_00308 4.8e-249 fucP G Major Facilitator Superfamily
NMFKLGDN_00309 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMFKLGDN_00310 2e-126 ybbR S YbbR-like protein
NMFKLGDN_00311 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMFKLGDN_00312 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NMFKLGDN_00313 8.7e-53
NMFKLGDN_00314 0.0 oatA I Acyltransferase
NMFKLGDN_00315 2.3e-81 K Transcriptional regulator
NMFKLGDN_00316 7.5e-149 XK27_02985 S Cof-like hydrolase
NMFKLGDN_00317 2.8e-79 lytE M Lysin motif
NMFKLGDN_00319 1.5e-132 K response regulator
NMFKLGDN_00320 1.7e-271 yclK 2.7.13.3 T Histidine kinase
NMFKLGDN_00321 2.6e-155 glcU U sugar transport
NMFKLGDN_00322 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
NMFKLGDN_00323 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
NMFKLGDN_00324 1.3e-28
NMFKLGDN_00325 6.1e-216 xylR GK ROK family
NMFKLGDN_00327 4.3e-261 xylT EGP Major facilitator Superfamily
NMFKLGDN_00328 6.1e-57 rhaS2 K Transcriptional regulator, AraC family
NMFKLGDN_00329 5.9e-114 L PFAM Integrase catalytic region
NMFKLGDN_00330 2.7e-148 E Glyoxalase-like domain
NMFKLGDN_00331 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMFKLGDN_00332 2.3e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NMFKLGDN_00333 9.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMFKLGDN_00334 7.7e-126 V ABC transporter
NMFKLGDN_00335 2.5e-212 bacI V MacB-like periplasmic core domain
NMFKLGDN_00336 3.5e-35
NMFKLGDN_00337 5.9e-114 L PFAM Integrase catalytic region
NMFKLGDN_00338 3.4e-14 D nuclear chromosome segregation
NMFKLGDN_00339 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NMFKLGDN_00340 1.8e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NMFKLGDN_00341 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NMFKLGDN_00342 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NMFKLGDN_00343 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
NMFKLGDN_00344 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMFKLGDN_00345 5.9e-58 yabA L Involved in initiation control of chromosome replication
NMFKLGDN_00346 2.8e-185 holB 2.7.7.7 L DNA polymerase III
NMFKLGDN_00347 7.6e-52 yaaQ S Cyclic-di-AMP receptor
NMFKLGDN_00348 1.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMFKLGDN_00349 9.7e-39 S Protein of unknown function (DUF2508)
NMFKLGDN_00350 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMFKLGDN_00351 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMFKLGDN_00352 3.1e-291 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMFKLGDN_00353 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NMFKLGDN_00354 3.4e-35 nrdH O Glutaredoxin
NMFKLGDN_00355 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMFKLGDN_00356 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMFKLGDN_00357 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NMFKLGDN_00358 6.4e-126 S Putative adhesin
NMFKLGDN_00359 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
NMFKLGDN_00360 4e-56 K transcriptional regulator PadR family
NMFKLGDN_00361 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NMFKLGDN_00363 1.5e-48
NMFKLGDN_00364 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NMFKLGDN_00365 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMFKLGDN_00366 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NMFKLGDN_00367 6.2e-246 M Glycosyl transferase family group 2
NMFKLGDN_00369 1.3e-226 aadAT EK Aminotransferase, class I
NMFKLGDN_00370 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NMFKLGDN_00371 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMFKLGDN_00372 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
NMFKLGDN_00373 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NMFKLGDN_00374 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMFKLGDN_00375 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMFKLGDN_00376 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMFKLGDN_00377 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMFKLGDN_00378 1.7e-207 yacL S domain protein
NMFKLGDN_00379 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMFKLGDN_00380 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NMFKLGDN_00381 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
NMFKLGDN_00382 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NMFKLGDN_00383 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
NMFKLGDN_00384 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NMFKLGDN_00385 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NMFKLGDN_00386 2.4e-119 tcyB E ABC transporter
NMFKLGDN_00387 9.4e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMFKLGDN_00388 3.1e-169 I alpha/beta hydrolase fold
NMFKLGDN_00389 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NMFKLGDN_00390 0.0 S Bacterial membrane protein, YfhO
NMFKLGDN_00391 1.3e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NMFKLGDN_00392 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NMFKLGDN_00394 1.9e-85 ydcK S Belongs to the SprT family
NMFKLGDN_00395 0.0 yhgF K Tex-like protein N-terminal domain protein
NMFKLGDN_00396 5.1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NMFKLGDN_00397 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMFKLGDN_00398 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
NMFKLGDN_00399 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NMFKLGDN_00400 9.5e-300 aspT P Predicted Permease Membrane Region
NMFKLGDN_00401 2.8e-252 EGP Major facilitator Superfamily
NMFKLGDN_00402 5.5e-110
NMFKLGDN_00405 7e-158 yjjH S Calcineurin-like phosphoesterase
NMFKLGDN_00406 1.9e-262 dtpT U amino acid peptide transporter
NMFKLGDN_00407 3.7e-19
NMFKLGDN_00409 3.7e-91 yqiG C Oxidoreductase
NMFKLGDN_00410 7.8e-20 yqiG C Oxidoreductase
NMFKLGDN_00411 1.1e-50 yqiG C Oxidoreductase
NMFKLGDN_00412 8.5e-54 S macrophage migration inhibitory factor
NMFKLGDN_00413 2.4e-65 K HxlR-like helix-turn-helix
NMFKLGDN_00414 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMFKLGDN_00416 6.1e-224 L Transposase IS66 family
NMFKLGDN_00418 9.3e-78 pnuC H nicotinamide mononucleotide transporter
NMFKLGDN_00428 2.9e-126
NMFKLGDN_00429 8.8e-93 S LemA family
NMFKLGDN_00430 7.6e-158
NMFKLGDN_00431 1.9e-46 L Transposase
NMFKLGDN_00432 3.4e-171 L Integrase core domain
NMFKLGDN_00434 3.4e-97 L Belongs to the 'phage' integrase family
NMFKLGDN_00435 1e-17 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NMFKLGDN_00438 1.1e-30 lytE M Lysin motif
NMFKLGDN_00440 1.9e-62
NMFKLGDN_00442 2e-57 ruvB 3.6.4.12 L four-way junction helicase activity
NMFKLGDN_00443 1.7e-23 S YoeB-like toxin of bacterial type II toxin-antitoxin system
NMFKLGDN_00444 3.7e-25 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NMFKLGDN_00449 8.1e-16
NMFKLGDN_00450 1.7e-54 srtA 3.4.22.70 M sortase family
NMFKLGDN_00474 2.4e-19 L Psort location Cytoplasmic, score
NMFKLGDN_00476 4e-11 S Domain of unknown function (DUF771)
NMFKLGDN_00478 4.5e-15 S sequence-specific DNA binding
NMFKLGDN_00479 1.5e-08 E Zn peptidase
NMFKLGDN_00480 3.1e-92 L Belongs to the 'phage' integrase family
NMFKLGDN_00484 4.4e-34 XK27_00515 D Glucan-binding protein C
NMFKLGDN_00486 1.3e-53 L Protein of unknown function (DUF3991)
NMFKLGDN_00487 3.8e-136 topA2 5.99.1.2 G Topoisomerase IA
NMFKLGDN_00489 3.9e-148 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NMFKLGDN_00492 5.7e-06
NMFKLGDN_00494 2.6e-191 U TraM recognition site of TraD and TraG
NMFKLGDN_00495 2.3e-64
NMFKLGDN_00497 8.1e-24
NMFKLGDN_00498 6.8e-180 U type IV secretory pathway VirB4
NMFKLGDN_00500 1.4e-37 M CHAP domain
NMFKLGDN_00505 2.4e-24
NMFKLGDN_00507 3.5e-79 S Fic/DOC family
NMFKLGDN_00509 1.1e-20 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NMFKLGDN_00510 4.4e-29 S YoeB-like toxin of bacterial type II toxin-antitoxin system
NMFKLGDN_00513 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NMFKLGDN_00514 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
NMFKLGDN_00515 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NMFKLGDN_00516 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NMFKLGDN_00517 1.2e-10 S Protein of unknown function (DUF4044)
NMFKLGDN_00518 7.3e-56
NMFKLGDN_00519 3.1e-77 mraZ K Belongs to the MraZ family
NMFKLGDN_00520 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NMFKLGDN_00521 2.6e-56 ftsL D Cell division protein FtsL
NMFKLGDN_00522 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NMFKLGDN_00523 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMFKLGDN_00524 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMFKLGDN_00525 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMFKLGDN_00526 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NMFKLGDN_00527 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NMFKLGDN_00528 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMFKLGDN_00529 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NMFKLGDN_00530 3.2e-40 yggT S YGGT family
NMFKLGDN_00531 5.1e-142 ylmH S S4 domain protein
NMFKLGDN_00532 1.9e-42 divIVA D DivIVA domain protein
NMFKLGDN_00533 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMFKLGDN_00534 4.2e-32 cspA K Cold shock protein
NMFKLGDN_00535 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NMFKLGDN_00537 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMFKLGDN_00538 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
NMFKLGDN_00539 1.3e-57 XK27_04120 S Putative amino acid metabolism
NMFKLGDN_00540 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NMFKLGDN_00541 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NMFKLGDN_00542 9e-119 S Repeat protein
NMFKLGDN_00543 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMFKLGDN_00544 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMFKLGDN_00546 3.4e-132 O Bacterial dnaA protein
NMFKLGDN_00547 3.2e-236 L Integrase core domain
NMFKLGDN_00548 0.0 3.2.1.55 GH51 G Right handed beta helix region
NMFKLGDN_00549 1.6e-290 xynT G MFS/sugar transport protein
NMFKLGDN_00550 3.8e-102 rhaS2 K Transcriptional regulator, AraC family
NMFKLGDN_00551 3.4e-132 O Bacterial dnaA protein
NMFKLGDN_00552 3.2e-236 L Integrase core domain
NMFKLGDN_00553 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMFKLGDN_00554 5.5e-217 patA 2.6.1.1 E Aminotransferase
NMFKLGDN_00555 5.8e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NMFKLGDN_00556 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMFKLGDN_00557 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NMFKLGDN_00558 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NMFKLGDN_00559 5.1e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NMFKLGDN_00560 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NMFKLGDN_00561 1.9e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NMFKLGDN_00562 9.4e-17 UW LPXTG-motif cell wall anchor domain protein
NMFKLGDN_00563 2.2e-75 L hmm pf00665
NMFKLGDN_00564 3.2e-236 L Integrase core domain
NMFKLGDN_00565 3.4e-132 O Bacterial dnaA protein
NMFKLGDN_00566 3.6e-76 KT Putative sugar diacid recognition
NMFKLGDN_00567 1.7e-219 EG GntP family permease
NMFKLGDN_00568 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NMFKLGDN_00569 7.7e-58
NMFKLGDN_00571 1.2e-133 mltD CBM50 M NlpC P60 family protein
NMFKLGDN_00572 5.7e-29
NMFKLGDN_00573 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NMFKLGDN_00574 9.8e-32 ykzG S Belongs to the UPF0356 family
NMFKLGDN_00575 2.4e-78
NMFKLGDN_00577 2.1e-102 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NMFKLGDN_00578 4.5e-56 hol S COG5546 Small integral membrane protein
NMFKLGDN_00579 2.8e-30
NMFKLGDN_00581 1.5e-76
NMFKLGDN_00582 9.5e-70
NMFKLGDN_00583 2.1e-22 S GDSL-like Lipase/Acylhydrolase
NMFKLGDN_00586 3.2e-22 spoIVFA GT2,GT4 D peptidase
NMFKLGDN_00587 1.4e-206 M Prophage endopeptidase tail
NMFKLGDN_00588 2.6e-112 S Phage tail protein
NMFKLGDN_00589 0.0 M Phage tail tape measure protein TP901
NMFKLGDN_00590 6.2e-19
NMFKLGDN_00591 7.4e-68 S Phage tail tube protein
NMFKLGDN_00592 7.5e-25
NMFKLGDN_00593 3.3e-21
NMFKLGDN_00594 2.4e-38 S Phage head-tail joining protein
NMFKLGDN_00595 3.1e-43 S Phage gp6-like head-tail connector protein
NMFKLGDN_00596 1.5e-131 S Phage capsid family
NMFKLGDN_00597 7.3e-87 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NMFKLGDN_00598 2.9e-145 S portal protein
NMFKLGDN_00599 1.6e-268 S Phage Terminase
NMFKLGDN_00600 4.2e-80 L Phage terminase, small subunit
NMFKLGDN_00601 9.3e-53 L HNH nucleases
NMFKLGDN_00617 1.1e-45 pnuC H nicotinamide mononucleotide transporter
NMFKLGDN_00618 6.5e-105 L Helix-turn-helix domain
NMFKLGDN_00619 8.7e-140 L hmm pf00665
NMFKLGDN_00621 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
NMFKLGDN_00622 2.1e-310 lmrA 3.6.3.44 V ABC transporter
NMFKLGDN_00624 6.8e-130 K response regulator
NMFKLGDN_00625 0.0 vicK 2.7.13.3 T Histidine kinase
NMFKLGDN_00626 6.9e-245 yycH S YycH protein
NMFKLGDN_00627 2.7e-149 yycI S YycH protein
NMFKLGDN_00628 4.5e-154 vicX 3.1.26.11 S domain protein
NMFKLGDN_00629 2.4e-218 htrA 3.4.21.107 O serine protease
NMFKLGDN_00630 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NMFKLGDN_00631 4.7e-177 ABC-SBP S ABC transporter
NMFKLGDN_00632 5.2e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMFKLGDN_00634 6.4e-96 S reductase
NMFKLGDN_00635 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NMFKLGDN_00636 1.1e-108 S Peptidase, M23
NMFKLGDN_00637 1.2e-180 galR K Transcriptional regulator
NMFKLGDN_00638 1e-281 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NMFKLGDN_00639 5.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMFKLGDN_00640 7.6e-180 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NMFKLGDN_00641 2.6e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
NMFKLGDN_00642 1.8e-92 yxkA S Phosphatidylethanolamine-binding protein
NMFKLGDN_00643 3.4e-35
NMFKLGDN_00644 9.1e-53
NMFKLGDN_00645 8.7e-204
NMFKLGDN_00646 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMFKLGDN_00647 4.4e-135 pnuC H nicotinamide mononucleotide transporter
NMFKLGDN_00648 1.9e-155 ytbE 1.1.1.346 S Aldo keto reductase
NMFKLGDN_00649 1.2e-123 K response regulator
NMFKLGDN_00650 3.8e-179 T PhoQ Sensor
NMFKLGDN_00651 2.1e-132 macB2 V ABC transporter, ATP-binding protein
NMFKLGDN_00652 4.4e-78 ysaB V FtsX-like permease family
NMFKLGDN_00655 8.7e-140 L hmm pf00665
NMFKLGDN_00656 6.5e-105 L Helix-turn-helix domain
NMFKLGDN_00657 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NMFKLGDN_00658 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
NMFKLGDN_00659 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMFKLGDN_00660 2.9e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMFKLGDN_00661 1.5e-65 esbA S Family of unknown function (DUF5322)
NMFKLGDN_00662 4.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
NMFKLGDN_00663 2.8e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NMFKLGDN_00664 1.1e-83 F Belongs to the NrdI family
NMFKLGDN_00665 1.3e-47 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NMFKLGDN_00666 1.6e-105 ypsA S Belongs to the UPF0398 family
NMFKLGDN_00667 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMFKLGDN_00668 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NMFKLGDN_00669 2e-161 EG EamA-like transporter family
NMFKLGDN_00670 3e-125 dnaD L DnaD domain protein
NMFKLGDN_00671 2.9e-85 ypmB S Protein conserved in bacteria
NMFKLGDN_00672 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NMFKLGDN_00673 2e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NMFKLGDN_00674 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NMFKLGDN_00675 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NMFKLGDN_00676 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NMFKLGDN_00677 1.4e-86 S Protein of unknown function (DUF1440)
NMFKLGDN_00678 0.0 rafA 3.2.1.22 G alpha-galactosidase
NMFKLGDN_00679 4.2e-189 galR K Periplasmic binding protein-like domain
NMFKLGDN_00680 7.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NMFKLGDN_00681 1.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMFKLGDN_00682 2.6e-124 lrgB M LrgB-like family
NMFKLGDN_00683 1.9e-66 lrgA S LrgA family
NMFKLGDN_00684 1.2e-129 lytT K response regulator receiver
NMFKLGDN_00685 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NMFKLGDN_00686 4e-148 f42a O Band 7 protein
NMFKLGDN_00687 1e-259 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NMFKLGDN_00688 2.2e-156 yitU 3.1.3.104 S hydrolase
NMFKLGDN_00689 9.2e-39 S Cytochrome B5
NMFKLGDN_00690 7e-113 nreC K PFAM regulatory protein LuxR
NMFKLGDN_00691 3.2e-161 hipB K Helix-turn-helix
NMFKLGDN_00692 2.8e-57 yitW S Iron-sulfur cluster assembly protein
NMFKLGDN_00693 1.6e-271 sufB O assembly protein SufB
NMFKLGDN_00694 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
NMFKLGDN_00695 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMFKLGDN_00696 7.3e-239 sufD O FeS assembly protein SufD
NMFKLGDN_00697 6.5e-145 sufC O FeS assembly ATPase SufC
NMFKLGDN_00698 4.2e-32 feoA P FeoA domain
NMFKLGDN_00699 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NMFKLGDN_00700 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NMFKLGDN_00701 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NMFKLGDN_00702 3.5e-64 ydiI Q Thioesterase superfamily
NMFKLGDN_00703 2.4e-109 yvrI K sigma factor activity
NMFKLGDN_00704 5e-202 G Transporter, major facilitator family protein
NMFKLGDN_00705 0.0 S Bacterial membrane protein YfhO
NMFKLGDN_00706 5.2e-101 T Ion transport 2 domain protein
NMFKLGDN_00707 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NMFKLGDN_00708 8.9e-56 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NMFKLGDN_00709 1.7e-153 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NMFKLGDN_00710 1.2e-95 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NMFKLGDN_00711 5.3e-195 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMFKLGDN_00712 1.2e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NMFKLGDN_00713 3.3e-230 L transposase, IS605 OrfB family
NMFKLGDN_00714 2.1e-60 L PFAM transposase IS200-family protein
NMFKLGDN_00716 0.0 L PLD-like domain
NMFKLGDN_00717 1.4e-88 mrr L restriction endonuclease
NMFKLGDN_00718 3.1e-151 L restriction endonuclease
NMFKLGDN_00719 1.9e-46 L Transposase
NMFKLGDN_00720 3.4e-171 L Integrase core domain
NMFKLGDN_00721 8.7e-140 L hmm pf00665
NMFKLGDN_00722 6.5e-105 L Helix-turn-helix domain
NMFKLGDN_00723 2.4e-71 L Reverse transcriptase (RNA-dependent DNA polymerase)
NMFKLGDN_00724 1.9e-46 L Transposase
NMFKLGDN_00725 3.4e-171 L Integrase core domain
NMFKLGDN_00726 8.9e-178 L Belongs to the 'phage' integrase family
NMFKLGDN_00727 5.3e-59 3.1.21.3 V Type I restriction modification DNA specificity domain
NMFKLGDN_00728 2.6e-38 higA K Helix-turn-helix XRE-family like proteins
NMFKLGDN_00729 1.4e-44 S RelE-like toxin of type II toxin-antitoxin system HigB
NMFKLGDN_00730 2.2e-53 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
NMFKLGDN_00731 3.4e-171 L Integrase core domain
NMFKLGDN_00732 1.9e-46 L Transposase
NMFKLGDN_00733 2e-48 L PFAM transposase IS200-family protein
NMFKLGDN_00734 7.4e-134 K LysR substrate binding domain
NMFKLGDN_00735 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NMFKLGDN_00736 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NMFKLGDN_00737 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMFKLGDN_00738 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NMFKLGDN_00739 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMFKLGDN_00740 5.1e-116 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NMFKLGDN_00741 1.3e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMFKLGDN_00742 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NMFKLGDN_00743 4.9e-177 K AI-2E family transporter
NMFKLGDN_00744 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NMFKLGDN_00745 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NMFKLGDN_00746 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NMFKLGDN_00747 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NMFKLGDN_00748 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NMFKLGDN_00749 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMFKLGDN_00750 9.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NMFKLGDN_00751 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMFKLGDN_00752 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMFKLGDN_00753 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMFKLGDN_00754 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NMFKLGDN_00755 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NMFKLGDN_00756 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMFKLGDN_00757 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NMFKLGDN_00758 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
NMFKLGDN_00759 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NMFKLGDN_00760 9.7e-173
NMFKLGDN_00761 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMFKLGDN_00762 2.7e-26 K TRANSCRIPTIONal
NMFKLGDN_00763 7.9e-61 pldB 3.1.1.5 I Serine aminopeptidase, S33
NMFKLGDN_00764 5.6e-79 pncA Q Isochorismatase family
NMFKLGDN_00765 4e-230 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMFKLGDN_00766 4.2e-111 3.6.1.13, 3.6.1.55 F NUDIX domain
NMFKLGDN_00767 6.7e-278 pipD E Dipeptidase
NMFKLGDN_00768 0.0 yjbQ P TrkA C-terminal domain protein
NMFKLGDN_00769 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NMFKLGDN_00770 4e-289 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NMFKLGDN_00771 1.4e-81
NMFKLGDN_00772 5.9e-114 L PFAM Integrase catalytic region
NMFKLGDN_00773 1.6e-52 azlD S branched-chain amino acid
NMFKLGDN_00774 3.7e-136 azlC E AzlC protein
NMFKLGDN_00775 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
NMFKLGDN_00776 1.2e-123 K response regulator
NMFKLGDN_00777 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NMFKLGDN_00778 9.5e-172 deoR K sugar-binding domain protein
NMFKLGDN_00779 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NMFKLGDN_00780 2.7e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NMFKLGDN_00781 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NMFKLGDN_00782 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMFKLGDN_00783 2.9e-134 XK27_01040 S Protein of unknown function (DUF1129)
NMFKLGDN_00784 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NMFKLGDN_00785 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
NMFKLGDN_00786 1.7e-154 spo0J K Belongs to the ParB family
NMFKLGDN_00787 3.9e-139 soj D Sporulation initiation inhibitor
NMFKLGDN_00788 3.3e-151 noc K Belongs to the ParB family
NMFKLGDN_00789 1.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NMFKLGDN_00790 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NMFKLGDN_00791 5.6e-169 rihC 3.2.2.1 F Nucleoside
NMFKLGDN_00792 2.3e-218 nupG F Nucleoside transporter
NMFKLGDN_00793 1.6e-220 cycA E Amino acid permease
NMFKLGDN_00795 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NMFKLGDN_00796 1.2e-264 glnP P ABC transporter
NMFKLGDN_00797 2.2e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMFKLGDN_00798 2.2e-75 L hmm pf00665
NMFKLGDN_00800 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NMFKLGDN_00801 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMFKLGDN_00802 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
NMFKLGDN_00803 4.7e-114 yjbH Q Thioredoxin
NMFKLGDN_00804 9.2e-264 pipD E Dipeptidase
NMFKLGDN_00805 3e-203 coiA 3.6.4.12 S Competence protein
NMFKLGDN_00806 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NMFKLGDN_00807 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NMFKLGDN_00808 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NMFKLGDN_00809 3.8e-60 S Uncharacterised protein family (UPF0236)
NMFKLGDN_00810 1e-37 M Peptidase_C39 like family
NMFKLGDN_00811 4e-112 S Psort location CytoplasmicMembrane, score
NMFKLGDN_00812 6.7e-37
NMFKLGDN_00813 8.8e-75 cps3I G Acyltransferase family
NMFKLGDN_00814 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NMFKLGDN_00815 1.4e-230 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NMFKLGDN_00816 2.5e-163 yueF S AI-2E family transporter
NMFKLGDN_00817 1.3e-20
NMFKLGDN_00818 2.7e-54 M repeat protein
NMFKLGDN_00819 2.6e-12 S integral membrane protein
NMFKLGDN_00820 3.4e-171 L Integrase core domain
NMFKLGDN_00821 1.9e-46 L Transposase
NMFKLGDN_00822 5.3e-259 ganB 3.2.1.89 G arabinogalactan
NMFKLGDN_00823 1.9e-46 L Transposase
NMFKLGDN_00824 3.4e-171 L Integrase core domain
NMFKLGDN_00825 5.7e-206
NMFKLGDN_00827 1.9e-74 S Transcriptional regulator, RinA family
NMFKLGDN_00832 2.6e-129 dck 2.7.1.74 F deoxynucleoside kinase
NMFKLGDN_00838 1.2e-140
NMFKLGDN_00844 4.1e-21
NMFKLGDN_00848 5.1e-70 rusA L Endodeoxyribonuclease RusA
NMFKLGDN_00849 4.1e-21
NMFKLGDN_00851 1.9e-46 L Transposase
NMFKLGDN_00852 3.4e-171 L Integrase core domain
NMFKLGDN_00853 1.9e-46 L Transposase
NMFKLGDN_00854 3.4e-171 L Integrase core domain
NMFKLGDN_00855 1.7e-38 E Zn peptidase
NMFKLGDN_00856 1.2e-36 K Helix-turn-helix XRE-family like proteins
NMFKLGDN_00858 3.5e-68 S DNA binding
NMFKLGDN_00860 1.4e-15 S Hypothetical protein (DUF2513)
NMFKLGDN_00861 1.8e-17
NMFKLGDN_00863 6.5e-33
NMFKLGDN_00867 1.7e-122 S AAA domain
NMFKLGDN_00868 1.8e-91 S Protein of unknown function (DUF669)
NMFKLGDN_00869 1.9e-69 ybl78 L DnaD domain protein
NMFKLGDN_00870 1.4e-57 dnaC 3.4.21.53 L IstB-like ATP binding protein
NMFKLGDN_00872 1.1e-52 S Protein of unknown function (DUF1064)
NMFKLGDN_00876 2e-76
NMFKLGDN_00881 3.1e-65 K Domain of unknown function (DUF4417)
NMFKLGDN_00883 4.7e-62 ps333 L Terminase small subunit
NMFKLGDN_00884 2.1e-187 ps334 S Terminase-like family
NMFKLGDN_00885 3.1e-145 S Phage portal protein
NMFKLGDN_00886 8.9e-86 S Phage Mu protein F like protein
NMFKLGDN_00889 1.3e-42 S Domain of unknown function (DUF4355)
NMFKLGDN_00890 1e-118
NMFKLGDN_00891 8.9e-31 S Phage gp6-like head-tail connector protein
NMFKLGDN_00892 3.3e-36
NMFKLGDN_00893 2.4e-30 S Bacteriophage HK97-gp10, putative tail-component
NMFKLGDN_00894 2.5e-28 S Protein of unknown function (DUF3168)
NMFKLGDN_00895 7.6e-43 S Phage tail tube protein
NMFKLGDN_00896 1e-22 S Phage tail assembly chaperone protein, TAC
NMFKLGDN_00897 1.8e-13
NMFKLGDN_00898 1.8e-142 Z012_10445 D Phage tail tape measure protein
NMFKLGDN_00899 3.7e-91 S Phage tail protein
NMFKLGDN_00900 1.7e-212 M CHAP domain
NMFKLGDN_00903 2.4e-41 S Calcineurin-like phosphoesterase
NMFKLGDN_00904 2e-14 N Bacterial Ig-like domain 2
NMFKLGDN_00906 1.8e-22 S dextransucrase activity
NMFKLGDN_00909 1.3e-34
NMFKLGDN_00910 2.9e-30 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NMFKLGDN_00911 1.9e-190 ps461 3.5.1.104 M hydrolase, family 25
NMFKLGDN_00912 2.9e-34
NMFKLGDN_00913 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
NMFKLGDN_00914 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
NMFKLGDN_00915 3.3e-83
NMFKLGDN_00916 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NMFKLGDN_00917 2.4e-105 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NMFKLGDN_00918 3.4e-171 L Integrase core domain
NMFKLGDN_00919 1.9e-46 L Transposase
NMFKLGDN_00923 1e-38
NMFKLGDN_00924 1e-48
NMFKLGDN_00925 4.5e-208 L Belongs to the 'phage' integrase family
NMFKLGDN_00926 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NMFKLGDN_00927 9.9e-261 yfnA E amino acid
NMFKLGDN_00928 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NMFKLGDN_00929 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMFKLGDN_00930 1.3e-38 ylqC S Belongs to the UPF0109 family
NMFKLGDN_00931 6.5e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NMFKLGDN_00932 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMFKLGDN_00933 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMFKLGDN_00934 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NMFKLGDN_00935 0.0 smc D Required for chromosome condensation and partitioning
NMFKLGDN_00936 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NMFKLGDN_00937 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMFKLGDN_00938 6.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NMFKLGDN_00939 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMFKLGDN_00940 7.1e-311 yloV S DAK2 domain fusion protein YloV
NMFKLGDN_00941 4.7e-58 asp S Asp23 family, cell envelope-related function
NMFKLGDN_00942 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NMFKLGDN_00943 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NMFKLGDN_00944 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NMFKLGDN_00945 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NMFKLGDN_00946 0.0 KLT serine threonine protein kinase
NMFKLGDN_00947 2.9e-131 stp 3.1.3.16 T phosphatase
NMFKLGDN_00948 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMFKLGDN_00949 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMFKLGDN_00950 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMFKLGDN_00951 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMFKLGDN_00952 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NMFKLGDN_00953 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NMFKLGDN_00954 1.7e-54
NMFKLGDN_00955 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
NMFKLGDN_00956 8.1e-76 argR K Regulates arginine biosynthesis genes
NMFKLGDN_00957 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NMFKLGDN_00958 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMFKLGDN_00959 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMFKLGDN_00960 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMFKLGDN_00961 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMFKLGDN_00962 3.6e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMFKLGDN_00963 2.2e-70 yqhY S Asp23 family, cell envelope-related function
NMFKLGDN_00964 1.7e-114 J 2'-5' RNA ligase superfamily
NMFKLGDN_00965 7.8e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NMFKLGDN_00966 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMFKLGDN_00967 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NMFKLGDN_00968 1.6e-54 ysxB J Cysteine protease Prp
NMFKLGDN_00969 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NMFKLGDN_00970 5.8e-112 K Transcriptional regulator
NMFKLGDN_00973 1.4e-84 dut S Protein conserved in bacteria
NMFKLGDN_00974 2.3e-174
NMFKLGDN_00975 3.4e-150
NMFKLGDN_00976 3.1e-50 S Iron-sulfur cluster assembly protein
NMFKLGDN_00977 1.6e-123 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NMFKLGDN_00978 3.9e-87 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NMFKLGDN_00979 2.4e-131 pfoR S COG1299 Phosphotransferase system, fructose-specific IIC component
NMFKLGDN_00980 8.3e-43 S YheO-like PAS domain
NMFKLGDN_00982 6.3e-102 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMFKLGDN_00983 4.1e-189 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMFKLGDN_00984 5.6e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMFKLGDN_00985 1.6e-154 P Belongs to the nlpA lipoprotein family
NMFKLGDN_00986 3.9e-12
NMFKLGDN_00987 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NMFKLGDN_00988 1.7e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMFKLGDN_00989 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
NMFKLGDN_00990 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMFKLGDN_00991 5.9e-22 S Protein of unknown function (DUF3042)
NMFKLGDN_00992 3.4e-67 yqhL P Rhodanese-like protein
NMFKLGDN_00993 5.6e-183 glk 2.7.1.2 G Glucokinase
NMFKLGDN_00994 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NMFKLGDN_00995 3.8e-46 gluP 3.4.21.105 S Peptidase, S54 family
NMFKLGDN_00996 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
NMFKLGDN_00997 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMFKLGDN_00998 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMFKLGDN_00999 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NMFKLGDN_01000 0.0 S membrane
NMFKLGDN_01001 8.8e-71 yneR S Belongs to the HesB IscA family
NMFKLGDN_01002 2e-48 L PFAM transposase IS200-family protein
NMFKLGDN_01003 2.1e-42 O Bacterial dnaA protein
NMFKLGDN_01004 4e-73 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NMFKLGDN_01005 2.1e-42 O Bacterial dnaA protein
NMFKLGDN_01006 9.8e-09 K DNA-binding helix-turn-helix protein
NMFKLGDN_01007 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NMFKLGDN_01008 3.7e-54
NMFKLGDN_01009 9.9e-206 yttB EGP Major facilitator Superfamily
NMFKLGDN_01010 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NMFKLGDN_01011 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMFKLGDN_01012 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NMFKLGDN_01013 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NMFKLGDN_01014 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMFKLGDN_01015 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMFKLGDN_01016 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMFKLGDN_01017 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMFKLGDN_01018 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMFKLGDN_01019 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
NMFKLGDN_01020 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMFKLGDN_01021 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMFKLGDN_01022 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMFKLGDN_01023 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMFKLGDN_01024 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMFKLGDN_01025 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMFKLGDN_01026 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMFKLGDN_01027 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMFKLGDN_01028 2.9e-24 rpmD J Ribosomal protein L30
NMFKLGDN_01029 8.9e-64 rplO J Binds to the 23S rRNA
NMFKLGDN_01030 2e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NMFKLGDN_01031 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NMFKLGDN_01032 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMFKLGDN_01033 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NMFKLGDN_01034 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMFKLGDN_01035 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMFKLGDN_01036 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMFKLGDN_01037 1.1e-62 rplQ J Ribosomal protein L17
NMFKLGDN_01038 8.8e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMFKLGDN_01039 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMFKLGDN_01040 2.2e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMFKLGDN_01041 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NMFKLGDN_01042 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMFKLGDN_01043 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NMFKLGDN_01044 3.6e-140 IQ reductase
NMFKLGDN_01045 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
NMFKLGDN_01046 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NMFKLGDN_01047 1.1e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NMFKLGDN_01048 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NMFKLGDN_01049 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMFKLGDN_01050 2.1e-202 camS S sex pheromone
NMFKLGDN_01051 2e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMFKLGDN_01052 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NMFKLGDN_01053 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMFKLGDN_01054 5.6e-186 yegS 2.7.1.107 G Lipid kinase
NMFKLGDN_01055 2.7e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMFKLGDN_01056 9.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NMFKLGDN_01057 0.0 L Helicase C-terminal domain protein
NMFKLGDN_01058 1.4e-20
NMFKLGDN_01059 7.6e-88 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NMFKLGDN_01060 2.6e-195 M transferase activity, transferring glycosyl groups
NMFKLGDN_01061 3.1e-217 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
NMFKLGDN_01062 2.1e-106 asp3 S Accessory Sec secretory system ASP3
NMFKLGDN_01063 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMFKLGDN_01064 1.1e-225 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NMFKLGDN_01065 7.9e-196 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NMFKLGDN_01067 3.6e-17 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
NMFKLGDN_01068 7e-08 UW Hep Hag repeat protein
NMFKLGDN_01069 2.1e-42 O Bacterial dnaA protein
NMFKLGDN_01070 3.7e-123
NMFKLGDN_01071 2.2e-243 ydaM M Glycosyl transferase
NMFKLGDN_01072 4.8e-218 G Glycosyl hydrolases family 8
NMFKLGDN_01073 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NMFKLGDN_01074 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NMFKLGDN_01075 1.7e-238 ktrB P Potassium uptake protein
NMFKLGDN_01076 1.4e-116 ktrA P domain protein
NMFKLGDN_01077 2.7e-81 Q Methyltransferase
NMFKLGDN_01078 7.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
NMFKLGDN_01079 5.7e-82 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NMFKLGDN_01080 3.4e-68 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NMFKLGDN_01081 6.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMFKLGDN_01082 1.4e-18 S NADPH-dependent FMN reductase
NMFKLGDN_01083 5.9e-67 S NADPH-dependent FMN reductase
NMFKLGDN_01084 5.8e-216 G Belongs to the glycosyl hydrolase family 6
NMFKLGDN_01085 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
NMFKLGDN_01086 3.5e-134 I alpha/beta hydrolase fold
NMFKLGDN_01087 2e-168 lsa S ABC transporter
NMFKLGDN_01088 8.6e-59 lsa S ABC transporter
NMFKLGDN_01089 2.5e-59 S Uncharacterised protein family (UPF0236)
NMFKLGDN_01097 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
NMFKLGDN_01098 1.5e-237 lmrB EGP Major facilitator Superfamily
NMFKLGDN_01099 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NMFKLGDN_01100 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NMFKLGDN_01101 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
NMFKLGDN_01102 2.6e-80 lytE M LysM domain protein
NMFKLGDN_01103 0.0 oppD EP Psort location Cytoplasmic, score
NMFKLGDN_01104 2.3e-93 lytE M LysM domain protein
NMFKLGDN_01105 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
NMFKLGDN_01106 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NMFKLGDN_01107 2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
NMFKLGDN_01108 8.1e-154 yeaE S Aldo keto
NMFKLGDN_01109 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
NMFKLGDN_01110 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NMFKLGDN_01111 2.9e-78 S Psort location Cytoplasmic, score
NMFKLGDN_01112 7.7e-86 S Short repeat of unknown function (DUF308)
NMFKLGDN_01113 1e-23
NMFKLGDN_01114 2.8e-102 V VanZ like family
NMFKLGDN_01115 4.8e-233 cycA E Amino acid permease
NMFKLGDN_01116 4.3e-85 perR P Belongs to the Fur family
NMFKLGDN_01117 1.5e-253 EGP Major facilitator Superfamily
NMFKLGDN_01118 9.6e-92 tag 3.2.2.20 L glycosylase
NMFKLGDN_01119 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMFKLGDN_01120 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMFKLGDN_01121 4.9e-41
NMFKLGDN_01122 4.1e-303 ytgP S Polysaccharide biosynthesis protein
NMFKLGDN_01123 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMFKLGDN_01124 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
NMFKLGDN_01125 1.2e-85 uspA T Belongs to the universal stress protein A family
NMFKLGDN_01126 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMFKLGDN_01127 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
NMFKLGDN_01128 3.8e-113
NMFKLGDN_01129 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NMFKLGDN_01130 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMFKLGDN_01131 2.1e-32
NMFKLGDN_01132 2.9e-111 S CAAX protease self-immunity
NMFKLGDN_01133 1.9e-43
NMFKLGDN_01135 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMFKLGDN_01136 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NMFKLGDN_01137 1.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NMFKLGDN_01138 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NMFKLGDN_01139 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NMFKLGDN_01140 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
NMFKLGDN_01141 1.8e-43
NMFKLGDN_01142 3.3e-40
NMFKLGDN_01144 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMFKLGDN_01145 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMFKLGDN_01146 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NMFKLGDN_01147 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMFKLGDN_01148 3.5e-40 yheA S Belongs to the UPF0342 family
NMFKLGDN_01149 1.8e-220 yhaO L Ser Thr phosphatase family protein
NMFKLGDN_01150 0.0 L AAA domain
NMFKLGDN_01151 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NMFKLGDN_01153 1.2e-76 hit FG histidine triad
NMFKLGDN_01154 3.9e-136 ecsA V ABC transporter, ATP-binding protein
NMFKLGDN_01155 5.1e-218 ecsB U ABC transporter
NMFKLGDN_01156 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NMFKLGDN_01157 7.7e-27 S YSIRK type signal peptide
NMFKLGDN_01158 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
NMFKLGDN_01159 9.5e-256 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
NMFKLGDN_01160 3.3e-144 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NMFKLGDN_01161 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NMFKLGDN_01162 8.8e-184 iolS C Aldo keto reductase
NMFKLGDN_01163 9.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
NMFKLGDN_01164 7.5e-58 ytzB S Small secreted protein
NMFKLGDN_01165 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMFKLGDN_01166 7.2e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMFKLGDN_01167 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
NMFKLGDN_01168 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NMFKLGDN_01169 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NMFKLGDN_01170 1.9e-119 ybhL S Belongs to the BI1 family
NMFKLGDN_01171 2e-115 yoaK S Protein of unknown function (DUF1275)
NMFKLGDN_01172 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMFKLGDN_01173 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NMFKLGDN_01174 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMFKLGDN_01175 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMFKLGDN_01176 1.4e-203 dnaB L replication initiation and membrane attachment
NMFKLGDN_01177 1.1e-170 dnaI L Primosomal protein DnaI
NMFKLGDN_01178 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMFKLGDN_01179 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NMFKLGDN_01180 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMFKLGDN_01181 1.8e-95 yqeG S HAD phosphatase, family IIIA
NMFKLGDN_01182 4.8e-218 yqeH S Ribosome biogenesis GTPase YqeH
NMFKLGDN_01183 1.9e-47 yhbY J RNA-binding protein
NMFKLGDN_01184 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMFKLGDN_01185 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NMFKLGDN_01186 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NMFKLGDN_01187 4.5e-140 yqeM Q Methyltransferase
NMFKLGDN_01188 2.1e-213 ylbM S Belongs to the UPF0348 family
NMFKLGDN_01189 2.9e-99 yceD S Uncharacterized ACR, COG1399
NMFKLGDN_01190 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NMFKLGDN_01191 1.5e-121 K response regulator
NMFKLGDN_01192 2.7e-277 arlS 2.7.13.3 T Histidine kinase
NMFKLGDN_01193 7.4e-267 yjeM E Amino Acid
NMFKLGDN_01194 4.4e-231 V MatE
NMFKLGDN_01195 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NMFKLGDN_01196 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMFKLGDN_01197 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NMFKLGDN_01198 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMFKLGDN_01199 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NMFKLGDN_01200 2e-58 yodB K Transcriptional regulator, HxlR family
NMFKLGDN_01201 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMFKLGDN_01202 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMFKLGDN_01203 5.6e-115 rlpA M PFAM NLP P60 protein
NMFKLGDN_01204 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
NMFKLGDN_01205 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMFKLGDN_01217 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NMFKLGDN_01218 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NMFKLGDN_01219 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
NMFKLGDN_01220 2e-92 folT S ECF transporter, substrate-specific component
NMFKLGDN_01221 0.0 pepN 3.4.11.2 E aminopeptidase
NMFKLGDN_01222 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
NMFKLGDN_01223 9.8e-255 pepC 3.4.22.40 E aminopeptidase
NMFKLGDN_01224 6.5e-210 EGP Major facilitator Superfamily
NMFKLGDN_01225 1.8e-229
NMFKLGDN_01226 3.5e-79 K Transcriptional regulator, HxlR family
NMFKLGDN_01227 3.7e-108 XK27_02070 S Nitroreductase family
NMFKLGDN_01228 6.2e-51 hxlR K Transcriptional regulator, HxlR family
NMFKLGDN_01229 3e-119 GM NmrA-like family
NMFKLGDN_01230 1.7e-70 elaA S Gnat family
NMFKLGDN_01231 1.8e-39 S Cytochrome B5
NMFKLGDN_01232 5.4e-09 S Cytochrome B5
NMFKLGDN_01233 7.8e-41 S Cytochrome B5
NMFKLGDN_01234 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
NMFKLGDN_01236 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMFKLGDN_01237 1.1e-240 E amino acid
NMFKLGDN_01238 2.8e-215 npp S type I phosphodiesterase nucleotide pyrophosphatase
NMFKLGDN_01239 3.1e-226 yxiO S Vacuole effluxer Atg22 like
NMFKLGDN_01241 5.8e-64
NMFKLGDN_01242 9e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NMFKLGDN_01243 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMFKLGDN_01244 0.0 dnaK O Heat shock 70 kDa protein
NMFKLGDN_01245 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NMFKLGDN_01246 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NMFKLGDN_01247 4.1e-275 pipD E Dipeptidase
NMFKLGDN_01248 4.7e-199 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NMFKLGDN_01250 2.6e-80 comEA L Competence protein ComEA
NMFKLGDN_01251 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
NMFKLGDN_01252 0.0 comEC S Competence protein ComEC
NMFKLGDN_01253 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
NMFKLGDN_01254 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
NMFKLGDN_01255 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMFKLGDN_01256 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMFKLGDN_01257 7.8e-163 S Tetratricopeptide repeat
NMFKLGDN_01258 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMFKLGDN_01259 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NMFKLGDN_01260 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMFKLGDN_01261 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
NMFKLGDN_01262 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NMFKLGDN_01263 1.3e-08
NMFKLGDN_01264 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NMFKLGDN_01265 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMFKLGDN_01266 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NMFKLGDN_01267 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFKLGDN_01268 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NMFKLGDN_01269 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMFKLGDN_01270 2.1e-87
NMFKLGDN_01271 4.3e-208 potD P ABC transporter
NMFKLGDN_01272 4.9e-140 potC P ABC transporter permease
NMFKLGDN_01273 1.7e-145 potB P ABC transporter permease
NMFKLGDN_01274 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NMFKLGDN_01275 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NMFKLGDN_01276 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NMFKLGDN_01277 0.0 pacL 3.6.3.8 P P-type ATPase
NMFKLGDN_01278 3.4e-85 dps P Belongs to the Dps family
NMFKLGDN_01279 2.8e-255 yagE E amino acid
NMFKLGDN_01280 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NMFKLGDN_01281 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NMFKLGDN_01282 2.5e-127 L Helix-turn-helix domain
NMFKLGDN_01283 6.7e-150 L hmm pf00665
NMFKLGDN_01284 8.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NMFKLGDN_01285 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
NMFKLGDN_01286 2.5e-138 IQ KR domain
NMFKLGDN_01287 3.3e-133 S membrane transporter protein
NMFKLGDN_01288 3e-96 S ABC-type cobalt transport system, permease component
NMFKLGDN_01289 1.6e-247 cbiO1 S ABC transporter, ATP-binding protein
NMFKLGDN_01290 9.2e-113 P Cobalt transport protein
NMFKLGDN_01291 1.6e-52 yvlA
NMFKLGDN_01292 0.0 yjcE P Sodium proton antiporter
NMFKLGDN_01293 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NMFKLGDN_01294 2.2e-52 ypaA S Protein of unknown function (DUF1304)
NMFKLGDN_01295 3.7e-190 D Alpha beta
NMFKLGDN_01296 1e-72 K Transcriptional regulator
NMFKLGDN_01297 1.1e-161
NMFKLGDN_01298 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
NMFKLGDN_01299 1.3e-257 G PTS system Galactitol-specific IIC component
NMFKLGDN_01300 1.4e-212 EGP Major facilitator Superfamily
NMFKLGDN_01301 3.4e-13
NMFKLGDN_01302 7.1e-63
NMFKLGDN_01303 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
NMFKLGDN_01304 5.1e-81 uspA T universal stress protein
NMFKLGDN_01305 0.0 tetP J elongation factor G
NMFKLGDN_01306 2e-166 GK ROK family
NMFKLGDN_01307 1.1e-240 brnQ U Component of the transport system for branched-chain amino acids
NMFKLGDN_01308 4.5e-140 aroD S Serine hydrolase (FSH1)
NMFKLGDN_01309 2.7e-244 yagE E amino acid
NMFKLGDN_01310 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NMFKLGDN_01311 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
NMFKLGDN_01312 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMFKLGDN_01313 1.1e-283 pipD E Dipeptidase
NMFKLGDN_01314 0.0 yfiC V ABC transporter
NMFKLGDN_01315 1.1e-309 lmrA V ABC transporter, ATP-binding protein
NMFKLGDN_01316 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMFKLGDN_01317 2.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NMFKLGDN_01318 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NMFKLGDN_01319 5.5e-40 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NMFKLGDN_01320 8.4e-156 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NMFKLGDN_01321 3.2e-264 argH 4.3.2.1 E argininosuccinate lyase
NMFKLGDN_01322 1.1e-90 bioY S BioY family
NMFKLGDN_01323 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NMFKLGDN_01324 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
NMFKLGDN_01325 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMFKLGDN_01326 9.9e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NMFKLGDN_01327 7.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMFKLGDN_01328 1.5e-146 recO L Involved in DNA repair and RecF pathway recombination
NMFKLGDN_01329 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NMFKLGDN_01330 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NMFKLGDN_01331 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NMFKLGDN_01332 1.9e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NMFKLGDN_01333 1.2e-219 patA 2.6.1.1 E Aminotransferase
NMFKLGDN_01334 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
NMFKLGDN_01335 1.2e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMFKLGDN_01336 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NMFKLGDN_01337 3e-30 S Protein of unknown function (DUF2929)
NMFKLGDN_01338 0.0 dnaE 2.7.7.7 L DNA polymerase
NMFKLGDN_01339 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NMFKLGDN_01340 2.3e-167 cvfB S S1 domain
NMFKLGDN_01341 1.2e-163 xerD D recombinase XerD
NMFKLGDN_01342 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMFKLGDN_01343 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMFKLGDN_01344 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMFKLGDN_01345 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMFKLGDN_01346 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMFKLGDN_01347 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
NMFKLGDN_01348 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NMFKLGDN_01349 8.5e-14 M Lysin motif
NMFKLGDN_01350 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NMFKLGDN_01351 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NMFKLGDN_01352 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NMFKLGDN_01353 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMFKLGDN_01354 1.5e-236 S Tetratricopeptide repeat protein
NMFKLGDN_01355 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NMFKLGDN_01356 0.0 yfmR S ABC transporter, ATP-binding protein
NMFKLGDN_01357 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMFKLGDN_01358 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMFKLGDN_01359 5.3e-113 hlyIII S protein, hemolysin III
NMFKLGDN_01360 1.7e-151 DegV S EDD domain protein, DegV family
NMFKLGDN_01361 9.5e-172 ypmR E lipolytic protein G-D-S-L family
NMFKLGDN_01362 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NMFKLGDN_01363 4.4e-35 yozE S Belongs to the UPF0346 family
NMFKLGDN_01364 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMFKLGDN_01365 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMFKLGDN_01366 2.4e-161 dprA LU DNA protecting protein DprA
NMFKLGDN_01367 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMFKLGDN_01368 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
NMFKLGDN_01369 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMFKLGDN_01370 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMFKLGDN_01371 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMFKLGDN_01372 1.7e-84 F NUDIX domain
NMFKLGDN_01373 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
NMFKLGDN_01374 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMFKLGDN_01375 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
NMFKLGDN_01376 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMFKLGDN_01377 7.4e-141 ymfM S Helix-turn-helix domain
NMFKLGDN_01378 3.2e-250 ymfH S Peptidase M16
NMFKLGDN_01379 1.6e-230 ymfF S Peptidase M16 inactive domain protein
NMFKLGDN_01380 2.6e-160 aatB ET ABC transporter substrate-binding protein
NMFKLGDN_01381 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NMFKLGDN_01382 3.2e-102 glnP P ABC transporter permease
NMFKLGDN_01383 1.2e-91 mreD M rod shape-determining protein MreD
NMFKLGDN_01384 2.2e-151 mreC M Involved in formation and maintenance of cell shape
NMFKLGDN_01385 1.7e-179 mreB D cell shape determining protein MreB
NMFKLGDN_01386 6.8e-121 radC L DNA repair protein
NMFKLGDN_01387 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NMFKLGDN_01388 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
NMFKLGDN_01389 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NMFKLGDN_01390 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NMFKLGDN_01391 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NMFKLGDN_01392 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
NMFKLGDN_01393 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NMFKLGDN_01394 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMFKLGDN_01395 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
NMFKLGDN_01396 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMFKLGDN_01397 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMFKLGDN_01398 1.3e-262 L Transposase
NMFKLGDN_01399 3.1e-235 pbuG S permease
NMFKLGDN_01400 4.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NMFKLGDN_01401 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NMFKLGDN_01402 2.5e-135 S Belongs to the UPF0246 family
NMFKLGDN_01403 2.5e-138 S Membrane
NMFKLGDN_01404 8.1e-75 4.4.1.5 E Glyoxalase
NMFKLGDN_01405 1.5e-21
NMFKLGDN_01406 7.1e-86 yueI S Protein of unknown function (DUF1694)
NMFKLGDN_01407 1.1e-234 rarA L recombination factor protein RarA
NMFKLGDN_01408 4.4e-46
NMFKLGDN_01409 4.3e-83 usp6 T universal stress protein
NMFKLGDN_01410 2.8e-207 araR K Transcriptional regulator
NMFKLGDN_01411 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
NMFKLGDN_01412 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
NMFKLGDN_01413 1.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NMFKLGDN_01414 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NMFKLGDN_01415 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
NMFKLGDN_01416 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NMFKLGDN_01418 5.2e-56
NMFKLGDN_01420 4.5e-85
NMFKLGDN_01421 0.0 copA 3.6.3.54 P P-type ATPase
NMFKLGDN_01422 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NMFKLGDN_01423 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NMFKLGDN_01424 5.9e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NMFKLGDN_01425 1.2e-160 EG EamA-like transporter family
NMFKLGDN_01426 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NMFKLGDN_01427 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMFKLGDN_01428 8.1e-154 KT YcbB domain
NMFKLGDN_01429 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
NMFKLGDN_01430 2e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NMFKLGDN_01431 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
NMFKLGDN_01432 3.4e-132 O Bacterial dnaA protein
NMFKLGDN_01433 3.2e-236 L Integrase core domain
NMFKLGDN_01435 5.9e-191 V Beta-lactamase
NMFKLGDN_01436 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NMFKLGDN_01437 5e-122 yhiD S MgtC family
NMFKLGDN_01438 6.4e-39 S GyrI-like small molecule binding domain
NMFKLGDN_01439 2.7e-70 S GyrI-like small molecule binding domain
NMFKLGDN_01441 5.5e-118 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NMFKLGDN_01442 7.1e-50 azlD E Branched-chain amino acid transport
NMFKLGDN_01443 1.4e-119 azlC E azaleucine resistance protein AzlC
NMFKLGDN_01444 7.3e-60 K Aminotransferase class I and II
NMFKLGDN_01445 1.6e-163 K Aminotransferase class I and II
NMFKLGDN_01446 3.6e-288 S amidohydrolase
NMFKLGDN_01448 1.8e-161 S reductase
NMFKLGDN_01449 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
NMFKLGDN_01450 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NMFKLGDN_01451 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
NMFKLGDN_01452 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMFKLGDN_01453 0.0 asnB 6.3.5.4 E Asparagine synthase
NMFKLGDN_01454 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NMFKLGDN_01455 8.7e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMFKLGDN_01456 9.7e-130 jag S R3H domain protein
NMFKLGDN_01457 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMFKLGDN_01458 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NMFKLGDN_01459 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NMFKLGDN_01460 6.5e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMFKLGDN_01461 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NMFKLGDN_01462 1.6e-81 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NMFKLGDN_01463 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NMFKLGDN_01464 1.7e-34 yaaA S S4 domain protein YaaA
NMFKLGDN_01465 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMFKLGDN_01466 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMFKLGDN_01467 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMFKLGDN_01468 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NMFKLGDN_01469 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMFKLGDN_01470 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMFKLGDN_01471 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NMFKLGDN_01472 2e-74 rplI J Binds to the 23S rRNA
NMFKLGDN_01473 1.6e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NMFKLGDN_01474 2e-192 L Integrase core domain
NMFKLGDN_01475 8.2e-126 O Bacterial dnaA protein
NMFKLGDN_01476 3.2e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NMFKLGDN_01479 5.5e-280 O Arylsulfotransferase (ASST)
NMFKLGDN_01480 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NMFKLGDN_01481 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMFKLGDN_01482 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMFKLGDN_01483 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMFKLGDN_01484 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NMFKLGDN_01485 4.6e-255 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NMFKLGDN_01486 9.8e-67 yabR J RNA binding
NMFKLGDN_01487 3.3e-56 divIC D Septum formation initiator
NMFKLGDN_01488 8.1e-39 yabO J S4 domain protein
NMFKLGDN_01489 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMFKLGDN_01490 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NMFKLGDN_01491 4e-113 S (CBS) domain
NMFKLGDN_01492 3.1e-147 tesE Q hydratase
NMFKLGDN_01493 4.7e-243 codA 3.5.4.1 F cytosine deaminase
NMFKLGDN_01494 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
NMFKLGDN_01495 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
NMFKLGDN_01496 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMFKLGDN_01497 1.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NMFKLGDN_01499 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMFKLGDN_01500 2.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
NMFKLGDN_01501 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMFKLGDN_01502 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMFKLGDN_01503 6.5e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
NMFKLGDN_01504 3.7e-136 sprD D Domain of Unknown Function (DUF1542)
NMFKLGDN_01505 3.1e-126 L PFAM Integrase catalytic region
NMFKLGDN_01506 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NMFKLGDN_01507 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NMFKLGDN_01508 2.6e-158 htpX O Belongs to the peptidase M48B family
NMFKLGDN_01509 7e-93 lemA S LemA family
NMFKLGDN_01510 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMFKLGDN_01511 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
NMFKLGDN_01512 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NMFKLGDN_01513 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMFKLGDN_01514 2.5e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NMFKLGDN_01515 1.1e-124 srtA 3.4.22.70 M sortase family
NMFKLGDN_01516 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
NMFKLGDN_01517 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMFKLGDN_01518 4.6e-41 rpmE2 J Ribosomal protein L31
NMFKLGDN_01519 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMFKLGDN_01520 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NMFKLGDN_01521 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NMFKLGDN_01522 3e-66 ywiB S Domain of unknown function (DUF1934)
NMFKLGDN_01523 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NMFKLGDN_01524 5e-270 ywfO S HD domain protein
NMFKLGDN_01525 2.5e-147 yxeH S hydrolase
NMFKLGDN_01526 2.1e-49
NMFKLGDN_01527 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMFKLGDN_01528 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMFKLGDN_01529 2.6e-149 purR 2.4.2.7 F pur operon repressor
NMFKLGDN_01530 1.4e-118 znuB U ABC 3 transport family
NMFKLGDN_01531 1.4e-121 fhuC P ABC transporter
NMFKLGDN_01532 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
NMFKLGDN_01533 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NMFKLGDN_01534 6.8e-37 veg S Biofilm formation stimulator VEG
NMFKLGDN_01535 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMFKLGDN_01536 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMFKLGDN_01537 1.9e-155 tatD L hydrolase, TatD family
NMFKLGDN_01538 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMFKLGDN_01539 3.6e-162 yunF F Protein of unknown function DUF72
NMFKLGDN_01541 1e-130 cobB K SIR2 family
NMFKLGDN_01542 1.6e-177
NMFKLGDN_01543 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NMFKLGDN_01544 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NMFKLGDN_01545 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMFKLGDN_01546 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NMFKLGDN_01547 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
NMFKLGDN_01548 0.0 helD 3.6.4.12 L DNA helicase
NMFKLGDN_01549 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NMFKLGDN_01551 3.8e-60 S Uncharacterised protein family (UPF0236)
NMFKLGDN_01552 7.2e-192 L Transposase
NMFKLGDN_01553 4.6e-24
NMFKLGDN_01554 1e-73
NMFKLGDN_01555 1.3e-260 S Putative peptidoglycan binding domain
NMFKLGDN_01557 7.2e-79 2.7.13.3 T GHKL domain
NMFKLGDN_01558 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NMFKLGDN_01559 1.2e-135 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NMFKLGDN_01560 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NMFKLGDN_01561 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NMFKLGDN_01562 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NMFKLGDN_01563 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NMFKLGDN_01564 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMFKLGDN_01565 4.2e-130 IQ reductase
NMFKLGDN_01566 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NMFKLGDN_01567 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMFKLGDN_01568 3.8e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMFKLGDN_01569 4.2e-77 marR K Transcriptional regulator, MarR family
NMFKLGDN_01570 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NMFKLGDN_01572 9.6e-200 xerS L Belongs to the 'phage' integrase family
NMFKLGDN_01573 8.7e-238 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NMFKLGDN_01574 1.4e-158 rssA S Phospholipase, patatin family
NMFKLGDN_01575 2.5e-118 L Integrase
NMFKLGDN_01576 1.2e-152 EG EamA-like transporter family
NMFKLGDN_01577 2e-180 yfeX P Peroxidase
NMFKLGDN_01578 2.2e-274 arcD S C4-dicarboxylate anaerobic carrier
NMFKLGDN_01579 9.8e-255 ytjP 3.5.1.18 E Dipeptidase
NMFKLGDN_01580 3.5e-214 uhpT EGP Major facilitator Superfamily
NMFKLGDN_01581 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NMFKLGDN_01582 4.8e-132 ponA V Beta-lactamase enzyme family
NMFKLGDN_01583 1.1e-113 frnE Q DSBA-like thioredoxin domain
NMFKLGDN_01584 2e-53
NMFKLGDN_01585 9.9e-149 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NMFKLGDN_01586 2.8e-170 S AI-2E family transporter
NMFKLGDN_01587 3.5e-154 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NMFKLGDN_01588 2.3e-162
NMFKLGDN_01589 5e-75 osmC O OsmC-like protein
NMFKLGDN_01590 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMFKLGDN_01591 1.8e-215 patA 2.6.1.1 E Aminotransferase
NMFKLGDN_01592 7.8e-32
NMFKLGDN_01593 0.0 clpL O associated with various cellular activities
NMFKLGDN_01595 9.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
NMFKLGDN_01596 6.1e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMFKLGDN_01597 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NMFKLGDN_01598 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NMFKLGDN_01599 1.5e-172 malR K Transcriptional regulator, LacI family
NMFKLGDN_01600 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
NMFKLGDN_01601 1.1e-256 malT G Major Facilitator
NMFKLGDN_01602 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NMFKLGDN_01603 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NMFKLGDN_01604 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
NMFKLGDN_01605 3.3e-118 K response regulator
NMFKLGDN_01606 5.3e-226 sptS 2.7.13.3 T Histidine kinase
NMFKLGDN_01607 2.5e-209 yfeO P Voltage gated chloride channel
NMFKLGDN_01608 8.1e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NMFKLGDN_01609 6.6e-136 puuD S peptidase C26
NMFKLGDN_01610 3.8e-167 yvgN C Aldo keto reductase
NMFKLGDN_01611 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
NMFKLGDN_01612 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NMFKLGDN_01613 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
NMFKLGDN_01614 4.2e-261 nox C NADH oxidase
NMFKLGDN_01615 7.3e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NMFKLGDN_01616 2.6e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMFKLGDN_01617 3e-86
NMFKLGDN_01618 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMFKLGDN_01620 4.3e-13 K Transcriptional regulator, TetR family
NMFKLGDN_01621 6.2e-76 K Transcriptional regulator, TetR family
NMFKLGDN_01622 2.2e-72
NMFKLGDN_01623 4.8e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NMFKLGDN_01624 7.9e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NMFKLGDN_01625 2.4e-277 M domain protein
NMFKLGDN_01626 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NMFKLGDN_01627 3.8e-188 G Major Facilitator
NMFKLGDN_01628 4.5e-49 G Major Facilitator
NMFKLGDN_01629 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NMFKLGDN_01630 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMFKLGDN_01631 1e-259 G Major Facilitator
NMFKLGDN_01632 2.4e-181 K Transcriptional regulator, LacI family
NMFKLGDN_01633 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMFKLGDN_01635 1.2e-100 nqr 1.5.1.36 S reductase
NMFKLGDN_01636 6.1e-198 XK27_09615 S reductase
NMFKLGDN_01637 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NMFKLGDN_01638 1.7e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NMFKLGDN_01639 3e-50 S CRISPR-associated protein (Cas_Csn2)
NMFKLGDN_01640 1.7e-185 lacR K Transcriptional regulator
NMFKLGDN_01641 2.1e-107 lacS G Transporter
NMFKLGDN_01642 6.5e-221 lacS G Transporter
NMFKLGDN_01643 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NMFKLGDN_01644 5.1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMFKLGDN_01645 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NMFKLGDN_01646 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NMFKLGDN_01647 1.2e-222 mdtG EGP Major facilitator Superfamily
NMFKLGDN_01648 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
NMFKLGDN_01649 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMFKLGDN_01651 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NMFKLGDN_01652 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NMFKLGDN_01653 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
NMFKLGDN_01654 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NMFKLGDN_01655 6.4e-180 M LPXTG-motif cell wall anchor domain protein
NMFKLGDN_01656 0.0 M LPXTG-motif cell wall anchor domain protein
NMFKLGDN_01657 1.1e-34 M LPXTG-motif cell wall anchor domain protein
NMFKLGDN_01658 1.1e-19 M LPXTG-motif cell wall anchor domain protein
NMFKLGDN_01659 1.1e-158 spoU 2.1.1.185 J Methyltransferase
NMFKLGDN_01660 4.9e-224 oxlT P Major Facilitator Superfamily
NMFKLGDN_01661 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NMFKLGDN_01663 1.5e-225 S cog cog1373
NMFKLGDN_01664 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
NMFKLGDN_01665 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NMFKLGDN_01666 7.3e-158 EG EamA-like transporter family
NMFKLGDN_01667 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
NMFKLGDN_01668 0.0 helD 3.6.4.12 L DNA helicase
NMFKLGDN_01669 1.2e-115 dedA S SNARE associated Golgi protein
NMFKLGDN_01670 4.2e-126 3.1.3.73 G phosphoglycerate mutase
NMFKLGDN_01671 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMFKLGDN_01672 6.6e-35 S Transglycosylase associated protein
NMFKLGDN_01674 1.6e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMFKLGDN_01675 1.4e-226 V domain protein
NMFKLGDN_01676 1.6e-94 K Transcriptional regulator (TetR family)
NMFKLGDN_01677 5.8e-39 pspC KT PspC domain protein
NMFKLGDN_01678 9.2e-150
NMFKLGDN_01679 4e-17 3.2.1.14 GH18
NMFKLGDN_01680 1.5e-82 zur P Belongs to the Fur family
NMFKLGDN_01681 5.4e-101 gmk2 2.7.4.8 F Guanylate kinase
NMFKLGDN_01682 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NMFKLGDN_01683 6.7e-254 yfnA E Amino Acid
NMFKLGDN_01684 7.2e-234 EGP Sugar (and other) transporter
NMFKLGDN_01685 8.1e-230
NMFKLGDN_01687 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
NMFKLGDN_01688 9.2e-281 L Transposase IS66 family
NMFKLGDN_01689 1.7e-183 S Phosphotransferase system, EIIC
NMFKLGDN_01690 2.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMFKLGDN_01691 6.7e-198 ylbL T Belongs to the peptidase S16 family
NMFKLGDN_01692 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NMFKLGDN_01693 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NMFKLGDN_01694 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NMFKLGDN_01695 2e-222 ftsW D Belongs to the SEDS family
NMFKLGDN_01696 0.0 typA T GTP-binding protein TypA
NMFKLGDN_01697 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NMFKLGDN_01698 1.4e-47 yktA S Belongs to the UPF0223 family
NMFKLGDN_01699 5.9e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMFKLGDN_01700 5.1e-173 scrR K Transcriptional regulator, LacI family
NMFKLGDN_01701 3e-24
NMFKLGDN_01702 8.2e-103
NMFKLGDN_01703 2.6e-214 yttB EGP Major facilitator Superfamily
NMFKLGDN_01704 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NMFKLGDN_01705 1.1e-65
NMFKLGDN_01706 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NMFKLGDN_01707 6.6e-262 S Putative peptidoglycan binding domain
NMFKLGDN_01714 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMFKLGDN_01715 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NMFKLGDN_01716 6.7e-93 dps P Belongs to the Dps family
NMFKLGDN_01717 7.9e-35 copZ C Heavy-metal-associated domain
NMFKLGDN_01718 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NMFKLGDN_01719 1.7e-103 dedA 3.1.3.1 S SNARE associated Golgi protein
NMFKLGDN_01720 2.3e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMFKLGDN_01721 7.4e-80 K AsnC family
NMFKLGDN_01722 1.5e-80 uspA T universal stress protein
NMFKLGDN_01723 1.9e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
NMFKLGDN_01724 0.0 lacS G Transporter
NMFKLGDN_01725 9.9e-192 yibE S overlaps another CDS with the same product name
NMFKLGDN_01726 6.3e-129 yibF S overlaps another CDS with the same product name
NMFKLGDN_01727 5e-232 pyrP F Permease
NMFKLGDN_01728 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
NMFKLGDN_01729 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMFKLGDN_01730 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMFKLGDN_01731 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMFKLGDN_01732 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMFKLGDN_01733 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMFKLGDN_01734 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMFKLGDN_01735 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NMFKLGDN_01736 1.3e-33 ywzB S Protein of unknown function (DUF1146)
NMFKLGDN_01737 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMFKLGDN_01738 1.9e-178 mbl D Cell shape determining protein MreB Mrl
NMFKLGDN_01739 1e-31 S Protein of unknown function (DUF2969)
NMFKLGDN_01740 4.1e-220 rodA D Belongs to the SEDS family
NMFKLGDN_01741 3.3e-46 gcvH E glycine cleavage
NMFKLGDN_01742 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NMFKLGDN_01743 3.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMFKLGDN_01744 6.8e-265 yfnA E amino acid
NMFKLGDN_01745 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMFKLGDN_01746 5.8e-40 1.3.5.4 S FMN binding
NMFKLGDN_01747 3.7e-221 norA EGP Major facilitator Superfamily
NMFKLGDN_01748 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NMFKLGDN_01749 4.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
NMFKLGDN_01750 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMFKLGDN_01751 3.1e-103 metI P ABC transporter permease
NMFKLGDN_01752 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NMFKLGDN_01753 1.2e-252 clcA P chloride
NMFKLGDN_01754 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NMFKLGDN_01755 4.5e-104 proW P ABC transporter, permease protein
NMFKLGDN_01756 1e-139 proV E ABC transporter, ATP-binding protein
NMFKLGDN_01757 6.3e-109 proWZ P ABC transporter permease
NMFKLGDN_01758 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
NMFKLGDN_01759 9e-75 K Transcriptional regulator
NMFKLGDN_01760 4.8e-154 1.6.5.2 GM NAD(P)H-binding
NMFKLGDN_01762 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
NMFKLGDN_01763 0.0 cadA P P-type ATPase
NMFKLGDN_01764 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMFKLGDN_01765 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NMFKLGDN_01766 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMFKLGDN_01767 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NMFKLGDN_01768 2.2e-202 ykiI
NMFKLGDN_01769 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMFKLGDN_01770 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMFKLGDN_01771 1e-110 K Bacterial regulatory proteins, tetR family
NMFKLGDN_01772 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NMFKLGDN_01773 3.4e-77 ctsR K Belongs to the CtsR family
NMFKLGDN_01774 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
NMFKLGDN_01775 1.3e-16 S Hydrolases of the alpha beta superfamily
NMFKLGDN_01776 1.4e-94 S Hydrolases of the alpha beta superfamily
NMFKLGDN_01782 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NMFKLGDN_01783 1.5e-275 lysP E amino acid
NMFKLGDN_01784 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
NMFKLGDN_01785 3e-119 lssY 3.6.1.27 I phosphatase
NMFKLGDN_01786 6.7e-81 S Threonine/Serine exporter, ThrE
NMFKLGDN_01787 3.6e-129 thrE S Putative threonine/serine exporter
NMFKLGDN_01788 3.5e-31 cspC K Cold shock protein
NMFKLGDN_01789 1.1e-124 sirR K iron dependent repressor
NMFKLGDN_01790 9.1e-167 czcD P cation diffusion facilitator family transporter
NMFKLGDN_01791 2.9e-117 S membrane
NMFKLGDN_01792 7.6e-110 S VIT family
NMFKLGDN_01793 2.7e-82 usp1 T Belongs to the universal stress protein A family
NMFKLGDN_01794 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NMFKLGDN_01795 3.7e-151 glnH ET ABC transporter
NMFKLGDN_01796 4.2e-110 gluC P ABC transporter permease
NMFKLGDN_01797 4e-108 glnP P ABC transporter permease
NMFKLGDN_01798 1.1e-217 S CAAX protease self-immunity
NMFKLGDN_01799 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMFKLGDN_01800 2.9e-57
NMFKLGDN_01801 2.2e-73 merR K MerR HTH family regulatory protein
NMFKLGDN_01802 7.2e-270 lmrB EGP Major facilitator Superfamily
NMFKLGDN_01803 5.8e-124 S Domain of unknown function (DUF4811)
NMFKLGDN_01804 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NMFKLGDN_01806 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMFKLGDN_01807 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NMFKLGDN_01808 3.4e-188 I Alpha beta
NMFKLGDN_01809 8.5e-282 emrY EGP Major facilitator Superfamily
NMFKLGDN_01810 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
NMFKLGDN_01811 2e-250 yjjP S Putative threonine/serine exporter
NMFKLGDN_01812 1e-159 mleR K LysR family
NMFKLGDN_01813 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
NMFKLGDN_01814 1.8e-267 frdC 1.3.5.4 C FAD binding domain
NMFKLGDN_01815 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NMFKLGDN_01816 1.2e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NMFKLGDN_01817 5.5e-161 mleR K LysR family
NMFKLGDN_01818 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMFKLGDN_01819 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NMFKLGDN_01820 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
NMFKLGDN_01821 4.2e-169 L transposase, IS605 OrfB family
NMFKLGDN_01822 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
NMFKLGDN_01823 1.5e-25
NMFKLGDN_01824 9.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NMFKLGDN_01825 3e-75
NMFKLGDN_01826 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMFKLGDN_01827 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NMFKLGDN_01828 7.9e-158 amtB P ammonium transporter
NMFKLGDN_01829 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NMFKLGDN_01831 1.3e-46
NMFKLGDN_01832 3.2e-96 S PFAM Archaeal ATPase
NMFKLGDN_01833 5.1e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NMFKLGDN_01834 1.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMFKLGDN_01835 3.5e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NMFKLGDN_01836 5.2e-50
NMFKLGDN_01837 0.0 S SEC-C Motif Domain Protein
NMFKLGDN_01839 4.2e-55 M Leucine-rich repeat (LRR) protein
NMFKLGDN_01840 6.8e-56 K Transcriptional regulator, ArsR family
NMFKLGDN_01841 1.2e-92 P Cadmium resistance transporter
NMFKLGDN_01842 1.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
NMFKLGDN_01843 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NMFKLGDN_01844 2.2e-182 ABC-SBP S ABC transporter
NMFKLGDN_01845 8.5e-73 M PFAM NLP P60 protein
NMFKLGDN_01846 1.6e-236 mepA V MATE efflux family protein
NMFKLGDN_01847 2.1e-54 trxA O Belongs to the thioredoxin family
NMFKLGDN_01848 2.3e-131 terC P membrane
NMFKLGDN_01849 2.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMFKLGDN_01850 8.2e-168 corA P CorA-like Mg2+ transporter protein
NMFKLGDN_01851 7e-289 L Transposase
NMFKLGDN_01852 1.4e-283 pipD E Dipeptidase
NMFKLGDN_01853 1.6e-241 pbuX F xanthine permease
NMFKLGDN_01854 1.8e-251 nhaC C Na H antiporter NhaC
NMFKLGDN_01855 1.4e-284 S C4-dicarboxylate anaerobic carrier
NMFKLGDN_01856 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
NMFKLGDN_01857 1.3e-41
NMFKLGDN_01858 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NMFKLGDN_01859 1.7e-207 gldA 1.1.1.6 C dehydrogenase
NMFKLGDN_01860 7.5e-123 S Alpha beta hydrolase
NMFKLGDN_01861 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMFKLGDN_01862 2.5e-101
NMFKLGDN_01864 4.1e-25 yciB M ErfK YbiS YcfS YnhG
NMFKLGDN_01865 2.2e-72 yciB M ErfK YbiS YcfS YnhG
NMFKLGDN_01866 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NMFKLGDN_01867 1.8e-84 S B3 4 domain
NMFKLGDN_01868 2.1e-91
NMFKLGDN_01869 4.8e-122 pnb C nitroreductase
NMFKLGDN_01870 1.4e-72 ogt 2.1.1.63 L Methyltransferase
NMFKLGDN_01871 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
NMFKLGDN_01872 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NMFKLGDN_01873 7.3e-69 S Protein of unknown function (DUF3021)
NMFKLGDN_01874 4.1e-77 K LytTr DNA-binding domain
NMFKLGDN_01875 2e-91 K Acetyltransferase (GNAT) family
NMFKLGDN_01876 3.1e-21
NMFKLGDN_01877 1.1e-119 ybhL S Belongs to the BI1 family
NMFKLGDN_01878 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NMFKLGDN_01879 9.3e-197 S Protein of unknown function (DUF3114)
NMFKLGDN_01880 1.8e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NMFKLGDN_01881 5e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NMFKLGDN_01882 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NMFKLGDN_01883 9.1e-62 S Domain of unknown function (DUF4828)
NMFKLGDN_01884 4.5e-191 mocA S Oxidoreductase
NMFKLGDN_01885 2.2e-227 yfmL L DEAD DEAH box helicase
NMFKLGDN_01887 7.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NMFKLGDN_01888 9.3e-56
NMFKLGDN_01889 2.3e-67 gtcA S Teichoic acid glycosylation protein
NMFKLGDN_01890 6.1e-79 fld C Flavodoxin
NMFKLGDN_01891 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
NMFKLGDN_01892 1.7e-220 arcT 2.6.1.1 E Aminotransferase
NMFKLGDN_01893 6.2e-85 E Arginine ornithine antiporter
NMFKLGDN_01894 1.4e-141 E Arginine ornithine antiporter
NMFKLGDN_01895 1.1e-281 yjeM E Amino Acid
NMFKLGDN_01896 3.2e-153 yihY S Belongs to the UPF0761 family
NMFKLGDN_01897 6.6e-34 S Protein of unknown function (DUF2922)
NMFKLGDN_01898 4.9e-31
NMFKLGDN_01899 7.9e-127 recX 2.4.1.337 GT4 S Regulatory protein RecX
NMFKLGDN_01900 4.3e-146 cps1D M Domain of unknown function (DUF4422)
NMFKLGDN_01901 5.6e-172 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NMFKLGDN_01902 3.8e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
NMFKLGDN_01903 1.6e-62 cps3F
NMFKLGDN_01904 1.2e-34 M biosynthesis protein
NMFKLGDN_01905 3.6e-66 M Domain of unknown function (DUF4422)
NMFKLGDN_01906 2.6e-78 M Core-2/I-Branching enzyme
NMFKLGDN_01907 3.5e-153 ykoT GT2 M Glycosyl transferase family 2
NMFKLGDN_01908 7.6e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
NMFKLGDN_01909 3.1e-230 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NMFKLGDN_01910 3e-73 waaB GT4 M Glycosyl transferases group 1
NMFKLGDN_01911 3.3e-51 cps3I G Acyltransferase family
NMFKLGDN_01912 1.5e-80 C Flavodoxin
NMFKLGDN_01913 6.8e-139 K LysR substrate binding domain protein
NMFKLGDN_01914 5.9e-163 1.1.1.346 C Aldo keto reductase
NMFKLGDN_01915 2.1e-39 gcvR T Belongs to the UPF0237 family
NMFKLGDN_01916 1.1e-240 XK27_08635 S UPF0210 protein
NMFKLGDN_01917 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
NMFKLGDN_01918 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMFKLGDN_01919 5.5e-153 pstA P Phosphate transport system permease protein PstA
NMFKLGDN_01920 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
NMFKLGDN_01921 8.6e-159 pstS P Phosphate
NMFKLGDN_01922 2.1e-131 K Transcriptional regulatory protein, C-terminal domain protein
NMFKLGDN_01923 1.5e-94 K Acetyltransferase (GNAT) domain
NMFKLGDN_01924 1.2e-160 S Alpha beta hydrolase
NMFKLGDN_01925 3.1e-161 gspA M family 8
NMFKLGDN_01926 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NMFKLGDN_01927 2.1e-93
NMFKLGDN_01928 1.6e-160 degV S EDD domain protein, DegV family
NMFKLGDN_01929 0.0 FbpA K Fibronectin-binding protein
NMFKLGDN_01930 6e-64 gntR1 K Transcriptional regulator, GntR family
NMFKLGDN_01931 9.5e-158 V ABC transporter, ATP-binding protein
NMFKLGDN_01932 6.7e-114
NMFKLGDN_01933 2.4e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NMFKLGDN_01934 2.4e-99 S Pfam:DUF3816
NMFKLGDN_01935 0.0 clpE O Belongs to the ClpA ClpB family
NMFKLGDN_01936 2.9e-27
NMFKLGDN_01937 2.7e-39 ptsH G phosphocarrier protein HPR
NMFKLGDN_01938 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMFKLGDN_01948 4.5e-131 2.4.1.52 GT4 M Glycosyl transferases group 1
NMFKLGDN_01949 8.6e-202 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NMFKLGDN_01950 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMFKLGDN_01951 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NMFKLGDN_01952 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NMFKLGDN_01953 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMFKLGDN_01954 2e-274 lpdA 1.8.1.4 C Dehydrogenase
NMFKLGDN_01955 1.7e-78 I alpha/beta hydrolase fold
NMFKLGDN_01956 8.5e-20 K Helix-turn-helix XRE-family like proteins
NMFKLGDN_01957 1.1e-35 S Phage derived protein Gp49-like (DUF891)
NMFKLGDN_01959 2e-45 yrvD S Pfam:DUF1049
NMFKLGDN_01960 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
NMFKLGDN_01961 8.1e-90 ntd 2.4.2.6 F Nucleoside
NMFKLGDN_01962 1.3e-20
NMFKLGDN_01963 4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
NMFKLGDN_01964 6.2e-114 yviA S Protein of unknown function (DUF421)
NMFKLGDN_01965 3.1e-72 S Protein of unknown function (DUF3290)
NMFKLGDN_01966 2.1e-41 ybaN S Protein of unknown function (DUF454)
NMFKLGDN_01967 8.1e-109 GT4 M Glycosyltransferase, group 1 family protein
NMFKLGDN_01968 4.1e-56 M Glycosyltransferase like family 2
NMFKLGDN_01969 6.1e-66 S Core-2/I-Branching enzyme
NMFKLGDN_01970 1.7e-119 S Membrane protein involved in the export of O-antigen and teichoic acid
NMFKLGDN_01971 2.6e-11 2.3.1.30, 6.2.1.41 E Bacterial transferase hexapeptide (six repeats)
NMFKLGDN_01972 3.4e-54 MA20_43635 M Capsular polysaccharide synthesis protein
NMFKLGDN_01973 1.9e-51 M Glycosyltransferase like family 2
NMFKLGDN_01974 5.4e-20 S EpsG family
NMFKLGDN_01975 1.6e-61 M Glycosyltransferase, group 1 family protein
NMFKLGDN_01976 1.3e-58 M Glycosyl transferases group 1
NMFKLGDN_01977 2.4e-105 rfbP M Bacterial sugar transferase
NMFKLGDN_01978 7.5e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NMFKLGDN_01979 4.6e-136 epsB M biosynthesis protein
NMFKLGDN_01980 1.2e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NMFKLGDN_01981 2.3e-66 K Transcriptional regulator, HxlR family
NMFKLGDN_01982 7e-130
NMFKLGDN_01983 7.1e-101 K DNA-templated transcription, initiation
NMFKLGDN_01984 6.6e-37
NMFKLGDN_01985 4e-25
NMFKLGDN_01987 1.3e-70 O Preprotein translocase subunit SecB
NMFKLGDN_01988 1.4e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NMFKLGDN_01989 1.7e-249 mmuP E amino acid
NMFKLGDN_01991 4.8e-66 T Toxin-antitoxin system, toxin component, MazF family
NMFKLGDN_01992 1e-37
NMFKLGDN_01993 1.5e-06 D nuclear chromosome segregation
NMFKLGDN_01994 0.0 snf 2.7.11.1 KL domain protein
NMFKLGDN_01995 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
NMFKLGDN_01996 7.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NMFKLGDN_01997 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NMFKLGDN_01998 1.6e-27
NMFKLGDN_01999 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMFKLGDN_02000 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMFKLGDN_02001 3.1e-193 yeaN P Transporter, major facilitator family protein
NMFKLGDN_02002 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
NMFKLGDN_02003 9.9e-85 nrdI F Belongs to the NrdI family
NMFKLGDN_02004 6.2e-241 yhdP S Transporter associated domain
NMFKLGDN_02005 1.7e-154 ypdB V (ABC) transporter
NMFKLGDN_02006 4.8e-88 GM epimerase
NMFKLGDN_02007 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
NMFKLGDN_02008 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
NMFKLGDN_02009 7.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
NMFKLGDN_02010 4e-234 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMFKLGDN_02011 7.4e-129 narI 1.7.5.1 C Nitrate reductase
NMFKLGDN_02012 2.7e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
NMFKLGDN_02013 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
NMFKLGDN_02014 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMFKLGDN_02015 8.8e-187 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NMFKLGDN_02016 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NMFKLGDN_02017 8.5e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NMFKLGDN_02018 5.1e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NMFKLGDN_02019 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NMFKLGDN_02020 3e-44
NMFKLGDN_02021 1.8e-190 comP 2.7.13.3 F Sensor histidine kinase
NMFKLGDN_02022 1.4e-24 nreC K PFAM regulatory protein LuxR
NMFKLGDN_02023 2.3e-60 nreC K PFAM regulatory protein LuxR
NMFKLGDN_02024 1.6e-18
NMFKLGDN_02025 3.6e-182
NMFKLGDN_02026 2.9e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
NMFKLGDN_02027 8.8e-77 yphH S Cupin domain
NMFKLGDN_02028 1.7e-73 yeaL S UPF0756 membrane protein
NMFKLGDN_02029 6.9e-243 EGP Major facilitator Superfamily
NMFKLGDN_02030 5e-75 copY K Copper transport repressor CopY TcrY
NMFKLGDN_02031 2.5e-245 yhdP S Transporter associated domain
NMFKLGDN_02032 0.0 ubiB S ABC1 family
NMFKLGDN_02033 9.6e-144 S DUF218 domain
NMFKLGDN_02034 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMFKLGDN_02035 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMFKLGDN_02036 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMFKLGDN_02037 0.0 uvrA3 L excinuclease ABC, A subunit
NMFKLGDN_02038 4.6e-123 S SNARE associated Golgi protein
NMFKLGDN_02039 1.3e-229 N Uncharacterized conserved protein (DUF2075)
NMFKLGDN_02040 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NMFKLGDN_02042 1e-254 yifK E Amino acid permease
NMFKLGDN_02043 1.2e-157 endA V DNA/RNA non-specific endonuclease
NMFKLGDN_02044 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMFKLGDN_02045 4.6e-258 ysaB V FtsX-like permease family
NMFKLGDN_02046 5.3e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NMFKLGDN_02047 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMFKLGDN_02048 4.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMFKLGDN_02049 2.1e-197 EGP Major facilitator Superfamily
NMFKLGDN_02050 5.6e-86 ymdB S Macro domain protein
NMFKLGDN_02051 4.2e-110 K Helix-turn-helix domain
NMFKLGDN_02052 0.0 pepO 3.4.24.71 O Peptidase family M13
NMFKLGDN_02053 5.1e-47
NMFKLGDN_02054 9.3e-242 S Putative metallopeptidase domain
NMFKLGDN_02055 3e-204 3.1.3.1 S associated with various cellular activities
NMFKLGDN_02056 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NMFKLGDN_02057 1.6e-64 yeaO S Protein of unknown function, DUF488
NMFKLGDN_02059 2.9e-117 yrkL S Flavodoxin-like fold
NMFKLGDN_02060 9.5e-55
NMFKLGDN_02061 2e-15 S Domain of unknown function (DUF4767)
NMFKLGDN_02062 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NMFKLGDN_02063 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NMFKLGDN_02064 6.9e-49
NMFKLGDN_02066 7.6e-205 nrnB S DHHA1 domain
NMFKLGDN_02067 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
NMFKLGDN_02068 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
NMFKLGDN_02069 2e-106 NU mannosyl-glycoprotein
NMFKLGDN_02070 2.3e-142 S Putative ABC-transporter type IV
NMFKLGDN_02071 7.8e-272 S ABC transporter, ATP-binding protein
NMFKLGDN_02072 8.2e-48

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)