ORF_ID e_value Gene_name EC_number CAZy COGs Description
HHLPMJGF_00001 4.8e-39 L Integrase core domain
HHLPMJGF_00004 6.2e-94 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HHLPMJGF_00005 7.4e-40 L Integrase core domain
HHLPMJGF_00006 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HHLPMJGF_00008 4.6e-196 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HHLPMJGF_00009 1.1e-225 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HHLPMJGF_00010 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHLPMJGF_00011 1.3e-154 asp3 S Accessory Sec secretory system ASP3
HHLPMJGF_00012 2.4e-217 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HHLPMJGF_00013 2.6e-195 M transferase activity, transferring glycosyl groups
HHLPMJGF_00014 2.8e-144 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HHLPMJGF_00015 2.6e-191 nss M transferase activity, transferring glycosyl groups
HHLPMJGF_00017 2.4e-158 S Peptidase, M23
HHLPMJGF_00018 1.7e-28 S Acyltransferase family
HHLPMJGF_00020 5e-50 S Glycosyltransferase, group 2 family protein
HHLPMJGF_00021 7.2e-29 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HHLPMJGF_00022 3.2e-29 M PFAM Glycosyl transferase family 2
HHLPMJGF_00023 7.1e-29 M Glycosyltransferase sugar-binding region containing DXD motif
HHLPMJGF_00024 1.7e-72 cps2I S Psort location CytoplasmicMembrane, score
HHLPMJGF_00026 2.4e-42 M Pfam:DUF1792
HHLPMJGF_00027 2e-66 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HHLPMJGF_00028 3.5e-86 GT4 G Glycosyl transferase 4-like
HHLPMJGF_00029 6.8e-49 pglC M Bacterial sugar transferase
HHLPMJGF_00030 3e-107 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HHLPMJGF_00031 3.5e-32 epsB M biosynthesis protein
HHLPMJGF_00032 1.1e-83 F Belongs to the NrdI family
HHLPMJGF_00033 2.8e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HHLPMJGF_00034 9.9e-70 rnhA 3.1.26.4 L Ribonuclease HI
HHLPMJGF_00035 1.5e-65 esbA S Family of unknown function (DUF5322)
HHLPMJGF_00036 2.9e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHLPMJGF_00037 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHLPMJGF_00038 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
HHLPMJGF_00039 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HHLPMJGF_00040 0.0 FbpA K Fibronectin-binding protein
HHLPMJGF_00041 1.9e-161 degV S EDD domain protein, DegV family
HHLPMJGF_00042 6.8e-74
HHLPMJGF_00043 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHLPMJGF_00044 1.1e-158 gspA M family 8
HHLPMJGF_00045 1.2e-160 S Alpha beta hydrolase
HHLPMJGF_00046 1.5e-94 K Acetyltransferase (GNAT) domain
HHLPMJGF_00047 5.1e-151 XK27_08635 S UPF0210 protein
HHLPMJGF_00048 8.5e-73 XK27_08635 S UPF0210 protein
HHLPMJGF_00049 2.1e-39 gcvR T Belongs to the UPF0237 family
HHLPMJGF_00050 1.9e-169 1.1.1.346 C Aldo keto reductase
HHLPMJGF_00051 1.1e-158 K LysR substrate binding domain protein
HHLPMJGF_00052 3.2e-83 C Flavodoxin
HHLPMJGF_00053 5.6e-79 yphH S Cupin domain
HHLPMJGF_00054 1e-73 yeaL S UPF0756 membrane protein
HHLPMJGF_00055 1.3e-244 EGP Major facilitator Superfamily
HHLPMJGF_00056 5e-75 copY K Copper transport repressor CopY TcrY
HHLPMJGF_00057 2.5e-245 yhdP S Transporter associated domain
HHLPMJGF_00058 0.0 ubiB S ABC1 family
HHLPMJGF_00059 8.1e-143 S DUF218 domain
HHLPMJGF_00060 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHLPMJGF_00061 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHLPMJGF_00062 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHLPMJGF_00063 0.0 uvrA3 L excinuclease ABC, A subunit
HHLPMJGF_00064 4.6e-123 S SNARE associated Golgi protein
HHLPMJGF_00065 2.5e-228 N Uncharacterized conserved protein (DUF2075)
HHLPMJGF_00066 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHLPMJGF_00068 1e-254 yifK E Amino acid permease
HHLPMJGF_00069 5.5e-158 endA V DNA/RNA non-specific endonuclease
HHLPMJGF_00070 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHLPMJGF_00072 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHLPMJGF_00074 8.9e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HHLPMJGF_00075 5.9e-274 pipD E Dipeptidase
HHLPMJGF_00076 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHLPMJGF_00077 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHLPMJGF_00078 0.0 dnaK O Heat shock 70 kDa protein
HHLPMJGF_00079 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHLPMJGF_00080 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHLPMJGF_00081 5.8e-64
HHLPMJGF_00082 0.0 bamA GM domain, Protein
HHLPMJGF_00083 7.9e-64 gntR1 K Transcriptional regulator, GntR family
HHLPMJGF_00084 7.2e-158 V ABC transporter, ATP-binding protein
HHLPMJGF_00085 4.3e-113
HHLPMJGF_00086 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HHLPMJGF_00087 5.4e-99 S Pfam:DUF3816
HHLPMJGF_00088 0.0 clpE O Belongs to the ClpA ClpB family
HHLPMJGF_00089 2.9e-27
HHLPMJGF_00090 2.7e-39 ptsH G phosphocarrier protein HPR
HHLPMJGF_00091 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHLPMJGF_00092 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HHLPMJGF_00093 9.4e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
HHLPMJGF_00094 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHLPMJGF_00095 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
HHLPMJGF_00096 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HHLPMJGF_00097 6.7e-93 dps P Belongs to the Dps family
HHLPMJGF_00098 7.9e-35 copZ C Heavy-metal-associated domain
HHLPMJGF_00099 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HHLPMJGF_00101 1.9e-159 yjcE P Sodium proton antiporter
HHLPMJGF_00102 1.6e-74 yjcE P Sodium proton antiporter
HHLPMJGF_00104 3.2e-36
HHLPMJGF_00105 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HHLPMJGF_00106 1.1e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHLPMJGF_00107 2.9e-310 lmrA V ABC transporter, ATP-binding protein
HHLPMJGF_00108 0.0 yfiC V ABC transporter
HHLPMJGF_00109 1.1e-283 pipD E Dipeptidase
HHLPMJGF_00110 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHLPMJGF_00111 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
HHLPMJGF_00112 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HHLPMJGF_00113 1e-243 yagE E amino acid
HHLPMJGF_00114 4.5e-140 aroD S Serine hydrolase (FSH1)
HHLPMJGF_00115 1.1e-240 brnQ U Component of the transport system for branched-chain amino acids
HHLPMJGF_00116 8.9e-167 GK ROK family
HHLPMJGF_00117 0.0 tetP J elongation factor G
HHLPMJGF_00118 5.1e-81 uspA T universal stress protein
HHLPMJGF_00119 8.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HHLPMJGF_00120 7.1e-63
HHLPMJGF_00121 1.8e-14
HHLPMJGF_00122 1.4e-212 EGP Major facilitator Superfamily
HHLPMJGF_00123 1.3e-257 G PTS system Galactitol-specific IIC component
HHLPMJGF_00124 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
HHLPMJGF_00125 1.1e-161
HHLPMJGF_00126 1e-72 K Transcriptional regulator
HHLPMJGF_00127 3.7e-190 D Alpha beta
HHLPMJGF_00128 2.2e-52 ypaA S Protein of unknown function (DUF1304)
HHLPMJGF_00129 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HHLPMJGF_00130 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHLPMJGF_00131 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHLPMJGF_00132 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHLPMJGF_00133 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHLPMJGF_00134 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHLPMJGF_00135 2.8e-31 yajC U Preprotein translocase
HHLPMJGF_00136 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HHLPMJGF_00137 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHLPMJGF_00138 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHLPMJGF_00139 4.1e-43 yrzL S Belongs to the UPF0297 family
HHLPMJGF_00140 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHLPMJGF_00141 6.1e-48 yrzB S Belongs to the UPF0473 family
HHLPMJGF_00142 1e-85 cvpA S Colicin V production protein
HHLPMJGF_00143 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHLPMJGF_00144 6.1e-54 trxA O Belongs to the thioredoxin family
HHLPMJGF_00145 1.3e-96 yslB S Protein of unknown function (DUF2507)
HHLPMJGF_00146 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HHLPMJGF_00147 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHLPMJGF_00148 4.4e-94 S Phosphoesterase
HHLPMJGF_00149 3.6e-76 ykuL S (CBS) domain
HHLPMJGF_00150 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HHLPMJGF_00151 3.4e-147 ykuT M mechanosensitive ion channel
HHLPMJGF_00152 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHLPMJGF_00153 3.5e-26
HHLPMJGF_00154 1.2e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HHLPMJGF_00155 1.4e-181 ccpA K catabolite control protein A
HHLPMJGF_00156 1.9e-134
HHLPMJGF_00157 3.5e-132 yebC K Transcriptional regulatory protein
HHLPMJGF_00158 1.7e-179 comGA NU Type II IV secretion system protein
HHLPMJGF_00159 3.6e-180 comGB NU type II secretion system
HHLPMJGF_00160 7.1e-47 comGC U competence protein ComGC
HHLPMJGF_00161 8.3e-78 NU general secretion pathway protein
HHLPMJGF_00162 2.7e-40
HHLPMJGF_00163 6.3e-70
HHLPMJGF_00165 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
HHLPMJGF_00166 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHLPMJGF_00167 2.2e-113 S Calcineurin-like phosphoesterase
HHLPMJGF_00168 1.3e-93 yutD S Protein of unknown function (DUF1027)
HHLPMJGF_00169 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHLPMJGF_00170 2.4e-105 S Protein of unknown function (DUF1461)
HHLPMJGF_00171 5.5e-110 dedA S SNARE-like domain protein
HHLPMJGF_00172 1e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHLPMJGF_00173 5.1e-187 yegS 2.7.1.107 G Lipid kinase
HHLPMJGF_00174 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHLPMJGF_00175 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHLPMJGF_00176 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHLPMJGF_00177 2.1e-202 camS S sex pheromone
HHLPMJGF_00178 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHLPMJGF_00179 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HHLPMJGF_00180 1.1e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HHLPMJGF_00181 1.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHLPMJGF_00182 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
HHLPMJGF_00183 3.6e-140 IQ reductase
HHLPMJGF_00184 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HHLPMJGF_00185 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHLPMJGF_00186 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HHLPMJGF_00187 3e-203 coiA 3.6.4.12 S Competence protein
HHLPMJGF_00188 9.2e-264 pipD E Dipeptidase
HHLPMJGF_00189 4.7e-114 yjbH Q Thioredoxin
HHLPMJGF_00190 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HHLPMJGF_00191 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHLPMJGF_00192 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HHLPMJGF_00193 1.1e-113 frnE Q DSBA-like thioredoxin domain
HHLPMJGF_00194 1.4e-51
HHLPMJGF_00195 9.3e-189 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00196 4e-28 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00197 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HHLPMJGF_00199 2.5e-225 S cog cog1373
HHLPMJGF_00200 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HHLPMJGF_00201 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHLPMJGF_00202 4.7e-157 EG EamA-like transporter family
HHLPMJGF_00203 8.1e-36 Q pyridine nucleotide-disulphide oxidoreductase
HHLPMJGF_00204 0.0 helD 3.6.4.12 L DNA helicase
HHLPMJGF_00205 1.2e-115 dedA S SNARE associated Golgi protein
HHLPMJGF_00206 4.2e-126 3.1.3.73 G phosphoglycerate mutase
HHLPMJGF_00207 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHLPMJGF_00208 6.6e-35 S Transglycosylase associated protein
HHLPMJGF_00210 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHLPMJGF_00211 4.8e-222 V domain protein
HHLPMJGF_00212 1.6e-94 K Transcriptional regulator (TetR family)
HHLPMJGF_00213 5.8e-39 pspC KT PspC domain protein
HHLPMJGF_00214 9.2e-150
HHLPMJGF_00215 4e-17 3.2.1.14 GH18
HHLPMJGF_00216 1.5e-82 zur P Belongs to the Fur family
HHLPMJGF_00217 1.2e-100 gmk2 2.7.4.8 F Guanylate kinase
HHLPMJGF_00218 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HHLPMJGF_00219 3e-254 yfnA E Amino Acid
HHLPMJGF_00220 2.1e-197 EGP Sugar (and other) transporter
HHLPMJGF_00221 2.7e-27 EGP Sugar (and other) transporter
HHLPMJGF_00222 8.1e-230
HHLPMJGF_00223 4.3e-208 potD P ABC transporter
HHLPMJGF_00224 4.9e-140 potC P ABC transporter permease
HHLPMJGF_00225 4.5e-146 potB P ABC transporter permease
HHLPMJGF_00226 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHLPMJGF_00227 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HHLPMJGF_00228 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HHLPMJGF_00229 0.0 pacL 3.6.3.8 P P-type ATPase
HHLPMJGF_00230 3.4e-85 dps P Belongs to the Dps family
HHLPMJGF_00231 1.1e-242 yagE E amino acid
HHLPMJGF_00232 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HHLPMJGF_00233 9e-58 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHLPMJGF_00234 2.5e-127 L Helix-turn-helix domain
HHLPMJGF_00235 6.7e-150 L hmm pf00665
HHLPMJGF_00236 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HHLPMJGF_00237 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HHLPMJGF_00238 2.5e-138 IQ KR domain
HHLPMJGF_00239 3.3e-133 S membrane transporter protein
HHLPMJGF_00240 3e-96 S ABC-type cobalt transport system, permease component
HHLPMJGF_00241 1.6e-247 cbiO1 S ABC transporter, ATP-binding protein
HHLPMJGF_00242 1.8e-113 P Cobalt transport protein
HHLPMJGF_00243 1.6e-52 yvlA
HHLPMJGF_00244 0.0 yjcE P Sodium proton antiporter
HHLPMJGF_00245 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHLPMJGF_00246 9.7e-173
HHLPMJGF_00247 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHLPMJGF_00248 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
HHLPMJGF_00249 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HHLPMJGF_00250 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHLPMJGF_00251 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HHLPMJGF_00252 1.4e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHLPMJGF_00253 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHLPMJGF_00254 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHLPMJGF_00255 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHLPMJGF_00256 2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HHLPMJGF_00257 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHLPMJGF_00258 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHLPMJGF_00259 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHLPMJGF_00260 1.6e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HHLPMJGF_00261 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HHLPMJGF_00262 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HHLPMJGF_00263 1.9e-176 K AI-2E family transporter
HHLPMJGF_00264 3.9e-140 L hmm pf00665
HHLPMJGF_00265 2.1e-95 L Helix-turn-helix domain
HHLPMJGF_00266 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HHLPMJGF_00267 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HHLPMJGF_00268 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HHLPMJGF_00269 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HHLPMJGF_00270 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
HHLPMJGF_00271 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
HHLPMJGF_00272 1.7e-207 araR K Transcriptional regulator
HHLPMJGF_00273 4.3e-83 usp6 T universal stress protein
HHLPMJGF_00274 4.4e-46
HHLPMJGF_00275 1.7e-235 rarA L recombination factor protein RarA
HHLPMJGF_00276 7.1e-86 yueI S Protein of unknown function (DUF1694)
HHLPMJGF_00277 1.5e-21
HHLPMJGF_00278 8.1e-75 4.4.1.5 E Glyoxalase
HHLPMJGF_00279 2.5e-138 S Membrane
HHLPMJGF_00280 2.5e-135 S Belongs to the UPF0246 family
HHLPMJGF_00281 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HHLPMJGF_00282 1.6e-171 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHLPMJGF_00283 3.1e-65 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHLPMJGF_00284 1.1e-235 pbuG S permease
HHLPMJGF_00285 3.9e-140 L hmm pf00665
HHLPMJGF_00286 2.1e-95 L Helix-turn-helix domain
HHLPMJGF_00287 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
HHLPMJGF_00288 2e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHLPMJGF_00289 5.5e-153 pstA P Phosphate transport system permease protein PstA
HHLPMJGF_00290 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
HHLPMJGF_00291 7.3e-158 pstS P Phosphate
HHLPMJGF_00292 1.5e-132 K Transcriptional regulatory protein, C-terminal domain protein
HHLPMJGF_00293 2.1e-95 L Helix-turn-helix domain
HHLPMJGF_00294 3.9e-140 L hmm pf00665
HHLPMJGF_00295 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HHLPMJGF_00296 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHLPMJGF_00297 5.5e-217 patA 2.6.1.1 E Aminotransferase
HHLPMJGF_00298 1.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHLPMJGF_00299 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHLPMJGF_00300 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHLPMJGF_00301 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHLPMJGF_00302 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHLPMJGF_00303 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HHLPMJGF_00304 6.5e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHLPMJGF_00306 5.8e-129 L hmm pf00665
HHLPMJGF_00307 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HHLPMJGF_00308 1.7e-84 F NUDIX domain
HHLPMJGF_00309 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHLPMJGF_00310 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHLPMJGF_00311 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHLPMJGF_00312 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
HHLPMJGF_00313 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHLPMJGF_00314 2.4e-161 dprA LU DNA protecting protein DprA
HHLPMJGF_00315 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHLPMJGF_00316 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHLPMJGF_00317 4.4e-35 yozE S Belongs to the UPF0346 family
HHLPMJGF_00318 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HHLPMJGF_00319 9.5e-172 ypmR E lipolytic protein G-D-S-L family
HHLPMJGF_00320 1.7e-151 DegV S EDD domain protein, DegV family
HHLPMJGF_00321 5.3e-113 hlyIII S protein, hemolysin III
HHLPMJGF_00322 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHLPMJGF_00323 7.7e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHLPMJGF_00324 0.0 yfmR S ABC transporter, ATP-binding protein
HHLPMJGF_00325 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHLPMJGF_00326 1.5e-236 S Tetratricopeptide repeat protein
HHLPMJGF_00327 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHLPMJGF_00328 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HHLPMJGF_00329 2.5e-204 rpsA 1.17.7.4 J Ribosomal protein S1
HHLPMJGF_00330 6e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HHLPMJGF_00331 8.5e-14 M Lysin motif
HHLPMJGF_00332 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HHLPMJGF_00333 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
HHLPMJGF_00334 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHLPMJGF_00335 4.2e-127 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHLPMJGF_00336 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHLPMJGF_00337 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHLPMJGF_00338 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHLPMJGF_00339 1.2e-163 xerD D recombinase XerD
HHLPMJGF_00340 2.3e-167 cvfB S S1 domain
HHLPMJGF_00341 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HHLPMJGF_00342 0.0 dnaE 2.7.7.7 L DNA polymerase
HHLPMJGF_00343 3.1e-30 S Protein of unknown function (DUF2929)
HHLPMJGF_00344 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHLPMJGF_00345 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHLPMJGF_00346 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
HHLPMJGF_00347 1.2e-219 patA 2.6.1.1 E Aminotransferase
HHLPMJGF_00348 1.9e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHLPMJGF_00349 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHLPMJGF_00350 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HHLPMJGF_00351 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HHLPMJGF_00352 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
HHLPMJGF_00353 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHLPMJGF_00354 9.9e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HHLPMJGF_00355 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHLPMJGF_00356 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
HHLPMJGF_00357 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHLPMJGF_00358 9.6e-90 bioY S BioY family
HHLPMJGF_00359 3.9e-262 argH 4.3.2.1 E argininosuccinate lyase
HHLPMJGF_00360 8.6e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHLPMJGF_00361 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHLPMJGF_00362 1e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HHLPMJGF_00363 2.2e-87
HHLPMJGF_00364 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HHLPMJGF_00365 2.6e-214 yttB EGP Major facilitator Superfamily
HHLPMJGF_00366 8.2e-103
HHLPMJGF_00367 3e-24
HHLPMJGF_00368 2.5e-172 scrR K Transcriptional regulator, LacI family
HHLPMJGF_00369 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHLPMJGF_00370 3.5e-49 czrA K Transcriptional regulator, ArsR family
HHLPMJGF_00371 7.1e-39
HHLPMJGF_00372 0.0 yhcA V ABC transporter, ATP-binding protein
HHLPMJGF_00373 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HHLPMJGF_00374 4.7e-183 hrtB V ABC transporter permease
HHLPMJGF_00375 2.6e-86 ygfC K transcriptional regulator (TetR family)
HHLPMJGF_00376 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HHLPMJGF_00377 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
HHLPMJGF_00378 3e-34
HHLPMJGF_00379 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHLPMJGF_00380 5.8e-129 L hmm pf00665
HHLPMJGF_00382 3.4e-11 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
HHLPMJGF_00385 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_00386 1.6e-45 yrvD S Pfam:DUF1049
HHLPMJGF_00387 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
HHLPMJGF_00388 8.1e-90 ntd 2.4.2.6 F Nucleoside
HHLPMJGF_00389 1.3e-20
HHLPMJGF_00390 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
HHLPMJGF_00391 6.2e-114 yviA S Protein of unknown function (DUF421)
HHLPMJGF_00392 1.6e-71 S Protein of unknown function (DUF3290)
HHLPMJGF_00393 5.9e-114 L PFAM Integrase catalytic region
HHLPMJGF_00394 5.9e-114 L PFAM Integrase catalytic region
HHLPMJGF_00395 4.9e-224 oxlT P Major Facilitator Superfamily
HHLPMJGF_00396 1.1e-158 spoU 2.1.1.185 J Methyltransferase
HHLPMJGF_00397 2e-74 ogt 2.1.1.63 L Methyltransferase
HHLPMJGF_00398 4.8e-122 pnb C nitroreductase
HHLPMJGF_00399 2.1e-91
HHLPMJGF_00400 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_00401 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHLPMJGF_00402 5.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HHLPMJGF_00403 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HHLPMJGF_00404 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HHLPMJGF_00405 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
HHLPMJGF_00406 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHLPMJGF_00407 1.3e-57 yabA L Involved in initiation control of chromosome replication
HHLPMJGF_00408 8.2e-185 holB 2.7.7.7 L DNA polymerase III
HHLPMJGF_00409 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HHLPMJGF_00410 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHLPMJGF_00411 9.7e-39 S Protein of unknown function (DUF2508)
HHLPMJGF_00412 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHLPMJGF_00413 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHLPMJGF_00414 5.3e-291 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHLPMJGF_00415 1.3e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHLPMJGF_00416 3.4e-35 nrdH O Glutaredoxin
HHLPMJGF_00417 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHLPMJGF_00418 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHLPMJGF_00419 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHLPMJGF_00420 6.4e-126 S Putative adhesin
HHLPMJGF_00421 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
HHLPMJGF_00422 4e-56 K transcriptional regulator PadR family
HHLPMJGF_00423 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHLPMJGF_00425 1.2e-230 L Integrase core domain
HHLPMJGF_00426 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHLPMJGF_00427 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
HHLPMJGF_00428 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHLPMJGF_00429 7.4e-141 ymfM S Helix-turn-helix domain
HHLPMJGF_00430 3.2e-250 ymfH S Peptidase M16
HHLPMJGF_00431 1.6e-230 ymfF S Peptidase M16 inactive domain protein
HHLPMJGF_00432 2.6e-160 aatB ET ABC transporter substrate-binding protein
HHLPMJGF_00433 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHLPMJGF_00434 3.2e-102 glnP P ABC transporter permease
HHLPMJGF_00435 1.2e-91 mreD M rod shape-determining protein MreD
HHLPMJGF_00436 8.5e-151 mreC M Involved in formation and maintenance of cell shape
HHLPMJGF_00437 1.7e-179 mreB D cell shape determining protein MreB
HHLPMJGF_00438 6.8e-121 radC L DNA repair protein
HHLPMJGF_00439 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHLPMJGF_00440 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
HHLPMJGF_00441 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HHLPMJGF_00442 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HHLPMJGF_00443 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HHLPMJGF_00444 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
HHLPMJGF_00445 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHLPMJGF_00446 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHLPMJGF_00447 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HHLPMJGF_00448 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHLPMJGF_00449 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHLPMJGF_00450 2.8e-165 L Transposase
HHLPMJGF_00452 2e-155 D CobQ CobB MinD ParA nucleotide binding domain protein
HHLPMJGF_00453 2.1e-45
HHLPMJGF_00454 2.1e-40 vsr L DNA mismatch endonuclease Vsr
HHLPMJGF_00455 2.3e-100 2.1.1.37 H C-5 cytosine-specific DNA methylase
HHLPMJGF_00456 3e-131 V AAA domain (dynein-related subfamily)
HHLPMJGF_00457 4e-93 S McrBC 5-methylcytosine restriction system component
HHLPMJGF_00458 2e-19
HHLPMJGF_00459 8.1e-127 S KAP family P-loop domain
HHLPMJGF_00460 1.8e-67 L Integrase
HHLPMJGF_00463 4.1e-16 rfbP M Bacterial sugar transferase
HHLPMJGF_00464 1.9e-114 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HHLPMJGF_00465 6.9e-132 epsB M biosynthesis protein
HHLPMJGF_00466 2.1e-161 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHLPMJGF_00467 2e-40 K Transcriptional regulator, HxlR family
HHLPMJGF_00468 2.5e-230 L transposase, IS605 OrfB family
HHLPMJGF_00469 2.1e-60 L PFAM transposase IS200-family protein
HHLPMJGF_00470 7.9e-35 L PFAM Integrase catalytic region
HHLPMJGF_00471 1.7e-237 L Helicase C-terminal domain protein
HHLPMJGF_00472 7.6e-27 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HHLPMJGF_00473 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HHLPMJGF_00474 2e-74 rplI J Binds to the 23S rRNA
HHLPMJGF_00475 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HHLPMJGF_00476 9.9e-206 yttB EGP Major facilitator Superfamily
HHLPMJGF_00477 3.7e-54
HHLPMJGF_00478 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HHLPMJGF_00479 9.8e-09 K DNA-binding helix-turn-helix protein
HHLPMJGF_00480 2.3e-78 O Bacterial dnaA protein
HHLPMJGF_00481 1.6e-52 azlD S branched-chain amino acid
HHLPMJGF_00482 3.7e-136 azlC E AzlC protein
HHLPMJGF_00483 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
HHLPMJGF_00484 1.2e-123 K response regulator
HHLPMJGF_00485 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHLPMJGF_00486 9.5e-172 deoR K sugar-binding domain protein
HHLPMJGF_00487 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HHLPMJGF_00488 2.7e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HHLPMJGF_00489 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHLPMJGF_00490 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHLPMJGF_00491 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
HHLPMJGF_00492 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHLPMJGF_00493 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
HHLPMJGF_00494 1.7e-154 spo0J K Belongs to the ParB family
HHLPMJGF_00495 3.9e-139 soj D Sporulation initiation inhibitor
HHLPMJGF_00496 4.3e-151 noc K Belongs to the ParB family
HHLPMJGF_00497 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HHLPMJGF_00498 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HHLPMJGF_00499 5.6e-169 rihC 3.2.2.1 F Nucleoside
HHLPMJGF_00500 2.3e-218 nupG F Nucleoside transporter
HHLPMJGF_00501 7.2e-221 cycA E Amino acid permease
HHLPMJGF_00503 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHLPMJGF_00504 2.8e-263 glnP P ABC transporter
HHLPMJGF_00505 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHLPMJGF_00506 5.8e-129 L hmm pf00665
HHLPMJGF_00507 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00508 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HHLPMJGF_00509 4.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HHLPMJGF_00510 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00512 1.7e-172 M hydrolase, family 25
HHLPMJGF_00513 8.5e-57 S Bacteriophage holin family
HHLPMJGF_00514 9e-36 E GDSL-like Lipase/Acylhydrolase
HHLPMJGF_00516 8.1e-196 M Prophage endopeptidase tail
HHLPMJGF_00517 1.5e-77 S phage tail
HHLPMJGF_00518 1.7e-71 D Phage tail tape measure protein, TP901 family
HHLPMJGF_00519 1.9e-24
HHLPMJGF_00520 4.4e-29 S Pfam:Phage_TAC_12
HHLPMJGF_00521 5.5e-48 S Phage major tail protein 2
HHLPMJGF_00522 3.3e-25 S Protein of unknown function (DUF3168)
HHLPMJGF_00523 1.6e-24 S Bacteriophage HK97-gp10, putative tail-component
HHLPMJGF_00524 6.2e-13
HHLPMJGF_00525 6.5e-34 S Phage gp6-like head-tail connector protein
HHLPMJGF_00526 3.2e-97
HHLPMJGF_00527 1.7e-31 S aminoacyl-tRNA ligase activity
HHLPMJGF_00529 2.7e-103 K cell adhesion
HHLPMJGF_00530 4.9e-134 S Phage portal protein
HHLPMJGF_00531 2.2e-187 S Phage terminase, large subunit
HHLPMJGF_00532 2.6e-60 L Terminase small subunit
HHLPMJGF_00533 2.4e-08
HHLPMJGF_00537 4.3e-23
HHLPMJGF_00547 1.9e-13 xre K Transcriptional
HHLPMJGF_00551 9.8e-53 S VRR_NUC
HHLPMJGF_00552 8.4e-126 S Virulence-associated protein E
HHLPMJGF_00553 1.1e-83 S Bifunctional DNA primase/polymerase, N-terminal
HHLPMJGF_00554 3.8e-30
HHLPMJGF_00555 5.1e-85 L AAA domain
HHLPMJGF_00556 1.3e-153 res L Helicase C-terminal domain protein
HHLPMJGF_00557 9.2e-33 S Siphovirus Gp157
HHLPMJGF_00562 7e-16 3.4.21.88 K Helix-turn-helix
HHLPMJGF_00563 2.5e-16 E IrrE N-terminal-like domain
HHLPMJGF_00564 2.1e-09
HHLPMJGF_00565 1.9e-60 L Belongs to the 'phage' integrase family
HHLPMJGF_00566 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00567 2.1e-224 L Transposase IS66 family
HHLPMJGF_00569 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHLPMJGF_00570 2.4e-65 K HxlR-like helix-turn-helix
HHLPMJGF_00571 8.5e-54 S macrophage migration inhibitory factor
HHLPMJGF_00572 1.1e-50 yqiG C Oxidoreductase
HHLPMJGF_00573 7.8e-20 yqiG C Oxidoreductase
HHLPMJGF_00574 3.7e-91 yqiG C Oxidoreductase
HHLPMJGF_00576 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00578 9.6e-247 M Glycosyl transferase family group 2
HHLPMJGF_00579 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HHLPMJGF_00580 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHLPMJGF_00581 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHLPMJGF_00582 8.2e-37
HHLPMJGF_00583 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00584 1.3e-08
HHLPMJGF_00585 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHLPMJGF_00586 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHLPMJGF_00587 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHLPMJGF_00588 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHLPMJGF_00589 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HHLPMJGF_00590 7.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHLPMJGF_00591 7.3e-88
HHLPMJGF_00593 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHLPMJGF_00594 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HHLPMJGF_00595 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHLPMJGF_00596 1.3e-35 ynzC S UPF0291 protein
HHLPMJGF_00597 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HHLPMJGF_00598 4.6e-117 plsC 2.3.1.51 I Acyltransferase
HHLPMJGF_00599 3.2e-141 yabB 2.1.1.223 L Methyltransferase small domain
HHLPMJGF_00600 5.4e-49 yazA L GIY-YIG catalytic domain protein
HHLPMJGF_00601 4.4e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHLPMJGF_00602 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HHLPMJGF_00603 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHLPMJGF_00604 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HHLPMJGF_00605 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHLPMJGF_00606 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHLPMJGF_00607 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HHLPMJGF_00608 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HHLPMJGF_00609 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHLPMJGF_00610 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHLPMJGF_00611 2.3e-162
HHLPMJGF_00612 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HHLPMJGF_00613 2.8e-170 S AI-2E family transporter
HHLPMJGF_00614 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
HHLPMJGF_00615 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
HHLPMJGF_00616 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
HHLPMJGF_00617 4.8e-88 GM epimerase
HHLPMJGF_00618 1.7e-154 ypdB V (ABC) transporter
HHLPMJGF_00619 6.2e-241 yhdP S Transporter associated domain
HHLPMJGF_00620 9.9e-85 nrdI F Belongs to the NrdI family
HHLPMJGF_00621 9.3e-74 S 3-demethylubiquinone-9 3-methyltransferase
HHLPMJGF_00622 3.1e-193 yeaN P Transporter, major facilitator family protein
HHLPMJGF_00623 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHLPMJGF_00624 5.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHLPMJGF_00625 1.8e-38
HHLPMJGF_00626 0.0 lacS G Transporter
HHLPMJGF_00627 1.9e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
HHLPMJGF_00628 1.5e-80 uspA T universal stress protein
HHLPMJGF_00629 1.5e-80 K AsnC family
HHLPMJGF_00630 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHLPMJGF_00631 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHLPMJGF_00632 1.6e-105 ypsA S Belongs to the UPF0398 family
HHLPMJGF_00633 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHLPMJGF_00634 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HHLPMJGF_00635 2e-161 EG EamA-like transporter family
HHLPMJGF_00636 3e-125 dnaD L DnaD domain protein
HHLPMJGF_00637 2.9e-85 ypmB S Protein conserved in bacteria
HHLPMJGF_00638 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HHLPMJGF_00639 2e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HHLPMJGF_00640 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HHLPMJGF_00641 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HHLPMJGF_00642 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHLPMJGF_00643 3.8e-87 S Protein of unknown function (DUF1440)
HHLPMJGF_00644 0.0 rafA 3.2.1.22 G alpha-galactosidase
HHLPMJGF_00645 4.2e-189 galR K Periplasmic binding protein-like domain
HHLPMJGF_00646 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HHLPMJGF_00647 1.2e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHLPMJGF_00648 2.6e-124 lrgB M LrgB-like family
HHLPMJGF_00649 1.9e-66 lrgA S LrgA family
HHLPMJGF_00650 2.4e-130 lytT K response regulator receiver
HHLPMJGF_00651 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HHLPMJGF_00652 4e-148 f42a O Band 7 protein
HHLPMJGF_00653 3e-259 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HHLPMJGF_00654 2.2e-156 yitU 3.1.3.104 S hydrolase
HHLPMJGF_00655 9.2e-39 S Cytochrome B5
HHLPMJGF_00657 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HHLPMJGF_00658 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
HHLPMJGF_00659 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHLPMJGF_00660 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HHLPMJGF_00661 1.2e-10 S Protein of unknown function (DUF4044)
HHLPMJGF_00662 1.5e-53
HHLPMJGF_00663 3.1e-77 mraZ K Belongs to the MraZ family
HHLPMJGF_00664 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHLPMJGF_00665 2.6e-56 ftsL D Cell division protein FtsL
HHLPMJGF_00666 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HHLPMJGF_00667 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHLPMJGF_00668 2.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHLPMJGF_00669 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHLPMJGF_00670 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHLPMJGF_00671 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHLPMJGF_00672 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHLPMJGF_00673 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHLPMJGF_00674 3.2e-40 yggT S YGGT family
HHLPMJGF_00675 5.1e-142 ylmH S S4 domain protein
HHLPMJGF_00676 1.9e-42 divIVA D DivIVA domain protein
HHLPMJGF_00677 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHLPMJGF_00678 4.2e-32 cspA K Cold shock protein
HHLPMJGF_00679 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HHLPMJGF_00681 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHLPMJGF_00682 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
HHLPMJGF_00683 1.3e-57 XK27_04120 S Putative amino acid metabolism
HHLPMJGF_00684 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHLPMJGF_00685 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HHLPMJGF_00686 9e-119 S Repeat protein
HHLPMJGF_00687 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHLPMJGF_00688 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHLPMJGF_00689 3.7e-19
HHLPMJGF_00690 6.1e-261 dtpT U amino acid peptide transporter
HHLPMJGF_00691 6.9e-15 yjjH S Calcineurin-like phosphoesterase
HHLPMJGF_00692 1.8e-136 yjjH S Calcineurin-like phosphoesterase
HHLPMJGF_00695 5.5e-110
HHLPMJGF_00696 2.8e-252 EGP Major facilitator Superfamily
HHLPMJGF_00697 9.5e-300 aspT P Predicted Permease Membrane Region
HHLPMJGF_00698 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HHLPMJGF_00699 1.6e-126 gntR1 K UbiC transcription regulator-associated domain protein
HHLPMJGF_00700 6.5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHLPMJGF_00701 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHLPMJGF_00702 0.0 yhgF K Tex-like protein N-terminal domain protein
HHLPMJGF_00703 1.9e-85 ydcK S Belongs to the SprT family
HHLPMJGF_00705 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HHLPMJGF_00706 1.3e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HHLPMJGF_00707 0.0 S Bacterial membrane protein, YfhO
HHLPMJGF_00708 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHLPMJGF_00709 3.1e-169 I alpha/beta hydrolase fold
HHLPMJGF_00710 9.4e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HHLPMJGF_00711 2.4e-119 tcyB E ABC transporter
HHLPMJGF_00712 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHLPMJGF_00713 4.8e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HHLPMJGF_00714 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
HHLPMJGF_00715 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHLPMJGF_00716 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HHLPMJGF_00717 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HHLPMJGF_00718 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHLPMJGF_00719 5e-207 yacL S domain protein
HHLPMJGF_00720 1.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHLPMJGF_00721 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHLPMJGF_00722 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHLPMJGF_00723 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHLPMJGF_00724 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHLPMJGF_00725 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HHLPMJGF_00726 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHLPMJGF_00727 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHLPMJGF_00728 1.3e-226 aadAT EK Aminotransferase, class I
HHLPMJGF_00729 1.7e-78 I alpha/beta hydrolase fold
HHLPMJGF_00730 8.5e-20 K Helix-turn-helix XRE-family like proteins
HHLPMJGF_00731 1.1e-35 S Phage derived protein Gp49-like (DUF891)
HHLPMJGF_00733 2e-274 pipD E Dipeptidase
HHLPMJGF_00734 0.0 yjbQ P TrkA C-terminal domain protein
HHLPMJGF_00735 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HHLPMJGF_00736 1.7e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHLPMJGF_00737 1.9e-86
HHLPMJGF_00738 5.9e-114 L PFAM Integrase catalytic region
HHLPMJGF_00740 3e-13
HHLPMJGF_00741 6.9e-10
HHLPMJGF_00742 4.7e-63 L transposase and inactivated derivatives, IS30 family
HHLPMJGF_00743 4.7e-35
HHLPMJGF_00744 2.1e-100 K DNA-templated transcription, initiation
HHLPMJGF_00745 6.1e-29
HHLPMJGF_00746 2.1e-60 L PFAM transposase IS200-family protein
HHLPMJGF_00747 2.5e-230 L transposase, IS605 OrfB family
HHLPMJGF_00748 5.5e-280 O Arylsulfotransferase (ASST)
HHLPMJGF_00749 6.1e-54 K helix_turn_helix, mercury resistance
HHLPMJGF_00750 7.1e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHLPMJGF_00751 1.6e-197 EGP Major facilitator Superfamily
HHLPMJGF_00752 2.1e-88 ymdB S Macro domain protein
HHLPMJGF_00753 8.4e-111 K Helix-turn-helix domain
HHLPMJGF_00754 0.0 pepO 3.4.24.71 O Peptidase family M13
HHLPMJGF_00755 5.7e-46
HHLPMJGF_00756 7.1e-242 S Putative metallopeptidase domain
HHLPMJGF_00757 2e-203 3.1.3.1 S associated with various cellular activities
HHLPMJGF_00758 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HHLPMJGF_00759 7.8e-64 yeaO S Protein of unknown function, DUF488
HHLPMJGF_00761 5.4e-116 yrkL S Flavodoxin-like fold
HHLPMJGF_00762 9.5e-55
HHLPMJGF_00763 2e-15 S Domain of unknown function (DUF4767)
HHLPMJGF_00764 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHLPMJGF_00765 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHLPMJGF_00766 6.9e-49
HHLPMJGF_00768 7.6e-205 nrnB S DHHA1 domain
HHLPMJGF_00769 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
HHLPMJGF_00770 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
HHLPMJGF_00771 2e-106 NU mannosyl-glycoprotein
HHLPMJGF_00772 2.3e-142 S Putative ABC-transporter type IV
HHLPMJGF_00773 7.8e-272 S ABC transporter, ATP-binding protein
HHLPMJGF_00774 8.2e-48
HHLPMJGF_00775 3e-75
HHLPMJGF_00776 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHLPMJGF_00777 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HHLPMJGF_00778 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HHLPMJGF_00779 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHLPMJGF_00780 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHLPMJGF_00783 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHLPMJGF_00784 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
HHLPMJGF_00785 2.4e-223 mdtG EGP Major facilitator Superfamily
HHLPMJGF_00786 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHLPMJGF_00787 1.2e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HHLPMJGF_00788 3.9e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHLPMJGF_00789 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HHLPMJGF_00790 9.5e-220 lacS G Transporter
HHLPMJGF_00791 2.1e-107 lacS G Transporter
HHLPMJGF_00792 8.8e-187 lacR K Transcriptional regulator
HHLPMJGF_00793 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_00794 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
HHLPMJGF_00795 1.8e-267 frdC 1.3.5.4 C FAD binding domain
HHLPMJGF_00796 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHLPMJGF_00797 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HHLPMJGF_00798 1.9e-161 mleR K LysR family
HHLPMJGF_00799 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHLPMJGF_00800 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HHLPMJGF_00801 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
HHLPMJGF_00802 1.6e-168 L transposase, IS605 OrfB family
HHLPMJGF_00803 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
HHLPMJGF_00804 1.9e-25
HHLPMJGF_00805 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HHLPMJGF_00806 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00807 1.2e-230 L Integrase core domain
HHLPMJGF_00808 5e-241 M NlpC/P60 family
HHLPMJGF_00809 3.1e-245 M NlpC/P60 family
HHLPMJGF_00810 1.2e-230 L Integrase core domain
HHLPMJGF_00811 1.1e-189 L Transposase
HHLPMJGF_00812 9e-283 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HHLPMJGF_00813 9.7e-62 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HHLPMJGF_00814 1.1e-117 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HHLPMJGF_00815 2.7e-296 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HHLPMJGF_00816 9.2e-71 S GyrI-like small molecule binding domain
HHLPMJGF_00817 9.2e-38 S GyrI-like small molecule binding domain
HHLPMJGF_00818 5e-122 yhiD S MgtC family
HHLPMJGF_00819 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHLPMJGF_00820 1.4e-114 V Beta-lactamase
HHLPMJGF_00821 1.1e-64 V Beta-lactamase
HHLPMJGF_00823 8.6e-59 lsa S ABC transporter
HHLPMJGF_00824 1.2e-82 lsa S ABC transporter
HHLPMJGF_00825 1.8e-81 lsa S ABC transporter
HHLPMJGF_00826 3.5e-134 I alpha/beta hydrolase fold
HHLPMJGF_00827 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
HHLPMJGF_00828 1.4e-209 G Belongs to the glycosyl hydrolase family 6
HHLPMJGF_00829 1.2e-22 G Belongs to the glycosyl hydrolase family 6
HHLPMJGF_00830 1.3e-96 S NADPH-dependent FMN reductase
HHLPMJGF_00831 7.4e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HHLPMJGF_00832 2.6e-68 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HHLPMJGF_00833 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00834 1.8e-43
HHLPMJGF_00835 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
HHLPMJGF_00836 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HHLPMJGF_00837 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHLPMJGF_00838 4e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HHLPMJGF_00839 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HHLPMJGF_00840 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHLPMJGF_00841 1.6e-67
HHLPMJGF_00842 1.1e-150 lysA2 M Glycosyl hydrolases family 25
HHLPMJGF_00843 2.8e-33 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HHLPMJGF_00850 6.9e-40 GT2,GT4 LM gp58-like protein
HHLPMJGF_00851 1.1e-145 ydhO 3.4.14.13 M Prophage endopeptidase tail
HHLPMJGF_00852 8.9e-79 S Phage tail protein
HHLPMJGF_00853 1.1e-146 M by MetaGeneAnnotator
HHLPMJGF_00854 4.9e-13 S Phage tail assembly chaperone proteins, TAC
HHLPMJGF_00855 5.8e-116 S Phage tail tube protein
HHLPMJGF_00856 5.8e-38 S Protein of unknown function (DUF806)
HHLPMJGF_00857 1.9e-37 S Bacteriophage HK97-gp10, putative tail-component
HHLPMJGF_00858 4.8e-39 S Phage head-tail joining protein
HHLPMJGF_00859 1.8e-36 S Phage gp6-like head-tail connector protein
HHLPMJGF_00860 2.4e-151 S Phage capsid family
HHLPMJGF_00861 1.5e-116 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HHLPMJGF_00862 3.7e-197 S Phage portal protein
HHLPMJGF_00863 3e-158 S Phage Terminase
HHLPMJGF_00864 4.4e-94 S Phage Terminase
HHLPMJGF_00865 8e-61 S regulation of transcription, DNA-dependent
HHLPMJGF_00866 9.3e-56 L Phage terminase, small subunit
HHLPMJGF_00867 6.2e-56 L HNH nucleases
HHLPMJGF_00868 2.1e-09
HHLPMJGF_00873 3.5e-32
HHLPMJGF_00875 6.7e-64 rusA L Endodeoxyribonuclease RusA
HHLPMJGF_00876 1.8e-12
HHLPMJGF_00877 5.6e-52 S ORF6C domain
HHLPMJGF_00879 4.1e-57 dnaC 3.4.21.53 L IstB-like ATP binding protein
HHLPMJGF_00880 4.1e-69 ybl78 L DnaD domain protein
HHLPMJGF_00881 1.5e-14 L Single-strand binding protein family
HHLPMJGF_00882 7.7e-51 S ERF superfamily
HHLPMJGF_00886 4e-27 S Domain of unknown function (DUF771)
HHLPMJGF_00887 2.8e-92 K BRO family, N-terminal domain
HHLPMJGF_00889 4.6e-41 xre K Helix-turn-helix XRE-family like proteins
HHLPMJGF_00890 7.7e-20 E Zn peptidase
HHLPMJGF_00891 6.3e-17
HHLPMJGF_00892 6.9e-85 J Domain of unknown function (DUF4041)
HHLPMJGF_00893 2.2e-103 L Belongs to the 'phage' integrase family
HHLPMJGF_00895 1.9e-43
HHLPMJGF_00896 4.5e-112 S CAAX protease self-immunity
HHLPMJGF_00897 2.1e-32
HHLPMJGF_00898 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHLPMJGF_00899 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HHLPMJGF_00900 3.2e-112
HHLPMJGF_00901 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HHLPMJGF_00902 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHLPMJGF_00903 1.2e-85 uspA T Belongs to the universal stress protein A family
HHLPMJGF_00904 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
HHLPMJGF_00905 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHLPMJGF_00906 4.1e-303 ytgP S Polysaccharide biosynthesis protein
HHLPMJGF_00907 4.9e-41
HHLPMJGF_00908 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHLPMJGF_00909 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHLPMJGF_00910 9.6e-92 tag 3.2.2.20 L glycosylase
HHLPMJGF_00911 1.5e-253 EGP Major facilitator Superfamily
HHLPMJGF_00912 4.3e-85 perR P Belongs to the Fur family
HHLPMJGF_00913 4.8e-233 cycA E Amino acid permease
HHLPMJGF_00914 2.8e-102 V VanZ like family
HHLPMJGF_00915 1e-23
HHLPMJGF_00916 7.7e-86 S Short repeat of unknown function (DUF308)
HHLPMJGF_00917 2.9e-78 S Psort location Cytoplasmic, score
HHLPMJGF_00918 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HHLPMJGF_00919 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HHLPMJGF_00920 2.4e-153 yeaE S Aldo keto
HHLPMJGF_00921 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
HHLPMJGF_00922 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HHLPMJGF_00923 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
HHLPMJGF_00924 2.3e-93 lytE M LysM domain protein
HHLPMJGF_00925 0.0 oppD EP Psort location Cytoplasmic, score
HHLPMJGF_00926 2.6e-80 lytE M LysM domain protein
HHLPMJGF_00927 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
HHLPMJGF_00928 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHLPMJGF_00929 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HHLPMJGF_00932 5.1e-22 M LPXTG-motif cell wall anchor domain protein
HHLPMJGF_00933 1.1e-34 M LPXTG-motif cell wall anchor domain protein
HHLPMJGF_00934 0.0 M LPXTG-motif cell wall anchor domain protein
HHLPMJGF_00935 1.3e-180 M LPXTG-motif cell wall anchor domain protein
HHLPMJGF_00936 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HHLPMJGF_00937 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
HHLPMJGF_00938 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HHLPMJGF_00939 1.3e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HHLPMJGF_00940 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_00941 3.3e-40
HHLPMJGF_00943 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHLPMJGF_00944 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHLPMJGF_00945 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HHLPMJGF_00946 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHLPMJGF_00947 3.5e-40 yheA S Belongs to the UPF0342 family
HHLPMJGF_00948 1.8e-220 yhaO L Ser Thr phosphatase family protein
HHLPMJGF_00949 0.0 L AAA domain
HHLPMJGF_00950 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHLPMJGF_00952 1.2e-76 hit FG histidine triad
HHLPMJGF_00953 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HHLPMJGF_00954 5.1e-218 ecsB U ABC transporter
HHLPMJGF_00955 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHLPMJGF_00956 7.7e-27 S YSIRK type signal peptide
HHLPMJGF_00957 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HHLPMJGF_00958 9.5e-256 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HHLPMJGF_00959 1.1e-136 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HHLPMJGF_00960 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HHLPMJGF_00961 8.8e-184 iolS C Aldo keto reductase
HHLPMJGF_00962 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
HHLPMJGF_00963 1.4e-56 ytzB S Small secreted protein
HHLPMJGF_00964 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHLPMJGF_00965 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHLPMJGF_00966 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HHLPMJGF_00967 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HHLPMJGF_00968 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HHLPMJGF_00969 1.9e-119 ybhL S Belongs to the BI1 family
HHLPMJGF_00970 4.1e-116 yoaK S Protein of unknown function (DUF1275)
HHLPMJGF_00971 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHLPMJGF_00972 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHLPMJGF_00973 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHLPMJGF_00974 5.6e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHLPMJGF_00975 1.4e-203 dnaB L replication initiation and membrane attachment
HHLPMJGF_00976 1.1e-170 dnaI L Primosomal protein DnaI
HHLPMJGF_00977 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHLPMJGF_00978 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HHLPMJGF_00979 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHLPMJGF_00980 1.8e-95 yqeG S HAD phosphatase, family IIIA
HHLPMJGF_00981 2.4e-217 yqeH S Ribosome biogenesis GTPase YqeH
HHLPMJGF_00982 1.9e-47 yhbY J RNA-binding protein
HHLPMJGF_00983 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHLPMJGF_00984 3.9e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HHLPMJGF_00985 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHLPMJGF_00986 1.7e-139 yqeM Q Methyltransferase
HHLPMJGF_00987 2.1e-213 ylbM S Belongs to the UPF0348 family
HHLPMJGF_00988 2.9e-99 yceD S Uncharacterized ACR, COG1399
HHLPMJGF_00989 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HHLPMJGF_00990 1.5e-121 K response regulator
HHLPMJGF_00991 4.1e-278 arlS 2.7.13.3 T Histidine kinase
HHLPMJGF_00992 7.4e-267 yjeM E Amino Acid
HHLPMJGF_00993 4.4e-231 V MatE
HHLPMJGF_00994 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HHLPMJGF_00995 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHLPMJGF_00996 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HHLPMJGF_00997 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHLPMJGF_00998 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHLPMJGF_00999 2e-58 yodB K Transcriptional regulator, HxlR family
HHLPMJGF_01000 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHLPMJGF_01001 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHLPMJGF_01002 5.6e-115 rlpA M PFAM NLP P60 protein
HHLPMJGF_01003 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HHLPMJGF_01004 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHLPMJGF_01005 1.8e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HHLPMJGF_01006 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHLPMJGF_01007 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHLPMJGF_01008 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHLPMJGF_01009 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHLPMJGF_01010 3.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHLPMJGF_01011 9.8e-67 yabR J RNA binding
HHLPMJGF_01012 3.3e-56 divIC D Septum formation initiator
HHLPMJGF_01013 8.1e-39 yabO J S4 domain protein
HHLPMJGF_01014 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHLPMJGF_01015 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHLPMJGF_01016 4e-113 S (CBS) domain
HHLPMJGF_01017 3.1e-147 tesE Q hydratase
HHLPMJGF_01018 4.7e-243 codA 3.5.4.1 F cytosine deaminase
HHLPMJGF_01019 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HHLPMJGF_01020 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HHLPMJGF_01021 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHLPMJGF_01022 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHLPMJGF_01024 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHLPMJGF_01025 2.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
HHLPMJGF_01026 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHLPMJGF_01027 8.9e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHLPMJGF_01028 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
HHLPMJGF_01029 4.2e-140 sprD D Domain of Unknown Function (DUF1542)
HHLPMJGF_01030 1.1e-126 L PFAM Integrase catalytic region
HHLPMJGF_01031 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHLPMJGF_01032 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHLPMJGF_01033 2.9e-157 htpX O Belongs to the peptidase M48B family
HHLPMJGF_01034 7e-93 lemA S LemA family
HHLPMJGF_01035 5.7e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHLPMJGF_01036 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HHLPMJGF_01037 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HHLPMJGF_01038 3.1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHLPMJGF_01039 9.5e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HHLPMJGF_01040 5.1e-125 srtA 3.4.22.70 M sortase family
HHLPMJGF_01041 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HHLPMJGF_01042 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHLPMJGF_01043 4.6e-41 rpmE2 J Ribosomal protein L31
HHLPMJGF_01044 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHLPMJGF_01045 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHLPMJGF_01046 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHLPMJGF_01047 3e-66 ywiB S Domain of unknown function (DUF1934)
HHLPMJGF_01048 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HHLPMJGF_01049 5e-270 ywfO S HD domain protein
HHLPMJGF_01050 2.5e-147 yxeH S hydrolase
HHLPMJGF_01051 1.6e-188 pgaC GT2 M Glycosyl transferase
HHLPMJGF_01052 5.2e-84
HHLPMJGF_01053 1.2e-203 2.7.7.65 T GGDEF domain
HHLPMJGF_01054 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HHLPMJGF_01055 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HHLPMJGF_01056 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
HHLPMJGF_01057 6.6e-262 S Putative peptidoglycan binding domain
HHLPMJGF_01059 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHLPMJGF_01060 4.7e-177 ABC-SBP S ABC transporter
HHLPMJGF_01061 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HHLPMJGF_01062 3.3e-215 htrA 3.4.21.107 O serine protease
HHLPMJGF_01063 5e-153 vicX 3.1.26.11 S domain protein
HHLPMJGF_01064 2.7e-149 yycI S YycH protein
HHLPMJGF_01065 2.1e-246 yycH S YycH protein
HHLPMJGF_01066 0.0 vicK 2.7.13.3 T Histidine kinase
HHLPMJGF_01067 6.8e-130 K response regulator
HHLPMJGF_01069 8.1e-310 lmrA 3.6.3.44 V ABC transporter
HHLPMJGF_01070 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
HHLPMJGF_01072 7.2e-101
HHLPMJGF_01074 1.4e-124 yciB M ErfK YbiS YcfS YnhG
HHLPMJGF_01075 6e-15
HHLPMJGF_01076 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HHLPMJGF_01077 6.7e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HHLPMJGF_01078 6.2e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HHLPMJGF_01079 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHLPMJGF_01080 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHLPMJGF_01081 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHLPMJGF_01082 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHLPMJGF_01083 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HHLPMJGF_01084 7.4e-134 K LysR substrate binding domain
HHLPMJGF_01085 1.7e-47 L PFAM transposase IS200-family protein
HHLPMJGF_01086 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
HHLPMJGF_01087 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
HHLPMJGF_01088 2.6e-155 glcU U sugar transport
HHLPMJGF_01089 3.4e-272 yclK 2.7.13.3 T Histidine kinase
HHLPMJGF_01090 1.5e-132 K response regulator
HHLPMJGF_01092 2.8e-79 lytE M Lysin motif
HHLPMJGF_01093 5.7e-149 XK27_02985 S Cof-like hydrolase
HHLPMJGF_01094 2.3e-81 K Transcriptional regulator
HHLPMJGF_01095 0.0 oatA I Acyltransferase
HHLPMJGF_01096 8.7e-53
HHLPMJGF_01097 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHLPMJGF_01098 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHLPMJGF_01099 2e-126 ybbR S YbbR-like protein
HHLPMJGF_01100 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHLPMJGF_01101 4.8e-249 fucP G Major Facilitator Superfamily
HHLPMJGF_01102 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HHLPMJGF_01103 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHLPMJGF_01104 8e-168 murB 1.3.1.98 M Cell wall formation
HHLPMJGF_01105 2e-180 galR K Transcriptional regulator
HHLPMJGF_01106 2.2e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HHLPMJGF_01107 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHLPMJGF_01108 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HHLPMJGF_01109 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HHLPMJGF_01110 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
HHLPMJGF_01111 9.1e-36
HHLPMJGF_01112 2.6e-52
HHLPMJGF_01113 2.3e-204
HHLPMJGF_01114 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHLPMJGF_01115 8.9e-136 pnuC H nicotinamide mononucleotide transporter
HHLPMJGF_01116 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
HHLPMJGF_01117 4.9e-125 K response regulator
HHLPMJGF_01118 4.5e-180 T PhoQ Sensor
HHLPMJGF_01119 2.6e-135 macB2 V ABC transporter, ATP-binding protein
HHLPMJGF_01120 2.1e-40 ysaB V FtsX-like permease family
HHLPMJGF_01121 3.9e-81 ysaB V FtsX-like permease family
HHLPMJGF_01122 1.4e-195 ysaB V FtsX-like permease family
HHLPMJGF_01123 2.7e-49
HHLPMJGF_01124 1.6e-67 yqkB S Belongs to the HesB IscA family
HHLPMJGF_01125 5.9e-114 L PFAM Integrase catalytic region
HHLPMJGF_01126 2.2e-72
HHLPMJGF_01127 4.8e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HHLPMJGF_01128 6.7e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HHLPMJGF_01129 2.4e-277 M domain protein
HHLPMJGF_01130 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HHLPMJGF_01131 3.2e-264 G Major Facilitator
HHLPMJGF_01132 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HHLPMJGF_01133 6.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHLPMJGF_01134 1e-259 G Major Facilitator
HHLPMJGF_01135 1.2e-180 K Transcriptional regulator, LacI family
HHLPMJGF_01136 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHLPMJGF_01138 1.2e-100 nqr 1.5.1.36 S reductase
HHLPMJGF_01139 6.1e-198 XK27_09615 S reductase
HHLPMJGF_01140 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHLPMJGF_01142 1.5e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HHLPMJGF_01143 9.3e-130 IQ Dehydrogenase reductase
HHLPMJGF_01144 9.2e-36
HHLPMJGF_01145 4.8e-114 ywnB S NAD(P)H-binding
HHLPMJGF_01146 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
HHLPMJGF_01147 1.2e-255 nhaC C Na H antiporter NhaC
HHLPMJGF_01148 3.4e-155 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHLPMJGF_01149 2.9e-165 L Transposase
HHLPMJGF_01150 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHLPMJGF_01151 5.5e-126 S Alpha beta hydrolase
HHLPMJGF_01152 1.7e-207 gldA 1.1.1.6 C dehydrogenase
HHLPMJGF_01153 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHLPMJGF_01154 1.3e-41
HHLPMJGF_01155 4e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
HHLPMJGF_01156 1.4e-284 S C4-dicarboxylate anaerobic carrier
HHLPMJGF_01157 4.5e-250 nhaC C Na H antiporter NhaC
HHLPMJGF_01158 1.6e-241 pbuX F xanthine permease
HHLPMJGF_01159 1.4e-283 pipD E Dipeptidase
HHLPMJGF_01160 1.6e-305 L Transposase
HHLPMJGF_01161 2.2e-168 corA P CorA-like Mg2+ transporter protein
HHLPMJGF_01162 4.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHLPMJGF_01163 2.3e-131 terC P membrane
HHLPMJGF_01164 2.1e-54 trxA O Belongs to the thioredoxin family
HHLPMJGF_01165 1.6e-236 mepA V MATE efflux family protein
HHLPMJGF_01166 5.5e-55 M Leucine-rich repeat (LRR) protein
HHLPMJGF_01167 6.8e-56 K Transcriptional regulator, ArsR family
HHLPMJGF_01168 1.2e-92 P Cadmium resistance transporter
HHLPMJGF_01169 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
HHLPMJGF_01170 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HHLPMJGF_01171 2.2e-182 ABC-SBP S ABC transporter
HHLPMJGF_01172 1.3e-73 M PFAM NLP P60 protein
HHLPMJGF_01173 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_01174 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
HHLPMJGF_01175 4.4e-76 S PAS domain
HHLPMJGF_01176 2.6e-86 K Acetyltransferase (GNAT) domain
HHLPMJGF_01177 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HHLPMJGF_01178 7.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HHLPMJGF_01179 2e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHLPMJGF_01180 6.3e-105 yxjI
HHLPMJGF_01181 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHLPMJGF_01182 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHLPMJGF_01183 2.8e-145 est 3.1.1.1 S Serine aminopeptidase, S33
HHLPMJGF_01184 1.8e-34 secG U Preprotein translocase
HHLPMJGF_01185 4e-292 clcA P chloride
HHLPMJGF_01186 7.1e-248 yifK E Amino acid permease
HHLPMJGF_01187 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHLPMJGF_01188 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHLPMJGF_01189 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HHLPMJGF_01190 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHLPMJGF_01192 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHLPMJGF_01193 8.8e-15
HHLPMJGF_01195 4e-170 whiA K May be required for sporulation
HHLPMJGF_01196 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HHLPMJGF_01197 1.1e-161 rapZ S Displays ATPase and GTPase activities
HHLPMJGF_01198 5.4e-245 steT E amino acid
HHLPMJGF_01199 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHLPMJGF_01200 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHLPMJGF_01201 1.5e-13
HHLPMJGF_01202 2.3e-116 yfbR S HD containing hydrolase-like enzyme
HHLPMJGF_01203 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HHLPMJGF_01204 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HHLPMJGF_01205 3.5e-103 aatB ET PFAM extracellular solute-binding protein, family 3
HHLPMJGF_01206 5.9e-32 aatB ET PFAM extracellular solute-binding protein, family 3
HHLPMJGF_01207 3.8e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HHLPMJGF_01208 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHLPMJGF_01209 3.5e-163 lutA C Cysteine-rich domain
HHLPMJGF_01210 9.8e-288 lutB C 4Fe-4S dicluster domain
HHLPMJGF_01211 3.4e-115 yrjD S LUD domain
HHLPMJGF_01212 4.8e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHLPMJGF_01213 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HHLPMJGF_01214 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHLPMJGF_01215 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHLPMJGF_01216 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HHLPMJGF_01217 3.1e-32 KT PspC domain protein
HHLPMJGF_01218 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHLPMJGF_01219 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHLPMJGF_01220 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHLPMJGF_01221 1.3e-114 comFC S Competence protein
HHLPMJGF_01222 1.4e-256 comFA L Helicase C-terminal domain protein
HHLPMJGF_01223 2.9e-111 yvyE 3.4.13.9 S YigZ family
HHLPMJGF_01224 5.4e-235 EGP Major facilitator Superfamily
HHLPMJGF_01225 7.4e-68 rmaI K Transcriptional regulator
HHLPMJGF_01226 9.2e-40
HHLPMJGF_01227 0.0 ydaO E amino acid
HHLPMJGF_01228 4.3e-305 ybeC E amino acid
HHLPMJGF_01229 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
HHLPMJGF_01230 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHLPMJGF_01231 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHLPMJGF_01233 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHLPMJGF_01234 0.0 uup S ABC transporter, ATP-binding protein
HHLPMJGF_01235 5.8e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHLPMJGF_01236 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
HHLPMJGF_01237 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HHLPMJGF_01238 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHLPMJGF_01239 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHLPMJGF_01240 6.8e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHLPMJGF_01241 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHLPMJGF_01242 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HHLPMJGF_01243 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HHLPMJGF_01244 5.9e-114 L PFAM Integrase catalytic region
HHLPMJGF_01245 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_01246 3e-50 S CRISPR-associated protein (Cas_Csn2)
HHLPMJGF_01247 1.7e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHLPMJGF_01248 9.8e-113 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHLPMJGF_01249 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HHLPMJGF_01250 3.3e-83
HHLPMJGF_01251 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HHLPMJGF_01252 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
HHLPMJGF_01253 2.9e-34
HHLPMJGF_01254 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHLPMJGF_01255 9.9e-261 yfnA E amino acid
HHLPMJGF_01256 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HHLPMJGF_01257 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHLPMJGF_01258 2e-39 ylqC S Belongs to the UPF0109 family
HHLPMJGF_01259 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HHLPMJGF_01260 5.1e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHLPMJGF_01261 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHLPMJGF_01262 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHLPMJGF_01263 0.0 smc D Required for chromosome condensation and partitioning
HHLPMJGF_01264 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHLPMJGF_01265 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHLPMJGF_01266 4.7e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHLPMJGF_01267 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHLPMJGF_01268 0.0 yloV S DAK2 domain fusion protein YloV
HHLPMJGF_01269 4.7e-58 asp S Asp23 family, cell envelope-related function
HHLPMJGF_01270 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HHLPMJGF_01271 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HHLPMJGF_01272 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HHLPMJGF_01273 7.5e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHLPMJGF_01274 0.0 KLT serine threonine protein kinase
HHLPMJGF_01275 2.9e-131 stp 3.1.3.16 T phosphatase
HHLPMJGF_01276 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHLPMJGF_01277 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHLPMJGF_01278 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHLPMJGF_01279 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHLPMJGF_01280 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHLPMJGF_01281 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HHLPMJGF_01282 1.7e-54
HHLPMJGF_01283 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
HHLPMJGF_01284 3.3e-77 argR K Regulates arginine biosynthesis genes
HHLPMJGF_01285 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HHLPMJGF_01286 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHLPMJGF_01287 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHLPMJGF_01288 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHLPMJGF_01289 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHLPMJGF_01290 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHLPMJGF_01291 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HHLPMJGF_01292 1.7e-114 J 2'-5' RNA ligase superfamily
HHLPMJGF_01293 3.9e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HHLPMJGF_01294 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHLPMJGF_01295 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_01300 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HHLPMJGF_01301 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HHLPMJGF_01302 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHLPMJGF_01303 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HHLPMJGF_01304 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHLPMJGF_01305 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHLPMJGF_01306 2.6e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHLPMJGF_01307 4.2e-130 IQ reductase
HHLPMJGF_01308 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HHLPMJGF_01309 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHLPMJGF_01310 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHLPMJGF_01311 4.2e-77 marR K Transcriptional regulator, MarR family
HHLPMJGF_01312 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHLPMJGF_01314 9.6e-200 xerS L Belongs to the 'phage' integrase family
HHLPMJGF_01315 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_01316 4.2e-74 osmC O OsmC-like protein
HHLPMJGF_01317 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHLPMJGF_01318 6.1e-216 patA 2.6.1.1 E Aminotransferase
HHLPMJGF_01319 7.8e-32
HHLPMJGF_01320 0.0 clpL O associated with various cellular activities
HHLPMJGF_01322 9.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
HHLPMJGF_01323 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHLPMJGF_01324 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HHLPMJGF_01325 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HHLPMJGF_01326 1.5e-172 malR K Transcriptional regulator, LacI family
HHLPMJGF_01327 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
HHLPMJGF_01328 1.1e-256 malT G Major Facilitator
HHLPMJGF_01329 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HHLPMJGF_01330 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HHLPMJGF_01331 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
HHLPMJGF_01332 3.3e-118 K response regulator
HHLPMJGF_01333 5.3e-226 sptS 2.7.13.3 T Histidine kinase
HHLPMJGF_01334 2.5e-209 yfeO P Voltage gated chloride channel
HHLPMJGF_01335 8.1e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HHLPMJGF_01336 6.6e-136 puuD S peptidase C26
HHLPMJGF_01337 3.8e-167 yvgN C Aldo keto reductase
HHLPMJGF_01338 1.8e-47 1.14.12.17 S Cupin 2, conserved barrel domain protein
HHLPMJGF_01339 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HHLPMJGF_01340 5.6e-86 hmpT S ECF-type riboflavin transporter, S component
HHLPMJGF_01341 4.2e-261 nox C NADH oxidase
HHLPMJGF_01342 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHLPMJGF_01343 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHLPMJGF_01344 1.5e-85
HHLPMJGF_01345 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHLPMJGF_01347 4.3e-13 K Transcriptional regulator, TetR family
HHLPMJGF_01348 6.2e-76 K Transcriptional regulator, TetR family
HHLPMJGF_01349 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_01350 4.9e-73 merR K MerR HTH family regulatory protein
HHLPMJGF_01351 2.7e-269 lmrB EGP Major facilitator Superfamily
HHLPMJGF_01352 9.5e-119 S Domain of unknown function (DUF4811)
HHLPMJGF_01353 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HHLPMJGF_01355 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHLPMJGF_01356 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HHLPMJGF_01357 3.4e-188 I Alpha beta
HHLPMJGF_01358 8.5e-282 emrY EGP Major facilitator Superfamily
HHLPMJGF_01359 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
HHLPMJGF_01360 2e-250 yjjP S Putative threonine/serine exporter
HHLPMJGF_01361 1e-159 mleR K LysR family
HHLPMJGF_01362 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHLPMJGF_01363 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_01364 1.2e-06 D nuclear chromosome segregation
HHLPMJGF_01365 0.0 snf 2.7.11.1 KL domain protein
HHLPMJGF_01366 2.4e-144 ywqE 3.1.3.48 GM PHP domain protein
HHLPMJGF_01367 3.7e-176 M Glycosyl hydrolases family 25
HHLPMJGF_01368 2.2e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HHLPMJGF_01369 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HHLPMJGF_01370 2.4e-92 L nuclease
HHLPMJGF_01371 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHLPMJGF_01372 3.3e-71
HHLPMJGF_01373 7e-101 fic D Fic/DOC family
HHLPMJGF_01374 2.6e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHLPMJGF_01375 7e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HHLPMJGF_01376 1e-31
HHLPMJGF_01377 5.8e-43
HHLPMJGF_01378 1.8e-99
HHLPMJGF_01379 7.1e-25
HHLPMJGF_01380 1.9e-40
HHLPMJGF_01381 2.2e-243 ydaM M Glycosyl transferase
HHLPMJGF_01382 1.4e-217 G Glycosyl hydrolases family 8
HHLPMJGF_01383 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HHLPMJGF_01384 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HHLPMJGF_01385 1.7e-238 ktrB P Potassium uptake protein
HHLPMJGF_01386 1.4e-116 ktrA P domain protein
HHLPMJGF_01387 1.2e-81 Q Methyltransferase
HHLPMJGF_01388 3.1e-229 mntH P H( )-stimulated, divalent metal cation uptake system
HHLPMJGF_01389 2.9e-31 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HHLPMJGF_01390 4.2e-32 feoA P FeoA domain
HHLPMJGF_01391 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HHLPMJGF_01392 5.5e-19
HHLPMJGF_01393 4.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HHLPMJGF_01394 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HHLPMJGF_01395 3.5e-64 ydiI Q Thioesterase superfamily
HHLPMJGF_01396 5.4e-109 yvrI K sigma factor activity
HHLPMJGF_01397 5e-202 G Transporter, major facilitator family protein
HHLPMJGF_01398 0.0 S Bacterial membrane protein YfhO
HHLPMJGF_01399 2.4e-101 T Ion transport 2 domain protein
HHLPMJGF_01400 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HHLPMJGF_01401 2.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HHLPMJGF_01402 1.2e-95 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HHLPMJGF_01403 1.2e-194 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHLPMJGF_01404 1.5e-180 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HHLPMJGF_01405 2.5e-230 L transposase, IS605 OrfB family
HHLPMJGF_01406 2.1e-60 L PFAM transposase IS200-family protein
HHLPMJGF_01409 2.3e-78 O Bacterial dnaA protein
HHLPMJGF_01410 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HHLPMJGF_01411 3.3e-46 gcvH E glycine cleavage
HHLPMJGF_01412 1.6e-219 rodA D Belongs to the SEDS family
HHLPMJGF_01413 1e-31 S Protein of unknown function (DUF2969)
HHLPMJGF_01414 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HHLPMJGF_01415 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHLPMJGF_01416 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HHLPMJGF_01417 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HHLPMJGF_01418 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHLPMJGF_01419 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHLPMJGF_01420 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHLPMJGF_01421 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHLPMJGF_01422 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHLPMJGF_01423 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHLPMJGF_01424 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HHLPMJGF_01425 5e-232 pyrP F Permease
HHLPMJGF_01426 6.3e-129 yibF S overlaps another CDS with the same product name
HHLPMJGF_01427 9.9e-192 yibE S overlaps another CDS with the same product name
HHLPMJGF_01428 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHLPMJGF_01429 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHLPMJGF_01430 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHLPMJGF_01431 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHLPMJGF_01432 1.7e-162 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHLPMJGF_01433 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHLPMJGF_01434 6e-108 tdk 2.7.1.21 F thymidine kinase
HHLPMJGF_01435 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HHLPMJGF_01436 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HHLPMJGF_01437 2.7e-223 arcD U Amino acid permease
HHLPMJGF_01438 2e-261 E Arginine ornithine antiporter
HHLPMJGF_01439 4.7e-79 argR K Regulates arginine biosynthesis genes
HHLPMJGF_01440 4.1e-239 arcA 3.5.3.6 E Arginine
HHLPMJGF_01441 3.9e-187 ampC V Beta-lactamase
HHLPMJGF_01442 1.9e-32
HHLPMJGF_01443 0.0 M domain protein
HHLPMJGF_01444 5.9e-91
HHLPMJGF_01446 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HHLPMJGF_01447 1.3e-61 asp S Asp23 family, cell envelope-related function
HHLPMJGF_01448 2.1e-25
HHLPMJGF_01449 3.2e-95
HHLPMJGF_01450 2e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HHLPMJGF_01451 9.9e-183 K Transcriptional regulator, LacI family
HHLPMJGF_01452 3.2e-229 gntT EG Gluconate
HHLPMJGF_01453 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HHLPMJGF_01454 2.9e-96 K Acetyltransferase (GNAT) domain
HHLPMJGF_01455 5.4e-47
HHLPMJGF_01456 0.0 nylA 3.5.1.4 J Belongs to the amidase family
HHLPMJGF_01457 2.2e-44
HHLPMJGF_01458 2.8e-58 yhaI S Protein of unknown function (DUF805)
HHLPMJGF_01459 6.2e-140 IQ reductase
HHLPMJGF_01460 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HHLPMJGF_01461 8.8e-173 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HHLPMJGF_01462 1e-293 hsdM 2.1.1.72 V type I restriction-modification system
HHLPMJGF_01463 3.1e-17 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HHLPMJGF_01464 9.5e-112 S Membrane
HHLPMJGF_01465 1.2e-64 O Zinc-dependent metalloprotease
HHLPMJGF_01466 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHLPMJGF_01467 4.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HHLPMJGF_01469 1.1e-17 NU Mycoplasma protein of unknown function, DUF285
HHLPMJGF_01470 4.3e-87 UW LPXTG-motif cell wall anchor domain protein
HHLPMJGF_01471 0.0 UW LPXTG-motif cell wall anchor domain protein
HHLPMJGF_01472 0.0 S Peptidase, M23
HHLPMJGF_01473 4.4e-140 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HHLPMJGF_01474 9.7e-31
HHLPMJGF_01475 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHLPMJGF_01476 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHLPMJGF_01477 1e-110 K Bacterial regulatory proteins, tetR family
HHLPMJGF_01478 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHLPMJGF_01479 4.4e-77 ctsR K Belongs to the CtsR family
HHLPMJGF_01480 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HHLPMJGF_01481 1.3e-16 S Hydrolases of the alpha beta superfamily
HHLPMJGF_01482 5.3e-130 S Hydrolases of the alpha beta superfamily
HHLPMJGF_01488 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HHLPMJGF_01489 1.5e-275 lysP E amino acid
HHLPMJGF_01490 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
HHLPMJGF_01491 2.7e-120 lssY 3.6.1.27 I phosphatase
HHLPMJGF_01492 6.7e-81 S Threonine/Serine exporter, ThrE
HHLPMJGF_01493 3.6e-129 thrE S Putative threonine/serine exporter
HHLPMJGF_01494 3.5e-31 cspC K Cold shock protein
HHLPMJGF_01495 1.1e-124 sirR K iron dependent repressor
HHLPMJGF_01496 1.2e-163 czcD P cation diffusion facilitator family transporter
HHLPMJGF_01497 1.6e-115 S membrane
HHLPMJGF_01498 8.4e-109 S VIT family
HHLPMJGF_01499 5.5e-83 usp1 T Belongs to the universal stress protein A family
HHLPMJGF_01500 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHLPMJGF_01501 5.7e-152 glnH ET ABC transporter
HHLPMJGF_01502 4.2e-110 gluC P ABC transporter permease
HHLPMJGF_01503 1.4e-108 glnP P ABC transporter permease
HHLPMJGF_01504 1.1e-217 S CAAX protease self-immunity
HHLPMJGF_01505 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHLPMJGF_01506 3.5e-42
HHLPMJGF_01507 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_01508 3.2e-96 S PFAM Archaeal ATPase
HHLPMJGF_01509 1.3e-46
HHLPMJGF_01511 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHLPMJGF_01512 7.9e-158 amtB P ammonium transporter
HHLPMJGF_01513 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HHLPMJGF_01514 1.4e-90 S B3 4 domain
HHLPMJGF_01515 2e-169 L Transposase and inactivated derivatives IS30 family
HHLPMJGF_01534 2.5e-230 L transposase, IS605 OrfB family
HHLPMJGF_01535 2.1e-60 L PFAM transposase IS200-family protein
HHLPMJGF_01537 0.0 L PLD-like domain
HHLPMJGF_01538 1.4e-88 mrr L restriction endonuclease
HHLPMJGF_01539 3.1e-151 L restriction endonuclease
HHLPMJGF_01540 9.7e-62 3.1.21.3 V Type I restriction modification DNA specificity domain
HHLPMJGF_01541 1.4e-44 S RelE-like toxin of type II toxin-antitoxin system HigB
HHLPMJGF_01542 2.6e-38 higA K Helix-turn-helix XRE-family like proteins
HHLPMJGF_01543 4.3e-94 3.1.21.3 L Type I restriction modification DNA specificity domain
HHLPMJGF_01544 0.0 2.7.7.6 M Peptidase family M23
HHLPMJGF_01545 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
HHLPMJGF_01546 2.7e-174 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HHLPMJGF_01547 3.3e-146 cps1D M Domain of unknown function (DUF4422)
HHLPMJGF_01548 9.7e-125 recX 2.4.1.337 GT4 S Regulatory protein RecX
HHLPMJGF_01549 4.9e-31
HHLPMJGF_01550 6.6e-34 S Protein of unknown function (DUF2922)
HHLPMJGF_01551 3.2e-153 yihY S Belongs to the UPF0761 family
HHLPMJGF_01552 1.1e-281 yjeM E Amino Acid
HHLPMJGF_01553 3.6e-255 E Arginine ornithine antiporter
HHLPMJGF_01554 1.7e-220 arcT 2.6.1.1 E Aminotransferase
HHLPMJGF_01555 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HHLPMJGF_01556 6.1e-79 fld C Flavodoxin
HHLPMJGF_01557 2.3e-67 gtcA S Teichoic acid glycosylation protein
HHLPMJGF_01558 9.3e-56
HHLPMJGF_01559 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HHLPMJGF_01561 7.7e-228 yfmL L DEAD DEAH box helicase
HHLPMJGF_01562 1.3e-190 mocA S Oxidoreductase
HHLPMJGF_01563 9.1e-62 S Domain of unknown function (DUF4828)
HHLPMJGF_01564 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HHLPMJGF_01565 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HHLPMJGF_01566 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HHLPMJGF_01567 9.3e-197 S Protein of unknown function (DUF3114)
HHLPMJGF_01568 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HHLPMJGF_01569 1.1e-119 ybhL S Belongs to the BI1 family
HHLPMJGF_01570 3.1e-21
HHLPMJGF_01571 2e-91 K Acetyltransferase (GNAT) family
HHLPMJGF_01572 1.9e-77 K LytTr DNA-binding domain
HHLPMJGF_01573 7.3e-69 S Protein of unknown function (DUF3021)
HHLPMJGF_01574 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HHLPMJGF_01575 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
HHLPMJGF_01576 2.5e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HHLPMJGF_01577 1.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHLPMJGF_01578 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HHLPMJGF_01579 8.3e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHLPMJGF_01580 2.7e-18 S Domain of unknown function DUF1829
HHLPMJGF_01581 0.0 G Peptidase_C39 like family
HHLPMJGF_01582 2.1e-25
HHLPMJGF_01583 0.0 ganB 3.2.1.89 G arabinogalactan
HHLPMJGF_01584 2.8e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
HHLPMJGF_01585 4.8e-215 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HHLPMJGF_01586 2.2e-75 rgpB GT2 M Glycosyl transferase family 2
HHLPMJGF_01587 2.1e-116 S Glycosyltransferase like family 2
HHLPMJGF_01588 3.1e-98 M Glycosyltransferase like family 2
HHLPMJGF_01589 2.6e-97 cps3F
HHLPMJGF_01590 4.1e-41 M biosynthesis protein
HHLPMJGF_01591 1.4e-83 M Domain of unknown function (DUF4422)
HHLPMJGF_01592 2e-87 S Glycosyltransferase like family
HHLPMJGF_01593 0.0 csd1 3.5.1.28 G domain, Protein
HHLPMJGF_01594 1.1e-163 yueF S AI-2E family transporter
HHLPMJGF_01595 3.9e-228 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHLPMJGF_01596 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHLPMJGF_01597 2.2e-34 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HHLPMJGF_01598 3.9e-50 L Bacterial dnaA protein
HHLPMJGF_01599 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HHLPMJGF_01600 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHLPMJGF_01601 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHLPMJGF_01602 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHLPMJGF_01603 4.5e-49 ylxQ J ribosomal protein
HHLPMJGF_01604 1e-44 ylxR K Protein of unknown function (DUF448)
HHLPMJGF_01605 1e-215 nusA K Participates in both transcription termination and antitermination
HHLPMJGF_01606 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HHLPMJGF_01608 3.4e-15
HHLPMJGF_01609 2.1e-49
HHLPMJGF_01610 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHLPMJGF_01611 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHLPMJGF_01612 2.6e-149 purR 2.4.2.7 F pur operon repressor
HHLPMJGF_01613 1.4e-118 znuB U ABC 3 transport family
HHLPMJGF_01614 1.4e-121 fhuC P ABC transporter
HHLPMJGF_01615 2.4e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HHLPMJGF_01616 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HHLPMJGF_01617 6.8e-37 veg S Biofilm formation stimulator VEG
HHLPMJGF_01618 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHLPMJGF_01619 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHLPMJGF_01620 1.9e-155 tatD L hydrolase, TatD family
HHLPMJGF_01621 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHLPMJGF_01622 3.6e-162 yunF F Protein of unknown function DUF72
HHLPMJGF_01624 1e-130 cobB K SIR2 family
HHLPMJGF_01625 1.6e-177
HHLPMJGF_01626 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HHLPMJGF_01627 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HHLPMJGF_01628 3.5e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHLPMJGF_01629 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HHLPMJGF_01630 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
HHLPMJGF_01631 0.0 helD 3.6.4.12 L DNA helicase
HHLPMJGF_01632 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HHLPMJGF_01635 3e-116 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HHLPMJGF_01636 2.1e-49 azlD E Branched-chain amino acid transport
HHLPMJGF_01637 1.4e-119 azlC E azaleucine resistance protein AzlC
HHLPMJGF_01638 7.3e-60 K Aminotransferase class I and II
HHLPMJGF_01639 2.5e-164 K Aminotransferase class I and II
HHLPMJGF_01640 3.6e-288 S amidohydrolase
HHLPMJGF_01642 2.7e-160 S reductase
HHLPMJGF_01643 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
HHLPMJGF_01644 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHLPMJGF_01645 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HHLPMJGF_01646 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHLPMJGF_01647 0.0 asnB 6.3.5.4 E Asparagine synthase
HHLPMJGF_01648 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHLPMJGF_01649 1.9e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHLPMJGF_01650 9.7e-130 jag S R3H domain protein
HHLPMJGF_01651 2.2e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHLPMJGF_01652 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHLPMJGF_01653 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HHLPMJGF_01654 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHLPMJGF_01655 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHLPMJGF_01656 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HHLPMJGF_01657 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HHLPMJGF_01658 1.7e-34 yaaA S S4 domain protein YaaA
HHLPMJGF_01659 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHLPMJGF_01660 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHLPMJGF_01661 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHLPMJGF_01662 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HHLPMJGF_01663 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHLPMJGF_01664 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHLPMJGF_01665 2.1e-95 L Helix-turn-helix domain
HHLPMJGF_01666 3.9e-140 L hmm pf00665
HHLPMJGF_01668 7.6e-61 XK27_01125 L PFAM IS66 Orf2 family protein
HHLPMJGF_01669 2.7e-160 L Transposase IS66 family
HHLPMJGF_01670 1.4e-110 lssY 3.6.1.27 I Acid phosphatase homologues
HHLPMJGF_01671 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HHLPMJGF_01672 1.8e-226 clcA_2 P Chloride transporter, ClC family
HHLPMJGF_01673 8.8e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HHLPMJGF_01674 9.3e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHLPMJGF_01675 2.1e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HHLPMJGF_01676 5.2e-50
HHLPMJGF_01677 0.0 S SEC-C Motif Domain Protein
HHLPMJGF_01678 8.5e-84 KT Putative sugar diacid recognition
HHLPMJGF_01679 2.2e-219 EG GntP family permease
HHLPMJGF_01680 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HHLPMJGF_01681 7.7e-58
HHLPMJGF_01683 3.5e-133 mltD CBM50 M NlpC P60 family protein
HHLPMJGF_01684 5.7e-29
HHLPMJGF_01685 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HHLPMJGF_01686 9.8e-32 ykzG S Belongs to the UPF0356 family
HHLPMJGF_01687 2.4e-78
HHLPMJGF_01688 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHLPMJGF_01689 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HHLPMJGF_01690 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HHLPMJGF_01691 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHLPMJGF_01692 1.2e-274 lpdA 1.8.1.4 C Dehydrogenase
HHLPMJGF_01693 1.4e-47 yktA S Belongs to the UPF0223 family
HHLPMJGF_01694 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HHLPMJGF_01695 0.0 typA T GTP-binding protein TypA
HHLPMJGF_01696 1e-221 ftsW D Belongs to the SEDS family
HHLPMJGF_01697 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HHLPMJGF_01698 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HHLPMJGF_01699 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHLPMJGF_01700 4.3e-197 ylbL T Belongs to the peptidase S16 family
HHLPMJGF_01701 2.6e-80 comEA L Competence protein ComEA
HHLPMJGF_01702 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
HHLPMJGF_01703 0.0 comEC S Competence protein ComEC
HHLPMJGF_01704 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
HHLPMJGF_01705 1.1e-34 rpsT J Binds directly to 16S ribosomal RNA
HHLPMJGF_01706 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHLPMJGF_01707 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHLPMJGF_01708 3.5e-163 S Tetratricopeptide repeat
HHLPMJGF_01709 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHLPMJGF_01710 1.7e-47 L PFAM transposase IS200-family protein
HHLPMJGF_01711 8.8e-71 yneR S Belongs to the HesB IscA family
HHLPMJGF_01712 0.0 S membrane
HHLPMJGF_01713 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HHLPMJGF_01714 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHLPMJGF_01715 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHLPMJGF_01716 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
HHLPMJGF_01717 3.8e-46 gluP 3.4.21.105 S Peptidase, S54 family
HHLPMJGF_01718 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HHLPMJGF_01719 5.6e-183 glk 2.7.1.2 G Glucokinase
HHLPMJGF_01720 3.4e-67 yqhL P Rhodanese-like protein
HHLPMJGF_01721 5.9e-22 S Protein of unknown function (DUF3042)
HHLPMJGF_01722 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHLPMJGF_01723 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
HHLPMJGF_01724 3.4e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHLPMJGF_01725 1.1e-220 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HHLPMJGF_01726 3.9e-12
HHLPMJGF_01727 3.1e-153 P Belongs to the nlpA lipoprotein family
HHLPMJGF_01728 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHLPMJGF_01729 3.7e-51 S Iron-sulfur cluster assembly protein
HHLPMJGF_01730 1e-151
HHLPMJGF_01731 6.6e-174
HHLPMJGF_01732 2.5e-89 dut S Protein conserved in bacteria
HHLPMJGF_01735 8.3e-111 K Transcriptional regulator
HHLPMJGF_01736 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HHLPMJGF_01737 1.6e-54 ysxB J Cysteine protease Prp
HHLPMJGF_01738 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HHLPMJGF_01739 2e-92 folT S ECF transporter, substrate-specific component
HHLPMJGF_01740 0.0 pepN 3.4.11.2 E aminopeptidase
HHLPMJGF_01741 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
HHLPMJGF_01742 9.8e-255 pepC 3.4.22.40 E aminopeptidase
HHLPMJGF_01743 6.5e-210 EGP Major facilitator Superfamily
HHLPMJGF_01744 4.1e-229
HHLPMJGF_01745 5.5e-26 K Transcriptional regulator, HxlR family
HHLPMJGF_01746 1.6e-43 K Transcriptional regulator, HxlR family
HHLPMJGF_01747 2.4e-107 XK27_02070 S Nitroreductase family
HHLPMJGF_01748 2.5e-52 hxlR K Transcriptional regulator, HxlR family
HHLPMJGF_01749 3e-119 GM NmrA-like family
HHLPMJGF_01750 1.7e-70 elaA S Gnat family
HHLPMJGF_01751 1.8e-39 S Cytochrome B5
HHLPMJGF_01752 5.4e-09 S Cytochrome B5
HHLPMJGF_01753 7.8e-41 S Cytochrome B5
HHLPMJGF_01754 2e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
HHLPMJGF_01756 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHLPMJGF_01757 1.1e-240 E amino acid
HHLPMJGF_01758 4.1e-214 npp S type I phosphodiesterase nucleotide pyrophosphatase
HHLPMJGF_01759 3.1e-226 yxiO S Vacuole effluxer Atg22 like
HHLPMJGF_01762 1.7e-84
HHLPMJGF_01763 0.0 copA 3.6.3.54 P P-type ATPase
HHLPMJGF_01764 1.8e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HHLPMJGF_01765 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HHLPMJGF_01766 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HHLPMJGF_01767 1.2e-160 EG EamA-like transporter family
HHLPMJGF_01768 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HHLPMJGF_01769 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHLPMJGF_01770 8.1e-154 KT YcbB domain
HHLPMJGF_01771 5.6e-299 xylB 2.7.1.17 G Belongs to the FGGY kinase family
HHLPMJGF_01772 5.6e-164 xylR GK ROK family
HHLPMJGF_01773 1.3e-28
HHLPMJGF_01774 1.3e-101 ydeN S Serine hydrolase
HHLPMJGF_01775 1e-24 psiE S Phosphate-starvation-inducible E
HHLPMJGF_01776 5.1e-20 psiE S Phosphate-starvation-inducible E
HHLPMJGF_01777 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHLPMJGF_01779 3.8e-176 S Aldo keto reductase
HHLPMJGF_01780 9.9e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HHLPMJGF_01781 0.0 L Helicase C-terminal domain protein
HHLPMJGF_01783 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HHLPMJGF_01784 2.9e-24 S Sugar efflux transporter for intercellular exchange
HHLPMJGF_01785 2.1e-126
HHLPMJGF_01786 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HHLPMJGF_01787 0.0 cadA P P-type ATPase
HHLPMJGF_01788 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
HHLPMJGF_01790 4.8e-154 1.6.5.2 GM NAD(P)H-binding
HHLPMJGF_01791 9e-75 K Transcriptional regulator
HHLPMJGF_01792 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
HHLPMJGF_01793 6.3e-109 proWZ P ABC transporter permease
HHLPMJGF_01794 6.7e-139 proV E ABC transporter, ATP-binding protein
HHLPMJGF_01795 4.5e-104 proW P ABC transporter, permease protein
HHLPMJGF_01796 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HHLPMJGF_01797 1.2e-252 clcA P chloride
HHLPMJGF_01798 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HHLPMJGF_01799 3.1e-103 metI P ABC transporter permease
HHLPMJGF_01800 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHLPMJGF_01801 4.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HHLPMJGF_01802 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HHLPMJGF_01803 3.7e-221 norA EGP Major facilitator Superfamily
HHLPMJGF_01804 4.9e-39 1.3.5.4 S FMN binding
HHLPMJGF_01805 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHLPMJGF_01806 1e-265 yfnA E amino acid
HHLPMJGF_01807 5.4e-256 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHLPMJGF_01808 2.1e-49 ebh D nuclear chromosome segregation
HHLPMJGF_01810 1e-32 UW LPXTG-motif cell wall anchor domain protein
HHLPMJGF_01811 2.9e-47
HHLPMJGF_01812 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHLPMJGF_01813 3.3e-26 mleP3 S Membrane transport protein
HHLPMJGF_01814 5.8e-86 T Transcriptional regulatory protein, C terminal
HHLPMJGF_01815 9.9e-239 T GHKL domain
HHLPMJGF_01816 4.7e-109 S Peptidase propeptide and YPEB domain
HHLPMJGF_01817 7.9e-44 P FAD-binding domain
HHLPMJGF_01818 6e-10 P FAD-binding domain
HHLPMJGF_01819 4.3e-55 yphJ 4.1.1.44 S decarboxylase
HHLPMJGF_01820 1.5e-82 K Bacterial regulatory proteins, tetR family
HHLPMJGF_01821 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHLPMJGF_01822 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HHLPMJGF_01823 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
HHLPMJGF_01824 2.7e-85 C Flavodoxin
HHLPMJGF_01825 5.6e-158 K Transcriptional regulator
HHLPMJGF_01826 6.3e-88 lacA S transferase hexapeptide repeat
HHLPMJGF_01827 9.4e-32 S thiolester hydrolase activity
HHLPMJGF_01828 2e-152 S Alpha beta hydrolase
HHLPMJGF_01829 2.3e-93 padC Q Phenolic acid decarboxylase
HHLPMJGF_01830 3.3e-92 padR K Virulence activator alpha C-term
HHLPMJGF_01831 4.7e-66 GM NAD(P)H-binding
HHLPMJGF_01832 2.3e-155 ypuA S Protein of unknown function (DUF1002)
HHLPMJGF_01833 2.5e-07 T Toxin-antitoxin system, toxin component, MazF family
HHLPMJGF_01834 2.4e-08 T Toxin-antitoxin system, toxin component, MazF family
HHLPMJGF_01835 2e-36
HHLPMJGF_01836 3.8e-70 yqeY S YqeY-like protein
HHLPMJGF_01837 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HHLPMJGF_01838 9.1e-265 glnPH2 P ABC transporter permease
HHLPMJGF_01839 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHLPMJGF_01840 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HHLPMJGF_01841 1e-164 yniA G Phosphotransferase enzyme family
HHLPMJGF_01842 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHLPMJGF_01843 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHLPMJGF_01844 1.2e-52
HHLPMJGF_01845 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHLPMJGF_01846 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
HHLPMJGF_01847 2.8e-57
HHLPMJGF_01848 6.5e-145 sufC O FeS assembly ATPase SufC
HHLPMJGF_01849 1.1e-237 sufD O FeS assembly protein SufD
HHLPMJGF_01850 2.8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHLPMJGF_01851 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
HHLPMJGF_01852 1.6e-271 sufB O assembly protein SufB
HHLPMJGF_01853 3.6e-57 yitW S Iron-sulfur cluster assembly protein
HHLPMJGF_01854 6.1e-160 hipB K Helix-turn-helix
HHLPMJGF_01855 1e-84 nreC K PFAM regulatory protein LuxR
HHLPMJGF_01856 5.8e-38 L PFAM Integrase catalytic region
HHLPMJGF_01859 2.2e-202 ykiI
HHLPMJGF_01860 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HHLPMJGF_01861 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHLPMJGF_01862 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHLPMJGF_01863 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHLPMJGF_01864 3.5e-35
HHLPMJGF_01865 2.5e-212 bacI V MacB-like periplasmic core domain
HHLPMJGF_01866 4.4e-129 V ABC transporter
HHLPMJGF_01867 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHLPMJGF_01868 6.8e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HHLPMJGF_01869 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHLPMJGF_01870 1.5e-146 E Glyoxalase-like domain
HHLPMJGF_01871 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HHLPMJGF_01872 2.9e-96 S reductase
HHLPMJGF_01877 8.1e-260 S Putative peptidoglycan binding domain
HHLPMJGF_01879 5.9e-30 2.7.13.3 T GHKL domain
HHLPMJGF_01880 2.1e-127 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HHLPMJGF_01881 1.2e-152 EG EamA-like transporter family
HHLPMJGF_01882 2.5e-118 L Integrase
HHLPMJGF_01883 1.4e-158 rssA S Phospholipase, patatin family
HHLPMJGF_01884 4.2e-23 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HHLPMJGF_01885 2.1e-85 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HHLPMJGF_01886 6.5e-57 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HHLPMJGF_01887 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HHLPMJGF_01888 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHLPMJGF_01889 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HHLPMJGF_01890 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHLPMJGF_01891 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHLPMJGF_01892 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHLPMJGF_01893 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHLPMJGF_01894 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHLPMJGF_01895 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHLPMJGF_01896 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HHLPMJGF_01897 1.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHLPMJGF_01898 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHLPMJGF_01899 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHLPMJGF_01900 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHLPMJGF_01901 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHLPMJGF_01902 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHLPMJGF_01903 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHLPMJGF_01904 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHLPMJGF_01905 2.9e-24 rpmD J Ribosomal protein L30
HHLPMJGF_01906 8.9e-64 rplO J Binds to the 23S rRNA
HHLPMJGF_01907 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHLPMJGF_01908 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHLPMJGF_01909 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHLPMJGF_01910 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HHLPMJGF_01911 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHLPMJGF_01912 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHLPMJGF_01913 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHLPMJGF_01914 1.1e-62 rplQ J Ribosomal protein L17
HHLPMJGF_01915 8.8e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHLPMJGF_01916 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHLPMJGF_01917 2.2e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHLPMJGF_01918 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHLPMJGF_01919 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHLPMJGF_01920 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HHLPMJGF_01921 8.8e-134 T EAL domain
HHLPMJGF_01922 4.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HHLPMJGF_01923 2.2e-83 GM NAD(P)H-binding
HHLPMJGF_01924 6.1e-88 S membrane
HHLPMJGF_01925 2.1e-74 S membrane
HHLPMJGF_01926 1.8e-104 K Transcriptional regulator C-terminal region
HHLPMJGF_01927 7.6e-163 akr5f 1.1.1.346 S reductase
HHLPMJGF_01928 4.3e-40 K Transcriptional regulator
HHLPMJGF_01929 4.3e-59 K Transcriptional regulator
HHLPMJGF_01930 4.8e-132 ponA V Beta-lactamase enzyme family
HHLPMJGF_01931 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HHLPMJGF_01932 1.2e-214 uhpT EGP Major facilitator Superfamily
HHLPMJGF_01933 2.6e-255 ytjP 3.5.1.18 E Dipeptidase
HHLPMJGF_01934 2.2e-274 arcD S C4-dicarboxylate anaerobic carrier
HHLPMJGF_01938 2.1e-41 ybaN S Protein of unknown function (DUF454)
HHLPMJGF_01939 8.4e-100 dedA 3.1.3.1 S SNARE associated Golgi protein
HHLPMJGF_01940 1.8e-65 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HHLPMJGF_01941 2.4e-59 L Resolvase, N terminal domain
HHLPMJGF_01943 4.4e-237 lmrB EGP Major facilitator Superfamily
HHLPMJGF_01944 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
HHLPMJGF_01954 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHLPMJGF_01955 1.7e-183 S Phosphotransferase system, EIIC

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)