ORF_ID e_value Gene_name EC_number CAZy COGs Description
MFIHALKD_00001 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_00002 6.3e-233 gntT EG Gluconate
MFIHALKD_00003 1.3e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MFIHALKD_00004 2.2e-96 K Acetyltransferase (GNAT) domain
MFIHALKD_00005 4.2e-47
MFIHALKD_00006 0.0 nylA 3.5.1.4 J Belongs to the amidase family
MFIHALKD_00007 2.2e-44
MFIHALKD_00008 4.1e-57 yhaI S Protein of unknown function (DUF805)
MFIHALKD_00009 6.2e-140 IQ reductase
MFIHALKD_00010 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MFIHALKD_00011 1.6e-267 hsdM 2.1.1.72 V type I restriction-modification system
MFIHALKD_00012 4.6e-65 3.1.21.3 V Type I restriction modification DNA specificity domain
MFIHALKD_00013 3.4e-177 L Belongs to the 'phage' integrase family
MFIHALKD_00014 1.8e-97 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain protein
MFIHALKD_00015 4.8e-37 higA K Helix-turn-helix XRE-family like proteins
MFIHALKD_00016 1.8e-44 S RelE-like toxin of type II toxin-antitoxin system HigB
MFIHALKD_00017 3.2e-60 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
MFIHALKD_00019 3.5e-102 mrr L restriction endonuclease
MFIHALKD_00020 1.6e-80 K Putative DNA-binding domain
MFIHALKD_00022 1.6e-18 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MFIHALKD_00023 0.0 L PLD-like domain
MFIHALKD_00025 9.3e-175 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MFIHALKD_00026 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_00027 2.8e-54 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MFIHALKD_00028 4.1e-89 XK27_08850 J Aminoacyl-tRNA editing domain
MFIHALKD_00029 4e-19 relB L Addiction module antitoxin, RelB DinJ family
MFIHALKD_00030 1.4e-24
MFIHALKD_00031 2.1e-286 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MFIHALKD_00032 2.5e-117 K LytTr DNA-binding domain
MFIHALKD_00033 3.8e-208 2.7.13.3 T GHKL domain
MFIHALKD_00035 1.3e-09
MFIHALKD_00037 8.4e-38 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
MFIHALKD_00038 8.8e-44 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
MFIHALKD_00039 1.2e-161 mleP3 S Membrane transport protein
MFIHALKD_00040 8.1e-104 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFIHALKD_00041 4e-52 K transcriptional
MFIHALKD_00042 1.9e-121 T Transcriptional regulatory protein, C terminal
MFIHALKD_00043 1.3e-230 T GHKL domain
MFIHALKD_00044 2.1e-81 S Peptidase propeptide and YPEB domain
MFIHALKD_00045 1.5e-130 K Transcriptional regulator
MFIHALKD_00046 2.3e-126 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MFIHALKD_00047 5.6e-222 4.4.1.8 E Aminotransferase, class I
MFIHALKD_00048 6.7e-100 M Protein of unknown function (DUF3737)
MFIHALKD_00049 5.6e-55 yphJ 4.1.1.44 S decarboxylase
MFIHALKD_00050 1.6e-164 1.1.1.1 C nadph quinone reductase
MFIHALKD_00051 2.9e-90 rocF 3.5.3.1, 3.5.3.11 E Arginase family
MFIHALKD_00052 4.9e-47 K helix_turn_helix, mercury resistance
MFIHALKD_00053 4.2e-30
MFIHALKD_00054 1.5e-166 S Oxidoreductase, aldo keto reductase family protein
MFIHALKD_00055 7.1e-86 C Flavodoxin
MFIHALKD_00056 2.1e-16
MFIHALKD_00058 4.9e-154 K Transcriptional regulator
MFIHALKD_00059 1.1e-87 lacA S transferase hexapeptide repeat
MFIHALKD_00060 3.3e-135 S Hydrolases of the alpha beta superfamily
MFIHALKD_00061 7e-153 S Alpha beta hydrolase
MFIHALKD_00062 8.3e-56 infB UW LPXTG-motif cell wall anchor domain protein
MFIHALKD_00063 1.6e-20 UW LPXTG-motif cell wall anchor domain protein
MFIHALKD_00064 1e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MFIHALKD_00065 9.7e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
MFIHALKD_00066 5.1e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MFIHALKD_00067 1.3e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MFIHALKD_00068 1.5e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MFIHALKD_00069 1.2e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFIHALKD_00070 8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MFIHALKD_00071 3.2e-217 patA 2.6.1.1 E Aminotransferase
MFIHALKD_00072 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MFIHALKD_00073 2.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MFIHALKD_00074 6.5e-57
MFIHALKD_00076 9.9e-136 mltD CBM50 M NlpC P60 family protein
MFIHALKD_00077 5.7e-29
MFIHALKD_00078 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
MFIHALKD_00079 9.8e-32 ykzG S Belongs to the UPF0356 family
MFIHALKD_00080 2.3e-81
MFIHALKD_00081 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFIHALKD_00082 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MFIHALKD_00083 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MFIHALKD_00084 1.8e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFIHALKD_00085 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
MFIHALKD_00086 1.4e-47 yktA S Belongs to the UPF0223 family
MFIHALKD_00087 1.2e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MFIHALKD_00088 0.0 typA T GTP-binding protein TypA
MFIHALKD_00089 1.2e-222 ftsW D Belongs to the SEDS family
MFIHALKD_00090 3.9e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MFIHALKD_00091 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MFIHALKD_00092 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFIHALKD_00093 5.1e-198 ylbL T Belongs to the peptidase S16 family
MFIHALKD_00094 5.2e-81 comEA L Competence protein ComEA
MFIHALKD_00095 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
MFIHALKD_00097 0.0 comEC S Competence protein ComEC
MFIHALKD_00098 1.8e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
MFIHALKD_00099 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
MFIHALKD_00100 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MFIHALKD_00101 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFIHALKD_00102 3.5e-163 S Tetratricopeptide repeat
MFIHALKD_00103 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFIHALKD_00104 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MFIHALKD_00105 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MFIHALKD_00106 4e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
MFIHALKD_00107 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MFIHALKD_00108 6.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MFIHALKD_00109 3.3e-71 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MFIHALKD_00110 2.7e-47 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MFIHALKD_00111 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
MFIHALKD_00112 0.0 trxB2 1.8.1.9 C Thioredoxin domain
MFIHALKD_00113 0.0 M LPXTG-motif cell wall anchor domain protein
MFIHALKD_00114 3.7e-15 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
MFIHALKD_00115 1.2e-193 nss M transferase activity, transferring glycosyl groups
MFIHALKD_00116 1.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
MFIHALKD_00117 1.1e-289 M transferase activity, transferring glycosyl groups
MFIHALKD_00118 7.5e-288 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
MFIHALKD_00119 2.2e-165 asp3 S Accessory Sec secretory system ASP3
MFIHALKD_00120 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MFIHALKD_00121 3.1e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MFIHALKD_00122 7.8e-260 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MFIHALKD_00124 0.0 M family 8
MFIHALKD_00125 8.7e-287 GT2,GT4 M family 8
MFIHALKD_00127 2.9e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MFIHALKD_00128 9.1e-161 rrmA 2.1.1.187 H Methyltransferase
MFIHALKD_00129 1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MFIHALKD_00130 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MFIHALKD_00131 1.2e-10 S Protein of unknown function (DUF4044)
MFIHALKD_00132 8.6e-57
MFIHALKD_00133 3.1e-77 mraZ K Belongs to the MraZ family
MFIHALKD_00134 1e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MFIHALKD_00135 1.5e-56 ftsL D Cell division protein FtsL
MFIHALKD_00136 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MFIHALKD_00137 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFIHALKD_00138 2.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MFIHALKD_00139 7.8e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MFIHALKD_00140 6.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MFIHALKD_00141 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MFIHALKD_00142 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFIHALKD_00143 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MFIHALKD_00144 3.2e-40 yggT S YGGT family
MFIHALKD_00145 1.7e-145 ylmH S S4 domain protein
MFIHALKD_00146 1.9e-42 divIVA D DivIVA domain protein
MFIHALKD_00147 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFIHALKD_00148 1.6e-31 cspA K Cold shock protein
MFIHALKD_00149 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MFIHALKD_00151 2.2e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MFIHALKD_00152 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
MFIHALKD_00153 7.5e-58 XK27_04120 S Putative amino acid metabolism
MFIHALKD_00154 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MFIHALKD_00155 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MFIHALKD_00156 9e-119 S Repeat protein
MFIHALKD_00157 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MFIHALKD_00158 6.9e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFIHALKD_00159 1.2e-135 pnuC H nicotinamide mononucleotide transporter
MFIHALKD_00160 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFIHALKD_00161 4.3e-203
MFIHALKD_00162 9.1e-53
MFIHALKD_00163 9.1e-36
MFIHALKD_00164 2.4e-92 yxkA S Phosphatidylethanolamine-binding protein
MFIHALKD_00165 8.9e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
MFIHALKD_00166 2.9e-179 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
MFIHALKD_00167 2.1e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MFIHALKD_00168 4.9e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MFIHALKD_00169 1.2e-180 galR K Transcriptional regulator
MFIHALKD_00170 2.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
MFIHALKD_00171 6.8e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFIHALKD_00172 1.5e-80 K AsnC family
MFIHALKD_00173 3.3e-80 uspA T universal stress protein
MFIHALKD_00174 4.3e-129 ltrA S Bacterial low temperature requirement A protein (LtrA)
MFIHALKD_00175 1.4e-286 lacS G Transporter
MFIHALKD_00176 5.5e-40
MFIHALKD_00177 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFIHALKD_00178 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MFIHALKD_00179 2.6e-192 yeaN P Transporter, major facilitator family protein
MFIHALKD_00180 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
MFIHALKD_00181 9.9e-85 nrdI F Belongs to the NrdI family
MFIHALKD_00182 1.5e-242 yhdP S Transporter associated domain
MFIHALKD_00183 4.4e-155 ypdB V (ABC) transporter
MFIHALKD_00184 3e-90 GM epimerase
MFIHALKD_00185 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
MFIHALKD_00186 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
MFIHALKD_00187 6.1e-134 XK27_07210 6.1.1.6 S B3 4 domain
MFIHALKD_00188 4e-172 S AI-2E family transporter
MFIHALKD_00189 1.7e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MFIHALKD_00190 3.5e-163
MFIHALKD_00191 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MFIHALKD_00192 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFIHALKD_00193 1.1e-309 lmrA V ABC transporter, ATP-binding protein
MFIHALKD_00194 0.0 yfiC V ABC transporter
MFIHALKD_00195 4.9e-284 pipD E Dipeptidase
MFIHALKD_00196 4.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MFIHALKD_00197 7.1e-130 gntR K UbiC transcription regulator-associated domain protein
MFIHALKD_00198 4.3e-126 I transferase activity, transferring acyl groups other than amino-acyl groups
MFIHALKD_00199 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MFIHALKD_00200 2.7e-244 yagE E amino acid
MFIHALKD_00201 3.5e-140 aroD S Serine hydrolase (FSH1)
MFIHALKD_00202 7.7e-222 L transposase IS116 IS110 IS902 family protein
MFIHALKD_00203 3.3e-242 brnQ U Component of the transport system for branched-chain amino acids
MFIHALKD_00204 1.1e-167 GK ROK family
MFIHALKD_00205 0.0 tetP J elongation factor G
MFIHALKD_00206 5.1e-81 uspA T universal stress protein
MFIHALKD_00207 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
MFIHALKD_00208 7.1e-63
MFIHALKD_00209 5.2e-14
MFIHALKD_00210 3.3e-108
MFIHALKD_00211 3.9e-135 V ABC transporter
MFIHALKD_00212 1.8e-212 EGP Major facilitator Superfamily
MFIHALKD_00213 1.3e-257 G PTS system Galactitol-specific IIC component
MFIHALKD_00214 5.9e-180 1.6.5.5 C Zinc-binding dehydrogenase
MFIHALKD_00215 7e-161
MFIHALKD_00216 1e-72 K Transcriptional regulator
MFIHALKD_00217 3.8e-187 D Alpha beta
MFIHALKD_00218 3.8e-52 ypaA S Protein of unknown function (DUF1304)
MFIHALKD_00219 0.0 yjcE P Sodium proton antiporter
MFIHALKD_00220 1.6e-52 yvlA
MFIHALKD_00221 6.6e-111 P Cobalt transport protein
MFIHALKD_00222 1e-238 cbiO1 S ABC transporter, ATP-binding protein
MFIHALKD_00223 6e-97 S ABC-type cobalt transport system, permease component
MFIHALKD_00224 5.6e-133 S membrane transporter protein
MFIHALKD_00225 4.3e-138 IQ KR domain
MFIHALKD_00226 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
MFIHALKD_00227 4.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MFIHALKD_00228 2.8e-131 S Double zinc ribbon
MFIHALKD_00229 1.4e-200 T GHKL domain
MFIHALKD_00230 8.4e-131 agrA K LytTr DNA-binding domain
MFIHALKD_00231 3.8e-20 S Domain of unknown function (DUF4767)
MFIHALKD_00232 3.1e-138
MFIHALKD_00233 4.3e-129
MFIHALKD_00235 1.2e-08 S Domain of unknown function (DUF5067)
MFIHALKD_00236 5.5e-24 S Domain of unknown function (DUF4767)
MFIHALKD_00238 3.2e-153 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MFIHALKD_00239 2.1e-115 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MFIHALKD_00240 3.7e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MFIHALKD_00241 2.9e-249 yagE E amino acid
MFIHALKD_00242 2.6e-85 dps P Belongs to the Dps family
MFIHALKD_00243 0.0 pacL 3.6.3.8 P P-type ATPase
MFIHALKD_00244 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MFIHALKD_00245 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MFIHALKD_00246 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MFIHALKD_00247 4.5e-146 potB P ABC transporter permease
MFIHALKD_00248 4.9e-140 potC P ABC transporter permease
MFIHALKD_00249 2.1e-207 potD P ABC transporter
MFIHALKD_00250 2.1e-230
MFIHALKD_00251 5.5e-234 EGP Sugar (and other) transporter
MFIHALKD_00252 2.1e-255 yfnA E Amino Acid
MFIHALKD_00253 4.5e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MFIHALKD_00254 5.8e-103 gmk2 2.7.4.8 F Guanylate kinase
MFIHALKD_00255 1.5e-82 zur P Belongs to the Fur family
MFIHALKD_00256 1.2e-16 3.2.1.14 GH18
MFIHALKD_00257 2.2e-151
MFIHALKD_00258 4.4e-39 pspC KT PspC domain protein
MFIHALKD_00259 1.6e-94 K Transcriptional regulator (TetR family)
MFIHALKD_00260 3.4e-220 V domain protein
MFIHALKD_00261 3.4e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFIHALKD_00263 2e-31 S Transglycosylase associated protein
MFIHALKD_00264 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MFIHALKD_00265 2.5e-126 3.1.3.73 G phosphoglycerate mutase
MFIHALKD_00266 2.8e-114 dedA S SNARE associated Golgi protein
MFIHALKD_00267 0.0 helD 3.6.4.12 L DNA helicase
MFIHALKD_00268 9.3e-245 nox C NADH oxidase
MFIHALKD_00269 4.5e-255 nox C NADH oxidase
MFIHALKD_00270 9.2e-161 EG EamA-like transporter family
MFIHALKD_00271 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MFIHALKD_00272 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
MFIHALKD_00273 5.4e-220 S cog cog1373
MFIHALKD_00275 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MFIHALKD_00277 2.3e-228 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFIHALKD_00278 2e-47 K Transcriptional regulator
MFIHALKD_00279 6.2e-117 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MFIHALKD_00280 5.3e-160 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MFIHALKD_00281 1.9e-158 spoU 2.1.1.185 J Methyltransferase
MFIHALKD_00282 2.6e-128 S PFAM Archaeal ATPase
MFIHALKD_00283 6.9e-100 crp_2 K Cyclic nucleotide-binding domain
MFIHALKD_00284 2.5e-127 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
MFIHALKD_00285 2.4e-138 pnuC H nicotinamide mononucleotide transporter
MFIHALKD_00286 7.8e-227 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MFIHALKD_00287 4.2e-101 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MFIHALKD_00288 6e-100 ywlG S Belongs to the UPF0340 family
MFIHALKD_00289 8.3e-54 S ParE toxin of type II toxin-antitoxin system, parDE
MFIHALKD_00290 2e-36 D Antitoxin component of a toxin-antitoxin (TA) module
MFIHALKD_00291 5.5e-193 EGP Major facilitator Superfamily
MFIHALKD_00292 1.1e-118 M Lysin motif
MFIHALKD_00293 3.6e-79
MFIHALKD_00294 8e-101 ltrA S Bacterial low temperature requirement A protein (LtrA)
MFIHALKD_00295 1.9e-199 cytX U Belongs to the purine-cytosine permease (2.A.39) family
MFIHALKD_00296 4.3e-13
MFIHALKD_00297 1.5e-79 S Domain of unknown function (DUF4767)
MFIHALKD_00298 1.8e-198 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MFIHALKD_00299 1.9e-115 S Membrane
MFIHALKD_00300 3.4e-126 O Zinc-dependent metalloprotease
MFIHALKD_00301 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MFIHALKD_00302 5.5e-158 metQ_4 P Belongs to the nlpA lipoprotein family
MFIHALKD_00304 0.0 UW LPXTG-motif cell wall anchor domain protein
MFIHALKD_00305 0.0 UW LPXTG-motif cell wall anchor domain protein
MFIHALKD_00306 0.0 UW LPXTG-motif cell wall anchor domain protein
MFIHALKD_00307 2.2e-65 V Abi-like protein
MFIHALKD_00308 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
MFIHALKD_00309 5.1e-238 lmrB EGP Major facilitator Superfamily
MFIHALKD_00310 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MFIHALKD_00311 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MFIHALKD_00312 1.5e-161 sufD O Uncharacterized protein family (UPF0051)
MFIHALKD_00313 1.6e-42 lytE M LysM domain protein
MFIHALKD_00314 0.0 oppD EP Psort location Cytoplasmic, score
MFIHALKD_00315 8.7e-93 lytE M LysM domain protein
MFIHALKD_00316 1.8e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MFIHALKD_00317 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MFIHALKD_00318 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MFIHALKD_00319 3.3e-173 K AI-2E family transporter
MFIHALKD_00320 4.6e-235 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MFIHALKD_00321 5.1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFIHALKD_00322 1.5e-115 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
MFIHALKD_00323 8.7e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MFIHALKD_00324 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MFIHALKD_00325 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MFIHALKD_00326 1.1e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MFIHALKD_00327 3.3e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MFIHALKD_00328 4.6e-136 K LysR substrate binding domain
MFIHALKD_00329 3.6e-52 azlD S branched-chain amino acid
MFIHALKD_00330 6.1e-139 azlC E AzlC protein
MFIHALKD_00331 2.9e-202 hpk31 2.7.13.3 T Histidine kinase
MFIHALKD_00332 3.8e-125 K response regulator
MFIHALKD_00333 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFIHALKD_00334 1.6e-171 deoR K sugar-binding domain protein
MFIHALKD_00335 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MFIHALKD_00336 4.5e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
MFIHALKD_00337 1.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MFIHALKD_00338 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MFIHALKD_00339 2e-135 XK27_01040 S Protein of unknown function (DUF1129)
MFIHALKD_00340 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MFIHALKD_00341 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
MFIHALKD_00342 3.2e-153 spo0J K Belongs to the ParB family
MFIHALKD_00343 3.9e-139 soj D Sporulation initiation inhibitor
MFIHALKD_00344 1.2e-148 noc K Belongs to the ParB family
MFIHALKD_00345 1.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MFIHALKD_00346 1.7e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MFIHALKD_00347 2.7e-171 rihC 3.2.2.1 F Nucleoside
MFIHALKD_00348 1e-218 nupG F Nucleoside transporter
MFIHALKD_00349 7.7e-223 cycA E Amino acid permease
MFIHALKD_00350 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MFIHALKD_00351 1.5e-264 glnP P ABC transporter
MFIHALKD_00352 4.2e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFIHALKD_00353 1.2e-67 infB UW LPXTG-motif cell wall anchor domain protein
MFIHALKD_00354 7.9e-141 L Belongs to the 'phage' integrase family
MFIHALKD_00355 8.9e-124 L PFAM Integrase catalytic region
MFIHALKD_00356 1.1e-27
MFIHALKD_00357 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MFIHALKD_00358 3.4e-147 ykuT M mechanosensitive ion channel
MFIHALKD_00359 1.5e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
MFIHALKD_00360 5.7e-74 ykuL S (CBS) domain
MFIHALKD_00361 2e-94 S Phosphoesterase
MFIHALKD_00362 2.5e-101 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFIHALKD_00363 2e-141 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MFIHALKD_00364 6e-97 yslB S Protein of unknown function (DUF2507)
MFIHALKD_00365 6.1e-54 trxA O Belongs to the thioredoxin family
MFIHALKD_00366 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MFIHALKD_00367 1.6e-86 cvpA S Colicin V production protein
MFIHALKD_00368 6.1e-48 yrzB S Belongs to the UPF0473 family
MFIHALKD_00369 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MFIHALKD_00370 4.1e-43 yrzL S Belongs to the UPF0297 family
MFIHALKD_00371 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFIHALKD_00372 8.3e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MFIHALKD_00373 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MFIHALKD_00374 5.6e-27 yajC U Preprotein translocase
MFIHALKD_00375 6.9e-190 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MFIHALKD_00376 1e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MFIHALKD_00377 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MFIHALKD_00378 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MFIHALKD_00379 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFIHALKD_00380 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
MFIHALKD_00381 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MFIHALKD_00382 2.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
MFIHALKD_00383 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFIHALKD_00384 6.7e-150 ymfM S Helix-turn-helix domain
MFIHALKD_00385 2.7e-249 ymfH S Peptidase M16
MFIHALKD_00386 7.8e-230 ymfF S Peptidase M16 inactive domain protein
MFIHALKD_00387 1.3e-159 aatB ET ABC transporter substrate-binding protein
MFIHALKD_00388 3.6e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MFIHALKD_00389 3.2e-102 glnP P ABC transporter permease
MFIHALKD_00390 8.7e-93 mreD M rod shape-determining protein MreD
MFIHALKD_00391 5.9e-152 mreC M Involved in formation and maintenance of cell shape
MFIHALKD_00392 1.7e-179 mreB D cell shape determining protein MreB
MFIHALKD_00393 6.8e-121 radC L DNA repair protein
MFIHALKD_00394 2.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MFIHALKD_00395 5.8e-230 ndh 1.6.99.3 C NADH dehydrogenase
MFIHALKD_00396 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MFIHALKD_00397 2.6e-308 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MFIHALKD_00398 4.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MFIHALKD_00399 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
MFIHALKD_00400 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MFIHALKD_00401 1.4e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFIHALKD_00402 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
MFIHALKD_00403 1.9e-239 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MFIHALKD_00404 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFIHALKD_00405 3.6e-293 gadC E amino acid
MFIHALKD_00406 8.8e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
MFIHALKD_00407 4.3e-286 gadC E amino acid
MFIHALKD_00408 2.2e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
MFIHALKD_00409 1.1e-234 pbuG S permease
MFIHALKD_00410 4.9e-262 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MFIHALKD_00411 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MFIHALKD_00412 2.7e-140 S Belongs to the UPF0246 family
MFIHALKD_00413 2.5e-138 S Membrane
MFIHALKD_00414 1.8e-74 4.4.1.5 E Glyoxalase
MFIHALKD_00415 1.5e-21
MFIHALKD_00416 2.7e-85 yueI S Protein of unknown function (DUF1694)
MFIHALKD_00417 3.4e-244 rarA L recombination factor protein RarA
MFIHALKD_00418 4.4e-46
MFIHALKD_00419 4.3e-83 usp6 T universal stress protein
MFIHALKD_00420 6.3e-207 araR K Transcriptional regulator
MFIHALKD_00421 1.4e-158 ytbE 1.1.1.346 S Aldo keto reductase
MFIHALKD_00422 4.5e-100 maa 2.3.1.79 S Maltose O-acetyltransferase
MFIHALKD_00423 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MFIHALKD_00424 9.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MFIHALKD_00425 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
MFIHALKD_00426 4.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MFIHALKD_00427 1.6e-144 K transcriptional regulator, ArsR family
MFIHALKD_00428 6.9e-173 abf G Belongs to the glycosyl hydrolase 43 family
MFIHALKD_00429 3.5e-217 lacY G Oligosaccharide H symporter
MFIHALKD_00430 7.9e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MFIHALKD_00431 2.4e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MFIHALKD_00432 1e-47 gcvH E glycine cleavage
MFIHALKD_00433 1.1e-220 rodA D Belongs to the SEDS family
MFIHALKD_00434 3.9e-31 S Protein of unknown function (DUF2969)
MFIHALKD_00435 1.9e-178 mbl D Cell shape determining protein MreB Mrl
MFIHALKD_00436 3.2e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFIHALKD_00437 1.3e-33 ywzB S Protein of unknown function (DUF1146)
MFIHALKD_00438 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MFIHALKD_00439 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MFIHALKD_00440 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MFIHALKD_00441 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MFIHALKD_00442 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFIHALKD_00443 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MFIHALKD_00444 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFIHALKD_00445 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
MFIHALKD_00446 5.9e-233 pyrP F Permease
MFIHALKD_00447 2e-130 yibF S overlaps another CDS with the same product name
MFIHALKD_00448 5.6e-187 yibE S overlaps another CDS with the same product name
MFIHALKD_00449 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFIHALKD_00450 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFIHALKD_00451 1.9e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MFIHALKD_00452 3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MFIHALKD_00453 7e-169 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MFIHALKD_00454 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MFIHALKD_00455 6e-108 tdk 2.7.1.21 F thymidine kinase
MFIHALKD_00456 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
MFIHALKD_00457 8.1e-115 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MFIHALKD_00458 4e-222 arcD U Amino acid permease
MFIHALKD_00459 9.8e-261 E Arginine ornithine antiporter
MFIHALKD_00460 2.7e-79 argR K Regulates arginine biosynthesis genes
MFIHALKD_00461 1e-237 arcA 3.5.3.6 E Arginine
MFIHALKD_00462 1.8e-195 ampC V Beta-lactamase
MFIHALKD_00463 1.3e-33
MFIHALKD_00464 0.0 M domain protein
MFIHALKD_00465 7.7e-91
MFIHALKD_00466 1.9e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MFIHALKD_00467 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MFIHALKD_00468 1.8e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MFIHALKD_00469 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MFIHALKD_00470 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFIHALKD_00471 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFIHALKD_00472 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFIHALKD_00473 4.2e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MFIHALKD_00474 1.7e-193 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MFIHALKD_00475 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MFIHALKD_00476 4.6e-296 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MFIHALKD_00477 1.3e-243 purD 6.3.4.13 F Belongs to the GARS family
MFIHALKD_00478 5.1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFIHALKD_00479 8.5e-153
MFIHALKD_00480 9.9e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFIHALKD_00481 1.2e-202 camS S sex pheromone
MFIHALKD_00482 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFIHALKD_00483 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MFIHALKD_00484 2.5e-230 L transposase, IS605 OrfB family
MFIHALKD_00485 9.6e-61 L PFAM transposase IS200-family protein
MFIHALKD_00486 3.6e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MFIHALKD_00487 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MFIHALKD_00488 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
MFIHALKD_00489 9.4e-141 IQ reductase
MFIHALKD_00490 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MFIHALKD_00491 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MFIHALKD_00492 7.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MFIHALKD_00493 2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFIHALKD_00494 5.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFIHALKD_00495 1.5e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFIHALKD_00496 1.1e-62 rplQ J Ribosomal protein L17
MFIHALKD_00497 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFIHALKD_00498 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MFIHALKD_00499 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MFIHALKD_00500 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MFIHALKD_00501 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MFIHALKD_00502 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MFIHALKD_00503 3.4e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MFIHALKD_00504 8.9e-64 rplO J Binds to the 23S rRNA
MFIHALKD_00505 2.9e-24 rpmD J Ribosomal protein L30
MFIHALKD_00506 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MFIHALKD_00507 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MFIHALKD_00508 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MFIHALKD_00509 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MFIHALKD_00510 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MFIHALKD_00511 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MFIHALKD_00512 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MFIHALKD_00513 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MFIHALKD_00514 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
MFIHALKD_00515 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MFIHALKD_00516 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MFIHALKD_00517 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MFIHALKD_00518 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MFIHALKD_00519 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MFIHALKD_00520 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MFIHALKD_00521 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
MFIHALKD_00522 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MFIHALKD_00523 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MFIHALKD_00524 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFIHALKD_00525 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MFIHALKD_00526 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MFIHALKD_00527 3.4e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MFIHALKD_00528 2.4e-204 ykiI
MFIHALKD_00529 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFIHALKD_00530 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFIHALKD_00531 1e-110 K Bacterial regulatory proteins, tetR family
MFIHALKD_00532 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MFIHALKD_00533 3.4e-77 ctsR K Belongs to the CtsR family
MFIHALKD_00534 3.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
MFIHALKD_00535 3.4e-180 S Hydrolases of the alpha beta superfamily
MFIHALKD_00536 2.3e-11
MFIHALKD_00542 4.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MFIHALKD_00543 2.3e-276 lysP E amino acid
MFIHALKD_00544 4.5e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
MFIHALKD_00545 2.3e-119 lssY 3.6.1.27 I phosphatase
MFIHALKD_00546 2.1e-82 S Threonine/Serine exporter, ThrE
MFIHALKD_00547 8.1e-129 thrE S Putative threonine/serine exporter
MFIHALKD_00548 1e-30 cspC K Cold shock protein
MFIHALKD_00549 1.8e-124 sirR K iron dependent repressor
MFIHALKD_00550 9.1e-167 czcD P cation diffusion facilitator family transporter
MFIHALKD_00551 2.9e-117 S membrane
MFIHALKD_00552 2.2e-109 S VIT family
MFIHALKD_00553 2.7e-82 usp1 T Belongs to the universal stress protein A family
MFIHALKD_00554 2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MFIHALKD_00555 5.7e-152 glnH ET ABC transporter
MFIHALKD_00556 3.2e-110 gluC P ABC transporter permease
MFIHALKD_00557 1.4e-108 glnP P ABC transporter permease
MFIHALKD_00558 3.5e-219 S CAAX protease self-immunity
MFIHALKD_00559 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFIHALKD_00560 5.1e-54
MFIHALKD_00561 4.9e-73 merR K MerR HTH family regulatory protein
MFIHALKD_00562 9.4e-270 lmrB EGP Major facilitator Superfamily
MFIHALKD_00563 3.3e-119 S Domain of unknown function (DUF4811)
MFIHALKD_00564 6.8e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MFIHALKD_00566 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFIHALKD_00567 1.1e-92 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MFIHALKD_00568 8.5e-187 I Alpha beta
MFIHALKD_00569 2.8e-266 emrY EGP Major facilitator Superfamily
MFIHALKD_00570 4.2e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
MFIHALKD_00571 9.4e-253 yjjP S Putative threonine/serine exporter
MFIHALKD_00572 1e-159 mleR K LysR family
MFIHALKD_00573 7e-251 yflS P Sodium:sulfate symporter transmembrane region
MFIHALKD_00574 9.9e-266 frdC 1.3.5.4 C FAD binding domain
MFIHALKD_00575 2.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MFIHALKD_00576 2.6e-305 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MFIHALKD_00577 1.3e-157 mleR K LysR family
MFIHALKD_00578 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MFIHALKD_00579 5.1e-206 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
MFIHALKD_00580 1.3e-298 L PFAM plasmid pRiA4b ORF-3 family protein
MFIHALKD_00581 3.8e-265 S Uncharacterized protein conserved in bacteria (DUF2252)
MFIHALKD_00584 5.8e-22
MFIHALKD_00585 9.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MFIHALKD_00586 6.7e-75
MFIHALKD_00587 7.3e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MFIHALKD_00588 7.7e-130 ponA V Beta-lactamase enzyme family
MFIHALKD_00589 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MFIHALKD_00590 6.3e-216 uhpT EGP Major facilitator Superfamily
MFIHALKD_00591 5.6e-258 ytjP 3.5.1.18 E Dipeptidase
MFIHALKD_00592 2.2e-274 arcD S C4-dicarboxylate anaerobic carrier
MFIHALKD_00593 3.3e-180 yfeX P Peroxidase
MFIHALKD_00594 4.8e-170 lsa S ABC transporter
MFIHALKD_00595 2.7e-134 I alpha/beta hydrolase fold
MFIHALKD_00596 2.1e-180 MA20_14895 S Conserved hypothetical protein 698
MFIHALKD_00597 1.9e-95 S NADPH-dependent FMN reductase
MFIHALKD_00598 6.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MFIHALKD_00599 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MFIHALKD_00600 7.9e-233 mntH P H( )-stimulated, divalent metal cation uptake system
MFIHALKD_00601 5.4e-08 agrA K LytTr DNA-binding domain
MFIHALKD_00602 3.8e-33 agrA K LytTr DNA-binding domain
MFIHALKD_00604 4.3e-07 S Domain of unknown function (DUF4767)
MFIHALKD_00605 3.2e-79 Q Methyltransferase
MFIHALKD_00606 6.9e-116 ktrA P domain protein
MFIHALKD_00607 1e-238 ktrB P Potassium uptake protein
MFIHALKD_00608 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MFIHALKD_00609 6.6e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MFIHALKD_00610 4.4e-219 G Glycosyl hydrolases family 8
MFIHALKD_00611 5e-243 ydaM M Glycosyl transferase
MFIHALKD_00612 9.2e-145
MFIHALKD_00613 7.3e-124 phoU P Plays a role in the regulation of phosphate uptake
MFIHALKD_00614 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFIHALKD_00615 6.5e-154 pstA P Phosphate transport system permease protein PstA
MFIHALKD_00616 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
MFIHALKD_00617 1.2e-157 pstS P Phosphate
MFIHALKD_00618 7.8e-134 K Transcriptional regulatory protein, C-terminal domain protein
MFIHALKD_00619 1.1e-135 cbiO P ABC transporter
MFIHALKD_00620 3.8e-135 P Cobalt transport protein
MFIHALKD_00621 2.2e-182 nikMN P PDGLE domain
MFIHALKD_00622 2e-73 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFIHALKD_00623 4.9e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFIHALKD_00624 5.7e-163 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MFIHALKD_00625 4.7e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MFIHALKD_00626 2.1e-131 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MFIHALKD_00627 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MFIHALKD_00628 0.0 ureC 3.5.1.5 E Amidohydrolase family
MFIHALKD_00629 2.9e-63 ureB 3.5.1.5 E Urease beta subunit
MFIHALKD_00630 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
MFIHALKD_00631 1.9e-97 ureI S AmiS/UreI family transporter
MFIHALKD_00632 1.8e-223 P ammonium transporter
MFIHALKD_00633 2.6e-17 K Transcriptional regulator, HxlR family
MFIHALKD_00634 9e-184
MFIHALKD_00635 1.2e-97 2.3.1.128 K acetyltransferase
MFIHALKD_00636 3.2e-112 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MFIHALKD_00637 2.2e-93 lysR5 K LysR substrate binding domain
MFIHALKD_00638 6.7e-144 manA 5.3.1.8 G mannose-6-phosphate isomerase
MFIHALKD_00639 2.6e-158 K LysR substrate binding domain
MFIHALKD_00640 2.2e-207 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MFIHALKD_00641 2.4e-64 L Transposase IS200 like
MFIHALKD_00642 1.1e-182 L transposase, IS605 OrfB family
MFIHALKD_00643 2.5e-52 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFIHALKD_00644 3.2e-165
MFIHALKD_00645 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_00646 5.9e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MFIHALKD_00647 2.6e-196 XK27_09615 S reductase
MFIHALKD_00648 6e-100 nqr 1.5.1.36 S reductase
MFIHALKD_00650 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFIHALKD_00651 7.1e-190 1.3.5.4 C FAD binding domain
MFIHALKD_00652 1.6e-51 K LysR substrate binding domain
MFIHALKD_00653 6.7e-179 K Transcriptional regulator, LacI family
MFIHALKD_00654 4.7e-260 G Major Facilitator
MFIHALKD_00655 2.6e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MFIHALKD_00656 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MFIHALKD_00657 4e-267 G Major Facilitator
MFIHALKD_00658 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MFIHALKD_00659 5.8e-290 M domain protein
MFIHALKD_00660 6.7e-268 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
MFIHALKD_00661 6.9e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
MFIHALKD_00662 1e-69
MFIHALKD_00663 9.9e-112 K Transcriptional regulator, TetR family
MFIHALKD_00665 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFIHALKD_00666 3.9e-86
MFIHALKD_00667 6.9e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFIHALKD_00668 4.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFIHALKD_00669 2.4e-261 nox C NADH oxidase
MFIHALKD_00670 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
MFIHALKD_00671 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MFIHALKD_00672 2.3e-167 yvgN C Aldo keto reductase
MFIHALKD_00673 7.8e-137 puuD S peptidase C26
MFIHALKD_00674 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MFIHALKD_00675 2.6e-206 yfeO P Voltage gated chloride channel
MFIHALKD_00676 1.9e-220 sptS 2.7.13.3 T Histidine kinase
MFIHALKD_00677 1.3e-114 K response regulator
MFIHALKD_00678 1.3e-87 2.7.6.5 T Region found in RelA / SpoT proteins
MFIHALKD_00679 3.9e-68
MFIHALKD_00680 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MFIHALKD_00681 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MFIHALKD_00682 1.1e-256 malT G Major Facilitator
MFIHALKD_00683 6.5e-210 phbA 2.3.1.9 I Belongs to the thiolase family
MFIHALKD_00684 3e-173 malR K Transcriptional regulator, LacI family
MFIHALKD_00685 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MFIHALKD_00686 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MFIHALKD_00687 3.1e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFIHALKD_00688 2e-106 wecD3 K PFAM GCN5-related N-acetyltransferase
MFIHALKD_00690 0.0 clpL O associated with various cellular activities
MFIHALKD_00691 2.7e-32
MFIHALKD_00692 3.5e-219 patA 2.6.1.1 E Aminotransferase
MFIHALKD_00693 4.7e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFIHALKD_00694 8.5e-75 osmC O OsmC-like protein
MFIHALKD_00696 4.5e-241 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MFIHALKD_00702 1.8e-99 K LytTr DNA-binding domain
MFIHALKD_00703 5.1e-171 2.7.13.3 T GHKL domain
MFIHALKD_00706 1.2e-266 S Putative peptidoglycan binding domain
MFIHALKD_00707 3.5e-27
MFIHALKD_00708 1.2e-217 bacI V MacB-like periplasmic core domain
MFIHALKD_00709 1.3e-128 V ABC transporter
MFIHALKD_00710 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFIHALKD_00711 3.4e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MFIHALKD_00712 1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFIHALKD_00713 3.4e-146 E Glyoxalase-like domain
MFIHALKD_00714 2.5e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
MFIHALKD_00715 2.2e-96 S reductase
MFIHALKD_00717 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MFIHALKD_00718 4.2e-178 ABC-SBP S ABC transporter
MFIHALKD_00719 3.5e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MFIHALKD_00720 1.2e-67 infB UW LPXTG-motif cell wall anchor domain protein
MFIHALKD_00721 1.4e-182 S Phosphotransferase system, EIIC
MFIHALKD_00722 1.9e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFIHALKD_00723 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_00724 0.0 infB UW LPXTG-motif cell wall anchor domain protein
MFIHALKD_00725 0.0 fhaB M Rib/alpha-like repeat
MFIHALKD_00726 9.3e-121 fhaB M Rib/alpha-like repeat
MFIHALKD_00727 3.8e-85 S Short repeat of unknown function (DUF308)
MFIHALKD_00728 1.5e-79 S Psort location Cytoplasmic, score
MFIHALKD_00729 5.6e-283 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
MFIHALKD_00730 1e-75 hsp O Belongs to the small heat shock protein (HSP20) family
MFIHALKD_00731 3.1e-153 yeaE S Aldo keto
MFIHALKD_00732 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
MFIHALKD_00733 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MFIHALKD_00734 2.4e-149 xth 3.1.11.2 L exodeoxyribonuclease III
MFIHALKD_00736 7.9e-271 pipD E Dipeptidase
MFIHALKD_00737 0.0 yjbQ P TrkA C-terminal domain protein
MFIHALKD_00738 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MFIHALKD_00739 1.6e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFIHALKD_00740 1.5e-83
MFIHALKD_00741 1e-209 L transposase IS116 IS110 IS902 family protein
MFIHALKD_00743 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MFIHALKD_00744 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MFIHALKD_00745 2.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MFIHALKD_00746 3.2e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MFIHALKD_00747 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MFIHALKD_00748 1.2e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MFIHALKD_00749 2.5e-88
MFIHALKD_00750 4.2e-14 L PFAM transposase IS200-family protein
MFIHALKD_00751 1.5e-250 S Uncharacterised protein family (UPF0236)
MFIHALKD_00752 4.5e-39 K Bacterial regulatory proteins, tetR family
MFIHALKD_00753 2.3e-211 norB EGP Major Facilitator
MFIHALKD_00756 4.6e-128 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFIHALKD_00757 4.9e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MFIHALKD_00758 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MFIHALKD_00759 1.3e-35 ynzC S UPF0291 protein
MFIHALKD_00760 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
MFIHALKD_00761 1.6e-117 plsC 2.3.1.51 I Acyltransferase
MFIHALKD_00762 2.4e-141 yabB 2.1.1.223 L Methyltransferase small domain
MFIHALKD_00763 5.4e-49 yazA L GIY-YIG catalytic domain protein
MFIHALKD_00764 7.5e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFIHALKD_00765 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
MFIHALKD_00766 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MFIHALKD_00767 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MFIHALKD_00768 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MFIHALKD_00769 7.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MFIHALKD_00770 4.9e-137 cdsA 2.7.7.41 I Belongs to the CDS family
MFIHALKD_00771 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MFIHALKD_00772 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MFIHALKD_00773 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFIHALKD_00774 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
MFIHALKD_00775 1e-215 nusA K Participates in both transcription termination and antitermination
MFIHALKD_00776 1e-44 ylxR K Protein of unknown function (DUF448)
MFIHALKD_00777 3.8e-48 ylxQ J ribosomal protein
MFIHALKD_00778 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MFIHALKD_00779 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MFIHALKD_00780 4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFIHALKD_00781 5.9e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MFIHALKD_00782 2e-64
MFIHALKD_00783 6.9e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MFIHALKD_00784 5.6e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFIHALKD_00785 0.0 dnaK O Heat shock 70 kDa protein
MFIHALKD_00786 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MFIHALKD_00787 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MFIHALKD_00788 2.2e-276 pipD E Dipeptidase
MFIHALKD_00789 1.4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MFIHALKD_00790 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MFIHALKD_00792 2.8e-57
MFIHALKD_00793 8.3e-179 prmA J Ribosomal protein L11 methyltransferase
MFIHALKD_00794 2.1e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MFIHALKD_00795 1.2e-52
MFIHALKD_00796 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MFIHALKD_00797 1.6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MFIHALKD_00798 5.4e-166 yniA G Phosphotransferase enzyme family
MFIHALKD_00799 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MFIHALKD_00800 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MFIHALKD_00801 1.1e-265 glnPH2 P ABC transporter permease
MFIHALKD_00802 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MFIHALKD_00803 2.1e-68 yqeY S YqeY-like protein
MFIHALKD_00804 4.3e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MFIHALKD_00805 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MFIHALKD_00806 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
MFIHALKD_00807 1.5e-90 bioY S BioY family
MFIHALKD_00808 7.8e-177 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MFIHALKD_00809 6.9e-184 phoH T phosphate starvation-inducible protein PhoH
MFIHALKD_00810 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MFIHALKD_00811 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MFIHALKD_00812 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MFIHALKD_00813 1.8e-147 recO L Involved in DNA repair and RecF pathway recombination
MFIHALKD_00814 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MFIHALKD_00815 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MFIHALKD_00816 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MFIHALKD_00817 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFIHALKD_00818 2.4e-220 patA 2.6.1.1 E Aminotransferase
MFIHALKD_00819 8.4e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
MFIHALKD_00820 5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MFIHALKD_00821 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MFIHALKD_00822 2.3e-30 S Protein of unknown function (DUF2929)
MFIHALKD_00823 0.0 dnaE 2.7.7.7 L DNA polymerase
MFIHALKD_00824 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MFIHALKD_00825 9.3e-169 cvfB S S1 domain
MFIHALKD_00826 5.7e-166 xerD D recombinase XerD
MFIHALKD_00827 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFIHALKD_00828 9e-139 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MFIHALKD_00829 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MFIHALKD_00830 6.5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MFIHALKD_00831 2.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MFIHALKD_00832 7.5e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
MFIHALKD_00833 3.4e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MFIHALKD_00834 2.2e-22 M Lysin motif
MFIHALKD_00835 9.9e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MFIHALKD_00836 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MFIHALKD_00837 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MFIHALKD_00838 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFIHALKD_00839 9.7e-236 S Tetratricopeptide repeat protein
MFIHALKD_00840 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MFIHALKD_00841 0.0 yfmR S ABC transporter, ATP-binding protein
MFIHALKD_00842 7.7e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFIHALKD_00843 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFIHALKD_00844 5.3e-113 hlyIII S protein, hemolysin III
MFIHALKD_00845 2.2e-151 DegV S EDD domain protein, DegV family
MFIHALKD_00846 1e-170 ypmR E lipolytic protein G-D-S-L family
MFIHALKD_00847 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MFIHALKD_00848 4.4e-35 yozE S Belongs to the UPF0346 family
MFIHALKD_00849 6.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MFIHALKD_00850 4.5e-143 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFIHALKD_00851 9.9e-163 dprA LU DNA protecting protein DprA
MFIHALKD_00852 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFIHALKD_00853 1.7e-170 lacX 5.1.3.3 G Aldose 1-epimerase
MFIHALKD_00854 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFIHALKD_00855 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFIHALKD_00856 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFIHALKD_00857 8.9e-86 F NUDIX domain
MFIHALKD_00858 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
MFIHALKD_00859 1.7e-66 yqkB S Belongs to the HesB IscA family
MFIHALKD_00860 2.7e-49
MFIHALKD_00862 8.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MFIHALKD_00863 1.3e-61 asp S Asp23 family, cell envelope-related function
MFIHALKD_00864 2.3e-24
MFIHALKD_00865 7.2e-95
MFIHALKD_00866 8.3e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MFIHALKD_00867 2.2e-182 K Transcriptional regulator, LacI family
MFIHALKD_00868 1.8e-95 L nuclease
MFIHALKD_00869 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
MFIHALKD_00870 1.6e-70
MFIHALKD_00871 3.1e-101 fic D Fic/DOC family
MFIHALKD_00872 2.1e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFIHALKD_00873 9.2e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MFIHALKD_00874 1.1e-30
MFIHALKD_00875 3.8e-193
MFIHALKD_00876 2.7e-24
MFIHALKD_00877 6.3e-28 GT2 M Glycosyltransferase like family 2
MFIHALKD_00878 1.9e-32 2.7.8.12 M Glycosyltransferase, group 2 family protein
MFIHALKD_00879 3.6e-41 M Glycosyltransferase sugar-binding region containing DXD motif
MFIHALKD_00880 3e-53 cps2I S Psort location CytoplasmicMembrane, score
MFIHALKD_00882 1.6e-84 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
MFIHALKD_00883 7.4e-36 M Glycosyltransferase GT-D fold
MFIHALKD_00884 1.5e-64 lsgF M Glycosyl transferase family 2
MFIHALKD_00885 2.1e-48 capM M Bacterial sugar transferase
MFIHALKD_00886 1.1e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MFIHALKD_00887 1.6e-141 epsB M biosynthesis protein
MFIHALKD_00888 1.7e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MFIHALKD_00889 1.2e-67 K Transcriptional regulator, HxlR family
MFIHALKD_00890 1e-128
MFIHALKD_00891 8.9e-104 K DNA-templated transcription, initiation
MFIHALKD_00892 3.3e-36
MFIHALKD_00893 2.7e-94 padC Q Phenolic acid decarboxylase
MFIHALKD_00894 7e-87 padR K Virulence activator alpha C-term
MFIHALKD_00895 3.6e-66 GM NAD(P)H-binding
MFIHALKD_00896 6.9e-160 ypuA S Protein of unknown function (DUF1002)
MFIHALKD_00897 1.2e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
MFIHALKD_00898 2.3e-135 K Transcriptional regulator
MFIHALKD_00899 9.3e-161 akr5f 1.1.1.346 S reductase
MFIHALKD_00900 9.7e-64 yneR
MFIHALKD_00901 1.7e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
MFIHALKD_00902 1.5e-141 T EAL domain
MFIHALKD_00903 2.4e-253 pgaC GT2 M Glycosyl transferase
MFIHALKD_00904 9.5e-86
MFIHALKD_00905 9.3e-201 2.7.7.65 T GGDEF domain
MFIHALKD_00906 4.2e-124 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MFIHALKD_00907 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MFIHALKD_00908 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
MFIHALKD_00909 3.4e-92 folT S ECF transporter, substrate-specific component
MFIHALKD_00910 0.0 pepN 3.4.11.2 E aminopeptidase
MFIHALKD_00911 4.5e-112 ylbE GM NAD dependent epimerase dehydratase family protein
MFIHALKD_00912 2.6e-255 pepC 3.4.22.40 E aminopeptidase
MFIHALKD_00913 7.7e-211 EGP Major facilitator Superfamily
MFIHALKD_00914 1.6e-236
MFIHALKD_00915 1.2e-82 K Transcriptional regulator, HxlR family
MFIHALKD_00916 1.5e-109 XK27_02070 S Nitroreductase family
MFIHALKD_00917 7.3e-52 hxlR K Transcriptional regulator, HxlR family
MFIHALKD_00918 1.4e-121 GM NmrA-like family
MFIHALKD_00919 1.9e-74 elaA S Gnat family
MFIHALKD_00920 1.8e-39 S Cytochrome B5
MFIHALKD_00921 5.4e-09 S Cytochrome B5
MFIHALKD_00922 1.6e-41 S Cytochrome B5
MFIHALKD_00923 3e-220 yxjG_1 E methionine synthase, vitamin-B12 independent
MFIHALKD_00925 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFIHALKD_00926 2.9e-241 E amino acid
MFIHALKD_00927 8.6e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
MFIHALKD_00928 2.1e-227 yxiO S Vacuole effluxer Atg22 like
MFIHALKD_00930 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFIHALKD_00931 5.2e-34
MFIHALKD_00932 3.9e-290 mntH P H( )-stimulated, divalent metal cation uptake system
MFIHALKD_00933 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
MFIHALKD_00934 6.8e-87 ygfC K transcriptional regulator (TetR family)
MFIHALKD_00935 4.4e-173 hrtB V ABC transporter permease
MFIHALKD_00936 4.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MFIHALKD_00937 0.0 yhcA V ABC transporter, ATP-binding protein
MFIHALKD_00938 1e-37
MFIHALKD_00939 1.2e-49 czrA K Transcriptional regulator, ArsR family
MFIHALKD_00940 5.2e-240 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFIHALKD_00941 5.1e-173 scrR K Transcriptional regulator, LacI family
MFIHALKD_00942 1e-24
MFIHALKD_00943 4.2e-107
MFIHALKD_00944 1.5e-214 yttB EGP Major facilitator Superfamily
MFIHALKD_00945 2.6e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MFIHALKD_00946 3.5e-88
MFIHALKD_00947 4.6e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MFIHALKD_00948 3.2e-264 S Putative peptidoglycan binding domain
MFIHALKD_00949 1.8e-124 yciB M ErfK YbiS YcfS YnhG
MFIHALKD_00951 1.3e-102
MFIHALKD_00952 7.9e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MFIHALKD_00953 3.6e-125 S Alpha beta hydrolase
MFIHALKD_00954 2.4e-206 gldA 1.1.1.6 C dehydrogenase
MFIHALKD_00955 1.3e-131 ydiN G Major Facilitator Superfamily
MFIHALKD_00956 4.3e-126 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MFIHALKD_00957 6.5e-54 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MFIHALKD_00958 1e-12 ydiN 5.4.99.5 G Major Facilitator
MFIHALKD_00959 3e-162 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MFIHALKD_00960 1.4e-34
MFIHALKD_00961 4.1e-157 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MFIHALKD_00962 3.5e-109 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MFIHALKD_00963 3.4e-35 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MFIHALKD_00964 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MFIHALKD_00965 1.3e-41
MFIHALKD_00966 2.5e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
MFIHALKD_00967 1.6e-33 K Bacterial transcriptional regulator
MFIHALKD_00968 2e-71 IQ Enoyl-(Acyl carrier protein) reductase
MFIHALKD_00969 3.1e-284 S C4-dicarboxylate anaerobic carrier
MFIHALKD_00970 1.2e-250 nhaC C Na H antiporter NhaC
MFIHALKD_00971 2.1e-241 pbuX F xanthine permease
MFIHALKD_00972 1.7e-281 pipD E Dipeptidase
MFIHALKD_00973 9.7e-169 corA P CorA-like Mg2+ transporter protein
MFIHALKD_00974 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MFIHALKD_00975 2.3e-131 terC P membrane
MFIHALKD_00976 2.1e-54 trxA O Belongs to the thioredoxin family
MFIHALKD_00977 1e-235 mepA V MATE efflux family protein
MFIHALKD_00978 5.5e-92 M domain protein
MFIHALKD_00979 8.9e-56 K Transcriptional regulator, ArsR family
MFIHALKD_00980 6.3e-94 P Cadmium resistance transporter
MFIHALKD_00981 3.1e-136 XK27_08845 S ABC transporter, ATP-binding protein
MFIHALKD_00982 7.3e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MFIHALKD_00983 2.9e-182 ABC-SBP S ABC transporter
MFIHALKD_00984 4.5e-74 M PFAM NLP P60 protein
MFIHALKD_00985 6.2e-46
MFIHALKD_00986 1.9e-88 K Helix-turn-helix domain
MFIHALKD_00987 3.2e-273 S ABC transporter, ATP-binding protein
MFIHALKD_00988 1.3e-142 S Putative ABC-transporter type IV
MFIHALKD_00989 2e-106 NU mannosyl-glycoprotein
MFIHALKD_00990 2.4e-248 brnQ U Component of the transport system for branched-chain amino acids
MFIHALKD_00991 1.1e-231 S Uncharacterized protein conserved in bacteria (DUF2325)
MFIHALKD_00992 1.4e-203 nrnB S DHHA1 domain
MFIHALKD_00993 6.3e-50
MFIHALKD_00994 1.2e-137 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MFIHALKD_00995 1.3e-19 S Domain of unknown function (DUF4767)
MFIHALKD_00996 3.6e-54
MFIHALKD_00997 1.4e-116 yrkL S Flavodoxin-like fold
MFIHALKD_00999 4e-65 yeaO S Protein of unknown function, DUF488
MFIHALKD_01000 6.3e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MFIHALKD_01001 2.3e-204 3.1.3.1 S associated with various cellular activities
MFIHALKD_01002 3.8e-243 S Putative metallopeptidase domain
MFIHALKD_01003 4.6e-48
MFIHALKD_01004 0.0 pepO 3.4.24.71 O Peptidase family M13
MFIHALKD_01005 5.1e-105 K Helix-turn-helix XRE-family like proteins
MFIHALKD_01006 1.9e-89 ymdB S Macro domain protein
MFIHALKD_01007 1.9e-198 EGP Major facilitator Superfamily
MFIHALKD_01008 4.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFIHALKD_01009 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MFIHALKD_01010 2.2e-159 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MFIHALKD_01011 0.0 ysaB V FtsX-like permease family
MFIHALKD_01012 7.5e-135 macB2 V ABC transporter, ATP-binding protein
MFIHALKD_01013 2.4e-181 T PhoQ Sensor
MFIHALKD_01014 7.5e-126 K response regulator
MFIHALKD_01015 2.3e-156 ytbE 1.1.1.346 S Aldo keto reductase
MFIHALKD_01018 7.6e-31 L PFAM transposase IS200-family protein
MFIHALKD_01022 7.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MFIHALKD_01023 6.4e-182 ccpA K catabolite control protein A
MFIHALKD_01024 1.1e-134
MFIHALKD_01025 3.5e-132 yebC K Transcriptional regulatory protein
MFIHALKD_01026 1.7e-179 comGA NU Type II IV secretion system protein
MFIHALKD_01027 5.4e-184 comGB NU type II secretion system
MFIHALKD_01028 7.1e-47 comGC U competence protein ComGC
MFIHALKD_01029 4.9e-78 NU general secretion pathway protein
MFIHALKD_01030 9.3e-41
MFIHALKD_01031 2.4e-69
MFIHALKD_01033 5.7e-152 ytxK 2.1.1.72 L N-6 DNA Methylase
MFIHALKD_01034 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFIHALKD_01035 5e-113 S Calcineurin-like phosphoesterase
MFIHALKD_01036 1e-93 yutD S Protein of unknown function (DUF1027)
MFIHALKD_01037 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MFIHALKD_01038 4.9e-106 S Protein of unknown function (DUF1461)
MFIHALKD_01039 5.5e-110 dedA S SNARE-like domain protein
MFIHALKD_01040 7.4e-58 S Bacterial membrane protein, YfhO
MFIHALKD_01041 5.1e-47 S dextransucrase activity
MFIHALKD_01042 1.5e-160 yueF S AI-2E family transporter
MFIHALKD_01043 1.5e-161 S Psort location CytoplasmicMembrane, score
MFIHALKD_01044 3.4e-216 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MFIHALKD_01045 2.4e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MFIHALKD_01046 1.1e-49 M NlpC P60 family protein
MFIHALKD_01047 9.7e-57 M Peptidase_C39 like family
MFIHALKD_01048 4.5e-55 ponA V the current gene model (or a revised gene model) may contain a frame shift
MFIHALKD_01049 9.3e-65 gntR1 K Transcriptional regulator, GntR family
MFIHALKD_01050 7e-153 V ABC transporter, ATP-binding protein
MFIHALKD_01051 2.4e-116
MFIHALKD_01052 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MFIHALKD_01053 7e-99 S Pfam:DUF3816
MFIHALKD_01054 0.0 clpE O Belongs to the ClpA ClpB family
MFIHALKD_01055 2.9e-27
MFIHALKD_01056 2.7e-39 ptsH G phosphocarrier protein HPR
MFIHALKD_01057 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFIHALKD_01058 1.9e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MFIHALKD_01059 1e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
MFIHALKD_01060 7.4e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFIHALKD_01061 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
MFIHALKD_01062 4.5e-38 L PFAM transposase IS200-family protein
MFIHALKD_01064 2.1e-111 M repeat protein
MFIHALKD_01065 2e-23
MFIHALKD_01066 3.7e-118 M Glycosyltransferase like family 2
MFIHALKD_01067 1.1e-88 S Psort location CytoplasmicMembrane, score
MFIHALKD_01068 2.6e-61 XK27_01125 L PFAM IS66 Orf2 family protein
MFIHALKD_01071 8.7e-65 L PFAM Integrase catalytic region
MFIHALKD_01072 1.5e-194 V Beta-lactamase
MFIHALKD_01073 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MFIHALKD_01074 1.2e-123 yhiD S MgtC family
MFIHALKD_01075 1.5e-115 S GyrI-like small molecule binding domain
MFIHALKD_01076 1.8e-125 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
MFIHALKD_01077 3.8e-183 ybhR V ABC transporter
MFIHALKD_01078 9.4e-91 K Bacterial regulatory proteins, tetR family
MFIHALKD_01079 2.3e-27
MFIHALKD_01080 1.1e-32
MFIHALKD_01082 4e-116 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MFIHALKD_01083 3.2e-50 azlD E Branched-chain amino acid transport
MFIHALKD_01084 1.4e-119 azlC E azaleucine resistance protein AzlC
MFIHALKD_01085 3.6e-255 K Aminotransferase class I and II
MFIHALKD_01086 1e-298 S amidohydrolase
MFIHALKD_01087 7e-161 S reductase
MFIHALKD_01088 4.1e-89 2.3.1.183 M Acetyltransferase GNAT family
MFIHALKD_01089 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MFIHALKD_01090 2.4e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
MFIHALKD_01091 9e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MFIHALKD_01092 0.0 asnB 6.3.5.4 E Asparagine synthase
MFIHALKD_01093 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MFIHALKD_01094 9.6e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MFIHALKD_01095 1.7e-134 jag S R3H domain protein
MFIHALKD_01096 1e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFIHALKD_01097 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MFIHALKD_01098 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MFIHALKD_01099 1.9e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MFIHALKD_01100 8.5e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MFIHALKD_01101 1.7e-34 yaaA S S4 domain protein YaaA
MFIHALKD_01102 7.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFIHALKD_01103 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFIHALKD_01104 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFIHALKD_01105 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MFIHALKD_01106 2.2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MFIHALKD_01107 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MFIHALKD_01108 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MFIHALKD_01109 4.4e-74 rplI J Binds to the 23S rRNA
MFIHALKD_01110 4.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MFIHALKD_01111 8.4e-205 yttB EGP Major facilitator Superfamily
MFIHALKD_01112 3.6e-57
MFIHALKD_01113 4.3e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
MFIHALKD_01114 1.3e-123 Z012_01130 S Fic/DOC family
MFIHALKD_01116 1.2e-73 K helix_turn_helix multiple antibiotic resistance protein
MFIHALKD_01117 2.4e-311 lmrA 3.6.3.44 V ABC transporter
MFIHALKD_01119 3.1e-130 K response regulator
MFIHALKD_01120 0.0 vicK 2.7.13.3 T Histidine kinase
MFIHALKD_01121 2.1e-249 yycH S YycH protein
MFIHALKD_01122 5.4e-150 yycI S YycH protein
MFIHALKD_01123 2.9e-153 vicX 3.1.26.11 S domain protein
MFIHALKD_01124 2.1e-217 htrA 3.4.21.107 O serine protease
MFIHALKD_01126 1.1e-54
MFIHALKD_01127 1.4e-113 frnE Q DSBA-like thioredoxin domain
MFIHALKD_01128 1.3e-162 I alpha/beta hydrolase fold
MFIHALKD_01129 8.4e-20 K Helix-turn-helix XRE-family like proteins
MFIHALKD_01130 1.1e-35 S Phage derived protein Gp49-like (DUF891)
MFIHALKD_01132 3e-49 yrvD S Pfam:DUF1049
MFIHALKD_01133 6.9e-150 3.1.3.102, 3.1.3.104 S hydrolase
MFIHALKD_01134 5.2e-89 ntd 2.4.2.6 F Nucleoside
MFIHALKD_01135 1.2e-18
MFIHALKD_01136 4.7e-165 S Alpha/beta hydrolase of unknown function (DUF915)
MFIHALKD_01137 8.1e-114 yviA S Protein of unknown function (DUF421)
MFIHALKD_01138 9.1e-72 S Protein of unknown function (DUF3290)
MFIHALKD_01139 1.3e-41 ybaN S Protein of unknown function (DUF454)
MFIHALKD_01140 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFIHALKD_01141 2.5e-150 endA V DNA/RNA non-specific endonuclease
MFIHALKD_01142 7.8e-255 yifK E Amino acid permease
MFIHALKD_01144 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFIHALKD_01145 8.7e-221 N Uncharacterized conserved protein (DUF2075)
MFIHALKD_01146 5.1e-122 S SNARE associated Golgi protein
MFIHALKD_01147 0.0 uvrA3 L excinuclease ABC, A subunit
MFIHALKD_01148 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFIHALKD_01149 2.4e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFIHALKD_01150 1.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFIHALKD_01151 8.7e-145 S DUF218 domain
MFIHALKD_01152 0.0 ubiB S ABC1 family
MFIHALKD_01153 8.5e-246 yhdP S Transporter associated domain
MFIHALKD_01154 1.9e-74 copY K Copper transport repressor CopY TcrY
MFIHALKD_01155 8.7e-246 EGP Major facilitator Superfamily
MFIHALKD_01156 4.5e-74 yeaL S UPF0756 membrane protein
MFIHALKD_01157 1e-80 yphH S Cupin domain
MFIHALKD_01158 4.7e-82 C Flavodoxin
MFIHALKD_01159 5.5e-161 K LysR substrate binding domain protein
MFIHALKD_01160 2.1e-68 K Bacterial transcriptional regulator
MFIHALKD_01161 4.6e-130 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFIHALKD_01162 5.5e-134 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MFIHALKD_01163 4e-217 uxaC 5.3.1.12 G glucuronate isomerase
MFIHALKD_01164 1.1e-215 uxuT G MFS/sugar transport protein
MFIHALKD_01165 1.3e-180 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MFIHALKD_01166 1.5e-209 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
MFIHALKD_01167 1.5e-52 kdgR K FCD domain
MFIHALKD_01168 4.3e-125 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MFIHALKD_01169 2.3e-167 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MFIHALKD_01170 1.4e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MFIHALKD_01171 6.7e-127 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MFIHALKD_01172 4.9e-151 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MFIHALKD_01174 3.6e-94 S module of peptide synthetase
MFIHALKD_01175 6.2e-226 uxaC 5.3.1.12 G glucuronate isomerase
MFIHALKD_01176 3e-220 yjmB G MFS/sugar transport protein
MFIHALKD_01177 2.4e-96 exuR K Periplasmic binding protein domain
MFIHALKD_01178 9.4e-169 1.1.1.346 C Aldo keto reductase
MFIHALKD_01179 2.1e-39 gcvR T Belongs to the UPF0237 family
MFIHALKD_01180 1.8e-240 XK27_08635 S UPF0210 protein
MFIHALKD_01181 2.4e-95 K Acetyltransferase (GNAT) domain
MFIHALKD_01182 4.4e-160 S Alpha beta hydrolase
MFIHALKD_01183 1.7e-159 gspA M family 8
MFIHALKD_01184 1.4e-122 L transposase, IS605 OrfB family
MFIHALKD_01185 1.1e-89 L transposase, IS605 OrfB family
MFIHALKD_01186 5.6e-77 tlpA2 L Transposase IS200 like
MFIHALKD_01187 2.3e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MFIHALKD_01188 5.8e-94
MFIHALKD_01189 6.4e-162 degV S EDD domain protein, DegV family
MFIHALKD_01190 0.0 FbpA K Fibronectin-binding protein
MFIHALKD_01191 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MFIHALKD_01192 3.9e-209 carA 6.3.5.5 F Belongs to the CarA family
MFIHALKD_01193 1.8e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MFIHALKD_01194 3.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFIHALKD_01195 1.5e-65 esbA S Family of unknown function (DUF5322)
MFIHALKD_01196 1.8e-71 rnhA 3.1.26.4 L Ribonuclease HI
MFIHALKD_01197 8.6e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MFIHALKD_01198 1.6e-82 F Belongs to the NrdI family
MFIHALKD_01199 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MFIHALKD_01200 8.9e-104 ypsA S Belongs to the UPF0398 family
MFIHALKD_01201 2.9e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MFIHALKD_01202 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MFIHALKD_01203 1.8e-162 EG EamA-like transporter family
MFIHALKD_01204 1.1e-124 dnaD L DnaD domain protein
MFIHALKD_01205 1.7e-85 ypmB S Protein conserved in bacteria
MFIHALKD_01206 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MFIHALKD_01207 3.9e-173 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MFIHALKD_01208 2.1e-161 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MFIHALKD_01209 9.3e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MFIHALKD_01210 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MFIHALKD_01211 3.8e-87 S Protein of unknown function (DUF1440)
MFIHALKD_01212 0.0 rafA 3.2.1.22 G alpha-galactosidase
MFIHALKD_01213 7.7e-191 galR K Periplasmic binding protein-like domain
MFIHALKD_01214 4.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MFIHALKD_01215 8.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MFIHALKD_01216 2.6e-124 lrgB M LrgB-like family
MFIHALKD_01217 1.9e-66 lrgA S LrgA family
MFIHALKD_01218 1.1e-130 lytT K response regulator receiver
MFIHALKD_01219 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
MFIHALKD_01220 4e-148 f42a O Band 7 protein
MFIHALKD_01221 5e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MFIHALKD_01222 6.4e-156 yitU 3.1.3.104 S hydrolase
MFIHALKD_01223 9.2e-39 S Cytochrome B5
MFIHALKD_01224 9.8e-115 nreC K PFAM regulatory protein LuxR
MFIHALKD_01225 6.1e-160 hipB K Helix-turn-helix
MFIHALKD_01226 6.2e-57 yitW S Iron-sulfur cluster assembly protein
MFIHALKD_01227 3.6e-271 sufB O assembly protein SufB
MFIHALKD_01228 3.2e-80 nifU C SUF system FeS assembly protein, NifU family
MFIHALKD_01229 2e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFIHALKD_01230 1.5e-239 sufD O FeS assembly protein SufD
MFIHALKD_01231 6.5e-145 sufC O FeS assembly ATPase SufC
MFIHALKD_01232 1.2e-31 feoA P FeoA domain
MFIHALKD_01233 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MFIHALKD_01234 6.1e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MFIHALKD_01235 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MFIHALKD_01236 1.7e-63 ydiI Q Thioesterase superfamily
MFIHALKD_01237 2.4e-109 yvrI K sigma factor activity
MFIHALKD_01238 5e-202 G Transporter, major facilitator family protein
MFIHALKD_01239 0.0 S Bacterial membrane protein YfhO
MFIHALKD_01240 1.5e-103 T Ion transport 2 domain protein
MFIHALKD_01250 3.7e-103 L Integrase core domain
MFIHALKD_01251 2.7e-52 L Integrase core domain
MFIHALKD_01252 4.1e-124 L Integrase core domain
MFIHALKD_01253 9.6e-138 L Bacterial dnaA protein
MFIHALKD_01254 2.3e-78 O Bacterial dnaA protein
MFIHALKD_01255 6e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MFIHALKD_01256 2.2e-151 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MFIHALKD_01258 1.4e-92 L Reverse transcriptase (RNA-dependent DNA polymerase)
MFIHALKD_01260 9.6e-63 S TM2 domain
MFIHALKD_01263 6.2e-22
MFIHALKD_01264 1.7e-30 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MFIHALKD_01265 1.6e-18 QT PucR C-terminal helix-turn-helix domain
MFIHALKD_01267 6.7e-61
MFIHALKD_01269 8.2e-70 O Preprotein translocase subunit SecB
MFIHALKD_01270 1.2e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MFIHALKD_01271 4.5e-250 mmuP E amino acid
MFIHALKD_01273 1.1e-08 K Psort location Cytoplasmic, score
MFIHALKD_01274 5.3e-07 K Psort location Cytoplasmic, score
MFIHALKD_01276 2e-143 ywqE 3.1.3.48 GM PHP domain protein
MFIHALKD_01277 7.1e-99 M Glycosyl hydrolases family 25
MFIHALKD_01278 1.2e-210 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MFIHALKD_01279 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MFIHALKD_01281 3.3e-85 L PFAM transposase IS200-family protein
MFIHALKD_01282 7.6e-31 L PFAM transposase IS200-family protein
MFIHALKD_01289 7.1e-133 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MFIHALKD_01290 1.4e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MFIHALKD_01291 4.2e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFIHALKD_01292 1.3e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MFIHALKD_01293 3.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MFIHALKD_01294 2e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MFIHALKD_01295 3e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFIHALKD_01296 3.5e-129 IQ reductase
MFIHALKD_01297 7.5e-156 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MFIHALKD_01298 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFIHALKD_01299 7.9e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFIHALKD_01300 4.2e-77 marR K Transcriptional regulator, MarR family
MFIHALKD_01301 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MFIHALKD_01303 3.3e-200 xerS L Belongs to the 'phage' integrase family
MFIHALKD_01304 2.1e-236 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MFIHALKD_01305 3.2e-158 rssA S Phospholipase, patatin family
MFIHALKD_01306 2.5e-118 L Integrase
MFIHALKD_01307 9.5e-153 EG EamA-like transporter family
MFIHALKD_01308 1.6e-128 narI 1.7.5.1 C Nitrate reductase
MFIHALKD_01309 4.3e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
MFIHALKD_01310 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
MFIHALKD_01311 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFIHALKD_01312 5.7e-186 moeB 2.7.7.73, 2.7.7.80 H ThiF family
MFIHALKD_01313 1.5e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MFIHALKD_01314 5.3e-223 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
MFIHALKD_01315 7.5e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MFIHALKD_01316 3.7e-94 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MFIHALKD_01317 6.3e-42
MFIHALKD_01318 2.3e-182 comP 2.7.13.3 F Sensor histidine kinase
MFIHALKD_01319 4.9e-114 nreC K PFAM regulatory protein LuxR
MFIHALKD_01320 7.2e-19
MFIHALKD_01321 8.4e-179
MFIHALKD_01322 6.3e-144 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
MFIHALKD_01323 5.6e-217 narK P Transporter, major facilitator family protein
MFIHALKD_01324 3.9e-32 moaD 2.8.1.12 H ThiS family
MFIHALKD_01325 3.5e-62 moaE 2.8.1.12 H MoaE protein
MFIHALKD_01326 4.7e-76 S Flavodoxin
MFIHALKD_01327 1e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFIHALKD_01328 1.1e-125 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
MFIHALKD_01329 1.7e-174 fecB P Periplasmic binding protein
MFIHALKD_01330 2.5e-175
MFIHALKD_01331 1.6e-76
MFIHALKD_01332 2.9e-114 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MFIHALKD_01333 0.0 S SEC-C Motif Domain Protein
MFIHALKD_01334 3.6e-51
MFIHALKD_01335 6.4e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MFIHALKD_01336 3.2e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MFIHALKD_01337 4.2e-118 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MFIHALKD_01338 1.1e-231 clcA_2 P Chloride transporter, ClC family
MFIHALKD_01339 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MFIHALKD_01340 2e-112 lssY 3.6.1.27 I Acid phosphatase homologues
MFIHALKD_01341 2.9e-53 XK27_01125 L PFAM IS66 Orf2 family protein
MFIHALKD_01342 1.2e-170 yrvN L AAA C-terminal domain
MFIHALKD_01343 5.7e-31 K Helix-turn-helix XRE-family like proteins
MFIHALKD_01344 1.1e-130 IQ Dehydrogenase reductase
MFIHALKD_01345 4.9e-37
MFIHALKD_01346 5.7e-115 ywnB S NAD(P)H-binding
MFIHALKD_01347 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
MFIHALKD_01348 4e-254 nhaC C Na H antiporter NhaC
MFIHALKD_01349 1.6e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFIHALKD_01351 3.1e-98 ydeN S Serine hydrolase
MFIHALKD_01352 4.5e-62 psiE S Phosphate-starvation-inducible E
MFIHALKD_01353 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFIHALKD_01355 7.5e-144 K helix_turn_helix, arabinose operon control protein
MFIHALKD_01356 1.2e-85 S Membrane
MFIHALKD_01357 0.0 rafA 3.2.1.22 G alpha-galactosidase
MFIHALKD_01358 8.2e-179 S Aldo keto reductase
MFIHALKD_01359 8.4e-82 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
MFIHALKD_01360 0.0 L Helicase C-terminal domain protein
MFIHALKD_01362 5e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MFIHALKD_01363 1.8e-53 S Sugar efflux transporter for intercellular exchange
MFIHALKD_01364 1.3e-128
MFIHALKD_01365 1.2e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MFIHALKD_01366 0.0 cadA P P-type ATPase
MFIHALKD_01367 1.5e-217 5.4.2.7 G Metalloenzyme superfamily
MFIHALKD_01369 5.1e-156 1.6.5.2 GM NAD(P)H-binding
MFIHALKD_01370 5.3e-75 K Transcriptional regulator
MFIHALKD_01371 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
MFIHALKD_01372 4.1e-105 proWZ P ABC transporter permease
MFIHALKD_01373 4.2e-141 proV E ABC transporter, ATP-binding protein
MFIHALKD_01374 2.4e-97 proW P ABC transporter, permease protein
MFIHALKD_01375 2.5e-127 C Zinc-binding dehydrogenase
MFIHALKD_01376 7.4e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MFIHALKD_01377 5.4e-253 clcA P chloride
MFIHALKD_01378 7.5e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MFIHALKD_01379 3.1e-103 metI P ABC transporter permease
MFIHALKD_01380 1.2e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFIHALKD_01381 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
MFIHALKD_01382 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MFIHALKD_01383 1.3e-221 norA EGP Major facilitator Superfamily
MFIHALKD_01384 2.5e-43 1.3.5.4 S FMN binding
MFIHALKD_01385 3.2e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFIHALKD_01386 1.8e-265 yfnA E amino acid
MFIHALKD_01387 3.1e-256 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFIHALKD_01389 1.2e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MFIHALKD_01390 0.0 helD 3.6.4.12 L DNA helicase
MFIHALKD_01391 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
MFIHALKD_01392 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MFIHALKD_01393 5e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MFIHALKD_01394 8.2e-163 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MFIHALKD_01395 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MFIHALKD_01396 1.1e-178
MFIHALKD_01397 4.4e-121 cobB K SIR2 family
MFIHALKD_01399 1.8e-161 yunF F Protein of unknown function DUF72
MFIHALKD_01400 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFIHALKD_01401 7.1e-155 tatD L hydrolase, TatD family
MFIHALKD_01402 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MFIHALKD_01403 4.9e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MFIHALKD_01404 6.8e-37 veg S Biofilm formation stimulator VEG
MFIHALKD_01405 9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MFIHALKD_01406 6.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
MFIHALKD_01407 7.7e-123 fhuC P ABC transporter
MFIHALKD_01408 1.6e-127 znuB U ABC 3 transport family
MFIHALKD_01409 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MFIHALKD_01410 1.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFIHALKD_01411 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFIHALKD_01412 5.6e-50
MFIHALKD_01413 2.5e-147 yxeH S hydrolase
MFIHALKD_01414 1.3e-270 ywfO S HD domain protein
MFIHALKD_01415 5e-148 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MFIHALKD_01416 5.2e-53 ywiB S Domain of unknown function (DUF1934)
MFIHALKD_01417 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MFIHALKD_01418 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MFIHALKD_01419 1.4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFIHALKD_01420 4.6e-41 rpmE2 J Ribosomal protein L31
MFIHALKD_01421 1.7e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFIHALKD_01422 6.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
MFIHALKD_01423 1.5e-124 srtA 3.4.22.70 M sortase family
MFIHALKD_01424 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MFIHALKD_01425 8.8e-158 3.2.1.55 GH51 G Right handed beta helix region
MFIHALKD_01426 1.2e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFIHALKD_01427 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MFIHALKD_01428 7.8e-120 pgm3 G Belongs to the phosphoglycerate mutase family
MFIHALKD_01429 1.7e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFIHALKD_01430 7e-93 lemA S LemA family
MFIHALKD_01431 1.5e-158 htpX O Belongs to the peptidase M48B family
MFIHALKD_01432 5.8e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MFIHALKD_01433 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MFIHALKD_01434 0.0 sprD D Domain of Unknown Function (DUF1542)
MFIHALKD_01435 5.9e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
MFIHALKD_01436 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MFIHALKD_01437 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFIHALKD_01438 1.9e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
MFIHALKD_01439 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFIHALKD_01441 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MFIHALKD_01442 1.5e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFIHALKD_01443 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
MFIHALKD_01444 1.2e-250 U Belongs to the purine-cytosine permease (2.A.39) family
MFIHALKD_01445 6.1e-243 codA 3.5.4.1 F cytosine deaminase
MFIHALKD_01446 3.1e-147 tesE Q hydratase
MFIHALKD_01448 1.8e-113 S (CBS) domain
MFIHALKD_01449 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MFIHALKD_01450 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MFIHALKD_01451 6.2e-39 yabO J S4 domain protein
MFIHALKD_01452 5.6e-56 divIC D Septum formation initiator
MFIHALKD_01453 9.8e-67 yabR J RNA binding
MFIHALKD_01454 1.8e-262 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MFIHALKD_01455 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MFIHALKD_01456 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFIHALKD_01457 3.6e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MFIHALKD_01458 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFIHALKD_01459 2.7e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MFIHALKD_01460 1.9e-28
MFIHALKD_01468 2.9e-44 L Belongs to the 'phage' integrase family
MFIHALKD_01482 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MFIHALKD_01483 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MFIHALKD_01484 3.6e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MFIHALKD_01485 7.5e-202 coiA 3.6.4.12 S Competence protein
MFIHALKD_01486 1.3e-262 pipD E Dipeptidase
MFIHALKD_01487 5.3e-113 yjbH Q Thioredoxin
MFIHALKD_01488 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
MFIHALKD_01489 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFIHALKD_01490 2e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MFIHALKD_01491 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MFIHALKD_01492 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
MFIHALKD_01493 6.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MFIHALKD_01494 5.4e-164 lutA C Cysteine-rich domain
MFIHALKD_01495 5.8e-288 lutB C 4Fe-4S dicluster domain
MFIHALKD_01496 4.3e-135 yrjD S LUD domain
MFIHALKD_01497 7.2e-30
MFIHALKD_01498 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MFIHALKD_01499 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MFIHALKD_01500 2.6e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFIHALKD_01501 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MFIHALKD_01502 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MFIHALKD_01503 3.1e-32 KT PspC domain protein
MFIHALKD_01504 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MFIHALKD_01505 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MFIHALKD_01506 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MFIHALKD_01507 3.6e-112 comFC S Competence protein
MFIHALKD_01508 2.1e-252 comFA L Helicase C-terminal domain protein
MFIHALKD_01509 2.3e-108 yvyE 3.4.13.9 S YigZ family
MFIHALKD_01510 3e-39 C nitroreductase
MFIHALKD_01511 7.4e-237 EGP Major facilitator Superfamily
MFIHALKD_01512 3.3e-68 rmaI K Transcriptional regulator
MFIHALKD_01513 6e-39
MFIHALKD_01514 0.0 ydaO E amino acid
MFIHALKD_01515 8.1e-304 ybeC E amino acid
MFIHALKD_01516 2.1e-85 S Aminoacyl-tRNA editing domain
MFIHALKD_01517 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MFIHALKD_01518 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MFIHALKD_01520 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MFIHALKD_01521 0.0 uup S ABC transporter, ATP-binding protein
MFIHALKD_01522 1.2e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFIHALKD_01523 4.2e-225 mtnE 2.6.1.83 E Aminotransferase
MFIHALKD_01524 7.3e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MFIHALKD_01525 1.7e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFIHALKD_01526 2.8e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MFIHALKD_01527 4.2e-133 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFIHALKD_01528 1.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MFIHALKD_01529 1.6e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MFIHALKD_01530 8.6e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MFIHALKD_01531 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MFIHALKD_01532 2.5e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MFIHALKD_01533 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MFIHALKD_01534 1.2e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MFIHALKD_01535 1.1e-136 fat 3.1.2.21 I Acyl-ACP thioesterase
MFIHALKD_01536 5.8e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MFIHALKD_01537 5.9e-58 yabA L Involved in initiation control of chromosome replication
MFIHALKD_01538 4e-184 holB 2.7.7.7 L DNA polymerase III
MFIHALKD_01539 7.6e-52 yaaQ S Cyclic-di-AMP receptor
MFIHALKD_01540 1.1e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFIHALKD_01541 9.7e-39 S Protein of unknown function (DUF2508)
MFIHALKD_01542 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MFIHALKD_01543 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MFIHALKD_01544 5.1e-302 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFIHALKD_01545 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MFIHALKD_01546 3.4e-35 nrdH O Glutaredoxin
MFIHALKD_01547 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFIHALKD_01548 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFIHALKD_01549 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MFIHALKD_01550 6e-132 S Putative adhesin
MFIHALKD_01551 5.1e-73 XK27_06920 S Protein of unknown function (DUF1700)
MFIHALKD_01552 4.4e-55 K transcriptional regulator PadR family
MFIHALKD_01553 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MFIHALKD_01555 7.7e-48
MFIHALKD_01556 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MFIHALKD_01557 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MFIHALKD_01558 3.1e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MFIHALKD_01559 4e-245 M Glycosyl transferase family group 2
MFIHALKD_01561 1.6e-227 aadAT EK Aminotransferase, class I
MFIHALKD_01562 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MFIHALKD_01563 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MFIHALKD_01564 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
MFIHALKD_01565 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MFIHALKD_01566 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MFIHALKD_01567 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFIHALKD_01568 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MFIHALKD_01569 2.5e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MFIHALKD_01570 5e-207 yacL S domain protein
MFIHALKD_01571 1.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MFIHALKD_01572 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MFIHALKD_01573 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
MFIHALKD_01574 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MFIHALKD_01575 3e-267 pepC 3.4.22.40 E Peptidase C1-like family
MFIHALKD_01576 5.6e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MFIHALKD_01577 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MFIHALKD_01578 1.1e-119 tcyB E ABC transporter
MFIHALKD_01579 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MFIHALKD_01580 3.1e-169 I alpha/beta hydrolase fold
MFIHALKD_01581 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFIHALKD_01582 0.0 S Bacterial membrane protein, YfhO
MFIHALKD_01583 1.1e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MFIHALKD_01584 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MFIHALKD_01586 1.5e-85 ydcK S Belongs to the SprT family
MFIHALKD_01587 0.0 yhgF K Tex-like protein N-terminal domain protein
MFIHALKD_01588 6.7e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MFIHALKD_01589 4.2e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFIHALKD_01590 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
MFIHALKD_01591 2.4e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MFIHALKD_01592 3.9e-298 aspT P Predicted Permease Membrane Region
MFIHALKD_01593 2e-250 EGP Major facilitator Superfamily
MFIHALKD_01594 1.1e-113
MFIHALKD_01597 5.5e-155 yjjH S Calcineurin-like phosphoesterase
MFIHALKD_01598 1.3e-263 dtpT U amino acid peptide transporter
MFIHALKD_01599 3.7e-19
MFIHALKD_01601 4.7e-10
MFIHALKD_01602 6.2e-12
MFIHALKD_01603 1.9e-49 M KxYKxGKxW signal domain protein
MFIHALKD_01604 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_01605 1.8e-111 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MFIHALKD_01606 1.3e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MFIHALKD_01607 7.8e-51 S CRISPR-associated protein (Cas_Csn2)
MFIHALKD_01608 1.1e-18 L PFAM Integrase catalytic region
MFIHALKD_01609 4.3e-155 P Belongs to the nlpA lipoprotein family
MFIHALKD_01610 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFIHALKD_01611 1.4e-50 S Iron-sulfur cluster assembly protein
MFIHALKD_01612 1e-151
MFIHALKD_01613 3e-179
MFIHALKD_01614 6.5e-90 dut S Protein conserved in bacteria
MFIHALKD_01616 3.9e-12
MFIHALKD_01617 7.7e-219 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MFIHALKD_01618 2e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFIHALKD_01619 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
MFIHALKD_01620 4.1e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MFIHALKD_01621 5.9e-22 S Protein of unknown function (DUF3042)
MFIHALKD_01622 3.4e-67 yqhL P Rhodanese-like protein
MFIHALKD_01623 1.5e-183 glk 2.7.1.2 G Glucokinase
MFIHALKD_01624 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
MFIHALKD_01625 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
MFIHALKD_01626 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MFIHALKD_01627 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MFIHALKD_01628 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MFIHALKD_01629 0.0 S membrane
MFIHALKD_01630 3.7e-69 yneR S Belongs to the HesB IscA family
MFIHALKD_01631 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFIHALKD_01632 9.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
MFIHALKD_01633 5.1e-116 rlpA M PFAM NLP P60 protein
MFIHALKD_01634 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFIHALKD_01635 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFIHALKD_01636 6.7e-59 yodB K Transcriptional regulator, HxlR family
MFIHALKD_01637 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MFIHALKD_01638 2.2e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFIHALKD_01639 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MFIHALKD_01640 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFIHALKD_01641 7.4e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MFIHALKD_01642 2.3e-232 V MatE
MFIHALKD_01643 4.3e-267 yjeM E Amino Acid
MFIHALKD_01644 4.1e-278 arlS 2.7.13.3 T Histidine kinase
MFIHALKD_01645 1.5e-121 K response regulator
MFIHALKD_01646 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MFIHALKD_01647 8.4e-99 yceD S Uncharacterized ACR, COG1399
MFIHALKD_01648 1e-212 ylbM S Belongs to the UPF0348 family
MFIHALKD_01649 2.2e-139 yqeM Q Methyltransferase
MFIHALKD_01650 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MFIHALKD_01651 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MFIHALKD_01652 7.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MFIHALKD_01653 1.9e-47 yhbY J RNA-binding protein
MFIHALKD_01654 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
MFIHALKD_01655 1.3e-96 yqeG S HAD phosphatase, family IIIA
MFIHALKD_01656 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MFIHALKD_01657 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MFIHALKD_01658 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MFIHALKD_01659 8.1e-171 dnaI L Primosomal protein DnaI
MFIHALKD_01660 1.5e-202 dnaB L replication initiation and membrane attachment
MFIHALKD_01661 1.9e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFIHALKD_01662 1.5e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MFIHALKD_01663 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MFIHALKD_01664 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFIHALKD_01665 8.8e-119 yoaK S Protein of unknown function (DUF1275)
MFIHALKD_01666 1.9e-119 ybhL S Belongs to the BI1 family
MFIHALKD_01667 1.3e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MFIHALKD_01668 2.4e-20 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MFIHALKD_01669 1e-46 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MFIHALKD_01670 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFIHALKD_01671 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MFIHALKD_01672 7.5e-58 ytzB S Small secreted protein
MFIHALKD_01673 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
MFIHALKD_01674 4.6e-185 iolS C Aldo keto reductase
MFIHALKD_01675 3.9e-252 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MFIHALKD_01676 1.6e-295 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
MFIHALKD_01677 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MFIHALKD_01678 1.6e-216 ecsB U ABC transporter
MFIHALKD_01679 3e-136 ecsA V ABC transporter, ATP-binding protein
MFIHALKD_01680 8.3e-78 hit FG histidine triad
MFIHALKD_01682 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MFIHALKD_01683 0.0 L AAA domain
MFIHALKD_01684 1.1e-220 yhaO L Ser Thr phosphatase family protein
MFIHALKD_01685 9.4e-38 yheA S Belongs to the UPF0342 family
MFIHALKD_01686 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MFIHALKD_01687 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MFIHALKD_01688 1.6e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MFIHALKD_01689 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MFIHALKD_01691 3.3e-40
MFIHALKD_01692 1e-43
MFIHALKD_01693 2.8e-213 folP 2.5.1.15 H dihydropteroate synthase
MFIHALKD_01694 1.2e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
MFIHALKD_01695 9.7e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MFIHALKD_01696 1.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
MFIHALKD_01697 1e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MFIHALKD_01698 5.3e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MFIHALKD_01699 2.1e-72
MFIHALKD_01700 1.3e-142 S Domain of unknown function DUF1829
MFIHALKD_01701 4.3e-48
MFIHALKD_01703 1.9e-43
MFIHALKD_01704 3.2e-110 S CAAX protease self-immunity
MFIHALKD_01705 2.1e-32
MFIHALKD_01706 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFIHALKD_01707 1.1e-184 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
MFIHALKD_01708 5.9e-114
MFIHALKD_01709 1.5e-115 dck 2.7.1.74 F deoxynucleoside kinase
MFIHALKD_01710 3.3e-181 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFIHALKD_01711 1.9e-86 uspA T Belongs to the universal stress protein A family
MFIHALKD_01712 4.8e-276 pepV 3.5.1.18 E dipeptidase PepV
MFIHALKD_01713 6.3e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MFIHALKD_01714 1.5e-18 K Cro/C1-type HTH DNA-binding domain
MFIHALKD_01716 2.7e-28
MFIHALKD_01717 2e-29
MFIHALKD_01718 3.8e-256 ytgP S Polysaccharide biosynthesis protein
MFIHALKD_01719 1.4e-40
MFIHALKD_01720 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MFIHALKD_01721 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MFIHALKD_01722 1.1e-98 tag 3.2.2.20 L glycosylase
MFIHALKD_01723 2.4e-259 EGP Major facilitator Superfamily
MFIHALKD_01724 4.3e-85 perR P Belongs to the Fur family
MFIHALKD_01725 1.2e-231 cycA E Amino acid permease
MFIHALKD_01726 7e-101 V VanZ like family
MFIHALKD_01727 1e-23
MFIHALKD_01729 3.5e-91 S Uncharacterised protein family (UPF0236)
MFIHALKD_01730 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFIHALKD_01731 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MFIHALKD_01732 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFIHALKD_01733 5.1e-187 yegS 2.7.1.107 G Lipid kinase
MFIHALKD_01734 4.5e-12
MFIHALKD_01735 6.7e-34 doc S Fic/DOC family
MFIHALKD_01736 9.2e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFIHALKD_01737 6e-235
MFIHALKD_01738 6.3e-27 hsdM 2.1.1.72 V type I restriction-modification system
MFIHALKD_01739 2.8e-243 hsdM 2.1.1.72 V type I restriction-modification system
MFIHALKD_01740 1.4e-94 3.1.21.3 V Type I restriction modification DNA specificity domain
MFIHALKD_01741 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
MFIHALKD_01742 6.5e-87 entB 3.5.1.19 Q Isochorismatase family
MFIHALKD_01743 6.6e-85 K Bacterial regulatory proteins, tetR family
MFIHALKD_01744 5.7e-106 1.6.5.2 S NADPH-dependent FMN reductase
MFIHALKD_01745 3.3e-247 norB EGP Major Facilitator
MFIHALKD_01746 5.1e-82 padR K Transcriptional regulator PadR-like family
MFIHALKD_01748 9.7e-172 L Plasmid pRiA4b ORF-3-like protein
MFIHALKD_01749 4.2e-61 XK27_04080 H Riboflavin biosynthesis protein RibD
MFIHALKD_01750 4.2e-156 S PFAM Archaeal ATPase
MFIHALKD_01751 7.4e-47
MFIHALKD_01752 2.7e-85 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MFIHALKD_01753 1.2e-206 amtB P ammonium transporter
MFIHALKD_01754 1.6e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
MFIHALKD_01755 1.7e-91 S B3 4 domain
MFIHALKD_01756 8.1e-91
MFIHALKD_01757 4.8e-122 pnb C nitroreductase
MFIHALKD_01758 1.5e-74 ogt 2.1.1.63 L Methyltransferase
MFIHALKD_01759 1.1e-171 XK27_00915 C Luciferase-like monooxygenase
MFIHALKD_01760 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MFIHALKD_01761 4.7e-68 S Protein of unknown function (DUF3021)
MFIHALKD_01762 7e-77 K LytTr DNA-binding domain
MFIHALKD_01763 1.4e-21
MFIHALKD_01764 4.4e-206 yhjX P Major Facilitator Superfamily
MFIHALKD_01765 2.2e-120 ybhL S Belongs to the BI1 family
MFIHALKD_01766 2.1e-79 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
MFIHALKD_01767 1.3e-195 S Protein of unknown function (DUF3114)
MFIHALKD_01768 1.3e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MFIHALKD_01769 1.9e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MFIHALKD_01770 5.9e-111 yvdD 3.2.2.10 S Belongs to the LOG family
MFIHALKD_01771 9.1e-62 S Domain of unknown function (DUF4828)
MFIHALKD_01772 1e-190 mocA S Oxidoreductase
MFIHALKD_01773 6.7e-232 yfmL L DEAD DEAH box helicase
MFIHALKD_01775 1.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MFIHALKD_01776 2.3e-67 gtcA S Teichoic acid glycosylation protein
MFIHALKD_01777 6.1e-79 fld C Flavodoxin
MFIHALKD_01778 3.8e-167 map 3.4.11.18 E Methionine Aminopeptidase
MFIHALKD_01779 1e-220 arcT 2.6.1.1 E Aminotransferase
MFIHALKD_01780 1.7e-257 E Arginine ornithine antiporter
MFIHALKD_01781 1.8e-281 yjeM E Amino Acid
MFIHALKD_01782 8e-152 yihY S Belongs to the UPF0761 family
MFIHALKD_01783 1.9e-33 S Protein of unknown function (DUF2922)
MFIHALKD_01784 2.9e-31
MFIHALKD_01785 5.7e-141 recX 2.4.1.337 GT4 S Regulatory protein RecX
MFIHALKD_01786 3.7e-145 cps1D M Domain of unknown function (DUF4422)
MFIHALKD_01787 2.9e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MFIHALKD_01788 5.5e-118 rfbP 2.7.8.6 M Bacterial sugar transferase
MFIHALKD_01789 8.9e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
MFIHALKD_01790 4.3e-240 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
MFIHALKD_01791 3e-150 waaB GT4 M Glycosyl transferases group 1
MFIHALKD_01792 6.2e-132 M transferase activity, transferring glycosyl groups
MFIHALKD_01793 9.8e-96 acmD M repeat protein
MFIHALKD_01795 1.6e-103 S enterobacterial common antigen metabolic process
MFIHALKD_01796 1.3e-186 cps3F
MFIHALKD_01797 3.9e-84 M biosynthesis protein
MFIHALKD_01798 3.5e-91 S Uncharacterised protein family (UPF0236)
MFIHALKD_01799 6.1e-188 lacR K Transcriptional regulator
MFIHALKD_01800 0.0 lacS G Transporter
MFIHALKD_01801 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MFIHALKD_01802 9.3e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MFIHALKD_01803 7.5e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MFIHALKD_01804 6.7e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
MFIHALKD_01805 2.5e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
MFIHALKD_01806 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_01807 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MFIHALKD_01808 8.2e-224 mdtG EGP Major facilitator Superfamily
MFIHALKD_01809 4.9e-167 T Calcineurin-like phosphoesterase superfamily domain
MFIHALKD_01810 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFIHALKD_01812 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_01813 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_01816 7.5e-112 K Transcriptional regulator
MFIHALKD_01817 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
MFIHALKD_01818 7.4e-55 ysxB J Cysteine protease Prp
MFIHALKD_01819 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MFIHALKD_01820 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MFIHALKD_01821 5.4e-203 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MFIHALKD_01822 2.5e-113 J 2'-5' RNA ligase superfamily
MFIHALKD_01823 3.8e-70 yqhY S Asp23 family, cell envelope-related function
MFIHALKD_01824 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFIHALKD_01825 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFIHALKD_01826 9e-216 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFIHALKD_01827 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFIHALKD_01828 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MFIHALKD_01829 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MFIHALKD_01830 4.8e-76 argR K Regulates arginine biosynthesis genes
MFIHALKD_01831 2.8e-262 recN L May be involved in recombinational repair of damaged DNA
MFIHALKD_01832 1.7e-54
MFIHALKD_01833 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MFIHALKD_01834 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MFIHALKD_01835 1.8e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MFIHALKD_01836 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFIHALKD_01837 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MFIHALKD_01838 1.2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFIHALKD_01839 2.9e-131 stp 3.1.3.16 T phosphatase
MFIHALKD_01840 0.0 KLT serine threonine protein kinase
MFIHALKD_01841 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MFIHALKD_01842 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MFIHALKD_01843 7.7e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
MFIHALKD_01844 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MFIHALKD_01845 4.7e-58 asp S Asp23 family, cell envelope-related function
MFIHALKD_01846 0.0 yloV S DAK2 domain fusion protein YloV
MFIHALKD_01847 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MFIHALKD_01848 1.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MFIHALKD_01849 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFIHALKD_01850 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MFIHALKD_01851 0.0 smc D Required for chromosome condensation and partitioning
MFIHALKD_01852 5.9e-179 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MFIHALKD_01853 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MFIHALKD_01854 7.9e-250 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MFIHALKD_01855 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MFIHALKD_01856 4.1e-40 ylqC S Belongs to the UPF0109 family
MFIHALKD_01857 1.7e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MFIHALKD_01858 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MFIHALKD_01859 1.2e-261 yfnA E amino acid
MFIHALKD_01860 2.3e-63 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MFIHALKD_01861 1.4e-137 L Belongs to the 'phage' integrase family
MFIHALKD_01862 4e-45
MFIHALKD_01864 5.9e-21
MFIHALKD_01865 1.6e-14
MFIHALKD_01866 1.3e-10
MFIHALKD_01867 6.5e-64 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MFIHALKD_01868 7.7e-35
MFIHALKD_01869 3.9e-51 S Mazg nucleotide pyrophosphohydrolase
MFIHALKD_01870 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
MFIHALKD_01871 3.6e-82
MFIHALKD_01872 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MFIHALKD_01873 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_01875 8e-256 yjcE P Sodium proton antiporter
MFIHALKD_01876 3.6e-57
MFIHALKD_01878 8.8e-89
MFIHALKD_01879 0.0 copA 3.6.3.54 P P-type ATPase
MFIHALKD_01880 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MFIHALKD_01881 3.8e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MFIHALKD_01882 7.7e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MFIHALKD_01883 1e-162 EG EamA-like transporter family
MFIHALKD_01884 5.6e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
MFIHALKD_01885 5.8e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MFIHALKD_01886 2.3e-153 KT YcbB domain
MFIHALKD_01887 0.0 3.2.1.21 GH3 G hydrolase, family 3
MFIHALKD_01888 9.6e-299 xylB 2.7.1.17 G Belongs to the FGGY kinase family
MFIHALKD_01889 7.6e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MFIHALKD_01890 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
MFIHALKD_01891 9.7e-237 xynP G MFS/sugar transport protein
MFIHALKD_01892 3.1e-135 xylR GK ROK family
MFIHALKD_01893 0.0 3.2.1.55 GH51 G Right handed beta helix region
MFIHALKD_01894 4.8e-290 xynT G MFS/sugar transport protein
MFIHALKD_01895 1.7e-165 rhaS2 K Transcriptional regulator, AraC family
MFIHALKD_01896 2.1e-260 xylT EGP Major facilitator Superfamily
MFIHALKD_01898 2.5e-217 xylR GK ROK family
MFIHALKD_01899 1.3e-28
MFIHALKD_01900 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MFIHALKD_01901 1.3e-262 pgi 5.3.1.9 G Belongs to the GPI family
MFIHALKD_01902 1.5e-101 lacA 2.3.1.79 S Transferase hexapeptide repeat
MFIHALKD_01903 3.4e-155 glcU U sugar transport
MFIHALKD_01904 2.4e-273 yclK 2.7.13.3 T Histidine kinase
MFIHALKD_01905 7.9e-134 K response regulator
MFIHALKD_01907 2.8e-79 lytE M Lysin motif
MFIHALKD_01908 7e-147 XK27_02985 S Cof-like hydrolase
MFIHALKD_01909 2.3e-81 K Transcriptional regulator
MFIHALKD_01910 0.0 oatA I Acyltransferase
MFIHALKD_01911 8.7e-53
MFIHALKD_01912 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MFIHALKD_01913 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFIHALKD_01914 2e-126 ybbR S YbbR-like protein
MFIHALKD_01915 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFIHALKD_01916 4.8e-249 fucP G Major Facilitator Superfamily
MFIHALKD_01917 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MFIHALKD_01918 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFIHALKD_01919 3e-167 murB 1.3.1.98 M Cell wall formation
MFIHALKD_01920 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
MFIHALKD_01921 6.8e-77 S PAS domain
MFIHALKD_01922 2.6e-86 K Acetyltransferase (GNAT) domain
MFIHALKD_01923 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MFIHALKD_01924 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MFIHALKD_01925 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MFIHALKD_01926 4.8e-105 yxjI
MFIHALKD_01927 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MFIHALKD_01928 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MFIHALKD_01929 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
MFIHALKD_01930 1.8e-34 secG U Preprotein translocase
MFIHALKD_01931 1.2e-291 clcA P chloride
MFIHALKD_01932 7.1e-248 yifK E Amino acid permease
MFIHALKD_01933 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MFIHALKD_01934 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFIHALKD_01935 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MFIHALKD_01936 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFIHALKD_01938 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MFIHALKD_01939 2.6e-242 glpT G Major Facilitator Superfamily
MFIHALKD_01940 8.8e-15
MFIHALKD_01942 4e-170 whiA K May be required for sporulation
MFIHALKD_01943 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MFIHALKD_01944 2.2e-162 rapZ S Displays ATPase and GTPase activities
MFIHALKD_01945 2.4e-245 steT E amino acid
MFIHALKD_01946 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MFIHALKD_01947 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MFIHALKD_01948 1.5e-13
MFIHALKD_01949 2.3e-116 yfbR S HD containing hydrolase-like enzyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)