ORF_ID e_value Gene_name EC_number CAZy COGs Description
HLHEENCO_00001 1.2e-152 EG EamA-like transporter family
HLHEENCO_00002 2.5e-118 L Integrase
HLHEENCO_00003 1.4e-158 rssA S Phospholipase, patatin family
HLHEENCO_00004 2.6e-242 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HLHEENCO_00005 9.6e-200 xerS L Belongs to the 'phage' integrase family
HLHEENCO_00007 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLHEENCO_00008 4.2e-77 marR K Transcriptional regulator, MarR family
HLHEENCO_00009 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLHEENCO_00010 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLHEENCO_00011 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HLHEENCO_00012 4.2e-130 IQ reductase
HLHEENCO_00013 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLHEENCO_00014 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLHEENCO_00015 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLHEENCO_00016 6.8e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HLHEENCO_00017 7.7e-133 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLHEENCO_00018 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HLHEENCO_00019 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HLHEENCO_00024 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HLHEENCO_00025 3.3e-46 gcvH E glycine cleavage
HLHEENCO_00026 4.1e-220 rodA D Belongs to the SEDS family
HLHEENCO_00027 1e-31 S Protein of unknown function (DUF2969)
HLHEENCO_00028 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HLHEENCO_00029 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLHEENCO_00030 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HLHEENCO_00031 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HLHEENCO_00032 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLHEENCO_00033 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLHEENCO_00034 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLHEENCO_00035 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLHEENCO_00036 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLHEENCO_00037 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLHEENCO_00038 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HLHEENCO_00039 5e-232 pyrP F Permease
HLHEENCO_00040 6.3e-129 yibF S overlaps another CDS with the same product name
HLHEENCO_00041 9.9e-192 yibE S overlaps another CDS with the same product name
HLHEENCO_00042 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLHEENCO_00043 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLHEENCO_00044 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLHEENCO_00045 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLHEENCO_00046 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLHEENCO_00047 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLHEENCO_00048 6e-108 tdk 2.7.1.21 F thymidine kinase
HLHEENCO_00049 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HLHEENCO_00050 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HLHEENCO_00051 2.7e-223 arcD U Amino acid permease
HLHEENCO_00052 2e-261 E Arginine ornithine antiporter
HLHEENCO_00053 4.7e-79 argR K Regulates arginine biosynthesis genes
HLHEENCO_00054 4.1e-239 arcA 3.5.3.6 E Arginine
HLHEENCO_00055 3.9e-187 ampC V Beta-lactamase
HLHEENCO_00056 1.9e-32
HLHEENCO_00057 1.3e-260 S Putative peptidoglycan binding domain
HLHEENCO_00059 7.2e-79 2.7.13.3 T GHKL domain
HLHEENCO_00060 2.1e-55 S Protein of unknown function (DUF3290)
HLHEENCO_00061 6.9e-113 yviA S Protein of unknown function (DUF421)
HLHEENCO_00062 4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HLHEENCO_00063 1.3e-20
HLHEENCO_00064 8.1e-90 ntd 2.4.2.6 F Nucleoside
HLHEENCO_00065 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
HLHEENCO_00066 1.6e-45 yrvD S Pfam:DUF1049
HLHEENCO_00068 1.1e-35 S Phage derived protein Gp49-like (DUF891)
HLHEENCO_00069 8.5e-20 K Helix-turn-helix XRE-family like proteins
HLHEENCO_00070 1.7e-78 I alpha/beta hydrolase fold
HLHEENCO_00071 1.1e-113 frnE Q DSBA-like thioredoxin domain
HLHEENCO_00072 2e-53
HLHEENCO_00073 9.3e-189 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHEENCO_00074 4e-28 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHEENCO_00075 8.8e-77 yphH S Cupin domain
HLHEENCO_00076 4.2e-72 yeaL S UPF0756 membrane protein
HLHEENCO_00077 6.9e-243 EGP Major facilitator Superfamily
HLHEENCO_00078 5e-75 copY K Copper transport repressor CopY TcrY
HLHEENCO_00079 8.5e-246 yhdP S Transporter associated domain
HLHEENCO_00080 0.0 ubiB S ABC1 family
HLHEENCO_00081 9.6e-144 S DUF218 domain
HLHEENCO_00082 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLHEENCO_00083 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLHEENCO_00084 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLHEENCO_00085 0.0 uvrA3 L excinuclease ABC, A subunit
HLHEENCO_00086 4.6e-123 S SNARE associated Golgi protein
HLHEENCO_00087 1.3e-229 N Uncharacterized conserved protein (DUF2075)
HLHEENCO_00088 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLHEENCO_00090 1e-254 yifK E Amino acid permease
HLHEENCO_00091 5.5e-158 endA V DNA/RNA non-specific endonuclease
HLHEENCO_00092 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHEENCO_00093 6e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HLHEENCO_00094 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHEENCO_00095 2.4e-309 lmrA V ABC transporter, ATP-binding protein
HLHEENCO_00096 0.0 yfiC V ABC transporter
HLHEENCO_00097 1.1e-283 pipD E Dipeptidase
HLHEENCO_00098 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLHEENCO_00099 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
HLHEENCO_00100 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HLHEENCO_00101 2.7e-244 yagE E amino acid
HLHEENCO_00102 4.5e-140 aroD S Serine hydrolase (FSH1)
HLHEENCO_00103 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
HLHEENCO_00104 5.2e-167 GK ROK family
HLHEENCO_00105 0.0 tetP J elongation factor G
HLHEENCO_00106 5.1e-81 uspA T universal stress protein
HLHEENCO_00107 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
HLHEENCO_00108 7.1e-63
HLHEENCO_00109 5.2e-14
HLHEENCO_00110 1.4e-212 EGP Major facilitator Superfamily
HLHEENCO_00111 1.3e-257 G PTS system Galactitol-specific IIC component
HLHEENCO_00112 2.4e-167 1.6.5.5 C Zinc-binding dehydrogenase
HLHEENCO_00113 1.1e-161
HLHEENCO_00114 1e-72 K Transcriptional regulator
HLHEENCO_00115 8.2e-190 D Alpha beta
HLHEENCO_00116 2.2e-52 ypaA S Protein of unknown function (DUF1304)
HLHEENCO_00117 0.0 yjcE P Sodium proton antiporter
HLHEENCO_00118 1.6e-52 yvlA
HLHEENCO_00119 4.5e-112 P Cobalt transport protein
HLHEENCO_00120 1e-246 cbiO1 S ABC transporter, ATP-binding protein
HLHEENCO_00121 3e-96 S ABC-type cobalt transport system, permease component
HLHEENCO_00122 5.6e-133 S membrane transporter protein
HLHEENCO_00123 2.5e-138 IQ KR domain
HLHEENCO_00124 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HLHEENCO_00125 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HLHEENCO_00126 2.7e-149 L hmm pf00665
HLHEENCO_00127 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HLHEENCO_00128 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HLHEENCO_00129 2.8e-255 yagE E amino acid
HLHEENCO_00130 3.4e-85 dps P Belongs to the Dps family
HLHEENCO_00131 0.0 pacL 3.6.3.8 P P-type ATPase
HLHEENCO_00132 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HLHEENCO_00133 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLHEENCO_00134 1.7e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLHEENCO_00135 4.5e-146 potB P ABC transporter permease
HLHEENCO_00136 4.9e-140 potC P ABC transporter permease
HLHEENCO_00137 4.7e-207 potD P ABC transporter
HLHEENCO_00138 1.8e-108
HLHEENCO_00139 3.7e-43
HLHEENCO_00140 3.6e-233 EGP Sugar (and other) transporter
HLHEENCO_00141 3e-254 yfnA E Amino Acid
HLHEENCO_00142 2.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HLHEENCO_00143 5.8e-103 gmk2 2.7.4.8 F Guanylate kinase
HLHEENCO_00144 1.5e-82 zur P Belongs to the Fur family
HLHEENCO_00145 4e-17 3.2.1.14 GH18
HLHEENCO_00146 2e-152
HLHEENCO_00147 9.8e-39 pspC KT positive regulation of macromolecule biosynthetic process
HLHEENCO_00148 1.6e-94 K Transcriptional regulator (TetR family)
HLHEENCO_00149 3.2e-226 V domain protein
HLHEENCO_00150 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHEENCO_00152 6.6e-35 S Transglycosylase associated protein
HLHEENCO_00153 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLHEENCO_00154 4.2e-126 3.1.3.73 G phosphoglycerate mutase
HLHEENCO_00155 3.4e-115 dedA S SNARE associated Golgi protein
HLHEENCO_00156 0.0 helD 3.6.4.12 L DNA helicase
HLHEENCO_00157 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
HLHEENCO_00158 4.7e-157 EG EamA-like transporter family
HLHEENCO_00159 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLHEENCO_00160 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HLHEENCO_00161 1.5e-225 S cog cog1373
HLHEENCO_00163 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HLHEENCO_00164 4.9e-224 oxlT P Major Facilitator Superfamily
HLHEENCO_00165 1.1e-158 spoU 2.1.1.185 J Methyltransferase
HLHEENCO_00167 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
HLHEENCO_00168 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HLHEENCO_00169 1.8e-226 clcA_2 P Chloride transporter, ClC family
HLHEENCO_00170 4.4e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLHEENCO_00171 4.7e-85 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HLHEENCO_00172 8.3e-22 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HLHEENCO_00173 6.7e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLHEENCO_00174 5.2e-50
HLHEENCO_00175 0.0 S SEC-C Motif Domain Protein
HLHEENCO_00176 2.2e-09 L Transposase
HLHEENCO_00177 1.4e-72
HLHEENCO_00178 3.5e-24
HLHEENCO_00179 0.0 lacS G Transporter
HLHEENCO_00180 6.1e-39
HLHEENCO_00181 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLHEENCO_00182 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLHEENCO_00183 3.1e-193 yeaN P Transporter, major facilitator family protein
HLHEENCO_00184 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
HLHEENCO_00185 9.9e-85 nrdI F Belongs to the NrdI family
HLHEENCO_00186 6.2e-241 yhdP S Transporter associated domain
HLHEENCO_00187 1.7e-154 ypdB V (ABC) transporter
HLHEENCO_00188 4.8e-88 GM epimerase
HLHEENCO_00189 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
HLHEENCO_00190 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
HLHEENCO_00191 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
HLHEENCO_00192 2.8e-170 S AI-2E family transporter
HLHEENCO_00193 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HLHEENCO_00194 2.3e-162
HLHEENCO_00195 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HLHEENCO_00196 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HLHEENCO_00197 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLHEENCO_00198 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLHEENCO_00199 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLHEENCO_00200 3.5e-163 S Tetratricopeptide repeat
HLHEENCO_00201 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLHEENCO_00202 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLHEENCO_00203 1.1e-34 rpsT J Binds directly to 16S ribosomal RNA
HLHEENCO_00204 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
HLHEENCO_00205 0.0 comEC S Competence protein ComEC
HLHEENCO_00206 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
HLHEENCO_00207 2.6e-80 comEA L Competence protein ComEA
HLHEENCO_00208 4.3e-197 ylbL T Belongs to the peptidase S16 family
HLHEENCO_00209 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLHEENCO_00210 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HLHEENCO_00211 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HLHEENCO_00212 3.5e-222 ftsW D Belongs to the SEDS family
HLHEENCO_00213 0.0 typA T GTP-binding protein TypA
HLHEENCO_00214 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HLHEENCO_00215 1.4e-47 yktA S Belongs to the UPF0223 family
HLHEENCO_00216 1.2e-274 lpdA 1.8.1.4 C Dehydrogenase
HLHEENCO_00217 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLHEENCO_00218 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HLHEENCO_00219 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HLHEENCO_00220 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLHEENCO_00221 2.4e-78
HLHEENCO_00222 9.8e-32 ykzG S Belongs to the UPF0356 family
HLHEENCO_00223 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HLHEENCO_00224 5.7e-29
HLHEENCO_00225 3.2e-134 mltD CBM50 M NlpC P60 family protein
HLHEENCO_00227 7.7e-58
HLHEENCO_00228 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HLHEENCO_00229 2.2e-219 EG GntP family permease
HLHEENCO_00230 8.5e-84 KT Putative sugar diacid recognition
HLHEENCO_00231 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLHEENCO_00232 5.5e-217 patA 2.6.1.1 E Aminotransferase
HLHEENCO_00233 1.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLHEENCO_00234 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLHEENCO_00235 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLHEENCO_00236 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLHEENCO_00237 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLHEENCO_00238 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HLHEENCO_00239 1.9e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLHEENCO_00240 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLHEENCO_00241 3.4e-77 ctsR K Belongs to the CtsR family
HLHEENCO_00242 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HLHEENCO_00243 1.3e-16 S Hydrolases of the alpha beta superfamily
HLHEENCO_00244 4.8e-131 S Hydrolases of the alpha beta superfamily
HLHEENCO_00250 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HLHEENCO_00251 1.5e-275 lysP E amino acid
HLHEENCO_00252 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
HLHEENCO_00253 2.7e-120 lssY 3.6.1.27 I phosphatase
HLHEENCO_00254 6.7e-81 S Threonine/Serine exporter, ThrE
HLHEENCO_00255 3.6e-129 thrE S Putative threonine/serine exporter
HLHEENCO_00256 3.5e-31 cspC K Cold shock protein
HLHEENCO_00257 2.4e-124 sirR K iron dependent repressor
HLHEENCO_00258 6.5e-165 czcD P cation diffusion facilitator family transporter
HLHEENCO_00259 9.8e-169 L Transposase and inactivated derivatives IS30 family
HLHEENCO_00260 4.1e-37 S Uncharacterised protein family (UPF0236)
HLHEENCO_00261 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HLHEENCO_00262 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLHEENCO_00263 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLHEENCO_00264 3e-203 coiA 3.6.4.12 S Competence protein
HLHEENCO_00265 9.2e-264 pipD E Dipeptidase
HLHEENCO_00266 4.7e-114 yjbH Q Thioredoxin
HLHEENCO_00267 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HLHEENCO_00268 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLHEENCO_00269 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HLHEENCO_00270 4.1e-37 S Uncharacterised protein family (UPF0236)
HLHEENCO_00271 8.6e-59 lsa S ABC transporter
HLHEENCO_00272 7.5e-168 lsa S ABC transporter
HLHEENCO_00273 3.5e-134 I alpha/beta hydrolase fold
HLHEENCO_00274 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
HLHEENCO_00275 1.8e-220 G Belongs to the glycosyl hydrolase family 6
HLHEENCO_00276 1.3e-96 S NADPH-dependent FMN reductase
HLHEENCO_00277 7.4e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HLHEENCO_00278 2.6e-68 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HLHEENCO_00279 5.7e-82 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HLHEENCO_00280 3.1e-229 mntH P H( )-stimulated, divalent metal cation uptake system
HLHEENCO_00281 1.2e-81 Q Methyltransferase
HLHEENCO_00282 1.4e-116 ktrA P domain protein
HLHEENCO_00283 1.7e-238 ktrB P Potassium uptake protein
HLHEENCO_00284 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HLHEENCO_00285 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HLHEENCO_00286 4.8e-218 G Glycosyl hydrolases family 8
HLHEENCO_00287 2.2e-243 ydaM M Glycosyl transferase
HLHEENCO_00288 8e-141
HLHEENCO_00289 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHEENCO_00290 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HLHEENCO_00291 1.5e-25
HLHEENCO_00292 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
HLHEENCO_00293 7.2e-169 L transposase, IS605 OrfB family
HLHEENCO_00294 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
HLHEENCO_00295 1.3e-204 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HLHEENCO_00296 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLHEENCO_00297 1.9e-161 mleR K LysR family
HLHEENCO_00298 7.4e-305 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HLHEENCO_00299 1.4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLHEENCO_00300 1.8e-267 frdC 1.3.5.4 C FAD binding domain
HLHEENCO_00301 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
HLHEENCO_00302 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHEENCO_00303 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HLHEENCO_00304 5.3e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HLHEENCO_00305 0.0 ysaB V FtsX-like permease family
HLHEENCO_00306 2.1e-132 macB2 V ABC transporter, ATP-binding protein
HLHEENCO_00307 3.8e-179 T PhoQ Sensor
HLHEENCO_00308 1.7e-131 K response regulator
HLHEENCO_00309 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
HLHEENCO_00310 8.9e-136 pnuC H nicotinamide mononucleotide transporter
HLHEENCO_00311 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLHEENCO_00312 2.3e-204
HLHEENCO_00313 2.6e-52
HLHEENCO_00314 9.1e-36
HLHEENCO_00315 2.4e-92 yxkA S Phosphatidylethanolamine-binding protein
HLHEENCO_00316 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HLHEENCO_00317 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HLHEENCO_00318 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLHEENCO_00319 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HLHEENCO_00320 2e-180 galR K Transcriptional regulator
HLHEENCO_00321 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
HLHEENCO_00322 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLHEENCO_00323 1.5e-80 K AsnC family
HLHEENCO_00324 1.5e-80 uspA T universal stress protein
HLHEENCO_00325 1.1e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
HLHEENCO_00326 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHEENCO_00327 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLHEENCO_00328 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLHEENCO_00329 2.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
HLHEENCO_00330 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLHEENCO_00332 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLHEENCO_00333 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLHEENCO_00334 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HLHEENCO_00335 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HLHEENCO_00336 4.7e-243 codA 3.5.4.1 F cytosine deaminase
HLHEENCO_00337 3.1e-147 tesE Q hydratase
HLHEENCO_00338 4e-113 S (CBS) domain
HLHEENCO_00339 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLHEENCO_00340 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLHEENCO_00341 8.1e-39 yabO J S4 domain protein
HLHEENCO_00342 3.3e-56 divIC D Septum formation initiator
HLHEENCO_00343 9.8e-67 yabR J RNA binding
HLHEENCO_00344 9.3e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLHEENCO_00345 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HLHEENCO_00346 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLHEENCO_00347 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLHEENCO_00348 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLHEENCO_00349 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HLHEENCO_00350 5.5e-280 O Arylsulfotransferase (ASST)
HLHEENCO_00351 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHEENCO_00352 1.3e-08
HLHEENCO_00353 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLHEENCO_00354 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLHEENCO_00355 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLHEENCO_00356 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HLHEENCO_00357 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HLHEENCO_00358 7.8e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLHEENCO_00359 2.1e-87
HLHEENCO_00361 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLHEENCO_00362 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HLHEENCO_00363 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLHEENCO_00364 1.3e-35 ynzC S UPF0291 protein
HLHEENCO_00365 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HLHEENCO_00366 1e-116 plsC 2.3.1.51 I Acyltransferase
HLHEENCO_00367 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
HLHEENCO_00368 5.4e-49 yazA L GIY-YIG catalytic domain protein
HLHEENCO_00369 9.8e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHEENCO_00370 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HLHEENCO_00371 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLHEENCO_00372 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HLHEENCO_00373 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLHEENCO_00374 3.5e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLHEENCO_00375 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HLHEENCO_00376 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HLHEENCO_00377 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLHEENCO_00378 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLHEENCO_00379 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HLHEENCO_00380 6.8e-215 nusA K Participates in both transcription termination and antitermination
HLHEENCO_00381 1e-44 ylxR K Protein of unknown function (DUF448)
HLHEENCO_00382 4.5e-49 ylxQ J ribosomal protein
HLHEENCO_00383 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLHEENCO_00384 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLHEENCO_00385 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLHEENCO_00386 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HLHEENCO_00387 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHEENCO_00388 1e-159 mleR K LysR family
HLHEENCO_00389 2e-250 yjjP S Putative threonine/serine exporter
HLHEENCO_00390 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
HLHEENCO_00391 8.5e-282 emrY EGP Major facilitator Superfamily
HLHEENCO_00392 3.4e-188 I Alpha beta
HLHEENCO_00393 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HLHEENCO_00394 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLHEENCO_00396 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HLHEENCO_00397 2e-116 S Domain of unknown function (DUF4811)
HLHEENCO_00398 1e-268 lmrB EGP Major facilitator Superfamily
HLHEENCO_00399 4.9e-73 merR K MerR HTH family regulatory protein
HLHEENCO_00400 2.5e-53
HLHEENCO_00401 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLHEENCO_00402 1.5e-217 S CAAX protease self-immunity
HLHEENCO_00403 1.4e-108 glnP P ABC transporter permease
HLHEENCO_00404 4.2e-110 gluC P ABC transporter permease
HLHEENCO_00405 1.4e-150 glnH ET ABC transporter
HLHEENCO_00406 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLHEENCO_00407 5.5e-83 usp1 T Belongs to the universal stress protein A family
HLHEENCO_00408 8.4e-109 S VIT family
HLHEENCO_00409 1.6e-115 S membrane
HLHEENCO_00410 9.8e-169 L Transposase and inactivated derivatives IS30 family
HLHEENCO_00411 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HLHEENCO_00412 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLHEENCO_00413 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLHEENCO_00414 3.4e-35 nrdH O Glutaredoxin
HLHEENCO_00415 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLHEENCO_00416 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLHEENCO_00417 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLHEENCO_00418 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLHEENCO_00419 9.7e-39 S Protein of unknown function (DUF2508)
HLHEENCO_00420 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLHEENCO_00421 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HLHEENCO_00422 2.8e-185 holB 2.7.7.7 L DNA polymerase III
HLHEENCO_00423 5.9e-58 yabA L Involved in initiation control of chromosome replication
HLHEENCO_00424 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLHEENCO_00425 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
HLHEENCO_00426 7.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HLHEENCO_00427 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HLHEENCO_00428 1.8e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HLHEENCO_00429 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HLHEENCO_00430 3.1e-25
HLHEENCO_00431 1.2e-74 ntd 2.4.2.6 F Nucleoside
HLHEENCO_00444 4.3e-31 L NUMOD4 motif
HLHEENCO_00446 6.6e-75 dck 2.7.1.74 F deoxynucleoside kinase
HLHEENCO_00448 1.5e-17 S HNH endonuclease
HLHEENCO_00451 4.6e-101 L transposase, IS605 OrfB family
HLHEENCO_00455 8.5e-09 nrdH O Glutaredoxin
HLHEENCO_00456 3.1e-91 S nicotinamide riboside transmembrane transporter activity
HLHEENCO_00458 3.1e-78 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HLHEENCO_00461 2.2e-121 recD 3.1.11.5 L Helix-hairpin-helix containing domain
HLHEENCO_00464 7.2e-97 3.6.4.12 L DnaB-like helicase C terminal domain
HLHEENCO_00466 4.8e-31
HLHEENCO_00467 1.6e-61
HLHEENCO_00468 4.3e-21 L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLHEENCO_00469 7.4e-17
HLHEENCO_00471 1.5e-10 2.7.1.24 H dephospho-CoA kinase activity
HLHEENCO_00473 1.7e-81 L Belongs to the 'phage' integrase family
HLHEENCO_00475 3.5e-35
HLHEENCO_00476 3.7e-20 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLHEENCO_00481 3.8e-22
HLHEENCO_00482 3.3e-21 relB L Addiction module antitoxin, RelB DinJ family
HLHEENCO_00484 6.8e-09
HLHEENCO_00501 6e-14 ard S Antirestriction protein (ArdA)
HLHEENCO_00508 6.4e-35
HLHEENCO_00511 3.7e-71 D CobQ CobB MinD ParA nucleotide binding domain protein
HLHEENCO_00512 5.4e-17 S Replication initiator protein A (RepA) N-terminus
HLHEENCO_00517 1.1e-16
HLHEENCO_00518 1.1e-08 gp17a S Terminase-like family
HLHEENCO_00519 4.2e-25 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L Participates in initiation and elongation during chromosome replication
HLHEENCO_00520 2.7e-147 gp17a S Terminase-like family
HLHEENCO_00521 1.1e-34
HLHEENCO_00522 5.8e-50
HLHEENCO_00524 1.2e-60
HLHEENCO_00525 8.6e-154 tnpB L Putative transposase DNA-binding domain
HLHEENCO_00531 9e-28
HLHEENCO_00532 5.1e-31 GT2,GT4 O gp58-like protein
HLHEENCO_00533 1e-16
HLHEENCO_00535 1.3e-07
HLHEENCO_00537 1.4e-11 hol S COG5546 Small integral membrane protein
HLHEENCO_00540 4.7e-79 xerH L Belongs to the 'phage' integrase family
HLHEENCO_00541 2.5e-51 D Phage-related minor tail protein
HLHEENCO_00543 2.7e-52
HLHEENCO_00544 1.9e-67
HLHEENCO_00545 9.2e-106 fliC N bacterial-type flagellum-dependent cell motility
HLHEENCO_00546 3.6e-09
HLHEENCO_00549 3.8e-08
HLHEENCO_00550 3.7e-68 S regulation of transcription, DNA-dependent
HLHEENCO_00551 1.9e-112 S Glycosyl hydrolases family 25
HLHEENCO_00552 4.3e-70 S regulation of transcription, DNA-dependent
HLHEENCO_00553 6.5e-36 S DNA primase activity
HLHEENCO_00554 5.3e-42 S PD-(D/E)XK nuclease superfamily
HLHEENCO_00555 1.9e-27 S sequence-specific DNA binding transcription factor activity
HLHEENCO_00556 5.6e-227 dnaE_2 2.7.7.7 L DNA polymerase
HLHEENCO_00557 1.9e-85 L transposase, IS605 OrfB family
HLHEENCO_00559 8.2e-63 S DNA ligase (ATP) activity
HLHEENCO_00561 3e-31 S Protein of unknown function (DUF1064)
HLHEENCO_00569 2.6e-13
HLHEENCO_00573 8.8e-34 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HLHEENCO_00575 2e-50 tdk 2.7.1.21 F Thymidine kinase
HLHEENCO_00576 1.9e-32 lytE M LysM domain protein
HLHEENCO_00577 3.4e-82 L Integrase
HLHEENCO_00579 1.4e-282 V Type II restriction enzyme, methylase subunits
HLHEENCO_00586 6.2e-76 K Transcriptional regulator, TetR family
HLHEENCO_00587 2.2e-72
HLHEENCO_00588 4.8e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HLHEENCO_00589 7.9e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HLHEENCO_00590 2.4e-277 M domain protein
HLHEENCO_00591 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HLHEENCO_00592 3.8e-188 G Major Facilitator
HLHEENCO_00593 4.5e-49 G Major Facilitator
HLHEENCO_00594 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HLHEENCO_00595 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HLHEENCO_00596 3e-259 G Major Facilitator
HLHEENCO_00597 2.4e-181 K Transcriptional regulator, LacI family
HLHEENCO_00598 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLHEENCO_00600 1.2e-100 nqr 1.5.1.36 S reductase
HLHEENCO_00601 6.1e-198 XK27_09615 S reductase
HLHEENCO_00602 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLHEENCO_00603 1.4e-124 yciB M ErfK YbiS YcfS YnhG
HLHEENCO_00605 2.5e-101
HLHEENCO_00606 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HLHEENCO_00607 7.5e-123 S Alpha beta hydrolase
HLHEENCO_00608 1.7e-207 gldA 1.1.1.6 C dehydrogenase
HLHEENCO_00609 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLHEENCO_00610 1.3e-41
HLHEENCO_00611 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
HLHEENCO_00612 1.4e-284 S C4-dicarboxylate anaerobic carrier
HLHEENCO_00613 1.8e-251 nhaC C Na H antiporter NhaC
HLHEENCO_00614 1.6e-241 pbuX F xanthine permease
HLHEENCO_00615 1.4e-283 pipD E Dipeptidase
HLHEENCO_00616 7e-289 L Transposase
HLHEENCO_00617 8.2e-168 corA P CorA-like Mg2+ transporter protein
HLHEENCO_00618 2.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLHEENCO_00619 2.3e-131 terC P membrane
HLHEENCO_00620 2.1e-54 trxA O Belongs to the thioredoxin family
HLHEENCO_00621 1.6e-236 mepA V MATE efflux family protein
HLHEENCO_00622 4.2e-55 M Leucine-rich repeat (LRR) protein
HLHEENCO_00623 6.8e-56 K Transcriptional regulator, ArsR family
HLHEENCO_00624 1.2e-92 P Cadmium resistance transporter
HLHEENCO_00625 1.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
HLHEENCO_00626 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HLHEENCO_00627 2.2e-182 ABC-SBP S ABC transporter
HLHEENCO_00628 8.5e-73 M PFAM NLP P60 protein
HLHEENCO_00629 9.8e-169 L Transposase and inactivated derivatives IS30 family
HLHEENCO_00630 1.6e-52 azlD S branched-chain amino acid
HLHEENCO_00631 3.7e-136 azlC E AzlC protein
HLHEENCO_00632 4.2e-198 hpk31 2.7.13.3 T Histidine kinase
HLHEENCO_00633 1.2e-123 K response regulator
HLHEENCO_00634 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLHEENCO_00635 2.8e-171 deoR K sugar-binding domain protein
HLHEENCO_00636 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HLHEENCO_00637 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HLHEENCO_00638 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HLHEENCO_00639 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLHEENCO_00640 2.6e-135 XK27_01040 S Protein of unknown function (DUF1129)
HLHEENCO_00641 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLHEENCO_00642 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
HLHEENCO_00643 1.7e-154 spo0J K Belongs to the ParB family
HLHEENCO_00644 3.9e-139 soj D Sporulation initiation inhibitor
HLHEENCO_00645 4.3e-151 noc K Belongs to the ParB family
HLHEENCO_00646 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HLHEENCO_00647 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HLHEENCO_00648 5.6e-169 rihC 3.2.2.1 F Nucleoside
HLHEENCO_00649 2.3e-218 nupG F Nucleoside transporter
HLHEENCO_00650 7.2e-221 cycA E Amino acid permease
HLHEENCO_00652 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLHEENCO_00653 1.2e-264 glnP P ABC transporter
HLHEENCO_00654 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLHEENCO_00655 4.5e-160 L hmm pf00665
HLHEENCO_00656 4.4e-100 L Helix-turn-helix domain
HLHEENCO_00657 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLHEENCO_00658 7.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HLHEENCO_00659 8.1e-114 rlpA M PFAM NLP P60 protein
HLHEENCO_00660 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLHEENCO_00661 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLHEENCO_00662 2e-58 yodB K Transcriptional regulator, HxlR family
HLHEENCO_00663 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLHEENCO_00664 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLHEENCO_00665 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HLHEENCO_00666 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLHEENCO_00667 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLHEENCO_00668 4.4e-231 V MatE
HLHEENCO_00669 7.4e-267 yjeM E Amino Acid
HLHEENCO_00670 4.1e-278 arlS 2.7.13.3 T Histidine kinase
HLHEENCO_00671 1.5e-121 K response regulator
HLHEENCO_00672 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HLHEENCO_00673 2.9e-99 yceD S Uncharacterized ACR, COG1399
HLHEENCO_00674 6.1e-213 ylbM S Belongs to the UPF0348 family
HLHEENCO_00675 1.7e-139 yqeM Q Methyltransferase
HLHEENCO_00676 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLHEENCO_00677 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HLHEENCO_00678 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLHEENCO_00679 1.9e-47 yhbY J RNA-binding protein
HLHEENCO_00680 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
HLHEENCO_00681 1.8e-95 yqeG S HAD phosphatase, family IIIA
HLHEENCO_00682 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLHEENCO_00683 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HLHEENCO_00684 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLHEENCO_00685 1.1e-170 dnaI L Primosomal protein DnaI
HLHEENCO_00686 1.4e-203 dnaB L replication initiation and membrane attachment
HLHEENCO_00687 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLHEENCO_00688 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLHEENCO_00689 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLHEENCO_00690 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLHEENCO_00691 4.1e-116 yoaK S Protein of unknown function (DUF1275)
HLHEENCO_00692 1.9e-119 ybhL S Belongs to the BI1 family
HLHEENCO_00693 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HLHEENCO_00694 1.5e-35 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HLHEENCO_00695 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HLHEENCO_00696 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLHEENCO_00697 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HLHEENCO_00698 7.5e-58 ytzB S Small secreted protein
HLHEENCO_00699 2.6e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
HLHEENCO_00700 1.1e-183 iolS C Aldo keto reductase
HLHEENCO_00701 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HLHEENCO_00702 6.7e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HLHEENCO_00703 4e-254 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HLHEENCO_00704 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HLHEENCO_00705 7.7e-27 S YSIRK type signal peptide
HLHEENCO_00706 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLHEENCO_00707 5.1e-218 ecsB U ABC transporter
HLHEENCO_00708 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HLHEENCO_00709 1.2e-76 hit FG histidine triad
HLHEENCO_00711 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLHEENCO_00712 0.0 L AAA domain
HLHEENCO_00713 1.8e-220 yhaO L Ser Thr phosphatase family protein
HLHEENCO_00714 3.5e-40 yheA S Belongs to the UPF0342 family
HLHEENCO_00715 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HLHEENCO_00716 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HLHEENCO_00717 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HLHEENCO_00718 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HLHEENCO_00720 3.3e-40
HLHEENCO_00721 1.8e-43
HLHEENCO_00722 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
HLHEENCO_00723 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HLHEENCO_00724 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HLHEENCO_00725 1.2e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HLHEENCO_00726 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HLHEENCO_00727 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLHEENCO_00729 1.9e-43
HLHEENCO_00730 2.6e-118 S CAAX protease self-immunity
HLHEENCO_00731 2.1e-32
HLHEENCO_00732 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLHEENCO_00733 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HLHEENCO_00734 3.8e-113
HLHEENCO_00735 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HLHEENCO_00736 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLHEENCO_00737 1.2e-85 uspA T Belongs to the universal stress protein A family
HLHEENCO_00738 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
HLHEENCO_00739 2.2e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLHEENCO_00740 9.2e-303 ytgP S Polysaccharide biosynthesis protein
HLHEENCO_00741 4.9e-41
HLHEENCO_00742 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLHEENCO_00743 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLHEENCO_00744 9.6e-92 tag 3.2.2.20 L glycosylase
HLHEENCO_00746 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HLHEENCO_00747 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
HLHEENCO_00748 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLHEENCO_00749 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HLHEENCO_00750 1.2e-10 S Protein of unknown function (DUF4044)
HLHEENCO_00751 7.3e-56
HLHEENCO_00752 3.1e-77 mraZ K Belongs to the MraZ family
HLHEENCO_00753 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLHEENCO_00754 2.6e-56 ftsL D Cell division protein FtsL
HLHEENCO_00755 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HLHEENCO_00756 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLHEENCO_00757 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLHEENCO_00758 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLHEENCO_00759 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLHEENCO_00760 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLHEENCO_00761 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLHEENCO_00762 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLHEENCO_00763 3.2e-40 yggT S YGGT family
HLHEENCO_00764 5.1e-142 ylmH S S4 domain protein
HLHEENCO_00765 1.9e-42 divIVA D DivIVA domain protein
HLHEENCO_00766 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLHEENCO_00767 4.2e-32 cspA K Cold shock protein
HLHEENCO_00768 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HLHEENCO_00770 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLHEENCO_00771 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
HLHEENCO_00772 3.7e-57 XK27_04120 S Putative amino acid metabolism
HLHEENCO_00773 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLHEENCO_00774 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HLHEENCO_00775 2.6e-118 S Repeat protein
HLHEENCO_00776 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLHEENCO_00777 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLHEENCO_00779 4.4e-100 L Helix-turn-helix domain
HLHEENCO_00780 4.5e-160 L hmm pf00665
HLHEENCO_00781 5.9e-114 L PFAM Integrase catalytic region
HLHEENCO_00782 1.6e-67 yqkB S Belongs to the HesB IscA family
HLHEENCO_00783 2.7e-49
HLHEENCO_00785 3.5e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HLHEENCO_00786 1.3e-61 asp S Asp23 family, cell envelope-related function
HLHEENCO_00787 2.1e-25
HLHEENCO_00788 3.2e-95
HLHEENCO_00789 7e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HLHEENCO_00790 9.9e-183 K Transcriptional regulator, LacI family
HLHEENCO_00791 4.9e-160 gntT EG Gluconate
HLHEENCO_00792 3e-39 gntT EG Gluconate
HLHEENCO_00793 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HLHEENCO_00794 2.9e-96 K Acetyltransferase (GNAT) domain
HLHEENCO_00795 5.4e-47
HLHEENCO_00796 2.4e-22
HLHEENCO_00797 2.2e-44
HLHEENCO_00798 4.1e-57 yhaI S Protein of unknown function (DUF805)
HLHEENCO_00799 6.1e-301 2.1.1.72 V type I restriction-modification system
HLHEENCO_00800 1.1e-26 3.1.21.3 V Type I restriction modification DNA specificity domain
HLHEENCO_00801 1.4e-39 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction
HLHEENCO_00802 2.1e-177 xerC L Belongs to the 'phage' integrase family
HLHEENCO_00803 4.3e-61 3.1.21.3 V type I restriction modification DNA specificity domain
HLHEENCO_00804 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HLHEENCO_00805 0.0 L PLD-like domain
HLHEENCO_00807 2.1e-60 L PFAM transposase IS200-family protein
HLHEENCO_00808 7.4e-230 L transposase, IS605 OrfB family
HLHEENCO_00809 5.9e-114 L PFAM Integrase catalytic region
HLHEENCO_00810 7e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HLHEENCO_00811 1.2e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HLHEENCO_00812 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLHEENCO_00813 1.8e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLHEENCO_00814 7.3e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLHEENCO_00815 1.2e-135 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLHEENCO_00816 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HLHEENCO_00817 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
HLHEENCO_00818 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLHEENCO_00819 0.0 uup S ABC transporter, ATP-binding protein
HLHEENCO_00820 5.9e-114 L PFAM Integrase catalytic region
HLHEENCO_00821 3.3e-83
HLHEENCO_00822 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HLHEENCO_00823 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
HLHEENCO_00824 2.9e-34
HLHEENCO_00825 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLHEENCO_00826 9.9e-261 yfnA E amino acid
HLHEENCO_00827 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HLHEENCO_00828 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLHEENCO_00829 1.3e-38 ylqC S Belongs to the UPF0109 family
HLHEENCO_00830 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HLHEENCO_00831 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLHEENCO_00832 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLHEENCO_00833 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLHEENCO_00834 0.0 smc D Required for chromosome condensation and partitioning
HLHEENCO_00835 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLHEENCO_00836 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLHEENCO_00837 6.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLHEENCO_00838 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLHEENCO_00839 7.1e-311 yloV S DAK2 domain fusion protein YloV
HLHEENCO_00840 4.7e-58 asp S Asp23 family, cell envelope-related function
HLHEENCO_00841 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HLHEENCO_00842 1.6e-114 thiN 2.7.6.2 H thiamine pyrophosphokinase
HLHEENCO_00843 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HLHEENCO_00844 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLHEENCO_00845 0.0 KLT serine threonine protein kinase
HLHEENCO_00846 3.8e-131 stp 3.1.3.16 T phosphatase
HLHEENCO_00847 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLHEENCO_00848 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLHEENCO_00849 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLHEENCO_00850 1.2e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLHEENCO_00851 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLHEENCO_00852 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HLHEENCO_00853 2.4e-53
HLHEENCO_00854 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
HLHEENCO_00855 8.1e-76 argR K Regulates arginine biosynthesis genes
HLHEENCO_00856 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HLHEENCO_00857 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLHEENCO_00858 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLHEENCO_00859 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLHEENCO_00860 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLHEENCO_00861 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLHEENCO_00862 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HLHEENCO_00863 1.9e-113 J 2'-5' RNA ligase superfamily
HLHEENCO_00864 5.1e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HLHEENCO_00865 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLHEENCO_00866 1.8e-93 M Glycosyl hydrolases family 25
HLHEENCO_00867 1e-24 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HLHEENCO_00868 3.8e-34
HLHEENCO_00869 0.0 cotH M CotH kinase protein
HLHEENCO_00872 1.8e-61 M Prophage endopeptidase tail
HLHEENCO_00873 2e-69 S Phage tail protein
HLHEENCO_00874 7.4e-86 dnaG S Transglycosylase SLT domain
HLHEENCO_00875 1.3e-29 S Bacteriophage Gp15 protein
HLHEENCO_00877 2e-38 N domain, Protein
HLHEENCO_00878 2.2e-16 S Minor capsid protein from bacteriophage
HLHEENCO_00879 3.9e-11 S Minor capsid protein
HLHEENCO_00880 4e-30 S Minor capsid protein
HLHEENCO_00881 3.2e-13
HLHEENCO_00882 4.8e-101
HLHEENCO_00883 1.8e-19 S Phage minor structural protein GP20
HLHEENCO_00884 4.1e-92 S Phage minor capsid protein 2
HLHEENCO_00885 1.2e-134 S Phage portal protein, SPP1 Gp6-like
HLHEENCO_00886 2.8e-23 L HNH endonuclease
HLHEENCO_00887 2.5e-138 S Pfam:Terminase_3C
HLHEENCO_00888 7.4e-22
HLHEENCO_00889 1.1e-33
HLHEENCO_00892 2.2e-28 rusA L Endodeoxyribonuclease RusA
HLHEENCO_00893 1e-105 L Helix-turn-helix domain
HLHEENCO_00894 3.9e-140 L hmm pf00665
HLHEENCO_00895 5.9e-114 L PFAM Integrase catalytic region
HLHEENCO_00896 2.8e-35
HLHEENCO_00897 9.3e-62 K DNA-templated transcription, initiation
HLHEENCO_00898 3e-41 K Transcriptional regulator, HxlR family
HLHEENCO_00899 2.4e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HLHEENCO_00900 3.8e-146 epsB M biosynthesis protein
HLHEENCO_00901 8.7e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HLHEENCO_00902 8.9e-116 rfbP M Bacterial sugar transferase
HLHEENCO_00903 3.7e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLHEENCO_00904 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLHEENCO_00905 2e-194 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLHEENCO_00906 1.8e-184 M family 8
HLHEENCO_00907 5.4e-181 GT2 M Glycosyltransferase like family 2
HLHEENCO_00908 7.5e-183 M Glycosyl transferase, family 2
HLHEENCO_00909 7.8e-233 S Psort location CytoplasmicMembrane, score 9.99
HLHEENCO_00910 3e-238 S polysaccharide biosynthetic process
HLHEENCO_00911 1.3e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
HLHEENCO_00912 6.6e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLHEENCO_00913 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLHEENCO_00914 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLHEENCO_00915 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLHEENCO_00916 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HLHEENCO_00917 6.5e-202 ykiI
HLHEENCO_00918 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHEENCO_00919 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHEENCO_00920 1e-110 K Bacterial regulatory proteins, tetR family
HLHEENCO_00921 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHEENCO_00922 3.2e-83 F Belongs to the NrdI family
HLHEENCO_00923 1.2e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HLHEENCO_00924 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
HLHEENCO_00925 1.5e-65 esbA S Family of unknown function (DUF5322)
HLHEENCO_00926 1.3e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLHEENCO_00927 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLHEENCO_00928 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
HLHEENCO_00929 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HLHEENCO_00930 0.0 FbpA K Fibronectin-binding protein
HLHEENCO_00931 1.9e-161 degV S EDD domain protein, DegV family
HLHEENCO_00932 1.1e-92
HLHEENCO_00933 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLHEENCO_00934 1.1e-158 gspA M family 8
HLHEENCO_00935 1.2e-160 S Alpha beta hydrolase
HLHEENCO_00936 7.6e-94 K Acetyltransferase (GNAT) domain
HLHEENCO_00937 1.1e-240 XK27_08635 S UPF0210 protein
HLHEENCO_00938 2.1e-39 gcvR T Belongs to the UPF0237 family
HLHEENCO_00939 5.9e-163 1.1.1.346 C Aldo keto reductase
HLHEENCO_00940 1.1e-60 K LysR substrate binding domain protein
HLHEENCO_00941 1.5e-80 C Flavodoxin
HLHEENCO_00949 1.2e-141 L Belongs to the 'phage' integrase family
HLHEENCO_00950 9.3e-121 S Domain of unknown function (DUF5067)
HLHEENCO_00951 7.1e-72
HLHEENCO_00953 2.7e-58 K Transcriptional regulator, Cro CI family
HLHEENCO_00954 1.8e-30 K Helix-turn-helix XRE-family like proteins
HLHEENCO_00955 8.8e-118 K ORF6N domain
HLHEENCO_00956 3.5e-36
HLHEENCO_00959 8.4e-31
HLHEENCO_00961 2.8e-82 S Siphovirus Gp157
HLHEENCO_00962 2.5e-08
HLHEENCO_00963 3.4e-258 res L Helicase C-terminal domain protein
HLHEENCO_00964 9.3e-141 L AAA domain
HLHEENCO_00965 1.7e-93
HLHEENCO_00966 4.2e-144 S Bifunctional DNA primase/polymerase, N-terminal
HLHEENCO_00967 2.2e-224 S Virulence-associated protein E
HLHEENCO_00969 1.3e-32 S VRR_NUC
HLHEENCO_00971 1.4e-10
HLHEENCO_00976 1.9e-72 arpU S Phage transcriptional regulator, ArpU family
HLHEENCO_00977 1.8e-61 L Terminase small subunit
HLHEENCO_00978 4.4e-09 S Phage terminase, large subunit
HLHEENCO_00979 9.7e-222 S Phage terminase, large subunit
HLHEENCO_00980 9.5e-272 S Phage portal protein
HLHEENCO_00981 4.1e-238 S Phage Mu protein F like protein
HLHEENCO_00983 6.3e-33 S YjcQ protein
HLHEENCO_00984 7.7e-102 S Domain of unknown function (DUF4355)
HLHEENCO_00985 2.9e-154
HLHEENCO_00986 2.1e-64 S Phage gp6-like head-tail connector protein
HLHEENCO_00987 1.3e-43
HLHEENCO_00988 3.6e-67 S Bacteriophage HK97-gp10, putative tail-component
HLHEENCO_00989 3.4e-22 S Protein of unknown function (DUF3168)
HLHEENCO_00990 9.1e-104 S Phage tail tube protein
HLHEENCO_00991 4.2e-53 S Phage tail assembly chaperone protein, TAC
HLHEENCO_00992 2.7e-61
HLHEENCO_00993 1.3e-255 sca1 D Phage tail tape measure protein
HLHEENCO_00994 6.1e-148 S phage tail
HLHEENCO_00995 0.0 M Prophage endopeptidase tail
HLHEENCO_00997 0.0 cotH M CotH kinase protein
HLHEENCO_00999 1e-26
HLHEENCO_01000 1.3e-56 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HLHEENCO_01001 3.5e-181 3.5.1.104 M hydrolase, family 25
HLHEENCO_01002 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
HLHEENCO_01003 1.5e-237 lmrB EGP Major facilitator Superfamily
HLHEENCO_01004 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HLHEENCO_01005 1.7e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLHEENCO_01006 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
HLHEENCO_01007 2.6e-80 lytE M LysM domain protein
HLHEENCO_01008 0.0 oppD EP Psort location Cytoplasmic, score
HLHEENCO_01009 2.3e-93 lytE M LysM domain protein
HLHEENCO_01010 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
HLHEENCO_01011 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HLHEENCO_01012 1.2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
HLHEENCO_01013 8.1e-154 yeaE S Aldo keto
HLHEENCO_01014 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HLHEENCO_01015 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HLHEENCO_01016 2.9e-78 S Psort location Cytoplasmic, score
HLHEENCO_01017 7.7e-86 S Short repeat of unknown function (DUF308)
HLHEENCO_01018 1e-23
HLHEENCO_01019 2.8e-102 V VanZ like family
HLHEENCO_01020 4.8e-233 cycA E Amino acid permease
HLHEENCO_01021 4.3e-85 perR P Belongs to the Fur family
HLHEENCO_01022 1.5e-253 EGP Major facilitator Superfamily
HLHEENCO_01023 9.8e-169 L Transposase and inactivated derivatives IS30 family
HLHEENCO_01024 8.2e-48
HLHEENCO_01025 7.8e-272 S ABC transporter, ATP-binding protein
HLHEENCO_01026 2.3e-142 S Putative ABC-transporter type IV
HLHEENCO_01027 2e-106 NU mannosyl-glycoprotein
HLHEENCO_01028 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
HLHEENCO_01029 3.3e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
HLHEENCO_01030 7.6e-205 nrnB S DHHA1 domain
HLHEENCO_01032 6.9e-49
HLHEENCO_01033 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HLHEENCO_01034 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HLHEENCO_01035 2e-15 S Domain of unknown function (DUF4767)
HLHEENCO_01036 9.5e-55
HLHEENCO_01037 2.9e-117 yrkL S Flavodoxin-like fold
HLHEENCO_01039 1.6e-64 yeaO S Protein of unknown function, DUF488
HLHEENCO_01040 6.3e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HLHEENCO_01041 3e-204 3.1.3.1 S associated with various cellular activities
HLHEENCO_01042 9.3e-242 S Putative metallopeptidase domain
HLHEENCO_01043 5.1e-47
HLHEENCO_01044 0.0 pepO 3.4.24.71 O Peptidase family M13
HLHEENCO_01045 3.2e-110 K Helix-turn-helix domain
HLHEENCO_01046 5.6e-86 ymdB S Macro domain protein
HLHEENCO_01047 2.1e-197 EGP Major facilitator Superfamily
HLHEENCO_01048 4.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHEENCO_01049 1e-105 L Helix-turn-helix domain
HLHEENCO_01050 3.9e-140 L hmm pf00665
HLHEENCO_01051 3.3e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HLHEENCO_01052 1e-105 L Helix-turn-helix domain
HLHEENCO_01053 3.9e-140 L hmm pf00665
HLHEENCO_01054 2.3e-16
HLHEENCO_01056 5.6e-52 S ORF6C domain
HLHEENCO_01059 2.2e-54
HLHEENCO_01060 9.9e-51 L Psort location Cytoplasmic, score
HLHEENCO_01061 9.4e-149 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HLHEENCO_01062 1.4e-159 recT L RecT family
HLHEENCO_01066 2.8e-28
HLHEENCO_01071 1.2e-13
HLHEENCO_01072 1.3e-48 ps115 K Helix-turn-helix XRE-family like proteins
HLHEENCO_01073 2.1e-20 E Zn peptidase
HLHEENCO_01074 2e-35 S Membrane
HLHEENCO_01076 4.5e-49
HLHEENCO_01077 2.6e-208 L Belongs to the 'phage' integrase family
HLHEENCO_01078 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HLHEENCO_01079 1.6e-54 ysxB J Cysteine protease Prp
HLHEENCO_01080 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HLHEENCO_01081 1.8e-110 K Transcriptional regulator
HLHEENCO_01084 7.2e-89 dut S Protein conserved in bacteria
HLHEENCO_01085 6.6e-174
HLHEENCO_01086 1e-151
HLHEENCO_01087 3.7e-51 S Iron-sulfur cluster assembly protein
HLHEENCO_01088 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLHEENCO_01089 1.7e-146 P Belongs to the nlpA lipoprotein family
HLHEENCO_01090 3.9e-12
HLHEENCO_01091 6.3e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HLHEENCO_01092 3.8e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLHEENCO_01093 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
HLHEENCO_01094 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLHEENCO_01095 1.3e-21 S Protein of unknown function (DUF3042)
HLHEENCO_01096 3.4e-67 yqhL P Rhodanese-like protein
HLHEENCO_01097 5.6e-183 glk 2.7.1.2 G Glucokinase
HLHEENCO_01098 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HLHEENCO_01099 1.4e-26 gluP 3.4.21.105 S Peptidase, S54 family
HLHEENCO_01100 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
HLHEENCO_01101 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLHEENCO_01102 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HLHEENCO_01103 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HLHEENCO_01104 0.0 S membrane
HLHEENCO_01105 8.8e-71 yneR S Belongs to the HesB IscA family
HLHEENCO_01106 1.6e-38 L PFAM transposase IS200-family protein
HLHEENCO_01107 3.9e-140 L hmm pf00665
HLHEENCO_01108 1e-105 L Helix-turn-helix domain
HLHEENCO_01109 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLHEENCO_01110 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HLHEENCO_01111 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HLHEENCO_01112 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HLHEENCO_01113 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
HLHEENCO_01114 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
HLHEENCO_01115 2.8e-207 araR K Transcriptional regulator
HLHEENCO_01116 3.5e-35
HLHEENCO_01117 2.5e-212 bacI V MacB-like periplasmic core domain
HLHEENCO_01118 7.7e-126 V ABC transporter
HLHEENCO_01119 9.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLHEENCO_01120 2.3e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HLHEENCO_01121 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLHEENCO_01122 2.7e-148 E Glyoxalase-like domain
HLHEENCO_01123 7.5e-155 glcU U sugar transport
HLHEENCO_01124 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HLHEENCO_01125 2.2e-96 S reductase
HLHEENCO_01126 1.4e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLHEENCO_01127 1.7e-179 ABC-SBP S ABC transporter
HLHEENCO_01128 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HLHEENCO_01129 2.5e-215 htrA 3.4.21.107 O serine protease
HLHEENCO_01130 4.5e-154 vicX 3.1.26.11 S domain protein
HLHEENCO_01131 2.7e-149 yycI S YycH protein
HLHEENCO_01132 2.1e-246 yycH S YycH protein
HLHEENCO_01133 0.0 vicK 2.7.13.3 T Histidine kinase
HLHEENCO_01134 6.8e-130 K response regulator
HLHEENCO_01136 5.2e-309 lmrA 3.6.3.44 V ABC transporter
HLHEENCO_01137 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
HLHEENCO_01139 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLHEENCO_01140 5.5e-40 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLHEENCO_01141 8.4e-156 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLHEENCO_01142 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
HLHEENCO_01143 1.1e-90 bioY S BioY family
HLHEENCO_01144 1.5e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLHEENCO_01145 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
HLHEENCO_01146 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLHEENCO_01147 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HLHEENCO_01148 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLHEENCO_01149 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
HLHEENCO_01150 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HLHEENCO_01151 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HLHEENCO_01152 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLHEENCO_01153 1.9e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLHEENCO_01154 1.2e-219 patA 2.6.1.1 E Aminotransferase
HLHEENCO_01155 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
HLHEENCO_01156 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLHEENCO_01157 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HLHEENCO_01158 3e-30 S Protein of unknown function (DUF2929)
HLHEENCO_01159 0.0 dnaE 2.7.7.7 L DNA polymerase
HLHEENCO_01160 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HLHEENCO_01161 2.3e-167 cvfB S S1 domain
HLHEENCO_01162 1.2e-163 xerD D recombinase XerD
HLHEENCO_01163 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLHEENCO_01164 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLHEENCO_01165 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLHEENCO_01166 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLHEENCO_01167 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLHEENCO_01168 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
HLHEENCO_01169 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HLHEENCO_01170 8.5e-14 M Lysin motif
HLHEENCO_01171 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HLHEENCO_01172 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HLHEENCO_01173 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HLHEENCO_01174 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLHEENCO_01175 1.5e-236 S Tetratricopeptide repeat protein
HLHEENCO_01176 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLHEENCO_01177 0.0 yfmR S ABC transporter, ATP-binding protein
HLHEENCO_01178 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLHEENCO_01179 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLHEENCO_01180 5.3e-113 hlyIII S protein, hemolysin III
HLHEENCO_01181 1.7e-151 DegV S EDD domain protein, DegV family
HLHEENCO_01182 9.5e-172 ypmR E lipolytic protein G-D-S-L family
HLHEENCO_01183 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HLHEENCO_01184 4.4e-35 yozE S Belongs to the UPF0346 family
HLHEENCO_01185 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLHEENCO_01186 7.9e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLHEENCO_01187 2.4e-161 dprA LU DNA protecting protein DprA
HLHEENCO_01188 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLHEENCO_01189 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
HLHEENCO_01190 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLHEENCO_01191 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLHEENCO_01192 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLHEENCO_01193 1.7e-84 F NUDIX domain
HLHEENCO_01194 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HLHEENCO_01195 1.8e-09
HLHEENCO_01197 1e-44
HLHEENCO_01198 2e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HLHEENCO_01199 3.4e-250 mmuP E amino acid
HLHEENCO_01201 2.1e-60 L PFAM transposase IS200-family protein
HLHEENCO_01202 7.4e-230 L transposase, IS605 OrfB family
HLHEENCO_01203 6.1e-54 trxA O Belongs to the thioredoxin family
HLHEENCO_01204 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLHEENCO_01205 1e-85 cvpA S Colicin V production protein
HLHEENCO_01206 6.1e-48 yrzB S Belongs to the UPF0473 family
HLHEENCO_01207 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLHEENCO_01208 4.1e-43 yrzL S Belongs to the UPF0297 family
HLHEENCO_01209 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLHEENCO_01210 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLHEENCO_01211 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HLHEENCO_01212 2.8e-31 yajC U Preprotein translocase
HLHEENCO_01213 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLHEENCO_01214 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLHEENCO_01215 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLHEENCO_01216 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLHEENCO_01217 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLHEENCO_01218 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HLHEENCO_01219 4.1e-37 S Uncharacterised protein family (UPF0236)
HLHEENCO_01220 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HLHEENCO_01221 6.4e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLHEENCO_01222 1e-170 M Glycosyl hydrolases family 25
HLHEENCO_01223 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
HLHEENCO_01224 0.0 snf 2.7.11.1 KL domain protein
HLHEENCO_01225 6.7e-07 D nuclear chromosome segregation
HLHEENCO_01226 8.9e-37
HLHEENCO_01227 1.9e-34 T Toxin-antitoxin system, toxin component, MazF family
HLHEENCO_01228 7.4e-230 L transposase, IS605 OrfB family
HLHEENCO_01229 2.1e-60 L PFAM transposase IS200-family protein
HLHEENCO_01241 4.7e-111 S Membrane
HLHEENCO_01242 1.2e-64 O Zinc-dependent metalloprotease
HLHEENCO_01243 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLHEENCO_01244 1.2e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HLHEENCO_01246 1.5e-17 NU Mycoplasma protein of unknown function, DUF285
HLHEENCO_01247 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLHEENCO_01248 1.6e-105 ypsA S Belongs to the UPF0398 family
HLHEENCO_01249 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLHEENCO_01250 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HLHEENCO_01251 2e-161 EG EamA-like transporter family
HLHEENCO_01252 3e-125 dnaD L DnaD domain protein
HLHEENCO_01253 2.9e-85 ypmB S Protein conserved in bacteria
HLHEENCO_01254 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HLHEENCO_01255 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HLHEENCO_01256 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HLHEENCO_01257 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HLHEENCO_01258 1.4e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLHEENCO_01259 3.8e-87 S Protein of unknown function (DUF1440)
HLHEENCO_01260 0.0 rafA 3.2.1.22 G alpha-galactosidase
HLHEENCO_01261 4.2e-189 galR K Periplasmic binding protein-like domain
HLHEENCO_01262 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HLHEENCO_01263 9.3e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HLHEENCO_01264 2.6e-124 lrgB M LrgB-like family
HLHEENCO_01265 1.9e-66 lrgA S LrgA family
HLHEENCO_01266 2.4e-130 lytT K response regulator receiver
HLHEENCO_01267 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HLHEENCO_01268 4e-148 f42a O Band 7 protein
HLHEENCO_01269 2.5e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HLHEENCO_01270 6.4e-156 yitU 3.1.3.104 S hydrolase
HLHEENCO_01271 9.2e-39 S Cytochrome B5
HLHEENCO_01272 8.3e-114 nreC K PFAM regulatory protein LuxR
HLHEENCO_01273 6.1e-160 hipB K Helix-turn-helix
HLHEENCO_01274 2.8e-57 yitW S Iron-sulfur cluster assembly protein
HLHEENCO_01275 1.6e-271 sufB O assembly protein SufB
HLHEENCO_01276 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
HLHEENCO_01277 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLHEENCO_01278 7.3e-239 sufD O FeS assembly protein SufD
HLHEENCO_01279 6.5e-145 sufC O FeS assembly ATPase SufC
HLHEENCO_01280 4.2e-32 feoA P FeoA domain
HLHEENCO_01281 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HLHEENCO_01282 5.5e-19
HLHEENCO_01283 4.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLHEENCO_01284 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLHEENCO_01285 3.5e-64 ydiI Q Thioesterase superfamily
HLHEENCO_01286 2.4e-109 yvrI K sigma factor activity
HLHEENCO_01287 5e-202 G Transporter, major facilitator family protein
HLHEENCO_01288 0.0 S Bacterial membrane protein YfhO
HLHEENCO_01289 4.7e-102 T Ion transport 2 domain protein
HLHEENCO_01290 5.7e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLHEENCO_01291 2.1e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HLHEENCO_01292 7.3e-96 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HLHEENCO_01293 5e-185 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLHEENCO_01294 9e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HLHEENCO_01295 7.4e-230 L transposase, IS605 OrfB family
HLHEENCO_01296 2.1e-60 L PFAM transposase IS200-family protein
HLHEENCO_01297 1.7e-183 S Phosphotransferase system, EIIC
HLHEENCO_01298 2.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLHEENCO_01299 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLHEENCO_01300 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HLHEENCO_01301 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLHEENCO_01302 2.4e-223 mdtG EGP Major facilitator Superfamily
HLHEENCO_01303 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
HLHEENCO_01304 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLHEENCO_01307 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HLHEENCO_01308 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLHEENCO_01309 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
HLHEENCO_01310 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HLHEENCO_01311 2.9e-82
HLHEENCO_01312 1.5e-288 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLHEENCO_01313 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HLHEENCO_01314 0.0 yjbQ P TrkA C-terminal domain protein
HLHEENCO_01315 4.9e-273 pipD E Dipeptidase
HLHEENCO_01316 4.4e-100 L Helix-turn-helix domain
HLHEENCO_01317 4.5e-160 L hmm pf00665
HLHEENCO_01318 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLHEENCO_01319 3e-34
HLHEENCO_01320 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
HLHEENCO_01321 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HLHEENCO_01322 7.5e-86 ygfC K transcriptional regulator (TetR family)
HLHEENCO_01323 2.1e-183 hrtB V ABC transporter permease
HLHEENCO_01324 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HLHEENCO_01325 0.0 yhcA V ABC transporter, ATP-binding protein
HLHEENCO_01326 4.6e-38
HLHEENCO_01327 5.6e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLHEENCO_01328 3.9e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLHEENCO_01329 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLHEENCO_01330 7.5e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLHEENCO_01331 2.2e-36 S Domain of unknown function DUF1829
HLHEENCO_01332 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLHEENCO_01333 0.0 2.7.7.6 M Peptidase family M23
HLHEENCO_01334 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
HLHEENCO_01335 2.4e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HLHEENCO_01336 3.3e-146 cps1D M Domain of unknown function (DUF4422)
HLHEENCO_01337 7.9e-127 recX 2.4.1.337 GT4 S Regulatory protein RecX
HLHEENCO_01338 4.9e-31
HLHEENCO_01339 6.6e-34 S Protein of unknown function (DUF2922)
HLHEENCO_01340 3.2e-153 yihY S Belongs to the UPF0761 family
HLHEENCO_01341 1.1e-281 yjeM E Amino Acid
HLHEENCO_01342 1e-254 E Arginine ornithine antiporter
HLHEENCO_01343 1.7e-220 arcT 2.6.1.1 E Aminotransferase
HLHEENCO_01344 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HLHEENCO_01345 6.1e-79 fld C Flavodoxin
HLHEENCO_01346 2.3e-67 gtcA S Teichoic acid glycosylation protein
HLHEENCO_01347 9.3e-56
HLHEENCO_01348 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLHEENCO_01350 2.6e-228 yfmL L DEAD DEAH box helicase
HLHEENCO_01351 4.5e-191 mocA S Oxidoreductase
HLHEENCO_01352 9.1e-62 S Domain of unknown function (DUF4828)
HLHEENCO_01353 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HLHEENCO_01354 3.8e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HLHEENCO_01355 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HLHEENCO_01356 9.3e-197 S Protein of unknown function (DUF3114)
HLHEENCO_01357 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HLHEENCO_01358 1.1e-119 ybhL S Belongs to the BI1 family
HLHEENCO_01359 3.1e-21
HLHEENCO_01360 1.4e-95 K Acetyltransferase (GNAT) family
HLHEENCO_01361 1e-75 K LytTr DNA-binding domain
HLHEENCO_01362 7.3e-69 S Protein of unknown function (DUF3021)
HLHEENCO_01363 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HLHEENCO_01364 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
HLHEENCO_01365 2.6e-74 ogt 2.1.1.63 L Methyltransferase
HLHEENCO_01366 4.8e-122 pnb C nitroreductase
HLHEENCO_01367 2.1e-91
HLHEENCO_01368 1.4e-90 S B3 4 domain
HLHEENCO_01369 4e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HLHEENCO_01370 1.5e-156 amtB P ammonium transporter
HLHEENCO_01371 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HLHEENCO_01373 1.3e-46
HLHEENCO_01374 3.2e-96 S PFAM Archaeal ATPase
HLHEENCO_01375 0.0 csd1 3.5.1.28 G domain, Protein
HLHEENCO_01376 0.0 G Peptidase_C39 like family
HLHEENCO_01377 2.1e-25
HLHEENCO_01378 0.0 ganB 3.2.1.89 G arabinogalactan
HLHEENCO_01379 2.8e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
HLHEENCO_01380 4.8e-215 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HLHEENCO_01381 2.2e-75 rgpB GT2 M Glycosyl transferase family 2
HLHEENCO_01382 2.1e-116 S Glycosyltransferase like family 2
HLHEENCO_01383 5.9e-97 M Glycosyltransferase like family 2
HLHEENCO_01384 1.4e-95 cps3F
HLHEENCO_01385 4.1e-41 M biosynthesis protein
HLHEENCO_01386 1.4e-83 M Domain of unknown function (DUF4422)
HLHEENCO_01387 2e-87 S Glycosyltransferase like family
HLHEENCO_01388 0.0 M domain protein
HLHEENCO_01389 5.9e-91
HLHEENCO_01391 1.9e-159 yjcE P Sodium proton antiporter
HLHEENCO_01392 1e-73 yjcE P Sodium proton antiporter
HLHEENCO_01394 5.2e-56
HLHEENCO_01396 4.5e-85
HLHEENCO_01397 0.0 copA 3.6.3.54 P P-type ATPase
HLHEENCO_01398 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HLHEENCO_01399 2.5e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HLHEENCO_01400 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HLHEENCO_01401 3.3e-161 EG EamA-like transporter family
HLHEENCO_01402 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HLHEENCO_01403 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLHEENCO_01404 8.1e-154 KT YcbB domain
HLHEENCO_01405 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
HLHEENCO_01406 2.9e-196 xylR GK ROK family
HLHEENCO_01407 1.3e-28
HLHEENCO_01408 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
HLHEENCO_01409 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
HLHEENCO_01410 2.6e-155 glcU U sugar transport
HLHEENCO_01411 6.8e-273 yclK 2.7.13.3 T Histidine kinase
HLHEENCO_01412 5.7e-132 K response regulator
HLHEENCO_01414 2.8e-79 lytE M Lysin motif
HLHEENCO_01415 2e-149 XK27_02985 S Cof-like hydrolase
HLHEENCO_01416 2.3e-81 K Transcriptional regulator
HLHEENCO_01417 0.0 oatA I Acyltransferase
HLHEENCO_01418 8.7e-53
HLHEENCO_01419 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLHEENCO_01420 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLHEENCO_01421 2e-126 ybbR S YbbR-like protein
HLHEENCO_01422 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLHEENCO_01423 4.8e-249 fucP G Major Facilitator Superfamily
HLHEENCO_01424 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLHEENCO_01425 2.9e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLHEENCO_01426 1.6e-168 murB 1.3.1.98 M Cell wall formation
HLHEENCO_01427 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
HLHEENCO_01428 4.4e-76 S PAS domain
HLHEENCO_01429 2.6e-86 K Acetyltransferase (GNAT) domain
HLHEENCO_01430 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HLHEENCO_01431 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HLHEENCO_01432 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLHEENCO_01433 6.3e-105 yxjI
HLHEENCO_01434 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLHEENCO_01435 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLHEENCO_01436 3.4e-146 est 3.1.1.1 S Serine aminopeptidase, S33
HLHEENCO_01437 1.8e-34 secG U Preprotein translocase
HLHEENCO_01438 2.6e-291 clcA P chloride
HLHEENCO_01439 7.1e-248 yifK E Amino acid permease
HLHEENCO_01440 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLHEENCO_01441 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLHEENCO_01442 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HLHEENCO_01443 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLHEENCO_01445 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLHEENCO_01446 8.8e-15
HLHEENCO_01448 4e-170 whiA K May be required for sporulation
HLHEENCO_01449 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HLHEENCO_01450 1.1e-161 rapZ S Displays ATPase and GTPase activities
HLHEENCO_01451 5.4e-245 steT E amino acid
HLHEENCO_01452 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLHEENCO_01453 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLHEENCO_01454 1.5e-13
HLHEENCO_01455 2.3e-116 yfbR S HD containing hydrolase-like enzyme
HLHEENCO_01456 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLHEENCO_01457 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HLHEENCO_01458 1.3e-157 aatB ET PFAM extracellular solute-binding protein, family 3
HLHEENCO_01459 2.5e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HLHEENCO_01460 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLHEENCO_01461 3.5e-163 lutA C Cysteine-rich domain
HLHEENCO_01462 7.5e-288 lutB C 4Fe-4S dicluster domain
HLHEENCO_01463 3.9e-136 yrjD S LUD domain
HLHEENCO_01464 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HLHEENCO_01465 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HLHEENCO_01466 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLHEENCO_01467 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLHEENCO_01468 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HLHEENCO_01469 3.1e-32 KT PspC domain protein
HLHEENCO_01470 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLHEENCO_01471 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLHEENCO_01472 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLHEENCO_01473 1.3e-114 comFC S Competence protein
HLHEENCO_01474 1.4e-256 comFA L Helicase C-terminal domain protein
HLHEENCO_01475 2.9e-111 yvyE 3.4.13.9 S YigZ family
HLHEENCO_01476 4e-235 EGP Major facilitator Superfamily
HLHEENCO_01477 7.4e-68 rmaI K Transcriptional regulator
HLHEENCO_01478 9.2e-40
HLHEENCO_01479 0.0 ydaO E amino acid
HLHEENCO_01480 7.3e-305 ybeC E amino acid
HLHEENCO_01481 1.1e-81 S YbaK proline--tRNA ligase associated domain protein
HLHEENCO_01482 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLHEENCO_01483 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLHEENCO_01485 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLHEENCO_01486 3.2e-125 S Putative adhesin
HLHEENCO_01487 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
HLHEENCO_01488 4e-56 K transcriptional regulator PadR family
HLHEENCO_01489 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLHEENCO_01491 1.2e-230 L Integrase core domain
HLHEENCO_01492 5.1e-139 L Bacterial dnaA protein
HLHEENCO_01493 5.7e-38
HLHEENCO_01494 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLHEENCO_01495 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLHEENCO_01496 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLHEENCO_01497 9.6e-247 M Glycosyl transferase family group 2
HLHEENCO_01499 1.3e-226 aadAT EK Aminotransferase, class I
HLHEENCO_01500 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLHEENCO_01501 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLHEENCO_01502 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HLHEENCO_01503 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLHEENCO_01504 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HLHEENCO_01505 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLHEENCO_01506 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLHEENCO_01507 1.9e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLHEENCO_01508 1.7e-207 yacL S domain protein
HLHEENCO_01509 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLHEENCO_01510 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HLHEENCO_01511 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HLHEENCO_01512 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLHEENCO_01513 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
HLHEENCO_01514 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HLHEENCO_01515 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLHEENCO_01516 2.4e-119 tcyB E ABC transporter
HLHEENCO_01517 1.2e-213 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HLHEENCO_01518 3.1e-169 I alpha/beta hydrolase fold
HLHEENCO_01519 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLHEENCO_01520 0.0 S Bacterial membrane protein, YfhO
HLHEENCO_01521 2.7e-182 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HLHEENCO_01522 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HLHEENCO_01524 1.7e-81 ydcK S Belongs to the SprT family
HLHEENCO_01525 0.0 yhgF K Tex-like protein N-terminal domain protein
HLHEENCO_01526 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLHEENCO_01527 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLHEENCO_01528 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HLHEENCO_01529 2.4e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HLHEENCO_01530 1.8e-298 aspT P Predicted Permease Membrane Region
HLHEENCO_01531 2.8e-252 EGP Major facilitator Superfamily
HLHEENCO_01532 5.5e-110
HLHEENCO_01535 1.4e-158 yjjH S Calcineurin-like phosphoesterase
HLHEENCO_01536 5e-263 dtpT U amino acid peptide transporter
HLHEENCO_01537 3.7e-19
HLHEENCO_01539 3.7e-91 yqiG C Oxidoreductase
HLHEENCO_01540 3.7e-84 yqiG C Oxidoreductase
HLHEENCO_01541 8.5e-54 S macrophage migration inhibitory factor
HLHEENCO_01542 2.4e-65 K HxlR-like helix-turn-helix
HLHEENCO_01543 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLHEENCO_01545 1.9e-225 L Transposase IS66 family
HLHEENCO_01546 5.9e-114 L PFAM Integrase catalytic region
HLHEENCO_01547 3.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLHEENCO_01548 1e-265 yfnA E amino acid
HLHEENCO_01549 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLHEENCO_01550 5.8e-40 1.3.5.4 S FMN binding
HLHEENCO_01551 3.7e-221 norA EGP Major facilitator Superfamily
HLHEENCO_01552 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HLHEENCO_01553 4.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HLHEENCO_01554 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLHEENCO_01555 3.1e-103 metI P ABC transporter permease
HLHEENCO_01556 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HLHEENCO_01557 1.3e-251 clcA P chloride
HLHEENCO_01558 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HLHEENCO_01559 4.5e-104 proW P ABC transporter, permease protein
HLHEENCO_01560 1e-139 proV E ABC transporter, ATP-binding protein
HLHEENCO_01561 6.3e-109 proWZ P ABC transporter permease
HLHEENCO_01562 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
HLHEENCO_01563 9e-75 K Transcriptional regulator
HLHEENCO_01564 4.8e-154 1.6.5.2 GM NAD(P)H-binding
HLHEENCO_01566 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
HLHEENCO_01567 0.0 cadA P P-type ATPase
HLHEENCO_01568 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HLHEENCO_01569 2.1e-126
HLHEENCO_01570 3.3e-55 S Sugar efflux transporter for intercellular exchange
HLHEENCO_01571 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HLHEENCO_01573 0.0 L Helicase C-terminal domain protein
HLHEENCO_01574 6.9e-76 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HLHEENCO_01575 2.2e-176 S Aldo keto reductase
HLHEENCO_01577 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLHEENCO_01578 4.5e-62 psiE S Phosphate-starvation-inducible E
HLHEENCO_01579 2.1e-102 ydeN S Serine hydrolase
HLHEENCO_01581 3.4e-155 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLHEENCO_01582 6.1e-255 nhaC C Na H antiporter NhaC
HLHEENCO_01583 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
HLHEENCO_01584 4.8e-114 ywnB S NAD(P)H-binding
HLHEENCO_01585 9.2e-36
HLHEENCO_01586 9.3e-130 IQ Dehydrogenase reductase
HLHEENCO_01587 1.5e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HLHEENCO_01589 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLHEENCO_01590 9.7e-173
HLHEENCO_01591 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLHEENCO_01592 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
HLHEENCO_01593 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HLHEENCO_01594 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLHEENCO_01595 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HLHEENCO_01596 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLHEENCO_01597 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLHEENCO_01598 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLHEENCO_01599 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLHEENCO_01600 9.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HLHEENCO_01601 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLHEENCO_01602 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLHEENCO_01603 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLHEENCO_01604 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HLHEENCO_01605 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HLHEENCO_01606 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HLHEENCO_01607 4.9e-177 K AI-2E family transporter
HLHEENCO_01608 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HLHEENCO_01609 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HLHEENCO_01610 5.1e-116 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HLHEENCO_01611 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLHEENCO_01612 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLHEENCO_01613 3.3e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLHEENCO_01614 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLHEENCO_01615 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HLHEENCO_01616 7.4e-134 K LysR substrate binding domain
HLHEENCO_01617 1.6e-38 L PFAM transposase IS200-family protein
HLHEENCO_01618 4.3e-83 usp6 T universal stress protein
HLHEENCO_01619 1.7e-45
HLHEENCO_01620 1.7e-235 rarA L recombination factor protein RarA
HLHEENCO_01621 7.1e-86 yueI S Protein of unknown function (DUF1694)
HLHEENCO_01622 1.5e-21
HLHEENCO_01623 8.1e-75 4.4.1.5 E Glyoxalase
HLHEENCO_01624 2.5e-138 S Membrane
HLHEENCO_01625 2.5e-135 S Belongs to the UPF0246 family
HLHEENCO_01626 1.1e-206 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HLHEENCO_01627 8.2e-93 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HLHEENCO_01628 4.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HLHEENCO_01629 1.1e-235 pbuG S permease
HLHEENCO_01630 1.3e-262 L Transposase
HLHEENCO_01631 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLHEENCO_01632 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLHEENCO_01633 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HLHEENCO_01634 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLHEENCO_01635 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLHEENCO_01636 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
HLHEENCO_01637 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HLHEENCO_01638 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLHEENCO_01639 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLHEENCO_01640 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
HLHEENCO_01641 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HLHEENCO_01642 6.8e-121 radC L DNA repair protein
HLHEENCO_01643 1.7e-179 mreB D cell shape determining protein MreB
HLHEENCO_01644 8.5e-151 mreC M Involved in formation and maintenance of cell shape
HLHEENCO_01645 1.2e-91 mreD M rod shape-determining protein MreD
HLHEENCO_01646 3.2e-102 glnP P ABC transporter permease
HLHEENCO_01647 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLHEENCO_01648 2.6e-160 aatB ET ABC transporter substrate-binding protein
HLHEENCO_01649 1.6e-230 ymfF S Peptidase M16 inactive domain protein
HLHEENCO_01650 6e-249 ymfH S Peptidase M16
HLHEENCO_01651 7.4e-141 ymfM S Helix-turn-helix domain
HLHEENCO_01652 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLHEENCO_01653 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
HLHEENCO_01654 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLHEENCO_01655 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HLHEENCO_01656 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HLHEENCO_01657 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
HLHEENCO_01658 2e-92 folT S ECF transporter, substrate-specific component
HLHEENCO_01659 0.0 pepN 3.4.11.2 E aminopeptidase
HLHEENCO_01660 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
HLHEENCO_01661 9.8e-255 pepC 3.4.22.40 E aminopeptidase
HLHEENCO_01662 6.5e-210 EGP Major facilitator Superfamily
HLHEENCO_01663 2.4e-229
HLHEENCO_01664 7.8e-79 K Transcriptional regulator, HxlR family
HLHEENCO_01665 3.7e-108 XK27_02070 S Nitroreductase family
HLHEENCO_01666 2.5e-52 hxlR K Transcriptional regulator, HxlR family
HLHEENCO_01667 3e-119 GM NmrA-like family
HLHEENCO_01668 1.7e-70 elaA S Gnat family
HLHEENCO_01669 1.8e-39 S Cytochrome B5
HLHEENCO_01670 5.4e-09 S Cytochrome B5
HLHEENCO_01671 7.8e-41 S Cytochrome B5
HLHEENCO_01672 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
HLHEENCO_01674 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLHEENCO_01675 1.1e-240 E amino acid
HLHEENCO_01676 2.8e-215 npp S type I phosphodiesterase nucleotide pyrophosphatase
HLHEENCO_01677 3.1e-226 yxiO S Vacuole effluxer Atg22 like
HLHEENCO_01679 4.4e-100 L Helix-turn-helix domain
HLHEENCO_01680 4.5e-160 L hmm pf00665
HLHEENCO_01681 5.5e-110 dedA S SNARE-like domain protein
HLHEENCO_01682 7e-105 S Protein of unknown function (DUF1461)
HLHEENCO_01683 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLHEENCO_01684 1.3e-93 yutD S Protein of unknown function (DUF1027)
HLHEENCO_01685 2.2e-113 S Calcineurin-like phosphoesterase
HLHEENCO_01686 2.3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLHEENCO_01687 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
HLHEENCO_01689 6.3e-70
HLHEENCO_01690 2.7e-40
HLHEENCO_01691 8.3e-78 NU general secretion pathway protein
HLHEENCO_01692 7.1e-47 comGC U competence protein ComGC
HLHEENCO_01693 9.5e-181 comGB NU type II secretion system
HLHEENCO_01694 2.6e-180 comGA NU Type II IV secretion system protein
HLHEENCO_01695 3.5e-132 yebC K Transcriptional regulatory protein
HLHEENCO_01696 1.9e-134
HLHEENCO_01697 1.9e-181 ccpA K catabolite control protein A
HLHEENCO_01698 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HLHEENCO_01699 3.5e-26
HLHEENCO_01700 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLHEENCO_01701 3.4e-147 ykuT M mechanosensitive ion channel
HLHEENCO_01702 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HLHEENCO_01703 3.6e-76 ykuL S (CBS) domain
HLHEENCO_01704 4.4e-94 S Phosphoesterase
HLHEENCO_01705 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLHEENCO_01706 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HLHEENCO_01707 1.3e-96 yslB S Protein of unknown function (DUF2507)
HLHEENCO_01708 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
HLHEENCO_01709 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLHEENCO_01710 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
HLHEENCO_01711 6.7e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HLHEENCO_01712 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLHEENCO_01713 2.7e-39 ptsH G phosphocarrier protein HPR
HLHEENCO_01714 2.9e-27
HLHEENCO_01715 0.0 clpE O Belongs to the ClpA ClpB family
HLHEENCO_01716 2.4e-99 S Pfam:DUF3816
HLHEENCO_01717 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HLHEENCO_01718 6.7e-114
HLHEENCO_01719 1e-156 V ABC transporter, ATP-binding protein
HLHEENCO_01720 7.9e-64 gntR1 K Transcriptional regulator, GntR family
HLHEENCO_01721 0.0 bamA GM domain, Protein
HLHEENCO_01722 0.0 S Peptidase, M23
HLHEENCO_01723 7e-55 M NlpC/P60 family
HLHEENCO_01724 1.2e-174 M NlpC/P60 family
HLHEENCO_01725 4.7e-217 M NlpC/P60 family
HLHEENCO_01726 6.4e-34 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HLHEENCO_01727 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLHEENCO_01728 6.9e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HLHEENCO_01729 1.1e-163 yueF S AI-2E family transporter
HLHEENCO_01730 4.1e-37 S Uncharacterised protein family (UPF0236)
HLHEENCO_01732 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLHEENCO_01733 0.0 helD 3.6.4.12 L DNA helicase
HLHEENCO_01734 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
HLHEENCO_01735 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HLHEENCO_01736 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLHEENCO_01737 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HLHEENCO_01738 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HLHEENCO_01739 1.6e-177
HLHEENCO_01740 1e-130 cobB K SIR2 family
HLHEENCO_01742 3.6e-162 yunF F Protein of unknown function DUF72
HLHEENCO_01743 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLHEENCO_01744 1.9e-155 tatD L hydrolase, TatD family
HLHEENCO_01745 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLHEENCO_01746 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLHEENCO_01747 6.8e-37 veg S Biofilm formation stimulator VEG
HLHEENCO_01748 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLHEENCO_01749 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
HLHEENCO_01750 2.2e-122 fhuC P ABC transporter
HLHEENCO_01751 1.4e-118 znuB U ABC 3 transport family
HLHEENCO_01752 2.6e-149 purR 2.4.2.7 F pur operon repressor
HLHEENCO_01753 3.4e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLHEENCO_01754 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLHEENCO_01755 2.1e-49
HLHEENCO_01756 2.5e-147 yxeH S hydrolase
HLHEENCO_01757 5e-270 ywfO S HD domain protein
HLHEENCO_01758 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HLHEENCO_01759 3e-66 ywiB S Domain of unknown function (DUF1934)
HLHEENCO_01760 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLHEENCO_01761 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLHEENCO_01762 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLHEENCO_01763 4.6e-41 rpmE2 J Ribosomal protein L31
HLHEENCO_01764 1.8e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLHEENCO_01765 1.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HLHEENCO_01766 5.1e-125 srtA 3.4.22.70 M sortase family
HLHEENCO_01767 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HLHEENCO_01768 4.4e-157 3.2.1.55 GH51 G Right handed beta helix region
HLHEENCO_01769 4e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLHEENCO_01770 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HLHEENCO_01771 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HLHEENCO_01772 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLHEENCO_01773 7e-93 lemA S LemA family
HLHEENCO_01774 2.6e-158 htpX O Belongs to the peptidase M48B family
HLHEENCO_01775 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLHEENCO_01776 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLHEENCO_01777 1.1e-126 L PFAM Integrase catalytic region
HLHEENCO_01778 5e-141 sprD D Domain of Unknown Function (DUF1542)
HLHEENCO_01779 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
HLHEENCO_01780 2.3e-78 O Bacterial dnaA protein
HLHEENCO_01781 9.8e-09 K DNA-binding helix-turn-helix protein
HLHEENCO_01782 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HLHEENCO_01783 3.7e-54
HLHEENCO_01784 9.9e-206 yttB EGP Major facilitator Superfamily
HLHEENCO_01785 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HLHEENCO_01786 2e-74 rplI J Binds to the 23S rRNA
HLHEENCO_01787 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HLHEENCO_01788 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLHEENCO_01789 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLHEENCO_01790 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HLHEENCO_01791 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLHEENCO_01792 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLHEENCO_01793 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLHEENCO_01794 1.7e-34 yaaA S S4 domain protein YaaA
HLHEENCO_01795 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HLHEENCO_01796 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HLHEENCO_01797 9.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLHEENCO_01798 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLHEENCO_01799 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HLHEENCO_01800 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLHEENCO_01801 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLHEENCO_01802 9.7e-130 jag S R3H domain protein
HLHEENCO_01803 8.7e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLHEENCO_01804 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLHEENCO_01805 0.0 asnB 6.3.5.4 E Asparagine synthase
HLHEENCO_01806 1.5e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLHEENCO_01807 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HLHEENCO_01808 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HLHEENCO_01809 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
HLHEENCO_01810 1.8e-161 S reductase
HLHEENCO_01812 3.6e-288 S amidohydrolase
HLHEENCO_01813 5.9e-152 K Aminotransferase class I and II
HLHEENCO_01814 7.3e-60 K Aminotransferase class I and II
HLHEENCO_01815 1.4e-119 azlC E azaleucine resistance protein AzlC
HLHEENCO_01816 7.1e-50 azlD E Branched-chain amino acid transport
HLHEENCO_01817 6.1e-117 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HLHEENCO_01819 2.7e-70 S GyrI-like small molecule binding domain
HLHEENCO_01820 6.4e-39 S GyrI-like small molecule binding domain
HLHEENCO_01821 5e-122 yhiD S MgtC family
HLHEENCO_01822 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HLHEENCO_01823 5.9e-191 V Beta-lactamase
HLHEENCO_01825 4.4e-100 L Helix-turn-helix domain
HLHEENCO_01826 4.5e-160 L hmm pf00665
HLHEENCO_01827 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HLHEENCO_01828 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLHEENCO_01829 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HLHEENCO_01830 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLHEENCO_01831 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLHEENCO_01832 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLHEENCO_01833 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLHEENCO_01834 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLHEENCO_01835 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLHEENCO_01836 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HLHEENCO_01837 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLHEENCO_01838 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLHEENCO_01839 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLHEENCO_01840 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLHEENCO_01841 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLHEENCO_01842 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLHEENCO_01843 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLHEENCO_01844 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLHEENCO_01845 2.9e-24 rpmD J Ribosomal protein L30
HLHEENCO_01846 8.9e-64 rplO J Binds to the 23S rRNA
HLHEENCO_01847 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLHEENCO_01848 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLHEENCO_01849 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLHEENCO_01850 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HLHEENCO_01851 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLHEENCO_01852 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLHEENCO_01853 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHEENCO_01854 1.1e-62 rplQ J Ribosomal protein L17
HLHEENCO_01855 8.8e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHEENCO_01856 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHEENCO_01857 2.2e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHEENCO_01858 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLHEENCO_01859 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLHEENCO_01860 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HLHEENCO_01861 3.8e-70 yqeY S YqeY-like protein
HLHEENCO_01862 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HLHEENCO_01863 5.9e-264 glnPH2 P ABC transporter permease
HLHEENCO_01864 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLHEENCO_01865 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLHEENCO_01866 1e-164 yniA G Phosphotransferase enzyme family
HLHEENCO_01867 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLHEENCO_01868 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLHEENCO_01869 1.1e-50
HLHEENCO_01870 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLHEENCO_01871 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
HLHEENCO_01872 2.8e-57
HLHEENCO_01874 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HLHEENCO_01876 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HLHEENCO_01877 4.1e-275 pipD E Dipeptidase
HLHEENCO_01878 1.5e-89 K IrrE N-terminal-like domain
HLHEENCO_01879 2e-30
HLHEENCO_01880 3.2e-198 3.5.1.104 M hydrolase, family 25
HLHEENCO_01881 9.8e-63 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HLHEENCO_01882 5.3e-15
HLHEENCO_01888 0.0 cotH M CotH kinase protein
HLHEENCO_01890 9.5e-259 3.4.24.40 M Peptidase family M23
HLHEENCO_01891 4.1e-158 S Phage tail protein
HLHEENCO_01892 0.0 M Phage tail tape measure protein TP901
HLHEENCO_01893 4.6e-24
HLHEENCO_01894 4.6e-58
HLHEENCO_01895 2.2e-116
HLHEENCO_01896 4.9e-75
HLHEENCO_01897 7.2e-62 S Bacteriophage HK97-gp10, putative tail-component
HLHEENCO_01898 2.5e-39 S Phage head-tail joining protein
HLHEENCO_01899 1.1e-63 S Phage gp6-like head-tail connector protein
HLHEENCO_01900 5.9e-208 S Phage capsid family
HLHEENCO_01901 2.4e-113 pi136 S Caudovirus prohead serine protease
HLHEENCO_01902 2.6e-212 S Phage portal protein
HLHEENCO_01904 0.0 terL S overlaps another CDS with the same product name
HLHEENCO_01905 1.3e-76 terS L Phage terminase, small subunit
HLHEENCO_01906 2.8e-154 L HNH nucleases
HLHEENCO_01907 1.2e-08
HLHEENCO_01909 1.9e-83 arpU S Phage transcriptional regulator, ArpU family
HLHEENCO_01914 3.6e-129
HLHEENCO_01915 1.3e-67
HLHEENCO_01917 4.4e-123 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HLHEENCO_01918 2.2e-190 L Belongs to the 'phage' integrase family
HLHEENCO_01919 5.3e-119 L DnaD domain protein
HLHEENCO_01922 8e-15
HLHEENCO_01926 2.8e-10 K Helix-turn-helix XRE-family like proteins
HLHEENCO_01927 1.8e-79 3.4.21.88 K Peptidase S24-like
HLHEENCO_01929 7e-16
HLHEENCO_01932 6.5e-47
HLHEENCO_01934 5.1e-223 3.6.4.12 L Belongs to the 'phage' integrase family
HLHEENCO_01935 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLHEENCO_01936 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLHEENCO_01937 0.0 dnaK O Heat shock 70 kDa protein
HLHEENCO_01938 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLHEENCO_01939 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLHEENCO_01940 5.8e-64
HLHEENCO_01941 4.8e-39 L Integrase core domain
HLHEENCO_01942 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HLHEENCO_01943 6.7e-93 dps P Belongs to the Dps family
HLHEENCO_01944 7.9e-35 copZ C Heavy-metal-associated domain
HLHEENCO_01945 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HLHEENCO_01946 8.2e-274 arcD S C4-dicarboxylate anaerobic carrier
HLHEENCO_01947 2.6e-255 ytjP 3.5.1.18 E Dipeptidase
HLHEENCO_01948 5.3e-215 uhpT EGP Major facilitator Superfamily
HLHEENCO_01949 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HLHEENCO_01950 4.8e-132 ponA V Beta-lactamase enzyme family
HLHEENCO_01955 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HLHEENCO_01958 6.1e-140 IQ reductase
HLHEENCO_01959 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
HLHEENCO_01960 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLHEENCO_01961 5.7e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLHEENCO_01962 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HLHEENCO_01963 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLHEENCO_01964 2.1e-202 camS S sex pheromone
HLHEENCO_01965 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLHEENCO_01966 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLHEENCO_01967 5.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLHEENCO_01968 5.1e-187 yegS 2.7.1.107 G Lipid kinase
HLHEENCO_01969 1e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLHEENCO_01970 9.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HLHEENCO_01971 0.0 L Helicase C-terminal domain protein
HLHEENCO_01972 1.4e-20
HLHEENCO_01973 3.9e-27 mleP3 S Membrane transport protein
HLHEENCO_01974 7.3e-121 T Transcriptional regulatory protein, C terminal
HLHEENCO_01975 9.9e-239 T GHKL domain
HLHEENCO_01976 4.7e-109 S Peptidase propeptide and YPEB domain
HLHEENCO_01977 1.7e-76 P FAD-binding domain
HLHEENCO_01978 4.3e-55 yphJ 4.1.1.44 S decarboxylase
HLHEENCO_01979 5.3e-83 K Bacterial regulatory proteins, tetR family
HLHEENCO_01980 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HLHEENCO_01981 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HLHEENCO_01982 9.9e-143 S Oxidoreductase, aldo keto reductase family protein
HLHEENCO_01983 2.6e-12 S Oxidoreductase, aldo keto reductase family protein
HLHEENCO_01984 2.7e-85 C Flavodoxin
HLHEENCO_01985 1.2e-123 K Transcriptional regulator
HLHEENCO_01986 1.7e-28 K Transcriptional regulator
HLHEENCO_01987 6.3e-88 lacA S transferase hexapeptide repeat
HLHEENCO_01988 9.4e-32 S thiolester hydrolase activity
HLHEENCO_01989 2e-152 S Alpha beta hydrolase
HLHEENCO_01990 2.3e-93 padC Q Phenolic acid decarboxylase
HLHEENCO_01991 9.5e-92 padR K Virulence activator alpha C-term
HLHEENCO_01992 5.2e-65 GM NAD(P)H-binding
HLHEENCO_01993 2.3e-155 ypuA S Protein of unknown function (DUF1002)
HLHEENCO_01994 1.5e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
HLHEENCO_01995 2.3e-57 K Transcriptional regulator
HLHEENCO_01996 4.3e-40 K Transcriptional regulator
HLHEENCO_01997 2.9e-162 akr5f 1.1.1.346 S reductase
HLHEENCO_01998 1.4e-102 K Transcriptional regulator C-terminal region
HLHEENCO_01999 2.1e-74 S membrane
HLHEENCO_02000 6.1e-88 S membrane
HLHEENCO_02001 1.2e-112 GM NAD(P)H-binding
HLHEENCO_02002 1.1e-64 yneR
HLHEENCO_02003 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
HLHEENCO_02004 1.3e-66 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLHEENCO_02005 4.3e-25 UW LPXTG-motif cell wall anchor domain protein
HLHEENCO_02014 3.9e-133 K Transcriptional regulatory protein, C-terminal domain protein
HLHEENCO_02015 7.3e-158 pstS P Phosphate
HLHEENCO_02016 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
HLHEENCO_02017 5.5e-153 pstA P Phosphate transport system permease protein PstA
HLHEENCO_02018 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLHEENCO_02019 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
HLHEENCO_02020 5e-75 osmC O OsmC-like protein
HLHEENCO_02021 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHEENCO_02022 1.8e-215 patA 2.6.1.1 E Aminotransferase
HLHEENCO_02023 7.8e-32
HLHEENCO_02024 0.0 clpL O associated with various cellular activities
HLHEENCO_02026 9.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
HLHEENCO_02027 6.1e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHEENCO_02028 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLHEENCO_02029 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HLHEENCO_02030 1.5e-172 malR K Transcriptional regulator, LacI family
HLHEENCO_02031 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
HLHEENCO_02032 1.1e-256 malT G Major Facilitator
HLHEENCO_02033 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HLHEENCO_02034 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HLHEENCO_02035 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
HLHEENCO_02036 3.3e-118 K response regulator
HLHEENCO_02037 5.3e-226 sptS 2.7.13.3 T Histidine kinase
HLHEENCO_02038 2.5e-209 yfeO P Voltage gated chloride channel
HLHEENCO_02039 8.9e-256 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HLHEENCO_02040 6.6e-136 puuD S peptidase C26
HLHEENCO_02041 3.8e-167 yvgN C Aldo keto reductase
HLHEENCO_02042 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
HLHEENCO_02043 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HLHEENCO_02044 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
HLHEENCO_02045 4.2e-261 nox C NADH oxidase
HLHEENCO_02046 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLHEENCO_02047 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLHEENCO_02048 3e-86
HLHEENCO_02049 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLHEENCO_02051 3e-75
HLHEENCO_02056 7.4e-40 L Integrase core domain
HLHEENCO_02057 4.8e-81 prrC S Protein conserved in bacteria
HLHEENCO_02058 6.3e-25
HLHEENCO_02059 3.7e-39 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLHEENCO_02060 1.4e-96
HLHEENCO_02061 2.2e-20 QT PucR C-terminal helix-turn-helix domain
HLHEENCO_02063 6.3e-131 1.6.5.2 GM NAD(P)H-binding
HLHEENCO_02065 5.5e-29 S Protein of unknown function (DUF4065)
HLHEENCO_02066 1.5e-64 doc
HLHEENCO_02067 6.6e-262 S Putative peptidoglycan binding domain
HLHEENCO_02068 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HLHEENCO_02069 2.2e-87
HLHEENCO_02070 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HLHEENCO_02071 2.6e-214 yttB EGP Major facilitator Superfamily
HLHEENCO_02072 8.2e-103
HLHEENCO_02073 3e-24
HLHEENCO_02074 5.1e-173 scrR K Transcriptional regulator, LacI family
HLHEENCO_02075 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLHEENCO_02076 3.5e-49 czrA K Transcriptional regulator, ArsR family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)