ORF_ID e_value Gene_name EC_number CAZy COGs Description
PCDPMHHH_00002 0.0 M LPXTG-motif cell wall anchor domain protein
PCDPMHHH_00003 0.0 trxB2 1.8.1.9 C Thioredoxin domain
PCDPMHHH_00004 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
PCDPMHHH_00005 3e-143 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PCDPMHHH_00006 6.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PCDPMHHH_00008 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PCDPMHHH_00009 5.5e-166 T Calcineurin-like phosphoesterase superfamily domain
PCDPMHHH_00010 8.2e-224 mdtG EGP Major facilitator Superfamily
PCDPMHHH_00011 1.7e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PCDPMHHH_00012 4.2e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
PCDPMHHH_00013 3.9e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
PCDPMHHH_00014 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PCDPMHHH_00015 3.2e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PCDPMHHH_00016 7.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PCDPMHHH_00017 4.7e-172 K AI-2E family transporter
PCDPMHHH_00018 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PCDPMHHH_00019 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PCDPMHHH_00020 4.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PCDPMHHH_00021 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PCDPMHHH_00022 1.4e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PCDPMHHH_00023 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PCDPMHHH_00024 4.5e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PCDPMHHH_00025 2.6e-36 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCDPMHHH_00026 1.3e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCDPMHHH_00027 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCDPMHHH_00028 2.5e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PCDPMHHH_00029 2.2e-193 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PCDPMHHH_00030 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PCDPMHHH_00031 1.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PCDPMHHH_00032 2.8e-243 purD 6.3.4.13 F Belongs to the GARS family
PCDPMHHH_00033 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PCDPMHHH_00034 5.5e-152
PCDPMHHH_00035 8.4e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PCDPMHHH_00046 1.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
PCDPMHHH_00047 2.1e-293 L Transposase IS66 family
PCDPMHHH_00048 4.6e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
PCDPMHHH_00049 3.7e-236 lmrB EGP Major facilitator Superfamily
PCDPMHHH_00050 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PCDPMHHH_00051 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCDPMHHH_00052 1.4e-159 sufD O Uncharacterized protein family (UPF0051)
PCDPMHHH_00053 1.6e-42 lytE M LysM domain protein
PCDPMHHH_00054 0.0 oppD EP Psort location Cytoplasmic, score
PCDPMHHH_00055 4.2e-87 lytE M LysM domain protein
PCDPMHHH_00056 2.4e-149 xth 3.1.11.2 L exodeoxyribonuclease III
PCDPMHHH_00057 1.4e-234 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PCDPMHHH_00058 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
PCDPMHHH_00059 5.8e-152 yeaE S Aldo keto
PCDPMHHH_00060 1e-75 hsp O Belongs to the small heat shock protein (HSP20) family
PCDPMHHH_00061 1.8e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PCDPMHHH_00062 1.5e-79 S Psort location Cytoplasmic, score
PCDPMHHH_00063 7.7e-86 S Short repeat of unknown function (DUF308)
PCDPMHHH_00064 1e-23
PCDPMHHH_00065 1.4e-101 V VanZ like family
PCDPMHHH_00066 1e-230 cycA E Amino acid permease
PCDPMHHH_00067 4.3e-85 perR P Belongs to the Fur family
PCDPMHHH_00068 3.2e-259 EGP Major facilitator Superfamily
PCDPMHHH_00069 3.9e-93 tag 3.2.2.20 L glycosylase
PCDPMHHH_00070 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PCDPMHHH_00071 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PCDPMHHH_00072 1.9e-40
PCDPMHHH_00073 4.1e-303 ytgP S Polysaccharide biosynthesis protein
PCDPMHHH_00074 5.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PCDPMHHH_00075 6.2e-276 pepV 3.5.1.18 E dipeptidase PepV
PCDPMHHH_00076 1.9e-86 uspA T Belongs to the universal stress protein A family
PCDPMHHH_00077 3.3e-181 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PCDPMHHH_00078 1.5e-115 dck 2.7.1.74 F deoxynucleoside kinase
PCDPMHHH_00079 5.9e-114
PCDPMHHH_00080 3.7e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
PCDPMHHH_00081 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCDPMHHH_00082 2.1e-32
PCDPMHHH_00083 5.2e-119 S CAAX protease self-immunity
PCDPMHHH_00084 1.9e-43
PCDPMHHH_00086 2.6e-70
PCDPMHHH_00087 7.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PCDPMHHH_00088 2e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PCDPMHHH_00089 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PCDPMHHH_00090 1.8e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PCDPMHHH_00091 5e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PCDPMHHH_00092 2.8e-213 folP 2.5.1.15 H dihydropteroate synthase
PCDPMHHH_00093 1e-43
PCDPMHHH_00094 3.3e-40
PCDPMHHH_00096 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PCDPMHHH_00097 2.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PCDPMHHH_00098 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PCDPMHHH_00099 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PCDPMHHH_00100 9.4e-38 yheA S Belongs to the UPF0342 family
PCDPMHHH_00101 7.7e-219 yhaO L Ser Thr phosphatase family protein
PCDPMHHH_00102 0.0 L AAA domain
PCDPMHHH_00103 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PCDPMHHH_00105 8.3e-78 hit FG histidine triad
PCDPMHHH_00106 1e-136 ecsA V ABC transporter, ATP-binding protein
PCDPMHHH_00107 6e-219 ecsB U ABC transporter
PCDPMHHH_00108 2.8e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PCDPMHHH_00109 0.0 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
PCDPMHHH_00110 1.6e-261 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PCDPMHHH_00111 1.3e-184 iolS C Aldo keto reductase
PCDPMHHH_00112 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
PCDPMHHH_00113 7.5e-58 ytzB S Small secreted protein
PCDPMHHH_00114 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PCDPMHHH_00115 7.2e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PCDPMHHH_00116 3.8e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PCDPMHHH_00117 1.6e-118 ybhL S Belongs to the BI1 family
PCDPMHHH_00118 1.8e-119 yoaK S Protein of unknown function (DUF1275)
PCDPMHHH_00119 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCDPMHHH_00120 5.7e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PCDPMHHH_00121 3.9e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PCDPMHHH_00122 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PCDPMHHH_00123 8.6e-206 dnaB L replication initiation and membrane attachment
PCDPMHHH_00124 4.8e-171 dnaI L Primosomal protein DnaI
PCDPMHHH_00125 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PCDPMHHH_00126 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PCDPMHHH_00127 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PCDPMHHH_00128 3.7e-96 yqeG S HAD phosphatase, family IIIA
PCDPMHHH_00129 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
PCDPMHHH_00130 1.9e-47 yhbY J RNA-binding protein
PCDPMHHH_00131 4.3e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PCDPMHHH_00132 4.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PCDPMHHH_00133 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PCDPMHHH_00134 1.1e-138 yqeM Q Methyltransferase
PCDPMHHH_00135 2e-208 ylbM S Belongs to the UPF0348 family
PCDPMHHH_00136 2.9e-99 yceD S Uncharacterized ACR, COG1399
PCDPMHHH_00137 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PCDPMHHH_00138 5.6e-121 K response regulator
PCDPMHHH_00139 5.4e-278 arlS 2.7.13.3 T Histidine kinase
PCDPMHHH_00140 1.8e-268 yjeM E Amino Acid
PCDPMHHH_00141 1.2e-231 V MatE
PCDPMHHH_00142 8.2e-67 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PCDPMHHH_00143 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PCDPMHHH_00144 1.7e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PCDPMHHH_00145 1.4e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
PCDPMHHH_00146 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PCDPMHHH_00147 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PCDPMHHH_00148 5.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PCDPMHHH_00149 9.6e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PCDPMHHH_00150 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PCDPMHHH_00151 3.5e-136 K LysR substrate binding domain
PCDPMHHH_00152 3.6e-52 azlD S branched-chain amino acid
PCDPMHHH_00153 2.7e-139 azlC E AzlC protein
PCDPMHHH_00154 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
PCDPMHHH_00155 3.8e-125 K response regulator
PCDPMHHH_00156 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PCDPMHHH_00157 1.3e-171 deoR K sugar-binding domain protein
PCDPMHHH_00158 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PCDPMHHH_00159 1e-235 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
PCDPMHHH_00160 7e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PCDPMHHH_00161 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PCDPMHHH_00162 7e-136 XK27_01040 S Protein of unknown function (DUF1129)
PCDPMHHH_00163 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PCDPMHHH_00164 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
PCDPMHHH_00165 5.5e-153 spo0J K Belongs to the ParB family
PCDPMHHH_00166 3.9e-139 soj D Sporulation initiation inhibitor
PCDPMHHH_00167 4.2e-146 noc K Belongs to the ParB family
PCDPMHHH_00168 3.8e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PCDPMHHH_00169 3.8e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PCDPMHHH_00170 2.7e-171 rihC 3.2.2.1 F Nucleoside
PCDPMHHH_00171 1e-218 nupG F Nucleoside transporter
PCDPMHHH_00172 1.3e-222 cycA E Amino acid permease
PCDPMHHH_00173 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCDPMHHH_00174 3e-265 glnP P ABC transporter
PCDPMHHH_00175 4.2e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PCDPMHHH_00176 0.0 infB UW LPXTG-motif cell wall anchor domain protein
PCDPMHHH_00177 0.0 fhaB M Rib/alpha-like repeat
PCDPMHHH_00178 0.0 fhaB M Rib/alpha-like repeat
PCDPMHHH_00179 5.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PCDPMHHH_00180 2e-196 XK27_09615 S reductase
PCDPMHHH_00181 4.9e-102 nqr 1.5.1.36 S reductase
PCDPMHHH_00182 4.8e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCDPMHHH_00183 3.5e-180 K Transcriptional regulator, LacI family
PCDPMHHH_00184 4.7e-260 G Major Facilitator
PCDPMHHH_00185 1.1e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PCDPMHHH_00186 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PCDPMHHH_00187 1.5e-266 G Major Facilitator
PCDPMHHH_00188 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
PCDPMHHH_00189 7e-296 M domain protein
PCDPMHHH_00190 1.5e-267 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PCDPMHHH_00191 1.9e-270 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
PCDPMHHH_00192 4.6e-70
PCDPMHHH_00193 3e-155 ypuA S Protein of unknown function (DUF1002)
PCDPMHHH_00194 1.1e-65 GM NAD(P)H-binding
PCDPMHHH_00195 6.5e-93 padR K Virulence activator alpha C-term
PCDPMHHH_00196 2.7e-94 padC Q Phenolic acid decarboxylase
PCDPMHHH_00197 2.9e-151 S Alpha beta hydrolase
PCDPMHHH_00198 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_00199 1.9e-253 comFA L Helicase C-terminal domain protein
PCDPMHHH_00200 1.1e-113 comFC S Competence protein
PCDPMHHH_00201 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PCDPMHHH_00202 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PCDPMHHH_00203 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PCDPMHHH_00204 3.1e-32 KT PspC domain protein
PCDPMHHH_00205 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PCDPMHHH_00206 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PCDPMHHH_00207 1.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PCDPMHHH_00208 1e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PCDPMHHH_00209 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PCDPMHHH_00210 1.7e-136 yrjD S LUD domain
PCDPMHHH_00211 4.9e-287 lutB C 4Fe-4S dicluster domain
PCDPMHHH_00212 1.4e-158 lutA C Cysteine-rich domain
PCDPMHHH_00213 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PCDPMHHH_00214 3.1e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PCDPMHHH_00215 2.1e-160 aatB ET PFAM extracellular solute-binding protein, family 3
PCDPMHHH_00216 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
PCDPMHHH_00217 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PCDPMHHH_00218 2.3e-116 yfbR S HD containing hydrolase-like enzyme
PCDPMHHH_00219 1.5e-13
PCDPMHHH_00220 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PCDPMHHH_00221 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PCDPMHHH_00222 2.4e-245 steT E amino acid
PCDPMHHH_00223 9.2e-161 rapZ S Displays ATPase and GTPase activities
PCDPMHHH_00224 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PCDPMHHH_00225 4.5e-169 whiA K May be required for sporulation
PCDPMHHH_00227 8.8e-15
PCDPMHHH_00228 8.8e-243 glpT G Major Facilitator Superfamily
PCDPMHHH_00229 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PCDPMHHH_00231 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PCDPMHHH_00232 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PCDPMHHH_00233 1.4e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PCDPMHHH_00234 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PCDPMHHH_00235 9.2e-248 yifK E Amino acid permease
PCDPMHHH_00236 3.6e-293 clcA P chloride
PCDPMHHH_00237 1.8e-34 secG U Preprotein translocase
PCDPMHHH_00238 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
PCDPMHHH_00239 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PCDPMHHH_00240 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PCDPMHHH_00241 6.3e-105 yxjI
PCDPMHHH_00242 2e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PCDPMHHH_00243 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PCDPMHHH_00244 2.2e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PCDPMHHH_00245 1.8e-87 K Acetyltransferase (GNAT) domain
PCDPMHHH_00246 6.8e-77 S PAS domain
PCDPMHHH_00247 2.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
PCDPMHHH_00248 3.6e-168 murB 1.3.1.98 M Cell wall formation
PCDPMHHH_00249 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCDPMHHH_00250 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PCDPMHHH_00251 3.1e-248 fucP G Major Facilitator Superfamily
PCDPMHHH_00252 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PCDPMHHH_00253 2e-126 ybbR S YbbR-like protein
PCDPMHHH_00254 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PCDPMHHH_00255 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PCDPMHHH_00256 4.8e-51
PCDPMHHH_00257 0.0 oatA I Acyltransferase
PCDPMHHH_00258 2.3e-81 K Transcriptional regulator
PCDPMHHH_00259 2.3e-145 XK27_02985 S Cof-like hydrolase
PCDPMHHH_00260 1.8e-78 lytE M Lysin motif
PCDPMHHH_00262 3.6e-134 K response regulator
PCDPMHHH_00263 2.4e-273 yclK 2.7.13.3 T Histidine kinase
PCDPMHHH_00264 2.6e-155 glcU U sugar transport
PCDPMHHH_00265 3.4e-101 lacA 2.3.1.79 S Transferase hexapeptide repeat
PCDPMHHH_00266 6.5e-262 pgi 5.3.1.9 G Belongs to the GPI family
PCDPMHHH_00267 1.3e-28
PCDPMHHH_00268 2.5e-217 xylR GK ROK family
PCDPMHHH_00270 3.7e-260 xylT EGP Major facilitator Superfamily
PCDPMHHH_00271 1.1e-172 rhaS2 K Transcriptional regulator, AraC family
PCDPMHHH_00272 2.8e-290 xynT G MFS/sugar transport protein
PCDPMHHH_00273 0.0 3.2.1.55 GH51 G Right handed beta helix region
PCDPMHHH_00274 8e-136 xylR GK ROK family
PCDPMHHH_00275 3.3e-237 xynP G MFS/sugar transport protein
PCDPMHHH_00276 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
PCDPMHHH_00277 7.6e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
PCDPMHHH_00278 4.8e-290 xylB 2.7.1.17 G Belongs to the FGGY kinase family
PCDPMHHH_00279 0.0 3.2.1.21 GH3 G hydrolase, family 3
PCDPMHHH_00280 3.7e-236 G Major Facilitator
PCDPMHHH_00281 0.0 3.2.1.177 GH31 G Glycosyl hydrolases family 31
PCDPMHHH_00282 3e-64 3.2.1.23 K helix_turn_helix, arabinose operon control protein
PCDPMHHH_00283 6.2e-154 KT YcbB domain
PCDPMHHH_00284 5.8e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PCDPMHHH_00285 5.6e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
PCDPMHHH_00286 3.9e-162 EG EamA-like transporter family
PCDPMHHH_00287 1.3e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PCDPMHHH_00288 1.2e-40 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PCDPMHHH_00289 2.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PCDPMHHH_00290 0.0 copA 3.6.3.54 P P-type ATPase
PCDPMHHH_00291 2e-88
PCDPMHHH_00293 3.6e-57
PCDPMHHH_00294 5.7e-254 yjcE P Sodium proton antiporter
PCDPMHHH_00296 1.3e-90
PCDPMHHH_00297 0.0 M domain protein
PCDPMHHH_00298 5.8e-21
PCDPMHHH_00299 4.1e-192 ampC V Beta-lactamase
PCDPMHHH_00300 3.5e-238 arcA 3.5.3.6 E Arginine
PCDPMHHH_00301 2.7e-79 argR K Regulates arginine biosynthesis genes
PCDPMHHH_00302 2.8e-260 E Arginine ornithine antiporter
PCDPMHHH_00303 5.5e-224 arcD U Amino acid permease
PCDPMHHH_00304 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
PCDPMHHH_00305 5.8e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
PCDPMHHH_00306 6e-108 tdk 2.7.1.21 F thymidine kinase
PCDPMHHH_00307 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PCDPMHHH_00308 2.7e-168 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PCDPMHHH_00309 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PCDPMHHH_00310 2.5e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PCDPMHHH_00311 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PCDPMHHH_00312 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCDPMHHH_00313 1.5e-192 yibE S overlaps another CDS with the same product name
PCDPMHHH_00314 2.2e-129 yibF S overlaps another CDS with the same product name
PCDPMHHH_00315 5.9e-233 pyrP F Permease
PCDPMHHH_00316 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
PCDPMHHH_00317 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PCDPMHHH_00318 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PCDPMHHH_00319 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PCDPMHHH_00320 8.9e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PCDPMHHH_00321 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PCDPMHHH_00322 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PCDPMHHH_00323 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PCDPMHHH_00324 1.9e-253 comFA L Helicase C-terminal domain protein
PCDPMHHH_00325 1.1e-113 comFC S Competence protein
PCDPMHHH_00326 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PCDPMHHH_00327 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PCDPMHHH_00328 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PCDPMHHH_00329 3.1e-32 KT PspC domain protein
PCDPMHHH_00330 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PCDPMHHH_00331 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PCDPMHHH_00332 1.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PCDPMHHH_00333 1e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PCDPMHHH_00334 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PCDPMHHH_00335 1.7e-136 yrjD S LUD domain
PCDPMHHH_00336 4.9e-287 lutB C 4Fe-4S dicluster domain
PCDPMHHH_00337 1.4e-158 lutA C Cysteine-rich domain
PCDPMHHH_00338 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PCDPMHHH_00339 3.1e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PCDPMHHH_00340 2.1e-160 aatB ET PFAM extracellular solute-binding protein, family 3
PCDPMHHH_00341 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
PCDPMHHH_00342 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PCDPMHHH_00343 2.3e-116 yfbR S HD containing hydrolase-like enzyme
PCDPMHHH_00344 1.5e-13
PCDPMHHH_00345 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PCDPMHHH_00346 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PCDPMHHH_00347 2.4e-245 steT E amino acid
PCDPMHHH_00348 9.2e-161 rapZ S Displays ATPase and GTPase activities
PCDPMHHH_00349 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PCDPMHHH_00350 4.5e-169 whiA K May be required for sporulation
PCDPMHHH_00352 8.8e-15
PCDPMHHH_00353 8.8e-243 glpT G Major Facilitator Superfamily
PCDPMHHH_00354 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PCDPMHHH_00355 1.9e-145 L Transposase
PCDPMHHH_00356 6.2e-235 L Transposase
PCDPMHHH_00357 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PCDPMHHH_00358 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PCDPMHHH_00359 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
PCDPMHHH_00360 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCDPMHHH_00361 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCDPMHHH_00362 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PCDPMHHH_00363 1.7e-34 yaaA S S4 domain protein YaaA
PCDPMHHH_00364 1.1e-125 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
PCDPMHHH_00365 1.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PCDPMHHH_00366 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PCDPMHHH_00367 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PCDPMHHH_00368 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PCDPMHHH_00369 1e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PCDPMHHH_00370 2.1e-132 jag S R3H domain protein
PCDPMHHH_00371 1.6e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PCDPMHHH_00372 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PCDPMHHH_00373 0.0 asnB 6.3.5.4 E Asparagine synthase
PCDPMHHH_00374 7.6e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PCDPMHHH_00375 1.4e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
PCDPMHHH_00376 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PCDPMHHH_00377 1.7e-87 2.3.1.183 M Acetyltransferase GNAT family
PCDPMHHH_00378 4.5e-160 S reductase
PCDPMHHH_00380 8.2e-42 M Glycosyl transferases group 1
PCDPMHHH_00381 5.3e-48 M Glycosyl transferases group 1
PCDPMHHH_00382 4.2e-168 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PCDPMHHH_00383 1.3e-145 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PCDPMHHH_00384 1.2e-125 S Alpha/beta hydrolase of unknown function (DUF915)
PCDPMHHH_00385 2.4e-300 S amidohydrolase
PCDPMHHH_00386 1.3e-260 K Aminotransferase class I and II
PCDPMHHH_00387 1.7e-120 azlC E azaleucine resistance protein AzlC
PCDPMHHH_00388 3.2e-50 azlD E Branched-chain amino acid transport
PCDPMHHH_00389 1.4e-121 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
PCDPMHHH_00390 6.5e-33
PCDPMHHH_00391 1.1e-26
PCDPMHHH_00392 1.5e-150 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
PCDPMHHH_00393 8.8e-89 K Bacterial regulatory proteins, tetR family
PCDPMHHH_00394 2.9e-183 ybhR V ABC transporter
PCDPMHHH_00395 4e-125 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
PCDPMHHH_00396 5e-116 S GyrI-like small molecule binding domain
PCDPMHHH_00397 2.7e-123 yhiD S MgtC family
PCDPMHHH_00398 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PCDPMHHH_00399 6.7e-195 V Beta-lactamase
PCDPMHHH_00400 4.4e-55 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PCDPMHHH_00401 3.5e-88 XK27_08850 J Aminoacyl-tRNA editing domain
PCDPMHHH_00402 5.9e-119 K LytTr DNA-binding domain
PCDPMHHH_00403 7.7e-217 2.7.13.3 T GHKL domain
PCDPMHHH_00407 1.8e-119 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
PCDPMHHH_00408 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_00409 4.2e-40
PCDPMHHH_00410 1.5e-291 lacS G Transporter
PCDPMHHH_00411 3.3e-129 ltrA S Bacterial low temperature requirement A protein (LtrA)
PCDPMHHH_00412 3.3e-80 uspA T universal stress protein
PCDPMHHH_00413 5.6e-80 K AsnC family
PCDPMHHH_00414 5.7e-231 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PCDPMHHH_00415 6.6e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
PCDPMHHH_00416 4.1e-181 galR K Transcriptional regulator
PCDPMHHH_00417 1.2e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PCDPMHHH_00418 6.5e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PCDPMHHH_00419 7.1e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PCDPMHHH_00420 1.8e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
PCDPMHHH_00421 6.3e-93 yxkA S Phosphatidylethanolamine-binding protein
PCDPMHHH_00422 9.1e-36
PCDPMHHH_00423 3.5e-52
PCDPMHHH_00424 5.1e-204
PCDPMHHH_00425 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PCDPMHHH_00426 2e-135 pnuC H nicotinamide mononucleotide transporter
PCDPMHHH_00427 3e-156 ytbE 1.1.1.346 S Aldo keto reductase
PCDPMHHH_00428 7.5e-126 K response regulator
PCDPMHHH_00429 1.5e-183 T PhoQ Sensor
PCDPMHHH_00430 5.4e-133 macB2 V ABC transporter, ATP-binding protein
PCDPMHHH_00431 0.0 ysaB V FtsX-like permease family
PCDPMHHH_00432 1.8e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PCDPMHHH_00433 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PCDPMHHH_00434 1.4e-53 K helix_turn_helix, mercury resistance
PCDPMHHH_00435 8.4e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCDPMHHH_00436 3.3e-198 EGP Major facilitator Superfamily
PCDPMHHH_00437 7.9e-88 ymdB S Macro domain protein
PCDPMHHH_00438 9.3e-110 K Helix-turn-helix domain
PCDPMHHH_00439 0.0 pepO 3.4.24.71 O Peptidase family M13
PCDPMHHH_00440 4.6e-48
PCDPMHHH_00441 3.1e-237 S Putative metallopeptidase domain
PCDPMHHH_00442 1.7e-202 3.1.3.1 S associated with various cellular activities
PCDPMHHH_00443 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PCDPMHHH_00444 1.4e-65 yeaO S Protein of unknown function, DUF488
PCDPMHHH_00446 2.1e-115 yrkL S Flavodoxin-like fold
PCDPMHHH_00447 3.6e-54
PCDPMHHH_00448 3.3e-18 S Domain of unknown function (DUF4767)
PCDPMHHH_00449 1.1e-134 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PCDPMHHH_00450 1.1e-49
PCDPMHHH_00454 1.7e-12 K Helix-turn-helix domain
PCDPMHHH_00456 9.9e-205 nrnB S DHHA1 domain
PCDPMHHH_00457 1.1e-231 S Uncharacterized protein conserved in bacteria (DUF2325)
PCDPMHHH_00458 7.1e-248 brnQ U Component of the transport system for branched-chain amino acids
PCDPMHHH_00459 5.8e-106 NU mannosyl-glycoprotein
PCDPMHHH_00460 9.5e-141 S Putative ABC-transporter type IV
PCDPMHHH_00461 1.9e-273 S ABC transporter, ATP-binding protein
PCDPMHHH_00462 1.3e-48
PCDPMHHH_00463 6.7e-31 WQ51_00220 K Helix-turn-helix domain
PCDPMHHH_00464 3.1e-102 S Protein of unknown function (DUF3278)
PCDPMHHH_00465 3.5e-34 F Belongs to the NrdI family
PCDPMHHH_00466 1.4e-39 3.4.22.70 M Sortase family
PCDPMHHH_00468 2.6e-72 K Transcriptional regulator, TetR family
PCDPMHHH_00469 7.7e-74 M PFAM NLP P60 protein
PCDPMHHH_00470 2.4e-181 ABC-SBP S ABC transporter
PCDPMHHH_00471 1.5e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PCDPMHHH_00472 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
PCDPMHHH_00473 3.1e-93 P Cadmium resistance transporter
PCDPMHHH_00474 8.9e-56 K Transcriptional regulator, ArsR family
PCDPMHHH_00475 9.2e-237 mepA V MATE efflux family protein
PCDPMHHH_00476 2.1e-54 trxA O Belongs to the thioredoxin family
PCDPMHHH_00477 2.3e-131 terC P membrane
PCDPMHHH_00478 1.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PCDPMHHH_00479 4.8e-168 corA P CorA-like Mg2+ transporter protein
PCDPMHHH_00480 7.3e-280 pipD E Dipeptidase
PCDPMHHH_00481 1.2e-241 pbuX F xanthine permease
PCDPMHHH_00482 1.2e-250 nhaC C Na H antiporter NhaC
PCDPMHHH_00483 5.3e-284 S C4-dicarboxylate anaerobic carrier
PCDPMHHH_00484 1e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
PCDPMHHH_00485 2.4e-40
PCDPMHHH_00486 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PCDPMHHH_00487 2.6e-35 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PCDPMHHH_00488 2e-109 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PCDPMHHH_00489 2.2e-158 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PCDPMHHH_00490 1.4e-34
PCDPMHHH_00491 2.3e-162 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PCDPMHHH_00492 1.3e-12 ydiN 5.4.99.5 G Major Facilitator
PCDPMHHH_00493 1.1e-53 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PCDPMHHH_00494 1.3e-127 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PCDPMHHH_00495 5.6e-132 ydiN G Major Facilitator Superfamily
PCDPMHHH_00496 4.2e-206 gldA 1.1.1.6 C dehydrogenase
PCDPMHHH_00497 8e-125 S Alpha beta hydrolase
PCDPMHHH_00498 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PCDPMHHH_00499 1.4e-101
PCDPMHHH_00501 5.2e-124 yciB M ErfK YbiS YcfS YnhG
PCDPMHHH_00502 3.5e-263 S Putative peptidoglycan binding domain
PCDPMHHH_00503 6e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PCDPMHHH_00504 9.1e-89
PCDPMHHH_00505 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
PCDPMHHH_00506 2.4e-215 yttB EGP Major facilitator Superfamily
PCDPMHHH_00507 2.5e-107
PCDPMHHH_00508 1e-24
PCDPMHHH_00509 5.1e-173 scrR K Transcriptional regulator, LacI family
PCDPMHHH_00510 2.6e-239 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PCDPMHHH_00511 4.1e-50 czrA K Transcriptional regulator, ArsR family
PCDPMHHH_00512 1e-37
PCDPMHHH_00513 0.0 yhcA V ABC transporter, ATP-binding protein
PCDPMHHH_00514 3.7e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PCDPMHHH_00515 4e-174 hrtB V ABC transporter permease
PCDPMHHH_00516 2.6e-86 ygfC K transcriptional regulator (TetR family)
PCDPMHHH_00517 6.4e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
PCDPMHHH_00518 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
PCDPMHHH_00519 5.6e-36
PCDPMHHH_00520 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PCDPMHHH_00522 1.4e-226 yxiO S Vacuole effluxer Atg22 like
PCDPMHHH_00523 1.2e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
PCDPMHHH_00524 4.1e-240 E amino acid
PCDPMHHH_00525 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PCDPMHHH_00526 5.7e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
PCDPMHHH_00527 7.8e-41 S Cytochrome B5
PCDPMHHH_00528 5.4e-09 S Cytochrome B5
PCDPMHHH_00529 2.4e-39 S Cytochrome B5
PCDPMHHH_00530 6.4e-78 elaA S Gnat family
PCDPMHHH_00531 9.2e-121 GM NmrA-like family
PCDPMHHH_00532 5.3e-50 hxlR K Transcriptional regulator, HxlR family
PCDPMHHH_00533 4.8e-108 XK27_02070 S Nitroreductase family
PCDPMHHH_00534 3.1e-83 K Transcriptional regulator, HxlR family
PCDPMHHH_00535 1.2e-233
PCDPMHHH_00536 1.8e-207 EGP Major facilitator Superfamily
PCDPMHHH_00537 2.2e-254 pepC 3.4.22.40 E aminopeptidase
PCDPMHHH_00538 8.4e-111 ylbE GM NAD dependent epimerase dehydratase family protein
PCDPMHHH_00539 0.0 pepN 3.4.11.2 E aminopeptidase
PCDPMHHH_00540 1.5e-92 folT S ECF transporter, substrate-specific component
PCDPMHHH_00541 5.4e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
PCDPMHHH_00542 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PCDPMHHH_00543 1.2e-118 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
PCDPMHHH_00544 1.2e-200 2.7.7.65 T GGDEF domain
PCDPMHHH_00545 4.3e-86
PCDPMHHH_00546 1.7e-254 pgaC GT2 M Glycosyl transferase
PCDPMHHH_00547 2.4e-142 T EAL domain
PCDPMHHH_00548 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
PCDPMHHH_00549 4.4e-64 yneR
PCDPMHHH_00550 1.2e-112 GM NAD(P)H-binding
PCDPMHHH_00551 9.8e-187 S membrane
PCDPMHHH_00552 1.8e-104 K Transcriptional regulator C-terminal region
PCDPMHHH_00553 1.9e-161 akr5f 1.1.1.346 S reductase
PCDPMHHH_00554 6.2e-133 K Transcriptional regulator
PCDPMHHH_00555 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
PCDPMHHH_00556 6.1e-188
PCDPMHHH_00558 1.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PCDPMHHH_00560 3.7e-221 S cog cog1373
PCDPMHHH_00561 5.7e-177 coaA 2.7.1.33 F Pantothenic acid kinase
PCDPMHHH_00562 2.6e-16
PCDPMHHH_00566 6.5e-41 K LytTr DNA-binding domain
PCDPMHHH_00567 2.2e-37 2.7.13.3 T GHKL domain
PCDPMHHH_00569 3.2e-50 mesE M Transport protein ComB
PCDPMHHH_00570 1.1e-228 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PCDPMHHH_00571 5e-133 L Transposase DDE domain
PCDPMHHH_00572 5.9e-26 L Transposase DDE domain
PCDPMHHH_00573 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PCDPMHHH_00574 9.2e-161 EG EamA-like transporter family
PCDPMHHH_00575 4.5e-255 nox C NADH oxidase
PCDPMHHH_00576 1.6e-244 nox C NADH oxidase
PCDPMHHH_00577 0.0 helD 3.6.4.12 L DNA helicase
PCDPMHHH_00578 6.8e-116 dedA S SNARE associated Golgi protein
PCDPMHHH_00579 5.5e-126 3.1.3.73 G phosphoglycerate mutase
PCDPMHHH_00580 1.1e-226 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PCDPMHHH_00581 2e-31 S Transglycosylase associated protein
PCDPMHHH_00583 2.7e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCDPMHHH_00584 1.2e-217 V domain protein
PCDPMHHH_00585 1.6e-94 K Transcriptional regulator (TetR family)
PCDPMHHH_00586 4.4e-39 pspC KT PspC domain protein
PCDPMHHH_00587 4.9e-151
PCDPMHHH_00588 3.1e-17 3.2.1.14 GH18
PCDPMHHH_00589 1.5e-82 zur P Belongs to the Fur family
PCDPMHHH_00590 5.8e-103 gmk2 2.7.4.8 F Guanylate kinase
PCDPMHHH_00591 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PCDPMHHH_00592 1.8e-254 yfnA E Amino Acid
PCDPMHHH_00593 1.9e-234 EGP Sugar (and other) transporter
PCDPMHHH_00594 5.6e-231
PCDPMHHH_00595 7.3e-208 potD P ABC transporter
PCDPMHHH_00596 4.9e-140 potC P ABC transporter permease
PCDPMHHH_00597 1.3e-145 potB P ABC transporter permease
PCDPMHHH_00598 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PCDPMHHH_00599 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PCDPMHHH_00600 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PCDPMHHH_00601 0.0 pacL 3.6.3.8 P P-type ATPase
PCDPMHHH_00602 2.6e-85 dps P Belongs to the Dps family
PCDPMHHH_00603 2.1e-255 yagE E amino acid
PCDPMHHH_00604 9.7e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PCDPMHHH_00605 2.1e-115 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PCDPMHHH_00606 1.8e-148 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PCDPMHHH_00609 6.7e-191
PCDPMHHH_00610 4.1e-130 agrA K LytTr DNA-binding domain
PCDPMHHH_00611 4.3e-197 T GHKL domain
PCDPMHHH_00612 1.8e-130 S Double zinc ribbon
PCDPMHHH_00613 6.4e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
PCDPMHHH_00614 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
PCDPMHHH_00615 2.5e-138 IQ KR domain
PCDPMHHH_00616 1.3e-132 S membrane transporter protein
PCDPMHHH_00617 9.3e-98 S ABC-type cobalt transport system, permease component
PCDPMHHH_00618 3.1e-251 cbiO1 S ABC transporter, ATP-binding protein
PCDPMHHH_00619 1.7e-111 P Cobalt transport protein
PCDPMHHH_00620 1.6e-52 yvlA
PCDPMHHH_00621 0.0 yjcE P Sodium proton antiporter
PCDPMHHH_00622 1.8e-234 L transposase IS116 IS110 IS902 family protein
PCDPMHHH_00623 8.4e-52 ypaA S Protein of unknown function (DUF1304)
PCDPMHHH_00624 2.1e-190 D Alpha beta
PCDPMHHH_00625 1e-72 K Transcriptional regulator
PCDPMHHH_00626 7e-161
PCDPMHHH_00627 1e-176 1.6.5.5 C Zinc-binding dehydrogenase
PCDPMHHH_00628 5e-257 G PTS system Galactitol-specific IIC component
PCDPMHHH_00629 1.8e-212 EGP Major facilitator Superfamily
PCDPMHHH_00630 1.3e-133 V ABC transporter
PCDPMHHH_00631 1.4e-106
PCDPMHHH_00632 6.1e-126 I Serine aminopeptidase, S33
PCDPMHHH_00633 9e-26 K ArsR family transcriptional regulator
PCDPMHHH_00634 5.2e-14
PCDPMHHH_00635 7.1e-63
PCDPMHHH_00636 2.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
PCDPMHHH_00637 5.1e-81 uspA T universal stress protein
PCDPMHHH_00638 0.0 tetP J elongation factor G
PCDPMHHH_00639 2.3e-167 GK ROK family
PCDPMHHH_00640 2e-242 brnQ U Component of the transport system for branched-chain amino acids
PCDPMHHH_00641 1.3e-81 tlpA2 L Transposase IS200 like
PCDPMHHH_00642 2.1e-238 L transposase, IS605 OrfB family
PCDPMHHH_00643 4.5e-140 aroD S Serine hydrolase (FSH1)
PCDPMHHH_00644 3.6e-244 yagE E amino acid
PCDPMHHH_00645 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PCDPMHHH_00646 4.3e-135 gntR K UbiC transcription regulator-associated domain protein
PCDPMHHH_00647 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PCDPMHHH_00648 1.4e-283 pipD E Dipeptidase
PCDPMHHH_00649 0.0 yfiC V ABC transporter
PCDPMHHH_00650 4.8e-310 lmrA V ABC transporter, ATP-binding protein
PCDPMHHH_00651 1.1e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCDPMHHH_00652 1.6e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PCDPMHHH_00653 8.8e-162
PCDPMHHH_00654 4.3e-155 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PCDPMHHH_00655 6.5e-175 S AI-2E family transporter
PCDPMHHH_00656 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
PCDPMHHH_00657 6.6e-78 yybA 2.3.1.57 K Transcriptional regulator
PCDPMHHH_00658 2.3e-90 M1-874 K Domain of unknown function (DUF1836)
PCDPMHHH_00659 8.8e-90 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
PCDPMHHH_00660 2.3e-156 ypdB V (ABC) transporter
PCDPMHHH_00661 3.3e-242 yhdP S Transporter associated domain
PCDPMHHH_00662 2.9e-84 nrdI F Belongs to the NrdI family
PCDPMHHH_00663 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
PCDPMHHH_00664 3.1e-193 yeaN P Transporter, major facilitator family protein
PCDPMHHH_00665 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PCDPMHHH_00666 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PCDPMHHH_00667 5.6e-56 L Resolvase, N terminal domain
PCDPMHHH_00668 4.1e-07
PCDPMHHH_00670 8.2e-86 L Belongs to the 'phage' integrase family
PCDPMHHH_00671 5.6e-220 oxlT P Major Facilitator Superfamily
PCDPMHHH_00672 4.6e-160 spoU 2.1.1.185 J Methyltransferase
PCDPMHHH_00673 2.6e-128 S PFAM Archaeal ATPase
PCDPMHHH_00674 6.9e-100 crp_2 K Cyclic nucleotide-binding domain
PCDPMHHH_00675 1.3e-128 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
PCDPMHHH_00676 9.1e-138 pnuC H nicotinamide mononucleotide transporter
PCDPMHHH_00677 8.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PCDPMHHH_00678 3e-99 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PCDPMHHH_00679 7.3e-98 ywlG S Belongs to the UPF0340 family
PCDPMHHH_00680 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
PCDPMHHH_00681 6.3e-228 E Amino acid permease
PCDPMHHH_00682 1e-193 nhaC C Na H antiporter NhaC
PCDPMHHH_00683 4.3e-220 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PCDPMHHH_00684 8.4e-194 EGP Major facilitator Superfamily
PCDPMHHH_00685 1.9e-120 M Lysin motif
PCDPMHHH_00686 1.2e-79
PCDPMHHH_00687 3.4e-94 wecD3 K PFAM GCN5-related N-acetyltransferase
PCDPMHHH_00688 3e-207 cytX U Belongs to the purine-cytosine permease (2.A.39) family
PCDPMHHH_00689 4.3e-13
PCDPMHHH_00690 5.5e-77 S Domain of unknown function (DUF4767)
PCDPMHHH_00691 3e-198 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PCDPMHHH_00692 2.7e-114 S Membrane
PCDPMHHH_00693 1.7e-125 O Zinc-dependent metalloprotease
PCDPMHHH_00694 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PCDPMHHH_00695 3.4e-155 metQ_4 P Belongs to the nlpA lipoprotein family
PCDPMHHH_00697 0.0 UW LPXTG-motif cell wall anchor domain protein
PCDPMHHH_00698 0.0 UW LPXTG-motif cell wall anchor domain protein
PCDPMHHH_00699 6.2e-235 L Transposase
PCDPMHHH_00700 1.3e-224 L Transposase
PCDPMHHH_00701 1.3e-10 L Resolvase, N terminal domain
PCDPMHHH_00702 2e-09 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PCDPMHHH_00706 3.6e-46 S Protein of unknown function (DUF4065)
PCDPMHHH_00707 1.2e-32 S Region found in RelA / SpoT proteins
PCDPMHHH_00708 8.6e-43 V Abi-like protein
PCDPMHHH_00709 1.6e-47 ebh D nuclear chromosome segregation
PCDPMHHH_00710 1.9e-13 K Cro/C1-type HTH DNA-binding domain
PCDPMHHH_00711 1.7e-06
PCDPMHHH_00712 6.9e-43 hxlR K Transcriptional regulator, HxlR family
PCDPMHHH_00715 1.1e-54
PCDPMHHH_00716 3.1e-113 frnE Q DSBA-like thioredoxin domain
PCDPMHHH_00717 1.3e-162 I alpha/beta hydrolase fold
PCDPMHHH_00718 8.5e-20 K Helix-turn-helix XRE-family like proteins
PCDPMHHH_00719 1.1e-35 S Phage derived protein Gp49-like (DUF891)
PCDPMHHH_00721 9.8e-48 yrvD S Pfam:DUF1049
PCDPMHHH_00722 2.8e-151 3.1.3.102, 3.1.3.104 S hydrolase
PCDPMHHH_00723 2.1e-90 ntd 2.4.2.6 F Nucleoside
PCDPMHHH_00724 4.8e-20
PCDPMHHH_00725 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
PCDPMHHH_00726 2.8e-114 yviA S Protein of unknown function (DUF421)
PCDPMHHH_00727 3.1e-72 S Protein of unknown function (DUF3290)
PCDPMHHH_00728 2.6e-39 ybaN S Protein of unknown function (DUF454)
PCDPMHHH_00729 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCDPMHHH_00730 2.5e-150 endA V DNA/RNA non-specific endonuclease
PCDPMHHH_00731 3e-254 yifK E Amino acid permease
PCDPMHHH_00733 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PCDPMHHH_00734 4.6e-230 N Uncharacterized conserved protein (DUF2075)
PCDPMHHH_00735 1.8e-122 S SNARE associated Golgi protein
PCDPMHHH_00736 0.0 uvrA3 L excinuclease ABC, A subunit
PCDPMHHH_00737 1.7e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCDPMHHH_00738 1.9e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCDPMHHH_00739 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PCDPMHHH_00740 6.6e-145 S DUF218 domain
PCDPMHHH_00741 0.0 ubiB S ABC1 family
PCDPMHHH_00742 8.5e-246 yhdP S Transporter associated domain
PCDPMHHH_00743 7.2e-74 copY K Copper transport repressor CopY TcrY
PCDPMHHH_00744 1.6e-244 EGP Major facilitator Superfamily
PCDPMHHH_00745 1.7e-73 yeaL S UPF0756 membrane protein
PCDPMHHH_00746 1.9e-07 yphH S Cupin domain
PCDPMHHH_00747 1.2e-82 C Flavodoxin
PCDPMHHH_00748 1.2e-160 K LysR substrate binding domain protein
PCDPMHHH_00749 7.2e-169 1.1.1.346 C Aldo keto reductase
PCDPMHHH_00750 2.1e-39 gcvR T Belongs to the UPF0237 family
PCDPMHHH_00751 6.7e-243 XK27_08635 S UPF0210 protein
PCDPMHHH_00752 2.4e-95 K Acetyltransferase (GNAT) domain
PCDPMHHH_00753 1.2e-160 S Alpha beta hydrolase
PCDPMHHH_00754 1.3e-159 gspA M family 8
PCDPMHHH_00755 8.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PCDPMHHH_00756 1.8e-92
PCDPMHHH_00757 6.4e-162 degV S EDD domain protein, DegV family
PCDPMHHH_00758 0.0 FbpA K Fibronectin-binding protein
PCDPMHHH_00759 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PCDPMHHH_00760 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
PCDPMHHH_00761 3.1e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PCDPMHHH_00762 2.2e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PCDPMHHH_00763 1.5e-65 esbA S Family of unknown function (DUF5322)
PCDPMHHH_00764 8.4e-69 rnhA 3.1.26.4 L Ribonuclease HI
PCDPMHHH_00765 2.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PCDPMHHH_00766 1.2e-82 F Belongs to the NrdI family
PCDPMHHH_00767 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PCDPMHHH_00768 1.1e-101 ypsA S Belongs to the UPF0398 family
PCDPMHHH_00769 7.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PCDPMHHH_00770 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PCDPMHHH_00771 1.4e-162 EG EamA-like transporter family
PCDPMHHH_00772 7.3e-124 dnaD L DnaD domain protein
PCDPMHHH_00773 2.9e-85 ypmB S Protein conserved in bacteria
PCDPMHHH_00774 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PCDPMHHH_00775 2e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PCDPMHHH_00776 5.5e-162 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PCDPMHHH_00777 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PCDPMHHH_00778 1.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PCDPMHHH_00779 3.8e-87 S Protein of unknown function (DUF1440)
PCDPMHHH_00780 0.0 rafA 3.2.1.22 G alpha-galactosidase
PCDPMHHH_00781 2.7e-188 galR K Periplasmic binding protein-like domain
PCDPMHHH_00782 9.9e-171 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PCDPMHHH_00783 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PCDPMHHH_00784 1.3e-123 lrgB M LrgB-like family
PCDPMHHH_00785 1.9e-66 lrgA S LrgA family
PCDPMHHH_00786 3.3e-127 lytT K response regulator receiver
PCDPMHHH_00787 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
PCDPMHHH_00788 6.8e-148 f42a O Band 7 protein
PCDPMHHH_00789 4.2e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PCDPMHHH_00790 1.9e-155 yitU 3.1.3.104 S hydrolase
PCDPMHHH_00791 6e-38 S Cytochrome B5
PCDPMHHH_00792 1.3e-114 nreC K PFAM regulatory protein LuxR
PCDPMHHH_00793 7.2e-161 hipB K Helix-turn-helix
PCDPMHHH_00794 2.8e-57 yitW S Iron-sulfur cluster assembly protein
PCDPMHHH_00795 3e-270 sufB O assembly protein SufB
PCDPMHHH_00796 3.2e-80 nifU C SUF system FeS assembly protein, NifU family
PCDPMHHH_00797 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PCDPMHHH_00798 3.6e-238 sufD O FeS assembly protein SufD
PCDPMHHH_00799 1.9e-144 sufC O FeS assembly ATPase SufC
PCDPMHHH_00800 1.2e-31 feoA P FeoA domain
PCDPMHHH_00801 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PCDPMHHH_00802 4e-270 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PCDPMHHH_00803 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PCDPMHHH_00804 1.6e-64 ydiI Q Thioesterase superfamily
PCDPMHHH_00805 5.4e-109 yvrI K sigma factor activity
PCDPMHHH_00806 5.6e-201 G Transporter, major facilitator family protein
PCDPMHHH_00807 0.0 S Bacterial membrane protein YfhO
PCDPMHHH_00808 3.9e-104 T Ion transport 2 domain protein
PCDPMHHH_00809 8.8e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PCDPMHHH_00810 2.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PCDPMHHH_00811 2.8e-100 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PCDPMHHH_00812 2.1e-199 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PCDPMHHH_00813 5.1e-181 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PCDPMHHH_00815 8.9e-199 nupC F Na+ dependent nucleoside transporter C-terminus
PCDPMHHH_00816 2.2e-178 1.1.1.1 C alcohol dehydrogenase
PCDPMHHH_00817 4.4e-72 S Membrane
PCDPMHHH_00818 2.6e-118 trpF 5.3.1.24 E belongs to the TrpF family
PCDPMHHH_00819 1.1e-148 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G Phosphomethylpyrimidine kinase
PCDPMHHH_00820 8.7e-145 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 GK Winged helix-turn-helix DNA-binding
PCDPMHHH_00822 6.7e-78 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PCDPMHHH_00824 0.0 L PLD-like domain
PCDPMHHH_00825 5.5e-21
PCDPMHHH_00827 6.5e-32 higA K addiction module antidote protein HigA
PCDPMHHH_00829 1e-52 yhaI S Protein of unknown function (DUF805)
PCDPMHHH_00830 2.2e-44
PCDPMHHH_00831 0.0 nylA 3.5.1.4 J Belongs to the amidase family
PCDPMHHH_00832 4.2e-47
PCDPMHHH_00833 2.2e-96 K Acetyltransferase (GNAT) domain
PCDPMHHH_00834 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_00835 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_00836 1.9e-253 comFA L Helicase C-terminal domain protein
PCDPMHHH_00837 1.1e-113 comFC S Competence protein
PCDPMHHH_00838 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PCDPMHHH_00839 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PCDPMHHH_00840 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PCDPMHHH_00841 3.1e-32 KT PspC domain protein
PCDPMHHH_00842 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PCDPMHHH_00843 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PCDPMHHH_00844 1.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PCDPMHHH_00845 1e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PCDPMHHH_00846 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PCDPMHHH_00847 1.7e-136 yrjD S LUD domain
PCDPMHHH_00848 4.9e-287 lutB C 4Fe-4S dicluster domain
PCDPMHHH_00849 1.4e-158 lutA C Cysteine-rich domain
PCDPMHHH_00850 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PCDPMHHH_00851 3.1e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PCDPMHHH_00852 2.1e-160 aatB ET PFAM extracellular solute-binding protein, family 3
PCDPMHHH_00853 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
PCDPMHHH_00854 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PCDPMHHH_00855 2.3e-116 yfbR S HD containing hydrolase-like enzyme
PCDPMHHH_00856 1.5e-13
PCDPMHHH_00857 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PCDPMHHH_00858 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PCDPMHHH_00859 2.4e-245 steT E amino acid
PCDPMHHH_00860 9.2e-161 rapZ S Displays ATPase and GTPase activities
PCDPMHHH_00861 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PCDPMHHH_00862 4.5e-169 whiA K May be required for sporulation
PCDPMHHH_00864 8.8e-15
PCDPMHHH_00865 8.8e-243 glpT G Major Facilitator Superfamily
PCDPMHHH_00866 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PCDPMHHH_00867 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_00871 6.3e-10 K Helix-turn-helix XRE-family like proteins
PCDPMHHH_00872 1.8e-79 3.4.21.88 K Peptidase S24-like
PCDPMHHH_00873 3.1e-12
PCDPMHHH_00874 6e-15
PCDPMHHH_00875 7.6e-23 S Protein of unknown function (DUF4231)
PCDPMHHH_00876 5e-70 S MTH538 TIR-like domain (DUF1863)
PCDPMHHH_00877 4.2e-24
PCDPMHHH_00878 1.3e-223 3.6.4.12 L Belongs to the 'phage' integrase family
PCDPMHHH_00879 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PCDPMHHH_00880 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PCDPMHHH_00881 0.0 dnaK O Heat shock 70 kDa protein
PCDPMHHH_00882 2.7e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PCDPMHHH_00883 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PCDPMHHH_00884 6.5e-63
PCDPMHHH_00885 5.9e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PCDPMHHH_00886 2.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PCDPMHHH_00887 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PCDPMHHH_00888 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PCDPMHHH_00889 4.5e-49 ylxQ J ribosomal protein
PCDPMHHH_00890 1e-44 ylxR K Protein of unknown function (DUF448)
PCDPMHHH_00891 1e-215 nusA K Participates in both transcription termination and antitermination
PCDPMHHH_00892 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
PCDPMHHH_00893 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCDPMHHH_00894 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PCDPMHHH_00895 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PCDPMHHH_00896 3.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
PCDPMHHH_00897 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PCDPMHHH_00898 2.2e-229 L transposase, IS605 OrfB family
PCDPMHHH_00899 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PCDPMHHH_00900 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PCDPMHHH_00901 4.2e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PCDPMHHH_00902 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
PCDPMHHH_00903 8.3e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCDPMHHH_00904 1.6e-48 yazA L GIY-YIG catalytic domain protein
PCDPMHHH_00905 7.8e-140 yabB 2.1.1.223 L Methyltransferase small domain
PCDPMHHH_00906 1.6e-117 plsC 2.3.1.51 I Acyltransferase
PCDPMHHH_00907 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
PCDPMHHH_00908 1.3e-35 ynzC S UPF0291 protein
PCDPMHHH_00909 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PCDPMHHH_00910 2.9e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PCDPMHHH_00911 1.5e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PCDPMHHH_00913 8.7e-16
PCDPMHHH_00914 9e-20 S Phage gp6-like head-tail connector protein
PCDPMHHH_00915 1.2e-187 S Caudovirus prohead serine protease
PCDPMHHH_00916 4.2e-142 S Phage portal protein
PCDPMHHH_00917 1e-203 terL S overlaps another CDS with the same product name
PCDPMHHH_00918 3.2e-22 terS L Phage terminase, small subunit
PCDPMHHH_00919 4e-22 L HNH endonuclease
PCDPMHHH_00920 4.4e-14 S head-tail joining protein
PCDPMHHH_00922 1.1e-91 S Phage plasmid primase, P4
PCDPMHHH_00923 6.8e-44 L Primase C terminal 1 (PriCT-1)
PCDPMHHH_00930 6.2e-07 S Helix-turn-helix domain
PCDPMHHH_00931 1e-07 K Transcriptional regulator
PCDPMHHH_00932 6e-56 sip L Belongs to the 'phage' integrase family
PCDPMHHH_00933 2.5e-88
PCDPMHHH_00934 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PCDPMHHH_00935 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PCDPMHHH_00936 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PCDPMHHH_00937 1.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PCDPMHHH_00938 1.2e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PCDPMHHH_00939 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PCDPMHHH_00940 4.9e-08
PCDPMHHH_00941 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PCDPMHHH_00942 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
PCDPMHHH_00943 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PCDPMHHH_00944 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PCDPMHHH_00945 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PCDPMHHH_00946 2.1e-163 S Tetratricopeptide repeat
PCDPMHHH_00947 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PCDPMHHH_00948 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PCDPMHHH_00949 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
PCDPMHHH_00950 2.8e-148 holA 2.7.7.7 L DNA polymerase III delta subunit
PCDPMHHH_00951 0.0 comEC S Competence protein ComEC
PCDPMHHH_00952 1.2e-88 comEB 3.5.4.12 F ComE operon protein 2
PCDPMHHH_00953 3.2e-78 comEA L Competence protein ComEA
PCDPMHHH_00954 4.6e-199 ylbL T Belongs to the peptidase S16 family
PCDPMHHH_00955 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PCDPMHHH_00956 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PCDPMHHH_00957 1.1e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PCDPMHHH_00958 2.7e-222 ftsW D Belongs to the SEDS family
PCDPMHHH_00959 0.0 typA T GTP-binding protein TypA
PCDPMHHH_00960 9.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PCDPMHHH_00961 3e-47 yktA S Belongs to the UPF0223 family
PCDPMHHH_00962 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
PCDPMHHH_00963 1.8e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PCDPMHHH_00964 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PCDPMHHH_00965 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PCDPMHHH_00966 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PCDPMHHH_00967 3.6e-82
PCDPMHHH_00968 9.8e-32 ykzG S Belongs to the UPF0356 family
PCDPMHHH_00969 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
PCDPMHHH_00970 5.7e-29
PCDPMHHH_00971 1.8e-129 mltD CBM50 M NlpC P60 family protein
PCDPMHHH_00973 2.2e-57
PCDPMHHH_00974 2.8e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PCDPMHHH_00975 1.7e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PCDPMHHH_00976 1.6e-219 patA 2.6.1.1 E Aminotransferase
PCDPMHHH_00977 6.2e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PCDPMHHH_00978 2.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PCDPMHHH_00979 2.1e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PCDPMHHH_00980 1.3e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PCDPMHHH_00981 1.2e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PCDPMHHH_00982 5.7e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
PCDPMHHH_00983 2.9e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PCDPMHHH_00984 1.7e-30 UW LPXTG-motif cell wall anchor domain protein
PCDPMHHH_00985 2.2e-56 infB UW LPXTG-motif cell wall anchor domain protein
PCDPMHHH_00986 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_00987 5.1e-206 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
PCDPMHHH_00988 3.7e-298 L PFAM plasmid pRiA4b ORF-3 family protein
PCDPMHHH_00989 1.7e-265 S Uncharacterized protein conserved in bacteria (DUF2252)
PCDPMHHH_00992 5.8e-22
PCDPMHHH_00993 2.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PCDPMHHH_00994 6.7e-75
PCDPMHHH_00995 3e-221 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PCDPMHHH_00996 3.5e-130 ponA V Beta-lactamase enzyme family
PCDPMHHH_00997 6.5e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
PCDPMHHH_00998 1.4e-215 uhpT EGP Major facilitator Superfamily
PCDPMHHH_00999 5.8e-255 ytjP 3.5.1.18 E Dipeptidase
PCDPMHHH_01000 2.2e-274 arcD S C4-dicarboxylate anaerobic carrier
PCDPMHHH_01001 1.1e-178 yfeX P Peroxidase
PCDPMHHH_01002 8.2e-170 lsa S ABC transporter
PCDPMHHH_01003 6.5e-136 I alpha/beta hydrolase fold
PCDPMHHH_01004 2.1e-180 MA20_14895 S Conserved hypothetical protein 698
PCDPMHHH_01005 3.2e-95 S NADPH-dependent FMN reductase
PCDPMHHH_01006 2.5e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PCDPMHHH_01007 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PCDPMHHH_01008 1e-232 mntH P H( )-stimulated, divalent metal cation uptake system
PCDPMHHH_01011 1.8e-44 K Cro/C1-type HTH DNA-binding domain
PCDPMHHH_01012 3.5e-81 Q Methyltransferase
PCDPMHHH_01013 1.4e-116 ktrA P domain protein
PCDPMHHH_01014 2.6e-239 ktrB P Potassium uptake protein
PCDPMHHH_01015 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
PCDPMHHH_01016 2.8e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PCDPMHHH_01017 2.2e-218 G Glycosyl hydrolases family 8
PCDPMHHH_01018 2.5e-242 ydaM M Glycosyl transferase
PCDPMHHH_01019 3.7e-138
PCDPMHHH_01020 3.9e-125 phoU P Plays a role in the regulation of phosphate uptake
PCDPMHHH_01021 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PCDPMHHH_01022 6.5e-154 pstA P Phosphate transport system permease protein PstA
PCDPMHHH_01023 6.6e-154 pstC P probably responsible for the translocation of the substrate across the membrane
PCDPMHHH_01024 2.5e-158 pstS P Phosphate
PCDPMHHH_01025 9.6e-132 K Transcriptional regulatory protein, C-terminal domain protein
PCDPMHHH_01026 2.3e-136 cbiO P ABC transporter
PCDPMHHH_01027 3.8e-135 P Cobalt transport protein
PCDPMHHH_01028 2.2e-182 nikMN P PDGLE domain
PCDPMHHH_01029 6.9e-74 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCDPMHHH_01030 4.9e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCDPMHHH_01031 3.7e-162 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PCDPMHHH_01032 4.7e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PCDPMHHH_01033 1.6e-131 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PCDPMHHH_01034 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PCDPMHHH_01035 0.0 ureC 3.5.1.5 E Amidohydrolase family
PCDPMHHH_01036 2.9e-63 ureB 3.5.1.5 E Urease beta subunit
PCDPMHHH_01037 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
PCDPMHHH_01038 5.6e-97 ureI S AmiS/UreI family transporter
PCDPMHHH_01039 3.1e-223 P ammonium transporter
PCDPMHHH_01040 9.7e-17 K Transcriptional regulator, HxlR family
PCDPMHHH_01041 5.8e-183
PCDPMHHH_01042 4.4e-97 2.3.1.128 K acetyltransferase
PCDPMHHH_01043 2.7e-145 manA 5.3.1.8 G mannose-6-phosphate isomerase
PCDPMHHH_01044 4.7e-160 K LysR substrate binding domain
PCDPMHHH_01045 6.3e-207 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PCDPMHHH_01046 3.3e-64 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PCDPMHHH_01047 2.2e-180
PCDPMHHH_01048 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PCDPMHHH_01049 1.4e-182 S Phosphotransferase system, EIIC
PCDPMHHH_01050 0.0 UW LPXTG-motif cell wall anchor domain protein
PCDPMHHH_01051 6.2e-235 L Transposase
PCDPMHHH_01052 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_01053 2.5e-107 yvyE 3.4.13.9 S YigZ family
PCDPMHHH_01054 1.7e-24 K transcriptional regulator
PCDPMHHH_01055 1.8e-39 C nitroreductase
PCDPMHHH_01056 1e-238 EGP Major facilitator Superfamily
PCDPMHHH_01057 3.3e-68 rmaI K Transcriptional regulator
PCDPMHHH_01058 9.2e-40
PCDPMHHH_01059 0.0 ydaO E amino acid
PCDPMHHH_01060 6.2e-304 ybeC E amino acid
PCDPMHHH_01061 1.9e-83 S Aminoacyl-tRNA editing domain
PCDPMHHH_01062 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PCDPMHHH_01063 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PCDPMHHH_01064 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PCDPMHHH_01065 0.0 uup S ABC transporter, ATP-binding protein
PCDPMHHH_01066 2.6e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PCDPMHHH_01067 1.1e-225 mtnE 2.6.1.83 E Aminotransferase
PCDPMHHH_01068 3.5e-143 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PCDPMHHH_01069 1.7e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PCDPMHHH_01070 1.1e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PCDPMHHH_01071 9.4e-133 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PCDPMHHH_01072 1.6e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PCDPMHHH_01073 9.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PCDPMHHH_01074 1.7e-112 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PCDPMHHH_01075 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PCDPMHHH_01076 2.5e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PCDPMHHH_01077 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PCDPMHHH_01078 1.2e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PCDPMHHH_01079 3.6e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
PCDPMHHH_01080 4.7e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PCDPMHHH_01081 5.9e-58 yabA L Involved in initiation control of chromosome replication
PCDPMHHH_01082 8.2e-185 holB 2.7.7.7 L DNA polymerase III
PCDPMHHH_01083 7.6e-52 yaaQ S Cyclic-di-AMP receptor
PCDPMHHH_01084 1.9e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PCDPMHHH_01085 9.7e-39 S Protein of unknown function (DUF2508)
PCDPMHHH_01086 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PCDPMHHH_01087 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PCDPMHHH_01088 2.4e-299 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCDPMHHH_01089 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PCDPMHHH_01090 3.4e-35 nrdH O Glutaredoxin
PCDPMHHH_01091 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCDPMHHH_01092 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCDPMHHH_01093 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PCDPMHHH_01094 1e-224 L Transposase
PCDPMHHH_01095 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_01097 1e-14
PCDPMHHH_01100 5e-109 L DnaD domain protein
PCDPMHHH_01101 4.7e-131 L Belongs to the 'phage' integrase family
PCDPMHHH_01102 5.8e-123 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
PCDPMHHH_01104 4.8e-70
PCDPMHHH_01105 1.4e-133
PCDPMHHH_01107 7.2e-17
PCDPMHHH_01111 2.7e-82 arpU S Phage transcriptional regulator, ArpU family
PCDPMHHH_01113 1.2e-08
PCDPMHHH_01114 8.6e-156 L HNH nucleases
PCDPMHHH_01115 6.9e-78 terS L Phage terminase, small subunit
PCDPMHHH_01116 0.0 terL S overlaps another CDS with the same product name
PCDPMHHH_01120 1.4e-239 S Phage portal protein
PCDPMHHH_01121 3.7e-114 pi136 S Caudovirus prohead serine protease
PCDPMHHH_01122 7e-201 S Phage capsid family
PCDPMHHH_01123 3.7e-67 S Phage gp6-like head-tail connector protein
PCDPMHHH_01124 1.5e-39 S Phage head-tail joining protein
PCDPMHHH_01125 7.2e-62 S Bacteriophage HK97-gp10, putative tail-component
PCDPMHHH_01126 1.1e-74
PCDPMHHH_01127 3.8e-116
PCDPMHHH_01128 4.6e-58
PCDPMHHH_01129 4.6e-24
PCDPMHHH_01130 0.0 M Phage tail tape measure protein TP901
PCDPMHHH_01131 1.1e-158 S Phage tail protein
PCDPMHHH_01132 6.2e-258 3.4.24.40 M Peptidase family M23
PCDPMHHH_01134 1e-95 S Domain of unknown function (DUF2479)
PCDPMHHH_01138 5.3e-15
PCDPMHHH_01139 2.2e-62 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PCDPMHHH_01140 3.1e-206 3.5.1.104 M hydrolase, family 25
PCDPMHHH_01142 3.7e-276 pipD E Dipeptidase
PCDPMHHH_01143 1.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PCDPMHHH_01144 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PCDPMHHH_01146 2.8e-57
PCDPMHHH_01147 4.8e-179 prmA J Ribosomal protein L11 methyltransferase
PCDPMHHH_01148 5.5e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PCDPMHHH_01149 1.3e-51
PCDPMHHH_01150 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PCDPMHHH_01151 5.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PCDPMHHH_01152 1.4e-166 yniA G Phosphotransferase enzyme family
PCDPMHHH_01153 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PCDPMHHH_01154 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCDPMHHH_01155 8.2e-266 glnPH2 P ABC transporter permease
PCDPMHHH_01156 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PCDPMHHH_01157 2.1e-68 yqeY S YqeY-like protein
PCDPMHHH_01158 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PCDPMHHH_01159 2.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PCDPMHHH_01160 4.1e-264 argH 4.3.2.1 E argininosuccinate lyase
PCDPMHHH_01161 9.6e-90 bioY S BioY family
PCDPMHHH_01162 9.3e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PCDPMHHH_01163 1.5e-183 phoH T phosphate starvation-inducible protein PhoH
PCDPMHHH_01164 2.1e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PCDPMHHH_01165 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PCDPMHHH_01166 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PCDPMHHH_01167 2.6e-146 recO L Involved in DNA repair and RecF pathway recombination
PCDPMHHH_01168 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PCDPMHHH_01169 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PCDPMHHH_01170 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PCDPMHHH_01171 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PCDPMHHH_01172 7e-220 patA 2.6.1.1 E Aminotransferase
PCDPMHHH_01173 1.6e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
PCDPMHHH_01174 2.1e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PCDPMHHH_01175 1.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PCDPMHHH_01176 2.3e-30 S Protein of unknown function (DUF2929)
PCDPMHHH_01177 0.0 dnaE 2.7.7.7 L DNA polymerase
PCDPMHHH_01178 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PCDPMHHH_01179 1.3e-167 cvfB S S1 domain
PCDPMHHH_01180 1.1e-164 xerD D recombinase XerD
PCDPMHHH_01181 4.3e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PCDPMHHH_01182 1.7e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PCDPMHHH_01183 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PCDPMHHH_01184 5.8e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PCDPMHHH_01185 2.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PCDPMHHH_01186 1.2e-191 ypbB 5.1.3.1 S Helix-turn-helix domain
PCDPMHHH_01187 6.9e-270 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PCDPMHHH_01188 8.5e-14 M Lysin motif
PCDPMHHH_01189 4.9e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PCDPMHHH_01190 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
PCDPMHHH_01191 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PCDPMHHH_01192 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PCDPMHHH_01193 7.4e-236 S Tetratricopeptide repeat protein
PCDPMHHH_01194 6.7e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PCDPMHHH_01195 0.0 yfmR S ABC transporter, ATP-binding protein
PCDPMHHH_01196 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PCDPMHHH_01197 1.8e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PCDPMHHH_01198 3.4e-112 hlyIII S protein, hemolysin III
PCDPMHHH_01199 2.2e-151 DegV S EDD domain protein, DegV family
PCDPMHHH_01200 1e-170 ypmR E lipolytic protein G-D-S-L family
PCDPMHHH_01201 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PCDPMHHH_01202 4.4e-35 yozE S Belongs to the UPF0346 family
PCDPMHHH_01203 8.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PCDPMHHH_01204 1.4e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PCDPMHHH_01205 4.6e-160 dprA LU DNA protecting protein DprA
PCDPMHHH_01206 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PCDPMHHH_01207 3.5e-168 lacX 5.1.3.3 G Aldose 1-epimerase
PCDPMHHH_01208 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PCDPMHHH_01209 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PCDPMHHH_01210 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PCDPMHHH_01211 1.9e-83 F NUDIX domain
PCDPMHHH_01212 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
PCDPMHHH_01213 1.2e-67 yqkB S Belongs to the HesB IscA family
PCDPMHHH_01214 2.7e-49
PCDPMHHH_01216 2.7e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PCDPMHHH_01217 1.3e-61 asp S Asp23 family, cell envelope-related function
PCDPMHHH_01218 2.3e-24
PCDPMHHH_01219 7.2e-95
PCDPMHHH_01220 1.3e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PCDPMHHH_01221 1.2e-183 K Transcriptional regulator, LacI family
PCDPMHHH_01222 1.6e-233 gntT EG Gluconate
PCDPMHHH_01223 5e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PCDPMHHH_01224 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_01225 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_01226 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PCDPMHHH_01227 1.3e-157 mleR K LysR family
PCDPMHHH_01228 1.2e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PCDPMHHH_01229 2.4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PCDPMHHH_01230 3.4e-266 frdC 1.3.5.4 C FAD binding domain
PCDPMHHH_01231 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
PCDPMHHH_01232 1e-159 mleR K LysR family
PCDPMHHH_01233 3.6e-252 yjjP S Putative threonine/serine exporter
PCDPMHHH_01234 3.3e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
PCDPMHHH_01235 2.8e-277 emrY EGP Major facilitator Superfamily
PCDPMHHH_01236 8.5e-187 I Alpha beta
PCDPMHHH_01237 2.2e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PCDPMHHH_01238 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PCDPMHHH_01240 1.9e-161 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PCDPMHHH_01241 3.3e-119 S Domain of unknown function (DUF4811)
PCDPMHHH_01242 7.2e-270 lmrB EGP Major facilitator Superfamily
PCDPMHHH_01243 4.9e-73 merR K MerR HTH family regulatory protein
PCDPMHHH_01244 5.1e-54
PCDPMHHH_01245 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PCDPMHHH_01246 9.2e-220 S CAAX protease self-immunity
PCDPMHHH_01247 1.4e-108 glnP P ABC transporter permease
PCDPMHHH_01248 3.2e-110 gluC P ABC transporter permease
PCDPMHHH_01249 2.6e-152 glnH ET ABC transporter
PCDPMHHH_01250 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCDPMHHH_01251 2.7e-82 usp1 T Belongs to the universal stress protein A family
PCDPMHHH_01252 4.9e-109 S VIT family
PCDPMHHH_01253 2.9e-117 S membrane
PCDPMHHH_01254 3.5e-166 czcD P cation diffusion facilitator family transporter
PCDPMHHH_01255 2.4e-124 sirR K iron dependent repressor
PCDPMHHH_01256 1e-30 cspC K Cold shock protein
PCDPMHHH_01257 1.4e-128 thrE S Putative threonine/serine exporter
PCDPMHHH_01258 2.1e-82 S Threonine/Serine exporter, ThrE
PCDPMHHH_01259 2.3e-119 lssY 3.6.1.27 I phosphatase
PCDPMHHH_01260 4.1e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
PCDPMHHH_01261 2.3e-276 lysP E amino acid
PCDPMHHH_01262 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PCDPMHHH_01268 2.3e-11
PCDPMHHH_01269 2.6e-180 S Hydrolases of the alpha beta superfamily
PCDPMHHH_01270 3.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
PCDPMHHH_01271 3.4e-77 ctsR K Belongs to the CtsR family
PCDPMHHH_01272 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PCDPMHHH_01273 1e-110 K Bacterial regulatory proteins, tetR family
PCDPMHHH_01274 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCDPMHHH_01275 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCDPMHHH_01276 5.3e-204 ykiI
PCDPMHHH_01277 5.7e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PCDPMHHH_01278 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PCDPMHHH_01279 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PCDPMHHH_01280 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PCDPMHHH_01281 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PCDPMHHH_01282 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PCDPMHHH_01283 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
PCDPMHHH_01284 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PCDPMHHH_01285 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PCDPMHHH_01286 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PCDPMHHH_01287 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PCDPMHHH_01288 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PCDPMHHH_01289 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PCDPMHHH_01290 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
PCDPMHHH_01291 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PCDPMHHH_01292 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PCDPMHHH_01293 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PCDPMHHH_01294 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PCDPMHHH_01295 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PCDPMHHH_01296 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PCDPMHHH_01297 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PCDPMHHH_01298 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PCDPMHHH_01299 2.9e-24 rpmD J Ribosomal protein L30
PCDPMHHH_01300 8.9e-64 rplO J Binds to the 23S rRNA
PCDPMHHH_01301 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PCDPMHHH_01302 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PCDPMHHH_01303 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PCDPMHHH_01304 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PCDPMHHH_01305 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PCDPMHHH_01306 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PCDPMHHH_01307 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCDPMHHH_01308 1.3e-61 rplQ J Ribosomal protein L17
PCDPMHHH_01309 1.5e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PCDPMHHH_01310 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PCDPMHHH_01311 1.2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PCDPMHHH_01312 3.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PCDPMHHH_01313 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PCDPMHHH_01314 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PCDPMHHH_01315 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
PCDPMHHH_01316 3.9e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PCDPMHHH_01317 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
PCDPMHHH_01318 9.4e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PCDPMHHH_01319 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCDPMHHH_01320 2.7e-39 ptsH G phosphocarrier protein HPR
PCDPMHHH_01321 2.9e-27
PCDPMHHH_01322 0.0 clpE O Belongs to the ClpA ClpB family
PCDPMHHH_01323 1.1e-99 S Pfam:DUF3816
PCDPMHHH_01324 1.4e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PCDPMHHH_01325 6e-115
PCDPMHHH_01326 1.9e-158 V ABC transporter, ATP-binding protein
PCDPMHHH_01327 9.3e-65 gntR1 K Transcriptional regulator, GntR family
PCDPMHHH_01328 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_01329 5.1e-23
PCDPMHHH_01330 3.9e-208
PCDPMHHH_01331 1.3e-151 3.1.3.73 G Belongs to the phosphoglycerate mutase family
PCDPMHHH_01332 3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PCDPMHHH_01333 6.3e-102 fic D Fic/DOC family
PCDPMHHH_01334 1.6e-70
PCDPMHHH_01335 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
PCDPMHHH_01336 4.2e-92 L nuclease
PCDPMHHH_01337 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PCDPMHHH_01338 1.9e-206 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PCDPMHHH_01339 4.3e-177 M Glycosyl hydrolases family 25
PCDPMHHH_01340 5.9e-143 ywqE 3.1.3.48 GM PHP domain protein
PCDPMHHH_01342 1e-37
PCDPMHHH_01343 3.3e-67 T Toxin-antitoxin system, toxin component, MazF family
PCDPMHHH_01345 1.1e-251 mmuP E amino acid
PCDPMHHH_01346 1.4e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PCDPMHHH_01348 1.7e-59 S Protein of unknown function (DUF4065)
PCDPMHHH_01350 7.1e-43 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PCDPMHHH_01351 4.7e-25
PCDPMHHH_01353 6.9e-46 L Reverse transcriptase (RNA-dependent DNA polymerase)
PCDPMHHH_01355 3.4e-118 G Belongs to the carbohydrate kinase PfkB family
PCDPMHHH_01356 5.4e-240 F Belongs to the purine-cytosine permease (2.A.39) family
PCDPMHHH_01357 8.4e-166 yegU O ADP-ribosylglycohydrolase
PCDPMHHH_01358 4.6e-99 busR K UTRA
PCDPMHHH_01359 1.2e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
PCDPMHHH_01360 3.8e-151 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PCDPMHHH_01361 4.3e-66 M Glycosyltransferase sugar-binding region containing DXD motif
PCDPMHHH_01362 3.9e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PCDPMHHH_01363 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PCDPMHHH_01364 5.8e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PCDPMHHH_01365 1e-129 S polysaccharide biosynthetic process
PCDPMHHH_01366 1.4e-27
PCDPMHHH_01367 9.9e-53 cps1B GT2,GT4 M Glycosyl transferases group 1
PCDPMHHH_01368 3.7e-29 GT2 S Glycosyltransferase, group 2 family protein
PCDPMHHH_01369 1.8e-65
PCDPMHHH_01370 2.1e-61 lsgF M Glycosyl transferase family 2
PCDPMHHH_01371 8.1e-53 pglC M Bacterial sugar transferase
PCDPMHHH_01372 7.5e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PCDPMHHH_01373 3.5e-144 epsB M biosynthesis protein
PCDPMHHH_01374 1.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PCDPMHHH_01375 2.1e-67 K Transcriptional regulator, HxlR family
PCDPMHHH_01376 5.9e-129
PCDPMHHH_01377 2.2e-102 K DNA-templated transcription, initiation
PCDPMHHH_01378 6.2e-35
PCDPMHHH_01379 6.9e-84
PCDPMHHH_01380 8.1e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PCDPMHHH_01381 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PCDPMHHH_01382 0.0 yjbQ P TrkA C-terminal domain protein
PCDPMHHH_01383 1.5e-269 pipD E Dipeptidase
PCDPMHHH_01388 3.7e-19
PCDPMHHH_01389 1.3e-263 dtpT U amino acid peptide transporter
PCDPMHHH_01390 1e-153 yjjH S Calcineurin-like phosphoesterase
PCDPMHHH_01393 8.8e-108
PCDPMHHH_01394 1.4e-248 EGP Major facilitator Superfamily
PCDPMHHH_01395 4.1e-303 aspT P Predicted Permease Membrane Region
PCDPMHHH_01396 6.3e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PCDPMHHH_01397 2.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
PCDPMHHH_01398 1.1e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PCDPMHHH_01399 8.2e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PCDPMHHH_01400 0.0 yhgF K Tex-like protein N-terminal domain protein
PCDPMHHH_01401 1.4e-83 ydcK S Belongs to the SprT family
PCDPMHHH_01403 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
PCDPMHHH_01404 1.4e-259 hsdM 2.1.1.72 V type I restriction-modification system
PCDPMHHH_01405 8.1e-110 3.1.21.3 V Type I restriction modification DNA specificity domain
PCDPMHHH_01406 1.9e-65 3.1.21.3 V Type I restriction modification DNA specificity domain
PCDPMHHH_01407 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PCDPMHHH_01408 4.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PCDPMHHH_01409 0.0 S Bacterial membrane protein, YfhO
PCDPMHHH_01410 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PCDPMHHH_01411 7e-169 I alpha/beta hydrolase fold
PCDPMHHH_01412 2.2e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PCDPMHHH_01413 1.4e-119 tcyB E ABC transporter
PCDPMHHH_01414 3.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCDPMHHH_01415 5.3e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PCDPMHHH_01416 9.4e-63 ydzE EG EamA-like transporter family
PCDPMHHH_01417 1.7e-267 pepC 3.4.22.40 E Peptidase C1-like family
PCDPMHHH_01418 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PCDPMHHH_01419 2.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
PCDPMHHH_01420 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PCDPMHHH_01421 1.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PCDPMHHH_01422 1.7e-207 yacL S domain protein
PCDPMHHH_01423 8.5e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PCDPMHHH_01424 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PCDPMHHH_01425 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCDPMHHH_01426 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PCDPMHHH_01427 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PCDPMHHH_01428 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
PCDPMHHH_01429 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PCDPMHHH_01430 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PCDPMHHH_01431 1.6e-227 aadAT EK Aminotransferase, class I
PCDPMHHH_01433 6.9e-245 M Glycosyl transferase family group 2
PCDPMHHH_01434 1.2e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PCDPMHHH_01435 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PCDPMHHH_01436 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PCDPMHHH_01437 7.7e-48
PCDPMHHH_01439 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PCDPMHHH_01440 1.2e-55 K transcriptional regulator PadR family
PCDPMHHH_01441 1.7e-73 XK27_06920 S Protein of unknown function (DUF1700)
PCDPMHHH_01442 1.7e-131 S Putative adhesin
PCDPMHHH_01443 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PCDPMHHH_01444 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PCDPMHHH_01445 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
PCDPMHHH_01446 4.7e-114 yjbH Q Thioredoxin
PCDPMHHH_01447 1.7e-262 pipD E Dipeptidase
PCDPMHHH_01448 8.9e-201 coiA 3.6.4.12 S Competence protein
PCDPMHHH_01449 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PCDPMHHH_01450 6.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PCDPMHHH_01451 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PCDPMHHH_01453 3.8e-111 K Transcriptional regulator, TetR family
PCDPMHHH_01455 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PCDPMHHH_01456 3.6e-87
PCDPMHHH_01457 2.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PCDPMHHH_01458 8.4e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PCDPMHHH_01459 7.1e-261 nox C NADH oxidase
PCDPMHHH_01460 3.9e-87 hmpT S ECF-type riboflavin transporter, S component
PCDPMHHH_01461 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
PCDPMHHH_01462 2.3e-167 yvgN C Aldo keto reductase
PCDPMHHH_01463 7.8e-137 puuD S peptidase C26
PCDPMHHH_01464 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PCDPMHHH_01465 4.2e-209 yfeO P Voltage gated chloride channel
PCDPMHHH_01466 1.7e-224 sptS 2.7.13.3 T Histidine kinase
PCDPMHHH_01467 5.8e-115 K response regulator
PCDPMHHH_01468 7.4e-88 2.7.6.5 T Region found in RelA / SpoT proteins
PCDPMHHH_01469 5.4e-69
PCDPMHHH_01470 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PCDPMHHH_01471 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PCDPMHHH_01472 2.1e-257 malT G Major Facilitator
PCDPMHHH_01473 8e-208 phbA 2.3.1.9 I Belongs to the thiolase family
PCDPMHHH_01474 1e-173 malR K Transcriptional regulator, LacI family
PCDPMHHH_01475 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PCDPMHHH_01476 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PCDPMHHH_01477 1.4e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCDPMHHH_01478 6.3e-105 wecD3 K PFAM GCN5-related N-acetyltransferase
PCDPMHHH_01480 0.0 clpL O associated with various cellular activities
PCDPMHHH_01481 2.7e-32
PCDPMHHH_01482 1.1e-217 patA 2.6.1.1 E Aminotransferase
PCDPMHHH_01483 1.1e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCDPMHHH_01484 1.1e-74 osmC O OsmC-like protein
PCDPMHHH_01487 6.7e-107 K LytTr DNA-binding domain
PCDPMHHH_01488 3e-147 2.7.13.3 T GHKL domain
PCDPMHHH_01491 4.6e-263 S Putative peptidoglycan binding domain
PCDPMHHH_01492 1.3e-34
PCDPMHHH_01493 8.6e-213 bacI V MacB-like periplasmic core domain
PCDPMHHH_01494 2.6e-129 V ABC transporter
PCDPMHHH_01495 6.8e-145 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCDPMHHH_01496 6.8e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PCDPMHHH_01497 9.2e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PCDPMHHH_01498 1.2e-148 E Glyoxalase-like domain
PCDPMHHH_01499 7.5e-155 glcU U sugar transport
PCDPMHHH_01500 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
PCDPMHHH_01501 1.1e-95 S reductase
PCDPMHHH_01503 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PCDPMHHH_01504 1.5e-178 ABC-SBP S ABC transporter
PCDPMHHH_01505 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PCDPMHHH_01506 4.1e-218 htrA 3.4.21.107 O serine protease
PCDPMHHH_01507 4.5e-154 vicX 3.1.26.11 S domain protein
PCDPMHHH_01508 4.2e-150 yycI S YycH protein
PCDPMHHH_01509 6e-249 yycH S YycH protein
PCDPMHHH_01510 0.0 vicK 2.7.13.3 T Histidine kinase
PCDPMHHH_01511 3.1e-130 K response regulator
PCDPMHHH_01513 4.8e-311 lmrA 3.6.3.44 V ABC transporter
PCDPMHHH_01514 8.1e-73 K helix_turn_helix multiple antibiotic resistance protein
PCDPMHHH_01516 5.1e-123 Z012_01130 S Fic/DOC family
PCDPMHHH_01517 4.3e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
PCDPMHHH_01518 1.2e-60
PCDPMHHH_01519 1.1e-207 yttB EGP Major facilitator Superfamily
PCDPMHHH_01520 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PCDPMHHH_01521 2e-74 rplI J Binds to the 23S rRNA
PCDPMHHH_01522 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PCDPMHHH_01523 6.2e-235 L Transposase
PCDPMHHH_01525 3.9e-12
PCDPMHHH_01526 1.3e-218 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PCDPMHHH_01527 6.9e-297 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PCDPMHHH_01528 1.4e-264 glnA 6.3.1.2 E glutamine synthetase
PCDPMHHH_01529 9.1e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PCDPMHHH_01530 5.9e-22 S Protein of unknown function (DUF3042)
PCDPMHHH_01531 3.4e-67 yqhL P Rhodanese-like protein
PCDPMHHH_01532 1.5e-183 glk 2.7.1.2 G Glucokinase
PCDPMHHH_01533 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
PCDPMHHH_01534 1.6e-112 gluP 3.4.21.105 S Peptidase, S54 family
PCDPMHHH_01535 3.4e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PCDPMHHH_01536 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PCDPMHHH_01537 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PCDPMHHH_01538 0.0 S membrane
PCDPMHHH_01539 2.6e-70 yneR S Belongs to the HesB IscA family
PCDPMHHH_01540 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PCDPMHHH_01541 7.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
PCDPMHHH_01542 4.3e-107 rlpA M PFAM NLP P60 protein
PCDPMHHH_01543 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PCDPMHHH_01544 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PCDPMHHH_01545 1.1e-58 yodB K Transcriptional regulator, HxlR family
PCDPMHHH_01546 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PCDPMHHH_01547 2.2e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCDPMHHH_01548 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_01549 4.6e-120 S Hydrolases of the alpha beta superfamily
PCDPMHHH_01550 2.4e-87 lacA S transferase hexapeptide repeat
PCDPMHHH_01551 1.2e-152 K Transcriptional regulator
PCDPMHHH_01552 2.1e-16
PCDPMHHH_01553 3.5e-85 C Flavodoxin
PCDPMHHH_01554 3.6e-165 S Oxidoreductase, aldo keto reductase family protein
PCDPMHHH_01555 8.6e-56 yphJ 4.1.1.44 S decarboxylase
PCDPMHHH_01556 1.3e-98 M Protein of unknown function (DUF3737)
PCDPMHHH_01557 3.1e-220 4.4.1.8 E Aminotransferase, class I
PCDPMHHH_01558 2.8e-124 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
PCDPMHHH_01559 3.9e-131 K Transcriptional regulator
PCDPMHHH_01560 6.8e-92 S Peptidase propeptide and YPEB domain
PCDPMHHH_01561 2.2e-230 T GHKL domain
PCDPMHHH_01562 1.2e-120 T Transcriptional regulatory protein, C terminal
PCDPMHHH_01563 1.2e-161 mleP3 S Membrane transport protein
PCDPMHHH_01564 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_01565 1e-141 L PFAM transposase IS116 IS110 IS902
PCDPMHHH_01566 2.6e-221 M ErfK YbiS YcfS YnhG
PCDPMHHH_01567 1.5e-16 S Domain of unknown function (DUF4767)
PCDPMHHH_01568 0.0 M NlpC/P60 family
PCDPMHHH_01569 9.6e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PCDPMHHH_01570 1.5e-224 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PCDPMHHH_01571 4.3e-163 yueF S AI-2E family transporter
PCDPMHHH_01572 3.5e-284 G Peptidase_C39 like family
PCDPMHHH_01573 7.3e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PCDPMHHH_01574 1.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PCDPMHHH_01575 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PCDPMHHH_01576 2.6e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PCDPMHHH_01577 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PCDPMHHH_01579 5.2e-139 S Psort location CytoplasmicMembrane, score
PCDPMHHH_01580 8.3e-18 cps3I G Acyltransferase family
PCDPMHHH_01581 2e-82 S Bacterial membrane protein, YfhO
PCDPMHHH_01582 2e-24
PCDPMHHH_01583 1.7e-89 S Glycosyltransferase like family
PCDPMHHH_01584 7.2e-88 M Domain of unknown function (DUF4422)
PCDPMHHH_01585 3.1e-41 M biosynthesis protein
PCDPMHHH_01586 2.2e-93 cps3F
PCDPMHHH_01587 4.2e-103 M Glycosyltransferase like family 2
PCDPMHHH_01588 3.4e-111 S Glycosyltransferase like family 2
PCDPMHHH_01589 3.7e-78 rgpB GT2 M Glycosyl transferase family 2
PCDPMHHH_01590 1.1e-216 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PCDPMHHH_01591 9.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
PCDPMHHH_01592 2.1e-25
PCDPMHHH_01593 0.0 G Peptidase_C39 like family
PCDPMHHH_01594 0.0 2.7.7.6 M Peptidase family M23
PCDPMHHH_01595 8.9e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PCDPMHHH_01596 3.7e-113 cps1D M Domain of unknown function (DUF4422)
PCDPMHHH_01597 5.2e-100 rfbP M Bacterial sugar transferase
PCDPMHHH_01598 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
PCDPMHHH_01599 4.9e-31
PCDPMHHH_01600 6.6e-34 S Protein of unknown function (DUF2922)
PCDPMHHH_01601 1.6e-152 yihY S Belongs to the UPF0761 family
PCDPMHHH_01602 5.3e-281 yjeM E Amino Acid
PCDPMHHH_01603 6.1e-255 E Arginine ornithine antiporter
PCDPMHHH_01604 1.1e-219 arcT 2.6.1.1 E Aminotransferase
PCDPMHHH_01605 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
PCDPMHHH_01606 2.3e-78 fld C Flavodoxin
PCDPMHHH_01607 1.8e-67 gtcA S Teichoic acid glycosylation protein
PCDPMHHH_01608 1.4e-17
PCDPMHHH_01609 3.9e-21
PCDPMHHH_01610 2.2e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PCDPMHHH_01612 2.5e-231 yfmL L DEAD DEAH box helicase
PCDPMHHH_01613 4.5e-191 mocA S Oxidoreductase
PCDPMHHH_01614 9.1e-62 S Domain of unknown function (DUF4828)
PCDPMHHH_01615 5.9e-111 yvdD 3.2.2.10 S Belongs to the LOG family
PCDPMHHH_01616 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PCDPMHHH_01617 1.3e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PCDPMHHH_01618 6.3e-201 S Protein of unknown function (DUF3114)
PCDPMHHH_01619 2.2e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
PCDPMHHH_01620 1.9e-119 ybhL S Belongs to the BI1 family
PCDPMHHH_01621 1.4e-207 yhjX P Major Facilitator Superfamily
PCDPMHHH_01622 1.8e-21
PCDPMHHH_01623 6.4e-78 K LytTr DNA-binding domain
PCDPMHHH_01624 7.3e-69 S Protein of unknown function (DUF3021)
PCDPMHHH_01625 1.6e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
PCDPMHHH_01626 2e-71 XK27_00915 C Luciferase-like monooxygenase
PCDPMHHH_01627 1.2e-230 L transposase, IS605 OrfB family
PCDPMHHH_01628 5e-78 tlpA2 L Transposase IS200 like
PCDPMHHH_01629 2.8e-29 ogt 2.1.1.63 L Methyltransferase
PCDPMHHH_01630 6.3e-122 pnb C nitroreductase
PCDPMHHH_01631 1.2e-89
PCDPMHHH_01632 7e-90 S B3 4 domain
PCDPMHHH_01633 5.6e-250 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
PCDPMHHH_01634 1.2e-206 amtB P ammonium transporter
PCDPMHHH_01635 1.1e-86 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PCDPMHHH_01636 1.1e-47
PCDPMHHH_01637 4.3e-195 S PFAM Archaeal ATPase
PCDPMHHH_01638 4.2e-61 XK27_04080 H Riboflavin biosynthesis protein RibD
PCDPMHHH_01639 9.7e-172 L Plasmid pRiA4b ORF-3-like protein
PCDPMHHH_01642 5.1e-82 padR K Transcriptional regulator PadR-like family
PCDPMHHH_01643 3.3e-247 norB EGP Major Facilitator
PCDPMHHH_01644 5.7e-106 1.6.5.2 S NADPH-dependent FMN reductase
PCDPMHHH_01645 1.1e-87 K Bacterial regulatory proteins, tetR family
PCDPMHHH_01646 2.9e-87 entB 3.5.1.19 Q Isochorismatase family
PCDPMHHH_01647 4.4e-64 K Psort location Cytoplasmic, score
PCDPMHHH_01648 3.2e-66 yjdF S Protein of unknown function (DUF2992)
PCDPMHHH_01649 6.8e-211 norB EGP Major Facilitator
PCDPMHHH_01650 2.5e-44 K Bacterial regulatory proteins, tetR family
PCDPMHHH_01651 7.3e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCDPMHHH_01653 1e-187 yegS 2.7.1.107 G Lipid kinase
PCDPMHHH_01654 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PCDPMHHH_01655 2.7e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PCDPMHHH_01656 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PCDPMHHH_01657 1.2e-202 camS S sex pheromone
PCDPMHHH_01658 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PCDPMHHH_01659 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PCDPMHHH_01660 1.1e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PCDPMHHH_01661 1.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PCDPMHHH_01662 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
PCDPMHHH_01663 9.4e-141 IQ reductase
PCDPMHHH_01666 3.8e-111 lssY 3.6.1.27 I Acid phosphatase homologues
PCDPMHHH_01667 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
PCDPMHHH_01668 1.2e-230 clcA_2 P Chloride transporter, ClC family
PCDPMHHH_01678 3.1e-77 L PFAM Integrase catalytic region
PCDPMHHH_01680 8.1e-193 nss M transferase activity, transferring glycosyl groups
PCDPMHHH_01681 1.9e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
PCDPMHHH_01682 1.8e-289 M transferase activity, transferring glycosyl groups
PCDPMHHH_01683 6.8e-289 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
PCDPMHHH_01684 5.3e-164 asp3 S Accessory Sec secretory system ASP3
PCDPMHHH_01685 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PCDPMHHH_01686 2.9e-290 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PCDPMHHH_01687 1.9e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PCDPMHHH_01689 0.0 GT2,GT4 M Pfam:DUF1792
PCDPMHHH_01690 0.0 M family 8
PCDPMHHH_01692 4.8e-154 P Belongs to the nlpA lipoprotein family
PCDPMHHH_01693 4.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCDPMHHH_01694 1.4e-50 S Iron-sulfur cluster assembly protein
PCDPMHHH_01695 1e-151
PCDPMHHH_01696 4.1e-184
PCDPMHHH_01697 1.2e-88 dut S Protein conserved in bacteria
PCDPMHHH_01700 2.6e-112 K Transcriptional regulator
PCDPMHHH_01701 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
PCDPMHHH_01702 3.7e-54 ysxB J Cysteine protease Prp
PCDPMHHH_01703 1e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PCDPMHHH_01704 1.4e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PCDPMHHH_01705 1.9e-203 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PCDPMHHH_01706 1.3e-117 J 2'-5' RNA ligase superfamily
PCDPMHHH_01707 2.2e-70 yqhY S Asp23 family, cell envelope-related function
PCDPMHHH_01708 1.6e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PCDPMHHH_01709 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PCDPMHHH_01710 1.1e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PCDPMHHH_01711 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PCDPMHHH_01712 1.5e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PCDPMHHH_01713 4.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PCDPMHHH_01714 1.1e-77 argR K Regulates arginine biosynthesis genes
PCDPMHHH_01715 1.8e-261 recN L May be involved in recombinational repair of damaged DNA
PCDPMHHH_01716 1.7e-54
PCDPMHHH_01717 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PCDPMHHH_01718 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PCDPMHHH_01719 2.1e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PCDPMHHH_01720 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PCDPMHHH_01721 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PCDPMHHH_01722 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PCDPMHHH_01723 7.6e-132 stp 3.1.3.16 T phosphatase
PCDPMHHH_01724 0.0 KLT serine threonine protein kinase
PCDPMHHH_01725 3.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PCDPMHHH_01726 5.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PCDPMHHH_01727 2.9e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
PCDPMHHH_01728 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PCDPMHHH_01729 4.7e-58 asp S Asp23 family, cell envelope-related function
PCDPMHHH_01730 0.0 yloV S DAK2 domain fusion protein YloV
PCDPMHHH_01731 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PCDPMHHH_01732 2.3e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PCDPMHHH_01733 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCDPMHHH_01734 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PCDPMHHH_01735 0.0 smc D Required for chromosome condensation and partitioning
PCDPMHHH_01736 2.5e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PCDPMHHH_01737 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PCDPMHHH_01738 6.7e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PCDPMHHH_01739 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PCDPMHHH_01740 4.1e-40 ylqC S Belongs to the UPF0109 family
PCDPMHHH_01741 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PCDPMHHH_01742 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PCDPMHHH_01743 5.8e-261 yfnA E amino acid
PCDPMHHH_01744 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PCDPMHHH_01745 2.5e-155 L Belongs to the 'phage' integrase family
PCDPMHHH_01746 3.7e-43
PCDPMHHH_01748 2.4e-176
PCDPMHHH_01749 6.1e-45 L nuclease
PCDPMHHH_01750 2.5e-18
PCDPMHHH_01752 1.8e-09
PCDPMHHH_01753 1.7e-34
PCDPMHHH_01754 3.5e-52 S Mazg nucleotide pyrophosphohydrolase
PCDPMHHH_01755 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
PCDPMHHH_01756 3.3e-83
PCDPMHHH_01757 1.6e-188 lacR K Transcriptional regulator
PCDPMHHH_01758 0.0 lacS G Transporter
PCDPMHHH_01759 0.0 lacZ 3.2.1.23 G -beta-galactosidase
PCDPMHHH_01760 2.2e-33 ywzB S Protein of unknown function (DUF1146)
PCDPMHHH_01761 1.9e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PCDPMHHH_01762 1.9e-178 mbl D Cell shape determining protein MreB Mrl
PCDPMHHH_01763 1e-31 S Protein of unknown function (DUF2969)
PCDPMHHH_01764 1.1e-220 rodA D Belongs to the SEDS family
PCDPMHHH_01765 1.4e-47 gcvH E glycine cleavage
PCDPMHHH_01766 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PCDPMHHH_01767 3e-148 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PCDPMHHH_01768 1.2e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PCDPMHHH_01769 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
PCDPMHHH_01770 5.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PCDPMHHH_01771 2.8e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PCDPMHHH_01772 5.6e-98 maa 2.3.1.79 S Maltose O-acetyltransferase
PCDPMHHH_01773 2.7e-157 ytbE 1.1.1.346 S Aldo keto reductase
PCDPMHHH_01774 1e-204 araR K Transcriptional regulator
PCDPMHHH_01775 4.3e-83 usp6 T universal stress protein
PCDPMHHH_01776 5.7e-46
PCDPMHHH_01777 1.4e-242 rarA L recombination factor protein RarA
PCDPMHHH_01778 7.9e-85 yueI S Protein of unknown function (DUF1694)
PCDPMHHH_01779 1.5e-21
PCDPMHHH_01780 1.8e-74 4.4.1.5 E Glyoxalase
PCDPMHHH_01781 2.5e-138 S Membrane
PCDPMHHH_01782 1.5e-138 S Belongs to the UPF0246 family
PCDPMHHH_01783 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
PCDPMHHH_01784 4.4e-263 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PCDPMHHH_01785 1.8e-235 pbuG S permease
PCDPMHHH_01786 1e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PCDPMHHH_01787 4.3e-286 gadC E amino acid
PCDPMHHH_01788 8.8e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
PCDPMHHH_01789 1.7e-290 gadC E amino acid
PCDPMHHH_01790 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PCDPMHHH_01791 1.4e-250 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PCDPMHHH_01792 3.5e-216 iscS2 2.8.1.7 E Aminotransferase class V
PCDPMHHH_01793 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCDPMHHH_01794 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PCDPMHHH_01795 3.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
PCDPMHHH_01796 1.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PCDPMHHH_01797 3.5e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PCDPMHHH_01798 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PCDPMHHH_01799 2e-230 ndh 1.6.99.3 C NADH dehydrogenase
PCDPMHHH_01800 8.2e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PCDPMHHH_01801 1.8e-121 radC L DNA repair protein
PCDPMHHH_01802 1.7e-179 mreB D cell shape determining protein MreB
PCDPMHHH_01803 5.9e-152 mreC M Involved in formation and maintenance of cell shape
PCDPMHHH_01804 4.3e-92 mreD M rod shape-determining protein MreD
PCDPMHHH_01805 3.2e-102 glnP P ABC transporter permease
PCDPMHHH_01806 3.6e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCDPMHHH_01807 7.6e-160 aatB ET ABC transporter substrate-binding protein
PCDPMHHH_01808 7.8e-230 ymfF S Peptidase M16 inactive domain protein
PCDPMHHH_01809 3.5e-249 ymfH S Peptidase M16
PCDPMHHH_01810 6.3e-140 ymfM S Helix-turn-helix domain
PCDPMHHH_01811 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PCDPMHHH_01812 3.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
PCDPMHHH_01813 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PCDPMHHH_01814 2.1e-208 rny S Endoribonuclease that initiates mRNA decay
PCDPMHHH_01815 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PCDPMHHH_01816 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PCDPMHHH_01817 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PCDPMHHH_01818 1.7e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PCDPMHHH_01819 6.9e-190 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PCDPMHHH_01820 4.3e-32 yajC U Preprotein translocase
PCDPMHHH_01821 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PCDPMHHH_01822 8.3e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PCDPMHHH_01823 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PCDPMHHH_01824 4.1e-43 yrzL S Belongs to the UPF0297 family
PCDPMHHH_01825 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PCDPMHHH_01826 6.1e-48 yrzB S Belongs to the UPF0473 family
PCDPMHHH_01827 1.6e-86 cvpA S Colicin V production protein
PCDPMHHH_01828 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PCDPMHHH_01829 6.1e-54 trxA O Belongs to the thioredoxin family
PCDPMHHH_01830 1.7e-96 yslB S Protein of unknown function (DUF2507)
PCDPMHHH_01831 9.8e-141 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PCDPMHHH_01832 3.3e-101 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PCDPMHHH_01833 5.9e-94 S Phosphoesterase
PCDPMHHH_01834 5.1e-75 ykuL S (CBS) domain
PCDPMHHH_01835 1.5e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PCDPMHHH_01836 8.1e-149 ykuT M mechanosensitive ion channel
PCDPMHHH_01837 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PCDPMHHH_01838 4.9e-28
PCDPMHHH_01839 1.9e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PCDPMHHH_01840 5.5e-181 ccpA K catabolite control protein A
PCDPMHHH_01841 3.8e-135
PCDPMHHH_01842 3.8e-131 yebC K Transcriptional regulatory protein
PCDPMHHH_01843 5.1e-184 comGA NU Type II IV secretion system protein
PCDPMHHH_01844 4.6e-183 comGB NU type II secretion system
PCDPMHHH_01845 7.1e-47 comGC U competence protein ComGC
PCDPMHHH_01846 1.4e-77 NU general secretion pathway protein
PCDPMHHH_01847 1.1e-41
PCDPMHHH_01848 1.8e-69
PCDPMHHH_01850 1.9e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
PCDPMHHH_01851 4.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PCDPMHHH_01852 6.5e-113 S Calcineurin-like phosphoesterase
PCDPMHHH_01853 6e-94 yutD S Protein of unknown function (DUF1027)
PCDPMHHH_01854 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PCDPMHHH_01855 1.4e-105 S Protein of unknown function (DUF1461)
PCDPMHHH_01856 7.2e-110 dedA S SNARE-like domain protein
PCDPMHHH_01857 7.6e-31 L PFAM transposase IS200-family protein
PCDPMHHH_01858 1.4e-43 hxlR K Transcriptional regulator, HxlR family
PCDPMHHH_01859 4.7e-241 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
PCDPMHHH_01860 9.3e-130 IQ Dehydrogenase reductase
PCDPMHHH_01861 4.1e-36
PCDPMHHH_01862 3.7e-114 ywnB S NAD(P)H-binding
PCDPMHHH_01863 1.6e-38 S Cytochrome b5-like Heme/Steroid binding domain
PCDPMHHH_01864 1.2e-255 nhaC C Na H antiporter NhaC
PCDPMHHH_01865 2e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PCDPMHHH_01867 2.5e-100 ydeN S Serine hydrolase
PCDPMHHH_01868 5.9e-62 psiE S Phosphate-starvation-inducible E
PCDPMHHH_01869 9.4e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PCDPMHHH_01871 8.2e-143 K helix_turn_helix, arabinose operon control protein
PCDPMHHH_01872 5.4e-86 S Membrane
PCDPMHHH_01873 0.0 rafA 3.2.1.22 G alpha-galactosidase
PCDPMHHH_01874 4.8e-179 S Aldo keto reductase
PCDPMHHH_01875 1.7e-74 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
PCDPMHHH_01876 0.0 L Helicase C-terminal domain protein
PCDPMHHH_01878 1.3e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PCDPMHHH_01879 2.6e-52 S Sugar efflux transporter for intercellular exchange
PCDPMHHH_01880 9.2e-127
PCDPMHHH_01881 1.2e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PCDPMHHH_01882 0.0 cadA P P-type ATPase
PCDPMHHH_01883 8.5e-226 5.4.2.7 G Metalloenzyme superfamily
PCDPMHHH_01885 6.7e-156 1.6.5.2 GM NAD(P)H-binding
PCDPMHHH_01886 4e-75 K Transcriptional regulator
PCDPMHHH_01887 9.5e-161 proX M ABC transporter, substrate-binding protein, QAT family
PCDPMHHH_01888 4.8e-106 proWZ P ABC transporter permease
PCDPMHHH_01889 7.2e-141 proV E ABC transporter, ATP-binding protein
PCDPMHHH_01890 2.5e-99 proW P ABC transporter, permease protein
PCDPMHHH_01891 5.7e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PCDPMHHH_01892 5.4e-253 clcA P chloride
PCDPMHHH_01893 1.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PCDPMHHH_01894 2.2e-101 metI P ABC transporter permease
PCDPMHHH_01895 4.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCDPMHHH_01896 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
PCDPMHHH_01897 9.5e-122 scrR3 K Transcriptional regulator, LacI family
PCDPMHHH_01898 1.4e-156 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PCDPMHHH_01899 2.6e-42 S Sugar efflux transporter for intercellular exchange
PCDPMHHH_01900 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PCDPMHHH_01901 3.7e-221 norA EGP Major facilitator Superfamily
PCDPMHHH_01902 1.9e-43 1.3.5.4 S FMN binding
PCDPMHHH_01903 3.2e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PCDPMHHH_01904 5.2e-265 yfnA E amino acid
PCDPMHHH_01905 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PCDPMHHH_01907 6.9e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PCDPMHHH_01908 0.0 helD 3.6.4.12 L DNA helicase
PCDPMHHH_01909 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
PCDPMHHH_01910 1.5e-183 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
PCDPMHHH_01911 2.2e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PCDPMHHH_01912 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PCDPMHHH_01913 5.7e-228 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PCDPMHHH_01914 1.4e-178
PCDPMHHH_01915 5.2e-130 cobB K SIR2 family
PCDPMHHH_01917 5.8e-160 yunF F Protein of unknown function DUF72
PCDPMHHH_01918 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCDPMHHH_01919 2.9e-156 tatD L hydrolase, TatD family
PCDPMHHH_01920 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PCDPMHHH_01921 4e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PCDPMHHH_01922 6.8e-37 veg S Biofilm formation stimulator VEG
PCDPMHHH_01923 9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PCDPMHHH_01924 7.4e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
PCDPMHHH_01925 1.7e-122 fhuC P ABC transporter
PCDPMHHH_01926 8e-127 znuB U ABC 3 transport family
PCDPMHHH_01927 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PCDPMHHH_01928 3.7e-241 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PCDPMHHH_01929 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCDPMHHH_01930 5.6e-50
PCDPMHHH_01931 5.1e-203 rarA L recombination factor protein RarA
PCDPMHHH_01932 1.1e-147 yxeH S hydrolase
PCDPMHHH_01933 3.8e-270 ywfO S HD domain protein
PCDPMHHH_01934 1.2e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
PCDPMHHH_01935 1.2e-67 ywiB S Domain of unknown function (DUF1934)
PCDPMHHH_01936 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PCDPMHHH_01937 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PCDPMHHH_01938 5.2e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PCDPMHHH_01939 4.6e-41 rpmE2 J Ribosomal protein L31
PCDPMHHH_01940 4.8e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PCDPMHHH_01941 6.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
PCDPMHHH_01942 6.6e-125 srtA 3.4.22.70 M sortase family
PCDPMHHH_01943 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PCDPMHHH_01944 2.1e-159 3.2.1.55 GH51 G Right handed beta helix region
PCDPMHHH_01945 2.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PCDPMHHH_01946 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PCDPMHHH_01947 2.7e-120 pgm3 G Belongs to the phosphoglycerate mutase family
PCDPMHHH_01948 6.8e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PCDPMHHH_01949 7e-93 lemA S LemA family
PCDPMHHH_01950 1.5e-158 htpX O Belongs to the peptidase M48B family
PCDPMHHH_01951 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PCDPMHHH_01952 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PCDPMHHH_01953 0.0 sprD D Domain of Unknown Function (DUF1542)
PCDPMHHH_01954 2e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
PCDPMHHH_01955 1.2e-254 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PCDPMHHH_01956 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PCDPMHHH_01957 2.3e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
PCDPMHHH_01958 7.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PCDPMHHH_01960 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PCDPMHHH_01961 3.9e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PCDPMHHH_01962 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
PCDPMHHH_01963 1.2e-250 U Belongs to the purine-cytosine permease (2.A.39) family
PCDPMHHH_01964 8.1e-243 codA 3.5.4.1 F cytosine deaminase
PCDPMHHH_01965 3.1e-147 tesE Q hydratase
PCDPMHHH_01966 1.8e-113 S (CBS) domain
PCDPMHHH_01967 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PCDPMHHH_01968 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PCDPMHHH_01969 2.3e-38 yabO J S4 domain protein
PCDPMHHH_01970 5.6e-56 divIC D Septum formation initiator
PCDPMHHH_01971 9.8e-67 yabR J RNA binding
PCDPMHHH_01972 1.9e-264 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PCDPMHHH_01973 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PCDPMHHH_01974 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCDPMHHH_01975 3.6e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PCDPMHHH_01976 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCDPMHHH_01977 1e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PCDPMHHH_01978 8.6e-85
PCDPMHHH_01991 4.2e-21 L hmm pf00665
PCDPMHHH_01992 9.2e-176 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PCDPMHHH_01993 2.2e-159 rrmA 2.1.1.187 H Methyltransferase
PCDPMHHH_01994 1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PCDPMHHH_01995 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PCDPMHHH_01996 1.2e-10 S Protein of unknown function (DUF4044)
PCDPMHHH_01997 1.7e-57
PCDPMHHH_01998 3.1e-77 mraZ K Belongs to the MraZ family
PCDPMHHH_01999 2.7e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PCDPMHHH_02000 1.5e-56 ftsL D Cell division protein FtsL
PCDPMHHH_02001 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PCDPMHHH_02002 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PCDPMHHH_02003 1.7e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PCDPMHHH_02004 7.8e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PCDPMHHH_02005 1.6e-149 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PCDPMHHH_02006 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PCDPMHHH_02007 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PCDPMHHH_02008 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PCDPMHHH_02009 3.2e-40 yggT S YGGT family
PCDPMHHH_02010 1.9e-144 ylmH S S4 domain protein
PCDPMHHH_02011 1.9e-42 divIVA D DivIVA domain protein
PCDPMHHH_02012 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PCDPMHHH_02013 1.6e-31 cspA K Cold shock protein
PCDPMHHH_02014 2e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PCDPMHHH_02016 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PCDPMHHH_02017 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
PCDPMHHH_02018 7.5e-58 XK27_04120 S Putative amino acid metabolism
PCDPMHHH_02019 1.5e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PCDPMHHH_02020 8.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PCDPMHHH_02021 9e-119 S Repeat protein
PCDPMHHH_02022 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PCDPMHHH_02023 5.3e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCDPMHHH_02030 1e-131 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PCDPMHHH_02031 2.4e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PCDPMHHH_02032 7.2e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PCDPMHHH_02033 2.3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PCDPMHHH_02034 1.1e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PCDPMHHH_02035 1.2e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PCDPMHHH_02036 2.9e-224 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PCDPMHHH_02037 8.7e-128 IQ reductase
PCDPMHHH_02038 1.5e-159 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PCDPMHHH_02039 1.5e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCDPMHHH_02040 7.1e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PCDPMHHH_02041 1.2e-76 marR K Transcriptional regulator, MarR family
PCDPMHHH_02042 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PCDPMHHH_02044 4.6e-202 xerS L Belongs to the 'phage' integrase family
PCDPMHHH_02045 5.5e-158 rssA S Phospholipase, patatin family
PCDPMHHH_02046 2.5e-118 L Integrase
PCDPMHHH_02047 3.2e-153 EG EamA-like transporter family
PCDPMHHH_02048 3.3e-129 narI 1.7.5.1 C Nitrate reductase
PCDPMHHH_02049 7.4e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
PCDPMHHH_02050 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
PCDPMHHH_02051 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PCDPMHHH_02052 3.4e-183 moeB 2.7.7.73, 2.7.7.80 H ThiF family
PCDPMHHH_02053 3.7e-82 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PCDPMHHH_02054 5.3e-223 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
PCDPMHHH_02055 1.4e-73 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PCDPMHHH_02056 6.4e-94 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PCDPMHHH_02057 6.7e-44
PCDPMHHH_02058 1e-182 comP 2.7.13.3 F Sensor histidine kinase
PCDPMHHH_02059 4.9e-114 nreC K PFAM regulatory protein LuxR
PCDPMHHH_02060 9.4e-19
PCDPMHHH_02061 2e-172
PCDPMHHH_02062 2.6e-142 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
PCDPMHHH_02063 3.9e-218 narK P Transporter, major facilitator family protein
PCDPMHHH_02064 3.9e-32 moaD 2.8.1.12 H ThiS family
PCDPMHHH_02065 2.4e-63 moaE 2.8.1.12 H MoaE protein
PCDPMHHH_02066 1.1e-75 S Flavodoxin
PCDPMHHH_02067 2e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCDPMHHH_02068 2.7e-127 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
PCDPMHHH_02069 1.2e-175 fecB P Periplasmic binding protein
PCDPMHHH_02070 5.4e-178
PCDPMHHH_02071 1.2e-73
PCDPMHHH_02072 7.6e-115 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
PCDPMHHH_02073 0.0 S SEC-C Motif Domain Protein
PCDPMHHH_02074 1.2e-51
PCDPMHHH_02075 4.6e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PCDPMHHH_02076 2.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PCDPMHHH_02077 8.1e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)