ORF_ID e_value Gene_name EC_number CAZy COGs Description
MDBPHIKD_00001 1.7e-156 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MDBPHIKD_00002 2.4e-272 ywfO S HD domain protein
MDBPHIKD_00003 4.1e-150 yxeH S hydrolase
MDBPHIKD_00004 5.6e-50
MDBPHIKD_00005 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDBPHIKD_00006 1.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDBPHIKD_00007 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MDBPHIKD_00008 3.2e-128 znuB U ABC 3 transport family
MDBPHIKD_00009 7.7e-123 fhuC P ABC transporter
MDBPHIKD_00010 1.3e-170 znuA P Belongs to the bacterial solute-binding protein 9 family
MDBPHIKD_00011 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDBPHIKD_00012 6.8e-37 veg S Biofilm formation stimulator VEG
MDBPHIKD_00013 3.8e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDBPHIKD_00014 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDBPHIKD_00015 1.5e-157 tatD L hydrolase, TatD family
MDBPHIKD_00016 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDBPHIKD_00017 7.4e-163 yunF F Protein of unknown function DUF72
MDBPHIKD_00019 4.2e-132 cobB K SIR2 family
MDBPHIKD_00020 1.1e-178
MDBPHIKD_00021 1.3e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MDBPHIKD_00022 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MDBPHIKD_00023 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDBPHIKD_00024 1.3e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MDBPHIKD_00025 1.7e-81 ndk 2.7.4.6 F Belongs to the NDK family
MDBPHIKD_00026 0.0 helD 3.6.4.12 L DNA helicase
MDBPHIKD_00027 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDBPHIKD_00029 6.3e-257 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDBPHIKD_00030 1.2e-266 yfnA E amino acid
MDBPHIKD_00031 4.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDBPHIKD_00032 8.6e-44 1.3.5.4 S FMN binding
MDBPHIKD_00033 1.7e-221 norA EGP Major facilitator Superfamily
MDBPHIKD_00034 3.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MDBPHIKD_00035 3.9e-156 metQ1 P Belongs to the nlpA lipoprotein family
MDBPHIKD_00036 1.5e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDBPHIKD_00037 3.1e-103 metI P ABC transporter permease
MDBPHIKD_00038 4.4e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MDBPHIKD_00039 4.9e-254 clcA P chloride
MDBPHIKD_00040 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MDBPHIKD_00041 5.8e-104 proW P ABC transporter, permease protein
MDBPHIKD_00042 1.3e-142 proV E ABC transporter, ATP-binding protein
MDBPHIKD_00043 9.7e-110 proWZ P ABC transporter permease
MDBPHIKD_00044 7e-164 proX M ABC transporter, substrate-binding protein, QAT family
MDBPHIKD_00045 2e-74 K Transcriptional regulator
MDBPHIKD_00046 3.8e-159 1.6.5.2 GM NAD(P)H-binding
MDBPHIKD_00048 3.1e-228 5.4.2.7 G Metalloenzyme superfamily
MDBPHIKD_00049 0.0 cadA P P-type ATPase
MDBPHIKD_00050 6.4e-131 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MDBPHIKD_00051 4.4e-129
MDBPHIKD_00052 3.3e-55 S Sugar efflux transporter for intercellular exchange
MDBPHIKD_00053 1.8e-256 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MDBPHIKD_00055 0.0 L Helicase C-terminal domain protein
MDBPHIKD_00056 1.5e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
MDBPHIKD_00057 2.1e-182 S Aldo keto reductase
MDBPHIKD_00059 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDBPHIKD_00060 2e-62 psiE S Phosphate-starvation-inducible E
MDBPHIKD_00061 5.5e-103 ydeN S Serine hydrolase
MDBPHIKD_00063 1.9e-50 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDBPHIKD_00064 1.7e-108 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDBPHIKD_00065 2.3e-257 nhaC C Na H antiporter NhaC
MDBPHIKD_00066 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
MDBPHIKD_00067 5.7e-115 ywnB S NAD(P)H-binding
MDBPHIKD_00068 4.4e-38
MDBPHIKD_00069 2.6e-132 IQ Dehydrogenase reductase
MDBPHIKD_00070 3.3e-242 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
MDBPHIKD_00071 5.6e-39 hxlR K regulation of RNA biosynthetic process
MDBPHIKD_00072 7.9e-168 G Belongs to the carbohydrate kinase PfkB family
MDBPHIKD_00073 1.8e-256 F Belongs to the purine-cytosine permease (2.A.39) family
MDBPHIKD_00074 1.1e-208 yegU O ADP-ribosylglycohydrolase
MDBPHIKD_00075 2.7e-105 pncA Q Isochorismatase family
MDBPHIKD_00076 2.7e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDBPHIKD_00077 1.9e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
MDBPHIKD_00078 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MDBPHIKD_00079 1.3e-218 yfeO P Voltage gated chloride channel
MDBPHIKD_00080 2.4e-226 sptS 2.7.13.3 T Histidine kinase
MDBPHIKD_00081 1.9e-118 K response regulator
MDBPHIKD_00082 8.2e-87 2.7.6.5 T Region found in RelA / SpoT proteins
MDBPHIKD_00083 3e-72
MDBPHIKD_00084 1.9e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MDBPHIKD_00085 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MDBPHIKD_00086 8.1e-257 malT G Major Facilitator
MDBPHIKD_00087 2.1e-216 phbA 2.3.1.9 I Belongs to the thiolase family
MDBPHIKD_00088 7.1e-175 malR K Transcriptional regulator, LacI family
MDBPHIKD_00089 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MDBPHIKD_00090 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDBPHIKD_00091 2.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDBPHIKD_00092 2.3e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
MDBPHIKD_00094 0.0 clpL O associated with various cellular activities
MDBPHIKD_00095 2.7e-32
MDBPHIKD_00096 1.5e-222 patA 2.6.1.1 E Aminotransferase
MDBPHIKD_00097 3.2e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDBPHIKD_00098 5e-75 osmC O OsmC-like protein
MDBPHIKD_00099 1.3e-28 2.7.13.3 T GHKL domain
MDBPHIKD_00102 2.5e-269 S Putative peptidoglycan binding domain
MDBPHIKD_00103 2.5e-20
MDBPHIKD_00105 2.8e-219 bacI V MacB-like periplasmic core domain
MDBPHIKD_00106 2e-129 V ABC transporter
MDBPHIKD_00107 1.4e-145 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MDBPHIKD_00108 2.1e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MDBPHIKD_00109 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDBPHIKD_00110 6.5e-150 E Glyoxalase-like domain
MDBPHIKD_00111 7.5e-155 glcU U sugar transport
MDBPHIKD_00112 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
MDBPHIKD_00113 2.9e-96 S reductase
MDBPHIKD_00115 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDBPHIKD_00116 4.1e-181 ABC-SBP S ABC transporter
MDBPHIKD_00117 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MDBPHIKD_00118 6.4e-219 htrA 3.4.21.107 O serine protease
MDBPHIKD_00119 1.2e-154 vicX 3.1.26.11 S domain protein
MDBPHIKD_00120 2.6e-152 yycI S YycH protein
MDBPHIKD_00121 4.9e-251 yycH S YycH protein
MDBPHIKD_00122 0.0 vicK 2.7.13.3 T Histidine kinase
MDBPHIKD_00123 3.1e-130 K response regulator
MDBPHIKD_00125 0.0 lmrA 3.6.3.44 V ABC transporter
MDBPHIKD_00126 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
MDBPHIKD_00128 3.1e-101 K DNA-binding helix-turn-helix protein
MDBPHIKD_00129 2.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
MDBPHIKD_00130 1.5e-60
MDBPHIKD_00131 6.9e-207 yttB EGP Major facilitator Superfamily
MDBPHIKD_00132 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MDBPHIKD_00133 2e-74 rplI J Binds to the 23S rRNA
MDBPHIKD_00134 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MDBPHIKD_00135 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDBPHIKD_00136 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDBPHIKD_00137 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MDBPHIKD_00138 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDBPHIKD_00139 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDBPHIKD_00140 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDBPHIKD_00141 1.7e-34 yaaA S S4 domain protein YaaA
MDBPHIKD_00142 2.9e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDBPHIKD_00143 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDBPHIKD_00144 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MDBPHIKD_00145 1.2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDBPHIKD_00146 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDBPHIKD_00147 4.1e-136 jag S R3H domain protein
MDBPHIKD_00148 5e-84
MDBPHIKD_00149 2.2e-190 lacR K Transcriptional regulator
MDBPHIKD_00150 0.0 lacS G Transporter
MDBPHIKD_00151 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MDBPHIKD_00152 1.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDBPHIKD_00153 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MDBPHIKD_00154 1.3e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
MDBPHIKD_00155 7.7e-224 yxjG_1 E methionine synthase, vitamin-B12 independent
MDBPHIKD_00156 2.8e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDBPHIKD_00157 8.2e-224 mdtG EGP Major facilitator Superfamily
MDBPHIKD_00158 1.2e-168 T Calcineurin-like phosphoesterase superfamily domain
MDBPHIKD_00159 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDBPHIKD_00162 1.2e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MDBPHIKD_00163 3e-143 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MDBPHIKD_00164 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
MDBPHIKD_00165 0.0 trxB2 1.8.1.9 C Thioredoxin domain
MDBPHIKD_00166 3.7e-162 L hmm pf00665
MDBPHIKD_00167 5.1e-57 L Helix-turn-helix domain
MDBPHIKD_00168 2e-32 L Helix-turn-helix domain
MDBPHIKD_00169 2.5e-155 KT YcbB domain
MDBPHIKD_00170 2.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDBPHIKD_00171 1.5e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
MDBPHIKD_00172 3.2e-164 EG EamA-like transporter family
MDBPHIKD_00173 2e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MDBPHIKD_00174 7.6e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDBPHIKD_00175 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDBPHIKD_00176 0.0 copA 3.6.3.54 P P-type ATPase
MDBPHIKD_00177 1.6e-90
MDBPHIKD_00179 3.6e-57
MDBPHIKD_00180 8.6e-241 yjcE P Sodium proton antiporter
MDBPHIKD_00184 2.1e-66
MDBPHIKD_00186 4.8e-72
MDBPHIKD_00188 5.3e-08 L DnaD domain protein
MDBPHIKD_00191 2.1e-79 L hmm pf00665
MDBPHIKD_00192 5.8e-106 L Helix-turn-helix domain
MDBPHIKD_00193 5.5e-267 aaxC E Arginine ornithine antiporter
MDBPHIKD_00194 1.7e-184 4.1.1.22 H Histidine carboxylase PI chain
MDBPHIKD_00195 2.5e-97 S Family of unknown function (DUF5449)
MDBPHIKD_00196 7.1e-250 hisS 6.1.1.21 J histidyl-tRNA synthetase
MDBPHIKD_00197 1.9e-248 nhaC C Na H antiporter NhaC
MDBPHIKD_00198 1.9e-242 pbuX F xanthine permease
MDBPHIKD_00199 2.6e-285 pipD E Dipeptidase
MDBPHIKD_00200 9.7e-169 corA P CorA-like Mg2+ transporter protein
MDBPHIKD_00201 7.4e-177 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDBPHIKD_00202 2.3e-131 terC P membrane
MDBPHIKD_00203 1.5e-55 trxA O Belongs to the thioredoxin family
MDBPHIKD_00204 1e-240 mepA V MATE efflux family protein
MDBPHIKD_00205 5.2e-56 K Transcriptional regulator, ArsR family
MDBPHIKD_00206 5.1e-96 P Cadmium resistance transporter
MDBPHIKD_00207 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
MDBPHIKD_00208 8.6e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MDBPHIKD_00209 9.8e-183 ABC-SBP S ABC transporter
MDBPHIKD_00210 1e-78 M PFAM NLP P60 protein
MDBPHIKD_00212 7.8e-14 relB L RelB antitoxin
MDBPHIKD_00213 1e-108 S Protein of unknown function (DUF3278)
MDBPHIKD_00215 2.9e-11
MDBPHIKD_00216 4.4e-275 S ABC transporter, ATP-binding protein
MDBPHIKD_00217 1.8e-147 S Putative ABC-transporter type IV
MDBPHIKD_00218 2e-106 NU mannosyl-glycoprotein
MDBPHIKD_00219 9.9e-250 brnQ U Component of the transport system for branched-chain amino acids
MDBPHIKD_00220 2.9e-232 S Uncharacterized protein conserved in bacteria (DUF2325)
MDBPHIKD_00221 1.4e-206 nrnB S DHHA1 domain
MDBPHIKD_00222 1.1e-49
MDBPHIKD_00223 2.4e-141 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDBPHIKD_00224 3.3e-18 S Domain of unknown function (DUF4767)
MDBPHIKD_00225 1.6e-54
MDBPHIKD_00226 6e-123 yrkL S Flavodoxin-like fold
MDBPHIKD_00228 1.4e-65 yeaO S Protein of unknown function, DUF488
MDBPHIKD_00229 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MDBPHIKD_00230 1.4e-209 3.1.3.1 S associated with various cellular activities
MDBPHIKD_00231 5.6e-247 S Putative metallopeptidase domain
MDBPHIKD_00232 3.6e-48
MDBPHIKD_00233 0.0 pepO 3.4.24.71 O Peptidase family M13
MDBPHIKD_00234 3.9e-113 K Helix-turn-helix XRE-family like proteins
MDBPHIKD_00235 1.5e-91 ymdB S Macro domain protein
MDBPHIKD_00236 3.9e-199 EGP Major facilitator Superfamily
MDBPHIKD_00237 2.2e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDBPHIKD_00238 1.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MDBPHIKD_00239 7.4e-160 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MDBPHIKD_00240 0.0 ysaB V FtsX-like permease family
MDBPHIKD_00241 6.8e-136 macB2 V ABC transporter, ATP-binding protein
MDBPHIKD_00242 8.7e-184 T Histidine kinase-like ATPases
MDBPHIKD_00243 3.4e-126 K response regulator
MDBPHIKD_00244 9.9e-160 ytbE 1.1.1.346 S Aldo keto reductase
MDBPHIKD_00245 1.8e-136 pnuC H nicotinamide mononucleotide transporter
MDBPHIKD_00246 1.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDBPHIKD_00247 4.6e-205
MDBPHIKD_00248 9.1e-53
MDBPHIKD_00249 9.1e-36
MDBPHIKD_00250 4.3e-94 yxkA S Phosphatidylethanolamine-binding protein
MDBPHIKD_00251 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
MDBPHIKD_00252 2.2e-187 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
MDBPHIKD_00253 1.2e-227 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDBPHIKD_00254 1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MDBPHIKD_00255 3.7e-182 galR K Transcriptional regulator
MDBPHIKD_00256 2.8e-108 tra L Transposase and inactivated derivatives, IS30 family
MDBPHIKD_00257 9.8e-82 L transposase and inactivated derivatives, IS30 family
MDBPHIKD_00258 1.7e-103 dedA 3.1.3.1 S SNARE associated Golgi protein
MDBPHIKD_00259 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDBPHIKD_00260 1.5e-80 K AsnC family
MDBPHIKD_00261 1.5e-80 uspA T universal stress protein
MDBPHIKD_00262 0.0 lacS G Transporter
MDBPHIKD_00263 1.1e-40
MDBPHIKD_00264 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDBPHIKD_00265 5.7e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDBPHIKD_00266 3.6e-194 yeaN P Transporter, major facilitator family protein
MDBPHIKD_00267 1.4e-74 S 3-demethylubiquinone-9 3-methyltransferase
MDBPHIKD_00268 9.9e-85 nrdI F Belongs to the NrdI family
MDBPHIKD_00269 1.1e-242 yhdP S Transporter associated domain
MDBPHIKD_00270 4.7e-157 ypdB V (ABC) transporter
MDBPHIKD_00271 7.2e-92 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
MDBPHIKD_00272 6.1e-91 M1-874 K Domain of unknown function (DUF1836)
MDBPHIKD_00273 1.7e-78 yybA 2.3.1.57 K Transcriptional regulator
MDBPHIKD_00274 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
MDBPHIKD_00275 1.8e-177 S AI-2E family transporter
MDBPHIKD_00276 3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MDBPHIKD_00277 9e-167
MDBPHIKD_00278 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MDBPHIKD_00279 4.1e-150 eutJ E Hsp70 protein
MDBPHIKD_00280 3e-201 K helix_turn_helix, arabinose operon control protein
MDBPHIKD_00281 6.2e-42 pduA_4 CQ BMC
MDBPHIKD_00282 2.7e-134 pduB E BMC
MDBPHIKD_00283 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
MDBPHIKD_00284 3.8e-128 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
MDBPHIKD_00285 2.1e-80 pduE 4.2.1.28 Q Dehydratase small subunit
MDBPHIKD_00286 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
MDBPHIKD_00287 1.7e-60 pduH S Dehydratase medium subunit
MDBPHIKD_00288 5.1e-75 pduK CQ BMC
MDBPHIKD_00289 7.6e-43 pduA_4 CQ BMC
MDBPHIKD_00290 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
MDBPHIKD_00291 6.4e-90 S Putative propanediol utilisation
MDBPHIKD_00292 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
MDBPHIKD_00293 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
MDBPHIKD_00294 7.4e-80 pduO S Haem-degrading
MDBPHIKD_00295 3.1e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
MDBPHIKD_00296 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
MDBPHIKD_00297 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDBPHIKD_00298 5.5e-56 pduU E BMC
MDBPHIKD_00299 1.9e-149 3.1.3.48 T Pfam:Y_phosphatase3C
MDBPHIKD_00300 3.1e-121 pgm1 3.1.3.73 G phosphoglycerate mutase
MDBPHIKD_00301 3.1e-93 P Cadmium resistance transporter
MDBPHIKD_00302 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
MDBPHIKD_00303 1e-78 fld C Flavodoxin
MDBPHIKD_00304 7.1e-158 XK27_04590 S NADPH-dependent FMN reductase
MDBPHIKD_00305 1.7e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
MDBPHIKD_00306 1.2e-208 cobD 4.1.1.81 E Aminotransferase class I and II
MDBPHIKD_00307 4.1e-264 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
MDBPHIKD_00308 2.2e-179 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MDBPHIKD_00309 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
MDBPHIKD_00310 1.6e-208 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
MDBPHIKD_00311 1e-110 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MDBPHIKD_00312 5.4e-98 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
MDBPHIKD_00313 4.8e-137 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MDBPHIKD_00314 8.2e-196 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
MDBPHIKD_00315 5.7e-132 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MDBPHIKD_00316 2.5e-138 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
MDBPHIKD_00317 3e-262 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MDBPHIKD_00318 2.3e-147 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
MDBPHIKD_00319 5.1e-125 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MDBPHIKD_00320 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
MDBPHIKD_00321 8.7e-53 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
MDBPHIKD_00322 4.4e-118 cbiQ P Cobalt transport protein
MDBPHIKD_00323 2e-149 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
MDBPHIKD_00324 3.3e-283 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
MDBPHIKD_00325 3.2e-80 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
MDBPHIKD_00326 1.4e-237 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MDBPHIKD_00327 2.3e-170 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MDBPHIKD_00328 2.4e-181 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
MDBPHIKD_00329 3.4e-252 hemL 5.4.3.8 H Aminotransferase class-III
MDBPHIKD_00330 1.6e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
MDBPHIKD_00331 4.8e-137 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MDBPHIKD_00332 5.4e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
MDBPHIKD_00333 7.3e-132 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MDBPHIKD_00334 5.9e-194 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
MDBPHIKD_00335 2.5e-62 S Domain of unknown function (DUF4430)
MDBPHIKD_00336 1.2e-81 S ECF transporter, substrate-specific component
MDBPHIKD_00337 2.9e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDBPHIKD_00338 4.8e-310 lmrA V ABC transporter, ATP-binding protein
MDBPHIKD_00339 2.1e-310 yfiC V ABC transporter
MDBPHIKD_00340 1.2e-285 pipD E Dipeptidase
MDBPHIKD_00341 4.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDBPHIKD_00342 4.3e-135 gntR K UbiC transcription regulator-associated domain protein
MDBPHIKD_00343 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MDBPHIKD_00344 7.2e-245 yagE E amino acid
MDBPHIKD_00345 7e-141 aroD S Serine hydrolase (FSH1)
MDBPHIKD_00346 4.9e-240 L transposase, IS605 OrfB family
MDBPHIKD_00347 1.3e-81 tlpA2 L Transposase IS200 like
MDBPHIKD_00348 7.2e-245 brnQ U Component of the transport system for branched-chain amino acids
MDBPHIKD_00349 2.1e-168 GK ROK family
MDBPHIKD_00350 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDBPHIKD_00351 6.7e-164 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDBPHIKD_00352 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MDBPHIKD_00353 1.1e-141 S Belongs to the UPF0246 family
MDBPHIKD_00354 2.5e-138 S Membrane
MDBPHIKD_00355 8.1e-75 4.4.1.5 E Glyoxalase
MDBPHIKD_00356 1e-20
MDBPHIKD_00357 1.7e-87 yueI S Protein of unknown function (DUF1694)
MDBPHIKD_00358 3.4e-244 rarA L recombination factor protein RarA
MDBPHIKD_00359 4.4e-46
MDBPHIKD_00360 4.3e-83 usp6 T universal stress protein
MDBPHIKD_00361 1.5e-208 araR K Transcriptional regulator
MDBPHIKD_00362 2.2e-159 ytbE 1.1.1.346 S Aldo keto reductase
MDBPHIKD_00363 2e-100 maa 2.3.1.79 S Maltose O-acetyltransferase
MDBPHIKD_00364 8.8e-286 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MDBPHIKD_00365 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MDBPHIKD_00366 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
MDBPHIKD_00367 5.2e-262 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDBPHIKD_00368 1.6e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MDBPHIKD_00369 6.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MDBPHIKD_00370 2.9e-154 EG EamA-like transporter family
MDBPHIKD_00371 2.5e-118 L Integrase
MDBPHIKD_00372 1.7e-159 rssA S Phospholipase, patatin family
MDBPHIKD_00373 1.2e-213 L PFAM Integrase catalytic region
MDBPHIKD_00374 1.5e-32 L PFAM Integrase catalytic region
MDBPHIKD_00376 2.8e-19
MDBPHIKD_00377 1.3e-263 dtpT U amino acid peptide transporter
MDBPHIKD_00378 5.2e-161 yjjH S Calcineurin-like phosphoesterase
MDBPHIKD_00381 1.5e-115
MDBPHIKD_00382 9.7e-253 EGP Major facilitator Superfamily
MDBPHIKD_00383 2.9e-304 aspT P Predicted Permease Membrane Region
MDBPHIKD_00384 2.5e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MDBPHIKD_00385 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
MDBPHIKD_00386 1.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDBPHIKD_00387 3.9e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDBPHIKD_00388 0.0 yhgF K Tex-like protein N-terminal domain protein
MDBPHIKD_00389 8.6e-86 ydcK S Belongs to the SprT family
MDBPHIKD_00391 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MDBPHIKD_00392 7.5e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MDBPHIKD_00393 0.0 S Bacterial membrane protein, YfhO
MDBPHIKD_00394 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDBPHIKD_00395 6.3e-170 I alpha/beta hydrolase fold
MDBPHIKD_00396 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MDBPHIKD_00397 1.1e-119 tcyB E ABC transporter
MDBPHIKD_00398 2.6e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDBPHIKD_00399 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MDBPHIKD_00400 5.4e-269 pepC 3.4.22.40 E Peptidase C1-like family
MDBPHIKD_00401 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDBPHIKD_00402 8.5e-50 HA62_12640 S GCN5-related N-acetyl-transferase
MDBPHIKD_00403 2.3e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MDBPHIKD_00404 3.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDBPHIKD_00405 1e-207 yacL S domain protein
MDBPHIKD_00406 2.6e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDBPHIKD_00407 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDBPHIKD_00408 1.8e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDBPHIKD_00409 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDBPHIKD_00410 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDBPHIKD_00411 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
MDBPHIKD_00412 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDBPHIKD_00413 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDBPHIKD_00414 7e-228 aadAT EK Aminotransferase, class I
MDBPHIKD_00416 2.1e-249 M Glycosyl transferase family group 2
MDBPHIKD_00417 3e-212 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDBPHIKD_00418 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDBPHIKD_00419 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDBPHIKD_00420 3.4e-48
MDBPHIKD_00422 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDBPHIKD_00423 1.1e-56 K transcriptional regulator PadR family
MDBPHIKD_00424 6.2e-79 XK27_06920 S Protein of unknown function (DUF1700)
MDBPHIKD_00425 3.1e-136 S Putative adhesin
MDBPHIKD_00426 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MDBPHIKD_00427 1.2e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDBPHIKD_00428 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDBPHIKD_00429 3.4e-35 nrdH O Glutaredoxin
MDBPHIKD_00430 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDBPHIKD_00431 7.3e-309 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDBPHIKD_00432 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDBPHIKD_00433 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDBPHIKD_00434 9.7e-39 S Protein of unknown function (DUF2508)
MDBPHIKD_00435 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDBPHIKD_00436 7.6e-52 yaaQ S Cyclic-di-AMP receptor
MDBPHIKD_00437 1.5e-186 holB 2.7.7.7 L DNA polymerase III
MDBPHIKD_00438 1.6e-58 yabA L Involved in initiation control of chromosome replication
MDBPHIKD_00439 1.5e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDBPHIKD_00440 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
MDBPHIKD_00441 2.7e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MDBPHIKD_00442 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MDBPHIKD_00443 6.6e-176 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MDBPHIKD_00444 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDBPHIKD_00445 1.2e-213 L PFAM Integrase catalytic region
MDBPHIKD_00446 1.5e-32 L PFAM Integrase catalytic region
MDBPHIKD_00447 1e-47 gcvH E glycine cleavage
MDBPHIKD_00448 1.1e-220 rodA D Belongs to the SEDS family
MDBPHIKD_00449 2.7e-32 S Protein of unknown function (DUF2969)
MDBPHIKD_00450 1.9e-178 mbl D Cell shape determining protein MreB Mrl
MDBPHIKD_00451 6.5e-243 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDBPHIKD_00452 1.3e-33 ywzB S Protein of unknown function (DUF1146)
MDBPHIKD_00453 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MDBPHIKD_00454 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDBPHIKD_00455 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDBPHIKD_00456 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDBPHIKD_00457 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDBPHIKD_00458 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDBPHIKD_00459 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDBPHIKD_00460 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
MDBPHIKD_00461 5.9e-233 pyrP F Permease
MDBPHIKD_00462 1.8e-131 yibF S overlaps another CDS with the same product name
MDBPHIKD_00463 3.3e-195 yibE S overlaps another CDS with the same product name
MDBPHIKD_00464 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDBPHIKD_00465 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDBPHIKD_00466 9.8e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDBPHIKD_00467 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDBPHIKD_00468 1.4e-169 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDBPHIKD_00469 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDBPHIKD_00470 6e-108 tdk 2.7.1.21 F thymidine kinase
MDBPHIKD_00471 8.9e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
MDBPHIKD_00472 1.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MDBPHIKD_00473 1.6e-226 arcD U Amino acid permease
MDBPHIKD_00474 6.8e-262 E Arginine ornithine antiporter
MDBPHIKD_00475 1.2e-79 argR K Regulates arginine biosynthesis genes
MDBPHIKD_00476 4.1e-239 arcA 3.5.3.6 E Arginine
MDBPHIKD_00477 1.1e-197 ampC V Beta-lactamase
MDBPHIKD_00478 4.5e-26
MDBPHIKD_00479 5.8e-106 L Helix-turn-helix domain
MDBPHIKD_00480 2.1e-79 L hmm pf00665
MDBPHIKD_00481 1.7e-23
MDBPHIKD_00482 2.8e-185
MDBPHIKD_00483 8.4e-31
MDBPHIKD_00484 1.5e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MDBPHIKD_00485 2.2e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDBPHIKD_00486 7.5e-103 fic D Fic/DOC family
MDBPHIKD_00487 5.1e-69
MDBPHIKD_00488 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
MDBPHIKD_00489 8.4e-93 L nuclease
MDBPHIKD_00490 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MDBPHIKD_00491 3e-212 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MDBPHIKD_00492 1.7e-145 ywqE 3.1.3.48 GM PHP domain protein
MDBPHIKD_00493 6.7e-159 snf 2.7.11.1 KL domain protein
MDBPHIKD_00494 0.0 snf 2.7.11.1 KL domain protein
MDBPHIKD_00496 9.6e-149 S Protein of unknown function (DUF3800)
MDBPHIKD_00497 3.2e-11 K transcriptional regulator
MDBPHIKD_00499 4.8e-252 mmuP E amino acid
MDBPHIKD_00500 1.9e-175 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MDBPHIKD_00501 1.3e-70 O Preprotein translocase subunit SecB
MDBPHIKD_00502 6.8e-262 yfnA E amino acid
MDBPHIKD_00503 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MDBPHIKD_00504 3.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDBPHIKD_00505 4.1e-40 ylqC S Belongs to the UPF0109 family
MDBPHIKD_00506 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MDBPHIKD_00507 2.7e-250 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDBPHIKD_00508 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDBPHIKD_00509 2.2e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDBPHIKD_00510 0.0 smc D Required for chromosome condensation and partitioning
MDBPHIKD_00511 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDBPHIKD_00512 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDBPHIKD_00513 7.3e-189 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDBPHIKD_00514 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDBPHIKD_00515 0.0 yloV S DAK2 domain fusion protein YloV
MDBPHIKD_00516 4.7e-58 asp S Asp23 family, cell envelope-related function
MDBPHIKD_00517 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MDBPHIKD_00518 7.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
MDBPHIKD_00519 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MDBPHIKD_00520 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDBPHIKD_00521 0.0 KLT serine threonine protein kinase
MDBPHIKD_00522 6.9e-133 stp 3.1.3.16 T phosphatase
MDBPHIKD_00523 2e-255 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDBPHIKD_00524 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDBPHIKD_00525 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDBPHIKD_00526 5.1e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDBPHIKD_00527 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDBPHIKD_00528 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MDBPHIKD_00529 1.7e-54
MDBPHIKD_00530 2.3e-264 recN L May be involved in recombinational repair of damaged DNA
MDBPHIKD_00531 1e-78 argR K Regulates arginine biosynthesis genes
MDBPHIKD_00532 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MDBPHIKD_00533 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDBPHIKD_00534 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDBPHIKD_00535 6.7e-203 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDBPHIKD_00536 3.4e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDBPHIKD_00537 3.6e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDBPHIKD_00538 2.2e-70 yqhY S Asp23 family, cell envelope-related function
MDBPHIKD_00539 4.5e-123 J 2'-5' RNA ligase superfamily
MDBPHIKD_00540 1.7e-204 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDBPHIKD_00541 8.6e-133 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MDBPHIKD_00542 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MDBPHIKD_00543 7.4e-55 ysxB J Cysteine protease Prp
MDBPHIKD_00544 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
MDBPHIKD_00545 2.6e-112 K Transcriptional regulator
MDBPHIKD_00548 6.5e-90 dut S Protein conserved in bacteria
MDBPHIKD_00549 1.8e-187
MDBPHIKD_00550 2.7e-152
MDBPHIKD_00551 1.3e-51 S Iron-sulfur cluster assembly protein
MDBPHIKD_00552 5e-101 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDBPHIKD_00553 1.3e-156 P Belongs to the nlpA lipoprotein family
MDBPHIKD_00554 3.9e-12
MDBPHIKD_00555 1.1e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MDBPHIKD_00556 4e-297 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDBPHIKD_00557 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
MDBPHIKD_00558 1e-178 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDBPHIKD_00559 5.9e-22 S Protein of unknown function (DUF3042)
MDBPHIKD_00560 9.1e-68 yqhL P Rhodanese-like protein
MDBPHIKD_00561 1.5e-183 glk 2.7.1.2 G Glucokinase
MDBPHIKD_00562 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
MDBPHIKD_00563 2.2e-114 gluP 3.4.21.105 S Peptidase, S54 family
MDBPHIKD_00564 1.4e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDBPHIKD_00565 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDBPHIKD_00566 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MDBPHIKD_00567 0.0 S membrane
MDBPHIKD_00568 4e-71 yneR S Belongs to the HesB IscA family
MDBPHIKD_00569 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDBPHIKD_00570 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
MDBPHIKD_00571 6.9e-113 rlpA M PFAM NLP P60 protein
MDBPHIKD_00572 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDBPHIKD_00573 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDBPHIKD_00574 2.6e-58 yodB K Transcriptional regulator, HxlR family
MDBPHIKD_00575 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDBPHIKD_00576 2.2e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDBPHIKD_00577 8.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MDBPHIKD_00578 1.5e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDBPHIKD_00579 9.3e-71 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDBPHIKD_00580 7.8e-236 V MatE
MDBPHIKD_00581 1.8e-268 yjeM E Amino Acid
MDBPHIKD_00582 9.8e-280 arlS 2.7.13.3 T Histidine kinase
MDBPHIKD_00583 1.5e-121 K response regulator
MDBPHIKD_00584 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MDBPHIKD_00585 2.9e-99 yceD S Uncharacterized ACR, COG1399
MDBPHIKD_00586 2.9e-215 ylbM S Belongs to the UPF0348 family
MDBPHIKD_00587 1.4e-141 yqeM Q Methyltransferase
MDBPHIKD_00588 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDBPHIKD_00589 9.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MDBPHIKD_00590 7.9e-125 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDBPHIKD_00591 1.9e-47 yhbY J RNA-binding protein
MDBPHIKD_00592 5.6e-219 yqeH S Ribosome biogenesis GTPase YqeH
MDBPHIKD_00593 2.8e-96 yqeG S HAD phosphatase, family IIIA
MDBPHIKD_00594 4.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDBPHIKD_00595 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MDBPHIKD_00596 6.3e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDBPHIKD_00597 5.1e-173 dnaI L Primosomal protein DnaI
MDBPHIKD_00598 3.2e-208 dnaB L replication initiation and membrane attachment
MDBPHIKD_00599 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDBPHIKD_00600 9.3e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDBPHIKD_00601 8.8e-161 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDBPHIKD_00602 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDBPHIKD_00603 1.8e-119 yoaK S Protein of unknown function (DUF1275)
MDBPHIKD_00604 1.4e-119 ybhL S Belongs to the BI1 family
MDBPHIKD_00605 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MDBPHIKD_00606 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDBPHIKD_00607 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MDBPHIKD_00608 7.5e-58 ytzB S Small secreted protein
MDBPHIKD_00609 5.7e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
MDBPHIKD_00610 1.1e-186 iolS C Aldo keto reductase
MDBPHIKD_00611 3.5e-293 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MDBPHIKD_00612 1.4e-220 patA 2.6.1.1 E Aminotransferase
MDBPHIKD_00613 7.7e-208 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDBPHIKD_00614 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDBPHIKD_00615 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MDBPHIKD_00616 7e-181 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MDBPHIKD_00617 2.3e-147 recO L Involved in DNA repair and RecF pathway recombination
MDBPHIKD_00618 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDBPHIKD_00619 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MDBPHIKD_00620 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDBPHIKD_00621 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
MDBPHIKD_00622 2.4e-181 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDBPHIKD_00623 4.6e-92 bioY S BioY family
MDBPHIKD_00624 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
MDBPHIKD_00625 9.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDBPHIKD_00626 1.7e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDBPHIKD_00627 2.9e-70 yqeY S YqeY-like protein
MDBPHIKD_00628 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MDBPHIKD_00629 2.8e-266 glnPH2 P ABC transporter permease
MDBPHIKD_00630 9.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDBPHIKD_00631 8.3e-69 yqkB S Belongs to the HesB IscA family
MDBPHIKD_00632 3.8e-32
MDBPHIKD_00634 4.4e-91 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MDBPHIKD_00635 1.1e-62 asp S Asp23 family, cell envelope-related function
MDBPHIKD_00636 2.1e-25
MDBPHIKD_00637 2.9e-96
MDBPHIKD_00638 1.8e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDBPHIKD_00639 1.4e-184 K Transcriptional regulator, LacI family
MDBPHIKD_00640 1.6e-233 gntT EG Gluconate
MDBPHIKD_00641 1.2e-296 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDBPHIKD_00642 1.7e-96 K Acetyltransferase (GNAT) domain
MDBPHIKD_00643 6.5e-41
MDBPHIKD_00644 2.4e-22
MDBPHIKD_00645 0.0 nylA 3.5.1.4 J Belongs to the amidase family
MDBPHIKD_00646 2.2e-44
MDBPHIKD_00647 2.8e-58 yhaI S Protein of unknown function (DUF805)
MDBPHIKD_00648 2.1e-301 2.1.1.72 V type I restriction-modification system
MDBPHIKD_00649 8.6e-111 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MDBPHIKD_00650 1.5e-180 xerC L Belongs to the 'phage' integrase family
MDBPHIKD_00651 7.2e-79 3.1.21.3 V Type I restriction modification DNA specificity domain
MDBPHIKD_00652 1.8e-96 3.1.21.3 V Type I restriction modification DNA specificity domain
MDBPHIKD_00653 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MDBPHIKD_00654 4.3e-36 higA K addiction module antidote protein HigA
MDBPHIKD_00655 0.0 L PLD-like domain
MDBPHIKD_00657 5.1e-181 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MDBPHIKD_00658 1.8e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDBPHIKD_00659 4.5e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MDBPHIKD_00660 1.8e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MDBPHIKD_00661 4.7e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDBPHIKD_00662 3.9e-104 T Ion transport 2 domain protein
MDBPHIKD_00663 0.0 S Bacterial membrane protein YfhO
MDBPHIKD_00664 5e-202 G Transporter, major facilitator family protein
MDBPHIKD_00665 2.4e-109 yvrI K sigma factor activity
MDBPHIKD_00666 1.6e-64 ydiI Q Thioesterase superfamily
MDBPHIKD_00667 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MDBPHIKD_00668 1.6e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MDBPHIKD_00669 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MDBPHIKD_00670 1.2e-31 feoA P FeoA domain
MDBPHIKD_00671 6.5e-145 sufC O FeS assembly ATPase SufC
MDBPHIKD_00672 5.4e-242 sufD O FeS assembly protein SufD
MDBPHIKD_00673 1.6e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDBPHIKD_00674 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
MDBPHIKD_00675 4.2e-272 sufB O assembly protein SufB
MDBPHIKD_00676 2.8e-57 yitW S Iron-sulfur cluster assembly protein
MDBPHIKD_00677 1.5e-161 hipB K Helix-turn-helix
MDBPHIKD_00678 1.2e-117 nreC K PFAM regulatory protein LuxR
MDBPHIKD_00679 3.2e-39 S Cytochrome B5
MDBPHIKD_00680 2.9e-156 yitU 3.1.3.104 S hydrolase
MDBPHIKD_00681 2e-266 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MDBPHIKD_00682 3.4e-147 f42a O Band 7 protein
MDBPHIKD_00683 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
MDBPHIKD_00684 1.1e-130 lytT K response regulator receiver
MDBPHIKD_00685 1.9e-66 lrgA S LrgA family
MDBPHIKD_00686 2.6e-124 lrgB M LrgB-like family
MDBPHIKD_00687 6.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDBPHIKD_00688 4.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MDBPHIKD_00689 6.3e-193 galR K Periplasmic binding protein-like domain
MDBPHIKD_00690 0.0 rafA 3.2.1.22 G alpha-galactosidase
MDBPHIKD_00691 1.9e-186 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDBPHIKD_00692 4.3e-230 mtnE 2.6.1.83 E Aminotransferase
MDBPHIKD_00693 3.6e-148 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MDBPHIKD_00694 1.4e-139 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDBPHIKD_00695 3.5e-230 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDBPHIKD_00696 2.9e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDBPHIKD_00697 1.9e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDBPHIKD_00698 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MDBPHIKD_00699 6.3e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MDBPHIKD_00700 1.5e-32 L PFAM Integrase catalytic region
MDBPHIKD_00701 1.2e-213 L PFAM Integrase catalytic region
MDBPHIKD_00702 5.1e-57 L Helix-turn-helix domain
MDBPHIKD_00703 2e-32 L Helix-turn-helix domain
MDBPHIKD_00704 6.7e-278 pipD E Dipeptidase
MDBPHIKD_00705 0.0 yjbQ P TrkA C-terminal domain protein
MDBPHIKD_00706 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MDBPHIKD_00707 5.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDBPHIKD_00708 4e-92
MDBPHIKD_00709 1.7e-37
MDBPHIKD_00710 1.2e-105 K DNA-templated transcription, initiation
MDBPHIKD_00711 4e-28
MDBPHIKD_00712 2e-32 L Helix-turn-helix domain
MDBPHIKD_00713 5.1e-57 L Helix-turn-helix domain
MDBPHIKD_00714 2.5e-163 L hmm pf00665
MDBPHIKD_00715 3.6e-45 L PFAM Integrase catalytic region
MDBPHIKD_00716 6.7e-40 S dextransucrase activity
MDBPHIKD_00717 3.5e-282 ganB 3.2.1.89 G arabinogalactan
MDBPHIKD_00718 2.1e-171 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
MDBPHIKD_00719 1.2e-64 gntR1 K Transcriptional regulator, GntR family
MDBPHIKD_00720 7.7e-160 V ABC transporter, ATP-binding protein
MDBPHIKD_00721 2.6e-118
MDBPHIKD_00722 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MDBPHIKD_00723 1.7e-100 S Pfam:DUF3816
MDBPHIKD_00724 0.0 clpE O Belongs to the ClpA ClpB family
MDBPHIKD_00725 2.2e-27
MDBPHIKD_00726 2.7e-39 ptsH G phosphocarrier protein HPR
MDBPHIKD_00727 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDBPHIKD_00728 1.2e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MDBPHIKD_00729 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
MDBPHIKD_00730 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDBPHIKD_00731 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
MDBPHIKD_00732 3.8e-08 M domain protein
MDBPHIKD_00733 3.5e-238 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDBPHIKD_00734 5.7e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MDBPHIKD_00735 1.9e-200 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MDBPHIKD_00736 1.9e-115 S Membrane
MDBPHIKD_00737 6.9e-127 O Zinc-dependent metalloprotease
MDBPHIKD_00738 1.5e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDBPHIKD_00739 7.7e-160 metQ_4 P Belongs to the nlpA lipoprotein family
MDBPHIKD_00741 3.5e-238 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDBPHIKD_00742 2.5e-129 narI 1.7.5.1 C Nitrate reductase
MDBPHIKD_00743 7.9e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
MDBPHIKD_00744 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
MDBPHIKD_00745 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDBPHIKD_00746 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
MDBPHIKD_00747 3.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MDBPHIKD_00748 3.2e-228 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
MDBPHIKD_00749 7.9e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MDBPHIKD_00750 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MDBPHIKD_00751 5.1e-44
MDBPHIKD_00752 5.1e-190 comP 2.7.13.3 F Sensor histidine kinase
MDBPHIKD_00753 9.8e-115 nreC K PFAM regulatory protein LuxR
MDBPHIKD_00754 1.6e-18
MDBPHIKD_00755 1.4e-181
MDBPHIKD_00756 1.7e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
MDBPHIKD_00757 3.9e-218 narK P Transporter, major facilitator family protein
MDBPHIKD_00758 4.9e-35 moaD 2.8.1.12 H ThiS family
MDBPHIKD_00759 2.5e-64 moaE 2.8.1.12 H MoaE protein
MDBPHIKD_00760 3.6e-76 S Flavodoxin
MDBPHIKD_00761 1.8e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDBPHIKD_00762 6.3e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
MDBPHIKD_00763 8.5e-174 fecB P Periplasmic binding protein
MDBPHIKD_00764 5.4e-178 M Glycosyltransferase like family 2
MDBPHIKD_00765 3e-27
MDBPHIKD_00766 1e-133 M repeat protein
MDBPHIKD_00767 1e-157 3.2.1.96, 3.5.1.28 GH73 M repeat protein
MDBPHIKD_00768 1.8e-40 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
MDBPHIKD_00769 3e-24
MDBPHIKD_00770 1.1e-19 relB L Addiction module antitoxin, RelB DinJ family
MDBPHIKD_00771 7.5e-91 XK27_08850 J Aminoacyl-tRNA editing domain
MDBPHIKD_00772 1e-56 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MDBPHIKD_00773 7.7e-199 V Beta-lactamase
MDBPHIKD_00774 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDBPHIKD_00775 1.7e-122 yhiD S MgtC family
MDBPHIKD_00776 4e-121 S GyrI-like small molecule binding domain
MDBPHIKD_00778 6.1e-125 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDBPHIKD_00779 3.2e-50 azlD E Branched-chain amino acid transport
MDBPHIKD_00780 2e-121 azlC E azaleucine resistance protein AzlC
MDBPHIKD_00781 2.6e-266 K Aminotransferase class I and II
MDBPHIKD_00782 1.9e-305 S amidohydrolase
MDBPHIKD_00783 1.6e-165 S reductase
MDBPHIKD_00784 1.6e-93 2.3.1.183 M Acetyltransferase GNAT family
MDBPHIKD_00785 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDBPHIKD_00786 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
MDBPHIKD_00787 4.8e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDBPHIKD_00788 0.0 asnB 6.3.5.4 E Asparagine synthase
MDBPHIKD_00789 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDBPHIKD_00790 7.1e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDBPHIKD_00791 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MDBPHIKD_00797 1e-148 S Hydrolases of the alpha beta superfamily
MDBPHIKD_00798 1.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
MDBPHIKD_00799 3.4e-77 ctsR K Belongs to the CtsR family
MDBPHIKD_00800 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDBPHIKD_00801 1e-110 K Bacterial regulatory proteins, tetR family
MDBPHIKD_00802 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDBPHIKD_00803 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDBPHIKD_00804 1.5e-201 ykiI
MDBPHIKD_00805 2.7e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MDBPHIKD_00806 5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDBPHIKD_00807 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDBPHIKD_00808 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDBPHIKD_00809 5.4e-200 L Transposase
MDBPHIKD_00810 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MDBPHIKD_00811 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDBPHIKD_00812 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
MDBPHIKD_00813 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDBPHIKD_00814 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDBPHIKD_00815 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDBPHIKD_00816 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDBPHIKD_00817 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDBPHIKD_00818 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDBPHIKD_00819 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
MDBPHIKD_00820 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDBPHIKD_00821 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDBPHIKD_00822 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDBPHIKD_00823 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDBPHIKD_00824 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDBPHIKD_00825 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDBPHIKD_00826 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDBPHIKD_00827 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDBPHIKD_00828 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDBPHIKD_00829 2.9e-24 rpmD J Ribosomal protein L30
MDBPHIKD_00830 6.8e-64 rplO J Binds to the 23S rRNA
MDBPHIKD_00831 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDBPHIKD_00832 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDBPHIKD_00833 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDBPHIKD_00834 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MDBPHIKD_00835 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDBPHIKD_00836 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDBPHIKD_00837 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDBPHIKD_00838 1.1e-62 rplQ J Ribosomal protein L17
MDBPHIKD_00839 1.9e-147 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDBPHIKD_00840 1.5e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDBPHIKD_00841 1.2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDBPHIKD_00842 1.2e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDBPHIKD_00843 9.1e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDBPHIKD_00844 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MDBPHIKD_00845 5.5e-141 IQ reductase
MDBPHIKD_00846 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
MDBPHIKD_00847 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDBPHIKD_00848 9.4e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDBPHIKD_00849 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MDBPHIKD_00850 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDBPHIKD_00851 3.3e-203 camS S sex pheromone
MDBPHIKD_00852 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDBPHIKD_00853 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDBPHIKD_00854 2.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDBPHIKD_00855 3.5e-188 yegS 2.7.1.107 G Lipid kinase
MDBPHIKD_00857 6.1e-268 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDBPHIKD_00858 5.4e-236
MDBPHIKD_00859 3.1e-300 hsdM 2.1.1.72 V type I restriction-modification system
MDBPHIKD_00860 8.2e-122 3.1.21.3 V Type I restriction modification DNA specificity domain
MDBPHIKD_00861 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
MDBPHIKD_00862 6.3e-90 entB 3.5.1.19 Q Isochorismatase family
MDBPHIKD_00863 2.8e-44 L transposase and inactivated derivatives, IS30 family
MDBPHIKD_00864 5.6e-126 L PFAM Integrase catalytic region
MDBPHIKD_00866 5e-167 I alpha/beta hydrolase fold
MDBPHIKD_00867 5.1e-116 frnE Q DSBA-like thioredoxin domain
MDBPHIKD_00868 3.6e-55
MDBPHIKD_00877 4.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MDBPHIKD_00878 1.6e-140 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MDBPHIKD_00879 6.5e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MDBPHIKD_00880 3.2e-261 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MDBPHIKD_00881 1e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDBPHIKD_00882 2.1e-76 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MDBPHIKD_00883 5.6e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDBPHIKD_00884 1.3e-131 IQ reductase
MDBPHIKD_00885 3.3e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MDBPHIKD_00886 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDBPHIKD_00887 3.8e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDBPHIKD_00888 4.2e-77 marR K Transcriptional regulator, MarR family
MDBPHIKD_00889 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDBPHIKD_00891 4.6e-202 xerS L Belongs to the 'phage' integrase family
MDBPHIKD_00892 1.5e-32 L PFAM Integrase catalytic region
MDBPHIKD_00893 1.2e-213 L PFAM Integrase catalytic region
MDBPHIKD_00894 4.8e-96 K Acetyltransferase (GNAT) domain
MDBPHIKD_00895 1.2e-160 S Alpha beta hydrolase
MDBPHIKD_00896 3.1e-161 gspA M family 8
MDBPHIKD_00897 6e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDBPHIKD_00898 9.4e-94
MDBPHIKD_00899 1.7e-162 degV S EDD domain protein, DegV family
MDBPHIKD_00900 0.0 FbpA K Fibronectin-binding protein
MDBPHIKD_00901 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MDBPHIKD_00902 4.3e-208 carA 6.3.5.5 F Belongs to the CarA family
MDBPHIKD_00903 4.8e-176 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDBPHIKD_00904 1.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDBPHIKD_00905 1.5e-65 esbA S Family of unknown function (DUF5322)
MDBPHIKD_00906 6.9e-71 rnhA 3.1.26.4 L Ribonuclease HI
MDBPHIKD_00907 1.2e-182 M lysozyme activity
MDBPHIKD_00908 2.2e-15 S Bacteriophage holin family
MDBPHIKD_00909 4.8e-12
MDBPHIKD_00911 0.0 GT2,GT4 LM gp58-like protein
MDBPHIKD_00912 4.2e-51
MDBPHIKD_00913 0.0 M Phage tail tape measure protein TP901
MDBPHIKD_00914 2e-32
MDBPHIKD_00915 9e-58
MDBPHIKD_00916 5.9e-72 S Phage tail tube protein, TTP
MDBPHIKD_00917 2.1e-50
MDBPHIKD_00918 3.6e-78
MDBPHIKD_00919 1.3e-57
MDBPHIKD_00920 3.6e-35
MDBPHIKD_00921 1e-166 S Phage major capsid protein E
MDBPHIKD_00922 3.1e-54
MDBPHIKD_00923 5.8e-51 S Domain of unknown function (DUF4355)
MDBPHIKD_00924 2.4e-150 S Phage Mu protein F like protein
MDBPHIKD_00925 2e-216 S Phage portal protein, SPP1 Gp6-like
MDBPHIKD_00926 3.3e-215 S Terminase-like family
MDBPHIKD_00927 2.9e-106 xtmA L Terminase small subunit
MDBPHIKD_00930 3.1e-65 K Domain of unknown function (DUF4417)
MDBPHIKD_00935 7.6e-22
MDBPHIKD_00936 1e-46 gepA S Protein of unknown function (DUF4065)
MDBPHIKD_00937 6.7e-36
MDBPHIKD_00940 6.5e-67 rusA L Endodeoxyribonuclease RusA
MDBPHIKD_00941 2.7e-31
MDBPHIKD_00942 2.6e-34
MDBPHIKD_00947 1.2e-15
MDBPHIKD_00950 8.5e-40 S ORF6C domain
MDBPHIKD_00953 3.6e-57
MDBPHIKD_00954 1.9e-118 L Psort location Cytoplasmic, score
MDBPHIKD_00955 3e-60 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
MDBPHIKD_00956 1.2e-78 recT L RecT family
MDBPHIKD_00961 1.2e-29
MDBPHIKD_00965 1.4e-15 S Hypothetical protein (DUF2513)
MDBPHIKD_00968 4.4e-26 3.4.21.88 K Helix-turn-helix domain
MDBPHIKD_00969 5.9e-70 S Pfam:DUF955
MDBPHIKD_00971 5.4e-09
MDBPHIKD_00972 6e-42
MDBPHIKD_00973 1.4e-81 S AAA ATPase domain
MDBPHIKD_00974 1.2e-87 vsr 2.1.1.37 L DNA mismatch endonuclease Vsr
MDBPHIKD_00975 2.7e-49
MDBPHIKD_00976 2.6e-99 L Belongs to the 'phage' integrase family
MDBPHIKD_00977 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MDBPHIKD_00978 7.7e-85 F Belongs to the NrdI family
MDBPHIKD_00979 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDBPHIKD_00980 1.6e-105 ypsA S Belongs to the UPF0398 family
MDBPHIKD_00981 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDBPHIKD_00982 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MDBPHIKD_00983 1.4e-162 EG EamA-like transporter family
MDBPHIKD_00984 5.1e-125 dnaD L DnaD domain protein
MDBPHIKD_00985 1.8e-87 ypmB S Protein conserved in bacteria
MDBPHIKD_00986 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MDBPHIKD_00987 2.1e-174 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MDBPHIKD_00988 4.6e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MDBPHIKD_00989 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MDBPHIKD_00990 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDBPHIKD_00991 1.9e-89 S Protein of unknown function (DUF1440)
MDBPHIKD_00992 1.9e-38 3.6.1.13, 3.6.1.55 F NUDIX domain
MDBPHIKD_00993 9.1e-299 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MDBPHIKD_00994 2.5e-36 copZ P PFAM Heavy metal transport detoxification protein
MDBPHIKD_00995 4.8e-99 dps P Belongs to the Dps family
MDBPHIKD_00996 3.8e-111 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MDBPHIKD_00998 8.6e-184 L Plasmid pRiA4b ORF-3-like protein
MDBPHIKD_01000 6.3e-61 S Protein of unknown function (DUF3021)
MDBPHIKD_01001 1.4e-75 K LytTr DNA-binding domain
MDBPHIKD_01002 1.7e-146 cylB V ABC-2 type transporter
MDBPHIKD_01003 1.1e-158 cylA V ABC transporter
MDBPHIKD_01004 5.7e-52
MDBPHIKD_01005 0.0 XK27_08510 L Type III restriction protein res subunit
MDBPHIKD_01006 3.1e-104 S PFAM Archaeal ATPase
MDBPHIKD_01007 7.9e-70 S PFAM Archaeal ATPase
MDBPHIKD_01008 4.4e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDBPHIKD_01009 2.3e-207 amtB P ammonium transporter
MDBPHIKD_01010 3e-256 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
MDBPHIKD_01011 1e-84 yvbK 3.1.3.25 K GNAT family
MDBPHIKD_01012 2.5e-92
MDBPHIKD_01013 9.7e-45 pnb C nitroreductase
MDBPHIKD_01014 2.7e-54 pnb C nitroreductase
MDBPHIKD_01015 2.2e-84 ogt 2.1.1.63 L Methyltransferase
MDBPHIKD_01016 9.5e-132 L transposase, IS605 OrfB family
MDBPHIKD_01017 4.2e-77 XK27_00915 C Luciferase-like monooxygenase
MDBPHIKD_01018 1.1e-156 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MDBPHIKD_01019 5.6e-69 S Protein of unknown function (DUF3021)
MDBPHIKD_01020 2.9e-78 K LytTr DNA-binding domain
MDBPHIKD_01021 2.5e-97 K Acetyltransferase (GNAT) family
MDBPHIKD_01022 3.7e-22
MDBPHIKD_01023 7.6e-121 ybhL S Belongs to the BI1 family
MDBPHIKD_01024 5.8e-82 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
MDBPHIKD_01025 6.3e-201 S Protein of unknown function (DUF3114)
MDBPHIKD_01026 1.3e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MDBPHIKD_01027 2.7e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MDBPHIKD_01028 1.3e-110 yvdD 3.2.2.10 S Belongs to the LOG family
MDBPHIKD_01029 7e-62 S Domain of unknown function (DUF4828)
MDBPHIKD_01030 1.2e-191 mocA S Oxidoreductase
MDBPHIKD_01031 3.6e-233 yfmL 3.6.4.13 L DEAD DEAH box helicase
MDBPHIKD_01033 3.3e-211 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDBPHIKD_01034 3.6e-54
MDBPHIKD_01035 1.5e-74 gtcA S Teichoic acid glycosylation protein
MDBPHIKD_01036 2.1e-79 fld C Flavodoxin
MDBPHIKD_01037 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
MDBPHIKD_01038 8.4e-223 arcT 2.6.1.1 E Aminotransferase
MDBPHIKD_01039 1.7e-257 E Arginine ornithine antiporter
MDBPHIKD_01040 1.1e-281 yjeM E Amino Acid
MDBPHIKD_01041 8.5e-154 yihY S Belongs to the UPF0761 family
MDBPHIKD_01042 5e-34 S Protein of unknown function (DUF2922)
MDBPHIKD_01043 3.2e-30
MDBPHIKD_01044 9.3e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
MDBPHIKD_01045 1.1e-149 cps1D M Domain of unknown function (DUF4422)
MDBPHIKD_01046 9.8e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MDBPHIKD_01047 1.7e-122 rfbP 2.7.8.6 M Bacterial sugar transferase
MDBPHIKD_01048 6e-221 glf 5.4.99.9 M UDP-galactopyranose mutase
MDBPHIKD_01049 4.3e-217 cps3F
MDBPHIKD_01050 1.4e-105 M biosynthesis protein
MDBPHIKD_01051 4.9e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
MDBPHIKD_01052 9.3e-200 waaB GT4 M Glycosyl transferases group 1
MDBPHIKD_01053 9.6e-194 M transferase activity, transferring glycosyl groups
MDBPHIKD_01054 1.7e-196 S enterobacterial common antigen metabolic process
MDBPHIKD_01055 1.6e-141 acmD M repeat protein
MDBPHIKD_01056 8.7e-116 lssY 3.6.1.27 I Acid phosphatase homologues
MDBPHIKD_01057 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MDBPHIKD_01058 4.2e-231 clcA_2 P Chloride transporter, ClC family
MDBPHIKD_01059 6.5e-119 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MDBPHIKD_01060 4.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDBPHIKD_01061 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDBPHIKD_01062 1.6e-51
MDBPHIKD_01063 0.0 S SEC-C Motif Domain Protein
MDBPHIKD_01064 1.1e-294 L Transposase IS66 family
MDBPHIKD_01065 1.1e-52 XK27_01125 L PFAM IS66 Orf2 family protein
MDBPHIKD_01067 5.9e-88 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MDBPHIKD_01068 1.2e-76
MDBPHIKD_01069 1.2e-180
MDBPHIKD_01070 1.6e-66 XK27_01125 L PFAM IS66 Orf2 family protein
MDBPHIKD_01072 7e-184 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MDBPHIKD_01073 4.4e-163 rrmA 2.1.1.187 H Methyltransferase
MDBPHIKD_01074 4.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDBPHIKD_01075 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MDBPHIKD_01076 1.2e-10 S Protein of unknown function (DUF4044)
MDBPHIKD_01077 7.8e-58
MDBPHIKD_01078 3.1e-77 mraZ K Belongs to the MraZ family
MDBPHIKD_01079 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDBPHIKD_01080 1.5e-56 ftsL D Cell division protein FtsL
MDBPHIKD_01081 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MDBPHIKD_01082 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDBPHIKD_01083 2.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDBPHIKD_01084 9.2e-206 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDBPHIKD_01085 3.2e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDBPHIKD_01086 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDBPHIKD_01087 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDBPHIKD_01088 1.2e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDBPHIKD_01089 8.3e-41 yggT S YGGT family
MDBPHIKD_01090 1.3e-145 ylmH S S4 domain protein
MDBPHIKD_01091 6.4e-38 divIVA D DivIVA domain protein
MDBPHIKD_01092 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDBPHIKD_01093 7.2e-81 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MDBPHIKD_01094 9.6e-75 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MDBPHIKD_01095 3.6e-53 L transposase, IS605 OrfB family
MDBPHIKD_01096 2.1e-67 ywiB S Domain of unknown function (DUF1934)
MDBPHIKD_01097 1.5e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDBPHIKD_01098 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDBPHIKD_01099 6.1e-53 L transposase, IS605 OrfB family
MDBPHIKD_01100 2e-94
MDBPHIKD_01101 2.2e-69 K Transcriptional regulator, HxlR family
MDBPHIKD_01102 2.3e-171 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDBPHIKD_01103 6e-22 epsB M biosynthesis protein
MDBPHIKD_01104 7.9e-168 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDBPHIKD_01105 1.8e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDBPHIKD_01106 2.8e-264 S Protein of unknown function (DUF2971)
MDBPHIKD_01107 0.0 S KAP family P-loop domain
MDBPHIKD_01108 2.3e-306 S AAA domain, putative AbiEii toxin, Type IV TA system
MDBPHIKD_01109 4.8e-207 3.6.4.12 L DNA helicase
MDBPHIKD_01110 3.1e-231 L Integrase core domain
MDBPHIKD_01111 1.3e-139 L Bacterial dnaA protein
MDBPHIKD_01112 7e-159
MDBPHIKD_01113 3.5e-238 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDBPHIKD_01114 2.5e-39 S Cytochrome B5
MDBPHIKD_01115 2e-27
MDBPHIKD_01116 3.4e-82 S Domain of unknown function (DUF4767)
MDBPHIKD_01117 3.3e-13
MDBPHIKD_01118 1.4e-212 cytX U Belongs to the purine-cytosine permease (2.A.39) family
MDBPHIKD_01119 1.9e-97 wecD3 K PFAM GCN5-related N-acetyltransferase
MDBPHIKD_01120 7.3e-80
MDBPHIKD_01121 4.2e-123 M Lysin motif
MDBPHIKD_01122 7.1e-201 EGP Major facilitator Superfamily
MDBPHIKD_01123 1.2e-85 ywlG S Belongs to the UPF0340 family
MDBPHIKD_01124 3.2e-161 spoU 2.1.1.185 J Methyltransferase
MDBPHIKD_01125 1.3e-224 oxlT P Major Facilitator Superfamily
MDBPHIKD_01126 4.2e-149 L Belongs to the 'phage' integrase family
MDBPHIKD_01127 3.9e-56 L Belongs to the 'phage' integrase family
MDBPHIKD_01128 1.1e-33 S Domain of unknown function (DUF3173)
MDBPHIKD_01130 0.0
MDBPHIKD_01131 1.4e-172
MDBPHIKD_01132 2.1e-85 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MDBPHIKD_01133 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MDBPHIKD_01134 1.6e-260 G Major Facilitator Superfamily
MDBPHIKD_01135 4.2e-49 V DNA modification
MDBPHIKD_01136 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MDBPHIKD_01138 1.7e-226 S cog cog1373
MDBPHIKD_01139 3.3e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MDBPHIKD_01140 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDBPHIKD_01141 7e-161 EG EamA-like transporter family
MDBPHIKD_01142 5e-27 Q pyridine nucleotide-disulphide oxidoreductase
MDBPHIKD_01143 6.1e-53 L transposase, IS605 OrfB family
MDBPHIKD_01144 2.1e-29 L Transposase
MDBPHIKD_01145 1.7e-57 L PFAM Integrase catalytic region
MDBPHIKD_01146 1.1e-96 L Helix-turn-helix domain
MDBPHIKD_01147 1.1e-115 L PFAM Integrase, catalytic core
MDBPHIKD_01148 7.8e-38 L Helix-turn-helix domain
MDBPHIKD_01149 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
MDBPHIKD_01151 3.1e-103 M NlpC P60 family protein
MDBPHIKD_01152 0.0 uup S ABC transporter, ATP-binding protein
MDBPHIKD_01153 6.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDBPHIKD_01155 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDBPHIKD_01156 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDBPHIKD_01157 4.2e-86 S Aminoacyl-tRNA editing domain
MDBPHIKD_01158 4.3e-305 ybeC E amino acid
MDBPHIKD_01159 0.0 ydaO E amino acid
MDBPHIKD_01160 9.2e-40
MDBPHIKD_01161 3.3e-68 rmaI K Transcriptional regulator
MDBPHIKD_01162 1.3e-249 EGP Major facilitator Superfamily
MDBPHIKD_01163 2e-112 yvyE 3.4.13.9 S YigZ family
MDBPHIKD_01164 2.3e-259 comFA L Helicase C-terminal domain protein
MDBPHIKD_01165 2.6e-126 comFC S Competence protein
MDBPHIKD_01166 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDBPHIKD_01167 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDBPHIKD_01168 9.2e-189 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDBPHIKD_01169 2.4e-32 KT PspC domain protein
MDBPHIKD_01170 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MDBPHIKD_01171 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDBPHIKD_01172 1.3e-159 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDBPHIKD_01173 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MDBPHIKD_01174 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDBPHIKD_01175 2.4e-138 yrjD S LUD domain
MDBPHIKD_01176 4.4e-296 lutB C 4Fe-4S dicluster domain
MDBPHIKD_01177 1.9e-169 lutA C Cysteine-rich domain
MDBPHIKD_01178 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDBPHIKD_01179 1.3e-221 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MDBPHIKD_01180 1.6e-165 aatB ET PFAM extracellular solute-binding protein, family 3
MDBPHIKD_01181 9.1e-84 ykhA 3.1.2.20 I Thioesterase superfamily
MDBPHIKD_01182 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDBPHIKD_01183 2.3e-116 yfbR S HD containing hydrolase-like enzyme
MDBPHIKD_01184 1.5e-13
MDBPHIKD_01185 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDBPHIKD_01186 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDBPHIKD_01187 2.4e-245 steT E amino acid
MDBPHIKD_01188 1.7e-162 rapZ S Displays ATPase and GTPase activities
MDBPHIKD_01189 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MDBPHIKD_01190 2.4e-170 whiA K May be required for sporulation
MDBPHIKD_01192 8.8e-15
MDBPHIKD_01193 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDBPHIKD_01194 1.8e-123 L Transposase
MDBPHIKD_01195 4.9e-87
MDBPHIKD_01197 1.8e-289 L Transposase IS66 family
MDBPHIKD_01198 2.3e-65 XK27_01125 L PFAM IS66 Orf2 family protein
MDBPHIKD_01201 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDBPHIKD_01202 2.8e-170 yniA G Phosphotransferase enzyme family
MDBPHIKD_01203 1.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDBPHIKD_01204 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDBPHIKD_01205 9.3e-53
MDBPHIKD_01206 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDBPHIKD_01207 1.6e-182 prmA J Ribosomal protein L11 methyltransferase
MDBPHIKD_01208 7.5e-58
MDBPHIKD_01210 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDBPHIKD_01211 1.7e-201 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MDBPHIKD_01212 7.9e-279 pipD E Dipeptidase
MDBPHIKD_01213 9.2e-24 3.4.21.88 K Peptidase S24-like
MDBPHIKD_01214 1.4e-10 3.4.21.88 K Peptidase S24-like
MDBPHIKD_01215 1e-81
MDBPHIKD_01216 4.7e-76
MDBPHIKD_01217 6.4e-13
MDBPHIKD_01218 8.1e-142
MDBPHIKD_01219 5.4e-225 3.6.4.12 L Belongs to the 'phage' integrase family
MDBPHIKD_01220 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDBPHIKD_01221 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDBPHIKD_01222 0.0 dnaK O Heat shock 70 kDa protein
MDBPHIKD_01223 1.2e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDBPHIKD_01224 1.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDBPHIKD_01225 2e-64
MDBPHIKD_01226 1.9e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MDBPHIKD_01227 1.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDBPHIKD_01228 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDBPHIKD_01229 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDBPHIKD_01230 4.5e-49 ylxQ J ribosomal protein
MDBPHIKD_01231 1e-44 ylxR K Protein of unknown function (DUF448)
MDBPHIKD_01232 1.2e-216 nusA K Participates in both transcription termination and antitermination
MDBPHIKD_01233 1.4e-83 rimP J Required for maturation of 30S ribosomal subunits
MDBPHIKD_01234 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDBPHIKD_01235 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDBPHIKD_01236 9.8e-236 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MDBPHIKD_01237 3.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
MDBPHIKD_01238 4.5e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDBPHIKD_01239 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDBPHIKD_01240 3.2e-176
MDBPHIKD_01241 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDBPHIKD_01242 1.2e-246 purD 6.3.4.13 F Belongs to the GARS family
MDBPHIKD_01243 2.2e-298 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MDBPHIKD_01244 1.6e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDBPHIKD_01245 6.6e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MDBPHIKD_01246 2.8e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDBPHIKD_01247 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDBPHIKD_01248 4.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDBPHIKD_01249 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDBPHIKD_01250 6.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MDBPHIKD_01251 1.1e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDBPHIKD_01252 7.8e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDBPHIKD_01253 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDBPHIKD_01254 3.5e-134 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MDBPHIKD_01255 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MDBPHIKD_01256 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MDBPHIKD_01257 1.1e-173 K AI-2E family transporter
MDBPHIKD_01258 2.9e-237 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MDBPHIKD_01259 1.6e-117 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
MDBPHIKD_01260 7.9e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDBPHIKD_01261 4.6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDBPHIKD_01262 2.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDBPHIKD_01263 3e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDBPHIKD_01264 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MDBPHIKD_01265 4.4e-16 K LysR substrate binding domain
MDBPHIKD_01266 1.4e-114 K DNA-binding transcription factor activity
MDBPHIKD_01267 1.6e-52 azlD S branched-chain amino acid
MDBPHIKD_01268 9.7e-137 azlC E AzlC protein
MDBPHIKD_01269 2e-203 hpk31 2.7.13.3 T Histidine kinase
MDBPHIKD_01270 3.8e-125 K response regulator
MDBPHIKD_01271 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDBPHIKD_01272 3.9e-173 deoR K sugar-binding domain protein
MDBPHIKD_01273 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MDBPHIKD_01274 9.6e-239 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
MDBPHIKD_01275 1.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MDBPHIKD_01276 4.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDBPHIKD_01277 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
MDBPHIKD_01278 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDBPHIKD_01279 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
MDBPHIKD_01280 5.9e-155 spo0J K Belongs to the ParB family
MDBPHIKD_01281 3.6e-140 soj D Sporulation initiation inhibitor
MDBPHIKD_01282 7.4e-151 noc K Belongs to the ParB family
MDBPHIKD_01283 5.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MDBPHIKD_01284 1.5e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MDBPHIKD_01285 2.7e-171 rihC 3.2.2.1 F Nucleoside
MDBPHIKD_01286 1e-218 nupG F Nucleoside transporter
MDBPHIKD_01287 7.7e-223 cycA E Amino acid permease
MDBPHIKD_01288 8.5e-139 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDBPHIKD_01289 1e-265 glnP P ABC transporter
MDBPHIKD_01290 2.2e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDBPHIKD_01291 6.8e-297 fhaB M Rib/alpha-like repeat
MDBPHIKD_01294 9e-30 A chlorophyll binding
MDBPHIKD_01306 5.1e-125 srtA 3.4.22.70 M sortase family
MDBPHIKD_01307 2.7e-168 S Alpha/beta hydrolase of unknown function (DUF915)
MDBPHIKD_01308 6.1e-241 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDBPHIKD_01309 4.6e-41 rpmE2 J Ribosomal protein L31
MDBPHIKD_01310 8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDBPHIKD_01311 5.6e-32 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDBPHIKD_01313 2.1e-26
MDBPHIKD_01314 5.3e-264 pgi 5.3.1.9 G Belongs to the GPI family
MDBPHIKD_01315 1.4e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
MDBPHIKD_01316 5.7e-155 glcU U sugar transport
MDBPHIKD_01317 8.1e-274 yclK 2.7.13.3 T Histidine kinase
MDBPHIKD_01318 3.8e-136 K response regulator
MDBPHIKD_01320 1.8e-78 lytE M Lysin motif
MDBPHIKD_01321 8.9e-150 XK27_02985 S Cof-like hydrolase
MDBPHIKD_01322 2.1e-79 K Transcriptional regulator
MDBPHIKD_01323 0.0 oatA I Acyltransferase
MDBPHIKD_01324 8.7e-53
MDBPHIKD_01325 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDBPHIKD_01326 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDBPHIKD_01327 1.2e-126 ybbR S YbbR-like protein
MDBPHIKD_01328 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDBPHIKD_01329 3.7e-249 fucP G Major Facilitator Superfamily
MDBPHIKD_01330 6e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDBPHIKD_01331 1.2e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDBPHIKD_01332 7.3e-169 murB 1.3.1.98 M Cell wall formation
MDBPHIKD_01333 9.3e-103 dnaQ 2.7.7.7 L DNA polymerase III
MDBPHIKD_01334 8.9e-77 S PAS domain
MDBPHIKD_01335 6.1e-88 K Acetyltransferase (GNAT) domain
MDBPHIKD_01336 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MDBPHIKD_01337 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MDBPHIKD_01338 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDBPHIKD_01339 6.3e-105 yxjI
MDBPHIKD_01340 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDBPHIKD_01341 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDBPHIKD_01342 2.1e-148 est 3.1.1.1 S Serine aminopeptidase, S33
MDBPHIKD_01343 1.8e-34 secG U Preprotein translocase
MDBPHIKD_01344 5.6e-294 clcA P chloride
MDBPHIKD_01345 1.9e-245 yifK E Amino acid permease
MDBPHIKD_01346 0.0 helD 3.6.4.12 L DNA helicase
MDBPHIKD_01347 3.6e-117 dedA S SNARE associated Golgi protein
MDBPHIKD_01348 5e-127 3.1.3.73 G phosphoglycerate mutase
MDBPHIKD_01349 1.3e-235 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDBPHIKD_01350 6.6e-35 S Transglycosylase associated protein
MDBPHIKD_01352 1.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDBPHIKD_01353 9.5e-239 V domain protein
MDBPHIKD_01354 1.6e-94 K Transcriptional regulator (TetR family)
MDBPHIKD_01355 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
MDBPHIKD_01356 2e-152
MDBPHIKD_01357 3.1e-17 3.2.1.14 GH18
MDBPHIKD_01358 1.5e-82 zur P Belongs to the Fur family
MDBPHIKD_01359 5.2e-104 gmk2 2.7.4.8 F Guanylate kinase
MDBPHIKD_01360 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MDBPHIKD_01361 1.1e-256 yfnA E Amino Acid
MDBPHIKD_01362 3.9e-232 EGP Sugar (and other) transporter
MDBPHIKD_01363 1e-232
MDBPHIKD_01364 2.3e-209 potD P ABC transporter
MDBPHIKD_01365 4.9e-140 potC P ABC transporter permease
MDBPHIKD_01366 4.5e-146 potB P ABC transporter permease
MDBPHIKD_01367 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDBPHIKD_01368 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDBPHIKD_01369 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MDBPHIKD_01370 0.0 pacL 3.6.3.8 P P-type ATPase
MDBPHIKD_01371 2.6e-85 dps P Belongs to the Dps family
MDBPHIKD_01372 6.7e-254 yagE E amino acid
MDBPHIKD_01373 2.5e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MDBPHIKD_01374 5.7e-30 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDBPHIKD_01375 2e-25 L Helix-turn-helix domain
MDBPHIKD_01376 5.1e-87 L Helix-turn-helix domain
MDBPHIKD_01377 1e-127 L hmm pf00665
MDBPHIKD_01378 4.7e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MDBPHIKD_01379 2.1e-182 iunH2 3.2.2.1 F nucleoside hydrolase
MDBPHIKD_01380 2.5e-138 IQ KR domain
MDBPHIKD_01381 6.6e-134 S membrane transporter protein
MDBPHIKD_01382 1.9e-98 S ABC-type cobalt transport system, permease component
MDBPHIKD_01383 1.6e-260 cbiO1 S ABC transporter, ATP-binding protein
MDBPHIKD_01384 2.6e-115 P Cobalt transport protein
MDBPHIKD_01385 1.6e-52 yvlA
MDBPHIKD_01386 0.0 yjcE P Sodium proton antiporter
MDBPHIKD_01387 2.2e-52 ypaA S Protein of unknown function (DUF1304)
MDBPHIKD_01388 2.1e-190 D Alpha beta
MDBPHIKD_01389 1e-72 K Transcriptional regulator
MDBPHIKD_01390 2.6e-163
MDBPHIKD_01391 8.8e-184 1.6.5.5 C Zinc-binding dehydrogenase
MDBPHIKD_01392 3.5e-258 G PTS system Galactitol-specific IIC component
MDBPHIKD_01393 8.2e-213 EGP Major facilitator Superfamily
MDBPHIKD_01394 1.5e-137 V ABC transporter
MDBPHIKD_01395 4.5e-121
MDBPHIKD_01396 5.2e-14
MDBPHIKD_01397 1.9e-63
MDBPHIKD_01398 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
MDBPHIKD_01399 5.1e-81 uspA T universal stress protein
MDBPHIKD_01400 0.0 tetP J elongation factor G
MDBPHIKD_01401 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
MDBPHIKD_01402 1.3e-35 ynzC S UPF0291 protein
MDBPHIKD_01403 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDBPHIKD_01404 1.5e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MDBPHIKD_01405 8.4e-130 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDBPHIKD_01407 2.5e-88
MDBPHIKD_01408 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDBPHIKD_01409 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MDBPHIKD_01410 2e-157 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MDBPHIKD_01411 9.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDBPHIKD_01412 1.2e-249 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDBPHIKD_01413 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDBPHIKD_01414 7.6e-09
MDBPHIKD_01415 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MDBPHIKD_01416 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
MDBPHIKD_01417 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDBPHIKD_01418 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDBPHIKD_01419 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDBPHIKD_01420 4.9e-165 S Tetratricopeptide repeat
MDBPHIKD_01421 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDBPHIKD_01422 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDBPHIKD_01423 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
MDBPHIKD_01424 2.5e-149 holA 2.7.7.7 L DNA polymerase III delta subunit
MDBPHIKD_01425 0.0 comEC S Competence protein ComEC
MDBPHIKD_01426 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
MDBPHIKD_01427 8.1e-82 comEA L Competence protein ComEA
MDBPHIKD_01428 7.1e-200 ylbL T Belongs to the peptidase S16 family
MDBPHIKD_01429 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDBPHIKD_01430 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MDBPHIKD_01431 1e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MDBPHIKD_01432 8.2e-224 ftsW D Belongs to the SEDS family
MDBPHIKD_01433 0.0 typA T GTP-binding protein TypA
MDBPHIKD_01434 5.7e-138 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MDBPHIKD_01435 6.1e-48 yktA S Belongs to the UPF0223 family
MDBPHIKD_01436 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
MDBPHIKD_01437 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDBPHIKD_01438 6.2e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MDBPHIKD_01439 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MDBPHIKD_01440 5.6e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDBPHIKD_01441 3.6e-82
MDBPHIKD_01442 9.8e-32 ykzG S Belongs to the UPF0356 family
MDBPHIKD_01443 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
MDBPHIKD_01444 5.7e-29
MDBPHIKD_01445 3.7e-143 mltD CBM50 M NlpC P60 family protein
MDBPHIKD_01447 7.7e-58
MDBPHIKD_01448 1.5e-211 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MDBPHIKD_01449 5.9e-220 EG GntP family permease
MDBPHIKD_01450 2.9e-27 KT Putative sugar diacid recognition
MDBPHIKD_01451 1.4e-32 KT Putative sugar diacid recognition
MDBPHIKD_01452 6.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDBPHIKD_01453 2.6e-222 patA 2.6.1.1 E Aminotransferase
MDBPHIKD_01454 2.3e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDBPHIKD_01455 1.6e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDBPHIKD_01456 7e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDBPHIKD_01457 2.1e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDBPHIKD_01458 1.9e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDBPHIKD_01459 7.2e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
MDBPHIKD_01460 2.7e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDBPHIKD_01461 2.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDBPHIKD_01462 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDBPHIKD_01463 3.4e-118 S Repeat protein
MDBPHIKD_01464 3.4e-123 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MDBPHIKD_01465 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDBPHIKD_01466 7.5e-58 XK27_04120 S Putative amino acid metabolism
MDBPHIKD_01467 2.9e-218 iscS 2.8.1.7 E Aminotransferase class V
MDBPHIKD_01468 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDBPHIKD_01470 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MDBPHIKD_01471 4.2e-32 cspA K Cold shock protein
MDBPHIKD_01472 1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDBPHIKD_01473 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MDBPHIKD_01474 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MDBPHIKD_01475 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDBPHIKD_01476 7e-93 lemA S LemA family
MDBPHIKD_01477 8.9e-159 htpX O Belongs to the peptidase M48B family
MDBPHIKD_01478 5.2e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDBPHIKD_01479 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDBPHIKD_01480 1.4e-153 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MDBPHIKD_01481 2.4e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
MDBPHIKD_01484 5e-22 S Phage derived protein Gp49-like (DUF891)
MDBPHIKD_01485 1.7e-47 L Belongs to the 'phage' integrase family
MDBPHIKD_01487 2.3e-36 S Lipopolysaccharide assembly protein A domain
MDBPHIKD_01488 3.7e-159 3.1.3.102, 3.1.3.104 S hydrolase
MDBPHIKD_01489 1.2e-90 ntd 2.4.2.6 F Nucleoside
MDBPHIKD_01490 7.5e-21
MDBPHIKD_01491 1.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
MDBPHIKD_01492 4.7e-114 yviA S Protein of unknown function (DUF421)
MDBPHIKD_01493 1.9e-29 S Protein of unknown function (DUF3290)
MDBPHIKD_01494 2e-28 S Protein of unknown function (DUF3290)
MDBPHIKD_01495 3.5e-42 ybaN S Protein of unknown function (DUF454)
MDBPHIKD_01496 4.2e-259 EGP Major facilitator Superfamily
MDBPHIKD_01497 4.3e-85 perR P Belongs to the Fur family
MDBPHIKD_01498 2.2e-233 cycA E Amino acid permease
MDBPHIKD_01499 2.6e-103 V VanZ like family
MDBPHIKD_01500 1e-23
MDBPHIKD_01501 2.2e-85 S Short repeat of unknown function (DUF308)
MDBPHIKD_01502 4.5e-79 S Psort location Cytoplasmic, score
MDBPHIKD_01503 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
MDBPHIKD_01504 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
MDBPHIKD_01505 1e-156 yeaE S Aldo keto
MDBPHIKD_01506 4e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
MDBPHIKD_01507 7.3e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MDBPHIKD_01508 7.6e-151 xth 3.1.11.2 L exodeoxyribonuclease III
MDBPHIKD_01509 1.9e-95 lytE M LysM domain protein
MDBPHIKD_01510 0.0 oppD EP Psort location Cytoplasmic, score
MDBPHIKD_01511 6.8e-43 lytE M LysM domain protein
MDBPHIKD_01512 1.1e-166 sufD O Uncharacterized protein family (UPF0051)
MDBPHIKD_01513 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDBPHIKD_01514 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MDBPHIKD_01515 4.2e-240 lmrB EGP Major facilitator Superfamily
MDBPHIKD_01516 1.1e-101 2.3.1.128 K Acetyltransferase (GNAT) domain
MDBPHIKD_01524 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDBPHIKD_01525 7.7e-160 endA V DNA/RNA non-specific endonuclease
MDBPHIKD_01526 3.5e-255 yifK E Amino acid permease
MDBPHIKD_01528 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDBPHIKD_01529 2e-233 N Uncharacterized conserved protein (DUF2075)
MDBPHIKD_01530 6.1e-123 S SNARE associated Golgi protein
MDBPHIKD_01531 0.0 uvrA3 L excinuclease ABC, A subunit
MDBPHIKD_01532 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDBPHIKD_01533 2.3e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDBPHIKD_01534 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDBPHIKD_01535 7.6e-149 S DUF218 domain
MDBPHIKD_01536 0.0 ubiB S ABC1 family
MDBPHIKD_01537 2.2e-246 yhdP S Transporter associated domain
MDBPHIKD_01538 5e-75 copY K Copper transport repressor CopY TcrY
MDBPHIKD_01539 2.3e-246 EGP Major facilitator Superfamily
MDBPHIKD_01540 4.5e-74 yeaL S UPF0756 membrane protein
MDBPHIKD_01541 1.7e-62 yphH S Cupin domain
MDBPHIKD_01542 2.8e-87 C Flavodoxin
MDBPHIKD_01543 2.9e-162 K LysR substrate binding domain protein
MDBPHIKD_01544 6.2e-176 1.1.1.346 C Aldo keto reductase
MDBPHIKD_01545 2.1e-39 gcvR T Belongs to the UPF0237 family
MDBPHIKD_01546 1.6e-244 XK27_08635 S UPF0210 protein
MDBPHIKD_01547 9.6e-286 S C4-dicarboxylate anaerobic carrier
MDBPHIKD_01548 6.5e-127 pgm3 3.1.3.73 G phosphoglycerate mutase family
MDBPHIKD_01549 1.3e-41
MDBPHIKD_01550 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDBPHIKD_01551 1.1e-211 gldA 1.1.1.6 C dehydrogenase
MDBPHIKD_01552 7e-126 S Alpha beta hydrolase
MDBPHIKD_01553 7.1e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDBPHIKD_01554 1.5e-103
MDBPHIKD_01556 1.4e-124 yciB M ErfK YbiS YcfS YnhG
MDBPHIKD_01557 8.8e-96 S Putative peptidoglycan binding domain
MDBPHIKD_01558 7.7e-44 S Putative peptidoglycan binding domain
MDBPHIKD_01559 9.9e-112 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MDBPHIKD_01560 2.4e-89
MDBPHIKD_01561 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
MDBPHIKD_01562 5.1e-218 yttB EGP Major facilitator Superfamily
MDBPHIKD_01563 4.3e-104
MDBPHIKD_01564 1e-24
MDBPHIKD_01565 5.5e-175 scrR K Transcriptional regulator, LacI family
MDBPHIKD_01566 2.5e-255 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDBPHIKD_01567 2.4e-50 czrA K Transcriptional regulator, ArsR family
MDBPHIKD_01568 2.1e-38
MDBPHIKD_01569 0.0 yhcA V ABC transporter, ATP-binding protein
MDBPHIKD_01570 9.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MDBPHIKD_01571 4e-174 hrtB V ABC transporter permease
MDBPHIKD_01572 1.9e-89 ygfC K transcriptional regulator (TetR family)
MDBPHIKD_01573 1.3e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
MDBPHIKD_01574 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
MDBPHIKD_01575 5.5e-36
MDBPHIKD_01576 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDBPHIKD_01578 2.7e-92 yxiO S Vacuole effluxer Atg22 like
MDBPHIKD_01579 4.9e-111 yxiO S Vacuole effluxer Atg22 like
MDBPHIKD_01580 9.2e-258 npp S type I phosphodiesterase nucleotide pyrophosphatase
MDBPHIKD_01581 1.4e-240 E amino acid
MDBPHIKD_01582 3.2e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDBPHIKD_01584 3.5e-28 WQ51_00220 K Helix-turn-helix XRE-family like proteins
MDBPHIKD_01585 4.2e-15 S Protein of unknown function (DUF3278)
MDBPHIKD_01586 4.2e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
MDBPHIKD_01587 1.6e-41 S Cytochrome B5
MDBPHIKD_01588 5.4e-09 S Cytochrome B5
MDBPHIKD_01589 1.8e-39 S Cytochrome B5
MDBPHIKD_01590 2.4e-77 elaA S Gnat family
MDBPHIKD_01591 1.4e-121 GM NmrA-like family
MDBPHIKD_01592 2.5e-52 hxlR K Transcriptional regulator, HxlR family
MDBPHIKD_01593 6.7e-110 XK27_02070 S Nitroreductase family
MDBPHIKD_01594 6.2e-84 K Transcriptional regulator, HxlR family
MDBPHIKD_01595 8.5e-243
MDBPHIKD_01596 2e-211 EGP Major facilitator Superfamily
MDBPHIKD_01597 4.7e-257 pepC 3.4.22.40 E aminopeptidase
MDBPHIKD_01598 9.6e-115 ylbE GM NAD dependent epimerase dehydratase family protein
MDBPHIKD_01599 0.0 pepN 3.4.11.2 E aminopeptidase
MDBPHIKD_01600 6.3e-94 folT S ECF transporter, substrate-specific component
MDBPHIKD_01601 1.7e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
MDBPHIKD_01602 6e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MDBPHIKD_01603 9.8e-126 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MDBPHIKD_01604 1.1e-206 2.7.7.65 T GGDEF domain
MDBPHIKD_01605 7.5e-91
MDBPHIKD_01606 4e-256 pgaC GT2 M Glycosyl transferase
MDBPHIKD_01607 1.7e-159 T EAL domain
MDBPHIKD_01615 7.7e-35
MDBPHIKD_01616 4.4e-55 S Mazg nucleotide pyrophosphohydrolase
MDBPHIKD_01617 8.8e-161 xth 3.1.11.2 L exodeoxyribonuclease III
MDBPHIKD_01618 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDBPHIKD_01619 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDBPHIKD_01620 2.1e-288 S Psort location CytoplasmicMembrane, score
MDBPHIKD_01621 1.4e-164 yueF S AI-2E family transporter
MDBPHIKD_01622 3.2e-119 S dextransucrase activity
MDBPHIKD_01624 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MDBPHIKD_01625 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDBPHIKD_01626 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDBPHIKD_01627 1.7e-125 coiA 3.6.4.12 S Competence protein
MDBPHIKD_01628 6.5e-33 coiA 3.6.4.12 S Competence protein
MDBPHIKD_01629 1.5e-269 pipD E Dipeptidase
MDBPHIKD_01630 5.1e-116 yjbH Q Thioredoxin
MDBPHIKD_01631 4e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
MDBPHIKD_01632 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDBPHIKD_01633 2.4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MDBPHIKD_01634 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDBPHIKD_01635 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDBPHIKD_01636 7.1e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MDBPHIKD_01637 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDBPHIKD_01639 1.9e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDBPHIKD_01640 7.4e-204 XK27_09615 S reductase
MDBPHIKD_01641 2.9e-102 nqr 1.5.1.36 S reductase
MDBPHIKD_01643 1.3e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDBPHIKD_01644 1.5e-183 K Transcriptional regulator, LacI family
MDBPHIKD_01645 5.5e-261 G Major Facilitator
MDBPHIKD_01646 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDBPHIKD_01647 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MDBPHIKD_01648 2.3e-267 G Major Facilitator
MDBPHIKD_01649 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MDBPHIKD_01650 0.0 M domain protein
MDBPHIKD_01651 2.7e-277 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
MDBPHIKD_01652 2e-275 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MDBPHIKD_01653 2.2e-72
MDBPHIKD_01654 1.7e-73 K Transcriptional regulator, TetR family
MDBPHIKD_01655 3.3e-13 K Transcriptional regulator, TetR family
MDBPHIKD_01656 5.5e-248 steT_1 E amino acid
MDBPHIKD_01657 6.4e-139 puuD S peptidase C26
MDBPHIKD_01658 1e-81 tlpA2 L Transposase IS200 like
MDBPHIKD_01659 4e-242 L transposase, IS605 OrfB family
MDBPHIKD_01661 2.6e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDBPHIKD_01662 7e-75
MDBPHIKD_01663 1.1e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDBPHIKD_01664 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDBPHIKD_01665 5.3e-264 nox C NADH oxidase
MDBPHIKD_01666 3e-87 hmpT S ECF-type riboflavin transporter, S component
MDBPHIKD_01667 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MDBPHIKD_01668 9.2e-169 yvgN C Aldo keto reductase
MDBPHIKD_01669 3.5e-137 puuD S peptidase C26
MDBPHIKD_01670 7.3e-85 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDBPHIKD_01671 7.6e-31 L PFAM transposase IS200-family protein
MDBPHIKD_01672 2.4e-178 L Belongs to the 'phage' integrase family
MDBPHIKD_01677 2.8e-212 fhaB M Rib/alpha-like repeat
MDBPHIKD_01678 2e-184 S Phosphotransferase system, EIIC
MDBPHIKD_01679 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDBPHIKD_01680 1.6e-183
MDBPHIKD_01681 1.2e-54 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDBPHIKD_01682 5.2e-209 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MDBPHIKD_01683 2.7e-163 K LysR substrate binding domain
MDBPHIKD_01684 1.7e-113 manA 5.3.1.8 G mannose-6-phosphate isomerase
MDBPHIKD_01685 5.2e-98 2.3.1.128 K acetyltransferase
MDBPHIKD_01686 6.2e-193
MDBPHIKD_01688 1.6e-117 plsC 2.3.1.51 I Acyltransferase
MDBPHIKD_01689 3.7e-142 yabB 2.1.1.223 L Methyltransferase small domain
MDBPHIKD_01690 5.4e-49 yazA L GIY-YIG catalytic domain protein
MDBPHIKD_01691 2e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDBPHIKD_01692 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
MDBPHIKD_01693 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDBPHIKD_01694 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MDBPHIKD_01695 7.4e-95 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDBPHIKD_01696 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
MDBPHIKD_01697 1.1e-64 yneR
MDBPHIKD_01698 1.6e-114 GM NAD(P)H-binding
MDBPHIKD_01699 2.1e-189 S membrane
MDBPHIKD_01700 1.8e-104 K Transcriptional regulator C-terminal region
MDBPHIKD_01701 2.4e-164 akr5f 1.1.1.346 S reductase
MDBPHIKD_01702 2.8e-157 K Transcriptional regulator
MDBPHIKD_01703 6.1e-185 ansA 3.5.1.1 EJ L-asparaginase, type I
MDBPHIKD_01704 1e-155 ypuA S Protein of unknown function (DUF1002)
MDBPHIKD_01705 1.1e-228 aadAT EK Aminotransferase, class I
MDBPHIKD_01706 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MDBPHIKD_01707 9.2e-155 tesE Q hydratase
MDBPHIKD_01708 4e-133 S Alpha beta hydrolase
MDBPHIKD_01710 2.6e-89 lacA S transferase hexapeptide repeat
MDBPHIKD_01711 2.1e-160 K Transcriptional regulator
MDBPHIKD_01712 1.2e-88 C Flavodoxin
MDBPHIKD_01713 6.3e-11 S Oxidoreductase, aldo keto reductase family protein
MDBPHIKD_01714 8.6e-56 yphJ 4.1.1.44 S decarboxylase
MDBPHIKD_01715 5.5e-102 M Protein of unknown function (DUF3737)
MDBPHIKD_01716 2.3e-228 4.4.1.8 E Aminotransferase, class I
MDBPHIKD_01717 4.7e-163 mleP3 S Membrane transport protein
MDBPHIKD_01718 4.4e-126 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
MDBPHIKD_01720 5.2e-148
MDBPHIKD_01721 4.8e-246 ydaM M Glycosyl transferase
MDBPHIKD_01722 6.9e-225 G Glycosyl hydrolases family 8
MDBPHIKD_01723 7.8e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MDBPHIKD_01724 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MDBPHIKD_01725 2.4e-240 ktrB P Potassium uptake protein
MDBPHIKD_01726 1.4e-116 ktrA P domain protein
MDBPHIKD_01727 2e-83 Q Methyltransferase
MDBPHIKD_01728 1.6e-233 mntH P H( )-stimulated, divalent metal cation uptake system
MDBPHIKD_01729 3e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MDBPHIKD_01730 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MDBPHIKD_01731 7.6e-97 S NADPH-dependent FMN reductase
MDBPHIKD_01732 3.6e-180 MA20_14895 S Conserved hypothetical protein 698
MDBPHIKD_01733 4.5e-137 I alpha/beta hydrolase fold
MDBPHIKD_01734 3.2e-164 lsa S ABC transporter
MDBPHIKD_01735 1.8e-101 lsa S ABC transporter
MDBPHIKD_01736 3e-181 yfeX P Peroxidase
MDBPHIKD_01737 1.5e-275 arcD S C4-dicarboxylate anaerobic carrier
MDBPHIKD_01738 6.4e-262 ytjP 3.5.1.18 E Dipeptidase
MDBPHIKD_01739 4.4e-217 uhpT EGP Major facilitator Superfamily
MDBPHIKD_01740 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MDBPHIKD_01741 1.8e-131 ponA V Beta-lactamase enzyme family
MDBPHIKD_01742 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDBPHIKD_01743 3e-75
MDBPHIKD_01744 3.1e-203 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MDBPHIKD_01745 2e-22
MDBPHIKD_01746 2e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
MDBPHIKD_01747 2.3e-300 L PFAM plasmid pRiA4b ORF-3 family protein
MDBPHIKD_01748 2.7e-207 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
MDBPHIKD_01749 7.8e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDBPHIKD_01750 2.5e-161 mleR K LysR family
MDBPHIKD_01751 2e-310 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MDBPHIKD_01752 2.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDBPHIKD_01753 5.6e-269 frdC 1.3.5.4 C FAD binding domain
MDBPHIKD_01754 1.2e-253 yflS P Sodium:sulfate symporter transmembrane region
MDBPHIKD_01755 8e-160 mleR K LysR family
MDBPHIKD_01756 9.4e-253 yjjP S Putative threonine/serine exporter
MDBPHIKD_01757 1e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
MDBPHIKD_01758 1.9e-281 emrY EGP Major facilitator Superfamily
MDBPHIKD_01759 5.3e-189 I Alpha beta
MDBPHIKD_01760 1.5e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MDBPHIKD_01761 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDBPHIKD_01763 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MDBPHIKD_01764 5.8e-124 S Domain of unknown function (DUF4811)
MDBPHIKD_01765 7.2e-270 lmrB EGP Major facilitator Superfamily
MDBPHIKD_01766 2.6e-74 merR K MerR HTH family regulatory protein
MDBPHIKD_01767 2.9e-57
MDBPHIKD_01768 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDBPHIKD_01769 8.3e-221 S CAAX protease self-immunity
MDBPHIKD_01770 3.6e-109 glnP P ABC transporter permease
MDBPHIKD_01771 2.4e-110 gluC P ABC transporter permease
MDBPHIKD_01772 1.5e-152 glnH ET ABC transporter
MDBPHIKD_01773 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDBPHIKD_01774 2.7e-82 usp1 T Belongs to the universal stress protein A family
MDBPHIKD_01775 1.3e-109 S VIT family
MDBPHIKD_01776 7.7e-118 S membrane
MDBPHIKD_01777 5.9e-166 czcD P cation diffusion facilitator family transporter
MDBPHIKD_01778 4.8e-125 sirR K iron dependent repressor
MDBPHIKD_01779 3.5e-31 cspC K Cold shock protein
MDBPHIKD_01780 2.1e-132 thrE S Putative threonine/serine exporter
MDBPHIKD_01781 7.2e-83 S Threonine/Serine exporter, ThrE
MDBPHIKD_01782 2.7e-120 lssY 3.6.1.27 I phosphatase
MDBPHIKD_01783 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
MDBPHIKD_01784 1.3e-276 lysP E amino acid
MDBPHIKD_01785 5.6e-39 L PFAM Integrase catalytic region
MDBPHIKD_01786 1.6e-134 K Transcriptional regulatory protein, C-terminal domain protein
MDBPHIKD_01787 4.6e-160 pstS P Phosphate
MDBPHIKD_01788 1.1e-153 pstC P probably responsible for the translocation of the substrate across the membrane
MDBPHIKD_01789 2.6e-155 pstA P Phosphate transport system permease protein PstA
MDBPHIKD_01790 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDBPHIKD_01791 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
MDBPHIKD_01792 2.9e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
MDBPHIKD_01793 2.8e-159 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDBPHIKD_01794 5.4e-239 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDBPHIKD_01795 1.8e-30 S Protein of unknown function (DUF2929)
MDBPHIKD_01796 0.0 dnaE 2.7.7.7 L DNA polymerase
MDBPHIKD_01797 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MDBPHIKD_01798 1.6e-168 cvfB S S1 domain
MDBPHIKD_01799 5.7e-166 xerD D recombinase XerD
MDBPHIKD_01800 1.1e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDBPHIKD_01801 1.9e-141 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDBPHIKD_01802 1.2e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDBPHIKD_01803 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDBPHIKD_01804 4.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDBPHIKD_01805 8e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
MDBPHIKD_01806 1e-273 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MDBPHIKD_01807 2.5e-13 M Lysin motif
MDBPHIKD_01808 6.9e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MDBPHIKD_01809 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MDBPHIKD_01810 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MDBPHIKD_01811 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDBPHIKD_01812 3.9e-237 S Tetratricopeptide repeat protein
MDBPHIKD_01813 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDBPHIKD_01814 0.0 yfmR S ABC transporter, ATP-binding protein
MDBPHIKD_01815 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDBPHIKD_01816 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDBPHIKD_01817 5.3e-113 hlyIII S protein, hemolysin III
MDBPHIKD_01818 8.1e-154 DegV S EDD domain protein, DegV family
MDBPHIKD_01819 3.3e-172 ypmR E lipolytic protein G-D-S-L family
MDBPHIKD_01820 7.4e-109 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MDBPHIKD_01821 1.2e-35 yozE S Belongs to the UPF0346 family
MDBPHIKD_01822 8.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDBPHIKD_01823 1.2e-143 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDBPHIKD_01824 3.1e-164 dprA LU DNA protecting protein DprA
MDBPHIKD_01825 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDBPHIKD_01826 1.2e-171 lacX 5.1.3.3 G Aldose 1-epimerase
MDBPHIKD_01827 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDBPHIKD_01828 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDBPHIKD_01829 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDBPHIKD_01830 8.9e-86 F NUDIX domain
MDBPHIKD_01831 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
MDBPHIKD_01832 5.6e-255 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDBPHIKD_01833 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDBPHIKD_01834 2.7e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
MDBPHIKD_01835 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDBPHIKD_01837 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDBPHIKD_01838 7.9e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDBPHIKD_01839 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
MDBPHIKD_01840 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
MDBPHIKD_01841 2.1e-243 codA 3.5.4.1 F cytosine deaminase
MDBPHIKD_01842 3.1e-147 tesE Q hydratase
MDBPHIKD_01843 3.6e-114 S (CBS) domain
MDBPHIKD_01844 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDBPHIKD_01845 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDBPHIKD_01846 1.6e-39 yabO J S4 domain protein
MDBPHIKD_01847 2.3e-57 divIC D Septum formation initiator
MDBPHIKD_01848 8.3e-66 yabR J RNA binding
MDBPHIKD_01849 4.3e-269 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDBPHIKD_01850 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDBPHIKD_01851 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDBPHIKD_01852 3.6e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDBPHIKD_01853 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDBPHIKD_01854 4.2e-294 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MDBPHIKD_01855 1.7e-88
MDBPHIKD_01856 2.2e-182 S YSIRK type signal peptide
MDBPHIKD_01857 2.8e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDBPHIKD_01858 1.7e-221 ecsB U ABC transporter
MDBPHIKD_01859 1.2e-137 ecsA V ABC transporter, ATP-binding protein
MDBPHIKD_01860 8.3e-78 hit FG histidine triad
MDBPHIKD_01862 1.2e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDBPHIKD_01863 0.0 L AAA domain
MDBPHIKD_01864 1.3e-229 yhaO L Ser Thr phosphatase family protein
MDBPHIKD_01865 2.6e-40 yheA S Belongs to the UPF0342 family
MDBPHIKD_01866 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MDBPHIKD_01867 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MDBPHIKD_01868 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDBPHIKD_01869 8.4e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDBPHIKD_01871 3.3e-40
MDBPHIKD_01872 1e-43
MDBPHIKD_01873 4.2e-217 folP 2.5.1.15 H dihydropteroate synthase
MDBPHIKD_01874 2.6e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
MDBPHIKD_01875 6.7e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MDBPHIKD_01876 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
MDBPHIKD_01877 1.2e-94 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MDBPHIKD_01878 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MDBPHIKD_01879 8.7e-74
MDBPHIKD_01881 1.9e-43
MDBPHIKD_01882 2.8e-120 S CAAX protease self-immunity
MDBPHIKD_01883 2.1e-32
MDBPHIKD_01884 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDBPHIKD_01885 4.6e-188 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
MDBPHIKD_01886 5.9e-114
MDBPHIKD_01887 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
MDBPHIKD_01888 3.2e-189 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDBPHIKD_01889 1.9e-86 uspA T Belongs to the universal stress protein A family
MDBPHIKD_01890 3.3e-277 pepV 3.5.1.18 E dipeptidase PepV
MDBPHIKD_01891 1.2e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDBPHIKD_01892 6.4e-304 ytgP S Polysaccharide biosynthesis protein
MDBPHIKD_01893 4.5e-42
MDBPHIKD_01894 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDBPHIKD_01895 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDBPHIKD_01896 2.5e-100 tag 3.2.2.20 L glycosylase
MDBPHIKD_01897 1.1e-235 pbuG S permease
MDBPHIKD_01898 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDBPHIKD_01899 9e-253 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDBPHIKD_01900 7e-217 iscS2 2.8.1.7 E Aminotransferase class V
MDBPHIKD_01901 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDBPHIKD_01902 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDBPHIKD_01903 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
MDBPHIKD_01904 3.3e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MDBPHIKD_01905 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MDBPHIKD_01906 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MDBPHIKD_01907 4.8e-232 ndh 1.6.99.3 C NADH dehydrogenase
MDBPHIKD_01908 9.4e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MDBPHIKD_01909 1.2e-122 radC L DNA repair protein
MDBPHIKD_01910 1.7e-179 mreB D cell shape determining protein MreB
MDBPHIKD_01911 5.9e-152 mreC M Involved in formation and maintenance of cell shape
MDBPHIKD_01912 8.7e-93 mreD M rod shape-determining protein MreD
MDBPHIKD_01913 3.2e-102 glnP P ABC transporter permease
MDBPHIKD_01914 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDBPHIKD_01915 1.5e-160 aatB ET ABC transporter substrate-binding protein
MDBPHIKD_01916 4.2e-231 ymfF S Peptidase M16 inactive domain protein
MDBPHIKD_01917 2.4e-250 ymfH S Peptidase M16
MDBPHIKD_01918 2.5e-141 ymfM S Helix-turn-helix domain
MDBPHIKD_01919 7.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDBPHIKD_01920 3.4e-233 cinA 3.5.1.42 S Belongs to the CinA family
MDBPHIKD_01921 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDBPHIKD_01922 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
MDBPHIKD_01923 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDBPHIKD_01924 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDBPHIKD_01925 1.8e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDBPHIKD_01926 1.2e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDBPHIKD_01927 2.2e-204 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDBPHIKD_01928 1.5e-29 yajC U Preprotein translocase
MDBPHIKD_01929 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MDBPHIKD_01930 1.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDBPHIKD_01931 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDBPHIKD_01932 4.1e-43 yrzL S Belongs to the UPF0297 family
MDBPHIKD_01933 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDBPHIKD_01934 6.1e-48 yrzB S Belongs to the UPF0473 family
MDBPHIKD_01935 1.6e-86 cvpA S Colicin V production protein
MDBPHIKD_01936 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDBPHIKD_01937 6.1e-54 trxA O Belongs to the thioredoxin family
MDBPHIKD_01938 4.1e-98 yslB S Protein of unknown function (DUF2507)
MDBPHIKD_01939 1.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MDBPHIKD_01940 1.8e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDBPHIKD_01941 2.1e-96 S Phosphoesterase
MDBPHIKD_01942 2.7e-76 ykuL S (CBS) domain
MDBPHIKD_01943 1.2e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
MDBPHIKD_01944 2.1e-149 ykuT M mechanosensitive ion channel
MDBPHIKD_01945 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDBPHIKD_01946 1.8e-14
MDBPHIKD_01947 1.2e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDBPHIKD_01948 4.5e-183 ccpA K catabolite control protein A
MDBPHIKD_01949 1.8e-137
MDBPHIKD_01950 3.5e-132 yebC K Transcriptional regulatory protein
MDBPHIKD_01951 7.9e-185 comGA NU Type II IV secretion system protein
MDBPHIKD_01952 2.3e-187 comGB NU type II secretion system
MDBPHIKD_01953 7.1e-47 comGC U competence protein ComGC
MDBPHIKD_01954 2.6e-79 NU general secretion pathway protein
MDBPHIKD_01955 4.8e-45
MDBPHIKD_01956 3.6e-73
MDBPHIKD_01958 5.9e-146 ytxK 2.1.1.72 L N-6 DNA Methylase
MDBPHIKD_01959 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDBPHIKD_01960 8.8e-118 S Calcineurin-like phosphoesterase
MDBPHIKD_01961 4.4e-100 yutD S Protein of unknown function (DUF1027)
MDBPHIKD_01962 2.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDBPHIKD_01963 2.8e-114 S Protein of unknown function (DUF1461)
MDBPHIKD_01964 5.5e-110 dedA S SNARE-like domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)