ORF_ID e_value Gene_name EC_number CAZy COGs Description
ICLLHFKM_00001 5.4e-217
ICLLHFKM_00002 3e-156 S Phage tail protein
ICLLHFKM_00003 0.0 M Phage tail tape measure protein TP901
ICLLHFKM_00004 1.5e-19
ICLLHFKM_00005 7.9e-23
ICLLHFKM_00006 2.2e-116
ICLLHFKM_00007 4e-77
ICLLHFKM_00008 3.2e-62 S Bacteriophage HK97-gp10, putative tail-component
ICLLHFKM_00009 3.9e-40 S Phage head-tail joining protein
ICLLHFKM_00010 2e-68 S Phage gp6-like head-tail connector protein
ICLLHFKM_00011 7e-209 S Phage capsid family
ICLLHFKM_00012 4.9e-114 pi136 S Caudovirus prohead serine protease
ICLLHFKM_00013 5.5e-239 S Phage portal protein
ICLLHFKM_00015 0.0 terL S overlaps another CDS with the same product name
ICLLHFKM_00016 3.4e-77 terS L Phage terminase, small subunit
ICLLHFKM_00017 4.6e-151 L HNH nucleases
ICLLHFKM_00018 2e-172 bcgIA 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
ICLLHFKM_00019 2.6e-86 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
ICLLHFKM_00020 1.2e-82 arpU S Phage transcriptional regulator, ArpU family
ICLLHFKM_00027 4.5e-124
ICLLHFKM_00028 6.4e-67
ICLLHFKM_00030 2.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
ICLLHFKM_00031 2.8e-190 L Belongs to the 'phage' integrase family
ICLLHFKM_00032 1.5e-113 L DnaD domain protein
ICLLHFKM_00035 8e-15
ICLLHFKM_00036 7.6e-58
ICLLHFKM_00037 1.2e-35
ICLLHFKM_00039 1.1e-09 K Helix-turn-helix XRE-family like proteins
ICLLHFKM_00040 1.4e-121 3.4.21.88 K Peptidase S24-like
ICLLHFKM_00042 1.5e-15
ICLLHFKM_00045 3.2e-17
ICLLHFKM_00047 4.5e-136 L Belongs to the 'phage' integrase family
ICLLHFKM_00049 2.3e-36 S Lipopolysaccharide assembly protein A domain
ICLLHFKM_00050 3.7e-159 3.1.3.102, 3.1.3.104 S hydrolase
ICLLHFKM_00051 1.2e-90 ntd 2.4.2.6 F Nucleoside
ICLLHFKM_00052 7.5e-21
ICLLHFKM_00053 1.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
ICLLHFKM_00054 4.3e-115 yviA S Protein of unknown function (DUF421)
ICLLHFKM_00055 1.9e-29 S Protein of unknown function (DUF3290)
ICLLHFKM_00056 2e-28 S Protein of unknown function (DUF3290)
ICLLHFKM_00057 3.5e-42 ybaN S Protein of unknown function (DUF454)
ICLLHFKM_00058 7.7e-44 S Putative peptidoglycan binding domain
ICLLHFKM_00059 4.5e-238 L Integrase core domain
ICLLHFKM_00060 1.2e-132 O Bacterial dnaA protein
ICLLHFKM_00061 9.2e-45 S Putative peptidoglycan binding domain
ICLLHFKM_00062 3.8e-23 ybl78 L Replication initiation and membrane attachment
ICLLHFKM_00063 3.6e-67 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
ICLLHFKM_00064 1.1e-79 recT L RecT family
ICLLHFKM_00068 1.6e-13 K Cro/C1-type HTH DNA-binding domain
ICLLHFKM_00069 9.7e-12 S Domain of unknown function (DUF1508)
ICLLHFKM_00071 1.2e-26 S Domain of unknown function (DUF771)
ICLLHFKM_00072 1.1e-69 ps308 K AntA/AntB antirepressor
ICLLHFKM_00073 1.4e-12 K BRO family, N-terminal domain
ICLLHFKM_00076 1.7e-85 3.1.21.3 V Type I restriction modification DNA specificity domain
ICLLHFKM_00077 7e-254 hsdM 2.1.1.72 V type I restriction-modification system
ICLLHFKM_00078 1.9e-301 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
ICLLHFKM_00080 1.2e-182 M lysozyme activity
ICLLHFKM_00081 2.3e-75 S Bacteriophage holin family
ICLLHFKM_00083 2.9e-19 gepA S Protein of unknown function (DUF4065)
ICLLHFKM_00084 1e-13 E Domain of unknown function (DUF2479)
ICLLHFKM_00085 4.1e-198 2.7.7.65 T GGDEF domain
ICLLHFKM_00086 5.6e-101 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
ICLLHFKM_00087 4.1e-56 L Transposase
ICLLHFKM_00088 2.2e-222 cycA E Amino acid permease
ICLLHFKM_00089 8.5e-139 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICLLHFKM_00090 3e-265 glnP P ABC transporter
ICLLHFKM_00091 4.1e-56 L Transposase
ICLLHFKM_00092 1.7e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
ICLLHFKM_00093 2e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICLLHFKM_00094 1.9e-127 L Helix-turn-helix domain
ICLLHFKM_00095 3.2e-121 L hmm pf00665
ICLLHFKM_00096 0.0 pacL 3.6.3.8 P P-type ATPase
ICLLHFKM_00097 9.9e-85 dps P Belongs to the Dps family
ICLLHFKM_00098 2.1e-255 yagE E amino acid
ICLLHFKM_00099 3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
ICLLHFKM_00100 1e-13 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ICLLHFKM_00101 1.9e-127 L Helix-turn-helix domain
ICLLHFKM_00102 3.2e-121 L hmm pf00665
ICLLHFKM_00103 5.2e-198 K helix_turn_helix, arabinose operon control protein
ICLLHFKM_00104 6.2e-42 pduA_4 CQ BMC
ICLLHFKM_00105 2.7e-134 pduB E BMC
ICLLHFKM_00106 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
ICLLHFKM_00107 1.1e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
ICLLHFKM_00108 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
ICLLHFKM_00109 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
ICLLHFKM_00110 6.5e-60 pduH S Dehydratase medium subunit
ICLLHFKM_00111 2.1e-73 pduK CQ BMC
ICLLHFKM_00112 7.6e-43 pduA_4 CQ BMC
ICLLHFKM_00113 2.1e-117 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
ICLLHFKM_00114 1.1e-89 S Putative propanediol utilisation
ICLLHFKM_00115 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
ICLLHFKM_00116 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
ICLLHFKM_00117 7.4e-80 pduO S Haem-degrading
ICLLHFKM_00118 3.4e-269 pduP 1.2.1.87 C Aldehyde dehydrogenase family
ICLLHFKM_00119 2.4e-209 pduQ C Iron-containing alcohol dehydrogenase
ICLLHFKM_00120 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICLLHFKM_00121 5.5e-56 pduU E BMC
ICLLHFKM_00122 1.4e-147 3.1.3.48 T Pfam:Y_phosphatase3C
ICLLHFKM_00123 1.3e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
ICLLHFKM_00124 6.7e-80 P Cadmium resistance transporter
ICLLHFKM_00125 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
ICLLHFKM_00126 3.9e-78 fld C Flavodoxin
ICLLHFKM_00127 1.5e-155 XK27_04590 S NADPH-dependent FMN reductase
ICLLHFKM_00128 8.2e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
ICLLHFKM_00129 2.1e-207 cobD 4.1.1.81 E Aminotransferase class I and II
ICLLHFKM_00130 4.1e-264 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
ICLLHFKM_00131 5.7e-180 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ICLLHFKM_00132 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
ICLLHFKM_00133 3.5e-208 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ICLLHFKM_00134 3.3e-109 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ICLLHFKM_00135 5.1e-96 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
ICLLHFKM_00136 7.6e-135 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ICLLHFKM_00137 5.5e-192 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
ICLLHFKM_00138 1.3e-131 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ICLLHFKM_00139 6.4e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
ICLLHFKM_00140 1.1e-259 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ICLLHFKM_00141 4.4e-146 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
ICLLHFKM_00142 3.9e-125 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ICLLHFKM_00143 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
ICLLHFKM_00144 1.9e-52 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
ICLLHFKM_00145 5.4e-116 cbiQ P Cobalt transport protein
ICLLHFKM_00146 6.3e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
ICLLHFKM_00147 2.2e-274 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
ICLLHFKM_00148 7.9e-79 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
ICLLHFKM_00149 1.8e-229 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ICLLHFKM_00150 6.5e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
ICLLHFKM_00151 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
ICLLHFKM_00152 9.3e-250 hemL 5.4.3.8 H Aminotransferase class-III
ICLLHFKM_00153 3e-102 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
ICLLHFKM_00154 9.9e-135 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ICLLHFKM_00155 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
ICLLHFKM_00156 5.3e-130 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
ICLLHFKM_00157 6.5e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
ICLLHFKM_00158 9.6e-62 S Domain of unknown function (DUF4430)
ICLLHFKM_00159 1.2e-81 S ECF transporter, substrate-specific component
ICLLHFKM_00160 1.3e-188 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICLLHFKM_00161 1.1e-309 lmrA V ABC transporter, ATP-binding protein
ICLLHFKM_00162 0.0 yfiC V ABC transporter
ICLLHFKM_00163 7.5e-285 pipD E Dipeptidase
ICLLHFKM_00164 6.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICLLHFKM_00165 3.4e-132 gntR K UbiC transcription regulator-associated domain protein
ICLLHFKM_00166 7.3e-126 I transferase activity, transferring acyl groups other than amino-acyl groups
ICLLHFKM_00167 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
ICLLHFKM_00168 1.1e-242 yagE E amino acid
ICLLHFKM_00169 1.3e-139 aroD S Serine hydrolase (FSH1)
ICLLHFKM_00170 1.1e-240 brnQ U Component of the transport system for branched-chain amino acids
ICLLHFKM_00171 1.2e-114 GK ROK family
ICLLHFKM_00172 7e-39 GK ROK family
ICLLHFKM_00173 0.0 tetP J elongation factor G
ICLLHFKM_00174 5.1e-81 uspA T universal stress protein
ICLLHFKM_00175 8.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
ICLLHFKM_00176 7.1e-63
ICLLHFKM_00177 5.2e-14
ICLLHFKM_00178 3.3e-108
ICLLHFKM_00179 2e-134 V ABC transporter
ICLLHFKM_00180 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_00181 8.9e-147 recO L Involved in DNA repair and RecF pathway recombination
ICLLHFKM_00182 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICLLHFKM_00183 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ICLLHFKM_00184 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICLLHFKM_00185 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
ICLLHFKM_00186 4.6e-177 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ICLLHFKM_00187 1.5e-90 bioY S BioY family
ICLLHFKM_00188 4.2e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
ICLLHFKM_00189 6.1e-50 M KxYKxGKxW signal domain protein
ICLLHFKM_00190 4.2e-36
ICLLHFKM_00191 5.2e-33 S Psort location CytoplasmicMembrane, score
ICLLHFKM_00192 1.5e-42 S Psort location CytoplasmicMembrane, score
ICLLHFKM_00193 2.8e-82 M biosynthesis protein
ICLLHFKM_00194 2.3e-186 cps3F
ICLLHFKM_00195 6.2e-103 S enterobacterial common antigen metabolic process
ICLLHFKM_00197 2.4e-103 acmD M repeat protein
ICLLHFKM_00198 1.8e-131 M transferase activity, transferring glycosyl groups
ICLLHFKM_00199 8.8e-150 waaB GT4 M Glycosyl transferases group 1
ICLLHFKM_00200 3.6e-239 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
ICLLHFKM_00201 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_00202 1.7e-51 L Transposase IS66 family
ICLLHFKM_00204 2.8e-19
ICLLHFKM_00205 9.2e-40
ICLLHFKM_00206 0.0 ydaO E amino acid
ICLLHFKM_00207 4.3e-305 ybeC E amino acid
ICLLHFKM_00208 4.2e-86 S Aminoacyl-tRNA editing domain
ICLLHFKM_00209 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ICLLHFKM_00210 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICLLHFKM_00212 6.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ICLLHFKM_00213 0.0 uup S ABC transporter, ATP-binding protein
ICLLHFKM_00214 6e-185 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICLLHFKM_00215 4.3e-230 mtnE 2.6.1.83 E Aminotransferase
ICLLHFKM_00216 3.6e-148 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
ICLLHFKM_00217 1.4e-139 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICLLHFKM_00218 3.9e-229 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICLLHFKM_00219 2.9e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICLLHFKM_00220 1.9e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICLLHFKM_00221 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
ICLLHFKM_00222 1.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
ICLLHFKM_00223 1.5e-32 L PFAM Integrase catalytic region
ICLLHFKM_00224 1.2e-213 L PFAM Integrase catalytic region
ICLLHFKM_00230 5.7e-207 XK27_11280 S Psort location CytoplasmicMembrane, score
ICLLHFKM_00231 0.0
ICLLHFKM_00233 7.1e-74 S Transcriptional regulator, RinA family
ICLLHFKM_00238 4.4e-129 dck 2.7.1.74 F deoxynucleoside kinase
ICLLHFKM_00239 2e-160
ICLLHFKM_00245 1.1e-87
ICLLHFKM_00246 6.9e-20
ICLLHFKM_00250 5.2e-16
ICLLHFKM_00254 9.8e-74 rusA L Endodeoxyribonuclease RusA
ICLLHFKM_00255 1.4e-32
ICLLHFKM_00256 2e-34
ICLLHFKM_00258 2.1e-18
ICLLHFKM_00263 1.1e-24 ybl78 L DnaD domain protein
ICLLHFKM_00264 7.3e-129 S Putative HNHc nuclease
ICLLHFKM_00265 1.2e-54 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICLLHFKM_00267 3.8e-07
ICLLHFKM_00270 1e-07
ICLLHFKM_00274 8e-126 S Protein of unknown function (DUF3102)
ICLLHFKM_00275 1.3e-20
ICLLHFKM_00278 1.8e-48 K addiction module antidote protein HigA
ICLLHFKM_00279 6.8e-75 E IrrE N-terminal-like domain
ICLLHFKM_00284 4.6e-70 L Belongs to the 'phage' integrase family
ICLLHFKM_00285 6.5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ICLLHFKM_00286 6.5e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICLLHFKM_00287 9e-139 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICLLHFKM_00288 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICLLHFKM_00289 5.7e-166 xerD D recombinase XerD
ICLLHFKM_00290 9.3e-169 cvfB S S1 domain
ICLLHFKM_00291 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ICLLHFKM_00292 0.0 dnaE 2.7.7.7 L DNA polymerase
ICLLHFKM_00293 2.3e-30 S Protein of unknown function (DUF2929)
ICLLHFKM_00294 4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ICLLHFKM_00295 1.2e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICLLHFKM_00296 3.8e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
ICLLHFKM_00297 4.8e-221 patA 2.6.1.1 E Aminotransferase
ICLLHFKM_00298 1.2e-213 L PFAM Integrase catalytic region
ICLLHFKM_00299 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ICLLHFKM_00300 2.5e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICLLHFKM_00301 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ICLLHFKM_00302 1e-284 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICLLHFKM_00303 2.8e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
ICLLHFKM_00304 1.4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICLLHFKM_00305 1.7e-57 yabA L Involved in initiation control of chromosome replication
ICLLHFKM_00306 8.2e-185 holB 2.7.7.7 L DNA polymerase III
ICLLHFKM_00307 7.6e-52 yaaQ S Cyclic-di-AMP receptor
ICLLHFKM_00308 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICLLHFKM_00309 9.7e-39 S Protein of unknown function (DUF2508)
ICLLHFKM_00310 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICLLHFKM_00311 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICLLHFKM_00312 4.9e-281 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICLLHFKM_00313 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ICLLHFKM_00314 3.4e-35 nrdH O Glutaredoxin
ICLLHFKM_00315 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICLLHFKM_00316 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICLLHFKM_00317 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
ICLLHFKM_00318 8.3e-134 S Putative adhesin
ICLLHFKM_00319 5.6e-80 XK27_06920 S Protein of unknown function (DUF1700)
ICLLHFKM_00320 2.4e-56 K transcriptional regulator PadR family
ICLLHFKM_00321 5.5e-185 L transposase, IS605 OrfB family
ICLLHFKM_00322 4.2e-51 L Transposase IS200 like
ICLLHFKM_00323 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICLLHFKM_00324 1.3e-164 T Calcineurin-like phosphoesterase superfamily domain
ICLLHFKM_00325 1.8e-223 mdtG EGP Major facilitator Superfamily
ICLLHFKM_00326 3.4e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ICLLHFKM_00327 5.7e-55 yxjG_1 E methionine synthase, vitamin-B12 independent
ICLLHFKM_00328 2e-120 yxjG_1 E methionine synthase, vitamin-B12 independent
ICLLHFKM_00329 5.8e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
ICLLHFKM_00330 1.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICLLHFKM_00331 0.0 lacZ 3.2.1.23 G -beta-galactosidase
ICLLHFKM_00332 0.0 lacS G Transporter
ICLLHFKM_00333 6.5e-190 lacR K Transcriptional regulator
ICLLHFKM_00334 5e-84
ICLLHFKM_00335 4.2e-51 L Transposase IS200 like
ICLLHFKM_00336 5.5e-185 L transposase, IS605 OrfB family
ICLLHFKM_00338 4.2e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
ICLLHFKM_00339 9.7e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
ICLLHFKM_00340 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
ICLLHFKM_00341 0.0 trxB2 1.8.1.9 C Thioredoxin domain
ICLLHFKM_00342 4e-40 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
ICLLHFKM_00343 2e-149 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
ICLLHFKM_00344 1.1e-272 pipD E Dipeptidase
ICLLHFKM_00345 0.0 yjbQ P TrkA C-terminal domain protein
ICLLHFKM_00346 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
ICLLHFKM_00347 4.6e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICLLHFKM_00348 2.4e-89
ICLLHFKM_00349 8.1e-35
ICLLHFKM_00350 1.6e-09 K Transcriptional regulator, HxlR family
ICLLHFKM_00351 3.8e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICLLHFKM_00352 2.5e-142 epsB M biosynthesis protein
ICLLHFKM_00353 6.9e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
ICLLHFKM_00354 1e-103 rfbP M Bacterial sugar transferase
ICLLHFKM_00355 3e-78 fcbD 2.7.8.12 GT2 M Glycosyltransferase like family 2
ICLLHFKM_00356 2.9e-67 S Bacterial transferase hexapeptide (six repeats)
ICLLHFKM_00357 2.2e-64 cps3F
ICLLHFKM_00358 1.3e-119 S Membrane protein involved in the export of O-antigen and teichoic acid
ICLLHFKM_00359 1.3e-31 M Glycosyltransferase like family 2
ICLLHFKM_00360 4.5e-34 pssD M Oligosaccharide biosynthesis protein Alg14 like
ICLLHFKM_00361 1.7e-34 pssE S Glycosyltransferase family 28 C-terminal domain
ICLLHFKM_00362 1.2e-99 M Glycosyltransferase
ICLLHFKM_00363 7.7e-88 GT4 M Glycosyltransferase, group 1 family protein
ICLLHFKM_00364 4.2e-51 L Transposase IS200 like
ICLLHFKM_00365 5.5e-185 L transposase, IS605 OrfB family
ICLLHFKM_00366 2.3e-75 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICLLHFKM_00367 3.1e-161 gspA M family 8
ICLLHFKM_00368 3.4e-160 S Alpha beta hydrolase
ICLLHFKM_00369 4.8e-96 K Acetyltransferase (GNAT) domain
ICLLHFKM_00370 1.6e-41 S Cytochrome B5
ICLLHFKM_00371 5.4e-09 S Cytochrome B5
ICLLHFKM_00372 1.8e-39 S Cytochrome B5
ICLLHFKM_00373 2.4e-77 elaA S Gnat family
ICLLHFKM_00374 1.4e-121 GM NmrA-like family
ICLLHFKM_00375 2.5e-52 hxlR K Transcriptional regulator, HxlR family
ICLLHFKM_00376 3.3e-109 XK27_02070 S Nitroreductase family
ICLLHFKM_00377 1.4e-83 K Transcriptional regulator, HxlR family
ICLLHFKM_00378 1e-154
ICLLHFKM_00379 6.5e-60
ICLLHFKM_00380 2.2e-210 EGP Major facilitator Superfamily
ICLLHFKM_00381 4e-256 pepC 3.4.22.40 E aminopeptidase
ICLLHFKM_00382 9.9e-112 ylbE GM NAD dependent epimerase dehydratase family protein
ICLLHFKM_00383 0.0 pepN 3.4.11.2 E aminopeptidase
ICLLHFKM_00384 2.2e-229 L transposase, IS605 OrfB family
ICLLHFKM_00385 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ICLLHFKM_00386 1.5e-147 eutJ E Hsp70 protein
ICLLHFKM_00387 1.9e-127 L Helix-turn-helix domain
ICLLHFKM_00388 3.2e-121 L hmm pf00665
ICLLHFKM_00389 9.3e-65 gntR1 K Transcriptional regulator, GntR family
ICLLHFKM_00390 8e-157 V ABC transporter, ATP-binding protein
ICLLHFKM_00391 2.6e-118
ICLLHFKM_00392 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
ICLLHFKM_00393 1.7e-100 S Pfam:DUF3816
ICLLHFKM_00394 0.0 clpE O Belongs to the ClpA ClpB family
ICLLHFKM_00395 2.2e-27
ICLLHFKM_00396 2.7e-39 ptsH G phosphocarrier protein HPR
ICLLHFKM_00397 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICLLHFKM_00398 1.4e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
ICLLHFKM_00399 1.3e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
ICLLHFKM_00400 2.8e-177 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICLLHFKM_00401 3.3e-39 ykuJ S Protein of unknown function (DUF1797)
ICLLHFKM_00402 4.6e-52 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
ICLLHFKM_00403 9.5e-101 G MFS/sugar transport protein
ICLLHFKM_00404 2.9e-154 EG EamA-like transporter family
ICLLHFKM_00405 2.5e-118 L Integrase
ICLLHFKM_00406 1.7e-159 rssA S Phospholipase, patatin family
ICLLHFKM_00407 1.2e-213 L PFAM Integrase catalytic region
ICLLHFKM_00408 1.1e-161 K LysR substrate binding domain protein
ICLLHFKM_00409 2.8e-87 C Flavodoxin
ICLLHFKM_00410 3.9e-80 yphH S Cupin domain
ICLLHFKM_00411 2.6e-43 yeaL S UPF0756 membrane protein
ICLLHFKM_00412 3.3e-245 EGP Major facilitator Superfamily
ICLLHFKM_00413 5e-75 copY K Copper transport repressor CopY TcrY
ICLLHFKM_00414 2.2e-246 yhdP S Transporter associated domain
ICLLHFKM_00415 0.0 ubiB S ABC1 family
ICLLHFKM_00416 9.9e-149 S DUF218 domain
ICLLHFKM_00417 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICLLHFKM_00418 2.3e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICLLHFKM_00419 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICLLHFKM_00420 0.0 uvrA3 L excinuclease ABC, A subunit
ICLLHFKM_00421 6.1e-123 S SNARE associated Golgi protein
ICLLHFKM_00422 2.4e-220 N Uncharacterized conserved protein (DUF2075)
ICLLHFKM_00423 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ICLLHFKM_00425 3.5e-255 yifK E Amino acid permease
ICLLHFKM_00426 7.7e-160 endA V DNA/RNA non-specific endonuclease
ICLLHFKM_00427 6.3e-13 K Transcriptional regulator
ICLLHFKM_00428 1.3e-56 sip L Belongs to the 'phage' integrase family
ICLLHFKM_00434 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
ICLLHFKM_00435 5e-276 lysP E amino acid
ICLLHFKM_00436 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
ICLLHFKM_00437 6.1e-120 lssY 3.6.1.27 I phosphatase
ICLLHFKM_00438 7.2e-83 S Threonine/Serine exporter, ThrE
ICLLHFKM_00439 2.1e-132 thrE S Putative threonine/serine exporter
ICLLHFKM_00440 3.5e-31 cspC K Cold shock protein
ICLLHFKM_00441 4.8e-125 sirR K iron dependent repressor
ICLLHFKM_00442 5e-165 czcD P cation diffusion facilitator family transporter
ICLLHFKM_00443 1e-117 S membrane
ICLLHFKM_00444 1.3e-109 S VIT family
ICLLHFKM_00445 2.7e-82 usp1 T Belongs to the universal stress protein A family
ICLLHFKM_00446 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICLLHFKM_00447 5.7e-152 glnH ET ABC transporter
ICLLHFKM_00448 1.6e-109 gluC P ABC transporter permease
ICLLHFKM_00449 5.2e-108 glnP P ABC transporter permease
ICLLHFKM_00450 5.9e-219 S CAAX protease self-immunity
ICLLHFKM_00451 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICLLHFKM_00452 2.9e-57
ICLLHFKM_00453 2.6e-74 merR K MerR HTH family regulatory protein
ICLLHFKM_00454 7.2e-270 lmrB EGP Major facilitator Superfamily
ICLLHFKM_00455 5.8e-124 S Domain of unknown function (DUF4811)
ICLLHFKM_00456 4e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
ICLLHFKM_00458 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICLLHFKM_00459 8.7e-36 UW LPXTG-motif cell wall anchor domain protein
ICLLHFKM_00460 1.4e-40 K Transcriptional regulator, TetR family
ICLLHFKM_00461 1.5e-43 S Fic/DOC family
ICLLHFKM_00462 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICLLHFKM_00463 1.3e-51 S Iron-sulfur cluster assembly protein
ICLLHFKM_00464 2.7e-152
ICLLHFKM_00465 1.7e-177
ICLLHFKM_00466 6.5e-90 dut S Protein conserved in bacteria
ICLLHFKM_00469 2.6e-112 K Transcriptional regulator
ICLLHFKM_00470 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
ICLLHFKM_00471 7.4e-55 ysxB J Cysteine protease Prp
ICLLHFKM_00472 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ICLLHFKM_00473 1.2e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ICLLHFKM_00474 3.2e-203 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICLLHFKM_00475 4.5e-123 J 2'-5' RNA ligase superfamily
ICLLHFKM_00476 2.2e-70 yqhY S Asp23 family, cell envelope-related function
ICLLHFKM_00477 3.6e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICLLHFKM_00478 3.2e-38 UW LPXTG-motif cell wall anchor domain protein
ICLLHFKM_00479 5.1e-77 L Transposase
ICLLHFKM_00480 2.6e-09 L Transposase
ICLLHFKM_00481 3.2e-51 E Filamentation induced by cAMP protein fic
ICLLHFKM_00484 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICLLHFKM_00485 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ICLLHFKM_00486 8.8e-161 xth 3.1.11.2 L exodeoxyribonuclease III
ICLLHFKM_00487 4.4e-55 S Mazg nucleotide pyrophosphohydrolase
ICLLHFKM_00488 7.7e-35
ICLLHFKM_00489 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_00490 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ICLLHFKM_00491 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICLLHFKM_00492 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICLLHFKM_00493 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICLLHFKM_00494 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICLLHFKM_00495 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICLLHFKM_00496 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICLLHFKM_00497 8.1e-123 atpB C it plays a direct role in the translocation of protons across the membrane
ICLLHFKM_00498 2.9e-232 pyrP F Permease
ICLLHFKM_00499 1.4e-124 yciB M ErfK YbiS YcfS YnhG
ICLLHFKM_00501 8.3e-48
ICLLHFKM_00502 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICLLHFKM_00503 3.6e-125 S Alpha beta hydrolase
ICLLHFKM_00504 2.2e-207 gldA 1.1.1.6 C dehydrogenase
ICLLHFKM_00505 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICLLHFKM_00506 1.3e-41
ICLLHFKM_00507 1e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
ICLLHFKM_00508 9e-284 S C4-dicarboxylate anaerobic carrier
ICLLHFKM_00509 2e-250 nhaC C Na H antiporter NhaC
ICLLHFKM_00514 4.9e-43
ICLLHFKM_00516 4.2e-92 soj D CobQ CobB MinD ParA nucleotide binding domain protein
ICLLHFKM_00517 2.4e-17 S Replication initiator protein A (RepA) N-terminus
ICLLHFKM_00522 1.6e-18
ICLLHFKM_00523 5.9e-10 gp17a S Terminase-like family
ICLLHFKM_00524 1.2e-144 gp17a S Terminase-like family
ICLLHFKM_00525 1.2e-33
ICLLHFKM_00526 1.7e-54
ICLLHFKM_00528 2.7e-68
ICLLHFKM_00534 5.5e-33
ICLLHFKM_00535 1.9e-17 O gp58-like protein
ICLLHFKM_00536 2.7e-17
ICLLHFKM_00537 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_00538 3.1e-181 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICLLHFKM_00539 2.6e-20
ICLLHFKM_00540 6.4e-09
ICLLHFKM_00542 6.5e-122 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
ICLLHFKM_00544 6.9e-107 K Belongs to the N(4) N(6)-methyltransferase family
ICLLHFKM_00547 6.4e-251 S Phage terminase, large subunit
ICLLHFKM_00548 5.1e-301 S Phage portal protein, SPP1 Gp6-like
ICLLHFKM_00549 7.7e-177 S Phage Mu protein F like protein
ICLLHFKM_00550 6.6e-95 S Domain of unknown function (DUF4355)
ICLLHFKM_00551 3e-143 gpG
ICLLHFKM_00552 5.6e-59 S Phage gp6-like head-tail connector protein
ICLLHFKM_00553 1.2e-41
ICLLHFKM_00554 2.3e-80
ICLLHFKM_00555 2.7e-70
ICLLHFKM_00556 2.6e-107
ICLLHFKM_00557 1.2e-84 S Phage tail assembly chaperone protein, TAC
ICLLHFKM_00559 5.9e-11 D NLP P60 protein
ICLLHFKM_00560 6e-137 D NLP P60 protein
ICLLHFKM_00561 1.7e-272 D NLP P60 protein
ICLLHFKM_00562 2.5e-95 S Phage tail protein
ICLLHFKM_00563 1.4e-192 S Peptidase family M23
ICLLHFKM_00566 2.5e-35 S Calcineurin-like phosphoesterase
ICLLHFKM_00567 2.6e-14 N Bacterial Ig-like domain 2
ICLLHFKM_00569 2.3e-25 S GDSL-like Lipase/Acylhydrolase
ICLLHFKM_00573 3.2e-33
ICLLHFKM_00574 1.9e-72 S Bacteriophage holin of superfamily 6 (Holin_LLH)
ICLLHFKM_00575 5.7e-185 M Glycosyl hydrolases family 25
ICLLHFKM_00577 8.7e-74
ICLLHFKM_00578 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICLLHFKM_00579 1.2e-94 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
ICLLHFKM_00580 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
ICLLHFKM_00581 6.7e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ICLLHFKM_00582 9.8e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
ICLLHFKM_00583 4.2e-217 folP 2.5.1.15 H dihydropteroate synthase
ICLLHFKM_00584 1e-43
ICLLHFKM_00585 3.3e-40
ICLLHFKM_00587 3.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICLLHFKM_00588 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICLLHFKM_00589 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ICLLHFKM_00590 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ICLLHFKM_00591 7.2e-38 yheA S Belongs to the UPF0342 family
ICLLHFKM_00592 1.3e-229 yhaO L Ser Thr phosphatase family protein
ICLLHFKM_00593 0.0 L AAA domain
ICLLHFKM_00594 7.7e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ICLLHFKM_00596 4.1e-77 hit FG histidine triad
ICLLHFKM_00597 1.2e-137 ecsA V ABC transporter, ATP-binding protein
ICLLHFKM_00598 8.4e-221 ecsB U ABC transporter
ICLLHFKM_00599 2.8e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ICLLHFKM_00600 1.1e-181 S YSIRK type signal peptide
ICLLHFKM_00601 1.4e-277 A chlorophyll binding
ICLLHFKM_00602 1e-47 gcvH E glycine cleavage
ICLLHFKM_00603 2.4e-220 rodA D Belongs to the SEDS family
ICLLHFKM_00604 2.7e-32 S Protein of unknown function (DUF2969)
ICLLHFKM_00605 1.9e-178 mbl D Cell shape determining protein MreB Mrl
ICLLHFKM_00606 6.5e-243 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICLLHFKM_00607 1.3e-33 ywzB S Protein of unknown function (DUF1146)
ICLLHFKM_00608 2.3e-162 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICLLHFKM_00609 2.3e-254 nhaC C Na H antiporter NhaC
ICLLHFKM_00610 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
ICLLHFKM_00611 5.7e-115 ywnB S NAD(P)H-binding
ICLLHFKM_00612 4.4e-38
ICLLHFKM_00613 2.6e-132 IQ Dehydrogenase reductase
ICLLHFKM_00614 4.3e-242 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
ICLLHFKM_00615 5e-148 yxeH S hydrolase
ICLLHFKM_00616 1e-270 ywfO S HD domain protein
ICLLHFKM_00617 5.1e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
ICLLHFKM_00618 1.2e-67 ywiB S Domain of unknown function (DUF1934)
ICLLHFKM_00619 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ICLLHFKM_00620 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ICLLHFKM_00621 8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICLLHFKM_00622 4.6e-41 rpmE2 J Ribosomal protein L31
ICLLHFKM_00623 6.1e-241 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICLLHFKM_00624 2.7e-168 S Alpha/beta hydrolase of unknown function (DUF915)
ICLLHFKM_00625 5.1e-125 srtA 3.4.22.70 M sortase family
ICLLHFKM_00626 1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICLLHFKM_00627 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
ICLLHFKM_00628 2.8e-117 pgm3 G Belongs to the phosphoglycerate mutase family
ICLLHFKM_00629 5.2e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICLLHFKM_00630 7e-93 lemA S LemA family
ICLLHFKM_00631 1.5e-158 htpX O Belongs to the peptidase M48B family
ICLLHFKM_00632 1.4e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ICLLHFKM_00633 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ICLLHFKM_00634 1.6e-22 sprD D Domain of Unknown Function (DUF1542)
ICLLHFKM_00635 3.6e-114 D Domain of Unknown Function (DUF1542)
ICLLHFKM_00636 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_00637 9.8e-280 arlS 2.7.13.3 T Histidine kinase
ICLLHFKM_00638 1.5e-121 K response regulator
ICLLHFKM_00639 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ICLLHFKM_00640 2.9e-99 yceD S Uncharacterized ACR, COG1399
ICLLHFKM_00641 2.9e-215 ylbM S Belongs to the UPF0348 family
ICLLHFKM_00642 1.4e-141 yqeM Q Methyltransferase
ICLLHFKM_00643 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ICLLHFKM_00644 9.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
ICLLHFKM_00645 7.9e-125 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICLLHFKM_00646 4.2e-47 yhbY J RNA-binding protein
ICLLHFKM_00647 5.6e-219 yqeH S Ribosome biogenesis GTPase YqeH
ICLLHFKM_00648 2.8e-96 yqeG S HAD phosphatase, family IIIA
ICLLHFKM_00649 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICLLHFKM_00650 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ICLLHFKM_00651 6.3e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICLLHFKM_00652 1e-173 dnaI L Primosomal protein DnaI
ICLLHFKM_00653 2.7e-207 dnaB L replication initiation and membrane attachment
ICLLHFKM_00654 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICLLHFKM_00655 9.3e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICLLHFKM_00656 2e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ICLLHFKM_00657 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICLLHFKM_00658 1.8e-119 yoaK S Protein of unknown function (DUF1275)
ICLLHFKM_00659 1.4e-119 ybhL S Belongs to the BI1 family
ICLLHFKM_00660 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ICLLHFKM_00661 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICLLHFKM_00662 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ICLLHFKM_00663 7.5e-58 ytzB S Small secreted protein
ICLLHFKM_00664 2.8e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
ICLLHFKM_00665 1.1e-186 iolS C Aldo keto reductase
ICLLHFKM_00666 3.5e-293 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
ICLLHFKM_00667 1e-218 nupG F Nucleoside transporter
ICLLHFKM_00668 2.7e-171 rihC 3.2.2.1 F Nucleoside
ICLLHFKM_00669 1.5e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
ICLLHFKM_00670 5.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
ICLLHFKM_00671 7.4e-151 noc K Belongs to the ParB family
ICLLHFKM_00672 4.7e-140 soj D Sporulation initiation inhibitor
ICLLHFKM_00673 6.5e-154 spo0J K Belongs to the ParB family
ICLLHFKM_00674 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
ICLLHFKM_00675 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ICLLHFKM_00676 9.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
ICLLHFKM_00677 3.1e-116 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICLLHFKM_00678 3.8e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICLLHFKM_00679 3.6e-24 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
ICLLHFKM_00680 2.4e-201 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
ICLLHFKM_00681 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ICLLHFKM_00682 6.9e-170 deoR K sugar-binding domain protein
ICLLHFKM_00683 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICLLHFKM_00684 3.8e-125 K response regulator
ICLLHFKM_00685 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
ICLLHFKM_00686 7.9e-139 azlC E AzlC protein
ICLLHFKM_00687 1.6e-52 azlD S branched-chain amino acid
ICLLHFKM_00688 1.2e-64 K DNA-binding transcription factor activity
ICLLHFKM_00689 3.4e-38 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ICLLHFKM_00690 4.5e-120 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ICLLHFKM_00691 7.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ICLLHFKM_00692 5.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ICLLHFKM_00693 5.1e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ICLLHFKM_00694 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICLLHFKM_00695 4.8e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
ICLLHFKM_00696 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ICLLHFKM_00697 3.1e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
ICLLHFKM_00698 6.6e-174 K AI-2E family transporter
ICLLHFKM_00699 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
ICLLHFKM_00700 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ICLLHFKM_00701 2.6e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
ICLLHFKM_00702 2.7e-24 K helix_turn_helix, arabinose operon control protein
ICLLHFKM_00703 2.9e-186 thrC 4.2.3.1 E Threonine synthase
ICLLHFKM_00704 4.9e-171 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
ICLLHFKM_00705 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ICLLHFKM_00706 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICLLHFKM_00707 7.8e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICLLHFKM_00708 1.1e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICLLHFKM_00709 6.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ICLLHFKM_00710 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICLLHFKM_00711 4.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICLLHFKM_00712 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICLLHFKM_00713 2.8e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICLLHFKM_00714 6.6e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ICLLHFKM_00715 6.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICLLHFKM_00716 2.2e-298 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ICLLHFKM_00717 1.2e-246 purD 6.3.4.13 F Belongs to the GARS family
ICLLHFKM_00718 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICLLHFKM_00719 4.1e-56 L Transposase
ICLLHFKM_00721 0.0 clpL O associated with various cellular activities
ICLLHFKM_00722 2.7e-32
ICLLHFKM_00723 5.7e-222 patA 2.6.1.1 E Aminotransferase
ICLLHFKM_00724 3.2e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICLLHFKM_00725 5e-75 osmC O OsmC-like protein
ICLLHFKM_00726 1.3e-28 2.7.13.3 T GHKL domain
ICLLHFKM_00729 1.3e-268 S Putative peptidoglycan binding domain
ICLLHFKM_00730 2.5e-20
ICLLHFKM_00732 2.8e-219 bacI V MacB-like periplasmic core domain
ICLLHFKM_00733 4.8e-128 V ABC transporter
ICLLHFKM_00734 1.4e-145 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICLLHFKM_00735 2.1e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
ICLLHFKM_00736 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICLLHFKM_00737 7.7e-85 E Glyoxalase-like domain
ICLLHFKM_00738 3.4e-56 E Glyoxalase-like domain
ICLLHFKM_00739 7.5e-155 glcU U sugar transport
ICLLHFKM_00740 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
ICLLHFKM_00741 2.2e-96 S reductase
ICLLHFKM_00743 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICLLHFKM_00744 1.8e-176 ABC-SBP S ABC transporter
ICLLHFKM_00745 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
ICLLHFKM_00746 6.4e-219 htrA 3.4.21.107 O serine protease
ICLLHFKM_00747 1.2e-154 vicX 3.1.26.11 S domain protein
ICLLHFKM_00748 2.6e-152 yycI S YycH protein
ICLLHFKM_00749 4.9e-251 yycH S YycH protein
ICLLHFKM_00750 0.0 vicK 2.7.13.3 T Histidine kinase
ICLLHFKM_00751 3.1e-130 K response regulator
ICLLHFKM_00753 0.0 lmrA 3.6.3.44 V ABC transporter
ICLLHFKM_00754 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
ICLLHFKM_00756 3.1e-101 K DNA-binding helix-turn-helix protein
ICLLHFKM_00757 2.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
ICLLHFKM_00758 1.5e-60
ICLLHFKM_00759 6.9e-207 yttB EGP Major facilitator Superfamily
ICLLHFKM_00760 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ICLLHFKM_00761 2e-74 rplI J Binds to the 23S rRNA
ICLLHFKM_00762 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ICLLHFKM_00763 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICLLHFKM_00764 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICLLHFKM_00765 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
ICLLHFKM_00766 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICLLHFKM_00767 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICLLHFKM_00768 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICLLHFKM_00769 1.7e-34 yaaA S S4 domain protein YaaA
ICLLHFKM_00770 2.9e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ICLLHFKM_00771 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICLLHFKM_00772 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
ICLLHFKM_00773 1.2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ICLLHFKM_00774 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICLLHFKM_00775 7.7e-135 jag S R3H domain protein
ICLLHFKM_00776 1.6e-76 tlpA2 L Transposase IS200 like
ICLLHFKM_00777 2.5e-228 L transposase, IS605 OrfB family
ICLLHFKM_00778 6.1e-103 manA 5.3.1.8 G mannose-6-phosphate isomerase
ICLLHFKM_00779 1.2e-22 manA 5.3.1.8 G mannose-6-phosphate isomerase
ICLLHFKM_00780 4.4e-97 2.3.1.128 K acetyltransferase
ICLLHFKM_00781 2e-183
ICLLHFKM_00782 2.6e-17 K Transcriptional regulator, HxlR family
ICLLHFKM_00783 8.1e-224 P ammonium transporter
ICLLHFKM_00784 3e-98 ureI S AmiS/UreI family transporter
ICLLHFKM_00785 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
ICLLHFKM_00786 2.9e-63 ureB 3.5.1.5 E Urease beta subunit
ICLLHFKM_00787 0.0 ureC 3.5.1.5 E Amidohydrolase family
ICLLHFKM_00788 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ICLLHFKM_00789 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
ICLLHFKM_00790 3.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ICLLHFKM_00791 5.3e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
ICLLHFKM_00792 4.9e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICLLHFKM_00793 7.6e-73 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICLLHFKM_00794 8.2e-185 nikMN P PDGLE domain
ICLLHFKM_00795 2.3e-132 P Cobalt transport protein
ICLLHFKM_00796 4.2e-135 cbiO P ABC transporter
ICLLHFKM_00797 2.1e-131 K Transcriptional regulatory protein, C-terminal domain protein
ICLLHFKM_00798 6.9e-156 pstS P Phosphate
ICLLHFKM_00799 4.7e-152 pstC P probably responsible for the translocation of the substrate across the membrane
ICLLHFKM_00800 6.5e-154 pstA P Phosphate transport system permease protein PstA
ICLLHFKM_00801 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICLLHFKM_00802 3.9e-125 phoU P Plays a role in the regulation of phosphate uptake
ICLLHFKM_00803 1.7e-135
ICLLHFKM_00804 1.2e-241 ydaM M Glycosyl transferase
ICLLHFKM_00805 1.5e-219 G Glycosyl hydrolases family 8
ICLLHFKM_00806 7.3e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
ICLLHFKM_00807 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
ICLLHFKM_00808 8.1e-241 ktrB P Potassium uptake protein
ICLLHFKM_00809 7.7e-115 ktrA P domain protein
ICLLHFKM_00810 1.9e-79 Q Methyltransferase
ICLLHFKM_00811 3.3e-231 mntH P H( )-stimulated, divalent metal cation uptake system
ICLLHFKM_00812 5.2e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
ICLLHFKM_00813 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICLLHFKM_00814 1.2e-94 S NADPH-dependent FMN reductase
ICLLHFKM_00815 8e-180 MA20_14895 S Conserved hypothetical protein 698
ICLLHFKM_00816 4.5e-137 I alpha/beta hydrolase fold
ICLLHFKM_00817 5.2e-162 lsa S ABC transporter
ICLLHFKM_00818 1.8e-101 lsa S ABC transporter
ICLLHFKM_00819 3e-181 yfeX P Peroxidase
ICLLHFKM_00820 1.5e-275 arcD S C4-dicarboxylate anaerobic carrier
ICLLHFKM_00821 6.4e-262 ytjP 3.5.1.18 E Dipeptidase
ICLLHFKM_00822 7e-215 uhpT EGP Major facilitator Superfamily
ICLLHFKM_00823 1e-281 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
ICLLHFKM_00824 2.5e-228 L transposase, IS605 OrfB family
ICLLHFKM_00825 1.6e-76 tlpA2 L Transposase IS200 like
ICLLHFKM_00826 6.7e-20 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
ICLLHFKM_00829 7.7e-41 doc S Fic/DOC family
ICLLHFKM_00830 8.5e-11
ICLLHFKM_00831 8.5e-25 S YoeB-like toxin of bacterial type II toxin-antitoxin system
ICLLHFKM_00832 5e-22 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
ICLLHFKM_00843 2e-12 ard S Antirestriction protein (ArdA)
ICLLHFKM_00845 2.5e-228 L transposase, IS605 OrfB family
ICLLHFKM_00846 1.6e-76 tlpA2 L Transposase IS200 like
ICLLHFKM_00847 5e-169
ICLLHFKM_00848 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICLLHFKM_00849 3.2e-182 S Phosphotransferase system, EIIC
ICLLHFKM_00850 0.0 UW LPXTG-motif cell wall anchor domain protein
ICLLHFKM_00852 8e-157 metQ_4 P Belongs to the nlpA lipoprotein family
ICLLHFKM_00853 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ICLLHFKM_00854 3.8e-125 O Zinc-dependent metalloprotease
ICLLHFKM_00855 2.7e-114 S Membrane
ICLLHFKM_00856 2e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
ICLLHFKM_00857 5.5e-77 S Domain of unknown function (DUF4767)
ICLLHFKM_00858 4.3e-13
ICLLHFKM_00859 2.8e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
ICLLHFKM_00860 3.1e-95 wecD3 K PFAM GCN5-related N-acetyltransferase
ICLLHFKM_00861 9.8e-169 P CorA-like Mg2+ transporter protein
ICLLHFKM_00862 2.1e-79
ICLLHFKM_00863 5.7e-120 M Lysin motif
ICLLHFKM_00864 2.2e-194 EGP Major facilitator Superfamily
ICLLHFKM_00865 2.1e-219 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICLLHFKM_00866 5e-193 nhaC C Na H antiporter NhaC
ICLLHFKM_00867 6.3e-228 E Amino acid permease
ICLLHFKM_00868 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
ICLLHFKM_00869 1.1e-98 ywlG S Belongs to the UPF0340 family
ICLLHFKM_00870 1.9e-127 L Helix-turn-helix domain
ICLLHFKM_00871 3.2e-121 L hmm pf00665
ICLLHFKM_00872 2.1e-120 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
ICLLHFKM_00873 4e-162 mleP3 S Membrane transport protein
ICLLHFKM_00874 3.4e-227 4.4.1.8 E Aminotransferase, class I
ICLLHFKM_00875 5.5e-102 M Protein of unknown function (DUF3737)
ICLLHFKM_00876 2.5e-55 yphJ 4.1.1.44 S decarboxylase
ICLLHFKM_00877 7.5e-12 S Oxidoreductase, aldo keto reductase family protein
ICLLHFKM_00878 2.9e-87 C Flavodoxin
ICLLHFKM_00880 1.3e-121 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
ICLLHFKM_00881 1.3e-128 L Belongs to the 'phage' integrase family
ICLLHFKM_00882 4e-19
ICLLHFKM_00885 1.7e-153
ICLLHFKM_00887 7.7e-129 pnuC H nicotinamide mononucleotide transporter
ICLLHFKM_00888 2.5e-103 pncA Q Isochorismatase family
ICLLHFKM_00889 3.3e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICLLHFKM_00890 1.7e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
ICLLHFKM_00891 2.4e-77 L Resolvase, N terminal domain
ICLLHFKM_00892 2.3e-07 L Resolvase, N terminal domain
ICLLHFKM_00893 1.8e-12 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
ICLLHFKM_00896 3.8e-49 ebh D nuclear chromosome segregation
ICLLHFKM_00898 5.5e-16 K Cro/C1-type HTH DNA-binding domain
ICLLHFKM_00899 2.6e-71 K Putative DNA-binding domain
ICLLHFKM_00903 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ICLLHFKM_00904 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ICLLHFKM_00905 4.4e-163 rrmA 2.1.1.187 H Methyltransferase
ICLLHFKM_00906 2.7e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
ICLLHFKM_00908 1.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
ICLLHFKM_00909 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ICLLHFKM_00910 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ICLLHFKM_00911 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ICLLHFKM_00912 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ICLLHFKM_00913 6.7e-164 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
ICLLHFKM_00914 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
ICLLHFKM_00915 3.1e-141 S Belongs to the UPF0246 family
ICLLHFKM_00916 2.5e-138 S Membrane
ICLLHFKM_00917 3.1e-74 4.4.1.5 E Glyoxalase
ICLLHFKM_00918 1.5e-21
ICLLHFKM_00919 1.7e-87 yueI S Protein of unknown function (DUF1694)
ICLLHFKM_00920 3.4e-244 rarA L recombination factor protein RarA
ICLLHFKM_00921 4.4e-46
ICLLHFKM_00922 4.3e-83 usp6 T universal stress protein
ICLLHFKM_00923 1.5e-208 araR K Transcriptional regulator
ICLLHFKM_00924 2.2e-159 ytbE 1.1.1.346 S Aldo keto reductase
ICLLHFKM_00925 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ICLLHFKM_00926 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICLLHFKM_00927 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
ICLLHFKM_00928 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ICLLHFKM_00929 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICLLHFKM_00930 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICLLHFKM_00931 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICLLHFKM_00932 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICLLHFKM_00933 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICLLHFKM_00934 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
ICLLHFKM_00935 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICLLHFKM_00936 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICLLHFKM_00937 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICLLHFKM_00938 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICLLHFKM_00939 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICLLHFKM_00940 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICLLHFKM_00941 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICLLHFKM_00942 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICLLHFKM_00943 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICLLHFKM_00944 2.9e-24 rpmD J Ribosomal protein L30
ICLLHFKM_00945 8.9e-64 rplO J Binds to the 23S rRNA
ICLLHFKM_00946 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ICLLHFKM_00947 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ICLLHFKM_00948 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICLLHFKM_00949 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ICLLHFKM_00950 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICLLHFKM_00951 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICLLHFKM_00952 3.7e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICLLHFKM_00953 1.1e-62 rplQ J Ribosomal protein L17
ICLLHFKM_00954 2.6e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICLLHFKM_00955 2.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICLLHFKM_00956 7.5e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICLLHFKM_00957 3.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ICLLHFKM_00958 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICLLHFKM_00959 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
ICLLHFKM_00960 9.4e-141 IQ reductase
ICLLHFKM_00961 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
ICLLHFKM_00962 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ICLLHFKM_00963 5.5e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICLLHFKM_00964 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ICLLHFKM_00965 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICLLHFKM_00966 1.2e-202 camS S sex pheromone
ICLLHFKM_00967 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICLLHFKM_00968 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ICLLHFKM_00969 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICLLHFKM_00970 3.5e-188 yegS 2.7.1.107 G Lipid kinase
ICLLHFKM_00971 4.1e-56 L Transposase
ICLLHFKM_00972 1.5e-29
ICLLHFKM_00973 2.5e-100 tag 3.2.2.20 L glycosylase
ICLLHFKM_00974 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICLLHFKM_00975 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICLLHFKM_00976 4.5e-42
ICLLHFKM_00977 6.4e-304 ytgP S Polysaccharide biosynthesis protein
ICLLHFKM_00978 1.2e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICLLHFKM_00979 8.7e-278 pepV 3.5.1.18 E dipeptidase PepV
ICLLHFKM_00980 1.9e-86 uspA T Belongs to the universal stress protein A family
ICLLHFKM_00981 3.2e-189 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICLLHFKM_00982 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
ICLLHFKM_00983 5.9e-114
ICLLHFKM_00984 4.6e-188 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
ICLLHFKM_00985 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICLLHFKM_00986 2.1e-32
ICLLHFKM_00987 2.8e-120 S CAAX protease self-immunity
ICLLHFKM_00989 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICLLHFKM_00990 7.1e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ICLLHFKM_00991 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICLLHFKM_00992 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ICLLHFKM_00993 1.9e-245 yifK E Amino acid permease
ICLLHFKM_00994 6.2e-293 clcA P chloride
ICLLHFKM_00995 1.8e-34 secG U Preprotein translocase
ICLLHFKM_00996 2.1e-148 est 3.1.1.1 S Serine aminopeptidase, S33
ICLLHFKM_00997 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ICLLHFKM_00998 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ICLLHFKM_00999 2.7e-258 EGP Major facilitator Superfamily
ICLLHFKM_01000 4.3e-85 perR P Belongs to the Fur family
ICLLHFKM_01001 2.2e-233 cycA E Amino acid permease
ICLLHFKM_01002 2.6e-103 V VanZ like family
ICLLHFKM_01003 1.1e-22
ICLLHFKM_01004 2.2e-85 S Short repeat of unknown function (DUF308)
ICLLHFKM_01005 1.5e-79 S Psort location Cytoplasmic, score
ICLLHFKM_01006 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
ICLLHFKM_01007 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
ICLLHFKM_01008 1e-156 yeaE S Aldo keto
ICLLHFKM_01009 4e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
ICLLHFKM_01010 7.3e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
ICLLHFKM_01011 1.2e-148 xth 3.1.11.2 L exodeoxyribonuclease III
ICLLHFKM_01012 2.3e-93 lytE M LysM domain protein
ICLLHFKM_01013 0.0 oppD EP Psort location Cytoplasmic, score
ICLLHFKM_01014 2.2e-79 lytE M LysM domain protein
ICLLHFKM_01015 1.1e-166 sufD O Uncharacterized protein family (UPF0051)
ICLLHFKM_01016 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICLLHFKM_01017 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
ICLLHFKM_01018 4.2e-240 lmrB EGP Major facilitator Superfamily
ICLLHFKM_01019 1.2e-100 2.3.1.128 K Acetyltransferase (GNAT) domain
ICLLHFKM_01020 9.5e-294 L Transposase IS66 family
ICLLHFKM_01021 1.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
ICLLHFKM_01022 2.6e-104 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
ICLLHFKM_01023 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ICLLHFKM_01025 2.6e-102 metI P ABC transporter permease
ICLLHFKM_01026 4.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICLLHFKM_01027 9.4e-150 metQ1 P Belongs to the nlpA lipoprotein family
ICLLHFKM_01028 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01029 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01030 3.3e-78 S Protein of unknown function (DUF3278)
ICLLHFKM_01031 7.8e-14 relB L RelB antitoxin
ICLLHFKM_01033 2.2e-73 M PFAM NLP P60 protein
ICLLHFKM_01034 6.4e-182 ABC-SBP S ABC transporter
ICLLHFKM_01035 3.3e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
ICLLHFKM_01036 8.2e-137 XK27_08845 S ABC transporter, ATP-binding protein
ICLLHFKM_01037 5.1e-96 P Cadmium resistance transporter
ICLLHFKM_01038 5.2e-56 K Transcriptional regulator, ArsR family
ICLLHFKM_01039 1e-240 mepA V MATE efflux family protein
ICLLHFKM_01040 1.5e-55 trxA O Belongs to the thioredoxin family
ICLLHFKM_01041 2.3e-131 terC P membrane
ICLLHFKM_01042 2.4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICLLHFKM_01043 1.5e-166 corA P CorA-like Mg2+ transporter protein
ICLLHFKM_01044 2.4e-283 pipD E Dipeptidase
ICLLHFKM_01045 8.1e-241 pbuX F xanthine permease
ICLLHFKM_01046 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01047 8.4e-99 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
ICLLHFKM_01048 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01049 1.9e-89 ygfC K transcriptional regulator (TetR family)
ICLLHFKM_01050 4e-174 hrtB V ABC transporter permease
ICLLHFKM_01051 3.7e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
ICLLHFKM_01052 0.0 yhcA V ABC transporter, ATP-binding protein
ICLLHFKM_01053 3e-37
ICLLHFKM_01054 4.1e-50 czrA K Transcriptional regulator, ArsR family
ICLLHFKM_01055 3.8e-227 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICLLHFKM_01056 1.2e-174 scrR K Transcriptional regulator, LacI family
ICLLHFKM_01057 1e-24
ICLLHFKM_01058 8.2e-103
ICLLHFKM_01059 1.6e-216 yttB EGP Major facilitator Superfamily
ICLLHFKM_01060 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
ICLLHFKM_01061 9.1e-89
ICLLHFKM_01062 2.7e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
ICLLHFKM_01063 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01064 1.2e-53 L Belongs to the 'phage' integrase family
ICLLHFKM_01065 1.6e-10 E Zn peptidase
ICLLHFKM_01066 5.8e-12 S protein disulfide oxidoreductase activity
ICLLHFKM_01069 6.5e-14
ICLLHFKM_01071 4.7e-21 L Psort location Cytoplasmic, score
ICLLHFKM_01085 2.9e-12
ICLLHFKM_01093 9.3e-32 V Abi-like protein
ICLLHFKM_01094 2.1e-48 V Abi-like protein
ICLLHFKM_01095 7.5e-65 ruvB 3.6.4.12 L four-way junction helicase activity
ICLLHFKM_01098 3.9e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
ICLLHFKM_01099 2.1e-10 T PFAM SpoVT AbrB
ICLLHFKM_01101 6.1e-10 3.2.1.80, 3.4.24.40 L Protein of unknown function (DUF3991)
ICLLHFKM_01102 1.5e-72
ICLLHFKM_01105 7.6e-18 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICLLHFKM_01106 2.8e-13 V Type I restriction-modification system methyltransferase subunit()
ICLLHFKM_01107 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01108 5.5e-110 dedA S SNARE-like domain protein
ICLLHFKM_01109 2.8e-114 S Protein of unknown function (DUF1461)
ICLLHFKM_01110 2.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ICLLHFKM_01111 4.4e-100 yutD S Protein of unknown function (DUF1027)
ICLLHFKM_01112 8.8e-118 S Calcineurin-like phosphoesterase
ICLLHFKM_01113 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICLLHFKM_01114 7.7e-146 ytxK 2.1.1.72 L N-6 DNA Methylase
ICLLHFKM_01116 1.4e-72
ICLLHFKM_01117 1.8e-44
ICLLHFKM_01118 1.5e-79 NU general secretion pathway protein
ICLLHFKM_01119 7.1e-47 comGC U competence protein ComGC
ICLLHFKM_01120 1.3e-185 comGB NU type II secretion system
ICLLHFKM_01121 7.9e-185 comGA NU Type II IV secretion system protein
ICLLHFKM_01123 8.6e-141 topA2 5.99.1.2 G Topoisomerase IA
ICLLHFKM_01124 1.8e-17 S sequence-specific DNA binding
ICLLHFKM_01125 3.9e-50 L Protein of unknown function (DUF3991)
ICLLHFKM_01126 1e-08 nrdH O Glutaredoxin
ICLLHFKM_01129 2.3e-15 K ORF6N domain
ICLLHFKM_01130 9.4e-33 XK27_00515 D Glucan-binding protein C
ICLLHFKM_01131 1.3e-12 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICLLHFKM_01132 7.1e-11 ftsZ D Cell surface antigen C-terminus
ICLLHFKM_01133 3.3e-92 L Belongs to the 'phage' integrase family
ICLLHFKM_01134 2.3e-36 3.1.21.3 V Type I restriction modification DNA specificity domain
ICLLHFKM_01135 4.3e-133 V Type I restriction-modification system methyltransferase subunit()
ICLLHFKM_01136 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01138 2.4e-259 3.4.24.40 M Peptidase family M23
ICLLHFKM_01140 0.0 M Prophage endopeptidase tail
ICLLHFKM_01141 1.8e-147 S phage tail
ICLLHFKM_01142 1.9e-257 sca1 D Phage tail tape measure protein
ICLLHFKM_01143 2.7e-61
ICLLHFKM_01144 1.6e-52 S Phage tail assembly chaperone protein, TAC
ICLLHFKM_01145 9.1e-104 S Phage tail tube protein
ICLLHFKM_01146 4.9e-21 S Protein of unknown function (DUF3168)
ICLLHFKM_01147 2.3e-69 S Bacteriophage HK97-gp10, putative tail-component
ICLLHFKM_01148 1.5e-52
ICLLHFKM_01149 2.4e-63 S Phage gp6-like head-tail connector protein
ICLLHFKM_01150 1.4e-156
ICLLHFKM_01151 1.1e-103 S Domain of unknown function (DUF4355)
ICLLHFKM_01153 1.8e-174 S Phage Mu protein F like protein
ICLLHFKM_01154 3.9e-273 S Phage portal protein
ICLLHFKM_01155 2.7e-246 S Phage terminase, large subunit
ICLLHFKM_01157 5.5e-61 L Terminase small subunit
ICLLHFKM_01159 4.2e-80 arpU S Phage transcriptional regulator, ArpU family
ICLLHFKM_01160 9.2e-21
ICLLHFKM_01164 2.6e-18 Q DNA (cytosine-5-)-methyltransferase activity
ICLLHFKM_01166 3.7e-22
ICLLHFKM_01168 1e-57 S VRR_NUC
ICLLHFKM_01171 1.1e-231 S Virulence-associated protein E
ICLLHFKM_01172 1.3e-145 S Bifunctional DNA primase/polymerase, N-terminal
ICLLHFKM_01173 1.4e-92
ICLLHFKM_01174 1.2e-140 L AAA domain
ICLLHFKM_01175 1.9e-242 res L Helicase C-terminal domain protein
ICLLHFKM_01176 5.7e-80 S Siphovirus Gp157
ICLLHFKM_01179 9e-28
ICLLHFKM_01182 5.7e-39
ICLLHFKM_01184 6e-15 XK27_10050 K Peptidase S24-like
ICLLHFKM_01185 8.3e-20 E Zn peptidase
ICLLHFKM_01187 2.2e-11
ICLLHFKM_01188 1.1e-211 L Belongs to the 'phage' integrase family
ICLLHFKM_01189 2.8e-93
ICLLHFKM_01190 3.4e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ICLLHFKM_01191 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLLHFKM_01192 5.1e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
ICLLHFKM_01193 2.6e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICLLHFKM_01195 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ICLLHFKM_01196 7.9e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICLLHFKM_01197 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
ICLLHFKM_01198 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
ICLLHFKM_01199 2.1e-243 codA 3.5.4.1 F cytosine deaminase
ICLLHFKM_01200 1.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
ICLLHFKM_01201 8.9e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
ICLLHFKM_01202 6e-108 tdk 2.7.1.21 F thymidine kinase
ICLLHFKM_01203 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICLLHFKM_01204 3.1e-169 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ICLLHFKM_01205 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ICLLHFKM_01206 9.8e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICLLHFKM_01207 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICLLHFKM_01208 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICLLHFKM_01209 3.3e-195 yibE S overlaps another CDS with the same product name
ICLLHFKM_01210 1.8e-131 yibF S overlaps another CDS with the same product name
ICLLHFKM_01211 7.7e-48
ICLLHFKM_01213 3.6e-37 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ICLLHFKM_01214 3.1e-131 ponA V Beta-lactamase enzyme family
ICLLHFKM_01215 3e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICLLHFKM_01216 3e-75
ICLLHFKM_01217 8.2e-109 proWZ P ABC transporter permease
ICLLHFKM_01218 3e-139 proV E ABC transporter, ATP-binding protein
ICLLHFKM_01219 4.5e-104 proW P ABC transporter, permease protein
ICLLHFKM_01220 6.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ICLLHFKM_01221 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICLLHFKM_01222 4.4e-150 yihY S Belongs to the UPF0761 family
ICLLHFKM_01223 4.6e-228 yjeM E Amino Acid
ICLLHFKM_01224 9.8e-71 E Arginine ornithine antiporter
ICLLHFKM_01225 1.6e-160 E Arginine ornithine antiporter
ICLLHFKM_01226 5.4e-222 arcT 2.6.1.1 E Aminotransferase
ICLLHFKM_01227 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
ICLLHFKM_01228 6.1e-79 fld C Flavodoxin
ICLLHFKM_01229 1.3e-73 gtcA S Teichoic acid glycosylation protein
ICLLHFKM_01230 2.5e-56
ICLLHFKM_01231 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICLLHFKM_01233 6.7e-232 yfmL L DEAD DEAH box helicase
ICLLHFKM_01234 1.2e-191 mocA S Oxidoreductase
ICLLHFKM_01235 7.7e-61 S Domain of unknown function (DUF4828)
ICLLHFKM_01236 1.3e-110 yvdD 3.2.2.10 S Belongs to the LOG family
ICLLHFKM_01237 2.7e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICLLHFKM_01238 3.1e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ICLLHFKM_01239 1.1e-200 S Protein of unknown function (DUF3114)
ICLLHFKM_01240 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
ICLLHFKM_01241 1.9e-119 ybhL S Belongs to the BI1 family
ICLLHFKM_01242 2.2e-202 yhjX P Major Facilitator Superfamily
ICLLHFKM_01243 6.3e-22
ICLLHFKM_01244 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01245 2.5e-155 KT YcbB domain
ICLLHFKM_01246 2.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICLLHFKM_01247 1.5e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
ICLLHFKM_01248 1.2e-163 EG EamA-like transporter family
ICLLHFKM_01249 2e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ICLLHFKM_01250 7.6e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ICLLHFKM_01251 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ICLLHFKM_01252 0.0 copA 3.6.3.54 P P-type ATPase
ICLLHFKM_01253 1.6e-90
ICLLHFKM_01255 3.6e-57
ICLLHFKM_01256 6.6e-241 yjcE P Sodium proton antiporter
ICLLHFKM_01258 3.1e-147 tesE Q hydratase
ICLLHFKM_01259 3.6e-114 S (CBS) domain
ICLLHFKM_01260 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ICLLHFKM_01261 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICLLHFKM_01262 4.8e-39 yabO J S4 domain protein
ICLLHFKM_01263 2.3e-57 divIC D Septum formation initiator
ICLLHFKM_01264 9.8e-67 yabR J RNA binding
ICLLHFKM_01265 1.6e-268 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ICLLHFKM_01266 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ICLLHFKM_01267 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICLLHFKM_01268 3.6e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICLLHFKM_01269 1.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICLLHFKM_01270 4.2e-294 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ICLLHFKM_01271 1.7e-88
ICLLHFKM_01272 2.5e-161 mleR K LysR family
ICLLHFKM_01273 3.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
ICLLHFKM_01274 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ICLLHFKM_01275 3.1e-267 frdC 1.3.5.4 C FAD binding domain
ICLLHFKM_01276 5.9e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICLLHFKM_01277 5.5e-171 citP P Sodium:sulfate symporter transmembrane region
ICLLHFKM_01278 6.3e-123 citR K sugar-binding domain protein
ICLLHFKM_01279 1.2e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
ICLLHFKM_01280 2.2e-148 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ICLLHFKM_01281 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
ICLLHFKM_01282 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
ICLLHFKM_01283 9.2e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
ICLLHFKM_01284 5e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
ICLLHFKM_01285 7.2e-112 ydjP I Alpha/beta hydrolase family
ICLLHFKM_01286 3e-159 mleR K LysR family
ICLLHFKM_01287 9.4e-253 yjjP S Putative threonine/serine exporter
ICLLHFKM_01288 1e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
ICLLHFKM_01289 5.5e-281 emrY EGP Major facilitator Superfamily
ICLLHFKM_01290 7.7e-188 I Alpha beta
ICLLHFKM_01291 1.5e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
ICLLHFKM_01293 1.9e-40
ICLLHFKM_01294 0.0 lacS G Transporter
ICLLHFKM_01295 2.1e-79 ltrA S Bacterial low temperature requirement A protein (LtrA)
ICLLHFKM_01296 2e-36 ltrA S Bacterial low temperature requirement A protein (LtrA)
ICLLHFKM_01297 1.6e-79 uspA T universal stress protein
ICLLHFKM_01298 1.8e-78 K AsnC family
ICLLHFKM_01299 7.6e-09
ICLLHFKM_01300 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ICLLHFKM_01301 4.7e-249 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICLLHFKM_01302 9.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ICLLHFKM_01303 1.3e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ICLLHFKM_01304 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ICLLHFKM_01305 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICLLHFKM_01306 2.8e-87
ICLLHFKM_01307 6.3e-105 yxjI
ICLLHFKM_01308 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICLLHFKM_01309 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
ICLLHFKM_01310 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
ICLLHFKM_01311 4.2e-84 K Acetyltransferase (GNAT) domain
ICLLHFKM_01312 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_01313 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ICLLHFKM_01314 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICLLHFKM_01315 7e-217 iscS2 2.8.1.7 E Aminotransferase class V
ICLLHFKM_01316 9e-253 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ICLLHFKM_01317 1.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICLLHFKM_01318 1.1e-235 pbuG S permease
ICLLHFKM_01319 3.1e-203 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
ICLLHFKM_01320 2e-22
ICLLHFKM_01321 2e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
ICLLHFKM_01322 2e-183 L PFAM plasmid pRiA4b ORF-3 family protein
ICLLHFKM_01323 6e-90 L PFAM plasmid pRiA4b ORF-3 family protein
ICLLHFKM_01324 2.7e-207 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
ICLLHFKM_01325 3.9e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICLLHFKM_01326 8.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICLLHFKM_01327 7.4e-160 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
ICLLHFKM_01328 0.0 ysaB V FtsX-like permease family
ICLLHFKM_01329 6.8e-136 macB2 V ABC transporter, ATP-binding protein
ICLLHFKM_01330 8.7e-184 T Histidine kinase-like ATPases
ICLLHFKM_01331 3.4e-126 K response regulator
ICLLHFKM_01332 2.9e-159 ytbE 1.1.1.346 S Aldo keto reductase
ICLLHFKM_01333 1.8e-136 pnuC H nicotinamide mononucleotide transporter
ICLLHFKM_01334 1.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICLLHFKM_01335 4.6e-205
ICLLHFKM_01336 9.1e-53
ICLLHFKM_01337 9.1e-36
ICLLHFKM_01338 3.7e-93 yxkA S Phosphatidylethanolamine-binding protein
ICLLHFKM_01339 1.5e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
ICLLHFKM_01340 8.3e-187 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
ICLLHFKM_01341 1.2e-227 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICLLHFKM_01342 1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ICLLHFKM_01343 1.8e-181 galR K Transcriptional regulator
ICLLHFKM_01344 3.3e-68 rmaI K Transcriptional regulator
ICLLHFKM_01345 1.4e-248 EGP Major facilitator Superfamily
ICLLHFKM_01346 2.6e-112 yvyE 3.4.13.9 S YigZ family
ICLLHFKM_01347 3.3e-258 comFA L Helicase C-terminal domain protein
ICLLHFKM_01348 2.6e-126 comFC S Competence protein
ICLLHFKM_01349 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICLLHFKM_01350 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICLLHFKM_01351 9.2e-189 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICLLHFKM_01352 2.4e-32 KT PspC domain protein
ICLLHFKM_01353 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
ICLLHFKM_01354 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICLLHFKM_01355 1.3e-159 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICLLHFKM_01356 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ICLLHFKM_01357 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ICLLHFKM_01358 2.4e-138 yrjD S LUD domain
ICLLHFKM_01359 9.8e-296 lutB C 4Fe-4S dicluster domain
ICLLHFKM_01360 1.9e-169 lutA C Cysteine-rich domain
ICLLHFKM_01361 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ICLLHFKM_01362 7.6e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICLLHFKM_01363 1.6e-165 aatB ET PFAM extracellular solute-binding protein, family 3
ICLLHFKM_01364 9.1e-84 ykhA 3.1.2.20 I Thioesterase superfamily
ICLLHFKM_01365 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ICLLHFKM_01366 2.3e-116 yfbR S HD containing hydrolase-like enzyme
ICLLHFKM_01367 1.5e-13
ICLLHFKM_01368 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICLLHFKM_01369 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ICLLHFKM_01370 5.4e-245 steT E amino acid
ICLLHFKM_01371 1.9e-161 rapZ S Displays ATPase and GTPase activities
ICLLHFKM_01372 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ICLLHFKM_01373 3.1e-170 whiA K May be required for sporulation
ICLLHFKM_01375 8.8e-15
ICLLHFKM_01376 1.5e-203 glpT G Major Facilitator Superfamily
ICLLHFKM_01377 4.8e-25 glpT G Major Facilitator Superfamily
ICLLHFKM_01378 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ICLLHFKM_01379 1.8e-143 L Transposase
ICLLHFKM_01382 2.6e-132 pnuC H nicotinamide mononucleotide transporter
ICLLHFKM_01386 1.9e-22 S AAA ATPase domain
ICLLHFKM_01400 1.9e-50 L HNH nucleases
ICLLHFKM_01401 4.1e-75 L Phage terminase, small subunit
ICLLHFKM_01402 8e-276 S Phage Terminase
ICLLHFKM_01403 2.9e-145 S portal protein
ICLLHFKM_01404 3e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
ICLLHFKM_01405 1.5e-131 S Phage capsid family
ICLLHFKM_01406 1.7e-44 S Phage gp6-like head-tail connector protein
ICLLHFKM_01407 1.5e-37 S Phage head-tail joining protein
ICLLHFKM_01408 1.3e-20
ICLLHFKM_01409 1.7e-24
ICLLHFKM_01410 2.4e-66 S Phage tail tube protein
ICLLHFKM_01411 1.5e-17
ICLLHFKM_01412 0.0 M Phage tail tape measure protein TP901
ICLLHFKM_01413 1.2e-112 S Phage tail protein
ICLLHFKM_01414 9.3e-203 M Prophage endopeptidase tail
ICLLHFKM_01415 2.4e-13 tcdA2 GT2,GT4 LM gp58-like protein
ICLLHFKM_01418 9e-31 S GDSL-like Lipase/Acylhydrolase
ICLLHFKM_01419 1e-209
ICLLHFKM_01422 1.5e-76
ICLLHFKM_01424 1.3e-35
ICLLHFKM_01425 1.1e-59 hol S COG5546 Small integral membrane protein
ICLLHFKM_01426 3.4e-174 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ICLLHFKM_01428 2e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ICLLHFKM_01429 8.2e-193 ypbB 5.1.3.1 S Helix-turn-helix domain
ICLLHFKM_01430 2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
ICLLHFKM_01431 8.5e-14 M Lysin motif
ICLLHFKM_01432 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ICLLHFKM_01433 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
ICLLHFKM_01434 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ICLLHFKM_01435 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICLLHFKM_01436 8.8e-237 S Tetratricopeptide repeat protein
ICLLHFKM_01437 3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ICLLHFKM_01438 0.0 yfmR S ABC transporter, ATP-binding protein
ICLLHFKM_01439 7.7e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICLLHFKM_01440 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICLLHFKM_01441 5.3e-113 hlyIII S protein, hemolysin III
ICLLHFKM_01442 9.9e-152 DegV S EDD domain protein, DegV family
ICLLHFKM_01443 1.8e-170 ypmR E lipolytic protein G-D-S-L family
ICLLHFKM_01444 1.3e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
ICLLHFKM_01445 4.4e-35 yozE S Belongs to the UPF0346 family
ICLLHFKM_01446 1.9e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ICLLHFKM_01447 4.5e-143 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICLLHFKM_01448 1.7e-162 dprA LU DNA protecting protein DprA
ICLLHFKM_01449 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICLLHFKM_01450 1e-167 lacX 5.1.3.3 G Aldose 1-epimerase
ICLLHFKM_01451 7.2e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ICLLHFKM_01452 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICLLHFKM_01453 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICLLHFKM_01454 1.7e-84 F NUDIX domain
ICLLHFKM_01455 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
ICLLHFKM_01456 8.3e-69 yqkB S Belongs to the HesB IscA family
ICLLHFKM_01457 2.7e-49
ICLLHFKM_01459 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
ICLLHFKM_01460 8.7e-63 asp S Asp23 family, cell envelope-related function
ICLLHFKM_01461 2.3e-24
ICLLHFKM_01462 7.2e-95
ICLLHFKM_01463 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ICLLHFKM_01464 5.2e-184 K Transcriptional regulator, LacI family
ICLLHFKM_01465 3.7e-173 1.1.1.346 C Aldo keto reductase
ICLLHFKM_01466 2.1e-39 gcvR T Belongs to the UPF0237 family
ICLLHFKM_01467 6e-244 XK27_08635 S UPF0210 protein
ICLLHFKM_01468 9.4e-150 metQ1 P Belongs to the nlpA lipoprotein family
ICLLHFKM_01469 4.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICLLHFKM_01470 3.1e-103 metI P ABC transporter permease
ICLLHFKM_01471 1.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICLLHFKM_01472 1.7e-251 clcA P chloride
ICLLHFKM_01475 4.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICLLHFKM_01476 9.4e-150 metQ1 P Belongs to the nlpA lipoprotein family
ICLLHFKM_01477 4.5e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICLLHFKM_01478 3.9e-70 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ICLLHFKM_01479 9e-185 gadC E amino acid
ICLLHFKM_01480 1.5e-266 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
ICLLHFKM_01481 2.2e-35 pbuG S permease
ICLLHFKM_01482 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
ICLLHFKM_01483 4.4e-34 S Domain of unknown function (DUF4430)
ICLLHFKM_01484 2.4e-90 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
ICLLHFKM_01485 1.7e-143 L Transposase
ICLLHFKM_01486 4.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICLLHFKM_01487 9.4e-150 metQ1 P Belongs to the nlpA lipoprotein family
ICLLHFKM_01488 1.4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICLLHFKM_01489 1.7e-221 norA EGP Major facilitator Superfamily
ICLLHFKM_01490 8.6e-44 1.3.5.4 S FMN binding
ICLLHFKM_01491 4.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICLLHFKM_01492 2.8e-266 yfnA E amino acid
ICLLHFKM_01493 8.5e-85 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICLLHFKM_01494 7e-161 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICLLHFKM_01496 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICLLHFKM_01497 0.0 helD 3.6.4.12 L DNA helicase
ICLLHFKM_01498 1.7e-81 ndk 2.7.4.6 F Belongs to the NDK family
ICLLHFKM_01499 1.3e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
ICLLHFKM_01500 4.2e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICLLHFKM_01501 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICLLHFKM_01502 1.3e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
ICLLHFKM_01503 1.1e-178
ICLLHFKM_01504 4.2e-132 cobB K SIR2 family
ICLLHFKM_01506 7.4e-163 yunF F Protein of unknown function DUF72
ICLLHFKM_01507 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICLLHFKM_01508 6.4e-156 tatD L hydrolase, TatD family
ICLLHFKM_01509 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ICLLHFKM_01510 9.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ICLLHFKM_01511 6.8e-37 veg S Biofilm formation stimulator VEG
ICLLHFKM_01512 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICLLHFKM_01513 2.8e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
ICLLHFKM_01514 3.2e-121 fhuC P ABC transporter
ICLLHFKM_01515 2.3e-126 znuB U ABC 3 transport family
ICLLHFKM_01516 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ICLLHFKM_01517 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICLLHFKM_01518 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICLLHFKM_01519 1.4e-48
ICLLHFKM_01520 2.1e-26
ICLLHFKM_01521 2e-263 pgi 5.3.1.9 G Belongs to the GPI family
ICLLHFKM_01522 1.4e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
ICLLHFKM_01523 5.7e-155 glcU U sugar transport
ICLLHFKM_01524 8.1e-274 yclK 2.7.13.3 T Histidine kinase
ICLLHFKM_01525 3.8e-136 K response regulator
ICLLHFKM_01527 1.8e-78 lytE M Lysin motif
ICLLHFKM_01528 8.9e-150 XK27_02985 S Cof-like hydrolase
ICLLHFKM_01529 2.1e-79 K Transcriptional regulator
ICLLHFKM_01530 0.0 oatA I Acyltransferase
ICLLHFKM_01531 8.7e-53
ICLLHFKM_01532 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ICLLHFKM_01533 2.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICLLHFKM_01534 1.2e-126 ybbR S YbbR-like protein
ICLLHFKM_01535 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICLLHFKM_01536 4.4e-103 fucP G Major Facilitator Superfamily
ICLLHFKM_01537 1.3e-123 fucP G Major Facilitator Superfamily
ICLLHFKM_01538 6e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ICLLHFKM_01539 1.2e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICLLHFKM_01540 7.3e-169 murB 1.3.1.98 M Cell wall formation
ICLLHFKM_01541 3.5e-102 dnaQ 2.7.7.7 L DNA polymerase III
ICLLHFKM_01542 8.9e-77 S PAS domain
ICLLHFKM_01543 9.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICLLHFKM_01544 2.1e-197 EGP Major facilitator Superfamily
ICLLHFKM_01545 1.5e-91 ymdB S Macro domain protein
ICLLHFKM_01546 3.9e-113 K Helix-turn-helix XRE-family like proteins
ICLLHFKM_01547 0.0 pepO 3.4.24.71 O Peptidase family M13
ICLLHFKM_01548 3.6e-48
ICLLHFKM_01549 5.6e-247 S Putative metallopeptidase domain
ICLLHFKM_01550 1.4e-209 3.1.3.1 S associated with various cellular activities
ICLLHFKM_01551 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ICLLHFKM_01552 1.4e-65 yeaO S Protein of unknown function, DUF488
ICLLHFKM_01554 6e-123 yrkL S Flavodoxin-like fold
ICLLHFKM_01555 1.6e-54
ICLLHFKM_01556 3.3e-18 S Domain of unknown function (DUF4767)
ICLLHFKM_01557 9.2e-141 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ICLLHFKM_01558 1.1e-49
ICLLHFKM_01559 1.4e-206 nrnB S DHHA1 domain
ICLLHFKM_01560 5.4e-231 S Uncharacterized protein conserved in bacteria (DUF2325)
ICLLHFKM_01561 2.2e-249 brnQ U Component of the transport system for branched-chain amino acids
ICLLHFKM_01562 1.5e-106 NU mannosyl-glycoprotein
ICLLHFKM_01563 1.8e-147 S Putative ABC-transporter type IV
ICLLHFKM_01564 1.3e-274 S ABC transporter, ATP-binding protein
ICLLHFKM_01565 2.9e-11
ICLLHFKM_01567 2.4e-23 S Protein of unknown function (DUF3278)
ICLLHFKM_01568 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01569 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_01570 8.4e-27 cylA V ABC transporter
ICLLHFKM_01571 7.4e-47
ICLLHFKM_01572 0.0 XK27_08510 L Type III restriction protein res subunit
ICLLHFKM_01573 1.5e-147 S PFAM Archaeal ATPase
ICLLHFKM_01574 1.4e-86 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ICLLHFKM_01575 1.2e-206 amtB P ammonium transporter
ICLLHFKM_01576 1.3e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
ICLLHFKM_01577 1.5e-19 S B3 4 domain
ICLLHFKM_01578 2.9e-39 S B3 4 domain
ICLLHFKM_01579 1.5e-89
ICLLHFKM_01580 4.4e-123 pnb C nitroreductase
ICLLHFKM_01581 3.5e-74 ogt 2.1.1.63 L Methyltransferase
ICLLHFKM_01582 4.2e-171 XK27_00915 C Luciferase-like monooxygenase
ICLLHFKM_01583 1.4e-154 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
ICLLHFKM_01584 4.7e-68 S Protein of unknown function (DUF3021)
ICLLHFKM_01585 6.4e-78 K LytTr DNA-binding domain
ICLLHFKM_01586 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01587 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_01588 9.9e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICLLHFKM_01589 3.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
ICLLHFKM_01590 4.1e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
ICLLHFKM_01591 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ICLLHFKM_01592 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICLLHFKM_01593 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
ICLLHFKM_01594 1.2e-216 nusA K Participates in both transcription termination and antitermination
ICLLHFKM_01595 1e-44 ylxR K Protein of unknown function (DUF448)
ICLLHFKM_01596 4.5e-49 ylxQ J ribosomal protein
ICLLHFKM_01597 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICLLHFKM_01598 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICLLHFKM_01599 1.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICLLHFKM_01600 1.9e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ICLLHFKM_01601 7.6e-64
ICLLHFKM_01602 1.2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ICLLHFKM_01603 1.2e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICLLHFKM_01604 0.0 dnaK O Heat shock 70 kDa protein
ICLLHFKM_01605 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ICLLHFKM_01606 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ICLLHFKM_01607 5.4e-225 3.6.4.12 L Belongs to the 'phage' integrase family
ICLLHFKM_01608 8.1e-142
ICLLHFKM_01609 6.4e-13
ICLLHFKM_01610 4.7e-76
ICLLHFKM_01611 1e-81
ICLLHFKM_01612 1.4e-10 3.4.21.88 K Peptidase S24-like
ICLLHFKM_01613 9.2e-24 3.4.21.88 K Peptidase S24-like
ICLLHFKM_01614 2.3e-278 pipD E Dipeptidase
ICLLHFKM_01615 1.7e-201 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
ICLLHFKM_01616 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICLLHFKM_01617 7.5e-58
ICLLHFKM_01618 1.6e-182 prmA J Ribosomal protein L11 methyltransferase
ICLLHFKM_01619 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ICLLHFKM_01620 9.3e-53
ICLLHFKM_01621 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICLLHFKM_01622 3.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ICLLHFKM_01623 1.2e-165 yniA G Phosphotransferase enzyme family
ICLLHFKM_01624 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ICLLHFKM_01625 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICLLHFKM_01626 1.1e-265 glnPH2 P ABC transporter permease
ICLLHFKM_01627 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ICLLHFKM_01628 7.3e-69 yqeY S YqeY-like protein
ICLLHFKM_01629 1.5e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ICLLHFKM_01630 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ICLLHFKM_01631 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
ICLLHFKM_01632 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_01633 1.4e-13 K BRO family, N-terminal domain
ICLLHFKM_01638 2.1e-09
ICLLHFKM_01641 4.6e-08 K Psort location CytoplasmicMembrane, score
ICLLHFKM_01642 1.3e-30 3.4.21.88 K Helix-turn-helix domain
ICLLHFKM_01643 1.2e-49 S Pfam:DUF955
ICLLHFKM_01644 1.6e-62
ICLLHFKM_01645 1.2e-25
ICLLHFKM_01647 2.8e-46
ICLLHFKM_01648 2.2e-103 L Belongs to the 'phage' integrase family
ICLLHFKM_01650 1.9e-43
ICLLHFKM_01651 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_01652 4.4e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
ICLLHFKM_01653 1.4e-118 rfbP 2.7.8.6 M Bacterial sugar transferase
ICLLHFKM_01654 2.3e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
ICLLHFKM_01655 3e-147 cps1D M Domain of unknown function (DUF4422)
ICLLHFKM_01656 1.5e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
ICLLHFKM_01657 1.3e-84
ICLLHFKM_01659 1.9e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
ICLLHFKM_01660 2.7e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICLLHFKM_01661 1e-104 pncA Q Isochorismatase family
ICLLHFKM_01662 1.1e-208 yegU O ADP-ribosylglycohydrolase
ICLLHFKM_01663 1.8e-256 F Belongs to the purine-cytosine permease (2.A.39) family
ICLLHFKM_01664 3e-167 G Belongs to the carbohydrate kinase PfkB family
ICLLHFKM_01665 5.6e-39 hxlR K regulation of RNA biosynthetic process
ICLLHFKM_01666 2.2e-229 L transposase, IS605 OrfB family
ICLLHFKM_01667 1.2e-10 S Protein of unknown function (DUF4044)
ICLLHFKM_01668 3e-57
ICLLHFKM_01669 3.1e-77 mraZ K Belongs to the MraZ family
ICLLHFKM_01670 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ICLLHFKM_01671 1.5e-56 ftsL D Cell division protein FtsL
ICLLHFKM_01672 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ICLLHFKM_01673 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICLLHFKM_01674 2.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICLLHFKM_01675 9.2e-206 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICLLHFKM_01676 1.3e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ICLLHFKM_01677 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ICLLHFKM_01678 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICLLHFKM_01679 1.2e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ICLLHFKM_01680 8.3e-41 yggT S YGGT family
ICLLHFKM_01681 1.3e-145 ylmH S S4 domain protein
ICLLHFKM_01682 6.4e-38 divIVA D DivIVA domain protein
ICLLHFKM_01683 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICLLHFKM_01684 4.2e-32 cspA K Cold shock protein
ICLLHFKM_01685 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
ICLLHFKM_01687 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICLLHFKM_01688 8.3e-218 iscS 2.8.1.7 E Aminotransferase class V
ICLLHFKM_01689 7.5e-58 XK27_04120 S Putative amino acid metabolism
ICLLHFKM_01690 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ICLLHFKM_01691 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
ICLLHFKM_01692 3.4e-118 S Repeat protein
ICLLHFKM_01693 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ICLLHFKM_01694 2.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICLLHFKM_01695 2.7e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICLLHFKM_01696 2.1e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
ICLLHFKM_01697 1e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ICLLHFKM_01698 2.1e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ICLLHFKM_01699 7e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ICLLHFKM_01700 7.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICLLHFKM_01701 6.6e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ICLLHFKM_01702 1.3e-221 patA 2.6.1.1 E Aminotransferase
ICLLHFKM_01703 6.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICLLHFKM_01704 1.1e-83 KT Putative sugar diacid recognition
ICLLHFKM_01705 3.1e-210 EG GntP family permease
ICLLHFKM_01706 1.5e-211 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ICLLHFKM_01707 7.7e-58
ICLLHFKM_01709 8.7e-140 mltD CBM50 M NlpC P60 family protein
ICLLHFKM_01710 5.7e-29
ICLLHFKM_01711 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
ICLLHFKM_01712 9.8e-32 ykzG S Belongs to the UPF0356 family
ICLLHFKM_01713 3.6e-82
ICLLHFKM_01714 5.6e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICLLHFKM_01715 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
ICLLHFKM_01716 6.2e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
ICLLHFKM_01717 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICLLHFKM_01718 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
ICLLHFKM_01719 6.1e-48 yktA S Belongs to the UPF0223 family
ICLLHFKM_01720 5.7e-138 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
ICLLHFKM_01721 0.0 typA T GTP-binding protein TypA
ICLLHFKM_01722 8.2e-224 ftsW D Belongs to the SEDS family
ICLLHFKM_01723 1e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
ICLLHFKM_01724 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
ICLLHFKM_01725 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICLLHFKM_01726 4.6e-199 ylbL T Belongs to the peptidase S16 family
ICLLHFKM_01727 9e-81 comEA L Competence protein ComEA
ICLLHFKM_01728 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
ICLLHFKM_01729 0.0 comEC S Competence protein ComEC
ICLLHFKM_01730 2.5e-149 holA 2.7.7.7 L DNA polymerase III delta subunit
ICLLHFKM_01731 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
ICLLHFKM_01732 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICLLHFKM_01733 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICLLHFKM_01734 4.9e-165 S Tetratricopeptide repeat
ICLLHFKM_01735 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICLLHFKM_01736 6.3e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ICLLHFKM_01737 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICLLHFKM_01738 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
ICLLHFKM_01739 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
ICLLHFKM_01740 2.9e-36 L Transposase
ICLLHFKM_01741 0.0 fhaB M Rib/alpha-like repeat
ICLLHFKM_01742 6.7e-109 fhaB M Rib/alpha-like repeat
ICLLHFKM_01743 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ICLLHFKM_01744 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICLLHFKM_01745 4e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICLLHFKM_01746 4.6e-249 M Glycosyl transferase family group 2
ICLLHFKM_01748 7e-228 aadAT EK Aminotransferase, class I
ICLLHFKM_01749 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ICLLHFKM_01750 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICLLHFKM_01751 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
ICLLHFKM_01752 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ICLLHFKM_01753 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICLLHFKM_01754 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICLLHFKM_01755 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ICLLHFKM_01756 2.6e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICLLHFKM_01757 1e-207 yacL S domain protein
ICLLHFKM_01758 3.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICLLHFKM_01759 3.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
ICLLHFKM_01760 8.5e-50 HA62_12640 S GCN5-related N-acetyl-transferase
ICLLHFKM_01761 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICLLHFKM_01762 1.6e-268 pepC 3.4.22.40 E Peptidase C1-like family
ICLLHFKM_01763 9.6e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
ICLLHFKM_01764 2.6e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICLLHFKM_01765 1.1e-119 tcyB E ABC transporter
ICLLHFKM_01766 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ICLLHFKM_01767 7e-169 I alpha/beta hydrolase fold
ICLLHFKM_01768 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICLLHFKM_01769 0.0 S Bacterial membrane protein, YfhO
ICLLHFKM_01770 2.8e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
ICLLHFKM_01771 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
ICLLHFKM_01773 8.6e-86 ydcK S Belongs to the SprT family
ICLLHFKM_01774 0.0 yhgF K Tex-like protein N-terminal domain protein
ICLLHFKM_01775 6.7e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ICLLHFKM_01776 1.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICLLHFKM_01777 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
ICLLHFKM_01778 2.5e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ICLLHFKM_01779 3.8e-304 aspT P Predicted Permease Membrane Region
ICLLHFKM_01780 1.3e-252 EGP Major facilitator Superfamily
ICLLHFKM_01781 4.3e-115
ICLLHFKM_01784 5.2e-161 yjjH S Calcineurin-like phosphoesterase
ICLLHFKM_01785 1.3e-263 dtpT U amino acid peptide transporter
ICLLHFKM_01786 1.6e-76 tlpA2 L Transposase IS200 like
ICLLHFKM_01787 2.5e-228 L transposase, IS605 OrfB family
ICLLHFKM_01789 8.1e-20 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
ICLLHFKM_01791 6.3e-50 L Belongs to the 'phage' integrase family
ICLLHFKM_01792 3.4e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICLLHFKM_01793 2e-202 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICLLHFKM_01794 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICLLHFKM_01795 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICLLHFKM_01796 1.2e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
ICLLHFKM_01797 1e-78 argR K Regulates arginine biosynthesis genes
ICLLHFKM_01798 2.3e-264 recN L May be involved in recombinational repair of damaged DNA
ICLLHFKM_01799 1.7e-54
ICLLHFKM_01800 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ICLLHFKM_01801 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ICLLHFKM_01802 5.1e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICLLHFKM_01803 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICLLHFKM_01804 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICLLHFKM_01805 2e-255 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICLLHFKM_01806 7.6e-132 stp 3.1.3.16 T phosphatase
ICLLHFKM_01807 0.0 KLT serine threonine protein kinase
ICLLHFKM_01808 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ICLLHFKM_01809 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ICLLHFKM_01810 7.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
ICLLHFKM_01811 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ICLLHFKM_01812 4.7e-58 asp S Asp23 family, cell envelope-related function
ICLLHFKM_01813 0.0 yloV S DAK2 domain fusion protein YloV
ICLLHFKM_01814 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICLLHFKM_01815 7.3e-189 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ICLLHFKM_01816 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICLLHFKM_01817 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ICLLHFKM_01818 0.0 smc D Required for chromosome condensation and partitioning
ICLLHFKM_01819 1.4e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ICLLHFKM_01820 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ICLLHFKM_01821 5.1e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICLLHFKM_01822 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ICLLHFKM_01823 4.1e-40 ylqC S Belongs to the UPF0109 family
ICLLHFKM_01824 3.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICLLHFKM_01825 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ICLLHFKM_01826 6.8e-262 yfnA E amino acid
ICLLHFKM_01827 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ICLLHFKM_01828 1.1e-12 E lipolytic protein G-D-S-L family
ICLLHFKM_01830 3.3e-20
ICLLHFKM_01831 1.5e-36 S Bacteriophage holin family
ICLLHFKM_01832 7.6e-55 S Bacteriophage holin of superfamily 6 (Holin_LLH)
ICLLHFKM_01833 3.1e-193 3.5.1.104 M hydrolase, family 25
ICLLHFKM_01834 1.7e-47 L Belongs to the 'phage' integrase family
ICLLHFKM_01835 4.7e-26 S Phage derived protein Gp49-like (DUF891)
ICLLHFKM_01838 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_01839 1.1e-207 naiP EGP Major facilitator Superfamily
ICLLHFKM_01843 8.1e-55 ntd 2.4.2.6 F Nucleoside
ICLLHFKM_01856 4.6e-84 dck 2.7.1.74 F Deoxynucleoside kinase
ICLLHFKM_01862 2.4e-09 S Hypothetical protein (DUF2513)
ICLLHFKM_01868 2.3e-121 pnuC H nicotinamide mononucleotide transporter
ICLLHFKM_01869 1e-76 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
ICLLHFKM_01871 1.4e-115 recD 3.1.11.5 L Helix-hairpin-helix containing domain
ICLLHFKM_01874 1.3e-101 3.6.4.12 L DnaB-like helicase C terminal domain
ICLLHFKM_01876 5.4e-27
ICLLHFKM_01877 1.2e-59
ICLLHFKM_01878 3.1e-21 L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICLLHFKM_01882 1.1e-06 2.7.1.24 H dephospho-CoA kinase activity
ICLLHFKM_01884 1.8e-21 L Belongs to the 'phage' integrase family
ICLLHFKM_01885 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_01886 3.4e-08
ICLLHFKM_01888 6.1e-12 hol S COG5546 Small integral membrane protein
ICLLHFKM_01891 5.2e-78 xerH L Belongs to the 'phage' integrase family
ICLLHFKM_01892 1.1e-51 D Phage-related minor tail protein
ICLLHFKM_01894 1.4e-49
ICLLHFKM_01895 3.5e-91 S Uncharacterised protein family (UPF0236)
ICLLHFKM_01896 4.5e-26
ICLLHFKM_01897 2.2e-211 M domain protein
ICLLHFKM_01898 7e-218 M domain protein
ICLLHFKM_01899 5.1e-215 S Uncharacterised protein family (UPF0236)
ICLLHFKM_01901 1.5e-26
ICLLHFKM_01903 9.7e-33 L DnaD domain protein
ICLLHFKM_01906 1e-148 S Hydrolases of the alpha beta superfamily
ICLLHFKM_01907 1.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
ICLLHFKM_01908 3.4e-77 ctsR K Belongs to the CtsR family
ICLLHFKM_01909 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ICLLHFKM_01910 1e-110 K Bacterial regulatory proteins, tetR family
ICLLHFKM_01911 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICLLHFKM_01912 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICLLHFKM_01913 1.6e-200 ykiI
ICLLHFKM_01914 2.7e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
ICLLHFKM_01915 5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICLLHFKM_01916 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ICLLHFKM_01917 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICLLHFKM_01918 8e-82 F Belongs to the NrdI family
ICLLHFKM_01919 8e-232 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ICLLHFKM_01920 6.9e-71 rnhA 3.1.26.4 L Ribonuclease HI
ICLLHFKM_01921 1.5e-65 esbA S Family of unknown function (DUF5322)
ICLLHFKM_01922 1.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICLLHFKM_01923 4.8e-176 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICLLHFKM_01924 4.3e-208 carA 6.3.5.5 F Belongs to the CarA family
ICLLHFKM_01925 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICLLHFKM_01926 0.0 FbpA K Fibronectin-binding protein
ICLLHFKM_01927 1.7e-162 degV S EDD domain protein, DegV family
ICLLHFKM_01928 9.4e-94
ICLLHFKM_01929 6.3e-27 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICLLHFKM_01930 4.2e-51 L Transposase IS200 like
ICLLHFKM_01931 5.5e-185 L transposase, IS605 OrfB family
ICLLHFKM_01932 1.8e-40 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
ICLLHFKM_01933 3e-24
ICLLHFKM_01934 1.1e-19 relB L Addiction module antitoxin, RelB DinJ family
ICLLHFKM_01935 7.5e-91 XK27_08850 J Aminoacyl-tRNA editing domain
ICLLHFKM_01936 1e-56 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
ICLLHFKM_01937 7.7e-199 V Beta-lactamase
ICLLHFKM_01938 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ICLLHFKM_01939 1.7e-122 yhiD S MgtC family
ICLLHFKM_01940 4e-121 S GyrI-like small molecule binding domain
ICLLHFKM_01942 1.8e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
ICLLHFKM_01943 3.2e-50 azlD E Branched-chain amino acid transport
ICLLHFKM_01944 7.4e-121 azlC E azaleucine resistance protein AzlC
ICLLHFKM_01945 2.6e-266 K Aminotransferase class I and II
ICLLHFKM_01946 2.7e-304 S amidohydrolase
ICLLHFKM_01947 1.6e-165 S reductase
ICLLHFKM_01948 1.6e-93 2.3.1.183 M Acetyltransferase GNAT family
ICLLHFKM_01949 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ICLLHFKM_01950 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
ICLLHFKM_01951 4.8e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICLLHFKM_01952 0.0 asnB 6.3.5.4 E Asparagine synthase
ICLLHFKM_01953 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ICLLHFKM_01954 1.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICLLHFKM_01955 5e-46 waaB GT4 M Glycosyl transferases group 1
ICLLHFKM_01956 5.8e-160 glf 5.4.99.9 M UDP-galactopyranose mutase
ICLLHFKM_01957 7.8e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ICLLHFKM_01958 8.7e-251 L Transposase IS66 family
ICLLHFKM_01959 8.8e-10 L Transposase IS66 family
ICLLHFKM_01960 2.2e-60 XK27_01125 L PFAM IS66 Orf2 family protein
ICLLHFKM_01962 1.1e-86 V Abi-like protein
ICLLHFKM_01963 7.7e-45
ICLLHFKM_01964 8.1e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
ICLLHFKM_01965 1.9e-248 mmuP E amino acid
ICLLHFKM_01967 6.2e-51 T Toxin-antitoxin system, toxin component, MazF family
ICLLHFKM_01968 4.4e-36
ICLLHFKM_01971 0.0 snf 2.7.11.1 KL domain protein
ICLLHFKM_01972 2e-143 ywqE 3.1.3.48 GM PHP domain protein
ICLLHFKM_01973 2.4e-206 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ICLLHFKM_01974 0.0 sbcC L Putative exonuclease SbcCD, C subunit
ICLLHFKM_01975 8.4e-93 L nuclease
ICLLHFKM_01976 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
ICLLHFKM_01977 5.1e-69
ICLLHFKM_01978 2.2e-102 fic D Fic/DOC family
ICLLHFKM_01979 2.2e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ICLLHFKM_01980 1.5e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
ICLLHFKM_01981 8.4e-31
ICLLHFKM_01982 2.8e-185
ICLLHFKM_01983 1.8e-23
ICLLHFKM_01984 1.6e-243 G Major Facilitator
ICLLHFKM_01985 7.7e-13 G Major Facilitator
ICLLHFKM_01986 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
ICLLHFKM_01987 0.0 M domain protein
ICLLHFKM_01988 2.7e-277 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
ICLLHFKM_01989 1.1e-273 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
ICLLHFKM_01990 2.2e-72
ICLLHFKM_01991 2.6e-112 K Transcriptional regulator, TetR family
ICLLHFKM_01993 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICLLHFKM_01994 1.9e-85
ICLLHFKM_01995 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICLLHFKM_01996 8.1e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICLLHFKM_01997 8.4e-262 nox C NADH oxidase
ICLLHFKM_01998 2e-44 hmpT S ECF-type riboflavin transporter, S component
ICLLHFKM_01999 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
ICLLHFKM_02000 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
ICLLHFKM_02001 5.9e-168 yvgN C Aldo keto reductase
ICLLHFKM_02002 5e-136 puuD S peptidase C26
ICLLHFKM_02003 1.8e-242 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ICLLHFKM_02004 4.2e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
ICLLHFKM_02005 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
ICLLHFKM_02006 6.5e-63 malT G Major Facilitator
ICLLHFKM_02007 2.9e-176 malT G Major Facilitator
ICLLHFKM_02008 6.1e-216 phbA 2.3.1.9 I Belongs to the thiolase family
ICLLHFKM_02009 7.1e-175 malR K Transcriptional regulator, LacI family
ICLLHFKM_02010 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ICLLHFKM_02011 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ICLLHFKM_02012 2.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICLLHFKM_02013 2.3e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
ICLLHFKM_02014 4.6e-202 xerS L Belongs to the 'phage' integrase family
ICLLHFKM_02016 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICLLHFKM_02017 4.2e-77 marR K Transcriptional regulator, MarR family
ICLLHFKM_02018 3.8e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICLLHFKM_02019 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICLLHFKM_02020 1.8e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
ICLLHFKM_02021 1.3e-131 IQ reductase
ICLLHFKM_02022 5.6e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICLLHFKM_02023 2.1e-76 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICLLHFKM_02024 1e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICLLHFKM_02025 3.1e-228 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
ICLLHFKM_02026 6.5e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICLLHFKM_02027 2.2e-82 accA 2.1.3.15, 6.4.1.2 I alpha subunit
ICLLHFKM_02028 9.6e-43 accA 2.1.3.15, 6.4.1.2 I alpha subunit
ICLLHFKM_02029 4.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
ICLLHFKM_02038 6.2e-55
ICLLHFKM_02039 5.1e-116 frnE Q DSBA-like thioredoxin domain
ICLLHFKM_02040 5e-167 I alpha/beta hydrolase fold
ICLLHFKM_02041 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_02053 3.2e-121 L hmm pf00665
ICLLHFKM_02054 1.9e-127 L Helix-turn-helix domain
ICLLHFKM_02055 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
ICLLHFKM_02056 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ICLLHFKM_02057 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ICLLHFKM_02058 4.5e-146 potB P ABC transporter permease
ICLLHFKM_02059 6.5e-140 potC P ABC transporter permease
ICLLHFKM_02060 4.3e-208 potD P ABC transporter
ICLLHFKM_02061 2.4e-229
ICLLHFKM_02062 3e-254 yfnA E Amino Acid
ICLLHFKM_02063 2.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
ICLLHFKM_02064 1.4e-101 gmk2 2.7.4.8 F Guanylate kinase
ICLLHFKM_02065 1.5e-82 zur P Belongs to the Fur family
ICLLHFKM_02066 3.1e-17 3.2.1.14 GH18
ICLLHFKM_02067 5.8e-152
ICLLHFKM_02068 4.9e-38 pspC KT positive regulation of macromolecule biosynthetic process
ICLLHFKM_02069 6e-94 K Transcriptional regulator (TetR family)
ICLLHFKM_02070 2.4e-221 V domain protein
ICLLHFKM_02071 3.9e-84
ICLLHFKM_02072 4.1e-56 L Transposase
ICLLHFKM_02074 8.6e-35 S Transglycosylase associated protein
ICLLHFKM_02075 9.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICLLHFKM_02076 4.2e-126 3.1.3.73 G phosphoglycerate mutase
ICLLHFKM_02077 7.5e-115 dedA S SNARE associated Golgi protein
ICLLHFKM_02078 0.0 helD 3.6.4.12 L DNA helicase
ICLLHFKM_02079 5.1e-243 nox C NADH oxidase
ICLLHFKM_02080 1e-15 nox C NADH oxidase
ICLLHFKM_02081 2.9e-218 nox C NADH oxidase
ICLLHFKM_02082 4.1e-157 EG EamA-like transporter family
ICLLHFKM_02083 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICLLHFKM_02084 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
ICLLHFKM_02085 7.5e-222 S cog cog1373
ICLLHFKM_02087 2.8e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ICLLHFKM_02088 1.1e-223 oxlT P Major Facilitator Superfamily
ICLLHFKM_02089 6.2e-157 spoU 2.1.1.185 J Methyltransferase
ICLLHFKM_02090 3.2e-121 L hmm pf00665
ICLLHFKM_02091 1.9e-127 L Helix-turn-helix domain
ICLLHFKM_02092 3.9e-268 yjeM E Amino Acid
ICLLHFKM_02093 7.8e-236 V MatE
ICLLHFKM_02094 9.3e-71 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
ICLLHFKM_02095 1.5e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICLLHFKM_02096 8.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ICLLHFKM_02097 2.2e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICLLHFKM_02098 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICLLHFKM_02099 1.3e-57 yodB K Transcriptional regulator, HxlR family
ICLLHFKM_02100 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICLLHFKM_02101 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICLLHFKM_02102 6.9e-113 rlpA M PFAM NLP P60 protein
ICLLHFKM_02103 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
ICLLHFKM_02104 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICLLHFKM_02105 4e-71 yneR S Belongs to the HesB IscA family
ICLLHFKM_02106 0.0 S membrane
ICLLHFKM_02107 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
ICLLHFKM_02108 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICLLHFKM_02109 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICLLHFKM_02110 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
ICLLHFKM_02111 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
ICLLHFKM_02112 1.5e-183 glk 2.7.1.2 G Glucokinase
ICLLHFKM_02113 9.1e-68 yqhL P Rhodanese-like protein
ICLLHFKM_02114 3.2e-20 S Protein of unknown function (DUF3042)
ICLLHFKM_02115 1e-178 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICLLHFKM_02116 2.4e-264 glnA 6.3.1.2 E glutamine synthetase
ICLLHFKM_02117 4e-297 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICLLHFKM_02118 1.1e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
ICLLHFKM_02119 3.9e-12
ICLLHFKM_02120 1.3e-156 P Belongs to the nlpA lipoprotein family
ICLLHFKM_02121 7.2e-82 Z012_01130 S Fic/DOC family
ICLLHFKM_02122 5e-64 V HNH endonuclease
ICLLHFKM_02125 1.1e-250 L PFAM transposase, IS4 family protein
ICLLHFKM_02127 1.8e-193 2.7.7.65 T GGDEF domain
ICLLHFKM_02128 1.1e-70
ICLLHFKM_02129 9.8e-239 pgaC GT2 M Glycosyl transferase
ICLLHFKM_02130 3.3e-141 T EAL domain
ICLLHFKM_02132 9e-83 L Integrase
ICLLHFKM_02133 4.3e-23 lytE M Lysin motif
ICLLHFKM_02134 2.9e-82
ICLLHFKM_02135 5e-251 pgaC GT2 M Glycosyl transferase
ICLLHFKM_02136 1.6e-82 T EAL domain
ICLLHFKM_02137 6.3e-46 T EAL domain
ICLLHFKM_02138 1.7e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
ICLLHFKM_02139 1.9e-59 yneR
ICLLHFKM_02140 1.5e-99 qorB 1.6.5.2 GM NmrA-like family
ICLLHFKM_02141 1e-159 akr5f 1.1.1.346 S reductase
ICLLHFKM_02142 5.6e-134 K Transcriptional regulator
ICLLHFKM_02143 4e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
ICLLHFKM_02144 2.3e-155 ypuA S Protein of unknown function (DUF1002)
ICLLHFKM_02145 1.1e-228 aadAT EK Aminotransferase, class I
ICLLHFKM_02146 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICLLHFKM_02147 6e-154 tesE Q hydratase
ICLLHFKM_02148 2.5e-142 S Alpha beta hydrolase
ICLLHFKM_02149 4.5e-82 lacA S transferase hexapeptide repeat
ICLLHFKM_02150 1.6e-56 K Transcriptional regulator
ICLLHFKM_02151 2.2e-229 L transposase, IS605 OrfB family
ICLLHFKM_02152 4.1e-56 L Transposase
ICLLHFKM_02153 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ICLLHFKM_02154 8.9e-104 ypsA S Belongs to the UPF0398 family
ICLLHFKM_02155 7.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ICLLHFKM_02156 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
ICLLHFKM_02157 1.8e-162 EG EamA-like transporter family
ICLLHFKM_02158 3e-125 dnaD L DnaD domain protein
ICLLHFKM_02159 1.7e-85 ypmB S Protein conserved in bacteria
ICLLHFKM_02160 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ICLLHFKM_02161 3.9e-173 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
ICLLHFKM_02162 3e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
ICLLHFKM_02163 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
ICLLHFKM_02164 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ICLLHFKM_02165 1.9e-89 S Protein of unknown function (DUF1440)
ICLLHFKM_02166 0.0 rafA 3.2.1.22 G alpha-galactosidase
ICLLHFKM_02167 2e-191 galR K Periplasmic binding protein-like domain
ICLLHFKM_02168 4.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
ICLLHFKM_02169 6.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICLLHFKM_02170 4.5e-124 lrgB M LrgB-like family
ICLLHFKM_02171 1.9e-66 lrgA S LrgA family
ICLLHFKM_02172 1.1e-130 lytT K response regulator receiver
ICLLHFKM_02173 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
ICLLHFKM_02174 4e-148 f42a O Band 7 protein
ICLLHFKM_02175 1.1e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
ICLLHFKM_02176 6.4e-156 yitU 3.1.3.104 S hydrolase
ICLLHFKM_02177 9.2e-39 S Cytochrome B5
ICLLHFKM_02178 9.8e-115 nreC K PFAM regulatory protein LuxR
ICLLHFKM_02179 1.2e-160 hipB K Helix-turn-helix
ICLLHFKM_02180 2.8e-57 yitW S Iron-sulfur cluster assembly protein
ICLLHFKM_02181 3.9e-270 sufB O assembly protein SufB
ICLLHFKM_02182 9.4e-80 nifU C SUF system FeS assembly protein, NifU family
ICLLHFKM_02183 3.3e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICLLHFKM_02184 7.8e-241 sufD O FeS assembly protein SufD
ICLLHFKM_02185 6.5e-145 sufC O FeS assembly ATPase SufC
ICLLHFKM_02186 1.2e-31 feoA P FeoA domain
ICLLHFKM_02187 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
ICLLHFKM_02188 4.5e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ICLLHFKM_02189 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ICLLHFKM_02190 8.5e-63 ydiI Q Thioesterase superfamily
ICLLHFKM_02191 2.4e-109 yvrI K sigma factor activity
ICLLHFKM_02192 2.1e-200 G Transporter, major facilitator family protein
ICLLHFKM_02193 0.0 S Bacterial membrane protein YfhO
ICLLHFKM_02194 3e-104 T Ion transport 2 domain protein
ICLLHFKM_02195 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
ICLLHFKM_02197 0.0 L PLD-like domain
ICLLHFKM_02198 6.4e-61 mrr L restriction endonuclease
ICLLHFKM_02199 2.4e-151 L restriction endonuclease
ICLLHFKM_02200 9.7e-62 3.1.21.3 V Type I restriction modification DNA specificity domain
ICLLHFKM_02201 1.4e-44 S RelE-like toxin of type II toxin-antitoxin system HigB
ICLLHFKM_02202 2.6e-38 higA K Helix-turn-helix XRE-family like proteins
ICLLHFKM_02203 3.2e-15 hsdS-1 3.1.21.3 L Type I restriction modification DNA specificity domain
ICLLHFKM_02204 4.5e-45 3.1.21.3 V Type I restriction modification DNA specificity domain
ICLLHFKM_02205 8.9e-178 L Belongs to the 'phage' integrase family
ICLLHFKM_02206 3.6e-131 3.1.21.3 L Type I restriction modification DNA specificity domain
ICLLHFKM_02207 4.6e-294 hsdM 2.1.1.72 V type I restriction-modification system
ICLLHFKM_02208 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
ICLLHFKM_02209 6.2e-140 IQ reductase
ICLLHFKM_02210 2.8e-58 yhaI S Protein of unknown function (DUF805)
ICLLHFKM_02211 2.2e-44
ICLLHFKM_02212 2.9e-137 nylA 3.5.1.4 J Belongs to the amidase family
ICLLHFKM_02213 7.2e-198 nylA 3.5.1.4 J Belongs to the amidase family
ICLLHFKM_02214 3.1e-22
ICLLHFKM_02215 4.2e-47
ICLLHFKM_02216 2.2e-96 K Acetyltransferase (GNAT) domain
ICLLHFKM_02217 4.5e-296 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ICLLHFKM_02218 4.8e-233 gntT EG Gluconate
ICLLHFKM_02219 3.3e-85 L PFAM transposase IS200-family protein
ICLLHFKM_02222 2.2e-31
ICLLHFKM_02223 5e-34 S Protein of unknown function (DUF2922)
ICLLHFKM_02224 3.2e-102 L Belongs to the 'phage' integrase family
ICLLHFKM_02226 6.1e-139 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ICLLHFKM_02230 6.8e-09 S Domain of unknown function (DUF5067)
ICLLHFKM_02232 4.1e-127
ICLLHFKM_02233 3.5e-51 entB 3.5.1.19 Q Isochorismatase family
ICLLHFKM_02234 4e-90 K Bacterial regulatory proteins, tetR family
ICLLHFKM_02235 3.5e-71 1.6.5.2 S NADPH-dependent FMN reductase
ICLLHFKM_02236 4.3e-172 L Plasmid pRiA4b ORF-3-like protein
ICLLHFKM_02238 6.6e-44 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
ICLLHFKM_02239 2.9e-58 S Protein of unknown function (DUF3021)
ICLLHFKM_02240 1.2e-71 K LytTr DNA-binding domain
ICLLHFKM_02241 5.5e-142 cylB V ABC-2 type transporter
ICLLHFKM_02242 1.3e-117 cylA V ABC transporter
ICLLHFKM_02243 4.9e-156 L hmm pf00665
ICLLHFKM_02244 1.7e-128 L Helix-turn-helix domain
ICLLHFKM_02246 5.8e-266 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICLLHFKM_02247 5.4e-236
ICLLHFKM_02248 3.1e-300 hsdM 2.1.1.72 V type I restriction-modification system
ICLLHFKM_02249 3.3e-107 3.1.21.3 V Type I restriction modification DNA specificity domain
ICLLHFKM_02250 2.4e-178 L Belongs to the 'phage' integrase family
ICLLHFKM_02251 1.7e-113 3.1.21.3 V Type I restriction modification DNA specificity domain
ICLLHFKM_02252 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
ICLLHFKM_02253 3.9e-08 entB 3.5.1.19 Q Isochorismatase family
ICLLHFKM_02254 1.4e-29
ICLLHFKM_02255 1.1e-07 V CAAX protease self-immunity
ICLLHFKM_02258 1.3e-43 M Prophage endopeptidase tail
ICLLHFKM_02260 1.3e-194 U type IV secretory pathway VirB4
ICLLHFKM_02261 8.4e-29
ICLLHFKM_02263 1.5e-68
ICLLHFKM_02264 6.1e-233 U TraM recognition site of TraD and TraG
ICLLHFKM_02269 8.8e-145 clpB O Belongs to the ClpA ClpB family
ICLLHFKM_02272 5.8e-19 L Transposase
ICLLHFKM_02280 6.2e-196 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICLLHFKM_02281 4.2e-44 waaB GT4 M Glycosyl transferases group 1
ICLLHFKM_02282 1.7e-225 arcD U Amino acid permease
ICLLHFKM_02283 6.8e-262 E Arginine ornithine antiporter
ICLLHFKM_02284 2.7e-79 argR K Regulates arginine biosynthesis genes
ICLLHFKM_02285 4.1e-239 arcA 3.5.3.6 E Arginine
ICLLHFKM_02286 1.1e-197 ampC V Beta-lactamase
ICLLHFKM_02287 9e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
ICLLHFKM_02288 8.1e-308 sprD D Domain of Unknown Function (DUF1542)
ICLLHFKM_02290 2.1e-102 ydeN S Serine hydrolase
ICLLHFKM_02291 3.5e-62 psiE S Phosphate-starvation-inducible E
ICLLHFKM_02292 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICLLHFKM_02294 1.4e-181 S Aldo keto reductase
ICLLHFKM_02295 2.2e-82 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
ICLLHFKM_02296 0.0 L Helicase C-terminal domain protein
ICLLHFKM_02298 4.6e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
ICLLHFKM_02299 3.3e-55 S Sugar efflux transporter for intercellular exchange
ICLLHFKM_02300 3.2e-127
ICLLHFKM_02301 6.4e-131 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ICLLHFKM_02302 0.0 cadA P P-type ATPase
ICLLHFKM_02303 8.5e-226 5.4.2.7 G Metalloenzyme superfamily
ICLLHFKM_02305 9.7e-155 1.6.5.2 GM NAD(P)H-binding
ICLLHFKM_02306 2e-74 K Transcriptional regulator
ICLLHFKM_02307 2.1e-163 proX M ABC transporter, substrate-binding protein, QAT family
ICLLHFKM_02308 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
ICLLHFKM_02309 3.3e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
ICLLHFKM_02310 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ICLLHFKM_02311 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ICLLHFKM_02312 4.8e-232 ndh 1.6.99.3 C NADH dehydrogenase
ICLLHFKM_02313 9.4e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ICLLHFKM_02314 1.2e-122 radC L DNA repair protein
ICLLHFKM_02315 1.7e-179 mreB D cell shape determining protein MreB
ICLLHFKM_02316 5.9e-152 mreC M Involved in formation and maintenance of cell shape
ICLLHFKM_02317 8.7e-93 mreD M rod shape-determining protein MreD
ICLLHFKM_02318 3.2e-102 glnP P ABC transporter permease
ICLLHFKM_02319 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICLLHFKM_02320 1.5e-160 aatB ET ABC transporter substrate-binding protein
ICLLHFKM_02321 6e-230 ymfF S Peptidase M16 inactive domain protein
ICLLHFKM_02322 2.4e-250 ymfH S Peptidase M16
ICLLHFKM_02323 7.4e-141 ymfM S Helix-turn-helix domain
ICLLHFKM_02324 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICLLHFKM_02325 3.4e-233 cinA 3.5.1.42 S Belongs to the CinA family
ICLLHFKM_02326 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICLLHFKM_02327 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
ICLLHFKM_02328 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICLLHFKM_02329 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICLLHFKM_02330 1.8e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ICLLHFKM_02331 1.2e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ICLLHFKM_02332 1.9e-203 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ICLLHFKM_02333 1.5e-29 yajC U Preprotein translocase
ICLLHFKM_02334 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
ICLLHFKM_02335 6.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ICLLHFKM_02336 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICLLHFKM_02337 4.1e-43 yrzL S Belongs to the UPF0297 family
ICLLHFKM_02338 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICLLHFKM_02339 6.1e-48 yrzB S Belongs to the UPF0473 family
ICLLHFKM_02340 1.6e-86 cvpA S Colicin V production protein
ICLLHFKM_02341 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ICLLHFKM_02342 6.1e-54 trxA O Belongs to the thioredoxin family
ICLLHFKM_02343 4.1e-98 yslB S Protein of unknown function (DUF2507)
ICLLHFKM_02344 1.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ICLLHFKM_02345 1.8e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICLLHFKM_02346 3.5e-39 S Phosphoesterase
ICLLHFKM_02347 1.6e-41 S Phosphoesterase
ICLLHFKM_02348 2.7e-76 ykuL S (CBS) domain
ICLLHFKM_02349 1.2e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
ICLLHFKM_02350 6.2e-149 ykuT M mechanosensitive ion channel
ICLLHFKM_02351 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICLLHFKM_02352 1.8e-14
ICLLHFKM_02353 1.2e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICLLHFKM_02354 4.5e-183 ccpA K catabolite control protein A
ICLLHFKM_02355 1.8e-137
ICLLHFKM_02356 3.5e-132 yebC K Transcriptional regulatory protein
ICLLHFKM_02357 2.3e-18 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ICLLHFKM_02358 6.4e-131 agrA K LytTr DNA-binding domain
ICLLHFKM_02359 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICLLHFKM_02360 3.2e-176
ICLLHFKM_02361 7.6e-183 1.6.5.5 C Zinc-binding dehydrogenase
ICLLHFKM_02362 3.8e-257 G PTS system Galactitol-specific IIC component
ICLLHFKM_02363 3.1e-212 EGP Major facilitator Superfamily
ICLLHFKM_02365 5.6e-32 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ICLLHFKM_02366 1.4e-38 L PFAM Integrase catalytic region
ICLLHFKM_02367 1.3e-31 L PFAM Integrase catalytic region
ICLLHFKM_02368 9.7e-26
ICLLHFKM_02369 5.9e-124 M Glycosyltransferase like family 2
ICLLHFKM_02373 6.6e-22
ICLLHFKM_02376 2.8e-17
ICLLHFKM_02378 1.9e-39 S ORF6C domain
ICLLHFKM_02381 2.3e-27
ICLLHFKM_02382 1.4e-37 K Conserved phage C-terminus (Phg_2220_C)
ICLLHFKM_02390 5.3e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICLLHFKM_02391 1.1e-217 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICLLHFKM_02392 3.9e-162 S Psort location CytoplasmicMembrane, score
ICLLHFKM_02393 1.7e-159 yueF S AI-2E family transporter
ICLLHFKM_02394 2.1e-45 S dextransucrase activity
ICLLHFKM_02395 6.4e-55
ICLLHFKM_02399 1.2e-07 L DnaD domain protein
ICLLHFKM_02404 2.9e-08
ICLLHFKM_02407 1.1e-48 S Phage regulatory protein Rha (Phage_pRha)
ICLLHFKM_02408 4.9e-33
ICLLHFKM_02409 2.7e-17 S Helix-turn-helix domain
ICLLHFKM_02410 2.6e-11 K Transcriptional regulator
ICLLHFKM_02411 2.4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
ICLLHFKM_02412 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICLLHFKM_02413 4e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
ICLLHFKM_02414 5.1e-116 yjbH Q Thioredoxin
ICLLHFKM_02415 1.5e-269 pipD E Dipeptidase
ICLLHFKM_02416 3.8e-206 coiA 3.6.4.12 S Competence protein
ICLLHFKM_02417 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ICLLHFKM_02418 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ICLLHFKM_02419 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
ICLLHFKM_02421 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ICLLHFKM_02422 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICLLHFKM_02423 3.1e-193 yeaN P Transporter, major facilitator family protein
ICLLHFKM_02424 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
ICLLHFKM_02425 2.2e-84 nrdI F Belongs to the NrdI family
ICLLHFKM_02426 2.8e-241 yhdP S Transporter associated domain
ICLLHFKM_02427 2.8e-154 ypdB V (ABC) transporter
ICLLHFKM_02428 5.7e-89 GM epimerase
ICLLHFKM_02429 6.1e-91 M1-874 K Domain of unknown function (DUF1836)
ICLLHFKM_02430 6.6e-78 yybA 2.3.1.57 K Transcriptional regulator
ICLLHFKM_02431 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
ICLLHFKM_02432 7.9e-173 S AI-2E family transporter
ICLLHFKM_02433 2e-160 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
ICLLHFKM_02434 2.7e-63
ICLLHFKM_02435 2.1e-49
ICLLHFKM_02436 2.2e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICLLHFKM_02437 3.1e-138 T GHKL domain
ICLLHFKM_02438 1.9e-13 S Double zinc ribbon
ICLLHFKM_02439 9.8e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
ICLLHFKM_02440 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
ICLLHFKM_02441 2.5e-138 IQ KR domain
ICLLHFKM_02442 1.9e-133 S membrane transporter protein
ICLLHFKM_02443 2.7e-97 S ABC-type cobalt transport system, permease component
ICLLHFKM_02444 8.4e-249 cbiO1 S ABC transporter, ATP-binding protein
ICLLHFKM_02445 7e-113 P Cobalt transport protein
ICLLHFKM_02446 1.6e-52 yvlA
ICLLHFKM_02447 0.0 yjcE P Sodium proton antiporter
ICLLHFKM_02448 2.2e-52 ypaA S Protein of unknown function (DUF1304)
ICLLHFKM_02449 3.4e-188 D Alpha beta
ICLLHFKM_02450 1e-72 K Transcriptional regulator
ICLLHFKM_02451 3.5e-160
ICLLHFKM_02452 4.3e-289 mntH P H( )-stimulated, divalent metal cation uptake system
ICLLHFKM_02453 5.5e-36
ICLLHFKM_02454 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICLLHFKM_02456 6.9e-226 yxiO S Vacuole effluxer Atg22 like
ICLLHFKM_02457 9.2e-258 npp S type I phosphodiesterase nucleotide pyrophosphatase
ICLLHFKM_02458 2.9e-241 E amino acid
ICLLHFKM_02459 3.2e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICLLHFKM_02461 3.5e-28 WQ51_00220 K Helix-turn-helix XRE-family like proteins
ICLLHFKM_02462 5.3e-13 S Protein of unknown function (DUF3278)
ICLLHFKM_02463 1.9e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ICLLHFKM_02464 5.6e-193 XK27_09615 S reductase
ICLLHFKM_02465 5.4e-101 nqr 1.5.1.36 S reductase
ICLLHFKM_02467 1.8e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICLLHFKM_02468 6.4e-182 K Transcriptional regulator, LacI family
ICLLHFKM_02469 3.6e-260 G Major Facilitator
ICLLHFKM_02470 7.3e-85 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
ICLLHFKM_02471 9.6e-83 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
ICLLHFKM_02472 1.1e-84 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ICLLHFKM_02473 6.3e-71 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
ICLLHFKM_02474 8.2e-174 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICLLHFKM_02475 9.1e-88 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
ICLLHFKM_02476 6.4e-63 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICLLHFKM_02477 6.2e-78 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ICLLHFKM_02478 1.2e-95 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ICLLHFKM_02479 5.6e-39 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICLLHFKM_02480 5.4e-37 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
ICLLHFKM_02481 1.4e-110 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICLLHFKM_02483 8.4e-130 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICLLHFKM_02484 1.5e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
ICLLHFKM_02485 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICLLHFKM_02486 1.3e-35 ynzC S UPF0291 protein
ICLLHFKM_02487 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
ICLLHFKM_02488 1.6e-117 plsC 2.3.1.51 I Acyltransferase
ICLLHFKM_02489 3.7e-142 yabB 2.1.1.223 L Methyltransferase small domain
ICLLHFKM_02490 5.4e-49 yazA L GIY-YIG catalytic domain protein
ICLLHFKM_02491 5.2e-184 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICLLHFKM_02492 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
ICLLHFKM_02493 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICLLHFKM_02494 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ICLLHFKM_02495 7.4e-95 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ICLLHFKM_02496 6.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ICLLHFKM_02497 3.9e-148 2.3.1.19 K Helix-turn-helix XRE-family like proteins
ICLLHFKM_02498 5.2e-262 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ICLLHFKM_02499 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
ICLLHFKM_02500 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
ICLLHFKM_02501 8.8e-286 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
ICLLHFKM_02502 2e-100 maa 2.3.1.79 S Maltose O-acetyltransferase
ICLLHFKM_02503 2.2e-48 L PFAM Integrase catalytic region
ICLLHFKM_02504 5.7e-48 K Transcriptional regulator
ICLLHFKM_02505 2.2e-91 folT S ECF transporter, substrate-specific component
ICLLHFKM_02506 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
ICLLHFKM_02507 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
ICLLHFKM_02509 8.7e-116 lssY 3.6.1.27 I Acid phosphatase homologues
ICLLHFKM_02510 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
ICLLHFKM_02511 4.2e-231 clcA_2 P Chloride transporter, ClC family
ICLLHFKM_02512 6.5e-119 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ICLLHFKM_02513 4.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICLLHFKM_02514 1.2e-77 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ICLLHFKM_02515 5.6e-50 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ICLLHFKM_02516 1.6e-51
ICLLHFKM_02517 0.0 S SEC-C Motif Domain Protein
ICLLHFKM_02518 2.3e-111 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
ICLLHFKM_02519 3.5e-76
ICLLHFKM_02520 1.2e-177
ICLLHFKM_02521 2.8e-44 L transposase and inactivated derivatives, IS30 family
ICLLHFKM_02522 1.8e-124 L PFAM Integrase catalytic region

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)