ORF_ID e_value Gene_name EC_number CAZy COGs Description
NAFHOKKD_00001 6.8e-190 L Transposase IS66 family
NAFHOKKD_00002 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
NAFHOKKD_00003 3e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NAFHOKKD_00004 3.1e-103 metI P ABC transporter permease
NAFHOKKD_00005 6.1e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NAFHOKKD_00006 3.5e-244 clcA P chloride
NAFHOKKD_00007 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NAFHOKKD_00008 1.9e-102 proW P ABC transporter, permease protein
NAFHOKKD_00009 6.5e-142 proV E ABC transporter, ATP-binding protein
NAFHOKKD_00010 2.4e-108 proWZ P ABC transporter permease
NAFHOKKD_00011 2.5e-161 proX M ABC transporter, substrate-binding protein, QAT family
NAFHOKKD_00012 3.8e-73 K Transcriptional regulator
NAFHOKKD_00013 3.5e-50 1.6.5.2 GM NAD(P)H-binding
NAFHOKKD_00014 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NAFHOKKD_00015 3.1e-116 udk 2.7.1.48 F Cytidine monophosphokinase
NAFHOKKD_00016 2.5e-115 rlpA M PFAM NLP P60 protein
NAFHOKKD_00017 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NAFHOKKD_00018 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NAFHOKKD_00019 6.7e-59 yodB K Transcriptional regulator, HxlR family
NAFHOKKD_00020 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NAFHOKKD_00021 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NAFHOKKD_00022 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NAFHOKKD_00023 1.3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NAFHOKKD_00024 5.6e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NAFHOKKD_00025 1.5e-234 V MatE
NAFHOKKD_00026 1.9e-267 yjeM E Amino Acid
NAFHOKKD_00027 3.4e-37
NAFHOKKD_00028 0.0 ydaO E amino acid
NAFHOKKD_00029 9e-303 ybeC E amino acid
NAFHOKKD_00030 2e-80 S Aminoacyl-tRNA editing domain
NAFHOKKD_00031 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NAFHOKKD_00032 3.7e-221 norA EGP Major facilitator Superfamily
NAFHOKKD_00033 8.9e-41 1.3.5.4 S FMN binding
NAFHOKKD_00034 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NAFHOKKD_00035 1.4e-262 yfnA E amino acid
NAFHOKKD_00036 4.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NAFHOKKD_00038 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NAFHOKKD_00039 0.0 helD 3.6.4.12 L DNA helicase
NAFHOKKD_00040 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
NAFHOKKD_00041 8e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NAFHOKKD_00042 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NAFHOKKD_00043 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NAFHOKKD_00044 1.8e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NAFHOKKD_00045 8.6e-176
NAFHOKKD_00046 1.5e-129 cobB K SIR2 family
NAFHOKKD_00048 6.9e-161 yunF F Protein of unknown function DUF72
NAFHOKKD_00049 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NAFHOKKD_00050 3.5e-154 tatD L hydrolase, TatD family
NAFHOKKD_00051 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NAFHOKKD_00052 9.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NAFHOKKD_00053 6.8e-37 veg S Biofilm formation stimulator VEG
NAFHOKKD_00054 2e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NAFHOKKD_00055 6.4e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
NAFHOKKD_00056 2.2e-122 fhuC P ABC transporter
NAFHOKKD_00057 4.7e-127 znuB U ABC 3 transport family
NAFHOKKD_00058 1.2e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NAFHOKKD_00059 1e-238 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NAFHOKKD_00060 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NAFHOKKD_00061 9e-48
NAFHOKKD_00062 2.1e-146 yxeH S hydrolase
NAFHOKKD_00063 1e-270 ywfO S HD domain protein
NAFHOKKD_00064 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NAFHOKKD_00065 2.4e-15 3.2.1.18 GH33 M Rib/alpha-like repeat
NAFHOKKD_00068 1.2e-76 marR K Transcriptional regulator, MarR family
NAFHOKKD_00069 1.5e-167 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NAFHOKKD_00070 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NAFHOKKD_00071 5.5e-151 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NAFHOKKD_00072 4.5e-124 IQ reductase
NAFHOKKD_00073 1.2e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NAFHOKKD_00074 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NAFHOKKD_00075 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NAFHOKKD_00076 3.4e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NAFHOKKD_00077 8.4e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NAFHOKKD_00078 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NAFHOKKD_00079 1.3e-129 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NAFHOKKD_00088 7.4e-42 L transposase, IS605 OrfB family
NAFHOKKD_00089 2.3e-09 tra L Transposase and inactivated derivatives, IS30 family
NAFHOKKD_00090 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NAFHOKKD_00091 5e-56 L Transposase IS66 family
NAFHOKKD_00092 2.2e-176 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NAFHOKKD_00093 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NAFHOKKD_00095 3.2e-36 dnaG L DNA primase activity
NAFHOKKD_00097 9.7e-13 D Psort location Cellwall, score
NAFHOKKD_00098 2e-107 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NAFHOKKD_00099 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NAFHOKKD_00100 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NAFHOKKD_00101 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NAFHOKKD_00102 4.8e-65 L Transposase
NAFHOKKD_00103 9.7e-123 L Transposase
NAFHOKKD_00105 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NAFHOKKD_00106 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NAFHOKKD_00107 2e-158 htpX O Belongs to the peptidase M48B family
NAFHOKKD_00108 2e-92 lemA S LemA family
NAFHOKKD_00109 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NAFHOKKD_00110 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NAFHOKKD_00111 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NAFHOKKD_00112 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NAFHOKKD_00113 4.2e-160 3.2.1.55 GH51 G Right handed beta helix region
NAFHOKKD_00114 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NAFHOKKD_00115 7.3e-116 srtA 3.4.22.70 M sortase family
NAFHOKKD_00116 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
NAFHOKKD_00117 7.7e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NAFHOKKD_00118 4.6e-41 rpmE2 J Ribosomal protein L31
NAFHOKKD_00119 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NAFHOKKD_00120 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NAFHOKKD_00121 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NAFHOKKD_00122 5.2e-53 ywiB S Domain of unknown function (DUF1934)
NAFHOKKD_00123 2e-264 glnP P ABC transporter
NAFHOKKD_00124 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NAFHOKKD_00125 4.7e-220 cycA E Amino acid permease
NAFHOKKD_00126 5.1e-218 nupG F Nucleoside transporter
NAFHOKKD_00127 7.3e-169 rihC 3.2.2.1 F Nucleoside
NAFHOKKD_00128 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NAFHOKKD_00129 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NAFHOKKD_00130 8.7e-144 noc K Belongs to the ParB family
NAFHOKKD_00131 3.6e-140 soj D Sporulation initiation inhibitor
NAFHOKKD_00132 5e-154 spo0J K Belongs to the ParB family
NAFHOKKD_00133 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
NAFHOKKD_00134 7.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NAFHOKKD_00135 4.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
NAFHOKKD_00136 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NAFHOKKD_00137 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NAFHOKKD_00138 3.2e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NAFHOKKD_00139 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NAFHOKKD_00140 4e-170 deoR K sugar-binding domain protein
NAFHOKKD_00141 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NAFHOKKD_00142 3.8e-125 K response regulator
NAFHOKKD_00143 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
NAFHOKKD_00144 1e-138 azlC E AzlC protein
NAFHOKKD_00145 1.6e-52 azlD S branched-chain amino acid
NAFHOKKD_00146 9.4e-17 K LysR substrate binding domain
NAFHOKKD_00147 4.2e-63 K LysR substrate binding domain
NAFHOKKD_00148 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NAFHOKKD_00149 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NAFHOKKD_00150 0.0 S Bacterial membrane protein, YfhO
NAFHOKKD_00151 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NAFHOKKD_00152 4.5e-168 I alpha/beta hydrolase fold
NAFHOKKD_00153 3.2e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NAFHOKKD_00154 1.4e-119 tcyB E ABC transporter
NAFHOKKD_00155 3.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NAFHOKKD_00156 6.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NAFHOKKD_00157 8.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
NAFHOKKD_00158 1.3e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NAFHOKKD_00159 1.9e-49 HA62_12640 S GCN5-related N-acetyl-transferase
NAFHOKKD_00160 2.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NAFHOKKD_00161 5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NAFHOKKD_00162 4.7e-205 yacL S domain protein
NAFHOKKD_00163 4.7e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NAFHOKKD_00164 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NAFHOKKD_00165 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NAFHOKKD_00166 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NAFHOKKD_00167 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NAFHOKKD_00168 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
NAFHOKKD_00169 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NAFHOKKD_00170 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NAFHOKKD_00171 5.6e-225 aadAT EK Aminotransferase, class I
NAFHOKKD_00172 8.6e-149 M Glycosyl transferase family group 2
NAFHOKKD_00173 1.4e-77 L Helix-turn-helix domain
NAFHOKKD_00174 1.3e-156 L hmm pf00665
NAFHOKKD_00175 3.8e-60 M Glycosyl transferase family group 2
NAFHOKKD_00176 3.8e-38 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NAFHOKKD_00177 7.8e-157 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NAFHOKKD_00178 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NAFHOKKD_00179 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NAFHOKKD_00180 3.4e-48
NAFHOKKD_00182 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NAFHOKKD_00183 2.8e-148 holA 2.7.7.7 L DNA polymerase III delta subunit
NAFHOKKD_00184 0.0 comEC S Competence protein ComEC
NAFHOKKD_00185 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
NAFHOKKD_00186 5.8e-80 comEA L Competence protein ComEA
NAFHOKKD_00187 6.7e-198 ylbL T Belongs to the peptidase S16 family
NAFHOKKD_00188 1.5e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NAFHOKKD_00189 2.1e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NAFHOKKD_00190 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NAFHOKKD_00191 3.2e-220 ftsW D Belongs to the SEDS family
NAFHOKKD_00192 0.0 typA T GTP-binding protein TypA
NAFHOKKD_00193 3.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NAFHOKKD_00194 6.3e-45 yktA S Belongs to the UPF0223 family
NAFHOKKD_00195 2.3e-273 lpdA 1.8.1.4 C Dehydrogenase
NAFHOKKD_00196 1.3e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NAFHOKKD_00197 4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NAFHOKKD_00198 8.8e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NAFHOKKD_00199 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NAFHOKKD_00200 1.8e-78
NAFHOKKD_00201 4.9e-31 ykzG S Belongs to the UPF0356 family
NAFHOKKD_00202 1.1e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NAFHOKKD_00203 5.7e-29
NAFHOKKD_00204 4.7e-128 mltD CBM50 M NlpC P60 family protein
NAFHOKKD_00206 6.5e-57
NAFHOKKD_00207 6.2e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NAFHOKKD_00208 1.1e-218 EG GntP family permease
NAFHOKKD_00209 8.5e-84 KT Putative sugar diacid recognition
NAFHOKKD_00210 1.4e-195 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NAFHOKKD_00211 3e-215 patA 2.6.1.1 E Aminotransferase
NAFHOKKD_00212 8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NAFHOKKD_00213 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NAFHOKKD_00214 5.7e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NAFHOKKD_00215 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NAFHOKKD_00216 2.6e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NAFHOKKD_00217 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NAFHOKKD_00218 3.5e-180 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NAFHOKKD_00219 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NAFHOKKD_00220 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NAFHOKKD_00221 2.9e-117 S Repeat protein
NAFHOKKD_00222 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NAFHOKKD_00223 7.6e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NAFHOKKD_00224 7.5e-58 XK27_04120 S Putative amino acid metabolism
NAFHOKKD_00225 6e-216 iscS 2.8.1.7 E Aminotransferase class V
NAFHOKKD_00226 3.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NAFHOKKD_00228 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NAFHOKKD_00229 4.2e-32 cspA K Cold shock protein
NAFHOKKD_00230 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NAFHOKKD_00231 3e-35 divIVA D DivIVA domain protein
NAFHOKKD_00232 1.7e-145 ylmH S S4 domain protein
NAFHOKKD_00233 1.1e-40 yggT S YGGT family
NAFHOKKD_00234 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NAFHOKKD_00235 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NAFHOKKD_00236 1.1e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NAFHOKKD_00237 3e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NAFHOKKD_00238 2.5e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NAFHOKKD_00239 2.3e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NAFHOKKD_00240 2.2e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NAFHOKKD_00241 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NAFHOKKD_00242 1.3e-55 ftsL D Cell division protein FtsL
NAFHOKKD_00243 2.2e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NAFHOKKD_00244 3.1e-77 mraZ K Belongs to the MraZ family
NAFHOKKD_00245 1.7e-57
NAFHOKKD_00246 1.2e-10 S Protein of unknown function (DUF4044)
NAFHOKKD_00247 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NAFHOKKD_00248 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NAFHOKKD_00249 5.2e-156 rrmA 2.1.1.187 H Methyltransferase
NAFHOKKD_00250 2.1e-180 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NAFHOKKD_00251 6.9e-83 L PFAM transposase IS200-family protein
NAFHOKKD_00261 3.8e-70 yqeY S YqeY-like protein
NAFHOKKD_00262 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NAFHOKKD_00263 1.1e-262 glnPH2 P ABC transporter permease
NAFHOKKD_00264 3.8e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NAFHOKKD_00265 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NAFHOKKD_00266 3.2e-101 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NAFHOKKD_00267 5.7e-161 EG EamA-like transporter family
NAFHOKKD_00268 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NAFHOKKD_00269 1.3e-190 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NAFHOKKD_00270 8.9e-153 KT YcbB domain
NAFHOKKD_00271 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NAFHOKKD_00274 2.2e-28 ebh D nuclear chromosome segregation
NAFHOKKD_00275 2.5e-16 K Cro/C1-type HTH DNA-binding domain
NAFHOKKD_00278 2.2e-09 S zinc-ribbon domain
NAFHOKKD_00279 3.6e-47
NAFHOKKD_00280 3.1e-48 agrA K LytTr DNA-binding domain
NAFHOKKD_00281 1e-59 S Double zinc ribbon
NAFHOKKD_00282 5.8e-186 2.7.13.3 T GHKL domain
NAFHOKKD_00294 8.1e-106 L hmm pf00665
NAFHOKKD_00295 7.9e-34
NAFHOKKD_00296 3.6e-65
NAFHOKKD_00297 2.3e-31
NAFHOKKD_00298 6.3e-67 L Transposase, IS116 IS110 IS902 family
NAFHOKKD_00299 1.8e-26 L Transposase, IS116 IS110 IS902 family
NAFHOKKD_00300 7.8e-132 L Recombinase
NAFHOKKD_00302 3.3e-59 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NAFHOKKD_00303 1.3e-88 M family 8
NAFHOKKD_00304 2.3e-125 L Transposase
NAFHOKKD_00305 1.1e-30 L Transposase
NAFHOKKD_00306 5.7e-97 M family 8
NAFHOKKD_00307 1.4e-181 K Transcriptional regulator, LacI family
NAFHOKKD_00308 4.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NAFHOKKD_00309 3.9e-93
NAFHOKKD_00310 3.6e-25
NAFHOKKD_00311 3.7e-61 asp S Asp23 family, cell envelope-related function
NAFHOKKD_00312 1.2e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NAFHOKKD_00314 5.4e-204 amtB P ammonium transporter
NAFHOKKD_00315 5.2e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NAFHOKKD_00316 4.3e-83 yvbK 3.1.3.25 K GNAT family
NAFHOKKD_00317 1.7e-91
NAFHOKKD_00318 1.6e-120 pnb C nitroreductase
NAFHOKKD_00319 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
NAFHOKKD_00320 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NAFHOKKD_00321 1.5e-66 S Protein of unknown function (DUF3021)
NAFHOKKD_00322 2e-76 K LytTr DNA-binding domain
NAFHOKKD_00323 3.4e-94 K Acetyltransferase (GNAT) family
NAFHOKKD_00324 1.4e-206 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NAFHOKKD_00325 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NAFHOKKD_00326 6.8e-198 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NAFHOKKD_00327 3.9e-143 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NAFHOKKD_00328 5.6e-71
NAFHOKKD_00329 2.4e-101 fic D Fic/DOC family
NAFHOKKD_00330 1.1e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NAFHOKKD_00331 1.4e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NAFHOKKD_00332 1e-31
NAFHOKKD_00333 5.8e-43
NAFHOKKD_00334 5.7e-36
NAFHOKKD_00335 2.1e-24
NAFHOKKD_00337 9.1e-123 O Holliday junction DNA helicase ruvB N-terminus
NAFHOKKD_00338 3.4e-223 O Subtilase family
NAFHOKKD_00339 5.9e-48
NAFHOKKD_00340 6.8e-74 S MTH538 TIR-like domain (DUF1863)
NAFHOKKD_00341 1.7e-30
NAFHOKKD_00342 5.9e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NAFHOKKD_00344 2e-19 QT PucR C-terminal helix-turn-helix domain
NAFHOKKD_00345 2.2e-131 1.6.5.2 GM NAD(P)H-binding
NAFHOKKD_00347 5.5e-29 S Protein of unknown function (DUF4065)
NAFHOKKD_00348 5.8e-88 doc
NAFHOKKD_00349 1.8e-09
NAFHOKKD_00351 1.9e-44
NAFHOKKD_00352 4.7e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NAFHOKKD_00353 1.3e-249 mmuP E amino acid
NAFHOKKD_00355 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NAFHOKKD_00356 2.4e-161 L PFAM Integrase catalytic region
NAFHOKKD_00357 7.7e-129 pnuC H nicotinamide mononucleotide transporter
NAFHOKKD_00358 5e-104 pncA Q Isochorismatase family
NAFHOKKD_00359 6e-266 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NAFHOKKD_00360 1.4e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
NAFHOKKD_00361 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NAFHOKKD_00362 1.2e-176 S Phage capsid family
NAFHOKKD_00363 6.8e-41 S Phage gp6-like head-tail connector protein
NAFHOKKD_00364 3.2e-54 S Phage head-tail joining protein
NAFHOKKD_00365 7.7e-218 L Recombinase zinc beta ribbon domain
NAFHOKKD_00366 7e-46 L Recombinase
NAFHOKKD_00367 2e-69 L Recombinase
NAFHOKKD_00368 8.3e-21 5.1.1.13 M Asp/Glu/Hydantoin racemase
NAFHOKKD_00369 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
NAFHOKKD_00370 6.3e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
NAFHOKKD_00371 5.2e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NAFHOKKD_00372 3.6e-94 dps P Belongs to the Dps family
NAFHOKKD_00373 7.9e-35 copZ C Heavy-metal-associated domain
NAFHOKKD_00374 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NAFHOKKD_00375 5.6e-34
NAFHOKKD_00377 5.3e-112 S Domain of unknown function (DUF4393)
NAFHOKKD_00379 1.6e-13
NAFHOKKD_00382 9.1e-50
NAFHOKKD_00383 3.1e-100 L Belongs to the 'phage' integrase family
NAFHOKKD_00384 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NAFHOKKD_00385 3e-81 F Belongs to the NrdI family
NAFHOKKD_00386 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NAFHOKKD_00387 3.2e-101 ypsA S Belongs to the UPF0398 family
NAFHOKKD_00388 8.3e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NAFHOKKD_00389 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NAFHOKKD_00390 1.3e-160 EG EamA-like transporter family
NAFHOKKD_00391 1.1e-122 dnaD L DnaD domain protein
NAFHOKKD_00392 1.7e-85 ypmB S Protein conserved in bacteria
NAFHOKKD_00393 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NAFHOKKD_00394 5.3e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NAFHOKKD_00395 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NAFHOKKD_00396 3e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NAFHOKKD_00397 3.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NAFHOKKD_00398 1.7e-84 S Protein of unknown function (DUF1440)
NAFHOKKD_00399 3.4e-48
NAFHOKKD_00400 3.4e-28 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NAFHOKKD_00401 2.4e-16 S Domain of unknown function (DUF4767)
NAFHOKKD_00402 1.5e-52
NAFHOKKD_00403 1.5e-118 yrkL S Flavodoxin-like fold
NAFHOKKD_00405 5.9e-64 yeaO S Protein of unknown function, DUF488
NAFHOKKD_00406 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NAFHOKKD_00407 4.4e-203 3.1.3.1 S associated with various cellular activities
NAFHOKKD_00408 6e-233 S Putative metallopeptidase domain
NAFHOKKD_00409 1.4e-47
NAFHOKKD_00410 0.0 pepO 3.4.24.71 O Peptidase family M13
NAFHOKKD_00411 1.4e-105 K Helix-turn-helix XRE-family like proteins
NAFHOKKD_00412 3.9e-87 ymdB S Macro domain protein
NAFHOKKD_00413 2e-195 EGP Major facilitator Superfamily
NAFHOKKD_00414 2.3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NAFHOKKD_00415 3.1e-30 K helix_turn_helix, mercury resistance
NAFHOKKD_00416 6.2e-10 K helix_turn_helix, mercury resistance
NAFHOKKD_00417 1.4e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NAFHOKKD_00418 2.2e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NAFHOKKD_00419 0.0 ysaB V FtsX-like permease family
NAFHOKKD_00420 8.3e-134 macB2 V ABC transporter, ATP-binding protein
NAFHOKKD_00421 1.9e-178 T PhoQ Sensor
NAFHOKKD_00422 1.2e-123 K response regulator
NAFHOKKD_00423 1.1e-155 ytbE 1.1.1.346 S Aldo keto reductase
NAFHOKKD_00424 2.9e-134 pnuC H nicotinamide mononucleotide transporter
NAFHOKKD_00425 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NAFHOKKD_00426 5.3e-201
NAFHOKKD_00427 2e-52
NAFHOKKD_00428 9.1e-36
NAFHOKKD_00429 1.5e-91 yxkA S Phosphatidylethanolamine-binding protein
NAFHOKKD_00430 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
NAFHOKKD_00431 4.1e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NAFHOKKD_00432 1.1e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NAFHOKKD_00433 5.3e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NAFHOKKD_00434 5e-179 galR K Transcriptional regulator
NAFHOKKD_00436 2.4e-80 topB 5.99.1.2 L Bacterial DNA topoisomerase I DNA-binding domain
NAFHOKKD_00437 3e-36 xerD L Phage integrase, N-terminal SAM-like domain
NAFHOKKD_00446 5.6e-229 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NAFHOKKD_00447 5.4e-77 U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NAFHOKKD_00449 5.2e-52 D nuclear chromosome segregation
NAFHOKKD_00450 3.6e-15
NAFHOKKD_00451 7.1e-15 L helicase
NAFHOKKD_00455 1.3e-15
NAFHOKKD_00457 8.6e-37
NAFHOKKD_00458 2.6e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NAFHOKKD_00459 5.6e-13 K prlF antitoxin for toxin YhaV_toxin
NAFHOKKD_00466 3.9e-18 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NAFHOKKD_00468 3.6e-247 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NAFHOKKD_00469 1.7e-84 L Integrase
NAFHOKKD_00470 1.2e-118 ybhL S Belongs to the BI1 family
NAFHOKKD_00471 4.2e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NAFHOKKD_00472 4.3e-194 S Protein of unknown function (DUF3114)
NAFHOKKD_00473 1.8e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NAFHOKKD_00474 2.9e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NAFHOKKD_00475 1.2e-105 yvdD 3.2.2.10 S Belongs to the LOG family
NAFHOKKD_00476 9.1e-62 S Domain of unknown function (DUF4828)
NAFHOKKD_00477 1.7e-190 mocA S Oxidoreductase
NAFHOKKD_00478 1.9e-231 yfmL L DEAD DEAH box helicase
NAFHOKKD_00480 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NAFHOKKD_00481 3.6e-31
NAFHOKKD_00482 5.8e-16
NAFHOKKD_00483 1.3e-67 gtcA S Teichoic acid glycosylation protein
NAFHOKKD_00484 6.1e-79 fld C Flavodoxin
NAFHOKKD_00485 8.5e-167 map 3.4.11.18 E Methionine Aminopeptidase
NAFHOKKD_00486 4.3e-219 arcT 2.6.1.1 E Aminotransferase
NAFHOKKD_00487 3.1e-254 E Arginine ornithine antiporter
NAFHOKKD_00488 9e-281 yjeM E Amino Acid
NAFHOKKD_00489 4e-151 yihY S Belongs to the UPF0761 family
NAFHOKKD_00490 5e-34 S Protein of unknown function (DUF2922)
NAFHOKKD_00491 1.4e-30
NAFHOKKD_00492 3.4e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
NAFHOKKD_00493 4.3e-146 cps1D M Domain of unknown function (DUF4422)
NAFHOKKD_00494 1.7e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NAFHOKKD_00495 8.5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
NAFHOKKD_00496 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
NAFHOKKD_00497 1.4e-215 cps3F
NAFHOKKD_00498 8.3e-103 M biosynthesis protein
NAFHOKKD_00499 1.4e-259 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NAFHOKKD_00500 1e-198 waaB GT4 M Glycosyl transferases group 1
NAFHOKKD_00501 1.5e-191 M transferase activity, transferring glycosyl groups
NAFHOKKD_00502 1.2e-194 S enterobacterial common antigen metabolic process
NAFHOKKD_00503 3.6e-125 acmD M repeat protein
NAFHOKKD_00504 3.2e-07 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NAFHOKKD_00505 1.1e-130 O Bacterial dnaA protein
NAFHOKKD_00506 3.4e-32 spoIVFA GT2,GT4 D peptidase
NAFHOKKD_00509 7.5e-25 S GDSL-like Lipase/Acylhydrolase
NAFHOKKD_00510 2.1e-69
NAFHOKKD_00512 1.7e-41
NAFHOKKD_00513 1.4e-40 hol S COG5546 Small integral membrane protein
NAFHOKKD_00514 8.4e-88 3.5.1.28 M Glycosyl hydrolases family 25
NAFHOKKD_00516 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
NAFHOKKD_00517 5.6e-65 esbA S Family of unknown function (DUF5322)
NAFHOKKD_00518 3.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NAFHOKKD_00519 4.9e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NAFHOKKD_00520 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
NAFHOKKD_00521 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NAFHOKKD_00522 0.0 FbpA K Fibronectin-binding protein
NAFHOKKD_00523 7.7e-158 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NAFHOKKD_00524 5.5e-161 degV S EDD domain protein, DegV family
NAFHOKKD_00525 5.1e-90
NAFHOKKD_00526 1.2e-117 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NAFHOKKD_00527 1.8e-156 gspA M family 8
NAFHOKKD_00528 2.8e-154 S Alpha beta hydrolase
NAFHOKKD_00529 1.5e-94 K Acetyltransferase (GNAT) domain
NAFHOKKD_00530 9.6e-198 XK27_08635 S UPF0210 protein
NAFHOKKD_00531 5.7e-166 1.1.1.346 C Aldo keto reductase
NAFHOKKD_00532 1.4e-139 K LysR substrate binding domain protein
NAFHOKKD_00533 5.2e-81 C Flavodoxin
NAFHOKKD_00534 1.4e-77 yphH S Cupin domain
NAFHOKKD_00535 1.7e-73 yeaL S UPF0756 membrane protein
NAFHOKKD_00536 1.1e-196 EGP Major facilitator Superfamily
NAFHOKKD_00537 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_00538 2.1e-63
NAFHOKKD_00541 2e-18 D nuclear chromosome segregation
NAFHOKKD_00547 1e-229 V N-6 DNA Methylase
NAFHOKKD_00548 1.4e-47 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
NAFHOKKD_00549 1.3e-91 L Belongs to the 'phage' integrase family
NAFHOKKD_00550 4.5e-24 sspC 2.7.7.7 DM Glucan-binding protein C
NAFHOKKD_00551 4.8e-12 D Psort location Cellwall, score
NAFHOKKD_00552 5.3e-33 XK27_00515 D Glucan-binding protein C
NAFHOKKD_00553 8.7e-15 K ORF6N domain
NAFHOKKD_00556 1e-08 nrdH O Glutaredoxin-like protein NrdH
NAFHOKKD_00557 1.6e-51 L Protein of unknown function (DUF3991)
NAFHOKKD_00558 1.3e-09 yvaO K transcriptional
NAFHOKKD_00559 7.8e-142 topA2 5.99.1.2 G Topoisomerase IA
NAFHOKKD_00562 1.1e-144 clpB O Belongs to the ClpA ClpB family
NAFHOKKD_00567 4e-232 U TraM recognition site of TraD and TraG
NAFHOKKD_00568 1.2e-68
NAFHOKKD_00570 2.2e-29
NAFHOKKD_00571 3.7e-194 U type IV secretory pathway VirB4
NAFHOKKD_00573 1.3e-43 M Prophage endopeptidase tail
NAFHOKKD_00576 2.9e-08 V CAAX protease self-immunity
NAFHOKKD_00577 2.5e-29
NAFHOKKD_00580 2.2e-50 E Filamentation induced by cAMP protein fic
NAFHOKKD_00581 6.6e-78 S Fic/DOC family
NAFHOKKD_00582 1.4e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NAFHOKKD_00583 4.8e-51 S Iron-sulfur cluster assembly protein
NAFHOKKD_00584 2.6e-150
NAFHOKKD_00585 3.3e-181
NAFHOKKD_00586 1.8e-84 dut S Protein conserved in bacteria
NAFHOKKD_00590 2.1e-103 K Transcriptional regulator
NAFHOKKD_00591 8.2e-73
NAFHOKKD_00592 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NAFHOKKD_00593 5.3e-131 ponA V Beta-lactamase enzyme family
NAFHOKKD_00594 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NAFHOKKD_00595 3.7e-174 uhpT EGP Major facilitator Superfamily
NAFHOKKD_00596 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_00597 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NAFHOKKD_00598 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
NAFHOKKD_00599 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NAFHOKKD_00600 3.1e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NAFHOKKD_00601 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NAFHOKKD_00602 9.3e-164 S Tetratricopeptide repeat
NAFHOKKD_00603 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NAFHOKKD_00604 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NAFHOKKD_00605 1.9e-34 rpsT J Binds directly to 16S ribosomal RNA
NAFHOKKD_00606 0.0 pacL 3.6.3.8 P P-type ATPase
NAFHOKKD_00607 3.4e-85 dps P Belongs to the Dps family
NAFHOKKD_00608 4.6e-52 yagE E amino acid
NAFHOKKD_00609 9.9e-71 yagE E amino acid
NAFHOKKD_00610 1.7e-97 yagE E amino acid
NAFHOKKD_00611 3.7e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NAFHOKKD_00612 2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NAFHOKKD_00613 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NAFHOKKD_00614 5.8e-60 S Double zinc ribbon
NAFHOKKD_00615 1.4e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NAFHOKKD_00616 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
NAFHOKKD_00617 6.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NAFHOKKD_00618 6.3e-37 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NAFHOKKD_00619 2.7e-165 yniA G Phosphotransferase enzyme family
NAFHOKKD_00620 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NAFHOKKD_00621 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NAFHOKKD_00622 8.5e-51
NAFHOKKD_00623 1.7e-126 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NAFHOKKD_00624 6.3e-179 prmA J Ribosomal protein L11 methyltransferase
NAFHOKKD_00625 7.5e-58
NAFHOKKD_00626 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NAFHOKKD_00628 2.3e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NAFHOKKD_00629 1.2e-49 pipD E Dipeptidase
NAFHOKKD_00630 6.3e-215 pipD E Dipeptidase
NAFHOKKD_00631 3.8e-50 L Psort location Cytoplasmic, score
NAFHOKKD_00632 7.4e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NAFHOKKD_00633 2.2e-32 S dextransucrase activity
NAFHOKKD_00634 9.8e-135 L Transposase
NAFHOKKD_00635 8.3e-150 L Helix-turn-helix domain
NAFHOKKD_00636 1.2e-95 L Integrase
NAFHOKKD_00637 2e-53 S Phage derived protein Gp49-like (DUF891)
NAFHOKKD_00638 9.1e-38 K Helix-turn-helix domain
NAFHOKKD_00640 5.1e-221
NAFHOKKD_00641 3.6e-08
NAFHOKKD_00643 2.4e-15
NAFHOKKD_00644 7.3e-71
NAFHOKKD_00646 1.4e-58 rusA L Endodeoxyribonuclease RusA
NAFHOKKD_00647 2.4e-21
NAFHOKKD_00648 3.9e-24
NAFHOKKD_00651 3.7e-58 dnaC 3.4.21.53 L IstB-like ATP binding protein
NAFHOKKD_00652 6.7e-27
NAFHOKKD_00653 3e-15 L Single-strand binding protein family
NAFHOKKD_00654 9.1e-52 S ERF superfamily
NAFHOKKD_00658 8.6e-26 S Uncharacterized protein conserved in bacteria (DUF2188)
NAFHOKKD_00659 1e-13
NAFHOKKD_00664 2.2e-137 K BRO family, N-terminal domain
NAFHOKKD_00665 6.5e-31 K Helix-turn-helix XRE-family like proteins
NAFHOKKD_00666 3e-47 3.4.21.88 K Helix-turn-helix domain
NAFHOKKD_00667 4.6e-70 S Pfam:DUF955
NAFHOKKD_00668 2.8e-126 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NAFHOKKD_00669 5e-311 cadA P P-type ATPase
NAFHOKKD_00670 2.4e-220 5.4.2.7 G Metalloenzyme superfamily
NAFHOKKD_00672 1e-117
NAFHOKKD_00673 2.6e-52 S Sugar efflux transporter for intercellular exchange
NAFHOKKD_00674 2.5e-245 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NAFHOKKD_00676 0.0 L Helicase C-terminal domain protein
NAFHOKKD_00677 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
NAFHOKKD_00678 1.8e-178 S Aldo keto reductase
NAFHOKKD_00680 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NAFHOKKD_00681 2.9e-27 psiE S Phosphate-starvation-inducible E
NAFHOKKD_00682 5.3e-98 ydeN S Serine hydrolase
NAFHOKKD_00684 3.8e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NAFHOKKD_00685 1.2e-253 nhaC C Na H antiporter NhaC
NAFHOKKD_00686 1e-37 S Cytochrome b5-like Heme/Steroid binding domain
NAFHOKKD_00687 7e-113 ywnB S NAD(P)H-binding
NAFHOKKD_00688 2e-35
NAFHOKKD_00689 3.3e-127 IQ Dehydrogenase reductase
NAFHOKKD_00690 5.7e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NAFHOKKD_00691 3.2e-125 L Transposase
NAFHOKKD_00692 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_00698 1.1e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NAFHOKKD_00699 1.5e-275 lysP E amino acid
NAFHOKKD_00700 1.9e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
NAFHOKKD_00701 1.3e-117 lssY 3.6.1.27 I phosphatase
NAFHOKKD_00702 1e-81 S Threonine/Serine exporter, ThrE
NAFHOKKD_00703 2e-127 thrE S Putative threonine/serine exporter
NAFHOKKD_00704 1e-30 cspC K Cold shock protein
NAFHOKKD_00705 5.9e-123 sirR K iron dependent repressor
NAFHOKKD_00706 1.5e-164 czcD P cation diffusion facilitator family transporter
NAFHOKKD_00707 4.2e-116 S membrane
NAFHOKKD_00708 8.4e-109 S VIT family
NAFHOKKD_00709 5.5e-83 usp1 T Belongs to the universal stress protein A family
NAFHOKKD_00710 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NAFHOKKD_00711 9.7e-152 glnH ET ABC transporter
NAFHOKKD_00712 2.4e-110 gluC P ABC transporter permease
NAFHOKKD_00713 3.6e-109 glnP P ABC transporter permease
NAFHOKKD_00714 8.3e-221 S CAAX protease self-immunity
NAFHOKKD_00715 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NAFHOKKD_00716 2.9e-57
NAFHOKKD_00717 2.6e-74 merR K MerR HTH family regulatory protein
NAFHOKKD_00718 7.2e-270 lmrB EGP Major facilitator Superfamily
NAFHOKKD_00719 5.8e-124 S Domain of unknown function (DUF4811)
NAFHOKKD_00720 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NAFHOKKD_00722 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NAFHOKKD_00723 5.4e-92 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NAFHOKKD_00724 7.7e-188 I Alpha beta
NAFHOKKD_00725 3.2e-270 emrY EGP Major facilitator Superfamily
NAFHOKKD_00726 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
NAFHOKKD_00727 9.4e-253 yjjP S Putative threonine/serine exporter
NAFHOKKD_00728 1e-159 mleR K LysR family
NAFHOKKD_00729 4.2e-112 ydjP I Alpha/beta hydrolase family
NAFHOKKD_00730 1.3e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NAFHOKKD_00731 1.6e-272 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NAFHOKKD_00732 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NAFHOKKD_00733 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
NAFHOKKD_00734 2.2e-148 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NAFHOKKD_00735 1e-175 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
NAFHOKKD_00736 8.8e-125 citR K sugar-binding domain protein
NAFHOKKD_00737 1.2e-173 citP P Sodium:sulfate symporter transmembrane region
NAFHOKKD_00738 6.9e-130 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NAFHOKKD_00739 2.4e-267 frdC 1.3.5.4 C FAD binding domain
NAFHOKKD_00740 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NAFHOKKD_00741 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NAFHOKKD_00742 4.3e-158 mleR K LysR family
NAFHOKKD_00743 3.3e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NAFHOKKD_00744 1.5e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NAFHOKKD_00745 3.2e-287 L PFAM plasmid pRiA4b ORF-3 family protein
NAFHOKKD_00746 5.5e-158 L transposase, IS605 OrfB family
NAFHOKKD_00747 4.8e-10 K Helix-turn-helix XRE-family like proteins
NAFHOKKD_00749 2e-133 L Belongs to the 'phage' integrase family
NAFHOKKD_00750 2.5e-88
NAFHOKKD_00751 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NAFHOKKD_00752 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NAFHOKKD_00753 1.6e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NAFHOKKD_00754 9.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NAFHOKKD_00755 5.2e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NAFHOKKD_00756 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NAFHOKKD_00757 7.6e-09
NAFHOKKD_00759 4.2e-57 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NAFHOKKD_00760 6e-131 S Putative HNHc nuclease
NAFHOKKD_00761 3e-138 L Psort location Cytoplasmic, score
NAFHOKKD_00769 4.7e-44
NAFHOKKD_00772 1.2e-20
NAFHOKKD_00773 5.6e-35
NAFHOKKD_00774 2.7e-79 rusA L Endodeoxyribonuclease RusA
NAFHOKKD_00782 6.3e-137
NAFHOKKD_00788 2.6e-84 S nucleoside kinase activity
NAFHOKKD_00793 1.9e-74 S Transcriptional regulator, RinA family
NAFHOKKD_00795 0.0
NAFHOKKD_00796 8.8e-93 S LemA family
NAFHOKKD_00797 8.9e-128
NAFHOKKD_00808 1.2e-132 pnuC H nicotinamide mononucleotide transporter
NAFHOKKD_00810 2.2e-56
NAFHOKKD_00825 7.1e-53 L HNH nucleases
NAFHOKKD_00826 4.2e-80 L Phage terminase, small subunit
NAFHOKKD_00827 5.6e-269 S Phage Terminase
NAFHOKKD_00828 2.9e-145 S portal protein
NAFHOKKD_00829 5.1e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NAFHOKKD_00830 1.5e-131 S Phage capsid family
NAFHOKKD_00831 6.3e-44 S Phage gp6-like head-tail connector protein
NAFHOKKD_00832 9e-38 S Phage head-tail joining protein
NAFHOKKD_00833 3.3e-21
NAFHOKKD_00834 1.3e-24
NAFHOKKD_00835 2.4e-66 S Phage tail tube protein
NAFHOKKD_00836 4e-18
NAFHOKKD_00837 0.0 M Phage tail tape measure protein TP901
NAFHOKKD_00838 1.8e-113 S Phage tail protein
NAFHOKKD_00839 3.2e-203 M Prophage endopeptidase tail
NAFHOKKD_00840 3.2e-54 hol S COG5546 Small integral membrane protein
NAFHOKKD_00841 5.2e-32
NAFHOKKD_00845 9.1e-113
NAFHOKKD_00846 1.1e-31 S GDSL-like Lipase/Acylhydrolase
NAFHOKKD_00849 4.7e-14 tcdA2 GT2,GT4 LM gp58-like protein
NAFHOKKD_00850 1.2e-284 spr M Prophage endopeptidase tail
NAFHOKKD_00851 4.5e-136 S Phage tail protein
NAFHOKKD_00852 0.0 M Phage tail tape measure protein TP901
NAFHOKKD_00853 2.1e-59 S Phage tail assembly chaperone proteins, TAC
NAFHOKKD_00854 7.8e-134 S Phage tail tube protein
NAFHOKKD_00855 1.3e-66 S Protein of unknown function (DUF806)
NAFHOKKD_00856 2.1e-70 S Bacteriophage HK97-gp10, putative tail-component
NAFHOKKD_00857 2e-58 S Phage head-tail joining protein
NAFHOKKD_00858 4.3e-43 S Phage gp6-like head-tail connector protein
NAFHOKKD_00859 5.9e-166 S Phage capsid family
NAFHOKKD_00860 1.7e-67 S Clp protease
NAFHOKKD_00861 2.7e-195 S Phage portal protein
NAFHOKKD_00863 0.0 S Phage Terminase
NAFHOKKD_00864 1.9e-09
NAFHOKKD_00866 7.2e-83 L Phage terminase, small subunit
NAFHOKKD_00867 6.4e-81 L HNH nucleases
NAFHOKKD_00868 1.4e-83 arpU S Phage transcriptional regulator, ArpU family
NAFHOKKD_00872 9.6e-70 XK27_00160 S Domain of unknown function (DUF5052)
NAFHOKKD_00880 1.8e-133
NAFHOKKD_00881 3.1e-69
NAFHOKKD_00883 9e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NAFHOKKD_00884 7.6e-117 L Belongs to the 'phage' integrase family
NAFHOKKD_00885 1.8e-41 L Belongs to the 'phage' integrase family
NAFHOKKD_00886 3.8e-109 L DnaD domain protein
NAFHOKKD_00889 1.7e-19
NAFHOKKD_00891 9.5e-19
NAFHOKKD_00892 1.4e-26 ps115 K Helix-turn-helix XRE-family like proteins
NAFHOKKD_00893 6e-20 E Zn peptidase
NAFHOKKD_00894 1.1e-09
NAFHOKKD_00895 7.7e-54 kch J Ion transport protein
NAFHOKKD_00897 2.6e-08
NAFHOKKD_00898 9e-113 L Belongs to the 'phage' integrase family
NAFHOKKD_00900 4.8e-10 K Helix-turn-helix XRE-family like proteins
NAFHOKKD_00902 2e-133 L Belongs to the 'phage' integrase family
NAFHOKKD_00903 3.2e-54 hol S COG5546 Small integral membrane protein
NAFHOKKD_00904 5.2e-32
NAFHOKKD_00908 9.1e-113
NAFHOKKD_00909 1.1e-31 S GDSL-like Lipase/Acylhydrolase
NAFHOKKD_00912 1.2e-14 S Phage minor structural protein
NAFHOKKD_00916 1.1e-31 S GDSL-like Lipase/Acylhydrolase
NAFHOKKD_00917 9.1e-113
NAFHOKKD_00921 5.2e-32
NAFHOKKD_00922 3.2e-54 hol S COG5546 Small integral membrane protein
NAFHOKKD_00923 1.3e-173 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NAFHOKKD_00924 5.1e-27
NAFHOKKD_00925 1.5e-45 S Phage regulatory protein Rha (Phage_pRha)
NAFHOKKD_00928 1.9e-07
NAFHOKKD_00931 8.9e-09 L DnaD domain protein
NAFHOKKD_00933 2.8e-64
NAFHOKKD_00935 1.3e-55
NAFHOKKD_00936 2.9e-165 GK ROK family
NAFHOKKD_00937 3.4e-239 brnQ U Component of the transport system for branched-chain amino acids
NAFHOKKD_00938 6.1e-137 aroD S Serine hydrolase (FSH1)
NAFHOKKD_00939 4.2e-79 yagE E amino acid
NAFHOKKD_00940 1.4e-145 yagE E amino acid
NAFHOKKD_00941 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NAFHOKKD_00942 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
NAFHOKKD_00943 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NAFHOKKD_00944 2.6e-269 pipD E Dipeptidase
NAFHOKKD_00945 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
NAFHOKKD_00946 0.0 yfiC V ABC transporter
NAFHOKKD_00947 9.8e-287 lmrA V ABC transporter, ATP-binding protein
NAFHOKKD_00948 1.7e-17 K Winged helix DNA-binding domain
NAFHOKKD_00949 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NAFHOKKD_00950 2.9e-19 S PFAM Archaeal ATPase
NAFHOKKD_00951 3.9e-237 L Transposase
NAFHOKKD_00953 1.1e-110 lssY 3.6.1.27 I Acid phosphatase homologues
NAFHOKKD_00954 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NAFHOKKD_00955 3.4e-117 L PFAM transposase IS116 IS110 IS902
NAFHOKKD_00956 5.7e-228 clcA_2 P Chloride transporter, ClC family
NAFHOKKD_00957 1.2e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NAFHOKKD_00958 8.6e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NAFHOKKD_00959 5.1e-111 yjbM 2.7.6.5 S RelA SpoT domain protein
NAFHOKKD_00960 3.1e-113 yjbH Q Thioredoxin
NAFHOKKD_00961 1.6e-260 pipD E Dipeptidase
NAFHOKKD_00962 9.5e-197 coiA 3.6.4.12 S Competence protein
NAFHOKKD_00963 5.7e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NAFHOKKD_00964 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NAFHOKKD_00965 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_00966 3.7e-58 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NAFHOKKD_00967 1.8e-31
NAFHOKKD_00968 2.7e-109 S CAAX protease self-immunity
NAFHOKKD_00969 1.9e-43
NAFHOKKD_00971 5.9e-67
NAFHOKKD_00972 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NAFHOKKD_00973 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NAFHOKKD_00974 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NAFHOKKD_00975 1.8e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NAFHOKKD_00976 5.4e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NAFHOKKD_00977 2.8e-213 folP 2.5.1.15 H dihydropteroate synthase
NAFHOKKD_00978 6.7e-43
NAFHOKKD_00979 4.8e-39
NAFHOKKD_00981 4.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NAFHOKKD_00982 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NAFHOKKD_00983 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NAFHOKKD_00984 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NAFHOKKD_00985 9.4e-38 yheA S Belongs to the UPF0342 family
NAFHOKKD_00986 4.8e-221 yhaO L Ser Thr phosphatase family protein
NAFHOKKD_00987 0.0 L AAA domain
NAFHOKKD_00988 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NAFHOKKD_00990 3.2e-77 hit FG histidine triad
NAFHOKKD_00991 3.9e-136 ecsA V ABC transporter, ATP-binding protein
NAFHOKKD_00992 7.8e-219 ecsB U ABC transporter
NAFHOKKD_00993 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NAFHOKKD_00994 8.2e-23 S YSIRK type signal peptide
NAFHOKKD_00995 1.8e-264 L PFAM Integrase catalytic region
NAFHOKKD_00996 6.2e-67 rmaI K Transcriptional regulator
NAFHOKKD_00997 3.5e-90 yaaU EGP Major facilitator Superfamily
NAFHOKKD_00998 2.5e-49 EGP Major facilitator Superfamily
NAFHOKKD_00999 6e-62 EGP Major facilitator Superfamily
NAFHOKKD_01000 5e-108 yvyE 3.4.13.9 S YigZ family
NAFHOKKD_01001 2.8e-249 comFA L Helicase C-terminal domain protein
NAFHOKKD_01002 1.1e-93 comFC S Competence protein
NAFHOKKD_01003 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NAFHOKKD_01004 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NAFHOKKD_01005 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NAFHOKKD_01006 7.7e-31 KT PspC domain protein
NAFHOKKD_01007 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NAFHOKKD_01008 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NAFHOKKD_01009 9.4e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NAFHOKKD_01010 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NAFHOKKD_01011 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NAFHOKKD_01012 4.6e-137 yrjD S LUD domain
NAFHOKKD_01013 5e-292 lutB C 4Fe-4S dicluster domain
NAFHOKKD_01014 2.7e-168 lutA C Cysteine-rich domain
NAFHOKKD_01015 1.7e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NAFHOKKD_01016 2.2e-48 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NAFHOKKD_01017 2e-147 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NAFHOKKD_01018 1.4e-161 aatB ET PFAM extracellular solute-binding protein, family 3
NAFHOKKD_01019 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
NAFHOKKD_01020 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NAFHOKKD_01021 5.1e-116 yfbR S HD containing hydrolase-like enzyme
NAFHOKKD_01022 1.5e-13
NAFHOKKD_01023 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NAFHOKKD_01024 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NAFHOKKD_01025 3.2e-245 steT E amino acid
NAFHOKKD_01026 1.7e-162 rapZ S Displays ATPase and GTPase activities
NAFHOKKD_01027 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NAFHOKKD_01028 1.5e-169 whiA K May be required for sporulation
NAFHOKKD_01030 8.8e-15
NAFHOKKD_01031 7.6e-71 glpT G Major Facilitator Superfamily
NAFHOKKD_01032 2.9e-103 glpT G Major Facilitator Superfamily
NAFHOKKD_01033 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NAFHOKKD_01035 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NAFHOKKD_01036 1.7e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NAFHOKKD_01037 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NAFHOKKD_01038 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NAFHOKKD_01039 4.7e-244 yifK E Amino acid permease
NAFHOKKD_01040 5.8e-291 clcA P chloride
NAFHOKKD_01041 1.8e-34 secG U Preprotein translocase
NAFHOKKD_01042 5.9e-143 est 3.1.1.1 S Serine aminopeptidase, S33
NAFHOKKD_01043 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NAFHOKKD_01044 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NAFHOKKD_01045 3.9e-237 L Transposase
NAFHOKKD_01046 1.1e-29 S Alpha/beta hydrolase of unknown function (DUF915)
NAFHOKKD_01047 4.4e-112 yviA S Protein of unknown function (DUF421)
NAFHOKKD_01048 4.3e-36 S Protein of unknown function (DUF3290)
NAFHOKKD_01049 4.1e-144 ywqE 3.1.3.48 GM PHP domain protein
NAFHOKKD_01050 0.0 snf 2.7.11.1 KL domain protein
NAFHOKKD_01052 8.9e-37
NAFHOKKD_01053 5e-35 T Toxin-antitoxin system, toxin component, MazF family
NAFHOKKD_01054 1.6e-23 S Protein of unknown function (DUF3290)
NAFHOKKD_01055 2.3e-41 ybaN S Protein of unknown function (DUF454)
NAFHOKKD_01056 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NAFHOKKD_01057 7.2e-158 endA V DNA/RNA non-specific endonuclease
NAFHOKKD_01058 6.6e-254 yifK E Amino acid permease
NAFHOKKD_01060 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NAFHOKKD_01061 4.6e-230 N Uncharacterized conserved protein (DUF2075)
NAFHOKKD_01062 9.1e-119 S SNARE associated Golgi protein
NAFHOKKD_01063 0.0 uvrA3 L excinuclease ABC, A subunit
NAFHOKKD_01064 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NAFHOKKD_01065 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NAFHOKKD_01066 4.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NAFHOKKD_01067 1.6e-143 S DUF218 domain
NAFHOKKD_01068 0.0 ubiB S ABC1 family
NAFHOKKD_01069 2.7e-244 yhdP S Transporter associated domain
NAFHOKKD_01070 1.9e-74 copY K Copper transport repressor CopY TcrY
NAFHOKKD_01071 2.8e-37 EGP Major facilitator Superfamily
NAFHOKKD_01072 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NAFHOKKD_01073 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NAFHOKKD_01074 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
NAFHOKKD_01075 6.5e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NAFHOKKD_01076 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
NAFHOKKD_01077 1.1e-239 hemL 5.4.3.8 H Aminotransferase class-III
NAFHOKKD_01078 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
NAFHOKKD_01079 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NAFHOKKD_01080 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NAFHOKKD_01081 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
NAFHOKKD_01082 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NAFHOKKD_01083 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
NAFHOKKD_01084 1.5e-102 cbiQ P Cobalt transport protein
NAFHOKKD_01085 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NAFHOKKD_01086 4.5e-124 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NAFHOKKD_01087 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NAFHOKKD_01088 6.2e-108 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
NAFHOKKD_01089 1.6e-175 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NAFHOKKD_01090 2.8e-97 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
NAFHOKKD_01091 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NAFHOKKD_01092 2.1e-143 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
NAFHOKKD_01093 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NAFHOKKD_01094 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NAFHOKKD_01095 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NAFHOKKD_01096 1.3e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NAFHOKKD_01097 9.3e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
NAFHOKKD_01098 2.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NAFHOKKD_01099 7.3e-205 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
NAFHOKKD_01100 6.1e-170 cobD 4.1.1.81 E Aminotransferase class I and II
NAFHOKKD_01101 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
NAFHOKKD_01102 2.5e-115 XK27_04590 S NADPH-dependent FMN reductase
NAFHOKKD_01103 2.2e-73 fld C Flavodoxin
NAFHOKKD_01104 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
NAFHOKKD_01105 5.9e-68 P Cadmium resistance transporter
NAFHOKKD_01106 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
NAFHOKKD_01107 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
NAFHOKKD_01108 3e-54 pduU E BMC
NAFHOKKD_01109 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NAFHOKKD_01110 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
NAFHOKKD_01111 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
NAFHOKKD_01112 4.5e-77 pduO S Haem-degrading
NAFHOKKD_01113 1e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
NAFHOKKD_01114 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
NAFHOKKD_01115 1.3e-79 S Putative propanediol utilisation
NAFHOKKD_01116 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NAFHOKKD_01117 7.8e-40 pduA_4 CQ BMC
NAFHOKKD_01118 1.8e-56 pduK CQ BMC
NAFHOKKD_01119 2.6e-45 pduH S Dehydratase medium subunit
NAFHOKKD_01120 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
NAFHOKKD_01121 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
NAFHOKKD_01122 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
NAFHOKKD_01123 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
NAFHOKKD_01124 2.7e-134 pduB E BMC
NAFHOKKD_01125 1.6e-37 pduA_4 CQ BMC
NAFHOKKD_01126 2.1e-37 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NAFHOKKD_01127 2.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NAFHOKKD_01128 0.0 copA 3.6.3.54 P P-type ATPase
NAFHOKKD_01129 3.1e-86
NAFHOKKD_01131 1.8e-56
NAFHOKKD_01132 1e-145 yjcE P Sodium proton antiporter
NAFHOKKD_01133 1.5e-78 yjcE P Sodium proton antiporter
NAFHOKKD_01135 3.8e-87
NAFHOKKD_01136 0.0 M domain protein
NAFHOKKD_01137 1.8e-19
NAFHOKKD_01138 5.3e-184 ampC V Beta-lactamase
NAFHOKKD_01139 4.4e-217 arcA 3.5.3.6 E Arginine
NAFHOKKD_01140 2.7e-79 argR K Regulates arginine biosynthesis genes
NAFHOKKD_01141 5.4e-259 E Arginine ornithine antiporter
NAFHOKKD_01142 6.7e-222 arcD U Amino acid permease
NAFHOKKD_01143 3e-10
NAFHOKKD_01144 9.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NAFHOKKD_01145 3.7e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NAFHOKKD_01146 6e-108 tdk 2.7.1.21 F thymidine kinase
NAFHOKKD_01147 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NAFHOKKD_01148 6.6e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NAFHOKKD_01149 1.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NAFHOKKD_01150 8.6e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NAFHOKKD_01151 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NAFHOKKD_01152 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NAFHOKKD_01153 5.8e-192 yibE S overlaps another CDS with the same product name
NAFHOKKD_01154 2.6e-130 yibF S overlaps another CDS with the same product name
NAFHOKKD_01155 5.9e-233 pyrP F Permease
NAFHOKKD_01156 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
NAFHOKKD_01157 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NAFHOKKD_01158 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NAFHOKKD_01159 3.3e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NAFHOKKD_01160 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NAFHOKKD_01161 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NAFHOKKD_01162 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NAFHOKKD_01163 1e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NAFHOKKD_01164 2.8e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NAFHOKKD_01165 5.7e-194 L Transposase
NAFHOKKD_01166 0.0 tetP J elongation factor G
NAFHOKKD_01167 5.1e-81 uspA T universal stress protein
NAFHOKKD_01168 8.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
NAFHOKKD_01169 7.1e-63
NAFHOKKD_01170 4e-14
NAFHOKKD_01171 2.6e-105
NAFHOKKD_01172 1e-135 V ABC transporter
NAFHOKKD_01173 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01174 1e-41 L transposase IS116 IS110 IS902 family protein
NAFHOKKD_01175 4.3e-83 usp6 T universal stress protein
NAFHOKKD_01176 4.4e-46
NAFHOKKD_01177 2.2e-235 rarA L recombination factor protein RarA
NAFHOKKD_01178 2.7e-85 yueI S Protein of unknown function (DUF1694)
NAFHOKKD_01179 4.5e-21
NAFHOKKD_01180 8.1e-75 4.4.1.5 E Glyoxalase
NAFHOKKD_01181 2.5e-138 S Membrane
NAFHOKKD_01182 3.8e-139 S Belongs to the UPF0246 family
NAFHOKKD_01183 2.6e-186 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NAFHOKKD_01184 1.1e-33 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NAFHOKKD_01185 1.5e-32 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NAFHOKKD_01186 2.5e-258 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NAFHOKKD_01187 1.1e-234 pbuG S permease
NAFHOKKD_01188 4.8e-276 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NAFHOKKD_01189 1.1e-157 gadC E amino acid
NAFHOKKD_01190 7e-66 gadC E amino acid
NAFHOKKD_01191 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NAFHOKKD_01192 2.5e-239 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NAFHOKKD_01193 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
NAFHOKKD_01194 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NAFHOKKD_01195 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NAFHOKKD_01196 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
NAFHOKKD_01197 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NAFHOKKD_01198 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NAFHOKKD_01199 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NAFHOKKD_01200 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
NAFHOKKD_01201 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NAFHOKKD_01202 8e-122 radC L DNA repair protein
NAFHOKKD_01203 1.7e-179 mreB D cell shape determining protein MreB
NAFHOKKD_01204 3.5e-152 mreC M Involved in formation and maintenance of cell shape
NAFHOKKD_01205 8.7e-93 mreD M rod shape-determining protein MreD
NAFHOKKD_01206 3.2e-102 glnP P ABC transporter permease
NAFHOKKD_01207 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NAFHOKKD_01208 1.7e-159 aatB ET ABC transporter substrate-binding protein
NAFHOKKD_01209 7.6e-225 ymfF S Peptidase M16 inactive domain protein
NAFHOKKD_01210 2.3e-248 ymfH S Peptidase M16
NAFHOKKD_01211 3.8e-137 ymfM S Helix-turn-helix domain
NAFHOKKD_01212 2.7e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NAFHOKKD_01213 3.6e-227 cinA 3.5.1.42 S Belongs to the CinA family
NAFHOKKD_01214 1.7e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NAFHOKKD_01215 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
NAFHOKKD_01216 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NAFHOKKD_01217 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NAFHOKKD_01218 2.1e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NAFHOKKD_01219 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NAFHOKKD_01220 2.2e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NAFHOKKD_01221 9e-30 yajC U Preprotein translocase
NAFHOKKD_01222 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NAFHOKKD_01223 2.2e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NAFHOKKD_01224 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NAFHOKKD_01225 4.1e-43 yrzL S Belongs to the UPF0297 family
NAFHOKKD_01226 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NAFHOKKD_01227 6.1e-48 yrzB S Belongs to the UPF0473 family
NAFHOKKD_01228 1.6e-86 cvpA S Colicin V production protein
NAFHOKKD_01229 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NAFHOKKD_01230 7.9e-54 trxA O Belongs to the thioredoxin family
NAFHOKKD_01232 2.1e-212 kgtP EGP Sugar (and other) transporter
NAFHOKKD_01233 2e-166 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NAFHOKKD_01236 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01237 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NAFHOKKD_01238 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NAFHOKKD_01239 1.4e-47 gcvH E glycine cleavage
NAFHOKKD_01240 1.1e-220 rodA D Belongs to the SEDS family
NAFHOKKD_01241 1e-31 S Protein of unknown function (DUF2969)
NAFHOKKD_01242 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NAFHOKKD_01243 1.9e-178 mbl D Cell shape determining protein MreB Mrl
NAFHOKKD_01244 3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NAFHOKKD_01245 1.3e-33 ywzB S Protein of unknown function (DUF1146)
NAFHOKKD_01246 2.8e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NAFHOKKD_01248 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01249 3e-27 L PFAM transposase IS200-family protein
NAFHOKKD_01250 2.4e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NAFHOKKD_01251 6.9e-202 XK27_09615 S reductase
NAFHOKKD_01252 2.9e-102 nqr 1.5.1.36 S reductase
NAFHOKKD_01254 2.1e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NAFHOKKD_01255 2.1e-77 K Transcriptional regulator, LacI family
NAFHOKKD_01256 8.1e-42 gntT EG Gluconate
NAFHOKKD_01257 3.2e-173 gntT EG Gluconate
NAFHOKKD_01258 3.3e-294 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NAFHOKKD_01259 2.9e-96 K Acetyltransferase (GNAT) domain
NAFHOKKD_01260 3.9e-237 L Transposase
NAFHOKKD_01261 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
NAFHOKKD_01262 8.1e-79 F NUDIX domain
NAFHOKKD_01263 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NAFHOKKD_01264 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NAFHOKKD_01265 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NAFHOKKD_01266 1.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
NAFHOKKD_01267 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NAFHOKKD_01268 7.1e-161 dprA LU DNA protecting protein DprA
NAFHOKKD_01269 4.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NAFHOKKD_01270 2.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NAFHOKKD_01271 4.4e-35 yozE S Belongs to the UPF0346 family
NAFHOKKD_01272 8.2e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NAFHOKKD_01273 8.3e-168 ypmR E lipolytic protein G-D-S-L family
NAFHOKKD_01274 4.9e-151 DegV S EDD domain protein, DegV family
NAFHOKKD_01275 1.9e-110 hlyIII S protein, hemolysin III
NAFHOKKD_01276 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NAFHOKKD_01277 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NAFHOKKD_01278 0.0 yfmR S ABC transporter, ATP-binding protein
NAFHOKKD_01279 8.2e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NAFHOKKD_01280 1.4e-234 S Tetratricopeptide repeat protein
NAFHOKKD_01281 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NAFHOKKD_01282 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NAFHOKKD_01283 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NAFHOKKD_01284 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NAFHOKKD_01285 2.5e-13 M Lysin motif
NAFHOKKD_01286 6.4e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NAFHOKKD_01287 8.8e-195 ypbB 5.1.3.1 S Helix-turn-helix domain
NAFHOKKD_01288 3e-99 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NAFHOKKD_01289 1e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NAFHOKKD_01290 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NAFHOKKD_01291 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NAFHOKKD_01292 1.1e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NAFHOKKD_01293 2.9e-162 xerD D recombinase XerD
NAFHOKKD_01294 3.3e-166 cvfB S S1 domain
NAFHOKKD_01295 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NAFHOKKD_01296 0.0 dnaE 2.7.7.7 L DNA polymerase
NAFHOKKD_01297 2e-29 S Protein of unknown function (DUF2929)
NAFHOKKD_01298 3e-170 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NAFHOKKD_01299 3.2e-54 hol S COG5546 Small integral membrane protein
NAFHOKKD_01300 5.2e-32
NAFHOKKD_01304 9.1e-113
NAFHOKKD_01305 1.1e-31 S GDSL-like Lipase/Acylhydrolase
NAFHOKKD_01309 3.9e-237 L Transposase
NAFHOKKD_01310 2.2e-72
NAFHOKKD_01311 3.1e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NAFHOKKD_01312 2.2e-271 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NAFHOKKD_01313 8.6e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
NAFHOKKD_01314 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NAFHOKKD_01315 3.7e-265 G Major Facilitator
NAFHOKKD_01316 3.9e-237 L Transposase
NAFHOKKD_01317 5.9e-73 S ECF transporter, substrate-specific component
NAFHOKKD_01318 9.8e-51 S Domain of unknown function (DUF4430)
NAFHOKKD_01319 8.1e-18 cnrT EG PFAM EamA-like transporter family
NAFHOKKD_01320 2.5e-19 cnrT EG PFAM EamA-like transporter family
NAFHOKKD_01321 6.1e-52 L Transposase
NAFHOKKD_01322 3.9e-237 L Transposase
NAFHOKKD_01323 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NAFHOKKD_01324 6e-263 argH 4.3.2.1 E argininosuccinate lyase
NAFHOKKD_01325 3.8e-83 bioY S BioY family
NAFHOKKD_01326 2.2e-171 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NAFHOKKD_01327 7.9e-180 phoH T phosphate starvation-inducible protein PhoH
NAFHOKKD_01328 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NAFHOKKD_01329 4.7e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NAFHOKKD_01330 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NAFHOKKD_01331 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
NAFHOKKD_01332 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NAFHOKKD_01333 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NAFHOKKD_01334 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NAFHOKKD_01335 7.7e-208 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NAFHOKKD_01336 2.4e-220 patA 2.6.1.1 E Aminotransferase
NAFHOKKD_01337 1.4e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
NAFHOKKD_01338 7.9e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NAFHOKKD_01339 2.8e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NAFHOKKD_01340 6.2e-93 L Belongs to the 'phage' integrase family
NAFHOKKD_01344 4e-75 E IrrE N-terminal-like domain
NAFHOKKD_01345 1.8e-48 K addiction module antidote protein HigA
NAFHOKKD_01348 1.3e-20
NAFHOKKD_01349 1.4e-106 S Protein of unknown function (DUF3102)
NAFHOKKD_01351 4e-08
NAFHOKKD_01354 3.8e-07
NAFHOKKD_01355 3.9e-237 L Transposase
NAFHOKKD_01356 2.7e-67 yqkB S Belongs to the HesB IscA family
NAFHOKKD_01357 3.9e-237 L Transposase
NAFHOKKD_01358 3.1e-104 yxjI
NAFHOKKD_01359 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NAFHOKKD_01360 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NAFHOKKD_01361 6.4e-79 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NAFHOKKD_01362 2.8e-85 K Acetyltransferase (GNAT) domain
NAFHOKKD_01363 1.7e-75 S PAS domain
NAFHOKKD_01364 6e-102 dnaQ 2.7.7.7 L DNA polymerase III
NAFHOKKD_01365 3e-167 murB 1.3.1.98 M Cell wall formation
NAFHOKKD_01366 9.4e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NAFHOKKD_01367 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NAFHOKKD_01368 4.8e-249 fucP G Major Facilitator Superfamily
NAFHOKKD_01369 1.4e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NAFHOKKD_01370 9e-127 ybbR S YbbR-like protein
NAFHOKKD_01371 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NAFHOKKD_01372 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NAFHOKKD_01373 5.6e-52
NAFHOKKD_01374 0.0 oatA I Acyltransferase
NAFHOKKD_01375 1.8e-78 K Transcriptional regulator
NAFHOKKD_01376 3.2e-147 XK27_02985 S Cof-like hydrolase
NAFHOKKD_01377 1.3e-76 lytE M Lysin motif
NAFHOKKD_01379 1.6e-134 K response regulator
NAFHOKKD_01380 2.6e-272 yclK 2.7.13.3 T Histidine kinase
NAFHOKKD_01381 4.1e-153 glcU U sugar transport
NAFHOKKD_01382 1.9e-99 lacA 2.3.1.79 S Transferase hexapeptide repeat
NAFHOKKD_01383 2.9e-262 pgi 5.3.1.9 G Belongs to the GPI family
NAFHOKKD_01384 7.8e-26
NAFHOKKD_01385 3.9e-237 L Transposase
NAFHOKKD_01386 1.1e-13 steT_1 E amino acid
NAFHOKKD_01388 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NAFHOKKD_01389 1.1e-83
NAFHOKKD_01390 5.3e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NAFHOKKD_01391 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NAFHOKKD_01392 5.3e-264 nox C NADH oxidase
NAFHOKKD_01393 3e-87 hmpT S ECF-type riboflavin transporter, S component
NAFHOKKD_01394 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NAFHOKKD_01395 2.9e-167 yvgN C Aldo keto reductase
NAFHOKKD_01396 3.5e-137 puuD S peptidase C26
NAFHOKKD_01397 4.7e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NAFHOKKD_01398 4.7e-216 yfeO P Voltage gated chloride channel
NAFHOKKD_01399 3.1e-226 sptS 2.7.13.3 T Histidine kinase
NAFHOKKD_01400 1.3e-117 K response regulator
NAFHOKKD_01401 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
NAFHOKKD_01402 8.6e-67
NAFHOKKD_01403 1.9e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NAFHOKKD_01404 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NAFHOKKD_01405 1.1e-256 malT G Major Facilitator
NAFHOKKD_01406 3.7e-213 phbA 2.3.1.9 I Belongs to the thiolase family
NAFHOKKD_01407 1.5e-172 malR K Transcriptional regulator, LacI family
NAFHOKKD_01408 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NAFHOKKD_01409 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NAFHOKKD_01410 2.7e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NAFHOKKD_01411 1.2e-103 wecD3 K PFAM GCN5-related N-acetyltransferase
NAFHOKKD_01413 0.0 clpL O associated with various cellular activities
NAFHOKKD_01414 7.8e-32
NAFHOKKD_01415 9.8e-214 patA 2.6.1.1 E Aminotransferase
NAFHOKKD_01416 8.3e-174 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NAFHOKKD_01417 1.4e-72 osmC O OsmC-like protein
NAFHOKKD_01418 3.9e-237 L Transposase
NAFHOKKD_01420 1.1e-13 K Transcriptional
NAFHOKKD_01421 6e-48 L Integrase
NAFHOKKD_01422 6.3e-193 V Beta-lactamase
NAFHOKKD_01423 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NAFHOKKD_01424 1.8e-104 yhiD S MgtC family
NAFHOKKD_01425 7.4e-28 S GyrI-like small molecule binding domain
NAFHOKKD_01426 1.8e-53 S GyrI-like small molecule binding domain
NAFHOKKD_01428 8e-109 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NAFHOKKD_01429 3.2e-50 azlD E Branched-chain amino acid transport
NAFHOKKD_01430 4.5e-118 azlC E azaleucine resistance protein AzlC
NAFHOKKD_01431 1.1e-259 K Aminotransferase class I and II
NAFHOKKD_01432 4.5e-219 S amidohydrolase
NAFHOKKD_01433 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_01434 6.5e-26 L Transposase
NAFHOKKD_01435 2.8e-16 L Transposase
NAFHOKKD_01436 1.4e-156 L Transposase
NAFHOKKD_01437 2.2e-78 S Domain of unknown function (DUF4767)
NAFHOKKD_01438 4.3e-13
NAFHOKKD_01439 7.4e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
NAFHOKKD_01440 3.3e-94 ltrA S Bacterial low temperature requirement A protein (LtrA)
NAFHOKKD_01441 1.4e-56 wecD3 K PFAM GCN5-related N-acetyltransferase
NAFHOKKD_01442 3.1e-28 wecD3 K PFAM GCN5-related N-acetyltransferase
NAFHOKKD_01443 1.7e-85 ywlG S Belongs to the UPF0340 family
NAFHOKKD_01444 1e-159 spoU 2.1.1.185 J Methyltransferase
NAFHOKKD_01445 1.3e-224 oxlT P Major Facilitator Superfamily
NAFHOKKD_01446 7.8e-22 L Phage integrase, N-terminal SAM-like domain
NAFHOKKD_01447 1.6e-260 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NAFHOKKD_01448 5.9e-264 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NAFHOKKD_01450 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NAFHOKKD_01451 5.7e-17 asp3 S Accessory Sec secretory system ASP3
NAFHOKKD_01452 2.6e-257 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
NAFHOKKD_01453 5.9e-259 asp1 S Accessory Sec system protein Asp1
NAFHOKKD_01454 4.7e-190 secY2 U SecY translocase
NAFHOKKD_01455 3.4e-22 arbx M family 8
NAFHOKKD_01457 2.2e-65 L transposase and inactivated derivatives, IS30 family
NAFHOKKD_01459 3.5e-13 XK27_01125 L PFAM IS66 Orf2 family protein
NAFHOKKD_01460 1.4e-87 L hmm pf00665
NAFHOKKD_01461 1.4e-54 L Helix-turn-helix domain
NAFHOKKD_01462 3.7e-176 L Transposase IS66 family
NAFHOKKD_01465 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_01466 6.3e-14
NAFHOKKD_01467 2.5e-16
NAFHOKKD_01470 9.6e-09 XK27_00515 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NAFHOKKD_01471 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_01472 1.9e-66
NAFHOKKD_01473 7.9e-40
NAFHOKKD_01474 2.4e-77 NU general secretion pathway protein
NAFHOKKD_01475 7.1e-47 comGC U competence protein ComGC
NAFHOKKD_01476 4.4e-178 comGB NU type II secretion system
NAFHOKKD_01477 1.1e-178 comGA NU Type II IV secretion system protein
NAFHOKKD_01478 3.5e-132 yebC K Transcriptional regulatory protein
NAFHOKKD_01479 1.8e-132
NAFHOKKD_01480 4.2e-181 ccpA K catabolite control protein A
NAFHOKKD_01481 1e-209 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NAFHOKKD_01482 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_01483 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NAFHOKKD_01485 9.6e-200 xerS L Belongs to the 'phage' integrase family
NAFHOKKD_01486 1.8e-205 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NAFHOKKD_01487 2.2e-18 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NAFHOKKD_01488 3e-156 rssA S Phospholipase, patatin family
NAFHOKKD_01489 9.4e-118 L Integrase
NAFHOKKD_01490 1.4e-51 L PFAM Integrase catalytic region
NAFHOKKD_01491 6.9e-34
NAFHOKKD_01492 5.8e-247 pgaC GT2 M Glycosyl transferase
NAFHOKKD_01493 2.7e-138 T EAL domain
NAFHOKKD_01494 6.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
NAFHOKKD_01495 1.9e-59 yneR
NAFHOKKD_01496 1.6e-101 qorB 1.6.5.2 GM NmrA-like family
NAFHOKKD_01497 3.5e-160 akr5f 1.1.1.346 S reductase
NAFHOKKD_01498 1.7e-146 K Transcriptional regulator
NAFHOKKD_01499 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
NAFHOKKD_01500 2.4e-160 ypuA S Protein of unknown function (DUF1002)
NAFHOKKD_01501 6.6e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NAFHOKKD_01502 4e-92 tesE Q hydratase
NAFHOKKD_01503 4e-50 tesE Q hydratase
NAFHOKKD_01504 9e-101 S Alpha beta hydrolase
NAFHOKKD_01506 3.8e-68 lacA S transferase hexapeptide repeat
NAFHOKKD_01507 4.7e-17 P nitric oxide dioxygenase activity
NAFHOKKD_01508 5.5e-90 S Peptidase propeptide and YPEB domain
NAFHOKKD_01509 2e-75 T GHKL domain
NAFHOKKD_01510 1.1e-107 T GHKL domain
NAFHOKKD_01511 5.6e-110 T Transcriptional regulatory protein, C terminal
NAFHOKKD_01512 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01513 2.8e-95 cadD P Cadmium resistance transporter
NAFHOKKD_01514 3.2e-56 cadX K Bacterial regulatory protein, arsR family
NAFHOKKD_01515 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NAFHOKKD_01516 8.6e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
NAFHOKKD_01517 1.8e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
NAFHOKKD_01518 1.8e-256 gor 1.8.1.7 C Glutathione reductase
NAFHOKKD_01519 5.3e-57 ywfI S Chlorite dismutase
NAFHOKKD_01520 3.2e-45 ywfI S Chlorite dismutase
NAFHOKKD_01521 1.1e-245 emrY EGP Major facilitator Superfamily
NAFHOKKD_01522 1.8e-175 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NAFHOKKD_01523 9.5e-72 macB_3 V FtsX-like permease family
NAFHOKKD_01524 6.2e-90 S PAS domain
NAFHOKKD_01527 6.4e-18 K Helix-turn-helix domain
NAFHOKKD_01528 1.7e-271 S ABC transporter, ATP-binding protein
NAFHOKKD_01529 2.1e-140 S Putative ABC-transporter type IV
NAFHOKKD_01530 2.9e-105 NU mannosyl-glycoprotein
NAFHOKKD_01531 5.4e-248 brnQ U Component of the transport system for branched-chain amino acids
NAFHOKKD_01532 1.8e-226 S Uncharacterized protein conserved in bacteria (DUF2325)
NAFHOKKD_01533 8.9e-206 nrnB S DHHA1 domain
NAFHOKKD_01534 2.8e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NAFHOKKD_01535 1.9e-55 trxA O Belongs to the thioredoxin family
NAFHOKKD_01536 6.6e-131 terC P membrane
NAFHOKKD_01537 3.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NAFHOKKD_01538 2.8e-168 corA P CorA-like Mg2+ transporter protein
NAFHOKKD_01539 1.8e-278 pipD E Dipeptidase
NAFHOKKD_01540 4.7e-241 pbuX F xanthine permease
NAFHOKKD_01541 1e-246 nhaC C Na H antiporter NhaC
NAFHOKKD_01542 2.3e-102 S C4-dicarboxylate anaerobic carrier
NAFHOKKD_01543 1.8e-162 S C4-dicarboxylate anaerobic carrier
NAFHOKKD_01544 6.4e-46 IQ Dehydrogenase reductase
NAFHOKKD_01545 2.8e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NAFHOKKD_01546 4.1e-51 epsB M biosynthesis protein
NAFHOKKD_01547 2.6e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NAFHOKKD_01548 2.3e-08 K Transcriptional regulator, HxlR family
NAFHOKKD_01549 4.7e-35
NAFHOKKD_01550 2.9e-82
NAFHOKKD_01551 3.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NAFHOKKD_01552 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NAFHOKKD_01553 0.0 yjbQ P TrkA C-terminal domain protein
NAFHOKKD_01554 3.9e-270 pipD E Dipeptidase
NAFHOKKD_01555 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NAFHOKKD_01556 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
NAFHOKKD_01557 6.3e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NAFHOKKD_01558 3.2e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NAFHOKKD_01561 7.2e-185 L transposase, IS605 OrfB family
NAFHOKKD_01562 3.2e-51 L Transposase IS200 like
NAFHOKKD_01563 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NAFHOKKD_01564 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
NAFHOKKD_01565 3.1e-223 mdtG EGP Major facilitator Superfamily
NAFHOKKD_01566 5.7e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NAFHOKKD_01567 4.7e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
NAFHOKKD_01568 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NAFHOKKD_01569 3.9e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NAFHOKKD_01570 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NAFHOKKD_01571 0.0 lacS G Transporter
NAFHOKKD_01572 1.8e-184 lacR K Transcriptional regulator
NAFHOKKD_01573 2.3e-13
NAFHOKKD_01574 2e-36
NAFHOKKD_01575 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
NAFHOKKD_01576 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
NAFHOKKD_01577 8.5e-34
NAFHOKKD_01578 2.8e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NAFHOKKD_01579 5.9e-66 L Helix-turn-helix domain
NAFHOKKD_01580 9.4e-126 L hmm pf00665
NAFHOKKD_01581 1.3e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NAFHOKKD_01583 2.8e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NAFHOKKD_01584 2e-236 mepA V MATE efflux family protein
NAFHOKKD_01585 7.6e-55 K Transcriptional regulator, ArsR family
NAFHOKKD_01586 4.8e-94 P Cadmium resistance transporter
NAFHOKKD_01587 1.8e-136 XK27_08845 S ABC transporter, ATP-binding protein
NAFHOKKD_01588 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NAFHOKKD_01589 2.2e-182 ABC-SBP S ABC transporter
NAFHOKKD_01590 2.3e-73 M PFAM NLP P60 protein
NAFHOKKD_01592 1.6e-39 S Protein of unknown function (DUF3278)
NAFHOKKD_01593 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01594 2e-211 EGP Major facilitator Superfamily
NAFHOKKD_01595 1.5e-256 G PTS system Galactitol-specific IIC component
NAFHOKKD_01596 9.8e-23 1.6.5.5 C Zinc-binding dehydrogenase
NAFHOKKD_01597 5e-85 1.6.5.5 C Zinc-binding dehydrogenase
NAFHOKKD_01598 1.3e-159
NAFHOKKD_01599 1e-72 K Transcriptional regulator
NAFHOKKD_01600 7.6e-188 D Alpha beta
NAFHOKKD_01601 6.4e-52 ypaA S Protein of unknown function (DUF1304)
NAFHOKKD_01602 0.0 yjcE P Sodium proton antiporter
NAFHOKKD_01603 1.6e-52 yvlA
NAFHOKKD_01604 9.5e-110 P Cobalt transport protein
NAFHOKKD_01605 2.1e-247 cbiO1 S ABC transporter, ATP-binding protein
NAFHOKKD_01606 1.3e-96 S ABC-type cobalt transport system, permease component
NAFHOKKD_01607 3.3e-133 S membrane transporter protein
NAFHOKKD_01608 4e-113 IQ KR domain
NAFHOKKD_01609 2e-09 IQ KR domain
NAFHOKKD_01610 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01611 4.5e-58 S Phage portal protein, SPP1 Gp6-like
NAFHOKKD_01612 8.1e-174 ps334 S Terminase-like family
NAFHOKKD_01613 3e-58 ps333 L Terminase small subunit
NAFHOKKD_01614 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01615 1.4e-27 sspC 2.7.7.7 DM Glucan-binding protein C
NAFHOKKD_01616 1.1e-127 L Belongs to the 'phage' integrase family
NAFHOKKD_01622 4.1e-79 endA F DNA RNA non-specific endonuclease
NAFHOKKD_01624 6.6e-188 S regulation of response to stimulus
NAFHOKKD_01626 8.9e-59 M CHAP domain
NAFHOKKD_01630 7.5e-56 L Lactococcus lactis RepB C-terminus
NAFHOKKD_01631 6.7e-36
NAFHOKKD_01635 8.2e-160 U TraM recognition site of TraD and TraG
NAFHOKKD_01639 8.7e-93
NAFHOKKD_01641 2.5e-31 soj D AAA domain
NAFHOKKD_01643 9.2e-21
NAFHOKKD_01645 1.4e-12 ispH 1.17.7.4 J negative regulation of cytoplasmic translation
NAFHOKKD_01646 7.6e-77
NAFHOKKD_01650 2.7e-08 nucH 3.1.31.1 L Staphylococcal nuclease homologues
NAFHOKKD_01652 3.7e-69 3.4.22.70 M sortase family
NAFHOKKD_01653 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01654 7e-19 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
NAFHOKKD_01656 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NAFHOKKD_01657 3.9e-237 L Transposase
NAFHOKKD_01658 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NAFHOKKD_01659 2.4e-53 ysxB J Cysteine protease Prp
NAFHOKKD_01660 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NAFHOKKD_01661 8.9e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NAFHOKKD_01662 1.6e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NAFHOKKD_01663 9.5e-113 J 2'-5' RNA ligase superfamily
NAFHOKKD_01664 2.2e-70 yqhY S Asp23 family, cell envelope-related function
NAFHOKKD_01665 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NAFHOKKD_01666 8.8e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NAFHOKKD_01667 6.5e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NAFHOKKD_01668 6.2e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NAFHOKKD_01669 7.1e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NAFHOKKD_01670 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NAFHOKKD_01671 1.6e-76 argR K Regulates arginine biosynthesis genes
NAFHOKKD_01672 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
NAFHOKKD_01673 4.2e-53
NAFHOKKD_01674 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NAFHOKKD_01675 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NAFHOKKD_01676 1.3e-208 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NAFHOKKD_01677 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NAFHOKKD_01678 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NAFHOKKD_01679 2.4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NAFHOKKD_01680 6.1e-129 stp 3.1.3.16 T phosphatase
NAFHOKKD_01681 0.0 KLT serine threonine protein kinase
NAFHOKKD_01682 1.2e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NAFHOKKD_01683 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NAFHOKKD_01684 3.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
NAFHOKKD_01685 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NAFHOKKD_01686 4.7e-58 asp S Asp23 family, cell envelope-related function
NAFHOKKD_01687 0.0 yloV S DAK2 domain fusion protein YloV
NAFHOKKD_01688 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NAFHOKKD_01689 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NAFHOKKD_01690 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NAFHOKKD_01691 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NAFHOKKD_01692 0.0 smc D Required for chromosome condensation and partitioning
NAFHOKKD_01693 2.4e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NAFHOKKD_01694 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NAFHOKKD_01695 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NAFHOKKD_01696 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NAFHOKKD_01697 7e-40 ylqC S Belongs to the UPF0109 family
NAFHOKKD_01698 7.6e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NAFHOKKD_01699 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NAFHOKKD_01700 1.2e-258 yfnA E amino acid
NAFHOKKD_01701 3.6e-152 D CobQ CobB MinD ParA nucleotide binding domain protein
NAFHOKKD_01702 4.5e-40
NAFHOKKD_01703 2e-77 L An automated process has identified a potential problem with this gene model
NAFHOKKD_01704 2.8e-87 D CobQ CobB MinD ParA nucleotide binding domain protein
NAFHOKKD_01706 2.2e-41 hxlR K Transcriptional regulator, HxlR family
NAFHOKKD_01707 2.9e-166 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NAFHOKKD_01709 3.1e-104 L Integrase
NAFHOKKD_01710 6.4e-33 S RelB antitoxin
NAFHOKKD_01711 1e-44
NAFHOKKD_01713 2e-181
NAFHOKKD_01714 3.1e-24 L Transposase DDE domain group 1
NAFHOKKD_01715 2.6e-43 K Transcriptional regulator
NAFHOKKD_01716 3.5e-137 M Exporter of polyketide antibiotics
NAFHOKKD_01717 3.7e-120 ecsA_1 S ABC transporter
NAFHOKKD_01718 1e-21 L Transposase DDE domain group 1
NAFHOKKD_01719 8.7e-16
NAFHOKKD_01720 8.8e-199 ykiI
NAFHOKKD_01721 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAFHOKKD_01722 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAFHOKKD_01723 1e-110 K Bacterial regulatory proteins, tetR family
NAFHOKKD_01724 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NAFHOKKD_01725 4.4e-77 ctsR K Belongs to the CtsR family
NAFHOKKD_01726 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
NAFHOKKD_01727 1.4e-76 S Hydrolases of the alpha beta superfamily
NAFHOKKD_01728 7.7e-42 L Integrase core domain
NAFHOKKD_01729 5.1e-139 L Bacterial dnaA protein
NAFHOKKD_01730 7.4e-145 L Transposase
NAFHOKKD_01732 1.3e-45 M NlpC P60 family protein
NAFHOKKD_01733 0.0 S Peptidase family M23
NAFHOKKD_01734 2e-152 S Phage tail protein
NAFHOKKD_01735 1.1e-260 D NLP P60 protein
NAFHOKKD_01736 2.7e-128 D NLP P60 protein
NAFHOKKD_01737 6.9e-14
NAFHOKKD_01738 3.6e-34 S Phage tail assembly chaperone protein, TAC
NAFHOKKD_01739 6.5e-77
NAFHOKKD_01740 5.2e-34
NAFHOKKD_01741 2.5e-49
NAFHOKKD_01742 1.6e-42
NAFHOKKD_01743 1.3e-41 S Phage gp6-like head-tail connector protein
NAFHOKKD_01744 2.5e-88 gpG
NAFHOKKD_01745 1.7e-07 S Domain of unknown function (DUF4355)
NAFHOKKD_01746 4.9e-96 S Phage Mu protein F like protein
NAFHOKKD_01747 1.5e-107 S Phage portal protein, SPP1 Gp6-like
NAFHOKKD_01748 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_01749 9.3e-53 L MULE transposase domain
NAFHOKKD_01750 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NAFHOKKD_01751 1.4e-51 L PFAM Integrase catalytic region
NAFHOKKD_01752 2.1e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NAFHOKKD_01753 1.9e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NAFHOKKD_01754 4e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NAFHOKKD_01755 2e-241 L PFAM Integrase catalytic region
NAFHOKKD_01756 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
NAFHOKKD_01757 7.5e-58 ytzB S Small secreted protein
NAFHOKKD_01758 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NAFHOKKD_01759 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NAFHOKKD_01760 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NAFHOKKD_01761 1.9e-119 ybhL S Belongs to the BI1 family
NAFHOKKD_01762 1.3e-114 yoaK S Protein of unknown function (DUF1275)
NAFHOKKD_01763 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NAFHOKKD_01764 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NAFHOKKD_01765 1.7e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NAFHOKKD_01766 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NAFHOKKD_01767 5.9e-223 dnaB L replication initiation and membrane attachment
NAFHOKKD_01768 1.9e-172 dnaI L Primosomal protein DnaI
NAFHOKKD_01769 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NAFHOKKD_01770 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NAFHOKKD_01771 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NAFHOKKD_01772 2.4e-95 yqeG S HAD phosphatase, family IIIA
NAFHOKKD_01773 4.8e-218 yqeH S Ribosome biogenesis GTPase YqeH
NAFHOKKD_01774 1.9e-47 yhbY J RNA-binding protein
NAFHOKKD_01775 4.5e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NAFHOKKD_01776 6.2e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NAFHOKKD_01777 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NAFHOKKD_01778 8.7e-136 yqeM Q Methyltransferase
NAFHOKKD_01779 5.3e-209 ylbM S Belongs to the UPF0348 family
NAFHOKKD_01780 4.9e-99 yceD S Uncharacterized ACR, COG1399
NAFHOKKD_01781 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NAFHOKKD_01782 1.5e-121 K response regulator
NAFHOKKD_01783 9.8e-280 arlS 2.7.13.3 T Histidine kinase
NAFHOKKD_01784 2e-241 L PFAM Integrase catalytic region
NAFHOKKD_01785 1.5e-29
NAFHOKKD_01786 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NAFHOKKD_01788 1.3e-86 yxiO S Vacuole effluxer Atg22 like
NAFHOKKD_01789 2e-93 yxiO S Vacuole effluxer Atg22 like
NAFHOKKD_01790 5.5e-214 npp S type I phosphodiesterase nucleotide pyrophosphatase
NAFHOKKD_01791 7.9e-32 npp S type I phosphodiesterase nucleotide pyrophosphatase
NAFHOKKD_01792 6.6e-238 E amino acid
NAFHOKKD_01793 7.4e-68 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NAFHOKKD_01794 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NAFHOKKD_01796 1.5e-219 yxjG_1 E methionine synthase, vitamin-B12 independent
NAFHOKKD_01797 1.1e-28 S Cytochrome B5
NAFHOKKD_01798 9.6e-74 elaA S Gnat family
NAFHOKKD_01799 1.2e-120 GM NmrA-like family
NAFHOKKD_01800 1.8e-50 hxlR K Transcriptional regulator, HxlR family
NAFHOKKD_01801 4.1e-107 XK27_02070 S Nitroreductase family
NAFHOKKD_01802 4.4e-82 K Transcriptional regulator, HxlR family
NAFHOKKD_01803 2.1e-233
NAFHOKKD_01804 2.2e-210 EGP Major facilitator Superfamily
NAFHOKKD_01805 3e-256 pepC 3.4.22.40 E aminopeptidase
NAFHOKKD_01806 6.4e-111 ylbE GM NAD dependent epimerase dehydratase family protein
NAFHOKKD_01807 0.0 pepN 3.4.11.2 E aminopeptidase
NAFHOKKD_01808 1.6e-47 K Transcriptional regulator
NAFHOKKD_01809 3.8e-41 folT S ECF transporter, substrate-specific component
NAFHOKKD_01810 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
NAFHOKKD_01811 1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NAFHOKKD_01812 2.8e-120 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NAFHOKKD_01813 3.2e-193 2.7.7.65 T GGDEF domain
NAFHOKKD_01815 5.8e-61 XK27_01125 L PFAM IS66 Orf2 family protein
NAFHOKKD_01816 9.2e-281 L Transposase IS66 family
NAFHOKKD_01818 5.8e-61 XK27_01125 L PFAM IS66 Orf2 family protein
NAFHOKKD_01819 2.1e-60 L Transposase IS66 family
NAFHOKKD_01820 1.6e-94 2.3.1.128 K Acetyltransferase (GNAT) domain
NAFHOKKD_01821 3.4e-148 lmrB EGP Major facilitator Superfamily
NAFHOKKD_01822 1.6e-62 lmrB EGP Major facilitator Superfamily
NAFHOKKD_01823 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NAFHOKKD_01824 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NAFHOKKD_01825 2.8e-157 sufD O Uncharacterized protein family (UPF0051)
NAFHOKKD_01826 2e-42 lytE M LysM domain protein
NAFHOKKD_01827 0.0 oppD EP Psort location Cytoplasmic, score
NAFHOKKD_01828 7.3e-84 lytE M LysM domain protein
NAFHOKKD_01829 5.7e-85 xth 3.1.11.2 L exodeoxyribonuclease III
NAFHOKKD_01830 1.1e-231 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NAFHOKKD_01831 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
NAFHOKKD_01832 5.3e-153 yeaE S Aldo keto
NAFHOKKD_01833 7.7e-76 hsp O Belongs to the small heat shock protein (HSP20) family
NAFHOKKD_01834 8.7e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NAFHOKKD_01835 7.7e-79 S Psort location Cytoplasmic, score
NAFHOKKD_01836 6.5e-85 S Short repeat of unknown function (DUF308)
NAFHOKKD_01837 5.8e-61 XK27_01125 L PFAM IS66 Orf2 family protein
NAFHOKKD_01848 6e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
NAFHOKKD_01849 3.2e-20
NAFHOKKD_01850 6.6e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NAFHOKKD_01851 2.3e-117 L Transposase, IS116 IS110 IS902 family
NAFHOKKD_01852 1.1e-150 3.2.1.96, 3.5.1.28 GH73 M repeat protein
NAFHOKKD_01853 4.3e-117 M repeat protein
NAFHOKKD_01854 1.3e-25
NAFHOKKD_01855 3.7e-134 M Glycosyltransferase like family 2
NAFHOKKD_01856 1.1e-108 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NAFHOKKD_01857 3e-83 S Psort location CytoplasmicMembrane, score
NAFHOKKD_01858 2.7e-38 M Peptidase_C39 like family
NAFHOKKD_01859 1.1e-41 S Acyltransferase family
NAFHOKKD_01860 5.6e-46 S dextransucrase activity
NAFHOKKD_01861 2e-163 yueF S AI-2E family transporter
NAFHOKKD_01862 4.3e-227 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NAFHOKKD_01863 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NAFHOKKD_01864 1.2e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NAFHOKKD_01865 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NAFHOKKD_01866 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NAFHOKKD_01867 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NAFHOKKD_01868 1.8e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NAFHOKKD_01869 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NAFHOKKD_01870 3.1e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NAFHOKKD_01871 1.1e-173 K AI-2E family transporter
NAFHOKKD_01872 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NAFHOKKD_01873 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NAFHOKKD_01874 2.5e-127 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NAFHOKKD_01875 2.7e-24 K helix_turn_helix, arabinose operon control protein
NAFHOKKD_01876 1.3e-186 thrC 4.2.3.1 E Threonine synthase
NAFHOKKD_01877 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NAFHOKKD_01878 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NAFHOKKD_01879 4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NAFHOKKD_01880 5.6e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NAFHOKKD_01881 1.5e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NAFHOKKD_01882 3.7e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NAFHOKKD_01883 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NAFHOKKD_01884 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NAFHOKKD_01885 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NAFHOKKD_01886 4.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NAFHOKKD_01887 5.2e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NAFHOKKD_01888 1.8e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NAFHOKKD_01889 1.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NAFHOKKD_01890 1.6e-243 purD 6.3.4.13 F Belongs to the GARS family
NAFHOKKD_01891 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NAFHOKKD_01892 1.8e-166
NAFHOKKD_01893 5.4e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NAFHOKKD_01894 9.4e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
NAFHOKKD_01895 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NAFHOKKD_01896 1.6e-111 S Calcineurin-like phosphoesterase
NAFHOKKD_01897 6.6e-93 yutD S Protein of unknown function (DUF1027)
NAFHOKKD_01898 2.7e-132 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NAFHOKKD_01899 1.5e-102 S Protein of unknown function (DUF1461)
NAFHOKKD_01900 1.6e-109 dedA S SNARE-like domain protein
NAFHOKKD_01901 5.1e-07 IQ Enoyl-(Acyl carrier protein) reductase
NAFHOKKD_01902 4.6e-36 K Bacterial transcriptional regulator
NAFHOKKD_01903 1e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
NAFHOKKD_01904 1.2e-39
NAFHOKKD_01905 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NAFHOKKD_01906 8.4e-207 gldA 1.1.1.6 C dehydrogenase
NAFHOKKD_01907 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NAFHOKKD_01908 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NAFHOKKD_01910 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NAFHOKKD_01911 0.0 uup S ABC transporter, ATP-binding protein
NAFHOKKD_01912 4.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NAFHOKKD_01913 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
NAFHOKKD_01914 4.3e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NAFHOKKD_01915 4.9e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NAFHOKKD_01916 9e-218 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NAFHOKKD_01917 3.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NAFHOKKD_01918 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NAFHOKKD_01919 2.3e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NAFHOKKD_01920 2.8e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NAFHOKKD_01921 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NAFHOKKD_01922 5.4e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NAFHOKKD_01923 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NAFHOKKD_01924 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NAFHOKKD_01925 4.2e-133 fat 3.1.2.21 I Acyl-ACP thioesterase
NAFHOKKD_01926 7.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NAFHOKKD_01927 3.1e-43 yabA L Involved in initiation control of chromosome replication
NAFHOKKD_01928 1.4e-181 holB 2.7.7.7 L DNA polymerase III
NAFHOKKD_01929 2.9e-51 yaaQ S Cyclic-di-AMP receptor
NAFHOKKD_01930 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NAFHOKKD_01931 2.8e-38 S Protein of unknown function (DUF2508)
NAFHOKKD_01932 5.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NAFHOKKD_01933 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NAFHOKKD_01934 1.9e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NAFHOKKD_01935 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NAFHOKKD_01936 3.4e-35 nrdH O Glutaredoxin
NAFHOKKD_01937 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NAFHOKKD_01938 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NAFHOKKD_01939 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NAFHOKKD_01940 1.6e-132 S Putative adhesin
NAFHOKKD_01941 3.2e-83 XK27_06920 S Protein of unknown function (DUF1700)
NAFHOKKD_01942 1.5e-49 K transcriptional regulator PadR family
NAFHOKKD_01943 5.1e-139 L Bacterial dnaA protein
NAFHOKKD_01944 7.7e-42 L Integrase core domain
NAFHOKKD_01945 2.4e-22
NAFHOKKD_01946 2.2e-44
NAFHOKKD_01947 1.6e-41 yhaI S Protein of unknown function (DUF805)
NAFHOKKD_01948 5e-51 L Uncharacterized conserved protein (DUF2075)
NAFHOKKD_01949 5.4e-48 3.2.1.17 LO Uncharacterized conserved protein (DUF2075)
NAFHOKKD_01950 0.0 L PLD-like domain
NAFHOKKD_01952 9.9e-177 rihA F Inosine-uridine preferring nucleoside hydrolase
NAFHOKKD_01953 7.3e-103 T Ion transport 2 domain protein
NAFHOKKD_01954 0.0 S Bacterial membrane protein YfhO
NAFHOKKD_01955 3.4e-206 G Transporter, major facilitator family protein
NAFHOKKD_01956 3.5e-108 yvrI K sigma factor activity
NAFHOKKD_01957 6.7e-60 ydiI Q Thioesterase superfamily
NAFHOKKD_01958 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NAFHOKKD_01959 6.3e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NAFHOKKD_01960 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NAFHOKKD_01961 2.8e-31 feoA P FeoA domain
NAFHOKKD_01962 3.2e-144 sufC O FeS assembly ATPase SufC
NAFHOKKD_01963 1.1e-239 sufD O FeS assembly protein SufD
NAFHOKKD_01964 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NAFHOKKD_01965 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
NAFHOKKD_01966 1.2e-271 sufB O assembly protein SufB
NAFHOKKD_01967 2.8e-57 yitW S Iron-sulfur cluster assembly protein
NAFHOKKD_01968 5.2e-159 hipB K Helix-turn-helix
NAFHOKKD_01969 1.1e-113 nreC K PFAM regulatory protein LuxR
NAFHOKKD_01970 9.2e-39 S Cytochrome B5
NAFHOKKD_01971 2.7e-154 yitU 3.1.3.104 S hydrolase
NAFHOKKD_01972 1.4e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NAFHOKKD_01973 1.2e-147 f42a O Band 7 protein
NAFHOKKD_01974 2.8e-247 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NAFHOKKD_01975 2.8e-55 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NAFHOKKD_01976 1.6e-126 lytT K response regulator receiver
NAFHOKKD_01977 4.1e-66 lrgA S LrgA family
NAFHOKKD_01978 2.5e-79 lrgB M LrgB-like family
NAFHOKKD_01979 1.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NAFHOKKD_01980 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NAFHOKKD_01981 2.6e-186 galR K Periplasmic binding protein-like domain
NAFHOKKD_01982 0.0 rafA 3.2.1.22 G alpha-galactosidase
NAFHOKKD_01983 1.7e-25 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NAFHOKKD_01984 4.2e-11 T SpoVT / AbrB like domain
NAFHOKKD_01985 6.1e-182 M lysozyme activity
NAFHOKKD_01986 3.6e-18 S Bacteriophage holin family
NAFHOKKD_01987 4.8e-12
NAFHOKKD_01989 5.2e-276 GT2,GT4 LM gp58-like protein
NAFHOKKD_01990 8.4e-52
NAFHOKKD_01991 0.0 M Phage tail tape measure protein TP901
NAFHOKKD_01992 4.4e-32
NAFHOKKD_01993 9e-58
NAFHOKKD_01994 2.9e-71 S Phage tail tube protein, TTP
NAFHOKKD_01995 1.4e-44
NAFHOKKD_01996 4.3e-79
NAFHOKKD_01997 4.6e-58
NAFHOKKD_01998 3.6e-35
NAFHOKKD_01999 3e-166 S Phage major capsid protein E
NAFHOKKD_02000 8.9e-54
NAFHOKKD_02001 6.9e-52 S Domain of unknown function (DUF4355)
NAFHOKKD_02002 2.3e-90 S Phage Mu protein F like protein
NAFHOKKD_02003 4.7e-24 S Phage Mu protein F like protein
NAFHOKKD_02004 4.6e-29 S Cysteine protease Prp
NAFHOKKD_02005 2e-216 S Phage portal protein, SPP1 Gp6-like
NAFHOKKD_02006 7.1e-218 S Terminase-like family
NAFHOKKD_02007 1.8e-116 xtmA L Terminase small subunit
NAFHOKKD_02009 1.3e-63 S Domain of unknown function (DUF4417)
NAFHOKKD_02013 1.7e-37
NAFHOKKD_02014 2.5e-07
NAFHOKKD_02017 1.5e-63 rusA L Endodeoxyribonuclease RusA
NAFHOKKD_02018 1.1e-27
NAFHOKKD_02019 1.2e-11
NAFHOKKD_02021 3.2e-18
NAFHOKKD_02024 4.6e-54 S ORF6C domain
NAFHOKKD_02027 4.5e-56 dnaC 3.4.21.53 L IstB-like ATP binding protein
NAFHOKKD_02028 2.8e-57 L Psort location Cytoplasmic, score
NAFHOKKD_02029 2.2e-18 L Psort location Cytoplasmic, score
NAFHOKKD_02030 1.3e-110 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NAFHOKKD_02031 4.7e-163 recT L RecT family
NAFHOKKD_02036 1.8e-17
NAFHOKKD_02041 3e-25
NAFHOKKD_02042 9.9e-33 ps115 K Transcriptional regulator, Cro CI family
NAFHOKKD_02043 7.1e-21 E Zn peptidase
NAFHOKKD_02045 3.1e-19
NAFHOKKD_02046 4.1e-38
NAFHOKKD_02047 2.1e-34 S Domain of unknown function (DUF4393)
NAFHOKKD_02048 6.9e-19
NAFHOKKD_02049 1.3e-259 L Transposase
NAFHOKKD_02050 6.9e-209 L Belongs to the 'phage' integrase family
NAFHOKKD_02051 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NAFHOKKD_02052 3.2e-47 rpsJ J Involved in the binding of tRNA to the ribosomes
NAFHOKKD_02053 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NAFHOKKD_02054 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NAFHOKKD_02055 4.9e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NAFHOKKD_02056 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NAFHOKKD_02057 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NAFHOKKD_02058 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NAFHOKKD_02059 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NAFHOKKD_02060 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NAFHOKKD_02061 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
NAFHOKKD_02062 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NAFHOKKD_02063 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NAFHOKKD_02064 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NAFHOKKD_02065 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NAFHOKKD_02066 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NAFHOKKD_02067 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NAFHOKKD_02068 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NAFHOKKD_02069 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NAFHOKKD_02070 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NAFHOKKD_02071 2.9e-24 rpmD J Ribosomal protein L30
NAFHOKKD_02072 5.8e-63 rplO J Binds to the 23S rRNA
NAFHOKKD_02073 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NAFHOKKD_02074 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NAFHOKKD_02075 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NAFHOKKD_02076 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NAFHOKKD_02077 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NAFHOKKD_02078 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NAFHOKKD_02079 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAFHOKKD_02080 1.1e-62 rplQ J Ribosomal protein L17
NAFHOKKD_02081 3.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAFHOKKD_02082 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAFHOKKD_02083 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAFHOKKD_02084 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NAFHOKKD_02085 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NAFHOKKD_02086 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NAFHOKKD_02087 8e-140 IQ reductase
NAFHOKKD_02088 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
NAFHOKKD_02089 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NAFHOKKD_02090 9.7e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NAFHOKKD_02091 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NAFHOKKD_02092 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NAFHOKKD_02093 3.3e-203 camS S sex pheromone
NAFHOKKD_02094 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NAFHOKKD_02095 7.7e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NAFHOKKD_02096 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NAFHOKKD_02097 1.5e-186 yegS 2.7.1.107 G Lipid kinase
NAFHOKKD_02098 1e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NAFHOKKD_02099 0.0 lacS G Transporter
NAFHOKKD_02100 2.3e-28
NAFHOKKD_02101 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NAFHOKKD_02102 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NAFHOKKD_02103 4.4e-190 yeaN P Transporter, major facilitator family protein
NAFHOKKD_02104 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
NAFHOKKD_02105 2.7e-82 nrdI F Belongs to the NrdI family
NAFHOKKD_02106 1.6e-236 yhdP S Transporter associated domain
NAFHOKKD_02107 5.4e-153 ypdB V (ABC) transporter
NAFHOKKD_02108 1.3e-88 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
NAFHOKKD_02109 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
NAFHOKKD_02110 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
NAFHOKKD_02111 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
NAFHOKKD_02112 1.8e-161 S AI-2E family transporter
NAFHOKKD_02113 2.7e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NAFHOKKD_02114 2.4e-159
NAFHOKKD_02115 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NAFHOKKD_02116 3.6e-138 eutJ E Hsp70 protein
NAFHOKKD_02117 8.3e-159 K helix_turn_helix, arabinose operon control protein
NAFHOKKD_02118 5.7e-231 EGP Sugar (and other) transporter
NAFHOKKD_02119 1.9e-253 yfnA E Amino Acid
NAFHOKKD_02120 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NAFHOKKD_02121 1.5e-98 gmk2 2.7.4.8 F Guanylate kinase
NAFHOKKD_02122 2.1e-81 zur P Belongs to the Fur family
NAFHOKKD_02123 3.1e-17 3.2.1.14 GH18
NAFHOKKD_02124 1e-148
NAFHOKKD_02125 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
NAFHOKKD_02126 3.5e-94 K Transcriptional regulator (TetR family)
NAFHOKKD_02127 4e-221 V domain protein
NAFHOKKD_02128 7.8e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NAFHOKKD_02130 1.5e-34 S Transglycosylase associated protein
NAFHOKKD_02131 5.6e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NAFHOKKD_02132 1.1e-126 3.1.3.73 G phosphoglycerate mutase
NAFHOKKD_02133 4e-116 dedA S SNARE associated Golgi protein
NAFHOKKD_02134 0.0 helD 3.6.4.12 L DNA helicase
NAFHOKKD_02135 1.6e-36 Q pyridine nucleotide-disulphide oxidoreductase
NAFHOKKD_02136 2.5e-158 EG EamA-like transporter family
NAFHOKKD_02137 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NAFHOKKD_02138 1.8e-175 coaA 2.7.1.33 F Pantothenic acid kinase
NAFHOKKD_02139 9.5e-217 S cog cog1373
NAFHOKKD_02141 8.1e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NAFHOKKD_02142 1.3e-38 ykuJ S Protein of unknown function (DUF1797)
NAFHOKKD_02143 5.7e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NAFHOKKD_02144 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
NAFHOKKD_02145 1.6e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NAFHOKKD_02146 1.3e-279 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NAFHOKKD_02147 1.9e-18 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NAFHOKKD_02148 2.7e-39 ptsH G phosphocarrier protein HPR
NAFHOKKD_02149 1.9e-26
NAFHOKKD_02150 0.0 clpE O Belongs to the ClpA ClpB family
NAFHOKKD_02151 7e-99 S Pfam:DUF3816
NAFHOKKD_02152 6.8e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NAFHOKKD_02153 1.4e-116
NAFHOKKD_02154 1.2e-155 V ABC transporter, ATP-binding protein
NAFHOKKD_02155 6e-64 gntR1 K Transcriptional regulator, GntR family
NAFHOKKD_02156 1.2e-52 ponA V the current gene model (or a revised gene model) may contain a frame shift
NAFHOKKD_02157 4.4e-57 M Peptidase_C39 like family
NAFHOKKD_02158 2.1e-227 L COG3547 Transposase and inactivated derivatives
NAFHOKKD_02162 2.2e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NAFHOKKD_02163 1.5e-26 XK27_00515 D Glucan-binding protein C
NAFHOKKD_02164 4.2e-158 L transposase, IS605 OrfB family
NAFHOKKD_02165 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_02166 1.7e-35 ruvB 3.6.4.12 L four-way junction helicase activity
NAFHOKKD_02174 4.1e-11
NAFHOKKD_02188 4.7e-21 L Psort location Cytoplasmic, score
NAFHOKKD_02190 7.7e-15
NAFHOKKD_02193 6.5e-08 S Arc-like DNA binding domain
NAFHOKKD_02196 2.9e-11 S protein disulfide oxidoreductase activity
NAFHOKKD_02197 1.2e-10 E Zn peptidase
NAFHOKKD_02198 2.7e-78 L Belongs to the 'phage' integrase family
NAFHOKKD_02200 1.9e-20 fimA S Family of unknown function (DUF1028)
NAFHOKKD_02201 8.3e-180 pvdI Q Non-ribosomal peptide synthetase modules and related
NAFHOKKD_02202 4.6e-88 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAFHOKKD_02203 1.8e-77 Q cog cog1020
NAFHOKKD_02204 3.3e-39 EGP Major facilitator Superfamily
NAFHOKKD_02205 2.9e-08 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NAFHOKKD_02206 2.1e-85 L PFAM Integrase catalytic region
NAFHOKKD_02207 8.7e-42
NAFHOKKD_02209 3.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NAFHOKKD_02211 3.7e-154 P Belongs to the nlpA lipoprotein family
NAFHOKKD_02212 3.9e-12
NAFHOKKD_02213 1.2e-140 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NAFHOKKD_02214 1e-218 L Integrase core domain
NAFHOKKD_02215 1.6e-126 O Bacterial dnaA protein
NAFHOKKD_02216 1.4e-294 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NAFHOKKD_02217 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
NAFHOKKD_02218 1.4e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NAFHOKKD_02219 5.9e-22 S Protein of unknown function (DUF3042)
NAFHOKKD_02220 3.4e-67 yqhL P Rhodanese-like protein
NAFHOKKD_02221 5.6e-183 glk 2.7.1.2 G Glucokinase
NAFHOKKD_02222 2.2e-35 yqgQ S Bacterial protein of unknown function (DUF910)
NAFHOKKD_02223 4e-108 gluP 3.4.21.105 S Peptidase, S54 family
NAFHOKKD_02224 6.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NAFHOKKD_02225 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NAFHOKKD_02226 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NAFHOKKD_02227 0.0 S membrane
NAFHOKKD_02228 1.6e-67 yneR S Belongs to the HesB IscA family
NAFHOKKD_02232 1e-14 K Cro/C1-type HTH DNA-binding domain
NAFHOKKD_02237 1.7e-263 dtpT U amino acid peptide transporter
NAFHOKKD_02238 8.5e-148 yjjH S Calcineurin-like phosphoesterase
NAFHOKKD_02241 2.3e-108
NAFHOKKD_02242 1.4e-246 EGP Major facilitator Superfamily
NAFHOKKD_02243 1.2e-299 aspT P Predicted Permease Membrane Region
NAFHOKKD_02244 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NAFHOKKD_02245 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
NAFHOKKD_02246 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NAFHOKKD_02247 5.7e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NAFHOKKD_02248 0.0 yhgF K Tex-like protein N-terminal domain protein
NAFHOKKD_02249 8.1e-84 ydcK S Belongs to the SprT family
NAFHOKKD_02252 1.9e-309 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
NAFHOKKD_02253 5.4e-254 hsdM 2.1.1.72 V type I restriction-modification system
NAFHOKKD_02254 1.8e-108 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NAFHOKKD_02255 1.3e-70 K Putative DNA-binding domain
NAFHOKKD_02258 1e-10 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
NAFHOKKD_02259 5.9e-08 L Resolvase, N terminal domain
NAFHOKKD_02260 4e-54 L Resolvase, N terminal domain
NAFHOKKD_02262 6e-20
NAFHOKKD_02263 7.6e-129 L Belongs to the 'phage' integrase family
NAFHOKKD_02264 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_02265 6e-97 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NAFHOKKD_02266 1e-111 frnE Q DSBA-like thioredoxin domain
NAFHOKKD_02267 8.8e-164 I alpha/beta hydrolase fold
NAFHOKKD_02268 8.5e-20 K Helix-turn-helix XRE-family like proteins
NAFHOKKD_02269 3.3e-35 S Phage derived protein Gp49-like (DUF891)
NAFHOKKD_02271 8.9e-41 yrvD S Pfam:DUF1049
NAFHOKKD_02272 4.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
NAFHOKKD_02273 2.1e-90 ntd 2.4.2.6 F Nucleoside
NAFHOKKD_02274 7.7e-18
NAFHOKKD_02275 3.1e-124 S Alpha/beta hydrolase of unknown function (DUF915)
NAFHOKKD_02276 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NAFHOKKD_02277 3.1e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NAFHOKKD_02278 4.7e-260 G Major Facilitator
NAFHOKKD_02279 8.6e-91 K Transcriptional regulator, LacI family
NAFHOKKD_02280 3.3e-144 L COG2826 Transposase and inactivated derivatives, IS30 family
NAFHOKKD_02281 2.7e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NAFHOKKD_02282 6.2e-276 pepV 3.5.1.18 E dipeptidase PepV
NAFHOKKD_02283 7.3e-86 uspA T Belongs to the universal stress protein A family
NAFHOKKD_02284 4.1e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NAFHOKKD_02285 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
NAFHOKKD_02286 2.5e-112
NAFHOKKD_02287 8.7e-187 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NAFHOKKD_02288 3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NAFHOKKD_02289 2.3e-108 manA 5.3.1.8 G mannose-6-phosphate isomerase
NAFHOKKD_02290 9.6e-71 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NAFHOKKD_02291 2.4e-62 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NAFHOKKD_02292 2.1e-180
NAFHOKKD_02293 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NAFHOKKD_02294 5.8e-184 S Phosphotransferase system, EIIC
NAFHOKKD_02295 6.4e-30 L PFAM transposase IS200-family protein
NAFHOKKD_02296 2.5e-36 L PFAM transposase IS200-family protein
NAFHOKKD_02299 3.5e-144 metQ_4 P Belongs to the nlpA lipoprotein family
NAFHOKKD_02300 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NAFHOKKD_02301 8.7e-122 O Zinc-dependent metalloprotease
NAFHOKKD_02302 2.1e-48 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NAFHOKKD_02303 3.5e-121 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NAFHOKKD_02304 1.7e-148 L hmm pf00665
NAFHOKKD_02305 9.6e-56 L Helix-turn-helix domain
NAFHOKKD_02306 2.7e-43 L Helix-turn-helix domain
NAFHOKKD_02307 2.5e-39 S Cytochrome B5
NAFHOKKD_02308 5.1e-27
NAFHOKKD_02309 1.5e-45 S Phage regulatory protein Rha (Phage_pRha)
NAFHOKKD_02312 1.9e-07
NAFHOKKD_02315 8.9e-09 L DnaD domain protein
NAFHOKKD_02317 2.8e-64
NAFHOKKD_02319 1.3e-55
NAFHOKKD_02321 1.3e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NAFHOKKD_02322 6e-208 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NAFHOKKD_02323 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NAFHOKKD_02324 1.3e-35 ynzC S UPF0291 protein
NAFHOKKD_02325 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
NAFHOKKD_02326 1.6e-117 plsC 2.3.1.51 I Acyltransferase
NAFHOKKD_02327 3.5e-140 yabB 2.1.1.223 L Methyltransferase small domain
NAFHOKKD_02328 5.4e-49 yazA L GIY-YIG catalytic domain protein
NAFHOKKD_02329 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NAFHOKKD_02330 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
NAFHOKKD_02331 7.1e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NAFHOKKD_02332 4.1e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NAFHOKKD_02333 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NAFHOKKD_02334 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NAFHOKKD_02335 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
NAFHOKKD_02336 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NAFHOKKD_02337 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NAFHOKKD_02338 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NAFHOKKD_02339 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NAFHOKKD_02340 1.4e-215 nusA K Participates in both transcription termination and antitermination
NAFHOKKD_02341 1e-44 ylxR K Protein of unknown function (DUF448)
NAFHOKKD_02342 1.3e-48 ylxQ J ribosomal protein
NAFHOKKD_02343 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NAFHOKKD_02344 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NAFHOKKD_02345 4.2e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NAFHOKKD_02346 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NAFHOKKD_02347 7.6e-64
NAFHOKKD_02348 5.9e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NAFHOKKD_02349 3.9e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NAFHOKKD_02350 0.0 dnaK O Heat shock 70 kDa protein
NAFHOKKD_02351 1.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NAFHOKKD_02352 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NAFHOKKD_02353 6e-260 ytjP 3.5.1.18 E Dipeptidase
NAFHOKKD_02354 4.8e-274 arcD S C4-dicarboxylate anaerobic carrier
NAFHOKKD_02355 3e-181 yfeX P Peroxidase
NAFHOKKD_02356 8.9e-101 lsa S ABC transporter
NAFHOKKD_02357 2.2e-157 lsa S ABC transporter
NAFHOKKD_02358 3e-133 I alpha/beta hydrolase fold
NAFHOKKD_02359 4e-179 MA20_14895 S Conserved hypothetical protein 698
NAFHOKKD_02360 1.2e-94 S NADPH-dependent FMN reductase
NAFHOKKD_02361 3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NAFHOKKD_02362 3.1e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NAFHOKKD_02363 9.7e-231 mntH P H( )-stimulated, divalent metal cation uptake system
NAFHOKKD_02364 9.4e-79 Q Methyltransferase
NAFHOKKD_02365 9.1e-116 ktrA P domain protein
NAFHOKKD_02366 5.8e-239 ktrB P Potassium uptake protein
NAFHOKKD_02367 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NAFHOKKD_02368 1.3e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NAFHOKKD_02369 5.5e-222 G Glycosyl hydrolases family 8
NAFHOKKD_02370 1.7e-243 ydaM M Glycosyl transferase
NAFHOKKD_02372 1.4e-140
NAFHOKKD_02373 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
NAFHOKKD_02374 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NAFHOKKD_02375 1.1e-153 pstA P Phosphate transport system permease protein PstA
NAFHOKKD_02376 1.8e-151 pstC P probably responsible for the translocation of the substrate across the membrane
NAFHOKKD_02377 1.5e-158 pstS P Phosphate
NAFHOKKD_02378 5.3e-130 K Transcriptional regulatory protein, C-terminal domain protein
NAFHOKKD_02379 1.5e-17 K Transcriptional regulator, HxlR family
NAFHOKKD_02380 8.7e-187
NAFHOKKD_02381 7.5e-97 2.3.1.128 K acetyltransferase
NAFHOKKD_02382 1e-23
NAFHOKKD_02383 6.3e-102 V VanZ like family
NAFHOKKD_02384 5.9e-231 cycA E Amino acid permease
NAFHOKKD_02385 2.8e-84 perR P Belongs to the Fur family
NAFHOKKD_02386 7.9e-258 EGP Major facilitator Superfamily
NAFHOKKD_02387 1.8e-93 tag 3.2.2.20 L glycosylase
NAFHOKKD_02388 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NAFHOKKD_02389 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NAFHOKKD_02390 4.9e-41
NAFHOKKD_02391 3.5e-302 ytgP S Polysaccharide biosynthesis protein
NAFHOKKD_02392 1.5e-123 S Alpha beta hydrolase
NAFHOKKD_02393 1.8e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NAFHOKKD_02394 1.3e-97
NAFHOKKD_02396 1.3e-122 yciB M ErfK YbiS YcfS YnhG
NAFHOKKD_02397 1.1e-259 S Putative peptidoglycan binding domain
NAFHOKKD_02398 3.9e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NAFHOKKD_02399 1.6e-67
NAFHOKKD_02400 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NAFHOKKD_02401 8.9e-215 yttB EGP Major facilitator Superfamily
NAFHOKKD_02402 2.6e-101
NAFHOKKD_02403 1e-24
NAFHOKKD_02404 2.5e-172 scrR K Transcriptional regulator, LacI family
NAFHOKKD_02405 2.9e-235 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NAFHOKKD_02406 9.2e-50 czrA K Transcriptional regulator, ArsR family
NAFHOKKD_02407 2.5e-36
NAFHOKKD_02408 0.0 yhcA V ABC transporter, ATP-binding protein
NAFHOKKD_02409 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NAFHOKKD_02410 3.3e-168 hrtB V ABC transporter permease
NAFHOKKD_02411 3.7e-85 ygfC K transcriptional regulator (TetR family)
NAFHOKKD_02412 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NAFHOKKD_02413 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
NAFHOKKD_02414 2.7e-263 L PFAM Integrase catalytic region
NAFHOKKD_02415 7.8e-97 yslB S Protein of unknown function (DUF2507)
NAFHOKKD_02416 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NAFHOKKD_02417 1.3e-105 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NAFHOKKD_02418 3.8e-93 S Phosphoesterase
NAFHOKKD_02419 1.1e-74 ykuL S (CBS) domain
NAFHOKKD_02420 4.7e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NAFHOKKD_02421 3.4e-147 ykuT M mechanosensitive ion channel
NAFHOKKD_02422 9.8e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NAFHOKKD_02423 1.5e-29
NAFHOKKD_02424 7.5e-80 L Integrase core domain
NAFHOKKD_02425 1.5e-91 2.3.1.183 M Acetyltransferase GNAT family
NAFHOKKD_02426 1.7e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
NAFHOKKD_02427 5.6e-255 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NAFHOKKD_02428 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAFHOKKD_02429 5.7e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
NAFHOKKD_02430 1.7e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAFHOKKD_02432 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NAFHOKKD_02433 2.4e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NAFHOKKD_02434 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
NAFHOKKD_02435 8.9e-251 U Belongs to the purine-cytosine permease (2.A.39) family
NAFHOKKD_02436 4.4e-241 codA 3.5.4.1 F cytosine deaminase
NAFHOKKD_02437 8.7e-61 tesE Q hydratase
NAFHOKKD_02438 4.2e-28
NAFHOKKD_02442 6.5e-94
NAFHOKKD_02443 1.3e-291 U Psort location Cytoplasmic, score
NAFHOKKD_02444 1.5e-108
NAFHOKKD_02452 3e-25
NAFHOKKD_02454 2.1e-11 chpR T PFAM SpoVT AbrB
NAFHOKKD_02455 8.6e-28 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NAFHOKKD_02460 1.4e-14 radC E Belongs to the UPF0758 family
NAFHOKKD_02464 8.8e-43
NAFHOKKD_02465 1.5e-41 DJ addiction module toxin, RelE
NAFHOKKD_02469 3.2e-63
NAFHOKKD_02476 2.7e-08 lytE M LysM domain protein
NAFHOKKD_02477 1.1e-42 yciB M ErfK YbiS YcfS YnhG
NAFHOKKD_02478 1.9e-96 ypuA S Protein of unknown function (DUF1002)
NAFHOKKD_02480 8.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
NAFHOKKD_02482 1e-21 uhpT EGP Major facilitator Superfamily
NAFHOKKD_02483 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NAFHOKKD_02484 3.9e-145 potB P ABC transporter permease
NAFHOKKD_02485 6.5e-140 potC P ABC transporter permease
NAFHOKKD_02486 1.8e-206 potD P ABC transporter
NAFHOKKD_02487 9.5e-67 ltrA S Bacterial low temperature requirement A protein (LtrA)
NAFHOKKD_02488 3.4e-43 ltrA S Bacterial low temperature requirement A protein (LtrA)
NAFHOKKD_02489 1.6e-79 uspA T universal stress protein
NAFHOKKD_02490 2e-77 K AsnC family
NAFHOKKD_02491 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NAFHOKKD_02492 6.3e-103 dedA 3.1.3.1 S SNARE associated Golgi protein
NAFHOKKD_02494 1.3e-260 S Putative peptidoglycan binding domain
NAFHOKKD_02495 2.3e-39
NAFHOKKD_02496 1.7e-213 bacI V MacB-like periplasmic core domain
NAFHOKKD_02497 2.8e-128 V ABC transporter
NAFHOKKD_02498 3.7e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NAFHOKKD_02499 3.7e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NAFHOKKD_02500 1.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NAFHOKKD_02501 1.2e-148 E Glyoxalase-like domain
NAFHOKKD_02502 7.5e-155 glcU U sugar transport
NAFHOKKD_02503 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NAFHOKKD_02504 7.1e-95 S reductase
NAFHOKKD_02506 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NAFHOKKD_02507 8.5e-179 ABC-SBP S ABC transporter
NAFHOKKD_02508 4.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NAFHOKKD_02509 4.7e-214 htrA 3.4.21.107 O serine protease
NAFHOKKD_02510 2.3e-153 vicX 3.1.26.11 S domain protein
NAFHOKKD_02511 7.8e-149 yycI S YycH protein
NAFHOKKD_02512 9e-245 yycH S YycH protein
NAFHOKKD_02513 0.0 vicK 2.7.13.3 T Histidine kinase
NAFHOKKD_02514 3.1e-130 K response regulator
NAFHOKKD_02516 2.2e-307 lmrA 3.6.3.44 V ABC transporter
NAFHOKKD_02517 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
NAFHOKKD_02519 7.5e-96 Z012_01130 S Fic/DOC family
NAFHOKKD_02521 6.9e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NAFHOKKD_02522 9.1e-61
NAFHOKKD_02523 9e-207 yttB EGP Major facilitator Superfamily
NAFHOKKD_02524 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NAFHOKKD_02525 2e-74 rplI J Binds to the 23S rRNA
NAFHOKKD_02526 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NAFHOKKD_02527 2.6e-100 deoR K sugar-binding domain protein
NAFHOKKD_02528 2.4e-74 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NAFHOKKD_02529 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NAFHOKKD_02530 2.8e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NAFHOKKD_02531 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NAFHOKKD_02532 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NAFHOKKD_02533 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NAFHOKKD_02534 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NAFHOKKD_02535 3.8e-34 yaaA S S4 domain protein YaaA
NAFHOKKD_02536 2e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NAFHOKKD_02537 5.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NAFHOKKD_02538 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NAFHOKKD_02539 6e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NAFHOKKD_02540 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NAFHOKKD_02541 6.3e-129 jag S R3H domain protein
NAFHOKKD_02542 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NAFHOKKD_02543 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NAFHOKKD_02544 0.0 asnB 6.3.5.4 E Asparagine synthase
NAFHOKKD_02545 1.4e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NAFHOKKD_02546 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
NAFHOKKD_02547 3e-85
NAFHOKKD_02548 1.3e-168 L Belongs to the 'phage' integrase family
NAFHOKKD_02549 3.1e-19 S Excisionase from transposon Tn916
NAFHOKKD_02552 3.3e-133
NAFHOKKD_02553 1.1e-12 S Helix-turn-helix domain
NAFHOKKD_02555 2.5e-77 L Resolvase, N terminal domain
NAFHOKKD_02556 1e-10 L Resolvase, N terminal domain
NAFHOKKD_02557 1e-10 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
NAFHOKKD_02561 1.1e-48 ebh D nuclear chromosome segregation
NAFHOKKD_02562 9e-17 K Cro/C1-type HTH DNA-binding domain
NAFHOKKD_02563 1.6e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NAFHOKKD_02564 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NAFHOKKD_02565 3.3e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NAFHOKKD_02566 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NAFHOKKD_02567 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NAFHOKKD_02568 1.4e-251 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NAFHOKKD_02569 9.8e-67 yabR J RNA binding
NAFHOKKD_02570 8.1e-55 divIC D Septum formation initiator
NAFHOKKD_02571 2.1e-39 yabO J S4 domain protein
NAFHOKKD_02572 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NAFHOKKD_02573 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NAFHOKKD_02574 1.4e-113 S (CBS) domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)