ORF_ID e_value Gene_name EC_number CAZy COGs Description
GPHLGPHH_00011 8.8e-15
GPHLGPHH_00013 1.5e-169 whiA K May be required for sporulation
GPHLGPHH_00014 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GPHLGPHH_00015 4.9e-162 rapZ S Displays ATPase and GTPase activities
GPHLGPHH_00016 1e-243 steT E amino acid
GPHLGPHH_00017 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GPHLGPHH_00018 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GPHLGPHH_00019 6.9e-14
GPHLGPHH_00020 1.1e-115 yfbR S HD containing hydrolase-like enzyme
GPHLGPHH_00021 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GPHLGPHH_00022 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
GPHLGPHH_00023 8.5e-162 aatB ET PFAM extracellular solute-binding protein, family 3
GPHLGPHH_00024 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GPHLGPHH_00025 5.6e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GPHLGPHH_00026 2.7e-168 lutA C Cysteine-rich domain
GPHLGPHH_00027 1.7e-292 lutB C 4Fe-4S dicluster domain
GPHLGPHH_00028 4.6e-137 yrjD S LUD domain
GPHLGPHH_00029 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPHLGPHH_00030 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GPHLGPHH_00031 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPHLGPHH_00032 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GPHLGPHH_00033 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
GPHLGPHH_00034 7.7e-31 KT PspC domain protein
GPHLGPHH_00035 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GPHLGPHH_00036 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPHLGPHH_00039 1.2e-11
GPHLGPHH_00040 4.6e-45 D nuclear chromosome segregation
GPHLGPHH_00042 5.7e-11 K Cro/C1-type HTH DNA-binding domain
GPHLGPHH_00048 3.7e-205 amtB P ammonium transporter
GPHLGPHH_00049 6.8e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
GPHLGPHH_00050 8.6e-84 yvbK 3.1.3.25 K GNAT family
GPHLGPHH_00051 1.7e-91
GPHLGPHH_00052 4.1e-121 pnb C nitroreductase
GPHLGPHH_00053 2.4e-75 ogt 2.1.1.63 L Methyltransferase
GPHLGPHH_00054 1.8e-154 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
GPHLGPHH_00055 6.8e-67 S Protein of unknown function (DUF3021)
GPHLGPHH_00056 3.5e-76 K LytTr DNA-binding domain
GPHLGPHH_00057 1.1e-92 K Acetyltransferase (GNAT) family
GPHLGPHH_00058 2.9e-74 L An automated process has identified a potential problem with this gene model
GPHLGPHH_00059 6.7e-191 L Transposase IS66 family
GPHLGPHH_00060 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_00062 5.5e-38 S D5 N terminal like
GPHLGPHH_00067 3.5e-88 K Transcriptional regulator
GPHLGPHH_00068 4e-140 akr5f 1.1.1.346 S reductase
GPHLGPHH_00069 8.3e-110 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPHLGPHH_00070 7.2e-144 C Aldo keto reductase
GPHLGPHH_00071 3.3e-118 GM NmrA-like family
GPHLGPHH_00072 1.1e-124 EGP Major facilitator Superfamily
GPHLGPHH_00073 3e-74 ltrA S Bacterial low temperature requirement A protein (LtrA)
GPHLGPHH_00075 8.7e-27 EGP Major Facilitator Superfamily
GPHLGPHH_00076 1.3e-105 C Aldo/keto reductase family
GPHLGPHH_00077 8e-62 yphH S Cupin domain
GPHLGPHH_00078 2.8e-46 yphJ 4.1.1.44 S decarboxylase
GPHLGPHH_00079 3.2e-181 L Transposase DDE domain
GPHLGPHH_00080 2.9e-74 L An automated process has identified a potential problem with this gene model
GPHLGPHH_00081 6.7e-191 L Transposase IS66 family
GPHLGPHH_00082 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_00084 1e-15 fhaB M Rib/alpha-like repeat
GPHLGPHH_00086 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_00087 6.7e-191 L Transposase IS66 family
GPHLGPHH_00088 2.9e-74 L An automated process has identified a potential problem with this gene model
GPHLGPHH_00089 1.4e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
GPHLGPHH_00090 7.6e-139 epsB M biosynthesis protein
GPHLGPHH_00091 2.1e-161 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GPHLGPHH_00092 2e-40 K Transcriptional regulator, HxlR family
GPHLGPHH_00094 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_00095 6.7e-191 L Transposase IS66 family
GPHLGPHH_00096 2.9e-74 L An automated process has identified a potential problem with this gene model
GPHLGPHH_00097 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GPHLGPHH_00098 2.3e-13
GPHLGPHH_00099 4.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
GPHLGPHH_00100 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
GPHLGPHH_00101 5e-34
GPHLGPHH_00102 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GPHLGPHH_00103 9.9e-261 yfnA E amino acid
GPHLGPHH_00104 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GPHLGPHH_00105 5e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPHLGPHH_00106 4.1e-40 ylqC S Belongs to the UPF0109 family
GPHLGPHH_00107 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GPHLGPHH_00108 2.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPHLGPHH_00109 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GPHLGPHH_00110 8.5e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPHLGPHH_00111 0.0 smc D Required for chromosome condensation and partitioning
GPHLGPHH_00112 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GPHLGPHH_00113 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPHLGPHH_00114 6.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GPHLGPHH_00115 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPHLGPHH_00116 0.0 yloV S DAK2 domain fusion protein YloV
GPHLGPHH_00117 4.7e-58 asp S Asp23 family, cell envelope-related function
GPHLGPHH_00118 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GPHLGPHH_00119 2.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
GPHLGPHH_00120 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GPHLGPHH_00121 4.2e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GPHLGPHH_00122 0.0 KLT serine threonine protein kinase
GPHLGPHH_00123 2.1e-129 stp 3.1.3.16 T phosphatase
GPHLGPHH_00124 5e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPHLGPHH_00125 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPHLGPHH_00126 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPHLGPHH_00127 3.1e-207 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPHLGPHH_00128 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GPHLGPHH_00129 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GPHLGPHH_00130 4.2e-53
GPHLGPHH_00131 6.1e-262 recN L May be involved in recombinational repair of damaged DNA
GPHLGPHH_00132 7.3e-77 argR K Regulates arginine biosynthesis genes
GPHLGPHH_00133 1.2e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GPHLGPHH_00134 4.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPHLGPHH_00135 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPHLGPHH_00136 2.9e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPHLGPHH_00137 1.3e-146 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPHLGPHH_00138 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPHLGPHH_00139 2.2e-70 yqhY S Asp23 family, cell envelope-related function
GPHLGPHH_00140 1.7e-114 J 2'-5' RNA ligase superfamily
GPHLGPHH_00141 7.3e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GPHLGPHH_00142 2.6e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPHLGPHH_00143 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GPHLGPHH_00144 2.4e-53 ysxB J Cysteine protease Prp
GPHLGPHH_00145 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
GPHLGPHH_00146 7e-110 K Transcriptional regulator
GPHLGPHH_00149 5.7e-86 dut S Protein conserved in bacteria
GPHLGPHH_00150 3e-179
GPHLGPHH_00151 9.7e-150
GPHLGPHH_00152 4.8e-51 S Iron-sulfur cluster assembly protein
GPHLGPHH_00153 4.7e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPHLGPHH_00154 3.9e-12
GPHLGPHH_00155 3.2e-181 L Transposase DDE domain
GPHLGPHH_00157 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_00158 6.7e-191 L Transposase IS66 family
GPHLGPHH_00159 2.9e-74 L An automated process has identified a potential problem with this gene model
GPHLGPHH_00164 6.9e-44 L Belongs to the 'phage' integrase family
GPHLGPHH_00165 5.5e-130 dprA LU DNA protecting protein DprA
GPHLGPHH_00166 5.1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPHLGPHH_00167 1.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPHLGPHH_00168 4.4e-35 yozE S Belongs to the UPF0346 family
GPHLGPHH_00169 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
GPHLGPHH_00170 3.7e-168 ypmR E lipolytic protein G-D-S-L family
GPHLGPHH_00171 7.1e-150 DegV S EDD domain protein, DegV family
GPHLGPHH_00172 1.3e-111 hlyIII S protein, hemolysin III
GPHLGPHH_00173 1.6e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPHLGPHH_00174 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPHLGPHH_00175 0.0 yfmR S ABC transporter, ATP-binding protein
GPHLGPHH_00176 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPHLGPHH_00177 2.6e-233 S Tetratricopeptide repeat protein
GPHLGPHH_00178 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPHLGPHH_00179 4.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GPHLGPHH_00180 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
GPHLGPHH_00181 1.7e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GPHLGPHH_00182 2.5e-13 M Lysin motif
GPHLGPHH_00183 7.1e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
GPHLGPHH_00184 6.7e-195 ypbB 5.1.3.1 S Helix-turn-helix domain
GPHLGPHH_00185 5.5e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPHLGPHH_00188 7.7e-10 E Collagen triple helix repeat (20 copies)
GPHLGPHH_00190 9.9e-136 lysA2 M Glycosyl hydrolases family 25
GPHLGPHH_00191 3.9e-34 S Bacteriophage holin of superfamily 6 (Holin_LLH)
GPHLGPHH_00192 1.9e-39
GPHLGPHH_00193 8.2e-12
GPHLGPHH_00194 9.4e-62 S Domain of unknown function (DUF2479)
GPHLGPHH_00195 1.2e-75 3.2.1.11 GH66 G Cycloisomaltooligosaccharide glucanotransferase
GPHLGPHH_00197 4.3e-28
GPHLGPHH_00198 4.5e-290 M Prophage endopeptidase tail
GPHLGPHH_00199 3e-140 S Phage tail protein
GPHLGPHH_00200 0.0 M Phage tail tape measure protein TP901
GPHLGPHH_00201 3.7e-67
GPHLGPHH_00202 3.9e-133 S Phage tail tube protein
GPHLGPHH_00203 8.7e-71
GPHLGPHH_00204 1.9e-83
GPHLGPHH_00205 1.2e-63 S Phage head-tail joining protein
GPHLGPHH_00206 2.1e-60 S Phage gp6-like head-tail connector protein
GPHLGPHH_00208 2.8e-213 S Phage capsid family
GPHLGPHH_00209 2.8e-137 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
GPHLGPHH_00210 4.3e-247 S portal protein
GPHLGPHH_00211 2.9e-262 L Terminase
GPHLGPHH_00212 5.7e-88 L Terminase
GPHLGPHH_00213 1.8e-78 L Phage terminase, small subunit
GPHLGPHH_00214 2.1e-52 L HNH nucleases
GPHLGPHH_00228 4e-24 V HNH endonuclease
GPHLGPHH_00230 2.7e-38 S HicB_like antitoxin of bacterial toxin-antitoxin system
GPHLGPHH_00235 1.6e-102 pnuC H nicotinamide mononucleotide transporter
GPHLGPHH_00236 1.7e-35 L NUMOD4 motif
GPHLGPHH_00245 2.3e-208 XK27_11280 S Psort location CytoplasmicMembrane, score
GPHLGPHH_00246 0.0
GPHLGPHH_00248 7.1e-74 S Transcriptional regulator, RinA family
GPHLGPHH_00253 8.9e-130 dck 2.7.1.74 F deoxynucleoside kinase
GPHLGPHH_00259 3.6e-132
GPHLGPHH_00263 2e-68 Q DNA (cytosine-5-)-methyltransferase activity
GPHLGPHH_00269 6.6e-78 rusA L Endodeoxyribonuclease RusA
GPHLGPHH_00270 1.9e-35
GPHLGPHH_00271 8.9e-21
GPHLGPHH_00275 1.9e-129 L Psort location Cytoplasmic, score
GPHLGPHH_00276 1.1e-132 S Putative HNHc nuclease
GPHLGPHH_00277 2e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPHLGPHH_00279 2.9e-07
GPHLGPHH_00283 4.1e-08
GPHLGPHH_00285 5.6e-111 S Protein of unknown function (DUF3102)
GPHLGPHH_00286 1.3e-20
GPHLGPHH_00289 1.8e-48 K addiction module antidote protein HigA
GPHLGPHH_00290 2.9e-73 E IrrE N-terminal-like domain
GPHLGPHH_00294 1.6e-70 L Belongs to the 'phage' integrase family
GPHLGPHH_00295 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPHLGPHH_00296 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GPHLGPHH_00297 7.1e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GPHLGPHH_00298 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPHLGPHH_00299 9.1e-164 xerD D recombinase XerD
GPHLGPHH_00300 9.3e-169 cvfB S S1 domain
GPHLGPHH_00301 1.4e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GPHLGPHH_00302 0.0 dnaE 2.7.7.7 L DNA polymerase
GPHLGPHH_00303 2e-29 S Protein of unknown function (DUF2929)
GPHLGPHH_00304 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GPHLGPHH_00305 8.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPHLGPHH_00306 4.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
GPHLGPHH_00307 2.4e-220 patA 2.6.1.1 E Aminotransferase
GPHLGPHH_00308 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GPHLGPHH_00309 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GPHLGPHH_00310 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GPHLGPHH_00311 2.9e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GPHLGPHH_00312 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
GPHLGPHH_00313 1.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPHLGPHH_00314 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GPHLGPHH_00315 1.2e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPHLGPHH_00316 4.5e-183 phoH T phosphate starvation-inducible protein PhoH
GPHLGPHH_00317 2.1e-169 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GPHLGPHH_00318 3.8e-83 bioY S BioY family
GPHLGPHH_00319 3.3e-236 L Transposase
GPHLGPHH_00320 0.0 trxB2 1.8.1.9 C Thioredoxin domain
GPHLGPHH_00321 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
GPHLGPHH_00322 9.7e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GPHLGPHH_00323 1.3e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
GPHLGPHH_00326 9.3e-185 L transposase, IS605 OrfB family
GPHLGPHH_00327 3.2e-34 L Transposase IS200 like
GPHLGPHH_00328 1.6e-238 L Integrase core domain
GPHLGPHH_00329 3.4e-98 epsB M biosynthesis protein
GPHLGPHH_00330 1.7e-107 ywqD 2.7.10.1 D Capsular exopolysaccharide family
GPHLGPHH_00331 8.9e-49 pglC M Bacterial sugar transferase
GPHLGPHH_00332 1.2e-86 GT4 G Glycosyl transferase 4-like
GPHLGPHH_00333 8e-68 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
GPHLGPHH_00334 1.4e-42 GT2,GT4 M Glycosyltransferase GT-D fold
GPHLGPHH_00336 9.7e-73 cps2I S Psort location CytoplasmicMembrane, score
GPHLGPHH_00337 5.1e-35 M Glycosyltransferase sugar-binding region containing DXD motif
GPHLGPHH_00338 4.7e-28 M Glycosyltransferase like family 2
GPHLGPHH_00339 2.7e-28 S COG0463 Glycosyltransferases involved in cell wall biogenesis
GPHLGPHH_00340 1.9e-49 S Glycosyltransferase like family 2
GPHLGPHH_00342 2.6e-29 S Acyltransferase family
GPHLGPHH_00343 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
GPHLGPHH_00344 1.6e-238 L Integrase core domain
GPHLGPHH_00345 4.3e-34 S C4-dicarboxylate anaerobic carrier
GPHLGPHH_00346 2.9e-70 IQ Enoyl-(Acyl carrier protein) reductase
GPHLGPHH_00347 4.6e-36 K Bacterial transcriptional regulator
GPHLGPHH_00348 2.7e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
GPHLGPHH_00349 1.2e-39
GPHLGPHH_00350 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GPHLGPHH_00351 1.1e-206 gldA 1.1.1.6 C dehydrogenase
GPHLGPHH_00352 2.1e-114 L transposase IS116 IS110 IS902 family protein
GPHLGPHH_00353 4.5e-82 L transposase IS116 IS110 IS902 family protein
GPHLGPHH_00354 2.2e-38 S Alpha beta hydrolase
GPHLGPHH_00355 1.5e-63 S Alpha beta hydrolase
GPHLGPHH_00356 5.3e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPHLGPHH_00357 4.8e-97
GPHLGPHH_00359 1.3e-122 yciB M ErfK YbiS YcfS YnhG
GPHLGPHH_00360 3.6e-260 S Putative peptidoglycan binding domain
GPHLGPHH_00361 1.5e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
GPHLGPHH_00362 3.6e-85
GPHLGPHH_00363 1.5e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
GPHLGPHH_00364 4.9e-213 yttB EGP Major facilitator Superfamily
GPHLGPHH_00365 1e-100
GPHLGPHH_00366 1e-24
GPHLGPHH_00367 1.8e-173 scrR K Transcriptional regulator, LacI family
GPHLGPHH_00368 6.3e-38 ykuJ S Protein of unknown function (DUF1797)
GPHLGPHH_00369 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPHLGPHH_00370 6.5e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
GPHLGPHH_00371 2.1e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GPHLGPHH_00372 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPHLGPHH_00373 2.7e-39 ptsH G phosphocarrier protein HPR
GPHLGPHH_00374 6.4e-27
GPHLGPHH_00375 0.0 clpE O Belongs to the ClpA ClpB family
GPHLGPHH_00376 1.7e-100 S Pfam:DUF3816
GPHLGPHH_00377 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
GPHLGPHH_00378 5.5e-116
GPHLGPHH_00379 4.4e-155 V ABC transporter, ATP-binding protein
GPHLGPHH_00380 6e-64 gntR1 K Transcriptional regulator, GntR family
GPHLGPHH_00381 0.0 bamA GM domain, Protein
GPHLGPHH_00382 0.0 S Peptidase, M23
GPHLGPHH_00383 0.0 M NlpC/P60 family
GPHLGPHH_00384 3.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPHLGPHH_00385 1.5e-224 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GPHLGPHH_00386 7.4e-163 yueF S AI-2E family transporter
GPHLGPHH_00387 0.0 csd1 3.5.1.28 G domain, Protein
GPHLGPHH_00388 2.1e-24
GPHLGPHH_00389 9.5e-59
GPHLGPHH_00390 1.3e-70
GPHLGPHH_00391 9.3e-32
GPHLGPHH_00392 9.8e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
GPHLGPHH_00393 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GPHLGPHH_00394 3.1e-101 fic D Fic/DOC family
GPHLGPHH_00395 2.8e-70
GPHLGPHH_00396 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
GPHLGPHH_00397 1e-87 L nuclease
GPHLGPHH_00398 0.0 sbcC L Putative exonuclease SbcCD, C subunit
GPHLGPHH_00399 6.8e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GPHLGPHH_00400 1e-142 ywqE 3.1.3.48 GM PHP domain protein
GPHLGPHH_00401 0.0 snf 2.7.11.1 KL domain protein
GPHLGPHH_00402 6.7e-07 D nuclear chromosome segregation
GPHLGPHH_00403 5.2e-37
GPHLGPHH_00404 7.4e-67 T Toxin-antitoxin system, toxin component, MazF family
GPHLGPHH_00406 2.5e-248 mmuP E amino acid
GPHLGPHH_00407 4.7e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
GPHLGPHH_00408 9.3e-185 L transposase, IS605 OrfB family
GPHLGPHH_00409 3.2e-34 L Transposase IS200 like
GPHLGPHH_00410 3.3e-236 L Transposase
GPHLGPHH_00411 1.1e-56 ytzB S Small secreted protein
GPHLGPHH_00412 1.8e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GPHLGPHH_00413 9.4e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPHLGPHH_00414 1.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GPHLGPHH_00415 1.4e-119 ybhL S Belongs to the BI1 family
GPHLGPHH_00416 2.4e-72 yoaK S Protein of unknown function (DUF1275)
GPHLGPHH_00417 1e-15 yoaK S Protein of unknown function (DUF1275)
GPHLGPHH_00418 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPHLGPHH_00419 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GPHLGPHH_00420 5e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPHLGPHH_00421 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPHLGPHH_00422 1.9e-221 dnaB L replication initiation and membrane attachment
GPHLGPHH_00423 1.9e-172 dnaI L Primosomal protein DnaI
GPHLGPHH_00424 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPHLGPHH_00425 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GPHLGPHH_00426 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPHLGPHH_00427 3.3e-236 L Transposase
GPHLGPHH_00428 3.5e-263 argH 4.3.2.1 E argininosuccinate lyase
GPHLGPHH_00429 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPHLGPHH_00430 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GPHLGPHH_00431 8.6e-70 yqeY S YqeY-like protein
GPHLGPHH_00432 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GPHLGPHH_00433 1.1e-262 glnPH2 P ABC transporter permease
GPHLGPHH_00434 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPHLGPHH_00435 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GPHLGPHH_00436 9.3e-166 yniA G Phosphotransferase enzyme family
GPHLGPHH_00437 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPHLGPHH_00438 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPHLGPHH_00439 9.4e-50
GPHLGPHH_00440 1.5e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GPHLGPHH_00441 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
GPHLGPHH_00442 7.5e-58
GPHLGPHH_00443 5.7e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPHLGPHH_00445 5.2e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
GPHLGPHH_00446 2e-274 pipD E Dipeptidase
GPHLGPHH_00447 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GPHLGPHH_00448 2.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GPHLGPHH_00449 0.0 dnaK O Heat shock 70 kDa protein
GPHLGPHH_00450 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPHLGPHH_00451 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GPHLGPHH_00452 2.9e-63
GPHLGPHH_00453 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GPHLGPHH_00454 7.1e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPHLGPHH_00455 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPHLGPHH_00456 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPHLGPHH_00457 1.3e-48 ylxQ J ribosomal protein
GPHLGPHH_00458 1e-44 ylxR K Protein of unknown function (DUF448)
GPHLGPHH_00459 2.3e-215 nusA K Participates in both transcription termination and antitermination
GPHLGPHH_00460 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
GPHLGPHH_00461 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPHLGPHH_00462 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GPHLGPHH_00463 1.8e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GPHLGPHH_00464 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
GPHLGPHH_00465 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPHLGPHH_00466 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GPHLGPHH_00467 7.7e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GPHLGPHH_00468 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPHLGPHH_00469 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
GPHLGPHH_00470 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPHLGPHH_00471 7.1e-49 yazA L GIY-YIG catalytic domain protein
GPHLGPHH_00472 2.7e-140 yabB 2.1.1.223 L Methyltransferase small domain
GPHLGPHH_00473 4.6e-117 plsC 2.3.1.51 I Acyltransferase
GPHLGPHH_00474 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
GPHLGPHH_00475 1.3e-35 ynzC S UPF0291 protein
GPHLGPHH_00476 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPHLGPHH_00477 3.2e-209 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
GPHLGPHH_00478 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPHLGPHH_00480 4.8e-87
GPHLGPHH_00481 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPHLGPHH_00482 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GPHLGPHH_00483 2.1e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPHLGPHH_00484 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GPHLGPHH_00485 9.7e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPHLGPHH_00486 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPHLGPHH_00487 4.9e-08
GPHLGPHH_00488 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
GPHLGPHH_00489 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
GPHLGPHH_00490 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPHLGPHH_00491 1.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GPHLGPHH_00492 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPHLGPHH_00493 1.6e-163 S Tetratricopeptide repeat
GPHLGPHH_00494 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPHLGPHH_00495 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPHLGPHH_00496 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
GPHLGPHH_00497 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
GPHLGPHH_00498 0.0 comEC S Competence protein ComEC
GPHLGPHH_00499 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
GPHLGPHH_00500 5.8e-80 comEA L Competence protein ComEA
GPHLGPHH_00501 1.3e-196 ylbL T Belongs to the peptidase S16 family
GPHLGPHH_00502 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPHLGPHH_00503 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
GPHLGPHH_00504 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
GPHLGPHH_00505 2.7e-222 ftsW D Belongs to the SEDS family
GPHLGPHH_00506 0.0 typA T GTP-binding protein TypA
GPHLGPHH_00507 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GPHLGPHH_00508 3.7e-45 yktA S Belongs to the UPF0223 family
GPHLGPHH_00509 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
GPHLGPHH_00510 1.7e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPHLGPHH_00511 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
GPHLGPHH_00512 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GPHLGPHH_00513 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPHLGPHH_00514 4.8e-79
GPHLGPHH_00515 9.8e-32 ykzG S Belongs to the UPF0356 family
GPHLGPHH_00516 3.3e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
GPHLGPHH_00517 5.7e-29
GPHLGPHH_00518 3.8e-130 mltD CBM50 M NlpC P60 family protein
GPHLGPHH_00520 2.2e-57
GPHLGPHH_00521 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GPHLGPHH_00522 4.2e-218 EG GntP family permease
GPHLGPHH_00523 8.5e-84 KT Putative sugar diacid recognition
GPHLGPHH_00524 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPHLGPHH_00525 7.7e-219 patA 2.6.1.1 E Aminotransferase
GPHLGPHH_00526 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GPHLGPHH_00527 2.9e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPHLGPHH_00528 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GPHLGPHH_00529 7e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GPHLGPHH_00530 1.5e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GPHLGPHH_00531 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
GPHLGPHH_00532 1.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPHLGPHH_00533 6.9e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPHLGPHH_00534 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GPHLGPHH_00535 4.9e-117 S Repeat protein
GPHLGPHH_00536 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
GPHLGPHH_00537 6.9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GPHLGPHH_00538 7.5e-58 XK27_04120 S Putative amino acid metabolism
GPHLGPHH_00539 1.6e-216 iscS 2.8.1.7 E Aminotransferase class V
GPHLGPHH_00540 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPHLGPHH_00542 4.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
GPHLGPHH_00543 4.2e-32 cspA K Cold shock protein
GPHLGPHH_00544 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPHLGPHH_00545 1.3e-35 divIVA D DivIVA domain protein
GPHLGPHH_00546 2.4e-144 ylmH S S4 domain protein
GPHLGPHH_00547 3.2e-40 yggT S YGGT family
GPHLGPHH_00548 2.1e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GPHLGPHH_00549 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPHLGPHH_00550 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GPHLGPHH_00551 2.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GPHLGPHH_00552 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPHLGPHH_00553 4.2e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPHLGPHH_00554 4.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPHLGPHH_00555 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GPHLGPHH_00556 2.9e-55 ftsL D Cell division protein FtsL
GPHLGPHH_00557 8.8e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GPHLGPHH_00558 3.1e-77 mraZ K Belongs to the MraZ family
GPHLGPHH_00559 1.7e-57
GPHLGPHH_00560 1.2e-10 S Protein of unknown function (DUF4044)
GPHLGPHH_00561 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GPHLGPHH_00562 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GPHLGPHH_00563 1.4e-158 rrmA 2.1.1.187 H Methyltransferase
GPHLGPHH_00564 5e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GPHLGPHH_00566 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_00567 2.5e-09 L Transposase IS66 family
GPHLGPHH_00568 4.2e-109 L Bacterial dnaA protein
GPHLGPHH_00569 2.6e-137 L Integrase core domain
GPHLGPHH_00570 2.6e-149 L Transposase IS66 family
GPHLGPHH_00571 3.3e-236 L Transposase
GPHLGPHH_00572 2.6e-11 glsA 3.5.1.2 E Belongs to the glutaminase family
GPHLGPHH_00573 1.3e-64 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
GPHLGPHH_00574 1.3e-12 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
GPHLGPHH_00575 9.5e-16 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
GPHLGPHH_00576 2.5e-16 S YSIRK type signal peptide
GPHLGPHH_00577 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GPHLGPHH_00578 3.9e-218 ecsB U ABC transporter
GPHLGPHH_00579 6.7e-136 ecsA V ABC transporter, ATP-binding protein
GPHLGPHH_00580 1.2e-76 hit FG histidine triad
GPHLGPHH_00582 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GPHLGPHH_00583 0.0 L AAA domain
GPHLGPHH_00584 2.8e-221 yhaO L Ser Thr phosphatase family protein
GPHLGPHH_00585 9.4e-38 yheA S Belongs to the UPF0342 family
GPHLGPHH_00586 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPHLGPHH_00587 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GPHLGPHH_00588 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPHLGPHH_00589 5.6e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPHLGPHH_00591 1.6e-39
GPHLGPHH_00592 5.1e-43
GPHLGPHH_00593 6e-208 folP 2.5.1.15 H dihydropteroate synthase
GPHLGPHH_00594 1.1e-101 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
GPHLGPHH_00595 1.1e-220 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GPHLGPHH_00596 1.2e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
GPHLGPHH_00597 1.1e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GPHLGPHH_00598 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPHLGPHH_00599 8.4e-69
GPHLGPHH_00601 2.5e-43
GPHLGPHH_00602 2.7e-109 S CAAX protease self-immunity
GPHLGPHH_00603 3.1e-31
GPHLGPHH_00604 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPHLGPHH_00605 6.7e-187 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
GPHLGPHH_00606 2.2e-113
GPHLGPHH_00607 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
GPHLGPHH_00608 8.3e-177 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPHLGPHH_00609 7.3e-86 uspA T Belongs to the universal stress protein A family
GPHLGPHH_00610 1.2e-274 pepV 3.5.1.18 E dipeptidase PepV
GPHLGPHH_00611 5.9e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPHLGPHH_00612 2.3e-301 ytgP S Polysaccharide biosynthesis protein
GPHLGPHH_00613 2.9e-41
GPHLGPHH_00614 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPHLGPHH_00615 4.3e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPHLGPHH_00616 6.7e-93 tag 3.2.2.20 L glycosylase
GPHLGPHH_00617 7.9e-258 EGP Major facilitator Superfamily
GPHLGPHH_00618 2.8e-84 perR P Belongs to the Fur family
GPHLGPHH_00619 8.2e-233 cycA E Amino acid permease
GPHLGPHH_00620 4.5e-100 V VanZ like family
GPHLGPHH_00621 1e-23
GPHLGPHH_00622 3.2e-181 L Transposase DDE domain
GPHLGPHH_00623 8.9e-14 M YSIRK type signal peptide
GPHLGPHH_00624 3.2e-181 L Transposase DDE domain
GPHLGPHH_00626 1.3e-140 bamA GM domain, Protein
GPHLGPHH_00627 0.0 tetP J Elongation factor G, domain IV
GPHLGPHH_00628 3.2e-181 L Transposase DDE domain
GPHLGPHH_00629 1.7e-149 yrfB C NADH flavin oxidoreductases, Old Yellow Enzyme family
GPHLGPHH_00630 5.6e-89 P Putative esterase
GPHLGPHH_00631 8.6e-98 I acetylesterase activity
GPHLGPHH_00632 1.2e-47 fldA C Flavodoxin
GPHLGPHH_00633 7.1e-84 P esterase
GPHLGPHH_00635 7.1e-59 C Flavodoxin
GPHLGPHH_00636 2.2e-29 P FAD-binding domain
GPHLGPHH_00637 4.3e-16 P FAD-binding domain
GPHLGPHH_00638 1.3e-32 P FAD-binding domain
GPHLGPHH_00639 1e-71 darA C Flavodoxin
GPHLGPHH_00640 1.2e-79 C Flavodoxin
GPHLGPHH_00641 1.9e-53 K Transcriptional regulator
GPHLGPHH_00642 1e-69 adhR K helix_turn_helix, mercury resistance
GPHLGPHH_00643 4.6e-191 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
GPHLGPHH_00644 7.3e-146 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPHLGPHH_00645 6.2e-122 S Alpha/beta hydrolase of unknown function (DUF915)
GPHLGPHH_00648 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPHLGPHH_00649 1.2e-163 lacX 5.1.3.3 G Aldose 1-epimerase
GPHLGPHH_00650 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GPHLGPHH_00651 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPHLGPHH_00652 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPHLGPHH_00653 8.1e-79 F NUDIX domain
GPHLGPHH_00654 8.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
GPHLGPHH_00655 4.9e-25 yqkB S Belongs to the HesB IscA family
GPHLGPHH_00656 5.6e-26
GPHLGPHH_00658 6.1e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
GPHLGPHH_00659 3.7e-61 asp S Asp23 family, cell envelope-related function
GPHLGPHH_00660 2.8e-25
GPHLGPHH_00661 6.7e-93
GPHLGPHH_00662 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GPHLGPHH_00663 3.5e-180 K Transcriptional regulator, LacI family
GPHLGPHH_00664 1.2e-231 gntT EG Gluconate
GPHLGPHH_00665 9.5e-294 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GPHLGPHH_00666 2.9e-96 K Acetyltransferase (GNAT) domain
GPHLGPHH_00667 3.3e-236 L Transposase
GPHLGPHH_00668 3.2e-181 L Transposase DDE domain
GPHLGPHH_00669 6.1e-42 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GPHLGPHH_00670 1.6e-32 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GPHLGPHH_00671 9.6e-95 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GPHLGPHH_00672 2.2e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPHLGPHH_00673 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
GPHLGPHH_00674 1.8e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPHLGPHH_00675 1e-21 S Protein of unknown function (DUF3042)
GPHLGPHH_00676 3.4e-67 yqhL P Rhodanese-like protein
GPHLGPHH_00677 5.6e-183 glk 2.7.1.2 G Glucokinase
GPHLGPHH_00678 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
GPHLGPHH_00679 1.6e-19 gluP 3.4.21.105 S Peptidase, S54 family
GPHLGPHH_00680 1.6e-74 gluP 3.4.21.105 S Peptidase, S54 family
GPHLGPHH_00681 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPHLGPHH_00682 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPHLGPHH_00683 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
GPHLGPHH_00684 0.0 S membrane
GPHLGPHH_00685 3.1e-68 yneR S Belongs to the HesB IscA family
GPHLGPHH_00686 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPHLGPHH_00687 8e-117 udk 2.7.1.48 F Cytidine monophosphokinase
GPHLGPHH_00688 1.4e-113 rlpA M PFAM NLP P60 protein
GPHLGPHH_00689 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPHLGPHH_00690 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPHLGPHH_00691 4.4e-58 yodB K Transcriptional regulator, HxlR family
GPHLGPHH_00692 1.2e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPHLGPHH_00693 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPHLGPHH_00694 1.6e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GPHLGPHH_00695 1.3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPHLGPHH_00696 5.6e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GPHLGPHH_00697 4.3e-234 V MatE
GPHLGPHH_00698 1.4e-265 yjeM E Amino Acid
GPHLGPHH_00699 3.7e-279 arlS 2.7.13.3 T Histidine kinase
GPHLGPHH_00700 1.5e-121 K response regulator
GPHLGPHH_00701 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GPHLGPHH_00702 2.9e-99 yceD S Uncharacterized ACR, COG1399
GPHLGPHH_00703 3.4e-208 ylbM S Belongs to the UPF0348 family
GPHLGPHH_00704 1.1e-135 yqeM Q Methyltransferase
GPHLGPHH_00705 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GPHLGPHH_00706 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
GPHLGPHH_00707 6.9e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPHLGPHH_00708 1.9e-47 yhbY J RNA-binding protein
GPHLGPHH_00709 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
GPHLGPHH_00710 1.4e-95 yqeG S HAD phosphatase, family IIIA
GPHLGPHH_00711 4.1e-159 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPHLGPHH_00712 8.7e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GPHLGPHH_00713 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GPHLGPHH_00714 2e-158 htpX O Belongs to the peptidase M48B family
GPHLGPHH_00715 7e-93 lemA S LemA family
GPHLGPHH_00716 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPHLGPHH_00717 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
GPHLGPHH_00718 4.9e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
GPHLGPHH_00719 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPHLGPHH_00720 4.7e-159 3.2.1.55 GH51 G Right handed beta helix region
GPHLGPHH_00721 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GPHLGPHH_00722 7.3e-116 srtA 3.4.22.70 M sortase family
GPHLGPHH_00723 4.5e-163 S Alpha/beta hydrolase of unknown function (DUF915)
GPHLGPHH_00724 1.7e-235 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPHLGPHH_00725 4.6e-41 rpmE2 J Ribosomal protein L31
GPHLGPHH_00726 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPHLGPHH_00727 4.4e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GPHLGPHH_00728 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GPHLGPHH_00729 1.3e-67 ywiB S Domain of unknown function (DUF1934)
GPHLGPHH_00730 0.0 2.7.7.6 M Peptidase family M23
GPHLGPHH_00731 6.8e-62 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPHLGPHH_00732 2e-33
GPHLGPHH_00733 1.4e-84 D nuclear chromosome segregation
GPHLGPHH_00734 1.2e-13 S AAA ATPase domain
GPHLGPHH_00735 1.8e-38 S Psort location Cytoplasmic, score 8.96
GPHLGPHH_00736 1.7e-14
GPHLGPHH_00737 7.1e-85 L Helix-turn-helix domain
GPHLGPHH_00738 9.9e-132 O Bacterial dnaA protein
GPHLGPHH_00739 4e-09 3.2.1.18 GH33 M Rib/alpha-like repeat
GPHLGPHH_00741 9.9e-132 O Bacterial dnaA protein
GPHLGPHH_00747 1.1e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GPHLGPHH_00748 1.5e-275 lysP E amino acid
GPHLGPHH_00749 6.6e-09 2.3.1.128 J Acetyltransferase (GNAT) domain
GPHLGPHH_00750 4.4e-118 lssY 3.6.1.27 I phosphatase
GPHLGPHH_00751 1e-81 S Threonine/Serine exporter, ThrE
GPHLGPHH_00752 2e-127 thrE S Putative threonine/serine exporter
GPHLGPHH_00753 1e-30 cspC K Cold shock protein
GPHLGPHH_00754 1.6e-123 sirR K iron dependent repressor
GPHLGPHH_00755 5.5e-164 czcD P cation diffusion facilitator family transporter
GPHLGPHH_00756 2.5e-116 S membrane
GPHLGPHH_00757 8.4e-109 S VIT family
GPHLGPHH_00758 5.5e-83 usp1 T Belongs to the universal stress protein A family
GPHLGPHH_00759 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPHLGPHH_00760 7.5e-152 glnH ET ABC transporter
GPHLGPHH_00761 2.4e-110 gluC P ABC transporter permease
GPHLGPHH_00762 1e-108 glnP P ABC transporter permease
GPHLGPHH_00763 8.3e-221 S CAAX protease self-immunity
GPHLGPHH_00764 3.3e-236 L Transposase
GPHLGPHH_00765 9.9e-132 O Bacterial dnaA protein
GPHLGPHH_00766 9.9e-228 S C4-dicarboxylate anaerobic carrier
GPHLGPHH_00767 1.4e-246 nhaC C Na H antiporter NhaC
GPHLGPHH_00768 4.7e-241 pbuX F xanthine permease
GPHLGPHH_00769 1.2e-279 pipD E Dipeptidase
GPHLGPHH_00770 2.8e-168 corA P CorA-like Mg2+ transporter protein
GPHLGPHH_00771 1.8e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPHLGPHH_00772 6.6e-131 terC P membrane
GPHLGPHH_00773 1.5e-55 trxA O Belongs to the thioredoxin family
GPHLGPHH_00774 1.6e-236 mepA V MATE efflux family protein
GPHLGPHH_00775 3.4e-55 K Transcriptional regulator, ArsR family
GPHLGPHH_00776 1.7e-94 P Cadmium resistance transporter
GPHLGPHH_00777 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
GPHLGPHH_00778 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
GPHLGPHH_00779 4.1e-181 ABC-SBP S ABC transporter
GPHLGPHH_00780 1.7e-73 M PFAM NLP P60 protein
GPHLGPHH_00782 1.2e-101 S Protein of unknown function (DUF3278)
GPHLGPHH_00783 1e-28 WQ51_00220 K Helix-turn-helix domain
GPHLGPHH_00784 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GPHLGPHH_00785 5.5e-45 yitW S Pfam:DUF59
GPHLGPHH_00786 4.7e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPHLGPHH_00787 0.0 tetP J Elongation factor G, domain IV
GPHLGPHH_00788 3.7e-90 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
GPHLGPHH_00790 1.4e-12 S Helix-turn-helix domain
GPHLGPHH_00791 7.8e-127
GPHLGPHH_00794 6.9e-19 S Excisionase from transposon Tn916
GPHLGPHH_00795 2.6e-169 L Belongs to the 'phage' integrase family
GPHLGPHH_00796 2.5e-84
GPHLGPHH_00797 0.0 tetP J Elongation factor G, domain IV
GPHLGPHH_00798 2.6e-21 K Cro/C1-type HTH DNA-binding domain
GPHLGPHH_00799 1.4e-154 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPHLGPHH_00800 7.2e-262 LV site-specific DNA-methyltransferase (adenine-specific) activity
GPHLGPHH_00801 3.2e-181 L Transposase DDE domain
GPHLGPHH_00802 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPHLGPHH_00803 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPHLGPHH_00804 2.7e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GPHLGPHH_00805 5.7e-228 clcA_2 P Chloride transporter, ClC family
GPHLGPHH_00806 4.4e-129 L PFAM transposase IS116 IS110 IS902
GPHLGPHH_00807 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
GPHLGPHH_00808 9.3e-110 lssY 3.6.1.27 I Acid phosphatase homologues
GPHLGPHH_00809 8.7e-41 L Transposase IS66 family
GPHLGPHH_00810 6.4e-90 L Transposase IS66 family
GPHLGPHH_00811 4.3e-13
GPHLGPHH_00812 3e-207 cytX U Belongs to the purine-cytosine permease (2.A.39) family
GPHLGPHH_00813 1.4e-97 ltrA S Bacterial low temperature requirement A protein (LtrA)
GPHLGPHH_00814 6.9e-95 wecD3 K PFAM GCN5-related N-acetyltransferase
GPHLGPHH_00815 1.4e-78
GPHLGPHH_00816 7.9e-122 M Lysin motif
GPHLGPHH_00817 1.8e-196 EGP Major facilitator Superfamily
GPHLGPHH_00818 1e-37 D Antitoxin component of a toxin-antitoxin (TA) module
GPHLGPHH_00819 4.6e-49 S ParE toxin of type II toxin-antitoxin system, parDE
GPHLGPHH_00820 7.6e-95 ywlG S Belongs to the UPF0340 family
GPHLGPHH_00821 2.1e-160 spoU 2.1.1.185 J Methyltransferase
GPHLGPHH_00822 1.3e-224 oxlT P Major Facilitator Superfamily
GPHLGPHH_00823 7.8e-156 2.1.1.72 V Type II restriction enzyme, methylase subunits
GPHLGPHH_00824 2.5e-258 G Major Facilitator Superfamily
GPHLGPHH_00825 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GPHLGPHH_00826 8e-164 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPHLGPHH_00827 3.8e-182 pbuG S permease
GPHLGPHH_00828 6.3e-257 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GPHLGPHH_00829 4.1e-77 L Helix-turn-helix domain
GPHLGPHH_00830 0.0 lacS G Transporter
GPHLGPHH_00831 2.3e-28
GPHLGPHH_00832 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPHLGPHH_00833 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPHLGPHH_00834 4.4e-190 yeaN P Transporter, major facilitator family protein
GPHLGPHH_00835 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
GPHLGPHH_00836 2.7e-82 nrdI F Belongs to the NrdI family
GPHLGPHH_00837 1.6e-236 yhdP S Transporter associated domain
GPHLGPHH_00838 1.1e-153 ypdB V (ABC) transporter
GPHLGPHH_00839 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
GPHLGPHH_00840 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
GPHLGPHH_00841 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
GPHLGPHH_00842 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
GPHLGPHH_00843 2.6e-160 S AI-2E family transporter
GPHLGPHH_00844 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
GPHLGPHH_00845 2.2e-160
GPHLGPHH_00846 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GPHLGPHH_00847 3.6e-138 eutJ E Hsp70 protein
GPHLGPHH_00848 8.3e-159 K helix_turn_helix, arabinose operon control protein
GPHLGPHH_00849 1.6e-37 pduA_4 CQ BMC
GPHLGPHH_00850 2.7e-134 pduB E BMC
GPHLGPHH_00851 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
GPHLGPHH_00852 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
GPHLGPHH_00853 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
GPHLGPHH_00854 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
GPHLGPHH_00855 4.5e-45 pduH S Dehydratase medium subunit
GPHLGPHH_00856 1.8e-56 pduK CQ BMC
GPHLGPHH_00857 7.8e-40 pduA_4 CQ BMC
GPHLGPHH_00858 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
GPHLGPHH_00859 1.3e-79 S Putative propanediol utilisation
GPHLGPHH_00860 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
GPHLGPHH_00861 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
GPHLGPHH_00862 4.5e-77 pduO S Haem-degrading
GPHLGPHH_00863 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
GPHLGPHH_00864 4.3e-203 pduQ C Iron-containing alcohol dehydrogenase
GPHLGPHH_00865 3.8e-218 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPHLGPHH_00866 3e-54 pduU E BMC
GPHLGPHH_00867 4.4e-117 3.1.3.48 T Pfam:Y_phosphatase3C
GPHLGPHH_00868 3.3e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
GPHLGPHH_00869 5.9e-68 P Cadmium resistance transporter
GPHLGPHH_00870 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
GPHLGPHH_00871 2.9e-73 fld C Flavodoxin
GPHLGPHH_00872 7.9e-117 XK27_04590 S NADPH-dependent FMN reductase
GPHLGPHH_00873 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
GPHLGPHH_00874 1.8e-169 cobD 4.1.1.81 E Aminotransferase class I and II
GPHLGPHH_00875 8.1e-204 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
GPHLGPHH_00876 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GPHLGPHH_00877 2.5e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
GPHLGPHH_00878 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GPHLGPHH_00879 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GPHLGPHH_00880 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
GPHLGPHH_00881 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GPHLGPHH_00882 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
GPHLGPHH_00883 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GPHLGPHH_00884 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
GPHLGPHH_00885 2.7e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GPHLGPHH_00886 1.8e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
GPHLGPHH_00887 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GPHLGPHH_00888 8.5e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GPHLGPHH_00889 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GPHLGPHH_00890 6.8e-103 cbiQ P Cobalt transport protein
GPHLGPHH_00891 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
GPHLGPHH_00892 6.6e-239 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
GPHLGPHH_00893 2.7e-58 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
GPHLGPHH_00894 5.4e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPHLGPHH_00895 1.1e-135 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GPHLGPHH_00896 6.2e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
GPHLGPHH_00897 4.3e-239 hemL 5.4.3.8 H Aminotransferase class-III
GPHLGPHH_00898 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
GPHLGPHH_00899 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPHLGPHH_00900 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
GPHLGPHH_00901 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GPHLGPHH_00902 1.6e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
GPHLGPHH_00903 1.2e-54 cnrT EG PFAM EamA-like transporter family
GPHLGPHH_00904 1.3e-50 S Domain of unknown function (DUF4430)
GPHLGPHH_00905 1.1e-71 S ECF transporter, substrate-specific component
GPHLGPHH_00906 9.3e-185 L transposase, IS605 OrfB family
GPHLGPHH_00907 5.5e-51 L Transposase IS200 like
GPHLGPHH_00908 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPHLGPHH_00909 1.2e-168 T Calcineurin-like phosphoesterase superfamily domain
GPHLGPHH_00910 7e-223 mdtG EGP Major facilitator Superfamily
GPHLGPHH_00911 5.7e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GPHLGPHH_00912 4.7e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
GPHLGPHH_00913 3.7e-142 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
GPHLGPHH_00914 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
GPHLGPHH_00915 3.2e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPHLGPHH_00916 0.0 lacZ 3.2.1.23 G -beta-galactosidase
GPHLGPHH_00917 0.0 lacS G Transporter
GPHLGPHH_00918 2.6e-186 lacR K Transcriptional regulator
GPHLGPHH_00919 2.3e-50 S CRISPR-associated protein (Cas_Csn2)
GPHLGPHH_00920 1.3e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GPHLGPHH_00921 7.5e-113 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GPHLGPHH_00922 1.6e-30 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GPHLGPHH_00924 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_00925 6.7e-191 L Transposase IS66 family
GPHLGPHH_00926 2.9e-74 L An automated process has identified a potential problem with this gene model
GPHLGPHH_00927 9.3e-185 L transposase, IS605 OrfB family
GPHLGPHH_00928 1.1e-51 L Transposase IS200 like
GPHLGPHH_00929 4.4e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
GPHLGPHH_00930 0.0 G Peptidase_C39 like family
GPHLGPHH_00931 6.1e-25
GPHLGPHH_00932 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
GPHLGPHH_00933 3.2e-211 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
GPHLGPHH_00934 4.7e-76 M transferase activity, transferring glycosyl groups
GPHLGPHH_00935 3.1e-90 cps3F
GPHLGPHH_00936 3.9e-28 M biosynthesis protein
GPHLGPHH_00937 3.4e-76 rgpB GT2 M Glycosyl transferase family 2
GPHLGPHH_00938 1.8e-67 S Glycosyltransferase like family
GPHLGPHH_00939 1.3e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
GPHLGPHH_00940 2e-72 S Acyltransferase family
GPHLGPHH_00941 5.8e-83
GPHLGPHH_00942 1.2e-145 rfbJ M Glycosyl transferase family 2
GPHLGPHH_00943 1.8e-134
GPHLGPHH_00944 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPHLGPHH_00945 9.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPHLGPHH_00946 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GPHLGPHH_00947 2.7e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPHLGPHH_00948 2.7e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPHLGPHH_00949 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GPHLGPHH_00950 2.7e-160 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPHLGPHH_00951 7.9e-97 rfbX S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPHLGPHH_00952 1.7e-43
GPHLGPHH_00953 8.5e-38 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPHLGPHH_00954 4.7e-38 GT2 M Glycosyl transferase family 2
GPHLGPHH_00955 2.7e-96 wbbK M transferase activity, transferring glycosyl groups
GPHLGPHH_00956 4.3e-44 S Hexapeptide repeat of succinyl-transferase
GPHLGPHH_00957 4e-41 wbbL J Glycosyltransferase group 2 family protein
GPHLGPHH_00958 4.1e-49 capM M Bacterial sugar transferase
GPHLGPHH_00960 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_00961 6.7e-191 L Transposase IS66 family
GPHLGPHH_00962 2.9e-74 L An automated process has identified a potential problem with this gene model
GPHLGPHH_00963 2.7e-127 tesE Q hydratase
GPHLGPHH_00964 2e-116 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPHLGPHH_00966 1.9e-98 L Helix-turn-helix domain
GPHLGPHH_00967 1.5e-159 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPHLGPHH_00968 7.8e-29 L Integrase
GPHLGPHH_00969 1.1e-56 L Lactococcus lactis RepB C-terminus
GPHLGPHH_00970 1.1e-19 S Lysin motif
GPHLGPHH_00971 1.5e-101 L Replication initiation factor
GPHLGPHH_00972 3.4e-36 L Single-strand binding protein family
GPHLGPHH_00973 2.6e-83 L Phage integrase, N-terminal SAM-like domain
GPHLGPHH_00974 1.8e-10
GPHLGPHH_00977 2.2e-65 S Initiator Replication protein
GPHLGPHH_00978 1.5e-10 S HTH domain
GPHLGPHH_00979 4.6e-11 LV site-specific DNA-methyltransferase (adenine-specific) activity
GPHLGPHH_00980 3.7e-31 S Protein of unknown function (DUF2089)
GPHLGPHH_00981 9.3e-28
GPHLGPHH_00983 3.6e-92 L Integrase
GPHLGPHH_00985 3.4e-22 arbx M family 8
GPHLGPHH_00986 4.7e-190 secY2 U SecY translocase
GPHLGPHH_00987 5.9e-259 asp1 S Accessory Sec system protein Asp1
GPHLGPHH_00988 9.8e-257 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
GPHLGPHH_00989 4.4e-17 asp3 S Accessory Sec secretory system ASP3
GPHLGPHH_00990 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPHLGPHH_00992 8.2e-282 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GPHLGPHH_00993 1.6e-260 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GPHLGPHH_00994 1.2e-136 L hmm pf00665
GPHLGPHH_00995 1.5e-71 L Helix-turn-helix domain
GPHLGPHH_00996 7e-12 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
GPHLGPHH_00997 3.6e-08 L Resolvase, N terminal domain
GPHLGPHH_00998 9.3e-77 L Resolvase, N terminal domain
GPHLGPHH_00999 2.9e-33 S FRG
GPHLGPHH_01000 3.7e-21 K Cro/C1-type HTH DNA-binding domain
GPHLGPHH_01001 0.0 tetP J Elongation factor G, domain IV
GPHLGPHH_01002 1.8e-87 tra L Transposase and inactivated derivatives, IS30 family
GPHLGPHH_01003 2e-84 L Belongs to the 'phage' integrase family
GPHLGPHH_01005 2.8e-08
GPHLGPHH_01006 2.1e-58 L Resolvase, N terminal domain
GPHLGPHH_01007 1.2e-10 L Resolvase, N terminal domain
GPHLGPHH_01008 2e-11 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
GPHLGPHH_01012 2.9e-74 L An automated process has identified a potential problem with this gene model
GPHLGPHH_01013 6.7e-191 L Transposase IS66 family
GPHLGPHH_01014 3.4e-53 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_01016 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPHLGPHH_01017 1.5e-165
GPHLGPHH_01018 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPHLGPHH_01019 1.1e-242 purD 6.3.4.13 F Belongs to the GARS family
GPHLGPHH_01020 1.7e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GPHLGPHH_01021 8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPHLGPHH_01022 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GPHLGPHH_01023 2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPHLGPHH_01024 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPHLGPHH_01025 1.4e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPHLGPHH_01026 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPHLGPHH_01027 1.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GPHLGPHH_01028 1.3e-251 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPHLGPHH_01029 5.1e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPHLGPHH_01030 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPHLGPHH_01031 1.1e-100 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GPHLGPHH_01032 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GPHLGPHH_01033 7e-185 thrC 4.2.3.1 E Threonine synthase
GPHLGPHH_01034 3.5e-24 K helix_turn_helix, arabinose operon control protein
GPHLGPHH_01035 2.9e-19 mocA S Oxidoreductase
GPHLGPHH_01036 3.8e-128 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
GPHLGPHH_01037 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GPHLGPHH_01038 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GPHLGPHH_01039 6.6e-174 K AI-2E family transporter
GPHLGPHH_01040 1.8e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
GPHLGPHH_01041 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPHLGPHH_01042 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
GPHLGPHH_01043 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPHLGPHH_01044 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GPHLGPHH_01045 2.1e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GPHLGPHH_01046 1.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GPHLGPHH_01047 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GPHLGPHH_01048 6.6e-124 K LysR substrate binding domain
GPHLGPHH_01049 1.6e-52 azlD S branched-chain amino acid
GPHLGPHH_01050 2.3e-138 azlC E AzlC protein
GPHLGPHH_01051 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
GPHLGPHH_01052 3.8e-125 K response regulator
GPHLGPHH_01053 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPHLGPHH_01054 1.2e-169 deoR K sugar-binding domain protein
GPHLGPHH_01055 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
GPHLGPHH_01056 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
GPHLGPHH_01057 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPHLGPHH_01058 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPHLGPHH_01059 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
GPHLGPHH_01060 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GPHLGPHH_01061 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
GPHLGPHH_01062 1.9e-153 spo0J K Belongs to the ParB family
GPHLGPHH_01063 3.6e-140 soj D Sporulation initiation inhibitor
GPHLGPHH_01064 8.7e-144 noc K Belongs to the ParB family
GPHLGPHH_01065 9.2e-122 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GPHLGPHH_01066 1e-159 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
GPHLGPHH_01067 3.3e-169 rihC 3.2.2.1 F Nucleoside
GPHLGPHH_01068 1.3e-218 nupG F Nucleoside transporter
GPHLGPHH_01069 2.1e-220 cycA E Amino acid permease
GPHLGPHH_01070 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPHLGPHH_01071 2e-264 glnP P ABC transporter
GPHLGPHH_01072 1.9e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPHLGPHH_01073 5.3e-36 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPHLGPHH_01075 1.5e-26 L PFAM transposase IS200-family protein
GPHLGPHH_01076 6.4e-90 L Transposase IS66 family
GPHLGPHH_01077 5.3e-40 L Transposase IS66 family
GPHLGPHH_01080 1.3e-263 dtpT U amino acid peptide transporter
GPHLGPHH_01081 2.7e-149 yjjH S Calcineurin-like phosphoesterase
GPHLGPHH_01084 1e-111
GPHLGPHH_01085 3.2e-248 EGP Major facilitator Superfamily
GPHLGPHH_01086 5.6e-300 aspT P Predicted Permease Membrane Region
GPHLGPHH_01087 2.4e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GPHLGPHH_01088 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
GPHLGPHH_01089 6.9e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPHLGPHH_01090 4.4e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GPHLGPHH_01091 0.0 yhgF K Tex-like protein N-terminal domain protein
GPHLGPHH_01092 1.5e-82 ydcK S Belongs to the SprT family
GPHLGPHH_01094 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
GPHLGPHH_01095 1.1e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
GPHLGPHH_01096 0.0 S Bacterial membrane protein, YfhO
GPHLGPHH_01097 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPHLGPHH_01098 3.8e-167 I alpha/beta hydrolase fold
GPHLGPHH_01099 2.9e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPHLGPHH_01100 1.1e-119 tcyB E ABC transporter
GPHLGPHH_01101 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPHLGPHH_01102 4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GPHLGPHH_01103 6.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
GPHLGPHH_01104 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPHLGPHH_01105 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
GPHLGPHH_01106 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GPHLGPHH_01107 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPHLGPHH_01108 1.1e-204 yacL S domain protein
GPHLGPHH_01109 1.3e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPHLGPHH_01110 4.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPHLGPHH_01111 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPHLGPHH_01112 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPHLGPHH_01113 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GPHLGPHH_01114 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
GPHLGPHH_01115 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPHLGPHH_01116 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GPHLGPHH_01117 2.8e-224 aadAT EK Aminotransferase, class I
GPHLGPHH_01119 1.8e-32 M Glycosyl transferase family group 2
GPHLGPHH_01120 6.3e-154 M Glycosyl transferase family group 2
GPHLGPHH_01121 4e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPHLGPHH_01122 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPHLGPHH_01123 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GPHLGPHH_01124 5.7e-35
GPHLGPHH_01125 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GPHLGPHH_01126 2.4e-56 K transcriptional regulator PadR family
GPHLGPHH_01127 8.7e-81 XK27_06920 S Protein of unknown function (DUF1700)
GPHLGPHH_01128 1.6e-132 S Putative adhesin
GPHLGPHH_01129 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GPHLGPHH_01130 8.5e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPHLGPHH_01131 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPHLGPHH_01132 3.4e-35 nrdH O Glutaredoxin
GPHLGPHH_01133 5.2e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GPHLGPHH_01134 7.6e-290 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPHLGPHH_01135 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPHLGPHH_01136 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPHLGPHH_01137 1.1e-37 S Protein of unknown function (DUF2508)
GPHLGPHH_01138 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPHLGPHH_01139 2.9e-51 yaaQ S Cyclic-di-AMP receptor
GPHLGPHH_01140 1.7e-182 holB 2.7.7.7 L DNA polymerase III
GPHLGPHH_01141 3.1e-43 yabA L Involved in initiation control of chromosome replication
GPHLGPHH_01142 7.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPHLGPHH_01143 8.4e-134 fat 3.1.2.21 I Acyl-ACP thioesterase
GPHLGPHH_01144 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GPHLGPHH_01145 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPHLGPHH_01146 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GPHLGPHH_01147 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPHLGPHH_01148 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
GPHLGPHH_01149 2e-100 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
GPHLGPHH_01150 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPHLGPHH_01151 2e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPHLGPHH_01152 2e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPHLGPHH_01153 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPHLGPHH_01154 5.6e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
GPHLGPHH_01155 5.9e-227 mtnE 2.6.1.83 E Aminotransferase
GPHLGPHH_01156 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPHLGPHH_01157 0.0 uup S ABC transporter, ATP-binding protein
GPHLGPHH_01158 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GPHLGPHH_01160 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPHLGPHH_01161 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GPHLGPHH_01162 7.6e-80 S Aminoacyl-tRNA editing domain
GPHLGPHH_01163 4.5e-302 ybeC E amino acid
GPHLGPHH_01164 0.0 ydaO E amino acid
GPHLGPHH_01165 2.7e-39
GPHLGPHH_01166 2e-57 ltrA S Bacterial low temperature requirement A protein (LtrA)
GPHLGPHH_01167 1.2e-42 ltrA S Bacterial low temperature requirement A protein (LtrA)
GPHLGPHH_01168 1.6e-79 uspA T universal stress protein
GPHLGPHH_01169 1.4e-78 K AsnC family
GPHLGPHH_01170 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPHLGPHH_01171 6.3e-103 dedA 3.1.3.1 S SNARE associated Golgi protein
GPHLGPHH_01172 2e-09 IQ KR domain
GPHLGPHH_01173 6.2e-114 IQ KR domain
GPHLGPHH_01174 3.3e-133 S membrane transporter protein
GPHLGPHH_01175 7.9e-97 S ABC-type cobalt transport system, permease component
GPHLGPHH_01176 3.8e-249 cbiO1 S ABC transporter, ATP-binding protein
GPHLGPHH_01177 6.6e-111 P Cobalt transport protein
GPHLGPHH_01178 1.6e-52 yvlA
GPHLGPHH_01179 0.0 yjcE P Sodium proton antiporter
GPHLGPHH_01180 6.4e-52 ypaA S Protein of unknown function (DUF1304)
GPHLGPHH_01181 1.7e-187 D Alpha beta
GPHLGPHH_01182 1e-72 K Transcriptional regulator
GPHLGPHH_01183 3.2e-158
GPHLGPHH_01184 1.1e-175 1.6.5.5 C Zinc-binding dehydrogenase
GPHLGPHH_01185 2.7e-255 G PTS system Galactitol-specific IIC component
GPHLGPHH_01186 7.6e-211 EGP Major facilitator Superfamily
GPHLGPHH_01187 4.4e-134 V ABC transporter
GPHLGPHH_01188 9e-106
GPHLGPHH_01189 8.9e-14
GPHLGPHH_01190 7.1e-63
GPHLGPHH_01191 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
GPHLGPHH_01192 6.6e-81 uspA T universal stress protein
GPHLGPHH_01193 0.0 tetP J elongation factor G
GPHLGPHH_01194 2.9e-165 GK ROK family
GPHLGPHH_01195 7.2e-237 brnQ U Component of the transport system for branched-chain amino acids
GPHLGPHH_01196 4.2e-138 aroD S Serine hydrolase (FSH1)
GPHLGPHH_01197 4.6e-80 yagE E amino acid
GPHLGPHH_01198 2.1e-116 yagE E amino acid
GPHLGPHH_01199 2.4e-17 yagE E amino acid
GPHLGPHH_01200 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GPHLGPHH_01201 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
GPHLGPHH_01202 1.8e-84 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPHLGPHH_01203 2.6e-269 pipD E Dipeptidase
GPHLGPHH_01204 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
GPHLGPHH_01205 0.0 yfiC V ABC transporter
GPHLGPHH_01206 1.8e-288 lmrA V ABC transporter, ATP-binding protein
GPHLGPHH_01207 1.3e-17 K Winged helix DNA-binding domain
GPHLGPHH_01208 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPHLGPHH_01209 2.9e-19 S PFAM Archaeal ATPase
GPHLGPHH_01210 1.2e-16 sprD D Domain of Unknown Function (DUF1542)
GPHLGPHH_01211 3e-46 L Transposase IS66 family
GPHLGPHH_01212 5.5e-37 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPHLGPHH_01213 1.2e-50 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPHLGPHH_01214 4e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPHLGPHH_01215 7.3e-116 ybhL S Belongs to the BI1 family
GPHLGPHH_01216 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
GPHLGPHH_01217 3e-195 S Protein of unknown function (DUF3114)
GPHLGPHH_01218 2.2e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GPHLGPHH_01219 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPHLGPHH_01220 1.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
GPHLGPHH_01221 9.1e-62 S Domain of unknown function (DUF4828)
GPHLGPHH_01222 5e-190 mocA S Oxidoreductase
GPHLGPHH_01223 1.9e-231 yfmL L DEAD DEAH box helicase
GPHLGPHH_01225 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPHLGPHH_01226 7.1e-56
GPHLGPHH_01227 1.3e-67 gtcA S Teichoic acid glycosylation protein
GPHLGPHH_01228 1.4e-78 fld C Flavodoxin
GPHLGPHH_01229 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
GPHLGPHH_01230 1.6e-221 arcT 2.6.1.1 E Aminotransferase
GPHLGPHH_01231 9.5e-256 E Arginine ornithine antiporter
GPHLGPHH_01232 3.4e-280 yjeM E Amino Acid
GPHLGPHH_01233 1.8e-143 yihY S Belongs to the UPF0761 family
GPHLGPHH_01234 6.6e-34 S Protein of unknown function (DUF2922)
GPHLGPHH_01235 4.9e-31
GPHLGPHH_01236 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
GPHLGPHH_01237 1.9e-146 cps1D M Domain of unknown function (DUF4422)
GPHLGPHH_01238 1e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
GPHLGPHH_01239 2.1e-117 rfbP 2.7.8.6 M Bacterial sugar transferase
GPHLGPHH_01240 2.7e-47 K Transcriptional regulator
GPHLGPHH_01241 1.9e-40 folT S ECF transporter, substrate-specific component
GPHLGPHH_01242 1e-17 folT S ECF transporter, substrate-specific component
GPHLGPHH_01243 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
GPHLGPHH_01244 1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GPHLGPHH_01245 2.6e-121 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
GPHLGPHH_01246 2.2e-194 2.7.7.65 T GGDEF domain
GPHLGPHH_01247 4.7e-77
GPHLGPHH_01248 3.3e-236 L Transposase
GPHLGPHH_01249 1.3e-148 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
GPHLGPHH_01250 1e-270 ywfO S HD domain protein
GPHLGPHH_01251 2.1e-146 yxeH S hydrolase
GPHLGPHH_01252 9e-48
GPHLGPHH_01253 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPHLGPHH_01254 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPHLGPHH_01255 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
GPHLGPHH_01256 8e-127 znuB U ABC 3 transport family
GPHLGPHH_01257 2.2e-122 fhuC P ABC transporter
GPHLGPHH_01258 6.9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
GPHLGPHH_01259 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPHLGPHH_01260 6.8e-37 veg S Biofilm formation stimulator VEG
GPHLGPHH_01261 3.6e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GPHLGPHH_01262 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPHLGPHH_01263 3.5e-154 tatD L hydrolase, TatD family
GPHLGPHH_01264 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPHLGPHH_01265 1.2e-160 yunF F Protein of unknown function DUF72
GPHLGPHH_01267 1.5e-129 cobB K SIR2 family
GPHLGPHH_01268 8.6e-176
GPHLGPHH_01269 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GPHLGPHH_01270 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GPHLGPHH_01271 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPHLGPHH_01272 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
GPHLGPHH_01273 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
GPHLGPHH_01274 0.0 helD 3.6.4.12 L DNA helicase
GPHLGPHH_01275 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GPHLGPHH_01277 7.7e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPHLGPHH_01278 4.4e-264 yfnA E amino acid
GPHLGPHH_01279 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPHLGPHH_01280 8.9e-41 1.3.5.4 S FMN binding
GPHLGPHH_01281 3.7e-221 norA EGP Major facilitator Superfamily
GPHLGPHH_01282 9.9e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPHLGPHH_01283 6.3e-154 metQ1 P Belongs to the nlpA lipoprotein family
GPHLGPHH_01284 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPHLGPHH_01285 4.1e-103 metI P ABC transporter permease
GPHLGPHH_01286 1.2e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GPHLGPHH_01287 3e-188 clcA P chloride
GPHLGPHH_01288 8.8e-215 L transposase, IS605 OrfB family
GPHLGPHH_01289 3.4e-58 L PFAM transposase IS200-family protein
GPHLGPHH_01290 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GPHLGPHH_01291 1.9e-102 proW P ABC transporter, permease protein
GPHLGPHH_01292 6.5e-142 proV E ABC transporter, ATP-binding protein
GPHLGPHH_01293 3.1e-105 proWZ P ABC transporter permease
GPHLGPHH_01294 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
GPHLGPHH_01295 3.8e-73 K Transcriptional regulator
GPHLGPHH_01296 1.6e-35 1.6.5.2 GM NAD(P)H-binding
GPHLGPHH_01298 1.8e-220 5.4.2.7 G Metalloenzyme superfamily
GPHLGPHH_01299 0.0 cadA P P-type ATPase
GPHLGPHH_01300 3.1e-109 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GPHLGPHH_01301 2.3e-125
GPHLGPHH_01302 2.6e-52 S Sugar efflux transporter for intercellular exchange
GPHLGPHH_01303 4.2e-245 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GPHLGPHH_01305 0.0 L Helicase C-terminal domain protein
GPHLGPHH_01306 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
GPHLGPHH_01307 1.6e-177 S Aldo keto reductase
GPHLGPHH_01309 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPHLGPHH_01310 2.9e-27 psiE S Phosphate-starvation-inducible E
GPHLGPHH_01311 4.1e-98 ydeN S Serine hydrolase
GPHLGPHH_01313 1e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPHLGPHH_01314 8.9e-254 nhaC C Na H antiporter NhaC
GPHLGPHH_01315 2.9e-37 S Cytochrome b5-like Heme/Steroid binding domain
GPHLGPHH_01316 1.8e-113 ywnB S NAD(P)H-binding
GPHLGPHH_01317 3.2e-36
GPHLGPHH_01318 7.1e-19 IQ Dehydrogenase reductase
GPHLGPHH_01319 1.9e-59 IQ Dehydrogenase reductase
GPHLGPHH_01320 2e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
GPHLGPHH_01321 5.6e-15 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPHLGPHH_01322 5.9e-20 3.2.1.18 GH33 M Rib/alpha-like repeat
GPHLGPHH_01323 4e-81 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPHLGPHH_01324 2.5e-144 ET Bacterial periplasmic substrate-binding proteins
GPHLGPHH_01325 1.4e-97 arpJ P ABC transporter permease
GPHLGPHH_01326 2.4e-133 3.6.3.21 E ABC transporter, ATP-binding protein
GPHLGPHH_01327 3.1e-125 frlR K UTRA domain
GPHLGPHH_01328 1.7e-151 rbsK 2.7.1.15, 2.7.1.184, 2.7.1.4 G pfkB family carbohydrate kinase
GPHLGPHH_01329 7e-181 glmS2 G Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GPHLGPHH_01331 2.2e-178 L transposase, IS605 OrfB family
GPHLGPHH_01333 2e-116 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPHLGPHH_01334 2.7e-127 tesE Q hydratase
GPHLGPHH_01335 3.3e-236 L Transposase
GPHLGPHH_01336 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPHLGPHH_01337 2.9e-57
GPHLGPHH_01338 3.4e-74 merR K MerR HTH family regulatory protein
GPHLGPHH_01339 7.2e-270 lmrB EGP Major facilitator Superfamily
GPHLGPHH_01340 2.7e-121 S Domain of unknown function (DUF4811)
GPHLGPHH_01341 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GPHLGPHH_01343 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPHLGPHH_01344 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
GPHLGPHH_01345 9.4e-186 I Alpha beta
GPHLGPHH_01346 6.5e-271 emrY EGP Major facilitator Superfamily
GPHLGPHH_01347 4.7e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
GPHLGPHH_01348 9.4e-253 yjjP S Putative threonine/serine exporter
GPHLGPHH_01349 3.9e-159 mleR K LysR family
GPHLGPHH_01350 6.4e-252 yflS P Sodium:sulfate symporter transmembrane region
GPHLGPHH_01351 3.1e-267 frdC 1.3.5.4 C FAD binding domain
GPHLGPHH_01352 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GPHLGPHH_01353 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
GPHLGPHH_01354 4.3e-158 mleR K LysR family
GPHLGPHH_01355 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPHLGPHH_01356 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
GPHLGPHH_01357 1.5e-294 L PFAM plasmid pRiA4b ORF-3 family protein
GPHLGPHH_01358 4.1e-161 L transposase, IS605 OrfB family
GPHLGPHH_01359 1.5e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
GPHLGPHH_01360 6.4e-21
GPHLGPHH_01361 2e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GPHLGPHH_01362 3e-75
GPHLGPHH_01363 8.7e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPHLGPHH_01364 5.3e-131 ponA V Beta-lactamase enzyme family
GPHLGPHH_01365 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
GPHLGPHH_01366 4.8e-216 uhpT EGP Major facilitator Superfamily
GPHLGPHH_01367 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
GPHLGPHH_01368 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
GPHLGPHH_01369 3e-181 yfeX P Peroxidase
GPHLGPHH_01370 4.5e-168 lsa S ABC transporter
GPHLGPHH_01371 5.1e-133 I alpha/beta hydrolase fold
GPHLGPHH_01372 1.8e-179 MA20_14895 S Conserved hypothetical protein 698
GPHLGPHH_01373 5.4e-95 S NADPH-dependent FMN reductase
GPHLGPHH_01374 9.7e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPHLGPHH_01375 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GPHLGPHH_01376 6.3e-230 mntH P H( )-stimulated, divalent metal cation uptake system
GPHLGPHH_01377 2.4e-79 Q Methyltransferase
GPHLGPHH_01378 7.7e-115 ktrA P domain protein
GPHLGPHH_01379 7.6e-239 ktrB P Potassium uptake protein
GPHLGPHH_01380 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
GPHLGPHH_01381 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GPHLGPHH_01382 1.7e-223 G Glycosyl hydrolases family 8
GPHLGPHH_01383 2.5e-242 ydaM M Glycosyl transferase
GPHLGPHH_01385 5.2e-140
GPHLGPHH_01386 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
GPHLGPHH_01387 1.5e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPHLGPHH_01388 2.6e-155 pstA P Phosphate transport system permease protein PstA
GPHLGPHH_01389 9.5e-153 pstC P probably responsible for the translocation of the substrate across the membrane
GPHLGPHH_01390 1.1e-158 pstS P Phosphate
GPHLGPHH_01391 2.4e-130 K Transcriptional regulatory protein, C-terminal domain protein
GPHLGPHH_01392 1.6e-15 K Transcriptional regulator, HxlR family
GPHLGPHH_01393 6.5e-190
GPHLGPHH_01394 1.2e-97 2.3.1.128 K acetyltransferase
GPHLGPHH_01395 6.8e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
GPHLGPHH_01396 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
GPHLGPHH_01397 2.4e-62 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPHLGPHH_01398 3.9e-182
GPHLGPHH_01399 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPHLGPHH_01400 5.8e-184 S Phosphotransferase system, EIIC
GPHLGPHH_01401 3e-18 NU Mycoplasma protein of unknown function, DUF285
GPHLGPHH_01403 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
GPHLGPHH_01404 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GPHLGPHH_01405 4.6e-123 O Zinc-dependent metalloprotease
GPHLGPHH_01406 9.6e-56 L Helix-turn-helix domain
GPHLGPHH_01410 1.4e-159 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPHLGPHH_01411 1e-159 degV S EDD domain protein, DegV family
GPHLGPHH_01412 5.6e-89
GPHLGPHH_01413 1.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPHLGPHH_01414 8.7e-156 gspA M family 8
GPHLGPHH_01415 2.8e-154 S Alpha beta hydrolase
GPHLGPHH_01416 1.5e-94 K Acetyltransferase (GNAT) domain
GPHLGPHH_01417 2.4e-240 XK27_08635 S UPF0210 protein
GPHLGPHH_01418 2.1e-39 gcvR T Belongs to the UPF0237 family
GPHLGPHH_01419 3.6e-168 1.1.1.346 C Aldo keto reductase
GPHLGPHH_01420 5.4e-96 exuR K Periplasmic binding protein domain
GPHLGPHH_01421 7.8e-221 yjmB G MFS/sugar transport protein
GPHLGPHH_01422 9.2e-230 uxaC 5.3.1.12 G glucuronate isomerase
GPHLGPHH_01423 1.8e-98 S module of peptide synthetase
GPHLGPHH_01425 1.7e-151 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
GPHLGPHH_01426 1.8e-124 uxaA 4.2.1.7, 4.4.1.24 G Altronate
GPHLGPHH_01427 7.3e-89 yqhA G Aldose 1-epimerase
GPHLGPHH_01428 3.1e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
GPHLGPHH_01429 3.1e-164 uxaA 4.2.1.7, 4.4.1.24 G Altronate
GPHLGPHH_01430 1.7e-126 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
GPHLGPHH_01431 1.7e-53 kdgR K FCD domain
GPHLGPHH_01432 4.8e-211 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
GPHLGPHH_01433 2.6e-181 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
GPHLGPHH_01434 1.1e-217 uxuT G MFS/sugar transport protein
GPHLGPHH_01435 3.9e-220 uxaC 5.3.1.12 G glucuronate isomerase
GPHLGPHH_01436 2.7e-13 higA K Helix-turn-helix XRE-family like proteins
GPHLGPHH_01437 1.4e-15 higA K Helix-turn-helix XRE-family like proteins
GPHLGPHH_01438 2.6e-46 G Xylose isomerase-like TIM barrel
GPHLGPHH_01439 6.3e-138 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GPHLGPHH_01440 4.6e-130 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPHLGPHH_01441 7.2e-69 K Bacterial transcriptional regulator
GPHLGPHH_01442 5.5e-145 K LysR substrate binding domain protein
GPHLGPHH_01443 2.6e-50 C Flavodoxin
GPHLGPHH_01444 2.2e-75 yphH S Cupin domain
GPHLGPHH_01445 6.7e-70 yeaL S UPF0756 membrane protein
GPHLGPHH_01446 6.5e-233 EGP Major facilitator Superfamily
GPHLGPHH_01447 5.5e-74 copY K Copper transport repressor CopY TcrY
GPHLGPHH_01448 7.2e-245 yhdP S Transporter associated domain
GPHLGPHH_01449 0.0 ubiB S ABC1 family
GPHLGPHH_01450 4.3e-144 S DUF218 domain
GPHLGPHH_01451 4.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPHLGPHH_01452 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPHLGPHH_01453 5e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPHLGPHH_01454 0.0 uvrA3 L excinuclease ABC, A subunit
GPHLGPHH_01463 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GPHLGPHH_01464 2e-135 accA 2.1.3.15, 6.4.1.2 I alpha subunit
GPHLGPHH_01465 4.2e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPHLGPHH_01466 2.4e-256 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
GPHLGPHH_01467 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPHLGPHH_01468 7.6e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GPHLGPHH_01469 4.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPHLGPHH_01470 7.6e-124 IQ reductase
GPHLGPHH_01471 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GPHLGPHH_01472 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPHLGPHH_01473 7.9e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPHLGPHH_01474 1.2e-76 marR K Transcriptional regulator, MarR family
GPHLGPHH_01475 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPHLGPHH_01477 1.3e-201 xerS L Belongs to the 'phage' integrase family
GPHLGPHH_01478 5.8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
GPHLGPHH_01479 1.8e-164 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
GPHLGPHH_01480 1.6e-53 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
GPHLGPHH_01481 3e-156 rssA S Phospholipase, patatin family
GPHLGPHH_01482 9.4e-118 L Integrase
GPHLGPHH_01483 4.1e-99 EG EamA-like transporter family
GPHLGPHH_01484 1.5e-71 L Helix-turn-helix domain
GPHLGPHH_01485 0.0 FbpA K Fibronectin-binding protein
GPHLGPHH_01486 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GPHLGPHH_01487 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
GPHLGPHH_01488 2.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPHLGPHH_01489 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPHLGPHH_01490 5.6e-65 esbA S Family of unknown function (DUF5322)
GPHLGPHH_01491 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
GPHLGPHH_01492 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GPHLGPHH_01493 8.8e-81 F Belongs to the NrdI family
GPHLGPHH_01494 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GPHLGPHH_01495 1.6e-100 ypsA S Belongs to the UPF0398 family
GPHLGPHH_01496 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPHLGPHH_01497 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GPHLGPHH_01498 1.3e-160 EG EamA-like transporter family
GPHLGPHH_01499 8.1e-123 dnaD L DnaD domain protein
GPHLGPHH_01500 9.9e-86 ypmB S Protein conserved in bacteria
GPHLGPHH_01501 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GPHLGPHH_01502 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GPHLGPHH_01503 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GPHLGPHH_01504 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GPHLGPHH_01505 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GPHLGPHH_01506 9.3e-86 S Protein of unknown function (DUF1440)
GPHLGPHH_01507 3.5e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GPHLGPHH_01508 7.8e-289 L Transposase
GPHLGPHH_01509 0.0 rafA 3.2.1.22 G alpha-galactosidase
GPHLGPHH_01510 1.5e-186 galR K Periplasmic binding protein-like domain
GPHLGPHH_01511 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
GPHLGPHH_01512 1.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPHLGPHH_01513 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
GPHLGPHH_01514 4.4e-147 f42a O Band 7 protein
GPHLGPHH_01515 2.7e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GPHLGPHH_01516 1e-153 yitU 3.1.3.104 S hydrolase
GPHLGPHH_01517 9.2e-39 S Cytochrome B5
GPHLGPHH_01518 2.8e-114 nreC K PFAM regulatory protein LuxR
GPHLGPHH_01519 5.2e-159 hipB K Helix-turn-helix
GPHLGPHH_01520 2.8e-57 yitW S Iron-sulfur cluster assembly protein
GPHLGPHH_01521 1.2e-271 sufB O assembly protein SufB
GPHLGPHH_01522 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
GPHLGPHH_01523 4.9e-232 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPHLGPHH_01524 5.1e-240 sufD O FeS assembly protein SufD
GPHLGPHH_01525 1.9e-144 sufC O FeS assembly ATPase SufC
GPHLGPHH_01526 2.4e-30 feoA P FeoA domain
GPHLGPHH_01527 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
GPHLGPHH_01528 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GPHLGPHH_01529 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPHLGPHH_01530 3e-60 ydiI Q Thioesterase superfamily
GPHLGPHH_01531 7.3e-106 yvrI K sigma factor activity
GPHLGPHH_01532 2.9e-197 G Transporter, major facilitator family protein
GPHLGPHH_01533 0.0 S Bacterial membrane protein YfhO
GPHLGPHH_01534 5.5e-41 T Ion transport 2 domain protein
GPHLGPHH_01535 2.6e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GPHLGPHH_01536 1.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GPHLGPHH_01537 3.6e-95 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
GPHLGPHH_01538 1.8e-182 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPHLGPHH_01539 2e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GPHLGPHH_01541 0.0 L PLD-like domain
GPHLGPHH_01542 3.1e-57 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain protein
GPHLGPHH_01543 8.9e-178 L Belongs to the 'phage' integrase family
GPHLGPHH_01544 1.2e-76 3.1.21.3 V Type I restriction modification DNA specificity domain
GPHLGPHH_01545 4.5e-193 hsdM 2.1.1.72 V type I restriction-modification system
GPHLGPHH_01546 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GPHLGPHH_01547 1.3e-14 IQ KR domain
GPHLGPHH_01548 3.5e-36 yhaI S Protein of unknown function (DUF805)
GPHLGPHH_01549 8.5e-44
GPHLGPHH_01550 2.4e-22
GPHLGPHH_01551 4.2e-47
GPHLGPHH_01552 3.3e-236 L Transposase
GPHLGPHH_01553 5.4e-136 glsA 3.5.1.2 E Belongs to the glutaminase family
GPHLGPHH_01554 9.8e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPHLGPHH_01555 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPHLGPHH_01556 2.4e-231 dltB M MBOAT, membrane-bound O-acyltransferase family
GPHLGPHH_01557 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPHLGPHH_01559 1.1e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GPHLGPHH_01560 3.1e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPHLGPHH_01561 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
GPHLGPHH_01562 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
GPHLGPHH_01563 8.9e-242 codA 3.5.4.1 F cytosine deaminase
GPHLGPHH_01564 6.4e-145 tesE Q hydratase
GPHLGPHH_01565 1.1e-113 S (CBS) domain
GPHLGPHH_01566 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GPHLGPHH_01567 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPHLGPHH_01568 2.1e-39 yabO J S4 domain protein
GPHLGPHH_01569 5.6e-56 divIC D Septum formation initiator
GPHLGPHH_01570 9.8e-67 yabR J RNA binding
GPHLGPHH_01571 1.5e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GPHLGPHH_01572 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPHLGPHH_01573 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPHLGPHH_01574 2.6e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPHLGPHH_01575 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPHLGPHH_01576 3.7e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GPHLGPHH_01578 3.3e-236 L Transposase
GPHLGPHH_01579 2.3e-248 pgaC GT2 M Glycosyl transferase
GPHLGPHH_01580 1e-137 T EAL domain
GPHLGPHH_01581 6.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
GPHLGPHH_01582 1.9e-59 yneR
GPHLGPHH_01583 3.6e-101 qorB 1.6.5.2 GM NmrA-like family
GPHLGPHH_01584 1.6e-160 akr5f 1.1.1.346 S reductase
GPHLGPHH_01585 7.6e-147 K Transcriptional regulator
GPHLGPHH_01586 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
GPHLGPHH_01587 2.3e-155 ypuA S Protein of unknown function (DUF1002)
GPHLGPHH_01588 2.4e-228 aadAT EK Aminotransferase, class I
GPHLGPHH_01589 6.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPHLGPHH_01590 6e-154 tesE Q hydratase
GPHLGPHH_01591 5.5e-52 S Alpha beta hydrolase
GPHLGPHH_01592 4.1e-89 XK27_08850 J Aminoacyl-tRNA editing domain
GPHLGPHH_01593 2.1e-70 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPHLGPHH_01594 2.8e-193 V Beta-lactamase
GPHLGPHH_01595 1.7e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPHLGPHH_01596 1.8e-98 yhiD S MgtC family
GPHLGPHH_01597 3.3e-106 S GyrI-like small molecule binding domain
GPHLGPHH_01598 6.3e-265 L PFAM Integrase catalytic region
GPHLGPHH_01599 7.3e-110 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GPHLGPHH_01600 3.2e-50 azlD E Branched-chain amino acid transport
GPHLGPHH_01601 4.1e-119 azlC E azaleucine resistance protein AzlC
GPHLGPHH_01602 1e-257 K Aminotransferase class I and II
GPHLGPHH_01603 3.3e-189 S amidohydrolase
GPHLGPHH_01604 5.5e-105 L hmm pf00665
GPHLGPHH_01605 2.4e-38 L PFAM Integrase catalytic region
GPHLGPHH_01606 5.6e-46 L PFAM Integrase catalytic region
GPHLGPHH_01607 9.2e-49 2.3.1.183 M Acetyltransferase GNAT family
GPHLGPHH_01608 8.6e-15 2.3.1.183 M Acetyltransferase GNAT family
GPHLGPHH_01609 5e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GPHLGPHH_01610 1.1e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
GPHLGPHH_01611 5.8e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPHLGPHH_01612 0.0 asnB 6.3.5.4 E Asparagine synthase
GPHLGPHH_01613 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GPHLGPHH_01614 1.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPHLGPHH_01615 1.1e-130 jag S R3H domain protein
GPHLGPHH_01616 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPHLGPHH_01617 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GPHLGPHH_01618 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GPHLGPHH_01619 1.1e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPHLGPHH_01620 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPHLGPHH_01621 4.9e-34 yaaA S S4 domain protein YaaA
GPHLGPHH_01622 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPHLGPHH_01623 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPHLGPHH_01624 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPHLGPHH_01625 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
GPHLGPHH_01626 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPHLGPHH_01627 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPHLGPHH_01628 1.3e-75 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPHLGPHH_01629 6.5e-18 deoR K sugar-binding domain protein
GPHLGPHH_01630 1.1e-52 deoR K sugar-binding domain protein
GPHLGPHH_01631 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GPHLGPHH_01632 2e-74 rplI J Binds to the 23S rRNA
GPHLGPHH_01633 4.1e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GPHLGPHH_01634 2.6e-206 yttB EGP Major facilitator Superfamily
GPHLGPHH_01635 9.1e-61
GPHLGPHH_01636 1.4e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
GPHLGPHH_01637 3.8e-38 Z012_01130 S Fic/DOC family
GPHLGPHH_01638 1.6e-69 Z012_01130 S Fic/DOC family
GPHLGPHH_01640 1.8e-72 K helix_turn_helix multiple antibiotic resistance protein
GPHLGPHH_01641 2.9e-307 lmrA 3.6.3.44 V ABC transporter
GPHLGPHH_01643 3.1e-130 K response regulator
GPHLGPHH_01644 0.0 vicK 2.7.13.3 T Histidine kinase
GPHLGPHH_01645 2e-244 yycH S YycH protein
GPHLGPHH_01646 7.8e-149 yycI S YycH protein
GPHLGPHH_01647 5.9e-154 vicX 3.1.26.11 S domain protein
GPHLGPHH_01648 6.6e-216 htrA 3.4.21.107 O serine protease
GPHLGPHH_01649 1e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
GPHLGPHH_01650 1.5e-175 ABC-SBP S ABC transporter
GPHLGPHH_01651 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPHLGPHH_01653 2.9e-96 S reductase
GPHLGPHH_01654 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
GPHLGPHH_01655 1.3e-154 glcU U sugar transport
GPHLGPHH_01656 1.9e-149 E Glyoxalase-like domain
GPHLGPHH_01657 3.5e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPHLGPHH_01658 3.7e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
GPHLGPHH_01659 3.1e-142 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPHLGPHH_01660 2.8e-128 V ABC transporter
GPHLGPHH_01661 5.1e-213 bacI V MacB-like periplasmic core domain
GPHLGPHH_01662 1.8e-39
GPHLGPHH_01663 7.6e-258 S Putative peptidoglycan binding domain
GPHLGPHH_01665 1.2e-08 2.7.13.3 T GHKL domain
GPHLGPHH_01666 2.5e-53 L An automated process has identified a potential problem with this gene model
GPHLGPHH_01667 1.1e-84 K FR47-like protein
GPHLGPHH_01668 1.9e-74 osmC O OsmC-like protein
GPHLGPHH_01669 1.6e-172 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPHLGPHH_01670 1.8e-215 patA 2.6.1.1 E Aminotransferase
GPHLGPHH_01671 7.8e-32
GPHLGPHH_01672 0.0 clpL O associated with various cellular activities
GPHLGPHH_01674 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
GPHLGPHH_01675 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPHLGPHH_01676 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GPHLGPHH_01677 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GPHLGPHH_01678 1.5e-172 malR K Transcriptional regulator, LacI family
GPHLGPHH_01679 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
GPHLGPHH_01680 1.1e-256 malT G Major Facilitator
GPHLGPHH_01681 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GPHLGPHH_01682 3.5e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
GPHLGPHH_01683 4e-73
GPHLGPHH_01684 7.4e-88 2.7.6.5 T Region found in RelA / SpoT proteins
GPHLGPHH_01685 3.3e-118 K response regulator
GPHLGPHH_01686 9e-226 sptS 2.7.13.3 T Histidine kinase
GPHLGPHH_01687 5.7e-214 yfeO P Voltage gated chloride channel
GPHLGPHH_01688 3.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GPHLGPHH_01689 1.5e-135 puuD S peptidase C26
GPHLGPHH_01690 2.3e-167 yvgN C Aldo keto reductase
GPHLGPHH_01691 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
GPHLGPHH_01692 3e-87 hmpT S ECF-type riboflavin transporter, S component
GPHLGPHH_01693 1.9e-261 nox C NADH oxidase
GPHLGPHH_01694 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPHLGPHH_01695 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPHLGPHH_01696 1.1e-83
GPHLGPHH_01697 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GPHLGPHH_01699 1.1e-13 steT_1 E amino acid
GPHLGPHH_01700 2.1e-12 K Transcriptional regulator, TetR family
GPHLGPHH_01701 4.8e-76 K Transcriptional regulator, TetR family
GPHLGPHH_01702 2.2e-72
GPHLGPHH_01703 1.1e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
GPHLGPHH_01704 4.5e-272 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
GPHLGPHH_01705 1.5e-279 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
GPHLGPHH_01706 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
GPHLGPHH_01707 3.7e-265 G Major Facilitator
GPHLGPHH_01708 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GPHLGPHH_01709 3.1e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPHLGPHH_01710 6.1e-260 G Major Facilitator
GPHLGPHH_01711 8.9e-176 K Transcriptional regulator, LacI family
GPHLGPHH_01712 5e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPHLGPHH_01713 5.4e-101 nqr 1.5.1.36 S reductase
GPHLGPHH_01714 5e-200 XK27_09615 S reductase
GPHLGPHH_01715 1.4e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GPHLGPHH_01717 7.9e-16 D nuclear chromosome segregation
GPHLGPHH_01718 4e-177 S FRG
GPHLGPHH_01719 2.4e-211 yfnA E Amino Acid
GPHLGPHH_01720 1.1e-87 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPHLGPHH_01721 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GPHLGPHH_01722 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GPHLGPHH_01723 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GPHLGPHH_01724 2.6e-194 coiA 3.6.4.12 S Competence protein
GPHLGPHH_01725 1.4e-267 pipD E Dipeptidase
GPHLGPHH_01726 3.1e-113 yjbH Q Thioredoxin
GPHLGPHH_01727 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
GPHLGPHH_01728 1.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPHLGPHH_01729 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
GPHLGPHH_01730 1.4e-18 L Transposase IS66 family
GPHLGPHH_01733 5.6e-107 yvyE 3.4.13.9 S YigZ family
GPHLGPHH_01734 3.6e-249 comFA L Helicase C-terminal domain protein
GPHLGPHH_01735 3.9e-114 comFC S Competence protein
GPHLGPHH_01736 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPHLGPHH_01737 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GPHLGPHH_01738 1.3e-145 potB P ABC transporter permease
GPHLGPHH_01739 6.5e-140 potC P ABC transporter permease
GPHLGPHH_01740 1.8e-206 potD P ABC transporter
GPHLGPHH_01741 7.9e-34
GPHLGPHH_01742 3.6e-65
GPHLGPHH_01743 9.5e-18
GPHLGPHH_01744 2.3e-31
GPHLGPHH_01745 8.7e-24 L Integrase
GPHLGPHH_01746 1.1e-13 K Transcriptional
GPHLGPHH_01747 1.4e-94 cadD P Cadmium resistance transporter
GPHLGPHH_01748 4.7e-55 cadX K Bacterial regulatory protein, arsR family
GPHLGPHH_01749 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPHLGPHH_01750 2.5e-181 arsB 1.20.4.1 P Sodium Bile acid symporter family
GPHLGPHH_01751 1.8e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
GPHLGPHH_01752 2.7e-62 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPHLGPHH_01753 2e-44 arsB 1.20.4.1 P Sodium Bile acid symporter family
GPHLGPHH_01754 4.9e-18 K Helix-turn-helix domain
GPHLGPHH_01755 2.6e-17 relB L RelB antitoxin
GPHLGPHH_01756 7.1e-273 S ABC transporter, ATP-binding protein
GPHLGPHH_01757 2.3e-142 S Putative ABC-transporter type IV
GPHLGPHH_01758 1.1e-104 NU mannosyl-glycoprotein
GPHLGPHH_01759 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
GPHLGPHH_01760 1.8e-226 S Uncharacterized protein conserved in bacteria (DUF2325)
GPHLGPHH_01761 8.9e-206 nrnB S DHHA1 domain
GPHLGPHH_01762 1e-30 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPHLGPHH_01763 1.8e-16 S Domain of unknown function (DUF4767)
GPHLGPHH_01764 5.2e-53
GPHLGPHH_01765 3.4e-118 yrkL S Flavodoxin-like fold
GPHLGPHH_01767 5.9e-64 yeaO S Protein of unknown function, DUF488
GPHLGPHH_01768 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GPHLGPHH_01769 1.2e-203 3.1.3.1 S associated with various cellular activities
GPHLGPHH_01770 9e-237 S Putative metallopeptidase domain
GPHLGPHH_01771 1.4e-47
GPHLGPHH_01772 0.0 pepO 3.4.24.71 O Peptidase family M13
GPHLGPHH_01773 2.7e-106 K Helix-turn-helix XRE-family like proteins
GPHLGPHH_01774 5.1e-87 ymdB S Macro domain protein
GPHLGPHH_01775 2.6e-195 EGP Major facilitator Superfamily
GPHLGPHH_01776 8.4e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPHLGPHH_01777 6.2e-10 K helix_turn_helix, mercury resistance
GPHLGPHH_01778 5.4e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPHLGPHH_01779 1.9e-155 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
GPHLGPHH_01780 0.0 ysaB V FtsX-like permease family
GPHLGPHH_01781 1.9e-133 macB2 V ABC transporter, ATP-binding protein
GPHLGPHH_01782 2.5e-178 T PhoQ Sensor
GPHLGPHH_01783 1.1e-124 K response regulator
GPHLGPHH_01784 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
GPHLGPHH_01785 1.8e-133 pnuC H nicotinamide mononucleotide transporter
GPHLGPHH_01786 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPHLGPHH_01787 2.1e-202
GPHLGPHH_01788 3.5e-52
GPHLGPHH_01789 9.1e-36
GPHLGPHH_01790 3.2e-36 yxkA S Phosphatidylethanolamine-binding protein
GPHLGPHH_01791 5.8e-13 yxkA S Phosphatidylethanolamine-binding protein
GPHLGPHH_01792 3.5e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
GPHLGPHH_01793 8.6e-176 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
GPHLGPHH_01794 2.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPHLGPHH_01795 9.6e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GPHLGPHH_01796 5e-179 galR K Transcriptional regulator
GPHLGPHH_01806 4.1e-98 2.3.1.128 K Acetyltransferase (GNAT) domain
GPHLGPHH_01807 1.1e-232 lmrB EGP Major facilitator Superfamily
GPHLGPHH_01808 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GPHLGPHH_01809 9.9e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPHLGPHH_01810 1.7e-157 sufD O Uncharacterized protein family (UPF0051)
GPHLGPHH_01811 2e-42 lytE M LysM domain protein
GPHLGPHH_01812 0.0 oppD EP Psort location Cytoplasmic, score
GPHLGPHH_01813 7.7e-86 lytE M LysM domain protein
GPHLGPHH_01814 1.1e-146 xth 3.1.11.2 L exodeoxyribonuclease III
GPHLGPHH_01815 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GPHLGPHH_01816 1.5e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
GPHLGPHH_01817 4.5e-152 yeaE S Aldo keto
GPHLGPHH_01818 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
GPHLGPHH_01819 4.6e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
GPHLGPHH_01820 2.5e-77 S Psort location Cytoplasmic, score
GPHLGPHH_01821 1.6e-54 S Short repeat of unknown function (DUF308)
GPHLGPHH_01822 1.6e-109 dedA S SNARE-like domain protein
GPHLGPHH_01823 2.8e-101 S Protein of unknown function (DUF1461)
GPHLGPHH_01824 5.5e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GPHLGPHH_01825 6.6e-93 yutD S Protein of unknown function (DUF1027)
GPHLGPHH_01826 4.7e-111 S Calcineurin-like phosphoesterase
GPHLGPHH_01827 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPHLGPHH_01828 7.9e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
GPHLGPHH_01830 1.2e-68
GPHLGPHH_01831 3.2e-41
GPHLGPHH_01832 3.4e-79 NU general secretion pathway protein
GPHLGPHH_01833 7.1e-47 comGC U competence protein ComGC
GPHLGPHH_01834 5.1e-182 comGB NU type II secretion system
GPHLGPHH_01835 4.9e-179 comGA NU Type II IV secretion system protein
GPHLGPHH_01836 5.9e-132 yebC K Transcriptional regulatory protein
GPHLGPHH_01837 8.7e-132
GPHLGPHH_01838 7.1e-181 ccpA K catabolite control protein A
GPHLGPHH_01839 3.2e-195 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GPHLGPHH_01840 2.5e-16
GPHLGPHH_01841 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPHLGPHH_01842 6.9e-148 ykuT M mechanosensitive ion channel
GPHLGPHH_01843 4.7e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
GPHLGPHH_01844 1.1e-74 ykuL S (CBS) domain
GPHLGPHH_01845 1.7e-93 S Phosphoesterase
GPHLGPHH_01846 6.3e-105 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPHLGPHH_01847 3.5e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPHLGPHH_01848 3e-96 yslB S Protein of unknown function (DUF2507)
GPHLGPHH_01849 6.1e-54 trxA O Belongs to the thioredoxin family
GPHLGPHH_01850 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPHLGPHH_01851 2.7e-86 cvpA S Colicin V production protein
GPHLGPHH_01852 6.1e-48 yrzB S Belongs to the UPF0473 family
GPHLGPHH_01853 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPHLGPHH_01854 4.1e-43 yrzL S Belongs to the UPF0297 family
GPHLGPHH_01855 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPHLGPHH_01856 6.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GPHLGPHH_01857 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
GPHLGPHH_01858 6.2e-31 yajC U Preprotein translocase
GPHLGPHH_01859 5e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GPHLGPHH_01860 1.1e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GPHLGPHH_01861 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GPHLGPHH_01862 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPHLGPHH_01863 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPHLGPHH_01864 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
GPHLGPHH_01865 3.8e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPHLGPHH_01866 9.6e-228 cinA 3.5.1.42 S Belongs to the CinA family
GPHLGPHH_01867 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPHLGPHH_01868 1.7e-137 ymfM S Helix-turn-helix domain
GPHLGPHH_01869 3e-248 ymfH S Peptidase M16
GPHLGPHH_01870 1.2e-225 ymfF S Peptidase M16 inactive domain protein
GPHLGPHH_01871 1.7e-159 aatB ET ABC transporter substrate-binding protein
GPHLGPHH_01872 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPHLGPHH_01873 3.2e-102 glnP P ABC transporter permease
GPHLGPHH_01874 8.7e-93 mreD M rod shape-determining protein MreD
GPHLGPHH_01875 3.5e-152 mreC M Involved in formation and maintenance of cell shape
GPHLGPHH_01876 1.7e-179 mreB D cell shape determining protein MreB
GPHLGPHH_01877 8e-122 radC L DNA repair protein
GPHLGPHH_01878 7.2e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GPHLGPHH_01879 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
GPHLGPHH_01880 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPHLGPHH_01881 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GPHLGPHH_01882 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
GPHLGPHH_01883 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
GPHLGPHH_01884 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GPHLGPHH_01885 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPHLGPHH_01886 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
GPHLGPHH_01887 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GPHLGPHH_01888 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPHLGPHH_01889 1.3e-72 L PFAM Integrase catalytic region
GPHLGPHH_01890 8.6e-47 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
GPHLGPHH_01892 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GPHLGPHH_01893 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
GPHLGPHH_01894 0.0 pacL 3.6.3.8 P P-type ATPase
GPHLGPHH_01895 9.9e-85 dps P Belongs to the Dps family
GPHLGPHH_01896 4.1e-176 yagE E amino acid
GPHLGPHH_01897 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
GPHLGPHH_01898 1.2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPHLGPHH_01899 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPHLGPHH_01900 6.4e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
GPHLGPHH_01901 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
GPHLGPHH_01913 8e-38 S Cytochrome B5
GPHLGPHH_01914 4.9e-60 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_01915 1.2e-286 mntH P H( )-stimulated, divalent metal cation uptake system
GPHLGPHH_01916 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
GPHLGPHH_01917 1.8e-84 ygfC K transcriptional regulator (TetR family)
GPHLGPHH_01918 2.1e-167 hrtB V ABC transporter permease
GPHLGPHH_01919 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
GPHLGPHH_01920 0.0 yhcA V ABC transporter, ATP-binding protein
GPHLGPHH_01921 2.5e-36
GPHLGPHH_01922 3.5e-49 czrA K Transcriptional regulator, ArsR family
GPHLGPHH_01923 6.3e-238 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPHLGPHH_01924 2.3e-47 M NlpC P60 family protein
GPHLGPHH_01925 8.7e-153 S Putative peptidoglycan binding domain
GPHLGPHH_01933 7.7e-22 K Helix-turn-helix XRE-family like proteins
GPHLGPHH_01934 1e-26 higB-2 S RelE toxin of RelE / RelB toxin-antitoxin system
GPHLGPHH_01936 3.8e-94 L Integrase
GPHLGPHH_01937 2.4e-36
GPHLGPHH_01938 4.5e-74 XK27_02070 S Nitroreductase family
GPHLGPHH_01939 1e-199
GPHLGPHH_01940 3.5e-167 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GPHLGPHH_01941 2.2e-41 hxlR K Transcriptional regulator, HxlR family
GPHLGPHH_01942 9.5e-123 L hmm pf00665
GPHLGPHH_01943 2e-58 L Helix-turn-helix domain
GPHLGPHH_01945 2.8e-87 D CobQ CobB MinD ParA nucleotide binding domain protein
GPHLGPHH_01946 1.2e-116 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPHLGPHH_01947 1.4e-37
GPHLGPHH_01948 2.9e-15
GPHLGPHH_01949 2e-86 yciB M ErfK YbiS YcfS YnhG
GPHLGPHH_01950 0.0 pepN 3.4.11.2 E aminopeptidase
GPHLGPHH_01951 9.9e-112 ylbE GM NAD dependent epimerase dehydratase family protein
GPHLGPHH_01952 3e-256 pepC 3.4.22.40 E aminopeptidase
GPHLGPHH_01953 2.2e-210 EGP Major facilitator Superfamily
GPHLGPHH_01954 4.4e-231
GPHLGPHH_01955 4.4e-82 K Transcriptional regulator, HxlR family
GPHLGPHH_01956 2.6e-106 XK27_02070 S Nitroreductase family
GPHLGPHH_01957 1.8e-50 hxlR K Transcriptional regulator, HxlR family
GPHLGPHH_01958 1.2e-120 GM NmrA-like family
GPHLGPHH_01959 1.5e-74 elaA S Gnat family
GPHLGPHH_01960 6.5e-14 S Cytochrome B5
GPHLGPHH_01961 3.3e-219 yxjG_1 E methionine synthase, vitamin-B12 independent
GPHLGPHH_01963 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPHLGPHH_01964 8.6e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPHLGPHH_01965 5.1e-238 E amino acid
GPHLGPHH_01966 9.5e-32 npp S type I phosphodiesterase nucleotide pyrophosphatase
GPHLGPHH_01967 1.5e-67 npp S type I phosphodiesterase nucleotide pyrophosphatase
GPHLGPHH_01968 3.2e-62 npp S type I phosphodiesterase nucleotide pyrophosphatase
GPHLGPHH_01969 2.7e-56 npp S type I phosphodiesterase nucleotide pyrophosphatase
GPHLGPHH_01970 4.2e-84 yxiO S Vacuole effluxer Atg22 like
GPHLGPHH_01971 1.2e-74 yxiO S Vacuole effluxer Atg22 like
GPHLGPHH_01974 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPHLGPHH_01975 1.5e-28
GPHLGPHH_01976 2.9e-111 frnE Q DSBA-like thioredoxin domain
GPHLGPHH_01977 8.8e-164 I alpha/beta hydrolase fold
GPHLGPHH_01978 8.5e-20 K Helix-turn-helix XRE-family like proteins
GPHLGPHH_01979 3.3e-35 S Phage derived protein Gp49-like (DUF891)
GPHLGPHH_01980 2.5e-203 3.5.1.104 M hydrolase, family 25
GPHLGPHH_01981 9.3e-53 S Bacteriophage holin of superfamily 6 (Holin_LLH)
GPHLGPHH_01982 4.4e-35 S Bacteriophage holin family
GPHLGPHH_01986 3.1e-97 S Domain of unknown function (DUF2479)
GPHLGPHH_01988 2.7e-261 3.4.24.40 M Peptidase family M23
GPHLGPHH_01989 1e-156 S Phage tail protein
GPHLGPHH_01990 0.0 M Phage tail tape measure protein TP901
GPHLGPHH_01991 1.5e-19
GPHLGPHH_01992 1e-22
GPHLGPHH_01993 9.5e-107
GPHLGPHH_01994 3.2e-74
GPHLGPHH_01995 1.2e-45 S Bacteriophage HK97-gp10, putative tail-component
GPHLGPHH_01996 6.6e-40 S Phage head-tail joining protein
GPHLGPHH_01997 9.7e-68 S Phage gp6-like head-tail connector protein
GPHLGPHH_01998 5.8e-74 S Phage capsid family
GPHLGPHH_01999 3.7e-123 S Phage capsid family
GPHLGPHH_02000 1.7e-114 pi136 S Caudovirus prohead serine protease
GPHLGPHH_02001 1.8e-237 S Phage portal protein
GPHLGPHH_02004 0.0 terL S overlaps another CDS with the same product name
GPHLGPHH_02005 7.6e-77 terS L Phage terminase, small subunit
GPHLGPHH_02006 6.4e-151 L HNH nucleases
GPHLGPHH_02008 1.1e-07
GPHLGPHH_02009 9.1e-12
GPHLGPHH_02010 4.2e-83 arpU S Phage transcriptional regulator, ArpU family
GPHLGPHH_02012 3e-71 XK27_00160 S Domain of unknown function (DUF5052)
GPHLGPHH_02016 1.3e-126
GPHLGPHH_02017 3.1e-69
GPHLGPHH_02019 2.3e-41 S HNH endonuclease
GPHLGPHH_02020 5.8e-10
GPHLGPHH_02022 2.4e-138 L Belongs to the 'phage' integrase family
GPHLGPHH_02023 4.8e-87 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
GPHLGPHH_02024 2.4e-111 L DnaD domain protein
GPHLGPHH_02027 1.7e-19
GPHLGPHH_02028 1.8e-16 K Cro/C1-type HTH DNA-binding domain
GPHLGPHH_02029 2.6e-22 S Uncharacterized protein conserved in bacteria (DUF2188)
GPHLGPHH_02032 3.3e-11 S BIO14.03 Phage related functions and prophages. 98 identical to Orf10 of bacteriophage Tuc2009
GPHLGPHH_02036 6.3e-10 K Helix-turn-helix XRE-family like proteins
GPHLGPHH_02037 1.8e-79 3.4.21.88 K Peptidase S24-like
GPHLGPHH_02038 9.3e-09
GPHLGPHH_02041 1.7e-20
GPHLGPHH_02043 5.7e-38
GPHLGPHH_02046 1.2e-67 S Domain of unknown function (DUF4393)
GPHLGPHH_02048 4.6e-141 L Belongs to the 'phage' integrase family
GPHLGPHH_02050 8.9e-41 yrvD S Pfam:DUF1049
GPHLGPHH_02051 3.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
GPHLGPHH_02052 2.1e-90 ntd 2.4.2.6 F Nucleoside
GPHLGPHH_02053 2e-18
GPHLGPHH_02054 2.2e-162 S Alpha/beta hydrolase of unknown function (DUF915)
GPHLGPHH_02055 4.7e-114 yviA S Protein of unknown function (DUF421)
GPHLGPHH_02056 7e-72 S Protein of unknown function (DUF3290)
GPHLGPHH_02057 2.3e-41 ybaN S Protein of unknown function (DUF454)
GPHLGPHH_02058 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPHLGPHH_02059 7.2e-158 endA V DNA/RNA non-specific endonuclease
GPHLGPHH_02060 1.9e-253 yifK E Amino acid permease
GPHLGPHH_02062 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPHLGPHH_02063 1.1e-228 N Uncharacterized conserved protein (DUF2075)
GPHLGPHH_02064 5.1e-122 S SNARE associated Golgi protein
GPHLGPHH_02065 3.5e-45 uvrA3 L excinuclease ABC, A subunit
GPHLGPHH_02066 4.9e-273 pipD E Dipeptidase
GPHLGPHH_02067 7.6e-311 yjbQ P TrkA C-terminal domain protein
GPHLGPHH_02068 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GPHLGPHH_02069 2.5e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPHLGPHH_02070 7.1e-89
GPHLGPHH_02071 4.7e-35
GPHLGPHH_02072 4.6e-100 K DNA-templated transcription, initiation
GPHLGPHH_02073 4e-28
GPHLGPHH_02074 6.9e-178 ycsG P Natural resistance-associated macrophage protein
GPHLGPHH_02075 7.6e-103 ycsF S LamB/YcsF family
GPHLGPHH_02076 7.8e-207 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
GPHLGPHH_02077 3.8e-38 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GPHLGPHH_02078 8.1e-108 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
GPHLGPHH_02079 5.9e-84 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
GPHLGPHH_02080 2e-42 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPHLGPHH_02082 1.4e-107 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPHLGPHH_02083 5.2e-54 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPHLGPHH_02084 1.6e-151 tesE Q hydratase
GPHLGPHH_02085 4.1e-64 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GPHLGPHH_02086 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GPHLGPHH_02087 1.4e-297 mco Q Multicopper oxidase
GPHLGPHH_02088 1.7e-127 L PFAM Integrase catalytic region
GPHLGPHH_02089 4.5e-121 L Belongs to the 'phage' integrase family
GPHLGPHH_02090 1.9e-10
GPHLGPHH_02094 2.5e-64 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_02095 4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GPHLGPHH_02097 1.7e-218 S cog cog1373
GPHLGPHH_02098 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
GPHLGPHH_02099 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GPHLGPHH_02100 1.1e-158 EG EamA-like transporter family
GPHLGPHH_02101 6.4e-36 Q pyridine nucleotide-disulphide oxidoreductase
GPHLGPHH_02102 0.0 helD 3.6.4.12 L DNA helicase
GPHLGPHH_02103 8.8e-116 dedA S SNARE associated Golgi protein
GPHLGPHH_02104 5.5e-126 3.1.3.73 G phosphoglycerate mutase
GPHLGPHH_02105 6.6e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPHLGPHH_02106 2.1e-33 S Transglycosylase associated protein
GPHLGPHH_02108 2.7e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPHLGPHH_02109 2.4e-218 V domain protein
GPHLGPHH_02110 3.5e-94 K Transcriptional regulator (TetR family)
GPHLGPHH_02111 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
GPHLGPHH_02112 1e-148
GPHLGPHH_02113 3.1e-17 3.2.1.14 GH18
GPHLGPHH_02114 2.1e-81 zur P Belongs to the Fur family
GPHLGPHH_02115 2.1e-97 gmk2 2.7.4.8 F Guanylate kinase
GPHLGPHH_02116 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
GPHLGPHH_02117 1.8e-254 yfnA E Amino Acid
GPHLGPHH_02118 5.7e-231 EGP Sugar (and other) transporter
GPHLGPHH_02119 5.6e-48 XK27_01125 L PFAM IS66 Orf2 family protein
GPHLGPHH_02120 1.5e-147 S Hydrolases of the alpha beta superfamily
GPHLGPHH_02121 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
GPHLGPHH_02122 4.4e-77 ctsR K Belongs to the CtsR family
GPHLGPHH_02123 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GPHLGPHH_02124 3e-110 K Bacterial regulatory proteins, tetR family
GPHLGPHH_02125 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPHLGPHH_02126 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPHLGPHH_02127 2.3e-199 ykiI
GPHLGPHH_02128 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
GPHLGPHH_02129 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPHLGPHH_02130 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GPHLGPHH_02131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPHLGPHH_02132 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GPHLGPHH_02133 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPHLGPHH_02134 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
GPHLGPHH_02135 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GPHLGPHH_02136 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPHLGPHH_02137 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPHLGPHH_02138 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPHLGPHH_02139 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPHLGPHH_02140 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPHLGPHH_02141 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
GPHLGPHH_02142 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPHLGPHH_02143 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPHLGPHH_02144 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPHLGPHH_02145 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPHLGPHH_02146 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPHLGPHH_02147 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPHLGPHH_02148 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPHLGPHH_02149 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPHLGPHH_02150 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPHLGPHH_02151 2.9e-24 rpmD J Ribosomal protein L30
GPHLGPHH_02152 1.5e-63 rplO J Binds to the 23S rRNA
GPHLGPHH_02153 1.7e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GPHLGPHH_02154 4.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GPHLGPHH_02155 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPHLGPHH_02156 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GPHLGPHH_02157 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPHLGPHH_02158 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPHLGPHH_02159 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPHLGPHH_02160 1.1e-62 rplQ J Ribosomal protein L17
GPHLGPHH_02161 2.7e-138 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPHLGPHH_02162 7.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPHLGPHH_02163 3.7e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPHLGPHH_02164 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GPHLGPHH_02165 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPHLGPHH_02166 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
GPHLGPHH_02167 1.4e-139 IQ reductase
GPHLGPHH_02168 4.4e-109 acmC 3.2.1.96 NU mannosyl-glycoprotein
GPHLGPHH_02169 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GPHLGPHH_02170 3.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPHLGPHH_02171 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GPHLGPHH_02172 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPHLGPHH_02173 1.2e-202 camS S sex pheromone
GPHLGPHH_02174 7e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPHLGPHH_02175 9.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GPHLGPHH_02176 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPHLGPHH_02177 1.5e-186 yegS 2.7.1.107 G Lipid kinase
GPHLGPHH_02178 1.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPHLGPHH_02179 6.8e-39 S Protein of unknown function (DUF3021)
GPHLGPHH_02180 7.9e-63 K LytTr DNA-binding domain
GPHLGPHH_02181 3.7e-122 cylB V ABC-2 type transporter
GPHLGPHH_02182 9.4e-126 cylA V ABC transporter
GPHLGPHH_02183 4.9e-253 L Recombinase
GPHLGPHH_02184 7.7e-225 L Recombinase zinc beta ribbon domain
GPHLGPHH_02185 4.8e-19
GPHLGPHH_02186 4.8e-30 S Bacteriophage holin family
GPHLGPHH_02187 7.2e-54 S Phage head-tail joining protein
GPHLGPHH_02188 1.3e-39 S Phage gp6-like head-tail connector protein
GPHLGPHH_02189 8.8e-172 S Phage capsid family
GPHLGPHH_02190 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPHLGPHH_02191 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
GPHLGPHH_02192 6.6e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPHLGPHH_02193 1.2e-102 pncA Q Isochorismatase family
GPHLGPHH_02194 1.7e-31 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GPHLGPHH_02195 4.8e-199 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GPHLGPHH_02196 8.6e-23 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GPHLGPHH_02197 1.9e-138 S Belongs to the UPF0246 family
GPHLGPHH_02198 1.2e-137 S Membrane
GPHLGPHH_02199 6.8e-74 4.4.1.5 E Glyoxalase
GPHLGPHH_02200 1.7e-20
GPHLGPHH_02201 3.5e-85 yueI S Protein of unknown function (DUF1694)
GPHLGPHH_02202 1.8e-240 rarA L recombination factor protein RarA
GPHLGPHH_02203 4.4e-46
GPHLGPHH_02204 4.3e-83 usp6 T universal stress protein
GPHLGPHH_02205 1.4e-203 araR K Transcriptional regulator
GPHLGPHH_02206 1.9e-155 ytbE 1.1.1.346 S Aldo keto reductase
GPHLGPHH_02207 9.2e-29 maa 2.3.1.79 S Maltose O-acetyltransferase
GPHLGPHH_02208 1e-50 maa 2.3.1.79 S Maltose O-acetyltransferase
GPHLGPHH_02209 2.2e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
GPHLGPHH_02210 1.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GPHLGPHH_02211 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
GPHLGPHH_02212 1.2e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GPHLGPHH_02213 3.7e-146 2.3.1.19 K Helix-turn-helix XRE-family like proteins
GPHLGPHH_02214 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GPHLGPHH_02215 1.4e-47 gcvH E glycine cleavage
GPHLGPHH_02216 1.1e-220 rodA D Belongs to the SEDS family
GPHLGPHH_02217 1e-31 S Protein of unknown function (DUF2969)
GPHLGPHH_02218 1.9e-178 mbl D Cell shape determining protein MreB Mrl
GPHLGPHH_02219 3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPHLGPHH_02220 1.3e-33 ywzB S Protein of unknown function (DUF1146)
GPHLGPHH_02221 1e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GPHLGPHH_02222 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPHLGPHH_02223 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPHLGPHH_02224 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPHLGPHH_02225 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPHLGPHH_02226 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPHLGPHH_02227 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPHLGPHH_02228 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
GPHLGPHH_02229 1.7e-232 pyrP F Permease
GPHLGPHH_02230 2.6e-130 yibF S overlaps another CDS with the same product name
GPHLGPHH_02231 2e-192 yibE S overlaps another CDS with the same product name
GPHLGPHH_02232 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPHLGPHH_02233 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPHLGPHH_02234 3.9e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPHLGPHH_02235 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GPHLGPHH_02236 6.1e-165 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GPHLGPHH_02237 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPHLGPHH_02238 6e-108 tdk 2.7.1.21 F thymidine kinase
GPHLGPHH_02239 1.7e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
GPHLGPHH_02240 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
GPHLGPHH_02241 3e-10
GPHLGPHH_02242 6.1e-223 arcD U Amino acid permease
GPHLGPHH_02243 2.4e-259 E Arginine ornithine antiporter
GPHLGPHH_02244 2.7e-79 argR K Regulates arginine biosynthesis genes
GPHLGPHH_02245 2e-217 arcA 3.5.3.6 E Arginine
GPHLGPHH_02246 7.7e-183 ampC V Beta-lactamase
GPHLGPHH_02247 1.8e-19
GPHLGPHH_02248 4.9e-214 M domain protein
GPHLGPHH_02249 3.4e-278 M domain protein
GPHLGPHH_02250 3.1e-92
GPHLGPHH_02251 2e-133 L Belongs to the 'phage' integrase family
GPHLGPHH_02252 2e-15 S sequence-specific DNA binding
GPHLGPHH_02253 1.6e-14
GPHLGPHH_02254 1.5e-45 S Phage regulatory protein Rha (Phage_pRha)
GPHLGPHH_02257 7.7e-09
GPHLGPHH_02261 2.3e-14 L DnaD domain protein
GPHLGPHH_02264 5.2e-66
GPHLGPHH_02267 4.1e-54
GPHLGPHH_02269 1.7e-100 yjcE P Sodium proton antiporter
GPHLGPHH_02270 1.1e-78 yjcE P Sodium proton antiporter
GPHLGPHH_02271 2.5e-39 yjcE P Sodium proton antiporter
GPHLGPHH_02272 2.3e-56
GPHLGPHH_02274 4.5e-85
GPHLGPHH_02275 0.0 copA 3.6.3.54 P P-type ATPase
GPHLGPHH_02276 4.2e-54 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GPHLGPHH_02277 2.9e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GPHLGPHH_02278 3.1e-159 EG EamA-like transporter family
GPHLGPHH_02279 3.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
GPHLGPHH_02280 2.2e-190 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPHLGPHH_02281 3.6e-154 KT YcbB domain
GPHLGPHH_02282 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GPHLGPHH_02284 1e-25
GPHLGPHH_02285 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
GPHLGPHH_02286 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
GPHLGPHH_02287 4.1e-153 glcU U sugar transport
GPHLGPHH_02288 1.7e-271 yclK 2.7.13.3 T Histidine kinase
GPHLGPHH_02289 1.6e-134 K response regulator
GPHLGPHH_02291 1.3e-76 lytE M Lysin motif
GPHLGPHH_02292 1.1e-147 XK27_02985 S Cof-like hydrolase
GPHLGPHH_02293 1.8e-78 K Transcriptional regulator
GPHLGPHH_02294 0.0 oatA I Acyltransferase
GPHLGPHH_02295 5.6e-52
GPHLGPHH_02296 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GPHLGPHH_02297 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPHLGPHH_02298 1.7e-125 ybbR S YbbR-like protein
GPHLGPHH_02299 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPHLGPHH_02300 3.7e-249 fucP G Major Facilitator Superfamily
GPHLGPHH_02301 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GPHLGPHH_02302 2.5e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPHLGPHH_02303 3.6e-168 murB 1.3.1.98 M Cell wall formation
GPHLGPHH_02304 2.5e-100 dnaQ 2.7.7.7 L DNA polymerase III
GPHLGPHH_02305 1.3e-75 S PAS domain
GPHLGPHH_02306 6.1e-88 K Acetyltransferase (GNAT) domain
GPHLGPHH_02307 1.3e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
GPHLGPHH_02308 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GPHLGPHH_02309 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPHLGPHH_02310 6.3e-105 yxjI
GPHLGPHH_02311 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GPHLGPHH_02312 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GPHLGPHH_02313 4.8e-145 est 3.1.1.1 S Serine aminopeptidase, S33
GPHLGPHH_02314 1.8e-34 secG U Preprotein translocase
GPHLGPHH_02315 4.4e-291 clcA P chloride
GPHLGPHH_02316 6.2e-244 yifK E Amino acid permease
GPHLGPHH_02317 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GPHLGPHH_02318 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPHLGPHH_02319 1.7e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GPHLGPHH_02320 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPHLGPHH_02322 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)