ORF_ID e_value Gene_name EC_number CAZy COGs Description
CIMHLLIM_00019 2.1e-24
CIMHLLIM_00020 9.5e-59
CIMHLLIM_00021 1.3e-70
CIMHLLIM_00022 9.3e-32
CIMHLLIM_00023 9.8e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
CIMHLLIM_00024 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CIMHLLIM_00025 2e-100 fic D Fic/DOC family
CIMHLLIM_00026 2.8e-70
CIMHLLIM_00027 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
CIMHLLIM_00028 2.1e-88 L nuclease
CIMHLLIM_00029 2.7e-39
CIMHLLIM_00030 0.0 ydaO E amino acid
CIMHLLIM_00031 4.5e-302 ybeC E amino acid
CIMHLLIM_00032 2e-80 S Aminoacyl-tRNA editing domain
CIMHLLIM_00033 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CIMHLLIM_00034 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIMHLLIM_00036 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CIMHLLIM_00037 0.0 uup S ABC transporter, ATP-binding protein
CIMHLLIM_00038 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIMHLLIM_00039 5.9e-227 mtnE 2.6.1.83 E Aminotransferase
CIMHLLIM_00040 1.6e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
CIMHLLIM_00041 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CIMHLLIM_00042 7.6e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CIMHLLIM_00043 2e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIMHLLIM_00044 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CIMHLLIM_00045 2e-100 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
CIMHLLIM_00046 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
CIMHLLIM_00047 1.7e-67 L Belongs to the 'phage' integrase family
CIMHLLIM_00048 8.1e-149 3.2.1.18 GH33 M Rib/alpha-like repeat
CIMHLLIM_00049 1.2e-102 pncA Q Isochorismatase family
CIMHLLIM_00050 6.6e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIMHLLIM_00051 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
CIMHLLIM_00052 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CIMHLLIM_00053 8.8e-172 S Phage capsid family
CIMHLLIM_00054 1.3e-39 S Phage gp6-like head-tail connector protein
CIMHLLIM_00055 7.2e-54 S Phage head-tail joining protein
CIMHLLIM_00056 2.4e-29 S Bacteriophage holin family
CIMHLLIM_00057 8.2e-19
CIMHLLIM_00058 1.3e-68 L Recombinase zinc beta ribbon domain
CIMHLLIM_00059 4.7e-19 L Recombinase zinc beta ribbon domain
CIMHLLIM_00060 1.7e-21 L recombinase activity
CIMHLLIM_00061 2.6e-67 L Recombinase
CIMHLLIM_00062 1.5e-69 L Recombinase
CIMHLLIM_00063 2e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
CIMHLLIM_00064 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
CIMHLLIM_00065 6.3e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
CIMHLLIM_00066 5.2e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
CIMHLLIM_00067 1.2e-94 dps P Belongs to the Dps family
CIMHLLIM_00068 7.9e-35 copZ C Heavy-metal-associated domain
CIMHLLIM_00069 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
CIMHLLIM_00070 2e-163 L PFAM Integrase catalytic region
CIMHLLIM_00071 1.8e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIMHLLIM_00073 4.9e-207 L helicase activity
CIMHLLIM_00074 1e-120 L helicase activity
CIMHLLIM_00075 1.2e-68 K DNA binding
CIMHLLIM_00076 1e-88 L Recombinase
CIMHLLIM_00077 3.5e-174 S Domain of unknown function (DUF389)
CIMHLLIM_00078 5.3e-54 U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CIMHLLIM_00079 7.4e-25 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CIMHLLIM_00080 2.6e-176 S FRG
CIMHLLIM_00081 2.4e-211 yfnA E Amino Acid
CIMHLLIM_00082 7.1e-84 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIMHLLIM_00083 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIMHLLIM_00084 6e-115 comFC S Competence protein
CIMHLLIM_00085 3.6e-249 comFA L Helicase C-terminal domain protein
CIMHLLIM_00086 2.1e-106 yvyE 3.4.13.9 S YigZ family
CIMHLLIM_00087 8.2e-115
CIMHLLIM_00088 3.9e-135 V ABC transporter
CIMHLLIM_00089 1.7e-210 EGP Major facilitator Superfamily
CIMHLLIM_00090 4.2e-256 G PTS system Galactitol-specific IIC component
CIMHLLIM_00091 4.4e-23 1.6.5.5 C Zinc-binding dehydrogenase
CIMHLLIM_00092 4.1e-87 1.6.5.5 C Zinc-binding dehydrogenase
CIMHLLIM_00093 3.2e-158
CIMHLLIM_00094 1e-72 K Transcriptional regulator
CIMHLLIM_00095 1.7e-187 D Alpha beta
CIMHLLIM_00096 6.4e-52 ypaA S Protein of unknown function (DUF1304)
CIMHLLIM_00097 0.0 yjcE P Sodium proton antiporter
CIMHLLIM_00098 1.6e-52 yvlA
CIMHLLIM_00099 6.6e-111 P Cobalt transport protein
CIMHLLIM_00100 4.4e-250 cbiO1 S ABC transporter, ATP-binding protein
CIMHLLIM_00101 7.9e-97 S ABC-type cobalt transport system, permease component
CIMHLLIM_00102 3.3e-133 S membrane transporter protein
CIMHLLIM_00103 6.2e-114 IQ KR domain
CIMHLLIM_00104 2e-09 IQ KR domain
CIMHLLIM_00105 8.8e-15
CIMHLLIM_00107 1.5e-169 whiA K May be required for sporulation
CIMHLLIM_00108 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CIMHLLIM_00109 1.2e-160 rapZ S Displays ATPase and GTPase activities
CIMHLLIM_00110 2.7e-244 steT E amino acid
CIMHLLIM_00111 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CIMHLLIM_00112 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CIMHLLIM_00113 2e-13
CIMHLLIM_00114 5.1e-116 yfbR S HD containing hydrolase-like enzyme
CIMHLLIM_00115 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CIMHLLIM_00116 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
CIMHLLIM_00117 1.9e-161 aatB ET PFAM extracellular solute-binding protein, family 3
CIMHLLIM_00118 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CIMHLLIM_00119 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CIMHLLIM_00120 2.7e-168 lutA C Cysteine-rich domain
CIMHLLIM_00121 3.5e-293 lutB C 4Fe-4S dicluster domain
CIMHLLIM_00122 4.6e-137 yrjD S LUD domain
CIMHLLIM_00123 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CIMHLLIM_00124 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CIMHLLIM_00125 2.1e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIMHLLIM_00126 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CIMHLLIM_00127 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
CIMHLLIM_00128 7.7e-31 KT PspC domain protein
CIMHLLIM_00129 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIMHLLIM_00130 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CIMHLLIM_00131 1.4e-153 EG EamA-like transporter family
CIMHLLIM_00132 2.1e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
CIMHLLIM_00133 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIMHLLIM_00134 3.6e-154 KT YcbB domain
CIMHLLIM_00135 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
CIMHLLIM_00137 1e-25
CIMHLLIM_00138 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
CIMHLLIM_00139 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
CIMHLLIM_00140 4.1e-153 glcU U sugar transport
CIMHLLIM_00141 5.8e-272 yclK 2.7.13.3 T Histidine kinase
CIMHLLIM_00142 1.6e-134 K response regulator
CIMHLLIM_00144 1.3e-76 lytE M Lysin motif
CIMHLLIM_00145 1.1e-147 XK27_02985 S Cof-like hydrolase
CIMHLLIM_00146 1.8e-78 K Transcriptional regulator
CIMHLLIM_00147 0.0 oatA I Acyltransferase
CIMHLLIM_00148 5.6e-52
CIMHLLIM_00149 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CIMHLLIM_00150 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIMHLLIM_00151 1.7e-125 ybbR S YbbR-like protein
CIMHLLIM_00152 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CIMHLLIM_00153 3.4e-247 fucP G Major Facilitator Superfamily
CIMHLLIM_00154 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CIMHLLIM_00155 1.1e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIMHLLIM_00156 3e-167 murB 1.3.1.98 M Cell wall formation
CIMHLLIM_00157 3.9e-101 dnaQ 2.7.7.7 L DNA polymerase III
CIMHLLIM_00158 2.2e-75 S PAS domain
CIMHLLIM_00159 4.4e-86 K Acetyltransferase (GNAT) domain
CIMHLLIM_00160 2.2e-79 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
CIMHLLIM_00161 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CIMHLLIM_00162 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CIMHLLIM_00163 9.1e-104 yxjI
CIMHLLIM_00164 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CIMHLLIM_00165 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CIMHLLIM_00166 3.2e-141 est 3.1.1.1 S Serine aminopeptidase, S33
CIMHLLIM_00167 1.8e-34 secG U Preprotein translocase
CIMHLLIM_00168 9e-292 clcA P chloride
CIMHLLIM_00169 1.2e-244 yifK E Amino acid permease
CIMHLLIM_00170 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CIMHLLIM_00171 4.5e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIMHLLIM_00172 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CIMHLLIM_00173 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CIMHLLIM_00175 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CIMHLLIM_00176 9.4e-17
CIMHLLIM_00177 5.1e-159 K Transcriptional regulator
CIMHLLIM_00178 3.8e-85 lacA S transferase hexapeptide repeat
CIMHLLIM_00179 3.1e-133 S Hydrolases of the alpha beta superfamily
CIMHLLIM_00180 2.6e-12 S Alpha beta hydrolase
CIMHLLIM_00181 1.7e-89 S Alpha beta hydrolase
CIMHLLIM_00182 1.7e-153 tesE Q hydratase
CIMHLLIM_00183 6.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CIMHLLIM_00184 2.4e-228 aadAT EK Aminotransferase, class I
CIMHLLIM_00185 2.3e-155 ypuA S Protein of unknown function (DUF1002)
CIMHLLIM_00186 7.5e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
CIMHLLIM_00187 9.3e-145 K Transcriptional regulator
CIMHLLIM_00188 2.3e-159 akr5f 1.1.1.346 S reductase
CIMHLLIM_00189 7.5e-99 qorB 1.6.5.2 GM NmrA-like family
CIMHLLIM_00190 4.2e-59 yneR
CIMHLLIM_00191 7.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
CIMHLLIM_00192 1.6e-138 T EAL domain
CIMHLLIM_00193 2.2e-246 pgaC GT2 M Glycosyl transferase
CIMHLLIM_00194 3.7e-82
CIMHLLIM_00195 7.6e-195 2.7.7.65 T GGDEF domain
CIMHLLIM_00196 2.2e-120 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
CIMHLLIM_00197 1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
CIMHLLIM_00198 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
CIMHLLIM_00199 6.1e-39 folT S ECF transporter, substrate-specific component
CIMHLLIM_00200 5.5e-48 K Transcriptional regulator
CIMHLLIM_00201 0.0 pepN 3.4.11.2 E aminopeptidase
CIMHLLIM_00202 1.8e-84 ylbE GM NAD dependent epimerase dehydratase family protein
CIMHLLIM_00203 1.3e-12 ylbE GM NAD dependent epimerase dehydratase family protein
CIMHLLIM_00204 8.8e-256 pepC 3.4.22.40 E aminopeptidase
CIMHLLIM_00205 2.2e-210 EGP Major facilitator Superfamily
CIMHLLIM_00206 6.8e-232
CIMHLLIM_00207 4e-83 K Transcriptional regulator, HxlR family
CIMHLLIM_00208 4.1e-107 XK27_02070 S Nitroreductase family
CIMHLLIM_00209 1.8e-50 hxlR K Transcriptional regulator, HxlR family
CIMHLLIM_00210 1.2e-120 GM NmrA-like family
CIMHLLIM_00211 1.6e-73 elaA S Gnat family
CIMHLLIM_00212 5.7e-36 S Cytochrome B5
CIMHLLIM_00213 1.3e-218 yxjG_1 E methionine synthase, vitamin-B12 independent
CIMHLLIM_00215 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIMHLLIM_00216 8.6e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIMHLLIM_00217 1.5e-237 E amino acid
CIMHLLIM_00218 2.8e-31 npp S type I phosphodiesterase nucleotide pyrophosphatase
CIMHLLIM_00219 1.7e-47 npp S type I phosphodiesterase nucleotide pyrophosphatase
CIMHLLIM_00220 1.1e-101 npp S type I phosphodiesterase nucleotide pyrophosphatase
CIMHLLIM_00221 4.2e-84 yxiO S Vacuole effluxer Atg22 like
CIMHLLIM_00222 1.2e-74 yxiO S Vacuole effluxer Atg22 like
CIMHLLIM_00225 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIMHLLIM_00226 1.5e-28
CIMHLLIM_00227 9.8e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIMHLLIM_00228 9.6e-186 yegS 2.7.1.107 G Lipid kinase
CIMHLLIM_00229 9.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIMHLLIM_00230 9.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CIMHLLIM_00231 7e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIMHLLIM_00232 1.2e-202 camS S sex pheromone
CIMHLLIM_00233 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIMHLLIM_00234 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CIMHLLIM_00235 2.1e-210 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CIMHLLIM_00236 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CIMHLLIM_00237 1.5e-112 acmC 3.2.1.96 NU mannosyl-glycoprotein
CIMHLLIM_00238 8e-140 IQ reductase
CIMHLLIM_00239 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
CIMHLLIM_00240 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CIMHLLIM_00241 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CIMHLLIM_00242 1.7e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIMHLLIM_00243 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIMHLLIM_00244 4.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIMHLLIM_00245 1.1e-62 rplQ J Ribosomal protein L17
CIMHLLIM_00246 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIMHLLIM_00247 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIMHLLIM_00248 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIMHLLIM_00249 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CIMHLLIM_00250 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CIMHLLIM_00251 4.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CIMHLLIM_00252 1.7e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CIMHLLIM_00253 1.5e-63 rplO J Binds to the 23S rRNA
CIMHLLIM_00254 2.9e-24 rpmD J Ribosomal protein L30
CIMHLLIM_00255 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIMHLLIM_00256 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIMHLLIM_00257 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CIMHLLIM_00258 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CIMHLLIM_00259 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIMHLLIM_00260 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIMHLLIM_00261 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIMHLLIM_00262 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CIMHLLIM_00263 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIMHLLIM_00264 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
CIMHLLIM_00265 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIMHLLIM_00266 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CIMHLLIM_00267 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIMHLLIM_00268 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIMHLLIM_00269 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIMHLLIM_00270 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CIMHLLIM_00271 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
CIMHLLIM_00272 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CIMHLLIM_00273 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CIMHLLIM_00274 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIMHLLIM_00275 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CIMHLLIM_00276 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CIMHLLIM_00277 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
CIMHLLIM_00278 2.3e-199 ykiI
CIMHLLIM_00279 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIMHLLIM_00280 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIMHLLIM_00281 3e-110 K Bacterial regulatory proteins, tetR family
CIMHLLIM_00282 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CIMHLLIM_00283 4.4e-77 ctsR K Belongs to the CtsR family
CIMHLLIM_00284 8e-196 adhP 1.1.1.1 C alcohol dehydrogenase
CIMHLLIM_00285 1.5e-147 S Hydrolases of the alpha beta superfamily
CIMHLLIM_00286 3.7e-56 ltrA S Bacterial low temperature requirement A protein (LtrA)
CIMHLLIM_00287 2.6e-43 ltrA S Bacterial low temperature requirement A protein (LtrA)
CIMHLLIM_00288 1.6e-79 uspA T universal stress protein
CIMHLLIM_00289 4e-78 K AsnC family
CIMHLLIM_00290 4.5e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CIMHLLIM_00291 9.2e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
CIMHLLIM_00292 9.4e-27 L PFAM Integrase catalytic region
CIMHLLIM_00293 6.2e-10 K helix_turn_helix, mercury resistance
CIMHLLIM_00294 1.1e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CIMHLLIM_00295 3.8e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CIMHLLIM_00296 0.0 ysaB V FtsX-like permease family
CIMHLLIM_00297 2.9e-134 macB2 V ABC transporter, ATP-binding protein
CIMHLLIM_00298 5.3e-181 T PhoQ Sensor
CIMHLLIM_00299 5.4e-124 K response regulator
CIMHLLIM_00300 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
CIMHLLIM_00301 2.4e-133 pnuC H nicotinamide mononucleotide transporter
CIMHLLIM_00302 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIMHLLIM_00303 6.2e-202
CIMHLLIM_00304 3.5e-52
CIMHLLIM_00305 9.1e-36
CIMHLLIM_00306 3.1e-92 yxkA S Phosphatidylethanolamine-binding protein
CIMHLLIM_00307 1.2e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
CIMHLLIM_00308 2.5e-175 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
CIMHLLIM_00309 1.6e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CIMHLLIM_00310 1.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CIMHLLIM_00311 5.4e-181 galR K Transcriptional regulator
CIMHLLIM_00313 2.5e-64 XK27_01125 L PFAM IS66 Orf2 family protein
CIMHLLIM_00315 7.9e-14 L PFAM Integrase catalytic region
CIMHLLIM_00316 4.3e-08 S Acyltransferase family
CIMHLLIM_00317 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CIMHLLIM_00318 5.5e-45 yitW S Pfam:DUF59
CIMHLLIM_00319 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CIMHLLIM_00320 3.7e-82 usp6 T universal stress protein
CIMHLLIM_00321 4.4e-46
CIMHLLIM_00322 1.8e-240 rarA L recombination factor protein RarA
CIMHLLIM_00323 1.8e-84 yueI S Protein of unknown function (DUF1694)
CIMHLLIM_00324 4.7e-21
CIMHLLIM_00328 3.5e-97 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CIMHLLIM_00329 5.6e-48 XK27_01125 L PFAM IS66 Orf2 family protein
CIMHLLIM_00330 8.6e-47 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
CIMHLLIM_00331 1e-23
CIMHLLIM_00332 4.5e-100 V VanZ like family
CIMHLLIM_00333 8.2e-233 cycA E Amino acid permease
CIMHLLIM_00334 2.8e-84 perR P Belongs to the Fur family
CIMHLLIM_00335 4.6e-258 EGP Major facilitator Superfamily
CIMHLLIM_00336 5.1e-93 tag 3.2.2.20 L glycosylase
CIMHLLIM_00337 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIMHLLIM_00338 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIMHLLIM_00339 7.6e-42
CIMHLLIM_00340 1.1e-300 ytgP S Polysaccharide biosynthesis protein
CIMHLLIM_00341 5.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIMHLLIM_00342 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
CIMHLLIM_00343 7.3e-86 uspA T Belongs to the universal stress protein A family
CIMHLLIM_00344 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIMHLLIM_00345 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
CIMHLLIM_00346 2.2e-113
CIMHLLIM_00347 7.4e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
CIMHLLIM_00348 6.8e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIMHLLIM_00349 3.1e-31
CIMHLLIM_00350 2.7e-109 S CAAX protease self-immunity
CIMHLLIM_00351 2.5e-43
CIMHLLIM_00353 8.4e-69
CIMHLLIM_00354 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CIMHLLIM_00355 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
CIMHLLIM_00356 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
CIMHLLIM_00357 4.7e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CIMHLLIM_00358 1.3e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
CIMHLLIM_00359 2.1e-208 folP 2.5.1.15 H dihydropteroate synthase
CIMHLLIM_00360 5.1e-43
CIMHLLIM_00361 1.3e-36
CIMHLLIM_00363 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CIMHLLIM_00364 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CIMHLLIM_00365 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CIMHLLIM_00366 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CIMHLLIM_00367 9.4e-38 yheA S Belongs to the UPF0342 family
CIMHLLIM_00368 2.8e-221 yhaO L Ser Thr phosphatase family protein
CIMHLLIM_00369 0.0 L AAA domain
CIMHLLIM_00370 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CIMHLLIM_00372 1.2e-76 hit FG histidine triad
CIMHLLIM_00373 6.7e-136 ecsA V ABC transporter, ATP-binding protein
CIMHLLIM_00374 3.9e-218 ecsB U ABC transporter
CIMHLLIM_00375 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CIMHLLIM_00376 2.5e-16 S YSIRK type signal peptide
CIMHLLIM_00377 9.5e-16 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
CIMHLLIM_00378 1.3e-12 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
CIMHLLIM_00379 1.3e-64 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
CIMHLLIM_00380 2.6e-11 glsA 3.5.1.2 E Belongs to the glutaminase family
CIMHLLIM_00381 1.1e-56 ytzB S Small secreted protein
CIMHLLIM_00382 1.8e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CIMHLLIM_00383 9.4e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIMHLLIM_00384 1.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CIMHLLIM_00385 1.4e-119 ybhL S Belongs to the BI1 family
CIMHLLIM_00386 2.4e-72 yoaK S Protein of unknown function (DUF1275)
CIMHLLIM_00387 1e-15 yoaK S Protein of unknown function (DUF1275)
CIMHLLIM_00388 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIMHLLIM_00389 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CIMHLLIM_00390 5e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CIMHLLIM_00391 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIMHLLIM_00392 1.9e-221 dnaB L replication initiation and membrane attachment
CIMHLLIM_00393 1.9e-172 dnaI L Primosomal protein DnaI
CIMHLLIM_00394 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CIMHLLIM_00395 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CIMHLLIM_00396 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIMHLLIM_00397 9.9e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
CIMHLLIM_00398 3.3e-103 T Ion transport 2 domain protein
CIMHLLIM_00399 0.0 S Bacterial membrane protein YfhO
CIMHLLIM_00400 1.3e-205 G Transporter, major facilitator family protein
CIMHLLIM_00401 7.1e-109 yvrI K sigma factor activity
CIMHLLIM_00402 6.7e-60 ydiI Q Thioesterase superfamily
CIMHLLIM_00403 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CIMHLLIM_00404 6.3e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CIMHLLIM_00405 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CIMHLLIM_00406 2.8e-31 feoA P FeoA domain
CIMHLLIM_00407 1.9e-144 sufC O FeS assembly ATPase SufC
CIMHLLIM_00408 1.7e-240 sufD O FeS assembly protein SufD
CIMHLLIM_00409 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CIMHLLIM_00410 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
CIMHLLIM_00411 1.2e-271 sufB O assembly protein SufB
CIMHLLIM_00412 8.1e-57 yitW S Iron-sulfur cluster assembly protein
CIMHLLIM_00413 5.2e-159 hipB K Helix-turn-helix
CIMHLLIM_00414 1.3e-114 nreC K PFAM regulatory protein LuxR
CIMHLLIM_00415 9.2e-39 S Cytochrome B5
CIMHLLIM_00416 1e-153 yitU 3.1.3.104 S hydrolase
CIMHLLIM_00417 3.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CIMHLLIM_00418 4.4e-147 f42a O Band 7 protein
CIMHLLIM_00419 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
CIMHLLIM_00420 1.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CIMHLLIM_00421 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
CIMHLLIM_00422 1.5e-186 galR K Periplasmic binding protein-like domain
CIMHLLIM_00423 0.0 rafA 3.2.1.22 G alpha-galactosidase
CIMHLLIM_00424 3.9e-237 L Transposase
CIMHLLIM_00425 3.7e-85 C Flavodoxin
CIMHLLIM_00426 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
CIMHLLIM_00427 3.8e-182 1.1.1.1 C nadph quinone reductase
CIMHLLIM_00428 1.3e-98 M Protein of unknown function (DUF3737)
CIMHLLIM_00429 1.1e-225 4.4.1.8 E Aminotransferase, class I
CIMHLLIM_00430 3.1e-92 S Peptidase propeptide and YPEB domain
CIMHLLIM_00431 4e-224 T GHKL domain
CIMHLLIM_00432 9.9e-118 T Transcriptional regulatory protein, C terminal
CIMHLLIM_00433 3.5e-158 mleP3 S Membrane transport protein
CIMHLLIM_00434 3.9e-237 L Transposase
CIMHLLIM_00435 8.9e-14
CIMHLLIM_00436 7.1e-63
CIMHLLIM_00437 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
CIMHLLIM_00438 2.5e-80 uspA T universal stress protein
CIMHLLIM_00439 0.0 tetP J elongation factor G
CIMHLLIM_00440 8.4e-165 GK ROK family
CIMHLLIM_00441 9.1e-240 brnQ U Component of the transport system for branched-chain amino acids
CIMHLLIM_00442 4.2e-138 aroD S Serine hydrolase (FSH1)
CIMHLLIM_00443 4.6e-80 yagE E amino acid
CIMHLLIM_00444 2.1e-116 yagE E amino acid
CIMHLLIM_00445 2.4e-17 yagE E amino acid
CIMHLLIM_00446 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CIMHLLIM_00447 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
CIMHLLIM_00448 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIMHLLIM_00449 2.6e-269 pipD E Dipeptidase
CIMHLLIM_00450 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
CIMHLLIM_00451 0.0 yfiC V ABC transporter
CIMHLLIM_00452 1.8e-288 lmrA V ABC transporter, ATP-binding protein
CIMHLLIM_00453 1.3e-17 K Winged helix DNA-binding domain
CIMHLLIM_00454 5.5e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIMHLLIM_00455 2.9e-19 S PFAM Archaeal ATPase
CIMHLLIM_00456 1.1e-71 S ECF transporter, substrate-specific component
CIMHLLIM_00457 1.7e-50 S Domain of unknown function (DUF4430)
CIMHLLIM_00458 1.8e-55 cnrT EG PFAM EamA-like transporter family
CIMHLLIM_00459 1.6e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
CIMHLLIM_00460 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CIMHLLIM_00461 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
CIMHLLIM_00462 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CIMHLLIM_00463 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
CIMHLLIM_00464 4.3e-239 hemL 5.4.3.8 H Aminotransferase class-III
CIMHLLIM_00465 6.2e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
CIMHLLIM_00466 9.8e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CIMHLLIM_00467 5.4e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CIMHLLIM_00468 2.7e-58 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
CIMHLLIM_00469 6.6e-239 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
CIMHLLIM_00470 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
CIMHLLIM_00471 6.8e-103 cbiQ P Cobalt transport protein
CIMHLLIM_00472 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CIMHLLIM_00473 8.5e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CIMHLLIM_00474 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
CIMHLLIM_00475 1.1e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
CIMHLLIM_00476 2.7e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
CIMHLLIM_00477 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
CIMHLLIM_00478 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
CIMHLLIM_00479 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
CIMHLLIM_00480 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
CIMHLLIM_00481 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
CIMHLLIM_00482 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
CIMHLLIM_00483 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CIMHLLIM_00484 2.5e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
CIMHLLIM_00485 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CIMHLLIM_00486 8.1e-204 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
CIMHLLIM_00487 1.8e-169 cobD 4.1.1.81 E Aminotransferase class I and II
CIMHLLIM_00488 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
CIMHLLIM_00489 7.9e-117 XK27_04590 S NADPH-dependent FMN reductase
CIMHLLIM_00490 2.9e-73 fld C Flavodoxin
CIMHLLIM_00491 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
CIMHLLIM_00492 5.9e-68 P Cadmium resistance transporter
CIMHLLIM_00493 3.3e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
CIMHLLIM_00494 4.4e-117 3.1.3.48 T Pfam:Y_phosphatase3C
CIMHLLIM_00495 3e-54 pduU E BMC
CIMHLLIM_00496 3.8e-218 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIMHLLIM_00497 4.3e-203 pduQ C Iron-containing alcohol dehydrogenase
CIMHLLIM_00498 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
CIMHLLIM_00499 4.5e-77 pduO S Haem-degrading
CIMHLLIM_00500 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
CIMHLLIM_00501 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
CIMHLLIM_00502 1.3e-79 S Putative propanediol utilisation
CIMHLLIM_00503 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
CIMHLLIM_00504 7.8e-40 pduA_4 CQ BMC
CIMHLLIM_00505 3.6e-57 pduK CQ BMC
CIMHLLIM_00506 4.5e-45 pduH S Dehydratase medium subunit
CIMHLLIM_00507 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
CIMHLLIM_00508 6.2e-72 pduE 4.2.1.28 Q Dehydratase small subunit
CIMHLLIM_00509 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
CIMHLLIM_00510 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
CIMHLLIM_00511 2.7e-134 pduB E BMC
CIMHLLIM_00512 1.6e-37 pduA_4 CQ BMC
CIMHLLIM_00513 8.3e-159 K helix_turn_helix, arabinose operon control protein
CIMHLLIM_00514 3.6e-138 eutJ E Hsp70 protein
CIMHLLIM_00515 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CIMHLLIM_00516 2.2e-160
CIMHLLIM_00517 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
CIMHLLIM_00518 2.6e-160 S AI-2E family transporter
CIMHLLIM_00519 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
CIMHLLIM_00520 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
CIMHLLIM_00521 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
CIMHLLIM_00522 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
CIMHLLIM_00523 1.4e-153 ypdB V (ABC) transporter
CIMHLLIM_00524 3.5e-236 yhdP S Transporter associated domain
CIMHLLIM_00525 2.7e-82 nrdI F Belongs to the NrdI family
CIMHLLIM_00526 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
CIMHLLIM_00527 4.4e-190 yeaN P Transporter, major facilitator family protein
CIMHLLIM_00528 3.2e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CIMHLLIM_00529 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIMHLLIM_00530 2.3e-28
CIMHLLIM_00531 0.0 lacS G Transporter
CIMHLLIM_00532 6.3e-38 ykuJ S Protein of unknown function (DUF1797)
CIMHLLIM_00533 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIMHLLIM_00534 1.5e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
CIMHLLIM_00535 4.6e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CIMHLLIM_00536 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIMHLLIM_00537 2.7e-39 ptsH G phosphocarrier protein HPR
CIMHLLIM_00538 6.4e-27
CIMHLLIM_00539 0.0 clpE O Belongs to the ClpA ClpB family
CIMHLLIM_00540 1.7e-100 S Pfam:DUF3816
CIMHLLIM_00541 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
CIMHLLIM_00542 5.5e-116
CIMHLLIM_00543 4.4e-155 V ABC transporter, ATP-binding protein
CIMHLLIM_00544 6e-64 gntR1 K Transcriptional regulator, GntR family
CIMHLLIM_00545 0.0 bamA GM domain, Protein
CIMHLLIM_00546 0.0 S Peptidase, M23
CIMHLLIM_00547 0.0 M NlpC/P60 family
CIMHLLIM_00548 1.2e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CIMHLLIM_00549 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CIMHLLIM_00550 7.4e-163 yueF S AI-2E family transporter
CIMHLLIM_00551 0.0 csd1 3.5.1.28 G domain, Protein
CIMHLLIM_00552 1.1e-192 V Beta-lactamase
CIMHLLIM_00553 6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CIMHLLIM_00554 1.8e-98 yhiD S MgtC family
CIMHLLIM_00555 7e-54 S GyrI-like small molecule binding domain
CIMHLLIM_00556 3e-125 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
CIMHLLIM_00557 3.8e-183 ybhR V ABC transporter
CIMHLLIM_00558 1.2e-90 K Bacterial regulatory proteins, tetR family
CIMHLLIM_00559 7.3e-110 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
CIMHLLIM_00560 3.2e-50 azlD E Branched-chain amino acid transport
CIMHLLIM_00561 5.3e-119 azlC E azaleucine resistance protein AzlC
CIMHLLIM_00562 6.9e-259 K Aminotransferase class I and II
CIMHLLIM_00563 2.9e-99 S amidohydrolase
CIMHLLIM_00564 2.8e-79 S amidohydrolase
CIMHLLIM_00565 5.5e-105 L hmm pf00665
CIMHLLIM_00566 2.1e-37 L PFAM Integrase catalytic region
CIMHLLIM_00567 3.3e-121 L PFAM Integrase catalytic region
CIMHLLIM_00568 9.2e-49 2.3.1.183 M Acetyltransferase GNAT family
CIMHLLIM_00569 2.5e-14 2.3.1.183 M Acetyltransferase GNAT family
CIMHLLIM_00570 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CIMHLLIM_00571 1.4e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
CIMHLLIM_00572 1.7e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIMHLLIM_00573 0.0 asnB 6.3.5.4 E Asparagine synthase
CIMHLLIM_00574 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CIMHLLIM_00575 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CIMHLLIM_00576 1.1e-130 jag S R3H domain protein
CIMHLLIM_00577 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIMHLLIM_00578 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CIMHLLIM_00579 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
CIMHLLIM_00580 1.1e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIMHLLIM_00581 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CIMHLLIM_00582 4.9e-34 yaaA S S4 domain protein YaaA
CIMHLLIM_00583 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIMHLLIM_00584 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIMHLLIM_00585 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIMHLLIM_00586 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
CIMHLLIM_00587 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CIMHLLIM_00588 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CIMHLLIM_00589 1.3e-75 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CIMHLLIM_00590 6.5e-18 deoR K sugar-binding domain protein
CIMHLLIM_00591 1.1e-52 deoR K sugar-binding domain protein
CIMHLLIM_00592 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CIMHLLIM_00593 2e-74 rplI J Binds to the 23S rRNA
CIMHLLIM_00594 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CIMHLLIM_00595 2.6e-206 yttB EGP Major facilitator Superfamily
CIMHLLIM_00596 9.1e-61
CIMHLLIM_00597 1.4e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
CIMHLLIM_00598 3.8e-38 Z012_01130 S Fic/DOC family
CIMHLLIM_00599 3e-71 Z012_01130 S Fic/DOC family
CIMHLLIM_00601 1.8e-72 K helix_turn_helix multiple antibiotic resistance protein
CIMHLLIM_00602 2.9e-307 lmrA 3.6.3.44 V ABC transporter
CIMHLLIM_00604 3.1e-130 K response regulator
CIMHLLIM_00605 0.0 vicK 2.7.13.3 T Histidine kinase
CIMHLLIM_00606 2e-244 yycH S YycH protein
CIMHLLIM_00607 7.8e-149 yycI S YycH protein
CIMHLLIM_00608 5.9e-154 vicX 3.1.26.11 S domain protein
CIMHLLIM_00609 6.6e-216 htrA 3.4.21.107 O serine protease
CIMHLLIM_00610 1e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
CIMHLLIM_00611 1.5e-175 ABC-SBP S ABC transporter
CIMHLLIM_00612 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CIMHLLIM_00614 2.9e-96 S reductase
CIMHLLIM_00615 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
CIMHLLIM_00616 1.3e-154 glcU U sugar transport
CIMHLLIM_00617 1.9e-149 E Glyoxalase-like domain
CIMHLLIM_00618 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIMHLLIM_00619 4.4e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
CIMHLLIM_00620 2.8e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CIMHLLIM_00621 2.8e-128 V ABC transporter
CIMHLLIM_00622 7.8e-214 bacI V MacB-like periplasmic core domain
CIMHLLIM_00623 3.8e-22
CIMHLLIM_00624 4.8e-260 S Putative peptidoglycan binding domain
CIMHLLIM_00626 1.6e-08 2.7.13.3 T GHKL domain
CIMHLLIM_00627 8.7e-54 L An automated process has identified a potential problem with this gene model
CIMHLLIM_00628 3.6e-85 K FR47-like protein
CIMHLLIM_00629 4e-119 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
CIMHLLIM_00632 5e-75 osmC O OsmC-like protein
CIMHLLIM_00633 8.3e-174 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIMHLLIM_00634 1.8e-215 patA 2.6.1.1 E Aminotransferase
CIMHLLIM_00635 7.8e-32
CIMHLLIM_00636 0.0 clpL O associated with various cellular activities
CIMHLLIM_00638 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
CIMHLLIM_00639 5.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIMHLLIM_00640 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CIMHLLIM_00641 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CIMHLLIM_00642 4.3e-172 malR K Transcriptional regulator, LacI family
CIMHLLIM_00643 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
CIMHLLIM_00644 1.1e-256 malT G Major Facilitator
CIMHLLIM_00645 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
CIMHLLIM_00646 1.6e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
CIMHLLIM_00647 1e-71
CIMHLLIM_00648 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
CIMHLLIM_00649 3.3e-118 K response regulator
CIMHLLIM_00650 3.1e-226 sptS 2.7.13.3 T Histidine kinase
CIMHLLIM_00651 4.7e-216 yfeO P Voltage gated chloride channel
CIMHLLIM_00652 5.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CIMHLLIM_00653 8.6e-136 puuD S peptidase C26
CIMHLLIM_00654 5.9e-168 yvgN C Aldo keto reductase
CIMHLLIM_00655 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
CIMHLLIM_00656 1.5e-86 hmpT S ECF-type riboflavin transporter, S component
CIMHLLIM_00657 2e-263 nox C NADH oxidase
CIMHLLIM_00658 3.8e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIMHLLIM_00659 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIMHLLIM_00660 3.9e-78
CIMHLLIM_00661 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CIMHLLIM_00663 9.3e-13 steT_1 E amino acid
CIMHLLIM_00664 4.3e-13 K Transcriptional regulator, TetR family
CIMHLLIM_00665 1e-73 K Transcriptional regulator, TetR family
CIMHLLIM_00666 8.3e-72
CIMHLLIM_00667 3.1e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
CIMHLLIM_00668 1.4e-270 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
CIMHLLIM_00669 3e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
CIMHLLIM_00670 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
CIMHLLIM_00671 7.5e-266 G Major Facilitator
CIMHLLIM_00672 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CIMHLLIM_00673 1.1e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CIMHLLIM_00674 6.1e-260 G Major Facilitator
CIMHLLIM_00675 8.9e-176 K Transcriptional regulator, LacI family
CIMHLLIM_00676 7.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIMHLLIM_00677 5.4e-101 nqr 1.5.1.36 S reductase
CIMHLLIM_00678 1.2e-198 XK27_09615 S reductase
CIMHLLIM_00679 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CIMHLLIM_00680 1.3e-72 L PFAM Integrase catalytic region
CIMHLLIM_00681 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIMHLLIM_00682 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CIMHLLIM_00683 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
CIMHLLIM_00684 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIMHLLIM_00685 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CIMHLLIM_00686 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
CIMHLLIM_00687 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
CIMHLLIM_00688 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CIMHLLIM_00689 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CIMHLLIM_00690 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
CIMHLLIM_00691 7.2e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CIMHLLIM_00692 1.8e-121 radC L DNA repair protein
CIMHLLIM_00693 1.7e-179 mreB D cell shape determining protein MreB
CIMHLLIM_00694 3.5e-152 mreC M Involved in formation and maintenance of cell shape
CIMHLLIM_00695 8.7e-93 mreD M rod shape-determining protein MreD
CIMHLLIM_00696 3.2e-102 glnP P ABC transporter permease
CIMHLLIM_00697 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIMHLLIM_00698 2.5e-158 aatB ET ABC transporter substrate-binding protein
CIMHLLIM_00699 5.3e-226 ymfF S Peptidase M16 inactive domain protein
CIMHLLIM_00700 2.3e-248 ymfH S Peptidase M16
CIMHLLIM_00701 1.2e-135 ymfM S Helix-turn-helix domain
CIMHLLIM_00702 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIMHLLIM_00703 8.1e-227 cinA 3.5.1.42 S Belongs to the CinA family
CIMHLLIM_00704 1.7e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIMHLLIM_00705 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
CIMHLLIM_00706 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CIMHLLIM_00707 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CIMHLLIM_00708 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CIMHLLIM_00709 1.3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CIMHLLIM_00710 1.7e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CIMHLLIM_00711 6.2e-31 yajC U Preprotein translocase
CIMHLLIM_00712 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
CIMHLLIM_00713 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CIMHLLIM_00714 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CIMHLLIM_00715 4.1e-43 yrzL S Belongs to the UPF0297 family
CIMHLLIM_00716 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIMHLLIM_00717 6.1e-48 yrzB S Belongs to the UPF0473 family
CIMHLLIM_00718 2.7e-86 cvpA S Colicin V production protein
CIMHLLIM_00719 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CIMHLLIM_00720 6.1e-54 trxA O Belongs to the thioredoxin family
CIMHLLIM_00721 3e-96 yslB S Protein of unknown function (DUF2507)
CIMHLLIM_00722 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CIMHLLIM_00723 3.7e-105 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CIMHLLIM_00724 1.7e-93 S Phosphoesterase
CIMHLLIM_00725 1.1e-74 ykuL S (CBS) domain
CIMHLLIM_00726 1.8e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
CIMHLLIM_00727 3.4e-147 ykuT M mechanosensitive ion channel
CIMHLLIM_00728 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CIMHLLIM_00729 3e-25
CIMHLLIM_00730 3.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CIMHLLIM_00731 7.1e-181 ccpA K catabolite control protein A
CIMHLLIM_00732 3.3e-131
CIMHLLIM_00733 5.9e-132 yebC K Transcriptional regulatory protein
CIMHLLIM_00734 4.9e-179 comGA NU Type II IV secretion system protein
CIMHLLIM_00735 5.1e-182 comGB NU type II secretion system
CIMHLLIM_00736 7.1e-47 comGC U competence protein ComGC
CIMHLLIM_00737 3.4e-79 NU general secretion pathway protein
CIMHLLIM_00738 3.2e-41
CIMHLLIM_00739 1.2e-68
CIMHLLIM_00741 7.9e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
CIMHLLIM_00742 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIMHLLIM_00743 4.7e-111 S Calcineurin-like phosphoesterase
CIMHLLIM_00744 6.6e-93 yutD S Protein of unknown function (DUF1027)
CIMHLLIM_00745 5.5e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CIMHLLIM_00746 2.8e-101 S Protein of unknown function (DUF1461)
CIMHLLIM_00747 1.6e-109 dedA S SNARE-like domain protein
CIMHLLIM_00748 1.6e-54 S Short repeat of unknown function (DUF308)
CIMHLLIM_00749 2.5e-77 S Psort location Cytoplasmic, score
CIMHLLIM_00750 4.6e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
CIMHLLIM_00751 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
CIMHLLIM_00752 4.5e-152 yeaE S Aldo keto
CIMHLLIM_00753 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
CIMHLLIM_00754 4.7e-235 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
CIMHLLIM_00755 1.5e-146 xth 3.1.11.2 L exodeoxyribonuclease III
CIMHLLIM_00756 1.3e-88 lytE M LysM domain protein
CIMHLLIM_00757 0.0 oppD EP Psort location Cytoplasmic, score
CIMHLLIM_00758 2e-42 lytE M LysM domain protein
CIMHLLIM_00759 9.8e-158 sufD O Uncharacterized protein family (UPF0051)
CIMHLLIM_00760 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CIMHLLIM_00761 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CIMHLLIM_00762 1.1e-57 lmrB EGP Major facilitator Superfamily
CIMHLLIM_00763 2.2e-152 lmrB EGP Major facilitator Superfamily
CIMHLLIM_00764 4.1e-98 2.3.1.128 K Acetyltransferase (GNAT) domain
CIMHLLIM_00765 6.8e-154 M Glycosyl hydrolases family 25
CIMHLLIM_00766 5.2e-57 S Bacteriophage holin of superfamily 6 (Holin_LLH)
CIMHLLIM_00767 8.4e-34
CIMHLLIM_00768 4.3e-131 E GDSL-like Lipase/Acylhydrolase
CIMHLLIM_00770 0.0 M Prophage endopeptidase tail
CIMHLLIM_00771 8.9e-147 S phage tail
CIMHLLIM_00772 2.6e-259 sca1 D Phage tail tape measure protein
CIMHLLIM_00773 1e-60
CIMHLLIM_00774 2.6e-55 S Phage tail assembly chaperone protein, TAC
CIMHLLIM_00775 7.7e-103 S Phage tail tube protein
CIMHLLIM_00776 8.4e-21 S Protein of unknown function (DUF3168)
CIMHLLIM_00777 4.2e-68 S Bacteriophage HK97-gp10, putative tail-component
CIMHLLIM_00778 7.9e-46
CIMHLLIM_00779 2.1e-64 S Phage gp6-like head-tail connector protein
CIMHLLIM_00780 1.1e-153
CIMHLLIM_00781 2.6e-101 S Domain of unknown function (DUF4355)
CIMHLLIM_00783 2e-173 S Phage Mu protein F like protein
CIMHLLIM_00784 3.3e-272 S Phage portal protein
CIMHLLIM_00785 1.1e-244 S Phage terminase, large subunit
CIMHLLIM_00787 1.6e-60 L Terminase small subunit
CIMHLLIM_00789 4.7e-79 arpU S Phage transcriptional regulator, ArpU family
CIMHLLIM_00796 8e-60 S VRR_NUC
CIMHLLIM_00798 2.6e-233 S Virulence-associated protein E
CIMHLLIM_00799 1.9e-136 S Bifunctional DNA primase/polymerase, N-terminal
CIMHLLIM_00800 1.7e-93
CIMHLLIM_00801 7.1e-141 L AAA domain
CIMHLLIM_00802 4e-259 res L Helicase C-terminal domain protein
CIMHLLIM_00803 2.7e-77 S Siphovirus Gp157
CIMHLLIM_00804 1.2e-29
CIMHLLIM_00806 8.8e-40
CIMHLLIM_00808 6e-15 XK27_10050 K Peptidase S24-like
CIMHLLIM_00809 2.4e-19 E Zn peptidase
CIMHLLIM_00810 9.7e-69
CIMHLLIM_00811 2.7e-26 S Domain of unknown function (DUF4352)
CIMHLLIM_00812 8.6e-143 L Belongs to the 'phage' integrase family
CIMHLLIM_00822 2.4e-178 ycsG P Natural resistance-associated macrophage protein
CIMHLLIM_00823 5.8e-103 ycsF S LamB/YcsF family
CIMHLLIM_00824 3.5e-207 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
CIMHLLIM_00825 3.8e-38 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CIMHLLIM_00826 1.1e-107 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
CIMHLLIM_00827 7.7e-84 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
CIMHLLIM_00828 2.2e-41 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CIMHLLIM_00830 6.2e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CIMHLLIM_00831 3.3e-110 tesE Q hydratase
CIMHLLIM_00832 5.3e-64 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CIMHLLIM_00833 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CIMHLLIM_00834 1.6e-296 mco Q Multicopper oxidase
CIMHLLIM_00835 1.7e-127 L PFAM Integrase catalytic region
CIMHLLIM_00836 8.7e-113 fic S Fic/DOC family
CIMHLLIM_00837 2e-129 L Belongs to the 'phage' integrase family
CIMHLLIM_00838 4e-19
CIMHLLIM_00841 2.2e-153
CIMHLLIM_00843 1.6e-76 L Resolvase, N terminal domain
CIMHLLIM_00844 3.8e-10 L Resolvase, N terminal domain
CIMHLLIM_00845 2.8e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CIMHLLIM_00849 6.3e-238 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIMHLLIM_00850 3.5e-49 czrA K Transcriptional regulator, ArsR family
CIMHLLIM_00851 2.5e-36
CIMHLLIM_00852 0.0 yhcA V ABC transporter, ATP-binding protein
CIMHLLIM_00853 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
CIMHLLIM_00854 2.1e-167 hrtB V ABC transporter permease
CIMHLLIM_00855 1.8e-84 ygfC K transcriptional regulator (TetR family)
CIMHLLIM_00856 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
CIMHLLIM_00857 1.2e-286 mntH P H( )-stimulated, divalent metal cation uptake system
CIMHLLIM_00858 3.9e-237 L Transposase
CIMHLLIM_00859 6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CIMHLLIM_00860 8.3e-21
CIMHLLIM_00861 6e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
CIMHLLIM_00862 1.4e-167 L transposase, IS605 OrfB family
CIMHLLIM_00863 1e-295 L PFAM plasmid pRiA4b ORF-3 family protein
CIMHLLIM_00864 3.3e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
CIMHLLIM_00865 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIMHLLIM_00866 4.3e-158 mleR K LysR family
CIMHLLIM_00867 1.2e-302 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
CIMHLLIM_00868 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CIMHLLIM_00869 5.8e-266 frdC 1.3.5.4 C FAD binding domain
CIMHLLIM_00870 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
CIMHLLIM_00871 3.9e-237 L Transposase
CIMHLLIM_00872 2.8e-188 L Transposase IS66 family
CIMHLLIM_00873 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
CIMHLLIM_00874 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CIMHLLIM_00875 1.4e-47 gcvH E glycine cleavage
CIMHLLIM_00876 1.1e-220 rodA D Belongs to the SEDS family
CIMHLLIM_00877 1e-31 S Protein of unknown function (DUF2969)
CIMHLLIM_00878 1.9e-178 mbl D Cell shape determining protein MreB Mrl
CIMHLLIM_00879 3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIMHLLIM_00880 1.3e-33 ywzB S Protein of unknown function (DUF1146)
CIMHLLIM_00881 3.8e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CIMHLLIM_00882 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIMHLLIM_00883 4.8e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIMHLLIM_00884 4.4e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIMHLLIM_00885 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIMHLLIM_00886 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIMHLLIM_00887 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIMHLLIM_00888 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
CIMHLLIM_00889 7.7e-233 pyrP F Permease
CIMHLLIM_00890 4.4e-130 yibF S overlaps another CDS with the same product name
CIMHLLIM_00891 2.9e-191 yibE S overlaps another CDS with the same product name
CIMHLLIM_00892 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIMHLLIM_00893 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CIMHLLIM_00894 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIMHLLIM_00895 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CIMHLLIM_00896 1.5e-166 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CIMHLLIM_00897 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CIMHLLIM_00898 1.7e-107 tdk 2.7.1.21 F thymidine kinase
CIMHLLIM_00899 2.2e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
CIMHLLIM_00900 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
CIMHLLIM_00901 3e-10
CIMHLLIM_00902 6.1e-223 arcD U Amino acid permease
CIMHLLIM_00903 1.1e-259 E Arginine ornithine antiporter
CIMHLLIM_00904 2.7e-79 argR K Regulates arginine biosynthesis genes
CIMHLLIM_00905 2e-217 arcA 3.5.3.6 E Arginine
CIMHLLIM_00906 1.5e-183 ampC V Beta-lactamase
CIMHLLIM_00907 7e-19
CIMHLLIM_00908 0.0 M domain protein
CIMHLLIM_00909 9.7e-139 M domain protein
CIMHLLIM_00910 3.8e-90
CIMHLLIM_00911 7e-134 L Belongs to the 'phage' integrase family
CIMHLLIM_00912 2e-08 xre K sequence-specific DNA binding
CIMHLLIM_00913 2.6e-12
CIMHLLIM_00914 1.5e-29
CIMHLLIM_00915 1.8e-39 K COG3617 Prophage antirepressor
CIMHLLIM_00917 5e-08
CIMHLLIM_00921 8.9e-09 L DnaD domain protein
CIMHLLIM_00923 5.5e-68
CIMHLLIM_00926 4.6e-53
CIMHLLIM_00929 1.4e-47 yjcE P Sodium proton antiporter
CIMHLLIM_00930 5.9e-117 yjcE P Sodium proton antiporter
CIMHLLIM_00931 3.9e-40 yjcE P Sodium proton antiporter
CIMHLLIM_00932 2.3e-56
CIMHLLIM_00934 1.2e-85
CIMHLLIM_00935 0.0 copA 3.6.3.54 P P-type ATPase
CIMHLLIM_00936 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CIMHLLIM_00937 1.4e-101 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
CIMHLLIM_00939 1e-11 S by MetaGeneAnnotator
CIMHLLIM_00943 5.2e-41 S Domain of unknown function (DUF2479)
CIMHLLIM_00946 6e-218 M CHAP domain
CIMHLLIM_00947 1.9e-81 S Phage tail protein
CIMHLLIM_00948 5.2e-131 Z012_10445 D Phage tail tape measure protein
CIMHLLIM_00949 8.2e-14
CIMHLLIM_00951 1e-11 S by MetaGeneAnnotator
CIMHLLIM_00955 5.2e-41 S Domain of unknown function (DUF2479)
CIMHLLIM_00958 1.5e-224 M CHAP domain
CIMHLLIM_00959 1.4e-90 S Phage tail protein
CIMHLLIM_00960 1.8e-134 Z012_10445 D Phage tail tape measure protein
CIMHLLIM_00961 1.1e-13
CIMHLLIM_00962 9.9e-21 M CHAP domain
CIMHLLIM_00965 5.2e-41 S Domain of unknown function (DUF2479)
CIMHLLIM_00969 1e-11 S by MetaGeneAnnotator
CIMHLLIM_00971 1.3e-31
CIMHLLIM_00972 2.2e-24 S Bacteriophage holin of superfamily 6 (Holin_LLH)
CIMHLLIM_00973 1.7e-183 ps461 3.5.1.104 M hydrolase, family 25
CIMHLLIM_00974 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIMHLLIM_00975 1.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
CIMHLLIM_00976 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CIMHLLIM_00977 9.9e-21 M CHAP domain
CIMHLLIM_00980 5.2e-41 S Domain of unknown function (DUF2479)
CIMHLLIM_00984 1e-11 S by MetaGeneAnnotator
CIMHLLIM_00986 1.3e-31
CIMHLLIM_00987 2.6e-45 S Bacteriophage holin of superfamily 6 (Holin_LLH)
CIMHLLIM_00988 2.2e-176 M Glycosyl hydrolases family 25
CIMHLLIM_00989 1.9e-11 T PFAM SpoVT AbrB
CIMHLLIM_00990 2.7e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIMHLLIM_00991 7.8e-16 gntT EG Gluconate
CIMHLLIM_00992 1.7e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
CIMHLLIM_00993 2.9e-96 K Acetyltransferase (GNAT) domain
CIMHLLIM_00994 2.4e-22
CIMHLLIM_00995 2.2e-44
CIMHLLIM_00996 3.1e-57 yhaI S Protein of unknown function (DUF805)
CIMHLLIM_00997 6.2e-140 IQ reductase
CIMHLLIM_00998 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
CIMHLLIM_00999 1e-280 hsdM 2.1.1.72 V type I restriction-modification system
CIMHLLIM_01000 2.6e-47 3.1.21.3 V Type I restriction modification DNA specificity domain
CIMHLLIM_01001 8.9e-178 L Belongs to the 'phage' integrase family
CIMHLLIM_01002 5.5e-57 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
CIMHLLIM_01003 3.3e-161 L restriction endonuclease
CIMHLLIM_01004 2e-89 mrr L restriction endonuclease
CIMHLLIM_01005 0.0 L PLD-like domain
CIMHLLIM_01007 8.2e-67 ywiB S Domain of unknown function (DUF1934)
CIMHLLIM_01008 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CIMHLLIM_01009 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CIMHLLIM_01010 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIMHLLIM_01011 4.6e-41 rpmE2 J Ribosomal protein L31
CIMHLLIM_01012 4.5e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIMHLLIM_01013 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
CIMHLLIM_01014 7.3e-116 srtA 3.4.22.70 M sortase family
CIMHLLIM_01015 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CIMHLLIM_01016 2.3e-158 3.2.1.55 GH51 G Right handed beta helix region
CIMHLLIM_01017 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIMHLLIM_01018 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
CIMHLLIM_01019 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
CIMHLLIM_01020 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIMHLLIM_01021 7e-93 lemA S LemA family
CIMHLLIM_01022 2e-158 htpX O Belongs to the peptidase M48B family
CIMHLLIM_01023 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CIMHLLIM_01024 8.7e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CIMHLLIM_01025 4.9e-160 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIMHLLIM_01026 3.4e-121 L Helix-turn-helix domain
CIMHLLIM_01027 7.9e-123 O Zinc-dependent metalloprotease
CIMHLLIM_01028 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CIMHLLIM_01029 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
CIMHLLIM_01032 4.9e-80 KT Purine catabolism regulatory protein-like family
CIMHLLIM_01033 5.5e-154 F Permease for cytosine/purines, uracil, thiamine, allantoin
CIMHLLIM_01034 5.2e-153 S Protein of unknown function (DUF917)
CIMHLLIM_01035 1.8e-183 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
CIMHLLIM_01036 2.7e-236 G MFS/sugar transport protein
CIMHLLIM_01037 5.9e-11
CIMHLLIM_01040 1.6e-85 S MobA/MobL family
CIMHLLIM_01044 1.1e-113 S (CBS) domain
CIMHLLIM_01045 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CIMHLLIM_01046 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIMHLLIM_01047 2.1e-39 yabO J S4 domain protein
CIMHLLIM_01048 5.6e-56 divIC D Septum formation initiator
CIMHLLIM_01049 9.8e-67 yabR J RNA binding
CIMHLLIM_01050 1.2e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CIMHLLIM_01051 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CIMHLLIM_01052 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIMHLLIM_01053 2.6e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CIMHLLIM_01054 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIMHLLIM_01055 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CIMHLLIM_01056 5.6e-84
CIMHLLIM_01057 3.8e-85 yxjG_1 E methionine synthase, vitamin-B12 independent
CIMHLLIM_01058 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
CIMHLLIM_01059 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CIMHLLIM_01060 8e-134 D nuclear chromosome segregation
CIMHLLIM_01061 0.0 lacZ 3.2.1.23 G -beta-galactosidase
CIMHLLIM_01062 0.0 lacS G Transporter
CIMHLLIM_01063 3e-187 lacR K Transcriptional regulator
CIMHLLIM_01064 3.8e-10
CIMHLLIM_01065 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
CIMHLLIM_01066 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
CIMHLLIM_01067 8.5e-34
CIMHLLIM_01068 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CIMHLLIM_01069 9.9e-261 yfnA E amino acid
CIMHLLIM_01070 2.2e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CIMHLLIM_01071 7.6e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIMHLLIM_01072 4.1e-40 ylqC S Belongs to the UPF0109 family
CIMHLLIM_01073 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CIMHLLIM_01074 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIMHLLIM_01075 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CIMHLLIM_01076 1.1e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CIMHLLIM_01077 0.0 smc D Required for chromosome condensation and partitioning
CIMHLLIM_01078 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CIMHLLIM_01079 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIMHLLIM_01080 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CIMHLLIM_01081 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CIMHLLIM_01082 0.0 yloV S DAK2 domain fusion protein YloV
CIMHLLIM_01083 4.7e-58 asp S Asp23 family, cell envelope-related function
CIMHLLIM_01084 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CIMHLLIM_01085 2.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
CIMHLLIM_01086 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CIMHLLIM_01087 1.5e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CIMHLLIM_01088 0.0 KLT serine threonine protein kinase
CIMHLLIM_01089 6.1e-129 stp 3.1.3.16 T phosphatase
CIMHLLIM_01090 2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CIMHLLIM_01091 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIMHLLIM_01092 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CIMHLLIM_01093 1.3e-208 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CIMHLLIM_01094 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CIMHLLIM_01095 7.9e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CIMHLLIM_01096 4.2e-53
CIMHLLIM_01097 6.1e-262 recN L May be involved in recombinational repair of damaged DNA
CIMHLLIM_01098 7.3e-77 argR K Regulates arginine biosynthesis genes
CIMHLLIM_01099 1.2e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CIMHLLIM_01100 4.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CIMHLLIM_01101 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIMHLLIM_01102 2.6e-215 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIMHLLIM_01103 1.3e-146 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CIMHLLIM_01104 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIMHLLIM_01105 2.2e-70 yqhY S Asp23 family, cell envelope-related function
CIMHLLIM_01106 1.7e-114 J 2'-5' RNA ligase superfamily
CIMHLLIM_01107 7.3e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CIMHLLIM_01108 2.6e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CIMHLLIM_01109 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CIMHLLIM_01110 2.4e-53 ysxB J Cysteine protease Prp
CIMHLLIM_01111 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
CIMHLLIM_01112 7e-110 K Transcriptional regulator
CIMHLLIM_01115 5.7e-86 dut S Protein conserved in bacteria
CIMHLLIM_01116 3e-179
CIMHLLIM_01117 9.7e-150
CIMHLLIM_01118 4.8e-51 S Iron-sulfur cluster assembly protein
CIMHLLIM_01119 4.7e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIMHLLIM_01120 3.9e-12
CIMHLLIM_01121 2.3e-41 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
CIMHLLIM_01122 6.1e-32 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
CIMHLLIM_01123 3.9e-96 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
CIMHLLIM_01124 2.2e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIMHLLIM_01125 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
CIMHLLIM_01126 2e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIMHLLIM_01127 5.9e-22 S Protein of unknown function (DUF3042)
CIMHLLIM_01128 3.4e-67 yqhL P Rhodanese-like protein
CIMHLLIM_01129 5.6e-183 glk 2.7.1.2 G Glucokinase
CIMHLLIM_01130 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
CIMHLLIM_01131 1.6e-19 gluP 3.4.21.105 S Peptidase, S54 family
CIMHLLIM_01132 1.6e-74 gluP 3.4.21.105 S Peptidase, S54 family
CIMHLLIM_01133 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CIMHLLIM_01134 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CIMHLLIM_01135 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
CIMHLLIM_01136 0.0 S membrane
CIMHLLIM_01137 3.1e-68 yneR S Belongs to the HesB IscA family
CIMHLLIM_01138 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIMHLLIM_01139 2.3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
CIMHLLIM_01140 3.6e-114 rlpA M PFAM NLP P60 protein
CIMHLLIM_01141 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIMHLLIM_01142 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CIMHLLIM_01143 4.4e-58 yodB K Transcriptional regulator, HxlR family
CIMHLLIM_01144 1.2e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
CIMHLLIM_01145 4.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIMHLLIM_01146 1.6e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CIMHLLIM_01147 1.3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIMHLLIM_01148 8.2e-67 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CIMHLLIM_01149 4.3e-234 V MatE
CIMHLLIM_01150 4.8e-266 yjeM E Amino Acid
CIMHLLIM_01151 3.7e-279 arlS 2.7.13.3 T Histidine kinase
CIMHLLIM_01152 1.5e-121 K response regulator
CIMHLLIM_01153 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CIMHLLIM_01154 2.9e-99 yceD S Uncharacterized ACR, COG1399
CIMHLLIM_01155 1.5e-208 ylbM S Belongs to the UPF0348 family
CIMHLLIM_01156 1.1e-135 yqeM Q Methyltransferase
CIMHLLIM_01157 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CIMHLLIM_01158 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
CIMHLLIM_01159 6.9e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIMHLLIM_01160 1.9e-47 yhbY J RNA-binding protein
CIMHLLIM_01161 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
CIMHLLIM_01162 1.4e-95 yqeG S HAD phosphatase, family IIIA
CIMHLLIM_01163 0.0 tetP J elongation factor G
CIMHLLIM_01164 3e-69 S Conjugative transposon protein TcpC
CIMHLLIM_01167 5.2e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
CIMHLLIM_01168 8.3e-34
CIMHLLIM_01169 3.6e-07 L Resolvase, N terminal domain
CIMHLLIM_01170 1.9e-185 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
CIMHLLIM_01171 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
CIMHLLIM_01172 1.6e-42 hxlR K Transcriptional regulator, HxlR family
CIMHLLIM_01173 7.5e-162 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
CIMHLLIM_01174 2.4e-71 K Helix-turn-helix domain
CIMHLLIM_01176 6e-93 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
CIMHLLIM_01177 3.7e-31 S Protein of unknown function (DUF2089)
CIMHLLIM_01178 9.3e-28
CIMHLLIM_01181 5.7e-90 L Integrase
CIMHLLIM_01183 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
CIMHLLIM_01184 1.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIMHLLIM_01185 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
CIMHLLIM_01186 3.1e-113 yjbH Q Thioredoxin
CIMHLLIM_01187 1.4e-267 pipD E Dipeptidase
CIMHLLIM_01188 2.6e-194 coiA 3.6.4.12 S Competence protein
CIMHLLIM_01189 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CIMHLLIM_01190 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CIMHLLIM_01191 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CIMHLLIM_01192 6.7e-173 scrR K Transcriptional regulator, LacI family
CIMHLLIM_01193 1e-24
CIMHLLIM_01194 1e-100
CIMHLLIM_01195 4.9e-213 yttB EGP Major facilitator Superfamily
CIMHLLIM_01196 1.5e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
CIMHLLIM_01197 3.6e-85
CIMHLLIM_01198 1.5e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
CIMHLLIM_01199 1.4e-259 S Putative peptidoglycan binding domain
CIMHLLIM_01200 1.3e-122 yciB M ErfK YbiS YcfS YnhG
CIMHLLIM_01202 4.8e-97
CIMHLLIM_01203 5.3e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CIMHLLIM_01204 1.5e-63 S Alpha beta hydrolase
CIMHLLIM_01205 2.2e-38 S Alpha beta hydrolase
CIMHLLIM_01206 4.5e-82 L transposase IS116 IS110 IS902 family protein
CIMHLLIM_01207 1.8e-113 L transposase IS116 IS110 IS902 family protein
CIMHLLIM_01208 1.1e-206 gldA 1.1.1.6 C dehydrogenase
CIMHLLIM_01209 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIMHLLIM_01210 1.2e-39
CIMHLLIM_01211 2.7e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
CIMHLLIM_01212 4.6e-36 K Bacterial transcriptional regulator
CIMHLLIM_01213 2.9e-70 IQ Enoyl-(Acyl carrier protein) reductase
CIMHLLIM_01214 3.6e-269 S C4-dicarboxylate anaerobic carrier
CIMHLLIM_01215 2.1e-247 nhaC C Na H antiporter NhaC
CIMHLLIM_01216 4.7e-241 pbuX F xanthine permease
CIMHLLIM_01217 1.2e-279 pipD E Dipeptidase
CIMHLLIM_01218 2.8e-168 corA P CorA-like Mg2+ transporter protein
CIMHLLIM_01219 1.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CIMHLLIM_01220 6.6e-131 terC P membrane
CIMHLLIM_01221 3.2e-55 trxA O Belongs to the thioredoxin family
CIMHLLIM_01222 9.5e-234 mepA V MATE efflux family protein
CIMHLLIM_01223 9.9e-55 K Transcriptional regulator, ArsR family
CIMHLLIM_01224 5.1e-96 P Cadmium resistance transporter
CIMHLLIM_01225 1.8e-136 XK27_08845 S ABC transporter, ATP-binding protein
CIMHLLIM_01226 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
CIMHLLIM_01227 4.1e-181 ABC-SBP S ABC transporter
CIMHLLIM_01228 1.7e-73 M PFAM NLP P60 protein
CIMHLLIM_01229 7.4e-104 S Protein of unknown function (DUF3278)
CIMHLLIM_01230 1e-28 WQ51_00220 K Helix-turn-helix domain
CIMHLLIM_01231 3.9e-24 L Integrase
CIMHLLIM_01232 1.1e-13 K Transcriptional
CIMHLLIM_01233 2.8e-95 cadD P Cadmium resistance transporter
CIMHLLIM_01234 9.4e-56 cadX K Bacterial regulatory protein, arsR family
CIMHLLIM_01235 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIMHLLIM_01236 1.6e-180 arsB 1.20.4.1 P Sodium Bile acid symporter family
CIMHLLIM_01237 1.8e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
CIMHLLIM_01238 2.7e-62 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIMHLLIM_01239 4.5e-44 arsB 1.20.4.1 P Sodium Bile acid symporter family
CIMHLLIM_01240 6.4e-18 K Helix-turn-helix domain
CIMHLLIM_01241 2.6e-17 relB L RelB antitoxin
CIMHLLIM_01242 1.9e-273 S ABC transporter, ATP-binding protein
CIMHLLIM_01243 7.8e-143 S Putative ABC-transporter type IV
CIMHLLIM_01244 1.7e-105 NU mannosyl-glycoprotein
CIMHLLIM_01245 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
CIMHLLIM_01246 1.8e-226 S Uncharacterized protein conserved in bacteria (DUF2325)
CIMHLLIM_01247 8.9e-206 nrnB S DHHA1 domain
CIMHLLIM_01248 1.7e-47
CIMHLLIM_01249 1.2e-135 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CIMHLLIM_01250 1.8e-16 S Domain of unknown function (DUF4767)
CIMHLLIM_01251 5.2e-53
CIMHLLIM_01252 3.4e-118 yrkL S Flavodoxin-like fold
CIMHLLIM_01254 5.9e-64 yeaO S Protein of unknown function, DUF488
CIMHLLIM_01255 3.4e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CIMHLLIM_01256 3.4e-203 3.1.3.1 S associated with various cellular activities
CIMHLLIM_01257 4.5e-236 S Putative metallopeptidase domain
CIMHLLIM_01258 1.4e-47
CIMHLLIM_01259 0.0 pepO 3.4.24.71 O Peptidase family M13
CIMHLLIM_01260 4.4e-98 K Helix-turn-helix XRE-family like proteins
CIMHLLIM_01261 4.3e-86 ymdB S Macro domain protein
CIMHLLIM_01262 7.6e-195 EGP Major facilitator Superfamily
CIMHLLIM_01263 2.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIMHLLIM_01264 3.9e-237 L Transposase
CIMHLLIM_01265 3.9e-14 S enterobacterial common antigen metabolic process
CIMHLLIM_01266 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
CIMHLLIM_01267 6.1e-153 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CIMHLLIM_01268 6.4e-30 L PFAM transposase IS200-family protein
CIMHLLIM_01269 1.7e-183 S Phosphotransferase system, EIIC
CIMHLLIM_01270 4.2e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CIMHLLIM_01271 3.9e-182
CIMHLLIM_01272 1.3e-53 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIMHLLIM_01273 8.2e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
CIMHLLIM_01274 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
CIMHLLIM_01275 1.2e-97 2.3.1.128 K acetyltransferase
CIMHLLIM_01276 3.9e-187
CIMHLLIM_01277 2.2e-16 K Transcriptional regulator, HxlR family
CIMHLLIM_01278 3.2e-39 L Transposase
CIMHLLIM_01279 1.3e-145 L Transposase
CIMHLLIM_01280 9.7e-20 L Transposase
CIMHLLIM_01281 3.6e-131 K Transcriptional regulatory protein, C-terminal domain protein
CIMHLLIM_01282 1.1e-158 pstS P Phosphate
CIMHLLIM_01283 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
CIMHLLIM_01284 2.6e-155 pstA P Phosphate transport system permease protein PstA
CIMHLLIM_01285 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIMHLLIM_01286 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
CIMHLLIM_01287 3.3e-142
CIMHLLIM_01288 8.5e-243 ydaM M Glycosyl transferase
CIMHLLIM_01289 1e-223 G Glycosyl hydrolases family 8
CIMHLLIM_01290 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CIMHLLIM_01291 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
CIMHLLIM_01292 4.5e-239 ktrB P Potassium uptake protein
CIMHLLIM_01293 7.7e-115 ktrA P domain protein
CIMHLLIM_01294 1e-77 Q Methyltransferase
CIMHLLIM_01295 1.4e-229 mntH P H( )-stimulated, divalent metal cation uptake system
CIMHLLIM_01296 1.4e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CIMHLLIM_01297 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CIMHLLIM_01298 1.2e-94 S NADPH-dependent FMN reductase
CIMHLLIM_01299 4e-179 MA20_14895 S Conserved hypothetical protein 698
CIMHLLIM_01300 3e-133 I alpha/beta hydrolase fold
CIMHLLIM_01301 2.8e-162 lsa S ABC transporter
CIMHLLIM_01302 3e-27 L PFAM transposase IS200-family protein
CIMHLLIM_01304 6.3e-37 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CIMHLLIM_01305 6.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIMHLLIM_01306 2e-264 glnP P ABC transporter
CIMHLLIM_01307 5.5e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIMHLLIM_01308 1.4e-219 cycA E Amino acid permease
CIMHLLIM_01309 1.3e-218 nupG F Nucleoside transporter
CIMHLLIM_01310 3.3e-169 rihC 3.2.2.1 F Nucleoside
CIMHLLIM_01311 2.7e-160 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
CIMHLLIM_01312 9.2e-122 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
CIMHLLIM_01313 1.8e-144 noc K Belongs to the ParB family
CIMHLLIM_01314 3.6e-140 soj D Sporulation initiation inhibitor
CIMHLLIM_01315 1.9e-153 spo0J K Belongs to the ParB family
CIMHLLIM_01316 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
CIMHLLIM_01317 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CIMHLLIM_01318 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
CIMHLLIM_01319 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CIMHLLIM_01320 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CIMHLLIM_01321 2.1e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
CIMHLLIM_01322 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
CIMHLLIM_01323 1.2e-169 deoR K sugar-binding domain protein
CIMHLLIM_01324 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIMHLLIM_01325 3.8e-125 K response regulator
CIMHLLIM_01326 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
CIMHLLIM_01327 2.3e-138 azlC E AzlC protein
CIMHLLIM_01328 1.6e-52 azlD S branched-chain amino acid
CIMHLLIM_01329 6.6e-124 K LysR substrate binding domain
CIMHLLIM_01330 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CIMHLLIM_01331 2.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CIMHLLIM_01332 3.3e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CIMHLLIM_01333 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CIMHLLIM_01334 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIMHLLIM_01335 1.1e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
CIMHLLIM_01336 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CIMHLLIM_01337 1.8e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CIMHLLIM_01338 6.6e-174 K AI-2E family transporter
CIMHLLIM_01339 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CIMHLLIM_01340 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CIMHLLIM_01341 4.5e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
CIMHLLIM_01342 2.7e-24 K helix_turn_helix, arabinose operon control protein
CIMHLLIM_01343 3.4e-187 thrC 4.2.3.1 E Threonine synthase
CIMHLLIM_01344 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CIMHLLIM_01345 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CIMHLLIM_01346 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CIMHLLIM_01347 1.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CIMHLLIM_01348 8.9e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIMHLLIM_01349 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CIMHLLIM_01350 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIMHLLIM_01351 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIMHLLIM_01352 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIMHLLIM_01353 2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CIMHLLIM_01354 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CIMHLLIM_01355 8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CIMHLLIM_01356 1.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CIMHLLIM_01357 2.8e-243 purD 6.3.4.13 F Belongs to the GARS family
CIMHLLIM_01358 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIMHLLIM_01359 1.8e-166
CIMHLLIM_01360 5.4e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIMHLLIM_01361 6.4e-90 L Transposase IS66 family
CIMHLLIM_01362 2.3e-41 L Transposase IS66 family
CIMHLLIM_01363 9.3e-110 lssY 3.6.1.27 I Acid phosphatase homologues
CIMHLLIM_01364 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
CIMHLLIM_01365 4.4e-129 L PFAM transposase IS116 IS110 IS902
CIMHLLIM_01366 1.3e-227 clcA_2 P Chloride transporter, ClC family
CIMHLLIM_01367 1.5e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CIMHLLIM_01368 1.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CIMHLLIM_01369 8.6e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CIMHLLIM_01370 2e-49
CIMHLLIM_01371 0.0 S SEC-C Motif Domain Protein
CIMHLLIM_01372 2.9e-20
CIMHLLIM_01373 1.8e-43
CIMHLLIM_01374 3.4e-172
CIMHLLIM_01375 6.4e-90 L Transposase IS66 family
CIMHLLIM_01376 5.3e-40 L Transposase IS66 family
CIMHLLIM_01379 1.3e-263 dtpT U amino acid peptide transporter
CIMHLLIM_01380 2.7e-149 yjjH S Calcineurin-like phosphoesterase
CIMHLLIM_01383 1e-111
CIMHLLIM_01384 3.2e-248 EGP Major facilitator Superfamily
CIMHLLIM_01385 1.6e-299 aspT P Predicted Permease Membrane Region
CIMHLLIM_01386 2.4e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CIMHLLIM_01387 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
CIMHLLIM_01388 6.9e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIMHLLIM_01389 4.4e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CIMHLLIM_01390 0.0 yhgF K Tex-like protein N-terminal domain protein
CIMHLLIM_01391 1.5e-82 ydcK S Belongs to the SprT family
CIMHLLIM_01393 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
CIMHLLIM_01394 2.2e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
CIMHLLIM_01395 0.0 S Bacterial membrane protein, YfhO
CIMHLLIM_01396 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIMHLLIM_01397 3.8e-167 I alpha/beta hydrolase fold
CIMHLLIM_01398 2.9e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CIMHLLIM_01399 1.1e-119 tcyB E ABC transporter
CIMHLLIM_01400 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIMHLLIM_01401 4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CIMHLLIM_01402 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
CIMHLLIM_01403 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CIMHLLIM_01404 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
CIMHLLIM_01405 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
CIMHLLIM_01406 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CIMHLLIM_01407 1.1e-204 yacL S domain protein
CIMHLLIM_01408 1.3e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIMHLLIM_01409 4.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CIMHLLIM_01410 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIMHLLIM_01411 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CIMHLLIM_01412 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CIMHLLIM_01413 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
CIMHLLIM_01414 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIMHLLIM_01415 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CIMHLLIM_01416 2.8e-224 aadAT EK Aminotransferase, class I
CIMHLLIM_01418 1.8e-32 M Glycosyl transferase family group 2
CIMHLLIM_01419 6.3e-154 M Glycosyl transferase family group 2
CIMHLLIM_01420 4e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CIMHLLIM_01421 3.8e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIMHLLIM_01422 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CIMHLLIM_01423 4.8e-34
CIMHLLIM_01424 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CIMHLLIM_01425 2.4e-56 K transcriptional regulator PadR family
CIMHLLIM_01426 8.7e-81 XK27_06920 S Protein of unknown function (DUF1700)
CIMHLLIM_01427 3.2e-133 S Putative adhesin
CIMHLLIM_01428 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CIMHLLIM_01429 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIMHLLIM_01430 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIMHLLIM_01431 3.4e-35 nrdH O Glutaredoxin
CIMHLLIM_01432 5.2e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CIMHLLIM_01433 7.6e-290 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIMHLLIM_01434 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CIMHLLIM_01435 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIMHLLIM_01436 1.1e-37 S Protein of unknown function (DUF2508)
CIMHLLIM_01437 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CIMHLLIM_01438 2.9e-51 yaaQ S Cyclic-di-AMP receptor
CIMHLLIM_01439 1.7e-182 holB 2.7.7.7 L DNA polymerase III
CIMHLLIM_01440 3.1e-43 yabA L Involved in initiation control of chromosome replication
CIMHLLIM_01441 7.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CIMHLLIM_01442 8.4e-134 fat 3.1.2.21 I Acyl-ACP thioesterase
CIMHLLIM_01443 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CIMHLLIM_01444 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CIMHLLIM_01445 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CIMHLLIM_01446 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CIMHLLIM_01448 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
CIMHLLIM_01449 9.9e-69 L Transposase IS66 family
CIMHLLIM_01450 4.2e-109 L Bacterial dnaA protein
CIMHLLIM_01451 2.6e-137 L Integrase core domain
CIMHLLIM_01452 2.8e-188 L Transposase IS66 family
CIMHLLIM_01453 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
CIMHLLIM_01455 5e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CIMHLLIM_01456 1.4e-158 rrmA 2.1.1.187 H Methyltransferase
CIMHLLIM_01457 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CIMHLLIM_01458 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CIMHLLIM_01459 1.2e-10 S Protein of unknown function (DUF4044)
CIMHLLIM_01460 1.7e-57
CIMHLLIM_01461 3.1e-77 mraZ K Belongs to the MraZ family
CIMHLLIM_01462 8.8e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CIMHLLIM_01463 2.9e-55 ftsL D Cell division protein FtsL
CIMHLLIM_01464 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CIMHLLIM_01465 4.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIMHLLIM_01466 4.2e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIMHLLIM_01467 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIMHLLIM_01468 2.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CIMHLLIM_01469 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CIMHLLIM_01470 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIMHLLIM_01471 2.1e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CIMHLLIM_01472 3.2e-40 yggT S YGGT family
CIMHLLIM_01473 2.4e-144 ylmH S S4 domain protein
CIMHLLIM_01474 1.3e-35 divIVA D DivIVA domain protein
CIMHLLIM_01475 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIMHLLIM_01476 4.2e-32 cspA K Cold shock protein
CIMHLLIM_01477 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
CIMHLLIM_01479 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIMHLLIM_01480 1.6e-216 iscS 2.8.1.7 E Aminotransferase class V
CIMHLLIM_01481 7.5e-58 XK27_04120 S Putative amino acid metabolism
CIMHLLIM_01482 6.9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CIMHLLIM_01483 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
CIMHLLIM_01484 4.9e-117 S Repeat protein
CIMHLLIM_01485 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CIMHLLIM_01486 6.9e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIMHLLIM_01487 7.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CIMHLLIM_01488 6.7e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
CIMHLLIM_01489 1.5e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CIMHLLIM_01490 7e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CIMHLLIM_01491 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CIMHLLIM_01492 2.9e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIMHLLIM_01493 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CIMHLLIM_01494 7.7e-219 patA 2.6.1.1 E Aminotransferase
CIMHLLIM_01495 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIMHLLIM_01496 8.5e-84 KT Putative sugar diacid recognition
CIMHLLIM_01497 4.2e-218 EG GntP family permease
CIMHLLIM_01498 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CIMHLLIM_01499 2.2e-57
CIMHLLIM_01501 1.7e-122 mltD CBM50 M NlpC P60 family protein
CIMHLLIM_01502 5.7e-29
CIMHLLIM_01503 1.9e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
CIMHLLIM_01504 9.8e-32 ykzG S Belongs to the UPF0356 family
CIMHLLIM_01505 4.8e-79
CIMHLLIM_01506 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIMHLLIM_01507 9.1e-180 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CIMHLLIM_01508 1e-108 mmuP E amino acid
CIMHLLIM_01510 7.4e-67 T Toxin-antitoxin system, toxin component, MazF family
CIMHLLIM_01511 5.2e-37
CIMHLLIM_01512 6.7e-07 D nuclear chromosome segregation
CIMHLLIM_01513 0.0 snf 2.7.11.1 KL domain protein
CIMHLLIM_01514 1e-142 ywqE 3.1.3.48 GM PHP domain protein
CIMHLLIM_01515 6.8e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CIMHLLIM_01516 0.0 sbcC L Putative exonuclease SbcCD, C subunit
CIMHLLIM_01517 6.1e-153 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CIMHLLIM_01518 3.2e-130 O Bacterial dnaA protein
CIMHLLIM_01519 5e-237 L Integrase core domain
CIMHLLIM_01520 1.9e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CIMHLLIM_01521 7.8e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CIMHLLIM_01522 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CIMHLLIM_01523 9.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CIMHLLIM_01524 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIMHLLIM_01525 1.8e-134
CIMHLLIM_01526 1.2e-145 rfbJ M Glycosyl transferase family 2
CIMHLLIM_01527 5.8e-83
CIMHLLIM_01528 2e-72 S Acyltransferase family
CIMHLLIM_01529 1.3e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
CIMHLLIM_01530 1.8e-67 S Glycosyltransferase like family
CIMHLLIM_01531 3.4e-76 rgpB GT2 M Glycosyl transferase family 2
CIMHLLIM_01532 3.9e-28 M biosynthesis protein
CIMHLLIM_01533 3.1e-90 cps3F
CIMHLLIM_01534 4.7e-76 M transferase activity, transferring glycosyl groups
CIMHLLIM_01535 3.2e-211 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
CIMHLLIM_01536 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
CIMHLLIM_01537 6.1e-25
CIMHLLIM_01538 0.0 G Peptidase_C39 like family
CIMHLLIM_01539 1.8e-99 glsA 3.5.1.2 E Belongs to the glutaminase family
CIMHLLIM_01540 4.5e-55 glsA 3.5.1.2 E Belongs to the glutaminase family
CIMHLLIM_01541 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CIMHLLIM_01542 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIMHLLIM_01543 1.1e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
CIMHLLIM_01544 2.2e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIMHLLIM_01546 1.1e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CIMHLLIM_01547 2e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIMHLLIM_01548 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
CIMHLLIM_01549 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
CIMHLLIM_01550 2.3e-242 codA 3.5.4.1 F cytosine deaminase
CIMHLLIM_01551 6.4e-145 tesE Q hydratase
CIMHLLIM_01552 0.0 FbpA K Fibronectin-binding protein
CIMHLLIM_01553 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CIMHLLIM_01554 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
CIMHLLIM_01555 2.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CIMHLLIM_01556 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CIMHLLIM_01557 5.6e-65 esbA S Family of unknown function (DUF5322)
CIMHLLIM_01558 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
CIMHLLIM_01559 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CIMHLLIM_01560 4e-81 F Belongs to the NrdI family
CIMHLLIM_01561 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CIMHLLIM_01562 3.2e-101 ypsA S Belongs to the UPF0398 family
CIMHLLIM_01563 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CIMHLLIM_01564 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
CIMHLLIM_01565 1.3e-160 EG EamA-like transporter family
CIMHLLIM_01566 8.1e-123 dnaD L DnaD domain protein
CIMHLLIM_01567 9.9e-86 ypmB S Protein conserved in bacteria
CIMHLLIM_01568 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CIMHLLIM_01569 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CIMHLLIM_01570 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CIMHLLIM_01571 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CIMHLLIM_01572 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CIMHLLIM_01573 9.3e-86 S Protein of unknown function (DUF1440)
CIMHLLIM_01574 4.1e-159 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIMHLLIM_01575 2.1e-160 degV S EDD domain protein, DegV family
CIMHLLIM_01576 1.1e-89
CIMHLLIM_01577 1.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CIMHLLIM_01578 8.7e-156 gspA M family 8
CIMHLLIM_01579 1.1e-153 S Alpha beta hydrolase
CIMHLLIM_01580 1.5e-94 K Acetyltransferase (GNAT) domain
CIMHLLIM_01581 8.7e-243 XK27_08635 S UPF0210 protein
CIMHLLIM_01582 1.4e-38 gcvR T Belongs to the UPF0237 family
CIMHLLIM_01583 1.7e-170 1.1.1.346 C Aldo keto reductase
CIMHLLIM_01584 1.5e-158 K LysR substrate binding domain protein
CIMHLLIM_01585 2.6e-77 C Flavodoxin
CIMHLLIM_01586 1.5e-77 yphH S Cupin domain
CIMHLLIM_01587 1.7e-73 yeaL S UPF0756 membrane protein
CIMHLLIM_01588 6.2e-244 EGP Major facilitator Superfamily
CIMHLLIM_01589 5e-75 copY K Copper transport repressor CopY TcrY
CIMHLLIM_01590 8.5e-246 yhdP S Transporter associated domain
CIMHLLIM_01591 0.0 ubiB S ABC1 family
CIMHLLIM_01592 1.5e-144 S DUF218 domain
CIMHLLIM_01593 2.1e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIMHLLIM_01594 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIMHLLIM_01595 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIMHLLIM_01596 0.0 uvrA3 L excinuclease ABC, A subunit
CIMHLLIM_01597 3.7e-120 S SNARE associated Golgi protein
CIMHLLIM_01598 2.3e-229 N Uncharacterized conserved protein (DUF2075)
CIMHLLIM_01599 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CIMHLLIM_01601 6.6e-254 yifK E Amino acid permease
CIMHLLIM_01602 7.2e-158 endA V DNA/RNA non-specific endonuclease
CIMHLLIM_01603 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIMHLLIM_01604 2.3e-41 ybaN S Protein of unknown function (DUF454)
CIMHLLIM_01605 1.6e-71 S Protein of unknown function (DUF3290)
CIMHLLIM_01606 4.7e-114 yviA S Protein of unknown function (DUF421)
CIMHLLIM_01607 2.2e-162 S Alpha/beta hydrolase of unknown function (DUF915)
CIMHLLIM_01608 2e-18
CIMHLLIM_01609 2.1e-90 ntd 2.4.2.6 F Nucleoside
CIMHLLIM_01610 3.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
CIMHLLIM_01611 8.9e-41 yrvD S Pfam:DUF1049
CIMHLLIM_01613 3.3e-35 S Phage derived protein Gp49-like (DUF891)
CIMHLLIM_01614 8.5e-20 K Helix-turn-helix XRE-family like proteins
CIMHLLIM_01615 8.8e-164 I alpha/beta hydrolase fold
CIMHLLIM_01616 1e-111 frnE Q DSBA-like thioredoxin domain
CIMHLLIM_01617 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
CIMHLLIM_01618 1e-270 ywfO S HD domain protein
CIMHLLIM_01619 2.1e-146 yxeH S hydrolase
CIMHLLIM_01620 1.2e-47
CIMHLLIM_01621 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIMHLLIM_01622 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIMHLLIM_01623 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CIMHLLIM_01624 1.2e-117 znuB U ABC 3 transport family
CIMHLLIM_01625 2.2e-122 fhuC P ABC transporter
CIMHLLIM_01626 1.8e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
CIMHLLIM_01627 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CIMHLLIM_01628 6.8e-37 veg S Biofilm formation stimulator VEG
CIMHLLIM_01629 3.6e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CIMHLLIM_01630 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CIMHLLIM_01631 3.5e-154 tatD L hydrolase, TatD family
CIMHLLIM_01632 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIMHLLIM_01633 1.2e-160 yunF F Protein of unknown function DUF72
CIMHLLIM_01635 3.4e-129 cobB K SIR2 family
CIMHLLIM_01636 1.6e-177
CIMHLLIM_01637 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CIMHLLIM_01638 2.1e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CIMHLLIM_01639 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIMHLLIM_01640 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
CIMHLLIM_01641 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
CIMHLLIM_01642 0.0 helD 3.6.4.12 L DNA helicase
CIMHLLIM_01643 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CIMHLLIM_01645 4.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CIMHLLIM_01646 5.2e-265 yfnA E amino acid
CIMHLLIM_01647 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CIMHLLIM_01648 8.9e-41 1.3.5.4 S FMN binding
CIMHLLIM_01649 7.1e-220 norA EGP Major facilitator Superfamily
CIMHLLIM_01650 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CIMHLLIM_01651 6.3e-154 metQ1 P Belongs to the nlpA lipoprotein family
CIMHLLIM_01652 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIMHLLIM_01653 3.1e-103 metI P ABC transporter permease
CIMHLLIM_01654 1.2e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CIMHLLIM_01655 6e-189 clcA P chloride
CIMHLLIM_01656 8.8e-215 L transposase, IS605 OrfB family
CIMHLLIM_01657 3.4e-58 L PFAM transposase IS200-family protein
CIMHLLIM_01658 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CIMHLLIM_01659 1.9e-102 proW P ABC transporter, permease protein
CIMHLLIM_01660 6.5e-142 proV E ABC transporter, ATP-binding protein
CIMHLLIM_01661 3.1e-105 proWZ P ABC transporter permease
CIMHLLIM_01662 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
CIMHLLIM_01663 3.8e-73 K Transcriptional regulator
CIMHLLIM_01664 1.6e-35 1.6.5.2 GM NAD(P)H-binding
CIMHLLIM_01666 3.7e-221 5.4.2.7 G Metalloenzyme superfamily
CIMHLLIM_01667 1.3e-299 cadA P P-type ATPase
CIMHLLIM_01668 1.3e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
CIMHLLIM_01669 2.3e-125
CIMHLLIM_01670 2.6e-52 S Sugar efflux transporter for intercellular exchange
CIMHLLIM_01671 6.1e-244 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
CIMHLLIM_01673 0.0 L Helicase C-terminal domain protein
CIMHLLIM_01674 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
CIMHLLIM_01675 4.1e-178 S Aldo keto reductase
CIMHLLIM_01677 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIMHLLIM_01678 1.9e-26 psiE S Phosphate-starvation-inducible E
CIMHLLIM_01679 5.9e-97 ydeN S Serine hydrolase
CIMHLLIM_01681 2.2e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CIMHLLIM_01682 1.2e-253 nhaC C Na H antiporter NhaC
CIMHLLIM_01683 2.5e-36 S Cytochrome b5-like Heme/Steroid binding domain
CIMHLLIM_01684 1.8e-113 ywnB S NAD(P)H-binding
CIMHLLIM_01685 7e-36
CIMHLLIM_01686 3.3e-127 IQ Dehydrogenase reductase
CIMHLLIM_01687 4.9e-238 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
CIMHLLIM_01688 1.9e-18 3.2.1.18 GH33 M Rib/alpha-like repeat
CIMHLLIM_01689 8.2e-70 K Transcriptional regulator, HxlR family
CIMHLLIM_01690 8.4e-189 EGP Major facilitator Superfamily
CIMHLLIM_01692 2.4e-260 mco Q Multicopper oxidase
CIMHLLIM_01694 8.2e-85 tra L Transposase and inactivated derivatives, IS30 family
CIMHLLIM_01695 3.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CIMHLLIM_01697 1.7e-218 S cog cog1373
CIMHLLIM_01698 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
CIMHLLIM_01699 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIMHLLIM_01700 4.7e-157 EG EamA-like transporter family
CIMHLLIM_01701 1.3e-36 Q pyridine nucleotide-disulphide oxidoreductase
CIMHLLIM_01702 0.0 helD 3.6.4.12 L DNA helicase
CIMHLLIM_01703 2e-115 dedA S SNARE associated Golgi protein
CIMHLLIM_01704 5e-127 3.1.3.73 G phosphoglycerate mutase
CIMHLLIM_01705 8.6e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIMHLLIM_01706 6.6e-35 S Transglycosylase associated protein
CIMHLLIM_01708 2.1e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIMHLLIM_01709 5.3e-221 V domain protein
CIMHLLIM_01710 7.8e-94 K Transcriptional regulator (TetR family)
CIMHLLIM_01711 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
CIMHLLIM_01712 1e-148
CIMHLLIM_01713 3.1e-17 3.2.1.14 GH18
CIMHLLIM_01714 2.1e-81 zur P Belongs to the Fur family
CIMHLLIM_01715 1.5e-98 gmk2 2.7.4.8 F Guanylate kinase
CIMHLLIM_01716 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
CIMHLLIM_01717 3e-254 yfnA E Amino Acid
CIMHLLIM_01718 2.2e-230 EGP Sugar (and other) transporter
CIMHLLIM_01719 6e-32
CIMHLLIM_01720 9.5e-18
CIMHLLIM_01721 5.8e-53
CIMHLLIM_01722 2e-33
CIMHLLIM_01723 5.2e-206 potD P ABC transporter
CIMHLLIM_01724 6.5e-140 potC P ABC transporter permease
CIMHLLIM_01725 4.5e-146 potB P ABC transporter permease
CIMHLLIM_01726 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CIMHLLIM_01727 0.0 2.7.7.6 M Peptidase family M23
CIMHLLIM_01728 2.1e-117 rfbP 2.7.8.6 M Bacterial sugar transferase
CIMHLLIM_01729 1e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
CIMHLLIM_01730 1.9e-146 cps1D M Domain of unknown function (DUF4422)
CIMHLLIM_01731 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
CIMHLLIM_01732 4.9e-31
CIMHLLIM_01733 6.6e-34 S Protein of unknown function (DUF2922)
CIMHLLIM_01734 1.8e-143 yihY S Belongs to the UPF0761 family
CIMHLLIM_01735 3.4e-280 yjeM E Amino Acid
CIMHLLIM_01736 9.5e-256 E Arginine ornithine antiporter
CIMHLLIM_01737 1.6e-221 arcT 2.6.1.1 E Aminotransferase
CIMHLLIM_01738 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
CIMHLLIM_01739 1.4e-78 fld C Flavodoxin
CIMHLLIM_01740 1.3e-67 gtcA S Teichoic acid glycosylation protein
CIMHLLIM_01741 7.1e-56
CIMHLLIM_01742 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CIMHLLIM_01744 1.9e-231 yfmL L DEAD DEAH box helicase
CIMHLLIM_01745 5.9e-191 mocA S Oxidoreductase
CIMHLLIM_01746 9.1e-62 S Domain of unknown function (DUF4828)
CIMHLLIM_01747 1.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
CIMHLLIM_01748 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CIMHLLIM_01749 2.2e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CIMHLLIM_01750 3e-195 S Protein of unknown function (DUF3114)
CIMHLLIM_01751 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
CIMHLLIM_01752 7.3e-116 ybhL S Belongs to the BI1 family
CIMHLLIM_01753 7.2e-43 S Phage tail tube protein
CIMHLLIM_01754 2.5e-28 S Protein of unknown function (DUF3168)
CIMHLLIM_01755 2.4e-30 S Bacteriophage HK97-gp10, putative tail-component
CIMHLLIM_01756 7.3e-36
CIMHLLIM_01757 6.8e-31 S Phage gp6-like head-tail connector protein
CIMHLLIM_01758 6.7e-32
CIMHLLIM_01759 4.9e-42 S Domain of unknown function (DUF4355)
CIMHLLIM_01761 4.4e-61 S Phage Mu protein F like protein
CIMHLLIM_01762 3.1e-140 S Phage portal protein
CIMHLLIM_01763 3.8e-26 ps334 S Terminase-like family
CIMHLLIM_01764 1.9e-55 ps333 L Terminase small subunit
CIMHLLIM_01765 1e-58 S HicB_like antitoxin of bacterial toxin-antitoxin system
CIMHLLIM_01768 1.9e-58
CIMHLLIM_01769 3.7e-75 S LemA family
CIMHLLIM_01770 2.4e-33
CIMHLLIM_01779 1e-28
CIMHLLIM_01781 3.5e-38 S ORF6C domain
CIMHLLIM_01784 7.3e-26
CIMHLLIM_01785 1.1e-22 L Replication initiation and membrane attachment
CIMHLLIM_01786 3.5e-67 S PDDEXK-like domain of unknown function (DUF3799)
CIMHLLIM_01787 8.7e-64 recT L RecT family
CIMHLLIM_01791 6.5e-33
CIMHLLIM_01796 1.1e-112 K BRO family, N-terminal domain
CIMHLLIM_01797 7.8e-12
CIMHLLIM_01799 2.6e-13
CIMHLLIM_01800 7.5e-41 ps115 K Helix-turn-helix XRE-family like proteins
CIMHLLIM_01801 3.5e-20 E Zn peptidase
CIMHLLIM_01802 4.9e-72
CIMHLLIM_01806 3.7e-235 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
CIMHLLIM_01807 2.7e-197 gntT EG Gluconate
CIMHLLIM_01808 4.9e-182 K Transcriptional regulator, LacI family
CIMHLLIM_01809 4.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
CIMHLLIM_01810 6.7e-93
CIMHLLIM_01811 3.6e-25
CIMHLLIM_01812 3.7e-61 asp S Asp23 family, cell envelope-related function
CIMHLLIM_01813 1.6e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
CIMHLLIM_01815 1.1e-25
CIMHLLIM_01816 2.7e-67 yqkB S Belongs to the HesB IscA family
CIMHLLIM_01817 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
CIMHLLIM_01818 8.1e-79 F NUDIX domain
CIMHLLIM_01819 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIMHLLIM_01820 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIMHLLIM_01821 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CIMHLLIM_01822 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
CIMHLLIM_01823 1.7e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CIMHLLIM_01824 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
CIMHLLIM_01825 3.7e-45 yktA S Belongs to the UPF0223 family
CIMHLLIM_01826 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CIMHLLIM_01827 0.0 typA T GTP-binding protein TypA
CIMHLLIM_01828 2.7e-222 ftsW D Belongs to the SEDS family
CIMHLLIM_01829 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
CIMHLLIM_01830 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
CIMHLLIM_01831 8.7e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CIMHLLIM_01832 1.8e-195 ylbL T Belongs to the peptidase S16 family
CIMHLLIM_01833 5.8e-80 comEA L Competence protein ComEA
CIMHLLIM_01834 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
CIMHLLIM_01835 0.0 comEC S Competence protein ComEC
CIMHLLIM_01836 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
CIMHLLIM_01837 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
CIMHLLIM_01838 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIMHLLIM_01839 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIMHLLIM_01840 1.6e-163 S Tetratricopeptide repeat
CIMHLLIM_01841 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIMHLLIM_01842 1.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CIMHLLIM_01843 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIMHLLIM_01844 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
CIMHLLIM_01845 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
CIMHLLIM_01846 4.9e-08
CIMHLLIM_01847 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CIMHLLIM_01848 9.7e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIMHLLIM_01849 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CIMHLLIM_01850 2.1e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CIMHLLIM_01851 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CIMHLLIM_01852 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CIMHLLIM_01853 4.8e-87
CIMHLLIM_01855 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIMHLLIM_01856 2.4e-209 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
CIMHLLIM_01857 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CIMHLLIM_01858 1.3e-35 ynzC S UPF0291 protein
CIMHLLIM_01859 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
CIMHLLIM_01860 4.6e-117 plsC 2.3.1.51 I Acyltransferase
CIMHLLIM_01861 2.7e-140 yabB 2.1.1.223 L Methyltransferase small domain
CIMHLLIM_01862 7.1e-49 yazA L GIY-YIG catalytic domain protein
CIMHLLIM_01863 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIMHLLIM_01864 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
CIMHLLIM_01865 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIMHLLIM_01866 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CIMHLLIM_01867 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CIMHLLIM_01868 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIMHLLIM_01869 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
CIMHLLIM_01870 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CIMHLLIM_01871 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CIMHLLIM_01872 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIMHLLIM_01873 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
CIMHLLIM_01874 2.3e-215 nusA K Participates in both transcription termination and antitermination
CIMHLLIM_01875 1e-44 ylxR K Protein of unknown function (DUF448)
CIMHLLIM_01876 1.3e-48 ylxQ J ribosomal protein
CIMHLLIM_01877 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIMHLLIM_01878 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIMHLLIM_01879 7.1e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIMHLLIM_01880 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CIMHLLIM_01881 2.9e-63
CIMHLLIM_01882 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CIMHLLIM_01883 3.9e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIMHLLIM_01884 0.0 dnaK O Heat shock 70 kDa protein
CIMHLLIM_01885 2.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CIMHLLIM_01886 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CIMHLLIM_01887 2e-274 pipD E Dipeptidase
CIMHLLIM_01888 1.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
CIMHLLIM_01890 5.7e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CIMHLLIM_01891 7.5e-58
CIMHLLIM_01892 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
CIMHLLIM_01893 6.7e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CIMHLLIM_01894 9.4e-50
CIMHLLIM_01895 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIMHLLIM_01896 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CIMHLLIM_01897 9.3e-166 yniA G Phosphotransferase enzyme family
CIMHLLIM_01898 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CIMHLLIM_01899 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIMHLLIM_01900 1.1e-262 glnPH2 P ABC transporter permease
CIMHLLIM_01901 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CIMHLLIM_01902 8.6e-70 yqeY S YqeY-like protein
CIMHLLIM_01903 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CIMHLLIM_01904 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CIMHLLIM_01905 3.5e-263 argH 4.3.2.1 E argininosuccinate lyase
CIMHLLIM_01906 3.8e-83 bioY S BioY family
CIMHLLIM_01907 1.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CIMHLLIM_01908 4.5e-183 phoH T phosphate starvation-inducible protein PhoH
CIMHLLIM_01909 1.2e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CIMHLLIM_01910 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CIMHLLIM_01911 3.6e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CIMHLLIM_01912 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
CIMHLLIM_01913 2.9e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CIMHLLIM_01914 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CIMHLLIM_01915 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CIMHLLIM_01916 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CIMHLLIM_01917 2.4e-220 patA 2.6.1.1 E Aminotransferase
CIMHLLIM_01918 4.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
CIMHLLIM_01919 8.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CIMHLLIM_01920 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CIMHLLIM_01921 2e-29 S Protein of unknown function (DUF2929)
CIMHLLIM_01922 0.0 dnaE 2.7.7.7 L DNA polymerase
CIMHLLIM_01923 1.4e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CIMHLLIM_01924 3.5e-168 cvfB S S1 domain
CIMHLLIM_01925 9.1e-164 xerD D recombinase XerD
CIMHLLIM_01926 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIMHLLIM_01927 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIMHLLIM_01928 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIMHLLIM_01929 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CIMHLLIM_01930 6e-100 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CIMHLLIM_01931 3.3e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
CIMHLLIM_01932 1.4e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
CIMHLLIM_01933 2.5e-13 M Lysin motif
CIMHLLIM_01934 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CIMHLLIM_01935 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
CIMHLLIM_01936 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CIMHLLIM_01937 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CIMHLLIM_01938 1.4e-234 S Tetratricopeptide repeat protein
CIMHLLIM_01939 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CIMHLLIM_01940 0.0 yfmR S ABC transporter, ATP-binding protein
CIMHLLIM_01941 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIMHLLIM_01942 1.6e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CIMHLLIM_01943 1.3e-111 hlyIII S protein, hemolysin III
CIMHLLIM_01944 6.4e-151 DegV S EDD domain protein, DegV family
CIMHLLIM_01945 1.8e-167 ypmR E lipolytic protein G-D-S-L family
CIMHLLIM_01946 8.2e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
CIMHLLIM_01947 8.4e-34 yozE S Belongs to the UPF0346 family
CIMHLLIM_01948 5.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CIMHLLIM_01949 2.1e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIMHLLIM_01950 3.3e-118 dprA LU DNA protecting protein DprA
CIMHLLIM_01951 1e-95 L Belongs to the 'phage' integrase family
CIMHLLIM_01953 1.9e-19
CIMHLLIM_01954 6.8e-39 S Pfam:DUF955
CIMHLLIM_01955 9.3e-21 xre K Helix-turn-helix domain
CIMHLLIM_01965 5.6e-34 S Protein of unknown function (DUF1071)
CIMHLLIM_01966 7.4e-73 S Putative HNHc nuclease
CIMHLLIM_01967 1.9e-21 L Single-stranded DNA-binding protein
CIMHLLIM_01969 5.2e-28 K Conserved phage C-terminus (Phg_2220_C)
CIMHLLIM_01970 5.7e-40 dnaC 3.4.21.53 L IstB-like ATP binding protein
CIMHLLIM_01974 1.9e-52 S Protein of unknown function (DUF1064)
CIMHLLIM_01975 2.3e-184 L Belongs to the 'phage' integrase family
CIMHLLIM_01976 2.2e-122 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
CIMHLLIM_01977 1.2e-14
CIMHLLIM_01982 2.1e-18
CIMHLLIM_01984 1.1e-14 arpU S Phage transcriptional regulator, ArpU family
CIMHLLIM_01986 1.7e-55 S N-methyltransferase activity
CIMHLLIM_01987 4.3e-38
CIMHLLIM_01988 6.3e-42 L transposase activity
CIMHLLIM_01989 4.9e-192 ps334 S Terminase-like family
CIMHLLIM_01990 1.2e-139 S Phage portal protein
CIMHLLIM_01991 2e-85 S Phage Mu protein F like protein
CIMHLLIM_01992 1e-25 S sequence-specific DNA binding transcription factor activity
CIMHLLIM_01993 2.5e-41 S Domain of unknown function (DUF4355)
CIMHLLIM_01994 6.7e-32
CIMHLLIM_01995 6.8e-31 S Phage gp6-like head-tail connector protein
CIMHLLIM_01996 7.3e-36
CIMHLLIM_01997 2.4e-30 S Bacteriophage HK97-gp10, putative tail-component
CIMHLLIM_01998 2.5e-28 S Protein of unknown function (DUF3168)
CIMHLLIM_01999 7.2e-43 S Phage tail tube protein
CIMHLLIM_02000 5.5e-33 S Uncharacterised protein family (UPF0236)
CIMHLLIM_02001 9.5e-39 S Cytochrome B5
CIMHLLIM_02002 1.4e-72
CIMHLLIM_02003 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CIMHLLIM_02004 7e-131 ponA V Beta-lactamase enzyme family
CIMHLLIM_02005 4.9e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
CIMHLLIM_02006 8.2e-216 uhpT EGP Major facilitator Superfamily
CIMHLLIM_02007 1.7e-259 ytjP 3.5.1.18 E Dipeptidase
CIMHLLIM_02008 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
CIMHLLIM_02010 5.9e-23 S Phage tail assembly chaperone protein, TAC
CIMHLLIM_02011 7.7e-23 S Phage tail assembly chaperone protein, TAC
CIMHLLIM_02012 5.2e-181 yfeX P Peroxidase
CIMHLLIM_02013 3.7e-205 amtB P ammonium transporter
CIMHLLIM_02014 6.8e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
CIMHLLIM_02015 8.6e-84 yvbK 3.1.3.25 K GNAT family
CIMHLLIM_02016 1.7e-91
CIMHLLIM_02017 4.1e-121 pnb C nitroreductase
CIMHLLIM_02018 2.4e-75 ogt 2.1.1.63 L Methyltransferase
CIMHLLIM_02019 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
CIMHLLIM_02020 6.8e-67 S Protein of unknown function (DUF3021)
CIMHLLIM_02021 6e-76 K LytTr DNA-binding domain
CIMHLLIM_02022 1.1e-92 K Acetyltransferase (GNAT) family
CIMHLLIM_02024 1.4e-18 L Transposase IS66 family
CIMHLLIM_02027 4.9e-60 XK27_01125 L PFAM IS66 Orf2 family protein
CIMHLLIM_02028 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
CIMHLLIM_02029 4.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
CIMHLLIM_02030 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CIMHLLIM_02031 1.2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CIMHLLIM_02032 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
CIMHLLIM_02033 9.7e-178 yagE E amino acid
CIMHLLIM_02034 4.6e-52 yagE E amino acid
CIMHLLIM_02035 3.8e-84 dps P Belongs to the Dps family
CIMHLLIM_02036 0.0 pacL 3.6.3.8 P P-type ATPase
CIMHLLIM_02037 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
CIMHLLIM_02038 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CIMHLLIM_02039 1e-37 D Antitoxin component of a toxin-antitoxin (TA) module
CIMHLLIM_02040 1.3e-48 S ParE toxin of type II toxin-antitoxin system, parDE
CIMHLLIM_02041 1.3e-18 ywlG S Belongs to the UPF0340 family
CIMHLLIM_02042 8.6e-159 spoU 2.1.1.185 J Methyltransferase
CIMHLLIM_02043 1.3e-224 oxlT P Major Facilitator Superfamily
CIMHLLIM_02044 2e-109 2.1.1.72 V Type II restriction enzyme, methylase subunits
CIMHLLIM_02045 1.8e-34 2.1.1.72 V Type II restriction enzyme, methylase subunits
CIMHLLIM_02046 2.5e-258 G Major Facilitator Superfamily
CIMHLLIM_02047 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
CIMHLLIM_02048 1.4e-163 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CIMHLLIM_02049 3.8e-182 pbuG S permease
CIMHLLIM_02050 6.3e-257 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CIMHLLIM_02051 3.3e-71 L Helix-turn-helix domain
CIMHLLIM_02052 1.9e-134 L hmm pf00665
CIMHLLIM_02053 4.4e-48 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CIMHLLIM_02054 4.2e-49 ebh D nuclear chromosome segregation
CIMHLLIM_02055 1.6e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIMHLLIM_02056 6.1e-181 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
CIMHLLIM_02057 5.6e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CIMHLLIM_02058 1.3e-47 Z012_10770 M Domain of unknown function (DUF1919)
CIMHLLIM_02059 2.3e-07 M Glycosyl transferases group 1
CIMHLLIM_02060 2.4e-60 S Glycosyltransferase, group 2 family protein
CIMHLLIM_02061 6.2e-38 M Glycosyltransferase sugar-binding region containing DXD motif
CIMHLLIM_02062 5.3e-45 cpsJ M Glycosyltransferase like family 2
CIMHLLIM_02063 4.8e-38 M Glycosyltransferase sugar-binding region containing DXD motif
CIMHLLIM_02064 6.1e-67 cps2I S Psort location CytoplasmicMembrane, score
CIMHLLIM_02066 2.1e-33 2.4.1.166 GT2 M Glycosyltransferase like family 2
CIMHLLIM_02067 1.5e-83 lsgF M Glycosyl transferase family 2
CIMHLLIM_02068 2.2e-50 pglC M Bacterial sugar transferase
CIMHLLIM_02069 2.8e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
CIMHLLIM_02070 9e-140 epsB M biosynthesis protein
CIMHLLIM_02071 4.9e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CIMHLLIM_02072 2.6e-40 K Transcriptional regulator, HxlR family
CIMHLLIM_02073 3.5e-61 K DNA-templated transcription, initiation
CIMHLLIM_02074 4.7e-35
CIMHLLIM_02075 1.1e-264 L PFAM Integrase catalytic region
CIMHLLIM_02076 4.3e-86
CIMHLLIM_02077 6.6e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CIMHLLIM_02078 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CIMHLLIM_02079 2.5e-311 yjbQ P TrkA C-terminal domain protein
CIMHLLIM_02080 4.9e-273 pipD E Dipeptidase
CIMHLLIM_02081 0.0 trxB2 1.8.1.9 C Thioredoxin domain
CIMHLLIM_02082 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
CIMHLLIM_02083 3.7e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CIMHLLIM_02084 1.1e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
CIMHLLIM_02087 2.5e-185 L transposase, IS605 OrfB family
CIMHLLIM_02088 4.2e-49 L Transposase IS200 like
CIMHLLIM_02089 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIMHLLIM_02090 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
CIMHLLIM_02091 8.2e-224 mdtG EGP Major facilitator Superfamily
CIMHLLIM_02092 8.9e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CIMHLLIM_02093 6.8e-74 4.4.1.5 E Glyoxalase
CIMHLLIM_02094 2.1e-137 S Membrane
CIMHLLIM_02095 5.5e-138 S Belongs to the UPF0246 family
CIMHLLIM_02096 3.7e-67 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
CIMHLLIM_02097 9.1e-126 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
CIMHLLIM_02098 2e-32 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
CIMHLLIM_02099 1.1e-33 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
CIMHLLIM_02100 2e-36 S Uncharacterised protein family (UPF0236)
CIMHLLIM_02102 1.3e-28 ebh D nuclear chromosome segregation
CIMHLLIM_02106 2.2e-09 S zinc-ribbon domain
CIMHLLIM_02107 3.6e-47
CIMHLLIM_02108 2.8e-49 agrA K LytTr DNA-binding domain
CIMHLLIM_02109 1.8e-59 S Double zinc ribbon
CIMHLLIM_02110 9.8e-186 2.7.13.3 T GHKL domain
CIMHLLIM_02116 1.1e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CIMHLLIM_02117 1.5e-275 lysP E amino acid
CIMHLLIM_02118 6.6e-09 2.3.1.128 J Acetyltransferase (GNAT) domain
CIMHLLIM_02119 4.4e-118 lssY 3.6.1.27 I phosphatase
CIMHLLIM_02120 1e-81 S Threonine/Serine exporter, ThrE
CIMHLLIM_02121 2e-127 thrE S Putative threonine/serine exporter
CIMHLLIM_02122 1e-30 cspC K Cold shock protein
CIMHLLIM_02123 1.6e-123 sirR K iron dependent repressor
CIMHLLIM_02124 5.5e-164 czcD P cation diffusion facilitator family transporter
CIMHLLIM_02125 2.5e-116 S membrane
CIMHLLIM_02126 8.4e-109 S VIT family
CIMHLLIM_02127 5.5e-83 usp1 T Belongs to the universal stress protein A family
CIMHLLIM_02128 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIMHLLIM_02129 7.5e-152 glnH ET ABC transporter
CIMHLLIM_02130 2.4e-110 gluC P ABC transporter permease
CIMHLLIM_02131 1e-108 glnP P ABC transporter permease
CIMHLLIM_02132 8.3e-221 S CAAX protease self-immunity
CIMHLLIM_02133 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIMHLLIM_02134 2.9e-57
CIMHLLIM_02135 3.4e-74 merR K MerR HTH family regulatory protein
CIMHLLIM_02136 7.2e-270 lmrB EGP Major facilitator Superfamily
CIMHLLIM_02137 2.7e-121 S Domain of unknown function (DUF4811)
CIMHLLIM_02138 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CIMHLLIM_02140 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIMHLLIM_02141 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
CIMHLLIM_02142 9.4e-186 I Alpha beta
CIMHLLIM_02143 6.5e-271 emrY EGP Major facilitator Superfamily
CIMHLLIM_02144 4.7e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
CIMHLLIM_02145 9.4e-253 yjjP S Putative threonine/serine exporter
CIMHLLIM_02146 3.9e-159 mleR K LysR family
CIMHLLIM_02148 5.7e-85 ltrA S Bacterial low temperature requirement A protein (LtrA)
CIMHLLIM_02149 1.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
CIMHLLIM_02150 4.3e-13
CIMHLLIM_02159 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CIMHLLIM_02160 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
CIMHLLIM_02161 4.2e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CIMHLLIM_02162 7e-256 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
CIMHLLIM_02163 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CIMHLLIM_02164 2.9e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CIMHLLIM_02165 4.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CIMHLLIM_02166 1.2e-124 IQ reductase
CIMHLLIM_02167 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CIMHLLIM_02168 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIMHLLIM_02169 7.9e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIMHLLIM_02170 1.2e-76 marR K Transcriptional regulator, MarR family
CIMHLLIM_02171 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CIMHLLIM_02173 1.3e-201 xerS L Belongs to the 'phage' integrase family
CIMHLLIM_02174 5.8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
CIMHLLIM_02175 1.8e-164 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
CIMHLLIM_02176 1.6e-53 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
CIMHLLIM_02177 3e-156 rssA S Phospholipase, patatin family
CIMHLLIM_02178 9.4e-118 L Integrase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)