ORF_ID e_value Gene_name EC_number CAZy COGs Description
HIKPOOAF_00019 9.3e-168 arsB 1.20.4.1 P Sodium Bile acid symporter family
HIKPOOAF_00020 6.2e-35 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HIKPOOAF_00022 8.5e-65 repB L Initiator Replication protein
HIKPOOAF_00023 1.1e-199
HIKPOOAF_00025 9.1e-38 K Helix-turn-helix domain
HIKPOOAF_00026 2e-53 S Phage derived protein Gp49-like (DUF891)
HIKPOOAF_00027 1.2e-95 L Integrase
HIKPOOAF_00029 0.0 tetP J of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome
HIKPOOAF_00030 2.4e-12 fhaB M Rib/alpha-like repeat
HIKPOOAF_00031 4.4e-31 arsB 1.20.4.1 P Sodium Bile acid symporter family
HIKPOOAF_00034 7.6e-21 K Helix-turn-helix domain
HIKPOOAF_00035 1.9e-21 D nuclear chromosome segregation
HIKPOOAF_00039 2.8e-138 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIKPOOAF_00041 2.4e-59 S Plasmid replication protein
HIKPOOAF_00042 1.6e-15
HIKPOOAF_00043 5.4e-125 L Belongs to the 'phage' integrase family
HIKPOOAF_00045 2.9e-14 K Cro/C1-type HTH DNA-binding domain
HIKPOOAF_00049 1.7e-263 dtpT U amino acid peptide transporter
HIKPOOAF_00050 1.1e-147 yjjH S Calcineurin-like phosphoesterase
HIKPOOAF_00053 9.4e-110
HIKPOOAF_00054 6.5e-249 EGP Major facilitator Superfamily
HIKPOOAF_00055 1.1e-300 aspT P Predicted Permease Membrane Region
HIKPOOAF_00056 8.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HIKPOOAF_00057 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HIKPOOAF_00058 6.9e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIKPOOAF_00059 4.4e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIKPOOAF_00060 0.0 yhgF K Tex-like protein N-terminal domain protein
HIKPOOAF_00061 1.5e-82 ydcK S Belongs to the SprT family
HIKPOOAF_00063 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HIKPOOAF_00064 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HIKPOOAF_00065 0.0 S Bacterial membrane protein, YfhO
HIKPOOAF_00066 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIKPOOAF_00067 3.8e-167 I alpha/beta hydrolase fold
HIKPOOAF_00068 2.9e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIKPOOAF_00069 1.1e-119 tcyB E ABC transporter
HIKPOOAF_00070 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIKPOOAF_00071 4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HIKPOOAF_00072 6.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
HIKPOOAF_00073 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIKPOOAF_00074 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
HIKPOOAF_00075 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HIKPOOAF_00076 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIKPOOAF_00077 1.1e-204 yacL S domain protein
HIKPOOAF_00078 1.3e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIKPOOAF_00079 4.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIKPOOAF_00080 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIKPOOAF_00081 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HIKPOOAF_00082 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIKPOOAF_00083 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HIKPOOAF_00084 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIKPOOAF_00085 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIKPOOAF_00086 2.8e-224 aadAT EK Aminotransferase, class I
HIKPOOAF_00088 1.8e-32 M Glycosyl transferase family group 2
HIKPOOAF_00089 6.3e-154 M Glycosyl transferase family group 2
HIKPOOAF_00090 4e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIKPOOAF_00091 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIKPOOAF_00092 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIKPOOAF_00093 5.7e-35
HIKPOOAF_00094 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIKPOOAF_00095 8.9e-56 K transcriptional regulator PadR family
HIKPOOAF_00096 1.1e-80 XK27_06920 S Protein of unknown function (DUF1700)
HIKPOOAF_00097 2e-115 S Putative adhesin
HIKPOOAF_00098 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HIKPOOAF_00099 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIKPOOAF_00100 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIKPOOAF_00101 3.4e-35 nrdH O Glutaredoxin
HIKPOOAF_00102 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIKPOOAF_00103 3.6e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIKPOOAF_00104 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIKPOOAF_00105 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIKPOOAF_00106 2.8e-38 S Protein of unknown function (DUF2508)
HIKPOOAF_00107 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIKPOOAF_00108 2.9e-51 yaaQ S Cyclic-di-AMP receptor
HIKPOOAF_00109 8.4e-182 holB 2.7.7.7 L DNA polymerase III
HIKPOOAF_00110 3.1e-43 yabA L Involved in initiation control of chromosome replication
HIKPOOAF_00111 6.4e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIKPOOAF_00112 5.4e-133 fat 3.1.2.21 I Acyl-ACP thioesterase
HIKPOOAF_00113 2.8e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HIKPOOAF_00114 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HIKPOOAF_00115 1.2e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HIKPOOAF_00116 5.7e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HIKPOOAF_00117 3.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HIKPOOAF_00118 8.9e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HIKPOOAF_00119 1.4e-192 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIKPOOAF_00120 6.8e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIKPOOAF_00121 7.6e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HIKPOOAF_00122 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIKPOOAF_00123 5.6e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HIKPOOAF_00124 2.9e-226 mtnE 2.6.1.83 E Aminotransferase
HIKPOOAF_00125 2e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIKPOOAF_00126 0.0 uup S ABC transporter, ATP-binding protein
HIKPOOAF_00127 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIKPOOAF_00129 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIKPOOAF_00130 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIKPOOAF_00131 5.3e-81 S Aminoacyl-tRNA editing domain
HIKPOOAF_00132 4.5e-302 ybeC E amino acid
HIKPOOAF_00133 0.0 ydaO E amino acid
HIKPOOAF_00134 2.7e-39
HIKPOOAF_00135 6.2e-67 rmaI K Transcriptional regulator
HIKPOOAF_00136 5.1e-152 EGP Major facilitator Superfamily
HIKPOOAF_00137 1.3e-36 EGP Major facilitator Superfamily
HIKPOOAF_00138 1.3e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HIKPOOAF_00139 6.2e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HIKPOOAF_00140 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HIKPOOAF_00141 5.5e-45 yitW S Pfam:DUF59
HIKPOOAF_00142 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIKPOOAF_00143 2.5e-258 G Major Facilitator Superfamily
HIKPOOAF_00144 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HIKPOOAF_00145 8e-164 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HIKPOOAF_00146 3.8e-182 pbuG S permease
HIKPOOAF_00147 6.3e-257 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HIKPOOAF_00148 1.1e-64 L Helix-turn-helix domain
HIKPOOAF_00149 5e-135 L hmm pf00665
HIKPOOAF_00154 1.4e-297 mco Q Multicopper oxidase
HIKPOOAF_00155 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HIKPOOAF_00156 4.1e-64 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIKPOOAF_00157 6.6e-153 tesE Q hydratase
HIKPOOAF_00158 3.3e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HIKPOOAF_00160 2e-42 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HIKPOOAF_00161 5.9e-84 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
HIKPOOAF_00162 1.1e-107 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HIKPOOAF_00163 3.8e-38 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HIKPOOAF_00164 7.8e-207 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HIKPOOAF_00165 1.7e-102 ycsF S LamB/YcsF family
HIKPOOAF_00166 4e-178 ycsG P Natural resistance-associated macrophage protein
HIKPOOAF_00167 1.4e-54 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIKPOOAF_00168 1.2e-86 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIKPOOAF_00169 8.2e-212 yfnA E Amino Acid
HIKPOOAF_00170 1.5e-176 S FRG
HIKPOOAF_00171 8.8e-15
HIKPOOAF_00173 1.5e-169 whiA K May be required for sporulation
HIKPOOAF_00174 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HIKPOOAF_00175 4.1e-161 rapZ S Displays ATPase and GTPase activities
HIKPOOAF_00176 5.4e-245 steT E amino acid
HIKPOOAF_00177 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIKPOOAF_00178 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIKPOOAF_00179 6.9e-14
HIKPOOAF_00180 5.1e-116 yfbR S HD containing hydrolase-like enzyme
HIKPOOAF_00181 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HIKPOOAF_00182 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
HIKPOOAF_00183 8.5e-162 aatB ET PFAM extracellular solute-binding protein, family 3
HIKPOOAF_00184 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HIKPOOAF_00185 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIKPOOAF_00186 2.7e-168 lutA C Cysteine-rich domain
HIKPOOAF_00187 5e-292 lutB C 4Fe-4S dicluster domain
HIKPOOAF_00188 1.7e-136 yrjD S LUD domain
HIKPOOAF_00189 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIKPOOAF_00190 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HIKPOOAF_00191 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIKPOOAF_00192 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIKPOOAF_00193 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HIKPOOAF_00194 7.7e-31 KT PspC domain protein
HIKPOOAF_00195 1.1e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIKPOOAF_00196 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIKPOOAF_00197 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIKPOOAF_00198 6.6e-114 comFC S Competence protein
HIKPOOAF_00199 3.1e-248 comFA L Helicase C-terminal domain protein
HIKPOOAF_00200 1.1e-107 yvyE 3.4.13.9 S YigZ family
HIKPOOAF_00201 1.6e-180 galR K Transcriptional regulator
HIKPOOAF_00202 2e-277 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HIKPOOAF_00203 5.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIKPOOAF_00204 9.2e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HIKPOOAF_00205 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
HIKPOOAF_00206 1.5e-91 yxkA S Phosphatidylethanolamine-binding protein
HIKPOOAF_00207 9.1e-36
HIKPOOAF_00208 2e-52
HIKPOOAF_00209 5.3e-201
HIKPOOAF_00210 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIKPOOAF_00211 2.9e-134 pnuC H nicotinamide mononucleotide transporter
HIKPOOAF_00212 1.1e-155 ytbE 1.1.1.346 S Aldo keto reductase
HIKPOOAF_00213 1.2e-123 K response regulator
HIKPOOAF_00214 2.6e-180 T PhoQ Sensor
HIKPOOAF_00215 1.9e-133 macB2 V ABC transporter, ATP-binding protein
HIKPOOAF_00216 0.0 ysaB V FtsX-like permease family
HIKPOOAF_00217 4.5e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HIKPOOAF_00218 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIKPOOAF_00219 6.2e-10 K helix_turn_helix, mercury resistance
HIKPOOAF_00220 8.4e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIKPOOAF_00221 2e-195 EGP Major facilitator Superfamily
HIKPOOAF_00222 6e-88 ymdB S Macro domain protein
HIKPOOAF_00223 1.4e-105 K Helix-turn-helix XRE-family like proteins
HIKPOOAF_00224 0.0 pepO 3.4.24.71 O Peptidase family M13
HIKPOOAF_00225 1.4e-47
HIKPOOAF_00226 3.9e-232 S Putative metallopeptidase domain
HIKPOOAF_00227 4.9e-202 3.1.3.1 S associated with various cellular activities
HIKPOOAF_00228 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HIKPOOAF_00229 5.9e-64 yeaO S Protein of unknown function, DUF488
HIKPOOAF_00231 4.4e-118 yrkL S Flavodoxin-like fold
HIKPOOAF_00232 1.5e-52
HIKPOOAF_00233 5.3e-16 S Domain of unknown function (DUF4767)
HIKPOOAF_00234 2.3e-30 2.1.1.72 D peptidase
HIKPOOAF_00235 1.7e-47
HIKPOOAF_00236 2.6e-205 nrnB S DHHA1 domain
HIKPOOAF_00237 1.8e-226 S Uncharacterized protein conserved in bacteria (DUF2325)
HIKPOOAF_00238 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
HIKPOOAF_00239 1.1e-104 NU mannosyl-glycoprotein
HIKPOOAF_00240 2.1e-140 S Putative ABC-transporter type IV
HIKPOOAF_00241 1.9e-273 S ABC transporter, ATP-binding protein
HIKPOOAF_00242 4.9e-18 K Helix-turn-helix domain
HIKPOOAF_00243 2e-44 arsB 1.20.4.1 P Sodium Bile acid symporter family
HIKPOOAF_00244 8.9e-18 D FIVAR domain
HIKPOOAF_00245 4.1e-45 L PFAM Integrase catalytic region
HIKPOOAF_00246 5.5e-110 dedA S SNARE-like domain protein
HIKPOOAF_00247 7.3e-102 S Protein of unknown function (DUF1461)
HIKPOOAF_00248 1.6e-132 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIKPOOAF_00249 6.6e-93 yutD S Protein of unknown function (DUF1027)
HIKPOOAF_00250 4.7e-111 S Calcineurin-like phosphoesterase
HIKPOOAF_00251 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIKPOOAF_00252 2.1e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
HIKPOOAF_00254 1e-67
HIKPOOAF_00255 4.6e-40
HIKPOOAF_00256 1.1e-77 NU general secretion pathway protein
HIKPOOAF_00257 7.1e-47 comGC U competence protein ComGC
HIKPOOAF_00258 1.2e-180 comGB NU type II secretion system
HIKPOOAF_00259 4.9e-179 comGA NU Type II IV secretion system protein
HIKPOOAF_00260 1.3e-131 yebC K Transcriptional regulatory protein
HIKPOOAF_00261 1.3e-132
HIKPOOAF_00262 1e-179 ccpA K catabolite control protein A
HIKPOOAF_00263 2.3e-209 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HIKPOOAF_00264 6.6e-17
HIKPOOAF_00265 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIKPOOAF_00266 6.9e-148 ykuT M mechanosensitive ion channel
HIKPOOAF_00267 1.8e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HIKPOOAF_00268 1.1e-74 ykuL S (CBS) domain
HIKPOOAF_00269 3.4e-94 S Phosphoesterase
HIKPOOAF_00270 3.7e-105 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIKPOOAF_00271 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HIKPOOAF_00272 3e-96 yslB S Protein of unknown function (DUF2507)
HIKPOOAF_00273 1.8e-53 trxA O Belongs to the thioredoxin family
HIKPOOAF_00274 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIKPOOAF_00275 2.7e-86 cvpA S Colicin V production protein
HIKPOOAF_00276 6.1e-48 yrzB S Belongs to the UPF0473 family
HIKPOOAF_00277 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIKPOOAF_00278 4.1e-43 yrzL S Belongs to the UPF0297 family
HIKPOOAF_00279 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIKPOOAF_00280 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIKPOOAF_00281 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HIKPOOAF_00282 6.2e-31 yajC U Preprotein translocase
HIKPOOAF_00283 5e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HIKPOOAF_00284 1.1e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIKPOOAF_00285 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIKPOOAF_00286 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIKPOOAF_00287 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIKPOOAF_00288 1.2e-208 rny S Endoribonuclease that initiates mRNA decay
HIKPOOAF_00289 1.7e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIKPOOAF_00290 8.1e-227 cinA 3.5.1.42 S Belongs to the CinA family
HIKPOOAF_00291 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIKPOOAF_00292 5e-137 ymfM S Helix-turn-helix domain
HIKPOOAF_00293 1e-248 ymfH S Peptidase M16
HIKPOOAF_00294 5.3e-226 ymfF S Peptidase M16 inactive domain protein
HIKPOOAF_00295 1.7e-159 aatB ET ABC transporter substrate-binding protein
HIKPOOAF_00296 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIKPOOAF_00297 3.2e-102 glnP P ABC transporter permease
HIKPOOAF_00298 8.7e-93 mreD M rod shape-determining protein MreD
HIKPOOAF_00299 3.5e-152 mreC M Involved in formation and maintenance of cell shape
HIKPOOAF_00300 1.7e-179 mreB D cell shape determining protein MreB
HIKPOOAF_00301 8e-122 radC L DNA repair protein
HIKPOOAF_00302 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HIKPOOAF_00303 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
HIKPOOAF_00304 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HIKPOOAF_00305 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HIKPOOAF_00306 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HIKPOOAF_00307 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
HIKPOOAF_00308 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIKPOOAF_00309 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIKPOOAF_00310 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HIKPOOAF_00311 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIKPOOAF_00312 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIKPOOAF_00313 4.6e-73 L PFAM Integrase catalytic region
HIKPOOAF_00314 1.4e-51 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIKPOOAF_00326 4.4e-57 M Peptidase_C39 like family
HIKPOOAF_00327 3.2e-53 ponA V the current gene model (or a revised gene model) may contain a frame shift
HIKPOOAF_00328 6e-64 gntR1 K Transcriptional regulator, GntR family
HIKPOOAF_00329 1.2e-155 V ABC transporter, ATP-binding protein
HIKPOOAF_00330 8.4e-117
HIKPOOAF_00331 6.8e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HIKPOOAF_00332 2e-98 S Pfam:DUF3816
HIKPOOAF_00333 0.0 clpE O Belongs to the ClpA ClpB family
HIKPOOAF_00334 6.4e-27
HIKPOOAF_00335 2.7e-39 ptsH G phosphocarrier protein HPR
HIKPOOAF_00336 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIKPOOAF_00337 2.7e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HIKPOOAF_00338 2.9e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
HIKPOOAF_00339 8.7e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIKPOOAF_00340 3.3e-39 ykuJ S Protein of unknown function (DUF1797)
HIKPOOAF_00341 2.5e-84
HIKPOOAF_00342 9.6e-196 L Belongs to the 'phage' integrase family
HIKPOOAF_00343 3.7e-20 S DNA binding domain, excisionase family
HIKPOOAF_00345 1.5e-06
HIKPOOAF_00346 3.4e-57 L Resolvase, N terminal domain
HIKPOOAF_00347 2.8e-10 L Resolvase, N terminal domain
HIKPOOAF_00350 1e-104 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIKPOOAF_00351 2.1e-44
HIKPOOAF_00352 1.6e-10
HIKPOOAF_00353 6.9e-92 yciB M ErfK YbiS YcfS YnhG
HIKPOOAF_00354 7.1e-163 S Putative peptidoglycan binding domain
HIKPOOAF_00356 1.4e-43 hxlR K Transcriptional regulator, HxlR family
HIKPOOAF_00357 9.1e-160 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HIKPOOAF_00358 1e-20 L Helix-turn-helix domain
HIKPOOAF_00359 5e-82 L Helix-turn-helix domain
HIKPOOAF_00360 8.7e-122 O Zinc-dependent metalloprotease
HIKPOOAF_00361 9.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIKPOOAF_00362 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
HIKPOOAF_00364 0.0 M Leucine-rich repeat (LRR) protein
HIKPOOAF_00365 0.0 UW LPXTG-motif cell wall anchor domain protein
HIKPOOAF_00366 5.8e-184 S Phosphotransferase system, EIIC
HIKPOOAF_00367 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIKPOOAF_00368 3.9e-182
HIKPOOAF_00369 4.7e-63 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIKPOOAF_00370 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HIKPOOAF_00371 1.2e-31 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIKPOOAF_00372 4.7e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIKPOOAF_00373 9.1e-95 2.3.1.128 K acetyltransferase
HIKPOOAF_00374 8.7e-187
HIKPOOAF_00375 4.4e-17 K Transcriptional regulator, HxlR family
HIKPOOAF_00376 3.6e-131 K Transcriptional regulatory protein, C-terminal domain protein
HIKPOOAF_00377 4.6e-160 pstS P Phosphate
HIKPOOAF_00378 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
HIKPOOAF_00379 5.9e-155 pstA P Phosphate transport system permease protein PstA
HIKPOOAF_00380 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIKPOOAF_00381 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
HIKPOOAF_00382 7.3e-134
HIKPOOAF_00383 6.5e-243 ydaM M Glycosyl transferase
HIKPOOAF_00384 1.1e-222 G Glycosyl hydrolases family 8
HIKPOOAF_00385 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HIKPOOAF_00386 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HIKPOOAF_00387 1.7e-238 ktrB P Potassium uptake protein
HIKPOOAF_00388 7.7e-115 ktrA P domain protein
HIKPOOAF_00389 4.2e-79 Q Methyltransferase
HIKPOOAF_00390 3e-232 mntH P H( )-stimulated, divalent metal cation uptake system
HIKPOOAF_00391 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HIKPOOAF_00392 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIKPOOAF_00393 3.2e-95 S NADPH-dependent FMN reductase
HIKPOOAF_00394 1.8e-179 MA20_14895 S Conserved hypothetical protein 698
HIKPOOAF_00395 5.1e-133 I alpha/beta hydrolase fold
HIKPOOAF_00396 6.1e-112 lsa S ABC transporter
HIKPOOAF_00397 4.8e-30 lsa S ABC transporter
HIKPOOAF_00398 1e-65 lsa S ABC transporter
HIKPOOAF_00400 4.7e-260 G Major Facilitator
HIKPOOAF_00401 8.9e-176 K Transcriptional regulator, LacI family
HIKPOOAF_00402 1.3e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIKPOOAF_00403 8.3e-102 nqr 1.5.1.36 S reductase
HIKPOOAF_00404 7.4e-204 XK27_09615 S reductase
HIKPOOAF_00405 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HIKPOOAF_00406 1.1e-13 K Transcriptional
HIKPOOAF_00407 2.8e-95 cadD P Cadmium resistance transporter
HIKPOOAF_00408 9.4e-56 cadX K Bacterial regulatory protein, arsR family
HIKPOOAF_00409 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIKPOOAF_00410 8.6e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
HIKPOOAF_00412 1.8e-34 2.1.1.72 V Type II restriction enzyme, methylase subunits
HIKPOOAF_00413 2.7e-173 2.1.1.72 V Type II restriction enzyme, methylase subunits
HIKPOOAF_00414 1.3e-224 oxlT P Major Facilitator Superfamily
HIKPOOAF_00415 7.8e-160 spoU 2.1.1.185 J Methyltransferase
HIKPOOAF_00416 5.3e-96 ywlG S Belongs to the UPF0340 family
HIKPOOAF_00417 2.1e-49 S ParE toxin of type II toxin-antitoxin system, parDE
HIKPOOAF_00418 1e-37 D Antitoxin component of a toxin-antitoxin (TA) module
HIKPOOAF_00419 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HIKPOOAF_00420 1.4e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HIKPOOAF_00421 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HIKPOOAF_00422 2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HIKPOOAF_00423 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HIKPOOAF_00424 9.7e-178 yagE E amino acid
HIKPOOAF_00425 5.1e-51 yagE E amino acid
HIKPOOAF_00426 1.7e-84 dps P Belongs to the Dps family
HIKPOOAF_00427 0.0 pacL 3.6.3.8 P P-type ATPase
HIKPOOAF_00428 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HIKPOOAF_00429 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HIKPOOAF_00430 0.0 rafA 3.2.1.22 G alpha-galactosidase
HIKPOOAF_00431 9.7e-186 galR K Periplasmic binding protein-like domain
HIKPOOAF_00432 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HIKPOOAF_00433 8.2e-117 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIKPOOAF_00434 3e-108 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HIKPOOAF_00435 3.9e-50 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HIKPOOAF_00436 4e-148 f42a O Band 7 protein
HIKPOOAF_00437 3.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HIKPOOAF_00438 1e-153 yitU 3.1.3.104 S hydrolase
HIKPOOAF_00439 9.2e-39 S Cytochrome B5
HIKPOOAF_00440 3.4e-115 nreC K PFAM regulatory protein LuxR
HIKPOOAF_00441 5.2e-159 hipB K Helix-turn-helix
HIKPOOAF_00442 2.8e-57 yitW S Iron-sulfur cluster assembly protein
HIKPOOAF_00443 1.2e-271 sufB O assembly protein SufB
HIKPOOAF_00444 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
HIKPOOAF_00445 1.2e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIKPOOAF_00446 1.7e-240 sufD O FeS assembly protein SufD
HIKPOOAF_00447 2.7e-143 sufC O FeS assembly ATPase SufC
HIKPOOAF_00448 9.6e-32 feoA P FeoA domain
HIKPOOAF_00449 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HIKPOOAF_00450 9.8e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HIKPOOAF_00451 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HIKPOOAF_00452 3e-60 ydiI Q Thioesterase superfamily
HIKPOOAF_00453 7.3e-106 yvrI K sigma factor activity
HIKPOOAF_00454 2.9e-197 G Transporter, major facilitator family protein
HIKPOOAF_00455 0.0 S Bacterial membrane protein YfhO
HIKPOOAF_00456 2.5e-103 T Ion transport 2 domain protein
HIKPOOAF_00457 6.4e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HIKPOOAF_00458 3.9e-84 yvbK 3.1.3.25 K GNAT family
HIKPOOAF_00459 2.9e-91
HIKPOOAF_00460 8.3e-122 pnb C nitroreductase
HIKPOOAF_00461 1.2e-74 ogt 2.1.1.63 L Methyltransferase
HIKPOOAF_00462 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HIKPOOAF_00463 3.7e-65 S Protein of unknown function (DUF3021)
HIKPOOAF_00464 1.9e-74 K LytTr DNA-binding domain
HIKPOOAF_00465 3.7e-93 K Acetyltransferase (GNAT) family
HIKPOOAF_00466 1.6e-20
HIKPOOAF_00467 1.1e-69 yhjX P Major Facilitator Superfamily
HIKPOOAF_00468 5.4e-119 ybhL S Belongs to the BI1 family
HIKPOOAF_00469 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HIKPOOAF_00470 1.3e-193 S Protein of unknown function (DUF3114)
HIKPOOAF_00471 2.4e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HIKPOOAF_00472 9.4e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HIKPOOAF_00473 1.9e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HIKPOOAF_00474 9.1e-62 S Domain of unknown function (DUF4828)
HIKPOOAF_00475 1.3e-190 mocA S Oxidoreductase
HIKPOOAF_00476 8.2e-230 yfmL L DEAD DEAH box helicase
HIKPOOAF_00478 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIKPOOAF_00479 7.1e-56
HIKPOOAF_00480 1.3e-67 gtcA S Teichoic acid glycosylation protein
HIKPOOAF_00481 1.4e-78 fld C Flavodoxin
HIKPOOAF_00482 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
HIKPOOAF_00483 1.3e-220 arcT 2.6.1.1 E Aminotransferase
HIKPOOAF_00484 1.4e-254 E Arginine ornithine antiporter
HIKPOOAF_00485 2e-280 yjeM E Amino Acid
HIKPOOAF_00486 4e-151 yihY S Belongs to the UPF0761 family
HIKPOOAF_00487 5e-34 S Protein of unknown function (DUF2922)
HIKPOOAF_00488 4.9e-31
HIKPOOAF_00489 3.7e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
HIKPOOAF_00490 4.3e-146 cps1D M Domain of unknown function (DUF4422)
HIKPOOAF_00491 1.7e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HIKPOOAF_00492 8.5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
HIKPOOAF_00493 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
HIKPOOAF_00494 1.4e-215 cps3F
HIKPOOAF_00495 4.4e-104 M biosynthesis protein
HIKPOOAF_00496 8.3e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HIKPOOAF_00497 1e-198 waaB GT4 M Glycosyl transferases group 1
HIKPOOAF_00498 1.5e-191 M transferase activity, transferring glycosyl groups
HIKPOOAF_00499 1.2e-194 S enterobacterial common antigen metabolic process
HIKPOOAF_00500 3.6e-125 acmD M repeat protein
HIKPOOAF_00501 3.2e-07 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIKPOOAF_00502 2e-77 O Bacterial dnaA protein
HIKPOOAF_00503 1.8e-34 O Bacterial dnaA protein
HIKPOOAF_00504 9.6e-43 L Transposase
HIKPOOAF_00505 1.4e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIKPOOAF_00506 2.6e-264 glnP P ABC transporter
HIKPOOAF_00507 5.5e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIKPOOAF_00508 2.1e-220 cycA E Amino acid permease
HIKPOOAF_00509 5.1e-218 nupG F Nucleoside transporter
HIKPOOAF_00510 3.3e-169 rihC 3.2.2.1 F Nucleoside
HIKPOOAF_00511 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HIKPOOAF_00512 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HIKPOOAF_00513 1.1e-146 noc K Belongs to the ParB family
HIKPOOAF_00514 3.6e-140 soj D Sporulation initiation inhibitor
HIKPOOAF_00515 2.5e-153 spo0J K Belongs to the ParB family
HIKPOOAF_00516 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
HIKPOOAF_00517 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIKPOOAF_00518 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
HIKPOOAF_00519 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIKPOOAF_00520 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HIKPOOAF_00521 1.2e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HIKPOOAF_00522 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HIKPOOAF_00523 1.2e-169 deoR K sugar-binding domain protein
HIKPOOAF_00524 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIKPOOAF_00525 3.8e-125 K response regulator
HIKPOOAF_00526 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
HIKPOOAF_00527 2.3e-138 azlC E AzlC protein
HIKPOOAF_00528 1.6e-52 azlD S branched-chain amino acid
HIKPOOAF_00529 6.6e-124 K LysR substrate binding domain
HIKPOOAF_00530 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HIKPOOAF_00531 2.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIKPOOAF_00532 3.3e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIKPOOAF_00533 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIKPOOAF_00534 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIKPOOAF_00535 3.1e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HIKPOOAF_00536 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HIKPOOAF_00537 1.8e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HIKPOOAF_00538 6.6e-174 K AI-2E family transporter
HIKPOOAF_00539 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HIKPOOAF_00540 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HIKPOOAF_00541 4.5e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HIKPOOAF_00542 2.7e-24 K helix_turn_helix, arabinose operon control protein
HIKPOOAF_00543 3.4e-187 thrC 4.2.3.1 E Threonine synthase
HIKPOOAF_00544 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HIKPOOAF_00545 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIKPOOAF_00546 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIKPOOAF_00547 1.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIKPOOAF_00548 8.9e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIKPOOAF_00549 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HIKPOOAF_00550 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIKPOOAF_00551 3.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIKPOOAF_00552 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIKPOOAF_00553 7.6e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIKPOOAF_00554 9.5e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HIKPOOAF_00555 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIKPOOAF_00556 1.7e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HIKPOOAF_00557 6.2e-243 purD 6.3.4.13 F Belongs to the GARS family
HIKPOOAF_00558 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIKPOOAF_00559 2.3e-166
HIKPOOAF_00560 2.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIKPOOAF_00561 2e-09 IQ KR domain
HIKPOOAF_00562 4e-113 IQ KR domain
HIKPOOAF_00563 3.3e-133 S membrane transporter protein
HIKPOOAF_00564 7.9e-97 S ABC-type cobalt transport system, permease component
HIKPOOAF_00565 1.2e-247 cbiO1 S ABC transporter, ATP-binding protein
HIKPOOAF_00566 9.5e-110 P Cobalt transport protein
HIKPOOAF_00567 1.6e-52 yvlA
HIKPOOAF_00568 0.0 yjcE P Sodium proton antiporter
HIKPOOAF_00569 1.4e-51 ypaA S Protein of unknown function (DUF1304)
HIKPOOAF_00570 2e-172 D Alpha beta
HIKPOOAF_00571 6.5e-72 K Transcriptional regulator
HIKPOOAF_00572 1.7e-159
HIKPOOAF_00573 7.9e-132 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKPOOAF_00574 5.3e-158 S Membrane transport protein
HIKPOOAF_00575 3.9e-84 K FCD
HIKPOOAF_00576 1.3e-137 1.6.5.5 C Zinc-binding dehydrogenase
HIKPOOAF_00577 7.2e-256 G PTS system Galactitol-specific IIC component
HIKPOOAF_00578 4.1e-212 EGP Major facilitator Superfamily
HIKPOOAF_00579 4.4e-134 V ABC transporter
HIKPOOAF_00580 9e-106
HIKPOOAF_00581 8.9e-14
HIKPOOAF_00582 7.1e-63
HIKPOOAF_00583 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HIKPOOAF_00584 6.6e-81 uspA T universal stress protein
HIKPOOAF_00585 0.0 tetP J elongation factor G
HIKPOOAF_00586 2.9e-165 GK ROK family
HIKPOOAF_00587 7.2e-237 brnQ U Component of the transport system for branched-chain amino acids
HIKPOOAF_00588 4.2e-138 aroD S Serine hydrolase (FSH1)
HIKPOOAF_00589 4.6e-80 yagE E amino acid
HIKPOOAF_00590 4.7e-116 yagE E amino acid
HIKPOOAF_00591 2.4e-17 yagE E amino acid
HIKPOOAF_00592 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HIKPOOAF_00593 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
HIKPOOAF_00594 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIKPOOAF_00595 2.6e-269 pipD E Dipeptidase
HIKPOOAF_00596 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HIKPOOAF_00597 0.0 yfiC V ABC transporter
HIKPOOAF_00598 1.8e-288 lmrA V ABC transporter, ATP-binding protein
HIKPOOAF_00599 1.3e-17 K Winged helix DNA-binding domain
HIKPOOAF_00600 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKPOOAF_00601 2.9e-19 S PFAM Archaeal ATPase
HIKPOOAF_00602 1.1e-71 S ECF transporter, substrate-specific component
HIKPOOAF_00603 1.3e-50 S Domain of unknown function (DUF4430)
HIKPOOAF_00604 7e-55 cnrT EG PFAM EamA-like transporter family
HIKPOOAF_00605 1.6e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HIKPOOAF_00606 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HIKPOOAF_00607 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
HIKPOOAF_00608 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HIKPOOAF_00609 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
HIKPOOAF_00610 4.3e-239 hemL 5.4.3.8 H Aminotransferase class-III
HIKPOOAF_00611 6.2e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
HIKPOOAF_00612 9.8e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HIKPOOAF_00613 5.4e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HIKPOOAF_00614 2.7e-58 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
HIKPOOAF_00615 6.6e-239 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HIKPOOAF_00616 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
HIKPOOAF_00617 6.8e-103 cbiQ P Cobalt transport protein
HIKPOOAF_00618 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HIKPOOAF_00619 8.5e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HIKPOOAF_00620 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HIKPOOAF_00621 1.8e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
HIKPOOAF_00622 2.7e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HIKPOOAF_00623 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
HIKPOOAF_00624 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HIKPOOAF_00625 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
HIKPOOAF_00626 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HIKPOOAF_00627 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HIKPOOAF_00628 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HIKPOOAF_00629 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HIKPOOAF_00630 5.5e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
HIKPOOAF_00631 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HIKPOOAF_00632 2.1e-204 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HIKPOOAF_00633 1.8e-169 cobD 4.1.1.81 E Aminotransferase class I and II
HIKPOOAF_00634 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
HIKPOOAF_00635 7.9e-117 XK27_04590 S NADPH-dependent FMN reductase
HIKPOOAF_00636 2.9e-73 fld C Flavodoxin
HIKPOOAF_00637 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
HIKPOOAF_00638 5.9e-68 P Cadmium resistance transporter
HIKPOOAF_00639 3.3e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
HIKPOOAF_00640 4.4e-117 3.1.3.48 T Pfam:Y_phosphatase3C
HIKPOOAF_00641 3e-54 pduU E BMC
HIKPOOAF_00642 3.8e-218 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIKPOOAF_00643 4.3e-203 pduQ C Iron-containing alcohol dehydrogenase
HIKPOOAF_00644 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HIKPOOAF_00645 4.5e-77 pduO S Haem-degrading
HIKPOOAF_00646 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HIKPOOAF_00647 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HIKPOOAF_00648 1.3e-79 S Putative propanediol utilisation
HIKPOOAF_00649 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HIKPOOAF_00650 7.8e-40 pduA_4 CQ BMC
HIKPOOAF_00651 3.6e-57 pduK CQ BMC
HIKPOOAF_00652 4.5e-45 pduH S Dehydratase medium subunit
HIKPOOAF_00653 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
HIKPOOAF_00654 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
HIKPOOAF_00655 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HIKPOOAF_00656 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HIKPOOAF_00657 2.7e-134 pduB E BMC
HIKPOOAF_00658 1.6e-37 pduA_4 CQ BMC
HIKPOOAF_00659 8.3e-159 K helix_turn_helix, arabinose operon control protein
HIKPOOAF_00660 3.6e-138 eutJ E Hsp70 protein
HIKPOOAF_00661 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HIKPOOAF_00662 2.2e-160
HIKPOOAF_00663 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HIKPOOAF_00664 2.6e-160 S AI-2E family transporter
HIKPOOAF_00665 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
HIKPOOAF_00666 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
HIKPOOAF_00667 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
HIKPOOAF_00668 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
HIKPOOAF_00669 1.4e-153 ypdB V (ABC) transporter
HIKPOOAF_00670 3.5e-236 yhdP S Transporter associated domain
HIKPOOAF_00671 2.7e-82 nrdI F Belongs to the NrdI family
HIKPOOAF_00672 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
HIKPOOAF_00673 4.4e-190 yeaN P Transporter, major facilitator family protein
HIKPOOAF_00674 3.2e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIKPOOAF_00675 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIKPOOAF_00676 2.3e-28
HIKPOOAF_00677 0.0 lacS G Transporter
HIKPOOAF_00678 2.9e-54 ltrA S Bacterial low temperature requirement A protein (LtrA)
HIKPOOAF_00679 8.1e-34 ltrA S Bacterial low temperature requirement A protein (LtrA)
HIKPOOAF_00680 1.6e-79 uspA T universal stress protein
HIKPOOAF_00681 1.4e-78 K AsnC family
HIKPOOAF_00682 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIKPOOAF_00683 4.1e-102 dedA 3.1.3.1 S SNARE associated Golgi protein
HIKPOOAF_00684 1e-28 WQ51_00220 K Helix-turn-helix domain
HIKPOOAF_00685 7.4e-104 S Protein of unknown function (DUF3278)
HIKPOOAF_00686 2.9e-73 M PFAM NLP P60 protein
HIKPOOAF_00687 4.1e-181 ABC-SBP S ABC transporter
HIKPOOAF_00688 3.3e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HIKPOOAF_00689 1.8e-136 XK27_08845 S ABC transporter, ATP-binding protein
HIKPOOAF_00690 5.1e-96 P Cadmium resistance transporter
HIKPOOAF_00691 9.9e-55 K Transcriptional regulator, ArsR family
HIKPOOAF_00692 7.3e-234 mepA V MATE efflux family protein
HIKPOOAF_00693 3.2e-55 trxA O Belongs to the thioredoxin family
HIKPOOAF_00694 6.6e-131 terC P membrane
HIKPOOAF_00695 6.3e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIKPOOAF_00696 2.8e-168 corA P CorA-like Mg2+ transporter protein
HIKPOOAF_00697 2.3e-278 pipD E Dipeptidase
HIKPOOAF_00698 1.6e-241 pbuX F xanthine permease
HIKPOOAF_00699 1.8e-246 nhaC C Na H antiporter NhaC
HIKPOOAF_00700 5.3e-273 S C4-dicarboxylate anaerobic carrier
HIKPOOAF_00701 5.9e-71 IQ Enoyl-(Acyl carrier protein) reductase
HIKPOOAF_00702 4.6e-36 K Bacterial transcriptional regulator
HIKPOOAF_00703 2.7e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
HIKPOOAF_00704 1.2e-39
HIKPOOAF_00705 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIKPOOAF_00706 8.4e-207 gldA 1.1.1.6 C dehydrogenase
HIKPOOAF_00708 4.9e-111 lssY 3.6.1.27 I Acid phosphatase homologues
HIKPOOAF_00709 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HIKPOOAF_00710 2.2e-128 L PFAM transposase IS116 IS110 IS902
HIKPOOAF_00711 3.7e-227 clcA_2 P Chloride transporter, ClC family
HIKPOOAF_00712 6.3e-114 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HIKPOOAF_00713 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIKPOOAF_00714 1.1e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HIKPOOAF_00715 5.6e-74
HIKPOOAF_00716 9.8e-172
HIKPOOAF_00717 2e-175 fecB P Periplasmic binding protein
HIKPOOAF_00718 7.8e-135 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HIKPOOAF_00719 1.2e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIKPOOAF_00720 2.5e-77 S Flavodoxin
HIKPOOAF_00721 3.5e-62 moaE 2.8.1.12 H MoaE protein
HIKPOOAF_00722 3.9e-32 moaD 2.8.1.12 H ThiS family
HIKPOOAF_00723 1.5e-217 narK P Transporter, major facilitator family protein
HIKPOOAF_00724 3.7e-144 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HIKPOOAF_00725 4.4e-172
HIKPOOAF_00726 7.2e-19
HIKPOOAF_00727 4.9e-114 nreC K PFAM regulatory protein LuxR
HIKPOOAF_00728 1e-182 comP 2.7.13.3 F Sensor histidine kinase
HIKPOOAF_00729 2.6e-43
HIKPOOAF_00730 1.2e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HIKPOOAF_00731 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HIKPOOAF_00732 2.2e-221 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HIKPOOAF_00733 1.8e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HIKPOOAF_00734 9.1e-184 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HIKPOOAF_00735 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIKPOOAF_00736 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HIKPOOAF_00737 8.7e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HIKPOOAF_00738 9.6e-129 narI 1.7.5.1 C Nitrate reductase
HIKPOOAF_00739 2.7e-152 EG EamA-like transporter family
HIKPOOAF_00740 9.4e-118 L Integrase
HIKPOOAF_00741 3e-156 rssA S Phospholipase, patatin family
HIKPOOAF_00742 1e-294 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HIKPOOAF_00743 3.3e-200 xerS L Belongs to the 'phage' integrase family
HIKPOOAF_00745 1.1e-69 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIKPOOAF_00746 4.7e-76 marR K Transcriptional regulator, MarR family
HIKPOOAF_00747 1.8e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIKPOOAF_00748 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIKPOOAF_00749 5.3e-154 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HIKPOOAF_00750 3.6e-126 IQ reductase
HIKPOOAF_00751 1.3e-221 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIKPOOAF_00752 1.2e-71 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HIKPOOAF_00753 4e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIKPOOAF_00754 5.7e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HIKPOOAF_00755 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HIKPOOAF_00756 3.7e-137 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HIKPOOAF_00757 1.5e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HIKPOOAF_00766 1.7e-240 L Transposase
HIKPOOAF_00767 3.1e-200 L PFAM transposase, IS4 family protein
HIKPOOAF_00768 2.5e-89 hchA S DJ-1/PfpI family
HIKPOOAF_00769 1.3e-128 C NADH:flavin oxidoreductase / NADH oxidase family
HIKPOOAF_00770 1.4e-20 K helix_turn_helix, Arsenical Resistance Operon Repressor
HIKPOOAF_00771 4e-69 S Uncharacterized protein conserved in bacteria (DUF2263)
HIKPOOAF_00772 9.2e-186 L PFAM Integrase catalytic region
HIKPOOAF_00773 1.3e-121 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HIKPOOAF_00774 7.7e-129 L Belongs to the 'phage' integrase family
HIKPOOAF_00775 4e-19
HIKPOOAF_00778 4.8e-153
HIKPOOAF_00780 1.6e-76 L Resolvase, N terminal domain
HIKPOOAF_00781 3.8e-10 L Resolvase, N terminal domain
HIKPOOAF_00782 2.8e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HIKPOOAF_00786 5e-106 L hmm pf00665
HIKPOOAF_00787 1.9e-11 I Acyltransferase family
HIKPOOAF_00788 2.9e-87 epsIIL S Polysaccharide biosynthesis protein
HIKPOOAF_00789 2.3e-59
HIKPOOAF_00790 1.2e-49 cps4I M Glycosyltransferase like family 2
HIKPOOAF_00791 3.9e-36 pssE S Glycosyltransferase family 28 C-terminal domain
HIKPOOAF_00792 2e-37 pssD M Oligosaccharide biosynthesis protein Alg14 like
HIKPOOAF_00793 4e-93 M O-antigen ligase like membrane protein
HIKPOOAF_00794 1.6e-106 M Glycosyl transferases group 1
HIKPOOAF_00795 1.2e-104 rfbP M Bacterial sugar transferase
HIKPOOAF_00796 5.5e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HIKPOOAF_00797 2.3e-135 epsB M biosynthesis protein
HIKPOOAF_00798 2.2e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIKPOOAF_00799 4.4e-40 K Transcriptional regulator, HxlR family
HIKPOOAF_00800 2.3e-60 K DNA-templated transcription, initiation
HIKPOOAF_00801 4.7e-35
HIKPOOAF_00802 1.8e-264 L PFAM Integrase catalytic region
HIKPOOAF_00803 1.8e-264 L PFAM Integrase catalytic region
HIKPOOAF_00804 1.7e-29
HIKPOOAF_00805 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIKPOOAF_00807 6.6e-91 yxiO S Vacuole effluxer Atg22 like
HIKPOOAF_00808 4.2e-84 yxiO S Vacuole effluxer Atg22 like
HIKPOOAF_00809 1.1e-101 npp S type I phosphodiesterase nucleotide pyrophosphatase
HIKPOOAF_00810 1.7e-47 npp S type I phosphodiesterase nucleotide pyrophosphatase
HIKPOOAF_00811 2.8e-31 npp S type I phosphodiesterase nucleotide pyrophosphatase
HIKPOOAF_00812 5.1e-238 E amino acid
HIKPOOAF_00813 8.6e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIKPOOAF_00814 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIKPOOAF_00816 1.3e-218 yxjG_1 E methionine synthase, vitamin-B12 independent
HIKPOOAF_00817 5.7e-36 S Cytochrome B5
HIKPOOAF_00818 1.5e-74 elaA S Gnat family
HIKPOOAF_00819 2.7e-120 GM NmrA-like family
HIKPOOAF_00820 1.8e-50 hxlR K Transcriptional regulator, HxlR family
HIKPOOAF_00821 1.2e-106 XK27_02070 S Nitroreductase family
HIKPOOAF_00822 1.5e-82 K Transcriptional regulator, HxlR family
HIKPOOAF_00823 1.2e-231
HIKPOOAF_00824 1.9e-209 EGP Major facilitator Superfamily
HIKPOOAF_00825 8.8e-256 pepC 3.4.22.40 E aminopeptidase
HIKPOOAF_00826 2.6e-112 ylbE GM NAD dependent epimerase dehydratase family protein
HIKPOOAF_00827 0.0 pepN 3.4.11.2 E aminopeptidase
HIKPOOAF_00828 5.5e-48 K Transcriptional regulator
HIKPOOAF_00829 1.9e-40 folT S ECF transporter, substrate-specific component
HIKPOOAF_00830 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
HIKPOOAF_00831 1.9e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HIKPOOAF_00832 2e-161 L PFAM Integrase catalytic region
HIKPOOAF_00833 1.8e-264 L PFAM Integrase catalytic region
HIKPOOAF_00834 8.4e-90
HIKPOOAF_00835 6.6e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIKPOOAF_00836 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HIKPOOAF_00837 7.1e-296 yjbQ P TrkA C-terminal domain protein
HIKPOOAF_00838 7.6e-274 pipD E Dipeptidase
HIKPOOAF_00839 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HIKPOOAF_00840 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
HIKPOOAF_00841 3.7e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HIKPOOAF_00842 3e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HIKPOOAF_00845 7.2e-185 L transposase, IS605 OrfB family
HIKPOOAF_00846 1.1e-51 L Transposase IS200 like
HIKPOOAF_00847 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIKPOOAF_00848 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
HIKPOOAF_00849 8.2e-224 mdtG EGP Major facilitator Superfamily
HIKPOOAF_00850 2.6e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HIKPOOAF_00851 4.4e-53 yxjG_1 E methionine synthase, vitamin-B12 independent
HIKPOOAF_00852 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HIKPOOAF_00853 3.2e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIKPOOAF_00854 2.7e-134 D nuclear chromosome segregation
HIKPOOAF_00855 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HIKPOOAF_00856 0.0 lacS G Transporter
HIKPOOAF_00857 2.6e-186 lacR K Transcriptional regulator
HIKPOOAF_00858 3.8e-10
HIKPOOAF_00859 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HIKPOOAF_00860 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
HIKPOOAF_00861 5e-34
HIKPOOAF_00862 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIKPOOAF_00863 1.7e-260 yfnA E amino acid
HIKPOOAF_00864 2.2e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HIKPOOAF_00865 7.6e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIKPOOAF_00866 4.1e-40 ylqC S Belongs to the UPF0109 family
HIKPOOAF_00867 8.5e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HIKPOOAF_00868 8.7e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIKPOOAF_00869 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIKPOOAF_00870 4.2e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIKPOOAF_00871 0.0 smc D Required for chromosome condensation and partitioning
HIKPOOAF_00872 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIKPOOAF_00873 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIKPOOAF_00874 6.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIKPOOAF_00875 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIKPOOAF_00876 0.0 yloV S DAK2 domain fusion protein YloV
HIKPOOAF_00877 4.7e-58 asp S Asp23 family, cell envelope-related function
HIKPOOAF_00878 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HIKPOOAF_00879 2.9e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
HIKPOOAF_00880 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HIKPOOAF_00881 3.6e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIKPOOAF_00882 0.0 KLT serine threonine protein kinase
HIKPOOAF_00883 6.1e-129 stp 3.1.3.16 T phosphatase
HIKPOOAF_00884 9e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIKPOOAF_00885 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIKPOOAF_00886 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIKPOOAF_00887 1.4e-207 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIKPOOAF_00888 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIKPOOAF_00889 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HIKPOOAF_00890 2.7e-52
HIKPOOAF_00891 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
HIKPOOAF_00892 7.3e-77 argR K Regulates arginine biosynthesis genes
HIKPOOAF_00893 1.2e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HIKPOOAF_00894 1.7e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIKPOOAF_00895 6.2e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIKPOOAF_00896 6.8e-179 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIKPOOAF_00897 2.3e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIKPOOAF_00898 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIKPOOAF_00899 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HIKPOOAF_00900 1.7e-114 J 2'-5' RNA ligase superfamily
HIKPOOAF_00901 2.8e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HIKPOOAF_00902 8.9e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HIKPOOAF_00903 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HIKPOOAF_00904 2.4e-53 ysxB J Cysteine protease Prp
HIKPOOAF_00905 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HIKPOOAF_00906 1.4e-110 K Transcriptional regulator
HIKPOOAF_00909 4.3e-86 dut S Protein conserved in bacteria
HIKPOOAF_00910 1.2e-180
HIKPOOAF_00911 2.6e-150
HIKPOOAF_00912 4.8e-51 S Iron-sulfur cluster assembly protein
HIKPOOAF_00913 4.7e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIKPOOAF_00914 3.9e-12
HIKPOOAF_00915 1.8e-41 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HIKPOOAF_00916 1.6e-32 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HIKPOOAF_00917 2.7e-97 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HIKPOOAF_00918 2.2e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIKPOOAF_00919 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
HIKPOOAF_00920 7e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIKPOOAF_00921 5.9e-22 S Protein of unknown function (DUF3042)
HIKPOOAF_00922 3.4e-67 yqhL P Rhodanese-like protein
HIKPOOAF_00923 5.6e-183 glk 2.7.1.2 G Glucokinase
HIKPOOAF_00924 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HIKPOOAF_00925 1.6e-19 gluP 3.4.21.105 S Peptidase, S54 family
HIKPOOAF_00926 6.1e-74 gluP 3.4.21.105 S Peptidase, S54 family
HIKPOOAF_00927 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIKPOOAF_00928 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HIKPOOAF_00929 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HIKPOOAF_00930 0.0 S membrane
HIKPOOAF_00931 4.1e-68 yneR S Belongs to the HesB IscA family
HIKPOOAF_00932 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIKPOOAF_00933 8e-117 udk 2.7.1.48 F Cytidine monophosphokinase
HIKPOOAF_00934 3.6e-114 rlpA M PFAM NLP P60 protein
HIKPOOAF_00935 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIKPOOAF_00936 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIKPOOAF_00937 6.7e-59 yodB K Transcriptional regulator, HxlR family
HIKPOOAF_00938 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIKPOOAF_00939 2.4e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIKPOOAF_00940 1.6e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HIKPOOAF_00941 1.3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIKPOOAF_00942 7.4e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIKPOOAF_00943 8e-233 V MatE
HIKPOOAF_00944 4.8e-266 yjeM E Amino Acid
HIKPOOAF_00945 3.7e-279 arlS 2.7.13.3 T Histidine kinase
HIKPOOAF_00946 1.5e-121 K response regulator
HIKPOOAF_00947 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HIKPOOAF_00948 2.9e-99 yceD S Uncharacterized ACR, COG1399
HIKPOOAF_00949 1.4e-209 ylbM S Belongs to the UPF0348 family
HIKPOOAF_00950 4.6e-137 yqeM Q Methyltransferase
HIKPOOAF_00951 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIKPOOAF_00952 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HIKPOOAF_00953 6.9e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIKPOOAF_00954 1.9e-47 yhbY J RNA-binding protein
HIKPOOAF_00955 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
HIKPOOAF_00956 1.4e-95 yqeG S HAD phosphatase, family IIIA
HIKPOOAF_00957 1.1e-264 L PFAM Integrase catalytic region
HIKPOOAF_00958 1.2e-286 mntH P H( )-stimulated, divalent metal cation uptake system
HIKPOOAF_00959 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HIKPOOAF_00960 1.1e-84 ygfC K transcriptional regulator (TetR family)
HIKPOOAF_00961 2.1e-167 hrtB V ABC transporter permease
HIKPOOAF_00962 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HIKPOOAF_00963 0.0 yhcA V ABC transporter, ATP-binding protein
HIKPOOAF_00964 2.5e-36
HIKPOOAF_00965 4.1e-50 czrA K Transcriptional regulator, ArsR family
HIKPOOAF_00966 1.1e-289 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HIKPOOAF_00967 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIKPOOAF_00968 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIKPOOAF_00969 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIKPOOAF_00970 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HIKPOOAF_00971 1.2e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIKPOOAF_00972 9.8e-67 yabR J RNA binding
HIKPOOAF_00973 5.6e-56 divIC D Septum formation initiator
HIKPOOAF_00974 2.1e-39 yabO J S4 domain protein
HIKPOOAF_00975 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIKPOOAF_00976 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIKPOOAF_00977 1.1e-113 S (CBS) domain
HIKPOOAF_00978 6.4e-145 tesE Q hydratase
HIKPOOAF_00979 1.4e-242 codA 3.5.4.1 F cytosine deaminase
HIKPOOAF_00980 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HIKPOOAF_00981 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
HIKPOOAF_00982 5.3e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIKPOOAF_00983 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIKPOOAF_00985 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKPOOAF_00986 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HIKPOOAF_00987 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIKPOOAF_00988 2.3e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIKPOOAF_00989 1.9e-116 L Transposase
HIKPOOAF_00990 2.6e-20
HIKPOOAF_00991 2.1e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIKPOOAF_00992 1.3e-154 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIKPOOAF_00994 5.3e-123 O Holliday junction DNA helicase ruvB N-terminus
HIKPOOAF_00995 6.8e-224 O Subtilase family
HIKPOOAF_00996 1.8e-49
HIKPOOAF_00997 2.1e-75 S MTH538 TIR-like domain (DUF1863)
HIKPOOAF_00998 3e-80 L Bacterial dnaA protein
HIKPOOAF_00999 2.4e-174 L PFAM Integrase, catalytic core
HIKPOOAF_01000 1.2e-94 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HIKPOOAF_01001 4.1e-62 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase HUMPS family
HIKPOOAF_01002 5.5e-63 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
HIKPOOAF_01003 1.4e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HIKPOOAF_01004 4.8e-99 V Abi-like protein
HIKPOOAF_01005 3.8e-44
HIKPOOAF_01006 1.4e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HIKPOOAF_01007 9.1e-251 mmuP E amino acid
HIKPOOAF_01009 1.2e-41 K Psort location Cytoplasmic, score
HIKPOOAF_01010 2.5e-06 D nuclear chromosome segregation
HIKPOOAF_01011 0.0 snf 2.7.11.1 KL domain protein
HIKPOOAF_01012 4.5e-155 snf 2.7.11.1 KL domain protein
HIKPOOAF_01013 4.1e-144 ywqE 3.1.3.48 GM PHP domain protein
HIKPOOAF_01014 1.2e-205 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HIKPOOAF_01015 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HIKPOOAF_01016 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HIKPOOAF_01017 5.6e-71
HIKPOOAF_01018 3.3e-103 fic D Fic/DOC family
HIKPOOAF_01019 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIKPOOAF_01020 9.8e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HIKPOOAF_01021 2.5e-126 L PFAM Integrase catalytic region
HIKPOOAF_01022 1.5e-73 K Putative DNA-binding domain
HIKPOOAF_01023 2e-123 L PFAM Integrase catalytic region
HIKPOOAF_01024 3.9e-237 L Transposase
HIKPOOAF_01025 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HIKPOOAF_01026 3.7e-216 uhpT EGP Major facilitator Superfamily
HIKPOOAF_01027 4.7e-257 ytjP 3.5.1.18 E Dipeptidase
HIKPOOAF_01028 5.3e-273 arcD S C4-dicarboxylate anaerobic carrier
HIKPOOAF_01029 5.2e-181 yfeX P Peroxidase
HIKPOOAF_01030 3.9e-237 L Transposase
HIKPOOAF_01031 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIKPOOAF_01032 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HIKPOOAF_01033 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIKPOOAF_01034 1.9e-172 dnaI L Primosomal protein DnaI
HIKPOOAF_01035 3e-222 dnaB L replication initiation and membrane attachment
HIKPOOAF_01036 1.9e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIKPOOAF_01037 3.2e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIKPOOAF_01038 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIKPOOAF_01039 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIKPOOAF_01040 1e-15 yoaK S Protein of unknown function (DUF1275)
HIKPOOAF_01041 1.9e-119 ybhL S Belongs to the BI1 family
HIKPOOAF_01042 4.5e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HIKPOOAF_01043 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIKPOOAF_01044 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HIKPOOAF_01045 7.5e-58 ytzB S Small secreted protein
HIKPOOAF_01046 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
HIKPOOAF_01047 1.3e-64 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HIKPOOAF_01048 1.5e-13 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HIKPOOAF_01049 8.2e-23 S YSIRK type signal peptide
HIKPOOAF_01050 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIKPOOAF_01051 1.9e-217 ecsB U ABC transporter
HIKPOOAF_01052 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HIKPOOAF_01053 4.1e-77 hit FG histidine triad
HIKPOOAF_01055 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIKPOOAF_01056 0.0 L AAA domain
HIKPOOAF_01057 9.8e-222 yhaO L Ser Thr phosphatase family protein
HIKPOOAF_01058 9.4e-38 yheA S Belongs to the UPF0342 family
HIKPOOAF_01059 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIKPOOAF_01060 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HIKPOOAF_01061 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIKPOOAF_01062 1.9e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIKPOOAF_01064 1.6e-39
HIKPOOAF_01065 5.1e-43
HIKPOOAF_01066 3.4e-211 folP 2.5.1.15 H dihydropteroate synthase
HIKPOOAF_01067 1.6e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HIKPOOAF_01068 4.7e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HIKPOOAF_01069 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HIKPOOAF_01070 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HIKPOOAF_01071 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIKPOOAF_01072 2.2e-69
HIKPOOAF_01074 1.9e-43
HIKPOOAF_01075 2.7e-109 S CAAX protease self-immunity
HIKPOOAF_01076 1.8e-31
HIKPOOAF_01077 1.2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIKPOOAF_01078 8.7e-187 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HIKPOOAF_01079 2.5e-112
HIKPOOAF_01080 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HIKPOOAF_01081 1e-174 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIKPOOAF_01082 7.3e-86 uspA T Belongs to the universal stress protein A family
HIKPOOAF_01083 1.4e-275 pepV 3.5.1.18 E dipeptidase PepV
HIKPOOAF_01084 2e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIKPOOAF_01085 1.3e-301 ytgP S Polysaccharide biosynthesis protein
HIKPOOAF_01086 4.9e-41
HIKPOOAF_01087 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIKPOOAF_01088 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIKPOOAF_01089 7.9e-94 tag 3.2.2.20 L glycosylase
HIKPOOAF_01090 1e-257 EGP Major facilitator Superfamily
HIKPOOAF_01091 2.8e-84 perR P Belongs to the Fur family
HIKPOOAF_01092 7.7e-231 cycA E Amino acid permease
HIKPOOAF_01093 1.7e-102 V VanZ like family
HIKPOOAF_01094 1e-23
HIKPOOAF_01095 7.8e-117 L transposase IS116 IS110 IS902 family protein
HIKPOOAF_01096 3.9e-237 L Transposase
HIKPOOAF_01097 1.6e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIKPOOAF_01098 1.3e-94 L Helix-turn-helix domain
HIKPOOAF_01099 5.6e-139 L hmm pf00665
HIKPOOAF_01100 3.9e-237 L Transposase
HIKPOOAF_01101 1.3e-129 ponA V Beta-lactamase enzyme family
HIKPOOAF_01102 8.7e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIKPOOAF_01103 3e-75
HIKPOOAF_01104 5.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HIKPOOAF_01105 2.2e-21
HIKPOOAF_01106 3.9e-262 S Uncharacterized protein conserved in bacteria (DUF2252)
HIKPOOAF_01107 4.1e-161 L transposase, IS605 OrfB family
HIKPOOAF_01108 5e-295 L PFAM plasmid pRiA4b ORF-3 family protein
HIKPOOAF_01109 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HIKPOOAF_01110 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIKPOOAF_01111 4.3e-158 mleR K LysR family
HIKPOOAF_01112 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HIKPOOAF_01113 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIKPOOAF_01114 3.1e-267 frdC 1.3.5.4 C FAD binding domain
HIKPOOAF_01115 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
HIKPOOAF_01116 3.9e-159 mleR K LysR family
HIKPOOAF_01117 9.4e-253 yjjP S Putative threonine/serine exporter
HIKPOOAF_01118 1e-116 ung2 3.2.2.27 L Uracil-DNA glycosylase
HIKPOOAF_01119 6.5e-271 emrY EGP Major facilitator Superfamily
HIKPOOAF_01120 9.4e-186 I Alpha beta
HIKPOOAF_01121 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HIKPOOAF_01122 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIKPOOAF_01124 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HIKPOOAF_01125 6.4e-123 S Domain of unknown function (DUF4811)
HIKPOOAF_01126 9.4e-270 lmrB EGP Major facilitator Superfamily
HIKPOOAF_01127 7.5e-74 merR K MerR HTH family regulatory protein
HIKPOOAF_01128 7.9e-55
HIKPOOAF_01129 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIKPOOAF_01130 8.3e-221 S CAAX protease self-immunity
HIKPOOAF_01131 1e-108 glnP P ABC transporter permease
HIKPOOAF_01132 4.2e-110 gluC P ABC transporter permease
HIKPOOAF_01133 9.7e-152 glnH ET ABC transporter
HIKPOOAF_01134 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIKPOOAF_01135 5.5e-83 usp1 T Belongs to the universal stress protein A family
HIKPOOAF_01136 7.6e-110 S VIT family
HIKPOOAF_01137 2.5e-116 S membrane
HIKPOOAF_01138 5.5e-164 czcD P cation diffusion facilitator family transporter
HIKPOOAF_01139 7.7e-123 sirR K iron dependent repressor
HIKPOOAF_01140 1e-30 cspC K Cold shock protein
HIKPOOAF_01141 2.6e-127 thrE S Putative threonine/serine exporter
HIKPOOAF_01142 1e-81 S Threonine/Serine exporter, ThrE
HIKPOOAF_01143 1.5e-118 lssY 3.6.1.27 I phosphatase
HIKPOOAF_01144 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
HIKPOOAF_01145 4.3e-275 lysP E amino acid
HIKPOOAF_01146 5.6e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HIKPOOAF_01152 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HIKPOOAF_01153 1.9e-144 potB P ABC transporter permease
HIKPOOAF_01154 9.3e-139 potC P ABC transporter permease
HIKPOOAF_01155 2.1e-207 potD P ABC transporter
HIKPOOAF_01156 1.7e-106
HIKPOOAF_01157 9.5e-18
HIKPOOAF_01158 6e-32
HIKPOOAF_01159 6.1e-233 EGP Sugar (and other) transporter
HIKPOOAF_01160 3e-254 yfnA E Amino Acid
HIKPOOAF_01161 2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HIKPOOAF_01162 6e-100 gmk2 2.7.4.8 F Guanylate kinase
HIKPOOAF_01163 9.6e-82 zur P Belongs to the Fur family
HIKPOOAF_01164 4e-17 3.2.1.14 GH18
HIKPOOAF_01165 2.7e-149
HIKPOOAF_01166 4.9e-38 pspC KT positive regulation of macromolecule biosynthetic process
HIKPOOAF_01167 1.7e-93 K Transcriptional regulator (TetR family)
HIKPOOAF_01168 4.2e-218 V domain protein
HIKPOOAF_01169 4.6e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKPOOAF_01171 2.1e-33 S Transglycosylase associated protein
HIKPOOAF_01172 1.2e-225 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIKPOOAF_01173 1.5e-126 3.1.3.73 G phosphoglycerate mutase
HIKPOOAF_01174 1.7e-114 dedA S SNARE associated Golgi protein
HIKPOOAF_01175 0.0 helD 3.6.4.12 L DNA helicase
HIKPOOAF_01176 1.3e-36 Q pyridine nucleotide-disulphide oxidoreductase
HIKPOOAF_01177 1.6e-157 EG EamA-like transporter family
HIKPOOAF_01178 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIKPOOAF_01179 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HIKPOOAF_01180 5e-218 S cog cog1373
HIKPOOAF_01182 1.1e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HIKPOOAF_01185 7.2e-71 L PFAM Integrase catalytic region
HIKPOOAF_01187 4e-34 L Transposase IS66 family
HIKPOOAF_01188 2.4e-28 L Transposase IS66 family
HIKPOOAF_01189 9e-46 L Transposase IS66 family
HIKPOOAF_01190 2.2e-238 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HIKPOOAF_01191 1.1e-127 IQ Dehydrogenase reductase
HIKPOOAF_01192 1.4e-36
HIKPOOAF_01193 1.8e-113 ywnB S NAD(P)H-binding
HIKPOOAF_01194 1.2e-253 nhaC C Na H antiporter NhaC
HIKPOOAF_01195 3.8e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIKPOOAF_01197 1.8e-98 ydeN S Serine hydrolase
HIKPOOAF_01198 3.4e-23 psiE S Phosphate-starvation-inducible E
HIKPOOAF_01199 4.5e-23 psiE S Phosphate-starvation-inducible E
HIKPOOAF_01200 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIKPOOAF_01202 9.1e-178 S Aldo keto reductase
HIKPOOAF_01203 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HIKPOOAF_01204 0.0 L Helicase C-terminal domain protein
HIKPOOAF_01206 3.8e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HIKPOOAF_01207 2.6e-52 S Sugar efflux transporter for intercellular exchange
HIKPOOAF_01208 3.9e-125
HIKPOOAF_01209 7.4e-111 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HIKPOOAF_01210 1e-310 cadA P P-type ATPase
HIKPOOAF_01211 3.5e-219 5.4.2.7 G Metalloenzyme superfamily
HIKPOOAF_01213 1.6e-35 1.6.5.2 GM NAD(P)H-binding
HIKPOOAF_01214 4.2e-51 1.6.5.2 GM NAD(P)H-binding
HIKPOOAF_01215 1.4e-72 K Transcriptional regulator
HIKPOOAF_01216 6e-163 proX M ABC transporter, substrate-binding protein, QAT family
HIKPOOAF_01217 2.4e-108 proWZ P ABC transporter permease
HIKPOOAF_01218 6.5e-142 proV E ABC transporter, ATP-binding protein
HIKPOOAF_01219 1.9e-102 proW P ABC transporter, permease protein
HIKPOOAF_01220 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HIKPOOAF_01221 2.3e-60 clcA P chloride
HIKPOOAF_01222 3e-57 clcA P chloride
HIKPOOAF_01223 5.5e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HIKPOOAF_01224 2.6e-102 metI P ABC transporter permease
HIKPOOAF_01225 1.4e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIKPOOAF_01226 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HIKPOOAF_01227 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HIKPOOAF_01228 1.3e-221 norA EGP Major facilitator Superfamily
HIKPOOAF_01229 8.9e-41 1.3.5.4 S FMN binding
HIKPOOAF_01230 2.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIKPOOAF_01231 1.3e-263 yfnA E amino acid
HIKPOOAF_01232 7.7e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIKPOOAF_01234 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HIKPOOAF_01235 0.0 helD 3.6.4.12 L DNA helicase
HIKPOOAF_01236 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
HIKPOOAF_01237 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HIKPOOAF_01238 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIKPOOAF_01239 2.1e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HIKPOOAF_01240 1.8e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HIKPOOAF_01241 2.8e-174
HIKPOOAF_01242 4e-130 cobB K SIR2 family
HIKPOOAF_01244 6.9e-161 yunF F Protein of unknown function DUF72
HIKPOOAF_01245 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIKPOOAF_01246 3.5e-154 tatD L hydrolase, TatD family
HIKPOOAF_01247 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIKPOOAF_01248 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIKPOOAF_01249 6.8e-37 veg S Biofilm formation stimulator VEG
HIKPOOAF_01250 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HIKPOOAF_01251 1.1e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HIKPOOAF_01252 2.2e-122 fhuC P ABC transporter
HIKPOOAF_01253 8e-127 znuB U ABC 3 transport family
HIKPOOAF_01254 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HIKPOOAF_01255 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIKPOOAF_01256 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIKPOOAF_01257 9e-48
HIKPOOAF_01258 2.1e-146 yxeH S hydrolase
HIKPOOAF_01259 1e-270 ywfO S HD domain protein
HIKPOOAF_01260 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HIKPOOAF_01262 0.0 clpL O associated with various cellular activities
HIKPOOAF_01263 7.8e-32
HIKPOOAF_01264 1.8e-215 patA 2.6.1.1 E Aminotransferase
HIKPOOAF_01265 1.6e-172 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKPOOAF_01266 5e-75 osmC O OsmC-like protein
HIKPOOAF_01267 1.1e-84 K FR47-like protein
HIKPOOAF_01268 2.5e-53 L An automated process has identified a potential problem with this gene model
HIKPOOAF_01269 1.2e-08 2.7.13.3 T GHKL domain
HIKPOOAF_01271 7.6e-258 S Putative peptidoglycan binding domain
HIKPOOAF_01272 1.8e-39
HIKPOOAF_01273 6.6e-213 bacI V MacB-like periplasmic core domain
HIKPOOAF_01274 2.8e-128 V ABC transporter
HIKPOOAF_01275 2.8e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIKPOOAF_01276 4.4e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HIKPOOAF_01277 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIKPOOAF_01278 1.9e-149 E Glyoxalase-like domain
HIKPOOAF_01279 7.5e-155 glcU U sugar transport
HIKPOOAF_01280 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HIKPOOAF_01281 2.9e-96 S reductase
HIKPOOAF_01283 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIKPOOAF_01284 1.1e-178 ABC-SBP S ABC transporter
HIKPOOAF_01285 6.8e-84 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HIKPOOAF_01287 1.6e-214 htrA 3.4.21.107 O serine protease
HIKPOOAF_01288 2.3e-153 vicX 3.1.26.11 S domain protein
HIKPOOAF_01289 7.8e-149 yycI S YycH protein
HIKPOOAF_01290 2.4e-245 yycH S YycH protein
HIKPOOAF_01291 0.0 vicK 2.7.13.3 T Histidine kinase
HIKPOOAF_01292 1.7e-128 K response regulator
HIKPOOAF_01294 1.5e-308 lmrA 3.6.3.44 V ABC transporter
HIKPOOAF_01295 1.8e-72 K helix_turn_helix multiple antibiotic resistance protein
HIKPOOAF_01297 5.1e-123 Z012_01130 S Fic/DOC family
HIKPOOAF_01298 2.1e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HIKPOOAF_01299 9.1e-61
HIKPOOAF_01300 6.9e-207 yttB EGP Major facilitator Superfamily
HIKPOOAF_01301 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HIKPOOAF_01302 2e-74 rplI J Binds to the 23S rRNA
HIKPOOAF_01303 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HIKPOOAF_01304 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIKPOOAF_01305 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIKPOOAF_01306 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HIKPOOAF_01307 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIKPOOAF_01308 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIKPOOAF_01309 4.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIKPOOAF_01310 1.9e-33 yaaA S S4 domain protein YaaA
HIKPOOAF_01311 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIKPOOAF_01312 1.1e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIKPOOAF_01313 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HIKPOOAF_01314 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIKPOOAF_01315 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIKPOOAF_01316 9.7e-130 jag S R3H domain protein
HIKPOOAF_01317 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIKPOOAF_01318 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIKPOOAF_01319 0.0 asnB 6.3.5.4 E Asparagine synthase
HIKPOOAF_01320 1.4e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIKPOOAF_01321 3.2e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HIKPOOAF_01322 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HIKPOOAF_01323 2.5e-14 2.3.1.183 M Acetyltransferase GNAT family
HIKPOOAF_01324 7.3e-39 2.3.1.183 M Acetyltransferase GNAT family
HIKPOOAF_01325 2e-161 L PFAM Integrase catalytic region
HIKPOOAF_01326 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HIKPOOAF_01327 1.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIKPOOAF_01328 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HIKPOOAF_01329 3.1e-113 yjbH Q Thioredoxin
HIKPOOAF_01330 1.4e-267 pipD E Dipeptidase
HIKPOOAF_01331 2.6e-194 coiA 3.6.4.12 S Competence protein
HIKPOOAF_01332 3.7e-117 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HIKPOOAF_01333 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIKPOOAF_01334 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HIKPOOAF_01335 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIKPOOAF_01336 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIKPOOAF_01337 0.0 dnaK O Heat shock 70 kDa protein
HIKPOOAF_01338 2.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIKPOOAF_01339 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIKPOOAF_01340 6e-266 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIKPOOAF_01341 5e-104 pncA Q Isochorismatase family
HIKPOOAF_01342 7.7e-129 pnuC H nicotinamide mononucleotide transporter
HIKPOOAF_01343 2e-123 L PFAM Integrase catalytic region
HIKPOOAF_01344 3.5e-29 L PFAM Integrase catalytic region
HIKPOOAF_01345 1.5e-141 S Hydrolases of the alpha beta superfamily
HIKPOOAF_01346 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HIKPOOAF_01347 4.4e-77 ctsR K Belongs to the CtsR family
HIKPOOAF_01348 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HIKPOOAF_01349 3e-110 K Bacterial regulatory proteins, tetR family
HIKPOOAF_01350 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIKPOOAF_01351 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIKPOOAF_01352 3.4e-198 ykiI
HIKPOOAF_01353 5.9e-107 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HIKPOOAF_01354 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIKPOOAF_01355 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIKPOOAF_01356 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIKPOOAF_01357 1.2e-63 L Transposase
HIKPOOAF_01358 1.2e-128 L Transposase
HIKPOOAF_01359 1.8e-192 L transposase IS116 IS110 IS902 family protein
HIKPOOAF_01360 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HIKPOOAF_01361 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIKPOOAF_01362 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HIKPOOAF_01363 4.9e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIKPOOAF_01364 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIKPOOAF_01365 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIKPOOAF_01366 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIKPOOAF_01367 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIKPOOAF_01368 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIKPOOAF_01369 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HIKPOOAF_01370 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIKPOOAF_01371 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIKPOOAF_01372 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIKPOOAF_01373 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIKPOOAF_01374 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIKPOOAF_01375 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIKPOOAF_01376 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIKPOOAF_01377 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIKPOOAF_01378 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIKPOOAF_01379 2.9e-24 rpmD J Ribosomal protein L30
HIKPOOAF_01380 5.8e-63 rplO J Binds to the 23S rRNA
HIKPOOAF_01381 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIKPOOAF_01382 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIKPOOAF_01383 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIKPOOAF_01384 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HIKPOOAF_01385 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIKPOOAF_01386 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIKPOOAF_01387 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIKPOOAF_01388 1.5e-62 rplQ J Ribosomal protein L17
HIKPOOAF_01389 3.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIKPOOAF_01390 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIKPOOAF_01391 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIKPOOAF_01392 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIKPOOAF_01393 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIKPOOAF_01394 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HIKPOOAF_01395 2.7e-140 IQ reductase
HIKPOOAF_01396 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
HIKPOOAF_01397 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIKPOOAF_01398 5.7e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HIKPOOAF_01399 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HIKPOOAF_01400 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIKPOOAF_01401 3.6e-202 camS S sex pheromone
HIKPOOAF_01402 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIKPOOAF_01403 2.7e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIKPOOAF_01404 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIKPOOAF_01405 5.1e-187 yegS 2.7.1.107 G Lipid kinase
HIKPOOAF_01406 2e-12
HIKPOOAF_01407 1.8e-34 doc S Fic/DOC family
HIKPOOAF_01408 3.5e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIKPOOAF_01409 4.6e-235
HIKPOOAF_01410 3.4e-299 hsdM 2.1.1.72 V type I restriction-modification system
HIKPOOAF_01411 1.5e-195 3.1.21.3 V Type I restriction modification DNA specificity domain
HIKPOOAF_01412 2.4e-178 L Belongs to the 'phage' integrase family
HIKPOOAF_01413 1.6e-180 3.1.21.3 V Type I restriction modification DNA specificity domain
HIKPOOAF_01414 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
HIKPOOAF_01415 6.3e-90 entB 3.5.1.19 Q Isochorismatase family
HIKPOOAF_01416 4e-90 K Bacterial regulatory proteins, tetR family
HIKPOOAF_01417 3.1e-34 1.6.5.2 S NADPH-dependent FMN reductase
HIKPOOAF_01418 4.3e-172 L Plasmid pRiA4b ORF-3-like protein
HIKPOOAF_01419 9.3e-61 XK27_04080 H RibD C-terminal domain
HIKPOOAF_01421 2.9e-58 S Protein of unknown function (DUF3021)
HIKPOOAF_01422 4.2e-72 K LytTr DNA-binding domain
HIKPOOAF_01423 1.9e-142 cylB V ABC-2 type transporter
HIKPOOAF_01424 5.3e-153 cylA V ABC transporter
HIKPOOAF_01425 1.5e-44
HIKPOOAF_01426 3.4e-164 L PFAM Integrase catalytic region
HIKPOOAF_01427 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HIKPOOAF_01428 7.9e-35 copZ C Heavy-metal-associated domain
HIKPOOAF_01429 2.7e-94 dps P Belongs to the Dps family
HIKPOOAF_01430 7.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HIKPOOAF_01431 1.3e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
HIKPOOAF_01432 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
HIKPOOAF_01433 3.4e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
HIKPOOAF_01434 1.4e-159 L Recombinase
HIKPOOAF_01435 5.8e-112 L Recombinase zinc beta ribbon domain
HIKPOOAF_01436 1.5e-69 L Recombinase zinc beta ribbon domain
HIKPOOAF_01437 1.8e-18
HIKPOOAF_01438 2.9e-56 S Bacteriophage holin family
HIKPOOAF_01439 6.5e-55 S Phage head-tail joining protein
HIKPOOAF_01440 6.8e-41 S Phage gp6-like head-tail connector protein
HIKPOOAF_01441 2e-176 S Phage capsid family
HIKPOOAF_01442 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIKPOOAF_01443 1.5e-124 3.6.1.13, 3.6.1.55 F NUDIX domain
HIKPOOAF_01444 7.8e-117 L transposase IS116 IS110 IS902 family protein
HIKPOOAF_01445 5e-38 S Alpha beta hydrolase
HIKPOOAF_01446 3.8e-67 S Alpha beta hydrolase
HIKPOOAF_01447 3.7e-216 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIKPOOAF_01448 1.3e-97
HIKPOOAF_01450 1.7e-122 yciB M ErfK YbiS YcfS YnhG
HIKPOOAF_01451 9.5e-261 S Putative peptidoglycan binding domain
HIKPOOAF_01452 3e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HIKPOOAF_01453 1e-87
HIKPOOAF_01454 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HIKPOOAF_01455 5.4e-212 yttB EGP Major facilitator Superfamily
HIKPOOAF_01456 8.2e-103
HIKPOOAF_01457 3.9e-24
HIKPOOAF_01458 1.8e-173 scrR K Transcriptional regulator, LacI family
HIKPOOAF_01460 5.3e-113 frnE Q DSBA-like thioredoxin domain
HIKPOOAF_01461 6.7e-164 I alpha/beta hydrolase fold
HIKPOOAF_01462 5e-20 K Helix-turn-helix XRE-family like proteins
HIKPOOAF_01463 3.3e-35 S Phage derived protein Gp49-like (DUF891)
HIKPOOAF_01464 9.2e-190 ps461 3.5.1.104 M hydrolase, family 25
HIKPOOAF_01465 5.6e-58 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HIKPOOAF_01466 4.9e-34
HIKPOOAF_01468 5.8e-198 cotH M CotH kinase protein
HIKPOOAF_01471 7.3e-63 3.4.24.40 M Peptidase family M23
HIKPOOAF_01472 3.9e-35
HIKPOOAF_01473 2.1e-287 M Prophage endopeptidase tail
HIKPOOAF_01474 1.6e-149 S Phage tail protein
HIKPOOAF_01475 3.1e-237 M Phage tail tape measure protein TP901
HIKPOOAF_01476 3.7e-59 S Phage tail assembly chaperone proteins, TAC
HIKPOOAF_01477 3.9e-133 S Phage tail tube protein
HIKPOOAF_01478 3.4e-67 S Protein of unknown function (DUF806)
HIKPOOAF_01479 7.2e-71 S Bacteriophage HK97-gp10, putative tail-component
HIKPOOAF_01480 1.2e-58 S Phage head-tail joining protein
HIKPOOAF_01481 1e-60 S Phage gp6-like head-tail connector protein
HIKPOOAF_01482 1e-207 S Phage capsid family
HIKPOOAF_01483 7.3e-127 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HIKPOOAF_01484 1.2e-222 S Phage portal protein
HIKPOOAF_01485 0.0 S Phage Terminase
HIKPOOAF_01486 1.9e-09
HIKPOOAF_01488 7.2e-83 L Phage terminase, small subunit
HIKPOOAF_01489 1e-86 L HNH nucleases
HIKPOOAF_01490 1.6e-08
HIKPOOAF_01491 8.9e-12
HIKPOOAF_01492 9.4e-83 arpU S Phage transcriptional regulator, ArpU family
HIKPOOAF_01496 2.1e-69 XK27_00160 S Domain of unknown function (DUF5052)
HIKPOOAF_01502 2.3e-41 S HNH endonuclease
HIKPOOAF_01503 2.2e-09
HIKPOOAF_01505 7e-138 L Belongs to the 'phage' integrase family
HIKPOOAF_01506 1.4e-86 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HIKPOOAF_01507 4.7e-115 L DnaD domain protein
HIKPOOAF_01509 2.1e-31 L HNH endonuclease domain protein
HIKPOOAF_01511 1.7e-19
HIKPOOAF_01512 8.2e-17 K Cro/C1-type HTH DNA-binding domain
HIKPOOAF_01513 9.7e-25
HIKPOOAF_01517 3.6e-18
HIKPOOAF_01518 2.4e-26 ps115 K Helix-turn-helix XRE-family like proteins
HIKPOOAF_01519 3.5e-20 E Zn peptidase
HIKPOOAF_01520 4e-32
HIKPOOAF_01521 1.2e-25
HIKPOOAF_01523 2.2e-29
HIKPOOAF_01525 4.6e-26
HIKPOOAF_01526 5.4e-142 L Belongs to the 'phage' integrase family
HIKPOOAF_01528 8.9e-41 yrvD S Pfam:DUF1049
HIKPOOAF_01529 1.2e-149 3.1.3.102, 3.1.3.104 S hydrolase
HIKPOOAF_01530 1.1e-89 ntd 2.4.2.6 F Nucleoside
HIKPOOAF_01531 2e-18
HIKPOOAF_01532 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HIKPOOAF_01533 4.7e-114 yviA S Protein of unknown function (DUF421)
HIKPOOAF_01534 4.5e-71 S Protein of unknown function (DUF3290)
HIKPOOAF_01535 2.3e-41 ybaN S Protein of unknown function (DUF454)
HIKPOOAF_01536 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIKPOOAF_01537 7.2e-158 endA V DNA/RNA non-specific endonuclease
HIKPOOAF_01538 2.5e-253 yifK E Amino acid permease
HIKPOOAF_01540 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIKPOOAF_01541 2.3e-229 N Uncharacterized conserved protein (DUF2075)
HIKPOOAF_01542 3.7e-120 S SNARE associated Golgi protein
HIKPOOAF_01543 0.0 uvrA3 L excinuclease ABC, A subunit
HIKPOOAF_01544 1e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIKPOOAF_01545 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIKPOOAF_01546 4.6e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIKPOOAF_01547 1.5e-144 S DUF218 domain
HIKPOOAF_01548 0.0 ubiB S ABC1 family
HIKPOOAF_01549 8.5e-246 yhdP S Transporter associated domain
HIKPOOAF_01550 5e-75 copY K Copper transport repressor CopY TcrY
HIKPOOAF_01551 1.4e-243 EGP Major facilitator Superfamily
HIKPOOAF_01552 1.7e-73 yeaL S UPF0756 membrane protein
HIKPOOAF_01553 3.1e-78 yphH S Cupin domain
HIKPOOAF_01554 1.5e-80 C Flavodoxin
HIKPOOAF_01555 3.7e-157 K LysR substrate binding domain protein
HIKPOOAF_01556 1.1e-166 1.1.1.346 C Aldo keto reductase
HIKPOOAF_01557 1.4e-38 gcvR T Belongs to the UPF0237 family
HIKPOOAF_01558 3.9e-243 XK27_08635 S UPF0210 protein
HIKPOOAF_01559 2.4e-95 K Acetyltransferase (GNAT) domain
HIKPOOAF_01560 6.6e-156 S Alpha beta hydrolase
HIKPOOAF_01561 4.6e-157 gspA M family 8
HIKPOOAF_01562 3.4e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIKPOOAF_01563 3.3e-89
HIKPOOAF_01564 2.1e-160 degV S EDD domain protein, DegV family
HIKPOOAF_01565 1.3e-157 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIKPOOAF_01566 4.3e-29
HIKPOOAF_01567 1.1e-147
HIKPOOAF_01568 1.2e-24
HIKPOOAF_01569 1.6e-63 V Beta-lactamase
HIKPOOAF_01570 4.2e-104 V Beta-lactamase
HIKPOOAF_01571 6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HIKPOOAF_01572 1.8e-98 yhiD S MgtC family
HIKPOOAF_01573 1.3e-108 S GyrI-like small molecule binding domain
HIKPOOAF_01574 7.3e-110 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HIKPOOAF_01575 3.2e-50 azlD E Branched-chain amino acid transport
HIKPOOAF_01576 3.1e-119 azlC E azaleucine resistance protein AzlC
HIKPOOAF_01578 3e-155 yocS S SBF-like CPA transporter family (DUF4137)
HIKPOOAF_01579 1.2e-39 S Iron-sulfur cluster assembly protein
HIKPOOAF_01580 0.0 ilvD 4.2.1.9 EG Belongs to the IlvD Edd family
HIKPOOAF_01581 1.7e-176 S amidohydrolase
HIKPOOAF_01582 5e-106 L hmm pf00665
HIKPOOAF_01584 0.0 L PLD-like domain
HIKPOOAF_01586 1.9e-52 K Psort location Cytoplasmic, score
HIKPOOAF_01587 1.4e-14 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HIKPOOAF_01588 4.2e-52 K Putative DNA-binding domain
HIKPOOAF_01589 3.9e-20 K Putative ATP-dependent DNA helicase recG C-terminal
HIKPOOAF_01590 4.2e-100 mrr L restriction endonuclease
HIKPOOAF_01593 7.6e-54 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
HIKPOOAF_01594 8.9e-178 L Belongs to the 'phage' integrase family
HIKPOOAF_01595 6.1e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
HIKPOOAF_01596 2.4e-266 hsdM 2.1.1.72 V type I restriction-modification system
HIKPOOAF_01597 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HIKPOOAF_01598 6.2e-140 IQ reductase
HIKPOOAF_01599 3.5e-56 yhaI S Protein of unknown function (DUF805)
HIKPOOAF_01600 2.2e-44
HIKPOOAF_01601 2.4e-22
HIKPOOAF_01602 9.1e-12
HIKPOOAF_01603 2.9e-96 K Acetyltransferase (GNAT) domain
HIKPOOAF_01604 1e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HIKPOOAF_01605 3.1e-232 gntT EG Gluconate
HIKPOOAF_01606 4.9e-182 K Transcriptional regulator, LacI family
HIKPOOAF_01607 2.4e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HIKPOOAF_01608 8e-94
HIKPOOAF_01609 2.8e-25
HIKPOOAF_01610 3.7e-61 asp S Asp23 family, cell envelope-related function
HIKPOOAF_01611 6.1e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HIKPOOAF_01613 5.6e-26
HIKPOOAF_01614 2.7e-67 yqkB S Belongs to the HesB IscA family
HIKPOOAF_01615 8.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HIKPOOAF_01616 8.1e-79 F NUDIX domain
HIKPOOAF_01617 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIKPOOAF_01618 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIKPOOAF_01619 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIKPOOAF_01620 2e-163 lacX 5.1.3.3 G Aldose 1-epimerase
HIKPOOAF_01621 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIKPOOAF_01622 2.1e-160 dprA LU DNA protecting protein DprA
HIKPOOAF_01623 5.1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIKPOOAF_01624 1.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIKPOOAF_01625 4.4e-35 yozE S Belongs to the UPF0346 family
HIKPOOAF_01626 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HIKPOOAF_01627 3.7e-168 ypmR E lipolytic protein G-D-S-L family
HIKPOOAF_01628 7.1e-150 DegV S EDD domain protein, DegV family
HIKPOOAF_01629 1.3e-111 hlyIII S protein, hemolysin III
HIKPOOAF_01630 1.6e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIKPOOAF_01631 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIKPOOAF_01632 0.0 yfmR S ABC transporter, ATP-binding protein
HIKPOOAF_01633 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIKPOOAF_01634 2.6e-233 S Tetratricopeptide repeat protein
HIKPOOAF_01635 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIKPOOAF_01636 4.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HIKPOOAF_01637 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HIKPOOAF_01638 1.3e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HIKPOOAF_01639 2.5e-13 M Lysin motif
HIKPOOAF_01640 2.4e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HIKPOOAF_01641 2.6e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
HIKPOOAF_01642 2.1e-100 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIKPOOAF_01643 2.9e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIKPOOAF_01644 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIKPOOAF_01645 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIKPOOAF_01646 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIKPOOAF_01647 9.1e-164 xerD D recombinase XerD
HIKPOOAF_01648 3.5e-168 cvfB S S1 domain
HIKPOOAF_01649 1.4e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HIKPOOAF_01650 0.0 dnaE 2.7.7.7 L DNA polymerase
HIKPOOAF_01651 2e-29 S Protein of unknown function (DUF2929)
HIKPOOAF_01652 1.3e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HIKPOOAF_01653 9.7e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIKPOOAF_01654 4e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
HIKPOOAF_01655 2.4e-220 patA 2.6.1.1 E Aminotransferase
HIKPOOAF_01656 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIKPOOAF_01657 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIKPOOAF_01658 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HIKPOOAF_01659 2.9e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HIKPOOAF_01660 3.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HIKPOOAF_01661 9.6e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIKPOOAF_01662 3.8e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HIKPOOAF_01663 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIKPOOAF_01664 1.1e-181 phoH T phosphate starvation-inducible protein PhoH
HIKPOOAF_01665 1.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIKPOOAF_01666 3.8e-83 bioY S BioY family
HIKPOOAF_01667 7.8e-263 argH 4.3.2.1 E argininosuccinate lyase
HIKPOOAF_01668 5e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HIKPOOAF_01669 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIKPOOAF_01670 8.6e-70 yqeY S YqeY-like protein
HIKPOOAF_01671 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HIKPOOAF_01672 1.1e-262 glnPH2 P ABC transporter permease
HIKPOOAF_01673 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIKPOOAF_01674 3.9e-237 L Transposase
HIKPOOAF_01675 2e-161 L PFAM Integrase catalytic region
HIKPOOAF_01676 2.7e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
HIKPOOAF_01677 3.2e-59 yneR
HIKPOOAF_01678 1.5e-99 qorB 1.6.5.2 GM NmrA-like family
HIKPOOAF_01679 1e-159 akr5f 1.1.1.346 S reductase
HIKPOOAF_01680 1.9e-145 K Transcriptional regulator
HIKPOOAF_01681 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HIKPOOAF_01682 2.3e-155 ypuA S Protein of unknown function (DUF1002)
HIKPOOAF_01683 2.4e-228 aadAT EK Aminotransferase, class I
HIKPOOAF_01684 6.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HIKPOOAF_01685 1.7e-153 tesE Q hydratase
HIKPOOAF_01686 5.1e-95 S Alpha beta hydrolase
HIKPOOAF_01687 2e-07 S Alpha beta hydrolase
HIKPOOAF_01688 5.1e-69 lacA S transferase hexapeptide repeat
HIKPOOAF_01689 5.8e-147 K Transcriptional regulator
HIKPOOAF_01690 8.1e-64 C Flavodoxin
HIKPOOAF_01691 1.4e-10 S Oxidoreductase, aldo keto reductase family protein
HIKPOOAF_01692 2.1e-49 yphJ 4.1.1.44 S decarboxylase
HIKPOOAF_01693 2.4e-10 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HIKPOOAF_01694 2.3e-63 T Transcriptional regulatory protein, C terminal
HIKPOOAF_01695 4.3e-110 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
HIKPOOAF_01696 1.1e-43 XK27_01125 L PFAM IS66 Orf2 family protein
HIKPOOAF_01698 4.1e-98 2.3.1.128 K Acetyltransferase (GNAT) domain
HIKPOOAF_01699 5e-233 lmrB EGP Major facilitator Superfamily
HIKPOOAF_01700 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HIKPOOAF_01701 8.4e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIKPOOAF_01702 1.2e-158 sufD O Uncharacterized protein family (UPF0051)
HIKPOOAF_01703 2e-42 lytE M LysM domain protein
HIKPOOAF_01704 0.0 oppD EP Psort location Cytoplasmic, score
HIKPOOAF_01705 6.8e-82 lytE M LysM domain protein
HIKPOOAF_01706 1.7e-113 xth 3.1.11.2 L exodeoxyribonuclease III
HIKPOOAF_01707 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HIKPOOAF_01708 1.2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
HIKPOOAF_01709 2.6e-152 yeaE S Aldo keto
HIKPOOAF_01710 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
HIKPOOAF_01711 6e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HIKPOOAF_01712 2.5e-77 S Psort location Cytoplasmic, score
HIKPOOAF_01713 2.2e-85 S Short repeat of unknown function (DUF308)
HIKPOOAF_01715 1.1e-43 XK27_01125 L PFAM IS66 Orf2 family protein
HIKPOOAF_01717 5e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HIKPOOAF_01718 1.4e-158 rrmA 2.1.1.187 H Methyltransferase
HIKPOOAF_01719 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIKPOOAF_01720 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HIKPOOAF_01721 1.2e-10 S Protein of unknown function (DUF4044)
HIKPOOAF_01722 1.7e-57
HIKPOOAF_01723 3.1e-77 mraZ K Belongs to the MraZ family
HIKPOOAF_01724 9.8e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIKPOOAF_01725 2.9e-55 ftsL D Cell division protein FtsL
HIKPOOAF_01726 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HIKPOOAF_01727 9.9e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIKPOOAF_01728 4.2e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIKPOOAF_01729 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIKPOOAF_01730 2.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIKPOOAF_01731 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIKPOOAF_01732 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIKPOOAF_01733 2.1e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIKPOOAF_01734 3.2e-40 yggT S YGGT family
HIKPOOAF_01735 2.4e-144 ylmH S S4 domain protein
HIKPOOAF_01736 1.3e-35 divIVA D DivIVA domain protein
HIKPOOAF_01737 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIKPOOAF_01738 4.2e-32 cspA K Cold shock protein
HIKPOOAF_01739 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HIKPOOAF_01741 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIKPOOAF_01742 6e-216 iscS 2.8.1.7 E Aminotransferase class V
HIKPOOAF_01743 7.5e-58 XK27_04120 S Putative amino acid metabolism
HIKPOOAF_01744 6.9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIKPOOAF_01745 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HIKPOOAF_01746 4.9e-117 S Repeat protein
HIKPOOAF_01747 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIKPOOAF_01748 6.9e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIKPOOAF_01749 1.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIKPOOAF_01750 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HIKPOOAF_01751 1.5e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIKPOOAF_01752 7e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIKPOOAF_01753 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIKPOOAF_01754 2.9e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIKPOOAF_01755 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIKPOOAF_01756 7.7e-219 patA 2.6.1.1 E Aminotransferase
HIKPOOAF_01757 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIKPOOAF_01758 8.5e-84 KT Putative sugar diacid recognition
HIKPOOAF_01759 1.1e-218 EG GntP family permease
HIKPOOAF_01760 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HIKPOOAF_01761 2.2e-57
HIKPOOAF_01763 3.8e-130 mltD CBM50 M NlpC P60 family protein
HIKPOOAF_01764 5.7e-29
HIKPOOAF_01765 6.7e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HIKPOOAF_01766 9.8e-32 ykzG S Belongs to the UPF0356 family
HIKPOOAF_01767 4.8e-79
HIKPOOAF_01768 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIKPOOAF_01769 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HIKPOOAF_01770 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HIKPOOAF_01771 1.7e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIKPOOAF_01772 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
HIKPOOAF_01773 3.7e-45 yktA S Belongs to the UPF0223 family
HIKPOOAF_01774 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HIKPOOAF_01775 0.0 typA T GTP-binding protein TypA
HIKPOOAF_01776 2.7e-222 ftsW D Belongs to the SEDS family
HIKPOOAF_01777 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HIKPOOAF_01778 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HIKPOOAF_01779 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIKPOOAF_01780 1.9e-197 ylbL T Belongs to the peptidase S16 family
HIKPOOAF_01781 5.8e-80 comEA L Competence protein ComEA
HIKPOOAF_01782 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
HIKPOOAF_01783 0.0 comEC S Competence protein ComEC
HIKPOOAF_01784 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
HIKPOOAF_01785 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HIKPOOAF_01786 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIKPOOAF_01787 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIKPOOAF_01788 3.5e-163 S Tetratricopeptide repeat
HIKPOOAF_01789 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIKPOOAF_01790 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIKPOOAF_01791 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIKPOOAF_01792 6.1e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HIKPOOAF_01793 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HIKPOOAF_01794 4.9e-08
HIKPOOAF_01795 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIKPOOAF_01796 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIKPOOAF_01797 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIKPOOAF_01798 2.1e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIKPOOAF_01799 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HIKPOOAF_01800 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIKPOOAF_01801 7.3e-88
HIKPOOAF_01802 4.6e-56 sip L Belongs to the 'phage' integrase family
HIKPOOAF_01803 3.7e-08 K Cro/C1-type HTH DNA-binding domain
HIKPOOAF_01804 5e-09 S Helix-turn-helix domain
HIKPOOAF_01805 8.8e-10
HIKPOOAF_01809 2.6e-43 L Bifunctional DNA primase/polymerase, N-terminal
HIKPOOAF_01810 3e-92 S Phage plasmid primase, P4
HIKPOOAF_01812 4.4e-14 S head-tail joining protein
HIKPOOAF_01813 1.2e-23 L HNH endonuclease
HIKPOOAF_01814 1.7e-23 terS L Phage terminase, small subunit
HIKPOOAF_01815 5e-203 terL S overlaps another CDS with the same product name
HIKPOOAF_01816 4.1e-145 S Phage portal protein
HIKPOOAF_01817 6.1e-171 S Caudovirus prohead serine protease
HIKPOOAF_01818 1.6e-19 S Phage gp6-like head-tail connector protein
HIKPOOAF_01819 5.6e-15
HIKPOOAF_01821 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIKPOOAF_01822 2.4e-209 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HIKPOOAF_01823 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIKPOOAF_01824 1.3e-35 ynzC S UPF0291 protein
HIKPOOAF_01825 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HIKPOOAF_01826 4.6e-117 plsC 2.3.1.51 I Acyltransferase
HIKPOOAF_01827 2.7e-140 yabB 2.1.1.223 L Methyltransferase small domain
HIKPOOAF_01828 2.7e-48 yazA L GIY-YIG catalytic domain protein
HIKPOOAF_01829 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIKPOOAF_01830 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HIKPOOAF_01831 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIKPOOAF_01832 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HIKPOOAF_01833 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIKPOOAF_01834 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIKPOOAF_01835 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HIKPOOAF_01836 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HIKPOOAF_01837 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIKPOOAF_01838 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIKPOOAF_01839 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
HIKPOOAF_01840 2.3e-215 nusA K Participates in both transcription termination and antitermination
HIKPOOAF_01841 1e-44 ylxR K Protein of unknown function (DUF448)
HIKPOOAF_01842 1.3e-48 ylxQ J ribosomal protein
HIKPOOAF_01843 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIKPOOAF_01844 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIKPOOAF_01845 7.1e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIKPOOAF_01846 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HIKPOOAF_01847 2.9e-63
HIKPOOAF_01848 3.5e-158 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIKPOOAF_01849 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIKPOOAF_01850 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIKPOOAF_01851 0.0 FbpA K Fibronectin-binding protein
HIKPOOAF_01852 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HIKPOOAF_01853 3.6e-207 carA 6.3.5.5 F Belongs to the CarA family
HIKPOOAF_01854 3.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIKPOOAF_01855 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIKPOOAF_01856 1.5e-65 esbA S Family of unknown function (DUF5322)
HIKPOOAF_01857 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
HIKPOOAF_01858 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HIKPOOAF_01859 3e-81 F Belongs to the NrdI family
HIKPOOAF_01860 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIKPOOAF_01861 2.7e-100 ypsA S Belongs to the UPF0398 family
HIKPOOAF_01862 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIKPOOAF_01863 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HIKPOOAF_01864 3.7e-160 EG EamA-like transporter family
HIKPOOAF_01865 8.1e-123 dnaD L DnaD domain protein
HIKPOOAF_01866 3.8e-85 ypmB S Protein conserved in bacteria
HIKPOOAF_01867 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HIKPOOAF_01868 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HIKPOOAF_01869 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HIKPOOAF_01870 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HIKPOOAF_01871 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIKPOOAF_01872 2.5e-86 S Protein of unknown function (DUF1440)
HIKPOOAF_01873 1.5e-294 L Transposase IS66 family
HIKPOOAF_01874 7.5e-266 G Major Facilitator
HIKPOOAF_01875 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HIKPOOAF_01876 3e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HIKPOOAF_01877 1.4e-270 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HIKPOOAF_01878 3.1e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HIKPOOAF_01879 8.3e-72
HIKPOOAF_01880 1e-73 K Transcriptional regulator, TetR family
HIKPOOAF_01881 4.3e-13 K Transcriptional regulator, TetR family
HIKPOOAF_01882 9.3e-13 steT_1 E amino acid
HIKPOOAF_01884 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIKPOOAF_01885 3.9e-78
HIKPOOAF_01886 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIKPOOAF_01887 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIKPOOAF_01888 4.5e-263 nox C NADH oxidase
HIKPOOAF_01889 3e-87 hmpT S ECF-type riboflavin transporter, S component
HIKPOOAF_01890 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HIKPOOAF_01891 2.3e-167 yvgN C Aldo keto reductase
HIKPOOAF_01892 1.5e-135 puuD S peptidase C26
HIKPOOAF_01893 1.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HIKPOOAF_01894 3.4e-214 yfeO P Voltage gated chloride channel
HIKPOOAF_01895 1.5e-225 sptS 2.7.13.3 T Histidine kinase
HIKPOOAF_01896 3.3e-118 K response regulator
HIKPOOAF_01897 7.4e-88 2.7.6.5 T Region found in RelA / SpoT proteins
HIKPOOAF_01898 4e-73
HIKPOOAF_01899 1.6e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HIKPOOAF_01900 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HIKPOOAF_01901 1.1e-256 malT G Major Facilitator
HIKPOOAF_01902 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
HIKPOOAF_01903 4.3e-172 malR K Transcriptional regulator, LacI family
HIKPOOAF_01904 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HIKPOOAF_01905 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HIKPOOAF_01906 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIKPOOAF_01907 9.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
HIKPOOAF_01908 3.9e-237 L Transposase
HIKPOOAF_01909 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HIKPOOAF_01910 9.3e-166 yniA G Phosphotransferase enzyme family
HIKPOOAF_01911 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIKPOOAF_01912 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIKPOOAF_01913 9.4e-50
HIKPOOAF_01914 1.5e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HIKPOOAF_01915 1.2e-177 prmA J Ribosomal protein L11 methyltransferase
HIKPOOAF_01916 7.5e-58
HIKPOOAF_01917 5.7e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIKPOOAF_01919 1.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HIKPOOAF_01920 2e-274 pipD E Dipeptidase
HIKPOOAF_01921 8.1e-221 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIKPOOAF_01922 3.9e-237 L Transposase
HIKPOOAF_01923 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HIKPOOAF_01924 9.6e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HIKPOOAF_01925 4.3e-227 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIKPOOAF_01926 2e-163 yueF S AI-2E family transporter
HIKPOOAF_01927 7e-30 S dextransucrase activity
HIKPOOAF_01929 4.3e-40 L Transposase
HIKPOOAF_01930 4e-27 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIKPOOAF_01931 2.7e-62 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIKPOOAF_01932 9.3e-51 L Transposase
HIKPOOAF_01933 1.8e-34 secG U Preprotein translocase
HIKPOOAF_01934 3.8e-142 est 3.1.1.1 S Serine aminopeptidase, S33
HIKPOOAF_01935 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIKPOOAF_01936 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HIKPOOAF_01937 1e-102 yxjI
HIKPOOAF_01938 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIKPOOAF_01939 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HIKPOOAF_01940 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HIKPOOAF_01941 6.1e-88 K Acetyltransferase (GNAT) domain
HIKPOOAF_01942 1.3e-75 S PAS domain
HIKPOOAF_01943 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
HIKPOOAF_01944 2e-166 murB 1.3.1.98 M Cell wall formation
HIKPOOAF_01945 8.5e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIKPOOAF_01946 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HIKPOOAF_01947 3.7e-249 fucP G Major Facilitator Superfamily
HIKPOOAF_01948 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIKPOOAF_01949 3.2e-124 ybbR S YbbR-like protein
HIKPOOAF_01950 1.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIKPOOAF_01951 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIKPOOAF_01952 5.6e-52
HIKPOOAF_01953 0.0 oatA I Acyltransferase
HIKPOOAF_01954 1.8e-78 K Transcriptional regulator
HIKPOOAF_01955 1.1e-147 XK27_02985 S Cof-like hydrolase
HIKPOOAF_01956 1.3e-76 lytE M Lysin motif
HIKPOOAF_01958 1.6e-134 K response regulator
HIKPOOAF_01959 5.8e-272 yclK 2.7.13.3 T Histidine kinase
HIKPOOAF_01960 4.1e-153 glcU U sugar transport
HIKPOOAF_01961 2.2e-100 lacA 2.3.1.79 S Transferase hexapeptide repeat
HIKPOOAF_01962 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
HIKPOOAF_01963 1.3e-25
HIKPOOAF_01966 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HIKPOOAF_01967 1.2e-154 KT YcbB domain
HIKPOOAF_01968 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIKPOOAF_01969 3.1e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HIKPOOAF_01970 3.9e-162 EG EamA-like transporter family
HIKPOOAF_01971 6.5e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HIKPOOAF_01972 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HIKPOOAF_01973 0.0 copA 3.6.3.54 P P-type ATPase
HIKPOOAF_01974 3.1e-86
HIKPOOAF_01976 1.8e-56
HIKPOOAF_01977 5.5e-137 yjcE P Sodium proton antiporter
HIKPOOAF_01978 7.4e-45 yjcE P Sodium proton antiporter
HIKPOOAF_01980 1.2e-88
HIKPOOAF_01981 0.0 M domain protein
HIKPOOAF_01982 2.9e-186 M domain protein
HIKPOOAF_01983 2.5e-32
HIKPOOAF_01984 8.2e-185 ampC V Beta-lactamase
HIKPOOAF_01985 4.4e-217 arcA 3.5.3.6 E Arginine
HIKPOOAF_01986 2.7e-79 argR K Regulates arginine biosynthesis genes
HIKPOOAF_01987 1.1e-259 E Arginine ornithine antiporter
HIKPOOAF_01988 1.4e-222 arcD U Amino acid permease
HIKPOOAF_01989 3e-10
HIKPOOAF_01990 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HIKPOOAF_01991 1.7e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HIKPOOAF_01992 6e-108 tdk 2.7.1.21 F thymidine kinase
HIKPOOAF_01993 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIKPOOAF_01994 6.1e-165 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIKPOOAF_01995 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIKPOOAF_01996 3.9e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIKPOOAF_01997 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIKPOOAF_01998 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIKPOOAF_01999 1.3e-191 yibE S overlaps another CDS with the same product name
HIKPOOAF_02000 4.4e-130 yibF S overlaps another CDS with the same product name
HIKPOOAF_02001 5e-232 pyrP F Permease
HIKPOOAF_02002 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HIKPOOAF_02003 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIKPOOAF_02004 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIKPOOAF_02005 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIKPOOAF_02006 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIKPOOAF_02007 4.8e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIKPOOAF_02008 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIKPOOAF_02009 3.8e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HIKPOOAF_02010 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HIKPOOAF_02011 3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIKPOOAF_02012 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HIKPOOAF_02013 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HIKPOOAF_02014 1e-31 S Protein of unknown function (DUF2969)
HIKPOOAF_02015 1.1e-220 rodA D Belongs to the SEDS family
HIKPOOAF_02016 1.4e-47 gcvH E glycine cleavage
HIKPOOAF_02017 5e-215 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HIKPOOAF_02018 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HIKPOOAF_02019 1.2e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HIKPOOAF_02020 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HIKPOOAF_02021 1.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HIKPOOAF_02022 4.8e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HIKPOOAF_02023 1.1e-49 maa 2.3.1.79 S Maltose O-acetyltransferase
HIKPOOAF_02024 9.2e-29 maa 2.3.1.79 S Maltose O-acetyltransferase
HIKPOOAF_02025 5.1e-156 ytbE 1.1.1.346 S Aldo keto reductase
HIKPOOAF_02026 4.2e-203 araR K Transcriptional regulator
HIKPOOAF_02027 4.3e-83 usp6 T universal stress protein
HIKPOOAF_02028 4.4e-46
HIKPOOAF_02029 1.8e-240 rarA L recombination factor protein RarA
HIKPOOAF_02030 3.5e-85 yueI S Protein of unknown function (DUF1694)
HIKPOOAF_02031 1.3e-20
HIKPOOAF_02032 8.1e-75 4.4.1.5 E Glyoxalase
HIKPOOAF_02033 2.5e-138 S Membrane
HIKPOOAF_02034 2.9e-139 S Belongs to the UPF0246 family
HIKPOOAF_02035 1.9e-184 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HIKPOOAF_02036 9.5e-25 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HIKPOOAF_02037 1.7e-31 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HIKPOOAF_02039 1.4e-18 L Transposase IS66 family
HIKPOOAF_02040 8.6e-47 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
HIKPOOAF_02041 3e-46 L Transposase IS66 family
HIKPOOAF_02042 2.4e-26 tra L Transposase and inactivated derivatives, IS30 family
HIKPOOAF_02043 1.7e-290 clcA P chloride
HIKPOOAF_02044 1.2e-244 yifK E Amino acid permease
HIKPOOAF_02045 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIKPOOAF_02046 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIKPOOAF_02047 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HIKPOOAF_02048 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIKPOOAF_02050 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIKPOOAF_02052 2.5e-33 L PFAM Integrase catalytic region
HIKPOOAF_02053 4.3e-13
HIKPOOAF_02054 2.8e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HIKPOOAF_02055 1.4e-83 ltrA S Bacterial low temperature requirement A protein (LtrA)
HIKPOOAF_02057 1.5e-52 ywiB S Domain of unknown function (DUF1934)
HIKPOOAF_02058 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIKPOOAF_02059 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIKPOOAF_02060 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIKPOOAF_02061 4.6e-41 rpmE2 J Ribosomal protein L31
HIKPOOAF_02062 4.5e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIKPOOAF_02063 2.8e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HIKPOOAF_02064 1.6e-115 srtA 3.4.22.70 M sortase family
HIKPOOAF_02065 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HIKPOOAF_02066 1.4e-158 3.2.1.55 GH51 G Right handed beta helix region
HIKPOOAF_02067 5.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIKPOOAF_02068 2.9e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HIKPOOAF_02069 4.6e-120 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HIKPOOAF_02070 8.9e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIKPOOAF_02071 2e-92 lemA S LemA family
HIKPOOAF_02072 2e-158 htpX O Belongs to the peptidase M48B family
HIKPOOAF_02073 9.5e-39 S Cytochrome B5
HIKPOOAF_02074 1.3e-202 amtB P ammonium transporter
HIKPOOAF_02075 5.7e-247 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HIKPOOAF_02076 4.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIKPOOAF_02077 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HIKPOOAF_02078 3.8e-25 S dextransucrase activity
HIKPOOAF_02079 1.4e-41 S Acyltransferase family
HIKPOOAF_02080 2.7e-38 M Peptidase_C39 like family
HIKPOOAF_02081 3e-83 S Psort location CytoplasmicMembrane, score
HIKPOOAF_02082 1.1e-108 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIKPOOAF_02083 3.7e-134 M Glycosyltransferase like family 2
HIKPOOAF_02084 1.3e-25
HIKPOOAF_02085 7.4e-116 M repeat protein
HIKPOOAF_02086 4.1e-135 3.2.1.96, 3.5.1.28 GH73 M repeat protein
HIKPOOAF_02087 1.2e-51 M KxYKxGKxW signal domain protein
HIKPOOAF_02088 7.8e-118 L Transposase, IS116 IS110 IS902 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)