ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMPBNJCG_00005 5.5e-139 mreC M Involved in formation and maintenance of cell shape
HMPBNJCG_00006 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HMPBNJCG_00007 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
HMPBNJCG_00008 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMPBNJCG_00009 2.9e-218 araT 2.6.1.1 E Aminotransferase
HMPBNJCG_00010 2.6e-143 recO L Involved in DNA repair and RecF pathway recombination
HMPBNJCG_00011 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMPBNJCG_00012 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMPBNJCG_00013 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMPBNJCG_00014 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMPBNJCG_00015 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMPBNJCG_00016 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMPBNJCG_00017 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMPBNJCG_00018 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMPBNJCG_00019 6.1e-79 L transposase activity
HMPBNJCG_00020 1.3e-49 L transposition
HMPBNJCG_00021 6.3e-34 L Integrase core domain protein
HMPBNJCG_00022 2.3e-161 S CHAP domain
HMPBNJCG_00023 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
HMPBNJCG_00024 3.8e-70 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMPBNJCG_00025 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMPBNJCG_00026 9.2e-141 1.1.1.169 H Ketopantoate reductase
HMPBNJCG_00027 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMPBNJCG_00028 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HMPBNJCG_00029 1.2e-09 L Transposase
HMPBNJCG_00030 7.8e-211 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMPBNJCG_00031 8.3e-221 nodC 2.4.1.212 GT2 M Chitin synthase
HMPBNJCG_00032 6.5e-54 L transposition
HMPBNJCG_00033 7.7e-19 L transposase activity
HMPBNJCG_00034 2.5e-40 L Transposase
HMPBNJCG_00035 0.0 3.6.3.8 P cation transport ATPase
HMPBNJCG_00036 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HMPBNJCG_00037 1.9e-105 V Abi-like protein
HMPBNJCG_00039 2.3e-12
HMPBNJCG_00041 2e-296 S DNA primase
HMPBNJCG_00042 3e-164 KL Phage plasmid primase P4 family
HMPBNJCG_00043 2.4e-22
HMPBNJCG_00044 1.2e-14
HMPBNJCG_00048 1.8e-19 K Cro/C1-type HTH DNA-binding domain
HMPBNJCG_00049 1e-21 xre K transcriptional
HMPBNJCG_00050 6.9e-220 sip L Belongs to the 'phage' integrase family
HMPBNJCG_00052 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMPBNJCG_00053 7.3e-166 metF 1.5.1.20 E reductase
HMPBNJCG_00054 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HMPBNJCG_00055 1.7e-94 panT S ECF transporter, substrate-specific component
HMPBNJCG_00056 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMPBNJCG_00057 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HMPBNJCG_00058 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMPBNJCG_00059 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPBNJCG_00060 2.8e-40 T PhoQ Sensor
HMPBNJCG_00061 1.7e-43 T PhoQ Sensor
HMPBNJCG_00062 5.8e-79 T PhoQ Sensor
HMPBNJCG_00063 2.1e-30 rpsT J rRNA binding
HMPBNJCG_00064 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
HMPBNJCG_00065 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
HMPBNJCG_00066 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HMPBNJCG_00067 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HMPBNJCG_00068 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMPBNJCG_00069 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMPBNJCG_00070 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMPBNJCG_00071 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HMPBNJCG_00072 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HMPBNJCG_00073 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
HMPBNJCG_00074 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMPBNJCG_00075 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HMPBNJCG_00076 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMPBNJCG_00077 3.1e-81 ypmB S Protein conserved in bacteria
HMPBNJCG_00078 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HMPBNJCG_00079 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HMPBNJCG_00080 1.5e-07
HMPBNJCG_00081 3e-13
HMPBNJCG_00082 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HMPBNJCG_00083 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HMPBNJCG_00084 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HMPBNJCG_00085 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HMPBNJCG_00086 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HMPBNJCG_00087 4.2e-18 D nuclear chromosome segregation
HMPBNJCG_00088 1.5e-135 yejC S cyclic nucleotide-binding protein
HMPBNJCG_00089 1.2e-163 rapZ S Displays ATPase and GTPase activities
HMPBNJCG_00090 1.8e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMPBNJCG_00091 8.7e-162 whiA K May be required for sporulation
HMPBNJCG_00092 8e-90 pepD E Dipeptidase
HMPBNJCG_00093 5.8e-41 pepD E dipeptidase activity
HMPBNJCG_00094 5.4e-32 cspD K Cold shock protein domain
HMPBNJCG_00095 9.4e-43 K Cold-Shock Protein
HMPBNJCG_00096 3.3e-222 L Transposase
HMPBNJCG_00097 0.0 copB 3.6.3.4 P P-type ATPase
HMPBNJCG_00098 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMPBNJCG_00099 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMPBNJCG_00100 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HMPBNJCG_00101 4.8e-157 glcU U Glucose uptake
HMPBNJCG_00102 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
HMPBNJCG_00103 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
HMPBNJCG_00104 2.2e-101 XK27_10720 D peptidase activity
HMPBNJCG_00105 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
HMPBNJCG_00106 1.7e-08
HMPBNJCG_00108 1.2e-172 yeiH S Membrane
HMPBNJCG_00109 5.5e-119 mur1 NU muramidase
HMPBNJCG_00110 1.9e-83 L transposition
HMPBNJCG_00111 2.6e-166 cpsY K Transcriptional regulator
HMPBNJCG_00112 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMPBNJCG_00113 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
HMPBNJCG_00114 2e-104 artQ P ABC transporter (Permease
HMPBNJCG_00115 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPBNJCG_00116 1.1e-158 aatB ET ABC transporter substrate-binding protein
HMPBNJCG_00117 3.5e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMPBNJCG_00118 2.5e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMPBNJCG_00119 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
HMPBNJCG_00120 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
HMPBNJCG_00121 9.3e-20 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
HMPBNJCG_00122 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMPBNJCG_00123 4.5e-126 gntR1 K transcriptional
HMPBNJCG_00124 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMPBNJCG_00125 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMPBNJCG_00126 4.1e-87 niaX
HMPBNJCG_00127 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
HMPBNJCG_00128 6.9e-127 K DNA-binding helix-turn-helix protein
HMPBNJCG_00129 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMPBNJCG_00130 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMPBNJCG_00131 4.1e-167 GK ROK family
HMPBNJCG_00132 8.3e-159 dprA LU DNA protecting protein DprA
HMPBNJCG_00133 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMPBNJCG_00134 1.4e-150 S TraX protein
HMPBNJCG_00135 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPBNJCG_00136 2.4e-251 T PhoQ Sensor
HMPBNJCG_00137 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMPBNJCG_00138 1.1e-152 XK27_05470 E Methionine synthase
HMPBNJCG_00139 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HMPBNJCG_00140 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMPBNJCG_00141 1.8e-51 IQ Acetoin reductase
HMPBNJCG_00142 3.9e-19 IQ Acetoin reductase
HMPBNJCG_00143 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMPBNJCG_00144 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HMPBNJCG_00147 1.3e-212 pqqE C radical SAM domain protein
HMPBNJCG_00148 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
HMPBNJCG_00149 6.6e-61 EGP Major facilitator Superfamily
HMPBNJCG_00150 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMPBNJCG_00151 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HMPBNJCG_00152 8.6e-196 L Transposase
HMPBNJCG_00153 6.4e-104 V ABC transporter (Permease
HMPBNJCG_00154 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMPBNJCG_00155 1.6e-10
HMPBNJCG_00156 1.2e-97 K Transcriptional regulator, TetR family
HMPBNJCG_00157 1.2e-158 czcD P cation diffusion facilitator family transporter
HMPBNJCG_00158 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HMPBNJCG_00159 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HMPBNJCG_00160 6e-08 S Hydrolases of the alpha beta superfamily
HMPBNJCG_00161 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
HMPBNJCG_00162 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
HMPBNJCG_00163 7.6e-134 5.1.3.2 GM Psort location CytoplasmicMembrane, score
HMPBNJCG_00164 4.1e-143
HMPBNJCG_00165 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HMPBNJCG_00166 7.6e-160 pelF GT4 M Domain of unknown function (DUF3492)
HMPBNJCG_00167 1.9e-109 pelF GT4 M Domain of unknown function (DUF3492)
HMPBNJCG_00168 6.8e-185 pelG M Putative exopolysaccharide Exporter (EPS-E)
HMPBNJCG_00169 1.5e-211 cotH M CotH kinase protein
HMPBNJCG_00170 8.4e-53 G Domain of unknown function (DUF4832)
HMPBNJCG_00171 4.9e-21 G Domain of unknown function (DUF4832)
HMPBNJCG_00172 3.7e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMPBNJCG_00174 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMPBNJCG_00175 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
HMPBNJCG_00176 1.4e-124 endA F DNA RNA non-specific endonuclease
HMPBNJCG_00177 4.2e-110 tcyB_2 P ABC transporter (permease)
HMPBNJCG_00178 8e-115 gltJ P ABC transporter (Permease
HMPBNJCG_00179 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMPBNJCG_00180 1e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPBNJCG_00181 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPBNJCG_00182 1.5e-247 vicK 2.7.13.3 T Histidine kinase
HMPBNJCG_00183 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HMPBNJCG_00184 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HMPBNJCG_00185 9.2e-147 yidA S hydrolases of the HAD superfamily
HMPBNJCG_00186 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
HMPBNJCG_00187 2.6e-67 ywiB S Domain of unknown function (DUF1934)
HMPBNJCG_00188 0.0 pacL 3.6.3.8 P cation transport ATPase
HMPBNJCG_00189 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMPBNJCG_00190 4.3e-180 yjjH S Calcineurin-like phosphoesterase
HMPBNJCG_00191 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMPBNJCG_00192 1.8e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMPBNJCG_00193 2.5e-124 ftsE D cell division ATP-binding protein FtsE
HMPBNJCG_00194 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HMPBNJCG_00195 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HMPBNJCG_00196 1.1e-175 yubA S permease
HMPBNJCG_00197 4.9e-224 G COG0457 FOG TPR repeat
HMPBNJCG_00198 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMPBNJCG_00199 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMPBNJCG_00200 2.9e-90 ebsA S Family of unknown function (DUF5322)
HMPBNJCG_00201 3.9e-15 M LysM domain
HMPBNJCG_00202 2.8e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMPBNJCG_00203 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMPBNJCG_00204 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMPBNJCG_00205 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMPBNJCG_00206 9.1e-10 L COG1943 Transposase and inactivated derivatives
HMPBNJCG_00207 6.9e-86 XK27_03610 K Gnat family
HMPBNJCG_00208 3.2e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMPBNJCG_00209 2.4e-275 pepV 3.5.1.18 E Dipeptidase
HMPBNJCG_00210 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMPBNJCG_00211 4e-21 V Glucan-binding protein C
HMPBNJCG_00213 6.6e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMPBNJCG_00214 9.3e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMPBNJCG_00215 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HMPBNJCG_00216 3.8e-42 clcA_2 P chloride channel
HMPBNJCG_00217 3.6e-40 clcA_2 P chloride
HMPBNJCG_00218 2.5e-43 yfeJ 6.3.5.2 F glutamine amidotransferase
HMPBNJCG_00219 1.7e-48 yfeJ 6.3.5.2 F glutamine amidotransferase
HMPBNJCG_00220 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HMPBNJCG_00221 3.8e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HMPBNJCG_00222 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HMPBNJCG_00223 2.6e-105 cps4C M biosynthesis protein
HMPBNJCG_00224 5.3e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
HMPBNJCG_00225 5.7e-250 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HMPBNJCG_00226 8.5e-23 rgpAc GT4 M group 1 family protein
HMPBNJCG_00227 1.7e-27 tnp L DDE domain
HMPBNJCG_00228 2.2e-22 L Transposase
HMPBNJCG_00229 3e-139 L Integrase core domain
HMPBNJCG_00230 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
HMPBNJCG_00233 2.6e-143 2.4.2.3 F Phosphorylase superfamily
HMPBNJCG_00234 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HMPBNJCG_00235 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
HMPBNJCG_00236 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
HMPBNJCG_00237 6.6e-73 dinF V Mate efflux family protein
HMPBNJCG_00238 4.8e-41 dinF V Mate efflux family protein
HMPBNJCG_00240 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HMPBNJCG_00241 3.7e-190
HMPBNJCG_00242 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
HMPBNJCG_00243 3.5e-28 3.4.13.21 I Protein conserved in bacteria
HMPBNJCG_00245 5.7e-118 S TraX protein
HMPBNJCG_00246 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HMPBNJCG_00247 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HMPBNJCG_00248 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMPBNJCG_00249 4.7e-143 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMPBNJCG_00250 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMPBNJCG_00251 6.8e-133 cas6 S Pfam:DUF2276
HMPBNJCG_00252 0.0 csm1 S CRISPR-associated protein Csm1 family
HMPBNJCG_00253 5.6e-62 csm2 L Pfam:DUF310
HMPBNJCG_00254 1.1e-116 csm3 L RAMP superfamily
HMPBNJCG_00255 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
HMPBNJCG_00256 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
HMPBNJCG_00257 2.1e-14 csm6 S Psort location Cytoplasmic, score
HMPBNJCG_00258 5.2e-74 csm6 S Psort location Cytoplasmic, score
HMPBNJCG_00259 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMPBNJCG_00260 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMPBNJCG_00261 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
HMPBNJCG_00263 2.5e-267 dtpT E transporter
HMPBNJCG_00264 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
HMPBNJCG_00265 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
HMPBNJCG_00266 1.8e-67 yecS P ABC transporter (Permease
HMPBNJCG_00268 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HMPBNJCG_00269 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
HMPBNJCG_00270 5.4e-104 yfiF3 K sequence-specific DNA binding
HMPBNJCG_00271 1.9e-147 L Transposase
HMPBNJCG_00272 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMPBNJCG_00273 1.8e-240 agcS E (Alanine) symporter
HMPBNJCG_00274 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMPBNJCG_00275 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
HMPBNJCG_00276 1.8e-59 Q phosphatase activity
HMPBNJCG_00277 9.3e-62 S haloacid dehalogenase-like hydrolase
HMPBNJCG_00278 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMPBNJCG_00279 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HMPBNJCG_00280 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
HMPBNJCG_00281 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
HMPBNJCG_00282 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMPBNJCG_00283 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMPBNJCG_00284 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMPBNJCG_00285 1.9e-43 yktA S Belongs to the UPF0223 family
HMPBNJCG_00286 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HMPBNJCG_00287 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HMPBNJCG_00288 3.3e-158 pstS P phosphate
HMPBNJCG_00289 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
HMPBNJCG_00290 2e-155 pstA P phosphate transport system permease
HMPBNJCG_00291 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMPBNJCG_00292 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMPBNJCG_00293 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
HMPBNJCG_00294 0.0 pepN 3.4.11.2 E aminopeptidase
HMPBNJCG_00295 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HMPBNJCG_00296 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
HMPBNJCG_00297 1.1e-17
HMPBNJCG_00298 3.7e-09
HMPBNJCG_00299 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMPBNJCG_00300 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HMPBNJCG_00301 2.3e-23 L Transposase
HMPBNJCG_00302 4.6e-25 tatA U protein secretion
HMPBNJCG_00303 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMPBNJCG_00304 1.1e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HMPBNJCG_00305 5.6e-233 ycdB P peroxidase
HMPBNJCG_00306 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
HMPBNJCG_00307 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00308 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00309 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00310 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00311 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00312 1.9e-37 3.5.1.28 NU amidase activity
HMPBNJCG_00313 8.5e-266 3.5.1.28 NU amidase activity
HMPBNJCG_00314 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HMPBNJCG_00315 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HMPBNJCG_00316 0.0 lpdA 1.8.1.4 C Dehydrogenase
HMPBNJCG_00317 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMPBNJCG_00318 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMPBNJCG_00319 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HMPBNJCG_00320 5e-38 P membrane protein (DUF2207)
HMPBNJCG_00321 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
HMPBNJCG_00322 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMPBNJCG_00323 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMPBNJCG_00324 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMPBNJCG_00325 1.2e-157 rssA S Phospholipase, patatin family
HMPBNJCG_00326 3.9e-78 estA E GDSL-like protein
HMPBNJCG_00327 2.6e-15 estA E Lysophospholipase L1 and related esterases
HMPBNJCG_00328 3.7e-293 S unusual protein kinase
HMPBNJCG_00329 4.9e-39 S granule-associated protein
HMPBNJCG_00330 7.9e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMPBNJCG_00331 5.8e-28 bglH 3.2.1.86 GT1 G beta-glucosidase activity
HMPBNJCG_00332 1.3e-199 S hmm pf01594
HMPBNJCG_00333 1.6e-44 G alpha-ribazole phosphatase activity
HMPBNJCG_00334 2e-33 G Belongs to the phosphoglycerate mutase family
HMPBNJCG_00335 1.1e-25 G Belongs to the phosphoglycerate mutase family
HMPBNJCG_00336 8.8e-66 pgm G Belongs to the phosphoglycerate mutase family
HMPBNJCG_00337 1.7e-80 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HMPBNJCG_00338 4.9e-94 V VanZ like family
HMPBNJCG_00339 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMPBNJCG_00340 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMPBNJCG_00341 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMPBNJCG_00342 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HMPBNJCG_00343 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMPBNJCG_00344 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
HMPBNJCG_00346 7.7e-35
HMPBNJCG_00349 7.8e-202 S Phage integrase family
HMPBNJCG_00351 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMPBNJCG_00352 4.3e-133 XK27_05110 P chloride
HMPBNJCG_00353 1.2e-61 XK27_05110 P chloride
HMPBNJCG_00354 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HMPBNJCG_00355 1.3e-282 clcA P Chloride transporter, ClC family
HMPBNJCG_00356 6.7e-75 fld C Flavodoxin
HMPBNJCG_00358 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
HMPBNJCG_00359 3.5e-151 estA CE1 S Putative esterase
HMPBNJCG_00360 1e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMPBNJCG_00361 1.2e-135 XK27_08845 S abc transporter atp-binding protein
HMPBNJCG_00362 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HMPBNJCG_00363 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
HMPBNJCG_00364 3.2e-17 S Domain of unknown function (DUF4649)
HMPBNJCG_00366 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
HMPBNJCG_00367 1.1e-22 Q the current gene model (or a revised gene model) may contain a frame shift
HMPBNJCG_00368 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
HMPBNJCG_00371 1.3e-57 T Toxic component of a toxin-antitoxin (TA) module
HMPBNJCG_00373 8.2e-70 argR K Regulates arginine biosynthesis genes
HMPBNJCG_00374 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HMPBNJCG_00375 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMPBNJCG_00376 7e-34 S Protein of unknown function (DUF3021)
HMPBNJCG_00377 1.2e-61 KT phosphorelay signal transduction system
HMPBNJCG_00379 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMPBNJCG_00381 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMPBNJCG_00382 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HMPBNJCG_00383 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
HMPBNJCG_00384 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMPBNJCG_00385 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HMPBNJCG_00386 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMPBNJCG_00387 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMPBNJCG_00388 0.0 dnaE 2.7.7.7 L DNA polymerase
HMPBNJCG_00389 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
HMPBNJCG_00390 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMPBNJCG_00391 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMPBNJCG_00392 2.5e-43 ysdA L Membrane
HMPBNJCG_00393 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMPBNJCG_00394 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMPBNJCG_00395 3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMPBNJCG_00396 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HMPBNJCG_00398 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMPBNJCG_00399 1.7e-83 ypmS S Protein conserved in bacteria
HMPBNJCG_00400 6e-144 ypmR E lipolytic protein G-D-S-L family
HMPBNJCG_00401 1e-148 DegV S DegV family
HMPBNJCG_00402 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
HMPBNJCG_00403 1.8e-72 argR K Regulates arginine biosynthesis genes
HMPBNJCG_00404 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMPBNJCG_00405 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMPBNJCG_00406 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
HMPBNJCG_00407 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMPBNJCG_00410 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMPBNJCG_00411 2.9e-125 dnaD
HMPBNJCG_00412 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMPBNJCG_00413 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMPBNJCG_00414 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HMPBNJCG_00415 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMPBNJCG_00416 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMPBNJCG_00417 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HMPBNJCG_00418 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMPBNJCG_00419 1.6e-239 rodA D Belongs to the SEDS family
HMPBNJCG_00420 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HMPBNJCG_00421 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMPBNJCG_00422 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMPBNJCG_00423 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMPBNJCG_00424 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMPBNJCG_00425 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HMPBNJCG_00426 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMPBNJCG_00427 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMPBNJCG_00428 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMPBNJCG_00429 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMPBNJCG_00431 4.2e-86 L Integrase core domain protein
HMPBNJCG_00432 1.1e-53 L transposition
HMPBNJCG_00433 8.2e-22 L Transposase
HMPBNJCG_00434 5.2e-36 L transposase activity
HMPBNJCG_00435 1.3e-22 XK27_08085
HMPBNJCG_00436 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HMPBNJCG_00437 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HMPBNJCG_00438 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HMPBNJCG_00439 1.1e-121 ylfI S tigr01906
HMPBNJCG_00440 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMPBNJCG_00441 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
HMPBNJCG_00442 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HMPBNJCG_00445 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMPBNJCG_00446 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMPBNJCG_00447 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMPBNJCG_00448 1.1e-206 yurR 1.4.5.1 E oxidoreductase
HMPBNJCG_00449 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
HMPBNJCG_00450 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMPBNJCG_00451 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMPBNJCG_00452 1.7e-70 gtrA S GtrA-like protein
HMPBNJCG_00453 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMPBNJCG_00454 6e-169 ybbR S Protein conserved in bacteria
HMPBNJCG_00455 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMPBNJCG_00456 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HMPBNJCG_00457 8.7e-150 cobQ S glutamine amidotransferase
HMPBNJCG_00458 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMPBNJCG_00459 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
HMPBNJCG_00460 0.0 uup S abc transporter atp-binding protein
HMPBNJCG_00461 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HMPBNJCG_00462 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMPBNJCG_00463 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMPBNJCG_00464 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HMPBNJCG_00465 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMPBNJCG_00466 7.9e-39 ptsH G phosphocarrier protein Hpr
HMPBNJCG_00467 3.3e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
HMPBNJCG_00468 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
HMPBNJCG_00469 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HMPBNJCG_00470 2.2e-34 nrdH O Glutaredoxin
HMPBNJCG_00471 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMPBNJCG_00472 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMPBNJCG_00474 4.2e-71 L Transposase (IS116 IS110 IS902 family)
HMPBNJCG_00475 3.3e-26 L Transposase (IS116 IS110 IS902 family)
HMPBNJCG_00476 1.2e-164 ypuA S secreted protein
HMPBNJCG_00477 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
HMPBNJCG_00478 5.1e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HMPBNJCG_00479 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMPBNJCG_00480 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMPBNJCG_00481 3.4e-258 noxE P NADH oxidase
HMPBNJCG_00482 1.9e-294 yfmM S abc transporter atp-binding protein
HMPBNJCG_00483 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
HMPBNJCG_00484 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HMPBNJCG_00485 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HMPBNJCG_00486 2e-86 S ECF-type riboflavin transporter, S component
HMPBNJCG_00488 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMPBNJCG_00489 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HMPBNJCG_00492 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMPBNJCG_00493 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMPBNJCG_00494 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMPBNJCG_00495 0.0 smc D Required for chromosome condensation and partitioning
HMPBNJCG_00496 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMPBNJCG_00497 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMPBNJCG_00498 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMPBNJCG_00499 2.4e-92 pat 2.3.1.183 M acetyltransferase
HMPBNJCG_00500 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMPBNJCG_00501 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMPBNJCG_00502 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HMPBNJCG_00503 1.2e-62 bioY S biotin transmembrane transporter activity
HMPBNJCG_00504 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
HMPBNJCG_00505 1.5e-138 proV E abc transporter atp-binding protein
HMPBNJCG_00506 4.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
HMPBNJCG_00507 3e-111 proWZ P ABC transporter (Permease
HMPBNJCG_00508 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
HMPBNJCG_00509 1.6e-205 S Protein of unknown function (DUF917)
HMPBNJCG_00510 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HMPBNJCG_00511 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
HMPBNJCG_00512 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMPBNJCG_00513 1.5e-192 desK 2.7.13.3 T Histidine kinase
HMPBNJCG_00514 1.4e-133 yvfS V ABC-2 type transporter
HMPBNJCG_00515 8.7e-159 XK27_09825 V abc transporter atp-binding protein
HMPBNJCG_00518 8.1e-163 yocS S Transporter
HMPBNJCG_00519 1.2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HMPBNJCG_00520 7.5e-115 yvfS V Transporter
HMPBNJCG_00521 3.9e-151 XK27_09825 V abc transporter atp-binding protein
HMPBNJCG_00522 2.7e-14 liaI KT membrane
HMPBNJCG_00523 2.6e-30 liaI KT membrane
HMPBNJCG_00524 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
HMPBNJCG_00525 0.0 V ABC transporter (permease)
HMPBNJCG_00526 1.9e-133 macB2 V ABC transporter, ATP-binding protein
HMPBNJCG_00527 3.1e-165 T Histidine kinase
HMPBNJCG_00528 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPBNJCG_00529 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMPBNJCG_00530 3.3e-69 pbuX F xanthine permease
HMPBNJCG_00531 9.2e-119 pbuX F xanthine permease
HMPBNJCG_00532 1.5e-247 norM V Multidrug efflux pump
HMPBNJCG_00533 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMPBNJCG_00534 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
HMPBNJCG_00535 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMPBNJCG_00536 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMPBNJCG_00537 4.8e-25 csbD K CsbD-like
HMPBNJCG_00538 6.2e-228 yfnA E amino acid
HMPBNJCG_00539 5.1e-110 XK27_02070 S nitroreductase
HMPBNJCG_00540 9.5e-150 1.13.11.2 S glyoxalase
HMPBNJCG_00541 5.6e-77 ywnA K Transcriptional regulator
HMPBNJCG_00542 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
HMPBNJCG_00543 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMPBNJCG_00544 1.4e-110 drgA C Nitroreductase
HMPBNJCG_00545 3e-102 yoaK S Protein of unknown function (DUF1275)
HMPBNJCG_00547 6.8e-161 yvgN C reductase
HMPBNJCG_00548 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMPBNJCG_00549 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
HMPBNJCG_00551 1.1e-37 BP1961 P nitric oxide dioxygenase activity
HMPBNJCG_00552 1.4e-54 K response regulator
HMPBNJCG_00553 9.3e-72 S Signal peptide protein, YSIRK family
HMPBNJCG_00555 4.5e-61
HMPBNJCG_00556 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMPBNJCG_00557 1e-137
HMPBNJCG_00558 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
HMPBNJCG_00559 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
HMPBNJCG_00560 5.8e-109 MA20_06410 E LysE type translocator
HMPBNJCG_00561 5.6e-08
HMPBNJCG_00562 2.7e-09
HMPBNJCG_00563 0.0 M family 8
HMPBNJCG_00565 1.5e-162 hrtB V MacB-like periplasmic core domain
HMPBNJCG_00566 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
HMPBNJCG_00567 1.1e-151 V MatE
HMPBNJCG_00569 3.9e-110 C Fe-S oxidoreductases
HMPBNJCG_00570 1.2e-176 EGP Major Facilitator Superfamily
HMPBNJCG_00571 5.5e-258 I radical SAM domain protein
HMPBNJCG_00573 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HMPBNJCG_00574 1.4e-150 L Integrase core domain protein
HMPBNJCG_00575 1.8e-87 L transposase activity
HMPBNJCG_00577 2.8e-85
HMPBNJCG_00578 0.0 sbcC L ATPase involved in DNA repair
HMPBNJCG_00579 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMPBNJCG_00580 0.0 lacL 3.2.1.23 G -beta-galactosidase
HMPBNJCG_00581 0.0 lacS G transporter
HMPBNJCG_00582 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMPBNJCG_00583 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMPBNJCG_00584 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HMPBNJCG_00585 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMPBNJCG_00586 2.3e-184 galR K Transcriptional regulator
HMPBNJCG_00587 2.7e-08 L Integrase core domain protein
HMPBNJCG_00588 1.2e-25 L transposition
HMPBNJCG_00589 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HMPBNJCG_00590 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HMPBNJCG_00591 2.5e-101 V abc transporter atp-binding protein
HMPBNJCG_00592 4.3e-40 V abc transporter atp-binding protein
HMPBNJCG_00593 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HMPBNJCG_00594 6.4e-62 L Transposase
HMPBNJCG_00595 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00596 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00597 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00598 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMPBNJCG_00599 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HMPBNJCG_00600 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMPBNJCG_00601 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMPBNJCG_00604 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMPBNJCG_00605 5.8e-175 vraS 2.7.13.3 T Histidine kinase
HMPBNJCG_00606 3.7e-120 yvqF KT membrane
HMPBNJCG_00607 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HMPBNJCG_00608 2e-132 stp 3.1.3.16 T phosphatase
HMPBNJCG_00609 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMPBNJCG_00610 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMPBNJCG_00611 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMPBNJCG_00612 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HMPBNJCG_00613 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMPBNJCG_00614 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMPBNJCG_00615 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
HMPBNJCG_00616 2.1e-148 supH S overlaps another CDS with the same product name
HMPBNJCG_00617 8.6e-63 yvoA_1 K Transcriptional
HMPBNJCG_00618 2.8e-120 skfE V abc transporter atp-binding protein
HMPBNJCG_00619 3.3e-133 V ATPase activity
HMPBNJCG_00620 4.3e-172 oppF P Belongs to the ABC transporter superfamily
HMPBNJCG_00621 2.2e-204 oppD P Belongs to the ABC transporter superfamily
HMPBNJCG_00622 4.9e-168 amiD P ABC transporter (Permease
HMPBNJCG_00623 4.2e-278 amiC P ABC transporter (Permease
HMPBNJCG_00624 3.7e-140 amiA E ABC transporter, substrate-binding protein, family 5
HMPBNJCG_00625 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HMPBNJCG_00626 8.1e-45 L Transposase
HMPBNJCG_00627 4.1e-158 L COG2801 Transposase and inactivated derivatives
HMPBNJCG_00628 1.2e-24 oppF P Belongs to the ABC transporter superfamily
HMPBNJCG_00629 3.8e-45 oppF P Belongs to the ABC transporter superfamily
HMPBNJCG_00630 1.4e-40 tatD L Hydrolase, tatd
HMPBNJCG_00631 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
HMPBNJCG_00632 1e-110 L Integrase core domain protein
HMPBNJCG_00633 1.1e-23 L transposase activity
HMPBNJCG_00634 8.9e-18 L transposase activity
HMPBNJCG_00635 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMPBNJCG_00636 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HMPBNJCG_00637 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMPBNJCG_00638 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HMPBNJCG_00639 1.5e-103 yjbK S Adenylate cyclase
HMPBNJCG_00640 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMPBNJCG_00641 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
HMPBNJCG_00642 2e-58 XK27_04120 S Putative amino acid metabolism
HMPBNJCG_00643 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMPBNJCG_00644 1.6e-131 puuD T peptidase C26
HMPBNJCG_00645 6.2e-120 radC E Belongs to the UPF0758 family
HMPBNJCG_00646 4.9e-272 rgpF M Rhamnan synthesis protein F
HMPBNJCG_00647 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMPBNJCG_00648 6.4e-140 rgpC GM Transport permease protein
HMPBNJCG_00649 2e-169 rgpB GT2 M Glycosyltransferase, group 2 family protein
HMPBNJCG_00650 1.1e-222 rgpA GT4 M Domain of unknown function (DUF1972)
HMPBNJCG_00651 5e-174 S Glucosyl transferase GtrII
HMPBNJCG_00652 1.8e-28 S Glucosyl transferase GtrII
HMPBNJCG_00653 1.6e-219 GT4 M transferase activity, transferring glycosyl groups
HMPBNJCG_00654 2e-217 M Psort location CytoplasmicMembrane, score
HMPBNJCG_00655 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
HMPBNJCG_00656 5.9e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
HMPBNJCG_00657 4.6e-42 S Uncharacterized conserved protein (DUF2304)
HMPBNJCG_00658 3.8e-128 arnC M group 2 family protein
HMPBNJCG_00659 1.1e-181 cpsIaJ S Glycosyltransferase like family 2
HMPBNJCG_00660 1e-184 S Glycosyltransferase like family 2
HMPBNJCG_00661 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
HMPBNJCG_00662 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMPBNJCG_00663 2.9e-235 S Predicted membrane protein (DUF2142)
HMPBNJCG_00664 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HMPBNJCG_00665 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HMPBNJCG_00666 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMPBNJCG_00667 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMPBNJCG_00668 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMPBNJCG_00669 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
HMPBNJCG_00670 2.1e-202 arcT 2.6.1.1 E Aminotransferase
HMPBNJCG_00671 9.4e-136 ET ABC transporter
HMPBNJCG_00672 1.1e-142 ET Belongs to the bacterial solute-binding protein 3 family
HMPBNJCG_00673 2.9e-84 mutT 3.6.1.55 F Nudix family
HMPBNJCG_00674 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMPBNJCG_00676 1.2e-55 V CAAX protease self-immunity
HMPBNJCG_00677 2.6e-32 S CAAX amino terminal protease family protein
HMPBNJCG_00678 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HMPBNJCG_00679 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPBNJCG_00680 2.4e-16 XK27_00735
HMPBNJCG_00681 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMPBNJCG_00683 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMPBNJCG_00686 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
HMPBNJCG_00687 6.6e-30 ycaO O OsmC-like protein
HMPBNJCG_00689 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
HMPBNJCG_00691 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
HMPBNJCG_00692 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMPBNJCG_00693 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMPBNJCG_00694 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMPBNJCG_00695 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
HMPBNJCG_00696 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMPBNJCG_00697 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMPBNJCG_00698 2.6e-109 3.1.3.18 S IA, variant 1
HMPBNJCG_00699 2.2e-117 lrgB M effector of murein hydrolase
HMPBNJCG_00700 2.2e-58 lrgA S Effector of murein hydrolase LrgA
HMPBNJCG_00702 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
HMPBNJCG_00703 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HMPBNJCG_00704 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMPBNJCG_00705 3.9e-104 wecD M Acetyltransferase GNAT family
HMPBNJCG_00706 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMPBNJCG_00707 5.1e-96 GK ROK family
HMPBNJCG_00708 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
HMPBNJCG_00709 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
HMPBNJCG_00710 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
HMPBNJCG_00711 2.3e-206 potD P spermidine putrescine ABC transporter
HMPBNJCG_00712 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
HMPBNJCG_00713 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
HMPBNJCG_00714 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMPBNJCG_00715 7.8e-171 murB 1.3.1.98 M cell wall formation
HMPBNJCG_00716 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMPBNJCG_00717 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMPBNJCG_00718 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HMPBNJCG_00719 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMPBNJCG_00720 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
HMPBNJCG_00721 0.0 ydaO E amino acid
HMPBNJCG_00722 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMPBNJCG_00723 4.1e-37 ylqC L Belongs to the UPF0109 family
HMPBNJCG_00724 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMPBNJCG_00725 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HMPBNJCG_00726 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HMPBNJCG_00727 2.1e-74 S QueT transporter
HMPBNJCG_00728 1.9e-55 L Transposase
HMPBNJCG_00729 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMPBNJCG_00730 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMPBNJCG_00731 3.7e-85 ccl S cog cog4708
HMPBNJCG_00732 7.4e-164 rbn E Belongs to the UPF0761 family
HMPBNJCG_00733 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HMPBNJCG_00734 3.3e-231 ytoI K transcriptional regulator containing CBS domains
HMPBNJCG_00735 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HMPBNJCG_00736 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMPBNJCG_00737 0.0 comEC S Competence protein ComEC
HMPBNJCG_00738 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HMPBNJCG_00739 1.3e-142 plsC 2.3.1.51 I Acyltransferase
HMPBNJCG_00740 1.7e-77 nodB3 G polysaccharide deacetylase
HMPBNJCG_00741 4.1e-22 nodB3 G polysaccharide deacetylase
HMPBNJCG_00742 2.3e-139 yabB 2.1.1.223 L Methyltransferase
HMPBNJCG_00743 1e-41 yazA L endonuclease containing a URI domain
HMPBNJCG_00744 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMPBNJCG_00745 2.3e-154 corA P CorA-like protein
HMPBNJCG_00746 1.9e-62 yjqA S Bacterial PH domain
HMPBNJCG_00747 7.8e-100 thiT S Thiamine transporter
HMPBNJCG_00748 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HMPBNJCG_00749 1.9e-201 yjbB G Permeases of the major facilitator superfamily
HMPBNJCG_00750 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMPBNJCG_00751 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
HMPBNJCG_00752 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMPBNJCG_00756 1.1e-155 cjaA ET ABC transporter substrate-binding protein
HMPBNJCG_00757 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPBNJCG_00758 3e-106 P ABC transporter (Permease
HMPBNJCG_00759 6e-115 papP P ABC transporter (Permease
HMPBNJCG_00760 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMPBNJCG_00761 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
HMPBNJCG_00762 0.0 copA 3.6.3.54 P P-type ATPase
HMPBNJCG_00763 2.7e-73 copY K Copper transport repressor, CopY TcrY family
HMPBNJCG_00764 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMPBNJCG_00765 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMPBNJCG_00766 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HMPBNJCG_00767 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HMPBNJCG_00768 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMPBNJCG_00769 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HMPBNJCG_00770 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMPBNJCG_00771 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
HMPBNJCG_00772 3.2e-56
HMPBNJCG_00773 0.0 ctpE P E1-E2 ATPase
HMPBNJCG_00774 2e-25
HMPBNJCG_00775 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMPBNJCG_00776 9.7e-28 L transposase activity
HMPBNJCG_00777 2.7e-129 K transcriptional regulator, MerR family
HMPBNJCG_00778 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
HMPBNJCG_00779 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
HMPBNJCG_00780 7.4e-64 XK27_02560 S cog cog2151
HMPBNJCG_00781 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMPBNJCG_00782 7.7e-227 ytfP S Flavoprotein
HMPBNJCG_00784 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMPBNJCG_00785 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
HMPBNJCG_00786 2.7e-183 ecsB U ABC transporter
HMPBNJCG_00787 2.3e-133 ecsA V abc transporter atp-binding protein
HMPBNJCG_00788 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HMPBNJCG_00789 5.6e-12
HMPBNJCG_00790 2.6e-55 S CD20-like family
HMPBNJCG_00791 2.1e-106
HMPBNJCG_00793 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HMPBNJCG_00794 5.8e-126 ylbM S Belongs to the UPF0348 family
HMPBNJCG_00795 2e-140 yqeM Q Methyltransferase domain protein
HMPBNJCG_00796 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMPBNJCG_00797 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HMPBNJCG_00798 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMPBNJCG_00799 3.5e-49 yhbY J RNA-binding protein
HMPBNJCG_00800 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HMPBNJCG_00801 1.8e-98 yqeG S hydrolase of the HAD superfamily
HMPBNJCG_00802 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMPBNJCG_00803 1.3e-57
HMPBNJCG_00804 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMPBNJCG_00805 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMPBNJCG_00806 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMPBNJCG_00807 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HMPBNJCG_00808 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMPBNJCG_00809 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMPBNJCG_00810 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMPBNJCG_00811 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
HMPBNJCG_00812 6.8e-101 pncA Q isochorismatase
HMPBNJCG_00813 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HMPBNJCG_00814 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HMPBNJCG_00815 2.4e-75 XK27_03180 T universal stress protein
HMPBNJCG_00818 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMPBNJCG_00819 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HMPBNJCG_00820 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HMPBNJCG_00821 0.0 yjcE P NhaP-type Na H and K H antiporters
HMPBNJCG_00823 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
HMPBNJCG_00824 1.3e-184 yhcC S radical SAM protein
HMPBNJCG_00825 2.2e-196 ylbL T Belongs to the peptidase S16 family
HMPBNJCG_00826 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMPBNJCG_00827 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
HMPBNJCG_00828 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMPBNJCG_00829 1.5e-09 S Protein of unknown function (DUF4059)
HMPBNJCG_00830 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
HMPBNJCG_00831 4.7e-163 yxeN P ABC transporter (Permease
HMPBNJCG_00832 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMPBNJCG_00834 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMPBNJCG_00835 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HMPBNJCG_00836 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
HMPBNJCG_00837 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMPBNJCG_00838 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
HMPBNJCG_00839 2.9e-87 D nuclear chromosome segregation
HMPBNJCG_00840 1.5e-127 ybbM S transport system, permease component
HMPBNJCG_00841 1.2e-117 ybbL S abc transporter atp-binding protein
HMPBNJCG_00842 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HMPBNJCG_00843 4.6e-140 cppA E CppA N-terminal
HMPBNJCG_00844 5e-44 V CAAX protease self-immunity
HMPBNJCG_00845 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HMPBNJCG_00846 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMPBNJCG_00849 3e-47 spiA K sequence-specific DNA binding
HMPBNJCG_00850 2.9e-28 blpT
HMPBNJCG_00851 6.7e-98 blpT
HMPBNJCG_00856 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
HMPBNJCG_00859 8.9e-133 agrA KT phosphorelay signal transduction system
HMPBNJCG_00860 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
HMPBNJCG_00862 7.3e-237 mesE M Transport protein ComB
HMPBNJCG_00863 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMPBNJCG_00864 0.0 mdlB V abc transporter atp-binding protein
HMPBNJCG_00865 0.0 mdlA V abc transporter atp-binding protein
HMPBNJCG_00867 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
HMPBNJCG_00868 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMPBNJCG_00869 2.3e-72 yutD J protein conserved in bacteria
HMPBNJCG_00870 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMPBNJCG_00872 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMPBNJCG_00873 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMPBNJCG_00874 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HMPBNJCG_00875 8.1e-46 ftsL D cell division protein FtsL
HMPBNJCG_00876 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMPBNJCG_00877 3e-128
HMPBNJCG_00878 9.7e-32 yhaI J Protein of unknown function (DUF805)
HMPBNJCG_00879 1.3e-08 D nuclear chromosome segregation
HMPBNJCG_00880 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMPBNJCG_00881 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMPBNJCG_00882 2.2e-285 XK27_00765
HMPBNJCG_00883 8.1e-134 ecsA_2 V abc transporter atp-binding protein
HMPBNJCG_00884 5.2e-125 S Protein of unknown function (DUF554)
HMPBNJCG_00885 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMPBNJCG_00886 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HMPBNJCG_00887 9.8e-57 liaI S membrane
HMPBNJCG_00888 7e-10 XK27_02470 K LytTr DNA-binding domain protein
HMPBNJCG_00889 1.8e-65 KT response to antibiotic
HMPBNJCG_00890 5.2e-81 yebC M Membrane
HMPBNJCG_00891 2.9e-18 yebC M Membrane
HMPBNJCG_00892 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
HMPBNJCG_00893 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HMPBNJCG_00894 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMPBNJCG_00895 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMPBNJCG_00896 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMPBNJCG_00897 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMPBNJCG_00898 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMPBNJCG_00899 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMPBNJCG_00901 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMPBNJCG_00902 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HMPBNJCG_00903 0.0 scrA 2.7.1.211 G pts system
HMPBNJCG_00904 4.1e-291 scrB 3.2.1.26 GH32 G invertase
HMPBNJCG_00905 7.5e-180 scrR K Transcriptional
HMPBNJCG_00906 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMPBNJCG_00907 3.4e-62 yqhY S protein conserved in bacteria
HMPBNJCG_00908 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMPBNJCG_00909 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
HMPBNJCG_00910 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HMPBNJCG_00912 8e-44 V 'abc transporter, ATP-binding protein
HMPBNJCG_00913 1e-58 V 'abc transporter, ATP-binding protein
HMPBNJCG_00916 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HMPBNJCG_00917 2e-169 corA P COG0598 Mg2 and Co2 transporters
HMPBNJCG_00918 3.1e-124 XK27_01040 S Pfam PF06570
HMPBNJCG_00920 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMPBNJCG_00921 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMPBNJCG_00922 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HMPBNJCG_00923 2.8e-31 XK27_05745
HMPBNJCG_00924 2.5e-230 mutY L A G-specific adenine glycosylase
HMPBNJCG_00929 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMPBNJCG_00930 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMPBNJCG_00931 1e-93 cvpA S toxin biosynthetic process
HMPBNJCG_00932 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMPBNJCG_00933 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMPBNJCG_00934 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMPBNJCG_00935 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMPBNJCG_00936 2e-47 azlD E branched-chain amino acid
HMPBNJCG_00937 1.8e-114 azlC E AzlC protein
HMPBNJCG_00938 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMPBNJCG_00939 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMPBNJCG_00940 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HMPBNJCG_00941 2.5e-33 ykzG S Belongs to the UPF0356 family
HMPBNJCG_00942 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMPBNJCG_00943 2.7e-40 pscB M CHAP domain protein
HMPBNJCG_00944 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
HMPBNJCG_00945 8.5e-63 glnR K Transcriptional regulator
HMPBNJCG_00946 1.3e-87 S Fusaric acid resistance protein-like
HMPBNJCG_00947 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMPBNJCG_00948 3.2e-42 L Transposase
HMPBNJCG_00949 1.9e-46 L transposase activity
HMPBNJCG_00950 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMPBNJCG_00951 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMPBNJCG_00952 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMPBNJCG_00953 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMPBNJCG_00954 1.1e-142 purR 2.4.2.7 F operon repressor
HMPBNJCG_00955 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
HMPBNJCG_00956 6.9e-173 rmuC S RmuC domain protein
HMPBNJCG_00957 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMPBNJCG_00958 8.6e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMPBNJCG_00959 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMPBNJCG_00961 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMPBNJCG_00962 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMPBNJCG_00963 1.6e-143 tatD L Hydrolase, tatd
HMPBNJCG_00964 7.2e-74 yccU S CoA-binding protein
HMPBNJCG_00965 4.8e-51 trxA O Belongs to the thioredoxin family
HMPBNJCG_00966 1.9e-141 S Macro domain protein
HMPBNJCG_00967 2e-09 L thioesterase
HMPBNJCG_00968 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
HMPBNJCG_00971 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMPBNJCG_00972 2.7e-62 L Transposase
HMPBNJCG_00973 1e-13 rpmH J Ribosomal protein L34
HMPBNJCG_00974 2e-186 jag S RNA-binding protein
HMPBNJCG_00975 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMPBNJCG_00976 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMPBNJCG_00977 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
HMPBNJCG_00978 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMPBNJCG_00979 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMPBNJCG_00980 6.7e-81 amiA E transmembrane transport
HMPBNJCG_00981 4.2e-74 amiA E transmembrane transport
HMPBNJCG_00982 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMPBNJCG_00983 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMPBNJCG_00984 3.5e-50 S Protein of unknown function (DUF3397)
HMPBNJCG_00985 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HMPBNJCG_00986 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
HMPBNJCG_00987 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
HMPBNJCG_00988 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMPBNJCG_00989 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HMPBNJCG_00990 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
HMPBNJCG_00991 4.3e-77 XK27_09620 S reductase
HMPBNJCG_00992 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
HMPBNJCG_00993 1.2e-131 XK27_09615 S PAS domain
HMPBNJCG_00994 1.9e-07 fnt P Formate nitrite transporter
HMPBNJCG_00995 6.4e-54 fnt P Formate nitrite transporter
HMPBNJCG_00996 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
HMPBNJCG_00997 2.8e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMPBNJCG_00998 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMPBNJCG_00999 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HMPBNJCG_01000 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMPBNJCG_01001 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMPBNJCG_01002 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMPBNJCG_01003 1.6e-21 S glycolate biosynthetic process
HMPBNJCG_01004 1.5e-64 S phosphatase activity
HMPBNJCG_01005 2e-157 rrmA 2.1.1.187 Q methyltransferase
HMPBNJCG_01008 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMPBNJCG_01009 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMPBNJCG_01010 2.4e-36 yeeD O sulfur carrier activity
HMPBNJCG_01011 1.8e-187 yeeE S Sulphur transport
HMPBNJCG_01012 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMPBNJCG_01013 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMPBNJCG_01014 4.1e-09 S Domain of unknown function (DUF4651)
HMPBNJCG_01015 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HMPBNJCG_01016 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMPBNJCG_01017 1.8e-111 S CAAX amino terminal protease family protein
HMPBNJCG_01019 5e-67 V CAAX protease self-immunity
HMPBNJCG_01020 1.4e-33 V CAAX protease self-immunity
HMPBNJCG_01021 8.8e-27 lanR K sequence-specific DNA binding
HMPBNJCG_01022 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMPBNJCG_01023 7.7e-177 ytxK 2.1.1.72 L DNA methylase
HMPBNJCG_01024 6.8e-13 comGF U Putative Competence protein ComGF
HMPBNJCG_01025 4e-72 comGF U Competence protein ComGF
HMPBNJCG_01026 1.4e-15 NU Type II secretory pathway pseudopilin
HMPBNJCG_01027 1.8e-57 cglD NU Competence protein
HMPBNJCG_01028 8.5e-43 comGC U Required for transformation and DNA binding
HMPBNJCG_01029 9.2e-153 cglB NU type II secretion system
HMPBNJCG_01030 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HMPBNJCG_01031 2.9e-68 S cog cog4699
HMPBNJCG_01032 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMPBNJCG_01033 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMPBNJCG_01034 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMPBNJCG_01035 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMPBNJCG_01036 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMPBNJCG_01037 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
HMPBNJCG_01038 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HMPBNJCG_01039 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMPBNJCG_01040 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMPBNJCG_01041 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
HMPBNJCG_01042 1.8e-57 asp S cog cog1302
HMPBNJCG_01043 3.2e-226 norN V Mate efflux family protein
HMPBNJCG_01044 1.9e-278 thrC 4.2.3.1 E Threonine synthase
HMPBNJCG_01045 1.9e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMPBNJCG_01046 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
HMPBNJCG_01047 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMPBNJCG_01048 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMPBNJCG_01049 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
HMPBNJCG_01050 0.0 pepO 3.4.24.71 O Peptidase family M13
HMPBNJCG_01051 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HMPBNJCG_01052 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HMPBNJCG_01053 1.3e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HMPBNJCG_01054 1.4e-54 treB 2.7.1.201 G PTS System
HMPBNJCG_01055 5.8e-21 treR K DNA-binding transcription factor activity
HMPBNJCG_01056 1.2e-85 treR K trehalose operon
HMPBNJCG_01057 3.3e-95 ywlG S Belongs to the UPF0340 family
HMPBNJCG_01060 2e-35 L PFAM Integrase, catalytic core
HMPBNJCG_01061 2e-94 L PFAM Integrase, catalytic core
HMPBNJCG_01062 3.3e-46 K Putative DNA-binding domain
HMPBNJCG_01063 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
HMPBNJCG_01064 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMPBNJCG_01065 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
HMPBNJCG_01070 1e-39
HMPBNJCG_01071 6.5e-31
HMPBNJCG_01072 5e-31 S Hypothetical protein (DUF2513)
HMPBNJCG_01073 7.7e-13
HMPBNJCG_01075 3.7e-216 S MvaI/BcnI restriction endonuclease family
HMPBNJCG_01077 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HMPBNJCG_01078 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
HMPBNJCG_01080 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
HMPBNJCG_01081 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
HMPBNJCG_01082 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
HMPBNJCG_01083 3.3e-09 L PFAM Integrase, catalytic core
HMPBNJCG_01084 1.8e-111 L PFAM Integrase, catalytic core
HMPBNJCG_01085 3.3e-62 rplQ J ribosomal protein l17
HMPBNJCG_01086 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMPBNJCG_01087 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMPBNJCG_01088 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMPBNJCG_01089 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMPBNJCG_01090 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMPBNJCG_01091 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMPBNJCG_01092 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMPBNJCG_01093 4.4e-58 rplO J binds to the 23S rRNA
HMPBNJCG_01094 2.5e-23 rpmD J ribosomal protein l30
HMPBNJCG_01095 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMPBNJCG_01096 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMPBNJCG_01097 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMPBNJCG_01098 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMPBNJCG_01099 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMPBNJCG_01100 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMPBNJCG_01101 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMPBNJCG_01102 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMPBNJCG_01103 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMPBNJCG_01104 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HMPBNJCG_01105 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMPBNJCG_01106 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMPBNJCG_01107 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMPBNJCG_01108 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMPBNJCG_01109 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMPBNJCG_01110 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMPBNJCG_01111 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HMPBNJCG_01112 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMPBNJCG_01113 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HMPBNJCG_01114 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMPBNJCG_01115 0.0 XK27_09800 I Acyltransferase
HMPBNJCG_01116 1.7e-35 XK27_09805 S MORN repeat protein
HMPBNJCG_01117 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMPBNJCG_01118 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMPBNJCG_01119 1.5e-89 adk 2.7.4.3 F topology modulation protein
HMPBNJCG_01120 8.6e-127 Z012_04635 K sequence-specific DNA binding
HMPBNJCG_01122 6.3e-16 C Radical SAM
HMPBNJCG_01123 3.4e-191 C Radical SAM
HMPBNJCG_01124 3.9e-287 V ABC transporter transmembrane region
HMPBNJCG_01125 2.5e-89 K sequence-specific DNA binding
HMPBNJCG_01126 1e-36 L Replication initiation factor
HMPBNJCG_01127 1.4e-107 L Replication initiation factor
HMPBNJCG_01128 1.9e-18 S Domain of unknown function (DUF3173)
HMPBNJCG_01129 3.5e-216 int L Belongs to the 'phage' integrase family
HMPBNJCG_01131 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HMPBNJCG_01132 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMPBNJCG_01133 2.8e-44 yrzL S Belongs to the UPF0297 family
HMPBNJCG_01134 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMPBNJCG_01135 4.2e-44 yrzB S Belongs to the UPF0473 family
HMPBNJCG_01136 6.6e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
HMPBNJCG_01137 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMPBNJCG_01138 7.5e-14
HMPBNJCG_01139 2.6e-91 XK27_10930 K acetyltransferase
HMPBNJCG_01140 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMPBNJCG_01141 2.3e-41 yaaA S Belongs to the UPF0246 family
HMPBNJCG_01142 1.2e-50 yaaA S Belongs to the UPF0246 family
HMPBNJCG_01143 9.9e-169 XK27_01785 S cog cog1284
HMPBNJCG_01144 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMPBNJCG_01146 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMPBNJCG_01147 5.7e-52 metE 2.1.1.14 E Methionine synthase
HMPBNJCG_01148 7.6e-64 metE 2.1.1.14 E Methionine synthase
HMPBNJCG_01149 9.2e-36 metE 2.1.1.14 E Methionine synthase
HMPBNJCG_01150 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMPBNJCG_01151 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMPBNJCG_01153 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
HMPBNJCG_01154 2.7e-95 S Hydrophobic domain protein
HMPBNJCG_01156 3.7e-27 S Membrane
HMPBNJCG_01157 3.1e-101
HMPBNJCG_01158 1.8e-23 S Small integral membrane protein
HMPBNJCG_01159 1.1e-71 M Protein conserved in bacteria
HMPBNJCG_01160 4.9e-12 K CsbD-like
HMPBNJCG_01161 3.5e-97 nudL L hydrolase
HMPBNJCG_01162 3.4e-13 nudL L hydrolase
HMPBNJCG_01163 4e-19 K negative regulation of transcription, DNA-templated
HMPBNJCG_01164 1.7e-23 K negative regulation of transcription, DNA-templated
HMPBNJCG_01166 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
HMPBNJCG_01167 1.8e-88 S Putative adhesin
HMPBNJCG_01168 3.9e-161 XK27_06930 V domain protein
HMPBNJCG_01169 6.4e-96 XK27_06935 K transcriptional regulator
HMPBNJCG_01170 4.8e-55 ypaA M Membrane
HMPBNJCG_01171 2.7e-08
HMPBNJCG_01172 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMPBNJCG_01173 8.2e-48 veg S Biofilm formation stimulator VEG
HMPBNJCG_01174 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMPBNJCG_01175 3.9e-70 rplI J binds to the 23S rRNA
HMPBNJCG_01176 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMPBNJCG_01177 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMPBNJCG_01178 1.5e-77 F NUDIX domain
HMPBNJCG_01179 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMPBNJCG_01180 0.0 S Bacterial membrane protein, YfhO
HMPBNJCG_01181 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
HMPBNJCG_01182 5.3e-85 lytE M LysM domain protein
HMPBNJCG_01183 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMPBNJCG_01184 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMPBNJCG_01185 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMPBNJCG_01186 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMPBNJCG_01187 6.3e-138 ymfM S sequence-specific DNA binding
HMPBNJCG_01188 3.1e-242 ymfH S Peptidase M16
HMPBNJCG_01189 4.8e-235 ymfF S Peptidase M16
HMPBNJCG_01190 2.4e-44 yaaA S S4 domain protein YaaA
HMPBNJCG_01191 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMPBNJCG_01192 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HMPBNJCG_01193 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HMPBNJCG_01194 4.2e-153 yvjA S membrane
HMPBNJCG_01195 6.7e-306 ybiT S abc transporter atp-binding protein
HMPBNJCG_01196 0.0 XK27_10405 S Bacterial membrane protein YfhO
HMPBNJCG_01200 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
HMPBNJCG_01201 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMPBNJCG_01202 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HMPBNJCG_01203 8.5e-134 parB K Belongs to the ParB family
HMPBNJCG_01204 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMPBNJCG_01205 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMPBNJCG_01206 1.1e-29 yyzM S Protein conserved in bacteria
HMPBNJCG_01207 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMPBNJCG_01208 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMPBNJCG_01209 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMPBNJCG_01210 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HMPBNJCG_01211 2.7e-61 divIC D Septum formation initiator
HMPBNJCG_01213 8.7e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HMPBNJCG_01214 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMPBNJCG_01215 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMPBNJCG_01216 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMPBNJCG_01217 1.3e-137 L Transposase
HMPBNJCG_01218 6.4e-33 cpsJ S Glycosyltransferase like family 2
HMPBNJCG_01219 3e-15
HMPBNJCG_01220 1.1e-71 M Glycosyltransferase sugar-binding region containing DXD motif
HMPBNJCG_01221 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
HMPBNJCG_01222 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
HMPBNJCG_01223 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
HMPBNJCG_01224 3.3e-37 L transposase activity
HMPBNJCG_01225 4e-60 L COG2801 Transposase and inactivated derivatives
HMPBNJCG_01226 2.4e-30 tra981A L Integrase core domain
HMPBNJCG_01227 8.1e-52 tnp L DDE domain
HMPBNJCG_01228 1.4e-235 cps1C S Polysaccharide biosynthesis protein
HMPBNJCG_01233 2.6e-10
HMPBNJCG_01236 1.9e-07
HMPBNJCG_01241 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMPBNJCG_01242 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HMPBNJCG_01243 5.5e-36 XK27_02060 S Transglycosylase associated protein
HMPBNJCG_01244 1.7e-54 badR K DNA-binding transcription factor activity
HMPBNJCG_01245 1e-96 S reductase
HMPBNJCG_01246 2.3e-31 L Integrase core domain protein
HMPBNJCG_01247 6.2e-36 L transposition
HMPBNJCG_01248 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
HMPBNJCG_01249 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HMPBNJCG_01252 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HMPBNJCG_01253 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMPBNJCG_01254 1.1e-83 S Putative small multi-drug export protein
HMPBNJCG_01255 6.2e-76 ctsR K Belongs to the CtsR family
HMPBNJCG_01256 0.0 clpC O Belongs to the ClpA ClpB family
HMPBNJCG_01257 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMPBNJCG_01258 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMPBNJCG_01259 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMPBNJCG_01260 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMPBNJCG_01261 6.9e-144 S SseB protein N-terminal domain
HMPBNJCG_01262 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
HMPBNJCG_01263 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMPBNJCG_01264 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMPBNJCG_01267 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMPBNJCG_01268 3.5e-91 yacP S RNA-binding protein containing a PIN domain
HMPBNJCG_01269 3.4e-155 degV S DegV family
HMPBNJCG_01270 1.8e-31 K helix-turn-helix
HMPBNJCG_01271 6.1e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMPBNJCG_01272 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMPBNJCG_01273 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HMPBNJCG_01274 1.5e-35 K sequence-specific DNA binding
HMPBNJCG_01276 0.0 S Lantibiotic dehydratase, C terminus
HMPBNJCG_01277 2.4e-231 spaC2 V Lanthionine synthetase C family protein
HMPBNJCG_01278 4.3e-183 EGP Major facilitator Superfamily
HMPBNJCG_01279 5.9e-24 3.6.4.12
HMPBNJCG_01280 5.9e-91 3.6.4.12 K Divergent AAA domain protein
HMPBNJCG_01281 7.4e-225 int L Belongs to the 'phage' integrase family
HMPBNJCG_01282 1.8e-38 S Helix-turn-helix domain
HMPBNJCG_01283 4.9e-173
HMPBNJCG_01285 3.4e-75 isp2 S pathogenesis
HMPBNJCG_01286 5.7e-91 tnp L Transposase
HMPBNJCG_01287 3.3e-225 capA M Bacterial capsule synthesis protein
HMPBNJCG_01288 3.6e-39 gcvR T UPF0237 protein
HMPBNJCG_01289 1.9e-242 XK27_08635 S UPF0210 protein
HMPBNJCG_01290 2.2e-38 ais G alpha-ribazole phosphatase activity
HMPBNJCG_01291 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HMPBNJCG_01292 1.3e-102 acmA 3.2.1.17 NU amidase activity
HMPBNJCG_01293 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMPBNJCG_01294 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMPBNJCG_01295 9.8e-298 dnaK O Heat shock 70 kDa protein
HMPBNJCG_01296 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMPBNJCG_01297 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMPBNJCG_01298 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HMPBNJCG_01299 1.7e-60 hmpT S membrane
HMPBNJCG_01302 1.2e-165 L integrase core domain
HMPBNJCG_01303 2e-52 L Transposase
HMPBNJCG_01304 1.6e-249 L Transposase
HMPBNJCG_01305 9.9e-19 S Domain of unknown function (DUF4649)
HMPBNJCG_01306 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HMPBNJCG_01307 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HMPBNJCG_01308 6.5e-87
HMPBNJCG_01309 1.6e-77 sigH K DNA-templated transcription, initiation
HMPBNJCG_01310 3.5e-149 ykuT M mechanosensitive ion channel
HMPBNJCG_01311 7.1e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMPBNJCG_01312 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMPBNJCG_01313 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMPBNJCG_01314 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
HMPBNJCG_01315 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HMPBNJCG_01316 2e-177 prmA J Ribosomal protein L11 methyltransferase
HMPBNJCG_01317 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMPBNJCG_01318 1.4e-42 F nucleotide catabolic process
HMPBNJCG_01319 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMPBNJCG_01320 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMPBNJCG_01321 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMPBNJCG_01322 1.8e-83 nrdI F Belongs to the NrdI family
HMPBNJCG_01323 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMPBNJCG_01324 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMPBNJCG_01325 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HMPBNJCG_01326 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HMPBNJCG_01327 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HMPBNJCG_01328 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HMPBNJCG_01329 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMPBNJCG_01330 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMPBNJCG_01331 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HMPBNJCG_01332 6.5e-202 yhjX P Major Facilitator
HMPBNJCG_01333 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMPBNJCG_01334 5e-94 V VanZ like family
HMPBNJCG_01335 1e-123 glnQ E abc transporter atp-binding protein
HMPBNJCG_01336 5.8e-275 glnP P ABC transporter
HMPBNJCG_01337 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMPBNJCG_01338 1.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMPBNJCG_01339 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
HMPBNJCG_01340 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HMPBNJCG_01341 1.4e-234 sufD O assembly protein SufD
HMPBNJCG_01342 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMPBNJCG_01343 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
HMPBNJCG_01344 2.2e-273 sufB O assembly protein SufB
HMPBNJCG_01345 7e-10 oppA E ABC transporter substrate-binding protein
HMPBNJCG_01346 2e-138 oppA E ABC transporter substrate-binding protein
HMPBNJCG_01347 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMPBNJCG_01348 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMPBNJCG_01349 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMPBNJCG_01350 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMPBNJCG_01351 3e-27 oppD P Belongs to the ABC transporter superfamily
HMPBNJCG_01352 2.5e-32 oppD P Belongs to the ABC transporter superfamily
HMPBNJCG_01353 1.2e-62 oppD P Belongs to the ABC transporter superfamily
HMPBNJCG_01354 3.1e-43 oppD P Belongs to the ABC transporter superfamily
HMPBNJCG_01355 7.5e-62 oppF P Belongs to the ABC transporter superfamily
HMPBNJCG_01356 4.4e-62 oppF P Belongs to the ABC transporter superfamily
HMPBNJCG_01357 6.4e-23
HMPBNJCG_01358 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMPBNJCG_01359 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMPBNJCG_01360 1.9e-223 EGP Major facilitator Superfamily
HMPBNJCG_01361 3.1e-72 adcR K transcriptional
HMPBNJCG_01362 2.2e-136 adcC P ABC transporter, ATP-binding protein
HMPBNJCG_01363 1.6e-127 adcB P ABC transporter (Permease
HMPBNJCG_01364 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HMPBNJCG_01365 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
HMPBNJCG_01366 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
HMPBNJCG_01367 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMPBNJCG_01368 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HMPBNJCG_01369 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
HMPBNJCG_01370 1.9e-127 yeeN K transcriptional regulatory protein
HMPBNJCG_01371 9.8e-50 yajC U protein transport
HMPBNJCG_01372 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMPBNJCG_01373 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
HMPBNJCG_01374 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMPBNJCG_01375 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMPBNJCG_01376 0.0 WQ51_06230 S ABC transporter substrate binding protein
HMPBNJCG_01377 5.2e-142 cmpC S abc transporter atp-binding protein
HMPBNJCG_01378 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMPBNJCG_01379 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMPBNJCG_01380 4.4e-37 L Transposase
HMPBNJCG_01381 6.4e-18 L transposase activity
HMPBNJCG_01384 4.7e-43
HMPBNJCG_01385 6.8e-56 S TM2 domain
HMPBNJCG_01386 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMPBNJCG_01387 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMPBNJCG_01388 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
HMPBNJCG_01389 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HMPBNJCG_01390 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HMPBNJCG_01391 6e-55 cof Q phosphatase activity
HMPBNJCG_01392 6.2e-35 cof Q phosphatase activity
HMPBNJCG_01393 1.6e-137 glcR K transcriptional regulator (DeoR family)
HMPBNJCG_01394 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMPBNJCG_01395 3.8e-40 K transcriptional
HMPBNJCG_01397 2.6e-76 S thiolester hydrolase activity
HMPBNJCG_01398 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
HMPBNJCG_01399 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMPBNJCG_01400 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMPBNJCG_01401 1.9e-77 yhaI L Membrane
HMPBNJCG_01402 5.1e-259 pepC 3.4.22.40 E aminopeptidase
HMPBNJCG_01403 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMPBNJCG_01404 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMPBNJCG_01405 3.1e-95 ypsA S Belongs to the UPF0398 family
HMPBNJCG_01406 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMPBNJCG_01407 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMPBNJCG_01408 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HMPBNJCG_01409 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HMPBNJCG_01410 2.5e-23
HMPBNJCG_01411 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMPBNJCG_01412 7.3e-80 XK27_09675 K -acetyltransferase
HMPBNJCG_01413 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMPBNJCG_01414 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMPBNJCG_01415 5.2e-59 L Integrase core domain protein
HMPBNJCG_01416 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMPBNJCG_01417 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMPBNJCG_01418 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMPBNJCG_01419 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HMPBNJCG_01420 8.8e-98 ybhL S Belongs to the BI1 family
HMPBNJCG_01423 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMPBNJCG_01424 3.7e-91 K transcriptional regulator
HMPBNJCG_01425 7.6e-36 yneF S UPF0154 protein
HMPBNJCG_01426 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMPBNJCG_01427 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMPBNJCG_01428 3.5e-99 XK27_09740 S Phosphoesterase
HMPBNJCG_01429 7.8e-85 ykuL S CBS domain
HMPBNJCG_01430 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HMPBNJCG_01431 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMPBNJCG_01432 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMPBNJCG_01433 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMPBNJCG_01434 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HMPBNJCG_01435 1.2e-258 trkH P Cation transport protein
HMPBNJCG_01436 1.5e-247 trkA P Potassium transporter peripheral membrane component
HMPBNJCG_01437 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMPBNJCG_01438 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMPBNJCG_01439 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HMPBNJCG_01440 5.6e-161 K sequence-specific DNA binding
HMPBNJCG_01441 1.2e-32 V protein secretion by the type I secretion system
HMPBNJCG_01442 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMPBNJCG_01443 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMPBNJCG_01444 1.6e-25 V protein secretion by the type I secretion system
HMPBNJCG_01445 1.8e-27 comA V protein secretion by the type I secretion system
HMPBNJCG_01446 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMPBNJCG_01447 3.7e-51 yhaI L Membrane
HMPBNJCG_01448 6.7e-36 S Domain of unknown function (DUF4173)
HMPBNJCG_01449 9.2e-132 S Domain of unknown function (DUF4173)
HMPBNJCG_01450 6.8e-95 ureI S AmiS/UreI family transporter
HMPBNJCG_01451 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HMPBNJCG_01452 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HMPBNJCG_01453 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HMPBNJCG_01454 6.6e-78 ureE O enzyme active site formation
HMPBNJCG_01455 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HMPBNJCG_01456 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HMPBNJCG_01457 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HMPBNJCG_01458 2.7e-177 cbiM P PDGLE domain
HMPBNJCG_01459 1.1e-136 P cobalt transport protein
HMPBNJCG_01460 1.6e-131 cbiO P ABC transporter
HMPBNJCG_01461 5.3e-153 ET amino acid transport
HMPBNJCG_01462 4.1e-78 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMPBNJCG_01463 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMPBNJCG_01464 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
HMPBNJCG_01465 3.8e-205 EGP Transmembrane secretion effector
HMPBNJCG_01466 1.8e-153 ET amino acid transport
HMPBNJCG_01467 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
HMPBNJCG_01468 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HMPBNJCG_01469 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HMPBNJCG_01470 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HMPBNJCG_01471 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMPBNJCG_01472 5.2e-98 metI P ABC transporter (Permease
HMPBNJCG_01473 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HMPBNJCG_01474 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HMPBNJCG_01475 8e-94 S UPF0397 protein
HMPBNJCG_01476 0.0 ykoD P abc transporter atp-binding protein
HMPBNJCG_01477 1.2e-146 cbiQ P cobalt transport
HMPBNJCG_01478 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMPBNJCG_01479 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
HMPBNJCG_01480 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
HMPBNJCG_01481 1.2e-244 P COG0168 Trk-type K transport systems, membrane components
HMPBNJCG_01482 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HMPBNJCG_01483 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
HMPBNJCG_01484 3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPBNJCG_01485 2.8e-282 T PhoQ Sensor
HMPBNJCG_01486 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMPBNJCG_01487 6.5e-218 dnaB L Replication initiation and membrane attachment
HMPBNJCG_01488 4.4e-166 dnaI L Primosomal protein DnaI
HMPBNJCG_01489 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMPBNJCG_01491 1.2e-34
HMPBNJCG_01492 3e-27 L Integrase core domain protein
HMPBNJCG_01493 3.4e-50 L transposition
HMPBNJCG_01494 5.7e-23 L Transposase
HMPBNJCG_01495 7.8e-28 L transposase activity
HMPBNJCG_01496 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMPBNJCG_01497 4.2e-62 manO S protein conserved in bacteria
HMPBNJCG_01498 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
HMPBNJCG_01499 2.3e-116 manM G pts system
HMPBNJCG_01500 1.1e-181 manL 2.7.1.191 G pts system
HMPBNJCG_01501 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HMPBNJCG_01502 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HMPBNJCG_01503 1.9e-248 pbuO S permease
HMPBNJCG_01504 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HMPBNJCG_01505 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
HMPBNJCG_01506 2.5e-220 brpA K Transcriptional
HMPBNJCG_01507 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HMPBNJCG_01508 3.1e-212 nusA K Participates in both transcription termination and antitermination
HMPBNJCG_01509 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HMPBNJCG_01510 1.4e-41 ylxQ J ribosomal protein
HMPBNJCG_01511 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMPBNJCG_01512 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMPBNJCG_01513 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
HMPBNJCG_01514 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
HMPBNJCG_01515 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HMPBNJCG_01516 6.2e-85 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HMPBNJCG_01517 3.2e-49 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HMPBNJCG_01518 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMPBNJCG_01519 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HMPBNJCG_01520 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HMPBNJCG_01521 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
HMPBNJCG_01522 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HMPBNJCG_01525 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMPBNJCG_01526 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMPBNJCG_01527 1.2e-74 ylbF S Belongs to the UPF0342 family
HMPBNJCG_01528 7.1e-46 ylbG S UPF0298 protein
HMPBNJCG_01529 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HMPBNJCG_01530 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HMPBNJCG_01531 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
HMPBNJCG_01532 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HMPBNJCG_01533 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HMPBNJCG_01534 6.8e-69 acuB S IMP dehydrogenase activity
HMPBNJCG_01535 8.9e-41 acuB S IMP dehydrogenase activity
HMPBNJCG_01536 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMPBNJCG_01537 1.1e-110 yvyE 3.4.13.9 S YigZ family
HMPBNJCG_01538 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HMPBNJCG_01539 1.7e-122 comFC S Competence protein
HMPBNJCG_01540 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMPBNJCG_01547 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMPBNJCG_01548 6.4e-108 S Domain of unknown function (DUF1803)
HMPBNJCG_01549 7.8e-102 ygaC J Belongs to the UPF0374 family
HMPBNJCG_01550 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMPBNJCG_01551 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMPBNJCG_01552 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
HMPBNJCG_01553 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMPBNJCG_01554 6.8e-75 S Haloacid dehalogenase-like hydrolase
HMPBNJCG_01555 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HMPBNJCG_01556 4e-72 marR K Transcriptional regulator, MarR family
HMPBNJCG_01557 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMPBNJCG_01558 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMPBNJCG_01559 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HMPBNJCG_01560 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMPBNJCG_01561 1.6e-126 IQ reductase
HMPBNJCG_01562 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMPBNJCG_01563 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMPBNJCG_01564 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMPBNJCG_01565 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HMPBNJCG_01566 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMPBNJCG_01567 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HMPBNJCG_01568 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMPBNJCG_01569 1.1e-65 tnp L Transposase
HMPBNJCG_01570 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HMPBNJCG_01571 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
HMPBNJCG_01572 4.7e-27 L Transposase and inactivated derivatives, TnpA family
HMPBNJCG_01573 3.4e-126 tnp L Transposase
HMPBNJCG_01575 8e-277 S Protein of unknown function (DUF3114)
HMPBNJCG_01576 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
HMPBNJCG_01577 7.7e-198 V (ABC) transporter
HMPBNJCG_01578 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
HMPBNJCG_01579 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
HMPBNJCG_01580 1.1e-113 K sequence-specific DNA binding
HMPBNJCG_01581 8.4e-155 L COG2801 Transposase and inactivated derivatives
HMPBNJCG_01582 6.6e-38 L transposase activity
HMPBNJCG_01583 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
HMPBNJCG_01584 1.8e-84 L Transposase
HMPBNJCG_01585 5.5e-122 fruR K transcriptional
HMPBNJCG_01586 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMPBNJCG_01587 0.0 fruA 2.7.1.202 G phosphotransferase system
HMPBNJCG_01588 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMPBNJCG_01589 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMPBNJCG_01591 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HMPBNJCG_01592 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMPBNJCG_01593 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMPBNJCG_01594 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HMPBNJCG_01595 6.4e-29 2.3.1.128 K acetyltransferase
HMPBNJCG_01596 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMPBNJCG_01597 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMPBNJCG_01598 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMPBNJCG_01599 2.6e-64 WQ51_03320 S cog cog4835
HMPBNJCG_01600 9.8e-91 XK27_08360 S EDD domain protein, DegV family
HMPBNJCG_01601 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMPBNJCG_01602 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMPBNJCG_01603 0.0 yfmR S abc transporter atp-binding protein
HMPBNJCG_01604 1.6e-24 U response to pH
HMPBNJCG_01605 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HMPBNJCG_01606 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HMPBNJCG_01607 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMPBNJCG_01608 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMPBNJCG_01609 9.4e-77 K DNA-binding transcription factor activity
HMPBNJCG_01610 0.0 lmrA1 V abc transporter atp-binding protein
HMPBNJCG_01611 0.0 lmrA2 V abc transporter atp-binding protein
HMPBNJCG_01612 5.4e-45 K Acetyltransferase (GNAT) family
HMPBNJCG_01613 3.2e-78 sptS 2.7.13.3 T Histidine kinase
HMPBNJCG_01614 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMPBNJCG_01615 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMPBNJCG_01616 5.3e-161 cvfB S Protein conserved in bacteria
HMPBNJCG_01617 7.4e-35 yozE S Belongs to the UPF0346 family
HMPBNJCG_01618 6.7e-124 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
HMPBNJCG_01619 2.3e-61 rlpA M LysM domain protein
HMPBNJCG_01620 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
HMPBNJCG_01624 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMPBNJCG_01625 1.8e-164 K transcriptional regulator (lysR family)
HMPBNJCG_01626 1.4e-186 coiA 3.6.4.12 S Competence protein
HMPBNJCG_01627 0.0 pepF E oligoendopeptidase F
HMPBNJCG_01628 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
HMPBNJCG_01629 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HMPBNJCG_01630 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMPBNJCG_01631 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HMPBNJCG_01632 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HMPBNJCG_01633 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
HMPBNJCG_01634 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMPBNJCG_01635 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HMPBNJCG_01636 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMPBNJCG_01637 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMPBNJCG_01638 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HMPBNJCG_01639 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HMPBNJCG_01640 2.2e-130 yxkH G deacetylase
HMPBNJCG_01641 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HMPBNJCG_01642 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMPBNJCG_01643 5.5e-153 rarD S Transporter
HMPBNJCG_01644 2.2e-15 T peptidase
HMPBNJCG_01645 8.9e-14 coiA 3.6.4.12 S Competence protein
HMPBNJCG_01646 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HMPBNJCG_01647 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMPBNJCG_01648 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMPBNJCG_01649 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMPBNJCG_01650 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HMPBNJCG_01651 3.3e-78 atpF C ATP synthase F(0) sector subunit b
HMPBNJCG_01652 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMPBNJCG_01653 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMPBNJCG_01654 7.4e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMPBNJCG_01655 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMPBNJCG_01656 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMPBNJCG_01657 2.8e-230 ftsW D Belongs to the SEDS family
HMPBNJCG_01658 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMPBNJCG_01659 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMPBNJCG_01660 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMPBNJCG_01661 1.9e-161 holB 2.7.7.7 L dna polymerase iii
HMPBNJCG_01662 2.1e-135 yaaT S stage 0 sporulation protein
HMPBNJCG_01663 1.1e-34 yabA L Involved in initiation control of chromosome replication
HMPBNJCG_01664 3.9e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMPBNJCG_01665 7.5e-233 amt P Ammonium Transporter
HMPBNJCG_01666 1.1e-53 glnB K Belongs to the P(II) protein family
HMPBNJCG_01667 4.9e-106 mur1 NU mannosyl-glycoprotein
HMPBNJCG_01668 1.7e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HMPBNJCG_01669 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
HMPBNJCG_01670 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMPBNJCG_01671 1.8e-53
HMPBNJCG_01672 7.5e-26
HMPBNJCG_01673 1.5e-59
HMPBNJCG_01674 6.1e-63 S membrane
HMPBNJCG_01675 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMPBNJCG_01676 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMPBNJCG_01677 4.5e-39 ynzC S UPF0291 protein
HMPBNJCG_01678 1.8e-254 cycA E permease
HMPBNJCG_01679 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
HMPBNJCG_01680 2.8e-24 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HMPBNJCG_01681 5.8e-71 pts33BCA G pts system
HMPBNJCG_01682 9e-96 pts33BCA G pts system
HMPBNJCG_01683 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
HMPBNJCG_01684 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMPBNJCG_01689 1.4e-167 fhuR K transcriptional regulator (lysR family)
HMPBNJCG_01690 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMPBNJCG_01691 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMPBNJCG_01692 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMPBNJCG_01693 4.9e-227 pyrP F uracil Permease
HMPBNJCG_01694 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMPBNJCG_01695 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HMPBNJCG_01696 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HMPBNJCG_01697 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
HMPBNJCG_01698 4e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMPBNJCG_01699 1.6e-33 V permease protein
HMPBNJCG_01700 1e-09 V permease protein
HMPBNJCG_01701 8.8e-21 V permease protein
HMPBNJCG_01702 1.7e-07 V efflux transmembrane transporter activity
HMPBNJCG_01703 1.1e-24 ytrF V efflux transmembrane transporter activity
HMPBNJCG_01704 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMPBNJCG_01705 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMPBNJCG_01707 0.0 mdlB V abc transporter atp-binding protein
HMPBNJCG_01708 0.0 lmrA V abc transporter atp-binding protein
HMPBNJCG_01709 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMPBNJCG_01710 5.8e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMPBNJCG_01711 6.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HMPBNJCG_01712 2.5e-132 rr02 KT response regulator
HMPBNJCG_01713 3.5e-202 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HMPBNJCG_01714 4.8e-168 V ABC transporter
HMPBNJCG_01715 5.4e-122 sagI S ABC-2 type transporter
HMPBNJCG_01716 4.5e-196 yceA S Belongs to the UPF0176 family
HMPBNJCG_01717 8e-28 XK27_00085 K Transcriptional
HMPBNJCG_01718 1.7e-23
HMPBNJCG_01719 1.2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
HMPBNJCG_01720 2.8e-112 S VIT family
HMPBNJCG_01721 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMPBNJCG_01722 2.4e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HMPBNJCG_01723 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
HMPBNJCG_01724 2e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HMPBNJCG_01725 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMPBNJCG_01726 8.8e-104 GBS0088 J protein conserved in bacteria
HMPBNJCG_01727 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HMPBNJCG_01728 1.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMPBNJCG_01729 1.6e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
HMPBNJCG_01730 7.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMPBNJCG_01731 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMPBNJCG_01732 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HMPBNJCG_01733 2.5e-21
HMPBNJCG_01734 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMPBNJCG_01736 3.5e-07 U protein secretion
HMPBNJCG_01737 2.5e-51 U protein secretion
HMPBNJCG_01738 7.4e-08 M Pilin isopeptide linkage domain protein
HMPBNJCG_01739 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HMPBNJCG_01740 1.5e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HMPBNJCG_01741 3.5e-49 XK27_13030
HMPBNJCG_01742 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMPBNJCG_01743 8.3e-55 S hydrolase activity, acting on ester bonds
HMPBNJCG_01744 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMPBNJCG_01745 6.8e-164 S Protein of unknown function (DUF3114)
HMPBNJCG_01746 1.2e-22 S Protein of unknown function (DUF3114)
HMPBNJCG_01747 1.5e-118 yqfA K protein, Hemolysin III
HMPBNJCG_01748 1e-25 K hmm pf08876
HMPBNJCG_01749 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMPBNJCG_01750 1.7e-218 mvaS 2.3.3.10 I synthase
HMPBNJCG_01751 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMPBNJCG_01752 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMPBNJCG_01753 9.7e-22
HMPBNJCG_01754 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMPBNJCG_01755 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HMPBNJCG_01756 1.5e-250 mmuP E amino acid
HMPBNJCG_01757 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HMPBNJCG_01758 1.4e-29 S Domain of unknown function (DUF1912)
HMPBNJCG_01759 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
HMPBNJCG_01760 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMPBNJCG_01761 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMPBNJCG_01762 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMPBNJCG_01763 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HMPBNJCG_01764 4.8e-16 S Protein of unknown function (DUF2969)
HMPBNJCG_01767 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
HMPBNJCG_01770 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
HMPBNJCG_01771 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
HMPBNJCG_01772 3.7e-70 M Pfam SNARE associated Golgi protein
HMPBNJCG_01773 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
HMPBNJCG_01774 1.6e-08 S oxidoreductase
HMPBNJCG_01775 9.3e-59 S oxidoreductase
HMPBNJCG_01776 9.7e-66 S oxidoreductase
HMPBNJCG_01777 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
HMPBNJCG_01778 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HMPBNJCG_01779 0.0 clpE O Belongs to the ClpA ClpB family
HMPBNJCG_01780 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMPBNJCG_01781 1.3e-34 ykuJ S protein conserved in bacteria
HMPBNJCG_01782 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HMPBNJCG_01783 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPBNJCG_01784 3.1e-78 feoA P FeoA domain protein
HMPBNJCG_01785 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HMPBNJCG_01786 1.5e-07
HMPBNJCG_01787 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMPBNJCG_01788 2.2e-45 K sequence-specific DNA binding
HMPBNJCG_01789 1.5e-35 yugF I carboxylic ester hydrolase activity
HMPBNJCG_01790 7.5e-23 I Alpha/beta hydrolase family
HMPBNJCG_01791 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMPBNJCG_01792 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMPBNJCG_01793 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HMPBNJCG_01794 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMPBNJCG_01795 5.8e-64 licT K transcriptional antiterminator
HMPBNJCG_01796 6.8e-53 licT K transcriptional antiterminator
HMPBNJCG_01797 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMPBNJCG_01798 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMPBNJCG_01799 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMPBNJCG_01800 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMPBNJCG_01801 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMPBNJCG_01802 2.5e-220 mdtG EGP Major facilitator Superfamily
HMPBNJCG_01803 2e-33 secG U Preprotein translocase subunit SecG
HMPBNJCG_01804 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMPBNJCG_01805 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMPBNJCG_01806 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMPBNJCG_01807 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HMPBNJCG_01808 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HMPBNJCG_01809 4.4e-183 ccpA K Catabolite control protein A
HMPBNJCG_01810 2.8e-28 yyaQ S YjbR
HMPBNJCG_01811 6.6e-101 yyaQ V Protein conserved in bacteria
HMPBNJCG_01812 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMPBNJCG_01813 1e-78 yueI S Protein of unknown function (DUF1694)
HMPBNJCG_01814 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMPBNJCG_01815 2e-25 WQ51_00785
HMPBNJCG_01816 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMPBNJCG_01817 2e-219 ywbD 2.1.1.191 J Methyltransferase
HMPBNJCG_01818 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMPBNJCG_01819 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMPBNJCG_01820 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMPBNJCG_01821 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMPBNJCG_01822 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HMPBNJCG_01823 3.2e-53 yheA S Belongs to the UPF0342 family
HMPBNJCG_01824 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMPBNJCG_01825 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMPBNJCG_01826 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMPBNJCG_01827 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
HMPBNJCG_01828 6.4e-252 msrR K Transcriptional regulator
HMPBNJCG_01829 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
HMPBNJCG_01830 2.4e-203 I acyl-CoA dehydrogenase
HMPBNJCG_01831 4.5e-97 mip S hydroperoxide reductase activity
HMPBNJCG_01832 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMPBNJCG_01833 8.9e-20
HMPBNJCG_01834 3.2e-46
HMPBNJCG_01835 1e-31 K Cro/C1-type HTH DNA-binding domain
HMPBNJCG_01836 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HMPBNJCG_01837 9.7e-34 estA E GDSL-like Lipase/Acylhydrolase
HMPBNJCG_01838 1.1e-94
HMPBNJCG_01839 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMPBNJCG_01840 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMPBNJCG_01841 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMPBNJCG_01842 2.6e-194 S CRISPR-associated protein Csn2 subfamily St
HMPBNJCG_01843 2.7e-146 ycgQ S TIGR03943 family
HMPBNJCG_01844 4.6e-155 XK27_03015 S permease
HMPBNJCG_01846 0.0 yhgF K Transcriptional accessory protein
HMPBNJCG_01847 9.9e-42 pspC KT PspC domain
HMPBNJCG_01848 2e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMPBNJCG_01849 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMPBNJCG_01851 5.5e-69 ytxH S General stress protein
HMPBNJCG_01853 2e-177 yegQ O Peptidase U32
HMPBNJCG_01854 3.4e-252 yegQ O Peptidase U32
HMPBNJCG_01855 8.1e-46 S CHY zinc finger
HMPBNJCG_01856 8.4e-88 bioY S biotin synthase
HMPBNJCG_01858 1.1e-33 XK27_12190 S protein conserved in bacteria
HMPBNJCG_01859 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
HMPBNJCG_01860 4.8e-11
HMPBNJCG_01861 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HMPBNJCG_01862 4.1e-225 mutH L DNA mismatch repair enzyme MutH
HMPBNJCG_01863 5.2e-29 S SIR2-like domain
HMPBNJCG_01864 1.2e-33 S SIR2-like domain
HMPBNJCG_01865 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMPBNJCG_01866 6.4e-158 M LysM domain
HMPBNJCG_01867 7.6e-16
HMPBNJCG_01868 2.3e-175 S hydrolase
HMPBNJCG_01869 1.9e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HMPBNJCG_01870 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMPBNJCG_01871 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HMPBNJCG_01872 2.7e-27 P Hemerythrin HHE cation binding domain protein
HMPBNJCG_01873 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMPBNJCG_01874 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
HMPBNJCG_01875 3.9e-290 hsdM 2.1.1.72 V N-6 DNA Methylase
HMPBNJCG_01876 2.2e-147 3.1.21.3 V type I restriction modification DNA specificity domain
HMPBNJCG_01878 2.5e-44
HMPBNJCG_01879 3e-38
HMPBNJCG_01880 2.3e-171 spd F DNA RNA non-specific endonuclease
HMPBNJCG_01881 1.5e-92 lemA S LemA family
HMPBNJCG_01882 1.8e-135 htpX O Belongs to the peptidase M48B family
HMPBNJCG_01883 4.2e-75 S Psort location CytoplasmicMembrane, score
HMPBNJCG_01884 6.2e-56 S Domain of unknown function (DUF4430)
HMPBNJCG_01885 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMPBNJCG_01886 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
HMPBNJCG_01887 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HMPBNJCG_01888 5.4e-161 L Transposase
HMPBNJCG_01889 3e-50 L Transposase
HMPBNJCG_01890 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HMPBNJCG_01891 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HMPBNJCG_01892 3.5e-91 dps P Belongs to the Dps family
HMPBNJCG_01893 1.1e-80 perR P Belongs to the Fur family
HMPBNJCG_01894 8.4e-28 yqgQ S protein conserved in bacteria
HMPBNJCG_01895 2.2e-179 glk 2.7.1.2 G Glucokinase
HMPBNJCG_01896 0.0 typA T GTP-binding protein TypA
HMPBNJCG_01898 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMPBNJCG_01899 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMPBNJCG_01900 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMPBNJCG_01901 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMPBNJCG_01902 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMPBNJCG_01903 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMPBNJCG_01904 6.8e-96 sepF D cell septum assembly
HMPBNJCG_01905 2.6e-34 yggT D integral membrane protein
HMPBNJCG_01906 4.2e-144 ylmH T S4 RNA-binding domain
HMPBNJCG_01907 1.8e-135 divIVA D Cell division protein DivIVA
HMPBNJCG_01908 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMPBNJCG_01909 5.5e-30
HMPBNJCG_01910 8.4e-10
HMPBNJCG_01911 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
HMPBNJCG_01912 2e-45 rpmE2 J 50S ribosomal protein L31
HMPBNJCG_01913 8.3e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMPBNJCG_01914 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HMPBNJCG_01915 8.9e-155 gst O Glutathione S-transferase
HMPBNJCG_01916 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMPBNJCG_01917 4.5e-111 tdk 2.7.1.21 F thymidine kinase
HMPBNJCG_01918 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMPBNJCG_01919 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMPBNJCG_01920 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMPBNJCG_01921 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMPBNJCG_01922 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
HMPBNJCG_01923 8e-100 pvaA M lytic transglycosylase activity
HMPBNJCG_01924 0.0 yfiB1 V abc transporter atp-binding protein
HMPBNJCG_01925 0.0 XK27_10035 V abc transporter atp-binding protein
HMPBNJCG_01926 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
HMPBNJCG_01927 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMPBNJCG_01928 3.9e-237 dltB M Membrane protein involved in D-alanine export
HMPBNJCG_01929 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMPBNJCG_01930 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)