ORF_ID e_value Gene_name EC_number CAZy COGs Description
KLGGCMCB_00011 5.3e-11
KLGGCMCB_00017 5.5e-139 mreC M Involved in formation and maintenance of cell shape
KLGGCMCB_00018 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KLGGCMCB_00019 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
KLGGCMCB_00020 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLGGCMCB_00021 2.9e-218 araT 2.6.1.1 E Aminotransferase
KLGGCMCB_00022 2.6e-143 recO L Involved in DNA repair and RecF pathway recombination
KLGGCMCB_00023 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KLGGCMCB_00024 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLGGCMCB_00025 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KLGGCMCB_00026 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLGGCMCB_00027 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KLGGCMCB_00028 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KLGGCMCB_00029 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KLGGCMCB_00030 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KLGGCMCB_00031 6.1e-79 L transposase activity
KLGGCMCB_00032 1.3e-49 L transposition
KLGGCMCB_00033 6.3e-34 L Integrase core domain protein
KLGGCMCB_00034 2.3e-161 S CHAP domain
KLGGCMCB_00035 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
KLGGCMCB_00036 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KLGGCMCB_00037 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLGGCMCB_00038 9.2e-141 1.1.1.169 H Ketopantoate reductase
KLGGCMCB_00039 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KLGGCMCB_00040 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KLGGCMCB_00041 1.2e-09 L Transposase
KLGGCMCB_00042 7.8e-211 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KLGGCMCB_00043 8.3e-221 nodC 2.4.1.212 GT2 M Chitin synthase
KLGGCMCB_00044 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KLGGCMCB_00045 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KLGGCMCB_00046 3.5e-91 dps P Belongs to the Dps family
KLGGCMCB_00047 1.1e-80 perR P Belongs to the Fur family
KLGGCMCB_00048 8.4e-28 yqgQ S protein conserved in bacteria
KLGGCMCB_00049 2.2e-179 glk 2.7.1.2 G Glucokinase
KLGGCMCB_00050 0.0 typA T GTP-binding protein TypA
KLGGCMCB_00052 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KLGGCMCB_00053 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLGGCMCB_00054 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KLGGCMCB_00055 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KLGGCMCB_00056 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KLGGCMCB_00057 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KLGGCMCB_00058 6.8e-96 sepF D cell septum assembly
KLGGCMCB_00059 2.6e-34 yggT D integral membrane protein
KLGGCMCB_00060 4.2e-144 ylmH T S4 RNA-binding domain
KLGGCMCB_00061 1.8e-135 divIVA D Cell division protein DivIVA
KLGGCMCB_00062 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLGGCMCB_00063 5.5e-30
KLGGCMCB_00064 8.4e-10
KLGGCMCB_00065 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
KLGGCMCB_00066 2e-45 rpmE2 J 50S ribosomal protein L31
KLGGCMCB_00067 8.3e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KLGGCMCB_00068 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KLGGCMCB_00069 8.9e-155 gst O Glutathione S-transferase
KLGGCMCB_00070 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KLGGCMCB_00071 4.5e-111 tdk 2.7.1.21 F thymidine kinase
KLGGCMCB_00072 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLGGCMCB_00073 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KLGGCMCB_00074 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KLGGCMCB_00075 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLGGCMCB_00076 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KLGGCMCB_00077 8e-100 pvaA M lytic transglycosylase activity
KLGGCMCB_00078 0.0 yfiB1 V abc transporter atp-binding protein
KLGGCMCB_00079 0.0 XK27_10035 V abc transporter atp-binding protein
KLGGCMCB_00080 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
KLGGCMCB_00081 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLGGCMCB_00082 3.9e-237 dltB M Membrane protein involved in D-alanine export
KLGGCMCB_00083 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLGGCMCB_00084 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KLGGCMCB_00085 6.5e-54 L transposition
KLGGCMCB_00086 7.7e-19 L transposase activity
KLGGCMCB_00087 2.5e-40 L Transposase
KLGGCMCB_00088 0.0 3.6.3.8 P cation transport ATPase
KLGGCMCB_00089 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KLGGCMCB_00090 1.9e-105 V Abi-like protein
KLGGCMCB_00092 2.3e-12
KLGGCMCB_00094 2e-296 S DNA primase
KLGGCMCB_00095 3e-164 KL Phage plasmid primase P4 family
KLGGCMCB_00096 2.4e-22
KLGGCMCB_00097 1.2e-14
KLGGCMCB_00101 1.8e-19 K Cro/C1-type HTH DNA-binding domain
KLGGCMCB_00102 1e-21 xre K transcriptional
KLGGCMCB_00103 6.9e-220 sip L Belongs to the 'phage' integrase family
KLGGCMCB_00105 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KLGGCMCB_00106 7.3e-166 metF 1.5.1.20 E reductase
KLGGCMCB_00107 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KLGGCMCB_00108 1.7e-94 panT S ECF transporter, substrate-specific component
KLGGCMCB_00109 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLGGCMCB_00110 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KLGGCMCB_00111 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KLGGCMCB_00112 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLGGCMCB_00113 2.8e-40 T PhoQ Sensor
KLGGCMCB_00114 1.7e-43 T PhoQ Sensor
KLGGCMCB_00115 5.8e-79 T PhoQ Sensor
KLGGCMCB_00116 2.1e-30 rpsT J rRNA binding
KLGGCMCB_00117 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
KLGGCMCB_00118 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
KLGGCMCB_00119 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KLGGCMCB_00120 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KLGGCMCB_00121 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLGGCMCB_00122 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLGGCMCB_00123 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KLGGCMCB_00124 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KLGGCMCB_00125 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KLGGCMCB_00126 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
KLGGCMCB_00127 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KLGGCMCB_00128 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KLGGCMCB_00129 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KLGGCMCB_00130 3.1e-81 ypmB S Protein conserved in bacteria
KLGGCMCB_00131 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KLGGCMCB_00132 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KLGGCMCB_00133 1.5e-07
KLGGCMCB_00134 2.4e-30
KLGGCMCB_00135 3e-13
KLGGCMCB_00136 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KLGGCMCB_00137 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KLGGCMCB_00138 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KLGGCMCB_00139 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KLGGCMCB_00140 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KLGGCMCB_00141 4.2e-18 D nuclear chromosome segregation
KLGGCMCB_00142 1.5e-135 yejC S cyclic nucleotide-binding protein
KLGGCMCB_00143 1.2e-163 rapZ S Displays ATPase and GTPase activities
KLGGCMCB_00144 1.8e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KLGGCMCB_00145 8.7e-162 whiA K May be required for sporulation
KLGGCMCB_00146 8e-90 pepD E Dipeptidase
KLGGCMCB_00147 5.8e-41 pepD E dipeptidase activity
KLGGCMCB_00148 5.4e-32 cspD K Cold shock protein domain
KLGGCMCB_00149 9.4e-43 K Cold-Shock Protein
KLGGCMCB_00150 2.8e-221 L Transposase
KLGGCMCB_00151 0.0 copB 3.6.3.4 P P-type ATPase
KLGGCMCB_00152 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLGGCMCB_00153 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KLGGCMCB_00154 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
KLGGCMCB_00155 4.8e-157 glcU U Glucose uptake
KLGGCMCB_00156 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
KLGGCMCB_00157 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
KLGGCMCB_00158 2.2e-101 XK27_10720 D peptidase activity
KLGGCMCB_00159 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
KLGGCMCB_00160 1.7e-08
KLGGCMCB_00162 1.2e-172 yeiH S Membrane
KLGGCMCB_00163 5.5e-119 mur1 NU muramidase
KLGGCMCB_00164 1.9e-83 L transposition
KLGGCMCB_00165 2.6e-166 cpsY K Transcriptional regulator
KLGGCMCB_00166 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KLGGCMCB_00167 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
KLGGCMCB_00168 2e-104 artQ P ABC transporter (Permease
KLGGCMCB_00169 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
KLGGCMCB_00170 1.1e-158 aatB ET ABC transporter substrate-binding protein
KLGGCMCB_00171 3.5e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLGGCMCB_00172 2.5e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLGGCMCB_00173 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
KLGGCMCB_00174 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
KLGGCMCB_00175 9.3e-20 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KLGGCMCB_00176 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KLGGCMCB_00177 4.5e-126 gntR1 K transcriptional
KLGGCMCB_00178 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KLGGCMCB_00179 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLGGCMCB_00180 4.1e-87 niaX
KLGGCMCB_00181 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
KLGGCMCB_00182 6.9e-127 K DNA-binding helix-turn-helix protein
KLGGCMCB_00183 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KLGGCMCB_00184 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLGGCMCB_00185 4.1e-167 GK ROK family
KLGGCMCB_00186 8.3e-159 dprA LU DNA protecting protein DprA
KLGGCMCB_00187 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLGGCMCB_00188 1.4e-150 S TraX protein
KLGGCMCB_00189 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLGGCMCB_00190 2.4e-251 T PhoQ Sensor
KLGGCMCB_00191 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KLGGCMCB_00192 1.1e-152 XK27_05470 E Methionine synthase
KLGGCMCB_00193 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KLGGCMCB_00194 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLGGCMCB_00195 1.8e-51 IQ Acetoin reductase
KLGGCMCB_00196 3.9e-19 IQ Acetoin reductase
KLGGCMCB_00197 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KLGGCMCB_00198 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KLGGCMCB_00201 1.3e-212 pqqE C radical SAM domain protein
KLGGCMCB_00202 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KLGGCMCB_00203 6.6e-61 EGP Major facilitator Superfamily
KLGGCMCB_00204 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KLGGCMCB_00205 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KLGGCMCB_00206 6.4e-104 V ABC transporter (Permease
KLGGCMCB_00207 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KLGGCMCB_00208 1.6e-10
KLGGCMCB_00209 1.2e-97 K Transcriptional regulator, TetR family
KLGGCMCB_00210 1.2e-158 czcD P cation diffusion facilitator family transporter
KLGGCMCB_00211 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KLGGCMCB_00212 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KLGGCMCB_00213 6e-08 S Hydrolases of the alpha beta superfamily
KLGGCMCB_00214 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
KLGGCMCB_00215 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
KLGGCMCB_00218 2.6e-143 2.4.2.3 F Phosphorylase superfamily
KLGGCMCB_00219 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KLGGCMCB_00220 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
KLGGCMCB_00221 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
KLGGCMCB_00222 6.6e-73 dinF V Mate efflux family protein
KLGGCMCB_00223 4.8e-41 dinF V Mate efflux family protein
KLGGCMCB_00225 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KLGGCMCB_00226 3.7e-190
KLGGCMCB_00227 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
KLGGCMCB_00228 3.5e-28 3.4.13.21 I Protein conserved in bacteria
KLGGCMCB_00230 5.7e-118 S TraX protein
KLGGCMCB_00231 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KLGGCMCB_00232 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KLGGCMCB_00233 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KLGGCMCB_00234 4.7e-143 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLGGCMCB_00235 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLGGCMCB_00236 6.8e-133 cas6 S Pfam:DUF2276
KLGGCMCB_00237 0.0 csm1 S CRISPR-associated protein Csm1 family
KLGGCMCB_00238 5.6e-62 csm2 L Pfam:DUF310
KLGGCMCB_00239 1.1e-116 csm3 L RAMP superfamily
KLGGCMCB_00240 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
KLGGCMCB_00241 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
KLGGCMCB_00242 2.1e-14 csm6 S Psort location Cytoplasmic, score
KLGGCMCB_00243 5.2e-74 csm6 S Psort location Cytoplasmic, score
KLGGCMCB_00244 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KLGGCMCB_00245 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLGGCMCB_00246 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
KLGGCMCB_00248 2.5e-267 dtpT E transporter
KLGGCMCB_00249 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
KLGGCMCB_00250 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
KLGGCMCB_00251 1.8e-67 yecS P ABC transporter (Permease
KLGGCMCB_00253 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KLGGCMCB_00254 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
KLGGCMCB_00255 5.4e-104 yfiF3 K sequence-specific DNA binding
KLGGCMCB_00256 4.3e-147 L Transposase
KLGGCMCB_00257 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KLGGCMCB_00258 1.8e-240 agcS E (Alanine) symporter
KLGGCMCB_00259 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KLGGCMCB_00260 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
KLGGCMCB_00261 1.8e-59 Q phosphatase activity
KLGGCMCB_00262 9.3e-62 S haloacid dehalogenase-like hydrolase
KLGGCMCB_00263 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KLGGCMCB_00264 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KLGGCMCB_00265 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
KLGGCMCB_00266 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
KLGGCMCB_00267 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLGGCMCB_00268 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KLGGCMCB_00269 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KLGGCMCB_00270 1.9e-43 yktA S Belongs to the UPF0223 family
KLGGCMCB_00271 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KLGGCMCB_00272 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KLGGCMCB_00273 3.3e-158 pstS P phosphate
KLGGCMCB_00274 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
KLGGCMCB_00275 2e-155 pstA P phosphate transport system permease
KLGGCMCB_00276 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLGGCMCB_00277 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLGGCMCB_00278 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
KLGGCMCB_00279 0.0 pepN 3.4.11.2 E aminopeptidase
KLGGCMCB_00280 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KLGGCMCB_00281 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
KLGGCMCB_00282 1.1e-17
KLGGCMCB_00283 3.7e-09
KLGGCMCB_00284 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KLGGCMCB_00285 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KLGGCMCB_00286 2.3e-23 L Transposase
KLGGCMCB_00287 4.6e-25 tatA U protein secretion
KLGGCMCB_00288 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KLGGCMCB_00289 1.1e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KLGGCMCB_00290 5.6e-233 ycdB P peroxidase
KLGGCMCB_00291 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
KLGGCMCB_00292 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00293 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00294 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00295 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00296 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00297 1.9e-37 3.5.1.28 NU amidase activity
KLGGCMCB_00298 8.5e-266 3.5.1.28 NU amidase activity
KLGGCMCB_00299 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KLGGCMCB_00300 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KLGGCMCB_00301 0.0 lpdA 1.8.1.4 C Dehydrogenase
KLGGCMCB_00302 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KLGGCMCB_00303 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KLGGCMCB_00304 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KLGGCMCB_00305 5e-38 P membrane protein (DUF2207)
KLGGCMCB_00306 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
KLGGCMCB_00307 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KLGGCMCB_00308 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLGGCMCB_00309 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLGGCMCB_00310 1.2e-157 rssA S Phospholipase, patatin family
KLGGCMCB_00311 3.9e-78 estA E GDSL-like protein
KLGGCMCB_00312 2.6e-15 estA E Lysophospholipase L1 and related esterases
KLGGCMCB_00313 3.7e-293 S unusual protein kinase
KLGGCMCB_00314 4.9e-39 S granule-associated protein
KLGGCMCB_00315 7.9e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KLGGCMCB_00316 5.8e-28 bglH 3.2.1.86 GT1 G beta-glucosidase activity
KLGGCMCB_00317 1.3e-199 S hmm pf01594
KLGGCMCB_00318 1.6e-44 G alpha-ribazole phosphatase activity
KLGGCMCB_00319 2e-33 G Belongs to the phosphoglycerate mutase family
KLGGCMCB_00320 1.1e-25 G Belongs to the phosphoglycerate mutase family
KLGGCMCB_00321 8.8e-66 pgm G Belongs to the phosphoglycerate mutase family
KLGGCMCB_00322 1.7e-80 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KLGGCMCB_00323 4.9e-94 V VanZ like family
KLGGCMCB_00326 1.3e-57 T Toxic component of a toxin-antitoxin (TA) module
KLGGCMCB_00328 8.2e-70 argR K Regulates arginine biosynthesis genes
KLGGCMCB_00329 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KLGGCMCB_00330 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLGGCMCB_00331 7e-34 S Protein of unknown function (DUF3021)
KLGGCMCB_00332 1.2e-61 KT phosphorelay signal transduction system
KLGGCMCB_00334 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLGGCMCB_00336 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KLGGCMCB_00337 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KLGGCMCB_00338 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
KLGGCMCB_00339 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLGGCMCB_00340 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KLGGCMCB_00341 6.4e-33 cpsJ S Glycosyltransferase like family 2
KLGGCMCB_00342 3e-15
KLGGCMCB_00343 1.1e-71 M Glycosyltransferase sugar-binding region containing DXD motif
KLGGCMCB_00344 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
KLGGCMCB_00345 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
KLGGCMCB_00346 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
KLGGCMCB_00347 3.3e-37 L transposase activity
KLGGCMCB_00348 4e-60 L COG2801 Transposase and inactivated derivatives
KLGGCMCB_00349 2.4e-30 tra981A L Integrase core domain
KLGGCMCB_00350 8.1e-52 tnp L DDE domain
KLGGCMCB_00351 1.4e-235 cps1C S Polysaccharide biosynthesis protein
KLGGCMCB_00352 9.1e-110 L Transposase
KLGGCMCB_00353 2.4e-93 L Transposase
KLGGCMCB_00354 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
KLGGCMCB_00355 3e-139 L Integrase core domain
KLGGCMCB_00356 2.2e-22 L Transposase
KLGGCMCB_00357 1.7e-27 tnp L DDE domain
KLGGCMCB_00358 8.5e-23 rgpAc GT4 M group 1 family protein
KLGGCMCB_00359 5.7e-250 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KLGGCMCB_00360 5.3e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
KLGGCMCB_00361 2.6e-105 cps4C M biosynthesis protein
KLGGCMCB_00362 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KLGGCMCB_00363 3.8e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KLGGCMCB_00364 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KLGGCMCB_00365 1.7e-48 yfeJ 6.3.5.2 F glutamine amidotransferase
KLGGCMCB_00366 2.5e-43 yfeJ 6.3.5.2 F glutamine amidotransferase
KLGGCMCB_00367 3.6e-40 clcA_2 P chloride
KLGGCMCB_00368 3.8e-42 clcA_2 P chloride channel
KLGGCMCB_00369 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KLGGCMCB_00370 9.3e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KLGGCMCB_00371 6.6e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KLGGCMCB_00373 4e-21 V Glucan-binding protein C
KLGGCMCB_00374 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
KLGGCMCB_00375 2.4e-275 pepV 3.5.1.18 E Dipeptidase
KLGGCMCB_00376 3.2e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KLGGCMCB_00377 6.9e-86 XK27_03610 K Gnat family
KLGGCMCB_00378 9.1e-10 L COG1943 Transposase and inactivated derivatives
KLGGCMCB_00379 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KLGGCMCB_00380 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KLGGCMCB_00381 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KLGGCMCB_00382 2.8e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KLGGCMCB_00383 3.9e-15 M LysM domain
KLGGCMCB_00384 2.9e-90 ebsA S Family of unknown function (DUF5322)
KLGGCMCB_00385 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KLGGCMCB_00386 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KLGGCMCB_00387 4.9e-224 G COG0457 FOG TPR repeat
KLGGCMCB_00388 1.1e-175 yubA S permease
KLGGCMCB_00389 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KLGGCMCB_00390 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KLGGCMCB_00391 2.5e-124 ftsE D cell division ATP-binding protein FtsE
KLGGCMCB_00392 1.8e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KLGGCMCB_00393 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KLGGCMCB_00394 4.3e-180 yjjH S Calcineurin-like phosphoesterase
KLGGCMCB_00395 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KLGGCMCB_00396 0.0 pacL 3.6.3.8 P cation transport ATPase
KLGGCMCB_00397 2.6e-67 ywiB S Domain of unknown function (DUF1934)
KLGGCMCB_00398 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
KLGGCMCB_00399 9.2e-147 yidA S hydrolases of the HAD superfamily
KLGGCMCB_00400 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KLGGCMCB_00401 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KLGGCMCB_00402 1.5e-247 vicK 2.7.13.3 T Histidine kinase
KLGGCMCB_00403 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLGGCMCB_00404 1e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
KLGGCMCB_00405 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KLGGCMCB_00406 8e-115 gltJ P ABC transporter (Permease
KLGGCMCB_00407 4.2e-110 tcyB_2 P ABC transporter (permease)
KLGGCMCB_00408 1.4e-124 endA F DNA RNA non-specific endonuclease
KLGGCMCB_00409 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
KLGGCMCB_00410 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLGGCMCB_00412 3.7e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLGGCMCB_00413 4.9e-21 G Domain of unknown function (DUF4832)
KLGGCMCB_00414 8.4e-53 G Domain of unknown function (DUF4832)
KLGGCMCB_00415 1.5e-211 cotH M CotH kinase protein
KLGGCMCB_00416 6.8e-185 pelG M Putative exopolysaccharide Exporter (EPS-E)
KLGGCMCB_00417 1.9e-109 pelF GT4 M Domain of unknown function (DUF3492)
KLGGCMCB_00418 7.6e-160 pelF GT4 M Domain of unknown function (DUF3492)
KLGGCMCB_00419 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KLGGCMCB_00420 4.1e-143
KLGGCMCB_00421 7.6e-134 5.1.3.2 GM Psort location CytoplasmicMembrane, score
KLGGCMCB_00422 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLGGCMCB_00423 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KLGGCMCB_00424 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLGGCMCB_00425 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KLGGCMCB_00426 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLGGCMCB_00427 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
KLGGCMCB_00429 7.7e-35
KLGGCMCB_00432 7.8e-202 S Phage integrase family
KLGGCMCB_00434 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KLGGCMCB_00435 4.3e-133 XK27_05110 P chloride
KLGGCMCB_00436 1.2e-61 XK27_05110 P chloride
KLGGCMCB_00437 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KLGGCMCB_00438 1.3e-282 clcA P Chloride transporter, ClC family
KLGGCMCB_00439 6.7e-75 fld C Flavodoxin
KLGGCMCB_00441 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
KLGGCMCB_00442 3.5e-151 estA CE1 S Putative esterase
KLGGCMCB_00443 1e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLGGCMCB_00444 1.2e-135 XK27_08845 S abc transporter atp-binding protein
KLGGCMCB_00445 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KLGGCMCB_00446 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
KLGGCMCB_00447 3.2e-17 S Domain of unknown function (DUF4649)
KLGGCMCB_00449 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
KLGGCMCB_00450 1.1e-22 Q the current gene model (or a revised gene model) may contain a frame shift
KLGGCMCB_00451 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
KLGGCMCB_00452 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KLGGCMCB_00453 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KLGGCMCB_00454 0.0 dnaE 2.7.7.7 L DNA polymerase
KLGGCMCB_00455 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
KLGGCMCB_00456 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KLGGCMCB_00457 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KLGGCMCB_00458 2.5e-43 ysdA L Membrane
KLGGCMCB_00459 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KLGGCMCB_00460 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KLGGCMCB_00461 3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLGGCMCB_00462 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KLGGCMCB_00464 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLGGCMCB_00465 1.7e-83 ypmS S Protein conserved in bacteria
KLGGCMCB_00466 6e-144 ypmR E lipolytic protein G-D-S-L family
KLGGCMCB_00467 1e-148 DegV S DegV family
KLGGCMCB_00468 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
KLGGCMCB_00469 1.8e-72 argR K Regulates arginine biosynthesis genes
KLGGCMCB_00470 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KLGGCMCB_00471 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLGGCMCB_00472 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
KLGGCMCB_00473 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLGGCMCB_00476 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLGGCMCB_00477 2.9e-125 dnaD
KLGGCMCB_00478 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KLGGCMCB_00479 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLGGCMCB_00480 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KLGGCMCB_00481 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KLGGCMCB_00482 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KLGGCMCB_00483 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KLGGCMCB_00484 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KLGGCMCB_00485 1.6e-239 rodA D Belongs to the SEDS family
KLGGCMCB_00486 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
KLGGCMCB_00487 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KLGGCMCB_00488 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KLGGCMCB_00489 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KLGGCMCB_00490 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KLGGCMCB_00491 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KLGGCMCB_00492 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KLGGCMCB_00493 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KLGGCMCB_00494 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KLGGCMCB_00495 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KLGGCMCB_00497 4.2e-86 L Integrase core domain protein
KLGGCMCB_00498 1.1e-53 L transposition
KLGGCMCB_00499 1.8e-21 L Transposase
KLGGCMCB_00500 5.2e-36 L transposase activity
KLGGCMCB_00501 1.3e-22 XK27_08085
KLGGCMCB_00502 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KLGGCMCB_00503 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KLGGCMCB_00504 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KLGGCMCB_00505 1.1e-121 ylfI S tigr01906
KLGGCMCB_00506 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KLGGCMCB_00507 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
KLGGCMCB_00508 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KLGGCMCB_00511 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLGGCMCB_00512 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KLGGCMCB_00513 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KLGGCMCB_00514 1.1e-206 yurR 1.4.5.1 E oxidoreductase
KLGGCMCB_00515 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
KLGGCMCB_00516 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLGGCMCB_00517 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KLGGCMCB_00518 1.7e-70 gtrA S GtrA-like protein
KLGGCMCB_00519 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLGGCMCB_00520 6e-169 ybbR S Protein conserved in bacteria
KLGGCMCB_00521 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KLGGCMCB_00522 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KLGGCMCB_00523 8.7e-150 cobQ S glutamine amidotransferase
KLGGCMCB_00524 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLGGCMCB_00525 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
KLGGCMCB_00526 0.0 uup S abc transporter atp-binding protein
KLGGCMCB_00527 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KLGGCMCB_00528 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
KLGGCMCB_00529 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KLGGCMCB_00530 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KLGGCMCB_00531 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLGGCMCB_00532 7.9e-39 ptsH G phosphocarrier protein Hpr
KLGGCMCB_00533 3.3e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
KLGGCMCB_00534 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
KLGGCMCB_00535 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KLGGCMCB_00536 2.2e-34 nrdH O Glutaredoxin
KLGGCMCB_00537 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLGGCMCB_00538 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLGGCMCB_00540 4.2e-71 L Transposase (IS116 IS110 IS902 family)
KLGGCMCB_00541 3.3e-26 L Transposase (IS116 IS110 IS902 family)
KLGGCMCB_00542 1.2e-164 ypuA S secreted protein
KLGGCMCB_00543 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
KLGGCMCB_00544 5.1e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KLGGCMCB_00545 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLGGCMCB_00546 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLGGCMCB_00547 3.4e-258 noxE P NADH oxidase
KLGGCMCB_00548 1.9e-294 yfmM S abc transporter atp-binding protein
KLGGCMCB_00549 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
KLGGCMCB_00550 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KLGGCMCB_00551 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KLGGCMCB_00552 2e-86 S ECF-type riboflavin transporter, S component
KLGGCMCB_00554 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KLGGCMCB_00555 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KLGGCMCB_00558 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLGGCMCB_00559 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLGGCMCB_00560 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLGGCMCB_00561 0.0 smc D Required for chromosome condensation and partitioning
KLGGCMCB_00562 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KLGGCMCB_00563 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KLGGCMCB_00564 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLGGCMCB_00565 2.4e-92 pat 2.3.1.183 M acetyltransferase
KLGGCMCB_00570 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
KLGGCMCB_00573 8.9e-133 agrA KT phosphorelay signal transduction system
KLGGCMCB_00574 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
KLGGCMCB_00576 7.3e-237 mesE M Transport protein ComB
KLGGCMCB_00577 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLGGCMCB_00578 0.0 mdlB V abc transporter atp-binding protein
KLGGCMCB_00579 0.0 mdlA V abc transporter atp-binding protein
KLGGCMCB_00581 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KLGGCMCB_00582 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KLGGCMCB_00583 2.3e-72 yutD J protein conserved in bacteria
KLGGCMCB_00584 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KLGGCMCB_00586 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KLGGCMCB_00587 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLGGCMCB_00588 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KLGGCMCB_00589 8.1e-46 ftsL D cell division protein FtsL
KLGGCMCB_00590 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KLGGCMCB_00591 3e-128
KLGGCMCB_00592 9.7e-32 yhaI J Protein of unknown function (DUF805)
KLGGCMCB_00593 1.3e-08 D nuclear chromosome segregation
KLGGCMCB_00594 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLGGCMCB_00595 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLGGCMCB_00596 2.2e-285 XK27_00765
KLGGCMCB_00597 8.1e-134 ecsA_2 V abc transporter atp-binding protein
KLGGCMCB_00598 5.2e-125 S Protein of unknown function (DUF554)
KLGGCMCB_00599 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KLGGCMCB_00600 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KLGGCMCB_00601 9.8e-57 liaI S membrane
KLGGCMCB_00602 7e-10 XK27_02470 K LytTr DNA-binding domain protein
KLGGCMCB_00603 1.8e-65 KT response to antibiotic
KLGGCMCB_00604 5.2e-81 yebC M Membrane
KLGGCMCB_00605 2.9e-18 yebC M Membrane
KLGGCMCB_00606 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KLGGCMCB_00607 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KLGGCMCB_00608 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KLGGCMCB_00609 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLGGCMCB_00610 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KLGGCMCB_00611 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLGGCMCB_00612 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLGGCMCB_00613 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KLGGCMCB_00615 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KLGGCMCB_00616 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KLGGCMCB_00617 0.0 scrA 2.7.1.211 G pts system
KLGGCMCB_00618 4.1e-291 scrB 3.2.1.26 GH32 G invertase
KLGGCMCB_00619 7.5e-180 scrR K Transcriptional
KLGGCMCB_00620 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLGGCMCB_00621 3.4e-62 yqhY S protein conserved in bacteria
KLGGCMCB_00622 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLGGCMCB_00623 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
KLGGCMCB_00624 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KLGGCMCB_00626 8e-44 V 'abc transporter, ATP-binding protein
KLGGCMCB_00627 1e-58 V 'abc transporter, ATP-binding protein
KLGGCMCB_00630 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KLGGCMCB_00631 2e-169 corA P COG0598 Mg2 and Co2 transporters
KLGGCMCB_00632 3.1e-124 XK27_01040 S Pfam PF06570
KLGGCMCB_00634 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KLGGCMCB_00635 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLGGCMCB_00636 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KLGGCMCB_00637 2.8e-31 XK27_05745
KLGGCMCB_00638 2.5e-230 mutY L A G-specific adenine glycosylase
KLGGCMCB_00643 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLGGCMCB_00644 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KLGGCMCB_00645 1e-93 cvpA S toxin biosynthetic process
KLGGCMCB_00646 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KLGGCMCB_00647 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLGGCMCB_00648 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KLGGCMCB_00649 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KLGGCMCB_00650 2e-47 azlD E branched-chain amino acid
KLGGCMCB_00651 1.8e-114 azlC E AzlC protein
KLGGCMCB_00652 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLGGCMCB_00653 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KLGGCMCB_00654 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KLGGCMCB_00655 2.5e-33 ykzG S Belongs to the UPF0356 family
KLGGCMCB_00656 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLGGCMCB_00657 2.7e-40 pscB M CHAP domain protein
KLGGCMCB_00658 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
KLGGCMCB_00659 8.5e-63 glnR K Transcriptional regulator
KLGGCMCB_00660 1.3e-87 S Fusaric acid resistance protein-like
KLGGCMCB_00661 1.1e-12
KLGGCMCB_00662 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLGGCMCB_00663 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KLGGCMCB_00664 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KLGGCMCB_00665 1.2e-62 bioY S biotin transmembrane transporter activity
KLGGCMCB_00666 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
KLGGCMCB_00667 1.5e-138 proV E abc transporter atp-binding protein
KLGGCMCB_00668 4.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
KLGGCMCB_00669 3e-111 proWZ P ABC transporter (Permease
KLGGCMCB_00670 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
KLGGCMCB_00671 1.6e-205 S Protein of unknown function (DUF917)
KLGGCMCB_00672 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KLGGCMCB_00673 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
KLGGCMCB_00674 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLGGCMCB_00675 1.5e-192 desK 2.7.13.3 T Histidine kinase
KLGGCMCB_00676 1.4e-133 yvfS V ABC-2 type transporter
KLGGCMCB_00677 8.7e-159 XK27_09825 V abc transporter atp-binding protein
KLGGCMCB_00680 8.1e-163 yocS S Transporter
KLGGCMCB_00681 1.2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KLGGCMCB_00682 7.5e-115 yvfS V Transporter
KLGGCMCB_00683 3.9e-151 XK27_09825 V abc transporter atp-binding protein
KLGGCMCB_00684 2.7e-14 liaI KT membrane
KLGGCMCB_00685 2.6e-30 liaI KT membrane
KLGGCMCB_00686 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
KLGGCMCB_00687 0.0 V ABC transporter (permease)
KLGGCMCB_00688 1.9e-133 macB2 V ABC transporter, ATP-binding protein
KLGGCMCB_00689 3.1e-165 T Histidine kinase
KLGGCMCB_00690 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLGGCMCB_00691 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KLGGCMCB_00692 3.3e-69 pbuX F xanthine permease
KLGGCMCB_00693 9.2e-119 pbuX F xanthine permease
KLGGCMCB_00694 1.5e-247 norM V Multidrug efflux pump
KLGGCMCB_00695 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLGGCMCB_00696 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
KLGGCMCB_00697 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
KLGGCMCB_00698 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
KLGGCMCB_00699 4.8e-25 csbD K CsbD-like
KLGGCMCB_00700 6.2e-228 yfnA E amino acid
KLGGCMCB_00701 5.1e-110 XK27_02070 S nitroreductase
KLGGCMCB_00702 9.5e-150 1.13.11.2 S glyoxalase
KLGGCMCB_00703 5.6e-77 ywnA K Transcriptional regulator
KLGGCMCB_00704 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
KLGGCMCB_00705 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLGGCMCB_00706 1.4e-110 drgA C Nitroreductase
KLGGCMCB_00707 3e-102 yoaK S Protein of unknown function (DUF1275)
KLGGCMCB_00709 6.8e-161 yvgN C reductase
KLGGCMCB_00710 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLGGCMCB_00711 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
KLGGCMCB_00713 1.1e-37 BP1961 P nitric oxide dioxygenase activity
KLGGCMCB_00714 1.4e-54 K response regulator
KLGGCMCB_00715 9.3e-72 S Signal peptide protein, YSIRK family
KLGGCMCB_00717 4.5e-61
KLGGCMCB_00718 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLGGCMCB_00719 1e-137
KLGGCMCB_00720 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
KLGGCMCB_00721 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
KLGGCMCB_00722 5.8e-109 MA20_06410 E LysE type translocator
KLGGCMCB_00723 5.6e-08
KLGGCMCB_00724 2.7e-09
KLGGCMCB_00725 0.0 M family 8
KLGGCMCB_00727 1.5e-162 hrtB V MacB-like periplasmic core domain
KLGGCMCB_00728 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
KLGGCMCB_00729 1.1e-151 V MatE
KLGGCMCB_00731 3.9e-110 C Fe-S oxidoreductases
KLGGCMCB_00732 1.2e-176 EGP Major Facilitator Superfamily
KLGGCMCB_00733 5.5e-258 I radical SAM domain protein
KLGGCMCB_00735 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KLGGCMCB_00736 1.4e-150 L Integrase core domain protein
KLGGCMCB_00737 1.8e-87 L transposase activity
KLGGCMCB_00739 2.8e-85
KLGGCMCB_00740 0.0 sbcC L ATPase involved in DNA repair
KLGGCMCB_00741 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KLGGCMCB_00742 0.0 lacL 3.2.1.23 G -beta-galactosidase
KLGGCMCB_00743 0.0 lacS G transporter
KLGGCMCB_00744 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KLGGCMCB_00745 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLGGCMCB_00746 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KLGGCMCB_00747 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KLGGCMCB_00748 2.3e-184 galR K Transcriptional regulator
KLGGCMCB_00749 2.7e-08 L Integrase core domain protein
KLGGCMCB_00750 1.2e-25 L transposition
KLGGCMCB_00751 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KLGGCMCB_00752 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KLGGCMCB_00753 2.5e-101 V abc transporter atp-binding protein
KLGGCMCB_00754 4.3e-40 V abc transporter atp-binding protein
KLGGCMCB_00755 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KLGGCMCB_00756 6.4e-62 L Transposase
KLGGCMCB_00757 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00758 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00759 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00760 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KLGGCMCB_00761 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KLGGCMCB_00762 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KLGGCMCB_00763 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLGGCMCB_00766 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLGGCMCB_00767 5.8e-175 vraS 2.7.13.3 T Histidine kinase
KLGGCMCB_00768 3.7e-120 yvqF KT membrane
KLGGCMCB_00769 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KLGGCMCB_00770 2e-132 stp 3.1.3.16 T phosphatase
KLGGCMCB_00771 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLGGCMCB_00772 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLGGCMCB_00773 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLGGCMCB_00774 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KLGGCMCB_00775 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KLGGCMCB_00776 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KLGGCMCB_00777 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
KLGGCMCB_00778 2.1e-148 supH S overlaps another CDS with the same product name
KLGGCMCB_00779 8.6e-63 yvoA_1 K Transcriptional
KLGGCMCB_00780 2.8e-120 skfE V abc transporter atp-binding protein
KLGGCMCB_00781 3.3e-133 V ATPase activity
KLGGCMCB_00782 4.3e-172 oppF P Belongs to the ABC transporter superfamily
KLGGCMCB_00783 2.2e-204 oppD P Belongs to the ABC transporter superfamily
KLGGCMCB_00784 4.9e-168 amiD P ABC transporter (Permease
KLGGCMCB_00785 4.2e-278 amiC P ABC transporter (Permease
KLGGCMCB_00786 3.7e-140 amiA E ABC transporter, substrate-binding protein, family 5
KLGGCMCB_00787 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KLGGCMCB_00788 8.1e-45 L Transposase
KLGGCMCB_00789 4.1e-158 L COG2801 Transposase and inactivated derivatives
KLGGCMCB_00790 1.2e-24 oppF P Belongs to the ABC transporter superfamily
KLGGCMCB_00791 3.8e-45 oppF P Belongs to the ABC transporter superfamily
KLGGCMCB_00792 1.4e-40 tatD L Hydrolase, tatd
KLGGCMCB_00793 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
KLGGCMCB_00794 1e-110 L Integrase core domain protein
KLGGCMCB_00795 1.1e-23 L transposase activity
KLGGCMCB_00796 8.9e-18 L transposase activity
KLGGCMCB_00797 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KLGGCMCB_00798 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KLGGCMCB_00799 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLGGCMCB_00800 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KLGGCMCB_00801 1.5e-103 yjbK S Adenylate cyclase
KLGGCMCB_00802 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLGGCMCB_00803 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
KLGGCMCB_00804 2e-58 XK27_04120 S Putative amino acid metabolism
KLGGCMCB_00805 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KLGGCMCB_00806 1.6e-131 puuD T peptidase C26
KLGGCMCB_00807 6.2e-120 radC E Belongs to the UPF0758 family
KLGGCMCB_00808 4.9e-272 rgpF M Rhamnan synthesis protein F
KLGGCMCB_00809 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KLGGCMCB_00810 6.4e-140 rgpC GM Transport permease protein
KLGGCMCB_00811 2e-169 rgpB GT2 M Glycosyltransferase, group 2 family protein
KLGGCMCB_00812 1.1e-222 rgpA GT4 M Domain of unknown function (DUF1972)
KLGGCMCB_00813 5e-174 S Glucosyl transferase GtrII
KLGGCMCB_00814 1.8e-28 S Glucosyl transferase GtrII
KLGGCMCB_00815 1.6e-219 GT4 M transferase activity, transferring glycosyl groups
KLGGCMCB_00816 2e-217 M Psort location CytoplasmicMembrane, score
KLGGCMCB_00817 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
KLGGCMCB_00818 5.9e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
KLGGCMCB_00819 4.6e-42 S Uncharacterized conserved protein (DUF2304)
KLGGCMCB_00820 1.3e-128 arnC M group 2 family protein
KLGGCMCB_00821 1.1e-181 cpsIaJ S Glycosyltransferase like family 2
KLGGCMCB_00822 1e-184 S Glycosyltransferase like family 2
KLGGCMCB_00823 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
KLGGCMCB_00824 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLGGCMCB_00825 2.9e-235 S Predicted membrane protein (DUF2142)
KLGGCMCB_00826 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KLGGCMCB_00827 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KLGGCMCB_00828 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KLGGCMCB_00829 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KLGGCMCB_00830 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KLGGCMCB_00831 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
KLGGCMCB_00832 2.1e-202 arcT 2.6.1.1 E Aminotransferase
KLGGCMCB_00833 9.4e-136 ET ABC transporter
KLGGCMCB_00834 1.1e-142 ET Belongs to the bacterial solute-binding protein 3 family
KLGGCMCB_00835 2.9e-84 mutT 3.6.1.55 F Nudix family
KLGGCMCB_00836 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KLGGCMCB_00838 1.2e-55 V CAAX protease self-immunity
KLGGCMCB_00839 2.6e-32 S CAAX amino terminal protease family protein
KLGGCMCB_00840 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KLGGCMCB_00841 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KLGGCMCB_00842 2.4e-16 XK27_00735
KLGGCMCB_00843 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLGGCMCB_00845 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLGGCMCB_00848 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
KLGGCMCB_00849 6.6e-30 ycaO O OsmC-like protein
KLGGCMCB_00851 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
KLGGCMCB_00853 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
KLGGCMCB_00854 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLGGCMCB_00855 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLGGCMCB_00856 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KLGGCMCB_00857 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
KLGGCMCB_00858 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KLGGCMCB_00859 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLGGCMCB_00860 2.6e-109 3.1.3.18 S IA, variant 1
KLGGCMCB_00861 2.2e-117 lrgB M effector of murein hydrolase
KLGGCMCB_00862 2.2e-58 lrgA S Effector of murein hydrolase LrgA
KLGGCMCB_00864 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
KLGGCMCB_00865 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KLGGCMCB_00866 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLGGCMCB_00867 3.9e-104 wecD M Acetyltransferase GNAT family
KLGGCMCB_00868 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KLGGCMCB_00869 5.1e-96 GK ROK family
KLGGCMCB_00870 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
KLGGCMCB_00871 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
KLGGCMCB_00872 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
KLGGCMCB_00873 2.3e-206 potD P spermidine putrescine ABC transporter
KLGGCMCB_00874 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
KLGGCMCB_00875 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
KLGGCMCB_00876 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KLGGCMCB_00877 7.8e-171 murB 1.3.1.98 M cell wall formation
KLGGCMCB_00878 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KLGGCMCB_00879 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KLGGCMCB_00880 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KLGGCMCB_00881 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KLGGCMCB_00882 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
KLGGCMCB_00883 0.0 ydaO E amino acid
KLGGCMCB_00884 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLGGCMCB_00885 4.1e-37 ylqC L Belongs to the UPF0109 family
KLGGCMCB_00886 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KLGGCMCB_00887 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KLGGCMCB_00888 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
KLGGCMCB_00889 2.1e-74 S QueT transporter
KLGGCMCB_00890 1.9e-55 L Transposase
KLGGCMCB_00891 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KLGGCMCB_00892 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLGGCMCB_00893 3.7e-85 ccl S cog cog4708
KLGGCMCB_00894 7.4e-164 rbn E Belongs to the UPF0761 family
KLGGCMCB_00895 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KLGGCMCB_00896 3.3e-231 ytoI K transcriptional regulator containing CBS domains
KLGGCMCB_00897 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KLGGCMCB_00898 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLGGCMCB_00899 0.0 comEC S Competence protein ComEC
KLGGCMCB_00900 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KLGGCMCB_00901 1.3e-142 plsC 2.3.1.51 I Acyltransferase
KLGGCMCB_00902 1.7e-77 nodB3 G polysaccharide deacetylase
KLGGCMCB_00903 4.1e-22 nodB3 G polysaccharide deacetylase
KLGGCMCB_00904 2.3e-139 yabB 2.1.1.223 L Methyltransferase
KLGGCMCB_00905 1e-41 yazA L endonuclease containing a URI domain
KLGGCMCB_00906 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KLGGCMCB_00907 2.3e-154 corA P CorA-like protein
KLGGCMCB_00908 1.9e-62 yjqA S Bacterial PH domain
KLGGCMCB_00909 7.8e-100 thiT S Thiamine transporter
KLGGCMCB_00910 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KLGGCMCB_00911 1.9e-201 yjbB G Permeases of the major facilitator superfamily
KLGGCMCB_00912 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KLGGCMCB_00913 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
KLGGCMCB_00914 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KLGGCMCB_00918 1.1e-155 cjaA ET ABC transporter substrate-binding protein
KLGGCMCB_00919 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
KLGGCMCB_00920 3e-106 P ABC transporter (Permease
KLGGCMCB_00921 6e-115 papP P ABC transporter (Permease
KLGGCMCB_00922 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KLGGCMCB_00923 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KLGGCMCB_00924 0.0 copA 3.6.3.54 P P-type ATPase
KLGGCMCB_00925 2.7e-73 copY K Copper transport repressor, CopY TcrY family
KLGGCMCB_00926 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KLGGCMCB_00927 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KLGGCMCB_00928 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KLGGCMCB_00929 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KLGGCMCB_00930 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KLGGCMCB_00931 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KLGGCMCB_00932 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KLGGCMCB_00933 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KLGGCMCB_00934 3.2e-56
KLGGCMCB_00935 0.0 ctpE P E1-E2 ATPase
KLGGCMCB_00936 2e-25
KLGGCMCB_00937 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KLGGCMCB_00938 9.7e-28 L transposase activity
KLGGCMCB_00939 2.7e-129 K transcriptional regulator, MerR family
KLGGCMCB_00940 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
KLGGCMCB_00941 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
KLGGCMCB_00942 7.4e-64 XK27_02560 S cog cog2151
KLGGCMCB_00943 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KLGGCMCB_00944 7.7e-227 ytfP S Flavoprotein
KLGGCMCB_00946 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KLGGCMCB_00947 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
KLGGCMCB_00948 2.7e-183 ecsB U ABC transporter
KLGGCMCB_00949 2.3e-133 ecsA V abc transporter atp-binding protein
KLGGCMCB_00950 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KLGGCMCB_00951 5.6e-12
KLGGCMCB_00952 2.6e-55 S CD20-like family
KLGGCMCB_00953 2.1e-106
KLGGCMCB_00954 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KLGGCMCB_00955 6.9e-206 ylbM S Belongs to the UPF0348 family
KLGGCMCB_00956 2e-140 yqeM Q Methyltransferase domain protein
KLGGCMCB_00957 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KLGGCMCB_00958 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KLGGCMCB_00959 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLGGCMCB_00960 3.5e-49 yhbY J RNA-binding protein
KLGGCMCB_00961 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KLGGCMCB_00962 1.8e-98 yqeG S hydrolase of the HAD superfamily
KLGGCMCB_00963 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KLGGCMCB_00964 1.3e-57
KLGGCMCB_00965 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLGGCMCB_00966 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KLGGCMCB_00967 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLGGCMCB_00968 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KLGGCMCB_00969 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KLGGCMCB_00970 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KLGGCMCB_00971 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLGGCMCB_00972 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
KLGGCMCB_00973 6.8e-101 pncA Q isochorismatase
KLGGCMCB_00974 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KLGGCMCB_00975 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KLGGCMCB_00976 2.4e-75 XK27_03180 T universal stress protein
KLGGCMCB_00979 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLGGCMCB_00980 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KLGGCMCB_00981 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KLGGCMCB_00982 0.0 yjcE P NhaP-type Na H and K H antiporters
KLGGCMCB_00984 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
KLGGCMCB_00985 1.3e-184 yhcC S radical SAM protein
KLGGCMCB_00986 2.2e-196 ylbL T Belongs to the peptidase S16 family
KLGGCMCB_00987 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLGGCMCB_00988 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
KLGGCMCB_00989 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KLGGCMCB_00990 1.5e-09 S Protein of unknown function (DUF4059)
KLGGCMCB_00991 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
KLGGCMCB_00992 4.7e-163 yxeN P ABC transporter (Permease
KLGGCMCB_00993 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KLGGCMCB_00995 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLGGCMCB_00996 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KLGGCMCB_00997 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
KLGGCMCB_00998 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLGGCMCB_00999 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
KLGGCMCB_01000 2.9e-87 D nuclear chromosome segregation
KLGGCMCB_01001 1.5e-127 ybbM S transport system, permease component
KLGGCMCB_01002 1.2e-117 ybbL S abc transporter atp-binding protein
KLGGCMCB_01003 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KLGGCMCB_01004 4.6e-140 cppA E CppA N-terminal
KLGGCMCB_01005 5e-44 V CAAX protease self-immunity
KLGGCMCB_01006 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KLGGCMCB_01007 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KLGGCMCB_01010 3e-47 spiA K sequence-specific DNA binding
KLGGCMCB_01011 2.9e-28 blpT
KLGGCMCB_01012 6.7e-98 blpT
KLGGCMCB_01013 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KLGGCMCB_01014 3.2e-42 L Transposase
KLGGCMCB_01015 1.9e-46 L transposase activity
KLGGCMCB_01016 7.4e-23 L Transposase
KLGGCMCB_01017 1.8e-56 L transposition
KLGGCMCB_01018 9.1e-83 L Integrase core domain protein
KLGGCMCB_01019 1e-102 L Transposase
KLGGCMCB_01020 2.6e-112 L Transposase
KLGGCMCB_01021 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLGGCMCB_01022 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLGGCMCB_01023 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KLGGCMCB_01024 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLGGCMCB_01025 1.1e-142 purR 2.4.2.7 F operon repressor
KLGGCMCB_01026 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
KLGGCMCB_01027 6.9e-173 rmuC S RmuC domain protein
KLGGCMCB_01028 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
KLGGCMCB_01029 8.6e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KLGGCMCB_01030 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KLGGCMCB_01032 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KLGGCMCB_01033 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KLGGCMCB_01034 1.6e-143 tatD L Hydrolase, tatd
KLGGCMCB_01035 7.2e-74 yccU S CoA-binding protein
KLGGCMCB_01036 4.8e-51 trxA O Belongs to the thioredoxin family
KLGGCMCB_01037 1.9e-141 S Macro domain protein
KLGGCMCB_01038 2e-09 L thioesterase
KLGGCMCB_01039 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
KLGGCMCB_01042 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KLGGCMCB_01043 2.7e-62 L Transposase
KLGGCMCB_01044 1e-13 rpmH J Ribosomal protein L34
KLGGCMCB_01045 2e-186 jag S RNA-binding protein
KLGGCMCB_01046 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLGGCMCB_01047 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KLGGCMCB_01048 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
KLGGCMCB_01049 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KLGGCMCB_01050 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLGGCMCB_01051 6.7e-81 amiA E transmembrane transport
KLGGCMCB_01052 4.2e-74 amiA E transmembrane transport
KLGGCMCB_01053 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KLGGCMCB_01054 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLGGCMCB_01055 3.5e-50 S Protein of unknown function (DUF3397)
KLGGCMCB_01056 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KLGGCMCB_01057 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
KLGGCMCB_01058 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
KLGGCMCB_01059 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLGGCMCB_01060 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KLGGCMCB_01061 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
KLGGCMCB_01062 4.3e-77 XK27_09620 S reductase
KLGGCMCB_01063 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
KLGGCMCB_01064 1.2e-131 XK27_09615 S PAS domain
KLGGCMCB_01065 1.9e-07 fnt P Formate nitrite transporter
KLGGCMCB_01066 6.4e-54 fnt P Formate nitrite transporter
KLGGCMCB_01067 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
KLGGCMCB_01068 2.8e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KLGGCMCB_01069 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KLGGCMCB_01070 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KLGGCMCB_01071 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KLGGCMCB_01072 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KLGGCMCB_01073 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KLGGCMCB_01074 1.6e-21 S glycolate biosynthetic process
KLGGCMCB_01075 1.5e-64 S phosphatase activity
KLGGCMCB_01076 2e-157 rrmA 2.1.1.187 Q methyltransferase
KLGGCMCB_01079 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KLGGCMCB_01080 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLGGCMCB_01081 2.4e-36 yeeD O sulfur carrier activity
KLGGCMCB_01082 1.8e-187 yeeE S Sulphur transport
KLGGCMCB_01083 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLGGCMCB_01084 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KLGGCMCB_01085 4.1e-09 S Domain of unknown function (DUF4651)
KLGGCMCB_01086 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KLGGCMCB_01087 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLGGCMCB_01088 1.8e-111 S CAAX amino terminal protease family protein
KLGGCMCB_01090 5e-67 V CAAX protease self-immunity
KLGGCMCB_01091 1.4e-33 V CAAX protease self-immunity
KLGGCMCB_01092 8.8e-27 lanR K sequence-specific DNA binding
KLGGCMCB_01093 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLGGCMCB_01094 7.7e-177 ytxK 2.1.1.72 L DNA methylase
KLGGCMCB_01095 6.8e-13 comGF U Putative Competence protein ComGF
KLGGCMCB_01096 4e-72 comGF U Competence protein ComGF
KLGGCMCB_01097 1.4e-15 NU Type II secretory pathway pseudopilin
KLGGCMCB_01098 1.8e-57 cglD NU Competence protein
KLGGCMCB_01099 8.5e-43 comGC U Required for transformation and DNA binding
KLGGCMCB_01100 9.2e-153 cglB NU type II secretion system
KLGGCMCB_01101 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KLGGCMCB_01102 2.9e-68 S cog cog4699
KLGGCMCB_01103 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLGGCMCB_01104 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLGGCMCB_01105 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLGGCMCB_01106 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLGGCMCB_01107 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KLGGCMCB_01108 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
KLGGCMCB_01109 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KLGGCMCB_01110 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KLGGCMCB_01111 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KLGGCMCB_01112 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
KLGGCMCB_01113 1.8e-57 asp S cog cog1302
KLGGCMCB_01114 3.2e-226 norN V Mate efflux family protein
KLGGCMCB_01115 1.9e-278 thrC 4.2.3.1 E Threonine synthase
KLGGCMCB_01116 1.9e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLGGCMCB_01117 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
KLGGCMCB_01118 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLGGCMCB_01119 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLGGCMCB_01120 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
KLGGCMCB_01121 0.0 pepO 3.4.24.71 O Peptidase family M13
KLGGCMCB_01122 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KLGGCMCB_01123 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KLGGCMCB_01124 1.3e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KLGGCMCB_01125 1.4e-54 treB 2.7.1.201 G PTS System
KLGGCMCB_01126 5.8e-21 treR K DNA-binding transcription factor activity
KLGGCMCB_01127 1.2e-85 treR K trehalose operon
KLGGCMCB_01128 3.3e-95 ywlG S Belongs to the UPF0340 family
KLGGCMCB_01131 2e-35 L PFAM Integrase, catalytic core
KLGGCMCB_01132 2e-94 L PFAM Integrase, catalytic core
KLGGCMCB_01133 3.3e-46 K Putative DNA-binding domain
KLGGCMCB_01134 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
KLGGCMCB_01135 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLGGCMCB_01136 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
KLGGCMCB_01141 1e-39
KLGGCMCB_01142 6.5e-31
KLGGCMCB_01143 5e-31 S Hypothetical protein (DUF2513)
KLGGCMCB_01144 7.7e-13
KLGGCMCB_01146 3.7e-216 S MvaI/BcnI restriction endonuclease family
KLGGCMCB_01148 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KLGGCMCB_01149 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
KLGGCMCB_01151 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
KLGGCMCB_01152 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
KLGGCMCB_01153 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
KLGGCMCB_01154 3.3e-09 L PFAM Integrase, catalytic core
KLGGCMCB_01155 1.8e-111 L PFAM Integrase, catalytic core
KLGGCMCB_01156 3.3e-62 rplQ J ribosomal protein l17
KLGGCMCB_01157 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLGGCMCB_01158 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLGGCMCB_01159 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLGGCMCB_01160 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KLGGCMCB_01161 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLGGCMCB_01162 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KLGGCMCB_01163 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KLGGCMCB_01164 4.4e-58 rplO J binds to the 23S rRNA
KLGGCMCB_01165 2.5e-23 rpmD J ribosomal protein l30
KLGGCMCB_01166 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLGGCMCB_01167 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KLGGCMCB_01168 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLGGCMCB_01169 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLGGCMCB_01170 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLGGCMCB_01171 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLGGCMCB_01172 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLGGCMCB_01173 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLGGCMCB_01174 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLGGCMCB_01175 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KLGGCMCB_01176 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLGGCMCB_01177 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLGGCMCB_01178 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KLGGCMCB_01179 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLGGCMCB_01180 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLGGCMCB_01181 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KLGGCMCB_01182 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KLGGCMCB_01183 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLGGCMCB_01184 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KLGGCMCB_01185 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KLGGCMCB_01186 0.0 XK27_09800 I Acyltransferase
KLGGCMCB_01187 1.7e-35 XK27_09805 S MORN repeat protein
KLGGCMCB_01188 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLGGCMCB_01189 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLGGCMCB_01190 1.5e-89 adk 2.7.4.3 F topology modulation protein
KLGGCMCB_01191 8.6e-127 Z012_04635 K sequence-specific DNA binding
KLGGCMCB_01193 6.3e-16 C Radical SAM
KLGGCMCB_01194 3.4e-191 C Radical SAM
KLGGCMCB_01195 3.9e-287 V ABC transporter transmembrane region
KLGGCMCB_01196 2.5e-89 K sequence-specific DNA binding
KLGGCMCB_01197 1e-36 L Replication initiation factor
KLGGCMCB_01198 1.4e-107 L Replication initiation factor
KLGGCMCB_01199 1.9e-18 S Domain of unknown function (DUF3173)
KLGGCMCB_01200 3.5e-216 int L Belongs to the 'phage' integrase family
KLGGCMCB_01202 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KLGGCMCB_01203 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KLGGCMCB_01204 2.8e-44 yrzL S Belongs to the UPF0297 family
KLGGCMCB_01205 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLGGCMCB_01206 4.2e-44 yrzB S Belongs to the UPF0473 family
KLGGCMCB_01207 6.6e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
KLGGCMCB_01208 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KLGGCMCB_01209 7.5e-14
KLGGCMCB_01210 2.6e-91 XK27_10930 K acetyltransferase
KLGGCMCB_01211 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLGGCMCB_01212 2.3e-41 yaaA S Belongs to the UPF0246 family
KLGGCMCB_01213 1.2e-50 yaaA S Belongs to the UPF0246 family
KLGGCMCB_01214 9.9e-169 XK27_01785 S cog cog1284
KLGGCMCB_01215 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KLGGCMCB_01217 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
KLGGCMCB_01218 5.7e-52 metE 2.1.1.14 E Methionine synthase
KLGGCMCB_01219 7.6e-64 metE 2.1.1.14 E Methionine synthase
KLGGCMCB_01220 9.2e-36 metE 2.1.1.14 E Methionine synthase
KLGGCMCB_01221 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KLGGCMCB_01222 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLGGCMCB_01224 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
KLGGCMCB_01225 2.7e-95 S Hydrophobic domain protein
KLGGCMCB_01227 3.7e-27 S Membrane
KLGGCMCB_01228 3.1e-101
KLGGCMCB_01229 1.8e-23 S Small integral membrane protein
KLGGCMCB_01230 1.1e-71 M Protein conserved in bacteria
KLGGCMCB_01231 4.9e-12 K CsbD-like
KLGGCMCB_01232 3.5e-97 nudL L hydrolase
KLGGCMCB_01233 3.4e-13 nudL L hydrolase
KLGGCMCB_01234 4e-19 K negative regulation of transcription, DNA-templated
KLGGCMCB_01235 1.7e-23 K negative regulation of transcription, DNA-templated
KLGGCMCB_01237 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
KLGGCMCB_01238 1.8e-88 S Putative adhesin
KLGGCMCB_01239 3.9e-161 XK27_06930 V domain protein
KLGGCMCB_01240 6.4e-96 XK27_06935 K transcriptional regulator
KLGGCMCB_01241 4.8e-55 ypaA M Membrane
KLGGCMCB_01242 2.7e-08
KLGGCMCB_01243 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLGGCMCB_01244 8.2e-48 veg S Biofilm formation stimulator VEG
KLGGCMCB_01245 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KLGGCMCB_01246 3.9e-70 rplI J binds to the 23S rRNA
KLGGCMCB_01247 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KLGGCMCB_01248 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KLGGCMCB_01249 1.5e-77 F NUDIX domain
KLGGCMCB_01250 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KLGGCMCB_01251 0.0 S Bacterial membrane protein, YfhO
KLGGCMCB_01252 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
KLGGCMCB_01253 5.3e-85 lytE M LysM domain protein
KLGGCMCB_01254 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLGGCMCB_01255 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLGGCMCB_01256 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLGGCMCB_01257 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLGGCMCB_01258 6.3e-138 ymfM S sequence-specific DNA binding
KLGGCMCB_01259 3.1e-242 ymfH S Peptidase M16
KLGGCMCB_01260 4.8e-235 ymfF S Peptidase M16
KLGGCMCB_01261 1.6e-45 yaaA S S4 domain protein YaaA
KLGGCMCB_01262 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLGGCMCB_01263 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KLGGCMCB_01264 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KLGGCMCB_01265 4.2e-153 yvjA S membrane
KLGGCMCB_01266 6.7e-306 ybiT S abc transporter atp-binding protein
KLGGCMCB_01267 0.0 XK27_10405 S Bacterial membrane protein YfhO
KLGGCMCB_01271 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
KLGGCMCB_01272 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLGGCMCB_01273 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KLGGCMCB_01274 8.5e-134 parB K Belongs to the ParB family
KLGGCMCB_01275 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KLGGCMCB_01276 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KLGGCMCB_01277 1.1e-29 yyzM S Protein conserved in bacteria
KLGGCMCB_01278 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KLGGCMCB_01279 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KLGGCMCB_01280 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLGGCMCB_01281 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KLGGCMCB_01282 2.7e-61 divIC D Septum formation initiator
KLGGCMCB_01284 8.7e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KLGGCMCB_01285 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KLGGCMCB_01286 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLGGCMCB_01287 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLGGCMCB_01288 1.3e-137 L Transposase
KLGGCMCB_01294 2.6e-10
KLGGCMCB_01297 1.9e-07
KLGGCMCB_01302 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLGGCMCB_01303 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KLGGCMCB_01304 5.5e-36 XK27_02060 S Transglycosylase associated protein
KLGGCMCB_01305 1.7e-54 badR K DNA-binding transcription factor activity
KLGGCMCB_01306 1e-96 S reductase
KLGGCMCB_01307 2.3e-31 L Integrase core domain protein
KLGGCMCB_01308 6.2e-36 L transposition
KLGGCMCB_01309 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
KLGGCMCB_01310 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KLGGCMCB_01313 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KLGGCMCB_01314 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLGGCMCB_01315 1.1e-83 S Putative small multi-drug export protein
KLGGCMCB_01316 6.2e-76 ctsR K Belongs to the CtsR family
KLGGCMCB_01317 0.0 clpC O Belongs to the ClpA ClpB family
KLGGCMCB_01318 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLGGCMCB_01319 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLGGCMCB_01320 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLGGCMCB_01321 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KLGGCMCB_01322 6.9e-144 S SseB protein N-terminal domain
KLGGCMCB_01323 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
KLGGCMCB_01324 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLGGCMCB_01325 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KLGGCMCB_01328 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLGGCMCB_01329 3.5e-91 yacP S RNA-binding protein containing a PIN domain
KLGGCMCB_01330 3.4e-155 degV S DegV family
KLGGCMCB_01331 1.8e-31 K helix-turn-helix
KLGGCMCB_01332 6.1e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLGGCMCB_01333 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLGGCMCB_01334 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KLGGCMCB_01335 1.5e-35 K sequence-specific DNA binding
KLGGCMCB_01337 0.0 S Lantibiotic dehydratase, C terminus
KLGGCMCB_01338 2.4e-231 spaC2 V Lanthionine synthetase C family protein
KLGGCMCB_01339 4.3e-183 EGP Major facilitator Superfamily
KLGGCMCB_01340 5.9e-24 3.6.4.12
KLGGCMCB_01341 5.9e-91 3.6.4.12 K Divergent AAA domain protein
KLGGCMCB_01342 7.4e-225 int L Belongs to the 'phage' integrase family
KLGGCMCB_01343 1.8e-38 S Helix-turn-helix domain
KLGGCMCB_01344 4.9e-173
KLGGCMCB_01346 3.4e-75 isp2 S pathogenesis
KLGGCMCB_01347 5.7e-91 tnp L Transposase
KLGGCMCB_01348 3.3e-225 capA M Bacterial capsule synthesis protein
KLGGCMCB_01349 3.6e-39 gcvR T UPF0237 protein
KLGGCMCB_01350 1.9e-242 XK27_08635 S UPF0210 protein
KLGGCMCB_01351 2.2e-38 ais G alpha-ribazole phosphatase activity
KLGGCMCB_01352 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KLGGCMCB_01353 1.3e-102 acmA 3.2.1.17 NU amidase activity
KLGGCMCB_01354 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KLGGCMCB_01355 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLGGCMCB_01356 9.8e-298 dnaK O Heat shock 70 kDa protein
KLGGCMCB_01357 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KLGGCMCB_01358 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KLGGCMCB_01359 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KLGGCMCB_01360 1.7e-60 hmpT S membrane
KLGGCMCB_01361 2e-52 L Transposase
KLGGCMCB_01362 1.2e-165 L integrase core domain
KLGGCMCB_01363 1.6e-249 L Transposase
KLGGCMCB_01365 9.9e-19 S Domain of unknown function (DUF4649)
KLGGCMCB_01366 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KLGGCMCB_01367 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KLGGCMCB_01368 3.2e-86
KLGGCMCB_01369 1.6e-77 sigH K DNA-templated transcription, initiation
KLGGCMCB_01370 3.5e-149 ykuT M mechanosensitive ion channel
KLGGCMCB_01371 7.1e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLGGCMCB_01372 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KLGGCMCB_01373 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KLGGCMCB_01374 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
KLGGCMCB_01375 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KLGGCMCB_01376 2e-177 prmA J Ribosomal protein L11 methyltransferase
KLGGCMCB_01377 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KLGGCMCB_01378 1.4e-42 F nucleotide catabolic process
KLGGCMCB_01379 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KLGGCMCB_01380 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KLGGCMCB_01381 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KLGGCMCB_01382 1.8e-83 nrdI F Belongs to the NrdI family
KLGGCMCB_01383 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLGGCMCB_01384 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLGGCMCB_01385 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KLGGCMCB_01386 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KLGGCMCB_01387 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KLGGCMCB_01388 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KLGGCMCB_01389 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KLGGCMCB_01390 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLGGCMCB_01391 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KLGGCMCB_01392 6.5e-202 yhjX P Major Facilitator
KLGGCMCB_01393 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLGGCMCB_01394 5e-94 V VanZ like family
KLGGCMCB_01395 1e-123 glnQ E abc transporter atp-binding protein
KLGGCMCB_01396 5.8e-275 glnP P ABC transporter
KLGGCMCB_01397 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KLGGCMCB_01398 1.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KLGGCMCB_01399 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
KLGGCMCB_01400 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KLGGCMCB_01401 1.4e-234 sufD O assembly protein SufD
KLGGCMCB_01402 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLGGCMCB_01403 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
KLGGCMCB_01404 2.2e-273 sufB O assembly protein SufB
KLGGCMCB_01405 7e-10 oppA E ABC transporter substrate-binding protein
KLGGCMCB_01406 2e-138 oppA E ABC transporter substrate-binding protein
KLGGCMCB_01407 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLGGCMCB_01408 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLGGCMCB_01409 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLGGCMCB_01410 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLGGCMCB_01411 3e-27 oppD P Belongs to the ABC transporter superfamily
KLGGCMCB_01412 2.5e-32 oppD P Belongs to the ABC transporter superfamily
KLGGCMCB_01413 1.2e-62 oppD P Belongs to the ABC transporter superfamily
KLGGCMCB_01414 3.1e-43 oppD P Belongs to the ABC transporter superfamily
KLGGCMCB_01415 7.5e-62 oppF P Belongs to the ABC transporter superfamily
KLGGCMCB_01416 4.4e-62 oppF P Belongs to the ABC transporter superfamily
KLGGCMCB_01417 6.4e-23
KLGGCMCB_01418 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KLGGCMCB_01419 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLGGCMCB_01420 1.9e-223 EGP Major facilitator Superfamily
KLGGCMCB_01421 3.1e-72 adcR K transcriptional
KLGGCMCB_01422 2.2e-136 adcC P ABC transporter, ATP-binding protein
KLGGCMCB_01423 1.6e-127 adcB P ABC transporter (Permease
KLGGCMCB_01424 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KLGGCMCB_01425 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KLGGCMCB_01426 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
KLGGCMCB_01427 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KLGGCMCB_01428 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KLGGCMCB_01429 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
KLGGCMCB_01430 1.9e-127 yeeN K transcriptional regulatory protein
KLGGCMCB_01431 9.8e-50 yajC U protein transport
KLGGCMCB_01432 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLGGCMCB_01433 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KLGGCMCB_01434 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KLGGCMCB_01435 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KLGGCMCB_01436 0.0 WQ51_06230 S ABC transporter substrate binding protein
KLGGCMCB_01437 5.2e-142 cmpC S abc transporter atp-binding protein
KLGGCMCB_01438 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLGGCMCB_01439 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLGGCMCB_01440 4.4e-37 L Transposase
KLGGCMCB_01441 6.4e-18 L transposase activity
KLGGCMCB_01444 4.7e-43
KLGGCMCB_01445 6.8e-56 S TM2 domain
KLGGCMCB_01446 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLGGCMCB_01447 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLGGCMCB_01448 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
KLGGCMCB_01449 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KLGGCMCB_01450 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KLGGCMCB_01451 6e-55 cof Q phosphatase activity
KLGGCMCB_01452 6.2e-35 cof Q phosphatase activity
KLGGCMCB_01453 1.6e-137 glcR K transcriptional regulator (DeoR family)
KLGGCMCB_01454 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLGGCMCB_01455 3.8e-40 K transcriptional
KLGGCMCB_01457 2.6e-76 S thiolester hydrolase activity
KLGGCMCB_01458 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
KLGGCMCB_01459 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLGGCMCB_01460 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KLGGCMCB_01461 1.9e-77 yhaI L Membrane
KLGGCMCB_01462 5.1e-259 pepC 3.4.22.40 E aminopeptidase
KLGGCMCB_01463 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLGGCMCB_01464 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KLGGCMCB_01465 3.1e-95 ypsA S Belongs to the UPF0398 family
KLGGCMCB_01466 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KLGGCMCB_01467 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KLGGCMCB_01468 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KLGGCMCB_01469 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KLGGCMCB_01470 2.5e-23
KLGGCMCB_01471 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KLGGCMCB_01472 7.3e-80 XK27_09675 K -acetyltransferase
KLGGCMCB_01473 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KLGGCMCB_01474 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLGGCMCB_01475 5.2e-59 L Integrase core domain protein
KLGGCMCB_01476 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLGGCMCB_01477 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KLGGCMCB_01478 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLGGCMCB_01479 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KLGGCMCB_01480 8.8e-98 ybhL S Belongs to the BI1 family
KLGGCMCB_01483 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KLGGCMCB_01484 3.7e-91 K transcriptional regulator
KLGGCMCB_01485 7.6e-36 yneF S UPF0154 protein
KLGGCMCB_01486 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KLGGCMCB_01487 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLGGCMCB_01488 3.5e-99 XK27_09740 S Phosphoesterase
KLGGCMCB_01489 7.8e-85 ykuL S CBS domain
KLGGCMCB_01490 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KLGGCMCB_01491 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KLGGCMCB_01492 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KLGGCMCB_01493 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLGGCMCB_01494 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KLGGCMCB_01495 1.2e-258 trkH P Cation transport protein
KLGGCMCB_01496 1.5e-247 trkA P Potassium transporter peripheral membrane component
KLGGCMCB_01497 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KLGGCMCB_01498 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KLGGCMCB_01499 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KLGGCMCB_01500 5.6e-161 K sequence-specific DNA binding
KLGGCMCB_01501 1.2e-32 V protein secretion by the type I secretion system
KLGGCMCB_01502 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLGGCMCB_01503 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLGGCMCB_01504 1.6e-25 V protein secretion by the type I secretion system
KLGGCMCB_01505 1.8e-27 comA V protein secretion by the type I secretion system
KLGGCMCB_01506 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLGGCMCB_01507 3.7e-51 yhaI L Membrane
KLGGCMCB_01508 6.7e-36 S Domain of unknown function (DUF4173)
KLGGCMCB_01509 9.2e-132 S Domain of unknown function (DUF4173)
KLGGCMCB_01510 6.8e-95 ureI S AmiS/UreI family transporter
KLGGCMCB_01511 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KLGGCMCB_01512 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KLGGCMCB_01513 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KLGGCMCB_01514 6.6e-78 ureE O enzyme active site formation
KLGGCMCB_01515 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KLGGCMCB_01516 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KLGGCMCB_01517 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KLGGCMCB_01518 2.7e-177 cbiM P PDGLE domain
KLGGCMCB_01519 1.1e-136 P cobalt transport protein
KLGGCMCB_01520 1.6e-131 cbiO P ABC transporter
KLGGCMCB_01521 5.3e-153 ET amino acid transport
KLGGCMCB_01522 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLGGCMCB_01523 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KLGGCMCB_01524 3.8e-205 EGP Transmembrane secretion effector
KLGGCMCB_01525 1.8e-153 ET amino acid transport
KLGGCMCB_01526 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
KLGGCMCB_01527 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KLGGCMCB_01528 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KLGGCMCB_01529 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KLGGCMCB_01530 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLGGCMCB_01531 5.2e-98 metI P ABC transporter (Permease
KLGGCMCB_01532 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KLGGCMCB_01533 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KLGGCMCB_01534 8e-94 S UPF0397 protein
KLGGCMCB_01535 0.0 ykoD P abc transporter atp-binding protein
KLGGCMCB_01536 1.2e-146 cbiQ P cobalt transport
KLGGCMCB_01537 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KLGGCMCB_01538 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
KLGGCMCB_01539 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
KLGGCMCB_01540 1.2e-244 P COG0168 Trk-type K transport systems, membrane components
KLGGCMCB_01541 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KLGGCMCB_01542 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
KLGGCMCB_01543 3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLGGCMCB_01544 2.8e-282 T PhoQ Sensor
KLGGCMCB_01545 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLGGCMCB_01546 6.5e-218 dnaB L Replication initiation and membrane attachment
KLGGCMCB_01547 4.4e-166 dnaI L Primosomal protein DnaI
KLGGCMCB_01548 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KLGGCMCB_01550 1.2e-34
KLGGCMCB_01551 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
KLGGCMCB_01552 3e-27 L Integrase core domain protein
KLGGCMCB_01553 3.4e-50 L transposition
KLGGCMCB_01554 5.7e-23 L Transposase
KLGGCMCB_01555 7.8e-28 L transposase activity
KLGGCMCB_01556 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLGGCMCB_01557 4.2e-62 manO S protein conserved in bacteria
KLGGCMCB_01558 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
KLGGCMCB_01559 2.3e-116 manM G pts system
KLGGCMCB_01560 1.1e-181 manL 2.7.1.191 G pts system
KLGGCMCB_01561 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KLGGCMCB_01562 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KLGGCMCB_01563 1.9e-248 pbuO S permease
KLGGCMCB_01564 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KLGGCMCB_01565 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
KLGGCMCB_01566 2.5e-220 brpA K Transcriptional
KLGGCMCB_01567 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KLGGCMCB_01568 3.1e-212 nusA K Participates in both transcription termination and antitermination
KLGGCMCB_01569 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KLGGCMCB_01570 2e-46 ylxQ J ribosomal protein
KLGGCMCB_01571 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLGGCMCB_01572 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KLGGCMCB_01573 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
KLGGCMCB_01574 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
KLGGCMCB_01575 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KLGGCMCB_01576 6.2e-85 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KLGGCMCB_01577 3.2e-49 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KLGGCMCB_01578 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLGGCMCB_01579 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KLGGCMCB_01580 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KLGGCMCB_01581 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
KLGGCMCB_01582 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KLGGCMCB_01585 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLGGCMCB_01586 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLGGCMCB_01587 1.2e-74 ylbF S Belongs to the UPF0342 family
KLGGCMCB_01588 7.1e-46 ylbG S UPF0298 protein
KLGGCMCB_01589 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KLGGCMCB_01590 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KLGGCMCB_01591 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
KLGGCMCB_01592 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KLGGCMCB_01593 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KLGGCMCB_01594 6.8e-69 acuB S IMP dehydrogenase activity
KLGGCMCB_01595 8.9e-41 acuB S IMP dehydrogenase activity
KLGGCMCB_01596 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLGGCMCB_01597 1.1e-110 yvyE 3.4.13.9 S YigZ family
KLGGCMCB_01598 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KLGGCMCB_01599 1.7e-122 comFC S Competence protein
KLGGCMCB_01600 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLGGCMCB_01607 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KLGGCMCB_01608 6.4e-108 S Domain of unknown function (DUF1803)
KLGGCMCB_01609 7.8e-102 ygaC J Belongs to the UPF0374 family
KLGGCMCB_01610 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
KLGGCMCB_01611 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLGGCMCB_01612 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
KLGGCMCB_01613 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
KLGGCMCB_01614 1.9e-115 S Haloacid dehalogenase-like hydrolase
KLGGCMCB_01615 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KLGGCMCB_01616 4e-72 marR K Transcriptional regulator, MarR family
KLGGCMCB_01617 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLGGCMCB_01618 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLGGCMCB_01619 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KLGGCMCB_01620 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KLGGCMCB_01621 1.6e-126 IQ reductase
KLGGCMCB_01622 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KLGGCMCB_01623 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KLGGCMCB_01624 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLGGCMCB_01625 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KLGGCMCB_01626 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KLGGCMCB_01627 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KLGGCMCB_01628 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KLGGCMCB_01629 1.1e-65 tnp L Transposase
KLGGCMCB_01630 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
KLGGCMCB_01631 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
KLGGCMCB_01632 4.7e-27 L Transposase and inactivated derivatives, TnpA family
KLGGCMCB_01633 3.4e-126 tnp L Transposase
KLGGCMCB_01635 8e-277 S Protein of unknown function (DUF3114)
KLGGCMCB_01636 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
KLGGCMCB_01637 7.7e-198 V (ABC) transporter
KLGGCMCB_01638 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
KLGGCMCB_01639 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
KLGGCMCB_01640 1.1e-113 K sequence-specific DNA binding
KLGGCMCB_01641 8.4e-155 L COG2801 Transposase and inactivated derivatives
KLGGCMCB_01642 6.6e-38 L transposase activity
KLGGCMCB_01643 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
KLGGCMCB_01644 1.8e-84 L Transposase
KLGGCMCB_01645 5.5e-122 fruR K transcriptional
KLGGCMCB_01646 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KLGGCMCB_01647 0.0 fruA 2.7.1.202 G phosphotransferase system
KLGGCMCB_01648 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLGGCMCB_01649 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLGGCMCB_01651 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KLGGCMCB_01652 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLGGCMCB_01653 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KLGGCMCB_01654 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KLGGCMCB_01655 6.4e-29 2.3.1.128 K acetyltransferase
KLGGCMCB_01656 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KLGGCMCB_01657 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KLGGCMCB_01658 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KLGGCMCB_01659 2.6e-64 WQ51_03320 S cog cog4835
KLGGCMCB_01660 9.8e-91 XK27_08360 S EDD domain protein, DegV family
KLGGCMCB_01661 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLGGCMCB_01662 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KLGGCMCB_01663 0.0 yfmR S abc transporter atp-binding protein
KLGGCMCB_01664 1.6e-24 U response to pH
KLGGCMCB_01665 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KLGGCMCB_01666 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KLGGCMCB_01667 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KLGGCMCB_01668 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KLGGCMCB_01669 9.4e-77 K DNA-binding transcription factor activity
KLGGCMCB_01670 0.0 lmrA1 V abc transporter atp-binding protein
KLGGCMCB_01671 0.0 lmrA2 V abc transporter atp-binding protein
KLGGCMCB_01672 5.4e-45 K Acetyltransferase (GNAT) family
KLGGCMCB_01673 3.2e-78 sptS 2.7.13.3 T Histidine kinase
KLGGCMCB_01674 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KLGGCMCB_01675 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KLGGCMCB_01676 5.3e-161 cvfB S Protein conserved in bacteria
KLGGCMCB_01677 7.4e-35 yozE S Belongs to the UPF0346 family
KLGGCMCB_01678 6.7e-124 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
KLGGCMCB_01679 2.3e-61 rlpA M LysM domain protein
KLGGCMCB_01680 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
KLGGCMCB_01684 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLGGCMCB_01685 1.8e-164 K transcriptional regulator (lysR family)
KLGGCMCB_01686 1.4e-186 coiA 3.6.4.12 S Competence protein
KLGGCMCB_01687 0.0 pepF E oligoendopeptidase F
KLGGCMCB_01688 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
KLGGCMCB_01689 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KLGGCMCB_01690 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLGGCMCB_01691 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KLGGCMCB_01692 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KLGGCMCB_01693 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
KLGGCMCB_01694 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KLGGCMCB_01695 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KLGGCMCB_01696 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KLGGCMCB_01697 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KLGGCMCB_01698 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KLGGCMCB_01699 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KLGGCMCB_01700 2.2e-130 yxkH G deacetylase
KLGGCMCB_01701 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KLGGCMCB_01702 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KLGGCMCB_01703 5.5e-153 rarD S Transporter
KLGGCMCB_01704 2.2e-15 T peptidase
KLGGCMCB_01705 8.9e-14 coiA 3.6.4.12 S Competence protein
KLGGCMCB_01706 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KLGGCMCB_01707 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KLGGCMCB_01708 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KLGGCMCB_01709 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLGGCMCB_01710 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KLGGCMCB_01711 3.3e-78 atpF C ATP synthase F(0) sector subunit b
KLGGCMCB_01712 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLGGCMCB_01713 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLGGCMCB_01714 7.4e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLGGCMCB_01715 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLGGCMCB_01716 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KLGGCMCB_01717 2.8e-230 ftsW D Belongs to the SEDS family
KLGGCMCB_01718 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLGGCMCB_01719 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLGGCMCB_01720 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLGGCMCB_01721 1.9e-161 holB 2.7.7.7 L dna polymerase iii
KLGGCMCB_01722 2.1e-135 yaaT S stage 0 sporulation protein
KLGGCMCB_01723 1.1e-34 yabA L Involved in initiation control of chromosome replication
KLGGCMCB_01724 3.9e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLGGCMCB_01725 7.5e-233 amt P Ammonium Transporter
KLGGCMCB_01726 1.1e-53 glnB K Belongs to the P(II) protein family
KLGGCMCB_01727 4.9e-106 mur1 NU mannosyl-glycoprotein
KLGGCMCB_01728 1.7e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KLGGCMCB_01729 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
KLGGCMCB_01730 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KLGGCMCB_01731 1.8e-53
KLGGCMCB_01732 7.5e-26
KLGGCMCB_01733 1.5e-59
KLGGCMCB_01734 6.1e-63 S membrane
KLGGCMCB_01735 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KLGGCMCB_01736 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KLGGCMCB_01737 4.5e-39 ynzC S UPF0291 protein
KLGGCMCB_01738 1.8e-254 cycA E permease
KLGGCMCB_01739 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
KLGGCMCB_01740 2.8e-24 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KLGGCMCB_01741 5.8e-71 pts33BCA G pts system
KLGGCMCB_01742 9e-96 pts33BCA G pts system
KLGGCMCB_01743 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
KLGGCMCB_01744 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLGGCMCB_01749 1.4e-167 fhuR K transcriptional regulator (lysR family)
KLGGCMCB_01750 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KLGGCMCB_01751 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLGGCMCB_01752 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KLGGCMCB_01753 4.9e-227 pyrP F uracil Permease
KLGGCMCB_01754 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KLGGCMCB_01755 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KLGGCMCB_01756 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KLGGCMCB_01757 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
KLGGCMCB_01758 4e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KLGGCMCB_01759 1.6e-33 V permease protein
KLGGCMCB_01760 1e-09 V permease protein
KLGGCMCB_01761 8.8e-21 V permease protein
KLGGCMCB_01762 1.7e-07 V efflux transmembrane transporter activity
KLGGCMCB_01763 1.1e-24 ytrF V efflux transmembrane transporter activity
KLGGCMCB_01764 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLGGCMCB_01765 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KLGGCMCB_01767 0.0 mdlB V abc transporter atp-binding protein
KLGGCMCB_01768 0.0 lmrA V abc transporter atp-binding protein
KLGGCMCB_01769 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KLGGCMCB_01770 5.8e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLGGCMCB_01771 6.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KLGGCMCB_01772 2.5e-132 rr02 KT response regulator
KLGGCMCB_01773 3.5e-202 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KLGGCMCB_01774 4.8e-168 V ABC transporter
KLGGCMCB_01775 5.4e-122 sagI S ABC-2 type transporter
KLGGCMCB_01776 4.5e-196 yceA S Belongs to the UPF0176 family
KLGGCMCB_01777 8e-28 XK27_00085 K Transcriptional
KLGGCMCB_01778 1.7e-23
KLGGCMCB_01779 1.2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
KLGGCMCB_01780 2.8e-112 S VIT family
KLGGCMCB_01781 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLGGCMCB_01782 2.4e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KLGGCMCB_01783 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
KLGGCMCB_01784 2e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KLGGCMCB_01785 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLGGCMCB_01786 8.8e-104 GBS0088 J protein conserved in bacteria
KLGGCMCB_01787 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KLGGCMCB_01788 1.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KLGGCMCB_01789 1.6e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
KLGGCMCB_01790 7.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KLGGCMCB_01791 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLGGCMCB_01792 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KLGGCMCB_01793 2.5e-21
KLGGCMCB_01794 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLGGCMCB_01796 3.5e-07 U protein secretion
KLGGCMCB_01797 2.5e-51 U protein secretion
KLGGCMCB_01798 7.4e-08 M Pilin isopeptide linkage domain protein
KLGGCMCB_01799 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KLGGCMCB_01800 1.5e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KLGGCMCB_01801 3.5e-49 XK27_13030
KLGGCMCB_01802 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLGGCMCB_01803 8.3e-55 S hydrolase activity, acting on ester bonds
KLGGCMCB_01804 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KLGGCMCB_01805 6.8e-164 S Protein of unknown function (DUF3114)
KLGGCMCB_01806 1.2e-22 S Protein of unknown function (DUF3114)
KLGGCMCB_01807 1.5e-118 yqfA K protein, Hemolysin III
KLGGCMCB_01808 1e-25 K hmm pf08876
KLGGCMCB_01809 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KLGGCMCB_01810 1.7e-218 mvaS 2.3.3.10 I synthase
KLGGCMCB_01811 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLGGCMCB_01812 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KLGGCMCB_01813 9.7e-22
KLGGCMCB_01814 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLGGCMCB_01815 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KLGGCMCB_01816 1.5e-250 mmuP E amino acid
KLGGCMCB_01817 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KLGGCMCB_01818 1.4e-29 S Domain of unknown function (DUF1912)
KLGGCMCB_01819 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
KLGGCMCB_01820 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KLGGCMCB_01821 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLGGCMCB_01822 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLGGCMCB_01823 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KLGGCMCB_01824 4.8e-16 S Protein of unknown function (DUF2969)
KLGGCMCB_01827 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
KLGGCMCB_01830 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
KLGGCMCB_01831 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
KLGGCMCB_01832 3.7e-70 M Pfam SNARE associated Golgi protein
KLGGCMCB_01833 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
KLGGCMCB_01834 1.6e-08 S oxidoreductase
KLGGCMCB_01835 9.3e-59 S oxidoreductase
KLGGCMCB_01836 9.7e-66 S oxidoreductase
KLGGCMCB_01837 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
KLGGCMCB_01838 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KLGGCMCB_01839 0.0 clpE O Belongs to the ClpA ClpB family
KLGGCMCB_01840 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KLGGCMCB_01841 1.3e-34 ykuJ S protein conserved in bacteria
KLGGCMCB_01842 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KLGGCMCB_01843 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
KLGGCMCB_01844 3.1e-78 feoA P FeoA domain protein
KLGGCMCB_01845 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KLGGCMCB_01846 1.5e-07
KLGGCMCB_01847 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KLGGCMCB_01848 2.2e-45 K sequence-specific DNA binding
KLGGCMCB_01849 1.5e-35 yugF I carboxylic ester hydrolase activity
KLGGCMCB_01850 7.5e-23 I Alpha/beta hydrolase family
KLGGCMCB_01851 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KLGGCMCB_01852 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KLGGCMCB_01853 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KLGGCMCB_01854 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLGGCMCB_01855 5.8e-64 licT K transcriptional antiterminator
KLGGCMCB_01856 6.8e-53 licT K transcriptional antiterminator
KLGGCMCB_01857 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLGGCMCB_01858 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KLGGCMCB_01859 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KLGGCMCB_01860 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KLGGCMCB_01861 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KLGGCMCB_01862 2.5e-220 mdtG EGP Major facilitator Superfamily
KLGGCMCB_01863 2e-33 secG U Preprotein translocase subunit SecG
KLGGCMCB_01864 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KLGGCMCB_01865 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KLGGCMCB_01866 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLGGCMCB_01867 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KLGGCMCB_01868 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KLGGCMCB_01869 4.4e-183 ccpA K Catabolite control protein A
KLGGCMCB_01870 2.8e-28 yyaQ S YjbR
KLGGCMCB_01871 6.6e-101 yyaQ V Protein conserved in bacteria
KLGGCMCB_01872 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KLGGCMCB_01873 1e-78 yueI S Protein of unknown function (DUF1694)
KLGGCMCB_01874 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KLGGCMCB_01875 2e-25 WQ51_00785
KLGGCMCB_01876 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KLGGCMCB_01877 2e-219 ywbD 2.1.1.191 J Methyltransferase
KLGGCMCB_01878 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KLGGCMCB_01879 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KLGGCMCB_01880 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KLGGCMCB_01881 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KLGGCMCB_01882 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KLGGCMCB_01883 3.2e-53 yheA S Belongs to the UPF0342 family
KLGGCMCB_01884 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLGGCMCB_01885 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KLGGCMCB_01886 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KLGGCMCB_01887 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
KLGGCMCB_01888 6.4e-252 msrR K Transcriptional regulator
KLGGCMCB_01889 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
KLGGCMCB_01890 2.4e-203 I acyl-CoA dehydrogenase
KLGGCMCB_01891 4.5e-97 mip S hydroperoxide reductase activity
KLGGCMCB_01892 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLGGCMCB_01893 8.9e-20
KLGGCMCB_01894 3.2e-46
KLGGCMCB_01895 1e-31 K Cro/C1-type HTH DNA-binding domain
KLGGCMCB_01896 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KLGGCMCB_01897 9.7e-34 estA E GDSL-like Lipase/Acylhydrolase
KLGGCMCB_01898 1.1e-94
KLGGCMCB_01899 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KLGGCMCB_01900 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLGGCMCB_01901 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLGGCMCB_01902 2.6e-194 S CRISPR-associated protein Csn2 subfamily St
KLGGCMCB_01903 2.7e-146 ycgQ S TIGR03943 family
KLGGCMCB_01904 4.6e-155 XK27_03015 S permease
KLGGCMCB_01906 0.0 yhgF K Transcriptional accessory protein
KLGGCMCB_01907 9.9e-42 pspC KT PspC domain
KLGGCMCB_01908 2e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KLGGCMCB_01909 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KLGGCMCB_01911 5.5e-69 ytxH S General stress protein
KLGGCMCB_01913 2e-177 yegQ O Peptidase U32
KLGGCMCB_01914 3.4e-252 yegQ O Peptidase U32
KLGGCMCB_01915 8.1e-46 S CHY zinc finger
KLGGCMCB_01916 8.4e-88 bioY S biotin synthase
KLGGCMCB_01918 1.1e-33 XK27_12190 S protein conserved in bacteria
KLGGCMCB_01919 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
KLGGCMCB_01920 4.8e-11
KLGGCMCB_01921 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KLGGCMCB_01922 4.1e-225 mutH L DNA mismatch repair enzyme MutH
KLGGCMCB_01923 5.2e-29 S SIR2-like domain
KLGGCMCB_01924 1.2e-33 S SIR2-like domain
KLGGCMCB_01925 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KLGGCMCB_01926 6.4e-158 M LysM domain
KLGGCMCB_01927 7.6e-16
KLGGCMCB_01928 2.3e-175 S hydrolase
KLGGCMCB_01929 1.9e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KLGGCMCB_01930 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KLGGCMCB_01931 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KLGGCMCB_01932 2.7e-27 P Hemerythrin HHE cation binding domain protein
KLGGCMCB_01933 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KLGGCMCB_01934 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
KLGGCMCB_01935 3.9e-290 hsdM 2.1.1.72 V N-6 DNA Methylase
KLGGCMCB_01936 2.2e-147 3.1.21.3 V type I restriction modification DNA specificity domain
KLGGCMCB_01938 2.5e-44
KLGGCMCB_01939 3e-38
KLGGCMCB_01940 2.3e-171 spd F DNA RNA non-specific endonuclease
KLGGCMCB_01941 1.5e-92 lemA S LemA family
KLGGCMCB_01942 1.8e-135 htpX O Belongs to the peptidase M48B family
KLGGCMCB_01943 4.2e-75 S Psort location CytoplasmicMembrane, score
KLGGCMCB_01944 6.2e-56 S Domain of unknown function (DUF4430)
KLGGCMCB_01945 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KLGGCMCB_01946 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
KLGGCMCB_01947 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KLGGCMCB_01948 1.9e-23 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)