ORF_ID e_value Gene_name EC_number CAZy COGs Description
OFODALGK_00011 5.3e-11
OFODALGK_00017 5.5e-139 mreC M Involved in formation and maintenance of cell shape
OFODALGK_00018 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OFODALGK_00019 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
OFODALGK_00020 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OFODALGK_00021 2.9e-218 araT 2.6.1.1 E Aminotransferase
OFODALGK_00022 2.6e-143 recO L Involved in DNA repair and RecF pathway recombination
OFODALGK_00023 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OFODALGK_00024 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OFODALGK_00025 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OFODALGK_00026 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OFODALGK_00027 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OFODALGK_00028 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OFODALGK_00029 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OFODALGK_00030 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OFODALGK_00031 6.1e-79 L transposase activity
OFODALGK_00032 1.3e-49 L transposition
OFODALGK_00033 6.3e-34 L Integrase core domain protein
OFODALGK_00034 2.3e-161 S CHAP domain
OFODALGK_00035 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
OFODALGK_00036 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OFODALGK_00037 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OFODALGK_00038 9.2e-141 1.1.1.169 H Ketopantoate reductase
OFODALGK_00039 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OFODALGK_00040 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
OFODALGK_00041 1.2e-09 L Transposase
OFODALGK_00042 7.8e-211 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OFODALGK_00043 8.3e-221 nodC 2.4.1.212 GT2 M Chitin synthase
OFODALGK_00044 2.7e-146 ycgQ S TIGR03943 family
OFODALGK_00045 4.6e-155 XK27_03015 S permease
OFODALGK_00047 0.0 yhgF K Transcriptional accessory protein
OFODALGK_00048 9.9e-42 pspC KT PspC domain
OFODALGK_00049 2e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OFODALGK_00050 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OFODALGK_00052 5.5e-69 ytxH S General stress protein
OFODALGK_00054 2e-177 yegQ O Peptidase U32
OFODALGK_00055 3.4e-252 yegQ O Peptidase U32
OFODALGK_00056 8.1e-46 S CHY zinc finger
OFODALGK_00057 8.4e-88 bioY S biotin synthase
OFODALGK_00059 1.1e-33 XK27_12190 S protein conserved in bacteria
OFODALGK_00060 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
OFODALGK_00061 4.8e-11
OFODALGK_00062 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
OFODALGK_00063 4.1e-225 mutH L DNA mismatch repair enzyme MutH
OFODALGK_00064 5.2e-29 S SIR2-like domain
OFODALGK_00066 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OFODALGK_00067 6.4e-158 M LysM domain
OFODALGK_00068 7.6e-16
OFODALGK_00069 2.3e-175 S hydrolase
OFODALGK_00070 1.9e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
OFODALGK_00071 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OFODALGK_00072 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
OFODALGK_00073 2.7e-27 P Hemerythrin HHE cation binding domain protein
OFODALGK_00074 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFODALGK_00075 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
OFODALGK_00076 3.9e-290 hsdM 2.1.1.72 V N-6 DNA Methylase
OFODALGK_00077 2.2e-147 3.1.21.3 V type I restriction modification DNA specificity domain
OFODALGK_00079 2.5e-44
OFODALGK_00080 3e-38
OFODALGK_00081 2.3e-171 spd F DNA RNA non-specific endonuclease
OFODALGK_00082 1.5e-92 lemA S LemA family
OFODALGK_00083 1.8e-135 htpX O Belongs to the peptidase M48B family
OFODALGK_00084 4.2e-75 S Psort location CytoplasmicMembrane, score
OFODALGK_00085 6.2e-56 S Domain of unknown function (DUF4430)
OFODALGK_00086 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OFODALGK_00087 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
OFODALGK_00088 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
OFODALGK_00089 1.9e-23 L Transposase
OFODALGK_00090 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
OFODALGK_00091 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
OFODALGK_00092 3.5e-91 dps P Belongs to the Dps family
OFODALGK_00093 1.1e-80 perR P Belongs to the Fur family
OFODALGK_00094 8.4e-28 yqgQ S protein conserved in bacteria
OFODALGK_00095 2.2e-179 glk 2.7.1.2 G Glucokinase
OFODALGK_00096 0.0 typA T GTP-binding protein TypA
OFODALGK_00098 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OFODALGK_00099 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OFODALGK_00100 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OFODALGK_00101 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OFODALGK_00102 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OFODALGK_00103 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OFODALGK_00104 6.8e-96 sepF D cell septum assembly
OFODALGK_00105 2.6e-34 yggT D integral membrane protein
OFODALGK_00106 4.2e-144 ylmH T S4 RNA-binding domain
OFODALGK_00107 1.8e-135 divIVA D Cell division protein DivIVA
OFODALGK_00108 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OFODALGK_00109 5.5e-30
OFODALGK_00110 8.4e-10
OFODALGK_00111 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
OFODALGK_00112 2e-45 rpmE2 J 50S ribosomal protein L31
OFODALGK_00113 8.3e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
OFODALGK_00114 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
OFODALGK_00115 8.9e-155 gst O Glutathione S-transferase
OFODALGK_00116 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OFODALGK_00117 4.5e-111 tdk 2.7.1.21 F thymidine kinase
OFODALGK_00118 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OFODALGK_00119 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OFODALGK_00120 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OFODALGK_00121 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OFODALGK_00122 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
OFODALGK_00123 8e-100 pvaA M lytic transglycosylase activity
OFODALGK_00124 0.0 yfiB1 V abc transporter atp-binding protein
OFODALGK_00125 0.0 XK27_10035 V abc transporter atp-binding protein
OFODALGK_00126 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
OFODALGK_00127 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFODALGK_00128 3.9e-237 dltB M Membrane protein involved in D-alanine export
OFODALGK_00129 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFODALGK_00130 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OFODALGK_00131 9.6e-32 L transposition
OFODALGK_00132 6.5e-54 L transposition
OFODALGK_00133 7.7e-19 L transposase activity
OFODALGK_00134 2.5e-40 L Transposase
OFODALGK_00135 0.0 3.6.3.8 P cation transport ATPase
OFODALGK_00136 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
OFODALGK_00138 2.3e-12
OFODALGK_00140 2e-296 S DNA primase
OFODALGK_00141 3e-164 KL Phage plasmid primase P4 family
OFODALGK_00142 2.4e-22
OFODALGK_00143 1.2e-14
OFODALGK_00147 1.8e-19 K Cro/C1-type HTH DNA-binding domain
OFODALGK_00148 1e-21 xre K transcriptional
OFODALGK_00149 6.9e-220 sip L Belongs to the 'phage' integrase family
OFODALGK_00151 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OFODALGK_00152 7.3e-166 metF 1.5.1.20 E reductase
OFODALGK_00153 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OFODALGK_00154 1.7e-94 panT S ECF transporter, substrate-specific component
OFODALGK_00155 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OFODALGK_00156 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
OFODALGK_00157 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
OFODALGK_00158 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFODALGK_00159 2.8e-40 T PhoQ Sensor
OFODALGK_00160 1.7e-43 T PhoQ Sensor
OFODALGK_00161 5.8e-79 T PhoQ Sensor
OFODALGK_00162 2.1e-30 rpsT J rRNA binding
OFODALGK_00163 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
OFODALGK_00164 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
OFODALGK_00165 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
OFODALGK_00166 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
OFODALGK_00167 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OFODALGK_00168 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OFODALGK_00169 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OFODALGK_00170 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OFODALGK_00171 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OFODALGK_00172 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
OFODALGK_00173 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
OFODALGK_00174 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OFODALGK_00175 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OFODALGK_00176 3.1e-81 ypmB S Protein conserved in bacteria
OFODALGK_00177 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OFODALGK_00178 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
OFODALGK_00179 1.5e-07
OFODALGK_00180 3e-13
OFODALGK_00181 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
OFODALGK_00182 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OFODALGK_00183 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
OFODALGK_00184 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OFODALGK_00185 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
OFODALGK_00186 4.2e-18 D nuclear chromosome segregation
OFODALGK_00187 1.5e-135 yejC S cyclic nucleotide-binding protein
OFODALGK_00188 1.2e-163 rapZ S Displays ATPase and GTPase activities
OFODALGK_00189 1.8e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OFODALGK_00190 8.7e-162 whiA K May be required for sporulation
OFODALGK_00191 8e-90 pepD E Dipeptidase
OFODALGK_00192 5.8e-41 pepD E dipeptidase activity
OFODALGK_00193 5.4e-32 cspD K Cold shock protein domain
OFODALGK_00194 0.0 copB 3.6.3.4 P P-type ATPase
OFODALGK_00195 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OFODALGK_00196 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OFODALGK_00197 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
OFODALGK_00198 4.8e-157 glcU U Glucose uptake
OFODALGK_00199 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
OFODALGK_00200 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
OFODALGK_00201 2.2e-101 XK27_10720 D peptidase activity
OFODALGK_00202 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
OFODALGK_00203 1.7e-08
OFODALGK_00205 1.2e-172 yeiH S Membrane
OFODALGK_00206 5.5e-119 mur1 NU muramidase
OFODALGK_00207 1.9e-83 L transposition
OFODALGK_00208 2.6e-166 cpsY K Transcriptional regulator
OFODALGK_00209 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OFODALGK_00210 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
OFODALGK_00211 2e-104 artQ P ABC transporter (Permease
OFODALGK_00212 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
OFODALGK_00213 1.1e-158 aatB ET ABC transporter substrate-binding protein
OFODALGK_00214 3.5e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFODALGK_00215 2.5e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFODALGK_00216 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
OFODALGK_00217 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
OFODALGK_00218 9.3e-20 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
OFODALGK_00219 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OFODALGK_00220 4.5e-126 gntR1 K transcriptional
OFODALGK_00221 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OFODALGK_00222 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OFODALGK_00223 4.1e-87 niaX
OFODALGK_00224 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
OFODALGK_00225 6.9e-127 K DNA-binding helix-turn-helix protein
OFODALGK_00226 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OFODALGK_00227 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OFODALGK_00228 4.1e-167 GK ROK family
OFODALGK_00229 8.3e-159 dprA LU DNA protecting protein DprA
OFODALGK_00230 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OFODALGK_00231 1.4e-150 S TraX protein
OFODALGK_00232 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFODALGK_00233 2.4e-251 T PhoQ Sensor
OFODALGK_00234 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OFODALGK_00235 1.1e-152 XK27_05470 E Methionine synthase
OFODALGK_00236 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OFODALGK_00237 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OFODALGK_00238 1.8e-51 IQ Acetoin reductase
OFODALGK_00239 3.9e-19 IQ Acetoin reductase
OFODALGK_00240 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OFODALGK_00241 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
OFODALGK_00244 1.3e-212 pqqE C radical SAM domain protein
OFODALGK_00245 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
OFODALGK_00246 6.6e-61 EGP Major facilitator Superfamily
OFODALGK_00247 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OFODALGK_00248 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
OFODALGK_00249 1.6e-197 L Transposase
OFODALGK_00250 6.4e-104 V ABC transporter (Permease
OFODALGK_00251 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFODALGK_00252 1.6e-10
OFODALGK_00253 1.2e-97 K Transcriptional regulator, TetR family
OFODALGK_00254 1.2e-158 czcD P cation diffusion facilitator family transporter
OFODALGK_00255 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OFODALGK_00256 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
OFODALGK_00257 6e-08 S Hydrolases of the alpha beta superfamily
OFODALGK_00258 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
OFODALGK_00259 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
OFODALGK_00262 2.6e-143 2.4.2.3 F Phosphorylase superfamily
OFODALGK_00263 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
OFODALGK_00264 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
OFODALGK_00265 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
OFODALGK_00266 6.6e-73 dinF V Mate efflux family protein
OFODALGK_00267 4.8e-41 dinF V Mate efflux family protein
OFODALGK_00269 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OFODALGK_00270 3.7e-190
OFODALGK_00273 1.3e-57 T Toxic component of a toxin-antitoxin (TA) module
OFODALGK_00275 8.2e-70 argR K Regulates arginine biosynthesis genes
OFODALGK_00276 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OFODALGK_00277 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OFODALGK_00278 7e-34 S Protein of unknown function (DUF3021)
OFODALGK_00279 1.2e-61 KT phosphorelay signal transduction system
OFODALGK_00281 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OFODALGK_00283 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OFODALGK_00284 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
OFODALGK_00285 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
OFODALGK_00286 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OFODALGK_00287 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
OFODALGK_00288 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
OFODALGK_00289 3.5e-28 3.4.13.21 I Protein conserved in bacteria
OFODALGK_00291 5.7e-118 S TraX protein
OFODALGK_00292 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
OFODALGK_00293 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OFODALGK_00294 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OFODALGK_00295 4.7e-143 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OFODALGK_00296 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OFODALGK_00297 6.8e-133 cas6 S Pfam:DUF2276
OFODALGK_00298 0.0 csm1 S CRISPR-associated protein Csm1 family
OFODALGK_00299 5.6e-62 csm2 L Pfam:DUF310
OFODALGK_00300 1.1e-116 csm3 L RAMP superfamily
OFODALGK_00301 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
OFODALGK_00302 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
OFODALGK_00303 2.1e-14 csm6 S Psort location Cytoplasmic, score
OFODALGK_00304 5.2e-74 csm6 S Psort location Cytoplasmic, score
OFODALGK_00305 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OFODALGK_00306 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OFODALGK_00307 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
OFODALGK_00309 2.5e-267 dtpT E transporter
OFODALGK_00310 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
OFODALGK_00311 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
OFODALGK_00312 1.8e-67 yecS P ABC transporter (Permease
OFODALGK_00314 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
OFODALGK_00315 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
OFODALGK_00316 5.4e-104 yfiF3 K sequence-specific DNA binding
OFODALGK_00317 1.9e-147 L Transposase
OFODALGK_00318 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OFODALGK_00319 1.8e-240 agcS E (Alanine) symporter
OFODALGK_00320 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OFODALGK_00321 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
OFODALGK_00322 1.8e-59 Q phosphatase activity
OFODALGK_00323 9.3e-62 S haloacid dehalogenase-like hydrolase
OFODALGK_00324 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OFODALGK_00325 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
OFODALGK_00326 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
OFODALGK_00327 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
OFODALGK_00328 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OFODALGK_00329 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OFODALGK_00330 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OFODALGK_00331 1.9e-43 yktA S Belongs to the UPF0223 family
OFODALGK_00332 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
OFODALGK_00333 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
OFODALGK_00334 3.3e-158 pstS P phosphate
OFODALGK_00335 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
OFODALGK_00336 2e-155 pstA P phosphate transport system permease
OFODALGK_00337 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OFODALGK_00338 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OFODALGK_00339 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
OFODALGK_00340 0.0 pepN 3.4.11.2 E aminopeptidase
OFODALGK_00341 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
OFODALGK_00342 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
OFODALGK_00343 1.1e-17
OFODALGK_00344 3.7e-09
OFODALGK_00345 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OFODALGK_00346 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
OFODALGK_00347 2.3e-23 L Transposase
OFODALGK_00348 4.6e-25 tatA U protein secretion
OFODALGK_00349 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OFODALGK_00350 1.1e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
OFODALGK_00351 5.6e-233 ycdB P peroxidase
OFODALGK_00352 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
OFODALGK_00353 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
OFODALGK_00354 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
OFODALGK_00355 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
OFODALGK_00356 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
OFODALGK_00357 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
OFODALGK_00358 1.9e-37 3.5.1.28 NU amidase activity
OFODALGK_00359 8.5e-266 3.5.1.28 NU amidase activity
OFODALGK_00360 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
OFODALGK_00361 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
OFODALGK_00362 0.0 lpdA 1.8.1.4 C Dehydrogenase
OFODALGK_00363 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OFODALGK_00364 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OFODALGK_00365 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
OFODALGK_00366 5e-38 P membrane protein (DUF2207)
OFODALGK_00367 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
OFODALGK_00368 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OFODALGK_00369 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OFODALGK_00370 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFODALGK_00371 1.2e-157 rssA S Phospholipase, patatin family
OFODALGK_00372 3.9e-78 estA E GDSL-like protein
OFODALGK_00373 2.6e-15 estA E Lysophospholipase L1 and related esterases
OFODALGK_00374 3.7e-293 S unusual protein kinase
OFODALGK_00375 4.9e-39 S granule-associated protein
OFODALGK_00376 7.9e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFODALGK_00377 5.8e-28 bglH 3.2.1.86 GT1 G beta-glucosidase activity
OFODALGK_00378 1.3e-199 S hmm pf01594
OFODALGK_00379 1.6e-44 G alpha-ribazole phosphatase activity
OFODALGK_00380 2e-33 G Belongs to the phosphoglycerate mutase family
OFODALGK_00381 1.1e-25 G Belongs to the phosphoglycerate mutase family
OFODALGK_00382 8.8e-66 pgm G Belongs to the phosphoglycerate mutase family
OFODALGK_00383 1.7e-80 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OFODALGK_00384 4.9e-94 V VanZ like family
OFODALGK_00385 6.4e-33 cpsJ S Glycosyltransferase like family 2
OFODALGK_00386 3e-15
OFODALGK_00387 1.1e-71 M Glycosyltransferase sugar-binding region containing DXD motif
OFODALGK_00388 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
OFODALGK_00389 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
OFODALGK_00390 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
OFODALGK_00391 3.3e-37 L transposase activity
OFODALGK_00392 4e-60 L COG2801 Transposase and inactivated derivatives
OFODALGK_00393 2.4e-30 tra981A L Integrase core domain
OFODALGK_00394 8.1e-52 tnp L DDE domain
OFODALGK_00395 1.4e-235 cps1C S Polysaccharide biosynthesis protein
OFODALGK_00396 9.1e-110 L Transposase
OFODALGK_00397 2.4e-93 L Transposase
OFODALGK_00398 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
OFODALGK_00399 3e-139 L Integrase core domain
OFODALGK_00400 2.2e-22 L Transposase
OFODALGK_00401 1.7e-27 tnp L DDE domain
OFODALGK_00402 8.5e-23 rgpAc GT4 M group 1 family protein
OFODALGK_00403 5.7e-250 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
OFODALGK_00404 5.3e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
OFODALGK_00405 2.6e-105 cps4C M biosynthesis protein
OFODALGK_00406 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
OFODALGK_00407 3.8e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
OFODALGK_00408 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
OFODALGK_00409 1.7e-48 yfeJ 6.3.5.2 F glutamine amidotransferase
OFODALGK_00410 2.5e-43 yfeJ 6.3.5.2 F glutamine amidotransferase
OFODALGK_00411 3.6e-40 clcA_2 P chloride
OFODALGK_00412 3.8e-42 clcA_2 P chloride channel
OFODALGK_00413 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OFODALGK_00414 9.3e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OFODALGK_00415 6.6e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OFODALGK_00417 4e-21 V Glucan-binding protein C
OFODALGK_00418 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
OFODALGK_00419 2.4e-275 pepV 3.5.1.18 E Dipeptidase
OFODALGK_00420 3.2e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
OFODALGK_00421 6.9e-86 XK27_03610 K Gnat family
OFODALGK_00422 9.1e-10 L COG1943 Transposase and inactivated derivatives
OFODALGK_00423 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OFODALGK_00424 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OFODALGK_00425 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OFODALGK_00426 2.8e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OFODALGK_00427 3.9e-15 M LysM domain
OFODALGK_00428 2.9e-90 ebsA S Family of unknown function (DUF5322)
OFODALGK_00429 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OFODALGK_00430 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
OFODALGK_00431 4.9e-224 G COG0457 FOG TPR repeat
OFODALGK_00432 1.1e-175 yubA S permease
OFODALGK_00433 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
OFODALGK_00434 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OFODALGK_00435 2.5e-124 ftsE D cell division ATP-binding protein FtsE
OFODALGK_00436 1.8e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OFODALGK_00437 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OFODALGK_00438 4.3e-180 yjjH S Calcineurin-like phosphoesterase
OFODALGK_00439 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
OFODALGK_00440 0.0 pacL 3.6.3.8 P cation transport ATPase
OFODALGK_00441 2.6e-67 ywiB S Domain of unknown function (DUF1934)
OFODALGK_00442 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
OFODALGK_00443 9.2e-147 yidA S hydrolases of the HAD superfamily
OFODALGK_00444 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
OFODALGK_00445 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
OFODALGK_00446 1.5e-247 vicK 2.7.13.3 T Histidine kinase
OFODALGK_00447 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFODALGK_00448 1e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
OFODALGK_00449 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
OFODALGK_00450 8e-115 gltJ P ABC transporter (Permease
OFODALGK_00451 4.2e-110 tcyB_2 P ABC transporter (permease)
OFODALGK_00452 1.4e-124 endA F DNA RNA non-specific endonuclease
OFODALGK_00453 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
OFODALGK_00454 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OFODALGK_00456 3.7e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OFODALGK_00457 4.9e-21 G Domain of unknown function (DUF4832)
OFODALGK_00458 8.4e-53 G Domain of unknown function (DUF4832)
OFODALGK_00459 1.5e-211 cotH M CotH kinase protein
OFODALGK_00460 6.8e-185 pelG M Putative exopolysaccharide Exporter (EPS-E)
OFODALGK_00461 1.9e-109 pelF GT4 M Domain of unknown function (DUF3492)
OFODALGK_00462 7.6e-160 pelF GT4 M Domain of unknown function (DUF3492)
OFODALGK_00463 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
OFODALGK_00464 4.1e-143
OFODALGK_00465 7.6e-134 5.1.3.2 GM Psort location CytoplasmicMembrane, score
OFODALGK_00466 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OFODALGK_00467 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OFODALGK_00468 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFODALGK_00469 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
OFODALGK_00470 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OFODALGK_00471 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
OFODALGK_00473 7.7e-35
OFODALGK_00476 7.8e-202 S Phage integrase family
OFODALGK_00478 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OFODALGK_00479 4.3e-133 XK27_05110 P chloride
OFODALGK_00480 1.2e-61 XK27_05110 P chloride
OFODALGK_00481 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
OFODALGK_00482 1.3e-282 clcA P Chloride transporter, ClC family
OFODALGK_00483 6.7e-75 fld C Flavodoxin
OFODALGK_00485 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
OFODALGK_00486 3.5e-151 estA CE1 S Putative esterase
OFODALGK_00487 1e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OFODALGK_00488 1.2e-135 XK27_08845 S abc transporter atp-binding protein
OFODALGK_00489 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
OFODALGK_00490 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
OFODALGK_00491 3.2e-17 S Domain of unknown function (DUF4649)
OFODALGK_00493 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
OFODALGK_00494 1.1e-22 Q the current gene model (or a revised gene model) may contain a frame shift
OFODALGK_00495 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
OFODALGK_00496 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OFODALGK_00497 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OFODALGK_00498 0.0 dnaE 2.7.7.7 L DNA polymerase
OFODALGK_00499 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
OFODALGK_00500 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OFODALGK_00501 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OFODALGK_00502 2.5e-43 ysdA L Membrane
OFODALGK_00503 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OFODALGK_00504 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OFODALGK_00505 3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OFODALGK_00506 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
OFODALGK_00508 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OFODALGK_00509 1.7e-83 ypmS S Protein conserved in bacteria
OFODALGK_00510 6e-144 ypmR E lipolytic protein G-D-S-L family
OFODALGK_00511 1e-148 DegV S DegV family
OFODALGK_00512 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
OFODALGK_00513 1.8e-72 argR K Regulates arginine biosynthesis genes
OFODALGK_00514 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
OFODALGK_00515 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OFODALGK_00516 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
OFODALGK_00517 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OFODALGK_00520 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OFODALGK_00521 2.9e-125 dnaD
OFODALGK_00522 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OFODALGK_00523 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OFODALGK_00524 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
OFODALGK_00525 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OFODALGK_00526 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OFODALGK_00527 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
OFODALGK_00528 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OFODALGK_00529 1.6e-239 rodA D Belongs to the SEDS family
OFODALGK_00530 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
OFODALGK_00531 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OFODALGK_00532 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OFODALGK_00533 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OFODALGK_00534 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OFODALGK_00535 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OFODALGK_00536 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OFODALGK_00537 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OFODALGK_00538 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OFODALGK_00539 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OFODALGK_00541 9.2e-26 L Integrase core domain protein
OFODALGK_00542 5.2e-36 L transposase activity
OFODALGK_00543 1.3e-22 XK27_08085
OFODALGK_00544 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
OFODALGK_00545 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
OFODALGK_00546 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
OFODALGK_00547 1.1e-121 ylfI S tigr01906
OFODALGK_00548 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OFODALGK_00549 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
OFODALGK_00550 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
OFODALGK_00553 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OFODALGK_00554 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
OFODALGK_00555 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OFODALGK_00556 1.1e-206 yurR 1.4.5.1 E oxidoreductase
OFODALGK_00557 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
OFODALGK_00558 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OFODALGK_00559 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
OFODALGK_00560 1.7e-70 gtrA S GtrA-like protein
OFODALGK_00561 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OFODALGK_00562 6e-169 ybbR S Protein conserved in bacteria
OFODALGK_00563 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OFODALGK_00564 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
OFODALGK_00565 8.7e-150 cobQ S glutamine amidotransferase
OFODALGK_00566 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OFODALGK_00567 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
OFODALGK_00568 0.0 uup S abc transporter atp-binding protein
OFODALGK_00569 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
OFODALGK_00570 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
OFODALGK_00571 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OFODALGK_00572 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
OFODALGK_00573 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OFODALGK_00574 7.9e-39 ptsH G phosphocarrier protein Hpr
OFODALGK_00575 3.3e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
OFODALGK_00576 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
OFODALGK_00577 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OFODALGK_00578 2.2e-34 nrdH O Glutaredoxin
OFODALGK_00579 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFODALGK_00580 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFODALGK_00582 4.2e-71 L Transposase (IS116 IS110 IS902 family)
OFODALGK_00583 3.3e-26 L Transposase (IS116 IS110 IS902 family)
OFODALGK_00584 1.2e-164 ypuA S secreted protein
OFODALGK_00585 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
OFODALGK_00586 5.1e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
OFODALGK_00587 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OFODALGK_00588 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OFODALGK_00589 3.4e-258 noxE P NADH oxidase
OFODALGK_00590 1.9e-294 yfmM S abc transporter atp-binding protein
OFODALGK_00591 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
OFODALGK_00592 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
OFODALGK_00593 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
OFODALGK_00594 2e-86 S ECF-type riboflavin transporter, S component
OFODALGK_00596 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFODALGK_00597 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
OFODALGK_00600 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OFODALGK_00601 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFODALGK_00602 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OFODALGK_00603 0.0 smc D Required for chromosome condensation and partitioning
OFODALGK_00604 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OFODALGK_00605 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OFODALGK_00606 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OFODALGK_00607 2.4e-92 pat 2.3.1.183 M acetyltransferase
OFODALGK_00608 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OFODALGK_00609 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OFODALGK_00610 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
OFODALGK_00611 1.2e-62 bioY S biotin transmembrane transporter activity
OFODALGK_00612 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
OFODALGK_00613 1.5e-138 proV E abc transporter atp-binding protein
OFODALGK_00614 4.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
OFODALGK_00615 3e-111 proWZ P ABC transporter (Permease
OFODALGK_00616 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
OFODALGK_00617 1.6e-205 S Protein of unknown function (DUF917)
OFODALGK_00618 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OFODALGK_00619 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
OFODALGK_00620 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFODALGK_00621 1.5e-192 desK 2.7.13.3 T Histidine kinase
OFODALGK_00622 1.4e-133 yvfS V ABC-2 type transporter
OFODALGK_00623 8.7e-159 XK27_09825 V abc transporter atp-binding protein
OFODALGK_00626 8.1e-163 yocS S Transporter
OFODALGK_00627 1.2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
OFODALGK_00628 7.5e-115 yvfS V Transporter
OFODALGK_00629 3.9e-151 XK27_09825 V abc transporter atp-binding protein
OFODALGK_00630 2.7e-14 liaI KT membrane
OFODALGK_00631 2.6e-30 liaI KT membrane
OFODALGK_00632 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
OFODALGK_00633 0.0 V ABC transporter (permease)
OFODALGK_00634 1.9e-133 macB2 V ABC transporter, ATP-binding protein
OFODALGK_00635 3.1e-165 T Histidine kinase
OFODALGK_00636 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFODALGK_00637 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OFODALGK_00638 3.3e-69 pbuX F xanthine permease
OFODALGK_00639 9.2e-119 pbuX F xanthine permease
OFODALGK_00640 1.5e-247 norM V Multidrug efflux pump
OFODALGK_00641 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OFODALGK_00642 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
OFODALGK_00643 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
OFODALGK_00644 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
OFODALGK_00645 4.8e-25 csbD K CsbD-like
OFODALGK_00646 6.2e-228 yfnA E amino acid
OFODALGK_00647 5.1e-110 XK27_02070 S nitroreductase
OFODALGK_00648 9.5e-150 1.13.11.2 S glyoxalase
OFODALGK_00649 5.6e-77 ywnA K Transcriptional regulator
OFODALGK_00650 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
OFODALGK_00651 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFODALGK_00652 1.4e-110 drgA C Nitroreductase
OFODALGK_00653 3e-102 yoaK S Protein of unknown function (DUF1275)
OFODALGK_00655 6.8e-161 yvgN C reductase
OFODALGK_00656 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OFODALGK_00657 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
OFODALGK_00659 1.1e-37 BP1961 P nitric oxide dioxygenase activity
OFODALGK_00660 1.4e-54 K response regulator
OFODALGK_00661 9.3e-72 S Signal peptide protein, YSIRK family
OFODALGK_00663 4.5e-61
OFODALGK_00664 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFODALGK_00665 1e-137
OFODALGK_00666 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
OFODALGK_00667 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
OFODALGK_00668 5.8e-109 MA20_06410 E LysE type translocator
OFODALGK_00669 5.6e-08
OFODALGK_00670 2.7e-09
OFODALGK_00671 0.0 M family 8
OFODALGK_00672 1.5e-162 hrtB V MacB-like periplasmic core domain
OFODALGK_00673 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
OFODALGK_00674 1.1e-151 V MatE
OFODALGK_00676 3.9e-110 C Fe-S oxidoreductases
OFODALGK_00677 3.6e-59 EGP Major Facilitator Superfamily
OFODALGK_00678 5.5e-258 I radical SAM domain protein
OFODALGK_00680 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
OFODALGK_00681 1.4e-150 L Integrase core domain protein
OFODALGK_00682 1.8e-87 L transposase activity
OFODALGK_00684 2.8e-85
OFODALGK_00685 0.0 sbcC L ATPase involved in DNA repair
OFODALGK_00686 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OFODALGK_00687 0.0 lacL 3.2.1.23 G -beta-galactosidase
OFODALGK_00688 0.0 lacS G transporter
OFODALGK_00689 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
OFODALGK_00690 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OFODALGK_00691 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
OFODALGK_00692 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OFODALGK_00693 2.3e-184 galR K Transcriptional regulator
OFODALGK_00694 2.7e-08 L Integrase core domain protein
OFODALGK_00695 1.2e-25 L transposition
OFODALGK_00696 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
OFODALGK_00697 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
OFODALGK_00698 2.5e-101 V abc transporter atp-binding protein
OFODALGK_00699 4.3e-40 V abc transporter atp-binding protein
OFODALGK_00700 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
OFODALGK_00701 6.4e-62 L Transposase
OFODALGK_00702 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
OFODALGK_00703 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
OFODALGK_00704 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
OFODALGK_00705 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OFODALGK_00706 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OFODALGK_00707 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OFODALGK_00708 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OFODALGK_00711 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFODALGK_00712 5.8e-175 vraS 2.7.13.3 T Histidine kinase
OFODALGK_00713 3.7e-120 yvqF KT membrane
OFODALGK_00714 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OFODALGK_00715 2e-132 stp 3.1.3.16 T phosphatase
OFODALGK_00716 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OFODALGK_00717 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OFODALGK_00718 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OFODALGK_00719 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
OFODALGK_00720 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OFODALGK_00721 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OFODALGK_00722 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
OFODALGK_00723 2.1e-148 supH S overlaps another CDS with the same product name
OFODALGK_00724 8.6e-63 yvoA_1 K Transcriptional
OFODALGK_00725 2.8e-120 skfE V abc transporter atp-binding protein
OFODALGK_00726 3.3e-133 V ATPase activity
OFODALGK_00727 4.3e-172 oppF P Belongs to the ABC transporter superfamily
OFODALGK_00728 2.2e-204 oppD P Belongs to the ABC transporter superfamily
OFODALGK_00729 4.9e-168 amiD P ABC transporter (Permease
OFODALGK_00730 4.2e-278 amiC P ABC transporter (Permease
OFODALGK_00731 3.7e-140 amiA E ABC transporter, substrate-binding protein, family 5
OFODALGK_00732 0.0 amiA E ABC transporter, substrate-binding protein, family 5
OFODALGK_00733 8.1e-45 L Transposase
OFODALGK_00734 4.1e-158 L COG2801 Transposase and inactivated derivatives
OFODALGK_00735 1.2e-24 oppF P Belongs to the ABC transporter superfamily
OFODALGK_00736 3.8e-45 oppF P Belongs to the ABC transporter superfamily
OFODALGK_00737 1.4e-40 tatD L Hydrolase, tatd
OFODALGK_00738 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
OFODALGK_00739 1e-110 L Integrase core domain protein
OFODALGK_00740 1.1e-23 L transposase activity
OFODALGK_00741 8.9e-18 L transposase activity
OFODALGK_00742 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
OFODALGK_00743 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
OFODALGK_00744 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OFODALGK_00745 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
OFODALGK_00746 1.5e-103 yjbK S Adenylate cyclase
OFODALGK_00747 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OFODALGK_00748 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
OFODALGK_00749 2e-58 XK27_04120 S Putative amino acid metabolism
OFODALGK_00750 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OFODALGK_00751 1.6e-131 puuD T peptidase C26
OFODALGK_00752 6.2e-120 radC E Belongs to the UPF0758 family
OFODALGK_00753 4.9e-272 rgpF M Rhamnan synthesis protein F
OFODALGK_00754 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OFODALGK_00755 6.4e-140 rgpC GM Transport permease protein
OFODALGK_00756 2e-169 rgpB GT2 M Glycosyltransferase, group 2 family protein
OFODALGK_00757 1.1e-222 rgpA GT4 M Domain of unknown function (DUF1972)
OFODALGK_00758 5e-174 S Glucosyl transferase GtrII
OFODALGK_00759 1.8e-28 S Glucosyl transferase GtrII
OFODALGK_00760 1.6e-219 GT4 M transferase activity, transferring glycosyl groups
OFODALGK_00761 2e-217 M Psort location CytoplasmicMembrane, score
OFODALGK_00762 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
OFODALGK_00763 5.9e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
OFODALGK_00764 4.6e-42 S Uncharacterized conserved protein (DUF2304)
OFODALGK_00765 4.2e-89 arnC M group 2 family protein
OFODALGK_00766 1.1e-181 cpsIaJ S Glycosyltransferase like family 2
OFODALGK_00767 1e-184 S Glycosyltransferase like family 2
OFODALGK_00768 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
OFODALGK_00769 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OFODALGK_00770 2.9e-235 S Predicted membrane protein (DUF2142)
OFODALGK_00771 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
OFODALGK_00772 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
OFODALGK_00773 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OFODALGK_00774 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OFODALGK_00775 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OFODALGK_00776 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
OFODALGK_00777 2.1e-202 arcT 2.6.1.1 E Aminotransferase
OFODALGK_00778 9.4e-136 ET ABC transporter
OFODALGK_00779 1.1e-142 ET Belongs to the bacterial solute-binding protein 3 family
OFODALGK_00780 2.9e-84 mutT 3.6.1.55 F Nudix family
OFODALGK_00781 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OFODALGK_00783 1.2e-55 V CAAX protease self-immunity
OFODALGK_00784 2.6e-32 S CAAX amino terminal protease family protein
OFODALGK_00785 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
OFODALGK_00786 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
OFODALGK_00787 2.4e-16 XK27_00735
OFODALGK_00788 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OFODALGK_00790 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OFODALGK_00793 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
OFODALGK_00794 6.6e-30 ycaO O OsmC-like protein
OFODALGK_00796 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
OFODALGK_00802 2.6e-10
OFODALGK_00805 1.9e-07
OFODALGK_00810 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFODALGK_00811 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OFODALGK_00812 5.5e-36 XK27_02060 S Transglycosylase associated protein
OFODALGK_00813 1.7e-54 badR K DNA-binding transcription factor activity
OFODALGK_00814 1e-96 S reductase
OFODALGK_00815 2.3e-31 L Integrase core domain protein
OFODALGK_00816 6.2e-36 L transposition
OFODALGK_00817 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
OFODALGK_00818 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OFODALGK_00821 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
OFODALGK_00822 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OFODALGK_00823 1.1e-83 S Putative small multi-drug export protein
OFODALGK_00824 6.2e-76 ctsR K Belongs to the CtsR family
OFODALGK_00825 0.0 clpC O Belongs to the ClpA ClpB family
OFODALGK_00826 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OFODALGK_00827 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OFODALGK_00828 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OFODALGK_00829 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OFODALGK_00830 6.9e-144 S SseB protein N-terminal domain
OFODALGK_00831 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
OFODALGK_00832 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFODALGK_00833 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OFODALGK_00836 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OFODALGK_00837 3.5e-91 yacP S RNA-binding protein containing a PIN domain
OFODALGK_00838 3.4e-155 degV S DegV family
OFODALGK_00839 1.8e-31 K helix-turn-helix
OFODALGK_00840 6.1e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OFODALGK_00841 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OFODALGK_00842 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
OFODALGK_00843 1.5e-35 K sequence-specific DNA binding
OFODALGK_00845 0.0 S Lantibiotic dehydratase, C terminus
OFODALGK_00846 2.4e-231 spaC2 V Lanthionine synthetase C family protein
OFODALGK_00847 4.3e-183 EGP Major facilitator Superfamily
OFODALGK_00848 5.9e-24 3.6.4.12
OFODALGK_00849 5.9e-91 3.6.4.12 K Divergent AAA domain protein
OFODALGK_00850 7.4e-225 int L Belongs to the 'phage' integrase family
OFODALGK_00851 1.8e-38 S Helix-turn-helix domain
OFODALGK_00852 4.9e-173
OFODALGK_00854 3.4e-75 isp2 S pathogenesis
OFODALGK_00855 5.7e-91 tnp L Transposase
OFODALGK_00856 3.3e-225 capA M Bacterial capsule synthesis protein
OFODALGK_00857 3.6e-39 gcvR T UPF0237 protein
OFODALGK_00858 1.9e-242 XK27_08635 S UPF0210 protein
OFODALGK_00859 2.2e-38 ais G alpha-ribazole phosphatase activity
OFODALGK_00860 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OFODALGK_00861 1.3e-102 acmA 3.2.1.17 NU amidase activity
OFODALGK_00862 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OFODALGK_00863 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OFODALGK_00864 9.8e-298 dnaK O Heat shock 70 kDa protein
OFODALGK_00865 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OFODALGK_00866 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OFODALGK_00867 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
OFODALGK_00868 1.7e-60 hmpT S membrane
OFODALGK_00869 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
OFODALGK_00870 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OFODALGK_00871 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OFODALGK_00872 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
OFODALGK_00873 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
OFODALGK_00874 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OFODALGK_00875 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OFODALGK_00876 2.6e-109 3.1.3.18 S IA, variant 1
OFODALGK_00877 2.2e-117 lrgB M effector of murein hydrolase
OFODALGK_00878 2.2e-58 lrgA S Effector of murein hydrolase LrgA
OFODALGK_00880 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
OFODALGK_00881 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
OFODALGK_00882 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFODALGK_00883 3.9e-104 wecD M Acetyltransferase GNAT family
OFODALGK_00884 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OFODALGK_00885 5.1e-96 GK ROK family
OFODALGK_00886 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
OFODALGK_00887 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
OFODALGK_00888 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
OFODALGK_00889 2.3e-206 potD P spermidine putrescine ABC transporter
OFODALGK_00890 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
OFODALGK_00891 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
OFODALGK_00892 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
OFODALGK_00893 7.8e-171 murB 1.3.1.98 M cell wall formation
OFODALGK_00894 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OFODALGK_00895 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OFODALGK_00896 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
OFODALGK_00897 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OFODALGK_00898 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
OFODALGK_00899 0.0 ydaO E amino acid
OFODALGK_00900 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OFODALGK_00901 4.1e-37 ylqC L Belongs to the UPF0109 family
OFODALGK_00902 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OFODALGK_00903 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
OFODALGK_00904 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
OFODALGK_00905 2.1e-74 S QueT transporter
OFODALGK_00906 1.9e-55 L Transposase
OFODALGK_00907 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OFODALGK_00908 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OFODALGK_00909 3.7e-85 ccl S cog cog4708
OFODALGK_00910 7.4e-164 rbn E Belongs to the UPF0761 family
OFODALGK_00911 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
OFODALGK_00912 3.3e-231 ytoI K transcriptional regulator containing CBS domains
OFODALGK_00913 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
OFODALGK_00914 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OFODALGK_00915 0.0 comEC S Competence protein ComEC
OFODALGK_00916 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
OFODALGK_00917 1.3e-142 plsC 2.3.1.51 I Acyltransferase
OFODALGK_00918 1.7e-77 nodB3 G polysaccharide deacetylase
OFODALGK_00919 4.1e-22 nodB3 G polysaccharide deacetylase
OFODALGK_00920 2.3e-139 yabB 2.1.1.223 L Methyltransferase
OFODALGK_00921 1e-41 yazA L endonuclease containing a URI domain
OFODALGK_00922 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OFODALGK_00923 2.3e-154 corA P CorA-like protein
OFODALGK_00924 1.9e-62 yjqA S Bacterial PH domain
OFODALGK_00925 7.8e-100 thiT S Thiamine transporter
OFODALGK_00926 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
OFODALGK_00927 1.9e-201 yjbB G Permeases of the major facilitator superfamily
OFODALGK_00928 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OFODALGK_00929 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
OFODALGK_00930 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OFODALGK_00934 1.1e-155 cjaA ET ABC transporter substrate-binding protein
OFODALGK_00935 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
OFODALGK_00936 3e-106 P ABC transporter (Permease
OFODALGK_00937 6e-115 papP P ABC transporter (Permease
OFODALGK_00938 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OFODALGK_00939 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
OFODALGK_00940 0.0 copA 3.6.3.54 P P-type ATPase
OFODALGK_00941 2.7e-73 copY K Copper transport repressor, CopY TcrY family
OFODALGK_00942 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OFODALGK_00943 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OFODALGK_00944 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
OFODALGK_00945 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OFODALGK_00946 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OFODALGK_00947 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
OFODALGK_00948 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OFODALGK_00949 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
OFODALGK_00950 3.2e-56
OFODALGK_00951 0.0 ctpE P E1-E2 ATPase
OFODALGK_00952 2e-25
OFODALGK_00953 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OFODALGK_00954 9.7e-28 L transposase activity
OFODALGK_00955 2.7e-129 K transcriptional regulator, MerR family
OFODALGK_00956 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
OFODALGK_00957 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
OFODALGK_00958 7.4e-64 XK27_02560 S cog cog2151
OFODALGK_00959 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OFODALGK_00960 7.7e-227 ytfP S Flavoprotein
OFODALGK_00962 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OFODALGK_00963 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
OFODALGK_00964 2.7e-183 ecsB U ABC transporter
OFODALGK_00965 2.3e-133 ecsA V abc transporter atp-binding protein
OFODALGK_00966 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OFODALGK_00967 5.6e-12
OFODALGK_00968 2.6e-55 S CD20-like family
OFODALGK_00969 2.1e-106
OFODALGK_00970 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
OFODALGK_00971 6.9e-206 ylbM S Belongs to the UPF0348 family
OFODALGK_00972 2e-140 yqeM Q Methyltransferase domain protein
OFODALGK_00973 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OFODALGK_00974 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OFODALGK_00975 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OFODALGK_00976 3.5e-49 yhbY J RNA-binding protein
OFODALGK_00977 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OFODALGK_00978 1.8e-98 yqeG S hydrolase of the HAD superfamily
OFODALGK_00979 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OFODALGK_00980 1.3e-57
OFODALGK_00981 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OFODALGK_00982 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OFODALGK_00983 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OFODALGK_00984 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
OFODALGK_00985 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFODALGK_00986 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFODALGK_00987 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OFODALGK_00988 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
OFODALGK_00989 6.8e-101 pncA Q isochorismatase
OFODALGK_00990 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OFODALGK_00991 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
OFODALGK_00992 2.4e-75 XK27_03180 T universal stress protein
OFODALGK_00995 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OFODALGK_00996 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
OFODALGK_00997 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
OFODALGK_00998 0.0 yjcE P NhaP-type Na H and K H antiporters
OFODALGK_01000 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
OFODALGK_01001 1.3e-184 yhcC S radical SAM protein
OFODALGK_01002 2.2e-196 ylbL T Belongs to the peptidase S16 family
OFODALGK_01003 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OFODALGK_01004 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
OFODALGK_01005 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OFODALGK_01006 1.5e-09 S Protein of unknown function (DUF4059)
OFODALGK_01007 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
OFODALGK_01008 4.7e-163 yxeN P ABC transporter (Permease
OFODALGK_01009 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
OFODALGK_01011 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFODALGK_01012 0.0 pflB 2.3.1.54 C formate acetyltransferase'
OFODALGK_01013 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
OFODALGK_01014 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFODALGK_01015 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
OFODALGK_01016 2.9e-87 D nuclear chromosome segregation
OFODALGK_01017 1.5e-127 ybbM S transport system, permease component
OFODALGK_01018 1.2e-117 ybbL S abc transporter atp-binding protein
OFODALGK_01019 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
OFODALGK_01020 4.6e-140 cppA E CppA N-terminal
OFODALGK_01021 5e-44 V CAAX protease self-immunity
OFODALGK_01022 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
OFODALGK_01023 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
OFODALGK_01026 3e-47 spiA K sequence-specific DNA binding
OFODALGK_01027 2.9e-28 blpT
OFODALGK_01028 6.7e-98 blpT
OFODALGK_01033 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
OFODALGK_01036 8.9e-133 agrA KT phosphorelay signal transduction system
OFODALGK_01037 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
OFODALGK_01039 7.3e-237 mesE M Transport protein ComB
OFODALGK_01040 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
OFODALGK_01041 0.0 mdlB V abc transporter atp-binding protein
OFODALGK_01042 0.0 mdlA V abc transporter atp-binding protein
OFODALGK_01044 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
OFODALGK_01045 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OFODALGK_01046 2.3e-72 yutD J protein conserved in bacteria
OFODALGK_01047 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OFODALGK_01049 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OFODALGK_01050 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OFODALGK_01051 0.0 ftsI 3.4.16.4 M penicillin-binding protein
OFODALGK_01052 8.1e-46 ftsL D cell division protein FtsL
OFODALGK_01053 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OFODALGK_01054 3e-128
OFODALGK_01055 9.7e-32 yhaI J Protein of unknown function (DUF805)
OFODALGK_01056 1.3e-08 D nuclear chromosome segregation
OFODALGK_01057 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OFODALGK_01058 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OFODALGK_01059 2.2e-285 XK27_00765
OFODALGK_01060 8.1e-134 ecsA_2 V abc transporter atp-binding protein
OFODALGK_01061 5.2e-125 S Protein of unknown function (DUF554)
OFODALGK_01062 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OFODALGK_01063 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OFODALGK_01064 9.8e-57 liaI S membrane
OFODALGK_01065 7e-10 XK27_02470 K LytTr DNA-binding domain protein
OFODALGK_01066 1.8e-65 KT response to antibiotic
OFODALGK_01067 5.2e-81 yebC M Membrane
OFODALGK_01068 2.9e-18 yebC M Membrane
OFODALGK_01069 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
OFODALGK_01070 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
OFODALGK_01071 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OFODALGK_01072 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OFODALGK_01073 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OFODALGK_01074 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OFODALGK_01075 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OFODALGK_01076 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OFODALGK_01078 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
OFODALGK_01079 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
OFODALGK_01080 0.0 scrA 2.7.1.211 G pts system
OFODALGK_01081 4.1e-291 scrB 3.2.1.26 GH32 G invertase
OFODALGK_01082 7.5e-180 scrR K Transcriptional
OFODALGK_01083 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OFODALGK_01084 3.4e-62 yqhY S protein conserved in bacteria
OFODALGK_01085 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OFODALGK_01086 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
OFODALGK_01087 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
OFODALGK_01089 8e-44 V 'abc transporter, ATP-binding protein
OFODALGK_01090 1e-58 V 'abc transporter, ATP-binding protein
OFODALGK_01093 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OFODALGK_01094 2e-169 corA P COG0598 Mg2 and Co2 transporters
OFODALGK_01095 3.1e-124 XK27_01040 S Pfam PF06570
OFODALGK_01097 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OFODALGK_01098 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OFODALGK_01099 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
OFODALGK_01100 2.8e-31 XK27_05745
OFODALGK_01101 2.5e-230 mutY L A G-specific adenine glycosylase
OFODALGK_01106 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFODALGK_01107 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OFODALGK_01108 1e-93 cvpA S toxin biosynthetic process
OFODALGK_01109 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OFODALGK_01110 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OFODALGK_01111 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
OFODALGK_01112 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OFODALGK_01113 2e-47 azlD E branched-chain amino acid
OFODALGK_01114 1.8e-114 azlC E AzlC protein
OFODALGK_01115 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OFODALGK_01116 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OFODALGK_01117 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
OFODALGK_01118 2.5e-33 ykzG S Belongs to the UPF0356 family
OFODALGK_01119 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OFODALGK_01120 2.7e-40 pscB M CHAP domain protein
OFODALGK_01121 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
OFODALGK_01122 8.5e-63 glnR K Transcriptional regulator
OFODALGK_01123 1.3e-87 S Fusaric acid resistance protein-like
OFODALGK_01124 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OFODALGK_01125 3.2e-42 L Transposase
OFODALGK_01126 1.9e-46 L transposase activity
OFODALGK_01127 2.5e-23 L Transposase
OFODALGK_01128 5.3e-56 L transposition
OFODALGK_01129 9.1e-83 L Integrase core domain protein
OFODALGK_01130 1e-102 L Transposase
OFODALGK_01131 2.6e-112 L Transposase
OFODALGK_01132 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OFODALGK_01133 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OFODALGK_01134 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OFODALGK_01135 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OFODALGK_01136 1.1e-142 purR 2.4.2.7 F operon repressor
OFODALGK_01137 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
OFODALGK_01138 6.9e-173 rmuC S RmuC domain protein
OFODALGK_01139 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
OFODALGK_01140 8.6e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OFODALGK_01141 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OFODALGK_01143 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OFODALGK_01144 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OFODALGK_01145 1.6e-143 tatD L Hydrolase, tatd
OFODALGK_01146 7.2e-74 yccU S CoA-binding protein
OFODALGK_01147 4.8e-51 trxA O Belongs to the thioredoxin family
OFODALGK_01148 1.9e-141 S Macro domain protein
OFODALGK_01149 2e-09 L thioesterase
OFODALGK_01150 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
OFODALGK_01153 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OFODALGK_01154 2.7e-62 L Transposase
OFODALGK_01155 1e-13 rpmH J Ribosomal protein L34
OFODALGK_01156 2e-186 jag S RNA-binding protein
OFODALGK_01157 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OFODALGK_01158 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OFODALGK_01159 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
OFODALGK_01160 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OFODALGK_01161 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OFODALGK_01162 6.7e-81 amiA E transmembrane transport
OFODALGK_01163 4.2e-74 amiA E transmembrane transport
OFODALGK_01164 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OFODALGK_01165 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OFODALGK_01166 3.5e-50 S Protein of unknown function (DUF3397)
OFODALGK_01167 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
OFODALGK_01168 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
OFODALGK_01169 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
OFODALGK_01170 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OFODALGK_01171 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
OFODALGK_01172 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
OFODALGK_01173 4.3e-77 XK27_09620 S reductase
OFODALGK_01174 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
OFODALGK_01175 1.2e-131 XK27_09615 S PAS domain
OFODALGK_01176 1.9e-07 fnt P Formate nitrite transporter
OFODALGK_01177 6.4e-54 fnt P Formate nitrite transporter
OFODALGK_01178 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
OFODALGK_01179 2.8e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OFODALGK_01180 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OFODALGK_01181 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
OFODALGK_01182 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OFODALGK_01183 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OFODALGK_01184 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OFODALGK_01185 1.6e-21 S glycolate biosynthetic process
OFODALGK_01186 1.5e-64 S phosphatase activity
OFODALGK_01187 2e-157 rrmA 2.1.1.187 Q methyltransferase
OFODALGK_01190 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OFODALGK_01191 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OFODALGK_01192 2.4e-36 yeeD O sulfur carrier activity
OFODALGK_01193 1.8e-187 yeeE S Sulphur transport
OFODALGK_01194 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OFODALGK_01195 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OFODALGK_01196 4.1e-09 S Domain of unknown function (DUF4651)
OFODALGK_01197 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OFODALGK_01198 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OFODALGK_01199 1.8e-111 S CAAX amino terminal protease family protein
OFODALGK_01201 5e-67 V CAAX protease self-immunity
OFODALGK_01202 1.4e-33 V CAAX protease self-immunity
OFODALGK_01203 8.8e-27 lanR K sequence-specific DNA binding
OFODALGK_01204 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OFODALGK_01205 7.7e-177 ytxK 2.1.1.72 L DNA methylase
OFODALGK_01206 6.8e-13 comGF U Putative Competence protein ComGF
OFODALGK_01207 4e-72 comGF U Competence protein ComGF
OFODALGK_01208 1.4e-15 NU Type II secretory pathway pseudopilin
OFODALGK_01209 1.8e-57 cglD NU Competence protein
OFODALGK_01210 8.5e-43 comGC U Required for transformation and DNA binding
OFODALGK_01211 9.2e-153 cglB NU type II secretion system
OFODALGK_01212 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OFODALGK_01213 2.9e-68 S cog cog4699
OFODALGK_01214 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFODALGK_01215 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFODALGK_01216 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFODALGK_01217 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OFODALGK_01218 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OFODALGK_01219 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
OFODALGK_01220 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
OFODALGK_01221 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OFODALGK_01222 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OFODALGK_01223 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
OFODALGK_01224 1.8e-57 asp S cog cog1302
OFODALGK_01225 3.2e-226 norN V Mate efflux family protein
OFODALGK_01226 1.9e-278 thrC 4.2.3.1 E Threonine synthase
OFODALGK_01227 1.9e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
OFODALGK_01228 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
OFODALGK_01229 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
OFODALGK_01230 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
OFODALGK_01231 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
OFODALGK_01232 0.0 pepO 3.4.24.71 O Peptidase family M13
OFODALGK_01233 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OFODALGK_01234 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OFODALGK_01235 1.3e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OFODALGK_01236 1.4e-54 treB 2.7.1.201 G PTS System
OFODALGK_01237 5.8e-21 treR K DNA-binding transcription factor activity
OFODALGK_01238 1.2e-85 treR K trehalose operon
OFODALGK_01239 3.3e-95 ywlG S Belongs to the UPF0340 family
OFODALGK_01242 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFODALGK_01243 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
OFODALGK_01248 1e-39
OFODALGK_01249 6.5e-31
OFODALGK_01250 5e-31 S Hypothetical protein (DUF2513)
OFODALGK_01251 7.7e-13
OFODALGK_01253 3.7e-216 S MvaI/BcnI restriction endonuclease family
OFODALGK_01255 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
OFODALGK_01256 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
OFODALGK_01258 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
OFODALGK_01259 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
OFODALGK_01260 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
OFODALGK_01261 3.3e-09 L PFAM Integrase, catalytic core
OFODALGK_01262 1.8e-111 L PFAM Integrase, catalytic core
OFODALGK_01263 3.3e-62 rplQ J ribosomal protein l17
OFODALGK_01264 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFODALGK_01265 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OFODALGK_01266 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OFODALGK_01267 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OFODALGK_01268 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OFODALGK_01269 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OFODALGK_01270 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OFODALGK_01271 4.4e-58 rplO J binds to the 23S rRNA
OFODALGK_01272 2.5e-23 rpmD J ribosomal protein l30
OFODALGK_01273 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OFODALGK_01274 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OFODALGK_01275 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OFODALGK_01276 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OFODALGK_01277 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OFODALGK_01278 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OFODALGK_01279 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OFODALGK_01280 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OFODALGK_01281 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OFODALGK_01282 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
OFODALGK_01283 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OFODALGK_01284 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OFODALGK_01285 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OFODALGK_01286 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OFODALGK_01287 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OFODALGK_01288 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OFODALGK_01289 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
OFODALGK_01290 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OFODALGK_01291 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
OFODALGK_01292 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OFODALGK_01293 0.0 XK27_09800 I Acyltransferase
OFODALGK_01294 1.7e-35 XK27_09805 S MORN repeat protein
OFODALGK_01295 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OFODALGK_01296 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OFODALGK_01297 1.5e-89 adk 2.7.4.3 F topology modulation protein
OFODALGK_01298 8.6e-127 Z012_04635 K sequence-specific DNA binding
OFODALGK_01300 6.3e-16 C Radical SAM
OFODALGK_01301 7.5e-191 C Radical SAM
OFODALGK_01302 3.9e-287 V ABC transporter transmembrane region
OFODALGK_01303 2.5e-89 K sequence-specific DNA binding
OFODALGK_01304 1e-36 L Replication initiation factor
OFODALGK_01305 1.4e-107 L Replication initiation factor
OFODALGK_01306 1.9e-18 S Domain of unknown function (DUF3173)
OFODALGK_01307 3.5e-216 int L Belongs to the 'phage' integrase family
OFODALGK_01309 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
OFODALGK_01310 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OFODALGK_01311 2.8e-44 yrzL S Belongs to the UPF0297 family
OFODALGK_01312 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OFODALGK_01313 4.2e-44 yrzB S Belongs to the UPF0473 family
OFODALGK_01314 6.6e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
OFODALGK_01315 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
OFODALGK_01316 7.5e-14
OFODALGK_01317 2.6e-91 XK27_10930 K acetyltransferase
OFODALGK_01318 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OFODALGK_01319 2.3e-41 yaaA S Belongs to the UPF0246 family
OFODALGK_01320 1.2e-50 yaaA S Belongs to the UPF0246 family
OFODALGK_01321 9.9e-169 XK27_01785 S cog cog1284
OFODALGK_01322 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
OFODALGK_01324 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
OFODALGK_01325 5.7e-52 metE 2.1.1.14 E Methionine synthase
OFODALGK_01326 7.6e-64 metE 2.1.1.14 E Methionine synthase
OFODALGK_01327 9.2e-36 metE 2.1.1.14 E Methionine synthase
OFODALGK_01328 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OFODALGK_01329 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OFODALGK_01331 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
OFODALGK_01332 2.7e-95 S Hydrophobic domain protein
OFODALGK_01334 3.7e-27 S Membrane
OFODALGK_01335 3.1e-101
OFODALGK_01336 1.8e-23 S Small integral membrane protein
OFODALGK_01337 1.1e-71 M Protein conserved in bacteria
OFODALGK_01338 4.9e-12 K CsbD-like
OFODALGK_01339 3.5e-97 nudL L hydrolase
OFODALGK_01340 3.4e-13 nudL L hydrolase
OFODALGK_01341 4e-19 K negative regulation of transcription, DNA-templated
OFODALGK_01342 1.7e-23 K negative regulation of transcription, DNA-templated
OFODALGK_01344 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
OFODALGK_01345 1.8e-88 S Putative adhesin
OFODALGK_01346 3.9e-161 XK27_06930 V domain protein
OFODALGK_01347 6.4e-96 XK27_06935 K transcriptional regulator
OFODALGK_01348 4.8e-55 ypaA M Membrane
OFODALGK_01349 2.7e-08
OFODALGK_01350 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OFODALGK_01351 8.2e-48 veg S Biofilm formation stimulator VEG
OFODALGK_01352 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OFODALGK_01353 3.9e-70 rplI J binds to the 23S rRNA
OFODALGK_01354 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OFODALGK_01355 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OFODALGK_01356 1.5e-77 F NUDIX domain
OFODALGK_01357 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OFODALGK_01358 0.0 S Bacterial membrane protein, YfhO
OFODALGK_01359 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
OFODALGK_01360 5.3e-85 lytE M LysM domain protein
OFODALGK_01361 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFODALGK_01362 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFODALGK_01363 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFODALGK_01364 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OFODALGK_01365 6.3e-138 ymfM S sequence-specific DNA binding
OFODALGK_01366 3.1e-242 ymfH S Peptidase M16
OFODALGK_01367 4.8e-235 ymfF S Peptidase M16
OFODALGK_01368 1.6e-45 yaaA S S4 domain protein YaaA
OFODALGK_01369 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OFODALGK_01370 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OFODALGK_01371 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OFODALGK_01372 4.2e-153 yvjA S membrane
OFODALGK_01373 6.7e-306 ybiT S abc transporter atp-binding protein
OFODALGK_01374 0.0 XK27_10405 S Bacterial membrane protein YfhO
OFODALGK_01378 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
OFODALGK_01379 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OFODALGK_01380 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
OFODALGK_01381 8.5e-134 parB K Belongs to the ParB family
OFODALGK_01382 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OFODALGK_01383 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OFODALGK_01384 1.1e-29 yyzM S Protein conserved in bacteria
OFODALGK_01385 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OFODALGK_01386 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OFODALGK_01387 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OFODALGK_01388 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OFODALGK_01389 2.7e-61 divIC D Septum formation initiator
OFODALGK_01391 8.7e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
OFODALGK_01392 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OFODALGK_01393 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OFODALGK_01394 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OFODALGK_01395 1.3e-137 L Transposase
OFODALGK_01397 1.2e-165 L integrase core domain
OFODALGK_01398 2e-52 L Transposase
OFODALGK_01399 1.6e-249 L Transposase
OFODALGK_01401 9.9e-19 S Domain of unknown function (DUF4649)
OFODALGK_01402 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OFODALGK_01403 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
OFODALGK_01404 6.5e-87
OFODALGK_01405 1.6e-77 sigH K DNA-templated transcription, initiation
OFODALGK_01406 3.5e-149 ykuT M mechanosensitive ion channel
OFODALGK_01407 7.1e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OFODALGK_01408 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OFODALGK_01409 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OFODALGK_01410 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
OFODALGK_01411 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
OFODALGK_01412 2e-177 prmA J Ribosomal protein L11 methyltransferase
OFODALGK_01413 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OFODALGK_01414 1.4e-42 F nucleotide catabolic process
OFODALGK_01415 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OFODALGK_01416 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OFODALGK_01417 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OFODALGK_01418 1.8e-83 nrdI F Belongs to the NrdI family
OFODALGK_01419 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OFODALGK_01420 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OFODALGK_01421 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
OFODALGK_01422 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
OFODALGK_01423 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
OFODALGK_01424 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
OFODALGK_01425 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OFODALGK_01426 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OFODALGK_01427 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OFODALGK_01428 6.5e-202 yhjX P Major Facilitator
OFODALGK_01429 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OFODALGK_01430 5e-94 V VanZ like family
OFODALGK_01431 1e-123 glnQ E abc transporter atp-binding protein
OFODALGK_01432 5.8e-275 glnP P ABC transporter
OFODALGK_01433 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OFODALGK_01434 1.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
OFODALGK_01435 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
OFODALGK_01436 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OFODALGK_01437 1.4e-234 sufD O assembly protein SufD
OFODALGK_01438 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OFODALGK_01439 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
OFODALGK_01440 2.2e-273 sufB O assembly protein SufB
OFODALGK_01441 7e-10 oppA E ABC transporter substrate-binding protein
OFODALGK_01442 2e-138 oppA E ABC transporter substrate-binding protein
OFODALGK_01443 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFODALGK_01444 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFODALGK_01445 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFODALGK_01446 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFODALGK_01447 3e-27 oppD P Belongs to the ABC transporter superfamily
OFODALGK_01448 2.5e-32 oppD P Belongs to the ABC transporter superfamily
OFODALGK_01449 1.2e-62 oppD P Belongs to the ABC transporter superfamily
OFODALGK_01450 3.1e-43 oppD P Belongs to the ABC transporter superfamily
OFODALGK_01451 7.5e-62 oppF P Belongs to the ABC transporter superfamily
OFODALGK_01452 4.4e-62 oppF P Belongs to the ABC transporter superfamily
OFODALGK_01453 6.4e-23
OFODALGK_01454 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OFODALGK_01455 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OFODALGK_01456 1.9e-223 EGP Major facilitator Superfamily
OFODALGK_01457 3.1e-72 adcR K transcriptional
OFODALGK_01458 2.2e-136 adcC P ABC transporter, ATP-binding protein
OFODALGK_01459 1.6e-127 adcB P ABC transporter (Permease
OFODALGK_01460 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
OFODALGK_01461 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
OFODALGK_01462 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
OFODALGK_01463 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
OFODALGK_01464 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
OFODALGK_01465 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
OFODALGK_01466 1.9e-127 yeeN K transcriptional regulatory protein
OFODALGK_01467 9.8e-50 yajC U protein transport
OFODALGK_01468 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OFODALGK_01469 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
OFODALGK_01470 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
OFODALGK_01471 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OFODALGK_01472 0.0 WQ51_06230 S ABC transporter substrate binding protein
OFODALGK_01473 5.2e-142 cmpC S abc transporter atp-binding protein
OFODALGK_01474 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OFODALGK_01475 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OFODALGK_01476 4.4e-37 L Transposase
OFODALGK_01477 6.4e-18 L transposase activity
OFODALGK_01480 4.7e-43
OFODALGK_01481 6.8e-56 S TM2 domain
OFODALGK_01482 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFODALGK_01483 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFODALGK_01484 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
OFODALGK_01485 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
OFODALGK_01486 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
OFODALGK_01487 6e-55 cof Q phosphatase activity
OFODALGK_01488 6.2e-35 cof Q phosphatase activity
OFODALGK_01489 1.6e-137 glcR K transcriptional regulator (DeoR family)
OFODALGK_01490 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFODALGK_01491 3.8e-40 K transcriptional
OFODALGK_01493 2.6e-76 S thiolester hydrolase activity
OFODALGK_01494 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
OFODALGK_01495 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OFODALGK_01496 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OFODALGK_01497 1.9e-77 yhaI L Membrane
OFODALGK_01498 5.1e-259 pepC 3.4.22.40 E aminopeptidase
OFODALGK_01499 2.5e-46 K Putative DNA-binding domain
OFODALGK_01500 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
OFODALGK_01501 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFODALGK_01502 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OFODALGK_01503 3.1e-95 ypsA S Belongs to the UPF0398 family
OFODALGK_01504 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OFODALGK_01505 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OFODALGK_01506 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
OFODALGK_01507 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
OFODALGK_01508 2.5e-23
OFODALGK_01509 7.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OFODALGK_01510 7.3e-80 XK27_09675 K -acetyltransferase
OFODALGK_01511 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OFODALGK_01512 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OFODALGK_01513 5.2e-59 L Integrase core domain protein
OFODALGK_01514 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OFODALGK_01515 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OFODALGK_01516 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OFODALGK_01517 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
OFODALGK_01518 8.8e-98 ybhL S Belongs to the BI1 family
OFODALGK_01521 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OFODALGK_01522 3.7e-91 K transcriptional regulator
OFODALGK_01523 7.6e-36 yneF S UPF0154 protein
OFODALGK_01524 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OFODALGK_01525 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OFODALGK_01526 3.5e-99 XK27_09740 S Phosphoesterase
OFODALGK_01527 7.8e-85 ykuL S CBS domain
OFODALGK_01528 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
OFODALGK_01529 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OFODALGK_01530 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OFODALGK_01531 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OFODALGK_01532 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OFODALGK_01533 1.2e-258 trkH P Cation transport protein
OFODALGK_01534 1.5e-247 trkA P Potassium transporter peripheral membrane component
OFODALGK_01535 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OFODALGK_01536 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OFODALGK_01537 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
OFODALGK_01538 5.6e-161 K sequence-specific DNA binding
OFODALGK_01539 1.2e-32 V protein secretion by the type I secretion system
OFODALGK_01540 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
OFODALGK_01541 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
OFODALGK_01542 1.6e-25 V protein secretion by the type I secretion system
OFODALGK_01543 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
OFODALGK_01544 3.7e-51 yhaI L Membrane
OFODALGK_01545 6.7e-36 S Domain of unknown function (DUF4173)
OFODALGK_01546 9.2e-132 S Domain of unknown function (DUF4173)
OFODALGK_01547 6.8e-95 ureI S AmiS/UreI family transporter
OFODALGK_01548 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OFODALGK_01549 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OFODALGK_01550 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OFODALGK_01551 6.6e-78 ureE O enzyme active site formation
OFODALGK_01552 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
OFODALGK_01553 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OFODALGK_01554 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
OFODALGK_01555 2.7e-177 cbiM P PDGLE domain
OFODALGK_01556 1.1e-136 P cobalt transport protein
OFODALGK_01557 1.6e-131 cbiO P ABC transporter
OFODALGK_01558 5.3e-153 ET amino acid transport
OFODALGK_01559 4.1e-242 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFODALGK_01560 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
OFODALGK_01561 3.8e-205 EGP Transmembrane secretion effector
OFODALGK_01562 1.8e-153 ET amino acid transport
OFODALGK_01563 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
OFODALGK_01564 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
OFODALGK_01565 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
OFODALGK_01566 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
OFODALGK_01567 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OFODALGK_01568 5.2e-98 metI P ABC transporter (Permease
OFODALGK_01569 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OFODALGK_01570 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
OFODALGK_01571 8e-94 S UPF0397 protein
OFODALGK_01572 0.0 ykoD P abc transporter atp-binding protein
OFODALGK_01573 1.2e-146 cbiQ P cobalt transport
OFODALGK_01574 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OFODALGK_01575 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
OFODALGK_01576 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
OFODALGK_01577 1.2e-244 P COG0168 Trk-type K transport systems, membrane components
OFODALGK_01578 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
OFODALGK_01579 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
OFODALGK_01580 3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFODALGK_01581 2.8e-282 T PhoQ Sensor
OFODALGK_01582 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OFODALGK_01583 6.5e-218 dnaB L Replication initiation and membrane attachment
OFODALGK_01584 4.4e-166 dnaI L Primosomal protein DnaI
OFODALGK_01585 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OFODALGK_01587 1.2e-34
OFODALGK_01588 3e-27 L Integrase core domain protein
OFODALGK_01589 3.4e-50 L transposition
OFODALGK_01590 5.7e-23 L Transposase
OFODALGK_01591 7.8e-28 L transposase activity
OFODALGK_01592 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OFODALGK_01593 4.2e-62 manO S protein conserved in bacteria
OFODALGK_01594 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
OFODALGK_01595 2.3e-116 manM G pts system
OFODALGK_01596 1.1e-181 manL 2.7.1.191 G pts system
OFODALGK_01597 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
OFODALGK_01598 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
OFODALGK_01599 1.9e-248 pbuO S permease
OFODALGK_01600 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
OFODALGK_01601 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
OFODALGK_01602 2.5e-220 brpA K Transcriptional
OFODALGK_01603 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
OFODALGK_01604 3.1e-212 nusA K Participates in both transcription termination and antitermination
OFODALGK_01605 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
OFODALGK_01606 2e-46 ylxQ J ribosomal protein
OFODALGK_01607 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OFODALGK_01608 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OFODALGK_01609 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
OFODALGK_01610 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
OFODALGK_01611 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
OFODALGK_01612 6.2e-85 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
OFODALGK_01613 3.2e-49 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
OFODALGK_01614 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OFODALGK_01615 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
OFODALGK_01616 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
OFODALGK_01617 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
OFODALGK_01618 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OFODALGK_01621 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OFODALGK_01622 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OFODALGK_01623 1.2e-74 ylbF S Belongs to the UPF0342 family
OFODALGK_01624 7.1e-46 ylbG S UPF0298 protein
OFODALGK_01625 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
OFODALGK_01626 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
OFODALGK_01627 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
OFODALGK_01628 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
OFODALGK_01629 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
OFODALGK_01630 6.8e-69 acuB S IMP dehydrogenase activity
OFODALGK_01631 8.9e-41 acuB S IMP dehydrogenase activity
OFODALGK_01632 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OFODALGK_01633 1.1e-110 yvyE 3.4.13.9 S YigZ family
OFODALGK_01634 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OFODALGK_01635 1.7e-122 comFC S Competence protein
OFODALGK_01636 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OFODALGK_01643 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
OFODALGK_01644 6.4e-108 S Domain of unknown function (DUF1803)
OFODALGK_01645 7.8e-102 ygaC J Belongs to the UPF0374 family
OFODALGK_01646 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
OFODALGK_01647 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFODALGK_01648 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
OFODALGK_01649 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
OFODALGK_01650 1.9e-115 S Haloacid dehalogenase-like hydrolase
OFODALGK_01651 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
OFODALGK_01652 4e-72 marR K Transcriptional regulator, MarR family
OFODALGK_01653 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OFODALGK_01654 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OFODALGK_01655 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
OFODALGK_01656 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
OFODALGK_01657 1.6e-126 IQ reductase
OFODALGK_01658 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OFODALGK_01659 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OFODALGK_01660 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OFODALGK_01661 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OFODALGK_01662 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OFODALGK_01663 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OFODALGK_01664 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OFODALGK_01665 1.1e-65 tnp L Transposase
OFODALGK_01666 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
OFODALGK_01667 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
OFODALGK_01668 4.7e-27 L Transposase and inactivated derivatives, TnpA family
OFODALGK_01669 3.4e-126 tnp L Transposase
OFODALGK_01671 8e-277 S Protein of unknown function (DUF3114)
OFODALGK_01672 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
OFODALGK_01673 7.7e-198 V (ABC) transporter
OFODALGK_01674 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
OFODALGK_01675 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
OFODALGK_01676 1.1e-113 K sequence-specific DNA binding
OFODALGK_01677 8.4e-155 L COG2801 Transposase and inactivated derivatives
OFODALGK_01678 6.6e-38 L transposase activity
OFODALGK_01679 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
OFODALGK_01680 1.8e-84 L Transposase
OFODALGK_01681 5.5e-122 fruR K transcriptional
OFODALGK_01682 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
OFODALGK_01683 0.0 fruA 2.7.1.202 G phosphotransferase system
OFODALGK_01684 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OFODALGK_01685 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OFODALGK_01687 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
OFODALGK_01688 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OFODALGK_01689 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
OFODALGK_01690 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
OFODALGK_01691 6.4e-29 2.3.1.128 K acetyltransferase
OFODALGK_01692 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
OFODALGK_01693 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OFODALGK_01694 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OFODALGK_01695 2.6e-64 WQ51_03320 S cog cog4835
OFODALGK_01696 9.8e-91 XK27_08360 S EDD domain protein, DegV family
OFODALGK_01697 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OFODALGK_01698 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OFODALGK_01699 0.0 yfmR S abc transporter atp-binding protein
OFODALGK_01700 1.6e-24 U response to pH
OFODALGK_01701 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
OFODALGK_01702 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
OFODALGK_01703 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
OFODALGK_01704 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
OFODALGK_01705 9.4e-77 K DNA-binding transcription factor activity
OFODALGK_01706 0.0 lmrA1 V abc transporter atp-binding protein
OFODALGK_01707 0.0 lmrA2 V abc transporter atp-binding protein
OFODALGK_01708 5.4e-45 K Acetyltransferase (GNAT) family
OFODALGK_01709 3.2e-78 sptS 2.7.13.3 T Histidine kinase
OFODALGK_01710 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OFODALGK_01711 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OFODALGK_01712 5.3e-161 cvfB S Protein conserved in bacteria
OFODALGK_01713 7.4e-35 yozE S Belongs to the UPF0346 family
OFODALGK_01714 6.7e-124 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
OFODALGK_01715 2.3e-61 rlpA M LysM domain protein
OFODALGK_01716 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
OFODALGK_01720 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OFODALGK_01721 1.8e-164 K transcriptional regulator (lysR family)
OFODALGK_01722 1.4e-186 coiA 3.6.4.12 S Competence protein
OFODALGK_01723 0.0 pepF E oligoendopeptidase F
OFODALGK_01724 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
OFODALGK_01725 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
OFODALGK_01726 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OFODALGK_01727 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
OFODALGK_01728 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
OFODALGK_01729 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
OFODALGK_01730 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OFODALGK_01731 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
OFODALGK_01732 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OFODALGK_01733 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OFODALGK_01734 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
OFODALGK_01735 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OFODALGK_01736 2.2e-130 yxkH G deacetylase
OFODALGK_01737 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
OFODALGK_01738 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OFODALGK_01739 5.5e-153 rarD S Transporter
OFODALGK_01740 2.2e-15 T peptidase
OFODALGK_01741 8.9e-14 coiA 3.6.4.12 S Competence protein
OFODALGK_01742 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OFODALGK_01743 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OFODALGK_01744 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OFODALGK_01745 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OFODALGK_01746 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
OFODALGK_01747 3.3e-78 atpF C ATP synthase F(0) sector subunit b
OFODALGK_01748 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OFODALGK_01749 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OFODALGK_01750 7.4e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OFODALGK_01751 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OFODALGK_01752 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OFODALGK_01753 2.8e-230 ftsW D Belongs to the SEDS family
OFODALGK_01754 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OFODALGK_01755 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OFODALGK_01756 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OFODALGK_01757 1.9e-161 holB 2.7.7.7 L dna polymerase iii
OFODALGK_01758 2.1e-135 yaaT S stage 0 sporulation protein
OFODALGK_01759 1.1e-34 yabA L Involved in initiation control of chromosome replication
OFODALGK_01760 3.9e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OFODALGK_01761 7.5e-233 amt P Ammonium Transporter
OFODALGK_01762 1.1e-53 glnB K Belongs to the P(II) protein family
OFODALGK_01763 4.9e-106 mur1 NU mannosyl-glycoprotein
OFODALGK_01764 1.7e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
OFODALGK_01765 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
OFODALGK_01766 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OFODALGK_01767 1.8e-53
OFODALGK_01768 7.5e-26
OFODALGK_01769 1.5e-59
OFODALGK_01770 6.1e-63 S membrane
OFODALGK_01771 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OFODALGK_01772 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OFODALGK_01773 4.5e-39 ynzC S UPF0291 protein
OFODALGK_01774 1.8e-254 cycA E permease
OFODALGK_01775 1.1e-09 uvrX 2.7.7.7 L impB/mucB/samB family
OFODALGK_01776 2.8e-24 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OFODALGK_01777 5.8e-71 pts33BCA G pts system
OFODALGK_01778 9e-96 pts33BCA G pts system
OFODALGK_01779 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
OFODALGK_01780 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OFODALGK_01785 1.4e-167 fhuR K transcriptional regulator (lysR family)
OFODALGK_01786 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OFODALGK_01787 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFODALGK_01788 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OFODALGK_01789 4.9e-227 pyrP F uracil Permease
OFODALGK_01790 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OFODALGK_01791 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
OFODALGK_01792 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
OFODALGK_01793 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
OFODALGK_01794 4e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OFODALGK_01795 1.6e-33 V permease protein
OFODALGK_01796 1e-09 V permease protein
OFODALGK_01797 8.8e-21 V permease protein
OFODALGK_01798 1.7e-07 V efflux transmembrane transporter activity
OFODALGK_01799 1.1e-24 ytrF V efflux transmembrane transporter activity
OFODALGK_01800 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OFODALGK_01801 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OFODALGK_01803 0.0 mdlB V abc transporter atp-binding protein
OFODALGK_01804 0.0 lmrA V abc transporter atp-binding protein
OFODALGK_01805 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OFODALGK_01806 5.8e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OFODALGK_01807 6.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
OFODALGK_01808 2.5e-132 rr02 KT response regulator
OFODALGK_01809 3.5e-202 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OFODALGK_01810 4.8e-168 V ABC transporter
OFODALGK_01811 5.4e-122 sagI S ABC-2 type transporter
OFODALGK_01812 4.5e-196 yceA S Belongs to the UPF0176 family
OFODALGK_01813 8e-28 XK27_00085 K Transcriptional
OFODALGK_01814 1.7e-23
OFODALGK_01815 1.2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
OFODALGK_01816 2.8e-112 S VIT family
OFODALGK_01817 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OFODALGK_01818 2.4e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OFODALGK_01819 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
OFODALGK_01820 2e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
OFODALGK_01821 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OFODALGK_01822 8.8e-104 GBS0088 J protein conserved in bacteria
OFODALGK_01823 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
OFODALGK_01824 1.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
OFODALGK_01825 1.6e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
OFODALGK_01826 7.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OFODALGK_01827 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OFODALGK_01828 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
OFODALGK_01829 2.5e-21
OFODALGK_01830 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OFODALGK_01832 3.5e-07 U protein secretion
OFODALGK_01833 2.5e-51 U protein secretion
OFODALGK_01834 7.4e-08 M Pilin isopeptide linkage domain protein
OFODALGK_01835 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
OFODALGK_01836 1.5e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
OFODALGK_01837 3.5e-49 XK27_13030
OFODALGK_01838 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OFODALGK_01839 8.3e-55 S hydrolase activity, acting on ester bonds
OFODALGK_01840 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OFODALGK_01841 6.8e-164 S Protein of unknown function (DUF3114)
OFODALGK_01842 1.2e-22 S Protein of unknown function (DUF3114)
OFODALGK_01843 1.5e-118 yqfA K protein, Hemolysin III
OFODALGK_01844 1e-25 K hmm pf08876
OFODALGK_01845 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
OFODALGK_01846 1.7e-218 mvaS 2.3.3.10 I synthase
OFODALGK_01847 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OFODALGK_01848 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OFODALGK_01849 9.7e-22
OFODALGK_01850 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OFODALGK_01851 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
OFODALGK_01852 1.5e-250 mmuP E amino acid
OFODALGK_01853 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
OFODALGK_01854 1.4e-29 S Domain of unknown function (DUF1912)
OFODALGK_01855 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
OFODALGK_01856 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OFODALGK_01857 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OFODALGK_01858 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OFODALGK_01859 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
OFODALGK_01860 4.8e-16 S Protein of unknown function (DUF2969)
OFODALGK_01863 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
OFODALGK_01866 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
OFODALGK_01867 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
OFODALGK_01868 3.7e-70 M Pfam SNARE associated Golgi protein
OFODALGK_01869 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
OFODALGK_01870 1.6e-08 S oxidoreductase
OFODALGK_01871 9.3e-59 S oxidoreductase
OFODALGK_01872 9.7e-66 S oxidoreductase
OFODALGK_01873 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
OFODALGK_01874 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
OFODALGK_01875 0.0 clpE O Belongs to the ClpA ClpB family
OFODALGK_01876 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OFODALGK_01877 1.3e-34 ykuJ S protein conserved in bacteria
OFODALGK_01878 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
OFODALGK_01879 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
OFODALGK_01880 3.1e-78 feoA P FeoA domain protein
OFODALGK_01881 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
OFODALGK_01882 1.5e-07
OFODALGK_01883 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
OFODALGK_01884 2.2e-45 K sequence-specific DNA binding
OFODALGK_01885 1.5e-35 yugF I carboxylic ester hydrolase activity
OFODALGK_01886 7.5e-23 I Alpha/beta hydrolase family
OFODALGK_01887 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OFODALGK_01888 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OFODALGK_01889 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
OFODALGK_01890 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OFODALGK_01891 5.8e-64 licT K transcriptional antiterminator
OFODALGK_01892 6.8e-53 licT K transcriptional antiterminator
OFODALGK_01893 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OFODALGK_01894 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OFODALGK_01895 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OFODALGK_01896 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OFODALGK_01897 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OFODALGK_01898 2.5e-220 mdtG EGP Major facilitator Superfamily
OFODALGK_01899 2e-33 secG U Preprotein translocase subunit SecG
OFODALGK_01900 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OFODALGK_01901 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
OFODALGK_01902 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OFODALGK_01903 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
OFODALGK_01904 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
OFODALGK_01905 4.4e-183 ccpA K Catabolite control protein A
OFODALGK_01906 2.8e-28 yyaQ S YjbR
OFODALGK_01907 6.6e-101 yyaQ V Protein conserved in bacteria
OFODALGK_01908 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OFODALGK_01909 1e-78 yueI S Protein of unknown function (DUF1694)
OFODALGK_01910 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OFODALGK_01911 2e-25 WQ51_00785
OFODALGK_01912 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OFODALGK_01913 2e-219 ywbD 2.1.1.191 J Methyltransferase
OFODALGK_01914 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OFODALGK_01915 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OFODALGK_01916 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OFODALGK_01917 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OFODALGK_01918 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OFODALGK_01919 3.2e-53 yheA S Belongs to the UPF0342 family
OFODALGK_01920 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
OFODALGK_01921 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OFODALGK_01922 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OFODALGK_01923 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
OFODALGK_01924 6.4e-252 msrR K Transcriptional regulator
OFODALGK_01925 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
OFODALGK_01926 2.4e-203 I acyl-CoA dehydrogenase
OFODALGK_01927 4.5e-97 mip S hydroperoxide reductase activity
OFODALGK_01928 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFODALGK_01929 8.9e-20
OFODALGK_01930 3.2e-46
OFODALGK_01931 1e-31 K Cro/C1-type HTH DNA-binding domain
OFODALGK_01932 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
OFODALGK_01933 9.7e-34 estA E GDSL-like Lipase/Acylhydrolase
OFODALGK_01934 1.1e-94
OFODALGK_01935 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
OFODALGK_01936 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OFODALGK_01937 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OFODALGK_01938 2.6e-194 S CRISPR-associated protein Csn2 subfamily St

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)