ORF_ID e_value Gene_name EC_number CAZy COGs Description
PKOCFEDF_00001 1.4e-42 M KxYKxGKxW signal domain protein
PKOCFEDF_00002 1.9e-101 tnpR L Resolvase, N terminal domain
PKOCFEDF_00003 5.8e-51 L transposase, IS605 OrfB family
PKOCFEDF_00004 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
PKOCFEDF_00005 2.3e-311 trxB2 1.8.1.9 C Thioredoxin domain
PKOCFEDF_00006 2.3e-104 ahpC 1.11.1.15 O Peroxiredoxin
PKOCFEDF_00007 7.2e-164 3.2.1.21 GH3 G hydrolase, family 3
PKOCFEDF_00008 1.2e-62 3.2.1.21 GH3 G hydrolase, family 3
PKOCFEDF_00009 5.4e-32 3.2.1.21 GH3 G hydrolase, family 3
PKOCFEDF_00010 2.8e-160 G Major Facilitator
PKOCFEDF_00011 7.2e-47 G Major Facilitator
PKOCFEDF_00012 1.7e-204 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
PKOCFEDF_00013 1.9e-115 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
PKOCFEDF_00014 1.6e-64 3.2.1.37 GH43 K AraC-like ligand binding domain
PKOCFEDF_00016 2.9e-295 xylB 2.7.1.12, 2.7.1.17 G Xylulose kinase
PKOCFEDF_00017 5.4e-269 xylA 5.3.1.5 G Belongs to the xylose isomerase family
PKOCFEDF_00018 6.5e-249 xylT EGP Major facilitator Superfamily
PKOCFEDF_00019 3.3e-214 xylR GK ROK family
PKOCFEDF_00020 1.7e-151 glcU U sugar transport
PKOCFEDF_00021 1.3e-250 yclK 2.7.13.3 T Histidine kinase
PKOCFEDF_00022 2.8e-131 K response regulator
PKOCFEDF_00024 3.5e-57 S Domain of unknown function (DUF956)
PKOCFEDF_00025 2.6e-169 manN G system, mannose fructose sorbose family IID component
PKOCFEDF_00026 1.7e-121 manY G PTS system
PKOCFEDF_00027 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PKOCFEDF_00028 2.9e-113 yfeX P Peroxidase
PKOCFEDF_00029 7.8e-51 yfeX P Peroxidase
PKOCFEDF_00030 2.5e-89 racA K Domain of unknown function (DUF1836)
PKOCFEDF_00031 1.5e-147 yitS S EDD domain protein, DegV family
PKOCFEDF_00032 1.7e-131 manA 5.3.1.8 G mannose-6-phosphate isomerase
PKOCFEDF_00033 4.4e-166 K LysR substrate binding domain
PKOCFEDF_00034 1e-158 MA20_14895 S Conserved hypothetical protein 698
PKOCFEDF_00035 2.2e-68 lytE M Lysin motif
PKOCFEDF_00036 9.9e-149 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
PKOCFEDF_00037 1.6e-210 oatA I Acyltransferase
PKOCFEDF_00038 3.3e-52
PKOCFEDF_00039 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PKOCFEDF_00040 5.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PKOCFEDF_00041 2.7e-115 ybbR S YbbR-like protein
PKOCFEDF_00042 3.3e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PKOCFEDF_00043 5.7e-166 murB 1.3.1.98 M Cell wall formation
PKOCFEDF_00044 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
PKOCFEDF_00045 1.8e-87 K Acetyltransferase (GNAT) domain
PKOCFEDF_00046 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PKOCFEDF_00047 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PKOCFEDF_00048 5.3e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PKOCFEDF_00049 1.4e-109 yxjI
PKOCFEDF_00050 9.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PKOCFEDF_00051 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PKOCFEDF_00052 4.5e-33 secG U Preprotein translocase
PKOCFEDF_00053 4.9e-290 clcA P chloride
PKOCFEDF_00054 2.1e-252 yifK E Amino acid permease
PKOCFEDF_00055 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PKOCFEDF_00056 6.9e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PKOCFEDF_00057 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PKOCFEDF_00058 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PKOCFEDF_00059 1e-15
PKOCFEDF_00060 1.2e-55 L Helix-turn-helix domain
PKOCFEDF_00061 4.1e-102
PKOCFEDF_00062 1.3e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PKOCFEDF_00063 8.5e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PKOCFEDF_00064 4.3e-55
PKOCFEDF_00065 9.1e-124 yrkL S Flavodoxin-like fold
PKOCFEDF_00067 5.8e-64 yeaO S Protein of unknown function, DUF488
PKOCFEDF_00068 1.2e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PKOCFEDF_00069 1.5e-203 3.1.3.1 S associated with various cellular activities
PKOCFEDF_00070 4.9e-213 S Putative metallopeptidase domain
PKOCFEDF_00071 2.5e-46
PKOCFEDF_00072 7e-229 pbuG S permease
PKOCFEDF_00073 0.0 pepO 3.4.24.71 O Peptidase family M13
PKOCFEDF_00074 2.5e-89 ymdB S Macro domain protein
PKOCFEDF_00075 1.7e-145 pnuC H nicotinamide mononucleotide transporter
PKOCFEDF_00076 1.3e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PKOCFEDF_00077 2e-169 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_00078 2e-52
PKOCFEDF_00079 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PKOCFEDF_00080 5.3e-119 tcyB U Binding-protein-dependent transport system inner membrane component
PKOCFEDF_00081 8.7e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKOCFEDF_00082 6.9e-36
PKOCFEDF_00083 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
PKOCFEDF_00084 3.1e-139 ptp3 3.1.3.48 T Tyrosine phosphatase family
PKOCFEDF_00085 3.6e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PKOCFEDF_00086 2.1e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PKOCFEDF_00087 6.5e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PKOCFEDF_00088 2.7e-180 galR K Transcriptional regulator
PKOCFEDF_00089 0.0 rafA 3.2.1.22 G alpha-galactosidase
PKOCFEDF_00090 2.1e-277 lacS G Transporter
PKOCFEDF_00091 9.1e-124 S Membrane
PKOCFEDF_00092 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PKOCFEDF_00093 0.0 pepF E oligoendopeptidase F
PKOCFEDF_00094 1.1e-176 K helix_turn _helix lactose operon repressor
PKOCFEDF_00095 3.1e-101 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_00096 1.8e-139 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PKOCFEDF_00097 1.9e-77 K AsnC family
PKOCFEDF_00098 1e-81 uspA T universal stress protein
PKOCFEDF_00099 6.6e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PKOCFEDF_00100 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PKOCFEDF_00101 6.7e-207 yeaN P Transporter, major facilitator family protein
PKOCFEDF_00102 1.9e-74 S 3-demethylubiquinone-9 3-methyltransferase
PKOCFEDF_00103 2.7e-82 nrdI F Belongs to the NrdI family
PKOCFEDF_00104 2e-250 yhdP S Transporter associated domain
PKOCFEDF_00105 3.6e-88 GM epimerase
PKOCFEDF_00106 1.3e-85 M1-874 K Domain of unknown function (DUF1836)
PKOCFEDF_00127 4.6e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PKOCFEDF_00128 3.9e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PKOCFEDF_00129 5.9e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PKOCFEDF_00130 4.8e-201 coiA 3.6.4.12 S Competence protein
PKOCFEDF_00131 1.8e-113 yjbH Q Thioredoxin
PKOCFEDF_00132 8.6e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
PKOCFEDF_00133 2.1e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PKOCFEDF_00134 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PKOCFEDF_00135 3.7e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PKOCFEDF_00136 1.1e-158 rrmA 2.1.1.187 H Methyltransferase
PKOCFEDF_00137 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PKOCFEDF_00138 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PKOCFEDF_00139 1.2e-07 S Protein of unknown function (DUF4044)
PKOCFEDF_00140 9.8e-58
PKOCFEDF_00141 5.6e-79 mraZ K Belongs to the MraZ family
PKOCFEDF_00142 3.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PKOCFEDF_00143 7e-09 ftsL D Cell division protein FtsL
PKOCFEDF_00144 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PKOCFEDF_00145 1.4e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PKOCFEDF_00146 8e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PKOCFEDF_00147 1.8e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PKOCFEDF_00148 4.3e-147 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PKOCFEDF_00149 3.5e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PKOCFEDF_00150 1.5e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PKOCFEDF_00151 7.1e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PKOCFEDF_00152 6.8e-41 yggT S YGGT family
PKOCFEDF_00153 7.8e-143 ylmH S S4 domain protein
PKOCFEDF_00154 7.2e-100 divIVA D DivIVA domain protein
PKOCFEDF_00156 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PKOCFEDF_00157 1.2e-32 cspB K Cold shock protein
PKOCFEDF_00158 3.8e-96 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PKOCFEDF_00160 1.1e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PKOCFEDF_00161 7.6e-58 XK27_04120 S Putative amino acid metabolism
PKOCFEDF_00162 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PKOCFEDF_00163 1.2e-304 S amidohydrolase
PKOCFEDF_00164 4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PKOCFEDF_00165 4.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PKOCFEDF_00166 7.1e-124 S Repeat protein
PKOCFEDF_00167 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PKOCFEDF_00168 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PKOCFEDF_00169 4.2e-74 spx4 1.20.4.1 P ArsC family
PKOCFEDF_00170 9.3e-186 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
PKOCFEDF_00171 2.2e-31 ykzG S Belongs to the UPF0356 family
PKOCFEDF_00172 3.4e-74
PKOCFEDF_00173 1.5e-77 K Winged helix DNA-binding domain
PKOCFEDF_00174 0.0 lmrA V ABC transporter, ATP-binding protein
PKOCFEDF_00175 0.0 yfiC V ABC transporter
PKOCFEDF_00176 2.4e-192 ampC V Beta-lactamase
PKOCFEDF_00177 6.4e-108 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PKOCFEDF_00178 1.8e-158 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PKOCFEDF_00179 2.8e-48
PKOCFEDF_00180 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
PKOCFEDF_00181 2.9e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PKOCFEDF_00182 3.2e-109 tdk 2.7.1.21 F thymidine kinase
PKOCFEDF_00183 1.2e-154 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PKOCFEDF_00184 1.1e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PKOCFEDF_00185 1.7e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PKOCFEDF_00186 1.1e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PKOCFEDF_00187 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PKOCFEDF_00188 8.4e-183 yibE S overlaps another CDS with the same product name
PKOCFEDF_00189 3.3e-125 yibF S overlaps another CDS with the same product name
PKOCFEDF_00190 1.6e-217 pyrP F Permease
PKOCFEDF_00191 8.4e-128 atpB C it plays a direct role in the translocation of protons across the membrane
PKOCFEDF_00192 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PKOCFEDF_00193 3.7e-53 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PKOCFEDF_00194 7.4e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PKOCFEDF_00195 2.8e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PKOCFEDF_00196 8.7e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PKOCFEDF_00197 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PKOCFEDF_00198 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PKOCFEDF_00199 3.6e-29 S Protein of unknown function (DUF1146)
PKOCFEDF_00200 8.8e-218 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
PKOCFEDF_00201 5.9e-183 mbl D Cell shape determining protein MreB Mrl
PKOCFEDF_00202 7.9e-32 S Protein of unknown function (DUF2969)
PKOCFEDF_00203 9.3e-220 rodA D Belongs to the SEDS family
PKOCFEDF_00205 4e-181 S Protein of unknown function (DUF2785)
PKOCFEDF_00206 1.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PKOCFEDF_00207 3.5e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PKOCFEDF_00208 2.3e-81 usp6 T universal stress protein
PKOCFEDF_00210 4.2e-234 rarA L recombination factor protein RarA
PKOCFEDF_00211 2.9e-84 yueI S Protein of unknown function (DUF1694)
PKOCFEDF_00212 9e-74 4.4.1.5 E Glyoxalase
PKOCFEDF_00213 5.3e-133 S Membrane
PKOCFEDF_00214 8.7e-148 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PKOCFEDF_00215 5.5e-26 S YjcQ protein
PKOCFEDF_00216 1.2e-121 srtA 3.4.22.70 M sortase family
PKOCFEDF_00217 2.3e-67 mdtG EGP Major facilitator Superfamily
PKOCFEDF_00218 9e-38 mdtG EGP Major facilitator Superfamily
PKOCFEDF_00219 6e-41 rpmE2 J Ribosomal protein L31
PKOCFEDF_00220 2.2e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PKOCFEDF_00221 2.2e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PKOCFEDF_00222 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PKOCFEDF_00223 9.3e-74 ywiB S Domain of unknown function (DUF1934)
PKOCFEDF_00224 1.8e-264 ywfO S HD domain protein
PKOCFEDF_00225 1.5e-141 yxeH S hydrolase
PKOCFEDF_00226 1.7e-30
PKOCFEDF_00227 1.3e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PKOCFEDF_00228 5.3e-203 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PKOCFEDF_00229 1.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PKOCFEDF_00230 3.2e-128 znuB U ABC 3 transport family
PKOCFEDF_00231 2.5e-92 fhuC P ABC transporter
PKOCFEDF_00232 1.9e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
PKOCFEDF_00233 2.7e-157 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PKOCFEDF_00234 1.4e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PKOCFEDF_00235 5.6e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PKOCFEDF_00236 8.4e-145 tatD L hydrolase, TatD family
PKOCFEDF_00237 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PKOCFEDF_00238 8.9e-161 yunF F Protein of unknown function DUF72
PKOCFEDF_00239 1.1e-209 norA EGP Major facilitator Superfamily
PKOCFEDF_00240 2.2e-128 cobB K SIR2 family
PKOCFEDF_00241 2.2e-187
PKOCFEDF_00242 3e-216 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PKOCFEDF_00243 2.8e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PKOCFEDF_00244 0.0 helD 3.6.4.12 L DNA helicase
PKOCFEDF_00245 5.5e-201 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PKOCFEDF_00246 8.1e-154 metQ_4 P Belongs to the nlpA lipoprotein family
PKOCFEDF_00248 4.6e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PKOCFEDF_00249 6.6e-24 phaG GT1 I carboxylic ester hydrolase activity
PKOCFEDF_00250 5.2e-90 K Transcriptional regulator
PKOCFEDF_00251 0.0 pepN 3.4.11.2 E aminopeptidase
PKOCFEDF_00252 4e-195 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PKOCFEDF_00253 4.8e-79 ctsR K Belongs to the CtsR family
PKOCFEDF_00254 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PKOCFEDF_00255 5.8e-106 K Bacterial regulatory proteins, tetR family
PKOCFEDF_00256 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKOCFEDF_00257 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKOCFEDF_00258 1.2e-134 puuD S peptidase C26
PKOCFEDF_00259 4.1e-212 ykiI
PKOCFEDF_00260 7.3e-33 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
PKOCFEDF_00261 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PKOCFEDF_00262 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PKOCFEDF_00263 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PKOCFEDF_00264 1.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PKOCFEDF_00265 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PKOCFEDF_00266 6.1e-106 rplD J Forms part of the polypeptide exit tunnel
PKOCFEDF_00267 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PKOCFEDF_00268 9.3e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PKOCFEDF_00269 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PKOCFEDF_00270 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PKOCFEDF_00271 3.5e-104 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PKOCFEDF_00272 3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PKOCFEDF_00273 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
PKOCFEDF_00274 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PKOCFEDF_00275 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PKOCFEDF_00276 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PKOCFEDF_00277 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PKOCFEDF_00278 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PKOCFEDF_00279 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PKOCFEDF_00280 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PKOCFEDF_00281 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PKOCFEDF_00282 9.7e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PKOCFEDF_00283 2.5e-23 rpmD J Ribosomal protein L30
PKOCFEDF_00284 8.1e-65 rplO J Binds to the 23S rRNA
PKOCFEDF_00285 2.6e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PKOCFEDF_00286 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PKOCFEDF_00287 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PKOCFEDF_00288 3.3e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PKOCFEDF_00289 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PKOCFEDF_00290 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PKOCFEDF_00291 4.5e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKOCFEDF_00292 2.8e-61 rplQ J Ribosomal protein L17
PKOCFEDF_00293 7.3e-147 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKOCFEDF_00294 2e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKOCFEDF_00295 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKOCFEDF_00296 4.5e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PKOCFEDF_00297 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PKOCFEDF_00298 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PKOCFEDF_00299 1e-31 S interspecies interaction between organisms
PKOCFEDF_00300 2.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PKOCFEDF_00301 2.4e-49 yktA S Belongs to the UPF0223 family
PKOCFEDF_00302 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PKOCFEDF_00303 0.0 typA T GTP-binding protein TypA
PKOCFEDF_00304 6e-211 ftsW D Belongs to the SEDS family
PKOCFEDF_00305 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PKOCFEDF_00306 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PKOCFEDF_00307 8.1e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PKOCFEDF_00308 2.5e-197 ylbL T Belongs to the peptidase S16 family
PKOCFEDF_00309 2.5e-86 comEA L Competence protein ComEA
PKOCFEDF_00310 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
PKOCFEDF_00311 0.0 comEC S Competence protein ComEC
PKOCFEDF_00312 2.7e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
PKOCFEDF_00313 1.1e-34 rpsT J Binds directly to 16S ribosomal RNA
PKOCFEDF_00314 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PKOCFEDF_00315 4.7e-154 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PKOCFEDF_00316 1.9e-65 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PKOCFEDF_00317 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PKOCFEDF_00318 3.9e-162 S Tetratricopeptide repeat
PKOCFEDF_00319 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PKOCFEDF_00320 1.8e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PKOCFEDF_00321 4.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PKOCFEDF_00322 2.3e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
PKOCFEDF_00323 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PKOCFEDF_00325 1.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKOCFEDF_00326 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PKOCFEDF_00327 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PKOCFEDF_00328 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PKOCFEDF_00329 9.5e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PKOCFEDF_00330 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PKOCFEDF_00331 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PKOCFEDF_00332 1.7e-63 S Domain of unknown function (DUF4440)
PKOCFEDF_00333 2.5e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_00334 6.2e-151 tesE Q hydratase
PKOCFEDF_00335 1.3e-40 adhR K helix_turn_helix, mercury resistance
PKOCFEDF_00336 6.3e-178 S Phosphotransferase system, EIIC
PKOCFEDF_00338 1.6e-143 S Oxidoreductase family, NAD-binding Rossmann fold
PKOCFEDF_00340 1.5e-192 nhaC C Na H antiporter NhaC
PKOCFEDF_00342 1.2e-74 ddaH 3.5.3.18 E Amidinotransferase
PKOCFEDF_00343 4.6e-88 S Aminoacyl-tRNA editing domain
PKOCFEDF_00344 2.6e-310 mco Q Multicopper oxidase
PKOCFEDF_00345 2.7e-29 ypaA S membrane
PKOCFEDF_00346 4.9e-51 K 2 iron, 2 sulfur cluster binding
PKOCFEDF_00347 9.8e-51 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PKOCFEDF_00348 3.2e-116 Q Methyltransferase domain
PKOCFEDF_00350 4.3e-101 S CAAX protease self-immunity
PKOCFEDF_00351 9.6e-94 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PKOCFEDF_00352 2.4e-135 fsr EGP Major Facilitator Superfamily
PKOCFEDF_00353 9.4e-34 K helix_turn_helix, arabinose operon control protein
PKOCFEDF_00354 7.6e-19 K helix_turn_helix, arabinose operon control protein
PKOCFEDF_00355 1.5e-100 K helix_turn_helix multiple antibiotic resistance protein
PKOCFEDF_00356 4.7e-182 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PKOCFEDF_00357 7.5e-82
PKOCFEDF_00358 2.2e-84 dps P Belongs to the Dps family
PKOCFEDF_00359 2.2e-304 ybiT S ABC transporter, ATP-binding protein
PKOCFEDF_00360 1e-33 yneR S Belongs to the HesB IscA family
PKOCFEDF_00361 7.5e-138 S NADPH-dependent FMN reductase
PKOCFEDF_00362 3.4e-288 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PKOCFEDF_00363 1.2e-160 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PKOCFEDF_00364 5.2e-104 yvdD 3.2.2.10 S Belongs to the LOG family
PKOCFEDF_00365 6.4e-63 S Domain of unknown function (DUF4828)
PKOCFEDF_00366 3.8e-190 mocA S Oxidoreductase
PKOCFEDF_00367 2.3e-235 yfmL 3.6.4.13 L DEAD DEAH box helicase
PKOCFEDF_00369 3e-75 gtcA S Teichoic acid glycosylation protein
PKOCFEDF_00370 3.2e-77 fld C Flavodoxin
PKOCFEDF_00371 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
PKOCFEDF_00372 0.0 XK27_08315 M Sulfatase
PKOCFEDF_00373 7.7e-154 yitU 3.1.3.104 S hydrolase
PKOCFEDF_00374 2e-271 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PKOCFEDF_00375 2e-91 pstS P Phosphate
PKOCFEDF_00376 2.6e-97 pstC P probably responsible for the translocation of the substrate across the membrane
PKOCFEDF_00377 1e-103 pstA P Phosphate transport system permease protein PstA
PKOCFEDF_00378 9.5e-96 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PKOCFEDF_00379 1.4e-203 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PKOCFEDF_00380 4.3e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PKOCFEDF_00381 9.1e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PKOCFEDF_00382 4.9e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PKOCFEDF_00383 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PKOCFEDF_00384 1.1e-87 ypmB S Protein conserved in bacteria
PKOCFEDF_00385 9.2e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PKOCFEDF_00386 4.7e-134 dnaD L DnaD domain protein
PKOCFEDF_00387 4.5e-119 ypuA S Protein of unknown function (DUF1002)
PKOCFEDF_00388 1.1e-192 C Aldo keto reductase family protein
PKOCFEDF_00389 8.2e-160 EG EamA-like transporter family
PKOCFEDF_00390 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PKOCFEDF_00391 5e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PKOCFEDF_00392 8.7e-110 ypsA S Belongs to the UPF0398 family
PKOCFEDF_00393 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PKOCFEDF_00394 0.0 tetP J elongation factor G
PKOCFEDF_00395 8.3e-210 S Type IV secretion-system coupling protein DNA-binding domain
PKOCFEDF_00396 8.9e-83 F Hydrolase, NUDIX family
PKOCFEDF_00397 8.5e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PKOCFEDF_00398 4.3e-194 ytjP 3.5.1.18 E Dipeptidase
PKOCFEDF_00399 5.8e-203 arcD S C4-dicarboxylate anaerobic carrier
PKOCFEDF_00400 5.8e-253 nylA 3.5.1.4 J Belongs to the amidase family
PKOCFEDF_00401 2e-26 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PKOCFEDF_00402 2.7e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
PKOCFEDF_00404 5.8e-16 D nuclear chromosome segregation
PKOCFEDF_00405 2.6e-94 treB G phosphotransferase system
PKOCFEDF_00406 1.9e-71 IQ reductase
PKOCFEDF_00407 2.4e-101 K DNA-templated transcription, initiation
PKOCFEDF_00409 0.0 N Uncharacterized conserved protein (DUF2075)
PKOCFEDF_00410 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PKOCFEDF_00411 1.1e-113 ybbL S ABC transporter, ATP-binding protein
PKOCFEDF_00412 2.7e-132 ybbM S Uncharacterised protein family (UPF0014)
PKOCFEDF_00413 1.1e-89 rmeB K transcriptional regulator, MerR family
PKOCFEDF_00414 1.2e-47 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
PKOCFEDF_00415 7.5e-87 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PKOCFEDF_00416 2.9e-33 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
PKOCFEDF_00418 4.6e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PKOCFEDF_00419 5.6e-258 guaD 3.5.4.3 F Amidohydrolase family
PKOCFEDF_00420 1.3e-221 aadAT EK Aminotransferase, class I
PKOCFEDF_00421 9.8e-26 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PKOCFEDF_00422 2e-109 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PKOCFEDF_00423 8.3e-143 ET Bacterial periplasmic substrate-binding proteins
PKOCFEDF_00425 1e-212 I transferase activity, transferring acyl groups other than amino-acyl groups
PKOCFEDF_00427 2.5e-81 padC Q Phenolic acid decarboxylase
PKOCFEDF_00428 1.2e-97 padR K Virulence activator alpha C-term
PKOCFEDF_00429 1.9e-77 ndk 2.7.4.6 F Belongs to the NDK family
PKOCFEDF_00431 1.2e-31 S SNARE associated Golgi protein
PKOCFEDF_00432 1.9e-236 N Uncharacterized conserved protein (DUF2075)
PKOCFEDF_00433 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PKOCFEDF_00435 9.6e-253 yifK E Amino acid permease
PKOCFEDF_00437 1.4e-267 pipD E Dipeptidase
PKOCFEDF_00438 1.9e-161 endA F DNA RNA non-specific endonuclease
PKOCFEDF_00439 8.5e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PKOCFEDF_00440 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PKOCFEDF_00441 4.5e-152 S Alpha/beta hydrolase of unknown function (DUF915)
PKOCFEDF_00443 2.3e-226
PKOCFEDF_00444 7.9e-191 V Beta-lactamase
PKOCFEDF_00445 1.2e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PKOCFEDF_00446 1.5e-23 S membrane transporter protein
PKOCFEDF_00447 8.9e-177 S AI-2E family transporter
PKOCFEDF_00448 5.3e-212 phbA 2.3.1.9 I Belongs to the thiolase family
PKOCFEDF_00449 3.5e-160 rssA S Phospholipase, patatin family
PKOCFEDF_00450 7e-167 K LysR substrate binding domain
PKOCFEDF_00451 0.0 1.3.5.4 C FAD binding domain
PKOCFEDF_00452 2.6e-66 S Domain of unknown function (DUF4352)
PKOCFEDF_00453 3.2e-111 yicL EG EamA-like transporter family
PKOCFEDF_00454 1.1e-62
PKOCFEDF_00455 4.5e-34
PKOCFEDF_00456 5.4e-68 S pyridoxamine 5-phosphate
PKOCFEDF_00457 4e-178 yobV1 K WYL domain
PKOCFEDF_00458 9.6e-242 XK27_08635 S UPF0210 protein
PKOCFEDF_00459 2.5e-40 gcvR T Belongs to the UPF0237 family
PKOCFEDF_00460 1.1e-167 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PKOCFEDF_00461 2.6e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PKOCFEDF_00462 3.6e-207 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PKOCFEDF_00463 3.6e-216 G Transporter, major facilitator family protein
PKOCFEDF_00464 1.2e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PKOCFEDF_00465 7.6e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PKOCFEDF_00466 4.6e-56 ydiI Q Thioesterase superfamily
PKOCFEDF_00467 1.8e-36 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
PKOCFEDF_00468 4.2e-61 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PKOCFEDF_00469 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PKOCFEDF_00470 3.4e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PKOCFEDF_00472 4e-40 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
PKOCFEDF_00473 1.3e-138 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PKOCFEDF_00474 2.3e-70 ydjP I Alpha/beta hydrolase family
PKOCFEDF_00475 2.6e-106 L Integrase
PKOCFEDF_00476 3.3e-45 K transcriptional regulator
PKOCFEDF_00478 1e-23 EGP Major Facilitator Superfamily
PKOCFEDF_00480 8.1e-69 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PKOCFEDF_00481 4.6e-73 O OsmC-like protein
PKOCFEDF_00482 1.2e-74 K Transcriptional regulator
PKOCFEDF_00483 8.9e-159 proX M ABC transporter, substrate-binding protein, QAT family
PKOCFEDF_00484 4.3e-107 proWZ P ABC transporter permease
PKOCFEDF_00485 1.9e-141 proV E ABC transporter, ATP-binding protein
PKOCFEDF_00486 9.5e-99 proW P ABC transporter, permease protein
PKOCFEDF_00487 1.1e-116 C Zinc-binding dehydrogenase
PKOCFEDF_00488 9e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
PKOCFEDF_00489 7.7e-219 4.4.1.8 E Aminotransferase, class I
PKOCFEDF_00490 1e-178 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PKOCFEDF_00491 7.1e-203 xerS L Belongs to the 'phage' integrase family
PKOCFEDF_00492 2.2e-148 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PKOCFEDF_00493 7.6e-80 hmpT S ECF-type riboflavin transporter, S component
PKOCFEDF_00494 3.1e-164 1.1.1.346 C Aldo keto reductase
PKOCFEDF_00495 3.4e-161 S DUF218 domain
PKOCFEDF_00498 1.1e-95 K Acetyltransferase (GNAT) domain
PKOCFEDF_00499 8.2e-162 I alpha/beta hydrolase fold
PKOCFEDF_00500 5.3e-71 S Phage minor capsid protein 2
PKOCFEDF_00501 9.3e-34 S Phage minor capsid protein 2
PKOCFEDF_00504 6.5e-215 2.6.1.1 E Aminotransferase
PKOCFEDF_00505 9.1e-179 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
PKOCFEDF_00506 3.5e-245 EGP Sugar (and other) transporter
PKOCFEDF_00507 9.9e-92 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
PKOCFEDF_00508 1.7e-31 S Fic/DOC family
PKOCFEDF_00509 4.1e-84 S Fic/DOC family
PKOCFEDF_00510 4.7e-68 yncA 2.3.1.79 S Maltose acetyltransferase
PKOCFEDF_00511 3.3e-88 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PKOCFEDF_00512 1.5e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PKOCFEDF_00513 1.9e-262 arcD E Amino acid permease
PKOCFEDF_00514 2.3e-53 5.1.1.13 M racemase activity, acting on amino acids and derivatives
PKOCFEDF_00515 7.1e-56 5.1.1.13 M racemase activity, acting on amino acids and derivatives
PKOCFEDF_00516 1.1e-107 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
PKOCFEDF_00517 6e-25 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
PKOCFEDF_00518 4.3e-11 clcA P chloride
PKOCFEDF_00519 1.1e-24 clcA P chloride
PKOCFEDF_00520 1.7e-24 clcA P chloride
PKOCFEDF_00521 2.5e-17 lmrB EGP Major facilitator Superfamily
PKOCFEDF_00522 4.1e-240 yhjX P Major Facilitator Superfamily
PKOCFEDF_00523 1.7e-85 S Protein of unknown function (DUF554)
PKOCFEDF_00524 1.7e-254 rarA L recombination factor protein RarA
PKOCFEDF_00526 0.0 oppD EP Psort location Cytoplasmic, score
PKOCFEDF_00527 8e-243 codA 3.5.4.1 F cytosine deaminase
PKOCFEDF_00528 6.1e-244 U Belongs to the purine-cytosine permease (2.A.39) family
PKOCFEDF_00529 6.1e-79 yebR 1.8.4.14 T GAF domain-containing protein
PKOCFEDF_00530 6.3e-93 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PKOCFEDF_00531 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PKOCFEDF_00532 2.6e-70 yqkB S Belongs to the HesB IscA family
PKOCFEDF_00533 1.6e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
PKOCFEDF_00534 1.2e-94 S Protein of unknown function (DUF1440)
PKOCFEDF_00535 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PKOCFEDF_00536 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PKOCFEDF_00537 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PKOCFEDF_00538 1.3e-170 lacX 5.1.3.3 G Aldose 1-epimerase
PKOCFEDF_00539 1.3e-151 D DNA integration
PKOCFEDF_00540 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PKOCFEDF_00541 1.2e-163 dprA LU DNA protecting protein DprA
PKOCFEDF_00542 1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PKOCFEDF_00543 6.6e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PKOCFEDF_00544 3.1e-36 yozE S Belongs to the UPF0346 family
PKOCFEDF_00545 1.6e-103 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PKOCFEDF_00546 3.4e-166 ypmR E lipolytic protein G-D-S-L family
PKOCFEDF_00547 1.5e-107 cat S Bacterial transferase hexapeptide (six repeats)
PKOCFEDF_00548 4.7e-216 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
PKOCFEDF_00549 4.4e-152 DegV S EDD domain protein, DegV family
PKOCFEDF_00550 1.7e-108 hlyIII S protein, hemolysin III
PKOCFEDF_00551 6.1e-93 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PKOCFEDF_00552 3.4e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PKOCFEDF_00553 0.0 yfmR S ABC transporter, ATP-binding protein
PKOCFEDF_00554 2.2e-221 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PKOCFEDF_00555 6.1e-157 xerD L Phage integrase, N-terminal SAM-like domain
PKOCFEDF_00556 8.5e-232 S Tetratricopeptide repeat protein
PKOCFEDF_00557 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PKOCFEDF_00558 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PKOCFEDF_00559 1.7e-208 rpsA 1.17.7.4 J Ribosomal protein S1
PKOCFEDF_00560 8.3e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PKOCFEDF_00561 4.2e-29 M Lysin motif
PKOCFEDF_00562 2.9e-276 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PKOCFEDF_00563 3e-198 ypbB 5.1.3.1 S Helix-turn-helix domain
PKOCFEDF_00564 3.7e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PKOCFEDF_00565 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PKOCFEDF_00566 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PKOCFEDF_00567 5.6e-141 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PKOCFEDF_00568 1.5e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PKOCFEDF_00569 9.6e-158 xerD D recombinase XerD
PKOCFEDF_00570 3.6e-168 cvfB S S1 domain
PKOCFEDF_00571 2.4e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PKOCFEDF_00572 0.0 dnaE 2.7.7.7 L DNA polymerase
PKOCFEDF_00574 8.9e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PKOCFEDF_00575 9.3e-155 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PKOCFEDF_00576 3.9e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
PKOCFEDF_00577 2e-118 ktrA P domain protein
PKOCFEDF_00578 1.5e-226 ktrB P Potassium uptake protein
PKOCFEDF_00579 1.3e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PKOCFEDF_00580 7.2e-217 patA 2.6.1.1 E Aminotransferase
PKOCFEDF_00581 3.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PKOCFEDF_00582 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PKOCFEDF_00583 4e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PKOCFEDF_00584 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PKOCFEDF_00585 5.9e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PKOCFEDF_00586 3.2e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
PKOCFEDF_00587 5.1e-179 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PKOCFEDF_00588 7.4e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PKOCFEDF_00589 1.2e-104 EGP Major facilitator Superfamily
PKOCFEDF_00590 1.2e-47 IQ Enoyl-(Acyl carrier protein) reductase
PKOCFEDF_00591 2.1e-44 IQ Enoyl-(Acyl carrier protein) reductase
PKOCFEDF_00592 2.6e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PKOCFEDF_00593 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PKOCFEDF_00594 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PKOCFEDF_00595 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PKOCFEDF_00596 3.5e-154 recO L Involved in DNA repair and RecF pathway recombination
PKOCFEDF_00597 4.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PKOCFEDF_00598 4.3e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PKOCFEDF_00599 1.1e-78 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PKOCFEDF_00600 4.2e-178 phoH T phosphate starvation-inducible protein PhoH
PKOCFEDF_00601 8.4e-49 yqeY S YqeY-like protein
PKOCFEDF_00602 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PKOCFEDF_00603 1.6e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
PKOCFEDF_00604 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PKOCFEDF_00605 1.9e-247 hisS 6.1.1.21 J histidyl-tRNA synthetase
PKOCFEDF_00606 2.7e-191 6.3.1.20 H Lipoate-protein ligase
PKOCFEDF_00607 2.2e-146 lytH 3.5.1.28 M Ami_3
PKOCFEDF_00608 2.2e-167 yniA G Phosphotransferase enzyme family
PKOCFEDF_00609 3.7e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PKOCFEDF_00610 2e-242 mmuP E amino acid
PKOCFEDF_00611 1.5e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PKOCFEDF_00612 4.8e-103 hom1 1.1.1.3 E Homoserine dehydrogenase
PKOCFEDF_00613 3.9e-63 hom1 1.1.1.3 E Homoserine dehydrogenase
PKOCFEDF_00615 1.5e-152 cjaA ET ABC transporter substrate-binding protein
PKOCFEDF_00616 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKOCFEDF_00617 4.8e-101 P ABC transporter permease
PKOCFEDF_00618 1.2e-112 papP P ABC transporter, permease protein
PKOCFEDF_00620 4.4e-90 yxeQ S MmgE/PrpD family
PKOCFEDF_00621 5.5e-171 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
PKOCFEDF_00622 6.6e-140 E Peptidase family M20/M25/M40
PKOCFEDF_00623 9e-79 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
PKOCFEDF_00624 2.2e-70 yxeN U ABC transporter, permease protein
PKOCFEDF_00625 5.4e-47 yxeL K acetyltransferase
PKOCFEDF_00626 1.2e-66 yxeM ET Bacterial periplasmic substrate-binding proteins
PKOCFEDF_00628 3.2e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PKOCFEDF_00629 9.5e-217 metC1 2.5.1.48, 4.4.1.8 E cystathionine
PKOCFEDF_00630 9.7e-83 slyA K Transcriptional regulator
PKOCFEDF_00631 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PKOCFEDF_00632 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PKOCFEDF_00633 6.4e-57
PKOCFEDF_00634 7e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PKOCFEDF_00635 9.8e-180 prmA J Ribosomal protein L11 methyltransferase
PKOCFEDF_00636 4e-53
PKOCFEDF_00638 1.7e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PKOCFEDF_00639 6.9e-87 S integral membrane protein
PKOCFEDF_00640 1.7e-78 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PKOCFEDF_00641 6.1e-157 argE 3.5.1.16 E Acetylornithine deacetylase
PKOCFEDF_00642 2.8e-163 P CorA-like Mg2+ transporter protein
PKOCFEDF_00643 9.7e-97 pgi 5.3.1.9 G Belongs to the GPI family
PKOCFEDF_00644 1.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PKOCFEDF_00645 1.1e-153 mepA V MATE efflux family protein
PKOCFEDF_00646 1.4e-63 mepA V MATE efflux family protein
PKOCFEDF_00647 1.6e-224 amtB P ammonium transporter
PKOCFEDF_00649 5.4e-133 XK27_08845 S ABC transporter, ATP-binding protein
PKOCFEDF_00650 6.6e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PKOCFEDF_00651 5.9e-180 ABC-SBP S ABC transporter
PKOCFEDF_00652 1.1e-289 S ABC transporter, ATP-binding protein
PKOCFEDF_00653 8.9e-206 nrnB S DHHA1 domain
PKOCFEDF_00655 5.1e-110 M ErfK YbiS YcfS YnhG
PKOCFEDF_00656 9.1e-83 nrdI F NrdI Flavodoxin like
PKOCFEDF_00657 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKOCFEDF_00658 8.8e-170 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
PKOCFEDF_00659 3.6e-182 1.17.4.1 F Ribonucleotide reductase, small chain
PKOCFEDF_00660 6e-35 S Uncharacterized protein conserved in bacteria (DUF2325)
PKOCFEDF_00661 3.5e-221 S Uncharacterized protein conserved in bacteria (DUF2325)
PKOCFEDF_00662 3.3e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PKOCFEDF_00663 3.1e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
PKOCFEDF_00664 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PKOCFEDF_00665 9.7e-205 yfnA E Amino Acid
PKOCFEDF_00666 7.2e-71 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PKOCFEDF_00667 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
PKOCFEDF_00668 8.9e-83 zur P Belongs to the Fur family
PKOCFEDF_00670 2.4e-167
PKOCFEDF_00671 1.4e-187 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PKOCFEDF_00672 9.6e-92 K Transcriptional regulator (TetR family)
PKOCFEDF_00673 6.5e-205 V domain protein
PKOCFEDF_00674 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PKOCFEDF_00675 1.5e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PKOCFEDF_00676 2.6e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PKOCFEDF_00677 0.0 asnB 6.3.5.4 E Asparagine synthase
PKOCFEDF_00678 3.3e-219 lysP E amino acid
PKOCFEDF_00679 6e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PKOCFEDF_00680 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PKOCFEDF_00681 1.1e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PKOCFEDF_00682 6.7e-140 jag S R3H domain protein
PKOCFEDF_00683 7.5e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PKOCFEDF_00684 1.9e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PKOCFEDF_00685 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PKOCFEDF_00687 1.5e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PKOCFEDF_00688 1.4e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PKOCFEDF_00689 2.2e-34 yaaA S S4 domain protein YaaA
PKOCFEDF_00690 1.2e-200 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PKOCFEDF_00691 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PKOCFEDF_00692 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PKOCFEDF_00693 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
PKOCFEDF_00694 1e-88 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PKOCFEDF_00695 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PKOCFEDF_00696 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PKOCFEDF_00697 1.2e-74 rplI J Binds to the 23S rRNA
PKOCFEDF_00698 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PKOCFEDF_00699 1.8e-207 lmrP E Major Facilitator Superfamily
PKOCFEDF_00700 9.2e-61
PKOCFEDF_00701 1.3e-192 S Psort location CytoplasmicMembrane, score
PKOCFEDF_00702 7.8e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PKOCFEDF_00703 2.1e-87 S Bacterial membrane protein, YfhO
PKOCFEDF_00704 1.5e-50 M Glycosyltransferase like family 2
PKOCFEDF_00705 1.2e-105 M Dolichyl-phosphate-mannose-protein mannosyltransferase
PKOCFEDF_00706 8.3e-168 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PKOCFEDF_00707 7.8e-64 gntR1 K Transcriptional regulator, GntR family
PKOCFEDF_00708 1.4e-156 V ABC transporter, ATP-binding protein
PKOCFEDF_00709 1.2e-14
PKOCFEDF_00711 2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
PKOCFEDF_00712 4.2e-161 EG EamA-like transporter family
PKOCFEDF_00713 1.1e-133 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PKOCFEDF_00714 2.5e-140 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PKOCFEDF_00715 1.7e-97 S Pfam:DUF3816
PKOCFEDF_00716 1.7e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PKOCFEDF_00717 1.9e-109 pncA Q Isochorismatase family
PKOCFEDF_00718 1.1e-124 3.6.1.13, 3.6.1.55 F NUDIX domain
PKOCFEDF_00719 0.0 clpE O Belongs to the ClpA ClpB family
PKOCFEDF_00721 8e-39 ptsH G phosphocarrier protein HPR
PKOCFEDF_00722 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PKOCFEDF_00723 7.9e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PKOCFEDF_00724 2.1e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
PKOCFEDF_00725 5.5e-181 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PKOCFEDF_00726 3.7e-38 ykuJ S Protein of unknown function (DUF1797)
PKOCFEDF_00727 8.3e-24 L Plasmid pRiA4b ORF-3-like protein
PKOCFEDF_00733 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PKOCFEDF_00734 1.5e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PKOCFEDF_00735 4.2e-167 whiA K May be required for sporulation
PKOCFEDF_00736 8.4e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PKOCFEDF_00737 3.2e-161 rapZ S Displays ATPase and GTPase activities
PKOCFEDF_00738 4.2e-203
PKOCFEDF_00739 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PKOCFEDF_00740 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PKOCFEDF_00742 4e-113 yfbR S HD containing hydrolase-like enzyme
PKOCFEDF_00743 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PKOCFEDF_00744 5.4e-136 cof S haloacid dehalogenase-like hydrolase
PKOCFEDF_00745 5.6e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PKOCFEDF_00746 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PKOCFEDF_00747 3.4e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PKOCFEDF_00748 5.6e-152 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PKOCFEDF_00749 9.7e-132 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PKOCFEDF_00750 3.3e-76 yphH S Cupin domain
PKOCFEDF_00751 5.8e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PKOCFEDF_00752 1.6e-224 mtnE 2.6.1.83 E Aminotransferase
PKOCFEDF_00753 9.8e-146 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PKOCFEDF_00754 1.9e-78 K FR47-like protein
PKOCFEDF_00755 2.9e-106 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PKOCFEDF_00756 3.4e-100 dps P Belongs to the Dps family
PKOCFEDF_00757 8.2e-32 copZ P Heavy-metal-associated domain
PKOCFEDF_00758 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PKOCFEDF_00759 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
PKOCFEDF_00760 2.8e-179 iunH2 3.2.2.1 F nucleoside hydrolase
PKOCFEDF_00761 2.3e-99 S ABC-type cobalt transport system, permease component
PKOCFEDF_00762 1.6e-252 cbiO1 S ABC transporter, ATP-binding protein
PKOCFEDF_00763 9.2e-113 P Cobalt transport protein
PKOCFEDF_00764 3.4e-16 yvlA
PKOCFEDF_00765 0.0 yjcE P Sodium proton antiporter
PKOCFEDF_00766 2e-191 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
PKOCFEDF_00767 9.1e-26 O OsmC-like protein
PKOCFEDF_00768 3.3e-183 D Alpha beta
PKOCFEDF_00769 8.4e-75 K Transcriptional regulator
PKOCFEDF_00770 1.4e-158
PKOCFEDF_00771 8.7e-20
PKOCFEDF_00772 2.1e-59
PKOCFEDF_00773 3.1e-75 uspA T universal stress protein
PKOCFEDF_00775 9.7e-130 qmcA O prohibitin homologues
PKOCFEDF_00776 1e-243 glpT G Major Facilitator Superfamily
PKOCFEDF_00777 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PKOCFEDF_00778 2.3e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
PKOCFEDF_00779 6.4e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PKOCFEDF_00780 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PKOCFEDF_00781 1e-243 fucP G Major Facilitator Superfamily
PKOCFEDF_00782 1.3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PKOCFEDF_00783 7.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PKOCFEDF_00784 1e-168 deoR K sugar-binding domain protein
PKOCFEDF_00785 1.8e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PKOCFEDF_00786 1.3e-198 S Domain of unknown function (DUF4432)
PKOCFEDF_00787 2.3e-173 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PKOCFEDF_00788 6.4e-260 G PTS system Galactitol-specific IIC component
PKOCFEDF_00789 2.5e-186 K helix_turn _helix lactose operon repressor
PKOCFEDF_00790 5.3e-281 yjeM E Amino Acid
PKOCFEDF_00791 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PKOCFEDF_00792 3.4e-146 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PKOCFEDF_00793 3.2e-130 gntR K UbiC transcription regulator-associated domain protein
PKOCFEDF_00794 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PKOCFEDF_00795 2.7e-129
PKOCFEDF_00796 4.6e-266 pipD E Dipeptidase
PKOCFEDF_00797 1.2e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PKOCFEDF_00798 5.9e-241 purD 6.3.4.13 F Belongs to the GARS family
PKOCFEDF_00799 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PKOCFEDF_00800 3.3e-106 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PKOCFEDF_00801 2.3e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PKOCFEDF_00802 1.4e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PKOCFEDF_00803 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKOCFEDF_00804 8e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKOCFEDF_00805 8.9e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKOCFEDF_00806 6.5e-136 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PKOCFEDF_00807 2.7e-227 S response to antibiotic
PKOCFEDF_00808 2.4e-168 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
PKOCFEDF_00809 3.3e-255 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PKOCFEDF_00810 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PKOCFEDF_00811 5.3e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PKOCFEDF_00812 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PKOCFEDF_00813 1.6e-159 K AI-2E family transporter
PKOCFEDF_00814 1.6e-08 K transcriptional regulator
PKOCFEDF_00815 9.3e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PKOCFEDF_00816 1.3e-60 ydeN S Serine hydrolase
PKOCFEDF_00817 1.1e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PKOCFEDF_00818 2.5e-87 lemA S LemA family
PKOCFEDF_00819 2.4e-156 htpX O Belongs to the peptidase M48B family
PKOCFEDF_00820 6.2e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PKOCFEDF_00821 6.6e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PKOCFEDF_00822 5.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PKOCFEDF_00823 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PKOCFEDF_00824 1.9e-56 L Toxic component of a toxin-antitoxin (TA) module
PKOCFEDF_00825 8.1e-114 S (CBS) domain
PKOCFEDF_00826 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PKOCFEDF_00827 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PKOCFEDF_00828 1.6e-39 yabO J S4 domain protein
PKOCFEDF_00829 5.6e-56 divIC D Septum formation initiator
PKOCFEDF_00830 3e-87 yabR J RNA binding
PKOCFEDF_00831 2.5e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PKOCFEDF_00832 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PKOCFEDF_00833 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PKOCFEDF_00834 7.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PKOCFEDF_00835 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PKOCFEDF_00836 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PKOCFEDF_00837 9.2e-21 L Transposase
PKOCFEDF_00838 4.2e-17 L PFAM transposase IS3 IS911 family protein
PKOCFEDF_00839 8.5e-32 L PFAM Integrase catalytic region
PKOCFEDF_00840 1.6e-47 L PFAM Integrase catalytic region
PKOCFEDF_00841 2.9e-218 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_00842 1.7e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PKOCFEDF_00843 1.6e-108 C aldo keto reductase
PKOCFEDF_00844 5.5e-107 3.1.3.73 G phosphoglycerate mutase
PKOCFEDF_00845 3.3e-09
PKOCFEDF_00846 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PKOCFEDF_00847 2.8e-199 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PKOCFEDF_00848 3.2e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PKOCFEDF_00849 9.4e-55 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PKOCFEDF_00850 1.7e-113 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PKOCFEDF_00851 1.2e-95 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PKOCFEDF_00853 3.8e-170 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PKOCFEDF_00854 0.0 dnaK O Heat shock 70 kDa protein
PKOCFEDF_00855 6.2e-60 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PKOCFEDF_00856 5.1e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PKOCFEDF_00857 5.4e-62
PKOCFEDF_00858 0.0 uvrA2 L ABC transporter
PKOCFEDF_00859 3.2e-178 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_00860 3.3e-156 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
PKOCFEDF_00861 1.1e-189 pucR QT Purine catabolism regulatory protein-like family
PKOCFEDF_00862 6.7e-68 4.2.99.20 I alpha/beta hydrolase fold
PKOCFEDF_00863 5.5e-128 pucI FH Permease for cytosine/purines, uracil, thiamine, allantoin
PKOCFEDF_00864 3.4e-226 allB 3.5.2.5 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PKOCFEDF_00865 5.5e-228 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
PKOCFEDF_00866 4.6e-127 ylbA 3.5.3.26 S protein, possibly involved in glyoxylate utilization
PKOCFEDF_00867 4.5e-202 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PKOCFEDF_00868 1.1e-242 sucD 6.2.1.5 C CoA-ligase
PKOCFEDF_00869 1.2e-217 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
PKOCFEDF_00870 2.5e-27 S Protein of unknown function (DUF2877)
PKOCFEDF_00871 1.2e-124 arcC 2.7.2.2 E Amino acid kinase family
PKOCFEDF_00872 1.9e-172 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PKOCFEDF_00873 8.2e-122 C nitroreductase
PKOCFEDF_00874 1.3e-136 E GDSL-like Lipase/Acylhydrolase family
PKOCFEDF_00875 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
PKOCFEDF_00876 3e-24 K Bacterial regulatory proteins, tetR family
PKOCFEDF_00877 2.4e-142 ET Bacterial periplasmic substrate-binding proteins
PKOCFEDF_00878 7.1e-108 XK27_05795 P ABC transporter permease
PKOCFEDF_00879 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PKOCFEDF_00880 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PKOCFEDF_00881 1.7e-159 sufD O Uncharacterized protein family (UPF0051)
PKOCFEDF_00882 5.6e-234 F Permease
PKOCFEDF_00883 3.2e-200 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PKOCFEDF_00884 1.2e-61 lytE M LysM domain protein
PKOCFEDF_00885 9e-84 ykhA 3.1.2.20 I Thioesterase superfamily
PKOCFEDF_00886 4.5e-76 hsp O Belongs to the small heat shock protein (HSP20) family
PKOCFEDF_00887 1.4e-115 K Transcriptional regulator, TetR family
PKOCFEDF_00888 1.1e-09 L Integrase
PKOCFEDF_00890 4e-22
PKOCFEDF_00891 1.7e-246 cycA E Amino acid permease
PKOCFEDF_00892 7.4e-85 perR P Belongs to the Fur family
PKOCFEDF_00893 9e-246 EGP Major facilitator Superfamily
PKOCFEDF_00894 1.7e-96 tag 3.2.2.20 L glycosylase
PKOCFEDF_00895 2.2e-51
PKOCFEDF_00896 3.3e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PKOCFEDF_00897 5.8e-138 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PKOCFEDF_00898 2.2e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PKOCFEDF_00899 1.9e-124 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
PKOCFEDF_00900 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PKOCFEDF_00901 7.1e-44
PKOCFEDF_00902 5.4e-295 ytgP S Polysaccharide biosynthesis protein
PKOCFEDF_00903 3.8e-27 3.2.1.23 S Domain of unknown function DUF302
PKOCFEDF_00904 8.3e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PKOCFEDF_00905 4.6e-271 pepV 3.5.1.18 E dipeptidase PepV
PKOCFEDF_00906 1.5e-86 uspA T Belongs to the universal stress protein A family
PKOCFEDF_00907 6.6e-254 S Putative peptidoglycan binding domain
PKOCFEDF_00908 3.1e-161 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PKOCFEDF_00909 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
PKOCFEDF_00910 1.8e-110
PKOCFEDF_00911 6.4e-182 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
PKOCFEDF_00912 4e-119 S CAAX protease self-immunity
PKOCFEDF_00913 8.4e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PKOCFEDF_00914 2.1e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PKOCFEDF_00915 3.4e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PKOCFEDF_00916 9.8e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PKOCFEDF_00917 1.8e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PKOCFEDF_00918 8.4e-199 folP 2.5.1.15 H dihydropteroate synthase
PKOCFEDF_00920 8.5e-36
PKOCFEDF_00922 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PKOCFEDF_00923 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PKOCFEDF_00924 9.8e-56 yheA S Belongs to the UPF0342 family
PKOCFEDF_00925 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PKOCFEDF_00926 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PKOCFEDF_00928 4.1e-77 hit FG histidine triad
PKOCFEDF_00929 6.8e-133 ecsA V ABC transporter, ATP-binding protein
PKOCFEDF_00930 4.3e-209 ecsB U ABC transporter
PKOCFEDF_00931 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PKOCFEDF_00932 3.6e-57 ytzB S Small secreted protein
PKOCFEDF_00933 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PKOCFEDF_00934 1.3e-116 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PKOCFEDF_00935 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PKOCFEDF_00936 1.8e-114 ybhL S Belongs to the BI1 family
PKOCFEDF_00937 2.3e-136 aroD S Serine hydrolase (FSH1)
PKOCFEDF_00938 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PKOCFEDF_00939 4.7e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PKOCFEDF_00940 2.7e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PKOCFEDF_00941 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PKOCFEDF_00942 2.6e-247 dnaB L replication initiation and membrane attachment
PKOCFEDF_00943 4.8e-171 dnaI L Primosomal protein DnaI
PKOCFEDF_00944 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PKOCFEDF_00945 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PKOCFEDF_00946 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PKOCFEDF_00947 1.6e-18 yoaK S Protein of unknown function (DUF1275)
PKOCFEDF_00948 1.4e-11 yoaK S Protein of unknown function (DUF1275)
PKOCFEDF_00949 4.6e-94 yqeG S HAD phosphatase, family IIIA
PKOCFEDF_00950 3.2e-214 yqeH S Ribosome biogenesis GTPase YqeH
PKOCFEDF_00951 2.6e-49 yhbY J RNA-binding protein
PKOCFEDF_00952 9.5e-91 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PKOCFEDF_00953 6.1e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PKOCFEDF_00954 2.3e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PKOCFEDF_00955 5.7e-135 yqeM Q Methyltransferase
PKOCFEDF_00956 1.5e-211 ylbM S Belongs to the UPF0348 family
PKOCFEDF_00957 2.7e-97 yceD S Uncharacterized ACR, COG1399
PKOCFEDF_00958 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PKOCFEDF_00959 1.6e-120 K response regulator
PKOCFEDF_00960 9e-281 arlS 2.7.13.3 T Histidine kinase
PKOCFEDF_00961 3e-232 V MatE
PKOCFEDF_00962 1.6e-67 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PKOCFEDF_00963 2.5e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PKOCFEDF_00964 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PKOCFEDF_00965 8.9e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PKOCFEDF_00966 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PKOCFEDF_00967 7.8e-60 yodB K Transcriptional regulator, HxlR family
PKOCFEDF_00968 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PKOCFEDF_00969 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PKOCFEDF_00970 1.8e-116 udk 2.7.1.48 F Cytidine monophosphokinase
PKOCFEDF_00971 4.8e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PKOCFEDF_00972 0.0 S membrane
PKOCFEDF_00973 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PKOCFEDF_00974 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PKOCFEDF_00975 1.9e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PKOCFEDF_00976 7.2e-104 gluP 3.4.21.105 S Peptidase, S54 family
PKOCFEDF_00977 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
PKOCFEDF_00978 1.7e-179 glk 2.7.1.2 G Glucokinase
PKOCFEDF_00979 1.9e-71 yqhL P Rhodanese-like protein
PKOCFEDF_00980 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
PKOCFEDF_00981 1.2e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PKOCFEDF_00982 3.2e-261 glnA 6.3.1.2 E glutamine synthetase
PKOCFEDF_00983 4.7e-13
PKOCFEDF_00984 3e-146
PKOCFEDF_00985 5.6e-175
PKOCFEDF_00986 2.5e-92 dut S Protein conserved in bacteria
PKOCFEDF_00987 3e-201 S Phage integrase family
PKOCFEDF_00988 1.4e-112 S Uncharacterised protein conserved in bacteria (DUF2326)
PKOCFEDF_00989 2.4e-16
PKOCFEDF_00991 1.1e-09 M LysM domain
PKOCFEDF_00992 1.1e-90 kcsA P Ion transport protein
PKOCFEDF_00993 2.7e-54
PKOCFEDF_00994 2.1e-67
PKOCFEDF_00995 1.2e-25 3.4.21.88 K Helix-turn-helix domain
PKOCFEDF_00996 1.4e-10 K sequence-specific DNA binding
PKOCFEDF_00997 5.4e-128 K Phage regulatory protein
PKOCFEDF_00998 3.3e-10
PKOCFEDF_01002 1e-123 S DNA metabolic process
PKOCFEDF_01003 9.7e-91 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
PKOCFEDF_01004 1.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PKOCFEDF_01005 2.5e-26 L Psort location Cytoplasmic, score
PKOCFEDF_01008 2.9e-33 arpU S Phage transcriptional regulator, ArpU family
PKOCFEDF_01010 2.4e-34
PKOCFEDF_01012 1.6e-148 S HNH endonuclease
PKOCFEDF_01013 4.8e-76 S Phage terminase, small subunit
PKOCFEDF_01014 0.0 S Phage Terminase
PKOCFEDF_01016 6.7e-237 S Phage portal protein
PKOCFEDF_01017 2.6e-69 pi136 S Caudovirus prohead serine protease
PKOCFEDF_01018 1.7e-199 S peptidase activity
PKOCFEDF_01019 4.4e-49 S Phage gp6-like head-tail connector protein
PKOCFEDF_01020 1e-30 S Phage head-tail joining protein
PKOCFEDF_01021 1.4e-36 S Bacteriophage HK97-gp10, putative tail-component
PKOCFEDF_01022 4.6e-38
PKOCFEDF_01023 1.9e-107 S Pfam:Phage_TTP_1
PKOCFEDF_01024 1.7e-12
PKOCFEDF_01025 1.3e-13
PKOCFEDF_01026 0.0 S peptidoglycan catabolic process
PKOCFEDF_01027 3e-156 S Phage tail protein
PKOCFEDF_01028 1.3e-112 S Peptidase family M23
PKOCFEDF_01029 1e-26 spoIVFA GT2,GT4 D peptidase
PKOCFEDF_01032 1.4e-30 S GDSL-like Lipase/Acylhydrolase
PKOCFEDF_01033 1.9e-49
PKOCFEDF_01035 4.7e-12
PKOCFEDF_01036 1.5e-24 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PKOCFEDF_01037 4.6e-198 S peptidoglycan catabolic process
PKOCFEDF_01038 0.0 uup S ABC transporter, ATP-binding protein
PKOCFEDF_01039 8.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PKOCFEDF_01040 1.6e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PKOCFEDF_01041 4e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PKOCFEDF_01042 0.0 ydaO E amino acid
PKOCFEDF_01043 6.4e-38
PKOCFEDF_01044 9e-113 yvyE 3.4.13.9 S YigZ family
PKOCFEDF_01045 2.5e-250 comFA L Helicase C-terminal domain protein
PKOCFEDF_01046 8e-128 comFC S Competence protein
PKOCFEDF_01047 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PKOCFEDF_01048 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PKOCFEDF_01049 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PKOCFEDF_01050 2.7e-52 KT PspC domain protein
PKOCFEDF_01051 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PKOCFEDF_01052 1.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PKOCFEDF_01053 3.6e-162 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PKOCFEDF_01054 3.4e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PKOCFEDF_01055 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PKOCFEDF_01056 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PKOCFEDF_01057 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PKOCFEDF_01058 3.8e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PKOCFEDF_01059 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
PKOCFEDF_01060 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PKOCFEDF_01061 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PKOCFEDF_01062 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PKOCFEDF_01063 1.6e-152 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PKOCFEDF_01064 1.5e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
PKOCFEDF_01065 2.5e-46 yazA L GIY-YIG catalytic domain protein
PKOCFEDF_01066 1.2e-135 yabB 2.1.1.223 L Methyltransferase small domain
PKOCFEDF_01067 4.7e-114 plsC 2.3.1.51 I Acyltransferase
PKOCFEDF_01068 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
PKOCFEDF_01069 5.4e-37 ynzC S UPF0291 protein
PKOCFEDF_01070 2.1e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PKOCFEDF_01071 2.5e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PKOCFEDF_01072 1.4e-72 L PFAM Integrase catalytic region
PKOCFEDF_01073 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PKOCFEDF_01074 4.9e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
PKOCFEDF_01075 5.6e-236 L transposase, IS605 OrfB family
PKOCFEDF_01076 2.9e-81 tlpA2 L Transposase IS200 like
PKOCFEDF_01077 2.8e-14 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PKOCFEDF_01078 1.7e-170 asnA 6.3.1.1 F aspartate--ammonia ligase
PKOCFEDF_01079 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
PKOCFEDF_01080 1.2e-94 wecD K Acetyltransferase (GNAT) family
PKOCFEDF_01081 3e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PKOCFEDF_01082 2.5e-80 S Psort location Cytoplasmic, score
PKOCFEDF_01083 9.7e-46 K helix_turn_helix, mercury resistance
PKOCFEDF_01084 4.5e-16 K helix_turn_helix, mercury resistance
PKOCFEDF_01085 1.8e-133 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
PKOCFEDF_01086 2.5e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
PKOCFEDF_01087 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PKOCFEDF_01088 4.9e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PKOCFEDF_01089 4.5e-130 ycsI S Protein of unknown function (DUF1445)
PKOCFEDF_01090 5.8e-111 ycsF S LamB/YcsF family
PKOCFEDF_01091 1.4e-183 ycsG P Natural resistance-associated macrophage protein
PKOCFEDF_01092 2.2e-249 cycA E Amino acid permease
PKOCFEDF_01093 4.9e-213 nupG F Nucleoside transporter
PKOCFEDF_01094 2.2e-144 rihC 3.2.2.1 F Nucleoside
PKOCFEDF_01095 9e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PKOCFEDF_01096 8.7e-157 noc K Belongs to the ParB family
PKOCFEDF_01097 4.1e-142 spo0J K Belongs to the ParB family
PKOCFEDF_01098 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
PKOCFEDF_01099 1.7e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PKOCFEDF_01100 2.9e-134 XK27_01040 S Protein of unknown function (DUF1129)
PKOCFEDF_01101 3.8e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PKOCFEDF_01102 1.4e-160 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PKOCFEDF_01103 5.2e-131 epsB M biosynthesis protein
PKOCFEDF_01104 2.1e-113 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PKOCFEDF_01105 2e-138 ywqE 3.1.3.48 GM PHP domain protein
PKOCFEDF_01106 2.3e-92 capM M Bacterial sugar transferase
PKOCFEDF_01107 1.3e-90 lsgF M Glycosyl transferase family 2
PKOCFEDF_01108 1e-10 S Polysaccharide pyruvyl transferase
PKOCFEDF_01109 1.1e-17 S interspecies interaction between organisms
PKOCFEDF_01110 1.2e-138 IQ reductase
PKOCFEDF_01111 9.9e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
PKOCFEDF_01112 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PKOCFEDF_01113 3.4e-219 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PKOCFEDF_01114 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PKOCFEDF_01115 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PKOCFEDF_01116 3.5e-165 camS S sex pheromone
PKOCFEDF_01117 6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PKOCFEDF_01118 6.7e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PKOCFEDF_01119 1.1e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PKOCFEDF_01120 2.1e-185 yegS 2.7.1.107 G Lipid kinase
PKOCFEDF_01121 5e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PKOCFEDF_01122 2.2e-50 K TRANSCRIPTIONal
PKOCFEDF_01123 1.1e-206 XK27_08315 M Sulfatase
PKOCFEDF_01124 7.8e-139 yihY S Belongs to the UPF0761 family
PKOCFEDF_01125 7.1e-30 S Protein of unknown function (DUF2922)
PKOCFEDF_01126 2.1e-07
PKOCFEDF_01127 1.8e-142 recX 2.4.1.337 GT4 S Regulatory protein RecX
PKOCFEDF_01128 4.2e-118 rfbP M Bacterial sugar transferase
PKOCFEDF_01129 1.4e-144 cps1D M Domain of unknown function (DUF4422)
PKOCFEDF_01130 2.4e-33 M biosynthesis protein
PKOCFEDF_01131 1.5e-67 M Domain of unknown function (DUF4422)
PKOCFEDF_01132 1.4e-74 cps3F
PKOCFEDF_01133 3e-86 M transferase activity, transferring glycosyl groups
PKOCFEDF_01134 1.1e-76 M Core-2/I-Branching enzyme
PKOCFEDF_01135 6.2e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
PKOCFEDF_01136 6.7e-217 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PKOCFEDF_01137 9.2e-75 waaB GT4 M Glycosyl transferases group 1
PKOCFEDF_01138 1.7e-65 S enterobacterial common antigen metabolic process
PKOCFEDF_01139 2.1e-53 acmD M repeat protein
PKOCFEDF_01140 9.5e-26
PKOCFEDF_01141 3e-21 scrR K Transcriptional regulator, LacI family
PKOCFEDF_01142 6.4e-134 scrR K Transcriptional regulator, LacI family
PKOCFEDF_01143 2.9e-168 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PKOCFEDF_01144 2.6e-46 czrA K Transcriptional regulator, ArsR family
PKOCFEDF_01145 1.8e-75 argR K Regulates arginine biosynthesis genes
PKOCFEDF_01146 5.5e-124 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PKOCFEDF_01147 6.6e-158 hrtB V ABC transporter permease
PKOCFEDF_01148 1.5e-106 ygfC K Bacterial regulatory proteins, tetR family
PKOCFEDF_01149 9.3e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
PKOCFEDF_01150 2.7e-280 mntH P H( )-stimulated, divalent metal cation uptake system
PKOCFEDF_01151 2.1e-20
PKOCFEDF_01152 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PKOCFEDF_01153 1.2e-69 L nuclease
PKOCFEDF_01154 3.8e-162 F DNA/RNA non-specific endonuclease
PKOCFEDF_01155 6.3e-189 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PKOCFEDF_01156 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
PKOCFEDF_01157 2.4e-214 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PKOCFEDF_01158 2.3e-67 psiE S Phosphate-starvation-inducible E
PKOCFEDF_01159 1.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PKOCFEDF_01160 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PKOCFEDF_01161 4.2e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PKOCFEDF_01162 2.1e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PKOCFEDF_01163 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PKOCFEDF_01164 1.1e-90 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
PKOCFEDF_01165 3.7e-59 2.1.1.72, 3.1.21.4 L restriction endonuclease
PKOCFEDF_01166 1.2e-84 ysdA CP transmembrane transport
PKOCFEDF_01167 2e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PKOCFEDF_01168 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PKOCFEDF_01169 3e-251 malT G Major Facilitator
PKOCFEDF_01170 8.3e-176 malR K Transcriptional regulator, LacI family
PKOCFEDF_01171 5.7e-71 K Transcriptional regulator
PKOCFEDF_01172 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PKOCFEDF_01173 3.6e-206 htrA 3.4.21.107 O serine protease
PKOCFEDF_01174 8.7e-153 vicX 3.1.26.11 S domain protein
PKOCFEDF_01175 1.8e-142 yycI S YycH protein
PKOCFEDF_01176 1.7e-235 yycH S YycH protein
PKOCFEDF_01177 0.0 vicK 2.7.13.3 T Histidine kinase
PKOCFEDF_01178 6.8e-130 K response regulator
PKOCFEDF_01181 8.9e-116 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PKOCFEDF_01182 2.4e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
PKOCFEDF_01183 4e-264 pepC 3.4.22.40 E Peptidase C1-like family
PKOCFEDF_01184 9.6e-166 I alpha/beta hydrolase fold
PKOCFEDF_01185 6.1e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PKOCFEDF_01186 5.5e-167 mleP2 S Sodium Bile acid symporter family
PKOCFEDF_01187 9.8e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PKOCFEDF_01188 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PKOCFEDF_01190 2.6e-64 ydcK S Belongs to the SprT family
PKOCFEDF_01191 0.0 yhgF K Tex-like protein N-terminal domain protein
PKOCFEDF_01192 2.6e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PKOCFEDF_01193 8.5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PKOCFEDF_01194 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
PKOCFEDF_01195 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PKOCFEDF_01196 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PKOCFEDF_01197 4.9e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PKOCFEDF_01198 6.6e-104 wecD3 K Acetyltransferase (GNAT) family
PKOCFEDF_01199 1.3e-307 ubiB S ABC1 family
PKOCFEDF_01200 2.2e-128 1.14.12.17 C Oxidoreductase NAD-binding domain
PKOCFEDF_01201 8.8e-170 GK ROK family
PKOCFEDF_01202 1.3e-39
PKOCFEDF_01203 4.7e-79 copY K Copper transport repressor CopY TcrY
PKOCFEDF_01205 8.3e-85 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
PKOCFEDF_01207 1.9e-172 mutR K Transcriptional activator, Rgg GadR MutR family
PKOCFEDF_01208 2.9e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PKOCFEDF_01209 4.2e-229 gntT EG Gluconate
PKOCFEDF_01210 1.4e-181 K Transcriptional regulator, LacI family
PKOCFEDF_01211 2.8e-60 yneR
PKOCFEDF_01212 2.4e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PKOCFEDF_01213 1.4e-95 V VanZ like family
PKOCFEDF_01214 9e-265 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PKOCFEDF_01215 3e-68 ydgH S MMPL family
PKOCFEDF_01216 2.5e-33
PKOCFEDF_01217 2e-166 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
PKOCFEDF_01219 1e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PKOCFEDF_01220 1.4e-159 hipB K Helix-turn-helix
PKOCFEDF_01221 1.5e-58 yitW S Iron-sulfur cluster assembly protein
PKOCFEDF_01222 3.5e-186 narK P Major Facilitator Superfamily
PKOCFEDF_01223 5.8e-40 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PKOCFEDF_01224 4.5e-92 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PKOCFEDF_01225 1.5e-143 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
PKOCFEDF_01226 1.9e-228 ndh 1.6.99.3 C NADH dehydrogenase
PKOCFEDF_01227 7.3e-176 fecB P Periplasmic binding protein
PKOCFEDF_01228 7.2e-272 sufB O assembly protein SufB
PKOCFEDF_01229 1.2e-82 nifU C SUF system FeS assembly protein, NifU family
PKOCFEDF_01230 1.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PKOCFEDF_01231 1.4e-237 sufD O FeS assembly protein SufD
PKOCFEDF_01232 9.4e-144 sufC O FeS assembly ATPase SufC
PKOCFEDF_01233 1.4e-33 feoA P FeoA domain
PKOCFEDF_01234 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PKOCFEDF_01235 6.7e-23 S Virus attachment protein p12 family
PKOCFEDF_01236 5.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PKOCFEDF_01237 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PKOCFEDF_01238 2.2e-182 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_01239 4.3e-214 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
PKOCFEDF_01240 1.3e-88 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PKOCFEDF_01241 9.5e-23 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PKOCFEDF_01242 2.7e-139 dtpT U amino acid peptide transporter
PKOCFEDF_01243 1.2e-73 dtpT U amino acid peptide transporter
PKOCFEDF_01244 2.2e-11 dtpT U amino acid peptide transporter
PKOCFEDF_01246 1.9e-152 S Sucrose-6F-phosphate phosphohydrolase
PKOCFEDF_01247 2e-155 1.6.5.2 GM NAD(P)H-binding
PKOCFEDF_01248 2.1e-157 S Alpha beta hydrolase
PKOCFEDF_01249 5.9e-237 lmrB EGP Major facilitator Superfamily
PKOCFEDF_01251 0.0 S Bacterial membrane protein YfhO
PKOCFEDF_01252 8.6e-12
PKOCFEDF_01253 1.7e-48
PKOCFEDF_01254 0.0 kup P Transport of potassium into the cell
PKOCFEDF_01256 1.1e-281 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PKOCFEDF_01257 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PKOCFEDF_01258 0.0 yjbQ P TrkA C-terminal domain protein
PKOCFEDF_01259 1.8e-275 pipD E Dipeptidase
PKOCFEDF_01260 1.9e-145 S Alpha/beta hydrolase of unknown function (DUF915)
PKOCFEDF_01261 6.1e-233 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKOCFEDF_01262 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PKOCFEDF_01263 5e-167 T Calcineurin-like phosphoesterase superfamily domain
PKOCFEDF_01264 4.3e-160 EGP Major facilitator Superfamily
PKOCFEDF_01265 1.1e-199 mdtG EGP Major facilitator Superfamily
PKOCFEDF_01266 5.8e-250 yhdP S Transporter associated domain
PKOCFEDF_01267 1.6e-214 naiP EGP Major facilitator Superfamily
PKOCFEDF_01268 6.6e-23 K LysR substrate binding domain protein
PKOCFEDF_01269 1.4e-65 K LysR substrate binding domain protein
PKOCFEDF_01270 4.8e-210 E GDSL-like Lipase/Acylhydrolase family
PKOCFEDF_01271 2.3e-195 lplA 6.3.1.20 H Lipoate-protein ligase
PKOCFEDF_01272 4.5e-258 lpdA 1.8.1.4 C Dehydrogenase
PKOCFEDF_01273 2.2e-198 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PKOCFEDF_01274 5.8e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PKOCFEDF_01275 5.3e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PKOCFEDF_01276 4.7e-31 yphJ 4.1.1.44 S decarboxylase
PKOCFEDF_01277 2e-43 azlD E Branched-chain amino acid transport
PKOCFEDF_01278 7.4e-46 azlC E azaleucine resistance protein AzlC
PKOCFEDF_01279 1e-284 thrC 4.2.3.1 E Threonine synthase
PKOCFEDF_01280 7.8e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PKOCFEDF_01281 8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PKOCFEDF_01282 3.5e-99 K Acetyltransferase (GNAT) domain
PKOCFEDF_01283 5.3e-113 ylbE GM NAD(P)H-binding
PKOCFEDF_01284 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PKOCFEDF_01285 1.4e-133 S Belongs to the UPF0246 family
PKOCFEDF_01286 1.3e-84
PKOCFEDF_01287 3.2e-161 degV S EDD domain protein, DegV family
PKOCFEDF_01288 0.0 FbpA K Fibronectin-binding protein
PKOCFEDF_01289 2.4e-98 ywrO S Flavodoxin-like fold
PKOCFEDF_01290 2.5e-43 S Protein conserved in bacteria
PKOCFEDF_01291 3e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PKOCFEDF_01292 2.1e-51 S Sugar efflux transporter for intercellular exchange
PKOCFEDF_01293 3.8e-17 xre K Helix-turn-helix domain
PKOCFEDF_01294 1.8e-198 gldA 1.1.1.6 C dehydrogenase
PKOCFEDF_01296 8.6e-188 EGP Major facilitator Superfamily
PKOCFEDF_01298 0.0 asnB 6.3.5.4 E Aluminium induced protein
PKOCFEDF_01299 6.1e-18 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PKOCFEDF_01300 7.3e-13
PKOCFEDF_01301 5.2e-31 scrR3 K Transcriptional regulator, LacI family
PKOCFEDF_01302 4.7e-121 scrR3 K Transcriptional regulator, LacI family
PKOCFEDF_01303 1.3e-78 F Nucleoside 2-deoxyribosyltransferase
PKOCFEDF_01304 6.5e-84
PKOCFEDF_01306 9.6e-262 yjeM E Amino Acid
PKOCFEDF_01307 7.1e-139 ponA V Beta-lactamase enzyme family
PKOCFEDF_01308 4.2e-223 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PKOCFEDF_01309 4.4e-92
PKOCFEDF_01310 2.8e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PKOCFEDF_01311 1e-107 lssY 3.6.1.27 I Acid phosphatase homologues
PKOCFEDF_01312 1.6e-54 S MazG-like family
PKOCFEDF_01313 0.0 L Helicase C-terminal domain protein
PKOCFEDF_01314 1e-69 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
PKOCFEDF_01315 4.7e-94 K transcriptional regulator
PKOCFEDF_01316 3.2e-134 lmrB EGP Major facilitator Superfamily
PKOCFEDF_01317 2.5e-116 yecS E ABC transporter permease
PKOCFEDF_01318 1.5e-155 yckB ET Belongs to the bacterial solute-binding protein 3 family
PKOCFEDF_01319 5.7e-109 XK27_02070 S Nitroreductase family
PKOCFEDF_01320 4.5e-70 rnhA 3.1.26.4 L Ribonuclease HI
PKOCFEDF_01321 1.7e-70 esbA S Family of unknown function (DUF5322)
PKOCFEDF_01322 2.8e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PKOCFEDF_01323 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PKOCFEDF_01324 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
PKOCFEDF_01325 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PKOCFEDF_01326 3.8e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
PKOCFEDF_01327 3.5e-163 K Bacterial regulatory helix-turn-helix protein, lysR family
PKOCFEDF_01328 1.4e-65 S Enoyl-(Acyl carrier protein) reductase
PKOCFEDF_01330 9.2e-55 S Alpha/beta hydrolase family
PKOCFEDF_01331 3.1e-10 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PKOCFEDF_01332 7.9e-66 K Bacterial regulatory helix-turn-helix protein, lysR family
PKOCFEDF_01334 9.1e-20 C Aldo keto reductase
PKOCFEDF_01335 3.4e-30 C Aldo keto reductase
PKOCFEDF_01338 4e-25 C Aldo/keto reductase family
PKOCFEDF_01339 7.8e-35
PKOCFEDF_01340 5.4e-259 isdH M Iron Transport-associated domain
PKOCFEDF_01341 1e-94 M Iron Transport-associated domain
PKOCFEDF_01342 2.8e-149 isdE P Periplasmic binding protein
PKOCFEDF_01343 1.1e-151 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PKOCFEDF_01344 5.4e-141 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
PKOCFEDF_01345 2e-219 iscS 2.8.1.7 E Aminotransferase class V
PKOCFEDF_01346 4.2e-53 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PKOCFEDF_01347 2.3e-78 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PKOCFEDF_01348 2e-101 P Cadmium resistance transporter
PKOCFEDF_01349 9.2e-116 S Protein of unknown function (DUF554)
PKOCFEDF_01350 3.2e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PKOCFEDF_01351 1e-156 P Belongs to the nlpA lipoprotein family
PKOCFEDF_01352 2.5e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PKOCFEDF_01353 6.1e-162 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PKOCFEDF_01354 2e-70 K LysR substrate binding domain
PKOCFEDF_01355 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PKOCFEDF_01356 2.5e-126 pgm3 G phosphoglycerate mutase family
PKOCFEDF_01357 8.8e-148 qorB 1.6.5.2 GM NmrA-like family
PKOCFEDF_01358 3.5e-228 pbuX F xanthine permease
PKOCFEDF_01359 4.4e-169 corA P CorA-like Mg2+ transporter protein
PKOCFEDF_01360 2.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PKOCFEDF_01361 5.2e-142 terC P membrane
PKOCFEDF_01362 1e-56 trxA1 O Belongs to the thioredoxin family
PKOCFEDF_01363 9.2e-59 EGP Major facilitator Superfamily
PKOCFEDF_01364 3.8e-169 EGP Major facilitator Superfamily
PKOCFEDF_01365 4.7e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PKOCFEDF_01366 1.5e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PKOCFEDF_01367 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PKOCFEDF_01368 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PKOCFEDF_01369 9.3e-50 ylxQ J ribosomal protein
PKOCFEDF_01370 1.4e-47 ylxR K Protein of unknown function (DUF448)
PKOCFEDF_01371 1.8e-223 nusA K Participates in both transcription termination and antitermination
PKOCFEDF_01372 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
PKOCFEDF_01373 9.6e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PKOCFEDF_01374 8.1e-114
PKOCFEDF_01377 8.7e-164 yjjH S Calcineurin-like phosphoesterase
PKOCFEDF_01378 3.4e-256 dtpT U amino acid peptide transporter
PKOCFEDF_01379 3.1e-152 D nuclear chromosome segregation
PKOCFEDF_01381 2.5e-14
PKOCFEDF_01382 2.5e-43 relB L Addiction module antitoxin, RelB DinJ family
PKOCFEDF_01383 7.9e-165 repA S Replication initiator protein A
PKOCFEDF_01384 5.4e-147 soj D CobQ CobB MinD ParA nucleotide binding domain protein
PKOCFEDF_01385 6.7e-51 S Family of unknown function (DUF5388)
PKOCFEDF_01387 4.5e-58 M repeat protein
PKOCFEDF_01388 1.1e-08
PKOCFEDF_01389 3.8e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PKOCFEDF_01390 2.7e-141 yueF S AI-2E family transporter
PKOCFEDF_01391 5e-38 S Psort location CytoplasmicMembrane, score
PKOCFEDF_01392 1.4e-165 ykoT GT2 M Glycosyl transferase family 2
PKOCFEDF_01393 3e-100 dedA S SNARE-like domain protein
PKOCFEDF_01394 9.8e-25 S Protein of unknown function (DUF1461)
PKOCFEDF_01395 7.3e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PKOCFEDF_01396 1.2e-97 yutD S Protein of unknown function (DUF1027)
PKOCFEDF_01397 5.3e-110 S Calcineurin-like phosphoesterase
PKOCFEDF_01398 2.3e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PKOCFEDF_01399 1.5e-158 ytxK 2.1.1.72 L N-6 DNA Methylase
PKOCFEDF_01401 1.3e-14
PKOCFEDF_01403 1e-15 NU general secretion pathway protein
PKOCFEDF_01404 1.1e-47 comGC U competence protein ComGC
PKOCFEDF_01405 1.7e-158 comGB NU type II secretion system
PKOCFEDF_01406 2.7e-177 comGA NU Type II IV secretion system protein
PKOCFEDF_01407 5.7e-173 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
PKOCFEDF_01408 1.9e-102 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
PKOCFEDF_01409 1.1e-80 mltD CBM50 M PFAM NLP P60 protein
PKOCFEDF_01410 3.7e-134 yebC K Transcriptional regulatory protein
PKOCFEDF_01411 5.8e-83
PKOCFEDF_01412 1.1e-184 ccpA K catabolite control protein A
PKOCFEDF_01413 1e-212 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PKOCFEDF_01414 4.9e-70
PKOCFEDF_01415 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PKOCFEDF_01416 1.8e-156 ykuT M mechanosensitive ion channel
PKOCFEDF_01417 9.3e-150 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PKOCFEDF_01418 2.6e-94 S Phosphoesterase
PKOCFEDF_01419 1.1e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PKOCFEDF_01420 6.3e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PKOCFEDF_01421 3.3e-92 yslB S Protein of unknown function (DUF2507)
PKOCFEDF_01422 1.7e-224 clcA_2 P Chloride transporter, ClC family
PKOCFEDF_01423 1e-53 trxA O Belongs to the thioredoxin family
PKOCFEDF_01424 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PKOCFEDF_01425 1.4e-90 cvpA S Colicin V production protein
PKOCFEDF_01426 4.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PKOCFEDF_01427 5.7e-33 yrzB S Belongs to the UPF0473 family
PKOCFEDF_01428 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PKOCFEDF_01429 1.2e-42 yrzL S Belongs to the UPF0297 family
PKOCFEDF_01430 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PKOCFEDF_01431 3.5e-231 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PKOCFEDF_01432 1.8e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PKOCFEDF_01433 2.7e-41 yajC U Preprotein translocase
PKOCFEDF_01434 2.4e-175 2.4.2.29 F queuine tRNA-ribosyltransferase activity
PKOCFEDF_01435 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PKOCFEDF_01436 1.1e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PKOCFEDF_01437 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PKOCFEDF_01438 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PKOCFEDF_01439 1.5e-198 rny S Endoribonuclease that initiates mRNA decay
PKOCFEDF_01440 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PKOCFEDF_01441 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
PKOCFEDF_01442 6.7e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PKOCFEDF_01443 1.8e-96 ymfM S Helix-turn-helix domain
PKOCFEDF_01444 5.8e-252 ymfH S Peptidase M16
PKOCFEDF_01445 1.5e-231 ymfF S Peptidase M16 inactive domain protein
PKOCFEDF_01446 1.7e-159 aatB ET ABC transporter substrate-binding protein
PKOCFEDF_01447 7.4e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKOCFEDF_01448 3e-108 glnP P ABC transporter permease
PKOCFEDF_01449 6.6e-93 mreD M rod shape-determining protein MreD
PKOCFEDF_01450 3.7e-146 mreC M Involved in formation and maintenance of cell shape
PKOCFEDF_01451 1.9e-181 mreB D cell shape determining protein MreB
PKOCFEDF_01452 2.5e-115 radC L DNA repair protein
PKOCFEDF_01453 1.4e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PKOCFEDF_01454 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PKOCFEDF_01455 7.7e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PKOCFEDF_01456 1.2e-06
PKOCFEDF_01458 2.2e-16
PKOCFEDF_01459 4.4e-39
PKOCFEDF_01460 1.9e-11 M LysM domain
PKOCFEDF_01461 3.6e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PKOCFEDF_01462 6.5e-211 EG GntP family permease
PKOCFEDF_01463 3.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PKOCFEDF_01464 2.1e-213 iscS2 2.8.1.7 E Aminotransferase class V
PKOCFEDF_01465 1.3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PKOCFEDF_01466 1.4e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PKOCFEDF_01469 1.9e-121 K Crp-like helix-turn-helix domain
PKOCFEDF_01470 5.2e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
PKOCFEDF_01471 1.9e-130 cpmA S AIR carboxylase
PKOCFEDF_01472 1.7e-214 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PKOCFEDF_01473 3.8e-128 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PKOCFEDF_01474 6.5e-148 larE S NAD synthase
PKOCFEDF_01475 3.4e-183 hoxN U High-affinity nickel-transport protein
PKOCFEDF_01476 7.4e-97 pgi 5.3.1.9 G Belongs to the GPI family
PKOCFEDF_01478 3.5e-85 K GNAT family
PKOCFEDF_01479 1.9e-119 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PKOCFEDF_01480 9e-161 ytbE 1.1.1.346 S Aldo keto reductase
PKOCFEDF_01481 4.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PKOCFEDF_01482 3.6e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PKOCFEDF_01484 1e-56
PKOCFEDF_01486 3.9e-07
PKOCFEDF_01487 5.4e-253 G Major Facilitator
PKOCFEDF_01488 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
PKOCFEDF_01489 9.7e-175 K Transcriptional regulator, LacI family
PKOCFEDF_01490 5e-70 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PKOCFEDF_01491 2.2e-78 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PKOCFEDF_01492 2.4e-58 azlD S branched-chain amino acid
PKOCFEDF_01493 3.2e-137 azlC E AzlC protein
PKOCFEDF_01494 1.7e-198 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PKOCFEDF_01495 1.7e-207 hpk31 2.7.13.3 T Histidine kinase
PKOCFEDF_01496 1.8e-122 K response regulator
PKOCFEDF_01497 4.1e-92 S Cupin superfamily (DUF985)
PKOCFEDF_01498 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
PKOCFEDF_01499 2e-157 EGP Major facilitator Superfamily
PKOCFEDF_01500 0.0 copA 3.6.3.54 P P-type ATPase
PKOCFEDF_01501 3.3e-52 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PKOCFEDF_01502 2.5e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PKOCFEDF_01505 5.9e-33 C Flavodoxin
PKOCFEDF_01506 2.1e-199 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PKOCFEDF_01507 3.8e-105 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PKOCFEDF_01508 6.2e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PKOCFEDF_01509 1.1e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PKOCFEDF_01510 7.4e-119 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PKOCFEDF_01511 7.2e-80 M transferase activity, transferring glycosyl groups
PKOCFEDF_01512 2.3e-40 MA20_43635 M Capsular polysaccharide synthesis protein
PKOCFEDF_01513 9.9e-75 epsIIL S Polysaccharide biosynthesis protein
PKOCFEDF_01514 3.9e-30 GT2 M Glycosyltransferase like family 2
PKOCFEDF_01515 1.1e-32 L Transposase
PKOCFEDF_01517 1.4e-13 C Putative TM nitroreductase
PKOCFEDF_01518 1.6e-29 S Domain of unknown function (DUF4767)
PKOCFEDF_01519 1.9e-44 S Tautomerase enzyme
PKOCFEDF_01520 1.2e-32 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PKOCFEDF_01521 1.6e-117 pnb C nitroreductase
PKOCFEDF_01522 6.5e-24 S Alpha/beta hydrolase family
PKOCFEDF_01523 9.8e-77
PKOCFEDF_01524 3.4e-172 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PKOCFEDF_01525 9.7e-92 bioY S BioY family
PKOCFEDF_01526 7.6e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PKOCFEDF_01527 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PKOCFEDF_01528 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PKOCFEDF_01529 1.1e-261 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PKOCFEDF_01530 5e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PKOCFEDF_01531 1.5e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PKOCFEDF_01532 5e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PKOCFEDF_01533 2.7e-129 IQ reductase
PKOCFEDF_01534 4.8e-171 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PKOCFEDF_01535 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PKOCFEDF_01536 1.8e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PKOCFEDF_01537 4.3e-74 marR K Transcriptional regulator, MarR family
PKOCFEDF_01538 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PKOCFEDF_01540 7e-192 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PKOCFEDF_01541 1.1e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PKOCFEDF_01542 3.9e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PKOCFEDF_01543 1.7e-212 arcT 2.6.1.1 E Aminotransferase
PKOCFEDF_01544 9.9e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
PKOCFEDF_01545 2.3e-257 E Arginine ornithine antiporter
PKOCFEDF_01546 2e-238 arcA 3.5.3.6 E Arginine
PKOCFEDF_01547 3.2e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
PKOCFEDF_01548 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PKOCFEDF_01549 2.4e-145 KT YcbB domain
PKOCFEDF_01550 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PKOCFEDF_01551 2.8e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PKOCFEDF_01552 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PKOCFEDF_01553 8.1e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PKOCFEDF_01554 1.2e-145 fat 3.1.2.21 I Acyl-ACP thioesterase
PKOCFEDF_01555 2.1e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PKOCFEDF_01556 1.5e-55 yabA L Involved in initiation control of chromosome replication
PKOCFEDF_01557 4.9e-193 holB 2.7.7.7 L DNA polymerase III
PKOCFEDF_01558 1.2e-52 yaaQ S Cyclic-di-AMP receptor
PKOCFEDF_01559 1.2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PKOCFEDF_01560 4.1e-21 S Protein of unknown function (DUF2508)
PKOCFEDF_01561 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PKOCFEDF_01562 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PKOCFEDF_01563 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PKOCFEDF_01565 4.4e-73 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PKOCFEDF_01566 2.9e-34 nrdH O Glutaredoxin
PKOCFEDF_01567 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKOCFEDF_01568 7.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKOCFEDF_01569 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
PKOCFEDF_01570 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PKOCFEDF_01571 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PKOCFEDF_01572 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PKOCFEDF_01573 1.3e-174 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PKOCFEDF_01574 2.1e-271 cydA 1.10.3.14 C ubiquinol oxidase
PKOCFEDF_01575 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PKOCFEDF_01576 1.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PKOCFEDF_01577 1.7e-243 steT E amino acid
PKOCFEDF_01578 9.7e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PKOCFEDF_01579 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PKOCFEDF_01580 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
PKOCFEDF_01581 6.5e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PKOCFEDF_01582 9.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PKOCFEDF_01583 7.6e-103 sigH K Belongs to the sigma-70 factor family
PKOCFEDF_01584 8.9e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PKOCFEDF_01585 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PKOCFEDF_01586 4e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PKOCFEDF_01587 7.8e-100 ywlG S Belongs to the UPF0340 family
PKOCFEDF_01588 3.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PKOCFEDF_01589 1.1e-203 yacL S domain protein
PKOCFEDF_01590 2.8e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PKOCFEDF_01591 6.4e-96 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PKOCFEDF_01592 2.4e-53 HA62_12640 S GCN5-related N-acetyl-transferase
PKOCFEDF_01593 1.9e-46 L Transposase
PKOCFEDF_01594 2.1e-21 ydaT
PKOCFEDF_01595 1.3e-25 mleP S Sodium Bile acid symporter family
PKOCFEDF_01596 4.9e-171 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_01597 9.8e-30 yoaK S Protein of unknown function (DUF1275)
PKOCFEDF_01598 1.6e-213 P Belongs to the ABC transporter superfamily
PKOCFEDF_01599 1.3e-246 G Bacterial extracellular solute-binding protein
PKOCFEDF_01600 6.5e-151 U Binding-protein-dependent transport system inner membrane component
PKOCFEDF_01601 9.9e-141 U Binding-protein-dependent transport system inner membrane component
PKOCFEDF_01602 5.9e-178 iolT EGP Major facilitator Superfamily
PKOCFEDF_01603 3.4e-162 yxaB GM Polysaccharide pyruvyl transferase
PKOCFEDF_01604 1.4e-121 dkgB S COG0656 Aldo keto reductases, related to diketogulonate reductase
PKOCFEDF_01605 2.2e-65 S Protein of unknown function (DUF1345)
PKOCFEDF_01606 1.7e-128 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PKOCFEDF_01607 9.7e-237 cycA E Amino acid permease
PKOCFEDF_01608 4.9e-38 L Transposase and inactivated derivatives
PKOCFEDF_01609 6.9e-288 mycA 4.2.1.53 S MCRA family
PKOCFEDF_01611 6.8e-256 gor 1.8.1.7 C Glutathione reductase
PKOCFEDF_01612 3.6e-23 L Transposase and inactivated derivatives
PKOCFEDF_01613 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
PKOCFEDF_01614 8.2e-27 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PKOCFEDF_01615 1.2e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PKOCFEDF_01616 1.6e-160 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PKOCFEDF_01617 2.5e-183 fruR3 K Transcriptional regulator, LacI family
PKOCFEDF_01618 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PKOCFEDF_01619 3.3e-222 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PKOCFEDF_01620 3.3e-178
PKOCFEDF_01621 1e-85 2.5.1.74 H UbiA prenyltransferase family
PKOCFEDF_01623 1.4e-125 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PKOCFEDF_01624 1.9e-158 xth 3.1.11.2 L exodeoxyribonuclease III
PKOCFEDF_01625 2.9e-235 kgtP EGP Sugar (and other) transporter
PKOCFEDF_01627 1.1e-109
PKOCFEDF_01628 3.7e-162 S Polyphosphate nucleotide phosphotransferase, PPK2 family
PKOCFEDF_01629 4.6e-163 K LysR substrate binding domain
PKOCFEDF_01630 1.8e-60 GM NmrA-like family
PKOCFEDF_01631 5.2e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
PKOCFEDF_01632 2.5e-291 scrB 3.2.1.26 GH32 G invertase
PKOCFEDF_01633 6.8e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
PKOCFEDF_01634 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
PKOCFEDF_01635 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PKOCFEDF_01636 7.1e-17 nlhH_1 I alpha/beta hydrolase fold
PKOCFEDF_01637 1.1e-23 nlhH_1 I Carboxylesterase family
PKOCFEDF_01638 9e-79 mleR K LysR family
PKOCFEDF_01639 1.2e-230 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PKOCFEDF_01640 1e-182 XK27_09615 S reductase
PKOCFEDF_01641 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
PKOCFEDF_01642 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PKOCFEDF_01643 3.3e-213 frdC 1.3.5.4 C FAD binding domain
PKOCFEDF_01644 7.3e-224 yflS P Sodium:sulfate symporter transmembrane region
PKOCFEDF_01645 7.7e-163 mleR K LysR family transcriptional regulator
PKOCFEDF_01646 2.7e-252 yjjP S Putative threonine/serine exporter
PKOCFEDF_01647 9.7e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
PKOCFEDF_01648 8.6e-187 I Alpha beta
PKOCFEDF_01649 8.8e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PKOCFEDF_01650 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PKOCFEDF_01652 1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PKOCFEDF_01653 2e-310 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
PKOCFEDF_01654 1.3e-136 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PKOCFEDF_01655 6.4e-204 araR K Transcriptional regulator
PKOCFEDF_01656 2.9e-246 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PKOCFEDF_01657 1.8e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PKOCFEDF_01658 1.2e-110 S Domain of unknown function (DUF4811)
PKOCFEDF_01659 4.3e-267 lmrB EGP Major facilitator Superfamily
PKOCFEDF_01660 3.4e-71 merR K MerR HTH family regulatory protein
PKOCFEDF_01661 2.6e-58
PKOCFEDF_01662 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PKOCFEDF_01663 2.4e-215 S CAAX protease self-immunity
PKOCFEDF_01664 8.1e-33 elaA S GNAT family
PKOCFEDF_01665 1.3e-84 usp1 T Belongs to the universal stress protein A family
PKOCFEDF_01666 1.9e-108 S VIT family
PKOCFEDF_01667 2.5e-116 S membrane
PKOCFEDF_01668 6e-163 czcD P cation diffusion facilitator family transporter
PKOCFEDF_01669 1.3e-122 sirR K iron dependent repressor
PKOCFEDF_01670 3.3e-29 cspA K Cold shock protein
PKOCFEDF_01671 7.8e-124 thrE S Putative threonine/serine exporter
PKOCFEDF_01672 2.8e-82 S Threonine/Serine exporter, ThrE
PKOCFEDF_01673 1.1e-113 lssY 3.6.1.27 I phosphatase
PKOCFEDF_01674 8.3e-156 I alpha/beta hydrolase fold
PKOCFEDF_01676 9e-265 lysP E amino acid
PKOCFEDF_01677 1e-116 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PKOCFEDF_01683 3.7e-89 IQ reductase
PKOCFEDF_01684 2.7e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PKOCFEDF_01685 6.8e-53 S ABC-type cobalt transport system, permease component
PKOCFEDF_01686 5.1e-71 thiW S Thiamine-precursor transporter protein (ThiW)
PKOCFEDF_01687 3.1e-35 rmeB K transcriptional regulator, MerR family
PKOCFEDF_01688 2.7e-120 J 2'-5' RNA ligase superfamily
PKOCFEDF_01689 6.9e-130 XK27_07210 6.1.1.6 S B3 4 domain
PKOCFEDF_01690 2.4e-192 adhP 1.1.1.1 C alcohol dehydrogenase
PKOCFEDF_01691 4.7e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PKOCFEDF_01694 2.2e-64 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PKOCFEDF_01695 3.2e-92 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PKOCFEDF_01696 5.3e-26 yitW S Iron-sulfur cluster assembly protein
PKOCFEDF_01697 7e-17 wzy S EpsG family
PKOCFEDF_01698 3.8e-10 epsH S Hexapeptide repeat of succinyl-transferase
PKOCFEDF_01699 1.3e-30 M Glycosyltransferase sugar-binding region containing DXD motif
PKOCFEDF_01701 7.8e-234 yhdG E C-terminus of AA_permease
PKOCFEDF_01702 1.5e-47 uspA T Universal stress protein family
PKOCFEDF_01704 8.5e-90 IQ Oxidoreductase
PKOCFEDF_01705 9.8e-49 tnpR L Resolvase, N terminal domain
PKOCFEDF_01707 3.5e-197 L Belongs to the 'phage' integrase family
PKOCFEDF_01708 6.2e-77 S Protease prsW family
PKOCFEDF_01710 2.5e-240 dinF V MatE
PKOCFEDF_01711 1.8e-89 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PKOCFEDF_01712 1.1e-09 tnp L DDE domain
PKOCFEDF_01713 2.5e-50 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PKOCFEDF_01715 1.1e-240 iolT EGP Major facilitator Superfamily
PKOCFEDF_01716 1.2e-39 yxaB GM Polysaccharide pyruvyl transferase
PKOCFEDF_01717 1e-37 S Cytochrome B5
PKOCFEDF_01720 3.5e-11 ysdA CP ABC-type Na efflux pump, permease component
PKOCFEDF_01721 1.3e-32 natA S ABC transporter, ATP-binding protein
PKOCFEDF_01722 2e-188 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PKOCFEDF_01723 1.8e-175 D Alpha beta
PKOCFEDF_01724 5e-179 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_01725 7.5e-214 patA 2.6.1.1 E Aminotransferase
PKOCFEDF_01726 5.1e-34
PKOCFEDF_01727 0.0 clpL O associated with various cellular activities
PKOCFEDF_01728 5.9e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PKOCFEDF_01729 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PKOCFEDF_01730 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PKOCFEDF_01731 7.5e-163 yvgN C Aldo keto reductase
PKOCFEDF_01732 2.7e-283 glpQ 3.1.4.46 C phosphodiesterase
PKOCFEDF_01733 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
PKOCFEDF_01734 1.1e-177 ybhR V ABC transporter
PKOCFEDF_01735 2.3e-90 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
PKOCFEDF_01736 6.7e-168 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PKOCFEDF_01737 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PKOCFEDF_01738 3.3e-253 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PKOCFEDF_01739 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PKOCFEDF_01740 2.1e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PKOCFEDF_01741 4.2e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PKOCFEDF_01742 1.7e-12 gntT EG gluconate transmembrane transporter activity
PKOCFEDF_01743 1.5e-46
PKOCFEDF_01744 3.2e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
PKOCFEDF_01745 1.3e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PKOCFEDF_01746 5.1e-148 metQ1 P Belongs to the nlpA lipoprotein family
PKOCFEDF_01747 2.2e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PKOCFEDF_01748 6.4e-96 metI P ABC transporter permease
PKOCFEDF_01749 2.7e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PKOCFEDF_01750 6.4e-244 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PKOCFEDF_01751 9.7e-197 brnQ U Component of the transport system for branched-chain amino acids
PKOCFEDF_01752 1.8e-122 iolS C Aldo keto reductase
PKOCFEDF_01753 1.4e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PKOCFEDF_01754 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKOCFEDF_01755 8.5e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
PKOCFEDF_01756 4.5e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKOCFEDF_01758 2.8e-213 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PKOCFEDF_01759 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PKOCFEDF_01760 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PKOCFEDF_01762 4.6e-188 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PKOCFEDF_01763 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PKOCFEDF_01764 9.8e-224 glnP P ABC transporter
PKOCFEDF_01765 1e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKOCFEDF_01766 2.4e-55 ysnF S Heat induced stress protein YflT
PKOCFEDF_01767 5.6e-170 wbbI M transferase activity, transferring glycosyl groups
PKOCFEDF_01768 5.1e-111 IQ Enoyl-(Acyl carrier protein) reductase
PKOCFEDF_01769 5.7e-164 P CorA-like Mg2+ transporter protein
PKOCFEDF_01770 4.4e-49 tnp L MULE transposase domain
PKOCFEDF_01771 2.4e-37 L Transposase
PKOCFEDF_01772 1.2e-12 ytgB S Transglycosylase associated protein
PKOCFEDF_01773 8.2e-94
PKOCFEDF_01774 9.5e-23 S Small integral membrane protein (DUF2273)
PKOCFEDF_01775 1e-72 S cog cog1302
PKOCFEDF_01776 2.5e-46 GT4 M Glycosyl transferases group 1
PKOCFEDF_01777 3.8e-226 L transposase, IS605 OrfB family
PKOCFEDF_01778 3.1e-185 ybiR P Citrate transporter
PKOCFEDF_01779 5.5e-32 L PFAM Integrase catalytic region
PKOCFEDF_01780 7.9e-80
PKOCFEDF_01782 6e-188 ydaM M Glycosyl transferase family group 2
PKOCFEDF_01783 3.4e-123 G Glycosyl hydrolases family 8
PKOCFEDF_01784 8e-135 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
PKOCFEDF_01785 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKOCFEDF_01786 1.6e-103 L transposase, IS605 OrfB family
PKOCFEDF_01787 2.9e-52 tlpA2 L Transposase IS200 like
PKOCFEDF_01788 1.5e-294 ybeC E amino acid
PKOCFEDF_01789 1.2e-134 pnuC H nicotinamide mononucleotide transporter
PKOCFEDF_01790 5.6e-203 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PKOCFEDF_01791 4.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PKOCFEDF_01792 5.3e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PKOCFEDF_01793 4.3e-118 dedA S SNARE associated Golgi protein
PKOCFEDF_01794 0.0 helD 3.6.4.12 L DNA helicase
PKOCFEDF_01795 1.6e-160 EG EamA-like transporter family
PKOCFEDF_01796 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PKOCFEDF_01797 3.4e-135 IQ Dehydrogenase reductase
PKOCFEDF_01798 2.5e-103 2.3.1.128 K acetyltransferase
PKOCFEDF_01799 1.2e-174 coaA 2.7.1.33 F Pantothenic acid kinase
PKOCFEDF_01800 2.4e-130 sptS 2.7.13.3 T Histidine kinase
PKOCFEDF_01801 4.7e-80 K response regulator
PKOCFEDF_01802 8.6e-113 2.7.6.5 T Region found in RelA / SpoT proteins
PKOCFEDF_01803 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PKOCFEDF_01804 1.5e-112
PKOCFEDF_01805 6.2e-105 S Domain of unknown function (DUF4767)
PKOCFEDF_01806 1.4e-53 K Helix-turn-helix domain
PKOCFEDF_01807 1.4e-48 1.3.1.9 S Nitronate monooxygenase
PKOCFEDF_01808 4.5e-79 rocF 3.5.3.1, 3.5.3.11 E Arginase family
PKOCFEDF_01809 1.4e-50 ybjQ S Belongs to the UPF0145 family
PKOCFEDF_01810 3.2e-78 dxs 2.2.1.7 HI 1-deoxy-D-xylulose-5-phosphate synthase
PKOCFEDF_01811 8e-119 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PKOCFEDF_01812 6.8e-122 bm3R1 K Bacterial regulatory proteins, tetR family
PKOCFEDF_01813 0.0 yhcA V ABC transporter, ATP-binding protein
PKOCFEDF_01814 7.4e-48 S FMN_bind
PKOCFEDF_01815 1.5e-34 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PKOCFEDF_01816 1e-39 fhaB M Rib/alpha-like repeat
PKOCFEDF_01817 4.2e-230 XK27_06780 V ABC transporter permease
PKOCFEDF_01818 1.2e-97 XK27_06785 V ABC transporter, ATP-binding protein
PKOCFEDF_01819 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PKOCFEDF_01820 1.4e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PKOCFEDF_01821 1.5e-258 argH 4.3.2.1 E argininosuccinate lyase
PKOCFEDF_01822 2.8e-51 lacA S transferase hexapeptide repeat
PKOCFEDF_01823 2.3e-153 L Thioesterase-like superfamily
PKOCFEDF_01824 3.6e-16 S NADPH-dependent FMN reductase
PKOCFEDF_01825 8.5e-42 S NADPH-dependent FMN reductase
PKOCFEDF_01826 3.8e-236 yfnA E amino acid
PKOCFEDF_01827 1.1e-240 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PKOCFEDF_01829 2.4e-151 mleP3 S Membrane transport protein
PKOCFEDF_01830 3.7e-51 trxA O Belongs to the thioredoxin family
PKOCFEDF_01831 1.6e-252 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
PKOCFEDF_01832 3.1e-204 EGP Major facilitator Superfamily
PKOCFEDF_01833 7.9e-25 ycsG P Natural resistance-associated macrophage protein
PKOCFEDF_01834 1.8e-127 EGP Major facilitator Superfamily
PKOCFEDF_01835 3.4e-126 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PKOCFEDF_01836 4.4e-130 S haloacid dehalogenase-like hydrolase
PKOCFEDF_01837 9.7e-135 L Transposase and inactivated derivatives, IS30 family
PKOCFEDF_01838 1.7e-149 yihY S Belongs to the UPF0761 family
PKOCFEDF_01848 3.1e-23 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PKOCFEDF_01853 1.1e-113 K Transcriptional regulator
PKOCFEDF_01854 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
PKOCFEDF_01855 9e-53 ysxB J Cysteine protease Prp
PKOCFEDF_01856 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PKOCFEDF_01857 8.1e-207 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PKOCFEDF_01858 4.1e-72 yqhY S Asp23 family, cell envelope-related function
PKOCFEDF_01859 1.5e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PKOCFEDF_01860 1.1e-158 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PKOCFEDF_01861 8.2e-255 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PKOCFEDF_01862 1.3e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PKOCFEDF_01863 1.8e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PKOCFEDF_01864 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PKOCFEDF_01865 6.2e-76 argR K Regulates arginine biosynthesis genes
PKOCFEDF_01866 1.8e-306 recN L May be involved in recombinational repair of damaged DNA
PKOCFEDF_01867 2.5e-15
PKOCFEDF_01868 6.7e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PKOCFEDF_01869 2.1e-45 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PKOCFEDF_01870 1.1e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PKOCFEDF_01871 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PKOCFEDF_01872 1.1e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PKOCFEDF_01873 3.8e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PKOCFEDF_01874 1e-128 stp 3.1.3.16 T phosphatase
PKOCFEDF_01875 0.0 KLT serine threonine protein kinase
PKOCFEDF_01876 1.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PKOCFEDF_01877 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PKOCFEDF_01878 1.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
PKOCFEDF_01879 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PKOCFEDF_01880 4e-57 asp S Asp23 family, cell envelope-related function
PKOCFEDF_01881 1.9e-303 yloV S DAK2 domain fusion protein YloV
PKOCFEDF_01882 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PKOCFEDF_01883 1.1e-163 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PKOCFEDF_01884 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PKOCFEDF_01885 3.4e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PKOCFEDF_01886 0.0 smc D Required for chromosome condensation and partitioning
PKOCFEDF_01887 1.3e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PKOCFEDF_01888 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PKOCFEDF_01889 5.8e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PKOCFEDF_01891 5.3e-91
PKOCFEDF_01892 1.3e-128 K Transcriptional regulatory protein, C-terminal domain protein
PKOCFEDF_01893 1.9e-158 pstS P Phosphate
PKOCFEDF_01894 1.6e-152 pstC P probably responsible for the translocation of the substrate across the membrane
PKOCFEDF_01895 1.2e-152 pstA P Phosphate transport system permease protein PstA
PKOCFEDF_01896 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PKOCFEDF_01897 2.3e-122 phoU P Plays a role in the regulation of phosphate uptake
PKOCFEDF_01898 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PKOCFEDF_01899 5.4e-40 ylqC S Belongs to the UPF0109 family
PKOCFEDF_01900 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PKOCFEDF_01901 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PKOCFEDF_01902 3.2e-259 yfnA E Amino Acid
PKOCFEDF_01903 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PKOCFEDF_01904 6.1e-111 ycsI S Protein of unknown function (DUF1445)
PKOCFEDF_01905 1.5e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PKOCFEDF_01906 5.2e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PKOCFEDF_01907 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PKOCFEDF_01908 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PKOCFEDF_01909 1.6e-163 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)