ORF_ID e_value Gene_name EC_number CAZy COGs Description
IOBKPLHJ_00001 1.3e-246 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOBKPLHJ_00002 1.1e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOBKPLHJ_00003 5.9e-35 yaaA S S4 domain protein YaaA
IOBKPLHJ_00004 1.3e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOBKPLHJ_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOBKPLHJ_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOBKPLHJ_00007 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IOBKPLHJ_00008 2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOBKPLHJ_00009 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOBKPLHJ_00010 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IOBKPLHJ_00011 2.1e-71 rplI J Binds to the 23S rRNA
IOBKPLHJ_00012 5.5e-256 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IOBKPLHJ_00013 1.1e-172 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
IOBKPLHJ_00014 1.8e-130 degV S DegV family
IOBKPLHJ_00015 1.5e-35 degV S DegV family
IOBKPLHJ_00016 1.6e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IOBKPLHJ_00017 1e-16 S CsbD-like
IOBKPLHJ_00018 1e-30
IOBKPLHJ_00019 2.6e-238 I Protein of unknown function (DUF2974)
IOBKPLHJ_00021 6.7e-97 cadD P Cadmium resistance transporter
IOBKPLHJ_00022 1.6e-58 cadX K helix_turn_helix, Arsenical Resistance Operon Repressor
IOBKPLHJ_00023 5e-184
IOBKPLHJ_00024 4.6e-54
IOBKPLHJ_00025 1.8e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOBKPLHJ_00026 8.6e-93
IOBKPLHJ_00027 4.9e-184 repB EP Plasmid replication protein
IOBKPLHJ_00028 1.5e-31
IOBKPLHJ_00029 4e-234 L Belongs to the 'phage' integrase family
IOBKPLHJ_00030 1.3e-31
IOBKPLHJ_00031 6.5e-69 doc S Fic/DOC family
IOBKPLHJ_00032 2e-19 S Protein of unknown function (DUF3923)
IOBKPLHJ_00035 3.9e-161 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
IOBKPLHJ_00036 2.3e-278 pipD E Dipeptidase
IOBKPLHJ_00037 1.3e-230 S LPXTG cell wall anchor motif
IOBKPLHJ_00038 3.6e-151 S Putative ABC-transporter type IV
IOBKPLHJ_00039 2.9e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
IOBKPLHJ_00040 4.5e-86 S ECF transporter, substrate-specific component
IOBKPLHJ_00041 2.4e-55 S Domain of unknown function (DUF4430)
IOBKPLHJ_00042 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
IOBKPLHJ_00043 7.1e-176 K AI-2E family transporter
IOBKPLHJ_00044 3.6e-105 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
IOBKPLHJ_00045 5.5e-15
IOBKPLHJ_00046 7.6e-247 G Major Facilitator
IOBKPLHJ_00047 1.7e-52
IOBKPLHJ_00048 2.6e-135 XK27_08845 S ABC transporter, ATP-binding protein
IOBKPLHJ_00049 2.6e-126 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IOBKPLHJ_00050 1.5e-178 ABC-SBP S ABC transporter
IOBKPLHJ_00051 4e-138 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOBKPLHJ_00052 0.0 tetP J elongation factor G
IOBKPLHJ_00053 3.6e-151 3.1.3.102, 3.1.3.104 S hydrolase
IOBKPLHJ_00054 6.5e-30 S endonuclease exonuclease phosphatase family protein
IOBKPLHJ_00055 2.7e-134 S endonuclease exonuclease phosphatase family protein
IOBKPLHJ_00056 2.8e-15 S endonuclease exonuclease phosphatase family protein
IOBKPLHJ_00057 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOBKPLHJ_00058 1.8e-153 xth 3.1.11.2 L exodeoxyribonuclease III
IOBKPLHJ_00059 1e-273 E amino acid
IOBKPLHJ_00060 0.0 L Helicase C-terminal domain protein
IOBKPLHJ_00061 6e-82 S COG NOG38524 non supervised orthologous group
IOBKPLHJ_00063 6e-82 S COG NOG38524 non supervised orthologous group
IOBKPLHJ_00065 6e-82 S COG NOG38524 non supervised orthologous group
IOBKPLHJ_00067 2.2e-51 K LysR substrate binding domain
IOBKPLHJ_00068 4.2e-56 1.3.5.4 S FMN_bind
IOBKPLHJ_00069 2.8e-229 1.3.5.4 C FAD binding domain
IOBKPLHJ_00070 5.6e-115 K Transcriptional regulator, LysR family
IOBKPLHJ_00071 4.5e-38 S Cytochrome B5
IOBKPLHJ_00072 3.3e-166 arbZ I Phosphate acyltransferases
IOBKPLHJ_00073 8.4e-184 arbY M Glycosyl transferase family 8
IOBKPLHJ_00074 2.2e-187 arbY M Glycosyl transferase family 8
IOBKPLHJ_00075 1.1e-158 arbx M Glycosyl transferase family 8
IOBKPLHJ_00076 2.1e-148 arbV 2.3.1.51 I Acyl-transferase
IOBKPLHJ_00077 3e-78
IOBKPLHJ_00078 2.8e-288 P ABC transporter
IOBKPLHJ_00079 1.4e-295 V ABC-type multidrug transport system, ATPase and permease components
IOBKPLHJ_00081 9.7e-132 K response regulator
IOBKPLHJ_00082 6.5e-305 vicK 2.7.13.3 T Histidine kinase
IOBKPLHJ_00083 1.5e-258 yycH S YycH protein
IOBKPLHJ_00084 9.4e-147 yycI S YycH protein
IOBKPLHJ_00085 1.1e-149 vicX 3.1.26.11 S domain protein
IOBKPLHJ_00087 2.4e-142 htrA 3.4.21.107 O serine protease
IOBKPLHJ_00088 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOBKPLHJ_00089 2.4e-150 K Helix-turn-helix XRE-family like proteins
IOBKPLHJ_00091 2.1e-258 S CAAX protease self-immunity
IOBKPLHJ_00092 4.5e-18
IOBKPLHJ_00093 1.1e-121
IOBKPLHJ_00094 1.3e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IOBKPLHJ_00095 8.9e-92 P Cobalt transport protein
IOBKPLHJ_00096 6e-252 cbiO1 S ABC transporter, ATP-binding protein
IOBKPLHJ_00097 3.9e-173 K helix_turn_helix, arabinose operon control protein
IOBKPLHJ_00098 7.8e-163 htpX O Belongs to the peptidase M48B family
IOBKPLHJ_00099 1.4e-93 lemA S LemA family
IOBKPLHJ_00100 5.6e-195 ybiR P Citrate transporter
IOBKPLHJ_00101 2.2e-69 S Iron-sulphur cluster biosynthesis
IOBKPLHJ_00102 1.1e-301 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IOBKPLHJ_00103 1.2e-17
IOBKPLHJ_00104 1.6e-152
IOBKPLHJ_00106 1.6e-228 ydaM M Glycosyl transferase family group 2
IOBKPLHJ_00107 1.5e-211 G Glycosyl hydrolases family 8
IOBKPLHJ_00108 3.7e-122 yfbR S HD containing hydrolase-like enzyme
IOBKPLHJ_00109 4e-161 L HNH nucleases
IOBKPLHJ_00110 1.2e-182 S Protein of unknown function (DUF805)
IOBKPLHJ_00111 2.1e-137 glnQ E ABC transporter, ATP-binding protein
IOBKPLHJ_00112 2.5e-292 glnP P ABC transporter permease
IOBKPLHJ_00113 5.5e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IOBKPLHJ_00114 2.5e-64 yeaO S Protein of unknown function, DUF488
IOBKPLHJ_00115 5.8e-138 terC P Integral membrane protein TerC family
IOBKPLHJ_00116 2.6e-81 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IOBKPLHJ_00117 2.3e-133 cobB K SIR2 family
IOBKPLHJ_00118 1.7e-84
IOBKPLHJ_00119 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOBKPLHJ_00120 1.9e-180 S Alpha/beta hydrolase of unknown function (DUF915)
IOBKPLHJ_00121 2.2e-142 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOBKPLHJ_00122 7.7e-137 ypuA S Protein of unknown function (DUF1002)
IOBKPLHJ_00123 7.3e-160 2.4.1.293 GT2 M Glycosyltransferase like family 2
IOBKPLHJ_00124 5.6e-126 S Alpha/beta hydrolase family
IOBKPLHJ_00125 8.3e-148 K Helix-turn-helix XRE-family like proteins
IOBKPLHJ_00126 2.9e-51
IOBKPLHJ_00127 1.2e-263 L COG2963 Transposase and inactivated derivatives
IOBKPLHJ_00128 4.1e-46
IOBKPLHJ_00129 3.3e-43 3.6.4.12
IOBKPLHJ_00130 1.6e-76 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IOBKPLHJ_00131 4.4e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOBKPLHJ_00132 2.1e-123 luxT K Bacterial regulatory proteins, tetR family
IOBKPLHJ_00133 2.1e-130
IOBKPLHJ_00134 1.4e-257 glnPH2 P ABC transporter permease
IOBKPLHJ_00135 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOBKPLHJ_00136 6.6e-229 S Cysteine-rich secretory protein family
IOBKPLHJ_00137 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IOBKPLHJ_00138 7.2e-90
IOBKPLHJ_00139 4.4e-203 yibE S overlaps another CDS with the same product name
IOBKPLHJ_00140 2.4e-131 yibF S overlaps another CDS with the same product name
IOBKPLHJ_00141 5.5e-52 I alpha/beta hydrolase fold
IOBKPLHJ_00142 2.7e-96 I alpha/beta hydrolase fold
IOBKPLHJ_00143 0.0 G Belongs to the glycosyl hydrolase 31 family
IOBKPLHJ_00144 5.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOBKPLHJ_00145 5.3e-39 ntd 2.4.2.6 F Nucleoside
IOBKPLHJ_00146 2.4e-29 ntd 2.4.2.6 F Nucleoside
IOBKPLHJ_00147 1.1e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOBKPLHJ_00148 2.2e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
IOBKPLHJ_00149 1.6e-85 uspA T universal stress protein
IOBKPLHJ_00150 1.5e-164 phnD P Phosphonate ABC transporter
IOBKPLHJ_00151 2.3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IOBKPLHJ_00152 4.8e-132 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IOBKPLHJ_00153 1.9e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IOBKPLHJ_00154 8.6e-107 tag 3.2.2.20 L glycosylase
IOBKPLHJ_00155 1.5e-83
IOBKPLHJ_00156 2.2e-273 S Calcineurin-like phosphoesterase
IOBKPLHJ_00157 0.0 asnB 6.3.5.4 E Asparagine synthase
IOBKPLHJ_00158 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
IOBKPLHJ_00159 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IOBKPLHJ_00160 8.1e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOBKPLHJ_00161 6.5e-99 S Iron-sulfur cluster assembly protein
IOBKPLHJ_00162 1.1e-233 XK27_04775 S PAS domain
IOBKPLHJ_00163 1.1e-228 yttB EGP Major facilitator Superfamily
IOBKPLHJ_00164 0.0 pepO 3.4.24.71 O Peptidase family M13
IOBKPLHJ_00165 2.1e-188 kup P Transport of potassium into the cell
IOBKPLHJ_00166 2.6e-161 kup P Transport of potassium into the cell
IOBKPLHJ_00167 1.9e-69
IOBKPLHJ_00168 6.9e-11
IOBKPLHJ_00169 3e-203 S SLAP domain
IOBKPLHJ_00170 8.6e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
IOBKPLHJ_00171 2.6e-255 ica2 GT2 M Glycosyl transferase family group 2
IOBKPLHJ_00172 2.2e-175
IOBKPLHJ_00173 2.1e-228 S SLAP domain
IOBKPLHJ_00174 1.5e-13 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOBKPLHJ_00175 3.3e-180 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOBKPLHJ_00176 7.2e-211 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
IOBKPLHJ_00177 0.0 yjbQ P TrkA C-terminal domain protein
IOBKPLHJ_00178 9.8e-180 S Oxidoreductase family, NAD-binding Rossmann fold
IOBKPLHJ_00179 7.4e-141
IOBKPLHJ_00180 3.4e-135
IOBKPLHJ_00181 2.5e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOBKPLHJ_00182 1.8e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOBKPLHJ_00183 1.6e-102 G Aldose 1-epimerase
IOBKPLHJ_00184 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOBKPLHJ_00185 6.4e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOBKPLHJ_00186 0.0 XK27_08315 M Sulfatase
IOBKPLHJ_00187 6.2e-268 S Fibronectin type III domain
IOBKPLHJ_00188 3.3e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOBKPLHJ_00189 3.3e-56
IOBKPLHJ_00191 7.2e-258 pepC 3.4.22.40 E aminopeptidase
IOBKPLHJ_00192 1.2e-125 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOBKPLHJ_00193 6.1e-291 oppA E ABC transporter, substratebinding protein
IOBKPLHJ_00194 4.6e-307 oppA E ABC transporter, substratebinding protein
IOBKPLHJ_00195 7.5e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOBKPLHJ_00196 1.1e-143 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOBKPLHJ_00197 4e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOBKPLHJ_00198 2.2e-201 oppD P Belongs to the ABC transporter superfamily
IOBKPLHJ_00199 1.9e-175 oppF P Belongs to the ABC transporter superfamily
IOBKPLHJ_00200 2.3e-256 pepC 3.4.22.40 E aminopeptidase
IOBKPLHJ_00201 2.4e-69 hsp O Belongs to the small heat shock protein (HSP20) family
IOBKPLHJ_00202 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOBKPLHJ_00203 1.3e-114
IOBKPLHJ_00205 4.2e-112 E Belongs to the SOS response-associated peptidase family
IOBKPLHJ_00206 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOBKPLHJ_00207 6.5e-92 comEB 3.5.4.12 F MafB19-like deaminase
IOBKPLHJ_00208 3.4e-109 S TPM domain
IOBKPLHJ_00209 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IOBKPLHJ_00210 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOBKPLHJ_00211 3.5e-148 tatD L hydrolase, TatD family
IOBKPLHJ_00212 1.6e-92 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOBKPLHJ_00213 1.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOBKPLHJ_00214 3.5e-39 veg S Biofilm formation stimulator VEG
IOBKPLHJ_00215 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IOBKPLHJ_00216 1.4e-211 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOBKPLHJ_00217 9.6e-89 S SLAP domain
IOBKPLHJ_00218 1.1e-95 S SLAP domain
IOBKPLHJ_00219 1.5e-86
IOBKPLHJ_00220 7.3e-239 S SLAP domain
IOBKPLHJ_00221 4.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOBKPLHJ_00222 5.2e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBKPLHJ_00223 7.7e-129 K Helix-turn-helix domain, rpiR family
IOBKPLHJ_00224 1.2e-231 ptcC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBKPLHJ_00225 3.3e-169 2.7.1.2 GK ROK family
IOBKPLHJ_00226 3.9e-44
IOBKPLHJ_00227 7.2e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOBKPLHJ_00228 9.5e-68 S Domain of unknown function (DUF1934)
IOBKPLHJ_00229 3.3e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOBKPLHJ_00230 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOBKPLHJ_00231 1.8e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOBKPLHJ_00232 2.3e-278 pipD E Dipeptidase
IOBKPLHJ_00233 7.4e-160 msmR K AraC-like ligand binding domain
IOBKPLHJ_00234 7e-107 S Protein of unknown function (DUF1211)
IOBKPLHJ_00235 5.2e-221 pbuX F xanthine permease
IOBKPLHJ_00236 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOBKPLHJ_00237 1.5e-135 K DNA-binding helix-turn-helix protein
IOBKPLHJ_00238 7.5e-172 K Helix-turn-helix
IOBKPLHJ_00239 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IOBKPLHJ_00240 2.5e-155 cylA V ABC transporter
IOBKPLHJ_00241 4e-148 cylB V ABC-2 type transporter
IOBKPLHJ_00242 1.3e-73 K LytTr DNA-binding domain
IOBKPLHJ_00243 2.7e-43 S Protein of unknown function (DUF3021)
IOBKPLHJ_00244 1.9e-89 XK27_09675 K Acetyltransferase (GNAT) domain
IOBKPLHJ_00246 7e-135 S B3 4 domain
IOBKPLHJ_00247 5.4e-90 lmrB P Belongs to the major facilitator superfamily
IOBKPLHJ_00248 1.6e-32 P Belongs to the major facilitator superfamily
IOBKPLHJ_00249 1.9e-30
IOBKPLHJ_00250 7.7e-82 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOBKPLHJ_00251 2.5e-28 K NAD+ binding
IOBKPLHJ_00253 2.1e-96
IOBKPLHJ_00254 3.7e-51
IOBKPLHJ_00255 6.7e-44
IOBKPLHJ_00256 1.3e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOBKPLHJ_00257 1.1e-300 ybeC E amino acid
IOBKPLHJ_00258 3.7e-159 G Sucrose-6F-phosphate phosphohydrolase
IOBKPLHJ_00259 3.6e-156 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
IOBKPLHJ_00260 2.5e-163 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
IOBKPLHJ_00261 1.9e-39 rpmE2 J Ribosomal protein L31
IOBKPLHJ_00262 7.7e-263 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOBKPLHJ_00263 3.9e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOBKPLHJ_00264 7.6e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOBKPLHJ_00265 9e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOBKPLHJ_00266 1.1e-127 S (CBS) domain
IOBKPLHJ_00267 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOBKPLHJ_00268 1.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOBKPLHJ_00269 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOBKPLHJ_00270 5.9e-149 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOBKPLHJ_00271 2.4e-34 yabO J S4 domain protein
IOBKPLHJ_00272 1.1e-57 divIC D Septum formation initiator
IOBKPLHJ_00273 2.8e-63 yabR J S1 RNA binding domain
IOBKPLHJ_00274 2.2e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOBKPLHJ_00275 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOBKPLHJ_00276 2.6e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOBKPLHJ_00277 1.4e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOBKPLHJ_00278 1.5e-302 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IOBKPLHJ_00279 7.8e-08
IOBKPLHJ_00281 4.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
IOBKPLHJ_00282 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOBKPLHJ_00283 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOBKPLHJ_00284 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOBKPLHJ_00285 7.9e-123 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IOBKPLHJ_00286 1.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOBKPLHJ_00287 3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOBKPLHJ_00288 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOBKPLHJ_00289 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IOBKPLHJ_00290 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOBKPLHJ_00291 4.6e-106 rplD J Forms part of the polypeptide exit tunnel
IOBKPLHJ_00292 1.2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOBKPLHJ_00293 4.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOBKPLHJ_00294 2.7e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOBKPLHJ_00295 3.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOBKPLHJ_00296 4.9e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOBKPLHJ_00297 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOBKPLHJ_00298 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IOBKPLHJ_00299 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOBKPLHJ_00300 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOBKPLHJ_00301 4.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOBKPLHJ_00302 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOBKPLHJ_00303 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOBKPLHJ_00304 9.3e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOBKPLHJ_00305 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOBKPLHJ_00306 2.1e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOBKPLHJ_00307 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOBKPLHJ_00308 2.3e-24 rpmD J Ribosomal protein L30
IOBKPLHJ_00309 2e-71 rplO J Binds to the 23S rRNA
IOBKPLHJ_00310 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOBKPLHJ_00311 2.3e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOBKPLHJ_00312 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOBKPLHJ_00313 2.7e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IOBKPLHJ_00314 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOBKPLHJ_00315 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOBKPLHJ_00316 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOBKPLHJ_00317 8.2e-61 rplQ J Ribosomal protein L17
IOBKPLHJ_00318 2.8e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOBKPLHJ_00319 2.4e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOBKPLHJ_00320 9.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOBKPLHJ_00321 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOBKPLHJ_00322 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOBKPLHJ_00323 1.3e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
IOBKPLHJ_00324 1e-198 L Phage integrase family
IOBKPLHJ_00325 6.5e-27
IOBKPLHJ_00326 5.5e-211 repB EP Plasmid replication protein
IOBKPLHJ_00327 6.6e-45
IOBKPLHJ_00328 3.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOBKPLHJ_00329 1.1e-52
IOBKPLHJ_00331 0.0 V Type II restriction enzyme, methylase subunits
IOBKPLHJ_00332 6.9e-65 S YjcQ protein
IOBKPLHJ_00333 1.7e-13
IOBKPLHJ_00334 2.8e-11
IOBKPLHJ_00335 6.1e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IOBKPLHJ_00336 2.5e-118 3.1.3.102, 3.1.3.104, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOBKPLHJ_00337 5.8e-111 S membrane transporter protein
IOBKPLHJ_00338 3.4e-126 pgm3 5.4.2.11 G Belongs to the phosphoglycerate mutase family
IOBKPLHJ_00339 2.1e-163 czcD P cation diffusion facilitator family transporter
IOBKPLHJ_00340 2.2e-19
IOBKPLHJ_00341 1.5e-118 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOBKPLHJ_00342 6.4e-184 S AAA domain
IOBKPLHJ_00343 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
IOBKPLHJ_00344 7e-52
IOBKPLHJ_00345 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IOBKPLHJ_00346 9.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOBKPLHJ_00347 9.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOBKPLHJ_00348 6.8e-278 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOBKPLHJ_00349 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOBKPLHJ_00350 2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOBKPLHJ_00351 3.5e-94 sigH K Belongs to the sigma-70 factor family
IOBKPLHJ_00352 2.2e-34
IOBKPLHJ_00353 3.5e-114
IOBKPLHJ_00354 2.4e-286 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IOBKPLHJ_00355 8.1e-173 K helix_turn_helix, arabinose operon control protein
IOBKPLHJ_00356 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOBKPLHJ_00357 7.8e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOBKPLHJ_00358 6.2e-102 nusG K Participates in transcription elongation, termination and antitermination
IOBKPLHJ_00359 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOBKPLHJ_00360 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOBKPLHJ_00361 1.5e-158 pstS P Phosphate
IOBKPLHJ_00362 5.2e-176 pstC P probably responsible for the translocation of the substrate across the membrane
IOBKPLHJ_00363 2.6e-155 pstA P Phosphate transport system permease protein PstA
IOBKPLHJ_00364 4.2e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOBKPLHJ_00365 7e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOBKPLHJ_00366 2e-118 phoU P Plays a role in the regulation of phosphate uptake
IOBKPLHJ_00367 5e-210 yfdV S Membrane transport protein
IOBKPLHJ_00368 5.4e-09
IOBKPLHJ_00369 1.6e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOBKPLHJ_00370 2.2e-47 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOBKPLHJ_00371 1.5e-123 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
IOBKPLHJ_00372 6.4e-116 rsmC 2.1.1.172 J Methyltransferase
IOBKPLHJ_00373 1.4e-23
IOBKPLHJ_00374 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOBKPLHJ_00375 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOBKPLHJ_00376 3.5e-224 tnpB L Putative transposase DNA-binding domain
IOBKPLHJ_00377 2e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOBKPLHJ_00378 3.7e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOBKPLHJ_00379 1.1e-34 S Protein of unknown function (DUF2508)
IOBKPLHJ_00380 2.3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOBKPLHJ_00381 5.8e-52 yaaQ S Cyclic-di-AMP receptor
IOBKPLHJ_00382 2.6e-155 holB 2.7.7.7 L DNA polymerase III
IOBKPLHJ_00383 3e-60 yabA L Involved in initiation control of chromosome replication
IOBKPLHJ_00384 8.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOBKPLHJ_00385 4.8e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
IOBKPLHJ_00386 7.6e-86 S ECF transporter, substrate-specific component
IOBKPLHJ_00387 1.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IOBKPLHJ_00388 7.3e-106 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IOBKPLHJ_00389 1.1e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOBKPLHJ_00390 1.3e-131 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOBKPLHJ_00391 2.1e-182 S Oxidoreductase family, NAD-binding Rossmann fold
IOBKPLHJ_00392 4.9e-128 yegW K UTRA
IOBKPLHJ_00393 6.5e-234 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IOBKPLHJ_00394 4.3e-266 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IOBKPLHJ_00395 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IOBKPLHJ_00396 0.0 uup S ABC transporter, ATP-binding protein
IOBKPLHJ_00397 1.3e-111 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOBKPLHJ_00398 1e-184 scrR K helix_turn _helix lactose operon repressor
IOBKPLHJ_00399 5.6e-296 scrB 3.2.1.26 GH32 G invertase
IOBKPLHJ_00400 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
IOBKPLHJ_00401 5.8e-75
IOBKPLHJ_00402 1.1e-77 XK27_02470 K LytTr DNA-binding domain
IOBKPLHJ_00403 6.9e-128 liaI S membrane
IOBKPLHJ_00404 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOBKPLHJ_00405 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOBKPLHJ_00406 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOBKPLHJ_00407 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOBKPLHJ_00408 2.7e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOBKPLHJ_00409 4.6e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOBKPLHJ_00410 1.1e-47 yajC U Preprotein translocase
IOBKPLHJ_00411 5.3e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOBKPLHJ_00412 2.1e-213 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOBKPLHJ_00413 6.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IOBKPLHJ_00414 3.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOBKPLHJ_00415 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOBKPLHJ_00416 2e-42 yrzL S Belongs to the UPF0297 family
IOBKPLHJ_00417 2.7e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOBKPLHJ_00418 1.4e-50 yrzB S Belongs to the UPF0473 family
IOBKPLHJ_00419 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOBKPLHJ_00420 6e-54 trxA O Belongs to the thioredoxin family
IOBKPLHJ_00421 4e-36 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOBKPLHJ_00422 2.3e-69 yslB S Protein of unknown function (DUF2507)
IOBKPLHJ_00423 3.8e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOBKPLHJ_00424 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOBKPLHJ_00425 8.2e-130 ykuT M mechanosensitive ion channel
IOBKPLHJ_00426 3.6e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOBKPLHJ_00427 2.1e-45
IOBKPLHJ_00428 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOBKPLHJ_00429 2.9e-182 ccpA K catabolite control protein A
IOBKPLHJ_00430 3.9e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOBKPLHJ_00431 1.9e-55
IOBKPLHJ_00432 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IOBKPLHJ_00433 1.3e-81 yutD S Protein of unknown function (DUF1027)
IOBKPLHJ_00434 2.2e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOBKPLHJ_00435 1.1e-107 S Protein of unknown function (DUF1461)
IOBKPLHJ_00436 2.3e-116 dedA S SNARE-like domain protein
IOBKPLHJ_00437 1.1e-150 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IOBKPLHJ_00440 6e-82 S COG NOG38524 non supervised orthologous group
IOBKPLHJ_00457 7.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
IOBKPLHJ_00458 0.0 L Helicase C-terminal domain protein
IOBKPLHJ_00459 1.6e-45 L Helicase C-terminal domain protein
IOBKPLHJ_00471 2.3e-223 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
IOBKPLHJ_00472 2.9e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
IOBKPLHJ_00473 4.7e-180 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOBKPLHJ_00474 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOBKPLHJ_00475 7.5e-25 secG U Preprotein translocase
IOBKPLHJ_00476 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOBKPLHJ_00477 7.4e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOBKPLHJ_00478 6e-82 S COG NOG38524 non supervised orthologous group
IOBKPLHJ_00483 2.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOBKPLHJ_00484 2.9e-260 qacA EGP Major facilitator Superfamily
IOBKPLHJ_00485 6.2e-29 cydA 1.10.3.14 C ubiquinol oxidase
IOBKPLHJ_00486 2.3e-116 ndh 1.6.99.3 C NADH dehydrogenase
IOBKPLHJ_00487 4.4e-91 ndh 1.6.99.3 C NADH dehydrogenase
IOBKPLHJ_00488 3.9e-119 3.6.1.27 I Acid phosphatase homologues
IOBKPLHJ_00489 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOBKPLHJ_00490 6.4e-296 ytgP S Polysaccharide biosynthesis protein
IOBKPLHJ_00491 4.8e-16
IOBKPLHJ_00492 5.5e-71 K transcriptional regulator
IOBKPLHJ_00493 2.8e-17 K transcriptional regulator
IOBKPLHJ_00494 0.0 sprD D Domain of Unknown Function (DUF1542)
IOBKPLHJ_00495 3.8e-80 yphH S Cupin domain
IOBKPLHJ_00496 0.0 S domain, Protein
IOBKPLHJ_00497 9.1e-40 S Enterocin A Immunity
IOBKPLHJ_00498 7e-258 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
IOBKPLHJ_00499 3e-54 yvlA
IOBKPLHJ_00500 5.5e-197 V Beta-lactamase
IOBKPLHJ_00501 6.4e-54 pspC KT PspC domain
IOBKPLHJ_00503 1.7e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IOBKPLHJ_00504 8.1e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOBKPLHJ_00505 6.9e-127 M ErfK YbiS YcfS YnhG
IOBKPLHJ_00506 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IOBKPLHJ_00507 2.3e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IOBKPLHJ_00508 4.1e-192 5.3.3.2 C FMN-dependent dehydrogenase
IOBKPLHJ_00509 6.8e-119
IOBKPLHJ_00510 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOBKPLHJ_00511 2.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOBKPLHJ_00512 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IOBKPLHJ_00513 6.8e-54 yheA S Belongs to the UPF0342 family
IOBKPLHJ_00514 2.4e-231 yhaO L Ser Thr phosphatase family protein
IOBKPLHJ_00515 0.0 L AAA domain
IOBKPLHJ_00516 8.4e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOBKPLHJ_00517 1.1e-148 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOBKPLHJ_00518 1.4e-56
IOBKPLHJ_00519 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
IOBKPLHJ_00520 2e-135 ecsA V ABC transporter, ATP-binding protein
IOBKPLHJ_00521 7.4e-201 ecsB U ABC transporter
IOBKPLHJ_00522 1.5e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOBKPLHJ_00523 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IOBKPLHJ_00524 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOBKPLHJ_00525 3.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IOBKPLHJ_00526 0.0
IOBKPLHJ_00527 1.7e-148 ybbH K Helix-turn-helix domain, rpiR family
IOBKPLHJ_00528 1.2e-29 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IOBKPLHJ_00529 5.5e-295 G phosphotransferase system
IOBKPLHJ_00530 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBKPLHJ_00531 3.3e-91 S Membrane
IOBKPLHJ_00532 6.6e-167 rocF 3.5.3.1, 3.5.3.11 E Arginase family
IOBKPLHJ_00533 1.1e-237 mepA V MATE efflux family protein
IOBKPLHJ_00534 1.2e-97 L Putative transposase DNA-binding domain
IOBKPLHJ_00535 1.9e-112 L Putative transposase DNA-binding domain
IOBKPLHJ_00536 1.2e-177 S SLAP domain
IOBKPLHJ_00537 7.9e-293 M Peptidase family M1 domain
IOBKPLHJ_00538 2.4e-194 S Bacteriocin helveticin-J
IOBKPLHJ_00539 1.1e-50 L RelB antitoxin
IOBKPLHJ_00540 6.6e-102 qmcA O prohibitin homologues
IOBKPLHJ_00541 7.3e-30 qmcA O prohibitin homologues
IOBKPLHJ_00542 1.1e-124 darA C Flavodoxin
IOBKPLHJ_00543 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IOBKPLHJ_00544 9.6e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOBKPLHJ_00545 3.6e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOBKPLHJ_00546 2.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IOBKPLHJ_00547 7.6e-39 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOBKPLHJ_00548 6.1e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOBKPLHJ_00549 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOBKPLHJ_00550 1.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOBKPLHJ_00551 2e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IOBKPLHJ_00552 2.7e-111 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOBKPLHJ_00553 5e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IOBKPLHJ_00554 1e-248 purD 6.3.4.13 F Belongs to the GARS family
IOBKPLHJ_00555 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOBKPLHJ_00556 4.8e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOBKPLHJ_00557 6.9e-107 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOBKPLHJ_00558 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOBKPLHJ_00559 1.7e-251 dnaB L Replication initiation and membrane attachment
IOBKPLHJ_00560 6.9e-167 dnaI L Primosomal protein DnaI
IOBKPLHJ_00561 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOBKPLHJ_00562 5.6e-74 K LytTr DNA-binding domain
IOBKPLHJ_00563 5.7e-71 S Protein of unknown function (DUF3021)
IOBKPLHJ_00564 3.2e-92
IOBKPLHJ_00565 3.7e-73 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOBKPLHJ_00566 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IOBKPLHJ_00567 1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOBKPLHJ_00568 3.5e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IOBKPLHJ_00569 1.9e-198 tnpB L Putative transposase DNA-binding domain
IOBKPLHJ_00570 1.6e-93 yqeG S HAD phosphatase, family IIIA
IOBKPLHJ_00571 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
IOBKPLHJ_00572 9.8e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOBKPLHJ_00573 1.4e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IOBKPLHJ_00574 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOBKPLHJ_00575 2.7e-216 ylbM S Belongs to the UPF0348 family
IOBKPLHJ_00576 2.4e-98 yceD S Uncharacterized ACR, COG1399
IOBKPLHJ_00577 2.5e-127 K response regulator
IOBKPLHJ_00578 1.9e-249 arlS 2.7.13.3 T Histidine kinase
IOBKPLHJ_00579 4.3e-159 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOBKPLHJ_00580 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IOBKPLHJ_00581 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOBKPLHJ_00582 1.4e-62 yodB K Transcriptional regulator, HxlR family
IOBKPLHJ_00583 1.2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOBKPLHJ_00584 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOBKPLHJ_00585 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOBKPLHJ_00586 6.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
IOBKPLHJ_00587 3.6e-254 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOBKPLHJ_00588 1.1e-12 ltrA S Bacterial low temperature requirement A protein (LtrA)
IOBKPLHJ_00589 1.7e-35 ltrA S Bacterial low temperature requirement A protein (LtrA)
IOBKPLHJ_00590 0.0 O Belongs to the peptidase S8 family
IOBKPLHJ_00591 2.3e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
IOBKPLHJ_00592 0.0 S membrane
IOBKPLHJ_00593 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IOBKPLHJ_00594 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOBKPLHJ_00595 1.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOBKPLHJ_00596 1.2e-118 gluP 3.4.21.105 S Rhomboid family
IOBKPLHJ_00597 1.6e-32 yqgQ S Bacterial protein of unknown function (DUF910)
IOBKPLHJ_00598 3.3e-65 yqhL P Rhodanese-like protein
IOBKPLHJ_00599 4.7e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOBKPLHJ_00600 9.3e-239 ynbB 4.4.1.1 P aluminum resistance
IOBKPLHJ_00601 9.8e-263 glnA 6.3.1.2 E glutamine synthetase
IOBKPLHJ_00602 5.5e-133 ybbM S Uncharacterised protein family (UPF0014)
IOBKPLHJ_00603 1.8e-116 ybbL S ABC transporter, ATP-binding protein
IOBKPLHJ_00604 4e-167
IOBKPLHJ_00605 4.1e-152
IOBKPLHJ_00608 1.9e-248 lmrB EGP Major facilitator Superfamily
IOBKPLHJ_00609 7.4e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBKPLHJ_00610 1.6e-258 glpK_1 2.7.1.30 G FGGY family of carbohydrate kinases, C-terminal domain
IOBKPLHJ_00611 1.3e-176 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
IOBKPLHJ_00612 1.2e-154 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
IOBKPLHJ_00613 6e-188 purR13 K Bacterial regulatory proteins, lacI family
IOBKPLHJ_00614 4.6e-224 L Putative transposase DNA-binding domain
IOBKPLHJ_00615 1.7e-289 G isomerase
IOBKPLHJ_00616 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOBKPLHJ_00617 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOBKPLHJ_00618 2.7e-277 rbsA 3.6.3.17 G ABC transporter
IOBKPLHJ_00620 2e-147 rbsC U Belongs to the binding-protein-dependent transport system permease family
IOBKPLHJ_00621 5.7e-175 rbsB G Periplasmic binding protein domain
IOBKPLHJ_00622 2e-257 G Protein of unknown function (DUF4038)
IOBKPLHJ_00623 5.7e-155 licT K CAT RNA binding domain
IOBKPLHJ_00624 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOBKPLHJ_00625 7.3e-177 I alpha/beta hydrolase fold
IOBKPLHJ_00626 1.1e-77 G YdjC-like protein
IOBKPLHJ_00627 2.1e-263 L COG2963 Transposase and inactivated derivatives
IOBKPLHJ_00628 8.1e-60 G polysaccharide catabolic process
IOBKPLHJ_00629 0.0 3.2.1.40 G Alpha-L-rhamnosidase N-terminal domain
IOBKPLHJ_00630 2.1e-174 rbsR K helix_turn _helix lactose operon repressor
IOBKPLHJ_00631 1.1e-193 uhpT EGP Major facilitator Superfamily
IOBKPLHJ_00632 4.7e-309 2.7.7.7 S Domain of unknown function (DUF5060)
IOBKPLHJ_00633 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOBKPLHJ_00634 4.3e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IOBKPLHJ_00635 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IOBKPLHJ_00636 1.2e-188 lacR K Transcriptional regulator
IOBKPLHJ_00637 2.3e-223 L Putative transposase DNA-binding domain
IOBKPLHJ_00638 0.0 lacS G Transporter
IOBKPLHJ_00639 0.0 lacZ 3.2.1.23 G -beta-galactosidase
IOBKPLHJ_00640 8.8e-113
IOBKPLHJ_00641 2.3e-187 M domain protein
IOBKPLHJ_00642 1.1e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOBKPLHJ_00643 4.3e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IOBKPLHJ_00644 7.9e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IOBKPLHJ_00645 1.8e-167 S SLAP domain
IOBKPLHJ_00646 1.1e-39 C FMN binding
IOBKPLHJ_00648 1.2e-45
IOBKPLHJ_00649 5.3e-52 S Domain of unknown function (DUF4160)
IOBKPLHJ_00650 1.1e-96 S Domain of unknown function (DUF4811)
IOBKPLHJ_00651 1.6e-266 lmrB EGP Major facilitator Superfamily
IOBKPLHJ_00652 5e-75 merR K MerR HTH family regulatory protein
IOBKPLHJ_00653 3.7e-159 msmR K helix_turn_helix, arabinose operon control protein
IOBKPLHJ_00654 4e-242 msmE G Bacterial extracellular solute-binding protein
IOBKPLHJ_00655 1.5e-155 msmF P Binding-protein-dependent transport system inner membrane component
IOBKPLHJ_00656 1.5e-152 msmG P Binding-protein-dependent transport system inner membrane component
IOBKPLHJ_00657 2.3e-209 msmX P Belongs to the ABC transporter superfamily
IOBKPLHJ_00658 0.0 rafA 3.2.1.22 G alpha-galactosidase
IOBKPLHJ_00659 1.6e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
IOBKPLHJ_00660 5.6e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOBKPLHJ_00661 2.1e-61 dhaM 2.7.1.121 S PTS system fructose IIA component
IOBKPLHJ_00662 1.2e-103 dhaL 2.7.1.121 S Dak2
IOBKPLHJ_00663 2.3e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IOBKPLHJ_00664 1.7e-113 2.7.6.5 T Region found in RelA / SpoT proteins
IOBKPLHJ_00665 1.5e-118 K response regulator
IOBKPLHJ_00666 1.2e-233 sptS 2.7.13.3 T Histidine kinase
IOBKPLHJ_00667 1.8e-212 EGP Major facilitator Superfamily
IOBKPLHJ_00668 9.2e-71 O OsmC-like protein
IOBKPLHJ_00669 9e-127 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
IOBKPLHJ_00670 2.4e-128
IOBKPLHJ_00672 2.4e-127 S Alpha beta hydrolase
IOBKPLHJ_00673 1.1e-278 yjeM E Amino Acid
IOBKPLHJ_00674 2.9e-13
IOBKPLHJ_00675 4e-109 pncA Q Isochorismatase family
IOBKPLHJ_00676 6e-27 C pentaerythritol trinitrate reductase activity
IOBKPLHJ_00677 9.3e-214 L TIGRFAM transposase, IS605 OrfB family
IOBKPLHJ_00678 8.1e-09 L Probable transposase
IOBKPLHJ_00679 5.7e-177 C Oxidoreductase
IOBKPLHJ_00680 1e-90
IOBKPLHJ_00681 1.5e-244 pgaC GT2 M Glycosyl transferase
IOBKPLHJ_00682 3.6e-143 T EAL domain
IOBKPLHJ_00683 1e-130 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
IOBKPLHJ_00684 2e-208 2.7.7.65 T GGDEF domain
IOBKPLHJ_00687 0.0 1.3.5.4 C FMN_bind
IOBKPLHJ_00688 3.4e-160 K Bacterial regulatory helix-turn-helix protein, lysR family
IOBKPLHJ_00690 1.1e-118 S GyrI-like small molecule binding domain
IOBKPLHJ_00691 2.6e-64 S ASCH domain
IOBKPLHJ_00692 1.7e-57 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOBKPLHJ_00693 1.5e-115 ylbE GM NAD(P)H-binding
IOBKPLHJ_00694 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IOBKPLHJ_00695 3.9e-62 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
IOBKPLHJ_00696 9.1e-264 npr 1.11.1.1 C NADH oxidase
IOBKPLHJ_00698 0.0 oppA E ABC transporter substrate-binding protein
IOBKPLHJ_00699 5.7e-52 S Iron-sulfur cluster assembly protein
IOBKPLHJ_00700 9e-156 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IOBKPLHJ_00701 8.1e-125 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IOBKPLHJ_00702 8.8e-47
IOBKPLHJ_00703 1.5e-147 metQ2 P Belongs to the nlpA lipoprotein family
IOBKPLHJ_00704 1e-50
IOBKPLHJ_00705 8.8e-95 wecD K acetyltransferase
IOBKPLHJ_00706 0.0 UW LPXTG-motif cell wall anchor domain protein
IOBKPLHJ_00707 5.2e-103 O Matrixin
IOBKPLHJ_00708 1.8e-248 clcA P chloride
IOBKPLHJ_00709 0.0 3.6.3.8 P P-type ATPase
IOBKPLHJ_00710 1.3e-35 GM NmrA-like family
IOBKPLHJ_00711 1.5e-67 GM NmrA-like family
IOBKPLHJ_00712 6.4e-119 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOBKPLHJ_00713 1.5e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOBKPLHJ_00714 9.8e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOBKPLHJ_00715 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOBKPLHJ_00716 8.5e-184 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IOBKPLHJ_00717 6.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOBKPLHJ_00718 7.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOBKPLHJ_00719 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IOBKPLHJ_00721 0.0
IOBKPLHJ_00722 2.5e-150 glcU U sugar transport
IOBKPLHJ_00723 4.9e-47
IOBKPLHJ_00724 8.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IOBKPLHJ_00725 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IOBKPLHJ_00726 2.3e-47 S Motility quorum-sensing regulator, toxin of MqsA
IOBKPLHJ_00727 4.2e-65 ps301 K sequence-specific DNA binding
IOBKPLHJ_00728 3.4e-16
IOBKPLHJ_00729 6.4e-100 S Bacterial PH domain
IOBKPLHJ_00730 1.8e-237 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBKPLHJ_00731 7.3e-206 xylR GK ROK family
IOBKPLHJ_00732 1.1e-166 bglK 2.7.1.2, 2.7.1.85 GK ROK family
IOBKPLHJ_00733 7.7e-309 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBKPLHJ_00734 0.0 yic1 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
IOBKPLHJ_00735 0.0 lacA 3.2.1.23 G -beta-galactosidase
IOBKPLHJ_00736 9.6e-254
IOBKPLHJ_00737 1.6e-151 S haloacid dehalogenase-like hydrolase
IOBKPLHJ_00738 8.5e-290 V ABC-type multidrug transport system, ATPase and permease components
IOBKPLHJ_00739 5.2e-295 V ABC-type multidrug transport system, ATPase and permease components
IOBKPLHJ_00740 1e-65 arsC 1.20.4.1 P Belongs to the ArsC family
IOBKPLHJ_00741 6.5e-178 I Carboxylesterase family
IOBKPLHJ_00742 5e-165 S Membrane
IOBKPLHJ_00744 2e-185 M Glycosyl hydrolases family 25
IOBKPLHJ_00745 3.6e-154 cinI S Serine hydrolase (FSH1)
IOBKPLHJ_00746 5e-311 S Predicted membrane protein (DUF2207)
IOBKPLHJ_00747 3.7e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
IOBKPLHJ_00748 9.2e-98 E ABC transporter
IOBKPLHJ_00749 6.7e-60 oppA E ABC transporter
IOBKPLHJ_00751 3.2e-109 Q Imidazolonepropionase and related amidohydrolases
IOBKPLHJ_00752 1.3e-105 Q Imidazolonepropionase and related amidohydrolases
IOBKPLHJ_00753 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IOBKPLHJ_00754 1.8e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IOBKPLHJ_00755 6.8e-259 S Uncharacterized protein conserved in bacteria (DUF2325)
IOBKPLHJ_00756 2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOBKPLHJ_00757 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IOBKPLHJ_00758 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IOBKPLHJ_00759 3.2e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOBKPLHJ_00760 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOBKPLHJ_00761 6.8e-72 yqhY S Asp23 family, cell envelope-related function
IOBKPLHJ_00762 3.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOBKPLHJ_00763 1.9e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOBKPLHJ_00764 7.3e-213 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOBKPLHJ_00765 3.4e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOBKPLHJ_00766 6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOBKPLHJ_00767 3.5e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IOBKPLHJ_00768 4.7e-310 recN L May be involved in recombinational repair of damaged DNA
IOBKPLHJ_00769 1.8e-80 6.3.3.2 S ASCH
IOBKPLHJ_00770 1.5e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
IOBKPLHJ_00771 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOBKPLHJ_00772 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOBKPLHJ_00773 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOBKPLHJ_00774 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOBKPLHJ_00775 2.3e-139 stp 3.1.3.16 T phosphatase
IOBKPLHJ_00776 0.0 KLT serine threonine protein kinase
IOBKPLHJ_00777 8e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOBKPLHJ_00778 4.5e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IOBKPLHJ_00779 6.9e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
IOBKPLHJ_00780 4.2e-52
IOBKPLHJ_00781 3.7e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IOBKPLHJ_00782 6.8e-57 asp S Asp23 family, cell envelope-related function
IOBKPLHJ_00783 2.4e-306 yloV S DAK2 domain fusion protein YloV
IOBKPLHJ_00784 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOBKPLHJ_00785 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOBKPLHJ_00786 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOBKPLHJ_00787 2.5e-197 oppD P Belongs to the ABC transporter superfamily
IOBKPLHJ_00788 6.1e-177 oppF P Belongs to the ABC transporter superfamily
IOBKPLHJ_00789 2.3e-176 oppB P ABC transporter permease
IOBKPLHJ_00790 2.9e-144 oppC P Binding-protein-dependent transport system inner membrane component
IOBKPLHJ_00791 8.8e-167 oppA E ABC transporter substrate-binding protein
IOBKPLHJ_00792 3.2e-152 oppA E ABC transporter substrate-binding protein
IOBKPLHJ_00793 0.0 oppA E ABC transporter substrate-binding protein
IOBKPLHJ_00794 1.2e-263 L COG2963 Transposase and inactivated derivatives
IOBKPLHJ_00795 3.8e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOBKPLHJ_00796 0.0 smc D Required for chromosome condensation and partitioning
IOBKPLHJ_00797 2.1e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOBKPLHJ_00798 2.5e-288 pipD E Dipeptidase
IOBKPLHJ_00799 2.8e-67
IOBKPLHJ_00800 7.8e-258 yfnA E amino acid
IOBKPLHJ_00801 1.6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOBKPLHJ_00802 2.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOBKPLHJ_00803 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IOBKPLHJ_00804 4.7e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOBKPLHJ_00805 5e-128 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IOBKPLHJ_00806 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOBKPLHJ_00807 3.7e-70 2.4.1.83 GT2 S GtrA-like protein
IOBKPLHJ_00808 0.0 S Bacterial membrane protein, YfhO
IOBKPLHJ_00809 3.4e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IOBKPLHJ_00810 3.7e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
IOBKPLHJ_00811 3.1e-144 E GDSL-like Lipase/Acylhydrolase family
IOBKPLHJ_00812 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOBKPLHJ_00813 1.1e-37 ynzC S UPF0291 protein
IOBKPLHJ_00814 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
IOBKPLHJ_00815 0.0 mdlA V ABC transporter
IOBKPLHJ_00816 1.1e-288 mdlB V ABC transporter
IOBKPLHJ_00817 0.0 pepO 3.4.24.71 O Peptidase family M13
IOBKPLHJ_00818 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IOBKPLHJ_00819 6.4e-116 plsC 2.3.1.51 I Acyltransferase
IOBKPLHJ_00820 1.3e-198 yabB 2.1.1.223 L Methyltransferase small domain
IOBKPLHJ_00821 1.1e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
IOBKPLHJ_00822 2.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOBKPLHJ_00823 1.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IOBKPLHJ_00824 8.7e-88 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOBKPLHJ_00825 9.3e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOBKPLHJ_00826 1.7e-145 cdsA 2.7.7.41 I Belongs to the CDS family
IOBKPLHJ_00827 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IOBKPLHJ_00828 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOBKPLHJ_00829 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOBKPLHJ_00830 7.2e-83 rimP J Required for maturation of 30S ribosomal subunits
IOBKPLHJ_00831 3.3e-198 nusA K Participates in both transcription termination and antitermination
IOBKPLHJ_00832 1.4e-47 ylxR K Protein of unknown function (DUF448)
IOBKPLHJ_00833 8.4e-48 rplGA J ribosomal protein
IOBKPLHJ_00834 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOBKPLHJ_00835 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOBKPLHJ_00836 1e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOBKPLHJ_00837 5.2e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IOBKPLHJ_00838 5.5e-264 lsa S ABC transporter
IOBKPLHJ_00839 1.7e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOBKPLHJ_00840 1.9e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOBKPLHJ_00841 0.0 dnaK O Heat shock 70 kDa protein
IOBKPLHJ_00842 7.8e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOBKPLHJ_00843 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOBKPLHJ_00844 4.8e-120 srtA 3.4.22.70 M sortase family
IOBKPLHJ_00845 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IOBKPLHJ_00846 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOBKPLHJ_00847 2.9e-78 K Acetyltransferase (GNAT) domain
IOBKPLHJ_00849 4.7e-151 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IOBKPLHJ_00850 1.1e-211 S Bacterial protein of unknown function (DUF871)
IOBKPLHJ_00851 1.6e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOBKPLHJ_00852 3.7e-119 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IOBKPLHJ_00853 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOBKPLHJ_00854 1.8e-87 3.4.21.96 S SLAP domain
IOBKPLHJ_00855 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
IOBKPLHJ_00856 1.5e-155 lysR5 K LysR substrate binding domain
IOBKPLHJ_00857 4.8e-99 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IOBKPLHJ_00858 2e-140 S Sterol carrier protein domain
IOBKPLHJ_00859 6.3e-72 S Sterol carrier protein domain
IOBKPLHJ_00860 3.7e-15
IOBKPLHJ_00861 2.2e-108 K LysR substrate binding domain
IOBKPLHJ_00862 1.3e-99
IOBKPLHJ_00863 1.1e-121 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
IOBKPLHJ_00864 1.4e-256
IOBKPLHJ_00865 6.4e-201 brnQ U Component of the transport system for branched-chain amino acids
IOBKPLHJ_00866 4.5e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IOBKPLHJ_00867 2e-10
IOBKPLHJ_00868 0.0
IOBKPLHJ_00869 4.1e-21
IOBKPLHJ_00870 2.8e-103 lacA 2.3.1.79 S Transferase hexapeptide repeat
IOBKPLHJ_00871 1.1e-18 yjgN S Bacterial protein of unknown function (DUF898)
IOBKPLHJ_00872 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
IOBKPLHJ_00873 9.4e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
IOBKPLHJ_00874 6.4e-287 thrC 4.2.3.1 E Threonine synthase
IOBKPLHJ_00875 1.3e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IOBKPLHJ_00876 7e-161 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOBKPLHJ_00877 4.8e-122
IOBKPLHJ_00878 2.2e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOBKPLHJ_00879 2.8e-110 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOBKPLHJ_00880 1.3e-95 S Peptidase family M23
IOBKPLHJ_00881 3.4e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOBKPLHJ_00882 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IOBKPLHJ_00883 6.5e-70 yqeY S YqeY-like protein
IOBKPLHJ_00884 1.9e-175 phoH T phosphate starvation-inducible protein PhoH
IOBKPLHJ_00885 7.9e-99 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOBKPLHJ_00886 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOBKPLHJ_00887 1.7e-134 recO L Involved in DNA repair and RecF pathway recombination
IOBKPLHJ_00888 2.5e-177 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IOBKPLHJ_00889 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IOBKPLHJ_00890 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOBKPLHJ_00891 1.4e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOBKPLHJ_00892 4.8e-125 S Peptidase family M23
IOBKPLHJ_00893 5.6e-82 mutT 3.6.1.55 F NUDIX domain
IOBKPLHJ_00894 1.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
IOBKPLHJ_00895 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOBKPLHJ_00896 1.3e-245 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOBKPLHJ_00897 8e-61 yvoA_1 K Transcriptional regulator, GntR family
IOBKPLHJ_00898 1.1e-122 skfE V ATPases associated with a variety of cellular activities
IOBKPLHJ_00899 3.9e-132
IOBKPLHJ_00900 4e-145
IOBKPLHJ_00901 6.8e-131
IOBKPLHJ_00902 2.2e-27
IOBKPLHJ_00903 8.9e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOBKPLHJ_00904 4.1e-141
IOBKPLHJ_00905 3.8e-179
IOBKPLHJ_00906 1.1e-267 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
IOBKPLHJ_00907 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
IOBKPLHJ_00908 4.8e-54 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
IOBKPLHJ_00909 1.3e-107 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
IOBKPLHJ_00910 5.2e-145 K SIS domain
IOBKPLHJ_00911 4.2e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOBKPLHJ_00912 8.4e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IOBKPLHJ_00913 4.1e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IOBKPLHJ_00914 6.6e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
IOBKPLHJ_00915 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IOBKPLHJ_00916 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IOBKPLHJ_00917 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IOBKPLHJ_00918 1.4e-89 ypmB S Protein conserved in bacteria
IOBKPLHJ_00919 2.4e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IOBKPLHJ_00920 5.7e-115 dnaD L DnaD domain protein
IOBKPLHJ_00921 1.5e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOBKPLHJ_00922 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IOBKPLHJ_00923 7.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOBKPLHJ_00924 9.4e-106 ypsA S Belongs to the UPF0398 family
IOBKPLHJ_00925 6.7e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOBKPLHJ_00926 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IOBKPLHJ_00927 7.2e-244 cpdA S Calcineurin-like phosphoesterase
IOBKPLHJ_00928 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IOBKPLHJ_00929 3.6e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOBKPLHJ_00930 3.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOBKPLHJ_00931 3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOBKPLHJ_00932 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
IOBKPLHJ_00933 0.0 FbpA K Fibronectin-binding protein
IOBKPLHJ_00934 9e-66
IOBKPLHJ_00935 3.9e-159 degV S EDD domain protein, DegV family
IOBKPLHJ_00936 8.4e-196 xerS L Belongs to the 'phage' integrase family
IOBKPLHJ_00937 3.1e-59
IOBKPLHJ_00938 1.5e-91 adk 2.7.4.3 F topology modulation protein
IOBKPLHJ_00939 2.4e-107 XK27_00160 S Domain of unknown function (DUF5052)
IOBKPLHJ_00940 4.3e-200 M Glycosyl hydrolases family 25
IOBKPLHJ_00942 3.3e-58 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOBKPLHJ_00943 3.9e-84 K transcriptional
IOBKPLHJ_00944 1e-213 EGP Transmembrane secretion effector
IOBKPLHJ_00945 2.3e-287 V ABC-type multidrug transport system, ATPase and permease components
IOBKPLHJ_00946 2.2e-285 V ABC-type multidrug transport system, ATPase and permease components
IOBKPLHJ_00948 8.2e-66 fic D Fic/DOC family
IOBKPLHJ_00949 1.1e-127 yoaK S Protein of unknown function (DUF1275)
IOBKPLHJ_00950 1.2e-39 K Helix-turn-helix domain
IOBKPLHJ_00951 1.7e-113 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOBKPLHJ_00952 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
IOBKPLHJ_00953 7.8e-185 K Transcriptional regulator
IOBKPLHJ_00954 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOBKPLHJ_00955 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOBKPLHJ_00956 1.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOBKPLHJ_00957 7e-101
IOBKPLHJ_00958 1.9e-168 MA20_14895 S Conserved hypothetical protein 698
IOBKPLHJ_00959 2.2e-18 magIII L Base excision DNA repair protein, HhH-GPD family
IOBKPLHJ_00960 9.2e-17 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOBKPLHJ_00961 5e-44 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOBKPLHJ_00962 1.3e-12 S Alpha beta hydrolase
IOBKPLHJ_00963 3e-251 yagE E amino acid
IOBKPLHJ_00965 3.3e-77 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IOBKPLHJ_00966 2.6e-149 P FAD-binding domain
IOBKPLHJ_00967 2.3e-14 C Flavodoxin
IOBKPLHJ_00968 8.6e-96 S LexA-binding, inner membrane-associated putative hydrolase
IOBKPLHJ_00969 4.2e-141 fldA C Flavodoxin
IOBKPLHJ_00970 4.1e-23
IOBKPLHJ_00971 2.4e-261 gor 1.8.1.7 C Glutathione reductase
IOBKPLHJ_00972 7.7e-100 P esterase
IOBKPLHJ_00973 2.7e-98 fldA C Flavodoxin
IOBKPLHJ_00975 1e-20 C Flavodoxin
IOBKPLHJ_00976 3.6e-146 glcU U ribose uptake protein RbsU
IOBKPLHJ_00977 2.9e-60 C aldo keto reductase
IOBKPLHJ_00978 7.2e-115 tas C Aldo/keto reductase family
IOBKPLHJ_00979 7.1e-55 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IOBKPLHJ_00980 2.6e-146 IQ reductase
IOBKPLHJ_00981 3.1e-83 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
IOBKPLHJ_00982 3.5e-174 yobV1 K WYL domain
IOBKPLHJ_00983 0.0
IOBKPLHJ_00984 0.0
IOBKPLHJ_00985 0.0 ppc 4.1.1.31 C phosphoenolpyruvate carboxylase activity
IOBKPLHJ_00986 2.2e-148 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IOBKPLHJ_00987 2.4e-40 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IOBKPLHJ_00988 4.4e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOBKPLHJ_00989 1.8e-240 steT E amino acid
IOBKPLHJ_00990 4.3e-115 ywnB S NAD(P)H-binding
IOBKPLHJ_00991 3.3e-155 F DNA/RNA non-specific endonuclease
IOBKPLHJ_00992 7.9e-67 L nuclease
IOBKPLHJ_00993 2.3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOBKPLHJ_00994 4.7e-218 2.1.1.14 E methionine synthase, vitamin-B12 independent
IOBKPLHJ_00995 7.7e-114 S L,D-transpeptidase catalytic domain
IOBKPLHJ_00996 2.9e-195 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOBKPLHJ_00997 4.4e-244 yrvN L AAA C-terminal domain
IOBKPLHJ_00998 1.9e-101 ltrA S Bacterial low temperature requirement A protein (LtrA)
IOBKPLHJ_00999 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IOBKPLHJ_01000 1.8e-167 mleR K LysR family
IOBKPLHJ_01001 1.3e-38
IOBKPLHJ_01002 1.5e-91
IOBKPLHJ_01003 8.3e-53 mleP S Sodium Bile acid symporter family
IOBKPLHJ_01004 7.2e-36
IOBKPLHJ_01005 1.4e-112 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOBKPLHJ_01006 7.6e-143 2.4.2.3 F Phosphorylase superfamily
IOBKPLHJ_01007 5.1e-147 2.4.2.3 F Phosphorylase superfamily
IOBKPLHJ_01008 6.2e-108 5.4.2.11 G Phosphoglycerate mutase family
IOBKPLHJ_01009 1.5e-146 2.4.2.3 F Phosphorylase superfamily
IOBKPLHJ_01010 1.3e-71
IOBKPLHJ_01011 9.7e-101
IOBKPLHJ_01012 1.1e-101 S Alpha/beta hydrolase family
IOBKPLHJ_01013 3.7e-93 rimL J Acetyltransferase (GNAT) domain
IOBKPLHJ_01014 1.1e-62
IOBKPLHJ_01015 3.6e-87 FG HIT domain
IOBKPLHJ_01016 1.3e-76
IOBKPLHJ_01017 8.2e-119 3.6.1.55 F NUDIX domain
IOBKPLHJ_01018 1e-153 K Bacterial regulatory helix-turn-helix protein, lysR family
IOBKPLHJ_01019 1.5e-214 ynfM EGP Major facilitator Superfamily
IOBKPLHJ_01020 1.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
IOBKPLHJ_01021 4.9e-108
IOBKPLHJ_01022 2.5e-109
IOBKPLHJ_01023 1.1e-29
IOBKPLHJ_01024 3.4e-174 4.1.1.45 S Amidohydrolase
IOBKPLHJ_01025 8.7e-110 5.4.2.11 G Phosphoglycerate mutase family
IOBKPLHJ_01026 8.3e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOBKPLHJ_01027 2.2e-159 cjaA ET ABC transporter substrate-binding protein
IOBKPLHJ_01028 3.5e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOBKPLHJ_01029 2.2e-77 P ABC transporter permease
IOBKPLHJ_01030 9.3e-113 papP P ABC transporter, permease protein
IOBKPLHJ_01031 4.2e-33 K Transcriptional regulator
IOBKPLHJ_01032 3.9e-170
IOBKPLHJ_01033 3e-164 S reductase
IOBKPLHJ_01034 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
IOBKPLHJ_01035 6.8e-78 K Transcriptional regulator
IOBKPLHJ_01036 6.8e-104
IOBKPLHJ_01039 4.1e-103 yyaR K Acetyltransferase (GNAT) domain
IOBKPLHJ_01040 4.1e-217 S SLAP domain
IOBKPLHJ_01041 2.7e-165 yvgN C Aldo keto reductase
IOBKPLHJ_01042 4.3e-166 akr5f 1.1.1.346 S reductase
IOBKPLHJ_01043 7.7e-168 S Oxidoreductase, aldo keto reductase family protein
IOBKPLHJ_01044 6.6e-159 K Transcriptional regulator
IOBKPLHJ_01045 2.1e-114 ylbE GM NAD dependent epimerase dehydratase family protein
IOBKPLHJ_01046 8.8e-164 rocF 3.5.3.1, 3.5.3.11 E Arginase family
IOBKPLHJ_01047 3.9e-49 K helix_turn_helix, mercury resistance
IOBKPLHJ_01048 5.2e-54 1.6.5.2 GM NmrA-like family
IOBKPLHJ_01049 1.2e-52 S Peptidase propeptide and YPEB domain
IOBKPLHJ_01050 1.6e-194 yniG EGP Major facilitator Superfamily
IOBKPLHJ_01052 1.3e-33
IOBKPLHJ_01053 1.3e-42 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
IOBKPLHJ_01054 6.8e-113 S Hydrolases of the alpha beta superfamily
IOBKPLHJ_01055 2.9e-115 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IOBKPLHJ_01056 1.1e-203 S Uncharacterized protein conserved in bacteria (DUF2252)
IOBKPLHJ_01057 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOBKPLHJ_01058 1.8e-223 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IOBKPLHJ_01059 2.5e-84 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOBKPLHJ_01060 3e-51 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IOBKPLHJ_01061 2.2e-73 C Aldo/keto reductase family
IOBKPLHJ_01062 8e-42 C Aldo/keto reductase family
IOBKPLHJ_01064 4.8e-54 yjaB_1 K Acetyltransferase (GNAT) domain
IOBKPLHJ_01065 1.6e-253 S C4-dicarboxylate anaerobic carrier
IOBKPLHJ_01066 5e-143
IOBKPLHJ_01067 1.7e-124 S Sucrose-6F-phosphate phosphohydrolase
IOBKPLHJ_01068 0.0 UW LPXTG-motif cell wall anchor domain protein
IOBKPLHJ_01069 1.3e-180 M NlpC/P60 family
IOBKPLHJ_01070 2.6e-126 G Peptidase_C39 like family
IOBKPLHJ_01071 1.4e-199 amd 3.5.1.47 E Peptidase family M20/M25/M40
IOBKPLHJ_01073 3e-262 N Uncharacterized conserved protein (DUF2075)
IOBKPLHJ_01074 8e-87
IOBKPLHJ_01075 7.3e-34
IOBKPLHJ_01076 6.4e-51 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IOBKPLHJ_01077 4.6e-60
IOBKPLHJ_01078 0.0 rafA 3.2.1.22 G alpha-galactosidase
IOBKPLHJ_01079 3e-239 scrB 2.7.1.211, 3.2.1.26 GH32 G Glycosyl hydrolases family 32
IOBKPLHJ_01080 8.5e-260 sacP 2.7.1.211 G phosphotransferase system, EIIB
IOBKPLHJ_01081 1.4e-134 K AraC-like ligand binding domain
IOBKPLHJ_01082 0.0 UW LPXTG-motif cell wall anchor domain protein
IOBKPLHJ_01083 0.0 UW LPXTG-motif cell wall anchor domain protein
IOBKPLHJ_01084 2.6e-21 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
IOBKPLHJ_01085 2.4e-164 M domain protein
IOBKPLHJ_01086 3.8e-99 UW LPXTG-motif cell wall anchor domain protein
IOBKPLHJ_01087 2.8e-128 M Glycosyl transferases group 1
IOBKPLHJ_01088 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IOBKPLHJ_01089 2.9e-128 treR K UTRA
IOBKPLHJ_01090 0.0 treB 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOBKPLHJ_01091 6.5e-241
IOBKPLHJ_01092 2.1e-216 S Putative peptidoglycan binding domain
IOBKPLHJ_01093 3.1e-93 S ECF-type riboflavin transporter, S component
IOBKPLHJ_01094 1.5e-155 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IOBKPLHJ_01095 1.9e-208 pbpX1 V Beta-lactamase
IOBKPLHJ_01096 4.5e-67 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOBKPLHJ_01097 1.8e-113 3.6.1.27 I Acid phosphatase homologues
IOBKPLHJ_01098 5.9e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IOBKPLHJ_01099 0.0 uvrA3 L excinuclease ABC, A subunit
IOBKPLHJ_01100 4.9e-81 C Flavodoxin
IOBKPLHJ_01101 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IOBKPLHJ_01102 4e-240 ktrB P Potassium uptake protein
IOBKPLHJ_01103 3.9e-119 ktrA P domain protein
IOBKPLHJ_01104 3.2e-247 ynbB 4.4.1.1 P aluminum resistance
IOBKPLHJ_01105 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
IOBKPLHJ_01106 5.3e-286 E Amino acid permease
IOBKPLHJ_01107 6.9e-275 pepV 3.5.1.18 E dipeptidase PepV
IOBKPLHJ_01108 1.1e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOBKPLHJ_01109 3.5e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOBKPLHJ_01110 1.4e-150 xerD L Phage integrase, N-terminal SAM-like domain
IOBKPLHJ_01111 3.2e-158 S Alpha/beta hydrolase of unknown function (DUF915)
IOBKPLHJ_01112 3.8e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBKPLHJ_01113 2.4e-27
IOBKPLHJ_01114 2.8e-24
IOBKPLHJ_01115 1.8e-180 lacX 5.1.3.3 G Aldose 1-epimerase
IOBKPLHJ_01116 4.4e-135 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOBKPLHJ_01117 6.1e-73 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOBKPLHJ_01118 1.1e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOBKPLHJ_01119 7.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
IOBKPLHJ_01120 6.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOBKPLHJ_01121 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOBKPLHJ_01122 3.6e-157 dprA LU DNA protecting protein DprA
IOBKPLHJ_01123 5.4e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOBKPLHJ_01124 1e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOBKPLHJ_01125 3.5e-283 yjcE P Sodium proton antiporter
IOBKPLHJ_01126 2.7e-35 yozE S Belongs to the UPF0346 family
IOBKPLHJ_01127 5.1e-15 DegV S Uncharacterised protein, DegV family COG1307
IOBKPLHJ_01128 7.2e-110 DegV S Uncharacterised protein, DegV family COG1307
IOBKPLHJ_01129 2.2e-106 hlyIII S protein, hemolysin III
IOBKPLHJ_01130 1.2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOBKPLHJ_01131 1.3e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOBKPLHJ_01132 2.1e-230 S Tetratricopeptide repeat protein
IOBKPLHJ_01133 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOBKPLHJ_01134 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IOBKPLHJ_01135 2.3e-202 rpsA 1.17.7.4 J Ribosomal protein S1
IOBKPLHJ_01136 8.4e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IOBKPLHJ_01137 1.1e-46 M Lysin motif
IOBKPLHJ_01138 4.4e-92 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOBKPLHJ_01139 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOBKPLHJ_01140 3.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOBKPLHJ_01141 1.3e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOBKPLHJ_01142 1.7e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOBKPLHJ_01143 1.6e-168 xerD D recombinase XerD
IOBKPLHJ_01144 5e-170 cvfB S S1 domain
IOBKPLHJ_01145 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IOBKPLHJ_01146 7.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOBKPLHJ_01147 0.0 dnaE 2.7.7.7 L DNA polymerase
IOBKPLHJ_01149 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IOBKPLHJ_01150 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IOBKPLHJ_01151 5.1e-32 yrvD S Lipopolysaccharide assembly protein A domain
IOBKPLHJ_01152 7.2e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOBKPLHJ_01153 2.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOBKPLHJ_01154 2e-91 I Acyltransferase
IOBKPLHJ_01155 3.3e-213 I Acyltransferase
IOBKPLHJ_01156 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOBKPLHJ_01157 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOBKPLHJ_01158 2.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
IOBKPLHJ_01159 3.9e-230 yfnA E Amino Acid
IOBKPLHJ_01160 3.1e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOBKPLHJ_01161 1.6e-151 yxeH S hydrolase
IOBKPLHJ_01162 3.5e-154 S reductase
IOBKPLHJ_01163 2.8e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOBKPLHJ_01164 2.5e-225 patA 2.6.1.1 E Aminotransferase
IOBKPLHJ_01165 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IOBKPLHJ_01166 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IOBKPLHJ_01167 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOBKPLHJ_01168 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOBKPLHJ_01169 4e-49
IOBKPLHJ_01170 2.1e-174 prmA J Ribosomal protein L11 methyltransferase
IOBKPLHJ_01171 1.5e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOBKPLHJ_01172 5.5e-245 yjjP S Putative threonine/serine exporter
IOBKPLHJ_01173 1.2e-177 citR K Putative sugar-binding domain
IOBKPLHJ_01174 2.2e-54
IOBKPLHJ_01175 1.3e-63 S Domain of unknown function DUF1828
IOBKPLHJ_01176 7.4e-95 S UPF0397 protein
IOBKPLHJ_01177 0.0 ykoD P ABC transporter, ATP-binding protein
IOBKPLHJ_01178 3.8e-148 cbiQ P cobalt transport
IOBKPLHJ_01179 3.3e-13
IOBKPLHJ_01180 9.3e-72 yeaL S Protein of unknown function (DUF441)
IOBKPLHJ_01181 3.5e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IOBKPLHJ_01182 1.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IOBKPLHJ_01183 4.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
IOBKPLHJ_01184 8.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IOBKPLHJ_01185 1.1e-155 ydjP I Alpha/beta hydrolase family
IOBKPLHJ_01186 1.2e-274 P Sodium:sulfate symporter transmembrane region
IOBKPLHJ_01187 1.2e-257 pepC 3.4.22.40 E Peptidase C1-like family
IOBKPLHJ_01188 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOBKPLHJ_01189 8e-293 M domain protein
IOBKPLHJ_01190 2e-266 frdC 1.3.5.4 C FAD binding domain
IOBKPLHJ_01191 2e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOBKPLHJ_01192 4.9e-80 metI P ABC transporter permease
IOBKPLHJ_01193 2.2e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOBKPLHJ_01194 5e-159 metQ1 P Belongs to the nlpA lipoprotein family
IOBKPLHJ_01195 0.0 aha1 P E1-E2 ATPase
IOBKPLHJ_01196 6.2e-93 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOBKPLHJ_01197 6.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOBKPLHJ_01198 8.1e-252 yifK E Amino acid permease
IOBKPLHJ_01199 4.4e-29 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IOBKPLHJ_01200 1.2e-55 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
IOBKPLHJ_01202 2.9e-82
IOBKPLHJ_01203 2.4e-11
IOBKPLHJ_01204 4.3e-180 L Belongs to the 'phage' integrase family
IOBKPLHJ_01206 8.7e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOBKPLHJ_01207 1.7e-99 3.6.1.27 I Acid phosphatase homologues
IOBKPLHJ_01208 6.8e-153 yitS S Uncharacterised protein, DegV family COG1307
IOBKPLHJ_01209 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOBKPLHJ_01210 1.3e-108 S Domain of unknown function (DUF4767)
IOBKPLHJ_01211 1.6e-85 C Nitroreductase family
IOBKPLHJ_01212 6.8e-156 ypbG 2.7.1.2 GK ROK family
IOBKPLHJ_01213 9.5e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBKPLHJ_01214 6.2e-241 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBKPLHJ_01217 2.7e-10
IOBKPLHJ_01218 8.5e-145
IOBKPLHJ_01219 2.7e-16 adhC 1.1.1.90 C S-(hydroxymethyl)glutathione dehydrogenase activity
IOBKPLHJ_01220 1.3e-37 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
IOBKPLHJ_01221 3.3e-129 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
IOBKPLHJ_01222 1.9e-286
IOBKPLHJ_01223 1.6e-80
IOBKPLHJ_01224 8.6e-41 C FMN_bind
IOBKPLHJ_01225 1.3e-298 I Protein of unknown function (DUF2974)
IOBKPLHJ_01226 3.9e-204 pbpX1 V Beta-lactamase
IOBKPLHJ_01227 5.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOBKPLHJ_01228 5.3e-220 aspC 2.6.1.1 E Aminotransferase
IOBKPLHJ_01229 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOBKPLHJ_01230 1.9e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOBKPLHJ_01231 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOBKPLHJ_01232 5.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOBKPLHJ_01233 2.9e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOBKPLHJ_01234 2.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
IOBKPLHJ_01235 8.9e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOBKPLHJ_01236 2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
IOBKPLHJ_01237 1.2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOBKPLHJ_01238 3.3e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOBKPLHJ_01239 1.2e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOBKPLHJ_01240 2.2e-151
IOBKPLHJ_01241 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOBKPLHJ_01242 1.1e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOBKPLHJ_01243 3e-35 rpsT J Binds directly to 16S ribosomal RNA
IOBKPLHJ_01244 8.8e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
IOBKPLHJ_01245 0.0 comEC S Competence protein ComEC
IOBKPLHJ_01246 1.7e-72 comEA L Competence protein ComEA
IOBKPLHJ_01247 7.6e-194 ylbL T Belongs to the peptidase S16 family
IOBKPLHJ_01248 6.2e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOBKPLHJ_01249 4.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IOBKPLHJ_01250 4.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IOBKPLHJ_01251 4.7e-211 ftsW D Belongs to the SEDS family
IOBKPLHJ_01252 0.0 typA T GTP-binding protein TypA
IOBKPLHJ_01253 1.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOBKPLHJ_01254 3.2e-33 ykzG S Belongs to the UPF0356 family
IOBKPLHJ_01255 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOBKPLHJ_01256 9.3e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IOBKPLHJ_01257 1.2e-288 L Nuclease-related domain
IOBKPLHJ_01258 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOBKPLHJ_01259 5.7e-115 S Repeat protein
IOBKPLHJ_01260 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IOBKPLHJ_01261 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOBKPLHJ_01262 9.8e-58 XK27_04120 S Putative amino acid metabolism
IOBKPLHJ_01263 6.5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOBKPLHJ_01264 3.4e-28
IOBKPLHJ_01265 4.9e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IOBKPLHJ_01266 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
IOBKPLHJ_01267 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOBKPLHJ_01268 1.9e-75 gpsB D DivIVA domain protein
IOBKPLHJ_01269 1.3e-148 ylmH S S4 domain protein
IOBKPLHJ_01270 2.5e-41 yggT S YGGT family
IOBKPLHJ_01271 6.2e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOBKPLHJ_01272 4.2e-245 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOBKPLHJ_01273 2.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOBKPLHJ_01274 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOBKPLHJ_01275 4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOBKPLHJ_01276 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOBKPLHJ_01277 2.1e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOBKPLHJ_01278 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IOBKPLHJ_01279 2.4e-54 ftsL D Cell division protein FtsL
IOBKPLHJ_01280 2.2e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOBKPLHJ_01281 4e-72 mraZ K Belongs to the MraZ family
IOBKPLHJ_01282 3.2e-53 S Protein of unknown function (DUF3397)
IOBKPLHJ_01283 8.8e-10 S Protein of unknown function (DUF4044)
IOBKPLHJ_01284 1.3e-93 mreD
IOBKPLHJ_01285 7.2e-150 mreC M Involved in formation and maintenance of cell shape
IOBKPLHJ_01286 1.1e-176 mreB D cell shape determining protein MreB
IOBKPLHJ_01287 1.2e-114 radC L DNA repair protein
IOBKPLHJ_01288 8.9e-127 S Haloacid dehalogenase-like hydrolase
IOBKPLHJ_01289 8.5e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOBKPLHJ_01290 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOBKPLHJ_01291 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOBKPLHJ_01292 5.9e-230 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOBKPLHJ_01293 1.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
IOBKPLHJ_01294 1.5e-292 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOBKPLHJ_01295 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOBKPLHJ_01296 1.9e-83 yueI S Protein of unknown function (DUF1694)
IOBKPLHJ_01297 4.2e-242 rarA L recombination factor protein RarA
IOBKPLHJ_01298 4e-33
IOBKPLHJ_01299 5.8e-77 uspA T universal stress protein
IOBKPLHJ_01300 9.5e-217 rodA D Belongs to the SEDS family
IOBKPLHJ_01301 1.5e-33 S Protein of unknown function (DUF2969)
IOBKPLHJ_01302 2.5e-49 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IOBKPLHJ_01303 1.9e-178 mbl D Cell shape determining protein MreB Mrl
IOBKPLHJ_01304 2.6e-30 ywzB S Protein of unknown function (DUF1146)
IOBKPLHJ_01305 6.9e-64 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IOBKPLHJ_01306 2.1e-255 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOBKPLHJ_01307 9.8e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOBKPLHJ_01308 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOBKPLHJ_01309 1.5e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOBKPLHJ_01310 1.7e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOBKPLHJ_01311 6.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOBKPLHJ_01312 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
IOBKPLHJ_01313 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOBKPLHJ_01314 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOBKPLHJ_01315 7.8e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOBKPLHJ_01316 3.4e-181 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOBKPLHJ_01317 4.5e-114 tdk 2.7.1.21 F thymidine kinase
IOBKPLHJ_01318 2e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IOBKPLHJ_01319 5.8e-219 sip L Belongs to the 'phage' integrase family
IOBKPLHJ_01320 3.2e-58 K Transcriptional
IOBKPLHJ_01321 2.9e-12 S Helix-turn-helix domain
IOBKPLHJ_01322 1.4e-36
IOBKPLHJ_01323 8.1e-69
IOBKPLHJ_01324 1.9e-33
IOBKPLHJ_01325 1.6e-35
IOBKPLHJ_01326 2.9e-287 S DNA primase
IOBKPLHJ_01327 2e-64
IOBKPLHJ_01330 1.6e-196 ampC V Beta-lactamase
IOBKPLHJ_01331 9.9e-250 EGP Major facilitator Superfamily
IOBKPLHJ_01332 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
IOBKPLHJ_01333 4.1e-107 vanZ V VanZ like family
IOBKPLHJ_01334 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOBKPLHJ_01335 2.2e-123 XK27_00915 C Luciferase-like monooxygenase
IOBKPLHJ_01336 1.6e-61 limB 1.14.13.107, 1.14.13.162 C Luciferase-like monooxygenase
IOBKPLHJ_01337 6.2e-271 T PhoQ Sensor
IOBKPLHJ_01338 4.4e-42 K Transcriptional regulatory protein, C terminal
IOBKPLHJ_01339 3.3e-71 K Transcriptional regulatory protein, C terminal
IOBKPLHJ_01340 4.9e-61 S SdpI/YhfL protein family
IOBKPLHJ_01341 2.3e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
IOBKPLHJ_01342 5.7e-29 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IOBKPLHJ_01343 8.1e-176 patB 4.4.1.8 E Aminotransferase, class I
IOBKPLHJ_01344 4.3e-121 M Protein of unknown function (DUF3737)
IOBKPLHJ_01346 1.7e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBKPLHJ_01347 3e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
IOBKPLHJ_01348 1.3e-86 comGF U Putative Competence protein ComGF
IOBKPLHJ_01349 1e-19
IOBKPLHJ_01350 2e-71
IOBKPLHJ_01351 2.4e-46 comGC U competence protein ComGC
IOBKPLHJ_01352 9.9e-175 comGB NU type II secretion system
IOBKPLHJ_01353 5.4e-178 comGA NU Type II IV secretion system protein
IOBKPLHJ_01354 2e-132 yebC K Transcriptional regulatory protein
IOBKPLHJ_01355 1.9e-92 S VanZ like family
IOBKPLHJ_01356 2.2e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOBKPLHJ_01358 0.0 E Amino acid permease
IOBKPLHJ_01359 4.2e-175 D Alpha beta
IOBKPLHJ_01360 3.1e-286 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBKPLHJ_01361 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOBKPLHJ_01362 9.9e-152 licT K CAT RNA binding domain
IOBKPLHJ_01363 6.7e-212 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IOBKPLHJ_01364 1.7e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOBKPLHJ_01365 1e-120
IOBKPLHJ_01366 2.9e-145 S Sucrose-6F-phosphate phosphohydrolase
IOBKPLHJ_01367 1.3e-148 S hydrolase
IOBKPLHJ_01368 3.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOBKPLHJ_01369 1.2e-172 ybbR S YbbR-like protein
IOBKPLHJ_01370 1.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOBKPLHJ_01371 1e-206 potD P ABC transporter
IOBKPLHJ_01372 2.9e-132 potC P ABC transporter permease
IOBKPLHJ_01373 1.1e-136 potB P ABC transporter permease
IOBKPLHJ_01374 9.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOBKPLHJ_01375 2.4e-164 murB 1.3.1.98 M Cell wall formation
IOBKPLHJ_01376 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
IOBKPLHJ_01377 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IOBKPLHJ_01378 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IOBKPLHJ_01379 2.6e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOBKPLHJ_01380 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
IOBKPLHJ_01381 1.3e-96
IOBKPLHJ_01382 9.9e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOBKPLHJ_01383 3.5e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IOBKPLHJ_01384 8.4e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOBKPLHJ_01385 8.6e-190 cggR K Putative sugar-binding domain
IOBKPLHJ_01387 1.3e-276 ycaM E amino acid
IOBKPLHJ_01388 0.0 S SH3-like domain
IOBKPLHJ_01389 4.7e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOBKPLHJ_01390 6.8e-170 whiA K May be required for sporulation
IOBKPLHJ_01391 8.1e-196 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IOBKPLHJ_01392 4.8e-165 rapZ S Displays ATPase and GTPase activities
IOBKPLHJ_01393 1.1e-90 S Short repeat of unknown function (DUF308)
IOBKPLHJ_01394 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOBKPLHJ_01395 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOBKPLHJ_01396 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IOBKPLHJ_01397 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
IOBKPLHJ_01398 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOBKPLHJ_01399 2.8e-287 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
IOBKPLHJ_01400 7.2e-214 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
IOBKPLHJ_01401 5.7e-100 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOBKPLHJ_01402 8.6e-107 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOBKPLHJ_01403 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOBKPLHJ_01404 1.2e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOBKPLHJ_01405 6.1e-188 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IOBKPLHJ_01406 1.4e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOBKPLHJ_01407 1.2e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOBKPLHJ_01409 3.5e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOBKPLHJ_01410 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOBKPLHJ_01411 5.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOBKPLHJ_01412 1.2e-117 comFC S Competence protein
IOBKPLHJ_01413 3.3e-247 comFA L Helicase C-terminal domain protein
IOBKPLHJ_01414 9.6e-118 yvyE 3.4.13.9 S YigZ family
IOBKPLHJ_01415 1.8e-212 tagO 2.7.8.33, 2.7.8.35 M transferase
IOBKPLHJ_01416 8.7e-221 rny S Endoribonuclease that initiates mRNA decay
IOBKPLHJ_01417 7.9e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOBKPLHJ_01418 9.3e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOBKPLHJ_01419 6.6e-119 ymfM S Helix-turn-helix domain
IOBKPLHJ_01420 2e-132 IQ Enoyl-(Acyl carrier protein) reductase
IOBKPLHJ_01421 2.2e-240 S Peptidase M16
IOBKPLHJ_01422 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
IOBKPLHJ_01423 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IOBKPLHJ_01424 1.8e-68 WQ51_03320 S Protein of unknown function (DUF1149)
IOBKPLHJ_01425 1.3e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOBKPLHJ_01426 3.2e-212 yubA S AI-2E family transporter
IOBKPLHJ_01427 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IOBKPLHJ_01428 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
IOBKPLHJ_01429 1.7e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IOBKPLHJ_01430 2e-118 S SNARE associated Golgi protein
IOBKPLHJ_01431 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IOBKPLHJ_01432 8.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOBKPLHJ_01433 1e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOBKPLHJ_01434 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
IOBKPLHJ_01435 9.5e-112 yjbK S CYTH
IOBKPLHJ_01436 1.2e-114 yjbH Q Thioredoxin
IOBKPLHJ_01437 1.4e-161 coiA 3.6.4.12 S Competence protein
IOBKPLHJ_01438 8.8e-128 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IOBKPLHJ_01439 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOBKPLHJ_01440 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOBKPLHJ_01441 8.5e-41 ptsH G phosphocarrier protein HPR
IOBKPLHJ_01442 6.6e-200 clpE O Belongs to the ClpA ClpB family
IOBKPLHJ_01443 1.7e-162 clpE O Belongs to the ClpA ClpB family
IOBKPLHJ_01444 6.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
IOBKPLHJ_01445 1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IOBKPLHJ_01446 9.5e-158 hlyX S Transporter associated domain
IOBKPLHJ_01447 1.2e-71
IOBKPLHJ_01448 9.1e-86
IOBKPLHJ_01449 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
IOBKPLHJ_01450 6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOBKPLHJ_01451 1.5e-177 D Alpha beta
IOBKPLHJ_01452 1.9e-46
IOBKPLHJ_01453 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IOBKPLHJ_01454 4.6e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IOBKPLHJ_01455 5.1e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
IOBKPLHJ_01456 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOBKPLHJ_01457 4.1e-151 yihY S Belongs to the UPF0761 family
IOBKPLHJ_01458 1.1e-163 map 3.4.11.18 E Methionine Aminopeptidase
IOBKPLHJ_01459 1.2e-79 fld C Flavodoxin
IOBKPLHJ_01460 4.3e-89 gtcA S Teichoic acid glycosylation protein
IOBKPLHJ_01461 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOBKPLHJ_01463 1.2e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBKPLHJ_01464 2.6e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
IOBKPLHJ_01465 1.1e-130 M Glycosyl hydrolases family 25
IOBKPLHJ_01466 1.5e-228 potE E amino acid
IOBKPLHJ_01467 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOBKPLHJ_01468 1.1e-248 yhdP S Transporter associated domain
IOBKPLHJ_01469 1.6e-120 C nitroreductase
IOBKPLHJ_01470 1.9e-40
IOBKPLHJ_01471 1.1e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOBKPLHJ_01472 5.4e-81
IOBKPLHJ_01473 7.6e-149 glvR K Helix-turn-helix domain, rpiR family
IOBKPLHJ_01474 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
IOBKPLHJ_01475 2.3e-153 S hydrolase
IOBKPLHJ_01476 2.9e-221 S CAAX protease self-immunity
IOBKPLHJ_01477 8.5e-145 K LytTr DNA-binding domain
IOBKPLHJ_01478 3.8e-224 2.7.13.3 T GHKL domain
IOBKPLHJ_01479 4.5e-160 rssA S Phospholipase, patatin family
IOBKPLHJ_01480 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IOBKPLHJ_01481 1.3e-137 glcR K DeoR C terminal sensor domain
IOBKPLHJ_01482 2.1e-58 S Enterocin A Immunity
IOBKPLHJ_01483 0.0 lmrA 3.6.3.44 V ABC transporter
IOBKPLHJ_01484 5.3e-72 K helix_turn_helix multiple antibiotic resistance protein
IOBKPLHJ_01485 1.8e-153 S hydrolase
IOBKPLHJ_01486 2.9e-285 V ABC transporter transmembrane region
IOBKPLHJ_01487 1.2e-112
IOBKPLHJ_01488 2.6e-22
IOBKPLHJ_01489 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
IOBKPLHJ_01490 6.3e-176 rihB 3.2.2.1 F Nucleoside
IOBKPLHJ_01491 0.0 kup P Transport of potassium into the cell
IOBKPLHJ_01492 2e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOBKPLHJ_01493 1.7e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOBKPLHJ_01494 4.1e-163 2.7.7.12 C Domain of unknown function (DUF4931)
IOBKPLHJ_01495 4.8e-238 G Bacterial extracellular solute-binding protein
IOBKPLHJ_01496 1.2e-63
IOBKPLHJ_01497 1.5e-174 S Protein of unknown function (DUF2974)
IOBKPLHJ_01498 1.9e-110 glnP P ABC transporter permease
IOBKPLHJ_01499 6.1e-93 gluC P ABC transporter permease
IOBKPLHJ_01500 1.3e-148 glnH ET ABC transporter substrate-binding protein
IOBKPLHJ_01501 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOBKPLHJ_01502 7.2e-115 udk 2.7.1.48 F Zeta toxin
IOBKPLHJ_01503 2.9e-102 S ABC-type cobalt transport system, permease component
IOBKPLHJ_01504 0.0 V ABC transporter transmembrane region
IOBKPLHJ_01505 7.1e-306 XK27_09600 V ABC transporter, ATP-binding protein
IOBKPLHJ_01506 2.3e-78 K Transcriptional regulator, MarR family
IOBKPLHJ_01507 9e-150 glnH ET ABC transporter
IOBKPLHJ_01508 9.8e-146
IOBKPLHJ_01509 0.0 ybiT S ABC transporter, ATP-binding protein
IOBKPLHJ_01510 2.1e-210 pepA E M42 glutamyl aminopeptidase
IOBKPLHJ_01511 1.8e-165 mleP3 S Membrane transport protein
IOBKPLHJ_01512 4e-215 mdtG EGP Major facilitator Superfamily
IOBKPLHJ_01513 1.6e-253 emrY EGP Major facilitator Superfamily
IOBKPLHJ_01514 2.4e-50 3.1.3.102, 3.1.3.104 Q phosphatase activity
IOBKPLHJ_01515 1.5e-86 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IOBKPLHJ_01516 9.5e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOBKPLHJ_01517 2.1e-241 pyrP F Permease
IOBKPLHJ_01518 4.3e-18 cydD V cysteine transport
IOBKPLHJ_01519 6.1e-100 cydD V cysteine transport
IOBKPLHJ_01520 3.6e-109 V ABC-type multidrug transport system, ATPase and permease components
IOBKPLHJ_01521 8e-162 S reductase
IOBKPLHJ_01522 8.4e-78 2.3.1.128 K acetyltransferase
IOBKPLHJ_01523 0.0 4.2.1.53 S Myosin-crossreactive antigen
IOBKPLHJ_01524 5e-90 yxdD K Bacterial regulatory proteins, tetR family
IOBKPLHJ_01525 6.8e-136 S CAAX protease self-immunity
IOBKPLHJ_01526 3.9e-244 emrY EGP Major facilitator Superfamily
IOBKPLHJ_01531 6.6e-95 MA20_25245 K Acetyltransferase (GNAT) domain
IOBKPLHJ_01532 1.4e-178 L Recombinase zinc beta ribbon domain
IOBKPLHJ_01533 7.8e-94 L Resolvase, N terminal domain
IOBKPLHJ_01534 9e-192 L Recombinase
IOBKPLHJ_01535 6.5e-57 5.1.1.13 M Asp/Glu/Hydantoin racemase
IOBKPLHJ_01536 1.2e-48 5.1.1.13 M Asp/Glu/Hydantoin racemase
IOBKPLHJ_01537 1.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
IOBKPLHJ_01538 8.9e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IOBKPLHJ_01539 5e-96 dps P Belongs to the Dps family
IOBKPLHJ_01540 3.9e-34 copZ C Heavy-metal-associated domain
IOBKPLHJ_01541 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
IOBKPLHJ_01542 1.1e-62
IOBKPLHJ_01543 1.6e-22
IOBKPLHJ_01544 9.6e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOBKPLHJ_01545 1.5e-245 nhaC C Na H antiporter NhaC
IOBKPLHJ_01546 4.1e-56
IOBKPLHJ_01547 2.2e-112 ybhL S Belongs to the BI1 family
IOBKPLHJ_01548 4.2e-172 yegS 2.7.1.107 G Lipid kinase
IOBKPLHJ_01549 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOBKPLHJ_01550 1.5e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOBKPLHJ_01551 2.6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOBKPLHJ_01552 1.1e-201 camS S sex pheromone
IOBKPLHJ_01553 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOBKPLHJ_01554 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IOBKPLHJ_01555 2.8e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
IOBKPLHJ_01557 4.3e-64 ydcK S Belongs to the SprT family
IOBKPLHJ_01558 9.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
IOBKPLHJ_01559 1.1e-256 epsU S Polysaccharide biosynthesis protein
IOBKPLHJ_01560 2.9e-226 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOBKPLHJ_01561 0.0 pacL 3.6.3.8 P P-type ATPase
IOBKPLHJ_01562 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOBKPLHJ_01563 1.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOBKPLHJ_01564 1.1e-206 csaB M Glycosyl transferases group 1
IOBKPLHJ_01565 8e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOBKPLHJ_01566 1.5e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IOBKPLHJ_01567 7.3e-124 gntR1 K UTRA
IOBKPLHJ_01568 4e-209
IOBKPLHJ_01571 3.9e-276 slpX S SLAP domain
IOBKPLHJ_01572 1.3e-177 pfoS S Phosphotransferase system, EIIC
IOBKPLHJ_01574 6.1e-70 EGP Major facilitator Superfamily
IOBKPLHJ_01575 2.6e-285 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
IOBKPLHJ_01576 6.5e-212 msmX P Belongs to the ABC transporter superfamily
IOBKPLHJ_01577 5.8e-260 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
IOBKPLHJ_01578 3.3e-155 msmG G Binding-protein-dependent transport system inner membrane component
IOBKPLHJ_01579 4.5e-163 msmF P ABC-type sugar transport systems, permease components
IOBKPLHJ_01580 2.7e-249 G Bacterial extracellular solute-binding protein
IOBKPLHJ_01581 3.9e-184 msmR K helix_turn _helix lactose operon repressor
IOBKPLHJ_01582 1.2e-29 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOBKPLHJ_01583 5.4e-52 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOBKPLHJ_01584 1e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
IOBKPLHJ_01585 6.6e-107 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
IOBKPLHJ_01586 4.9e-110 5.4.2.11 G Phosphoglycerate mutase family
IOBKPLHJ_01587 4.1e-195 D nuclear chromosome segregation
IOBKPLHJ_01588 7.8e-70 M LysM domain protein
IOBKPLHJ_01589 2.5e-161 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IOBKPLHJ_01590 2.1e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBKPLHJ_01591 5.6e-13
IOBKPLHJ_01592 1.7e-89 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IOBKPLHJ_01593 8.1e-63 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IOBKPLHJ_01594 5.9e-67
IOBKPLHJ_01595 5.1e-33
IOBKPLHJ_01596 1.3e-69 S Iron-sulphur cluster biosynthesis
IOBKPLHJ_01597 1.3e-229 L Belongs to the 'phage' integrase family
IOBKPLHJ_01598 2.8e-12
IOBKPLHJ_01599 7.7e-186 repB EP Plasmid replication protein
IOBKPLHJ_01601 1.9e-211 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOBKPLHJ_01602 6.3e-57
IOBKPLHJ_01604 7.1e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IOBKPLHJ_01605 3.4e-163 dam2 2.1.1.72 L DNA methyltransferase
IOBKPLHJ_01606 6.7e-243 S AAA ATPase domain
IOBKPLHJ_01607 1.6e-38 S AAA ATPase domain
IOBKPLHJ_01608 0.0 L Type III restriction enzyme, res subunit
IOBKPLHJ_01610 6.8e-144 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IOBKPLHJ_01611 7.1e-231 amtB P ammonium transporter
IOBKPLHJ_01612 4.3e-62
IOBKPLHJ_01613 2.2e-37 lhr L DEAD DEAH box helicase
IOBKPLHJ_01614 0.0 lhr L DEAD DEAH box helicase
IOBKPLHJ_01615 1.4e-253 P P-loop Domain of unknown function (DUF2791)
IOBKPLHJ_01616 0.0 S TerB-C domain
IOBKPLHJ_01617 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IOBKPLHJ_01618 2.1e-70 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IOBKPLHJ_01619 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
IOBKPLHJ_01620 4e-110 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBKPLHJ_01621 1.4e-89 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBKPLHJ_01622 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOBKPLHJ_01623 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IOBKPLHJ_01624 9.2e-248 cycA E Amino acid permease
IOBKPLHJ_01625 3.9e-69 S transferase hexapeptide repeat
IOBKPLHJ_01626 3.7e-160 K Transcriptional regulator
IOBKPLHJ_01627 4e-65 manO S Domain of unknown function (DUF956)
IOBKPLHJ_01628 4.1e-175 manN G system, mannose fructose sorbose family IID component
IOBKPLHJ_01629 2.5e-136 manY G PTS system
IOBKPLHJ_01630 4.2e-189 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IOBKPLHJ_01632 6e-82 S COG NOG38524 non supervised orthologous group
IOBKPLHJ_01633 1.8e-253 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOBKPLHJ_01634 1.4e-101 J Acetyltransferase (GNAT) domain
IOBKPLHJ_01635 2.7e-111 yjbF S SNARE associated Golgi protein
IOBKPLHJ_01636 3.2e-152 I alpha/beta hydrolase fold
IOBKPLHJ_01637 4.5e-160 hipB K Helix-turn-helix
IOBKPLHJ_01638 2.1e-93 F Nucleoside 2-deoxyribosyltransferase
IOBKPLHJ_01639 2.1e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IOBKPLHJ_01640 0.0 fhaB M Rib/alpha-like repeat
IOBKPLHJ_01641 0.0 fhaB M Rib/alpha-like repeat
IOBKPLHJ_01642 2.4e-163
IOBKPLHJ_01643 0.0 ydgH S MMPL family
IOBKPLHJ_01644 2.3e-96 yobS K Bacterial regulatory proteins, tetR family
IOBKPLHJ_01645 1.5e-148 3.5.2.6 V Beta-lactamase enzyme family
IOBKPLHJ_01646 1.5e-153 corA P CorA-like Mg2+ transporter protein
IOBKPLHJ_01647 1.9e-231 G Bacterial extracellular solute-binding protein
IOBKPLHJ_01648 3.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
IOBKPLHJ_01649 9.4e-147 gtsC P Binding-protein-dependent transport system inner membrane component
IOBKPLHJ_01650 2.2e-154 gtsB P ABC-type sugar transport systems, permease components
IOBKPLHJ_01651 7.1e-203 malK P ATPases associated with a variety of cellular activities
IOBKPLHJ_01652 2.8e-284 pipD E Dipeptidase
IOBKPLHJ_01653 1.6e-157 endA F DNA RNA non-specific endonuclease
IOBKPLHJ_01654 1.9e-183 dnaQ 2.7.7.7 L EXOIII
IOBKPLHJ_01655 1.4e-155 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IOBKPLHJ_01656 1.5e-115 yviA S Protein of unknown function (DUF421)
IOBKPLHJ_01657 3.4e-74 S Protein of unknown function (DUF3290)
IOBKPLHJ_01658 0.0 sdrF M domain protein
IOBKPLHJ_01659 4.5e-140 pnuC H nicotinamide mononucleotide transporter
IOBKPLHJ_01660 6.2e-264
IOBKPLHJ_01661 3.5e-48
IOBKPLHJ_01662 1.5e-143 S PAS domain
IOBKPLHJ_01663 1.4e-295 V ABC transporter transmembrane region
IOBKPLHJ_01664 1.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IOBKPLHJ_01665 1.8e-127 T Transcriptional regulatory protein, C terminal
IOBKPLHJ_01666 5.4e-245 T GHKL domain
IOBKPLHJ_01667 2.1e-86 S Peptidase propeptide and YPEB domain
IOBKPLHJ_01668 2.3e-97 S Peptidase propeptide and YPEB domain
IOBKPLHJ_01669 8.2e-76 yybA 2.3.1.57 K Transcriptional regulator
IOBKPLHJ_01670 6.8e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IOBKPLHJ_01671 0.0 E ABC transporter, substratebinding protein
IOBKPLHJ_01672 1.1e-54 ypaA S Protein of unknown function (DUF1304)
IOBKPLHJ_01673 4.6e-100 S Peptidase propeptide and YPEB domain
IOBKPLHJ_01674 9.9e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOBKPLHJ_01675 3.5e-171 coaA 2.7.1.33 F Pantothenic acid kinase
IOBKPLHJ_01676 6.7e-104 E GDSL-like Lipase/Acylhydrolase
IOBKPLHJ_01677 9.9e-82 yjcF S Acetyltransferase (GNAT) domain
IOBKPLHJ_01678 1.9e-62 aatB ET ABC transporter substrate-binding protein
IOBKPLHJ_01680 4.2e-106 3.2.2.20 K acetyltransferase
IOBKPLHJ_01681 3.4e-91
IOBKPLHJ_01682 4.3e-155
IOBKPLHJ_01683 4.1e-269 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
IOBKPLHJ_01684 1.5e-138 glvR K Helix-turn-helix domain, rpiR family
IOBKPLHJ_01685 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
IOBKPLHJ_01686 1.9e-15
IOBKPLHJ_01687 2.1e-48
IOBKPLHJ_01688 2.1e-64 2.7.1.191 G PTS system fructose IIA component
IOBKPLHJ_01689 0.0 3.6.3.8 P P-type ATPase
IOBKPLHJ_01690 1.1e-127
IOBKPLHJ_01691 1.6e-241 S response to antibiotic
IOBKPLHJ_01692 1.7e-134 cysA V ABC transporter, ATP-binding protein
IOBKPLHJ_01693 0.0 V FtsX-like permease family
IOBKPLHJ_01694 8.5e-127 pgm3 5.4.2.11 G Phosphoglycerate mutase family
IOBKPLHJ_01695 9.9e-126 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IOBKPLHJ_01696 0.0 helD 3.6.4.12 L DNA helicase
IOBKPLHJ_01697 3e-108 glnP P ABC transporter permease
IOBKPLHJ_01698 9e-110 glnQ 3.6.3.21 E ABC transporter
IOBKPLHJ_01699 3e-70 aatB ET ABC transporter substrate-binding protein
IOBKPLHJ_01701 4.4e-311 asdA 4.1.1.12 E Aminotransferase
IOBKPLHJ_01702 3.2e-303 aspT P Predicted Permease Membrane Region
IOBKPLHJ_01703 4.2e-189 S Domain of unknown function (DUF4767)
IOBKPLHJ_01704 2.5e-184 S Membrane
IOBKPLHJ_01705 7.1e-149 xth 3.1.11.2 L exodeoxyribonuclease III
IOBKPLHJ_01706 7.9e-188 K helix_turn_helix, arabinose operon control protein
IOBKPLHJ_01707 7.8e-188 K helix_turn_helix, arabinose operon control protein
IOBKPLHJ_01708 4.7e-149 K Helix-turn-helix domain, rpiR family
IOBKPLHJ_01709 7.7e-202 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
IOBKPLHJ_01710 3.7e-157 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOBKPLHJ_01711 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOBKPLHJ_01712 1.6e-298 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOBKPLHJ_01713 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOBKPLHJ_01714 2.5e-158 K CAT RNA binding domain
IOBKPLHJ_01715 0.0 M Leucine-rich repeat (LRR) protein
IOBKPLHJ_01717 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IOBKPLHJ_01718 1.2e-91
IOBKPLHJ_01719 1.6e-182
IOBKPLHJ_01720 9.7e-271 S Uncharacterised protein conserved in bacteria (DUF2326)
IOBKPLHJ_01721 7.6e-10
IOBKPLHJ_01727 2.2e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOBKPLHJ_01728 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOBKPLHJ_01729 2.3e-63 L PFAM Integrase catalytic region
IOBKPLHJ_01730 1e-136 L transposase activity
IOBKPLHJ_01731 5.2e-234 L COG3547 Transposase and inactivated derivatives
IOBKPLHJ_01732 4.6e-266 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
IOBKPLHJ_01733 1.2e-200 glf 5.4.99.9 M UDP-galactopyranose mutase
IOBKPLHJ_01734 4.2e-218 S Psort location CytoplasmicMembrane, score 9.99
IOBKPLHJ_01735 1.2e-188 M Glycosyltransferase like family 2
IOBKPLHJ_01736 2.8e-117 M transferase activity, transferring glycosyl groups
IOBKPLHJ_01737 2.5e-166 glfT1 1.1.1.133 S Glycosyltransferase like family 2
IOBKPLHJ_01738 1.6e-148 cps1D M Domain of unknown function (DUF4422)
IOBKPLHJ_01739 1.1e-123 rfbP M Bacterial sugar transferase
IOBKPLHJ_01740 3.6e-148 ywqE 3.1.3.48 GM PHP domain protein
IOBKPLHJ_01741 1.2e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IOBKPLHJ_01742 1.6e-141 epsB M biosynthesis protein
IOBKPLHJ_01743 4e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOBKPLHJ_01744 2.6e-190 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOBKPLHJ_01745 3.2e-189 S Cysteine-rich secretory protein family
IOBKPLHJ_01746 0.0 2.7.13.3 M Mycoplasma protein of unknown function, DUF285
IOBKPLHJ_01747 3.7e-128 M NlpC/P60 family
IOBKPLHJ_01748 2.3e-126 M NlpC P60 family protein
IOBKPLHJ_01749 7.6e-84 M NlpC/P60 family
IOBKPLHJ_01750 1.8e-85 gmk2 2.7.4.8 F Guanylate kinase homologues.
IOBKPLHJ_01751 5.6e-33
IOBKPLHJ_01752 1e-279 S O-antigen ligase like membrane protein
IOBKPLHJ_01753 3.1e-110
IOBKPLHJ_01754 3.8e-78 nrdI F NrdI Flavodoxin like
IOBKPLHJ_01755 1.7e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOBKPLHJ_01756 7.8e-78
IOBKPLHJ_01757 7.7e-137 yvpB S Peptidase_C39 like family
IOBKPLHJ_01758 5.2e-53 yitW S Iron-sulfur cluster assembly protein
IOBKPLHJ_01759 8.8e-47 sufB O assembly protein SufB
IOBKPLHJ_01760 3e-34 sufC O FeS assembly ATPase SufC
IOBKPLHJ_01761 7.8e-85 S Threonine/Serine exporter, ThrE
IOBKPLHJ_01762 3.7e-137 thrE S Putative threonine/serine exporter
IOBKPLHJ_01763 2.1e-293 S ABC transporter
IOBKPLHJ_01764 3.6e-61
IOBKPLHJ_01765 1.3e-45 rimL J Acetyltransferase (GNAT) domain
IOBKPLHJ_01766 1.5e-223 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOBKPLHJ_01767 0.0 pepF E oligoendopeptidase F
IOBKPLHJ_01768 6.7e-44 P transmembrane transport
IOBKPLHJ_01769 7e-265 lctP C L-lactate permease
IOBKPLHJ_01770 1.4e-62 pdxH S Pyridoxamine 5'-phosphate oxidase
IOBKPLHJ_01771 7.9e-135 znuB U ABC 3 transport family
IOBKPLHJ_01772 1e-116 fhuC P ABC transporter
IOBKPLHJ_01773 2.4e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
IOBKPLHJ_01774 2.5e-43 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOBKPLHJ_01775 5.1e-75 K LytTr DNA-binding domain
IOBKPLHJ_01776 5.5e-47 S Protein of unknown function (DUF3021)
IOBKPLHJ_01777 7.5e-132 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
IOBKPLHJ_01778 2.4e-204 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
IOBKPLHJ_01779 3.3e-169 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOBKPLHJ_01780 6.8e-136 fruR K DeoR C terminal sensor domain
IOBKPLHJ_01781 1.1e-195 fic S Fic/DOC family
IOBKPLHJ_01782 3.9e-218 natB CP ABC-2 family transporter protein
IOBKPLHJ_01783 2.6e-166 natA S ABC transporter, ATP-binding protein
IOBKPLHJ_01784 6.2e-08
IOBKPLHJ_01785 4e-69
IOBKPLHJ_01786 2.1e-25
IOBKPLHJ_01787 8.2e-31 yozG K Transcriptional regulator
IOBKPLHJ_01788 1.5e-89
IOBKPLHJ_01789 8.8e-21
IOBKPLHJ_01794 8.1e-209 blpT
IOBKPLHJ_01795 3.4e-106 M Transport protein ComB
IOBKPLHJ_01796 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOBKPLHJ_01797 4.2e-07
IOBKPLHJ_01799 1.2e-146 K LytTr DNA-binding domain
IOBKPLHJ_01800 2.8e-233 2.7.13.3 T GHKL domain
IOBKPLHJ_01804 7e-110
IOBKPLHJ_01806 5.1e-109 S CAAX protease self-immunity
IOBKPLHJ_01807 1.2e-216 S CAAX protease self-immunity
IOBKPLHJ_01808 1.4e-37 S Enterocin A Immunity
IOBKPLHJ_01809 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IOBKPLHJ_01810 1.1e-26
IOBKPLHJ_01811 1.5e-33
IOBKPLHJ_01812 4e-53 S Enterocin A Immunity
IOBKPLHJ_01813 9.4e-49 S Enterocin A Immunity
IOBKPLHJ_01814 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IOBKPLHJ_01815 2.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOBKPLHJ_01816 5.8e-195 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
IOBKPLHJ_01817 2.5e-121 K response regulator
IOBKPLHJ_01818 0.0 V ABC transporter
IOBKPLHJ_01819 1.3e-304 V ABC transporter, ATP-binding protein
IOBKPLHJ_01820 2e-138 XK27_01040 S Protein of unknown function (DUF1129)
IOBKPLHJ_01821 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOBKPLHJ_01822 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
IOBKPLHJ_01823 3.4e-155 spo0J K Belongs to the ParB family
IOBKPLHJ_01824 1.3e-137 soj D Sporulation initiation inhibitor
IOBKPLHJ_01825 7.2e-147 noc K Belongs to the ParB family
IOBKPLHJ_01826 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IOBKPLHJ_01827 7.9e-54 cvpA S Colicin V production protein
IOBKPLHJ_01828 3.5e-182 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOBKPLHJ_01829 8.1e-148 3.1.3.48 T Tyrosine phosphatase family
IOBKPLHJ_01830 2.7e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
IOBKPLHJ_01831 7.6e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
IOBKPLHJ_01832 1.3e-111 K WHG domain
IOBKPLHJ_01833 1.5e-36
IOBKPLHJ_01834 1.1e-277 pipD E Dipeptidase
IOBKPLHJ_01835 9.8e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IOBKPLHJ_01836 1.3e-180 hrtB V ABC transporter permease
IOBKPLHJ_01837 4.8e-96 ygfC K Bacterial regulatory proteins, tetR family
IOBKPLHJ_01838 7.1e-112 3.1.3.73 G phosphoglycerate mutase
IOBKPLHJ_01839 1.3e-139 aroD S Alpha/beta hydrolase family
IOBKPLHJ_01840 2e-143 S Belongs to the UPF0246 family
IOBKPLHJ_01841 3.8e-119
IOBKPLHJ_01842 4.6e-159 2.7.7.12 C Domain of unknown function (DUF4931)
IOBKPLHJ_01843 9.3e-220 S Putative peptidoglycan binding domain
IOBKPLHJ_01844 2.6e-26
IOBKPLHJ_01845 1.3e-252 dtpT U amino acid peptide transporter
IOBKPLHJ_01846 0.0 pepN 3.4.11.2 E aminopeptidase
IOBKPLHJ_01847 4.5e-61 lysM M LysM domain
IOBKPLHJ_01848 4.7e-177
IOBKPLHJ_01849 2.8e-102 mdtG EGP Major Facilitator Superfamily
IOBKPLHJ_01850 2.9e-114 mdtG EGP Major facilitator Superfamily
IOBKPLHJ_01852 6e-213 I transferase activity, transferring acyl groups other than amino-acyl groups
IOBKPLHJ_01853 5.9e-91 ymdB S Macro domain protein
IOBKPLHJ_01854 0.0 nisT V ABC transporter
IOBKPLHJ_01855 3.7e-07
IOBKPLHJ_01857 1.6e-146 K Helix-turn-helix XRE-family like proteins
IOBKPLHJ_01859 6.7e-84
IOBKPLHJ_01860 1.4e-148 malG P ABC transporter permease
IOBKPLHJ_01861 7.9e-252 malF P Binding-protein-dependent transport system inner membrane component
IOBKPLHJ_01862 5.9e-214 malE G Bacterial extracellular solute-binding protein
IOBKPLHJ_01863 1.6e-210 msmX P Belongs to the ABC transporter superfamily
IOBKPLHJ_01864 7e-264 L COG2963 Transposase and inactivated derivatives
IOBKPLHJ_01865 9.6e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IOBKPLHJ_01866 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IOBKPLHJ_01867 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IOBKPLHJ_01868 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IOBKPLHJ_01869 9.4e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOBKPLHJ_01870 4.8e-179 yvdE K helix_turn _helix lactose operon repressor
IOBKPLHJ_01871 6.7e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
IOBKPLHJ_01872 6.8e-295 V ABC transporter transmembrane region
IOBKPLHJ_01873 5e-75
IOBKPLHJ_01874 3.4e-16
IOBKPLHJ_01875 1.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOBKPLHJ_01876 2.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOBKPLHJ_01877 3.3e-57 S Protein conserved in bacteria
IOBKPLHJ_01878 2.2e-170 L transposase, IS605 OrfB family
IOBKPLHJ_01879 7.6e-134 cobQ S glutamine amidotransferase
IOBKPLHJ_01880 9.5e-83 M NlpC/P60 family
IOBKPLHJ_01881 1.6e-166 EG EamA-like transporter family
IOBKPLHJ_01882 3.2e-167 EG EamA-like transporter family
IOBKPLHJ_01883 1.6e-163 yicL EG EamA-like transporter family
IOBKPLHJ_01884 3.1e-105
IOBKPLHJ_01885 1.5e-56
IOBKPLHJ_01886 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOBKPLHJ_01887 3.2e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOBKPLHJ_01888 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOBKPLHJ_01891 1.5e-202 4.2.1.126 S Bacterial protein of unknown function (DUF871)
IOBKPLHJ_01892 3e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
IOBKPLHJ_01893 0.0 L Transposase
IOBKPLHJ_01894 1.1e-118 frnE Q DSBA-like thioredoxin domain
IOBKPLHJ_01895 1.1e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOBKPLHJ_01896 3.6e-117 M1-798 K Rhodanese Homology Domain
IOBKPLHJ_01898 1.1e-52 yusE CO Thioredoxin
IOBKPLHJ_01899 1.4e-240 steT_1 E amino acid
IOBKPLHJ_01900 8e-142 puuD S peptidase C26
IOBKPLHJ_01901 2.4e-219 yifK E Amino acid permease
IOBKPLHJ_01902 3.2e-205 cycA E Amino acid permease
IOBKPLHJ_01903 7.1e-122
IOBKPLHJ_01904 0.0 L Transposase
IOBKPLHJ_01905 6.6e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOBKPLHJ_01906 0.0 clpE O AAA domain (Cdc48 subfamily)
IOBKPLHJ_01907 5.1e-170 S Alpha/beta hydrolase of unknown function (DUF915)
IOBKPLHJ_01908 1.4e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOBKPLHJ_01909 5e-125 XK27_06785 V ABC transporter, ATP-binding protein
IOBKPLHJ_01910 4.4e-211 XK27_06780 V ABC transporter permease
IOBKPLHJ_01911 5.1e-229 XK27_06780 V ABC transporter permease
IOBKPLHJ_01912 9.6e-36
IOBKPLHJ_01913 7.4e-289 ytgP S Polysaccharide biosynthesis protein
IOBKPLHJ_01914 4.3e-167 lysA2 M Glycosyl hydrolases family 25
IOBKPLHJ_01915 4.4e-126 S Protein of unknown function (DUF975)
IOBKPLHJ_01916 2.7e-61
IOBKPLHJ_01917 2e-177 pbpX2 V Beta-lactamase
IOBKPLHJ_01918 3.9e-248 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOBKPLHJ_01919 7.4e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOBKPLHJ_01920 2.6e-241 dltB M MBOAT, membrane-bound O-acyltransferase family
IOBKPLHJ_01921 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOBKPLHJ_01922 7.6e-18 S D-Ala-teichoic acid biosynthesis protein
IOBKPLHJ_01923 3.6e-40
IOBKPLHJ_01924 9.1e-217 ywhK S Membrane
IOBKPLHJ_01925 2.1e-82 ykuL S (CBS) domain
IOBKPLHJ_01926 0.0 cadA P P-type ATPase
IOBKPLHJ_01927 5e-194 napA P Sodium/hydrogen exchanger family
IOBKPLHJ_01928 3.5e-72 S Putative adhesin
IOBKPLHJ_01929 4.3e-286 V ABC transporter transmembrane region
IOBKPLHJ_01930 2.8e-154 mutR K Helix-turn-helix XRE-family like proteins
IOBKPLHJ_01931 3.2e-97 M CHAP domain
IOBKPLHJ_01932 1.5e-68 K Helix-turn-helix XRE-family like proteins
IOBKPLHJ_01933 2.7e-120 S CAAX protease self-immunity
IOBKPLHJ_01934 1.6e-194 S DUF218 domain
IOBKPLHJ_01935 0.0 macB_3 V ABC transporter, ATP-binding protein
IOBKPLHJ_01936 1.6e-103 S ECF transporter, substrate-specific component
IOBKPLHJ_01937 5.6e-186 tcsA S ABC transporter substrate-binding protein PnrA-like
IOBKPLHJ_01938 5.6e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
IOBKPLHJ_01939 1.7e-287 xylG 3.6.3.17 S ABC transporter
IOBKPLHJ_01940 5.1e-207 yufP S Belongs to the binding-protein-dependent transport system permease family
IOBKPLHJ_01941 5.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
IOBKPLHJ_01942 1.7e-159 yeaE S Aldo/keto reductase family
IOBKPLHJ_01943 2.5e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOBKPLHJ_01944 4.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IOBKPLHJ_01945 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IOBKPLHJ_01946 8.5e-145 cof S haloacid dehalogenase-like hydrolase
IOBKPLHJ_01947 1.1e-231 pbuG S permease
IOBKPLHJ_01948 4.6e-263 L COG2963 Transposase and inactivated derivatives
IOBKPLHJ_01949 5.1e-128 K helix_turn_helix, mercury resistance
IOBKPLHJ_01950 5e-227 pbuG S permease
IOBKPLHJ_01951 5.6e-177 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
IOBKPLHJ_01952 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
IOBKPLHJ_01953 3.4e-223 pbuG S permease
IOBKPLHJ_01954 1.2e-23
IOBKPLHJ_01955 3.8e-309 E ABC transporter, substratebinding protein
IOBKPLHJ_01956 3.9e-75 atkY K Penicillinase repressor
IOBKPLHJ_01957 1.8e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOBKPLHJ_01958 3.7e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOBKPLHJ_01959 0.0 copA 3.6.3.54 P P-type ATPase
IOBKPLHJ_01960 2.7e-175 XK27_05540 S DUF218 domain
IOBKPLHJ_01961 2.4e-130 WQ51_05710 S Mitochondrial biogenesis AIM24
IOBKPLHJ_01962 5.5e-118 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IOBKPLHJ_01963 1.5e-18
IOBKPLHJ_01964 1.2e-213
IOBKPLHJ_01965 1.1e-281 clcA P chloride
IOBKPLHJ_01966 5.8e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOBKPLHJ_01967 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOBKPLHJ_01968 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOBKPLHJ_01969 3.9e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOBKPLHJ_01970 5.1e-151 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOBKPLHJ_01971 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOBKPLHJ_01972 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)