ORF_ID e_value Gene_name EC_number CAZy COGs Description
MIDIMPMF_00001 2.2e-38 azlD E Branched-chain amino acid transport protein (AzlD)
MIDIMPMF_00002 4.8e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
MIDIMPMF_00003 2.1e-96 ptpA 3.1.3.48 T low molecular weight
MIDIMPMF_00004 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
MIDIMPMF_00005 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIDIMPMF_00006 3.8e-72 attW O OsmC-like protein
MIDIMPMF_00007 1.6e-191 T Universal stress protein family
MIDIMPMF_00008 2.4e-107 M NlpC/P60 family
MIDIMPMF_00009 3.1e-176 usp 3.5.1.28 CBM50 S CHAP domain
MIDIMPMF_00010 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIDIMPMF_00011 2.6e-39
MIDIMPMF_00012 2.3e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIDIMPMF_00013 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
MIDIMPMF_00014 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MIDIMPMF_00015 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MIDIMPMF_00016 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MIDIMPMF_00018 4.3e-217 araJ EGP Major facilitator Superfamily
MIDIMPMF_00019 0.0 S Domain of unknown function (DUF4037)
MIDIMPMF_00020 1.5e-112 S Protein of unknown function (DUF4125)
MIDIMPMF_00021 7.3e-135
MIDIMPMF_00022 3.6e-289 pspC KT PspC domain
MIDIMPMF_00023 2.7e-266 tcsS3 KT PspC domain
MIDIMPMF_00024 9.2e-126 degU K helix_turn_helix, Lux Regulon
MIDIMPMF_00025 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIDIMPMF_00027 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MIDIMPMF_00028 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
MIDIMPMF_00029 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIDIMPMF_00030 1.2e-94
MIDIMPMF_00032 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
MIDIMPMF_00034 3.3e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIDIMPMF_00035 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
MIDIMPMF_00036 5.1e-212 I Diacylglycerol kinase catalytic domain
MIDIMPMF_00037 1.7e-151 arbG K CAT RNA binding domain
MIDIMPMF_00038 0.0 crr G pts system, glucose-specific IIABC component
MIDIMPMF_00040 1.2e-13 M Spy0128-like isopeptide containing domain
MIDIMPMF_00041 1.2e-18 M Spy0128-like isopeptide containing domain
MIDIMPMF_00042 6.1e-43 M Spy0128-like isopeptide containing domain
MIDIMPMF_00043 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MIDIMPMF_00044 4.4e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIDIMPMF_00045 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MIDIMPMF_00046 1.4e-203 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIDIMPMF_00047 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIDIMPMF_00049 1.2e-106
MIDIMPMF_00050 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIDIMPMF_00051 2.2e-232 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
MIDIMPMF_00052 3.2e-234 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIDIMPMF_00053 2e-82 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIDIMPMF_00054 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MIDIMPMF_00055 2.8e-188 nusA K Participates in both transcription termination and antitermination
MIDIMPMF_00056 2.3e-146
MIDIMPMF_00057 2.5e-88 L Transposase and inactivated derivatives
MIDIMPMF_00059 1.3e-153 E Transglutaminase/protease-like homologues
MIDIMPMF_00060 0.0 gcs2 S A circularly permuted ATPgrasp
MIDIMPMF_00061 5.4e-172 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MIDIMPMF_00062 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
MIDIMPMF_00063 2.8e-64 rplQ J Ribosomal protein L17
MIDIMPMF_00064 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIDIMPMF_00065 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIDIMPMF_00066 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIDIMPMF_00067 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MIDIMPMF_00068 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIDIMPMF_00069 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MIDIMPMF_00070 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MIDIMPMF_00071 6.1e-63 rplO J binds to the 23S rRNA
MIDIMPMF_00072 1e-24 rpmD J Ribosomal protein L30p/L7e
MIDIMPMF_00073 6.5e-99 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIDIMPMF_00074 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIDIMPMF_00075 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MIDIMPMF_00076 9.3e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIDIMPMF_00077 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIDIMPMF_00078 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIDIMPMF_00079 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIDIMPMF_00080 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIDIMPMF_00081 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIDIMPMF_00082 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
MIDIMPMF_00083 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIDIMPMF_00084 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIDIMPMF_00085 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIDIMPMF_00086 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIDIMPMF_00087 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIDIMPMF_00088 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MIDIMPMF_00089 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
MIDIMPMF_00090 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIDIMPMF_00091 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
MIDIMPMF_00092 8.6e-160 ywiC S YwiC-like protein
MIDIMPMF_00093 1.5e-166 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MIDIMPMF_00094 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MIDIMPMF_00095 4.8e-232 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MIDIMPMF_00096 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MIDIMPMF_00097 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
MIDIMPMF_00098 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIDIMPMF_00099 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MIDIMPMF_00100 8.9e-112
MIDIMPMF_00101 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
MIDIMPMF_00102 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
MIDIMPMF_00104 1.1e-239 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIDIMPMF_00105 8.5e-226 dapC E Aminotransferase class I and II
MIDIMPMF_00106 9e-61 fdxA C 4Fe-4S binding domain
MIDIMPMF_00107 7.7e-214 murB 1.3.1.98 M Cell wall formation
MIDIMPMF_00108 1.9e-25 rpmG J Ribosomal protein L33
MIDIMPMF_00112 6e-51 moxR S ATPase family associated with various cellular activities (AAA)
MIDIMPMF_00113 3e-131 bla1 3.5.2.6 V Beta-lactamase enzyme family
MIDIMPMF_00114 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIDIMPMF_00115 6.3e-148
MIDIMPMF_00116 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
MIDIMPMF_00117 1.8e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
MIDIMPMF_00118 3.2e-38 fmdB S Putative regulatory protein
MIDIMPMF_00119 1.3e-109 flgA NO SAF
MIDIMPMF_00120 2.8e-41
MIDIMPMF_00121 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MIDIMPMF_00122 3.2e-239 T Forkhead associated domain
MIDIMPMF_00124 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MIDIMPMF_00125 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIDIMPMF_00126 4.5e-183 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
MIDIMPMF_00127 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
MIDIMPMF_00128 1.1e-221 pbuO S Permease family
MIDIMPMF_00129 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MIDIMPMF_00130 5.2e-173 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MIDIMPMF_00131 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIDIMPMF_00132 6.2e-180 pstA P Phosphate transport system permease
MIDIMPMF_00133 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
MIDIMPMF_00134 2.3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
MIDIMPMF_00135 3.7e-128 KT Transcriptional regulatory protein, C terminal
MIDIMPMF_00136 7.9e-244 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MIDIMPMF_00137 8.7e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIDIMPMF_00138 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIDIMPMF_00139 1.8e-107 K helix_turn_helix, Arsenical Resistance Operon Repressor
MIDIMPMF_00140 2.5e-245 EGP Major facilitator Superfamily
MIDIMPMF_00141 1.5e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIDIMPMF_00142 1e-166 L Excalibur calcium-binding domain
MIDIMPMF_00143 1.3e-267 pepC 3.4.22.40 E Peptidase C1-like family
MIDIMPMF_00144 3.7e-53 D nuclear chromosome segregation
MIDIMPMF_00145 3e-127 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIDIMPMF_00146 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIDIMPMF_00147 1.8e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
MIDIMPMF_00148 0.0 yegQ O Peptidase family U32 C-terminal domain
MIDIMPMF_00149 8.7e-94 L Transposase and inactivated derivatives IS30 family
MIDIMPMF_00150 3.8e-96 L Transposase and inactivated derivatives IS30 family
MIDIMPMF_00151 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
MIDIMPMF_00152 2.2e-41 nrdH O Glutaredoxin
MIDIMPMF_00153 7.3e-98 nrdI F Probably involved in ribonucleotide reductase function
MIDIMPMF_00154 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIDIMPMF_00155 1.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIDIMPMF_00156 2.3e-73 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MIDIMPMF_00157 0.0 S Predicted membrane protein (DUF2207)
MIDIMPMF_00158 3.7e-94 lemA S LemA family
MIDIMPMF_00159 2.8e-115 xylR K purine nucleotide biosynthetic process
MIDIMPMF_00160 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MIDIMPMF_00161 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIDIMPMF_00162 1.2e-118
MIDIMPMF_00163 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MIDIMPMF_00165 1.9e-161 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MIDIMPMF_00166 3.8e-99 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MIDIMPMF_00167 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
MIDIMPMF_00168 3.6e-307 pccB I Carboxyl transferase domain
MIDIMPMF_00169 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MIDIMPMF_00170 2.1e-92 bioY S BioY family
MIDIMPMF_00171 4.4e-152 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MIDIMPMF_00172 0.0
MIDIMPMF_00173 5.9e-146 QT PucR C-terminal helix-turn-helix domain
MIDIMPMF_00174 1e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MIDIMPMF_00175 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MIDIMPMF_00176 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MIDIMPMF_00177 6e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIDIMPMF_00178 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIDIMPMF_00179 2.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIDIMPMF_00180 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIDIMPMF_00181 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIDIMPMF_00182 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
MIDIMPMF_00183 9.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIDIMPMF_00185 9.2e-36
MIDIMPMF_00186 0.0 K RNA polymerase II activating transcription factor binding
MIDIMPMF_00187 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MIDIMPMF_00188 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIDIMPMF_00190 2.2e-102 mntP P Probably functions as a manganese efflux pump
MIDIMPMF_00191 1.4e-125
MIDIMPMF_00192 1.5e-132 KT Transcriptional regulatory protein, C terminal
MIDIMPMF_00193 1.1e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIDIMPMF_00194 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
MIDIMPMF_00195 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MIDIMPMF_00196 0.0 S domain protein
MIDIMPMF_00197 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
MIDIMPMF_00198 2.4e-90 lrp_3 K helix_turn_helix ASNC type
MIDIMPMF_00199 5.7e-233 E Aminotransferase class I and II
MIDIMPMF_00200 5.1e-306 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIDIMPMF_00201 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
MIDIMPMF_00203 3.3e-52 S Protein of unknown function (DUF2469)
MIDIMPMF_00204 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
MIDIMPMF_00205 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIDIMPMF_00206 1.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MIDIMPMF_00207 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIDIMPMF_00208 6.2e-61 V ABC transporter
MIDIMPMF_00209 3.3e-59 V ABC transporter
MIDIMPMF_00210 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
MIDIMPMF_00211 1.3e-128 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIDIMPMF_00212 1.3e-214 rmuC S RmuC family
MIDIMPMF_00213 9.6e-43 csoR S Metal-sensitive transcriptional repressor
MIDIMPMF_00214 0.0 pacS 3.6.3.54 P E1-E2 ATPase
MIDIMPMF_00215 0.0 ubiB S ABC1 family
MIDIMPMF_00216 3.5e-19 S granule-associated protein
MIDIMPMF_00217 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MIDIMPMF_00218 9.5e-281 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
MIDIMPMF_00219 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MIDIMPMF_00220 1.9e-248 dinF V MatE
MIDIMPMF_00221 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MIDIMPMF_00222 1e-54 glnB K Nitrogen regulatory protein P-II
MIDIMPMF_00223 7.7e-220 amt U Ammonium Transporter Family
MIDIMPMF_00224 6.2e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MIDIMPMF_00226 2.7e-116 icaR K Bacterial regulatory proteins, tetR family
MIDIMPMF_00227 1.9e-197 XK27_01805 M Glycosyltransferase like family 2
MIDIMPMF_00228 0.0 S Glycosyl hydrolases related to GH101 family, GH129
MIDIMPMF_00229 1.7e-303 pepD E Peptidase family C69
MIDIMPMF_00231 2.9e-19 XK26_04485 P Cobalt transport protein
MIDIMPMF_00232 1.1e-68 XK26_04485 P Cobalt transport protein
MIDIMPMF_00233 7.5e-82
MIDIMPMF_00234 0.0 V ABC transporter transmembrane region
MIDIMPMF_00235 1.8e-301 V ABC transporter, ATP-binding protein
MIDIMPMF_00236 1e-81 K Winged helix DNA-binding domain
MIDIMPMF_00237 1.3e-14
MIDIMPMF_00238 1.1e-298 M LPXTG cell wall anchor motif
MIDIMPMF_00239 4.8e-194 M chlorophyll binding
MIDIMPMF_00240 1.4e-212 M chlorophyll binding
MIDIMPMF_00241 3.9e-176 3.4.22.70 M Sortase family
MIDIMPMF_00243 6.8e-161 S Sucrose-6F-phosphate phosphohydrolase
MIDIMPMF_00244 3.5e-241 S Putative ABC-transporter type IV
MIDIMPMF_00245 7e-81
MIDIMPMF_00246 1.5e-26 Q phosphatase activity
MIDIMPMF_00247 1.4e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
MIDIMPMF_00248 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MIDIMPMF_00249 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MIDIMPMF_00250 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIDIMPMF_00251 4.6e-67 S haloacid dehalogenase-like hydrolase
MIDIMPMF_00252 3.6e-131 yydK K UTRA
MIDIMPMF_00253 1.3e-70 S FMN_bind
MIDIMPMF_00254 1.8e-147 macB V ABC transporter, ATP-binding protein
MIDIMPMF_00255 2.4e-205 Z012_06715 V FtsX-like permease family
MIDIMPMF_00256 9.7e-223 macB_2 V ABC transporter permease
MIDIMPMF_00257 3.2e-234 S Predicted membrane protein (DUF2318)
MIDIMPMF_00258 6.4e-109 tpd P Fe2+ transport protein
MIDIMPMF_00259 4.6e-308 efeU_1 P Iron permease FTR1 family
MIDIMPMF_00260 5.9e-22 G MFS/sugar transport protein
MIDIMPMF_00261 7.6e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MIDIMPMF_00262 1.4e-88 S Fic/DOC family
MIDIMPMF_00263 1.2e-32 S Fic/DOC family
MIDIMPMF_00264 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIDIMPMF_00265 5e-38 ptsH G PTS HPr component phosphorylation site
MIDIMPMF_00266 4.4e-200 K helix_turn _helix lactose operon repressor
MIDIMPMF_00267 6.3e-213 holB 2.7.7.7 L DNA polymerase III
MIDIMPMF_00268 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIDIMPMF_00269 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIDIMPMF_00270 1.4e-188 3.6.1.27 I PAP2 superfamily
MIDIMPMF_00271 0.0 vpr M PA domain
MIDIMPMF_00272 1.6e-123 yplQ S Haemolysin-III related
MIDIMPMF_00273 5.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
MIDIMPMF_00274 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MIDIMPMF_00275 2.7e-65 L Helix-turn-helix domain
MIDIMPMF_00276 2e-115 insK L Integrase core domain
MIDIMPMF_00277 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIDIMPMF_00278 3.9e-278 S Calcineurin-like phosphoesterase
MIDIMPMF_00279 4.3e-14 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MIDIMPMF_00280 2.7e-285 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MIDIMPMF_00281 1.7e-116
MIDIMPMF_00282 2.6e-213 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIDIMPMF_00283 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
MIDIMPMF_00284 5.3e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MIDIMPMF_00285 1.9e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIDIMPMF_00286 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
MIDIMPMF_00287 3.7e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
MIDIMPMF_00288 6.9e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
MIDIMPMF_00289 1.1e-54 U TadE-like protein
MIDIMPMF_00290 1.9e-41 S Protein of unknown function (DUF4244)
MIDIMPMF_00291 4.3e-63 gspF NU Type II secretion system (T2SS), protein F
MIDIMPMF_00293 5.1e-122 U Type ii secretion system
MIDIMPMF_00294 9.8e-191 cpaF U Type II IV secretion system protein
MIDIMPMF_00295 3.4e-152 cpaE D bacterial-type flagellum organization
MIDIMPMF_00297 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MIDIMPMF_00298 1.8e-200 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
MIDIMPMF_00299 8.6e-91
MIDIMPMF_00301 2e-58 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MIDIMPMF_00302 4e-209 S Glycosyltransferase, group 2 family protein
MIDIMPMF_00303 9.8e-261
MIDIMPMF_00305 3.3e-26 thiS 2.8.1.10 H ThiS family
MIDIMPMF_00306 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MIDIMPMF_00307 0.0 S Psort location Cytoplasmic, score 8.87
MIDIMPMF_00308 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
MIDIMPMF_00309 1.4e-246 V ABC transporter permease
MIDIMPMF_00310 6.5e-174 V ABC transporter
MIDIMPMF_00311 3e-136 T HD domain
MIDIMPMF_00312 3e-164 S Glutamine amidotransferase domain
MIDIMPMF_00313 0.0 kup P Transport of potassium into the cell
MIDIMPMF_00314 5.9e-185 tatD L TatD related DNase
MIDIMPMF_00315 5.2e-258 xylR 5.3.1.12 G MFS/sugar transport protein
MIDIMPMF_00316 5.9e-16 G Bacterial extracellular solute-binding protein
MIDIMPMF_00317 2.9e-79 K Transcriptional regulator
MIDIMPMF_00318 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIDIMPMF_00319 1.6e-130
MIDIMPMF_00320 8.6e-59
MIDIMPMF_00321 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIDIMPMF_00322 5.9e-126 dedA S SNARE associated Golgi protein
MIDIMPMF_00324 3.5e-134 S HAD hydrolase, family IA, variant 3
MIDIMPMF_00325 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
MIDIMPMF_00326 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
MIDIMPMF_00327 1.3e-85 hspR K transcriptional regulator, MerR family
MIDIMPMF_00328 2.3e-171 dnaJ1 O DnaJ molecular chaperone homology domain
MIDIMPMF_00329 1.4e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIDIMPMF_00330 0.0 dnaK O Heat shock 70 kDa protein
MIDIMPMF_00331 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
MIDIMPMF_00332 2.9e-190 K Psort location Cytoplasmic, score
MIDIMPMF_00334 1.2e-131 G Phosphoglycerate mutase family
MIDIMPMF_00335 5.6e-69 S Protein of unknown function (DUF4235)
MIDIMPMF_00336 1.5e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
MIDIMPMF_00337 1.1e-45
MIDIMPMF_00339 5.4e-160 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
MIDIMPMF_00341 3e-144 cobB2 K Sir2 family
MIDIMPMF_00342 2.2e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MIDIMPMF_00343 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MIDIMPMF_00344 1e-144 ypfH S Phospholipase/Carboxylesterase
MIDIMPMF_00345 0.0 yjcE P Sodium/hydrogen exchanger family
MIDIMPMF_00346 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
MIDIMPMF_00347 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
MIDIMPMF_00348 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
MIDIMPMF_00350 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIDIMPMF_00351 1.1e-269 KLT Domain of unknown function (DUF4032)
MIDIMPMF_00352 2.7e-152
MIDIMPMF_00353 4.2e-178 3.4.22.70 M Sortase family
MIDIMPMF_00354 1.4e-250 M LPXTG-motif cell wall anchor domain protein
MIDIMPMF_00355 0.0 S LPXTG-motif cell wall anchor domain protein
MIDIMPMF_00356 2.3e-101 L Helix-turn-helix domain
MIDIMPMF_00357 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
MIDIMPMF_00358 0.0 KLT Protein tyrosine kinase
MIDIMPMF_00359 1.1e-150 O Thioredoxin
MIDIMPMF_00361 1.4e-212 S G5
MIDIMPMF_00362 2.1e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MIDIMPMF_00363 2.3e-166 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIDIMPMF_00364 6.7e-113 S LytR cell envelope-related transcriptional attenuator
MIDIMPMF_00365 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
MIDIMPMF_00366 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
MIDIMPMF_00367 0.0 M Conserved repeat domain
MIDIMPMF_00368 0.0 murJ KLT MviN-like protein
MIDIMPMF_00369 7.6e-203 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MIDIMPMF_00370 1e-243 parB K Belongs to the ParB family
MIDIMPMF_00371 1.9e-178 parA D CobQ CobB MinD ParA nucleotide binding domain protein
MIDIMPMF_00372 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MIDIMPMF_00373 1.5e-92 jag S Putative single-stranded nucleic acids-binding domain
MIDIMPMF_00374 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
MIDIMPMF_00375 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MIDIMPMF_00376 1.6e-291 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIDIMPMF_00377 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MIDIMPMF_00378 2.1e-241 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIDIMPMF_00379 3.2e-93 S Protein of unknown function (DUF721)
MIDIMPMF_00380 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIDIMPMF_00381 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIDIMPMF_00382 1.2e-73 S Transmembrane domain of unknown function (DUF3566)
MIDIMPMF_00383 2.5e-13 abfA1 3.2.1.55 GH51 G arabinose metabolic process
MIDIMPMF_00384 1.2e-06 S Parallel beta-helix repeats
MIDIMPMF_00385 3.5e-187 G Glycosyl hydrolases family 43
MIDIMPMF_00386 1.6e-187 K Periplasmic binding protein domain
MIDIMPMF_00387 1.2e-227 I Serine aminopeptidase, S33
MIDIMPMF_00388 8.3e-09 K helix_turn _helix lactose operon repressor
MIDIMPMF_00389 9.6e-42 S Protein of unknown function (DUF2442)
MIDIMPMF_00390 4.4e-118 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MIDIMPMF_00391 5.3e-267 hsdBM 2.1.1.72 L Eco57I restriction-modification methylase
MIDIMPMF_00392 2.6e-185 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
MIDIMPMF_00393 2.7e-227
MIDIMPMF_00395 6.4e-184 L Phage integrase family
MIDIMPMF_00398 1.5e-258 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIDIMPMF_00399 5.2e-122 gntR K FCD
MIDIMPMF_00400 2.4e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MIDIMPMF_00401 0.0 3.2.1.55 GH51 G arabinose metabolic process
MIDIMPMF_00404 0.0 G Glycosyl hydrolase family 20, domain 2
MIDIMPMF_00405 3.7e-188 K helix_turn _helix lactose operon repressor
MIDIMPMF_00406 4.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MIDIMPMF_00407 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MIDIMPMF_00408 5.2e-252 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MIDIMPMF_00409 3.3e-135 S Protein of unknown function DUF45
MIDIMPMF_00410 1.9e-83 dps P Belongs to the Dps family
MIDIMPMF_00411 1.3e-188 yddG EG EamA-like transporter family
MIDIMPMF_00412 1e-240 ytfL P Transporter associated domain
MIDIMPMF_00413 7.5e-93 K helix_turn _helix lactose operon repressor
MIDIMPMF_00414 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MIDIMPMF_00415 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MIDIMPMF_00416 0.0 trxB1 1.8.1.9 C Thioredoxin domain
MIDIMPMF_00417 6.1e-307 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MIDIMPMF_00418 2.8e-238 yhjX EGP Major facilitator Superfamily
MIDIMPMF_00419 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MIDIMPMF_00420 0.0 yjjP S Threonine/Serine exporter, ThrE
MIDIMPMF_00421 4.2e-179 S Amidohydrolase family
MIDIMPMF_00422 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MIDIMPMF_00423 6.5e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIDIMPMF_00424 1e-47 S Protein of unknown function (DUF3073)
MIDIMPMF_00425 1.3e-88 K LytTr DNA-binding domain
MIDIMPMF_00426 2e-61 T protein histidine kinase activity
MIDIMPMF_00427 3.2e-194 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIDIMPMF_00428 1.1e-24 I transferase activity, transferring acyl groups other than amino-acyl groups
MIDIMPMF_00429 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
MIDIMPMF_00430 1.5e-172 rfbJ M Glycosyl transferase family 2
MIDIMPMF_00431 0.0
MIDIMPMF_00432 2.5e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIDIMPMF_00433 0.0 3.6.4.12 K Putative DNA-binding domain
MIDIMPMF_00434 1.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MIDIMPMF_00435 4.4e-45 L Transposase DDE domain
MIDIMPMF_00436 1.7e-16 L Transposase
MIDIMPMF_00437 1.8e-65 L HTH-like domain
MIDIMPMF_00438 6.4e-115 L PFAM Integrase catalytic
MIDIMPMF_00439 3.8e-66 L Transposase, Mutator family
MIDIMPMF_00440 2.5e-59 L Transposase, Mutator family
MIDIMPMF_00441 1.2e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIDIMPMF_00442 8.7e-131 rgpC U Transport permease protein
MIDIMPMF_00443 1.3e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
MIDIMPMF_00444 7.9e-293 S Tetratricopeptide repeat
MIDIMPMF_00445 0.0 rgpF M Rhamnan synthesis protein F
MIDIMPMF_00446 5.7e-194 M Glycosyltransferase like family 2
MIDIMPMF_00447 2.8e-201 1.1.1.22 M UDP binding domain
MIDIMPMF_00448 1.6e-41 L Integrase core domain protein
MIDIMPMF_00449 8e-239
MIDIMPMF_00450 2.1e-307 3.6.4.12 K Putative DNA-binding domain
MIDIMPMF_00451 5.2e-170 tnp7109-21 L Integrase core domain
MIDIMPMF_00452 8.8e-259 S Domain of unknown function (DUF4143)
MIDIMPMF_00453 2e-17 yccF S Inner membrane component domain
MIDIMPMF_00454 3.5e-12
MIDIMPMF_00455 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
MIDIMPMF_00456 1.1e-42 tnp7109-21 L Integrase core domain
MIDIMPMF_00457 7.4e-45 L Transposase
MIDIMPMF_00458 1.1e-37 V ATPases associated with a variety of cellular activities
MIDIMPMF_00459 1.5e-73 I Sterol carrier protein
MIDIMPMF_00460 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MIDIMPMF_00461 3.4e-35
MIDIMPMF_00462 2.7e-143 gluP 3.4.21.105 S Rhomboid family
MIDIMPMF_00463 1.4e-26 L HTH-like domain
MIDIMPMF_00464 4.7e-257 L ribosomal rna small subunit methyltransferase
MIDIMPMF_00465 2.6e-71 crgA D Involved in cell division
MIDIMPMF_00466 1e-142 S Bacterial protein of unknown function (DUF881)
MIDIMPMF_00467 6.8e-234 srtA 3.4.22.70 M Sortase family
MIDIMPMF_00468 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
MIDIMPMF_00469 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
MIDIMPMF_00470 2e-183 T Protein tyrosine kinase
MIDIMPMF_00471 4.8e-263 pbpA M penicillin-binding protein
MIDIMPMF_00472 2.8e-266 rodA D Belongs to the SEDS family
MIDIMPMF_00473 3.7e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
MIDIMPMF_00474 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
MIDIMPMF_00475 1e-130 fhaA T Protein of unknown function (DUF2662)
MIDIMPMF_00476 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
MIDIMPMF_00477 0.0 pip S YhgE Pip domain protein
MIDIMPMF_00478 0.0 pip S YhgE Pip domain protein
MIDIMPMF_00479 2.1e-207 pldB 3.1.1.5 I Serine aminopeptidase, S33
MIDIMPMF_00480 3.7e-166 yicL EG EamA-like transporter family
MIDIMPMF_00481 4.5e-103
MIDIMPMF_00483 6e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIDIMPMF_00485 0.0 KL Domain of unknown function (DUF3427)
MIDIMPMF_00486 2.5e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MIDIMPMF_00487 3.1e-34 D DivIVA domain protein
MIDIMPMF_00488 9.3e-53 ybjQ S Putative heavy-metal-binding
MIDIMPMF_00489 3.8e-156 I Serine aminopeptidase, S33
MIDIMPMF_00490 6.3e-87 yjcF Q Acetyltransferase (GNAT) domain
MIDIMPMF_00491 3.9e-50 L transposase activity
MIDIMPMF_00492 1.5e-53 tnp7109-21 L Integrase core domain
MIDIMPMF_00493 5.6e-42 tnp7109-21 L Integrase core domain
MIDIMPMF_00494 6.4e-16 L Phage integrase family
MIDIMPMF_00495 8.6e-13
MIDIMPMF_00497 3.2e-79 L HindVP restriction endonuclease
MIDIMPMF_00498 7e-116 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MIDIMPMF_00499 5.2e-33
MIDIMPMF_00500 1.1e-36 CP_0155 3.5.1.28 M LysM domain
MIDIMPMF_00501 2.6e-57 M Glycosyl hydrolases family 25
MIDIMPMF_00502 3.9e-15 2.7.7.7 L Transposase, Mutator family
MIDIMPMF_00504 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MIDIMPMF_00505 2.5e-243 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
MIDIMPMF_00506 0.0 cadA P E1-E2 ATPase
MIDIMPMF_00507 5e-273 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
MIDIMPMF_00508 9e-170 htpX O Belongs to the peptidase M48B family
MIDIMPMF_00510 8.5e-63 S Protein of unknown function DUF262
MIDIMPMF_00511 1.7e-84 S Protein of unknown function DUF262
MIDIMPMF_00512 1.1e-197
MIDIMPMF_00513 1.6e-80 S Nucleotidyltransferase domain
MIDIMPMF_00514 6.8e-69 K FR47-like protein
MIDIMPMF_00515 5.7e-41 S Polyketide cyclase / dehydrase and lipid transport
MIDIMPMF_00516 2.4e-84 S GyrI-like small molecule binding domain
MIDIMPMF_00517 3.1e-33 S Bacterial mobilisation protein (MobC)
MIDIMPMF_00518 2.8e-231 ltrBE1 U Relaxase/Mobilisation nuclease domain
MIDIMPMF_00519 2.9e-20
MIDIMPMF_00520 2.1e-249 3.5.1.104 G Polysaccharide deacetylase
MIDIMPMF_00521 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MIDIMPMF_00522 3.9e-68 S AAA ATPase domain
MIDIMPMF_00523 1.3e-10 V TIGR02646 family
MIDIMPMF_00524 3.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIDIMPMF_00525 7.4e-164 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIDIMPMF_00526 1.1e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIDIMPMF_00527 7.3e-197 K helix_turn _helix lactose operon repressor
MIDIMPMF_00528 6.5e-75 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
MIDIMPMF_00529 9.1e-298 scrT G Transporter major facilitator family protein
MIDIMPMF_00530 2.9e-254 yhjE EGP Sugar (and other) transporter
MIDIMPMF_00531 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIDIMPMF_00532 2e-202 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIDIMPMF_00533 1.6e-180 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
MIDIMPMF_00534 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MIDIMPMF_00535 1.3e-274 aroP E aromatic amino acid transport protein AroP K03293
MIDIMPMF_00536 7e-101 K Transcriptional regulator C-terminal region
MIDIMPMF_00537 2.6e-129 V ABC transporter
MIDIMPMF_00538 0.0 V FtsX-like permease family
MIDIMPMF_00539 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIDIMPMF_00540 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIDIMPMF_00541 7.6e-39 E ABC transporter
MIDIMPMF_00542 1.4e-98 bcp 1.11.1.15 O Redoxin
MIDIMPMF_00543 2.3e-149 S Virulence factor BrkB
MIDIMPMF_00544 2.1e-41 XAC3035 O Glutaredoxin
MIDIMPMF_00545 5.6e-66
MIDIMPMF_00547 2.1e-86
MIDIMPMF_00549 1.2e-26 M Belongs to the glycosyl hydrolase 30 family
MIDIMPMF_00550 5.8e-82 M Belongs to the glycosyl hydrolase 30 family
MIDIMPMF_00551 7.5e-191 1.1.1.65 C Aldo/keto reductase family
MIDIMPMF_00552 2.9e-93 ydgJ K helix_turn_helix multiple antibiotic resistance protein
MIDIMPMF_00553 0.0 lmrA1 V ABC transporter, ATP-binding protein
MIDIMPMF_00554 0.0 lmrA2 V ABC transporter transmembrane region
MIDIMPMF_00555 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
MIDIMPMF_00556 1.3e-107 S Phosphatidylethanolamine-binding protein
MIDIMPMF_00557 0.0 pepD E Peptidase family C69
MIDIMPMF_00558 2.9e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
MIDIMPMF_00559 1.3e-62 S Macrophage migration inhibitory factor (MIF)
MIDIMPMF_00560 2.6e-97 S GtrA-like protein
MIDIMPMF_00561 6.2e-263 EGP Major facilitator Superfamily
MIDIMPMF_00562 1.2e-125 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
MIDIMPMF_00563 5.1e-141
MIDIMPMF_00564 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
MIDIMPMF_00565 8.6e-201 P NMT1/THI5 like
MIDIMPMF_00566 1.9e-121 S HAD hydrolase, family IA, variant 3
MIDIMPMF_00568 1.3e-276 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIDIMPMF_00569 8e-99 S Domain of unknown function (DUF4143)
MIDIMPMF_00570 3.6e-45 S Domain of unknown function (DUF4143)
MIDIMPMF_00573 3.7e-251 S Calcineurin-like phosphoesterase
MIDIMPMF_00574 2.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
MIDIMPMF_00575 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIDIMPMF_00576 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIDIMPMF_00577 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
MIDIMPMF_00579 5.1e-180 S CAAX protease self-immunity
MIDIMPMF_00580 8.9e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
MIDIMPMF_00581 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIDIMPMF_00582 2.4e-224 G Transmembrane secretion effector
MIDIMPMF_00583 7.3e-132 K Bacterial regulatory proteins, tetR family
MIDIMPMF_00584 4.7e-126
MIDIMPMF_00585 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIDIMPMF_00586 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MIDIMPMF_00587 9.8e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
MIDIMPMF_00588 9.2e-187
MIDIMPMF_00589 2.3e-179
MIDIMPMF_00590 3.8e-163 trxA2 O Tetratricopeptide repeat
MIDIMPMF_00591 8.8e-121 cyaA 4.6.1.1 S CYTH
MIDIMPMF_00593 2e-183 K Bacterial regulatory proteins, lacI family
MIDIMPMF_00594 5.3e-18 4.2.1.68 M carboxylic acid catabolic process
MIDIMPMF_00595 6.7e-65 4.2.1.68 M Enolase C-terminal domain-like
MIDIMPMF_00596 6.8e-164 IQ KR domain
MIDIMPMF_00598 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MIDIMPMF_00599 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
MIDIMPMF_00600 5.4e-178 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MIDIMPMF_00601 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MIDIMPMF_00602 9.7e-305 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MIDIMPMF_00603 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MIDIMPMF_00604 1.3e-287 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
MIDIMPMF_00605 1.8e-240 hom 1.1.1.3 E Homoserine dehydrogenase
MIDIMPMF_00606 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MIDIMPMF_00607 1.1e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
MIDIMPMF_00608 2.9e-66
MIDIMPMF_00609 6.1e-58
MIDIMPMF_00610 4.9e-165 V ATPases associated with a variety of cellular activities
MIDIMPMF_00611 3.3e-256 V Efflux ABC transporter, permease protein
MIDIMPMF_00612 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
MIDIMPMF_00613 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
MIDIMPMF_00614 0.0 rne 3.1.26.12 J Ribonuclease E/G family
MIDIMPMF_00615 1.2e-46 rplU J This protein binds to 23S rRNA in the presence of protein L20
MIDIMPMF_00616 3.1e-40 rpmA J Ribosomal L27 protein
MIDIMPMF_00617 7.5e-216 K Psort location Cytoplasmic, score
MIDIMPMF_00618 3.7e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIDIMPMF_00619 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIDIMPMF_00620 2e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
MIDIMPMF_00622 1.8e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MIDIMPMF_00623 1.8e-116 nusG K Participates in transcription elongation, termination and antitermination
MIDIMPMF_00624 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
MIDIMPMF_00625 9.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MIDIMPMF_00626 8.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MIDIMPMF_00627 3.7e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MIDIMPMF_00628 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
MIDIMPMF_00629 1.5e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIDIMPMF_00630 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MIDIMPMF_00631 4.7e-118
MIDIMPMF_00632 2.8e-162 T Pfam Adenylate and Guanylate cyclase catalytic domain
MIDIMPMF_00633 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MIDIMPMF_00634 1.1e-79 ssb1 L Single-stranded DNA-binding protein
MIDIMPMF_00635 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MIDIMPMF_00636 6.6e-70 rplI J Binds to the 23S rRNA
MIDIMPMF_00637 4.1e-36 S Parallel beta-helix repeats
MIDIMPMF_00638 1e-69 E Domain of unknown function (DUF5011)
MIDIMPMF_00640 6.4e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MIDIMPMF_00641 7.4e-128 M Protein of unknown function (DUF3152)
MIDIMPMF_00642 3.1e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIDIMPMF_00643 6.5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIDIMPMF_00644 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
MIDIMPMF_00645 0.0 inlJ M domain protein
MIDIMPMF_00646 3.9e-282 M LPXTG cell wall anchor motif
MIDIMPMF_00647 8.5e-210 3.4.22.70 M Sortase family
MIDIMPMF_00648 8.5e-60 S Domain of unknown function (DUF4854)
MIDIMPMF_00649 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
MIDIMPMF_00650 8.7e-31 2.1.1.72 S Protein conserved in bacteria
MIDIMPMF_00651 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MIDIMPMF_00652 2.7e-132 M Mechanosensitive ion channel
MIDIMPMF_00653 1.7e-119 K Bacterial regulatory proteins, tetR family
MIDIMPMF_00654 2e-241 MA20_36090 S Psort location Cytoplasmic, score 8.87
MIDIMPMF_00655 4.2e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
MIDIMPMF_00656 1.3e-64
MIDIMPMF_00658 3e-41 K Transcriptional regulator
MIDIMPMF_00659 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MIDIMPMF_00660 3.5e-07 S Scramblase
MIDIMPMF_00661 1.6e-32
MIDIMPMF_00666 2e-109 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
MIDIMPMF_00667 1.9e-236 K Helix-turn-helix XRE-family like proteins
MIDIMPMF_00668 2.6e-52 relB L RelB antitoxin
MIDIMPMF_00669 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
MIDIMPMF_00670 2.5e-130 K helix_turn_helix, mercury resistance
MIDIMPMF_00671 6.6e-243 yxiO S Vacuole effluxer Atg22 like
MIDIMPMF_00673 1.1e-200 yegV G pfkB family carbohydrate kinase
MIDIMPMF_00674 1.4e-29 rpmB J Ribosomal L28 family
MIDIMPMF_00675 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
MIDIMPMF_00676 4.5e-220 steT E amino acid
MIDIMPMF_00679 0.0
MIDIMPMF_00680 3.8e-248 U Sodium:dicarboxylate symporter family
MIDIMPMF_00681 5.8e-121 rsmD 2.1.1.171 L Conserved hypothetical protein 95
MIDIMPMF_00682 2.9e-105 XK27_02070 S Nitroreductase family
MIDIMPMF_00683 8.9e-83 hsp20 O Hsp20/alpha crystallin family
MIDIMPMF_00684 1.4e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MIDIMPMF_00685 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIDIMPMF_00686 1.8e-34 CP_0960 S Belongs to the UPF0109 family
MIDIMPMF_00687 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MIDIMPMF_00689 2.9e-295 ydfD EK Alanine-glyoxylate amino-transferase
MIDIMPMF_00690 5.9e-94 argO S LysE type translocator
MIDIMPMF_00691 2.2e-221 S Endonuclease/Exonuclease/phosphatase family
MIDIMPMF_00692 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIDIMPMF_00693 1.4e-164 P Cation efflux family
MIDIMPMF_00694 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIDIMPMF_00695 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
MIDIMPMF_00696 0.0 yjjK S ABC transporter
MIDIMPMF_00697 2e-58 S Protein of unknown function (DUF3039)
MIDIMPMF_00698 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIDIMPMF_00699 1.5e-100
MIDIMPMF_00700 1e-113 yceD S Uncharacterized ACR, COG1399
MIDIMPMF_00701 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MIDIMPMF_00702 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MIDIMPMF_00703 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
MIDIMPMF_00704 7.6e-92 ilvN 2.2.1.6 E ACT domain
MIDIMPMF_00706 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIDIMPMF_00707 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIDIMPMF_00708 4.1e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIDIMPMF_00709 3.8e-174 S Auxin Efflux Carrier
MIDIMPMF_00712 0.0 pgi 5.3.1.9 G Belongs to the GPI family
MIDIMPMF_00713 1.5e-190
MIDIMPMF_00715 6.9e-201
MIDIMPMF_00717 3e-120 mgtC S MgtC family
MIDIMPMF_00718 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MIDIMPMF_00719 6.9e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MIDIMPMF_00720 1.4e-273 abcT3 P ATPases associated with a variety of cellular activities
MIDIMPMF_00721 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MIDIMPMF_00723 3.2e-30 K Putative sugar-binding domain
MIDIMPMF_00724 1.5e-96 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
MIDIMPMF_00725 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MIDIMPMF_00726 4.4e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MIDIMPMF_00727 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIDIMPMF_00728 4.4e-208 K helix_turn _helix lactose operon repressor
MIDIMPMF_00729 8.8e-11 fadD 6.2.1.3 I AMP-binding enzyme
MIDIMPMF_00730 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MIDIMPMF_00731 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MIDIMPMF_00732 1.1e-110 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MIDIMPMF_00735 7.1e-294 G Glycosyl hydrolases family 43
MIDIMPMF_00736 1.2e-200 K helix_turn _helix lactose operon repressor
MIDIMPMF_00737 2.4e-11 E Domain of unknown function (DUF5011)
MIDIMPMF_00738 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
MIDIMPMF_00739 2.9e-122 L Protein of unknown function (DUF1524)
MIDIMPMF_00740 5.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
MIDIMPMF_00741 1.5e-305 EGP Major facilitator Superfamily
MIDIMPMF_00742 5.8e-230
MIDIMPMF_00743 5e-179 S G5
MIDIMPMF_00744 2.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
MIDIMPMF_00745 1.5e-117 F Domain of unknown function (DUF4916)
MIDIMPMF_00746 1.4e-158 mhpC I Alpha/beta hydrolase family
MIDIMPMF_00747 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MIDIMPMF_00748 0.0 enhA_2 S L,D-transpeptidase catalytic domain
MIDIMPMF_00749 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MIDIMPMF_00750 1.1e-240 S Uncharacterized conserved protein (DUF2183)
MIDIMPMF_00751 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
MIDIMPMF_00752 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MIDIMPMF_00753 5.8e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
MIDIMPMF_00754 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
MIDIMPMF_00755 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MIDIMPMF_00756 3.7e-218 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
MIDIMPMF_00757 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MIDIMPMF_00758 3.1e-139 glpR K DeoR C terminal sensor domain
MIDIMPMF_00759 4.7e-251 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
MIDIMPMF_00760 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
MIDIMPMF_00761 8.6e-243 EGP Sugar (and other) transporter
MIDIMPMF_00762 4.2e-43 gcvR T Belongs to the UPF0237 family
MIDIMPMF_00763 9.4e-253 S UPF0210 protein
MIDIMPMF_00764 2.9e-108
MIDIMPMF_00765 1.9e-07 S Membrane
MIDIMPMF_00767 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MIDIMPMF_00768 4e-65 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MIDIMPMF_00769 7.8e-187 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
MIDIMPMF_00770 3.7e-106
MIDIMPMF_00771 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIDIMPMF_00772 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIDIMPMF_00773 1.3e-96 T Forkhead associated domain
MIDIMPMF_00774 6.9e-67 B Belongs to the OprB family
MIDIMPMF_00775 1.3e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
MIDIMPMF_00776 0.0 E Transglutaminase-like superfamily
MIDIMPMF_00777 2.8e-225 S Protein of unknown function DUF58
MIDIMPMF_00778 7.7e-228 S ATPase family associated with various cellular activities (AAA)
MIDIMPMF_00779 0.0 S Fibronectin type 3 domain
MIDIMPMF_00780 1.7e-268 KLT Protein tyrosine kinase
MIDIMPMF_00781 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MIDIMPMF_00782 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
MIDIMPMF_00783 2.6e-147 K -acetyltransferase
MIDIMPMF_00784 9.9e-250 G Major Facilitator Superfamily
MIDIMPMF_00785 2.7e-10 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MIDIMPMF_00786 6.4e-24 relB L RelB antitoxin
MIDIMPMF_00787 2.1e-57 L Transposase
MIDIMPMF_00788 2.2e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MIDIMPMF_00789 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIDIMPMF_00790 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIDIMPMF_00791 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
MIDIMPMF_00792 1.7e-251 O Subtilase family
MIDIMPMF_00793 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIDIMPMF_00794 8.8e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIDIMPMF_00795 1.4e-270 S zinc finger
MIDIMPMF_00796 4.1e-105 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MIDIMPMF_00797 2.9e-229 aspB E Aminotransferase class-V
MIDIMPMF_00798 2.3e-37 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MIDIMPMF_00799 5.4e-133 tmp1 S Domain of unknown function (DUF4391)
MIDIMPMF_00800 2.6e-149 moeB 2.7.7.80 H ThiF family
MIDIMPMF_00801 1.5e-253 cdr OP Sulfurtransferase TusA
MIDIMPMF_00802 2.8e-182 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MIDIMPMF_00805 6.2e-202 S Endonuclease/Exonuclease/phosphatase family
MIDIMPMF_00806 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIDIMPMF_00807 2.5e-272 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIDIMPMF_00808 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
MIDIMPMF_00809 1.2e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MIDIMPMF_00811 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
MIDIMPMF_00812 1.9e-164
MIDIMPMF_00813 1.5e-257 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
MIDIMPMF_00814 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
MIDIMPMF_00815 4.1e-87 K MarR family
MIDIMPMF_00816 0.0 V ABC transporter, ATP-binding protein
MIDIMPMF_00817 0.0 V ABC transporter transmembrane region
MIDIMPMF_00818 6.8e-168 S Patatin-like phospholipase
MIDIMPMF_00819 4.6e-154 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MIDIMPMF_00820 1.2e-168 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MIDIMPMF_00821 7.6e-115 S Vitamin K epoxide reductase
MIDIMPMF_00822 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
MIDIMPMF_00823 6.1e-32 S Protein of unknown function (DUF3107)
MIDIMPMF_00824 4.6e-245 mphA S Aminoglycoside phosphotransferase
MIDIMPMF_00825 2.8e-282 uvrD2 3.6.4.12 L DNA helicase
MIDIMPMF_00826 8.9e-284 S Zincin-like metallopeptidase
MIDIMPMF_00827 7.6e-152 lon T Belongs to the peptidase S16 family
MIDIMPMF_00828 5.7e-47 S Protein of unknown function (DUF3052)
MIDIMPMF_00829 1.2e-196 K helix_turn _helix lactose operon repressor
MIDIMPMF_00830 8e-61 S Thiamine-binding protein
MIDIMPMF_00831 6.6e-162 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MIDIMPMF_00832 6.9e-231 O AAA domain (Cdc48 subfamily)
MIDIMPMF_00833 1.3e-84
MIDIMPMF_00834 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MIDIMPMF_00835 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MIDIMPMF_00836 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
MIDIMPMF_00837 3.9e-300 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MIDIMPMF_00838 2.8e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIDIMPMF_00839 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIDIMPMF_00840 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MIDIMPMF_00841 2.1e-42 yggT S YGGT family
MIDIMPMF_00842 9.7e-90 3.1.21.3 V DivIVA protein
MIDIMPMF_00843 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIDIMPMF_00844 5.9e-69 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MIDIMPMF_00845 1.2e-96 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MIDIMPMF_00847 7.8e-63
MIDIMPMF_00848 2.6e-138 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MIDIMPMF_00849 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIDIMPMF_00850 1e-188 ftsE D Cell division ATP-binding protein FtsE
MIDIMPMF_00851 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
MIDIMPMF_00852 2.7e-157 usp 3.5.1.28 CBM50 D CHAP domain protein
MIDIMPMF_00853 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MIDIMPMF_00854 3e-147 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MIDIMPMF_00855 7.7e-45
MIDIMPMF_00856 3.3e-23
MIDIMPMF_00858 9.7e-201 2.7.11.1 NU Tfp pilus assembly protein FimV
MIDIMPMF_00859 5.2e-223 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MIDIMPMF_00860 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MIDIMPMF_00861 1.2e-291 I acetylesterase activity
MIDIMPMF_00862 2.1e-143 recO L Involved in DNA repair and RecF pathway recombination
MIDIMPMF_00863 1.8e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIDIMPMF_00864 1.5e-191 ywqG S Domain of unknown function (DUF1963)
MIDIMPMF_00865 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MIDIMPMF_00866 3e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MIDIMPMF_00867 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
MIDIMPMF_00868 7.3e-85 S zinc-ribbon domain
MIDIMPMF_00869 1.6e-46 yhbY J CRS1_YhbY
MIDIMPMF_00870 0.0 4.2.1.53 S MCRA family
MIDIMPMF_00873 8.9e-203 K WYL domain
MIDIMPMF_00874 1.3e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
MIDIMPMF_00875 1.1e-172 dkgA 1.1.1.346 C Aldo/keto reductase family
MIDIMPMF_00876 1.2e-76 yneG S Domain of unknown function (DUF4186)
MIDIMPMF_00878 3.9e-07 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MIDIMPMF_00879 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MIDIMPMF_00880 1.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIDIMPMF_00881 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIDIMPMF_00882 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
MIDIMPMF_00883 1.3e-112
MIDIMPMF_00884 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIDIMPMF_00885 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
MIDIMPMF_00886 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
MIDIMPMF_00887 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
MIDIMPMF_00888 5.9e-255 S Domain of unknown function (DUF5067)
MIDIMPMF_00889 7.9e-61 EGP Major facilitator Superfamily
MIDIMPMF_00890 6.7e-174 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MIDIMPMF_00891 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
MIDIMPMF_00892 2.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
MIDIMPMF_00893 3.9e-173
MIDIMPMF_00894 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIDIMPMF_00895 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
MIDIMPMF_00896 2.8e-163 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIDIMPMF_00897 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIDIMPMF_00898 1.1e-49 M Lysin motif
MIDIMPMF_00899 8.8e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIDIMPMF_00900 2.9e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MIDIMPMF_00901 0.0 L DNA helicase
MIDIMPMF_00902 1.3e-90 mraZ K Belongs to the MraZ family
MIDIMPMF_00903 9.2e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MIDIMPMF_00904 9.7e-64 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MIDIMPMF_00905 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
MIDIMPMF_00906 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIDIMPMF_00907 4e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MIDIMPMF_00908 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIDIMPMF_00909 1.6e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIDIMPMF_00910 4.3e-226 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
MIDIMPMF_00911 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MIDIMPMF_00912 8e-296 murC 6.3.2.8 M Belongs to the MurCDEF family
MIDIMPMF_00913 1.8e-157 ftsQ 6.3.2.4 D Cell division protein FtsQ
MIDIMPMF_00914 4.9e-37
MIDIMPMF_00916 1e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MIDIMPMF_00917 2.9e-235 G Major Facilitator Superfamily
MIDIMPMF_00918 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
MIDIMPMF_00919 1.6e-224 GK ROK family
MIDIMPMF_00920 9.9e-132 cutC P Participates in the control of copper homeostasis
MIDIMPMF_00921 1.6e-196 GK ROK family
MIDIMPMF_00922 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MIDIMPMF_00923 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
MIDIMPMF_00924 7.4e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
MIDIMPMF_00925 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
MIDIMPMF_00926 1.9e-190 dppC EP Binding-protein-dependent transport system inner membrane component
MIDIMPMF_00927 0.0 P Belongs to the ABC transporter superfamily
MIDIMPMF_00928 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
MIDIMPMF_00929 8.1e-96 3.6.1.55 F NUDIX domain
MIDIMPMF_00931 1.7e-288 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
MIDIMPMF_00932 0.0 smc D Required for chromosome condensation and partitioning
MIDIMPMF_00933 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MIDIMPMF_00934 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
MIDIMPMF_00935 3.4e-230 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
MIDIMPMF_00936 2e-191 V Acetyltransferase (GNAT) domain
MIDIMPMF_00937 1.2e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIDIMPMF_00938 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
MIDIMPMF_00939 5.8e-64
MIDIMPMF_00940 1.8e-194 galM 5.1.3.3 G Aldose 1-epimerase
MIDIMPMF_00941 5.5e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIDIMPMF_00943 3.2e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MIDIMPMF_00944 3.6e-199 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIDIMPMF_00945 3.4e-129 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
MIDIMPMF_00946 1.1e-37 S Spermine/spermidine synthase domain
MIDIMPMF_00947 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIDIMPMF_00948 2.1e-25 rpmI J Ribosomal protein L35
MIDIMPMF_00949 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIDIMPMF_00950 6.4e-179 xerD D recombinase XerD
MIDIMPMF_00951 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MIDIMPMF_00952 3.6e-149 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MIDIMPMF_00953 2.5e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIDIMPMF_00954 3.3e-149 nrtR 3.6.1.55 F NUDIX hydrolase
MIDIMPMF_00955 2.8e-251 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIDIMPMF_00956 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MIDIMPMF_00957 7e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
MIDIMPMF_00958 3.4e-236 iscS1 2.8.1.7 E Aminotransferase class-V
MIDIMPMF_00959 0.0 typA T Elongation factor G C-terminus
MIDIMPMF_00960 9.9e-81
MIDIMPMF_00961 1.7e-198 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
MIDIMPMF_00962 7.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
MIDIMPMF_00963 7.3e-42
MIDIMPMF_00964 8.6e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MIDIMPMF_00965 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
MIDIMPMF_00966 1.3e-165 dppC EP N-terminal TM domain of oligopeptide transport permease C
MIDIMPMF_00967 0.0 oppD P Belongs to the ABC transporter superfamily
MIDIMPMF_00968 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MIDIMPMF_00969 5.2e-262 pepC 3.4.22.40 E Peptidase C1-like family
MIDIMPMF_00970 4.8e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
MIDIMPMF_00971 2.1e-138 S Protein of unknown function (DUF3710)
MIDIMPMF_00972 9.8e-130 S Protein of unknown function (DUF3159)
MIDIMPMF_00973 1.1e-247 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIDIMPMF_00974 1.5e-109
MIDIMPMF_00975 0.0 ctpE P E1-E2 ATPase
MIDIMPMF_00976 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIDIMPMF_00978 1.1e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MIDIMPMF_00979 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
MIDIMPMF_00980 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MIDIMPMF_00981 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIDIMPMF_00982 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIDIMPMF_00984 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MIDIMPMF_00985 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIDIMPMF_00986 2.8e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
MIDIMPMF_00987 0.0 arc O AAA ATPase forming ring-shaped complexes
MIDIMPMF_00988 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
MIDIMPMF_00989 1.2e-157 hisN 3.1.3.25 G Inositol monophosphatase family
MIDIMPMF_00990 3.8e-09 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MIDIMPMF_00991 2.5e-275 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MIDIMPMF_00992 8.1e-42 hup L Belongs to the bacterial histone-like protein family
MIDIMPMF_00993 0.0 S Lysylphosphatidylglycerol synthase TM region
MIDIMPMF_00994 5e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
MIDIMPMF_00995 7.5e-291 S PGAP1-like protein
MIDIMPMF_00997 2.7e-74
MIDIMPMF_00998 1.6e-148 S von Willebrand factor (vWF) type A domain
MIDIMPMF_00999 4.4e-189 S von Willebrand factor (vWF) type A domain
MIDIMPMF_01000 1.4e-93
MIDIMPMF_01001 2.1e-177 S Protein of unknown function DUF58
MIDIMPMF_01002 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
MIDIMPMF_01003 3.5e-143 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIDIMPMF_01004 7.6e-71 S LytR cell envelope-related transcriptional attenuator
MIDIMPMF_01005 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
MIDIMPMF_01006 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MIDIMPMF_01007 1.7e-10 S Proteins of 100 residues with WXG
MIDIMPMF_01008 5.4e-169
MIDIMPMF_01009 2.1e-134 KT Response regulator receiver domain protein
MIDIMPMF_01010 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIDIMPMF_01011 1e-66 cspB K 'Cold-shock' DNA-binding domain
MIDIMPMF_01012 1.6e-202 S Protein of unknown function (DUF3027)
MIDIMPMF_01013 4.7e-185 uspA T Belongs to the universal stress protein A family
MIDIMPMF_01014 0.0 clpC O ATPase family associated with various cellular activities (AAA)
MIDIMPMF_01017 1.7e-56 2.7.13.3 T Histidine kinase
MIDIMPMF_01018 5.1e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MIDIMPMF_01019 2.4e-264 hisS 6.1.1.21 J Histidyl-tRNA synthetase
MIDIMPMF_01020 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIDIMPMF_01021 1.4e-63 K helix_turn_helix, Lux Regulon
MIDIMPMF_01022 5.3e-92 S Aminoacyl-tRNA editing domain
MIDIMPMF_01023 3.9e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
MIDIMPMF_01024 1.2e-146 gluB ET Belongs to the bacterial solute-binding protein 3 family
MIDIMPMF_01025 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
MIDIMPMF_01026 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
MIDIMPMF_01027 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
MIDIMPMF_01028 0.0 L DEAD DEAH box helicase
MIDIMPMF_01029 1.9e-256 rarA L Recombination factor protein RarA
MIDIMPMF_01031 1.2e-256 EGP Major facilitator Superfamily
MIDIMPMF_01032 0.0 ecfA GP ABC transporter, ATP-binding protein
MIDIMPMF_01033 9.6e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MIDIMPMF_01035 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
MIDIMPMF_01036 2e-213 E Aminotransferase class I and II
MIDIMPMF_01037 7.6e-138 bioM P ATPases associated with a variety of cellular activities
MIDIMPMF_01038 1.3e-60 2.8.2.22 S Arylsulfotransferase Ig-like domain
MIDIMPMF_01039 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIDIMPMF_01040 0.0 S Tetratricopeptide repeat
MIDIMPMF_01041 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIDIMPMF_01042 9.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MIDIMPMF_01043 5.7e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MIDIMPMF_01044 2e-86 int L Phage integrase, N-terminal SAM-like domain
MIDIMPMF_01045 6.3e-115 L DNA restriction-modification system
MIDIMPMF_01046 7.8e-33 3.1.21.4 L Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
MIDIMPMF_01047 5.2e-79 S GIY-YIG catalytic domain
MIDIMPMF_01051 5.5e-33 traSA D DNA segregation ATPase FtsK SpoIIIE
MIDIMPMF_01053 4.7e-10
MIDIMPMF_01054 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
MIDIMPMF_01055 3.6e-143 S Domain of unknown function (DUF4191)
MIDIMPMF_01056 5.2e-281 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIDIMPMF_01057 4.2e-104 S Protein of unknown function (DUF3043)
MIDIMPMF_01058 8.8e-259 argE E Peptidase dimerisation domain
MIDIMPMF_01059 3.4e-192 V N-Acetylmuramoyl-L-alanine amidase
MIDIMPMF_01060 6.5e-148 ytrE V ATPases associated with a variety of cellular activities
MIDIMPMF_01061 8.4e-196
MIDIMPMF_01062 2.3e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MIDIMPMF_01063 0.0 S Uncharacterised protein family (UPF0182)
MIDIMPMF_01064 8.1e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIDIMPMF_01065 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIDIMPMF_01066 2.4e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
MIDIMPMF_01069 9e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIDIMPMF_01070 2.1e-196 GM GDP-mannose 4,6 dehydratase
MIDIMPMF_01071 3.6e-151 GM ABC-2 type transporter
MIDIMPMF_01072 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
MIDIMPMF_01073 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
MIDIMPMF_01074 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MIDIMPMF_01075 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIDIMPMF_01076 2.2e-298 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
MIDIMPMF_01077 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
MIDIMPMF_01078 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MIDIMPMF_01079 2.5e-101 divIC D Septum formation initiator
MIDIMPMF_01080 9.8e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
MIDIMPMF_01081 9.8e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MIDIMPMF_01083 6.1e-97
MIDIMPMF_01084 1.1e-280 sdaA 4.3.1.17 E Serine dehydratase alpha chain
MIDIMPMF_01085 2.2e-72 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
MIDIMPMF_01086 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MIDIMPMF_01089 2.3e-107
MIDIMPMF_01090 2e-142 yplQ S Haemolysin-III related
MIDIMPMF_01091 2.8e-285 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIDIMPMF_01092 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MIDIMPMF_01093 0.0 D FtsK/SpoIIIE family
MIDIMPMF_01094 2.4e-270 K Cell envelope-related transcriptional attenuator domain
MIDIMPMF_01095 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MIDIMPMF_01096 0.0 S Glycosyl transferase, family 2
MIDIMPMF_01097 3.6e-261
MIDIMPMF_01098 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
MIDIMPMF_01099 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
MIDIMPMF_01100 1.4e-130 ctsW S Phosphoribosyl transferase domain
MIDIMPMF_01101 2.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
MIDIMPMF_01102 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MIDIMPMF_01103 1.9e-127 T Response regulator receiver domain protein
MIDIMPMF_01104 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MIDIMPMF_01105 5.1e-102 carD K CarD-like/TRCF domain
MIDIMPMF_01106 9.4e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MIDIMPMF_01107 4.3e-139 znuB U ABC 3 transport family
MIDIMPMF_01108 1.8e-164 znuC P ATPases associated with a variety of cellular activities
MIDIMPMF_01109 1.5e-173 P Zinc-uptake complex component A periplasmic
MIDIMPMF_01110 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIDIMPMF_01111 3.3e-243 rpsA J Ribosomal protein S1
MIDIMPMF_01112 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MIDIMPMF_01113 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MIDIMPMF_01114 1.7e-179 terC P Integral membrane protein, TerC family
MIDIMPMF_01115 4.8e-271 pyk 2.7.1.40 G Pyruvate kinase
MIDIMPMF_01116 1.8e-110 aspA 3.6.1.13 L NUDIX domain
MIDIMPMF_01118 9.2e-120 pdtaR T Response regulator receiver domain protein
MIDIMPMF_01119 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIDIMPMF_01120 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
MIDIMPMF_01121 1.9e-127 3.6.1.13 L NUDIX domain
MIDIMPMF_01122 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MIDIMPMF_01123 3.2e-220 ykiI
MIDIMPMF_01125 1.7e-136 L Phage integrase family
MIDIMPMF_01126 2.9e-108 3.4.13.21 E Peptidase family S51
MIDIMPMF_01127 1.7e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MIDIMPMF_01128 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MIDIMPMF_01129 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MIDIMPMF_01130 2.1e-25 L Transposase
MIDIMPMF_01131 2.9e-88 L Transposase
MIDIMPMF_01132 4.5e-85
MIDIMPMF_01133 9.9e-112 bepIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
MIDIMPMF_01134 2.3e-115 L HTH-like domain
MIDIMPMF_01135 2e-101 L PFAM Integrase catalytic
MIDIMPMF_01136 3e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MIDIMPMF_01137 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MIDIMPMF_01138 6.8e-190 pit P Phosphate transporter family
MIDIMPMF_01139 1.1e-115 MA20_27875 P Protein of unknown function DUF47
MIDIMPMF_01140 1.4e-122 K helix_turn_helix, Lux Regulon
MIDIMPMF_01141 5.8e-236 T Histidine kinase
MIDIMPMF_01142 4e-43 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MIDIMPMF_01143 1.2e-185 V ATPases associated with a variety of cellular activities
MIDIMPMF_01144 5.3e-226 V ABC-2 family transporter protein
MIDIMPMF_01145 1.3e-252 V ABC-2 family transporter protein
MIDIMPMF_01146 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MIDIMPMF_01147 1e-201 L Transposase and inactivated derivatives IS30 family
MIDIMPMF_01149 3e-78
MIDIMPMF_01150 1.2e-64 D MobA/MobL family
MIDIMPMF_01151 8.6e-48 L Transposase
MIDIMPMF_01152 1.3e-176 tnp7109-21 L Integrase core domain
MIDIMPMF_01153 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
MIDIMPMF_01154 9e-40
MIDIMPMF_01155 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
MIDIMPMF_01157 1.7e-44 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MIDIMPMF_01159 6.3e-241 pbuX F Permease family
MIDIMPMF_01160 3e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MIDIMPMF_01161 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
MIDIMPMF_01162 0.0 pcrA 3.6.4.12 L DNA helicase
MIDIMPMF_01163 1.8e-63 S Domain of unknown function (DUF4418)
MIDIMPMF_01164 3.8e-213 V FtsX-like permease family
MIDIMPMF_01165 4.3e-128 lolD V ABC transporter
MIDIMPMF_01166 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MIDIMPMF_01167 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
MIDIMPMF_01168 6.5e-136 pgm3 G Phosphoglycerate mutase family
MIDIMPMF_01169 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
MIDIMPMF_01170 1.1e-36
MIDIMPMF_01171 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIDIMPMF_01172 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIDIMPMF_01173 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIDIMPMF_01174 1.3e-47 3.4.23.43 S Type IV leader peptidase family
MIDIMPMF_01175 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIDIMPMF_01176 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIDIMPMF_01177 5.9e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MIDIMPMF_01178 1.9e-75
MIDIMPMF_01179 1.7e-120 K helix_turn_helix, Lux Regulon
MIDIMPMF_01180 1.3e-06 M Sortase family
MIDIMPMF_01181 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MIDIMPMF_01182 3.6e-290 sufB O FeS assembly protein SufB
MIDIMPMF_01183 5.7e-233 sufD O FeS assembly protein SufD
MIDIMPMF_01184 1.4e-144 sufC O FeS assembly ATPase SufC
MIDIMPMF_01185 1e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIDIMPMF_01186 1.5e-100 iscU C SUF system FeS assembly protein, NifU family
MIDIMPMF_01187 1.2e-108 yitW S Iron-sulfur cluster assembly protein
MIDIMPMF_01188 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MIDIMPMF_01189 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
MIDIMPMF_01191 7.2e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MIDIMPMF_01192 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
MIDIMPMF_01193 3.4e-197 phoH T PhoH-like protein
MIDIMPMF_01194 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIDIMPMF_01195 2.4e-251 corC S CBS domain
MIDIMPMF_01196 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIDIMPMF_01197 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MIDIMPMF_01198 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
MIDIMPMF_01199 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
MIDIMPMF_01200 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIDIMPMF_01201 4.8e-190 S alpha beta
MIDIMPMF_01202 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIDIMPMF_01203 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
MIDIMPMF_01204 4e-46 S phosphoesterase or phosphohydrolase
MIDIMPMF_01205 2.7e-99 3.1.4.37 T RNA ligase
MIDIMPMF_01206 1.2e-135 S UPF0126 domain
MIDIMPMF_01207 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
MIDIMPMF_01208 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MIDIMPMF_01209 6e-247 hemN H Involved in the biosynthesis of porphyrin-containing compound
MIDIMPMF_01210 4e-13 S Membrane
MIDIMPMF_01211 8.2e-293 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
MIDIMPMF_01212 0.0 tetP J Elongation factor G, domain IV
MIDIMPMF_01213 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
MIDIMPMF_01214 1e-303 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MIDIMPMF_01215 3.6e-82
MIDIMPMF_01216 8.7e-245 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
MIDIMPMF_01217 8.9e-164 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
MIDIMPMF_01218 1.7e-151 ybeM S Carbon-nitrogen hydrolase
MIDIMPMF_01219 3e-50 S Sel1-like repeats.
MIDIMPMF_01220 2.6e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MIDIMPMF_01221 2.1e-163 L Transposase
MIDIMPMF_01222 1.6e-28
MIDIMPMF_01223 8.4e-222 L Uncharacterized conserved protein (DUF2075)
MIDIMPMF_01224 2.8e-28
MIDIMPMF_01225 1.3e-97 rarD 3.4.17.13 E Rard protein
MIDIMPMF_01226 3.3e-177 I alpha/beta hydrolase fold
MIDIMPMF_01227 1.3e-207 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIDIMPMF_01228 2.6e-100 sixA T Phosphoglycerate mutase family
MIDIMPMF_01229 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIDIMPMF_01230 2.1e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
MIDIMPMF_01232 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MIDIMPMF_01233 6.4e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MIDIMPMF_01234 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MIDIMPMF_01235 2.9e-281 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MIDIMPMF_01236 2.2e-179 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
MIDIMPMF_01237 2.3e-153 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MIDIMPMF_01238 2.8e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MIDIMPMF_01239 6.5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIDIMPMF_01240 1e-16 K MerR family regulatory protein
MIDIMPMF_01241 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MIDIMPMF_01242 6.8e-119
MIDIMPMF_01244 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIDIMPMF_01245 4.4e-242 vbsD V MatE
MIDIMPMF_01246 2.1e-131 S Enoyl-(Acyl carrier protein) reductase
MIDIMPMF_01247 2.3e-133 magIII L endonuclease III
MIDIMPMF_01248 5e-93 laaE K Transcriptional regulator PadR-like family
MIDIMPMF_01249 4.4e-175 S Membrane transport protein
MIDIMPMF_01250 6.2e-66 4.1.1.44 S Cupin domain
MIDIMPMF_01251 2.7e-224 hipA 2.7.11.1 S HipA N-terminal domain
MIDIMPMF_01252 1.4e-40 K Helix-turn-helix
MIDIMPMF_01253 3.1e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
MIDIMPMF_01254 1.6e-18
MIDIMPMF_01255 9.3e-101 K Bacterial regulatory proteins, tetR family
MIDIMPMF_01256 2e-91 T Domain of unknown function (DUF4234)
MIDIMPMF_01257 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
MIDIMPMF_01258 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MIDIMPMF_01259 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIDIMPMF_01260 5.8e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
MIDIMPMF_01261 7.3e-89 dkgB S Oxidoreductase, aldo keto reductase family protein
MIDIMPMF_01263 4.8e-287 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
MIDIMPMF_01264 0.0 pafB K WYL domain
MIDIMPMF_01265 7e-53
MIDIMPMF_01266 0.0 helY L DEAD DEAH box helicase
MIDIMPMF_01267 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MIDIMPMF_01268 7.3e-143 pgp 3.1.3.18 S HAD-hyrolase-like
MIDIMPMF_01271 6.2e-90 K Putative zinc ribbon domain
MIDIMPMF_01272 7.2e-126 S GyrI-like small molecule binding domain
MIDIMPMF_01273 5e-96 L DNA integration
MIDIMPMF_01275 1.9e-62
MIDIMPMF_01276 5.2e-119 K helix_turn_helix, mercury resistance
MIDIMPMF_01277 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
MIDIMPMF_01278 3.4e-141 S Bacterial protein of unknown function (DUF881)
MIDIMPMF_01279 2.6e-31 sbp S Protein of unknown function (DUF1290)
MIDIMPMF_01280 4e-173 S Bacterial protein of unknown function (DUF881)
MIDIMPMF_01281 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIDIMPMF_01282 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
MIDIMPMF_01283 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
MIDIMPMF_01284 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
MIDIMPMF_01285 2.3e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIDIMPMF_01286 9.2e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MIDIMPMF_01287 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MIDIMPMF_01288 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
MIDIMPMF_01289 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MIDIMPMF_01290 5.3e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MIDIMPMF_01291 5.7e-30
MIDIMPMF_01292 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MIDIMPMF_01293 5e-246
MIDIMPMF_01294 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIDIMPMF_01295 1.9e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MIDIMPMF_01296 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIDIMPMF_01297 2.6e-44 yajC U Preprotein translocase subunit
MIDIMPMF_01298 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MIDIMPMF_01299 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MIDIMPMF_01300 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MIDIMPMF_01301 1e-131 yebC K transcriptional regulatory protein
MIDIMPMF_01302 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
MIDIMPMF_01303 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIDIMPMF_01304 1.3e-245 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIDIMPMF_01307 1.4e-260
MIDIMPMF_01311 2.8e-156 S PAC2 family
MIDIMPMF_01312 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MIDIMPMF_01313 7.1e-160 G Fructosamine kinase
MIDIMPMF_01314 1.3e-210 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MIDIMPMF_01315 1.5e-204 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MIDIMPMF_01316 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
MIDIMPMF_01317 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIDIMPMF_01318 1.2e-143 yoaK S Protein of unknown function (DUF1275)
MIDIMPMF_01319 3.7e-252 brnQ U Component of the transport system for branched-chain amino acids
MIDIMPMF_01321 5.2e-243 mepA_6 V MatE
MIDIMPMF_01322 8e-162 S Sucrose-6F-phosphate phosphohydrolase
MIDIMPMF_01323 3.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MIDIMPMF_01324 8e-33 secG U Preprotein translocase SecG subunit
MIDIMPMF_01325 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MIDIMPMF_01326 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
MIDIMPMF_01327 4.5e-172 whiA K May be required for sporulation
MIDIMPMF_01328 2.6e-177 rapZ S Displays ATPase and GTPase activities
MIDIMPMF_01329 7e-178 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
MIDIMPMF_01330 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MIDIMPMF_01331 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MIDIMPMF_01332 1e-76
MIDIMPMF_01333 1.8e-58 V MacB-like periplasmic core domain
MIDIMPMF_01334 3.3e-118 K Transcriptional regulatory protein, C terminal
MIDIMPMF_01335 5.1e-233 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MIDIMPMF_01336 2.2e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MIDIMPMF_01337 7.6e-302 ybiT S ABC transporter
MIDIMPMF_01338 1.4e-197 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MIDIMPMF_01339 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MIDIMPMF_01340 6.2e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
MIDIMPMF_01341 2.7e-216 GK ROK family
MIDIMPMF_01342 6.9e-178 2.7.1.2 GK ROK family
MIDIMPMF_01343 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MIDIMPMF_01344 5.5e-167 G ABC transporter permease
MIDIMPMF_01345 1.4e-173 G Binding-protein-dependent transport system inner membrane component
MIDIMPMF_01346 6.5e-243 G Bacterial extracellular solute-binding protein
MIDIMPMF_01347 1.8e-303 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIDIMPMF_01348 2e-73 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MIDIMPMF_01349 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MIDIMPMF_01350 8.3e-229 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MIDIMPMF_01351 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
MIDIMPMF_01352 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MIDIMPMF_01353 7e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MIDIMPMF_01354 1e-127 3.2.1.8 S alpha beta
MIDIMPMF_01355 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIDIMPMF_01356 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
MIDIMPMF_01357 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIDIMPMF_01358 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
MIDIMPMF_01359 3.4e-91
MIDIMPMF_01360 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
MIDIMPMF_01361 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
MIDIMPMF_01362 3.2e-276 G ABC transporter substrate-binding protein
MIDIMPMF_01363 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
MIDIMPMF_01364 2.2e-132 M Peptidase family M23
MIDIMPMF_01366 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIDIMPMF_01367 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
MIDIMPMF_01368 1e-156 yeaZ 2.3.1.234 O Glycoprotease family
MIDIMPMF_01369 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
MIDIMPMF_01370 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
MIDIMPMF_01371 0.0 comE S Competence protein
MIDIMPMF_01372 3.1e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
MIDIMPMF_01373 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIDIMPMF_01374 2e-169 ET Bacterial periplasmic substrate-binding proteins
MIDIMPMF_01375 9.9e-169 corA P CorA-like Mg2+ transporter protein
MIDIMPMF_01376 1.8e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MIDIMPMF_01377 5.9e-299 E Serine carboxypeptidase
MIDIMPMF_01378 0.0 S Psort location Cytoplasmic, score 8.87
MIDIMPMF_01379 2.8e-116 S Domain of unknown function (DUF4194)
MIDIMPMF_01380 8.8e-284 S Psort location Cytoplasmic, score 8.87
MIDIMPMF_01381 2.5e-163 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MIDIMPMF_01382 1.5e-64 yeaO K Protein of unknown function, DUF488
MIDIMPMF_01383 1.2e-120 ydaF_1 J Acetyltransferase (GNAT) domain
MIDIMPMF_01384 1.2e-97 MA20_25245 K FR47-like protein
MIDIMPMF_01385 4.3e-56 K Transcriptional regulator
MIDIMPMF_01386 2.1e-33 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
MIDIMPMF_01387 2.7e-38 J Aminoacyl-tRNA editing domain
MIDIMPMF_01388 5.4e-186 S Acetyltransferase (GNAT) domain
MIDIMPMF_01389 1.1e-29 L Transposase
MIDIMPMF_01390 9.4e-132 S SOS response associated peptidase (SRAP)
MIDIMPMF_01391 4.8e-128
MIDIMPMF_01392 1.6e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIDIMPMF_01393 2.2e-163 rpoC M heme binding
MIDIMPMF_01394 3.4e-118 EGP Major facilitator Superfamily
MIDIMPMF_01396 1.2e-158
MIDIMPMF_01397 1.9e-95 ypjC S Putative ABC-transporter type IV
MIDIMPMF_01398 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
MIDIMPMF_01399 2.2e-193 V VanZ like family
MIDIMPMF_01400 2.7e-146 KT RESPONSE REGULATOR receiver
MIDIMPMF_01401 2.7e-70 pdxH S Pfam:Pyridox_oxidase
MIDIMPMF_01402 5.6e-142 yijF S Domain of unknown function (DUF1287)
MIDIMPMF_01403 5e-133 C Putative TM nitroreductase
MIDIMPMF_01404 3e-93
MIDIMPMF_01406 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
MIDIMPMF_01407 1.3e-78 S Bacterial PH domain
MIDIMPMF_01408 1.1e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MIDIMPMF_01409 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MIDIMPMF_01410 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIDIMPMF_01412 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIDIMPMF_01413 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIDIMPMF_01414 5.2e-93
MIDIMPMF_01415 2e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIDIMPMF_01416 1.7e-284 thrC 4.2.3.1 E Threonine synthase N terminus
MIDIMPMF_01417 4e-122 S ABC-2 family transporter protein
MIDIMPMF_01418 1.8e-125 S ABC-2 family transporter protein
MIDIMPMF_01419 2e-177 V ATPases associated with a variety of cellular activities
MIDIMPMF_01420 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
MIDIMPMF_01421 8.9e-124 S Haloacid dehalogenase-like hydrolase
MIDIMPMF_01422 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
MIDIMPMF_01423 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIDIMPMF_01424 3.3e-235 trkB P Cation transport protein
MIDIMPMF_01425 6.8e-116 trkA P TrkA-N domain
MIDIMPMF_01426 6.4e-101
MIDIMPMF_01427 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MIDIMPMF_01429 3.3e-189 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MIDIMPMF_01430 8.3e-157 L Tetratricopeptide repeat
MIDIMPMF_01432 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIDIMPMF_01433 1.6e-143 S Putative ABC-transporter type IV
MIDIMPMF_01434 6.1e-108 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MIDIMPMF_01435 3.1e-281 argH 4.3.2.1 E argininosuccinate lyase
MIDIMPMF_01436 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MIDIMPMF_01437 9.7e-278 K Putative DNA-binding domain
MIDIMPMF_01438 3.8e-107 3.1.21.3 V type I restriction modification DNA specificity domain
MIDIMPMF_01439 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
MIDIMPMF_01440 2.9e-156 S Domain of unknown function (DUF4357)
MIDIMPMF_01441 2.4e-30
MIDIMPMF_01442 1e-178 L Phage integrase family
MIDIMPMF_01443 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MIDIMPMF_01444 1.4e-84 argR K Regulates arginine biosynthesis genes
MIDIMPMF_01445 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIDIMPMF_01446 2.8e-246 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MIDIMPMF_01447 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MIDIMPMF_01448 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIDIMPMF_01449 5.9e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIDIMPMF_01450 1.4e-89
MIDIMPMF_01451 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
MIDIMPMF_01452 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIDIMPMF_01453 2.3e-159 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIDIMPMF_01454 1.9e-133 ybbL V ATPases associated with a variety of cellular activities
MIDIMPMF_01455 9.3e-136 ybbM V Uncharacterised protein family (UPF0014)
MIDIMPMF_01456 3e-53 IQ oxidoreductase activity
MIDIMPMF_01458 7.5e-77 K AraC-like ligand binding domain
MIDIMPMF_01459 5.2e-237 rutG F Permease family
MIDIMPMF_01460 8.9e-158 3.1.3.73 G Phosphoglycerate mutase family
MIDIMPMF_01461 1.6e-54 estB S Phospholipase/Carboxylesterase
MIDIMPMF_01462 3.2e-187 MA20_14895 S Conserved hypothetical protein 698
MIDIMPMF_01463 1.5e-144 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
MIDIMPMF_01464 2.9e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
MIDIMPMF_01465 1.2e-291 2.4.1.166 GT2 M Glycosyltransferase like family 2
MIDIMPMF_01467 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MIDIMPMF_01468 3e-124 ypfH S Phospholipase/Carboxylesterase
MIDIMPMF_01469 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MIDIMPMF_01471 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MIDIMPMF_01472 2.8e-66 S Zincin-like metallopeptidase
MIDIMPMF_01473 2.7e-87 S Helix-turn-helix
MIDIMPMF_01474 5.5e-199 S Short C-terminal domain
MIDIMPMF_01475 2.7e-22
MIDIMPMF_01476 6.1e-132
MIDIMPMF_01478 4.5e-79 K Psort location Cytoplasmic, score
MIDIMPMF_01479 3.2e-255 KLT Protein tyrosine kinase
MIDIMPMF_01480 7.9e-66 S Cupin 2, conserved barrel domain protein
MIDIMPMF_01481 5.2e-156 ksgA 2.1.1.182 J Methyltransferase domain
MIDIMPMF_01482 5.6e-59 yccF S Inner membrane component domain
MIDIMPMF_01483 4.7e-118 E Psort location Cytoplasmic, score 8.87
MIDIMPMF_01484 1.1e-245 XK27_00240 K Fic/DOC family
MIDIMPMF_01485 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MIDIMPMF_01486 4.4e-230 mtnE 2.6.1.83 E Aminotransferase class I and II
MIDIMPMF_01487 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
MIDIMPMF_01488 3e-204 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIDIMPMF_01489 2.3e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MIDIMPMF_01490 3.8e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
MIDIMPMF_01491 4.2e-147 P NLPA lipoprotein
MIDIMPMF_01492 3.4e-169 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
MIDIMPMF_01493 1.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIDIMPMF_01494 6.5e-265 pip 3.4.11.5 S alpha/beta hydrolase fold
MIDIMPMF_01495 0.0 tcsS2 T Histidine kinase
MIDIMPMF_01496 6.1e-132 K helix_turn_helix, Lux Regulon
MIDIMPMF_01497 0.0 phoN I PAP2 superfamily
MIDIMPMF_01498 0.0 MV MacB-like periplasmic core domain
MIDIMPMF_01499 4e-162 V ABC transporter, ATP-binding protein
MIDIMPMF_01500 7.7e-252 metY 2.5.1.49 E Aminotransferase class-V
MIDIMPMF_01501 7.9e-157 S Putative ABC-transporter type IV
MIDIMPMF_01502 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MIDIMPMF_01503 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
MIDIMPMF_01504 6.5e-57 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
MIDIMPMF_01505 2.9e-279 dprA 5.99.1.2 LU DNA recombination-mediator protein A
MIDIMPMF_01506 2.7e-293 comM O Magnesium chelatase, subunit ChlI C-terminal
MIDIMPMF_01507 3e-71 yraN L Belongs to the UPF0102 family
MIDIMPMF_01508 1.9e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
MIDIMPMF_01509 1.1e-118 safC S O-methyltransferase
MIDIMPMF_01510 9.3e-167 fmt2 3.2.2.10 S Belongs to the LOG family
MIDIMPMF_01511 5.9e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIDIMPMF_01512 2.9e-234 patB 4.4.1.8 E Aminotransferase, class I II
MIDIMPMF_01515 2.9e-243 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIDIMPMF_01516 9.4e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIDIMPMF_01517 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIDIMPMF_01519 1.2e-250 clcA_2 P Voltage gated chloride channel
MIDIMPMF_01520 3.4e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MIDIMPMF_01521 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
MIDIMPMF_01522 1.3e-113 S Protein of unknown function (DUF3000)
MIDIMPMF_01523 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MIDIMPMF_01524 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MIDIMPMF_01525 3.4e-48
MIDIMPMF_01526 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIDIMPMF_01527 2.7e-224 S Peptidase dimerisation domain
MIDIMPMF_01528 1.4e-84 P ABC-type metal ion transport system permease component
MIDIMPMF_01529 1.4e-166 S Sucrose-6F-phosphate phosphohydrolase
MIDIMPMF_01530 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIDIMPMF_01531 1.1e-49 relB L RelB antitoxin
MIDIMPMF_01532 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
MIDIMPMF_01533 1.3e-207 E Belongs to the peptidase S1B family
MIDIMPMF_01534 3.1e-34
MIDIMPMF_01535 2.4e-205 S HipA-like C-terminal domain
MIDIMPMF_01536 2e-232 hsdM 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
MIDIMPMF_01537 4.6e-73 S EcsC protein family
MIDIMPMF_01539 3.7e-26 L DNA integration
MIDIMPMF_01540 3.3e-26
MIDIMPMF_01541 2.5e-141 fic D Fic/DOC family
MIDIMPMF_01542 1.8e-232 L Phage integrase family
MIDIMPMF_01543 1.1e-244 L Transposase
MIDIMPMF_01544 4.7e-137 L IstB-like ATP binding protein
MIDIMPMF_01545 2.7e-28
MIDIMPMF_01546 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIDIMPMF_01547 8.5e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MIDIMPMF_01548 1.4e-47 S Domain of unknown function (DUF4193)
MIDIMPMF_01549 9.2e-171 S Protein of unknown function (DUF3071)
MIDIMPMF_01550 8.6e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
MIDIMPMF_01551 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MIDIMPMF_01552 0.0 lhr L DEAD DEAH box helicase
MIDIMPMF_01553 6.6e-25 yozG K Cro/C1-type HTH DNA-binding domain
MIDIMPMF_01554 8.6e-10 G Major Facilitator Superfamily
MIDIMPMF_01555 4.4e-277 aspA 4.3.1.1 E Fumarase C C-terminus
MIDIMPMF_01556 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MIDIMPMF_01557 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MIDIMPMF_01558 1.1e-121
MIDIMPMF_01559 1.4e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
MIDIMPMF_01560 0.0 pknL 2.7.11.1 KLT PASTA
MIDIMPMF_01561 5.1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
MIDIMPMF_01562 1.1e-107
MIDIMPMF_01563 3.5e-191 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIDIMPMF_01564 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MIDIMPMF_01565 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIDIMPMF_01566 1e-07
MIDIMPMF_01567 3.5e-73 recX S Modulates RecA activity
MIDIMPMF_01568 4e-215 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIDIMPMF_01569 7e-39 S Protein of unknown function (DUF3046)
MIDIMPMF_01570 7.3e-81 K Helix-turn-helix XRE-family like proteins
MIDIMPMF_01571 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
MIDIMPMF_01572 2e-123 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIDIMPMF_01573 0.0 ftsK D FtsK SpoIIIE family protein
MIDIMPMF_01574 1.2e-137 fic D Fic/DOC family
MIDIMPMF_01575 1.2e-184 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIDIMPMF_01576 2.8e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MIDIMPMF_01577 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
MIDIMPMF_01578 1.3e-168 ydeD EG EamA-like transporter family
MIDIMPMF_01579 1.1e-131 ybhL S Belongs to the BI1 family
MIDIMPMF_01580 1e-97 S Domain of unknown function (DUF5067)
MIDIMPMF_01581 3.6e-263 T Histidine kinase
MIDIMPMF_01582 1.1e-116 K helix_turn_helix, Lux Regulon
MIDIMPMF_01583 0.0 S Protein of unknown function DUF262
MIDIMPMF_01584 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MIDIMPMF_01585 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MIDIMPMF_01586 1.2e-238 carA 6.3.5.5 F Belongs to the CarA family
MIDIMPMF_01587 7.3e-89 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIDIMPMF_01588 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIDIMPMF_01590 2.7e-192 EGP Transmembrane secretion effector
MIDIMPMF_01591 0.0 S Esterase-like activity of phytase
MIDIMPMF_01592 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIDIMPMF_01593 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIDIMPMF_01594 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MIDIMPMF_01595 2.1e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIDIMPMF_01597 5.9e-199 ltaE 4.1.2.48 E Beta-eliminating lyase
MIDIMPMF_01598 4.1e-228 M Glycosyl transferase 4-like domain
MIDIMPMF_01599 0.0 M Parallel beta-helix repeats
MIDIMPMF_01600 3.5e-233 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MIDIMPMF_01601 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MIDIMPMF_01602 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
MIDIMPMF_01603 3.3e-110
MIDIMPMF_01604 6.4e-95 S Protein of unknown function (DUF4230)
MIDIMPMF_01605 5.8e-149 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
MIDIMPMF_01606 4.4e-32 K DNA-binding transcription factor activity
MIDIMPMF_01607 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIDIMPMF_01608 2e-32
MIDIMPMF_01609 8.9e-303 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
MIDIMPMF_01610 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIDIMPMF_01611 6.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MIDIMPMF_01612 5e-240 purD 6.3.4.13 F Belongs to the GARS family
MIDIMPMF_01613 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MIDIMPMF_01614 5.1e-246 S Putative esterase
MIDIMPMF_01615 0.0 lysX S Uncharacterised conserved protein (DUF2156)
MIDIMPMF_01616 1.5e-161 P Zinc-uptake complex component A periplasmic
MIDIMPMF_01617 2.8e-137 S cobalamin synthesis protein
MIDIMPMF_01618 2.6e-46 rpmB J Ribosomal L28 family
MIDIMPMF_01619 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIDIMPMF_01620 8.2e-41 rpmE2 J Ribosomal protein L31
MIDIMPMF_01621 8.2e-15 rpmJ J Ribosomal protein L36
MIDIMPMF_01622 1.9e-22 J Ribosomal L32p protein family
MIDIMPMF_01623 1.3e-175 ycgR S Predicted permease
MIDIMPMF_01624 2.2e-153 S TIGRFAM TIGR03943 family protein
MIDIMPMF_01625 9.8e-45
MIDIMPMF_01626 5.6e-73 zur P Belongs to the Fur family
MIDIMPMF_01627 2.4e-228 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIDIMPMF_01628 1.4e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIDIMPMF_01629 2.2e-179 adh3 C Zinc-binding dehydrogenase
MIDIMPMF_01630 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MIDIMPMF_01632 1.4e-44 S Memo-like protein
MIDIMPMF_01633 5.8e-230 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MIDIMPMF_01634 2.7e-160 K Helix-turn-helix domain, rpiR family
MIDIMPMF_01635 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MIDIMPMF_01636 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
MIDIMPMF_01637 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIDIMPMF_01638 3.4e-269 yhdG E aromatic amino acid transport protein AroP K03293
MIDIMPMF_01639 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIDIMPMF_01640 1.1e-10 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MIDIMPMF_01641 3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MIDIMPMF_01642 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MIDIMPMF_01643 3.8e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MIDIMPMF_01644 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
MIDIMPMF_01645 4.4e-109
MIDIMPMF_01646 2.1e-188 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIDIMPMF_01647 4.4e-155 sapF E ATPases associated with a variety of cellular activities
MIDIMPMF_01648 4e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
MIDIMPMF_01649 2e-164 EP Binding-protein-dependent transport system inner membrane component
MIDIMPMF_01650 1.4e-170 P Binding-protein-dependent transport system inner membrane component
MIDIMPMF_01651 4.6e-310 E ABC transporter, substrate-binding protein, family 5
MIDIMPMF_01652 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIDIMPMF_01653 2.2e-276 G Bacterial extracellular solute-binding protein
MIDIMPMF_01654 7.9e-64 G carbohydrate transport
MIDIMPMF_01655 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MIDIMPMF_01656 5.5e-124 G ABC transporter permease
MIDIMPMF_01657 2.9e-190 K Periplasmic binding protein domain
MIDIMPMF_01658 6.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MIDIMPMF_01659 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
MIDIMPMF_01661 3.2e-41 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MIDIMPMF_01662 7.5e-178 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MIDIMPMF_01663 4.5e-110 cas4 3.1.12.1 L Domain of unknown function DUF83
MIDIMPMF_01664 1.3e-149 cas7c L CRISPR-associated protein Cas7
MIDIMPMF_01665 7.2e-245 csd1 S CRISPR-associated protein (Cas_Csd1)
MIDIMPMF_01666 1.6e-101 cas5d S CRISPR-associated protein (Cas_Cas5)
MIDIMPMF_01667 2.5e-309 L DEAD-like helicases superfamily
MIDIMPMF_01668 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIDIMPMF_01669 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MIDIMPMF_01670 2.2e-276 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
MIDIMPMF_01671 3.5e-126 XK27_08050 O prohibitin homologues
MIDIMPMF_01672 4.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
MIDIMPMF_01673 5.7e-233 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MIDIMPMF_01674 6.2e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
MIDIMPMF_01675 1.8e-212 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MIDIMPMF_01676 0.0 macB_2 V ATPases associated with a variety of cellular activities
MIDIMPMF_01677 0.0 ctpE P E1-E2 ATPase
MIDIMPMF_01678 2.3e-33 K acetyltransferase
MIDIMPMF_01679 3.2e-53 racA K MerR, DNA binding
MIDIMPMF_01680 1e-195 yghZ C Aldo/keto reductase family
MIDIMPMF_01681 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MIDIMPMF_01682 9.2e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
MIDIMPMF_01683 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
MIDIMPMF_01684 1.5e-121 S Short repeat of unknown function (DUF308)
MIDIMPMF_01685 0.0 pepO 3.4.24.71 O Peptidase family M13
MIDIMPMF_01686 2.2e-104 L Single-strand binding protein family
MIDIMPMF_01687 3.2e-170
MIDIMPMF_01688 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MIDIMPMF_01691 3e-270 recD2 3.6.4.12 L PIF1-like helicase
MIDIMPMF_01692 4e-161 supH S Sucrose-6F-phosphate phosphohydrolase
MIDIMPMF_01693 4.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIDIMPMF_01694 6.5e-82 T PhoQ Sensor
MIDIMPMF_01695 5e-24 KT Transcriptional regulatory protein, C terminal
MIDIMPMF_01696 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MIDIMPMF_01697 1.3e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MIDIMPMF_01698 2.3e-191 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
MIDIMPMF_01699 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
MIDIMPMF_01700 1e-49 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MIDIMPMF_01701 5.5e-186 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MIDIMPMF_01702 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIDIMPMF_01703 3.9e-36 rpmE J Binds the 23S rRNA
MIDIMPMF_01705 6.2e-196 K helix_turn_helix, arabinose operon control protein
MIDIMPMF_01706 2.6e-163 glcU G Sugar transport protein
MIDIMPMF_01707 1.2e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MIDIMPMF_01708 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
MIDIMPMF_01709 1.5e-108
MIDIMPMF_01710 4.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MIDIMPMF_01711 1.4e-140 3.5.2.6 V Beta-lactamase enzyme family
MIDIMPMF_01712 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
MIDIMPMF_01713 4.2e-164 EG EamA-like transporter family
MIDIMPMF_01715 7.2e-123 V FtsX-like permease family
MIDIMPMF_01716 5e-146 S Sulfite exporter TauE/SafE
MIDIMPMF_01718 1.6e-28 L Transposase
MIDIMPMF_01719 3.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
MIDIMPMF_01720 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
MIDIMPMF_01721 7.9e-35 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
MIDIMPMF_01722 5.9e-77 EGP Major facilitator superfamily
MIDIMPMF_01723 1.1e-10 K Winged helix DNA-binding domain
MIDIMPMF_01724 6.3e-179 glkA 2.7.1.2 G ROK family
MIDIMPMF_01725 8e-296 S ATPases associated with a variety of cellular activities
MIDIMPMF_01726 8.5e-57 EGP Major facilitator Superfamily
MIDIMPMF_01727 9.9e-160 I alpha/beta hydrolase fold
MIDIMPMF_01728 2.3e-113 S Pyridoxamine 5'-phosphate oxidase
MIDIMPMF_01730 7.5e-49 S DUF218 domain
MIDIMPMF_01731 9.6e-40 S Protein of unknown function (DUF979)
MIDIMPMF_01732 1.7e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIDIMPMF_01734 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
MIDIMPMF_01735 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
MIDIMPMF_01736 7.1e-172 tesB I Thioesterase-like superfamily
MIDIMPMF_01737 1.3e-77 S Protein of unknown function (DUF3180)
MIDIMPMF_01738 2.7e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIDIMPMF_01739 8.9e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MIDIMPMF_01740 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
MIDIMPMF_01741 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIDIMPMF_01742 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MIDIMPMF_01743 3.9e-212 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MIDIMPMF_01744 1.6e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
MIDIMPMF_01745 3.6e-307
MIDIMPMF_01746 1.7e-168 natA V ATPases associated with a variety of cellular activities
MIDIMPMF_01747 1.3e-232 epsG M Glycosyl transferase family 21
MIDIMPMF_01748 5.7e-273 S AI-2E family transporter
MIDIMPMF_01749 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
MIDIMPMF_01750 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MIDIMPMF_01753 4.8e-67 S Domain of unknown function (DUF4190)
MIDIMPMF_01754 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MIDIMPMF_01755 1.6e-154 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MIDIMPMF_01757 1.6e-17 S Transcription factor WhiB
MIDIMPMF_01758 5e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
MIDIMPMF_01759 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MIDIMPMF_01760 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
MIDIMPMF_01761 7.5e-183 lacR K Transcriptional regulator, LacI family
MIDIMPMF_01762 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MIDIMPMF_01763 3.9e-119 K Transcriptional regulatory protein, C terminal
MIDIMPMF_01764 2.2e-95
MIDIMPMF_01765 1.9e-179 V N-Acetylmuramoyl-L-alanine amidase
MIDIMPMF_01766 2.6e-106 ytrE V ABC transporter
MIDIMPMF_01767 8.6e-172
MIDIMPMF_01768 6.7e-07 S Psort location CytoplasmicMembrane, score 9.99
MIDIMPMF_01769 4.7e-220 vex3 V ABC transporter permease
MIDIMPMF_01770 7.2e-212 vex1 V Efflux ABC transporter, permease protein
MIDIMPMF_01771 9.9e-112 vex2 V ABC transporter, ATP-binding protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)