ORF_ID e_value Gene_name EC_number CAZy COGs Description
FLDMCAKM_00003 2.7e-14
FLDMCAKM_00004 2.2e-14 L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FLDMCAKM_00005 5.6e-45
FLDMCAKM_00006 4.7e-34
FLDMCAKM_00008 5.9e-99 3.6.4.12 L DnaB-like helicase C terminal domain
FLDMCAKM_00011 9.2e-120 recD 3.1.11.5 L Helix-hairpin-helix containing domain
FLDMCAKM_00013 4.7e-74 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
FLDMCAKM_00014 2.3e-51 pnuC H Nicotinamide mononucleotide transporter
FLDMCAKM_00017 3.9e-11
FLDMCAKM_00030 5.5e-94 L transposase, IS605 OrfB family
FLDMCAKM_00031 4.1e-29 S RNA ligase
FLDMCAKM_00032 2.1e-95 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
FLDMCAKM_00041 1.1e-61 2.7.1.74, 2.7.1.76 F Nucleoside
FLDMCAKM_00044 2.9e-106 S Adenine-specific methyltransferase EcoRI
FLDMCAKM_00045 1.3e-141 L Psort location Cytoplasmic, score
FLDMCAKM_00046 6.3e-87 L Integrase
FLDMCAKM_00047 1.3e-31 lytE M LysM domain protein
FLDMCAKM_00048 2.5e-59 tdk 2.7.1.21 F Thymidine kinase
FLDMCAKM_00051 7.8e-36 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
FLDMCAKM_00057 1.9e-30 S Protein of unknown function (DUF1064)
FLDMCAKM_00058 1.4e-67 S DNA ligase (ATP) activity
FLDMCAKM_00060 8.7e-228 dnaE_2 2.7.7.7 L DNA polymerase
FLDMCAKM_00061 2.4e-47 S PD-(D/E)XK nuclease superfamily
FLDMCAKM_00062 1.2e-37 S DNA primase activity
FLDMCAKM_00063 6.9e-138 L Probable transposase
FLDMCAKM_00064 2.4e-94 S Glycosyl hydrolases family 25
FLDMCAKM_00065 1.8e-14 M Glycosyl hydrolases family 25
FLDMCAKM_00066 1.5e-09
FLDMCAKM_00069 2.2e-09
FLDMCAKM_00070 8.3e-107 fliC N bacterial-type flagellum-dependent cell motility
FLDMCAKM_00071 7.1e-67
FLDMCAKM_00072 1.7e-54
FLDMCAKM_00073 1.6e-63 D Phage-related minor tail protein
FLDMCAKM_00074 1.2e-79 xerH L Belongs to the 'phage' integrase family
FLDMCAKM_00077 2e-171 tnpB L Putative transposase DNA-binding domain
FLDMCAKM_00078 3.3e-89 L Resolvase, N-terminal
FLDMCAKM_00079 6.5e-09 hol S COG5546 Small integral membrane protein
FLDMCAKM_00081 1.6e-08
FLDMCAKM_00083 1.4e-18
FLDMCAKM_00084 9.2e-51 spoIVFA GT2,GT4 D peptidase
FLDMCAKM_00085 1.4e-33
FLDMCAKM_00091 1.4e-67
FLDMCAKM_00093 9.2e-53
FLDMCAKM_00094 8.3e-35
FLDMCAKM_00095 4.7e-172 gp17a S Terminase-like family
FLDMCAKM_00096 1.2e-18
FLDMCAKM_00098 1.9e-08 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FLDMCAKM_00100 2.6e-14 S Replication initiator protein A (RepA) N-terminus
FLDMCAKM_00101 1.5e-83 D CobQ CobB MinD ParA nucleotide binding domain protein
FLDMCAKM_00103 4.7e-38
FLDMCAKM_00105 4.3e-32 D Alpha beta
FLDMCAKM_00106 4.8e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDMCAKM_00107 1.5e-217 patA 2.6.1.1 E Aminotransferase
FLDMCAKM_00108 1e-34
FLDMCAKM_00109 0.0 clpL O associated with various cellular activities
FLDMCAKM_00110 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLDMCAKM_00111 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
FLDMCAKM_00112 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
FLDMCAKM_00113 7.5e-163 yvgN C Aldo keto reductase
FLDMCAKM_00114 3.1e-287 glpQ 3.1.4.46 C phosphodiesterase
FLDMCAKM_00115 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
FLDMCAKM_00116 1.1e-111 ybhR V ABC transporter
FLDMCAKM_00117 1.4e-36 ybhR V ABC transporter
FLDMCAKM_00118 8.4e-20 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
FLDMCAKM_00119 1.8e-78 K transcriptional regulator
FLDMCAKM_00120 1.6e-166 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FLDMCAKM_00121 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FLDMCAKM_00122 3.9e-254 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
FLDMCAKM_00123 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FLDMCAKM_00124 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FLDMCAKM_00125 7.2e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FLDMCAKM_00126 1.2e-31 gntT EG gluconate transmembrane transporter activity
FLDMCAKM_00127 6.1e-28 gntT EG gluconate transmembrane transporter activity
FLDMCAKM_00128 4.7e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FLDMCAKM_00129 9e-47
FLDMCAKM_00130 2.1e-272 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
FLDMCAKM_00131 1.6e-258 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
FLDMCAKM_00132 1.5e-147 metQ1 P Belongs to the nlpA lipoprotein family
FLDMCAKM_00133 4.4e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLDMCAKM_00134 7.6e-97 metI P ABC transporter permease
FLDMCAKM_00135 4.9e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
FLDMCAKM_00136 3.1e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLDMCAKM_00137 3.7e-196 brnQ U Component of the transport system for branched-chain amino acids
FLDMCAKM_00138 1.4e-122 iolS C Aldo keto reductase
FLDMCAKM_00139 9.9e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FLDMCAKM_00140 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDMCAKM_00141 1e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
FLDMCAKM_00142 2.9e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDMCAKM_00144 1.3e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
FLDMCAKM_00145 0.0 sbcC L Putative exonuclease SbcCD, C subunit
FLDMCAKM_00146 1.6e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FLDMCAKM_00148 9.6e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
FLDMCAKM_00149 3.6e-86 L hmm pf00665
FLDMCAKM_00150 4.1e-50 L Helix-turn-helix domain
FLDMCAKM_00151 2e-219 iscS 2.8.1.7 E Aminotransferase class V
FLDMCAKM_00163 1.4e-210 G Major Facilitator Superfamily
FLDMCAKM_00164 7.2e-175 citR K sugar-binding domain protein
FLDMCAKM_00165 1.7e-149 glcU U sugar transport
FLDMCAKM_00166 8e-25
FLDMCAKM_00167 0.0 mco Q Multicopper oxidase
FLDMCAKM_00168 2e-152 L Integrase core domain
FLDMCAKM_00169 1e-35 L Transposase and inactivated derivatives
FLDMCAKM_00170 4.6e-37 M LysM domain
FLDMCAKM_00171 4e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
FLDMCAKM_00172 7.4e-207 EG GntP family permease
FLDMCAKM_00173 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLDMCAKM_00174 3.3e-214 iscS2 2.8.1.7 E Aminotransferase class V
FLDMCAKM_00175 3.7e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FLDMCAKM_00176 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FLDMCAKM_00179 5.5e-26 S YjcQ protein
FLDMCAKM_00180 2.3e-148 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLDMCAKM_00181 3.8e-131 S Membrane
FLDMCAKM_00182 1.3e-75 4.4.1.5 E Glyoxalase
FLDMCAKM_00183 1.7e-84 yueI S Protein of unknown function (DUF1694)
FLDMCAKM_00184 3.8e-235 rarA L recombination factor protein RarA
FLDMCAKM_00186 4e-81 usp6 T universal stress protein
FLDMCAKM_00187 5.4e-150 2.3.1.19 K Helix-turn-helix XRE-family like proteins
FLDMCAKM_00188 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
FLDMCAKM_00189 4e-181 S Protein of unknown function (DUF2785)
FLDMCAKM_00191 2.2e-221 rodA D Belongs to the SEDS family
FLDMCAKM_00192 7.9e-32 S Protein of unknown function (DUF2969)
FLDMCAKM_00193 1e-182 mbl D Cell shape determining protein MreB Mrl
FLDMCAKM_00194 2.7e-219 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FLDMCAKM_00195 2.8e-29 S Protein of unknown function (DUF1146)
FLDMCAKM_00196 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
FLDMCAKM_00197 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FLDMCAKM_00198 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FLDMCAKM_00199 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FLDMCAKM_00200 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLDMCAKM_00201 1.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FLDMCAKM_00202 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLDMCAKM_00203 1.3e-128 atpB C it plays a direct role in the translocation of protons across the membrane
FLDMCAKM_00204 7.7e-217 pyrP F Permease
FLDMCAKM_00205 8e-124 yibF S overlaps another CDS with the same product name
FLDMCAKM_00206 9e-185 yibE S overlaps another CDS with the same product name
FLDMCAKM_00207 3.6e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FLDMCAKM_00208 8.6e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FLDMCAKM_00209 1.4e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FLDMCAKM_00210 3.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FLDMCAKM_00211 5.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FLDMCAKM_00212 3.2e-109 tdk 2.7.1.21 F thymidine kinase
FLDMCAKM_00213 3.2e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
FLDMCAKM_00214 7.5e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
FLDMCAKM_00215 2.8e-48
FLDMCAKM_00216 1.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLDMCAKM_00217 6.3e-193 ampC V Beta-lactamase
FLDMCAKM_00218 6.9e-106 yfiC V ABC transporter
FLDMCAKM_00219 6.2e-121 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
FLDMCAKM_00222 9.7e-31 T His Kinase A (phosphoacceptor) domain
FLDMCAKM_00223 1.2e-12 T PhoQ Sensor
FLDMCAKM_00224 3.8e-126 P CorA-like Mg2+ transporter protein
FLDMCAKM_00235 3.3e-67 L Putative transposase of IS4/5 family (DUF4096)
FLDMCAKM_00236 1e-75 L Transposase DDE domain
FLDMCAKM_00237 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FLDMCAKM_00238 5.5e-61 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FLDMCAKM_00239 1.2e-37 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
FLDMCAKM_00240 1.9e-60 G Transporter, major facilitator family protein
FLDMCAKM_00241 5.5e-208 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
FLDMCAKM_00242 1.8e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FLDMCAKM_00243 1.4e-167 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FLDMCAKM_00244 2.5e-40 gcvR T Belongs to the UPF0237 family
FLDMCAKM_00245 6e-244 XK27_08635 S UPF0210 protein
FLDMCAKM_00246 1.1e-178 yobV1 K WYL domain
FLDMCAKM_00247 9.9e-56 S pyridoxamine 5-phosphate
FLDMCAKM_00248 8.2e-34
FLDMCAKM_00250 1.3e-63
FLDMCAKM_00251 1.4e-111 yicL EG EamA-like transporter family
FLDMCAKM_00252 1.3e-70 S Domain of unknown function (DUF4352)
FLDMCAKM_00253 1.1e-283 1.3.5.4 C FAD binding domain
FLDMCAKM_00254 1.4e-41 1.3.5.4 C FAD binding domain
FLDMCAKM_00255 1.6e-163 K LysR substrate binding domain
FLDMCAKM_00256 7.7e-160 rssA S Phospholipase, patatin family
FLDMCAKM_00257 4.8e-213 phbA 2.3.1.9 I Belongs to the thiolase family
FLDMCAKM_00258 3.1e-177 S AI-2E family transporter
FLDMCAKM_00259 2.9e-18 S membrane transporter protein
FLDMCAKM_00260 3e-35 S membrane transporter protein
FLDMCAKM_00261 3.2e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
FLDMCAKM_00262 3.8e-193 V Beta-lactamase
FLDMCAKM_00263 9.2e-228
FLDMCAKM_00265 5.3e-153 S Alpha/beta hydrolase of unknown function (DUF915)
FLDMCAKM_00266 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLDMCAKM_00267 3.5e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
FLDMCAKM_00268 1.7e-162 endA F DNA RNA non-specific endonuclease
FLDMCAKM_00269 1.4e-267 pipD E Dipeptidase
FLDMCAKM_00271 1.2e-252 yifK E Amino acid permease
FLDMCAKM_00273 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FLDMCAKM_00274 2.3e-234 N Uncharacterized conserved protein (DUF2075)
FLDMCAKM_00275 4.1e-55 S SNARE associated Golgi protein
FLDMCAKM_00276 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
FLDMCAKM_00277 1.6e-97 padR K Virulence activator alpha C-term
FLDMCAKM_00278 4.7e-94 padC Q Phenolic acid decarboxylase
FLDMCAKM_00280 4.7e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
FLDMCAKM_00282 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
FLDMCAKM_00283 1.2e-24 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
FLDMCAKM_00284 6.4e-93 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FLDMCAKM_00285 5.6e-13 mleR K LysR family
FLDMCAKM_00286 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
FLDMCAKM_00287 1.2e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLDMCAKM_00288 1.7e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FLDMCAKM_00289 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLDMCAKM_00290 1.6e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
FLDMCAKM_00291 2.2e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FLDMCAKM_00292 8.7e-87 yabR J RNA binding
FLDMCAKM_00293 1.5e-56 divIC D Septum formation initiator
FLDMCAKM_00294 1.6e-39 yabO J S4 domain protein
FLDMCAKM_00295 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLDMCAKM_00296 2.4e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FLDMCAKM_00297 8.1e-114 S (CBS) domain
FLDMCAKM_00298 1.9e-56 L Toxic component of a toxin-antitoxin (TA) module
FLDMCAKM_00299 7.6e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLDMCAKM_00300 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FLDMCAKM_00301 1.9e-251 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FLDMCAKM_00302 2.1e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FLDMCAKM_00303 2.9e-157 htpX O Belongs to the peptidase M48B family
FLDMCAKM_00304 6.9e-85 lemA S LemA family
FLDMCAKM_00305 1.8e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLDMCAKM_00306 4.7e-123 srtA 3.4.22.70 M sortase family
FLDMCAKM_00307 8.6e-18 mdtG EGP Major facilitator Superfamily
FLDMCAKM_00308 3.3e-29 mdtG EGP Major facilitator Superfamily
FLDMCAKM_00309 6e-41 rpmE2 J Ribosomal protein L31
FLDMCAKM_00310 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLDMCAKM_00311 4.4e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FLDMCAKM_00312 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FLDMCAKM_00313 3.2e-74 ywiB S Domain of unknown function (DUF1934)
FLDMCAKM_00314 4.3e-266 ywfO S HD domain protein
FLDMCAKM_00315 1.2e-141 yxeH S hydrolase
FLDMCAKM_00316 1.5e-31
FLDMCAKM_00317 1.4e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLDMCAKM_00318 4e-203 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLDMCAKM_00319 2.2e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
FLDMCAKM_00320 9.4e-128 znuB U ABC 3 transport family
FLDMCAKM_00321 3.5e-94 fhuC P ABC transporter
FLDMCAKM_00322 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
FLDMCAKM_00323 1.4e-158 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FLDMCAKM_00324 6.1e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FLDMCAKM_00325 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FLDMCAKM_00326 7.6e-146 tatD L hydrolase, TatD family
FLDMCAKM_00327 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLDMCAKM_00328 4.9e-159 yunF F Protein of unknown function DUF72
FLDMCAKM_00329 2.9e-210 norA EGP Major facilitator Superfamily
FLDMCAKM_00330 1.3e-19 L transposase, IS605 OrfB family
FLDMCAKM_00336 4.4e-55 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FLDMCAKM_00337 1.2e-26 L Transposase
FLDMCAKM_00338 6.8e-52 L transposase, IS605 OrfB family
FLDMCAKM_00339 1e-233 lmrB EGP Major facilitator Superfamily
FLDMCAKM_00341 0.0 S Bacterial membrane protein YfhO
FLDMCAKM_00342 5.7e-48
FLDMCAKM_00343 0.0 kup P Transport of potassium into the cell
FLDMCAKM_00345 2e-283 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLDMCAKM_00346 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
FLDMCAKM_00347 0.0 yjbQ P TrkA C-terminal domain protein
FLDMCAKM_00348 4.8e-276 pipD E Dipeptidase
FLDMCAKM_00349 2.5e-153 S Alpha/beta hydrolase of unknown function (DUF915)
FLDMCAKM_00350 1.3e-235 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FLDMCAKM_00351 1.6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLDMCAKM_00352 4.5e-168 T Calcineurin-like phosphoesterase superfamily domain
FLDMCAKM_00353 4.3e-160 EGP Major facilitator Superfamily
FLDMCAKM_00354 1.1e-199 mdtG EGP Major facilitator Superfamily
FLDMCAKM_00355 7.6e-250 yhdP S Transporter associated domain
FLDMCAKM_00356 1.4e-210 naiP EGP Major facilitator Superfamily
FLDMCAKM_00357 4.1e-61 K LysR substrate binding domain protein
FLDMCAKM_00358 3.4e-16 K LysR substrate binding domain protein
FLDMCAKM_00359 4.9e-215 E GDSL-like Lipase/Acylhydrolase family
FLDMCAKM_00360 1.9e-194 lplA 6.3.1.20 H Lipoate-protein ligase
FLDMCAKM_00361 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
FLDMCAKM_00362 2.5e-199 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FLDMCAKM_00363 1.7e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
FLDMCAKM_00364 1.8e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
FLDMCAKM_00365 3.1e-14 yphJ 4.1.1.44 S decarboxylase
FLDMCAKM_00366 4.2e-25 yphJ 4.1.1.44 S decarboxylase
FLDMCAKM_00367 9.1e-53 azlD E Branched-chain amino acid transport
FLDMCAKM_00368 3.2e-75 azlC E azaleucine resistance protein AzlC
FLDMCAKM_00369 7.6e-21 azlC E azaleucine resistance protein AzlC
FLDMCAKM_00370 1.3e-284 thrC 4.2.3.1 E Threonine synthase
FLDMCAKM_00371 9.5e-231 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
FLDMCAKM_00372 8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FLDMCAKM_00373 1e-98 K Acetyltransferase (GNAT) domain
FLDMCAKM_00374 2e-112 ylbE GM NAD(P)H-binding
FLDMCAKM_00375 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
FLDMCAKM_00376 1.3e-131 S Belongs to the UPF0246 family
FLDMCAKM_00377 4.6e-98
FLDMCAKM_00378 5.5e-161 degV S EDD domain protein, DegV family
FLDMCAKM_00379 0.0 FbpA K Fibronectin-binding protein
FLDMCAKM_00380 1.4e-103 pncA Q Isochorismatase family
FLDMCAKM_00381 3.2e-150 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FLDMCAKM_00382 2.4e-77 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FLDMCAKM_00383 4.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
FLDMCAKM_00384 9.9e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FLDMCAKM_00385 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FLDMCAKM_00386 3.8e-189 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FLDMCAKM_00387 0.0 smc D Required for chromosome condensation and partitioning
FLDMCAKM_00388 5.2e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FLDMCAKM_00389 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLDMCAKM_00390 5.3e-163 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FLDMCAKM_00391 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLDMCAKM_00392 3.6e-302 yloV S DAK2 domain fusion protein YloV
FLDMCAKM_00393 3.6e-58 asp S Asp23 family, cell envelope-related function
FLDMCAKM_00394 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
FLDMCAKM_00395 7.5e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
FLDMCAKM_00396 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
FLDMCAKM_00397 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FLDMCAKM_00398 0.0 KLT serine threonine protein kinase
FLDMCAKM_00399 4.2e-130 stp 3.1.3.16 T phosphatase
FLDMCAKM_00400 5.5e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FLDMCAKM_00401 2.3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FLDMCAKM_00402 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLDMCAKM_00403 1.5e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLDMCAKM_00404 2.7e-45 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FLDMCAKM_00405 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
FLDMCAKM_00406 3.3e-15
FLDMCAKM_00407 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
FLDMCAKM_00408 6.2e-76 argR K Regulates arginine biosynthesis genes
FLDMCAKM_00409 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
FLDMCAKM_00410 1.4e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FLDMCAKM_00411 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FLDMCAKM_00412 2.5e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FLDMCAKM_00413 2.9e-159 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FLDMCAKM_00414 5.8e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLDMCAKM_00415 4.1e-72 yqhY S Asp23 family, cell envelope-related function
FLDMCAKM_00416 4.4e-205 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FLDMCAKM_00417 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
FLDMCAKM_00418 9e-53 ysxB J Cysteine protease Prp
FLDMCAKM_00419 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
FLDMCAKM_00420 4.8e-114 K Transcriptional regulator
FLDMCAKM_00422 3.9e-120 kdsD 2.5.1.55, 5.3.1.13 M sugar phosphate isomerase involved in capsule formation
FLDMCAKM_00423 8.3e-114 kdsA 2.5.1.55 H Belongs to the KdsA family
FLDMCAKM_00424 7.9e-70 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
FLDMCAKM_00425 2.4e-107 ygfC K Bacterial regulatory proteins, tetR family
FLDMCAKM_00426 4.7e-156 hrtB V ABC transporter permease
FLDMCAKM_00427 3.9e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
FLDMCAKM_00428 1.2e-74 argR K Regulates arginine biosynthesis genes
FLDMCAKM_00429 8.4e-45 czrA K Transcriptional regulator, ArsR family
FLDMCAKM_00430 1.5e-172 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FLDMCAKM_00431 1.3e-82 scrR K Transcriptional regulator, LacI family
FLDMCAKM_00432 8.3e-76 scrR K Transcriptional regulator, LacI family
FLDMCAKM_00433 9.5e-26
FLDMCAKM_00434 4.9e-103
FLDMCAKM_00435 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FLDMCAKM_00436 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
FLDMCAKM_00437 1.5e-55
FLDMCAKM_00438 7e-124 yrkL S Flavodoxin-like fold
FLDMCAKM_00440 4.4e-64 yeaO S Protein of unknown function, DUF488
FLDMCAKM_00441 5e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
FLDMCAKM_00442 4.2e-206 3.1.3.1 S associated with various cellular activities
FLDMCAKM_00443 9.9e-214 S Putative metallopeptidase domain
FLDMCAKM_00444 4.7e-45
FLDMCAKM_00445 4.5e-228 pbuG S permease
FLDMCAKM_00446 0.0 pepO 3.4.24.71 O Peptidase family M13
FLDMCAKM_00447 7.7e-91 ymdB S Macro domain protein
FLDMCAKM_00448 3.4e-146 pnuC H nicotinamide mononucleotide transporter
FLDMCAKM_00449 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FLDMCAKM_00450 2.6e-169 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDMCAKM_00451 2e-52
FLDMCAKM_00452 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
FLDMCAKM_00453 6.3e-120 tcyB U Binding-protein-dependent transport system inner membrane component
FLDMCAKM_00454 8.7e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FLDMCAKM_00455 6.9e-36
FLDMCAKM_00456 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
FLDMCAKM_00457 1.3e-142 ptp3 3.1.3.48 T Tyrosine phosphatase family
FLDMCAKM_00458 1.1e-180 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
FLDMCAKM_00459 1.8e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FLDMCAKM_00460 8.4e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
FLDMCAKM_00461 5.1e-179 galR K Transcriptional regulator
FLDMCAKM_00462 0.0 rafA 3.2.1.22 G alpha-galactosidase
FLDMCAKM_00463 1.6e-274 lacS G Transporter
FLDMCAKM_00464 2e-123 S Membrane
FLDMCAKM_00465 1.2e-233 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FLDMCAKM_00466 0.0 pepF E oligoendopeptidase F
FLDMCAKM_00467 2.6e-175 K helix_turn _helix lactose operon repressor
FLDMCAKM_00468 2.3e-72 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDMCAKM_00469 4e-50 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDMCAKM_00470 8.1e-76 K AsnC family
FLDMCAKM_00471 3.5e-271 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
FLDMCAKM_00472 1.2e-154 yitU 3.1.3.104 S hydrolase
FLDMCAKM_00473 4.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FLDMCAKM_00474 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
FLDMCAKM_00475 3.1e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FLDMCAKM_00476 1.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FLDMCAKM_00477 8e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FLDMCAKM_00478 4.5e-114 ycsI S Protein of unknown function (DUF1445)
FLDMCAKM_00480 5.5e-38 L transposase and inactivated derivatives, IS30 family
FLDMCAKM_00481 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
FLDMCAKM_00483 3.9e-204 3.5.1.104 M hydrolase, family 25
FLDMCAKM_00484 1.7e-30 S Bacteriophage holin of superfamily 6 (Holin_LLH)
FLDMCAKM_00486 8.4e-34
FLDMCAKM_00489 3.3e-67 S Domain of unknown function (DUF2479)
FLDMCAKM_00491 3.9e-73
FLDMCAKM_00492 1.7e-75 spr M Prophage endopeptidase tail
FLDMCAKM_00493 1.2e-80 S Phage tail protein
FLDMCAKM_00494 0.0 M Phage tail tape measure protein TP901
FLDMCAKM_00495 1.2e-49 S Phage tail assembly chaperone proteins, TAC
FLDMCAKM_00496 5.6e-96 S Phage tail tube protein
FLDMCAKM_00497 6.3e-18 S Protein of unknown function (DUF806)
FLDMCAKM_00498 1e-30 S Bacteriophage HK97-gp10, putative tail-component
FLDMCAKM_00499 6.5e-15 S Phage head-tail joining protein
FLDMCAKM_00500 2.6e-46
FLDMCAKM_00501 3.5e-167 G Phage capsid family
FLDMCAKM_00502 1.8e-184 S Phage portal protein
FLDMCAKM_00504 0.0 S Phage Terminase
FLDMCAKM_00505 6.6e-69 L Phage terminase, small subunit
FLDMCAKM_00506 7.8e-43
FLDMCAKM_00508 8.5e-21
FLDMCAKM_00514 8.8e-129
FLDMCAKM_00517 9.1e-32 L HNH nucleases
FLDMCAKM_00518 2.5e-40 L Phage terminase, small subunit
FLDMCAKM_00519 2.3e-267 S Phage Terminase
FLDMCAKM_00521 5.2e-144 S portal protein
FLDMCAKM_00522 5.3e-80 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
FLDMCAKM_00523 2.5e-121 S Phage capsid family
FLDMCAKM_00524 6.3e-29 S Phage gp6-like head-tail connector protein
FLDMCAKM_00525 5.7e-32 S Phage head-tail joining protein
FLDMCAKM_00526 2.3e-19
FLDMCAKM_00527 1.8e-23
FLDMCAKM_00528 1.1e-49 S Phage tail tube protein
FLDMCAKM_00529 4.8e-27
FLDMCAKM_00530 7e-185 M Phage tail tape measure protein TP901
FLDMCAKM_00531 1.5e-80 S Phage tail protein
FLDMCAKM_00532 5.9e-141 rny D peptidase
FLDMCAKM_00533 3.7e-51
FLDMCAKM_00536 1.3e-34 S GDSL-like Lipase/Acylhydrolase
FLDMCAKM_00537 2e-51
FLDMCAKM_00540 2.5e-24 S Bacteriophage holin of superfamily 6 (Holin_LLH)
FLDMCAKM_00541 4.8e-187 S peptidoglycan catabolic process
FLDMCAKM_00542 1.8e-27 gepA S Protein of unknown function (DUF4065)
FLDMCAKM_00543 5.4e-10
FLDMCAKM_00544 2.6e-249 V Type II restriction enzyme, methylase subunits
FLDMCAKM_00545 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
FLDMCAKM_00546 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
FLDMCAKM_00547 1.8e-195 6.3.1.20 H Lipoate-protein ligase
FLDMCAKM_00548 7.7e-172 lytH 3.5.1.28 M Ami_3
FLDMCAKM_00549 4.4e-168 yniA G Phosphotransferase enzyme family
FLDMCAKM_00550 1.5e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
FLDMCAKM_00551 2e-245 mmuP E amino acid
FLDMCAKM_00552 2.6e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
FLDMCAKM_00553 2.4e-212 hom1 1.1.1.3 E Homoserine dehydrogenase
FLDMCAKM_00554 1.5e-152 cjaA ET ABC transporter substrate-binding protein
FLDMCAKM_00555 1.1e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FLDMCAKM_00556 5.7e-94 P ABC transporter permease
FLDMCAKM_00557 1.7e-111 papP P ABC transporter, permease protein
FLDMCAKM_00559 2.7e-65 U ABC transporter, permease protein
FLDMCAKM_00560 9.9e-49 U Binding-protein-dependent transport system inner membrane component
FLDMCAKM_00561 6.4e-95 ET Bacterial periplasmic substrate-binding proteins
FLDMCAKM_00562 6.7e-86 3.6.3.21 E ABC transporter
FLDMCAKM_00563 1.2e-119 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
FLDMCAKM_00564 3.3e-133 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
FLDMCAKM_00565 3.7e-210 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
FLDMCAKM_00566 4.3e-217 metC1 2.5.1.48, 4.4.1.8 E cystathionine
FLDMCAKM_00567 9.7e-83 slyA K Transcriptional regulator
FLDMCAKM_00568 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FLDMCAKM_00569 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLDMCAKM_00570 1.7e-57
FLDMCAKM_00571 3.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
FLDMCAKM_00572 1.5e-180 prmA J Ribosomal protein L11 methyltransferase
FLDMCAKM_00573 1.2e-54
FLDMCAKM_00575 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FLDMCAKM_00576 2.6e-92 S integral membrane protein
FLDMCAKM_00577 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FLDMCAKM_00578 4e-139 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FLDMCAKM_00579 1.4e-142 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FLDMCAKM_00580 3.2e-17 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
FLDMCAKM_00581 1.1e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FLDMCAKM_00582 5.3e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FLDMCAKM_00583 3e-203 coiA 3.6.4.12 S Competence protein
FLDMCAKM_00584 1.8e-113 yjbH Q Thioredoxin
FLDMCAKM_00585 3e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
FLDMCAKM_00586 1.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLDMCAKM_00587 1.1e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
FLDMCAKM_00588 4.8e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
FLDMCAKM_00589 4.1e-161 rrmA 2.1.1.187 H Methyltransferase
FLDMCAKM_00590 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FLDMCAKM_00591 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
FLDMCAKM_00592 1.2e-07 S Protein of unknown function (DUF4044)
FLDMCAKM_00593 9.8e-58
FLDMCAKM_00594 5.6e-79 mraZ K Belongs to the MraZ family
FLDMCAKM_00595 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FLDMCAKM_00596 7e-09 ftsL D Cell division protein FtsL
FLDMCAKM_00597 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
FLDMCAKM_00598 1.3e-176 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLDMCAKM_00599 2.1e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLDMCAKM_00600 1e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLDMCAKM_00601 4.6e-149 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FLDMCAKM_00602 3.2e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FLDMCAKM_00603 9e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FLDMCAKM_00604 2.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FLDMCAKM_00605 6.8e-41 yggT S YGGT family
FLDMCAKM_00606 4.9e-145 ylmH S S4 domain protein
FLDMCAKM_00607 3.1e-111 divIVA D DivIVA domain protein
FLDMCAKM_00609 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FLDMCAKM_00610 6e-31 cspB K Cold shock protein
FLDMCAKM_00611 2.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
FLDMCAKM_00613 5.1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FLDMCAKM_00614 3.8e-57 XK27_04120 S Putative amino acid metabolism
FLDMCAKM_00615 5.8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FLDMCAKM_00616 1.9e-305 S amidohydrolase
FLDMCAKM_00617 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
FLDMCAKM_00618 4.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
FLDMCAKM_00619 1.6e-123 S Repeat protein
FLDMCAKM_00620 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FLDMCAKM_00621 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLDMCAKM_00622 2.7e-73 spx4 1.20.4.1 P ArsC family
FLDMCAKM_00623 6.4e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
FLDMCAKM_00624 2.2e-31 ykzG S Belongs to the UPF0356 family
FLDMCAKM_00625 1.2e-74
FLDMCAKM_00626 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FLDMCAKM_00627 2.4e-49 yktA S Belongs to the UPF0223 family
FLDMCAKM_00628 4.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
FLDMCAKM_00629 0.0 typA T GTP-binding protein TypA
FLDMCAKM_00630 7.1e-212 ftsW D Belongs to the SEDS family
FLDMCAKM_00631 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
FLDMCAKM_00632 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
FLDMCAKM_00633 1.1e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FLDMCAKM_00634 1.6e-196 ylbL T Belongs to the peptidase S16 family
FLDMCAKM_00635 6.5e-90 comEA L Competence protein ComEA
FLDMCAKM_00636 1.3e-87 comEB 3.5.4.12 F ComE operon protein 2
FLDMCAKM_00637 0.0 comEC S Competence protein ComEC
FLDMCAKM_00638 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
FLDMCAKM_00639 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
FLDMCAKM_00640 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FLDMCAKM_00641 7.4e-15 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
FLDMCAKM_00642 7.6e-141 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
FLDMCAKM_00643 1.1e-56 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
FLDMCAKM_00644 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLDMCAKM_00645 5e-162 S Tetratricopeptide repeat
FLDMCAKM_00646 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLDMCAKM_00647 2.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FLDMCAKM_00648 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLDMCAKM_00649 2.3e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
FLDMCAKM_00650 9.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
FLDMCAKM_00652 8.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FLDMCAKM_00653 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FLDMCAKM_00654 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FLDMCAKM_00655 2.7e-174 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FLDMCAKM_00656 4.3e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDMCAKM_00657 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
FLDMCAKM_00658 1.6e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLDMCAKM_00659 1.6e-61 S Domain of unknown function (DUF4440)
FLDMCAKM_00660 8.6e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDMCAKM_00661 9.6e-93 tesE Q hydratase
FLDMCAKM_00662 2.9e-43 adhR K helix_turn_helix, mercury resistance
FLDMCAKM_00663 4e-98 ywrO S Flavodoxin-like fold
FLDMCAKM_00664 2.5e-43 S Protein conserved in bacteria
FLDMCAKM_00665 3e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
FLDMCAKM_00666 2.8e-51 S Sugar efflux transporter for intercellular exchange
FLDMCAKM_00667 3.2e-15 xre K Helix-turn-helix domain
FLDMCAKM_00668 1.6e-199 gldA 1.1.1.6 C dehydrogenase
FLDMCAKM_00669 3.1e-218 L Probable transposase
FLDMCAKM_00670 3.6e-23 EGP Major Facilitator Superfamily
FLDMCAKM_00671 1.8e-10 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
FLDMCAKM_00672 7.4e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
FLDMCAKM_00673 4.2e-74 O OsmC-like protein
FLDMCAKM_00674 6.8e-75 K Transcriptional regulator
FLDMCAKM_00675 9.6e-161 proX M ABC transporter, substrate-binding protein, QAT family
FLDMCAKM_00676 2e-107 proWZ P ABC transporter permease
FLDMCAKM_00677 1.9e-141 proV E ABC transporter, ATP-binding protein
FLDMCAKM_00678 2.9e-100 proW P ABC transporter, permease protein
FLDMCAKM_00679 1.4e-130 C Zinc-binding dehydrogenase
FLDMCAKM_00680 7.6e-194 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
FLDMCAKM_00681 2.6e-32 4.4.1.8 E Aminotransferase, class I
FLDMCAKM_00682 2.8e-171 4.4.1.8 E Aminotransferase, class I
FLDMCAKM_00683 5.7e-177 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
FLDMCAKM_00684 1e-201 xerS L Belongs to the 'phage' integrase family
FLDMCAKM_00685 1.3e-18 ywkB S Membrane transport protein
FLDMCAKM_00686 1.8e-66 ywkB S Membrane transport protein
FLDMCAKM_00687 6.3e-39 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
FLDMCAKM_00688 8e-112 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
FLDMCAKM_00689 4.8e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
FLDMCAKM_00690 4.5e-80 hmpT S ECF-type riboflavin transporter, S component
FLDMCAKM_00692 4.4e-16 1.1.1.346 C Aldo keto reductase
FLDMCAKM_00693 2.3e-107 1.1.1.346 C Aldo keto reductase
FLDMCAKM_00694 4.9e-160 S DUF218 domain
FLDMCAKM_00697 1.4e-95 K Acetyltransferase (GNAT) domain
FLDMCAKM_00698 1.5e-52 I alpha/beta hydrolase fold
FLDMCAKM_00699 4.1e-24 I alpha/beta hydrolase fold
FLDMCAKM_00700 9e-116 S Phage minor capsid protein 2
FLDMCAKM_00703 1.7e-215 2.6.1.1 E Aminotransferase
FLDMCAKM_00704 3.6e-183 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
FLDMCAKM_00705 1.2e-135 EGP Sugar (and other) transporter
FLDMCAKM_00706 1.8e-51 EGP Sugar (and other) transporter
FLDMCAKM_00707 4.6e-97 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
FLDMCAKM_00708 1.2e-91 S Fic/DOC family
FLDMCAKM_00709 6.4e-70 yncA 2.3.1.79 S Maltose acetyltransferase
FLDMCAKM_00710 1.3e-103 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
FLDMCAKM_00711 1.3e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FLDMCAKM_00712 2.1e-261 arcD E Amino acid permease
FLDMCAKM_00713 5.8e-92 5.1.1.13 M racemase activity, acting on amino acids and derivatives
FLDMCAKM_00714 1.4e-51 clcA P chloride
FLDMCAKM_00715 2.9e-18 lmrB EGP Major facilitator Superfamily
FLDMCAKM_00717 2.4e-37 ykuJ S Protein of unknown function (DUF1797)
FLDMCAKM_00718 1.6e-180 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FLDMCAKM_00719 1.7e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
FLDMCAKM_00720 5.5e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
FLDMCAKM_00721 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLDMCAKM_00722 8.8e-38 ptsH G phosphocarrier protein HPR
FLDMCAKM_00724 0.0 clpE O Belongs to the ClpA ClpB family
FLDMCAKM_00725 2.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
FLDMCAKM_00726 1.1e-109 pncA Q Isochorismatase family
FLDMCAKM_00727 2.4e-259 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FLDMCAKM_00728 3.8e-97 S Pfam:DUF3816
FLDMCAKM_00729 4.3e-140 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
FLDMCAKM_00730 1.3e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLDMCAKM_00731 1.9e-161 EG EamA-like transporter family
FLDMCAKM_00732 2.7e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
FLDMCAKM_00733 2.3e-13
FLDMCAKM_00734 1.4e-153 V ABC transporter, ATP-binding protein
FLDMCAKM_00735 7.8e-64 gntR1 K Transcriptional regulator, GntR family
FLDMCAKM_00736 5.8e-169 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
FLDMCAKM_00737 7e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
FLDMCAKM_00738 1.3e-95 M transferase activity, transferring glycosyl groups
FLDMCAKM_00739 6.1e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FLDMCAKM_00740 1.9e-162 ykoT GT2 M Glycosyl transferase family 2
FLDMCAKM_00741 2.1e-141 yueF S AI-2E family transporter
FLDMCAKM_00742 1.3e-168 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
FLDMCAKM_00743 1.6e-09
FLDMCAKM_00744 5.9e-59 M repeat protein
FLDMCAKM_00745 1.2e-55 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FLDMCAKM_00746 9.1e-189 I Alpha beta
FLDMCAKM_00747 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
FLDMCAKM_00748 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FLDMCAKM_00750 7.2e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
FLDMCAKM_00751 1.9e-149 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
FLDMCAKM_00752 2.4e-114 S Domain of unknown function (DUF4811)
FLDMCAKM_00753 1.2e-266 lmrB EGP Major facilitator Superfamily
FLDMCAKM_00754 5.6e-74 merR K MerR HTH family regulatory protein
FLDMCAKM_00755 6e-55
FLDMCAKM_00756 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLDMCAKM_00757 1.3e-216 S CAAX protease self-immunity
FLDMCAKM_00758 8.1e-33 elaA S GNAT family
FLDMCAKM_00759 5e-84 usp1 T Belongs to the universal stress protein A family
FLDMCAKM_00760 5.4e-108 S VIT family
FLDMCAKM_00761 4.8e-112 S membrane
FLDMCAKM_00762 3.5e-163 czcD P cation diffusion facilitator family transporter
FLDMCAKM_00763 3.4e-123 sirR K iron dependent repressor
FLDMCAKM_00764 1.3e-30 cspA K Cold shock protein
FLDMCAKM_00765 6.3e-126 thrE S Putative threonine/serine exporter
FLDMCAKM_00766 3.7e-82 S Threonine/Serine exporter, ThrE
FLDMCAKM_00767 4.5e-115 lssY 3.6.1.27 I phosphatase
FLDMCAKM_00768 8.3e-156 I alpha/beta hydrolase fold
FLDMCAKM_00770 1.6e-266 lysP E amino acid
FLDMCAKM_00771 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
FLDMCAKM_00777 2e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDMCAKM_00778 2.2e-45 IQ reductase
FLDMCAKM_00779 3.2e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
FLDMCAKM_00780 9.3e-55 sdaAB 4.3.1.17 E Serine dehydratase beta chain
FLDMCAKM_00781 1.2e-94 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
FLDMCAKM_00782 4.1e-26 yitW S Iron-sulfur cluster assembly protein
FLDMCAKM_00783 1.6e-08 Q Signal peptide protein, YSIRK family
FLDMCAKM_00784 1.2e-65 UW LPXTG-motif cell wall anchor domain protein
FLDMCAKM_00785 1.5e-27 lutA C Cysteine-rich domain
FLDMCAKM_00786 3.5e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
FLDMCAKM_00787 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLDMCAKM_00788 2.4e-37 ynzC S UPF0291 protein
FLDMCAKM_00789 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
FLDMCAKM_00790 3.3e-115 plsC 2.3.1.51 I Acyltransferase
FLDMCAKM_00791 6.8e-136 yabB 2.1.1.223 L Methyltransferase small domain
FLDMCAKM_00792 2.3e-47 yazA L GIY-YIG catalytic domain protein
FLDMCAKM_00793 1.5e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
FLDMCAKM_00794 7.1e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FLDMCAKM_00795 4.5e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
FLDMCAKM_00796 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FLDMCAKM_00797 2.2e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLDMCAKM_00798 5.1e-134 cdsA 2.7.7.41 I Belongs to the CDS family
FLDMCAKM_00799 8e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
FLDMCAKM_00800 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FLDMCAKM_00801 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FLDMCAKM_00803 8.1e-211 E glutamate:sodium symporter activity
FLDMCAKM_00804 1.1e-14 3.2.1.17 NU mannosyl-glycoprotein
FLDMCAKM_00805 3.8e-93 wecD K Acetyltransferase (GNAT) family
FLDMCAKM_00806 4e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
FLDMCAKM_00807 2.9e-81 S Psort location Cytoplasmic, score
FLDMCAKM_00808 1.4e-69 K helix_turn_helix, mercury resistance
FLDMCAKM_00809 4.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
FLDMCAKM_00810 2.5e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
FLDMCAKM_00811 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FLDMCAKM_00812 7.6e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
FLDMCAKM_00813 4.4e-135 ycsF S LamB/YcsF family
FLDMCAKM_00814 5.7e-209 ycsG P Natural resistance-associated macrophage protein
FLDMCAKM_00815 1.4e-90 EGP Major facilitator Superfamily
FLDMCAKM_00816 9.3e-99 EGP Major facilitator Superfamily
FLDMCAKM_00817 2e-252 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
FLDMCAKM_00818 1.1e-52 trxA O Belongs to the thioredoxin family
FLDMCAKM_00819 3.5e-150 mleP3 S Membrane transport protein
FLDMCAKM_00821 4.1e-240 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLDMCAKM_00822 2.3e-241 yfnA E amino acid
FLDMCAKM_00823 6.1e-82 S NADPH-dependent FMN reductase
FLDMCAKM_00825 8.5e-156 L Thioesterase-like superfamily
FLDMCAKM_00826 6.4e-30 lacA S Hexapeptide repeat of succinyl-transferase
FLDMCAKM_00827 7.3e-261 argH 4.3.2.1 E argininosuccinate lyase
FLDMCAKM_00828 4e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
FLDMCAKM_00829 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FLDMCAKM_00830 3.1e-30 K Transcriptional regulator
FLDMCAKM_00831 1.5e-16 1.3.1.9 S Nitronate monooxygenase
FLDMCAKM_00832 2.3e-53 K Helix-turn-helix domain
FLDMCAKM_00833 1.2e-105 S Domain of unknown function (DUF4767)
FLDMCAKM_00834 2.6e-07
FLDMCAKM_00835 9.5e-97 G Belongs to the carbohydrate kinase PfkB family
FLDMCAKM_00836 4.5e-179 F Belongs to the purine-cytosine permease (2.A.39) family
FLDMCAKM_00837 2.1e-148 yegU O ADP-ribosylglycohydrolase
FLDMCAKM_00838 9.4e-172 L Transposase and inactivated derivatives IS30 family
FLDMCAKM_00839 3.2e-127 K Transcriptional regulatory protein, C-terminal domain protein
FLDMCAKM_00840 2.5e-158 pstS P Phosphate
FLDMCAKM_00841 1.2e-150 pstC P probably responsible for the translocation of the substrate across the membrane
FLDMCAKM_00842 9.4e-153 pstA P Phosphate transport system permease protein PstA
FLDMCAKM_00843 2.7e-12 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FLDMCAKM_00844 4.4e-106 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FLDMCAKM_00845 4e-122 phoU P Plays a role in the regulation of phosphate uptake
FLDMCAKM_00846 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
FLDMCAKM_00847 5.4e-40 ylqC S Belongs to the UPF0109 family
FLDMCAKM_00848 8e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FLDMCAKM_00849 3.2e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
FLDMCAKM_00850 4.9e-260 yfnA E Amino Acid
FLDMCAKM_00851 1.8e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FLDMCAKM_00852 3.8e-98 L Belongs to the 'phage' integrase family
FLDMCAKM_00853 4.7e-99 dam2 2.1.1.72 L DNA methyltransferase
FLDMCAKM_00854 6.2e-103 S AAA ATPase domain
FLDMCAKM_00855 3.1e-12
FLDMCAKM_00857 3.7e-22 E Zn peptidase
FLDMCAKM_00858 4.7e-35
FLDMCAKM_00859 2.5e-09
FLDMCAKM_00860 1.7e-17 3.4.21.88 K Helix-turn-helix domain
FLDMCAKM_00861 1.3e-09 K Helix-turn-helix XRE-family like proteins
FLDMCAKM_00862 9.8e-82 K Phage regulatory protein
FLDMCAKM_00864 5.1e-43
FLDMCAKM_00867 7.1e-149 recT L RecT family
FLDMCAKM_00868 5.8e-171 scrK 2.7.1.2, 2.7.1.4 GK ROK family
FLDMCAKM_00869 1e-232 mepA V MATE efflux family protein
FLDMCAKM_00870 9.7e-225 amtB P ammonium transporter
FLDMCAKM_00872 1.6e-132 XK27_08845 S ABC transporter, ATP-binding protein
FLDMCAKM_00873 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
FLDMCAKM_00874 1e-176 ABC-SBP S ABC transporter
FLDMCAKM_00875 2.1e-288 S ABC transporter, ATP-binding protein
FLDMCAKM_00876 3.4e-205 nrnB S DHHA1 domain
FLDMCAKM_00878 5.1e-110 M ErfK YbiS YcfS YnhG
FLDMCAKM_00879 1.4e-83 nrdI F NrdI Flavodoxin like
FLDMCAKM_00880 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLDMCAKM_00881 3.3e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
FLDMCAKM_00882 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
FLDMCAKM_00883 5.5e-274 S Uncharacterized protein conserved in bacteria (DUF2325)
FLDMCAKM_00884 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
FLDMCAKM_00885 3.1e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
FLDMCAKM_00886 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
FLDMCAKM_00887 6.1e-20 yjeM E Amino Acid
FLDMCAKM_00888 2.1e-07 yjeM E Amino Acid
FLDMCAKM_00889 2.6e-41 yjeM E Amino Acid
FLDMCAKM_00890 2.2e-168 ponA V Beta-lactamase enzyme family
FLDMCAKM_00891 9.3e-223 dacA 3.4.16.4 M Belongs to the peptidase S11 family
FLDMCAKM_00892 2e-97
FLDMCAKM_00893 5e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
FLDMCAKM_00894 8e-108 lssY 3.6.1.27 I Acid phosphatase homologues
FLDMCAKM_00895 1.6e-54 S MazG-like family
FLDMCAKM_00896 0.0 L Helicase C-terminal domain protein
FLDMCAKM_00897 4.7e-70 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
FLDMCAKM_00898 2.5e-95 K transcriptional regulator
FLDMCAKM_00899 4.8e-29 lmrB EGP Major facilitator Superfamily
FLDMCAKM_00900 3.6e-30 lmrB EGP Major facilitator Superfamily
FLDMCAKM_00901 2.5e-70 lmrB EGP Major facilitator Superfamily
FLDMCAKM_00902 1.9e-38 lmrB EGP Major facilitator Superfamily
FLDMCAKM_00905 1e-37 S Cytochrome B5
FLDMCAKM_00906 8.4e-182 hoxN U High-affinity nickel-transport protein
FLDMCAKM_00907 6.5e-148 larE S NAD synthase
FLDMCAKM_00908 3.2e-127 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
FLDMCAKM_00909 6.6e-214 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FLDMCAKM_00910 4.3e-130 cpmA S AIR carboxylase
FLDMCAKM_00911 1.8e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
FLDMCAKM_00912 5.9e-123 K Crp-like helix-turn-helix domain
FLDMCAKM_00913 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FLDMCAKM_00914 4.3e-109 ypsA S Belongs to the UPF0398 family
FLDMCAKM_00915 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FLDMCAKM_00916 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
FLDMCAKM_00917 1.2e-158 EG EamA-like transporter family
FLDMCAKM_00918 4e-192 C Aldo keto reductase family protein
FLDMCAKM_00919 1.3e-121 ypuA S Protein of unknown function (DUF1002)
FLDMCAKM_00920 4.7e-134 dnaD L DnaD domain protein
FLDMCAKM_00921 6e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
FLDMCAKM_00922 2.1e-88 ypmB S Protein conserved in bacteria
FLDMCAKM_00923 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
FLDMCAKM_00924 1.1e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
FLDMCAKM_00925 1.8e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
FLDMCAKM_00926 9.5e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
FLDMCAKM_00927 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FLDMCAKM_00928 5.2e-94 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FLDMCAKM_00929 1e-103 pstA P Phosphate transport system permease protein PstA
FLDMCAKM_00930 4.5e-97 pstC P probably responsible for the translocation of the substrate across the membrane
FLDMCAKM_00931 2e-91 pstS P Phosphate
FLDMCAKM_00932 3.2e-92 V ABC transporter
FLDMCAKM_00933 8.6e-56
FLDMCAKM_00934 1.2e-33 S Protein of unknown function (DUF2992)
FLDMCAKM_00935 1.6e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
FLDMCAKM_00936 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLDMCAKM_00937 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLDMCAKM_00938 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLDMCAKM_00939 4.1e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLDMCAKM_00940 4.7e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
FLDMCAKM_00941 1.1e-106 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLDMCAKM_00942 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
FLDMCAKM_00943 5.8e-241 purD 6.3.4.13 F Belongs to the GARS family
FLDMCAKM_00944 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FLDMCAKM_00945 5.7e-222 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
FLDMCAKM_00946 5.6e-178
FLDMCAKM_00947 1.1e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
FLDMCAKM_00948 6.2e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
FLDMCAKM_00949 0.0 copA 3.6.3.54 P P-type ATPase
FLDMCAKM_00950 1.1e-27 EGP Major facilitator Superfamily
FLDMCAKM_00951 2.3e-89 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
FLDMCAKM_00952 9.4e-158 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FLDMCAKM_00953 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
FLDMCAKM_00954 3e-110
FLDMCAKM_00955 4.9e-182 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
FLDMCAKM_00956 3.4e-118 S CAAX protease self-immunity
FLDMCAKM_00957 7.1e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLDMCAKM_00958 4.1e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
FLDMCAKM_00959 1.3e-102 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
FLDMCAKM_00960 8.9e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FLDMCAKM_00961 3.2e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
FLDMCAKM_00962 1e-199 folP 2.5.1.15 H dihydropteroate synthase
FLDMCAKM_00964 1.7e-36
FLDMCAKM_00966 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
FLDMCAKM_00967 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FLDMCAKM_00968 9.8e-56 yheA S Belongs to the UPF0342 family
FLDMCAKM_00969 9.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
FLDMCAKM_00970 2e-148 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FLDMCAKM_00972 1.4e-77 hit FG histidine triad
FLDMCAKM_00973 4e-133 ecsA V ABC transporter, ATP-binding protein
FLDMCAKM_00974 1e-210 ecsB U ABC transporter
FLDMCAKM_00975 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FLDMCAKM_00976 3.6e-57 ytzB S Small secreted protein
FLDMCAKM_00977 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FLDMCAKM_00978 7.8e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FLDMCAKM_00979 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
FLDMCAKM_00980 5.3e-114 ybhL S Belongs to the BI1 family
FLDMCAKM_00981 1.9e-138 aroD S Serine hydrolase (FSH1)
FLDMCAKM_00982 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLDMCAKM_00983 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FLDMCAKM_00984 1.8e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FLDMCAKM_00985 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FLDMCAKM_00986 1e-251 dnaB L replication initiation and membrane attachment
FLDMCAKM_00987 2.5e-172 dnaI L Primosomal protein DnaI
FLDMCAKM_00988 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FLDMCAKM_00989 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
FLDMCAKM_00990 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FLDMCAKM_00991 3.2e-19 yoaK S Protein of unknown function (DUF1275)
FLDMCAKM_00992 3.5e-25 yoaK S Protein of unknown function (DUF1275)
FLDMCAKM_00993 2.2e-96 yqeG S HAD phosphatase, family IIIA
FLDMCAKM_00994 7.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
FLDMCAKM_00995 2.6e-49 yhbY J RNA-binding protein
FLDMCAKM_00996 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FLDMCAKM_00997 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
FLDMCAKM_00998 6.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FLDMCAKM_00999 3e-136 yqeM Q Methyltransferase
FLDMCAKM_01000 6e-213 ylbM S Belongs to the UPF0348 family
FLDMCAKM_01001 3e-96 yceD S Uncharacterized ACR, COG1399
FLDMCAKM_01002 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
FLDMCAKM_01003 5.6e-121 K response regulator
FLDMCAKM_01004 1.5e-280 arlS 2.7.13.3 T Histidine kinase
FLDMCAKM_01005 1.4e-232 V MatE
FLDMCAKM_01006 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
FLDMCAKM_01007 6.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FLDMCAKM_01008 2.7e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
FLDMCAKM_01009 1.2e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLDMCAKM_01010 1.9e-89 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
FLDMCAKM_01011 7.8e-60 yodB K Transcriptional regulator, HxlR family
FLDMCAKM_01012 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FLDMCAKM_01013 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FLDMCAKM_01014 4e-116 udk 2.7.1.48 F Cytidine monophosphokinase
FLDMCAKM_01015 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FLDMCAKM_01016 0.0 S membrane
FLDMCAKM_01017 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
FLDMCAKM_01018 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FLDMCAKM_01019 2.4e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLDMCAKM_01020 1.1e-104 gluP 3.4.21.105 S Peptidase, S54 family
FLDMCAKM_01021 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
FLDMCAKM_01022 1.4e-178 glk 2.7.1.2 G Glucokinase
FLDMCAKM_01023 3.9e-72 yqhL P Rhodanese-like protein
FLDMCAKM_01024 1.4e-23 WQ51_02665 S Protein of unknown function (DUF3042)
FLDMCAKM_01025 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FLDMCAKM_01026 3.9e-259 glnA 6.3.1.2 E glutamine synthetase
FLDMCAKM_01027 1.4e-12
FLDMCAKM_01028 1.6e-147
FLDMCAKM_01029 1.3e-176
FLDMCAKM_01030 6.6e-93 dut S Protein conserved in bacteria
FLDMCAKM_01031 1.1e-200 S Phage integrase family
FLDMCAKM_01032 1e-66
FLDMCAKM_01033 3.3e-45 V Abi-like protein
FLDMCAKM_01035 6.4e-26 xkdA E Zn peptidase
FLDMCAKM_01036 7.6e-18 3.4.21.88 K Helix-turn-helix
FLDMCAKM_01037 8.4e-08 cro K Helix-turn-helix XRE-family like proteins
FLDMCAKM_01038 1.2e-114 S DNA binding
FLDMCAKM_01047 1.1e-10 S Domain of unknown function (DUF771)
FLDMCAKM_01048 3.3e-10
FLDMCAKM_01052 1.3e-107 recT L RecT family
FLDMCAKM_01053 4.2e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLDMCAKM_01054 4.9e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLDMCAKM_01055 1.4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FLDMCAKM_01056 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
FLDMCAKM_01057 8.9e-309 ubiB S ABC1 family
FLDMCAKM_01058 8.8e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
FLDMCAKM_01059 8.8e-170 GK ROK family
FLDMCAKM_01060 3.9e-41
FLDMCAKM_01061 4.7e-79 copY K Copper transport repressor CopY TcrY
FLDMCAKM_01063 4.2e-28 3.6.3.6 P Cation transporter/ATPase, N-terminus
FLDMCAKM_01064 3.9e-60 3.6.3.6 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
FLDMCAKM_01065 9.4e-193 3.6.3.6 P Cation transporter/ATPase, N-terminus
FLDMCAKM_01069 1.2e-143 mutR K Transcriptional activator, Rgg GadR MutR family
FLDMCAKM_01070 1.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
FLDMCAKM_01071 3.2e-229 gntT EG Gluconate
FLDMCAKM_01072 1.3e-179 K Transcriptional regulator, LacI family
FLDMCAKM_01073 1.1e-33 yneR
FLDMCAKM_01074 1.8e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
FLDMCAKM_01075 3e-93 V VanZ like family
FLDMCAKM_01076 3.8e-263 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
FLDMCAKM_01077 7.5e-100 K helix_turn_helix multiple antibiotic resistance protein
FLDMCAKM_01078 1.1e-54 fsr EGP Major Facilitator Superfamily
FLDMCAKM_01079 8.9e-46 fsr EGP Major Facilitator Superfamily
FLDMCAKM_01080 3.9e-98 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLDMCAKM_01081 7.8e-103 S CAAX protease self-immunity
FLDMCAKM_01083 2.3e-114 Q Methyltransferase domain
FLDMCAKM_01084 2.3e-21 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
FLDMCAKM_01085 6.5e-44 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
FLDMCAKM_01086 1.6e-49 K 2 iron, 2 sulfur cluster binding
FLDMCAKM_01087 0.0 mco Q Multicopper oxidase
FLDMCAKM_01088 4.3e-86 S Aminoacyl-tRNA editing domain
FLDMCAKM_01089 9.6e-66 ddaH 3.5.3.18 E PFAM amidinotransferase
FLDMCAKM_01091 1.4e-190 nhaC C Na H antiporter NhaC
FLDMCAKM_01092 3.2e-144 S Oxidoreductase family, NAD-binding Rossmann fold
FLDMCAKM_01095 5.3e-161 S Phosphotransferase system, EIIC
FLDMCAKM_01096 1.6e-23 D mRNA cleavage
FLDMCAKM_01097 1.2e-20 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
FLDMCAKM_01098 2.2e-52 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FLDMCAKM_01099 7.6e-45 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FLDMCAKM_01100 9.2e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLDMCAKM_01101 3.8e-16
FLDMCAKM_01102 3.1e-62 yjbR S YjbR
FLDMCAKM_01103 8.2e-114 S Sel1-like repeats.
FLDMCAKM_01104 1e-15
FLDMCAKM_01105 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FLDMCAKM_01106 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
FLDMCAKM_01107 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FLDMCAKM_01108 3e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FLDMCAKM_01109 2.8e-252 yifK E Amino acid permease
FLDMCAKM_01110 1.4e-289 clcA P chloride
FLDMCAKM_01111 4.5e-33 secG U Preprotein translocase
FLDMCAKM_01112 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FLDMCAKM_01113 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
FLDMCAKM_01114 5.5e-109 yxjI
FLDMCAKM_01115 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FLDMCAKM_01116 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
FLDMCAKM_01117 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
FLDMCAKM_01118 3.3e-89 K Acetyltransferase (GNAT) domain
FLDMCAKM_01119 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
FLDMCAKM_01120 5.7e-166 murB 1.3.1.98 M Cell wall formation
FLDMCAKM_01121 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FLDMCAKM_01122 2.7e-115 ybbR S YbbR-like protein
FLDMCAKM_01123 1.1e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLDMCAKM_01124 1.8e-81 uspA T universal stress protein
FLDMCAKM_01125 4.6e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLDMCAKM_01126 1.7e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FLDMCAKM_01127 1.3e-205 yeaN P Transporter, major facilitator family protein
FLDMCAKM_01128 1.9e-74 S 3-demethylubiquinone-9 3-methyltransferase
FLDMCAKM_01129 1.2e-82 nrdI F Belongs to the NrdI family
FLDMCAKM_01130 8.1e-252 yhdP S Transporter associated domain
FLDMCAKM_01131 5.7e-89 GM epimerase
FLDMCAKM_01132 2.9e-85 M1-874 K Domain of unknown function (DUF1836)
FLDMCAKM_01133 1.2e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
FLDMCAKM_01134 1.1e-264 pipD E Dipeptidase
FLDMCAKM_01135 7.2e-130
FLDMCAKM_01136 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FLDMCAKM_01137 1.6e-129 gntR K UbiC transcription regulator-associated domain protein
FLDMCAKM_01138 1.2e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
FLDMCAKM_01139 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
FLDMCAKM_01141 3.8e-96 tag 3.2.2.20 L glycosylase
FLDMCAKM_01142 1.1e-246 EGP Major facilitator Superfamily
FLDMCAKM_01143 7.4e-85 perR P Belongs to the Fur family
FLDMCAKM_01144 1.3e-246 cycA E Amino acid permease
FLDMCAKM_01145 4e-22
FLDMCAKM_01149 2e-18 K Transcriptional regulator, TetR family
FLDMCAKM_01150 5.1e-90 K Transcriptional regulator, TetR family
FLDMCAKM_01151 1.1e-77 hsp O Belongs to the small heat shock protein (HSP20) family
FLDMCAKM_01152 3.7e-85 ykhA 3.1.2.20 I Thioesterase superfamily
FLDMCAKM_01153 1.8e-65 lytE M LysM domain protein
FLDMCAKM_01154 1.2e-188 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
FLDMCAKM_01155 4.6e-236 F Permease
FLDMCAKM_01156 3e-159 sufD O Uncharacterized protein family (UPF0051)
FLDMCAKM_01157 4e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FLDMCAKM_01158 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
FLDMCAKM_01159 7.6e-110 XK27_05795 P ABC transporter permease
FLDMCAKM_01160 6.9e-142 ET Bacterial periplasmic substrate-binding proteins
FLDMCAKM_01161 1.9e-15 qacC P COG2076 Membrane transporters of cations and cationic drugs
FLDMCAKM_01162 1.2e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine
FLDMCAKM_01163 8.8e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
FLDMCAKM_01164 1.3e-205 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FLDMCAKM_01165 4.7e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FLDMCAKM_01166 1.2e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FLDMCAKM_01167 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
FLDMCAKM_01168 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
FLDMCAKM_01169 4.1e-223 nusA K Participates in both transcription termination and antitermination
FLDMCAKM_01170 1.4e-47 ylxR K Protein of unknown function (DUF448)
FLDMCAKM_01171 3.2e-50 ylxQ J ribosomal protein
FLDMCAKM_01172 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FLDMCAKM_01173 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FLDMCAKM_01174 2.6e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FLDMCAKM_01175 3.3e-183 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
FLDMCAKM_01176 5.4e-248 EGP Major facilitator Superfamily
FLDMCAKM_01178 4.6e-57 S Domain of unknown function (DUF956)
FLDMCAKM_01179 3e-170 manN G system, mannose fructose sorbose family IID component
FLDMCAKM_01180 2.7e-122 manY G PTS system
FLDMCAKM_01181 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
FLDMCAKM_01182 2.3e-181 yfeX P Peroxidase
FLDMCAKM_01183 1.2e-88 racA K Domain of unknown function (DUF1836)
FLDMCAKM_01184 3.9e-148 yitS S EDD domain protein, DegV family
FLDMCAKM_01185 5.2e-23 manA 5.3.1.8 G mannose-6-phosphate isomerase
FLDMCAKM_01186 1.7e-43 manA 5.3.1.8 G mannose-6-phosphate isomerase
FLDMCAKM_01187 6e-163 K LysR substrate binding domain
FLDMCAKM_01188 2.1e-159 MA20_14895 S Conserved hypothetical protein 698
FLDMCAKM_01189 2.4e-75 lytE M Lysin motif
FLDMCAKM_01190 5e-148 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
FLDMCAKM_01191 3.5e-210 oatA I Acyltransferase
FLDMCAKM_01192 3.3e-52
FLDMCAKM_01193 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FLDMCAKM_01194 0.0 yjcE P Sodium proton antiporter
FLDMCAKM_01195 5.2e-17 yvlA
FLDMCAKM_01196 3.2e-113 P Cobalt transport protein
FLDMCAKM_01197 2.3e-254 cbiO1 S ABC transporter, ATP-binding protein
FLDMCAKM_01198 2.9e-99 S ABC-type cobalt transport system, permease component
FLDMCAKM_01199 4.4e-180 iunH2 3.2.2.1 F nucleoside hydrolase
FLDMCAKM_01200 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
FLDMCAKM_01201 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
FLDMCAKM_01202 2.8e-32 copZ P Heavy-metal-associated domain
FLDMCAKM_01203 1.2e-100 dps P Belongs to the Dps family
FLDMCAKM_01204 4.8e-106 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
FLDMCAKM_01205 2.9e-84
FLDMCAKM_01206 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FLDMCAKM_01207 2.5e-126 pgm3 G phosphoglycerate mutase family
FLDMCAKM_01208 6e-26 qorB 1.6.5.2 GM NmrA-like family
FLDMCAKM_01209 5.9e-115 qorB 1.6.5.2 GM NmrA-like family
FLDMCAKM_01210 3.5e-67 K Bacterial regulatory helix-turn-helix protein, lysR family
FLDMCAKM_01211 1.4e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
FLDMCAKM_01212 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
FLDMCAKM_01213 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
FLDMCAKM_01214 2.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FLDMCAKM_01215 1.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FLDMCAKM_01216 1.7e-70 esbA S Family of unknown function (DUF5322)
FLDMCAKM_01217 3.2e-68 rnhA 3.1.26.4 L Ribonuclease HI
FLDMCAKM_01218 1.8e-107 XK27_02070 S Nitroreductase family
FLDMCAKM_01219 1e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
FLDMCAKM_01220 1.2e-118 yecS E ABC transporter permease
FLDMCAKM_01221 4.6e-51 L Integrase core domain
FLDMCAKM_01222 3.7e-93 L Integrase core domain
FLDMCAKM_01224 1.8e-270 nylA 3.5.1.4 J Belongs to the amidase family
FLDMCAKM_01225 1.4e-28 arcD S C4-dicarboxylate anaerobic carrier
FLDMCAKM_01226 9.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDMCAKM_01227 9.5e-200 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FLDMCAKM_01228 1.1e-109 C aldo keto reductase
FLDMCAKM_01229 2.2e-111 3.1.3.73 G phosphoglycerate mutase
FLDMCAKM_01230 3.3e-09
FLDMCAKM_01231 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FLDMCAKM_01232 1.9e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLDMCAKM_01233 9.9e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
FLDMCAKM_01234 8.5e-56 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FLDMCAKM_01235 2.5e-72 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FLDMCAKM_01236 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FLDMCAKM_01237 2.5e-92 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLDMCAKM_01238 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FLDMCAKM_01239 0.0 dnaK O Heat shock 70 kDa protein
FLDMCAKM_01240 2.1e-60 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FLDMCAKM_01241 6.7e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FLDMCAKM_01242 5.4e-62
FLDMCAKM_01243 4.7e-81 EGP Major facilitator Superfamily
FLDMCAKM_01244 1.9e-33 EGP Major facilitator Superfamily
FLDMCAKM_01245 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
FLDMCAKM_01246 4.8e-177 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FLDMCAKM_01247 6.5e-262 lysC 2.7.2.4 E Belongs to the aspartokinase family
FLDMCAKM_01248 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FLDMCAKM_01249 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FLDMCAKM_01250 1.5e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FLDMCAKM_01251 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLDMCAKM_01252 4e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FLDMCAKM_01253 3.2e-217 patA 2.6.1.1 E Aminotransferase
FLDMCAKM_01254 4.8e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLDMCAKM_01255 8.2e-225 ktrB P Potassium uptake protein
FLDMCAKM_01256 7.5e-118 ktrA P domain protein
FLDMCAKM_01257 8.6e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
FLDMCAKM_01258 1.1e-155 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FLDMCAKM_01259 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
FLDMCAKM_01261 0.0 dnaE 2.7.7.7 L DNA polymerase
FLDMCAKM_01262 1.8e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
FLDMCAKM_01263 1e-167 cvfB S S1 domain
FLDMCAKM_01264 2e-131 xerD D recombinase XerD
FLDMCAKM_01265 3.8e-66 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FLDMCAKM_01266 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FLDMCAKM_01267 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FLDMCAKM_01268 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FLDMCAKM_01269 4.1e-80 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FLDMCAKM_01270 1.5e-197 ypbB 5.1.3.1 S Helix-turn-helix domain
FLDMCAKM_01271 2.1e-274 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
FLDMCAKM_01272 1.7e-29 M Lysin motif
FLDMCAKM_01273 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
FLDMCAKM_01274 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
FLDMCAKM_01275 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
FLDMCAKM_01276 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FLDMCAKM_01277 3.4e-233 S Tetratricopeptide repeat protein
FLDMCAKM_01278 1.8e-164 xerD L Phage integrase, N-terminal SAM-like domain
FLDMCAKM_01279 2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FLDMCAKM_01280 0.0 yfmR S ABC transporter, ATP-binding protein
FLDMCAKM_01281 2e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FLDMCAKM_01282 2.5e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLDMCAKM_01283 7.7e-109 hlyIII S protein, hemolysin III
FLDMCAKM_01284 7.6e-152 DegV S EDD domain protein, DegV family
FLDMCAKM_01285 1.8e-215 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
FLDMCAKM_01286 5.5e-107 cat S Bacterial transferase hexapeptide (six repeats)
FLDMCAKM_01287 1.8e-167 ypmR E lipolytic protein G-D-S-L family
FLDMCAKM_01288 9.2e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
FLDMCAKM_01289 3.1e-36 yozE S Belongs to the UPF0346 family
FLDMCAKM_01290 3.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FLDMCAKM_01291 1.4e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLDMCAKM_01292 2e-163 dprA LU DNA protecting protein DprA
FLDMCAKM_01293 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLDMCAKM_01294 8.9e-153 D DNA integration
FLDMCAKM_01295 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
FLDMCAKM_01296 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FLDMCAKM_01297 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FLDMCAKM_01298 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FLDMCAKM_01299 1.5e-94 S Protein of unknown function (DUF1440)
FLDMCAKM_01300 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
FLDMCAKM_01301 2.3e-71 yqkB S Belongs to the HesB IscA family
FLDMCAKM_01302 3.8e-75 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
FLDMCAKM_01303 3.5e-91 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
FLDMCAKM_01304 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
FLDMCAKM_01305 3e-243 U Belongs to the purine-cytosine permease (2.A.39) family
FLDMCAKM_01306 8e-243 codA 3.5.4.1 F cytosine deaminase
FLDMCAKM_01307 0.0 oppD EP Psort location Cytoplasmic, score
FLDMCAKM_01309 1.3e-254 rarA L recombination factor protein RarA
FLDMCAKM_01310 5.8e-34 S Protein of unknown function (DUF554)
FLDMCAKM_01311 7.6e-239 yhjX P Major Facilitator Superfamily
FLDMCAKM_01312 5e-167 map 3.4.11.18 E Methionine Aminopeptidase
FLDMCAKM_01313 8.5e-78 fld C Flavodoxin
FLDMCAKM_01314 3e-75 gtcA S Teichoic acid glycosylation protein
FLDMCAKM_01316 1.8e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
FLDMCAKM_01317 1.7e-190 mocA S Oxidoreductase
FLDMCAKM_01318 4.9e-63 S Domain of unknown function (DUF4828)
FLDMCAKM_01319 4.9e-102 yvdD 3.2.2.10 S Belongs to the LOG family
FLDMCAKM_01320 8.1e-160 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
FLDMCAKM_01321 8.4e-287 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
FLDMCAKM_01322 2.3e-139 S NADPH-dependent FMN reductase
FLDMCAKM_01323 7.8e-34 yneR S Belongs to the HesB IscA family
FLDMCAKM_01324 4.8e-304 ybiT S ABC transporter, ATP-binding protein
FLDMCAKM_01325 4.9e-84 dps P Belongs to the Dps family
FLDMCAKM_01326 7.9e-105
FLDMCAKM_01327 1e-181 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FLDMCAKM_01329 3.7e-108 L Belongs to the 'phage' integrase family
FLDMCAKM_01331 1.4e-16 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
FLDMCAKM_01332 7.2e-36 doc S Fic/DOC family
FLDMCAKM_01333 2.1e-09
FLDMCAKM_01347 1.3e-10 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FLDMCAKM_01358 1.9e-12 ard S Antirestriction protein (ArdA)
FLDMCAKM_01359 9.3e-256 S Putative peptidoglycan binding domain
FLDMCAKM_01360 1.6e-85 uspA T Belongs to the universal stress protein A family
FLDMCAKM_01361 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
FLDMCAKM_01362 8.1e-157 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FLDMCAKM_01363 1.8e-60 3.2.1.23 S Domain of unknown function DUF302
FLDMCAKM_01364 8e-299 ytgP S Polysaccharide biosynthesis protein
FLDMCAKM_01365 2.2e-41
FLDMCAKM_01366 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
FLDMCAKM_01367 2.3e-125 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
FLDMCAKM_01368 6.4e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FLDMCAKM_01369 3.7e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLDMCAKM_01370 3.9e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FLDMCAKM_01371 3.2e-50
FLDMCAKM_01372 2.5e-13 S Domain of unknown function (DUF4343)
FLDMCAKM_01373 7.7e-46 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FLDMCAKM_01374 2.2e-165 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FLDMCAKM_01375 1.8e-83 csm5 L RAMP superfamily
FLDMCAKM_01376 9.6e-76 csm4 L CRISPR-associated RAMP protein, Csm4 family
FLDMCAKM_01377 2.2e-82 csm3 L RAMP superfamily
FLDMCAKM_01378 9.2e-23 csm2 L Csm2 Type III-A
FLDMCAKM_01379 4.4e-226 csm1 S CRISPR-associated protein Csm1 family
FLDMCAKM_01380 1.2e-50 cas6 S Pfam:DUF2276
FLDMCAKM_01381 7e-58 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
FLDMCAKM_01382 0.0 L Type III restriction enzyme, res subunit
FLDMCAKM_01383 2.3e-14 L Type III restriction enzyme, res subunit
FLDMCAKM_01385 2.4e-101 K DNA-templated transcription, initiation
FLDMCAKM_01386 9.5e-206 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FLDMCAKM_01387 2.5e-133 XK27_01040 S Protein of unknown function (DUF1129)
FLDMCAKM_01388 2.8e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FLDMCAKM_01389 1.7e-30 yyzM S Bacterial protein of unknown function (DUF951)
FLDMCAKM_01390 2.4e-142 spo0J K Belongs to the ParB family
FLDMCAKM_01391 1.3e-155 noc K Belongs to the ParB family
FLDMCAKM_01392 4.5e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
FLDMCAKM_01393 2.2e-144 rihC 3.2.2.1 F Nucleoside
FLDMCAKM_01394 3.8e-213 nupG F Nucleoside transporter
FLDMCAKM_01395 4.6e-188 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
FLDMCAKM_01396 2.3e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLDMCAKM_01397 6.8e-225 glnP P ABC transporter
FLDMCAKM_01398 1.1e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FLDMCAKM_01399 7.5e-76 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
FLDMCAKM_01400 3.1e-116 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
FLDMCAKM_01401 1e-133 pnuC H nicotinamide mononucleotide transporter
FLDMCAKM_01402 2.3e-298 ybeC E amino acid
FLDMCAKM_01403 2e-80 K FR47-like protein
FLDMCAKM_01404 8.5e-137 V domain protein
FLDMCAKM_01405 7.1e-96 V domain protein
FLDMCAKM_01406 3.3e-92 K Transcriptional regulator (TetR family)
FLDMCAKM_01407 7.6e-186 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
FLDMCAKM_01408 4.4e-169
FLDMCAKM_01410 4e-83 zur P Belongs to the Fur family
FLDMCAKM_01411 3.1e-104 gmk2 2.7.4.8 F Guanylate kinase
FLDMCAKM_01412 2.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
FLDMCAKM_01413 2.8e-10 yfnA E Amino Acid
FLDMCAKM_01414 5.9e-15 yfnA E Amino Acid
FLDMCAKM_01415 6.1e-15 yfnA E Amino Acid
FLDMCAKM_01416 5.5e-203 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
FLDMCAKM_01417 4.3e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
FLDMCAKM_01418 1.6e-51 cps3I G Acyltransferase family
FLDMCAKM_01419 1.1e-132 rfbJ M Glycosyl transferase family 2
FLDMCAKM_01420 3e-63
FLDMCAKM_01421 1e-44 M biosynthesis protein
FLDMCAKM_01422 5.5e-95 cps3F
FLDMCAKM_01423 1.4e-144 cps1D M Domain of unknown function (DUF4422)
FLDMCAKM_01424 4.2e-118 rfbP M Bacterial sugar transferase
FLDMCAKM_01425 5.5e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
FLDMCAKM_01426 1.3e-07
FLDMCAKM_01427 3.8e-31 S Protein of unknown function (DUF2922)
FLDMCAKM_01428 3.5e-139 yihY S Belongs to the UPF0761 family
FLDMCAKM_01429 1.5e-13 XK27_08315 M Sulfatase
FLDMCAKM_01430 9.5e-135 XK27_08315 M Sulfatase
FLDMCAKM_01431 1.1e-76 K response regulator
FLDMCAKM_01432 3e-09 sptS 2.7.13.3 T Histidine kinase
FLDMCAKM_01433 8.8e-86 sptS 2.7.13.3 T Histidine kinase
FLDMCAKM_01434 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
FLDMCAKM_01435 2.8e-102 2.3.1.128 K acetyltransferase
FLDMCAKM_01436 7.5e-135 IQ Dehydrogenase reductase
FLDMCAKM_01437 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FLDMCAKM_01438 1.1e-159 EG EamA-like transporter family
FLDMCAKM_01439 0.0 helD 3.6.4.12 L DNA helicase
FLDMCAKM_01440 4.3e-118 dedA S SNARE associated Golgi protein
FLDMCAKM_01441 9e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
FLDMCAKM_01442 4.3e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLDMCAKM_01443 3e-108 ydiN G Major Facilitator Superfamily
FLDMCAKM_01444 1.5e-41 ydiN G Major Facilitator Superfamily
FLDMCAKM_01445 3e-34 ydiN G Major Facilitator Superfamily
FLDMCAKM_01447 1.2e-208 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FLDMCAKM_01448 4.2e-103
FLDMCAKM_01449 1.3e-232 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FLDMCAKM_01450 1e-193 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
FLDMCAKM_01451 6e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLDMCAKM_01452 4.6e-216 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
FLDMCAKM_01453 2.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDMCAKM_01454 8e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FLDMCAKM_01455 7.1e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
FLDMCAKM_01456 6.7e-23 S Virus attachment protein p12 family
FLDMCAKM_01457 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
FLDMCAKM_01458 1.8e-244 S response to antibiotic
FLDMCAKM_01459 1.4e-168 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
FLDMCAKM_01460 1.2e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLDMCAKM_01461 1.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLDMCAKM_01462 1.8e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLDMCAKM_01463 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
FLDMCAKM_01464 1.1e-163 K AI-2E family transporter
FLDMCAKM_01465 9.5e-15 K Bacterial regulatory proteins, tetR family
FLDMCAKM_01466 1.2e-24 K transcriptional regulator
FLDMCAKM_01467 2.4e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
FLDMCAKM_01468 1.9e-29 ydeN S Serine hydrolase
FLDMCAKM_01472 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FLDMCAKM_01473 3.2e-118 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FLDMCAKM_01474 2.7e-166 whiA K May be required for sporulation
FLDMCAKM_01475 1e-184 ybhK S Required for morphogenesis under gluconeogenic growth conditions
FLDMCAKM_01476 7.3e-158 rapZ S Displays ATPase and GTPase activities
FLDMCAKM_01477 2.3e-201
FLDMCAKM_01478 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FLDMCAKM_01479 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FLDMCAKM_01481 1.5e-112 yfbR S HD containing hydrolase-like enzyme
FLDMCAKM_01482 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
FLDMCAKM_01483 2.4e-136 cof S haloacid dehalogenase-like hydrolase
FLDMCAKM_01484 1.4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
FLDMCAKM_01485 3.2e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FLDMCAKM_01486 1.2e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FLDMCAKM_01487 1.7e-153 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
FLDMCAKM_01488 1.3e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FLDMCAKM_01489 1.7e-75 yphH S Cupin domain
FLDMCAKM_01490 8.4e-187 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLDMCAKM_01491 3.6e-224 mtnE 2.6.1.83 E Aminotransferase
FLDMCAKM_01492 3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
FLDMCAKM_01493 6.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FLDMCAKM_01494 7.6e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
FLDMCAKM_01495 4e-161 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FLDMCAKM_01496 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FLDMCAKM_01497 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
FLDMCAKM_01498 4.1e-53 KT PspC domain protein
FLDMCAKM_01499 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FLDMCAKM_01500 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FLDMCAKM_01501 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLDMCAKM_01502 1.2e-102 comFC S Competence protein
FLDMCAKM_01503 8.5e-251 comFA L Helicase C-terminal domain protein
FLDMCAKM_01504 9e-113 yvyE 3.4.13.9 S YigZ family
FLDMCAKM_01505 6.4e-38
FLDMCAKM_01506 0.0 ydaO E amino acid
FLDMCAKM_01507 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FLDMCAKM_01508 5.6e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FLDMCAKM_01509 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FLDMCAKM_01510 0.0 uup S ABC transporter, ATP-binding protein
FLDMCAKM_01511 2.3e-173 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FLDMCAKM_01512 9.7e-92 bioY S BioY family
FLDMCAKM_01513 7.6e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
FLDMCAKM_01514 2.3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
FLDMCAKM_01515 3.4e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FLDMCAKM_01516 1.8e-262 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
FLDMCAKM_01517 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FLDMCAKM_01518 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FLDMCAKM_01519 1.7e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FLDMCAKM_01520 2.7e-129 IQ reductase
FLDMCAKM_01521 3.1e-170 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
FLDMCAKM_01522 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLDMCAKM_01523 2.4e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLDMCAKM_01524 4.1e-72 marR K Transcriptional regulator, MarR family
FLDMCAKM_01525 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FLDMCAKM_01527 5.4e-192 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FLDMCAKM_01528 1.5e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
FLDMCAKM_01529 6e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
FLDMCAKM_01530 1.7e-215 arcT 2.6.1.1 E Aminotransferase
FLDMCAKM_01531 7.1e-214 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
FLDMCAKM_01532 1.5e-256 E Arginine ornithine antiporter
FLDMCAKM_01533 1e-237 arcA 3.5.3.6 E Arginine
FLDMCAKM_01534 2.5e-161 arcC 2.7.2.2 E Belongs to the carbamate kinase family
FLDMCAKM_01535 2.4e-127 cobB K SIR2 family
FLDMCAKM_01536 1.1e-186
FLDMCAKM_01537 1.4e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
FLDMCAKM_01538 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
FLDMCAKM_01539 0.0 helD 3.6.4.12 L DNA helicase
FLDMCAKM_01540 5.8e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
FLDMCAKM_01541 3.7e-154 metQ_4 P Belongs to the nlpA lipoprotein family
FLDMCAKM_01543 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
FLDMCAKM_01544 1e-24 phaG GT1 I carboxylic ester hydrolase activity
FLDMCAKM_01545 1.7e-85 K Transcriptional regulator
FLDMCAKM_01546 7.5e-69 K Transcriptional regulator
FLDMCAKM_01548 3.9e-110
FLDMCAKM_01549 9.8e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
FLDMCAKM_01550 3.2e-164 K LysR substrate binding domain
FLDMCAKM_01551 3.1e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
FLDMCAKM_01552 8.5e-292 scrB 3.2.1.26 GH32 G invertase
FLDMCAKM_01553 6.8e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
FLDMCAKM_01554 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
FLDMCAKM_01555 1.4e-107 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLDMCAKM_01557 5.7e-39 nlhH_1 I Carboxylesterase family
FLDMCAKM_01558 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
FLDMCAKM_01559 2.1e-71 yqeY S YqeY-like protein
FLDMCAKM_01560 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
FLDMCAKM_01561 6.9e-78 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FLDMCAKM_01562 1.1e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
FLDMCAKM_01563 1.1e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FLDMCAKM_01564 2.4e-155 recO L Involved in DNA repair and RecF pathway recombination
FLDMCAKM_01565 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
FLDMCAKM_01566 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
FLDMCAKM_01567 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FLDMCAKM_01568 2.3e-204 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FLDMCAKM_01569 2e-255 guaD 3.5.4.3 F Amidohydrolase family
FLDMCAKM_01570 1.6e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
FLDMCAKM_01571 1.2e-35 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
FLDMCAKM_01572 2.1e-112 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FLDMCAKM_01573 1e-48 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
FLDMCAKM_01574 2.2e-54 rmeB K transcriptional regulator, MerR family
FLDMCAKM_01575 8.8e-131 ybbM S Uncharacterised protein family (UPF0014)
FLDMCAKM_01576 7.6e-112 ybbL S ABC transporter, ATP-binding protein
FLDMCAKM_01577 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
FLDMCAKM_01578 1.1e-34 S Protein of unknown function (DUF4256)
FLDMCAKM_01579 2e-15 K DNA-binding helix-turn-helix protein
FLDMCAKM_01580 2.9e-103 dedA S SNARE-like domain protein
FLDMCAKM_01581 5.7e-25 S Protein of unknown function (DUF1461)
FLDMCAKM_01582 5.6e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FLDMCAKM_01583 1.2e-97 yutD S Protein of unknown function (DUF1027)
FLDMCAKM_01584 2e-109 S Calcineurin-like phosphoesterase
FLDMCAKM_01585 1.4e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FLDMCAKM_01586 1.5e-158 ytxK 2.1.1.72 L N-6 DNA Methylase
FLDMCAKM_01588 1.7e-14
FLDMCAKM_01590 8.2e-15 NU general secretion pathway protein
FLDMCAKM_01591 4.2e-47 comGC U competence protein ComGC
FLDMCAKM_01592 3.3e-157 comGB NU type II secretion system
FLDMCAKM_01593 1.3e-176 comGA NU Type II IV secretion system protein
FLDMCAKM_01594 3.7e-106 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
FLDMCAKM_01595 0.0 pepN 3.4.11.2 E aminopeptidase
FLDMCAKM_01596 2.7e-149 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
FLDMCAKM_01597 6.7e-53 S Mazg nucleotide pyrophosphohydrolase
FLDMCAKM_01598 2.3e-136 E GDSL-like Lipase/Acylhydrolase family
FLDMCAKM_01599 1.5e-123 C nitroreductase
FLDMCAKM_01600 1.9e-146 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
FLDMCAKM_01601 4.8e-16 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
FLDMCAKM_01602 8e-40 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
FLDMCAKM_01603 7.7e-188 sucD 6.2.1.5 C CoA-ligase
FLDMCAKM_01604 5.7e-19 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
FLDMCAKM_01605 8.4e-179 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDMCAKM_01606 4.7e-244 glpT G Major Facilitator Superfamily
FLDMCAKM_01607 9.7e-130 qmcA O prohibitin homologues
FLDMCAKM_01609 3.1e-75 uspA T universal stress protein
FLDMCAKM_01610 7.9e-59
FLDMCAKM_01611 1.6e-18
FLDMCAKM_01612 1.8e-156
FLDMCAKM_01613 8.4e-75 K Transcriptional regulator
FLDMCAKM_01614 2.9e-184 D Alpha beta
FLDMCAKM_01615 1.6e-73 O OsmC-like protein
FLDMCAKM_01616 4.9e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
FLDMCAKM_01617 4.8e-46 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
FLDMCAKM_01618 9.2e-182 nifS 2.8.1.7 E DegT/DnrJ/EryC1/StrS aminotransferase family
FLDMCAKM_01619 2.7e-202 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FLDMCAKM_01620 4.1e-270 nadB 1.3.5.4, 1.4.3.16 H L-aspartate oxidase
FLDMCAKM_01621 0.0 lacL 3.2.1.23 G hydrolase activity, hydrolyzing O-glycosyl compounds
FLDMCAKM_01622 1e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
FLDMCAKM_01623 4.3e-36 rafA 3.2.1.22 G alpha-galactosidase
FLDMCAKM_01624 8.4e-125 rafA 3.2.1.22 G alpha-galactosidase
FLDMCAKM_01625 1.4e-06 S EpsG family
FLDMCAKM_01626 1e-80
FLDMCAKM_01627 3.1e-62 S COG0463 Glycosyltransferases involved in cell wall biogenesis
FLDMCAKM_01628 1.6e-83 GT4 G Glycosyl transferase 4-like
FLDMCAKM_01629 5.7e-88 capM M Bacterial sugar transferase
FLDMCAKM_01630 2.5e-141 ywqE 3.1.3.48 GM PHP domain protein
FLDMCAKM_01631 1.1e-114 ywqD 2.7.10.1 D Capsular exopolysaccharide family
FLDMCAKM_01632 9.7e-130 epsB M biosynthesis protein
FLDMCAKM_01633 2.8e-169 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FLDMCAKM_01634 4.1e-209 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
FLDMCAKM_01635 1.8e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FLDMCAKM_01636 5.7e-46 citD C Covalent carrier of the coenzyme of citrate lyase
FLDMCAKM_01637 5.1e-162 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
FLDMCAKM_01638 1.5e-286 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
FLDMCAKM_01639 7.8e-258 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
FLDMCAKM_01640 9.9e-146 ydjP I Alpha/beta hydrolase family
FLDMCAKM_01641 9.1e-145 KT YcbB domain
FLDMCAKM_01642 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
FLDMCAKM_01643 3.1e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
FLDMCAKM_01644 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FLDMCAKM_01645 7.6e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
FLDMCAKM_01646 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
FLDMCAKM_01647 6.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FLDMCAKM_01648 1.5e-55 yabA L Involved in initiation control of chromosome replication
FLDMCAKM_01649 1e-190 holB 2.7.7.7 L DNA polymerase III
FLDMCAKM_01650 1.3e-51 yaaQ S Cyclic-di-AMP receptor
FLDMCAKM_01651 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FLDMCAKM_01652 2.4e-21 S Protein of unknown function (DUF2508)
FLDMCAKM_01653 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FLDMCAKM_01654 1.4e-39 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FLDMCAKM_01655 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FLDMCAKM_01657 2.4e-79 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FLDMCAKM_01658 2e-35 nrdH O Glutaredoxin
FLDMCAKM_01659 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLDMCAKM_01660 5.6e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLDMCAKM_01661 3.3e-245 brnQ U Component of the transport system for branched-chain amino acids
FLDMCAKM_01662 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
FLDMCAKM_01663 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLDMCAKM_01664 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
FLDMCAKM_01665 1.2e-175 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
FLDMCAKM_01666 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
FLDMCAKM_01667 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FLDMCAKM_01668 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FLDMCAKM_01669 6.6e-243 steT E amino acid
FLDMCAKM_01670 7.4e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FLDMCAKM_01671 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FLDMCAKM_01672 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
FLDMCAKM_01673 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
FLDMCAKM_01674 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FLDMCAKM_01675 4.5e-103 sigH K Belongs to the sigma-70 factor family
FLDMCAKM_01676 6.4e-134 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLDMCAKM_01677 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FLDMCAKM_01678 3.4e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
FLDMCAKM_01679 7.8e-100 ywlG S Belongs to the UPF0340 family
FLDMCAKM_01680 3.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLDMCAKM_01681 7.2e-206 yacL S domain protein
FLDMCAKM_01682 1.4e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FLDMCAKM_01683 1.3e-96 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
FLDMCAKM_01684 3.5e-54 HA62_12640 S GCN5-related N-acetyl-transferase
FLDMCAKM_01685 4.6e-123 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FLDMCAKM_01686 3.1e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
FLDMCAKM_01687 4e-264 pepC 3.4.22.40 E Peptidase C1-like family
FLDMCAKM_01688 8.1e-165 I alpha/beta hydrolase fold
FLDMCAKM_01689 6.1e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FLDMCAKM_01690 2.3e-168 mleP2 S Sodium Bile acid symporter family
FLDMCAKM_01691 4e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
FLDMCAKM_01692 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
FLDMCAKM_01694 3.1e-83 ydcK S Belongs to the SprT family
FLDMCAKM_01695 0.0 yhgF K Tex-like protein N-terminal domain protein
FLDMCAKM_01696 2.2e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FLDMCAKM_01697 2.9e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FLDMCAKM_01698 5.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
FLDMCAKM_01699 3.7e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
FLDMCAKM_01700 1.7e-111
FLDMCAKM_01703 9.6e-146 yjjH S Calcineurin-like phosphoesterase
FLDMCAKM_01704 7.6e-256 dtpT U amino acid peptide transporter
FLDMCAKM_01705 1.2e-163 D nuclear chromosome segregation
FLDMCAKM_01706 8.1e-74 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
FLDMCAKM_01707 5.8e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FLDMCAKM_01708 1.6e-68 psiE S Phosphate-starvation-inducible E
FLDMCAKM_01709 3.5e-157 L hmm pf00665
FLDMCAKM_01710 1.3e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLDMCAKM_01711 5.5e-158 P Belongs to the nlpA lipoprotein family
FLDMCAKM_01712 8.4e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLDMCAKM_01713 2.1e-115 S Protein of unknown function (DUF554)
FLDMCAKM_01714 2.2e-92 P Cadmium resistance transporter
FLDMCAKM_01715 3.9e-33 feoA P FeoA domain
FLDMCAKM_01716 2.5e-144 sufC O FeS assembly ATPase SufC
FLDMCAKM_01717 7.6e-244 sufD O FeS assembly protein SufD
FLDMCAKM_01718 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLDMCAKM_01719 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
FLDMCAKM_01720 1.1e-272 sufB O assembly protein SufB
FLDMCAKM_01721 1.1e-38 fecB P Periplasmic binding protein
FLDMCAKM_01722 4.6e-123 fecB P Periplasmic binding protein
FLDMCAKM_01723 1.1e-234 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
FLDMCAKM_01724 5.1e-251 nox C NADH oxidase
FLDMCAKM_01725 1.1e-27 devA 3.6.3.25 V ABC transporter, ATP-binding protein
FLDMCAKM_01726 9.1e-264 npr 1.11.1.1 C NADH oxidase
FLDMCAKM_01727 1.1e-107 S hydrolase
FLDMCAKM_01728 3.1e-16 S hydrolase
FLDMCAKM_01729 0.0 asnB 6.3.5.4 E Aluminium induced protein
FLDMCAKM_01730 3e-17 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
FLDMCAKM_01731 7.3e-13
FLDMCAKM_01732 1.1e-181 scrR3 K Transcriptional regulator, LacI family
FLDMCAKM_01733 5e-78 F Nucleoside 2-deoxyribosyltransferase
FLDMCAKM_01734 2e-85
FLDMCAKM_01736 3.5e-08
FLDMCAKM_01738 3.6e-57
FLDMCAKM_01740 4.7e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
FLDMCAKM_01741 1.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FLDMCAKM_01742 6.9e-161 ytbE 1.1.1.346 S Aldo keto reductase
FLDMCAKM_01743 1.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
FLDMCAKM_01744 2.1e-82 K GNAT family
FLDMCAKM_01746 2e-60 azlD S branched-chain amino acid
FLDMCAKM_01747 4.6e-136 azlC E AzlC protein
FLDMCAKM_01748 5.5e-202 dacA 3.4.16.4 M Belongs to the peptidase S11 family
FLDMCAKM_01749 1.4e-204 hpk31 2.7.13.3 T Histidine kinase
FLDMCAKM_01750 1e-122 K response regulator
FLDMCAKM_01751 7.4e-94 S Cupin superfamily (DUF985)
FLDMCAKM_01752 2.1e-125 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
FLDMCAKM_01753 1.7e-62 M Glycosyltransferase like family 2
FLDMCAKM_01754 4.3e-29 GM Glycosyltransferase like family 2
FLDMCAKM_01755 3.3e-31 M Glycosyltransferase, group 2 family protein
FLDMCAKM_01756 1.7e-151 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
FLDMCAKM_01758 4e-40 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
FLDMCAKM_01759 5.3e-78 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
FLDMCAKM_01760 6.5e-30 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
FLDMCAKM_01761 3e-70 ydjP I Alpha/beta hydrolase family
FLDMCAKM_01762 4.4e-106 L Integrase
FLDMCAKM_01763 1.5e-90 P Cadmium resistance transporter
FLDMCAKM_01766 4.9e-29 C Aldo keto reductase
FLDMCAKM_01767 6.9e-23 C reductase
FLDMCAKM_01768 9.3e-39 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDMCAKM_01771 1.9e-74 S Alpha/beta hydrolase family
FLDMCAKM_01772 7.8e-120 pnb C nitroreductase
FLDMCAKM_01773 2.6e-20 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
FLDMCAKM_01775 1.2e-234 P Sodium:sulfate symporter transmembrane region
FLDMCAKM_01776 5.8e-89 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FLDMCAKM_01777 5e-50 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FLDMCAKM_01778 3.5e-263 frdC 1.3.5.4 C FAD binding domain
FLDMCAKM_01779 3.4e-258 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FLDMCAKM_01780 1.6e-52 ydbD P Catalase
FLDMCAKM_01781 1.9e-51 ydbD P Catalase
FLDMCAKM_01782 1.2e-223 citP C Na citrate symporter
FLDMCAKM_01783 1.3e-202 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
FLDMCAKM_01784 8.6e-165 L Transposase and inactivated derivatives, IS30 family
FLDMCAKM_01785 3.1e-72 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
FLDMCAKM_01787 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FLDMCAKM_01788 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FLDMCAKM_01789 1.9e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FLDMCAKM_01790 2.5e-115 radC L DNA repair protein
FLDMCAKM_01791 1.2e-180 mreB D cell shape determining protein MreB
FLDMCAKM_01792 1.4e-145 mreC M Involved in formation and maintenance of cell shape
FLDMCAKM_01793 6.6e-93 mreD M rod shape-determining protein MreD
FLDMCAKM_01794 1.4e-108 glnP P ABC transporter permease
FLDMCAKM_01795 9e-113 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FLDMCAKM_01796 3.5e-160 aatB ET ABC transporter substrate-binding protein
FLDMCAKM_01797 1.5e-231 ymfF S Peptidase M16 inactive domain protein
FLDMCAKM_01798 3.8e-251 ymfH S Peptidase M16
FLDMCAKM_01799 1.1e-93 ymfM S Helix-turn-helix domain
FLDMCAKM_01800 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLDMCAKM_01801 4.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
FLDMCAKM_01802 4.2e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FLDMCAKM_01803 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
FLDMCAKM_01804 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FLDMCAKM_01805 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FLDMCAKM_01806 1.9e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FLDMCAKM_01807 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FLDMCAKM_01808 7.5e-177 2.4.2.29 F queuine tRNA-ribosyltransferase activity
FLDMCAKM_01809 5.5e-42 yajC U Preprotein translocase
FLDMCAKM_01810 3.4e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
FLDMCAKM_01811 1.2e-231 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FLDMCAKM_01812 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FLDMCAKM_01813 1.2e-42 yrzL S Belongs to the UPF0297 family
FLDMCAKM_01814 1.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FLDMCAKM_01815 5.7e-33 yrzB S Belongs to the UPF0473 family
FLDMCAKM_01816 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLDMCAKM_01817 6.1e-91 cvpA S Colicin V production protein
FLDMCAKM_01818 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FLDMCAKM_01819 1.1e-52 trxA O Belongs to the thioredoxin family
FLDMCAKM_01820 1e-224 clcA_2 P Chloride transporter, ClC family
FLDMCAKM_01821 4e-116 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FLDMCAKM_01822 8.7e-93 yslB S Protein of unknown function (DUF2507)
FLDMCAKM_01823 1.4e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FLDMCAKM_01824 9.8e-67 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLDMCAKM_01825 2e-94 S Phosphoesterase
FLDMCAKM_01826 1.2e-149 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
FLDMCAKM_01827 5.3e-156 ykuT M mechanosensitive ion channel
FLDMCAKM_01828 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FLDMCAKM_01829 4.9e-70
FLDMCAKM_01830 3.5e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FLDMCAKM_01831 4.5e-183 ccpA K catabolite control protein A
FLDMCAKM_01832 1.1e-81
FLDMCAKM_01833 6.3e-134 yebC K Transcriptional regulatory protein
FLDMCAKM_01834 4.9e-84 mltD CBM50 M PFAM NLP P60 protein
FLDMCAKM_01835 9e-43 S Alpha beta hydrolase
FLDMCAKM_01836 2e-79 S Alpha beta hydrolase
FLDMCAKM_01837 3.6e-106 1.6.5.2 GM NAD(P)H-binding
FLDMCAKM_01838 2.6e-149 S Sucrose-6F-phosphate phosphohydrolase
FLDMCAKM_01840 5.7e-243 dtpT U amino acid peptide transporter
FLDMCAKM_01842 4e-49 yebR 1.8.4.14 T GAF domain
FLDMCAKM_01843 5.9e-133 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLDMCAKM_01844 2e-94 metI P ABC transporter permease
FLDMCAKM_01845 1.5e-118 metQ_4 P Belongs to the nlpA lipoprotein family
FLDMCAKM_01846 1.1e-80 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FLDMCAKM_01847 1.8e-104 IQ reductase
FLDMCAKM_01848 1.9e-102 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
FLDMCAKM_01849 5.3e-102 pnuC H nicotinamide mononucleotide transporter
FLDMCAKM_01850 1.4e-21 2.7.6.5 T Region found in RelA / SpoT proteins
FLDMCAKM_01851 1.2e-267 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
FLDMCAKM_01852 1.9e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
FLDMCAKM_01853 8.9e-83 F Hydrolase, NUDIX family
FLDMCAKM_01854 2.6e-211 S Type IV secretion-system coupling protein DNA-binding domain
FLDMCAKM_01855 0.0 tetP J elongation factor G
FLDMCAKM_01856 5.5e-152 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FLDMCAKM_01857 3.6e-08 narK P Major Facilitator Superfamily
FLDMCAKM_01858 2.5e-58 narK P Major Facilitator Superfamily
FLDMCAKM_01859 6.9e-116 narK P Major Facilitator Superfamily
FLDMCAKM_01860 4.4e-58 yitW S Iron-sulfur cluster assembly protein
FLDMCAKM_01861 5.2e-159 hipB K Helix-turn-helix
FLDMCAKM_01862 1.4e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
FLDMCAKM_01863 2.2e-229 ndh 1.6.99.3 C NADH dehydrogenase
FLDMCAKM_01864 8e-54 yitW S Iron-sulfur cluster assembly protein
FLDMCAKM_01865 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
FLDMCAKM_01866 9.8e-255 XK27_04775 S PAS domain
FLDMCAKM_01867 2.8e-138 EG EamA-like transporter family
FLDMCAKM_01868 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FLDMCAKM_01869 2.7e-213 2.1.1.14 E methionine synthase, vitamin-B12 independent
FLDMCAKM_01870 1.1e-23 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
FLDMCAKM_01871 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
FLDMCAKM_01872 1e-38 mdt(A) EGP Major facilitator Superfamily
FLDMCAKM_01873 0.0 copB 3.6.3.4 P P-type ATPase
FLDMCAKM_01874 6.5e-75 K Copper transport repressor CopY TcrY
FLDMCAKM_01875 2.8e-235 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FLDMCAKM_01876 5.2e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
FLDMCAKM_01877 3.3e-217 yceI EGP Major facilitator Superfamily
FLDMCAKM_01878 1e-56 trxA1 O Belongs to the thioredoxin family
FLDMCAKM_01879 4.9e-140 terC P membrane
FLDMCAKM_01880 4.6e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FLDMCAKM_01881 1.1e-169 corA P CorA-like Mg2+ transporter protein
FLDMCAKM_01882 2e-32 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
FLDMCAKM_01883 8.7e-119 J 2'-5' RNA ligase superfamily
FLDMCAKM_01884 1.3e-131 XK27_07210 6.1.1.6 S B3 4 domain
FLDMCAKM_01885 2.8e-193 adhP 1.1.1.1 C alcohol dehydrogenase
FLDMCAKM_01886 5.3e-78 ctsR K Belongs to the CtsR family
FLDMCAKM_01887 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
FLDMCAKM_01888 1.3e-105 K Bacterial regulatory proteins, tetR family
FLDMCAKM_01889 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLDMCAKM_01890 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLDMCAKM_01891 5.6e-135 puuD S peptidase C26
FLDMCAKM_01892 3.5e-211 ykiI
FLDMCAKM_01893 3.6e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
FLDMCAKM_01894 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FLDMCAKM_01895 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FLDMCAKM_01896 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FLDMCAKM_01897 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
FLDMCAKM_01898 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FLDMCAKM_01899 2e-104 rplD J Forms part of the polypeptide exit tunnel
FLDMCAKM_01900 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FLDMCAKM_01901 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FLDMCAKM_01902 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLDMCAKM_01903 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FLDMCAKM_01904 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FLDMCAKM_01905 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FLDMCAKM_01906 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
FLDMCAKM_01907 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FLDMCAKM_01908 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FLDMCAKM_01909 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FLDMCAKM_01910 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FLDMCAKM_01911 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLDMCAKM_01912 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FLDMCAKM_01913 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FLDMCAKM_01914 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FLDMCAKM_01915 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FLDMCAKM_01916 2.5e-23 rpmD J Ribosomal protein L30
FLDMCAKM_01917 2.1e-65 rplO J Binds to the 23S rRNA
FLDMCAKM_01918 7.6e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FLDMCAKM_01919 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FLDMCAKM_01920 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FLDMCAKM_01921 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
FLDMCAKM_01922 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FLDMCAKM_01923 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FLDMCAKM_01924 3.8e-168 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLDMCAKM_01925 2.8e-61 rplQ J Ribosomal protein L17
FLDMCAKM_01926 2e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLDMCAKM_01927 9.8e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLDMCAKM_01928 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLDMCAKM_01929 2.4e-144 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FLDMCAKM_01930 3.4e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FLDMCAKM_01931 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
FLDMCAKM_01932 2.3e-122 S interspecies interaction between organisms
FLDMCAKM_01933 3e-10 S interspecies interaction between organisms
FLDMCAKM_01934 1.2e-138 IQ reductase
FLDMCAKM_01935 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
FLDMCAKM_01936 8e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FLDMCAKM_01937 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FLDMCAKM_01938 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
FLDMCAKM_01939 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FLDMCAKM_01940 1.6e-165 camS S sex pheromone
FLDMCAKM_01941 6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLDMCAKM_01942 6.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FLDMCAKM_01943 7.2e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLDMCAKM_01944 7.4e-186 yegS 2.7.1.107 G Lipid kinase
FLDMCAKM_01945 7e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLDMCAKM_01946 2e-110 L Mrr N-terminal domain
FLDMCAKM_01947 2.1e-81 XK27_09620 S NADPH-dependent FMN reductase
FLDMCAKM_01948 2.1e-183 XK27_09615 S reductase
FLDMCAKM_01949 1.8e-173 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
FLDMCAKM_01950 2.5e-150 glcU U sugar transport
FLDMCAKM_01951 1.4e-249 yclK 2.7.13.3 T Histidine kinase
FLDMCAKM_01952 3.2e-130 K response regulator
FLDMCAKM_01953 1.5e-77 K Winged helix DNA-binding domain
FLDMCAKM_01954 1.6e-98 lmrA V ABC transporter, ATP-binding protein
FLDMCAKM_01955 2.3e-179 lmrA V ABC transporter, ATP-binding protein
FLDMCAKM_01956 8.5e-143 yfiC V ABC transporter
FLDMCAKM_01957 7.2e-161 mleR K LysR family transcriptional regulator
FLDMCAKM_01958 5.1e-251 yjjP S Putative threonine/serine exporter
FLDMCAKM_01959 5.2e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
FLDMCAKM_01960 1.5e-183 fruR3 K Transcriptional regulator, LacI family
FLDMCAKM_01961 1.1e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
FLDMCAKM_01962 2.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLDMCAKM_01963 9.8e-77
FLDMCAKM_01964 3e-187 K helix_turn _helix lactose operon repressor
FLDMCAKM_01965 1.7e-279 yjeM E Amino Acid
FLDMCAKM_01966 7.7e-236 kgtP EGP Sugar (and other) transporter
FLDMCAKM_01967 5.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
FLDMCAKM_01968 1.1e-58 galR K Transcriptional regulator
FLDMCAKM_01969 1.3e-18 galR K Transcriptional regulator
FLDMCAKM_01970 7.5e-86 glcU U sugar transport
FLDMCAKM_01971 2.3e-104 ahpC 1.11.1.15 O Peroxiredoxin
FLDMCAKM_01972 0.0 trxB2 1.8.1.9 C Thioredoxin domain
FLDMCAKM_01973 7.1e-252 mntH P H( )-stimulated, divalent metal cation uptake system
FLDMCAKM_01974 1.5e-21
FLDMCAKM_01975 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLDMCAKM_01976 3.1e-70 L nuclease
FLDMCAKM_01977 3.2e-161 F DNA/RNA non-specific endonuclease
FLDMCAKM_01978 3.3e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
FLDMCAKM_01979 6.4e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLDMCAKM_01980 2.6e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLDMCAKM_01981 0.0 asnB 6.3.5.4 E Asparagine synthase
FLDMCAKM_01982 7.8e-221 lysP E amino acid
FLDMCAKM_01983 7e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
FLDMCAKM_01984 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FLDMCAKM_01985 2.5e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FLDMCAKM_01986 1.3e-135 jag S R3H domain protein
FLDMCAKM_01987 7.5e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FLDMCAKM_01988 1.9e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FLDMCAKM_01989 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
FLDMCAKM_01991 1.5e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FLDMCAKM_01992 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FLDMCAKM_01993 2.2e-34 yaaA S S4 domain protein YaaA
FLDMCAKM_01994 1.6e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLDMCAKM_01995 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLDMCAKM_01996 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLDMCAKM_01997 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
FLDMCAKM_01998 3.5e-89 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FLDMCAKM_01999 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FLDMCAKM_02000 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
FLDMCAKM_02001 1.2e-74 rplI J Binds to the 23S rRNA
FLDMCAKM_02002 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
FLDMCAKM_02003 3.3e-206 lmrP E Major Facilitator Superfamily
FLDMCAKM_02004 2.3e-59
FLDMCAKM_02007 8.9e-130 K response regulator
FLDMCAKM_02008 0.0 vicK 2.7.13.3 T Histidine kinase
FLDMCAKM_02009 1.1e-237 yycH S YycH protein
FLDMCAKM_02010 8.8e-142 yycI S YycH protein
FLDMCAKM_02011 1.3e-153 vicX 3.1.26.11 S domain protein
FLDMCAKM_02012 4.6e-198 htrA 3.4.21.107 O serine protease
FLDMCAKM_02013 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FLDMCAKM_02014 4.1e-69 K Transcriptional regulator
FLDMCAKM_02015 2.4e-175 malR K Transcriptional regulator, LacI family
FLDMCAKM_02016 8.7e-251 malT G Major Facilitator
FLDMCAKM_02017 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
FLDMCAKM_02018 2.2e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
FLDMCAKM_02019 5.3e-108 ysdA CP transmembrane transport
FLDMCAKM_02020 7.5e-11 ysdA CP ABC-type Na efflux pump, permease component
FLDMCAKM_02021 2.3e-16 natA S ABC transporter, ATP-binding protein
FLDMCAKM_02023 5.5e-16 natA S ABC transporter, ATP-binding protein
FLDMCAKM_02024 6.9e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
FLDMCAKM_02025 4.3e-79 D Alpha beta
FLDMCAKM_02026 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLDMCAKM_02027 1.7e-21 fucP G Major Facilitator Superfamily
FLDMCAKM_02028 4.9e-260 G PTS system Galactitol-specific IIC component
FLDMCAKM_02029 9.3e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLDMCAKM_02030 2.9e-31 atl 3.2.1.96, 3.5.1.28 GH73 M domain, Protein
FLDMCAKM_02031 5e-50 4.4.1.8 E Aminotransferase, class I
FLDMCAKM_02032 7.9e-80 4.4.1.8 E Aminotransferase, class I
FLDMCAKM_02033 2e-35 M Protein of unknown function (DUF3737)
FLDMCAKM_02034 4.2e-163 P secondary active sulfate transmembrane transporter activity
FLDMCAKM_02035 2.5e-66 apt 2.4.2.7 F Phosphoribosyl transferase domain
FLDMCAKM_02036 4.3e-245 cycA E Amino acid permease
FLDMCAKM_02037 9.6e-250 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
FLDMCAKM_02038 9.6e-104 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
FLDMCAKM_02039 1.4e-27 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FLDMCAKM_02040 1.4e-50 3.2.1.4 GH5,GH9 M domain protein
FLDMCAKM_02041 1.2e-92
FLDMCAKM_02042 7.3e-23 S Small integral membrane protein (DUF2273)
FLDMCAKM_02043 2e-68 S cog cog1302
FLDMCAKM_02044 1.3e-11 S Transglycosylase associated protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)