ORF_ID e_value Gene_name EC_number CAZy COGs Description
HEFJEAGE_00001 3.4e-252 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HEFJEAGE_00002 2.6e-64
HEFJEAGE_00003 9.1e-210 pbuX F xanthine permease
HEFJEAGE_00004 5e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEFJEAGE_00005 4.4e-203 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEFJEAGE_00006 2.4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HEFJEAGE_00007 3.4e-39 S HicA toxin of bacterial toxin-antitoxin,
HEFJEAGE_00008 5.8e-64 S HicB family
HEFJEAGE_00009 2.1e-204 KLT Protein kinase domain
HEFJEAGE_00010 1.9e-189 KLT Protein kinase domain
HEFJEAGE_00011 1.5e-286 V ABC-type multidrug transport system, ATPase and permease components
HEFJEAGE_00012 5.3e-147 K Transcriptional regulator
HEFJEAGE_00013 2.2e-241 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEFJEAGE_00016 2.4e-131 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HEFJEAGE_00017 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEFJEAGE_00018 2.6e-127 tcyB E ABC transporter
HEFJEAGE_00020 7.4e-130 2.4.2.3 F Phosphorylase superfamily
HEFJEAGE_00021 6.2e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
HEFJEAGE_00022 2.5e-159 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HEFJEAGE_00023 1.2e-31 mmuP E amino acid
HEFJEAGE_00024 3.6e-166 mmuP E amino acid
HEFJEAGE_00025 1.6e-174 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HEFJEAGE_00026 8.6e-78 ywhH S Aminoacyl-tRNA editing domain
HEFJEAGE_00027 2.8e-07 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Maltose acetyltransferase
HEFJEAGE_00028 3.3e-77 K DNA-binding transcription factor activity
HEFJEAGE_00029 4.6e-188 ansA 3.5.1.1 EJ L-asparaginase, type I
HEFJEAGE_00030 3.8e-47 Q phosphatase activity
HEFJEAGE_00031 4.8e-93 S Sucrose-6F-phosphate phosphohydrolase
HEFJEAGE_00032 7.5e-80 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEFJEAGE_00033 1.2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEFJEAGE_00034 2.6e-38 L the current gene model (or a revised gene model) may contain a frame shift
HEFJEAGE_00035 1.4e-144 L the current gene model (or a revised gene model) may contain a frame shift
HEFJEAGE_00036 1.3e-107 pncA Q Isochorismatase family
HEFJEAGE_00037 2.2e-107
HEFJEAGE_00038 2e-42 L Membrane
HEFJEAGE_00039 7.5e-146 2.7.7.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
HEFJEAGE_00040 2.7e-249 L Putative transposase DNA-binding domain
HEFJEAGE_00041 4.1e-41 S Enterocin A Immunity
HEFJEAGE_00043 2.9e-116 E peptidase
HEFJEAGE_00044 5e-137 V ABC-2 type transporter
HEFJEAGE_00045 9.9e-129 V ATPases associated with a variety of cellular activities
HEFJEAGE_00046 6.5e-75 KLT Protein kinase domain
HEFJEAGE_00047 4.3e-118
HEFJEAGE_00049 3.3e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEFJEAGE_00050 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
HEFJEAGE_00051 1.6e-103 S TPM domain
HEFJEAGE_00052 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HEFJEAGE_00053 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEFJEAGE_00054 1.2e-148 tatD L hydrolase, TatD family
HEFJEAGE_00055 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEFJEAGE_00056 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEFJEAGE_00057 6.4e-38 veg S Biofilm formation stimulator VEG
HEFJEAGE_00058 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HEFJEAGE_00059 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEFJEAGE_00060 4e-48
HEFJEAGE_00061 6.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEFJEAGE_00062 6.3e-254 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEFJEAGE_00063 2.5e-65 S Domain of unknown function (DUF1934)
HEFJEAGE_00064 1.1e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEFJEAGE_00065 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEFJEAGE_00066 1.3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEFJEAGE_00067 1.6e-41 rpmE2 J Ribosomal protein L31
HEFJEAGE_00068 2.7e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEFJEAGE_00069 8.2e-239 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEFJEAGE_00070 9.4e-71 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEFJEAGE_00071 1.2e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEFJEAGE_00072 2e-126 S (CBS) domain
HEFJEAGE_00073 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEFJEAGE_00074 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEFJEAGE_00075 3.2e-34 yabO J S4 domain protein
HEFJEAGE_00076 1.5e-59 divIC D Septum formation initiator
HEFJEAGE_00077 7.5e-61 yabR J S1 RNA binding domain
HEFJEAGE_00078 3e-248 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEFJEAGE_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEFJEAGE_00080 5.3e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEFJEAGE_00081 5e-301 E ABC transporter, substratebinding protein
HEFJEAGE_00082 1.3e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HEFJEAGE_00083 1.1e-197 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEFJEAGE_00084 2.5e-278 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HEFJEAGE_00086 1.5e-138 T diguanylate cyclase activity
HEFJEAGE_00088 4.1e-22 metY 2.5.1.49 E o-acetylhomoserine
HEFJEAGE_00089 5e-218 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HEFJEAGE_00090 4.1e-107 XK27_00160 S Domain of unknown function (DUF5052)
HEFJEAGE_00094 2.7e-82 yebR 1.8.4.14 T GAF domain-containing protein
HEFJEAGE_00095 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEFJEAGE_00097 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFJEAGE_00098 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFJEAGE_00099 9e-08 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HEFJEAGE_00102 1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEFJEAGE_00103 3.5e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEFJEAGE_00104 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEFJEAGE_00105 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HEFJEAGE_00106 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEFJEAGE_00107 1.6e-106 rplD J Forms part of the polypeptide exit tunnel
HEFJEAGE_00108 8.3e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEFJEAGE_00109 2.8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEFJEAGE_00110 4.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEFJEAGE_00111 8.9e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEFJEAGE_00112 9.4e-121 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEFJEAGE_00113 1.9e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEFJEAGE_00114 3.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HEFJEAGE_00115 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEFJEAGE_00116 1.6e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEFJEAGE_00117 4.5e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEFJEAGE_00118 9.3e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEFJEAGE_00119 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEFJEAGE_00120 2.8e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEFJEAGE_00121 5.7e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEFJEAGE_00122 1.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEFJEAGE_00123 1.3e-24 rpmD J Ribosomal protein L30
HEFJEAGE_00124 1.8e-72 rplO J Binds to the 23S rRNA
HEFJEAGE_00125 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEFJEAGE_00126 5.9e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEFJEAGE_00127 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEFJEAGE_00128 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEFJEAGE_00129 1.4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEFJEAGE_00130 5.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFJEAGE_00131 1.3e-61 rplQ J Ribosomal protein L17
HEFJEAGE_00132 7.4e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEFJEAGE_00133 4.4e-163 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEFJEAGE_00134 2.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEFJEAGE_00135 6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEFJEAGE_00136 4.2e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEFJEAGE_00137 3.9e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HEFJEAGE_00138 3.5e-23
HEFJEAGE_00139 1.6e-45
HEFJEAGE_00140 3.4e-186 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00141 1.2e-12 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00142 1.6e-119 XK27_07525 3.6.1.55 F NUDIX domain
HEFJEAGE_00143 7.2e-52 EGP Major facilitator Superfamily
HEFJEAGE_00144 9.3e-48 EGP Major facilitator Superfamily
HEFJEAGE_00145 1.7e-90 S Phosphatidylethanolamine-binding protein
HEFJEAGE_00148 8.5e-226 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HEFJEAGE_00149 3.7e-164 pfoS S Phosphotransferase system, EIIC
HEFJEAGE_00152 1.4e-56 oppA2 E ABC transporter, substratebinding protein
HEFJEAGE_00153 4.9e-215
HEFJEAGE_00154 1e-198
HEFJEAGE_00155 3.9e-125 gntR1 K UTRA
HEFJEAGE_00156 9.1e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEFJEAGE_00157 1.5e-261 epsU S Polysaccharide biosynthesis protein
HEFJEAGE_00158 1.4e-133 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEFJEAGE_00159 1e-204 csaB M Glycosyl transferases group 1
HEFJEAGE_00160 1.2e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HEFJEAGE_00161 3.3e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEFJEAGE_00162 0.0 pacL 3.6.3.8 P P-type ATPase
HEFJEAGE_00164 2.5e-10
HEFJEAGE_00165 3.9e-110 V ABC transporter
HEFJEAGE_00166 1.8e-89 ydcK S Belongs to the SprT family
HEFJEAGE_00168 9.1e-102 S ECF transporter, substrate-specific component
HEFJEAGE_00169 1.3e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HEFJEAGE_00170 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HEFJEAGE_00171 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEFJEAGE_00172 1.3e-191 camS S sex pheromone
HEFJEAGE_00173 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEFJEAGE_00174 7.9e-266 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEFJEAGE_00175 3.2e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEFJEAGE_00176 1.5e-169 yegS 2.7.1.107 G Lipid kinase
HEFJEAGE_00177 4e-117 S Protein of unknown function (DUF1211)
HEFJEAGE_00178 4.8e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEFJEAGE_00179 2.2e-159 L Mrr N-terminal domain
HEFJEAGE_00180 4.9e-119 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HEFJEAGE_00181 4.2e-98 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HEFJEAGE_00182 2.2e-66 carB 6.3.5.5 C carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HEFJEAGE_00183 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HEFJEAGE_00184 4.3e-33 copZ P Heavy-metal-associated domain
HEFJEAGE_00185 5.4e-46 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
HEFJEAGE_00186 1.7e-111 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HEFJEAGE_00187 1.8e-240 brnQ U Component of the transport system for branched-chain amino acids
HEFJEAGE_00188 8.1e-125 alkD L DNA alkylation repair enzyme
HEFJEAGE_00189 9.6e-94 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
HEFJEAGE_00190 5.3e-105 T Gaf domain
HEFJEAGE_00191 2.7e-31 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_00193 1.2e-26 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HEFJEAGE_00194 3.8e-52 ypaA S membrane
HEFJEAGE_00195 1.3e-84 K AsnC family
HEFJEAGE_00196 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEFJEAGE_00197 6.1e-52 mtlR K transcriptional antiterminator
HEFJEAGE_00199 1.1e-32 mtlD 1.1.1.17 G mannitol metabolic process
HEFJEAGE_00200 5.7e-36 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HEFJEAGE_00201 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HEFJEAGE_00202 1.2e-161 mleP3 S Membrane transport protein
HEFJEAGE_00203 2.2e-309 ybiT S ABC transporter, ATP-binding protein
HEFJEAGE_00204 1.4e-100 kgtP EGP Sugar (and other) transporter
HEFJEAGE_00205 6.1e-49 kgtP EGP Sugar (and other) transporter
HEFJEAGE_00207 2.6e-56
HEFJEAGE_00208 3.3e-217 mdtG EGP Major facilitator Superfamily
HEFJEAGE_00209 5.5e-119 ybhL S Belongs to the BI1 family
HEFJEAGE_00210 1.7e-142 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEFJEAGE_00211 2.2e-281 pipD E Dipeptidase
HEFJEAGE_00212 7.8e-210 pepA E M42 glutamyl aminopeptidase
HEFJEAGE_00213 2e-100 S ABC-type cobalt transport system, permease component
HEFJEAGE_00215 3.7e-111 udk 2.7.1.48 F Zeta toxin
HEFJEAGE_00216 3.9e-119 udk 2.7.1.48 F Zeta toxin
HEFJEAGE_00217 5.9e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEFJEAGE_00218 1.6e-149 glnH ET ABC transporter substrate-binding protein
HEFJEAGE_00219 3.2e-110 gluC P ABC transporter permease
HEFJEAGE_00220 5.7e-110 glnP P ABC transporter permease
HEFJEAGE_00221 2.2e-148 glnH ET Bacterial periplasmic substrate-binding proteins
HEFJEAGE_00222 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HEFJEAGE_00223 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEFJEAGE_00224 3.3e-269 S Uncharacterized protein conserved in bacteria (DUF2252)
HEFJEAGE_00225 5.6e-10 S Protein of unknown function (DUF2974)
HEFJEAGE_00226 4.8e-38
HEFJEAGE_00227 5.9e-88
HEFJEAGE_00228 1.4e-113 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEFJEAGE_00229 4.7e-39 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEFJEAGE_00230 1.3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HEFJEAGE_00231 5.5e-124 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEFJEAGE_00232 1.2e-174 rihB 3.2.2.1 F Nucleoside
HEFJEAGE_00233 2.6e-39 gntR K UbiC transcription regulator-associated domain protein
HEFJEAGE_00234 9.5e-86 gntR K UbiC transcription regulator-associated domain protein
HEFJEAGE_00235 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HEFJEAGE_00238 2.4e-17 3.4.22.70 M Sortase family
HEFJEAGE_00239 2.1e-249 yhdP S Transporter associated domain
HEFJEAGE_00240 9.8e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HEFJEAGE_00241 8.4e-227 potE E amino acid
HEFJEAGE_00242 1.2e-123 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HEFJEAGE_00243 1.3e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
HEFJEAGE_00244 9.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEFJEAGE_00246 6.8e-182 pfoS S Phosphotransferase system, EIIC
HEFJEAGE_00247 1.2e-233 pyrP F Permease
HEFJEAGE_00248 1.1e-228 ynbB 4.4.1.1 P aluminum resistance
HEFJEAGE_00249 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HEFJEAGE_00251 7.1e-122 E Amino acid permease
HEFJEAGE_00252 1.4e-133 E Amino acid permease
HEFJEAGE_00253 1.4e-24
HEFJEAGE_00254 1e-212 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEFJEAGE_00255 3.3e-51 gtcA S Teichoic acid glycosylation protein
HEFJEAGE_00256 1.3e-78 fld C Flavodoxin
HEFJEAGE_00257 3.6e-162 map 3.4.11.18 E Methionine Aminopeptidase
HEFJEAGE_00258 2.6e-166 yihY S Belongs to the UPF0761 family
HEFJEAGE_00259 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEFJEAGE_00260 7.4e-19
HEFJEAGE_00261 7.6e-180 D Alpha beta
HEFJEAGE_00262 1.1e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEFJEAGE_00263 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
HEFJEAGE_00264 4.5e-85
HEFJEAGE_00265 1.7e-73
HEFJEAGE_00266 1.2e-157 hlyX S Transporter associated domain
HEFJEAGE_00267 1.4e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEFJEAGE_00268 5.4e-19
HEFJEAGE_00269 1.1e-204 mco Q Multicopper oxidase
HEFJEAGE_00270 3.3e-73 mco Q Multicopper oxidase
HEFJEAGE_00271 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
HEFJEAGE_00272 0.0 clpE O Belongs to the ClpA ClpB family
HEFJEAGE_00273 5.8e-10
HEFJEAGE_00274 1.2e-39 ptsH G phosphocarrier protein HPR
HEFJEAGE_00275 2.1e-302 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEFJEAGE_00276 5e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEFJEAGE_00277 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HEFJEAGE_00278 4.4e-163 coiA 3.6.4.12 S Competence protein
HEFJEAGE_00279 5.9e-112 yjbH Q Thioredoxin
HEFJEAGE_00280 3.3e-109 yjbK S CYTH
HEFJEAGE_00281 3.1e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HEFJEAGE_00282 3.9e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEFJEAGE_00283 8.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEFJEAGE_00284 2.8e-22
HEFJEAGE_00285 2.7e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEFJEAGE_00286 2.7e-196 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HEFJEAGE_00287 3.5e-64 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HEFJEAGE_00288 2.1e-181 yubA S AI-2E family transporter
HEFJEAGE_00289 8.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEFJEAGE_00290 1.9e-68 WQ51_03320 S Protein of unknown function (DUF1149)
HEFJEAGE_00291 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HEFJEAGE_00292 2.1e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HEFJEAGE_00293 3.3e-236 S Peptidase M16
HEFJEAGE_00294 2.6e-132 IQ Enoyl-(Acyl carrier protein) reductase
HEFJEAGE_00295 3.9e-106 ymfM S Helix-turn-helix domain
HEFJEAGE_00296 2.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEFJEAGE_00297 4.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEFJEAGE_00298 5.1e-221 rny S Endoribonuclease that initiates mRNA decay
HEFJEAGE_00299 9.9e-214 tagO 2.7.8.33, 2.7.8.35 M transferase
HEFJEAGE_00300 4.7e-117 yvyE 3.4.13.9 S YigZ family
HEFJEAGE_00301 1.4e-245 comFA L Helicase C-terminal domain protein
HEFJEAGE_00302 1.3e-120 comFC S Competence protein
HEFJEAGE_00303 1.6e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEFJEAGE_00304 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEFJEAGE_00305 5.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEFJEAGE_00306 9.1e-31
HEFJEAGE_00307 1e-173 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEFJEAGE_00308 1.5e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEFJEAGE_00309 5.5e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HEFJEAGE_00310 9.2e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEFJEAGE_00311 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEFJEAGE_00312 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEFJEAGE_00313 3.7e-91 S Short repeat of unknown function (DUF308)
HEFJEAGE_00314 4.4e-146 E D-aminopeptidase
HEFJEAGE_00315 1.5e-80 dmpA 3.4.11.19 EQ Peptidase family S58
HEFJEAGE_00316 9e-164 rapZ S Displays ATPase and GTPase activities
HEFJEAGE_00317 1.4e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HEFJEAGE_00318 1.5e-169 whiA K May be required for sporulation
HEFJEAGE_00319 5.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEFJEAGE_00320 9.6e-283
HEFJEAGE_00321 2.2e-28 ABC-SBP S ABC transporter substrate binding protein
HEFJEAGE_00322 5.1e-53 ABC-SBP S ABC transporter
HEFJEAGE_00323 8.2e-10 ABC-SBP S ABC transporter
HEFJEAGE_00324 3.9e-30 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HEFJEAGE_00325 4.4e-102 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HEFJEAGE_00326 5.3e-136 XK27_08845 S ABC transporter, ATP-binding protein
HEFJEAGE_00328 5.2e-212 cggR K Putative sugar-binding domain
HEFJEAGE_00329 2.2e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEFJEAGE_00330 3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HEFJEAGE_00331 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEFJEAGE_00332 4.9e-26 3.2.2.20 K acetyltransferase
HEFJEAGE_00333 2e-45 3.2.2.20 K acetyltransferase
HEFJEAGE_00334 1.6e-105
HEFJEAGE_00335 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
HEFJEAGE_00336 6.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEFJEAGE_00337 2.8e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HEFJEAGE_00338 4.2e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HEFJEAGE_00339 1.2e-97 dnaQ 2.7.7.7 L DNA polymerase III
HEFJEAGE_00340 1.9e-161 murB 1.3.1.98 M Cell wall formation
HEFJEAGE_00341 1.4e-203 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEFJEAGE_00342 1.1e-144 potB P ABC transporter permease
HEFJEAGE_00343 6.6e-129 potC P ABC transporter permease
HEFJEAGE_00344 5.3e-206 potD P ABC transporter
HEFJEAGE_00345 3.9e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEFJEAGE_00346 2.7e-166 ybbR S YbbR-like protein
HEFJEAGE_00347 3.4e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEFJEAGE_00348 8.9e-150 S hydrolase
HEFJEAGE_00349 1.1e-56 V peptidase activity
HEFJEAGE_00350 1.4e-77 atkY K Copper transport repressor CopY TcrY
HEFJEAGE_00351 2.5e-54 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HEFJEAGE_00352 0.0 copA 3.6.3.54 P P-type ATPase
HEFJEAGE_00353 2.5e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFJEAGE_00354 5e-60 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFJEAGE_00355 3.8e-73
HEFJEAGE_00356 2.8e-148 T diguanylate cyclase activity
HEFJEAGE_00357 1.3e-179 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_00358 7.2e-77 T Diguanylate cyclase, GGDEF domain
HEFJEAGE_00359 1.3e-125 T Diguanylate cyclase, GGDEF domain
HEFJEAGE_00360 1.5e-25
HEFJEAGE_00361 3.1e-66
HEFJEAGE_00362 2.4e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEFJEAGE_00363 7.2e-68 GM epimerase
HEFJEAGE_00364 0.0 E Amino acid permease
HEFJEAGE_00365 6.5e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEFJEAGE_00366 2e-157 rssA S Phospholipase, patatin family
HEFJEAGE_00367 1.2e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
HEFJEAGE_00368 2e-94 S VanZ like family
HEFJEAGE_00369 1.4e-130 yebC K Transcriptional regulatory protein
HEFJEAGE_00370 4.4e-180 comGA NU Type II IV secretion system protein
HEFJEAGE_00371 2.9e-158 comGB NU type II secretion system
HEFJEAGE_00372 1.4e-50 comGC U competence protein ComGC
HEFJEAGE_00373 2.3e-75
HEFJEAGE_00375 1.9e-11 comGF U Putative Competence protein ComGF
HEFJEAGE_00376 2.8e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
HEFJEAGE_00377 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEFJEAGE_00380 6.1e-134 K Transcriptional regulatory protein, C terminal
HEFJEAGE_00381 4.5e-275 T PhoQ Sensor
HEFJEAGE_00382 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEFJEAGE_00383 3.6e-114 vanZ V VanZ like family
HEFJEAGE_00384 6.2e-257 pgi 5.3.1.9 G Belongs to the GPI family
HEFJEAGE_00385 6.1e-85 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00386 2.3e-176 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00389 7.6e-191 ampC V Beta-lactamase
HEFJEAGE_00390 4.3e-34
HEFJEAGE_00391 3.2e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HEFJEAGE_00392 1.4e-112 tdk 2.7.1.21 F thymidine kinase
HEFJEAGE_00393 7.9e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEFJEAGE_00394 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEFJEAGE_00395 9.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEFJEAGE_00396 3.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEFJEAGE_00397 4.2e-127 atpB C it plays a direct role in the translocation of protons across the membrane
HEFJEAGE_00398 7e-28 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEFJEAGE_00399 4.2e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEFJEAGE_00400 1.8e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEFJEAGE_00401 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEFJEAGE_00402 2.4e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEFJEAGE_00403 1.9e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEFJEAGE_00404 1.6e-73 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HEFJEAGE_00405 5.1e-32 ywzB S Protein of unknown function (DUF1146)
HEFJEAGE_00406 6.1e-177 mbl D Cell shape determining protein MreB Mrl
HEFJEAGE_00407 1.7e-47 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HEFJEAGE_00408 1.7e-34 S Protein of unknown function (DUF2969)
HEFJEAGE_00409 1.6e-219 rodA D Belongs to the SEDS family
HEFJEAGE_00410 2.3e-78 usp6 T universal stress protein
HEFJEAGE_00411 1.3e-42
HEFJEAGE_00412 3.6e-241 rarA L recombination factor protein RarA
HEFJEAGE_00413 1.1e-80 yueI S Protein of unknown function (DUF1694)
HEFJEAGE_00414 1.2e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEFJEAGE_00415 9.9e-300 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEFJEAGE_00416 9.2e-217 iscS2 2.8.1.7 E Aminotransferase class V
HEFJEAGE_00417 4.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEFJEAGE_00418 2.3e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEFJEAGE_00419 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEFJEAGE_00420 1.2e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HEFJEAGE_00421 6.8e-127 S Haloacid dehalogenase-like hydrolase
HEFJEAGE_00422 1.2e-114 radC L DNA repair protein
HEFJEAGE_00423 2.6e-175 mreB D cell shape determining protein MreB
HEFJEAGE_00424 2.8e-138 mreC M Involved in formation and maintenance of cell shape
HEFJEAGE_00425 9.3e-95 mreD
HEFJEAGE_00427 5.7e-55 S Protein of unknown function (DUF3397)
HEFJEAGE_00428 4.1e-77 mraZ K Belongs to the MraZ family
HEFJEAGE_00429 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEFJEAGE_00430 4.8e-55 ftsL D Cell division protein FtsL
HEFJEAGE_00431 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HEFJEAGE_00432 4.5e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEFJEAGE_00433 5.6e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEFJEAGE_00434 1.2e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEFJEAGE_00435 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEFJEAGE_00436 6e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEFJEAGE_00437 1.4e-219 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEFJEAGE_00438 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEFJEAGE_00439 7.6e-46 yggT S YGGT family
HEFJEAGE_00440 7.7e-146 ylmH S S4 domain protein
HEFJEAGE_00441 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEFJEAGE_00442 1.5e-32 cspA K 'Cold-shock' DNA-binding domain
HEFJEAGE_00443 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HEFJEAGE_00444 5.4e-19
HEFJEAGE_00445 3.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEFJEAGE_00446 2.8e-213 iscS 2.8.1.7 E Aminotransferase class V
HEFJEAGE_00447 3.2e-56 XK27_04120 S Putative amino acid metabolism
HEFJEAGE_00448 2.1e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEFJEAGE_00449 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HEFJEAGE_00450 3e-103 S Repeat protein
HEFJEAGE_00451 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEFJEAGE_00452 5.1e-251 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HEFJEAGE_00453 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEFJEAGE_00454 2.7e-35 ykzG S Belongs to the UPF0356 family
HEFJEAGE_00455 4.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEFJEAGE_00456 0.0 typA T GTP-binding protein TypA
HEFJEAGE_00457 4.2e-212 ftsW D Belongs to the SEDS family
HEFJEAGE_00458 1.1e-53 ylbG S UPF0298 protein
HEFJEAGE_00459 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HEFJEAGE_00460 9.8e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEFJEAGE_00461 7.8e-191 ylbL T Belongs to the peptidase S16 family
HEFJEAGE_00462 6.4e-70 comEA L Competence protein ComEA
HEFJEAGE_00463 0.0 comEC S Competence protein ComEC
HEFJEAGE_00464 1.6e-180 holA 2.7.7.7 L DNA polymerase III delta subunit
HEFJEAGE_00465 1.6e-33 rpsT J Binds directly to 16S ribosomal RNA
HEFJEAGE_00466 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEFJEAGE_00467 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEFJEAGE_00468 1.3e-148
HEFJEAGE_00469 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEFJEAGE_00470 3.5e-212 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEFJEAGE_00471 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEFJEAGE_00472 6.3e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HEFJEAGE_00473 7.4e-257 I Protein of unknown function (DUF2974)
HEFJEAGE_00475 6.2e-125 pnb C nitroreductase
HEFJEAGE_00477 0.0 E ABC transporter, substratebinding protein
HEFJEAGE_00478 5.4e-65
HEFJEAGE_00479 1.7e-24 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HEFJEAGE_00480 1.9e-89 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HEFJEAGE_00481 1.8e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEFJEAGE_00482 1.3e-87 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEFJEAGE_00483 1.9e-38 aha1 P E1-E2 ATPase
HEFJEAGE_00484 0.0 aha1 P E1-E2 ATPase
HEFJEAGE_00485 3.2e-121 metQ2 P Belongs to the nlpA lipoprotein family
HEFJEAGE_00486 3.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEFJEAGE_00487 5e-112 metI P ABC transporter permease
HEFJEAGE_00488 8.4e-265 frdC 1.3.5.4 C FAD binding domain
HEFJEAGE_00489 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HEFJEAGE_00490 4.7e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEFJEAGE_00491 5.7e-72 L DDE superfamily endonuclease
HEFJEAGE_00492 2.8e-14 L Transposase
HEFJEAGE_00493 1.1e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HEFJEAGE_00494 3.7e-130 pepO 3.4.24.71 O Peptidase family M13
HEFJEAGE_00495 1.5e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HEFJEAGE_00496 2.3e-57
HEFJEAGE_00497 1.6e-70 L DDE superfamily endonuclease
HEFJEAGE_00498 2.6e-135 L DDE superfamily endonuclease
HEFJEAGE_00499 4.5e-64 S Domain of unknown function DUF1828
HEFJEAGE_00500 8.8e-218 EGP Major facilitator Superfamily
HEFJEAGE_00501 2.8e-257 glnA 6.3.1.2 E glutamine synthetase
HEFJEAGE_00502 1.4e-170 ynbB 4.4.1.1 P aluminum resistance
HEFJEAGE_00503 5.2e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEFJEAGE_00504 2.6e-70 yqhL P Rhodanese-like protein
HEFJEAGE_00505 2.1e-32 yqgQ S Bacterial protein of unknown function (DUF910)
HEFJEAGE_00506 2.6e-115 gluP 3.4.21.105 S Rhomboid family
HEFJEAGE_00507 2.1e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEFJEAGE_00508 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEFJEAGE_00509 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HEFJEAGE_00510 0.0 S membrane
HEFJEAGE_00511 2e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEFJEAGE_00512 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEFJEAGE_00513 2.1e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEFJEAGE_00514 2e-61 yodB K Transcriptional regulator, HxlR family
HEFJEAGE_00515 1.2e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEFJEAGE_00516 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HEFJEAGE_00517 4.4e-156 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEFJEAGE_00518 8.6e-290 arlS 2.7.13.3 T Histidine kinase
HEFJEAGE_00519 2.9e-128 K response regulator
HEFJEAGE_00520 8.4e-102 yceD S Uncharacterized ACR, COG1399
HEFJEAGE_00521 4.3e-214 ylbM S Belongs to the UPF0348 family
HEFJEAGE_00522 1.2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEFJEAGE_00523 1.9e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HEFJEAGE_00524 2.9e-119 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEFJEAGE_00525 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
HEFJEAGE_00526 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEFJEAGE_00527 1.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HEFJEAGE_00528 2.6e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEFJEAGE_00529 2.9e-298 L Putative transposase DNA-binding domain
HEFJEAGE_00530 5.4e-113 guaB2 L Resolvase, N terminal domain
HEFJEAGE_00531 4.5e-274 S Archaea bacterial proteins of unknown function
HEFJEAGE_00532 2.3e-32
HEFJEAGE_00533 1.5e-43
HEFJEAGE_00534 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEFJEAGE_00535 1.3e-168 dnaI L Primosomal protein DnaI
HEFJEAGE_00536 3.4e-247 dnaB L Replication initiation and membrane attachment
HEFJEAGE_00537 7.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEFJEAGE_00538 1.9e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEFJEAGE_00539 9e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEFJEAGE_00540 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEFJEAGE_00541 3.5e-39 EGP Major facilitator Superfamily
HEFJEAGE_00542 2.7e-112 EGP Major facilitator Superfamily
HEFJEAGE_00543 1.1e-42 EGP Major facilitator Superfamily
HEFJEAGE_00544 1.2e-59 ypmB S Protein conserved in bacteria
HEFJEAGE_00545 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HEFJEAGE_00546 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HEFJEAGE_00547 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HEFJEAGE_00548 1.8e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HEFJEAGE_00549 1.7e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HEFJEAGE_00550 3.5e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HEFJEAGE_00551 1.3e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEFJEAGE_00552 1.4e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
HEFJEAGE_00553 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEFJEAGE_00554 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEFJEAGE_00555 1.3e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEFJEAGE_00556 5.1e-46 yfiC V ABC transporter
HEFJEAGE_00557 4.7e-115 yfiC V ABC transporter
HEFJEAGE_00558 2.8e-52 V abc transporter atp-binding protein
HEFJEAGE_00559 5.5e-43 lmrA V ABC transporter, ATP-binding protein
HEFJEAGE_00560 4e-34 lmrA V (ABC) transporter
HEFJEAGE_00561 1.2e-14 K Winged helix DNA-binding domain
HEFJEAGE_00562 5e-153 supH G Sucrose-6F-phosphate phosphohydrolase
HEFJEAGE_00563 3.4e-103
HEFJEAGE_00564 8.5e-190 2.7.7.65 T diguanylate cyclase
HEFJEAGE_00565 2.5e-112 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_00566 5.7e-74 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_00567 1.1e-70 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_00568 8.4e-103 2.7.7.65 T phosphorelay sensor kinase activity
HEFJEAGE_00569 5.6e-133 cbiQ P Cobalt transport protein
HEFJEAGE_00570 5.5e-147 P ABC transporter
HEFJEAGE_00571 4.6e-140 cbiO2 P ABC transporter
HEFJEAGE_00572 3.1e-93 S C4-dicarboxylate anaerobic carrier
HEFJEAGE_00573 2.5e-103 I NUDIX domain
HEFJEAGE_00574 9.1e-192 S Glycosyl hydrolases family 18
HEFJEAGE_00575 7e-121 3.6.1.13 L NUDIX domain
HEFJEAGE_00577 3.2e-65 lsa S ABC transporter
HEFJEAGE_00578 8.4e-16 lsa S ABC transporter
HEFJEAGE_00579 5.1e-33 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HEFJEAGE_00580 2.4e-21 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HEFJEAGE_00581 3.2e-303 phoR 2.7.13.3 T Histidine kinase
HEFJEAGE_00582 1.4e-124 T Transcriptional regulatory protein, C terminal
HEFJEAGE_00583 6.4e-111 phoU P Plays a role in the regulation of phosphate uptake
HEFJEAGE_00584 3.2e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEFJEAGE_00585 8.1e-157 pstA P Phosphate transport system permease protein PstA
HEFJEAGE_00586 4.3e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HEFJEAGE_00587 1.7e-154 pstS P Phosphate
HEFJEAGE_00590 2.7e-65 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_00591 1.7e-50 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_00592 2.6e-36
HEFJEAGE_00593 1.9e-13 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00594 3.9e-108 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00595 1.8e-54 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00599 8.4e-85 L DDE superfamily endonuclease
HEFJEAGE_00600 3.7e-26 lysR7 K LysR substrate binding domain
HEFJEAGE_00601 1.4e-118 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HEFJEAGE_00602 9.1e-167 L Belongs to the 'phage' integrase family
HEFJEAGE_00603 6.9e-71 hsdS_1 3.1.21.3 V Type I restriction
HEFJEAGE_00604 1.9e-268 hsdM 2.1.1.72 V type I restriction-modification system
HEFJEAGE_00605 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HEFJEAGE_00606 5.5e-80 GM NmrA-like family
HEFJEAGE_00607 5.1e-85 T Diguanylate cyclase, GGDEF domain
HEFJEAGE_00608 3.2e-55 S Sel1-like repeats.
HEFJEAGE_00609 2.2e-155 S Uncharacterized protein conserved in bacteria (DUF2325)
HEFJEAGE_00610 6.4e-210 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HEFJEAGE_00611 1.4e-198 xerS L Belongs to the 'phage' integrase family
HEFJEAGE_00612 5.5e-17 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEFJEAGE_00613 6.7e-24 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEFJEAGE_00614 1.3e-60 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEFJEAGE_00615 7e-26 C Nitroreductase family
HEFJEAGE_00616 8.1e-54 C Nitroreductase family
HEFJEAGE_00617 4.7e-13 XK27_06780 V ABC transporter permease
HEFJEAGE_00618 1.9e-115 3.1.3.73 G phosphoglycerate mutase
HEFJEAGE_00619 4.8e-87 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEFJEAGE_00620 1.1e-83 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEFJEAGE_00621 1.3e-85 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFJEAGE_00622 2.1e-120 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFJEAGE_00623 4.9e-165 EG EamA-like transporter family
HEFJEAGE_00624 3.6e-183
HEFJEAGE_00625 6.3e-157 degV S EDD domain protein, DegV family
HEFJEAGE_00626 1.1e-306 FbpA K Fibronectin-binding protein
HEFJEAGE_00627 2.9e-246 XK27_08635 S UPF0210 protein
HEFJEAGE_00628 4.8e-42 gcvR T Belongs to the UPF0237 family
HEFJEAGE_00629 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HEFJEAGE_00630 3.3e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEFJEAGE_00631 8.7e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEFJEAGE_00632 9.3e-72 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEFJEAGE_00633 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HEFJEAGE_00634 5.4e-59
HEFJEAGE_00635 5.2e-68 XK27_01810 S Calcineurin-like phosphoesterase
HEFJEAGE_00636 3.6e-100 XK27_01810 S Calcineurin-like phosphoesterase
HEFJEAGE_00637 8.7e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HEFJEAGE_00638 1e-57 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEFJEAGE_00639 2.1e-105 ypsA S Belongs to the UPF0398 family
HEFJEAGE_00640 2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEFJEAGE_00641 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HEFJEAGE_00642 0.0 dap2 3.4.19.1 E Prolyl oligopeptidase family
HEFJEAGE_00643 2.4e-189 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFJEAGE_00644 8.6e-59 I acetylesterase activity
HEFJEAGE_00645 3e-53 I Psort location Cytoplasmic, score
HEFJEAGE_00646 6.8e-150 S Sucrose-6F-phosphate phosphohydrolase
HEFJEAGE_00647 5.5e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEFJEAGE_00648 9.7e-115 dnaD L DnaD domain protein
HEFJEAGE_00649 3.1e-32 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HEFJEAGE_00650 8.5e-116 K Bacterial regulatory proteins, tetR family
HEFJEAGE_00651 0.0 yhcA V ABC transporter, ATP-binding protein
HEFJEAGE_00652 3.8e-66 S Iron-sulphur cluster biosynthesis
HEFJEAGE_00653 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEFJEAGE_00654 2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEFJEAGE_00655 1.2e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
HEFJEAGE_00656 2.2e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEFJEAGE_00658 7.4e-49
HEFJEAGE_00659 1.1e-225 ywhK S Membrane
HEFJEAGE_00660 3.7e-66 L An automated process has identified a potential problem with this gene model
HEFJEAGE_00661 7.3e-86 ykuL S (CBS) domain
HEFJEAGE_00662 0.0 cadA P P-type ATPase
HEFJEAGE_00663 3.2e-201 napA P Sodium/hydrogen exchanger family
HEFJEAGE_00664 2.4e-121 S CAAX protease self-immunity
HEFJEAGE_00665 1.2e-200 S DUF218 domain
HEFJEAGE_00666 6.1e-194 tcsA S ABC transporter substrate-binding protein PnrA-like
HEFJEAGE_00668 4.4e-65 S Psort location Cytoplasmic, score
HEFJEAGE_00669 4e-187 KLT Protein tyrosine kinase
HEFJEAGE_00670 1e-70 S Domain of unknown function (DUF4352)
HEFJEAGE_00671 2.2e-196 tcsA S ABC transporter substrate-binding protein PnrA-like
HEFJEAGE_00672 2.3e-193 tcsA S ABC transporter substrate-binding protein PnrA-like
HEFJEAGE_00673 2.1e-285 xylG 3.6.3.17 S ABC transporter
HEFJEAGE_00674 1e-204 yufP S Belongs to the binding-protein-dependent transport system permease family
HEFJEAGE_00675 1.3e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
HEFJEAGE_00676 5.1e-62 EGP Major facilitator Superfamily
HEFJEAGE_00677 5.5e-98 EGP Major facilitator Superfamily
HEFJEAGE_00678 3.6e-154 yeaE S Aldo/keto reductase family
HEFJEAGE_00679 1.5e-124 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEFJEAGE_00680 1.9e-139 L COG2963 Transposase and inactivated derivatives
HEFJEAGE_00682 3.3e-62 V ATPases associated with a variety of cellular activities
HEFJEAGE_00683 8.2e-32
HEFJEAGE_00684 5.8e-123 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HEFJEAGE_00685 2.2e-128 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HEFJEAGE_00686 2.2e-268 glnP P ABC transporter
HEFJEAGE_00687 5.5e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEFJEAGE_00688 3.7e-230 pbuG S permease
HEFJEAGE_00689 4.1e-281 clcA P chloride
HEFJEAGE_00690 1e-54 XK27_08850 S Aminoacyl-tRNA editing domain
HEFJEAGE_00691 1.4e-48 1.3.5.4 C FAD dependent oxidoreductase
HEFJEAGE_00692 6.8e-113 K Helix-turn-helix domain
HEFJEAGE_00693 5.3e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HEFJEAGE_00694 3.4e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEFJEAGE_00695 1.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEFJEAGE_00696 5.2e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEFJEAGE_00697 1.1e-217 ecsB U ABC transporter
HEFJEAGE_00698 1.8e-136 ecsA V ABC transporter, ATP-binding protein
HEFJEAGE_00699 2.2e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HEFJEAGE_00700 1.8e-54
HEFJEAGE_00701 5.2e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEFJEAGE_00702 1.2e-132 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEFJEAGE_00703 2.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEFJEAGE_00704 1.1e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEFJEAGE_00705 9.8e-52 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEFJEAGE_00706 1.1e-67 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F shikimate kinase activity
HEFJEAGE_00707 1.1e-178 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEFJEAGE_00708 0.0 L AAA domain
HEFJEAGE_00709 3.9e-226 yhaO L Ser Thr phosphatase family protein
HEFJEAGE_00710 8.1e-55 yheA S Belongs to the UPF0342 family
HEFJEAGE_00711 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEFJEAGE_00712 5.3e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEFJEAGE_00713 3.9e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HEFJEAGE_00714 4.9e-96 M ErfK YbiS YcfS YnhG
HEFJEAGE_00715 1e-57 3.4.22.70 M Sortase family
HEFJEAGE_00716 2.7e-59
HEFJEAGE_00717 1.2e-47 L Putative transposase DNA-binding domain
HEFJEAGE_00719 3e-223 M ErfK YbiS YcfS YnhG
HEFJEAGE_00720 4.7e-157 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEFJEAGE_00721 2.1e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEFJEAGE_00723 6.2e-88 1.2.3.3, 3.7.1.22 EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
HEFJEAGE_00724 4.5e-39 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HEFJEAGE_00725 1.1e-147 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HEFJEAGE_00726 1.6e-149
HEFJEAGE_00727 7.6e-67 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HEFJEAGE_00728 1.7e-56 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HEFJEAGE_00729 4.5e-82 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HEFJEAGE_00730 1.3e-41 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HEFJEAGE_00731 3.1e-119 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HEFJEAGE_00732 1.3e-293 ytgP S Polysaccharide biosynthesis protein
HEFJEAGE_00733 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEFJEAGE_00734 7.9e-19 L Transposase and inactivated derivatives, IS30 family
HEFJEAGE_00735 2.2e-196 S Acyltransferase family
HEFJEAGE_00736 9.3e-120 G Peptidase_C39 like family
HEFJEAGE_00738 4.2e-89 M NlpC/P60 family
HEFJEAGE_00739 2.2e-09 M NlpC/P60 family
HEFJEAGE_00740 9.2e-80 S VanZ like family
HEFJEAGE_00741 9.4e-74 mesH S Teichoic acid glycosylation protein
HEFJEAGE_00742 2.2e-128 S VanZ like family
HEFJEAGE_00743 2.6e-58 sidC L DNA recombination
HEFJEAGE_00744 6.9e-84 sidC L DNA recombination
HEFJEAGE_00745 1.3e-10 sidC L DNA recombination
HEFJEAGE_00746 0.0 3.1.4.46, 3.2.1.99 GH43 N domain, Protein
HEFJEAGE_00748 2.5e-39
HEFJEAGE_00749 3.4e-134 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEFJEAGE_00750 2e-123 pgm3 G Phosphoglycerate mutase family
HEFJEAGE_00751 7.6e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HEFJEAGE_00752 0.0 helD 3.6.4.12 L DNA helicase
HEFJEAGE_00753 5e-41 glnQ 3.6.3.21 E ABC transporter
HEFJEAGE_00754 1.6e-48 aatB ET ABC transporter substrate-binding protein
HEFJEAGE_00755 1.8e-84 aatB ET ABC transporter substrate-binding protein
HEFJEAGE_00756 1e-11 liaI S membrane
HEFJEAGE_00757 4.4e-74 XK27_02470 K LytTr DNA-binding domain
HEFJEAGE_00758 5.7e-103 E GDSL-like Lipase/Acylhydrolase
HEFJEAGE_00759 1e-170 coaA 2.7.1.33 F Pantothenic acid kinase
HEFJEAGE_00760 1.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEFJEAGE_00761 1.6e-76 ymfM S Helix-turn-helix domain
HEFJEAGE_00762 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HEFJEAGE_00763 1.2e-197
HEFJEAGE_00764 5.2e-39 L COG2826 Transposase and inactivated derivatives, IS30 family
HEFJEAGE_00765 1.4e-14 L the current gene model (or a revised gene model) may contain a frame shift
HEFJEAGE_00766 1.8e-108 L COG2826 Transposase and inactivated derivatives, IS30 family
HEFJEAGE_00767 3.3e-289 V ABC transporter transmembrane region
HEFJEAGE_00768 6e-09 S PAS domain
HEFJEAGE_00769 1.4e-38 GK ROK family
HEFJEAGE_00770 1.2e-35 GK ROK family
HEFJEAGE_00772 1.6e-157 dkg S reductase
HEFJEAGE_00773 3e-124 endA F DNA RNA non-specific endonuclease
HEFJEAGE_00774 1e-41 E dipeptidase activity
HEFJEAGE_00775 4.4e-106
HEFJEAGE_00776 5.4e-86 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HEFJEAGE_00777 4.6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HEFJEAGE_00778 2.9e-26 corA P CorA-like Mg2+ transporter protein
HEFJEAGE_00779 7.2e-111 corA P CorA-like Mg2+ transporter protein
HEFJEAGE_00780 1e-157 3.5.2.6 V Beta-lactamase enzyme family
HEFJEAGE_00781 1.6e-12
HEFJEAGE_00782 8.8e-99 yobS K Bacterial regulatory proteins, tetR family
HEFJEAGE_00783 0.0 ydgH S MMPL family
HEFJEAGE_00784 3.1e-174
HEFJEAGE_00785 5.5e-256 P Sodium:sulfate symporter transmembrane region
HEFJEAGE_00786 7.9e-263 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEFJEAGE_00788 1.1e-151
HEFJEAGE_00789 1.4e-34
HEFJEAGE_00790 4.4e-91 ymdB S Macro domain protein
HEFJEAGE_00791 2e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
HEFJEAGE_00792 7.2e-289 V ABC-type multidrug transport system, ATPase and permease components
HEFJEAGE_00793 0.0 KLT serine threonine protein kinase
HEFJEAGE_00794 2.6e-143 ptp2 3.1.3.48 T Tyrosine phosphatase family
HEFJEAGE_00795 2.4e-144 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEFJEAGE_00796 2.5e-27 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEFJEAGE_00797 1.4e-129 cobQ S glutamine amidotransferase
HEFJEAGE_00798 8.6e-37
HEFJEAGE_00799 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HEFJEAGE_00800 8.3e-08 T diguanylate cyclase
HEFJEAGE_00801 2.1e-72 5.99.1.2 T diguanylate cyclase
HEFJEAGE_00802 7e-25 5.99.1.2 T diguanylate cyclase
HEFJEAGE_00803 1.6e-66 brnQ U Component of the transport system for branched-chain amino acids
HEFJEAGE_00804 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HEFJEAGE_00805 1.6e-134 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEFJEAGE_00806 1.9e-61 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEFJEAGE_00807 9.4e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEFJEAGE_00808 1.9e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEFJEAGE_00809 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEFJEAGE_00810 2.8e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEFJEAGE_00811 3e-24 L DDE superfamily endonuclease
HEFJEAGE_00812 1.3e-50 L DDE superfamily endonuclease
HEFJEAGE_00813 1.1e-31 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEFJEAGE_00814 6.8e-44 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HEFJEAGE_00815 5.3e-159 yicL EG EamA-like transporter family
HEFJEAGE_00816 3.3e-138 puuD S peptidase C26
HEFJEAGE_00817 4.4e-149 S Sucrose-6F-phosphate phosphohydrolase
HEFJEAGE_00818 7.4e-166 S Alpha/beta hydrolase of unknown function (DUF915)
HEFJEAGE_00819 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEFJEAGE_00820 9.9e-146 ligA 2.7.7.7, 6.5.1.2 L EXOIII
HEFJEAGE_00821 1.1e-76 yyaQ S YjbR
HEFJEAGE_00822 6.7e-139 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HEFJEAGE_00823 7.8e-108 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
HEFJEAGE_00824 7.1e-130 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HEFJEAGE_00825 0.0 L Type III restriction enzyme, res subunit
HEFJEAGE_00826 1.2e-16 D Filamentation induced by cAMP protein fic
HEFJEAGE_00827 5.6e-14 S Fic/DOC family
HEFJEAGE_00828 5.4e-158 3.4.17.13 V LD-carboxypeptidase
HEFJEAGE_00829 4.5e-266 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HEFJEAGE_00830 1.3e-174
HEFJEAGE_00831 1.6e-137
HEFJEAGE_00832 3.4e-26
HEFJEAGE_00833 3.3e-112 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEFJEAGE_00834 2.1e-137 prsW S Involved in the degradation of specific anti-sigma factors
HEFJEAGE_00835 5e-74 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HEFJEAGE_00836 2.9e-35 metA 2.3.1.46 E L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HEFJEAGE_00837 1.2e-266 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HEFJEAGE_00838 9.4e-278 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEFJEAGE_00839 2.3e-170 E ABC transporter, ATP-binding protein
HEFJEAGE_00840 3e-78 K Transcriptional regulator
HEFJEAGE_00841 2.5e-84 1.6.5.2 GM NmrA-like family
HEFJEAGE_00842 3.1e-167 htpX O Peptidase family M48
HEFJEAGE_00843 1.3e-209 4.4.1.8 E Aminotransferase, class I
HEFJEAGE_00844 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HEFJEAGE_00845 4.3e-50 K GNAT family
HEFJEAGE_00846 9.5e-48
HEFJEAGE_00847 4.1e-18
HEFJEAGE_00848 3.5e-104 dedA 3.1.3.1 S SNARE associated Golgi protein
HEFJEAGE_00849 3.8e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
HEFJEAGE_00850 5.9e-46 K Transcriptional regulator
HEFJEAGE_00851 4e-47 GM epimerase
HEFJEAGE_00852 1.5e-19 S Protein of unknown function N-terminus (DUF3323)
HEFJEAGE_00855 0.0 yacH D Putative exonuclease SbcCD, C subunit
HEFJEAGE_00856 3.3e-53 yacH D Putative exonuclease SbcCD, C subunit
HEFJEAGE_00857 6.4e-90 yacH D Putative exonuclease SbcCD, C subunit
HEFJEAGE_00858 3.1e-57
HEFJEAGE_00859 1.3e-84 S Hydrolases of the alpha beta superfamily
HEFJEAGE_00860 1.4e-113 ylbE GM NAD(P)H-binding
HEFJEAGE_00861 5.9e-46 V (ABC) transporter
HEFJEAGE_00862 1.6e-120 V Psort location CytoplasmicMembrane, score 10.00
HEFJEAGE_00863 3.2e-29 V Psort location CytoplasmicMembrane, score 10.00
HEFJEAGE_00864 2.7e-76 V Psort location CytoplasmicMembrane, score
HEFJEAGE_00865 5e-176 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFJEAGE_00866 8.8e-78 K Transcriptional regulator, MarR family
HEFJEAGE_00867 3.8e-307 XK27_09600 V ABC transporter, ATP-binding protein
HEFJEAGE_00868 0.0 V ABC transporter transmembrane region
HEFJEAGE_00869 9.5e-52 P Rhodanese Homology Domain
HEFJEAGE_00870 3.8e-54 rnhA 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
HEFJEAGE_00871 3.7e-31 rnhA 3.1.26.4 L Resolvase, N-terminal
HEFJEAGE_00872 8.4e-63 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEFJEAGE_00874 1e-41 yjdJ S GCN5-related N-acetyl-transferase
HEFJEAGE_00875 2.8e-131 gph 3.1.3.18 S HAD-hyrolase-like
HEFJEAGE_00877 1.8e-60 C FAD binding domain
HEFJEAGE_00878 5e-27 K LytTr DNA-binding domain protein
HEFJEAGE_00879 7.5e-39 S SLAP domain
HEFJEAGE_00880 3.2e-106 ydaF J Acetyltransferase (GNAT) domain
HEFJEAGE_00882 9.5e-152 1.3.5.4 C FAD binding domain
HEFJEAGE_00883 5.4e-20 1.3.5.4 C FAD binding domain
HEFJEAGE_00884 2.1e-82 1.3.5.4 C FAD binding domain
HEFJEAGE_00885 4.1e-28 K Bacterial regulatory helix-turn-helix protein, lysR family
HEFJEAGE_00886 5.4e-13 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HEFJEAGE_00887 0.0 V FtsX-like permease family
HEFJEAGE_00888 2.1e-129 cysA V ABC transporter, ATP-binding protein
HEFJEAGE_00889 3.1e-71 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
HEFJEAGE_00890 2.7e-76
HEFJEAGE_00891 5.8e-77 S Psort location CytoplasmicMembrane, score
HEFJEAGE_00892 4.6e-104 cylB U ABC-2 type transporter
HEFJEAGE_00893 6.8e-138 cylA V ABC transporter
HEFJEAGE_00894 7.6e-58 XK27_03610 K Acetyltransferase (GNAT) domain
HEFJEAGE_00895 2.5e-106 L Integrase
HEFJEAGE_00896 2.7e-31 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HEFJEAGE_00897 2.2e-26 prpH 3.1.3.16 K 3.5.2 Transcription regulation
HEFJEAGE_00898 6.7e-60 prpH 3.1.3.16 K 3.5.2 Transcription regulation
HEFJEAGE_00899 0.0 carB 6.3.5.5 F Psort location Cytoplasmic, score 8.87
HEFJEAGE_00900 4.2e-33 V (ABC) transporter
HEFJEAGE_00901 3.1e-74 ybaJ Q Hypothetical methyltransferase
HEFJEAGE_00902 7.6e-34 ybaJ Q Methyltransferase domain
HEFJEAGE_00903 2.3e-152 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HEFJEAGE_00904 2.9e-73 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HEFJEAGE_00905 9.7e-118 WQ51_05710 S Mitochondrial biogenesis AIM24
HEFJEAGE_00906 3.1e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEFJEAGE_00907 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEFJEAGE_00908 2.1e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEFJEAGE_00909 2.1e-73 hsp O Belongs to the small heat shock protein (HSP20) family
HEFJEAGE_00910 1.6e-257 pepC 3.4.22.40 E Papain family cysteine protease
HEFJEAGE_00911 1.1e-255 pepC 3.4.22.40 E aminopeptidase
HEFJEAGE_00912 2.8e-179 oppF P Belongs to the ABC transporter superfamily
HEFJEAGE_00913 3.9e-198 oppD P Belongs to the ABC transporter superfamily
HEFJEAGE_00914 7.8e-183 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEFJEAGE_00915 2.6e-145 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEFJEAGE_00916 4.6e-302 oppA E ABC transporter
HEFJEAGE_00917 1.4e-105 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00918 4.3e-121 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00919 1.9e-30 oppA E transmembrane transport
HEFJEAGE_00920 3e-290 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00921 1.4e-245 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00922 4e-08 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00923 2.4e-121 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEFJEAGE_00924 1.6e-243 N Uncharacterized conserved protein (DUF2075)
HEFJEAGE_00925 2.9e-196 mmuP E amino acid
HEFJEAGE_00926 1.2e-232 amd 3.5.1.47 E Peptidase family M20/M25/M40
HEFJEAGE_00927 3e-62 E amino acid
HEFJEAGE_00928 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HEFJEAGE_00930 6.3e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEFJEAGE_00931 7e-07 S Acyltransferase family
HEFJEAGE_00932 2.7e-160 cjaA ET ABC transporter substrate-binding protein
HEFJEAGE_00933 1.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEFJEAGE_00934 2.2e-77 P ABC transporter permease
HEFJEAGE_00935 6e-112 papP P ABC transporter, permease protein
HEFJEAGE_00936 1.4e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
HEFJEAGE_00937 1.6e-94 L DDE superfamily endonuclease
HEFJEAGE_00938 1.5e-52 S Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HEFJEAGE_00939 0.0 XK27_08315 M Sulfatase
HEFJEAGE_00940 1.4e-107 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEFJEAGE_00941 1.7e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HEFJEAGE_00942 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEFJEAGE_00943 2e-132
HEFJEAGE_00944 1.1e-58 S Oxidoreductase
HEFJEAGE_00945 0.0 yjbQ P TrkA C-terminal domain protein
HEFJEAGE_00946 5.5e-276 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HEFJEAGE_00947 6.7e-170 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEFJEAGE_00948 4e-34 S Protein of unknown function (DUF2922)
HEFJEAGE_00949 1.3e-28
HEFJEAGE_00950 2.4e-85
HEFJEAGE_00951 1.7e-72
HEFJEAGE_00952 0.0 kup P Transport of potassium into the cell
HEFJEAGE_00953 0.0 pepO 3.4.24.71 O Peptidase family M13
HEFJEAGE_00954 5e-62 Z012_07300 O Glutaredoxin-related protein
HEFJEAGE_00955 2.5e-228 yttB EGP Major facilitator Superfamily
HEFJEAGE_00956 1.1e-36 XK27_04775 P Hemerythrin HHE cation binding domain protein
HEFJEAGE_00957 9.4e-33 S Iron-sulfur cluster assembly protein
HEFJEAGE_00958 1.4e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEFJEAGE_00959 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HEFJEAGE_00960 4.9e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
HEFJEAGE_00961 0.0 asnB 6.3.5.4 E Asparagine synthase
HEFJEAGE_00962 1.5e-274 S Calcineurin-like phosphoesterase
HEFJEAGE_00963 1.9e-83
HEFJEAGE_00964 1.3e-288 oppA E ABC transporter, substratebinding protein
HEFJEAGE_00965 4.9e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HEFJEAGE_00966 2.6e-125 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HEFJEAGE_00967 3.3e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HEFJEAGE_00968 2.3e-157 phnD P Phosphonate ABC transporter
HEFJEAGE_00969 2.5e-83 uspA T universal stress protein
HEFJEAGE_00970 1.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
HEFJEAGE_00971 1.9e-83 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEFJEAGE_00972 3e-89 ntd 2.4.2.6 F Nucleoside
HEFJEAGE_00973 1.5e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEFJEAGE_00974 0.0 G Belongs to the glycosyl hydrolase 31 family
HEFJEAGE_00975 1.3e-143 malG P ABC transporter permease
HEFJEAGE_00976 5.5e-101 malF P Binding-protein-dependent transport system inner membrane component
HEFJEAGE_00977 6.6e-53 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HEFJEAGE_00978 4.5e-30 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HEFJEAGE_00979 1.3e-170 I alpha/beta hydrolase fold
HEFJEAGE_00980 3.4e-130 yibF S overlaps another CDS with the same product name
HEFJEAGE_00981 5.8e-184 yibE S overlaps another CDS with the same product name
HEFJEAGE_00982 2.4e-11
HEFJEAGE_00983 7.8e-24
HEFJEAGE_00984 5.8e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HEFJEAGE_00985 2.5e-197 S Cysteine-rich secretory protein family
HEFJEAGE_00986 2.7e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HEFJEAGE_00987 1.2e-144
HEFJEAGE_00988 6.4e-125 luxT K Bacterial regulatory proteins, tetR family
HEFJEAGE_00989 4.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEFJEAGE_00990 2.8e-125 S Alpha/beta hydrolase family
HEFJEAGE_00991 2.5e-160 epsV 2.7.8.12 S glycosyl transferase family 2
HEFJEAGE_00992 1.1e-162 ypuA S Protein of unknown function (DUF1002)
HEFJEAGE_00993 5e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEFJEAGE_00994 5.1e-181 S Alpha/beta hydrolase of unknown function (DUF915)
HEFJEAGE_00995 5.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEFJEAGE_00996 1e-81
HEFJEAGE_00997 2.5e-132 cobB K SIR2 family
HEFJEAGE_00998 3.7e-66 yeaO S Protein of unknown function, DUF488
HEFJEAGE_00999 9.4e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HEFJEAGE_01000 1.1e-273 glnP P ABC transporter permease
HEFJEAGE_01001 3.5e-140 glnQ E ABC transporter, ATP-binding protein
HEFJEAGE_01003 1.5e-113 CBM50 M NlpC P60 family protein
HEFJEAGE_01004 4.5e-174 L HNH nucleases
HEFJEAGE_01005 2.8e-16
HEFJEAGE_01006 6.7e-182 ybiR P Citrate transporter
HEFJEAGE_01007 1.6e-94 lemA S LemA family
HEFJEAGE_01008 6.4e-149 htpX O Belongs to the peptidase M48B family
HEFJEAGE_01009 1.2e-152 mutR K Helix-turn-helix XRE-family like proteins
HEFJEAGE_01010 1.3e-221 S ATP diphosphatase activity
HEFJEAGE_01012 2.5e-138 S ABC-2 family transporter protein
HEFJEAGE_01013 1.6e-108 S ABC-2 family transporter protein
HEFJEAGE_01014 8.1e-171 natA1 S ABC transporter
HEFJEAGE_01015 1e-151 K helix_turn_helix, arabinose operon control protein
HEFJEAGE_01016 4.1e-270 emrY EGP Major facilitator Superfamily
HEFJEAGE_01017 4.6e-252 cbiO1 S ABC transporter, ATP-binding protein
HEFJEAGE_01018 3.2e-113 P Cobalt transport protein
HEFJEAGE_01019 3.9e-18 L transposase and inactivated derivatives, IS30 family
HEFJEAGE_01020 1.7e-36 L transposase and inactivated derivatives, IS30 family
HEFJEAGE_01021 2.7e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
HEFJEAGE_01026 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEFJEAGE_01027 7.2e-162 htrA 3.4.21.107 O serine protease
HEFJEAGE_01028 8.8e-150 vicX 3.1.26.11 S domain protein
HEFJEAGE_01029 1.5e-141 yycI S YycH protein
HEFJEAGE_01030 1.1e-241 yycH S YycH protein
HEFJEAGE_01031 0.0 vicK 2.7.13.3 T Histidine kinase
HEFJEAGE_01032 7.5e-132 K response regulator
HEFJEAGE_01034 8.5e-150 arbV 2.3.1.51 I Acyl-transferase
HEFJEAGE_01035 2.7e-154 arbx M Glycosyl transferase family 8
HEFJEAGE_01036 3e-95 arbY M Glycosyl transferase family 8
HEFJEAGE_01037 7.2e-166 arbZ I Phosphate acyltransferases
HEFJEAGE_01038 1e-17
HEFJEAGE_01039 0.0 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 C FAD binding domain
HEFJEAGE_01040 2.1e-171 K Transcriptional regulator, LysR family
HEFJEAGE_01041 1.2e-149 ydiN EGP Major Facilitator Superfamily
HEFJEAGE_01042 2.9e-96 S Membrane
HEFJEAGE_01043 3.5e-222 naiP EGP Major facilitator Superfamily
HEFJEAGE_01044 2.4e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HEFJEAGE_01045 7.3e-172 glk 2.7.1.2 G Glucokinase
HEFJEAGE_01047 8.4e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
HEFJEAGE_01048 9.4e-164 cpsY K Transcriptional regulator, LysR family
HEFJEAGE_01049 4.4e-129
HEFJEAGE_01050 6.3e-61 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEFJEAGE_01051 2.6e-256 V ABC-type multidrug transport system, ATPase and permease components
HEFJEAGE_01052 2.9e-13 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
HEFJEAGE_01056 1.5e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HEFJEAGE_01057 2.2e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
HEFJEAGE_01058 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEFJEAGE_01059 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEFJEAGE_01060 2.9e-29 secG U Preprotein translocase
HEFJEAGE_01061 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEFJEAGE_01062 8e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEFJEAGE_01065 1.9e-215 S FtsX-like permease family
HEFJEAGE_01066 1.8e-119 V ABC transporter, ATP-binding protein
HEFJEAGE_01068 7e-21 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HEFJEAGE_01069 5.3e-81
HEFJEAGE_01070 4.3e-83 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEFJEAGE_01071 3.6e-82 yjcF S Acetyltransferase (GNAT) domain
HEFJEAGE_01072 2.7e-143 sufC O FeS assembly ATPase SufC
HEFJEAGE_01073 4e-220 sufD O FeS assembly protein SufD
HEFJEAGE_01074 4.3e-225 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEFJEAGE_01075 4.3e-74 nifU C SUF system FeS assembly protein, NifU family
HEFJEAGE_01076 1.4e-275 sufB O assembly protein SufB
HEFJEAGE_01077 9.2e-73 cydD V abc transporter atp-binding protein
HEFJEAGE_01079 5.8e-10 N phage tail tape measure protein
HEFJEAGE_01080 3.3e-34 C Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
HEFJEAGE_01081 1.3e-42 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEFJEAGE_01082 1.5e-24 T CHASE
HEFJEAGE_01083 1.1e-181 gpsA 1.1.1.94 I Rossmann-like domain
HEFJEAGE_01084 2.7e-58 K sequence-specific DNA binding
HEFJEAGE_01085 3.3e-34
HEFJEAGE_01086 5.4e-14 L nuclease
HEFJEAGE_01087 2e-76 F DNA/RNA non-specific endonuclease
HEFJEAGE_01089 5.2e-175 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HEFJEAGE_01090 1.9e-65 S Core-2/I-Branching enzyme
HEFJEAGE_01091 6.2e-81 S Core-2/I-Branching enzyme
HEFJEAGE_01092 1e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
HEFJEAGE_01093 7.7e-151 cps1D M Domain of unknown function (DUF4422)
HEFJEAGE_01094 4.3e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
HEFJEAGE_01095 2.4e-172 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HEFJEAGE_01096 1.5e-184 M Glycosyl transferases group 1
HEFJEAGE_01097 5.1e-198 wbbI M transferase activity, transferring glycosyl groups
HEFJEAGE_01098 3.6e-263 epsIIL S Membrane protein involved in the export of O-antigen and teichoic acid
HEFJEAGE_01099 1.3e-178 M LicD family
HEFJEAGE_01100 2e-85 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HEFJEAGE_01101 5.9e-225
HEFJEAGE_01104 3.5e-31 bgl 3.2.1.21, 3.2.1.86 GT1 G beta-glucosidase activity
HEFJEAGE_01105 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEFJEAGE_01106 3.7e-28 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HEFJEAGE_01107 3.5e-18 yliE T EAL domain
HEFJEAGE_01108 3.9e-139
HEFJEAGE_01109 1.6e-07
HEFJEAGE_01110 3.9e-84 K DNA-templated transcription, initiation
HEFJEAGE_01111 4.2e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HEFJEAGE_01112 1.5e-167 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HEFJEAGE_01113 0.0 S Bacterial membrane protein, YfhO
HEFJEAGE_01114 1.3e-179 yfdH GT2 M Glycosyltransferase like family 2
HEFJEAGE_01115 5.5e-92 racA K Domain of unknown function (DUF1836)
HEFJEAGE_01116 1.7e-145 yitS S EDD domain protein, DegV family
HEFJEAGE_01117 6.8e-83 yliE T EAL domain
HEFJEAGE_01118 1.2e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HEFJEAGE_01119 4.7e-125 gpmB G Phosphoglycerate mutase family
HEFJEAGE_01120 8.1e-13
HEFJEAGE_01121 3.5e-106
HEFJEAGE_01122 7.4e-43
HEFJEAGE_01123 2.4e-90 S biotin transmembrane transporter activity
HEFJEAGE_01124 1.3e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HEFJEAGE_01125 4.7e-94 S ECF transporter, substrate-specific component
HEFJEAGE_01126 7e-14 S Domain of unknown function (DUF4430)
HEFJEAGE_01127 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HEFJEAGE_01128 6.7e-164 yvgN C Aldo keto reductase
HEFJEAGE_01129 3.5e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HEFJEAGE_01130 2e-80
HEFJEAGE_01131 4.6e-162 xth 3.1.11.2 L exodeoxyribonuclease III
HEFJEAGE_01132 4.1e-59 S glycolate biosynthetic process
HEFJEAGE_01133 1e-18 L haloacid dehalogenase-like hydrolase
HEFJEAGE_01134 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HEFJEAGE_01135 4.7e-185 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEFJEAGE_01136 2.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HEFJEAGE_01137 1.7e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEFJEAGE_01138 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEFJEAGE_01139 4.7e-171 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEFJEAGE_01140 9.5e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEFJEAGE_01141 9.1e-220 patA 2.6.1.1 E Aminotransferase
HEFJEAGE_01142 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEFJEAGE_01143 1.2e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
HEFJEAGE_01144 8.6e-95 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HEFJEAGE_01145 1.4e-156 hipB K Helix-turn-helix
HEFJEAGE_01146 8.5e-153 I alpha/beta hydrolase fold
HEFJEAGE_01147 4.4e-106 yjbF S SNARE associated Golgi protein
HEFJEAGE_01148 6.1e-93 J Acetyltransferase (GNAT) domain
HEFJEAGE_01149 2.2e-235 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEFJEAGE_01150 2.7e-97 K Sigma-70 region 2
HEFJEAGE_01151 3.7e-154 S Protein of unknown function (DUF3298)
HEFJEAGE_01152 6e-188 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFJEAGE_01153 2.2e-257 1.1.3.15 C FAD linked oxidases, C-terminal domain
HEFJEAGE_01154 9.4e-74 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEFJEAGE_01155 7.4e-142 metQ_4 P Belongs to the nlpA lipoprotein family
HEFJEAGE_01156 4.2e-91 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEFJEAGE_01158 4.1e-134 S amidohydrolase
HEFJEAGE_01159 5.3e-47 E Arginine ornithine antiporter
HEFJEAGE_01160 4.6e-181 E Arginine ornithine antiporter
HEFJEAGE_01180 2.8e-54 ribD 1.1.1.193, 3.5.4.26 H MafB19-like deaminase
HEFJEAGE_01181 1.7e-12 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HEFJEAGE_01182 2.1e-66 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HEFJEAGE_01183 1.3e-59 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HEFJEAGE_01184 7.7e-48 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HEFJEAGE_01185 1.4e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEFJEAGE_01186 1.5e-140 K LysR family
HEFJEAGE_01187 1.3e-119 3.6.1.27 I Acid phosphatase homologues
HEFJEAGE_01188 1e-260 mdr EGP Sugar (and other) transporter
HEFJEAGE_01189 1.1e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEFJEAGE_01195 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEFJEAGE_01196 4.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEFJEAGE_01197 3.9e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEFJEAGE_01198 7e-220 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEFJEAGE_01199 3.2e-53 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HEFJEAGE_01200 1.5e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEFJEAGE_01201 1.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEFJEAGE_01202 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEFJEAGE_01203 4.8e-42 rplGA J ribosomal protein
HEFJEAGE_01204 4.3e-43 ylxR K Protein of unknown function (DUF448)
HEFJEAGE_01205 6.8e-194 nusA K Participates in both transcription termination and antitermination
HEFJEAGE_01206 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HEFJEAGE_01207 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEFJEAGE_01208 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEFJEAGE_01209 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HEFJEAGE_01210 1.1e-144 cdsA 2.7.7.41 S Belongs to the CDS family
HEFJEAGE_01211 7.6e-124 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEFJEAGE_01212 1.4e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEFJEAGE_01213 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HEFJEAGE_01214 5.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEFJEAGE_01215 1.4e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
HEFJEAGE_01216 2.2e-190 yabB 2.1.1.223 L Methyltransferase small domain
HEFJEAGE_01217 1.4e-115 plsC 2.3.1.51 I Acyltransferase
HEFJEAGE_01218 5.3e-181 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEFJEAGE_01219 3.3e-250 yclM 2.7.2.4 E Belongs to the aspartokinase family
HEFJEAGE_01220 1e-212 hom 1.1.1.3 E homoserine dehydrogenase
HEFJEAGE_01221 2.6e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
HEFJEAGE_01222 0.0 mdlB V ABC transporter
HEFJEAGE_01223 0.0 mdlA V ABC transporter
HEFJEAGE_01224 2.3e-31 yneF S Uncharacterised protein family (UPF0154)
HEFJEAGE_01225 1.5e-33 ynzC S UPF0291 protein
HEFJEAGE_01226 3.5e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEFJEAGE_01227 1.8e-148 glcU U ribose uptake protein RbsU
HEFJEAGE_01228 3.6e-144 glnH ET ABC transporter substrate-binding protein
HEFJEAGE_01229 3.4e-97
HEFJEAGE_01230 0.0 lhr L DEAD DEAH box helicase
HEFJEAGE_01231 5.2e-248 P P-loop Domain of unknown function (DUF2791)
HEFJEAGE_01232 0.0 S TerB-C domain
HEFJEAGE_01233 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HEFJEAGE_01234 5.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEFJEAGE_01235 2.3e-229 snf 2.7.11.1 KL domain protein
HEFJEAGE_01236 1.8e-103 snf 2.7.11.1 KL domain protein
HEFJEAGE_01237 1.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HEFJEAGE_01238 1.8e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEFJEAGE_01239 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HEFJEAGE_01240 1.2e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEFJEAGE_01241 8.6e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEFJEAGE_01242 1.5e-73 pipD E Dipeptidase
HEFJEAGE_01243 9.7e-88 pipD E Dipeptidase
HEFJEAGE_01244 1.6e-16 pipD E Dipeptidase
HEFJEAGE_01245 2.2e-155 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEFJEAGE_01246 0.0 smc D Required for chromosome condensation and partitioning
HEFJEAGE_01247 3.1e-127 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEFJEAGE_01248 0.0 oppA E ABC transporter substrate-binding protein
HEFJEAGE_01249 0.0 oppA1 E ABC transporter substrate-binding protein
HEFJEAGE_01250 1.3e-157 oppC P Binding-protein-dependent transport system inner membrane component
HEFJEAGE_01251 7.7e-177 oppB P ABC transporter permease
HEFJEAGE_01252 2.4e-178 oppF P Belongs to the ABC transporter superfamily
HEFJEAGE_01253 1.1e-189 oppD P Belongs to the ABC transporter superfamily
HEFJEAGE_01254 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEFJEAGE_01255 7.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEFJEAGE_01256 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEFJEAGE_01257 1.3e-277 yloV S DAK2 domain fusion protein YloV
HEFJEAGE_01258 4.4e-56 asp S Asp23 family, cell envelope-related function
HEFJEAGE_01259 3.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HEFJEAGE_01260 4.2e-281 V ABC transporter transmembrane region
HEFJEAGE_01263 1.8e-30 D nuclear chromosome segregation
HEFJEAGE_01264 1.4e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
HEFJEAGE_01265 2.2e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEFJEAGE_01266 1.7e-116 KLT serine threonine protein kinase
HEFJEAGE_01267 1.8e-212 KLT serine threonine protein kinase
HEFJEAGE_01268 4.3e-138 stp 3.1.3.16 T phosphatase
HEFJEAGE_01269 4.1e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEFJEAGE_01270 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEFJEAGE_01271 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEFJEAGE_01272 2.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEFJEAGE_01273 1.1e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HEFJEAGE_01274 2.6e-49
HEFJEAGE_01275 4.3e-29 oppA E transmembrane transport
HEFJEAGE_01276 2.9e-14 oppA E ABC transporter, substratebinding protein
HEFJEAGE_01277 1.6e-46 oppA E transmembrane transport
HEFJEAGE_01278 7e-306 recN L May be involved in recombinational repair of damaged DNA
HEFJEAGE_01279 7.8e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HEFJEAGE_01280 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEFJEAGE_01281 1.7e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEFJEAGE_01282 8e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEFJEAGE_01283 4.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEFJEAGE_01284 1.8e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEFJEAGE_01285 8.1e-73 yqhY S Asp23 family, cell envelope-related function
HEFJEAGE_01286 9.2e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEFJEAGE_01287 1.5e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HEFJEAGE_01288 2.1e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HEFJEAGE_01289 9.9e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HEFJEAGE_01290 5.1e-65 arsC 1.20.4.1 P Belongs to the ArsC family
HEFJEAGE_01291 4e-90 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HEFJEAGE_01292 2.6e-60 livF E ABC transporter
HEFJEAGE_01293 3.1e-242 purD 6.3.4.13 F Belongs to the GARS family
HEFJEAGE_01294 4.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HEFJEAGE_01295 4.2e-109 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEFJEAGE_01296 2.3e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HEFJEAGE_01297 6.6e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEFJEAGE_01298 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEFJEAGE_01299 5.2e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEFJEAGE_01300 2.8e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEFJEAGE_01301 1.6e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HEFJEAGE_01302 3.8e-251 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEFJEAGE_01303 2.5e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEFJEAGE_01304 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEFJEAGE_01305 4.8e-41 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
HEFJEAGE_01306 3.3e-217 EGP Major Facilitator Superfamily
HEFJEAGE_01307 1.7e-79
HEFJEAGE_01308 1.8e-37
HEFJEAGE_01309 4.4e-54
HEFJEAGE_01310 0.0 S SH3-like domain
HEFJEAGE_01311 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HEFJEAGE_01313 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HEFJEAGE_01314 1.3e-216 EGP Major facilitator Superfamily
HEFJEAGE_01319 1e-12 asnB 6.3.5.4 E Aluminium induced protein
HEFJEAGE_01320 1.1e-259 asnB 6.3.5.4 E Aluminium induced protein
HEFJEAGE_01321 1.2e-160 spoU 2.1.1.185 J Methyltransferase
HEFJEAGE_01323 1.5e-47 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HEFJEAGE_01324 9.4e-46 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HEFJEAGE_01325 6.5e-50 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HEFJEAGE_01326 3.9e-142 G polysaccharide deacetylase
HEFJEAGE_01327 3.8e-10 G polysaccharide deacetylase
HEFJEAGE_01328 2.2e-205 nhaC C Na H antiporter NhaC
HEFJEAGE_01329 9.3e-22 nhaC C Na H antiporter NhaC
HEFJEAGE_01330 4.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HEFJEAGE_01340 1.8e-74
HEFJEAGE_01341 2.3e-184 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HEFJEAGE_01342 6.6e-119 dedA S SNARE-like domain protein
HEFJEAGE_01343 3.5e-106 S Protein of unknown function (DUF1461)
HEFJEAGE_01344 4.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEFJEAGE_01345 2.8e-83 yutD S Protein of unknown function (DUF1027)
HEFJEAGE_01346 1.9e-250 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HEFJEAGE_01347 5.6e-58
HEFJEAGE_01348 1.4e-181 ccpA K catabolite control protein A
HEFJEAGE_01349 1.8e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HEFJEAGE_01351 1.4e-27 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HEFJEAGE_01352 1.7e-39
HEFJEAGE_01353 5.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEFJEAGE_01354 3.6e-149 ykuT M mechanosensitive ion channel
HEFJEAGE_01355 6.7e-113 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEFJEAGE_01356 5.1e-66 yslB S Protein of unknown function (DUF2507)
HEFJEAGE_01357 1e-53 trxA O Belongs to the thioredoxin family
HEFJEAGE_01358 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEFJEAGE_01359 1e-40 yrzB S Belongs to the UPF0473 family
HEFJEAGE_01360 3.9e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEFJEAGE_01361 5.7e-42 yrzL S Belongs to the UPF0297 family
HEFJEAGE_01362 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEFJEAGE_01363 7.5e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEFJEAGE_01364 4.1e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HEFJEAGE_01365 6.4e-207 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEFJEAGE_01366 7.9e-282 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEFJEAGE_01367 3e-34 yajC U Preprotein translocase
HEFJEAGE_01368 1.6e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEFJEAGE_01369 6.4e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEFJEAGE_01370 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEFJEAGE_01371 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEFJEAGE_01372 1.8e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEFJEAGE_01373 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEFJEAGE_01374 1e-122 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEFJEAGE_01375 6.8e-302 uup S ABC transporter, ATP-binding protein
HEFJEAGE_01376 6.6e-190 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEFJEAGE_01377 3.5e-94 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HEFJEAGE_01378 1e-125 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HEFJEAGE_01379 3.4e-89 folT S ECF transporter, substrate-specific component
HEFJEAGE_01380 3.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
HEFJEAGE_01381 8.6e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEFJEAGE_01382 9.9e-55 yabA L Involved in initiation control of chromosome replication
HEFJEAGE_01383 1e-159 holB 2.7.7.7 L DNA polymerase III
HEFJEAGE_01384 2.4e-53 yaaQ S Cyclic-di-AMP receptor
HEFJEAGE_01385 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEFJEAGE_01386 1.4e-34 S Protein of unknown function (DUF2508)
HEFJEAGE_01387 1.5e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEFJEAGE_01388 3.5e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEFJEAGE_01389 6e-287 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEFJEAGE_01390 1.5e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEFJEAGE_01391 7.2e-112 rsmC 2.1.1.172 J Methyltransferase
HEFJEAGE_01392 1.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEFJEAGE_01393 1.6e-172
HEFJEAGE_01394 1.2e-45
HEFJEAGE_01395 1.9e-14 L Helix-turn-helix domain
HEFJEAGE_01396 1.2e-205 pbpX1 V Beta-lactamase
HEFJEAGE_01397 4.2e-214 pbpX1 V Beta-lactamase
HEFJEAGE_01398 1.6e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEFJEAGE_01399 4.8e-24 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HEFJEAGE_01401 3.9e-84 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEFJEAGE_01402 4.6e-14 P nitric oxide dioxygenase activity
HEFJEAGE_01403 2.2e-142 oppA E ABC transporter, substratebinding protein
HEFJEAGE_01404 1.4e-84 oppA E ABC transporter, substratebinding protein
HEFJEAGE_01405 1.8e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEFJEAGE_01406 1.1e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEFJEAGE_01407 1.4e-150 L Putative transposase DNA-binding domain
HEFJEAGE_01408 1.4e-74 L Putative transposase DNA-binding domain
HEFJEAGE_01409 8.5e-69
HEFJEAGE_01410 1.6e-230 amtB P ammonium transporter
HEFJEAGE_01411 8.3e-190 S Glycosyl transferase family 2
HEFJEAGE_01412 2e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEFJEAGE_01413 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEFJEAGE_01414 5.2e-101 nusG K Participates in transcription elongation, termination and antitermination
HEFJEAGE_01415 1.8e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEFJEAGE_01416 1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEFJEAGE_01417 3.3e-31 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEFJEAGE_01418 4.7e-96 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEFJEAGE_01419 1.8e-95 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEFJEAGE_01420 9.2e-114 4.2.99.20 S Alpha/beta hydrolase family
HEFJEAGE_01421 1.8e-33
HEFJEAGE_01422 2.4e-101 yvrI K sigma factor activity
HEFJEAGE_01423 2.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEFJEAGE_01424 9.4e-77 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEFJEAGE_01425 4.5e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEFJEAGE_01426 4.2e-106 3.6.1.67 F NUDIX domain
HEFJEAGE_01427 4.9e-162 K LysR substrate binding domain
HEFJEAGE_01428 3e-179 yeiH S Conserved hypothetical protein 698
HEFJEAGE_01429 1.3e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEFJEAGE_01431 1.7e-120 skfE V ATPases associated with a variety of cellular activities
HEFJEAGE_01432 8.7e-60 yvoA_1 K Transcriptional regulator, GntR family
HEFJEAGE_01433 1.9e-96 oppA E ABC transporter, substratebinding protein
HEFJEAGE_01434 1.9e-110 oppA E ABC transporter, substratebinding protein
HEFJEAGE_01435 4.3e-49 oppA E ABC transporter, substratebinding protein
HEFJEAGE_01436 3.4e-94 3.6.1.13 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEFJEAGE_01437 2.2e-232 6.3.2.4 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEFJEAGE_01438 1e-27 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
HEFJEAGE_01439 3.1e-13 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
HEFJEAGE_01440 8.5e-159 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEFJEAGE_01441 1.2e-199
HEFJEAGE_01442 8.9e-125 EGP Transmembrane secretion effector
HEFJEAGE_01443 1.2e-71 EGP Transmembrane secretion effector
HEFJEAGE_01444 2.7e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HEFJEAGE_01445 3.4e-73 2.7.13.3 T diguanylate cyclase
HEFJEAGE_01446 2.5e-20 5.99.1.2 T diguanylate cyclase
HEFJEAGE_01447 3.7e-16 5.99.1.2 T diguanylate cyclase
HEFJEAGE_01448 4.4e-109 T EAL domain
HEFJEAGE_01449 4.8e-11 5.99.1.2 T diguanylate cyclase
HEFJEAGE_01450 1.3e-85 S ECF-type riboflavin transporter, S component
HEFJEAGE_01451 2.1e-263 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HEFJEAGE_01452 1.5e-144 cbiQ P cobalt transport
HEFJEAGE_01453 0.0 ykoD P ABC transporter, ATP-binding protein
HEFJEAGE_01454 1.3e-99 S UPF0397 protein
HEFJEAGE_01455 7.6e-160 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HEFJEAGE_01456 1.7e-254 cycA E Amino acid permease
HEFJEAGE_01457 0.0 S ABC-type transport system involved in multi-copper enzyme maturation permease component
HEFJEAGE_01458 1.2e-168 ytrB V ABC transporter
HEFJEAGE_01459 6.1e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HEFJEAGE_01466 8e-88 L COG3547 Transposase and inactivated derivatives
HEFJEAGE_01473 3.6e-40 L DDE superfamily endonuclease
HEFJEAGE_01474 9.9e-100 sip L Belongs to the 'phage' integrase family
HEFJEAGE_01475 6.8e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HEFJEAGE_01476 8.7e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEFJEAGE_01477 4.5e-82 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEFJEAGE_01478 0.0 dnaK O Heat shock 70 kDa protein
HEFJEAGE_01479 2.4e-169 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEFJEAGE_01480 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEFJEAGE_01481 2e-75 srtA 3.4.22.70 M sortase family
HEFJEAGE_01482 3.2e-33 srtA 3.4.22.70 M sortase family
HEFJEAGE_01483 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HEFJEAGE_01484 9.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEFJEAGE_01485 3.3e-47 K DNA-binding transcription factor activity
HEFJEAGE_01486 1.9e-153 czcD P cation diffusion facilitator family transporter
HEFJEAGE_01487 1.2e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEFJEAGE_01488 2e-184 S AI-2E family transporter
HEFJEAGE_01489 7e-114 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HEFJEAGE_01490 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HEFJEAGE_01491 2.4e-161 lysR5 K LysR substrate binding domain
HEFJEAGE_01492 2.5e-259 glnPH2 P ABC transporter permease
HEFJEAGE_01493 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEFJEAGE_01494 1.6e-103 S Protein of unknown function (DUF4230)
HEFJEAGE_01495 1.7e-28 yjgN S Bacterial protein of unknown function (DUF898)
HEFJEAGE_01496 2.1e-138 yjgN S Bacterial protein of unknown function (DUF898)
HEFJEAGE_01497 1.8e-53 S Protein of unknown function (DUF2752)
HEFJEAGE_01498 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEFJEAGE_01499 9.8e-152 yitS S Uncharacterised protein, DegV family COG1307
HEFJEAGE_01500 1.6e-100 3.6.1.27 I Acid phosphatase homologues
HEFJEAGE_01501 1.2e-157
HEFJEAGE_01502 4.1e-164 lysR7 K LysR substrate binding domain
HEFJEAGE_01503 5.3e-309 yfiB1 V ABC transporter, ATP-binding protein
HEFJEAGE_01504 0.0 XK27_10035 V ABC transporter
HEFJEAGE_01506 1.2e-09 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_01507 3e-09 yliE T EAL domain
HEFJEAGE_01508 1.8e-07 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_01509 7.3e-169 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEFJEAGE_01510 4.1e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEFJEAGE_01511 1.6e-117 hlyIII S protein, hemolysin III
HEFJEAGE_01512 3.3e-155 DegV S Uncharacterised protein, DegV family COG1307
HEFJEAGE_01513 5.5e-36 yozE S Belongs to the UPF0346 family
HEFJEAGE_01514 7.4e-163 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEFJEAGE_01515 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEFJEAGE_01516 5.2e-153 dprA LU DNA protecting protein DprA
HEFJEAGE_01517 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEFJEAGE_01518 1.8e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEFJEAGE_01519 1.8e-164 xerC D Phage integrase, N-terminal SAM-like domain
HEFJEAGE_01520 4e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEFJEAGE_01521 1.5e-242 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEFJEAGE_01522 1.8e-175 lacX 5.1.3.3 G Aldose 1-epimerase
HEFJEAGE_01525 1.2e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEFJEAGE_01526 7.2e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HEFJEAGE_01527 1.2e-07 secY2 U SecY translocase
HEFJEAGE_01529 1.3e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEFJEAGE_01531 4.5e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEFJEAGE_01532 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HEFJEAGE_01533 5.7e-172 phoH T phosphate starvation-inducible protein PhoH
HEFJEAGE_01534 6.7e-98 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEFJEAGE_01535 2.9e-75 cdd 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEFJEAGE_01536 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEFJEAGE_01537 3.4e-135 recO L Involved in DNA repair and RecF pathway recombination
HEFJEAGE_01538 5.1e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HEFJEAGE_01539 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HEFJEAGE_01540 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEFJEAGE_01541 2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEFJEAGE_01542 6.2e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEFJEAGE_01543 3.3e-203 K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEFJEAGE_01544 2.8e-37 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEFJEAGE_01545 1.2e-42 celA 3.2.1.86 GT1 G beta-glucosidase activity
HEFJEAGE_01546 0.0 copB 3.6.3.4 P P-type ATPase
HEFJEAGE_01547 7.1e-102 mdt(A) EGP Major facilitator Superfamily
HEFJEAGE_01548 1.9e-173 2.1.1.72 V type I restriction-modification system
HEFJEAGE_01549 1.3e-247 2.1.1.72 V type I restriction-modification system
HEFJEAGE_01550 2e-25 3.1.21.3 V Type I restriction modification DNA specificity domain
HEFJEAGE_01551 2.4e-47 3.1.21.3 V type I restriction modification DNA specificity domain
HEFJEAGE_01552 1.9e-178 xerC L Belongs to the 'phage' integrase family
HEFJEAGE_01553 5.2e-57 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HEFJEAGE_01554 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HEFJEAGE_01555 3.8e-54
HEFJEAGE_01556 2.1e-86 L Transposase DDE domain
HEFJEAGE_01557 7.3e-127 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEFJEAGE_01558 8.8e-137 S Peptidase family M23
HEFJEAGE_01559 4.5e-79 mutT 3.6.1.55 F NUDIX domain
HEFJEAGE_01560 5.1e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
HEFJEAGE_01561 1.2e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEFJEAGE_01562 2.8e-243 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HEFJEAGE_01563 7.3e-23
HEFJEAGE_01564 5.2e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HEFJEAGE_01565 5.7e-160 xerD L Phage integrase, N-terminal SAM-like domain
HEFJEAGE_01566 3.9e-53 S Alpha beta hydrolase
HEFJEAGE_01567 9.3e-72 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HEFJEAGE_01568 5e-99 L DDE superfamily endonuclease
HEFJEAGE_01569 4.3e-23 L DDE superfamily endonuclease
HEFJEAGE_01570 0.0 lacS G Transporter
HEFJEAGE_01571 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HEFJEAGE_01572 1.9e-25 K purine nucleotide biosynthetic process
HEFJEAGE_01573 1.2e-106 galR K Transcriptional regulator
HEFJEAGE_01574 1.8e-231 isp2 L Transposase
HEFJEAGE_01575 3.1e-32 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HEFJEAGE_01576 1.9e-09 L COG3547 Transposase and inactivated derivatives
HEFJEAGE_01577 1.9e-09 L COG3547 Transposase and inactivated derivatives
HEFJEAGE_01579 2.5e-253 pipD M Peptidase family C69
HEFJEAGE_01580 1.8e-173 citR K Putative sugar-binding domain
HEFJEAGE_01581 2.2e-34 lysM M LysM domain
HEFJEAGE_01582 0.0 pepN 3.4.11.2 E aminopeptidase
HEFJEAGE_01583 1.1e-29 drgA C coenzyme F420-1:gamma-L-glutamate ligase activity
HEFJEAGE_01584 8.3e-08 1.13.11.79 C Nitroreductase family
HEFJEAGE_01585 5.9e-227 S Putative peptidoglycan binding domain
HEFJEAGE_01586 2.3e-116
HEFJEAGE_01587 6.4e-139 S Belongs to the UPF0246 family
HEFJEAGE_01588 2.5e-18 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HEFJEAGE_01589 2.2e-115 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HEFJEAGE_01590 2.1e-88 ygfC K transcriptional regulator (TetR family)
HEFJEAGE_01591 3.3e-182 hrtB V ABC transporter permease
HEFJEAGE_01592 3.7e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HEFJEAGE_01593 8e-171 K WYL domain
HEFJEAGE_01594 1.3e-66 S pyridoxamine 5-phosphate
HEFJEAGE_01595 5.9e-11 K LytTr DNA-binding domain
HEFJEAGE_01596 1.3e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEFJEAGE_01597 6.3e-140
HEFJEAGE_01599 1.7e-103
HEFJEAGE_01600 9.6e-118 V AAA domain, putative AbiEii toxin, Type IV TA system
HEFJEAGE_01601 1.1e-16
HEFJEAGE_01602 4.8e-276 pipD E Dipeptidase
HEFJEAGE_01603 1.5e-97 K WHG domain
HEFJEAGE_01604 4.9e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HEFJEAGE_01605 5e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
HEFJEAGE_01606 1.6e-143 3.1.3.48 T Tyrosine phosphatase family
HEFJEAGE_01607 6.8e-189 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEFJEAGE_01608 2.4e-87 cvpA S Colicin V production protein
HEFJEAGE_01609 7.4e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HEFJEAGE_01610 7.4e-144 noc K Belongs to the ParB family
HEFJEAGE_01611 2.6e-138 soj D Sporulation initiation inhibitor
HEFJEAGE_01612 3.1e-156 spo0J K Belongs to the ParB family
HEFJEAGE_01613 2.5e-45 yyzM S Bacterial protein of unknown function (DUF951)
HEFJEAGE_01614 6.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEFJEAGE_01615 1.8e-136 XK27_01040 S Protein of unknown function (DUF1129)
HEFJEAGE_01616 5.5e-303 V ABC transporter, ATP-binding protein
HEFJEAGE_01617 0.0 ndvA V ABC transporter
HEFJEAGE_01618 1e-122 K response regulator
HEFJEAGE_01619 6.5e-221 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HEFJEAGE_01620 6.4e-298 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEFJEAGE_01621 1.4e-144 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HEFJEAGE_01622 9.8e-135 fruR K DeoR C terminal sensor domain
HEFJEAGE_01623 2.9e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HEFJEAGE_01624 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HEFJEAGE_01625 1e-145 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HEFJEAGE_01626 3.8e-119 fhuC P ABC transporter
HEFJEAGE_01627 8e-135 znuB U ABC 3 transport family
HEFJEAGE_01628 4.7e-69 KT response to antibiotic
HEFJEAGE_01629 6.2e-105 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HEFJEAGE_01630 0.0 pepF E oligoendopeptidase F
HEFJEAGE_01631 1.1e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HEFJEAGE_01632 7.9e-16
HEFJEAGE_01633 8.1e-293 S ABC transporter, ATP-binding protein
HEFJEAGE_01634 1.3e-134 thrE S Putative threonine/serine exporter
HEFJEAGE_01635 2.7e-85 S Threonine/Serine exporter, ThrE
HEFJEAGE_01636 1.4e-68
HEFJEAGE_01637 2.2e-111
HEFJEAGE_01638 5.1e-295 S O-antigen ligase like membrane protein
HEFJEAGE_01639 7.2e-45
HEFJEAGE_01640 6.5e-96 gmk2 2.7.4.8 F Guanylate kinase homologues.
HEFJEAGE_01641 5.6e-83 M NlpC P60 family
HEFJEAGE_01642 1e-198 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFJEAGE_01643 6.5e-76 M NlpC/P60 family
HEFJEAGE_01644 1.2e-106 M NlpC P60 family protein
HEFJEAGE_01645 9.9e-121 M NlpC P60 family protein
HEFJEAGE_01646 1.1e-115 M NlpC P60 family protein
HEFJEAGE_01647 1e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEFJEAGE_01648 9.9e-178 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HEFJEAGE_01649 6.8e-111 epsB M biosynthesis protein
HEFJEAGE_01650 5.2e-115 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HEFJEAGE_01651 1.2e-148 ywqE 3.1.3.48 GM PHP domain protein
HEFJEAGE_01652 4.4e-123 rfbP M Bacterial sugar transferase
HEFJEAGE_01653 5.7e-183 M Glycosyl transferase 4-like
HEFJEAGE_01654 5.5e-198 2.4.1.21 GT4,GT5 G Glycosyl transferases group 1
HEFJEAGE_01655 1e-229 MA20_17390 GT4 M Glycosyltransferase Family 4
HEFJEAGE_01656 1.1e-186 S Glycosyltransferase like family 2
HEFJEAGE_01657 9.8e-181 wzy S EpsG family
HEFJEAGE_01658 1e-67 GT8 S Protein conserved in bacteria
HEFJEAGE_01659 1.1e-170 cpsJ S glycosyl transferase family 2
HEFJEAGE_01660 1.5e-69 L DDE superfamily endonuclease
HEFJEAGE_01661 2.7e-205 S Membrane protein involved in the export of O-antigen and teichoic acid
HEFJEAGE_01662 2.9e-24
HEFJEAGE_01663 4.5e-52 XK27_01125 L IS66 Orf2 like protein
HEFJEAGE_01664 1.1e-128 K SIR2-like domain
HEFJEAGE_01665 3.8e-170 lysR7 K LysR substrate binding domain
HEFJEAGE_01666 1.4e-27 1.3.5.4 C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
HEFJEAGE_01667 7.7e-29 1.3.5.4 C FAD binding domain
HEFJEAGE_01668 9.8e-73 1.3.5.4 C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
HEFJEAGE_01669 3.2e-55 1.3.5.4 C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
HEFJEAGE_01670 9.9e-72 L nuclease
HEFJEAGE_01671 4.2e-19 L nuclease
HEFJEAGE_01672 5.3e-156 F DNA/RNA non-specific endonuclease
HEFJEAGE_01673 3.3e-11
HEFJEAGE_01674 2.4e-174 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HEFJEAGE_01675 3.6e-200 KQ Hypothetical methyltransferase
HEFJEAGE_01676 1.7e-206 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEFJEAGE_01677 9.1e-156 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEFJEAGE_01678 4.8e-116 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HEFJEAGE_01679 7.6e-188 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEFJEAGE_01680 4.5e-24 higA K Helix-turn-helix XRE-family like proteins
HEFJEAGE_01681 3.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HEFJEAGE_01682 4.1e-63 S ABC transporter, ATP-binding protein
HEFJEAGE_01683 2.4e-26
HEFJEAGE_01684 2.5e-29 L Transposase
HEFJEAGE_01685 8.4e-10 L COG3547 Transposase and inactivated derivatives
HEFJEAGE_01689 4e-49 S Domain of Unknown Function with PDB structure (DUF3862)
HEFJEAGE_01691 2.6e-123 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEFJEAGE_01692 4.7e-126 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HEFJEAGE_01693 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HEFJEAGE_01694 1.7e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEFJEAGE_01695 3.1e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HEFJEAGE_01696 1.9e-77 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEFJEAGE_01697 3e-68 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEFJEAGE_01698 8.8e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEFJEAGE_01699 6.3e-123 IQ reductase
HEFJEAGE_01700 7.4e-180 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HEFJEAGE_01701 1e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEFJEAGE_01702 3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEFJEAGE_01703 1.6e-39 K AI-2E family transporter
HEFJEAGE_01704 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEFJEAGE_01705 2.3e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HEFJEAGE_01706 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEFJEAGE_01707 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEFJEAGE_01708 1.8e-173 prmA J Ribosomal protein L11 methyltransferase
HEFJEAGE_01709 1.4e-89 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEFJEAGE_01710 1e-222 yjjP S Putative threonine/serine exporter
HEFJEAGE_01711 4.8e-221 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HEFJEAGE_01712 1.5e-217 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HEFJEAGE_01713 4.2e-195 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HEFJEAGE_01714 6.7e-229 sptS 2.7.13.3 T Histidine kinase
HEFJEAGE_01715 1.1e-118 K response regulator
HEFJEAGE_01716 3.1e-110 2.7.6.5 T Region found in RelA / SpoT proteins
HEFJEAGE_01717 2.7e-160 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
HEFJEAGE_01718 1.2e-174 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEFJEAGE_01719 3.4e-117 casE S CRISPR_assoc
HEFJEAGE_01720 5.5e-132 casD S CRISPR-associated protein (Cas_Cas5)
HEFJEAGE_01721 4.5e-181 casC L CT1975-like protein
HEFJEAGE_01722 9.8e-109 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
HEFJEAGE_01723 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
HEFJEAGE_01724 0.0 cas3 L CRISPR-associated helicase cas3
HEFJEAGE_01728 7.2e-202 argH 2.3.1.1, 4.3.2.1 E argininosuccinate lyase
HEFJEAGE_01729 1.6e-70
HEFJEAGE_01730 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEFJEAGE_01731 1.5e-26
HEFJEAGE_01732 1.1e-113 K DNA-binding transcription factor activity
HEFJEAGE_01733 2.8e-12 K Transcriptional regulator, LysR family
HEFJEAGE_01734 7.6e-166 K LysR substrate binding domain
HEFJEAGE_01735 0.0 S Bacterial membrane protein YfhO
HEFJEAGE_01736 3.9e-229 S Tetratricopeptide repeat protein
HEFJEAGE_01737 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEFJEAGE_01738 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HEFJEAGE_01739 4.2e-212 rpsA 1.17.7.4 J Ribosomal protein S1
HEFJEAGE_01740 8.6e-108 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HEFJEAGE_01742 8.6e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEFJEAGE_01743 9.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEFJEAGE_01744 3.4e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEFJEAGE_01745 6e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEFJEAGE_01746 4.4e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEFJEAGE_01747 5.4e-164 xerD D recombinase XerD
HEFJEAGE_01748 4e-164 cvfB S S1 domain
HEFJEAGE_01749 1e-88 I Acyltransferase family
HEFJEAGE_01751 1.3e-38 ssuB P anion transmembrane transporter activity
HEFJEAGE_01752 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HEFJEAGE_01753 2e-180 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEFJEAGE_01754 0.0 dnaE 2.7.7.7 L DNA polymerase
HEFJEAGE_01755 4.3e-29 S Protein of unknown function (DUF2929)
HEFJEAGE_01756 1.7e-88 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEFJEAGE_01757 5.4e-54 gmuR K UbiC transcription regulator-associated domain protein
HEFJEAGE_01758 1.9e-15 gmuR K UTRA
HEFJEAGE_01759 3.2e-98 ywlG S Belongs to the UPF0340 family
HEFJEAGE_01761 4.9e-34
HEFJEAGE_01762 0.0 L SNF2 family N-terminal domain
HEFJEAGE_01763 5.3e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HEFJEAGE_01764 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HEFJEAGE_01765 7.7e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEFJEAGE_01766 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEFJEAGE_01767 0.0 oatA I Acyltransferase
HEFJEAGE_01768 8.1e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEFJEAGE_01769 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEFJEAGE_01770 3.2e-183 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HEFJEAGE_01771 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HEFJEAGE_01772 2.5e-175 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFJEAGE_01773 2.5e-208 S Amidohydrolase
HEFJEAGE_01774 1.2e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEFJEAGE_01775 1e-76 argR K Regulates arginine biosynthesis genes
HEFJEAGE_01776 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HEFJEAGE_01777 2.8e-168 K LysR substrate binding domain
HEFJEAGE_01778 5.1e-226 EK Aminotransferase, class I
HEFJEAGE_01779 4.1e-71 E Methionine synthase
HEFJEAGE_01782 5.4e-18 S NgoFVII restriction endonuclease
HEFJEAGE_01783 1.9e-51
HEFJEAGE_01784 2.2e-159 bepIM 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HEFJEAGE_01785 1.3e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HEFJEAGE_01786 2e-56 qorB 1.6.5.2 GM NmrA-like family
HEFJEAGE_01787 2.8e-32 qorB 1.6.5.2 GM epimerase
HEFJEAGE_01788 1.4e-72 K Transcriptional regulator
HEFJEAGE_01789 8.6e-84 S YcxB-like protein
HEFJEAGE_01790 3.3e-100 T integral membrane protein
HEFJEAGE_01791 0.0 L Helicase C-terminal domain protein
HEFJEAGE_01792 2.9e-91 S ECF-type riboflavin transporter, S component
HEFJEAGE_01793 1.8e-153 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HEFJEAGE_01794 2.8e-28 K Acetyltransferase (GNAT) domain
HEFJEAGE_01795 9.4e-11 K Acetyltransferase (GNAT) domain
HEFJEAGE_01796 1e-239 lysA2 M Glycosyl hydrolases family 25
HEFJEAGE_01797 4.1e-256 L Transposase
HEFJEAGE_01798 1.9e-52 repA S Replication initiator protein A
HEFJEAGE_01799 1.9e-43 relB L Addiction module antitoxin, RelB DinJ family
HEFJEAGE_01800 2e-149 larE S NAD synthase
HEFJEAGE_01801 8.6e-70 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HEFJEAGE_01802 6.5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
HEFJEAGE_01803 1e-129 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HEFJEAGE_01804 4.2e-119 larB S AIR carboxylase
HEFJEAGE_01805 2.5e-239 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HEFJEAGE_01806 2e-116 K Crp-like helix-turn-helix domain
HEFJEAGE_01807 1.7e-179 nikMN P PDGLE domain
HEFJEAGE_01808 2.4e-125 cbiO P ABC transporter
HEFJEAGE_01809 3.3e-10
HEFJEAGE_01810 7.9e-132 ybbM S Uncharacterised protein family (UPF0014)
HEFJEAGE_01811 2e-112 ybbL S ABC transporter, ATP-binding protein
HEFJEAGE_01813 1e-20
HEFJEAGE_01814 0.0 KLT Protein kinase domain
HEFJEAGE_01815 1.8e-246 msbA2 3.6.3.44 V ABC transporter
HEFJEAGE_01816 1.1e-31 msbA2 3.6.3.44 V ABC transporter
HEFJEAGE_01817 5.4e-25
HEFJEAGE_01819 1.2e-191 2.7.13.3 T GHKL domain
HEFJEAGE_01820 6.2e-140 K LytTr DNA-binding domain
HEFJEAGE_01821 4.7e-83 V ABC-type multidrug transport system, ATPase and permease components
HEFJEAGE_01822 9.8e-74 V ABC-type multidrug transport system, ATPase and permease components
HEFJEAGE_01824 5.8e-121 yhiD S MgtC family
HEFJEAGE_01826 1.1e-68
HEFJEAGE_01827 0.0 V ATPases associated with a variety of cellular activities
HEFJEAGE_01828 3.1e-228 MA20_36090 S Protein of unknown function (DUF2974)
HEFJEAGE_01829 9.8e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEFJEAGE_01830 4e-75 rplI J Binds to the 23S rRNA
HEFJEAGE_01831 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HEFJEAGE_01832 3.3e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEFJEAGE_01833 1.4e-88 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEFJEAGE_01834 5.1e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HEFJEAGE_01835 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEFJEAGE_01836 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEFJEAGE_01837 2.2e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEFJEAGE_01838 2.2e-37 yaaA S S4 domain protein YaaA
HEFJEAGE_01839 5.3e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEFJEAGE_01840 3e-243 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEFJEAGE_01841 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HEFJEAGE_01842 1.4e-62 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEFJEAGE_01843 2.6e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEFJEAGE_01844 2.4e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEFJEAGE_01845 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEFJEAGE_01846 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HEFJEAGE_01847 2.8e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEFJEAGE_01848 1.4e-74
HEFJEAGE_01849 5.4e-84
HEFJEAGE_01850 4.4e-92
HEFJEAGE_01851 1.9e-98
HEFJEAGE_01853 1.2e-147 yliE T Putative diguanylate phosphodiesterase
HEFJEAGE_01854 5.9e-64 yliE T domain protein
HEFJEAGE_01855 9e-186 arbY M Glycosyl transferase family 8
HEFJEAGE_01856 6.6e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEFJEAGE_01857 2.9e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HEFJEAGE_01858 5.4e-49
HEFJEAGE_01859 3.1e-264 pepC 3.4.22.40 E Peptidase C1-like family
HEFJEAGE_01861 2.4e-183 S AAA domain
HEFJEAGE_01862 2.1e-79 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEFJEAGE_01863 8.3e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEFJEAGE_01864 5.2e-29
HEFJEAGE_01865 2.6e-28
HEFJEAGE_01866 6.2e-128 pgm3 G Belongs to the phosphoglycerate mutase family
HEFJEAGE_01867 1.7e-51 S membrane transporter protein
HEFJEAGE_01868 4.4e-37 S membrane transporter protein
HEFJEAGE_01869 1e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HEFJEAGE_01870 3.4e-94 wecD K Acetyltransferase (GNAT) family
HEFJEAGE_01871 4.8e-196 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEFJEAGE_01872 8.8e-09 3.5.2.6 V Beta-lactamase
HEFJEAGE_01873 2.8e-38 3.5.2.6 V Beta-lactamase
HEFJEAGE_01874 6.8e-136 ybbH_2 K Helix-turn-helix domain, rpiR family
HEFJEAGE_01875 1.4e-275 pepV 3.5.1.18 E dipeptidase PepV
HEFJEAGE_01876 1.7e-47 cycA E Amino acid permease
HEFJEAGE_01877 1.4e-165 cycA E Amino acid permease
HEFJEAGE_01878 1.3e-07 lacR K DeoR C terminal sensor domain
HEFJEAGE_01879 4.2e-69 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HEFJEAGE_01880 8.5e-87 D nuclear chromosome segregation
HEFJEAGE_01882 5.3e-77 M LysM domain protein
HEFJEAGE_01886 7.2e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEFJEAGE_01887 4.3e-283 thrC 4.2.3.1 E Threonine synthase
HEFJEAGE_01891 7.2e-100 K Acetyltransferase (GNAT) domain
HEFJEAGE_01892 9.9e-106 yiiE S Protein of unknown function (DUF1211)
HEFJEAGE_01893 1.1e-23
HEFJEAGE_01894 4.6e-135 scrR K Transcriptional regulator, LacI family
HEFJEAGE_01895 3e-159 scrB 3.2.1.26 GH32 G invertase
HEFJEAGE_01896 7.8e-79 2.7.1.199, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEFJEAGE_01897 1.9e-200 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEFJEAGE_01898 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEFJEAGE_01899 2.1e-81 G Belongs to the glycosyl hydrolase 13 family
HEFJEAGE_01900 8.9e-80 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HEFJEAGE_01901 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HEFJEAGE_01902 1e-276 E Amino acid permease
HEFJEAGE_01903 2.9e-31 L Transposase and inactivated derivatives, IS30 family
HEFJEAGE_01904 6.5e-205 G Major Facilitator Superfamily
HEFJEAGE_01905 6.1e-28
HEFJEAGE_01906 1.9e-207 G Major Facilitator Superfamily
HEFJEAGE_01907 2.1e-202 L COG2826 Transposase and inactivated derivatives, IS30 family
HEFJEAGE_01909 6.3e-54 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HEFJEAGE_01910 1.5e-126 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HEFJEAGE_01911 2.8e-21 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HEFJEAGE_01912 9.3e-52 oxlT P Major Facilitator Superfamily
HEFJEAGE_01913 5.2e-145 oxlT P Major Facilitator Superfamily
HEFJEAGE_01915 6.6e-18 K sequence-specific DNA binding
HEFJEAGE_01916 2.4e-47
HEFJEAGE_01917 0.0 recQ1 L Helicase conserved C-terminal domain
HEFJEAGE_01918 1.3e-187 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEFJEAGE_01919 1.6e-07 K Helix-turn-helix domain
HEFJEAGE_01921 1.2e-162 3.5.2.6 M NlpC/P60 family
HEFJEAGE_01922 4.5e-247 cycA E Amino acid permease
HEFJEAGE_01924 1.6e-63 manO S Domain of unknown function (DUF956)
HEFJEAGE_01925 3.9e-170 manN G system, mannose fructose sorbose family IID component
HEFJEAGE_01926 1.9e-139 manY G PTS system
HEFJEAGE_01927 2.3e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HEFJEAGE_01928 5.5e-83 L DDE superfamily endonuclease
HEFJEAGE_01929 2.5e-132 L DDE superfamily endonuclease

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)