ORF_ID e_value Gene_name EC_number CAZy COGs Description
FKIEMMFL_00001 3.2e-25 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
FKIEMMFL_00002 6.6e-281 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
FKIEMMFL_00003 8.4e-265 frdC 1.3.5.4 C FAD binding domain
FKIEMMFL_00004 3.4e-113 metI P ABC transporter permease
FKIEMMFL_00005 5.3e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FKIEMMFL_00006 3.2e-121 metQ2 P Belongs to the nlpA lipoprotein family
FKIEMMFL_00007 0.0 aha1 P E1-E2 ATPase
FKIEMMFL_00008 1.1e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FKIEMMFL_00009 1.8e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FKIEMMFL_00010 2.9e-122 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
FKIEMMFL_00011 1.2e-64
FKIEMMFL_00012 0.0 E ABC transporter, substratebinding protein
FKIEMMFL_00014 1.1e-124 pnb C nitroreductase
FKIEMMFL_00016 6.1e-259 I Protein of unknown function (DUF2974)
FKIEMMFL_00017 6.3e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
FKIEMMFL_00018 1.4e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FKIEMMFL_00019 2.1e-212 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FKIEMMFL_00020 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKIEMMFL_00021 4.5e-149
FKIEMMFL_00022 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FKIEMMFL_00023 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FKIEMMFL_00024 1.6e-33 rpsT J Binds directly to 16S ribosomal RNA
FKIEMMFL_00025 1e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
FKIEMMFL_00026 0.0 comEC S Competence protein ComEC
FKIEMMFL_00027 1.1e-69 comEA L Competence protein ComEA
FKIEMMFL_00028 7.8e-191 ylbL T Belongs to the peptidase S16 family
FKIEMMFL_00029 7.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FKIEMMFL_00030 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
FKIEMMFL_00031 1.1e-53 ylbG S UPF0298 protein
FKIEMMFL_00032 2.2e-213 ftsW D Belongs to the SEDS family
FKIEMMFL_00033 0.0 typA T GTP-binding protein TypA
FKIEMMFL_00034 4.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FKIEMMFL_00035 2.7e-35 ykzG S Belongs to the UPF0356 family
FKIEMMFL_00036 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FKIEMMFL_00037 1.8e-251 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
FKIEMMFL_00038 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FKIEMMFL_00039 1e-103 S Repeat protein
FKIEMMFL_00040 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
FKIEMMFL_00041 3.5e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FKIEMMFL_00042 3.2e-56 XK27_04120 S Putative amino acid metabolism
FKIEMMFL_00043 2.8e-213 iscS 2.8.1.7 E Aminotransferase class V
FKIEMMFL_00044 3.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FKIEMMFL_00045 5.4e-19
FKIEMMFL_00046 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
FKIEMMFL_00047 1.5e-32 cspA K 'Cold-shock' DNA-binding domain
FKIEMMFL_00048 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FKIEMMFL_00049 9.1e-147 ylmH S S4 domain protein
FKIEMMFL_00050 7.6e-46 yggT S YGGT family
FKIEMMFL_00051 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FKIEMMFL_00052 3.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FKIEMMFL_00053 2.2e-241 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FKIEMMFL_00054 2.3e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FKIEMMFL_00055 1.2e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FKIEMMFL_00056 5.6e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FKIEMMFL_00057 2.7e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FKIEMMFL_00058 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
FKIEMMFL_00059 4.8e-55 ftsL D Cell division protein FtsL
FKIEMMFL_00060 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FKIEMMFL_00061 1.6e-76 mraZ K Belongs to the MraZ family
FKIEMMFL_00062 5.7e-55 S Protein of unknown function (DUF3397)
FKIEMMFL_00064 1.1e-95 mreD
FKIEMMFL_00065 8.2e-138 mreC M Involved in formation and maintenance of cell shape
FKIEMMFL_00066 2.6e-175 mreB D cell shape determining protein MreB
FKIEMMFL_00067 1.2e-114 radC L DNA repair protein
FKIEMMFL_00068 6.8e-127 S Haloacid dehalogenase-like hydrolase
FKIEMMFL_00069 2.6e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FKIEMMFL_00070 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FKIEMMFL_00071 7.8e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FKIEMMFL_00072 4.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FKIEMMFL_00073 1.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
FKIEMMFL_00074 4.9e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FKIEMMFL_00075 1.2e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FKIEMMFL_00076 1e-81 yueI S Protein of unknown function (DUF1694)
FKIEMMFL_00077 1.6e-241 rarA L recombination factor protein RarA
FKIEMMFL_00078 1.3e-42
FKIEMMFL_00079 3e-78 usp6 T universal stress protein
FKIEMMFL_00080 2.7e-219 rodA D Belongs to the SEDS family
FKIEMMFL_00081 1.7e-34 S Protein of unknown function (DUF2969)
FKIEMMFL_00082 7.4e-48 yidD S Could be involved in insertion of integral membrane proteins into the membrane
FKIEMMFL_00083 6.1e-177 mbl D Cell shape determining protein MreB Mrl
FKIEMMFL_00084 3.9e-32 ywzB S Protein of unknown function (DUF1146)
FKIEMMFL_00085 4.8e-73 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
FKIEMMFL_00086 1.9e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FKIEMMFL_00087 2.4e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FKIEMMFL_00088 6.5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FKIEMMFL_00089 1.8e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FKIEMMFL_00090 4.2e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FKIEMMFL_00091 3.1e-28 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FKIEMMFL_00092 4.2e-127 atpB C it plays a direct role in the translocation of protons across the membrane
FKIEMMFL_00093 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FKIEMMFL_00094 9.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FKIEMMFL_00095 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FKIEMMFL_00096 2.1e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FKIEMMFL_00097 1.4e-112 tdk 2.7.1.21 F thymidine kinase
FKIEMMFL_00098 3.2e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
FKIEMMFL_00099 4.3e-34
FKIEMMFL_00100 7.6e-191 ampC V Beta-lactamase
FKIEMMFL_00103 3.2e-178 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00104 1.4e-23 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00105 6.2e-257 pgi 5.3.1.9 G Belongs to the GPI family
FKIEMMFL_00106 1.1e-107 vanZ V VanZ like family
FKIEMMFL_00107 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FKIEMMFL_00108 9.1e-276 T PhoQ Sensor
FKIEMMFL_00109 3e-133 K Transcriptional regulatory protein, C terminal
FKIEMMFL_00112 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FKIEMMFL_00113 1e-184 ytxK 2.1.1.72 L N-6 DNA Methylase
FKIEMMFL_00114 2.5e-10 comGF U Putative Competence protein ComGF
FKIEMMFL_00116 3e-75
FKIEMMFL_00117 6.5e-51 comGC U competence protein ComGC
FKIEMMFL_00118 1.3e-158 comGB NU type II secretion system
FKIEMMFL_00119 4.4e-180 comGA NU Type II IV secretion system protein
FKIEMMFL_00120 1.4e-130 yebC K Transcriptional regulatory protein
FKIEMMFL_00121 7.7e-94 S VanZ like family
FKIEMMFL_00122 1.2e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
FKIEMMFL_00123 8.9e-158 rssA S Phospholipase, patatin family
FKIEMMFL_00124 2.2e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKIEMMFL_00125 0.0 E Amino acid permease
FKIEMMFL_00126 1.7e-63 GM epimerase
FKIEMMFL_00127 6.3e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FKIEMMFL_00128 3.1e-66
FKIEMMFL_00129 1.5e-25
FKIEMMFL_00130 1.7e-125 T Diguanylate cyclase, GGDEF domain
FKIEMMFL_00131 5.2e-119 T Diguanylate cyclase, GGDEF domain
FKIEMMFL_00132 1e-181 yliE T Putative diguanylate phosphodiesterase
FKIEMMFL_00133 4.3e-149 T diguanylate cyclase activity
FKIEMMFL_00134 4.4e-138
FKIEMMFL_00135 5e-60 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FKIEMMFL_00136 2.5e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FKIEMMFL_00137 0.0 copA 3.6.3.54 P P-type ATPase
FKIEMMFL_00138 8.5e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
FKIEMMFL_00139 1.4e-77 atkY K Copper transport repressor CopY TcrY
FKIEMMFL_00140 1.1e-56 V peptidase activity
FKIEMMFL_00141 6.8e-150 S hydrolase
FKIEMMFL_00142 2e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKIEMMFL_00143 1.5e-164 ybbR S YbbR-like protein
FKIEMMFL_00144 4.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FKIEMMFL_00145 9e-206 potD P ABC transporter
FKIEMMFL_00146 3.9e-129 potC P ABC transporter permease
FKIEMMFL_00147 1.1e-144 potB P ABC transporter permease
FKIEMMFL_00148 1.4e-203 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
FKIEMMFL_00149 2.9e-162 murB 1.3.1.98 M Cell wall formation
FKIEMMFL_00150 1.2e-97 dnaQ 2.7.7.7 L DNA polymerase III
FKIEMMFL_00151 4.6e-85 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
FKIEMMFL_00152 9.7e-183 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
FKIEMMFL_00153 2.3e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FKIEMMFL_00154 3.7e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
FKIEMMFL_00155 8e-105
FKIEMMFL_00156 5.1e-23 3.2.2.20 K acetyltransferase
FKIEMMFL_00157 5.7e-27 3.2.2.20 K acetyltransferase
FKIEMMFL_00158 8.4e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FKIEMMFL_00159 3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
FKIEMMFL_00160 2.2e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FKIEMMFL_00161 1.8e-212 cggR K Putative sugar-binding domain
FKIEMMFL_00163 1.9e-112 XK27_08845 S ABC transporter, ATP-binding protein
FKIEMMFL_00164 1.5e-49 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
FKIEMMFL_00165 3.4e-29 ABC-SBP S ABC transporter substrate binding protein
FKIEMMFL_00166 3.5e-285
FKIEMMFL_00167 5.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FKIEMMFL_00168 1.5e-169 whiA K May be required for sporulation
FKIEMMFL_00169 1.4e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
FKIEMMFL_00170 2.4e-164 rapZ S Displays ATPase and GTPase activities
FKIEMMFL_00171 2.3e-84 dmpA 3.4.11.19 EQ Peptidase family S58
FKIEMMFL_00173 7.2e-124 E D-aminopeptidase
FKIEMMFL_00174 7.4e-92 S Short repeat of unknown function (DUF308)
FKIEMMFL_00175 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FKIEMMFL_00176 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FKIEMMFL_00177 8.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FKIEMMFL_00178 5e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
FKIEMMFL_00179 1.5e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FKIEMMFL_00180 1.2e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FKIEMMFL_00181 9.1e-31
FKIEMMFL_00182 5.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FKIEMMFL_00183 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FKIEMMFL_00184 1.6e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FKIEMMFL_00185 2.3e-122 comFC S Competence protein
FKIEMMFL_00186 2.7e-246 comFA L Helicase C-terminal domain protein
FKIEMMFL_00187 4.7e-117 yvyE 3.4.13.9 S YigZ family
FKIEMMFL_00188 1.1e-212 tagO 2.7.8.33, 2.7.8.35 M transferase
FKIEMMFL_00189 5.1e-221 rny S Endoribonuclease that initiates mRNA decay
FKIEMMFL_00190 4.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FKIEMMFL_00191 2.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FKIEMMFL_00192 1.7e-106 ymfM S Helix-turn-helix domain
FKIEMMFL_00193 5.2e-133 IQ Enoyl-(Acyl carrier protein) reductase
FKIEMMFL_00194 1.8e-237 S Peptidase M16
FKIEMMFL_00195 4.5e-230 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
FKIEMMFL_00196 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
FKIEMMFL_00197 1.9e-68 WQ51_03320 S Protein of unknown function (DUF1149)
FKIEMMFL_00198 8.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FKIEMMFL_00199 2.1e-181 yubA S AI-2E family transporter
FKIEMMFL_00200 4.6e-64 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
FKIEMMFL_00201 2.9e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
FKIEMMFL_00202 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
FKIEMMFL_00203 2.8e-22
FKIEMMFL_00204 8.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FKIEMMFL_00205 3.9e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FKIEMMFL_00206 3.1e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
FKIEMMFL_00207 3.3e-109 yjbK S CYTH
FKIEMMFL_00208 5.9e-112 yjbH Q Thioredoxin
FKIEMMFL_00209 4.4e-163 coiA 3.6.4.12 S Competence protein
FKIEMMFL_00210 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FKIEMMFL_00211 5e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FKIEMMFL_00212 2.1e-302 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FKIEMMFL_00213 1.2e-39 ptsH G phosphocarrier protein HPR
FKIEMMFL_00214 5.8e-10
FKIEMMFL_00215 0.0 clpE O Belongs to the ClpA ClpB family
FKIEMMFL_00216 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
FKIEMMFL_00217 4.3e-73 mco Q Multicopper oxidase
FKIEMMFL_00218 7.3e-209 mco Q Multicopper oxidase
FKIEMMFL_00219 5.4e-19
FKIEMMFL_00220 1.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FKIEMMFL_00221 1.2e-157 hlyX S Transporter associated domain
FKIEMMFL_00222 3.5e-74
FKIEMMFL_00223 4.5e-85
FKIEMMFL_00224 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
FKIEMMFL_00225 1.8e-243 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKIEMMFL_00226 1.1e-181 D Alpha beta
FKIEMMFL_00227 7.4e-19
FKIEMMFL_00228 4.6e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FKIEMMFL_00229 7.7e-166 yihY S Belongs to the UPF0761 family
FKIEMMFL_00230 3.6e-162 map 3.4.11.18 E Methionine Aminopeptidase
FKIEMMFL_00231 1.3e-78 fld C Flavodoxin
FKIEMMFL_00232 3.3e-51 gtcA S Teichoic acid glycosylation protein
FKIEMMFL_00233 5e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
FKIEMMFL_00234 2.3e-31
FKIEMMFL_00235 8.7e-181 E Amino acid permease
FKIEMMFL_00237 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
FKIEMMFL_00238 1.1e-228 ynbB 4.4.1.1 P aluminum resistance
FKIEMMFL_00239 1e-232 pyrP F Permease
FKIEMMFL_00240 4.2e-139 pfoS S Phosphotransferase system, EIIC
FKIEMMFL_00241 1.9e-31 pfoS S Phosphotransferase system, EIIC
FKIEMMFL_00243 9.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FKIEMMFL_00244 2.9e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
FKIEMMFL_00245 1e-122 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
FKIEMMFL_00246 6.4e-227 potE E amino acid
FKIEMMFL_00247 9.8e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
FKIEMMFL_00248 2.1e-249 yhdP S Transporter associated domain
FKIEMMFL_00249 2.9e-21 3.4.22.70 M Sortase family
FKIEMMFL_00251 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
FKIEMMFL_00252 2.4e-130 gntR K UbiC transcription regulator-associated domain protein
FKIEMMFL_00253 7.8e-174 rihB 3.2.2.1 F Nucleoside
FKIEMMFL_00254 6.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FKIEMMFL_00255 2e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
FKIEMMFL_00256 3.3e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKIEMMFL_00257 5.9e-88
FKIEMMFL_00258 9e-37
FKIEMMFL_00259 5.6e-10 S Protein of unknown function (DUF2974)
FKIEMMFL_00260 3.3e-269 S Uncharacterized protein conserved in bacteria (DUF2252)
FKIEMMFL_00261 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FKIEMMFL_00262 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
FKIEMMFL_00263 2.9e-148 glnH ET Bacterial periplasmic substrate-binding proteins
FKIEMMFL_00264 5.7e-110 glnP P ABC transporter permease
FKIEMMFL_00265 2.5e-110 gluC P ABC transporter permease
FKIEMMFL_00266 5.4e-150 glnH ET ABC transporter substrate-binding protein
FKIEMMFL_00267 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FKIEMMFL_00268 3.3e-118 udk 2.7.1.48 F Zeta toxin
FKIEMMFL_00269 3.7e-111 udk 2.7.1.48 F Zeta toxin
FKIEMMFL_00271 7.8e-100 S ABC-type cobalt transport system, permease component
FKIEMMFL_00272 7.8e-210 pepA E M42 glutamyl aminopeptidase
FKIEMMFL_00273 2.2e-281 pipD E Dipeptidase
FKIEMMFL_00274 1.7e-142 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FKIEMMFL_00275 5.5e-119 ybhL S Belongs to the BI1 family
FKIEMMFL_00276 3.3e-217 mdtG EGP Major facilitator Superfamily
FKIEMMFL_00277 2.6e-56
FKIEMMFL_00279 6.1e-49 kgtP EGP Sugar (and other) transporter
FKIEMMFL_00280 5.3e-100 kgtP EGP Sugar (and other) transporter
FKIEMMFL_00281 2.2e-309 ybiT S ABC transporter, ATP-binding protein
FKIEMMFL_00282 3.5e-166 mleP3 S Membrane transport protein
FKIEMMFL_00283 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FKIEMMFL_00284 6.2e-68 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
FKIEMMFL_00286 6.7e-51 mtlR K transcriptional antiterminator
FKIEMMFL_00287 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FKIEMMFL_00288 1.2e-85 K AsnC family
FKIEMMFL_00289 9e-17 ypaA S membrane
FKIEMMFL_00290 4.4e-26 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
FKIEMMFL_00292 2.5e-29 yliE T Putative diguanylate phosphodiesterase
FKIEMMFL_00293 9.3e-102 T Gaf domain
FKIEMMFL_00294 6.7e-95 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
FKIEMMFL_00295 9.9e-123 alkD L DNA alkylation repair enzyme
FKIEMMFL_00296 1.5e-239 brnQ U Component of the transport system for branched-chain amino acids
FKIEMMFL_00297 6.9e-57 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
FKIEMMFL_00298 3.3e-25 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
FKIEMMFL_00299 6.4e-47 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
FKIEMMFL_00300 2.1e-32 copZ P Heavy-metal-associated domain
FKIEMMFL_00301 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
FKIEMMFL_00302 1.1e-69 carB 6.3.5.5 C carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FKIEMMFL_00303 4.3e-44 carB 6.3.5.5 F Carbamoyl-phosphate synthase
FKIEMMFL_00304 1.2e-32 carB 6.3.5.5 F Carbamoyl-phosphate synthase
FKIEMMFL_00305 2.2e-119 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
FKIEMMFL_00306 3.7e-148 L Mrr N-terminal domain
FKIEMMFL_00307 4.8e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKIEMMFL_00308 1.4e-117 S Protein of unknown function (DUF1211)
FKIEMMFL_00309 1.5e-169 yegS 2.7.1.107 G Lipid kinase
FKIEMMFL_00310 3.5e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FKIEMMFL_00311 7.9e-266 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FKIEMMFL_00312 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FKIEMMFL_00313 9.2e-193 camS S sex pheromone
FKIEMMFL_00314 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKIEMMFL_00315 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
FKIEMMFL_00316 1.3e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
FKIEMMFL_00317 9.1e-102 S ECF transporter, substrate-specific component
FKIEMMFL_00319 1.8e-89 ydcK S Belongs to the SprT family
FKIEMMFL_00320 1.1e-107 V ABC transporter
FKIEMMFL_00321 2.9e-11
FKIEMMFL_00323 0.0 pacL 3.6.3.8 P P-type ATPase
FKIEMMFL_00324 3.3e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FKIEMMFL_00325 4.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
FKIEMMFL_00326 1e-204 csaB M Glycosyl transferases group 1
FKIEMMFL_00327 1.4e-133 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
FKIEMMFL_00328 1.7e-260 epsU S Polysaccharide biosynthesis protein
FKIEMMFL_00329 4.2e-222 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FKIEMMFL_00330 3.9e-125 gntR1 K UTRA
FKIEMMFL_00331 2.1e-199
FKIEMMFL_00332 2.4e-214
FKIEMMFL_00333 9e-67 oppA2 E ABC transporter, substratebinding protein
FKIEMMFL_00334 2.9e-101 oppA2 E ABC transporter, substratebinding protein
FKIEMMFL_00335 3.3e-10 oppA2 E ABC transporter, substratebinding protein
FKIEMMFL_00338 4.1e-163 pfoS S Phosphotransferase system, EIIC
FKIEMMFL_00339 3.2e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
FKIEMMFL_00342 1e-184 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
FKIEMMFL_00343 8.6e-119 dedA S SNARE-like domain protein
FKIEMMFL_00344 3.5e-106 S Protein of unknown function (DUF1461)
FKIEMMFL_00345 4.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FKIEMMFL_00346 1.9e-82 yutD S Protein of unknown function (DUF1027)
FKIEMMFL_00347 2.7e-279 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
FKIEMMFL_00348 5.6e-58
FKIEMMFL_00349 4.9e-182 ccpA K catabolite control protein A
FKIEMMFL_00350 5.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FKIEMMFL_00351 1.8e-41
FKIEMMFL_00352 5.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FKIEMMFL_00353 2.7e-149 ykuT M mechanosensitive ion channel
FKIEMMFL_00354 2.3e-113 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FKIEMMFL_00355 1.7e-66 yslB S Protein of unknown function (DUF2507)
FKIEMMFL_00356 2.7e-54 trxA O Belongs to the thioredoxin family
FKIEMMFL_00357 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FKIEMMFL_00358 1e-40 yrzB S Belongs to the UPF0473 family
FKIEMMFL_00359 1.8e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FKIEMMFL_00360 5.7e-42 yrzL S Belongs to the UPF0297 family
FKIEMMFL_00361 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKIEMMFL_00362 7.5e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FKIEMMFL_00363 4.1e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
FKIEMMFL_00364 6.4e-207 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FKIEMMFL_00365 2.9e-284 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FKIEMMFL_00366 2.7e-35 yajC U Preprotein translocase
FKIEMMFL_00367 1.6e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FKIEMMFL_00368 9.2e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FKIEMMFL_00369 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FKIEMMFL_00370 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FKIEMMFL_00371 1.3e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FKIEMMFL_00372 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FKIEMMFL_00373 1.3e-122 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FKIEMMFL_00374 2.1e-303 uup S ABC transporter, ATP-binding protein
FKIEMMFL_00375 7.6e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FKIEMMFL_00376 3.1e-95 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
FKIEMMFL_00377 1.2e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
FKIEMMFL_00378 6.8e-90 folT S ECF transporter, substrate-specific component
FKIEMMFL_00379 3.4e-89 folT S ECF transporter, substrate-specific component
FKIEMMFL_00380 2.1e-145 fat 3.1.2.21 I Acyl-ACP thioesterase
FKIEMMFL_00381 3.8e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FKIEMMFL_00382 9.9e-55 yabA L Involved in initiation control of chromosome replication
FKIEMMFL_00383 1.6e-160 holB 2.7.7.7 L DNA polymerase III
FKIEMMFL_00384 2.4e-53 yaaQ S Cyclic-di-AMP receptor
FKIEMMFL_00385 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FKIEMMFL_00386 1.4e-34 S Protein of unknown function (DUF2508)
FKIEMMFL_00387 1.5e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FKIEMMFL_00388 3.5e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FKIEMMFL_00389 1.6e-287 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FKIEMMFL_00390 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FKIEMMFL_00391 7.2e-112 rsmC 2.1.1.172 J Methyltransferase
FKIEMMFL_00392 1.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FKIEMMFL_00393 1.6e-172
FKIEMMFL_00394 3.3e-39
FKIEMMFL_00395 1.9e-14 L Helix-turn-helix domain
FKIEMMFL_00396 4.6e-205 pbpX1 V Beta-lactamase
FKIEMMFL_00397 9.7e-115 dnaD L DnaD domain protein
FKIEMMFL_00398 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FKIEMMFL_00399 6.8e-150 S Sucrose-6F-phosphate phosphohydrolase
FKIEMMFL_00400 2.1e-70 I Psort location Cytoplasmic, score
FKIEMMFL_00401 5.5e-54 I acetylesterase activity
FKIEMMFL_00402 2.4e-189 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKIEMMFL_00403 0.0 dap2 3.4.19.1 E Prolyl oligopeptidase family
FKIEMMFL_00404 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
FKIEMMFL_00405 2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FKIEMMFL_00406 3.2e-106 ypsA S Belongs to the UPF0398 family
FKIEMMFL_00407 1e-57 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FKIEMMFL_00408 8.7e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
FKIEMMFL_00409 4.5e-126 XK27_01810 S Calcineurin-like phosphoesterase
FKIEMMFL_00410 6e-58
FKIEMMFL_00411 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
FKIEMMFL_00412 9.3e-72 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FKIEMMFL_00413 1e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FKIEMMFL_00414 3.3e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FKIEMMFL_00415 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
FKIEMMFL_00416 5.6e-43 gcvR T Belongs to the UPF0237 family
FKIEMMFL_00417 2.9e-246 XK27_08635 S UPF0210 protein
FKIEMMFL_00418 1.1e-306 FbpA K Fibronectin-binding protein
FKIEMMFL_00419 6.3e-157 degV S EDD domain protein, DegV family
FKIEMMFL_00420 8.9e-182
FKIEMMFL_00421 1.3e-165 EG EamA-like transporter family
FKIEMMFL_00422 1.8e-119 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKIEMMFL_00423 3.1e-84 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKIEMMFL_00424 1.3e-111 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FKIEMMFL_00425 7.9e-59 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FKIEMMFL_00426 1.4e-115 3.1.3.73 G phosphoglycerate mutase
FKIEMMFL_00427 4.7e-13 XK27_06780 V ABC transporter permease
FKIEMMFL_00428 6e-91 C Nitroreductase family
FKIEMMFL_00429 1e-44 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FKIEMMFL_00430 1.5e-25 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FKIEMMFL_00432 3e-201 xerS L Belongs to the 'phage' integrase family
FKIEMMFL_00433 4.9e-210 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
FKIEMMFL_00434 2.9e-194 S Uncharacterized protein conserved in bacteria (DUF2325)
FKIEMMFL_00435 5.3e-72 S Sel1-like repeats.
FKIEMMFL_00436 2.2e-124 T Diguanylate cyclase, GGDEF domain
FKIEMMFL_00438 1.9e-20 S Domain of unknown function (DUF4343)
FKIEMMFL_00439 2.3e-92 GM NmrA-like family
FKIEMMFL_00440 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
FKIEMMFL_00441 1.3e-293 hsdM 2.1.1.72 V type I restriction-modification system
FKIEMMFL_00442 1e-141 3.1.21.3 V Type I restriction modification DNA specificity domain
FKIEMMFL_00443 3.2e-172 L Belongs to the 'phage' integrase family
FKIEMMFL_00444 1.4e-129 3.1.21.3 V Type I restriction modification DNA specificity domain
FKIEMMFL_00445 1.6e-33 lysR7 K LysR substrate binding domain
FKIEMMFL_00446 1.1e-84 L DDE superfamily endonuclease
FKIEMMFL_00448 5.5e-121 WQ51_05710 S Mitochondrial biogenesis AIM24
FKIEMMFL_00449 6.5e-263 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
FKIEMMFL_00450 1.2e-59 ypmB S Protein conserved in bacteria
FKIEMMFL_00451 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
FKIEMMFL_00452 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
FKIEMMFL_00453 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
FKIEMMFL_00454 8.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
FKIEMMFL_00455 2.3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
FKIEMMFL_00456 1.7e-201 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
FKIEMMFL_00457 1.8e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FKIEMMFL_00458 1.4e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
FKIEMMFL_00459 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FKIEMMFL_00460 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FKIEMMFL_00461 3.2e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FKIEMMFL_00462 7.6e-31 yfiC V ABC transporter
FKIEMMFL_00463 1.8e-184 yfiC V ABC transporter
FKIEMMFL_00464 2.8e-52 V abc transporter atp-binding protein
FKIEMMFL_00465 1e-41 V ABC transporter, ATP-binding protein
FKIEMMFL_00467 1.2e-43 lmrA V (ABC) transporter
FKIEMMFL_00468 1.2e-14 K Winged helix DNA-binding domain
FKIEMMFL_00469 2.1e-151 supH G Sucrose-6F-phosphate phosphohydrolase
FKIEMMFL_00470 9e-104
FKIEMMFL_00471 4.3e-155 2.7.7.65 T diguanylate cyclase
FKIEMMFL_00472 5e-290 yliE T Putative diguanylate phosphodiesterase
FKIEMMFL_00474 8.4e-103 2.7.7.65 T phosphorelay sensor kinase activity
FKIEMMFL_00475 7.8e-135 cbiQ P Cobalt transport protein
FKIEMMFL_00476 1.5e-149 P ABC transporter
FKIEMMFL_00477 4.2e-141 cbiO2 P ABC transporter
FKIEMMFL_00478 3.2e-43 S C4-dicarboxylate anaerobic carrier
FKIEMMFL_00479 8e-102 I NUDIX domain
FKIEMMFL_00480 7.6e-129 S Glycosyl hydrolases family 18
FKIEMMFL_00481 1.5e-46 S Glycosyl hydrolases family 18
FKIEMMFL_00482 7e-121 3.6.1.13 L NUDIX domain
FKIEMMFL_00484 6.1e-84 lsa S ABC transporter
FKIEMMFL_00485 2.1e-34 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
FKIEMMFL_00486 2.4e-21 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
FKIEMMFL_00487 1.2e-302 phoR 2.7.13.3 T Histidine kinase
FKIEMMFL_00488 1.4e-124 T Transcriptional regulatory protein, C terminal
FKIEMMFL_00489 1.8e-113 phoU P Plays a role in the regulation of phosphate uptake
FKIEMMFL_00490 3.2e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FKIEMMFL_00491 2.8e-157 pstA P Phosphate transport system permease protein PstA
FKIEMMFL_00492 1.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
FKIEMMFL_00493 9.1e-156 pstS P Phosphate
FKIEMMFL_00495 5e-15 yliE T GGDEF domain
FKIEMMFL_00496 6.9e-59 yliE T Putative diguanylate phosphodiesterase
FKIEMMFL_00497 2e-36
FKIEMMFL_00498 1.9e-13 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00499 4.7e-106 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00500 2.4e-30 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00501 3.7e-34 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00503 3.2e-172 glfT1 1.1.1.133 S Glycosyltransferase like family 2
FKIEMMFL_00504 5.6e-211 M Glycosyl transferases group 1
FKIEMMFL_00505 2.3e-147 M Domain of unknown function (DUF4422)
FKIEMMFL_00506 8.7e-08 wzy S EpsG family
FKIEMMFL_00507 1.6e-263 epsIIL S Membrane protein involved in the export of O-antigen and teichoic acid
FKIEMMFL_00508 2.4e-180 M LicD family
FKIEMMFL_00509 5.7e-85 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
FKIEMMFL_00510 3.2e-73 S Bacterial membrane protein, YfhO
FKIEMMFL_00512 8.1e-15 I transferase activity, transferring acyl groups other than amino-acyl groups
FKIEMMFL_00513 4.6e-79 S VanZ like family
FKIEMMFL_00514 2.7e-73 mesH S Teichoic acid glycosylation protein
FKIEMMFL_00515 2.2e-128 S VanZ like family
FKIEMMFL_00516 7.9e-42 sidC L DNA recombination
FKIEMMFL_00517 1.9e-107 L DNA recombination
FKIEMMFL_00518 1.3e-10 sidC L DNA recombination
FKIEMMFL_00519 0.0 3.1.4.46, 3.2.1.99 GH43 N domain, Protein
FKIEMMFL_00521 3.4e-134 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FKIEMMFL_00522 1.2e-123 pgm3 G Phosphoglycerate mutase family
FKIEMMFL_00523 6.4e-114 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
FKIEMMFL_00524 0.0 helD 3.6.4.12 L DNA helicase
FKIEMMFL_00525 1.4e-30 aatB ET ABC transporter substrate-binding protein
FKIEMMFL_00526 8.8e-72 aatB ET ABC transporter substrate-binding protein
FKIEMMFL_00527 1e-11 liaI S membrane
FKIEMMFL_00528 4.4e-74 XK27_02470 K LytTr DNA-binding domain
FKIEMMFL_00529 9.8e-103 E GDSL-like Lipase/Acylhydrolase
FKIEMMFL_00530 1e-170 coaA 2.7.1.33 F Pantothenic acid kinase
FKIEMMFL_00531 1.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FKIEMMFL_00532 1.6e-76 ymfM S Helix-turn-helix domain
FKIEMMFL_00533 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
FKIEMMFL_00534 1.2e-197
FKIEMMFL_00535 6.8e-71 L COG2826 Transposase and inactivated derivatives, IS30 family
FKIEMMFL_00536 1.9e-52 L transposase and inactivated derivatives, IS30 family
FKIEMMFL_00537 6.2e-288 V ABC transporter transmembrane region
FKIEMMFL_00538 6e-09 S PAS domain
FKIEMMFL_00539 8.6e-47 GK ROK family
FKIEMMFL_00540 1.9e-33 GK ROK family
FKIEMMFL_00542 1.7e-156 dkg S reductase
FKIEMMFL_00543 3e-124 endA F DNA RNA non-specific endonuclease
FKIEMMFL_00544 1e-41 E dipeptidase activity
FKIEMMFL_00545 4.4e-106
FKIEMMFL_00546 6e-85 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
FKIEMMFL_00547 4.6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
FKIEMMFL_00548 6.7e-154 corA P CorA-like Mg2+ transporter protein
FKIEMMFL_00549 1e-157 3.5.2.6 V Beta-lactamase enzyme family
FKIEMMFL_00550 3.3e-23
FKIEMMFL_00551 2.3e-99 yobS K Bacterial regulatory proteins, tetR family
FKIEMMFL_00552 0.0 ydgH S MMPL family
FKIEMMFL_00553 2.6e-176
FKIEMMFL_00554 8.4e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
FKIEMMFL_00555 9.2e-30 dedA 3.1.3.1 S SNARE associated Golgi protein
FKIEMMFL_00557 1.8e-84
FKIEMMFL_00558 8.4e-81 K GNAT family
FKIEMMFL_00559 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
FKIEMMFL_00560 1.5e-227 4.4.1.8 E Aminotransferase, class I
FKIEMMFL_00561 3.4e-166 htpX O Peptidase family M48
FKIEMMFL_00562 9.4e-93 1.6.5.2 GM NmrA-like family
FKIEMMFL_00563 9.3e-16 1.6.5.2 GM NAD(P)H-binding
FKIEMMFL_00564 3e-78 K Transcriptional regulator
FKIEMMFL_00565 2.3e-170 E ABC transporter, ATP-binding protein
FKIEMMFL_00566 3.2e-278 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FKIEMMFL_00567 2.3e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
FKIEMMFL_00568 2e-123 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
FKIEMMFL_00569 2.1e-137 prsW S Involved in the degradation of specific anti-sigma factors
FKIEMMFL_00570 8.9e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FKIEMMFL_00571 6.3e-25
FKIEMMFL_00572 4.2e-138
FKIEMMFL_00573 1.1e-173
FKIEMMFL_00574 2.8e-263 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
FKIEMMFL_00575 1.6e-157 3.4.17.13 V LD-carboxypeptidase
FKIEMMFL_00576 7.3e-14 S Fic/DOC family
FKIEMMFL_00577 3.1e-07 D Filamentation induced by cAMP protein fic
FKIEMMFL_00578 0.0 L Type III restriction enzyme, res subunit
FKIEMMFL_00579 9.9e-132 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
FKIEMMFL_00580 1.3e-107 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
FKIEMMFL_00581 1.7e-142 ydcF S Gram-negative-bacterium-type cell wall biogenesis
FKIEMMFL_00582 3.4e-106 yyaQ S YjbR
FKIEMMFL_00583 5.2e-147 ligA 2.7.7.7, 6.5.1.2 L EXOIII
FKIEMMFL_00584 9.3e-214 pbpX1 V Beta-lactamase
FKIEMMFL_00585 1.6e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FKIEMMFL_00586 3e-19 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
FKIEMMFL_00587 3.8e-11 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
FKIEMMFL_00589 2.5e-57 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
FKIEMMFL_00590 4e-27 P nitric oxide dioxygenase activity
FKIEMMFL_00591 1.5e-143 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00592 3.3e-86 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00593 1.8e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FKIEMMFL_00594 1.1e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FKIEMMFL_00595 3.1e-237 L Putative transposase DNA-binding domain
FKIEMMFL_00596 8.5e-69
FKIEMMFL_00597 3.5e-230 amtB P ammonium transporter
FKIEMMFL_00598 9.2e-189 S Glycosyl transferase family 2
FKIEMMFL_00599 2e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FKIEMMFL_00600 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FKIEMMFL_00601 5.2e-101 nusG K Participates in transcription elongation, termination and antitermination
FKIEMMFL_00602 1.8e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
FKIEMMFL_00603 1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FKIEMMFL_00604 1.5e-129 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FKIEMMFL_00605 2.4e-95 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FKIEMMFL_00606 1.3e-97 4.2.99.20 S Alpha/beta hydrolase family
FKIEMMFL_00607 1.8e-33
FKIEMMFL_00608 2.4e-101 yvrI K sigma factor activity
FKIEMMFL_00609 2.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKIEMMFL_00610 9.4e-77 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FKIEMMFL_00611 2.2e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
FKIEMMFL_00612 8.5e-107 F NUDIX domain
FKIEMMFL_00613 5.4e-161 K LysR substrate binding domain
FKIEMMFL_00614 7.2e-181 yeiH S Conserved hypothetical protein 698
FKIEMMFL_00615 3.3e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKIEMMFL_00617 5.7e-121 skfE V ATPases associated with a variety of cellular activities
FKIEMMFL_00618 8.7e-60 yvoA_1 K Transcriptional regulator, GntR family
FKIEMMFL_00620 1.4e-265 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
FKIEMMFL_00621 2.4e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
FKIEMMFL_00622 3.5e-71 K Transcriptional regulator
FKIEMMFL_00623 8.8e-47 GM epimerase
FKIEMMFL_00624 1.1e-19 S Protein of unknown function N-terminus (DUF3323)
FKIEMMFL_00627 0.0 yacH D Putative exonuclease SbcCD, C subunit
FKIEMMFL_00628 5.4e-57
FKIEMMFL_00629 2.9e-58 S transferase hexapeptide repeat
FKIEMMFL_00630 3.8e-93 S Hydrolases of the alpha beta superfamily
FKIEMMFL_00631 3.7e-43 ylbE GM NAD(P)H-binding
FKIEMMFL_00632 3.4e-61 ylbE GM NAD(P)H-binding
FKIEMMFL_00633 5.9e-46 V (ABC) transporter
FKIEMMFL_00634 4.1e-167 V Psort location CytoplasmicMembrane, score 10.00
FKIEMMFL_00635 5.4e-77 V Psort location CytoplasmicMembrane, score
FKIEMMFL_00636 1.7e-162 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKIEMMFL_00637 2.3e-78 K Transcriptional regulator, MarR family
FKIEMMFL_00638 1.7e-307 XK27_09600 V ABC transporter, ATP-binding protein
FKIEMMFL_00639 0.0 V ABC transporter transmembrane region
FKIEMMFL_00640 9.5e-52 P Rhodanese Homology Domain
FKIEMMFL_00641 3.9e-65 rnhA 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
FKIEMMFL_00642 5.7e-172 rnhA 3.1.26.4 L Resolvase, N-terminal
FKIEMMFL_00643 6.7e-47 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FKIEMMFL_00645 9.1e-43 yjdJ S GCN5-related N-acetyl-transferase
FKIEMMFL_00646 1.8e-133 gph 3.1.3.18 S HAD-hyrolase-like
FKIEMMFL_00647 2.4e-133 C FAD binding domain
FKIEMMFL_00648 6.1e-282 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00649 3.8e-93 3.6.1.13 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
FKIEMMFL_00650 1.1e-233 6.3.2.4 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FKIEMMFL_00651 1.1e-225 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
FKIEMMFL_00652 4.2e-158 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FKIEMMFL_00653 8.6e-201
FKIEMMFL_00654 4.6e-211 EGP Transmembrane secretion effector
FKIEMMFL_00655 4.6e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FKIEMMFL_00656 3.4e-73 2.7.13.3 T diguanylate cyclase
FKIEMMFL_00657 1.5e-20 5.99.1.2 T diguanylate cyclase
FKIEMMFL_00658 3.7e-16 5.99.1.2 T diguanylate cyclase
FKIEMMFL_00659 1.8e-110 T EAL domain
FKIEMMFL_00660 1.3e-11 5.99.1.2 T diguanylate cyclase
FKIEMMFL_00661 1.4e-84 S ECF-type riboflavin transporter, S component
FKIEMMFL_00662 3e-113 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
FKIEMMFL_00663 2.1e-111 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
FKIEMMFL_00664 3.3e-144 cbiQ P cobalt transport
FKIEMMFL_00665 0.0 ykoD P ABC transporter, ATP-binding protein
FKIEMMFL_00666 7.6e-100 S UPF0397 protein
FKIEMMFL_00667 7.6e-160 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
FKIEMMFL_00668 6.6e-254 cycA E Amino acid permease
FKIEMMFL_00669 0.0 S ABC-type transport system involved in multi-copper enzyme maturation permease component
FKIEMMFL_00670 9.6e-169 ytrB V ABC transporter
FKIEMMFL_00671 2.2e-58 ytrA K helix_turn_helix gluconate operon transcriptional repressor
FKIEMMFL_00675 3.7e-14 ybaJ Q Methyltransferase domain protein
FKIEMMFL_00676 2.3e-255 carB 6.3.5.5 F Psort location Cytoplasmic, score 8.87
FKIEMMFL_00677 1.7e-272 carB 6.3.5.5 F Psort location Cytoplasmic, score 8.87
FKIEMMFL_00678 8.2e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FKIEMMFL_00679 8.6e-37 T diguanylate cyclase activity
FKIEMMFL_00681 3.5e-34 V drug transmembrane transporter activity
FKIEMMFL_00682 1.7e-164 V MATE efflux family protein
FKIEMMFL_00683 6.1e-73 prpH 3.1.3.16 K 3.5.2 Transcription regulation
FKIEMMFL_00684 1.1e-73 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
FKIEMMFL_00685 1.2e-105 L Integrase
FKIEMMFL_00686 4.4e-75 cylB U ABC-2 type transporter
FKIEMMFL_00687 1e-13 cylB V ABC-2 type transporter
FKIEMMFL_00688 1.4e-72 S Psort location CytoplasmicMembrane, score
FKIEMMFL_00689 6e-76
FKIEMMFL_00690 4.5e-70 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
FKIEMMFL_00692 3.3e-130 cysA V ABC transporter, ATP-binding protein
FKIEMMFL_00693 0.0 V FtsX-like permease family
FKIEMMFL_00694 5.4e-13 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
FKIEMMFL_00695 7.3e-83 1.3.5.4 C FAD binding domain
FKIEMMFL_00696 1.8e-164 1.3.5.4 C FAD binding domain
FKIEMMFL_00697 2.6e-09 S Motility quorum-sensing regulator, toxin of MqsA
FKIEMMFL_00698 1.7e-104 ydaF J Acetyltransferase (GNAT) domain
FKIEMMFL_00699 7.5e-39 S SLAP domain
FKIEMMFL_00701 9.2e-73 cydD V abc transporter atp-binding protein
FKIEMMFL_00702 1.4e-275 sufB O assembly protein SufB
FKIEMMFL_00703 4.3e-74 nifU C SUF system FeS assembly protein, NifU family
FKIEMMFL_00704 4.3e-225 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FKIEMMFL_00705 4e-220 sufD O FeS assembly protein SufD
FKIEMMFL_00706 5.9e-143 sufC O FeS assembly ATPase SufC
FKIEMMFL_00707 6e-91 yjcF S Acetyltransferase (GNAT) domain
FKIEMMFL_00708 1.8e-84 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
FKIEMMFL_00709 5.3e-81
FKIEMMFL_00710 4.5e-20 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
FKIEMMFL_00712 4.9e-117 V ABC transporter, ATP-binding protein
FKIEMMFL_00713 1.9e-215 S FtsX-like permease family
FKIEMMFL_00716 8e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
FKIEMMFL_00717 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FKIEMMFL_00718 2.9e-29 secG U Preprotein translocase
FKIEMMFL_00719 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FKIEMMFL_00720 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FKIEMMFL_00721 2.2e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
FKIEMMFL_00722 5.8e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
FKIEMMFL_00725 2.5e-91 S Phosphatidylethanolamine-binding protein
FKIEMMFL_00726 1.3e-58 EGP Major facilitator Superfamily
FKIEMMFL_00727 1.6e-37 EGP Major facilitator Superfamily
FKIEMMFL_00728 4.3e-120 XK27_07525 3.6.1.55 F NUDIX domain
FKIEMMFL_00729 1.2e-12 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00730 3.4e-68 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00731 6.1e-142 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00732 1.6e-45
FKIEMMFL_00733 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
FKIEMMFL_00734 4.2e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FKIEMMFL_00735 6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FKIEMMFL_00736 3e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FKIEMMFL_00737 1.3e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FKIEMMFL_00738 1.6e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FKIEMMFL_00739 1.3e-61 rplQ J Ribosomal protein L17
FKIEMMFL_00740 5.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FKIEMMFL_00741 1.4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FKIEMMFL_00742 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FKIEMMFL_00743 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FKIEMMFL_00744 5.9e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FKIEMMFL_00745 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FKIEMMFL_00746 1.8e-72 rplO J Binds to the 23S rRNA
FKIEMMFL_00747 1.3e-24 rpmD J Ribosomal protein L30
FKIEMMFL_00748 1.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FKIEMMFL_00749 5.7e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FKIEMMFL_00750 2.8e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FKIEMMFL_00751 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FKIEMMFL_00752 9.3e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FKIEMMFL_00753 1e-32 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FKIEMMFL_00754 1.6e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FKIEMMFL_00755 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FKIEMMFL_00756 3.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
FKIEMMFL_00757 1.9e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FKIEMMFL_00758 9.4e-121 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FKIEMMFL_00759 8.9e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FKIEMMFL_00760 4.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FKIEMMFL_00761 2.8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FKIEMMFL_00762 8.3e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FKIEMMFL_00763 1.6e-106 rplD J Forms part of the polypeptide exit tunnel
FKIEMMFL_00764 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FKIEMMFL_00765 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
FKIEMMFL_00766 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKIEMMFL_00767 3.5e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FKIEMMFL_00768 1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FKIEMMFL_00769 9e-08 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
FKIEMMFL_00770 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FKIEMMFL_00771 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FKIEMMFL_00774 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
FKIEMMFL_00775 2.7e-82 yebR 1.8.4.14 T GAF domain-containing protein
FKIEMMFL_00779 3.7e-108 XK27_00160 S Domain of unknown function (DUF5052)
FKIEMMFL_00780 2.1e-213 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
FKIEMMFL_00781 4.1e-22 metY 2.5.1.49 E o-acetylhomoserine
FKIEMMFL_00783 2.3e-139 T diguanylate cyclase activity
FKIEMMFL_00785 2.5e-278 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
FKIEMMFL_00786 1.1e-197 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKIEMMFL_00787 2.9e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
FKIEMMFL_00788 4.7e-296 E ABC transporter, substratebinding protein
FKIEMMFL_00789 5.3e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FKIEMMFL_00790 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKIEMMFL_00791 7.8e-249 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FKIEMMFL_00792 2.2e-60 yabR J S1 RNA binding domain
FKIEMMFL_00793 1.5e-59 divIC D Septum formation initiator
FKIEMMFL_00794 3.2e-34 yabO J S4 domain protein
FKIEMMFL_00795 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FKIEMMFL_00796 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FKIEMMFL_00797 2e-126 S (CBS) domain
FKIEMMFL_00798 6.9e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FKIEMMFL_00799 9.4e-71 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FKIEMMFL_00800 8.2e-239 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FKIEMMFL_00801 2.7e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FKIEMMFL_00802 1.6e-41 rpmE2 J Ribosomal protein L31
FKIEMMFL_00803 1.3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FKIEMMFL_00804 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FKIEMMFL_00805 1.1e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FKIEMMFL_00806 2.5e-65 S Domain of unknown function (DUF1934)
FKIEMMFL_00807 1.4e-253 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
FKIEMMFL_00808 6.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FKIEMMFL_00809 1.3e-41
FKIEMMFL_00810 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FKIEMMFL_00811 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
FKIEMMFL_00812 6.4e-38 veg S Biofilm formation stimulator VEG
FKIEMMFL_00813 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FKIEMMFL_00814 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FKIEMMFL_00815 1.9e-149 tatD L hydrolase, TatD family
FKIEMMFL_00816 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKIEMMFL_00817 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
FKIEMMFL_00818 1.6e-103 S TPM domain
FKIEMMFL_00819 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
FKIEMMFL_00820 3.3e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
FKIEMMFL_00822 3e-119
FKIEMMFL_00823 2.2e-52 KLT Protein kinase domain
FKIEMMFL_00824 3.8e-128 V ATPases associated with a variety of cellular activities
FKIEMMFL_00825 1.9e-136 V ABC-2 type transporter
FKIEMMFL_00826 1.8e-113 E peptidase
FKIEMMFL_00828 6.6e-29 S Enterocin A Immunity
FKIEMMFL_00829 7.5e-146 2.7.7.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
FKIEMMFL_00830 2e-42 L Membrane
FKIEMMFL_00831 6.1e-102
FKIEMMFL_00832 1.3e-107 pncA Q Isochorismatase family
FKIEMMFL_00833 6e-132 L COG2826 Transposase and inactivated derivatives, IS30 family
FKIEMMFL_00834 6.5e-57 L Transposase and inactivated derivatives, IS30 family
FKIEMMFL_00835 2.7e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FKIEMMFL_00836 2.6e-80 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
FKIEMMFL_00837 6e-93 S Sucrose-6F-phosphate phosphohydrolase
FKIEMMFL_00838 4.6e-188 ansA 3.5.1.1 EJ L-asparaginase, type I
FKIEMMFL_00839 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
FKIEMMFL_00840 5.6e-52 ywhH S Aminoacyl-tRNA editing domain
FKIEMMFL_00841 1.7e-07 ywhH S Aminoacyl-tRNA editing domain
FKIEMMFL_00842 1.6e-174 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
FKIEMMFL_00843 2.8e-96 mmuP E amino acid
FKIEMMFL_00844 2.5e-64 mmuP E amino acid
FKIEMMFL_00845 8.9e-165 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
FKIEMMFL_00846 6.2e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
FKIEMMFL_00847 7.4e-130 2.4.2.3 F Phosphorylase superfamily
FKIEMMFL_00849 4.8e-126 tcyB E ABC transporter
FKIEMMFL_00850 2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FKIEMMFL_00851 3.8e-132 tcyA ET Belongs to the bacterial solute-binding protein 3 family
FKIEMMFL_00854 1.4e-243 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FKIEMMFL_00855 5.1e-113 K Transcriptional regulator
FKIEMMFL_00856 2.1e-283 V ABC-type multidrug transport system, ATPase and permease components
FKIEMMFL_00857 2.2e-290 KLT Protein kinase domain
FKIEMMFL_00858 5.8e-64 S HicB family
FKIEMMFL_00859 4.9e-38 S HicA toxin of bacterial toxin-antitoxin,
FKIEMMFL_00860 2.4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
FKIEMMFL_00861 1.2e-203 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FKIEMMFL_00862 5e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FKIEMMFL_00863 3.5e-225 pbuX F xanthine permease
FKIEMMFL_00864 2.6e-64
FKIEMMFL_00865 4.5e-252 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
FKIEMMFL_00866 3.1e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FKIEMMFL_00867 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FKIEMMFL_00868 2.1e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FKIEMMFL_00869 2.1e-73 hsp O Belongs to the small heat shock protein (HSP20) family
FKIEMMFL_00870 1.4e-258 pepC 3.4.22.40 E Papain family cysteine protease
FKIEMMFL_00871 5.1e-256 pepC 3.4.22.40 E aminopeptidase
FKIEMMFL_00872 2.8e-179 oppF P Belongs to the ABC transporter superfamily
FKIEMMFL_00873 3.9e-198 oppD P Belongs to the ABC transporter superfamily
FKIEMMFL_00874 7.8e-183 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKIEMMFL_00875 7.5e-145 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKIEMMFL_00876 5.6e-300 oppA E ABC transporter
FKIEMMFL_00877 3.6e-110 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00878 1.6e-123 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00879 1.9e-30 oppA E transmembrane transport
FKIEMMFL_00880 1.6e-291 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00881 1.2e-169 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00882 9.1e-62 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00883 4e-19 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00884 1.6e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
FKIEMMFL_00885 4.7e-243 N Uncharacterized conserved protein (DUF2075)
FKIEMMFL_00886 3.9e-193 mmuP E amino acid
FKIEMMFL_00887 1.2e-232 amd 3.5.1.47 E Peptidase family M20/M25/M40
FKIEMMFL_00888 1.7e-11 steT E amino acid
FKIEMMFL_00889 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
FKIEMMFL_00891 1.8e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FKIEMMFL_00894 5.9e-160 cjaA ET ABC transporter substrate-binding protein
FKIEMMFL_00895 3.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FKIEMMFL_00896 4e-79 P ABC transporter permease
FKIEMMFL_00897 6e-112 papP P ABC transporter, permease protein
FKIEMMFL_00898 2.8e-13 S Uncharacterized protein conserved in bacteria (DUF2255)
FKIEMMFL_00899 3.1e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
FKIEMMFL_00900 6.7e-201 folP 2.5.1.15 H dihydropteroate synthase
FKIEMMFL_00901 1.4e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FKIEMMFL_00902 2e-202 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
FKIEMMFL_00903 8.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FKIEMMFL_00904 2.8e-51 S Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
FKIEMMFL_00905 0.0 XK27_08315 M Sulfatase
FKIEMMFL_00906 2.9e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FKIEMMFL_00907 1.7e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FKIEMMFL_00908 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FKIEMMFL_00909 2e-132
FKIEMMFL_00910 1.9e-70 S Oxidoreductase
FKIEMMFL_00911 0.0 yjbQ P TrkA C-terminal domain protein
FKIEMMFL_00912 3.9e-258 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
FKIEMMFL_00913 5.7e-193 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FKIEMMFL_00914 4e-34 S Protein of unknown function (DUF2922)
FKIEMMFL_00915 1.3e-28
FKIEMMFL_00916 2.4e-85
FKIEMMFL_00917 1.7e-72
FKIEMMFL_00918 0.0 kup P Transport of potassium into the cell
FKIEMMFL_00919 0.0 pepO 3.4.24.71 O Peptidase family M13
FKIEMMFL_00920 5e-62 Z012_07300 O Glutaredoxin-related protein
FKIEMMFL_00921 2.1e-227 yttB EGP Major facilitator Superfamily
FKIEMMFL_00922 1.1e-36 XK27_04775 P Hemerythrin HHE cation binding domain protein
FKIEMMFL_00923 9.4e-33 S Iron-sulfur cluster assembly protein
FKIEMMFL_00924 8e-142 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FKIEMMFL_00925 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
FKIEMMFL_00926 7.6e-249 yxbA 6.3.1.12 S ATP-grasp enzyme
FKIEMMFL_00927 0.0 asnB 6.3.5.4 E Asparagine synthase
FKIEMMFL_00928 2e-274 S Calcineurin-like phosphoesterase
FKIEMMFL_00929 6.6e-84
FKIEMMFL_00931 1.8e-267 oppA E ABC transporter, substratebinding protein
FKIEMMFL_00932 1.1e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
FKIEMMFL_00933 2.6e-125 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
FKIEMMFL_00934 3.3e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FKIEMMFL_00935 4.3e-156 phnD P Phosphonate ABC transporter
FKIEMMFL_00936 2.5e-83 uspA T universal stress protein
FKIEMMFL_00937 1.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
FKIEMMFL_00938 5e-84 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
FKIEMMFL_00939 3e-89 ntd 2.4.2.6 F Nucleoside
FKIEMMFL_00940 1.2e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
FKIEMMFL_00941 0.0 G Belongs to the glycosyl hydrolase 31 family
FKIEMMFL_00942 2.7e-144 malG P ABC transporter permease
FKIEMMFL_00943 2.2e-102 malF P Binding-protein-dependent transport system inner membrane component
FKIEMMFL_00944 3.9e-85 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
FKIEMMFL_00945 1.4e-169 I alpha/beta hydrolase fold
FKIEMMFL_00946 4.5e-130 yibF S overlaps another CDS with the same product name
FKIEMMFL_00947 5.8e-184 yibE S overlaps another CDS with the same product name
FKIEMMFL_00948 6.7e-44
FKIEMMFL_00949 2.2e-204 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
FKIEMMFL_00950 1.5e-199 S Cysteine-rich secretory protein family
FKIEMMFL_00951 2.7e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
FKIEMMFL_00952 1.2e-144
FKIEMMFL_00953 3.4e-126 luxT K Bacterial regulatory proteins, tetR family
FKIEMMFL_00954 4.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FKIEMMFL_00955 2.8e-125 S Alpha/beta hydrolase family
FKIEMMFL_00956 2.5e-160 epsV 2.7.8.12 S glycosyl transferase family 2
FKIEMMFL_00957 1.8e-162 ypuA S Protein of unknown function (DUF1002)
FKIEMMFL_00958 1.5e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FKIEMMFL_00959 5.1e-181 S Alpha/beta hydrolase of unknown function (DUF915)
FKIEMMFL_00960 5.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKIEMMFL_00961 6.1e-82
FKIEMMFL_00962 1.9e-132 cobB K SIR2 family
FKIEMMFL_00963 3.7e-66 yeaO S Protein of unknown function, DUF488
FKIEMMFL_00964 9.4e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
FKIEMMFL_00965 2.3e-274 glnP P ABC transporter permease
FKIEMMFL_00966 3.5e-140 glnQ E ABC transporter, ATP-binding protein
FKIEMMFL_00967 5e-114 CBM50 M NlpC P60 family protein
FKIEMMFL_00968 4.5e-174 L HNH nucleases
FKIEMMFL_00969 2.8e-16
FKIEMMFL_00970 4.2e-192 ybiR P Citrate transporter
FKIEMMFL_00971 1.6e-94 lemA S LemA family
FKIEMMFL_00972 4.4e-150 htpX O Belongs to the peptidase M48B family
FKIEMMFL_00973 1.2e-152 mutR K Helix-turn-helix XRE-family like proteins
FKIEMMFL_00974 1.3e-221 S ATP diphosphatase activity
FKIEMMFL_00976 1.1e-136 S ABC-2 family transporter protein
FKIEMMFL_00977 1.6e-108 S ABC-2 family transporter protein
FKIEMMFL_00978 9.5e-172 natA1 S ABC transporter
FKIEMMFL_00979 1e-151 K helix_turn_helix, arabinose operon control protein
FKIEMMFL_00980 1.1e-270 emrY EGP Major facilitator Superfamily
FKIEMMFL_00981 1.6e-252 cbiO1 S ABC transporter, ATP-binding protein
FKIEMMFL_00982 3.2e-113 P Cobalt transport protein
FKIEMMFL_00983 1.8e-18 L transposase and inactivated derivatives, IS30 family
FKIEMMFL_00984 1.3e-36 L transposase and inactivated derivatives, IS30 family
FKIEMMFL_00985 2.7e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
FKIEMMFL_00990 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FKIEMMFL_00991 7.2e-162 htrA 3.4.21.107 O serine protease
FKIEMMFL_00992 8.8e-150 vicX 3.1.26.11 S domain protein
FKIEMMFL_00993 1.5e-141 yycI S YycH protein
FKIEMMFL_00994 5e-242 yycH S YycH protein
FKIEMMFL_00995 0.0 vicK 2.7.13.3 T Histidine kinase
FKIEMMFL_00996 7.5e-132 K response regulator
FKIEMMFL_00998 7.2e-149 arbV 2.3.1.51 I Acyl-transferase
FKIEMMFL_00999 3.2e-155 arbx M Glycosyl transferase family 8
FKIEMMFL_01000 2.9e-98 arbY M Glycosyl transferase family 8
FKIEMMFL_01001 1.2e-165 arbZ I Phosphate acyltransferases
FKIEMMFL_01002 0.0 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 C FAD binding domain
FKIEMMFL_01003 1.9e-172 K Transcriptional regulator, LysR family
FKIEMMFL_01004 1.6e-85 ydiN C succinate dehydrogenase
FKIEMMFL_01005 7.3e-53 ydiN EGP Major Facilitator Superfamily
FKIEMMFL_01006 2.2e-96 S Membrane
FKIEMMFL_01007 4.5e-222 naiP EGP Major facilitator Superfamily
FKIEMMFL_01008 2.4e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FKIEMMFL_01009 1.6e-171 glk 2.7.1.2 G Glucokinase
FKIEMMFL_01011 2e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
FKIEMMFL_01012 2.6e-166 cpsY K Transcriptional regulator, LysR family
FKIEMMFL_01013 1.2e-129
FKIEMMFL_01014 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FKIEMMFL_01015 5.3e-284 V ABC-type multidrug transport system, ATPase and permease components
FKIEMMFL_01016 5.2e-287 V ABC-type multidrug transport system, ATPase and permease components
FKIEMMFL_01017 3.4e-14 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
FKIEMMFL_01018 3e-41 L Transposase and inactivated derivatives, IS30 family
FKIEMMFL_01019 9.5e-132 L Transposase and inactivated derivatives, IS30 family
FKIEMMFL_01021 3.5e-31 bgl 3.2.1.21, 3.2.1.86 GT1 G beta-glucosidase activity
FKIEMMFL_01022 2e-193 manA 5.3.1.8 G mannose-6-phosphate isomerase
FKIEMMFL_01023 3.7e-28 scrK 2.7.1.2, 2.7.1.4 GK ROK family
FKIEMMFL_01025 3.5e-18 yliE T EAL domain
FKIEMMFL_01026 6e-140
FKIEMMFL_01027 1.6e-07
FKIEMMFL_01028 3.9e-84 K DNA-templated transcription, initiation
FKIEMMFL_01030 4.2e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
FKIEMMFL_01031 5.8e-163 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
FKIEMMFL_01032 0.0 S Bacterial membrane protein, YfhO
FKIEMMFL_01033 1.3e-179 yfdH GT2 M Glycosyltransferase like family 2
FKIEMMFL_01034 5.5e-92 racA K Domain of unknown function (DUF1836)
FKIEMMFL_01035 1.7e-145 yitS S EDD domain protein, DegV family
FKIEMMFL_01036 1.1e-103 T EAL domain
FKIEMMFL_01037 4.1e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
FKIEMMFL_01038 4.7e-125 gpmB G Phosphoglycerate mutase family
FKIEMMFL_01039 8.1e-13
FKIEMMFL_01040 1.1e-119
FKIEMMFL_01041 1.3e-42
FKIEMMFL_01042 1.2e-89 S biotin transmembrane transporter activity
FKIEMMFL_01043 1.6e-53 C Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
FKIEMMFL_01044 2.6e-43 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FKIEMMFL_01045 2.9e-182 gpsA 1.1.1.94 I Rossmann-like domain
FKIEMMFL_01046 3e-57 K sequence-specific DNA binding
FKIEMMFL_01047 2.2e-85
FKIEMMFL_01048 1.4e-70 F DNA/RNA non-specific endonuclease
FKIEMMFL_01050 8.1e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FKIEMMFL_01051 8.4e-66 S Core-2/I-Branching enzyme
FKIEMMFL_01052 3.6e-76 S Core-2/I-Branching enzyme
FKIEMMFL_01053 6.5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
FKIEMMFL_01054 2.2e-150 cps1D M Domain of unknown function (DUF4422)
FKIEMMFL_01055 8.6e-220 glf 5.4.99.9 M UDP-galactopyranose mutase
FKIEMMFL_01056 2.4e-109 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
FKIEMMFL_01057 2.3e-87 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
FKIEMMFL_01058 3e-11 N phage tail tape measure protein
FKIEMMFL_01059 6.1e-93 L the current gene model (or a revised gene model) may contain a frame shift
FKIEMMFL_01060 1.5e-29 L Transposase
FKIEMMFL_01061 4.9e-27
FKIEMMFL_01063 1.1e-154 XK27_00670 S ABC transporter
FKIEMMFL_01064 7.1e-96 S ABC transporter, ATP-binding protein
FKIEMMFL_01065 3.1e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
FKIEMMFL_01066 2.8e-18 higA K Helix-turn-helix XRE-family like proteins
FKIEMMFL_01068 2.9e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
FKIEMMFL_01069 2.9e-55 K Bacterial regulatory proteins, tetR family
FKIEMMFL_01070 2.1e-10
FKIEMMFL_01071 6.1e-28 L transposase activity
FKIEMMFL_01072 1.2e-120 S Membrane protein involved in the export of O-antigen and teichoic acid
FKIEMMFL_01073 9.8e-16 L Transposase
FKIEMMFL_01074 3.2e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
FKIEMMFL_01075 4.7e-94 S ECF transporter, substrate-specific component
FKIEMMFL_01076 3.2e-14 S Domain of unknown function (DUF4430)
FKIEMMFL_01077 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
FKIEMMFL_01078 6.7e-164 yvgN C Aldo keto reductase
FKIEMMFL_01079 4.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
FKIEMMFL_01080 2e-80
FKIEMMFL_01081 1e-161 xth 3.1.11.2 L exodeoxyribonuclease III
FKIEMMFL_01082 1.4e-59 S glycolate biosynthetic process
FKIEMMFL_01083 3.9e-18 L haloacid dehalogenase-like hydrolase
FKIEMMFL_01084 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
FKIEMMFL_01085 3.2e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FKIEMMFL_01086 6.1e-252 lysC 2.7.2.4 E Belongs to the aspartokinase family
FKIEMMFL_01087 1.7e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FKIEMMFL_01088 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FKIEMMFL_01089 4.7e-171 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKIEMMFL_01090 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FKIEMMFL_01091 2.8e-221 patA 2.6.1.1 E Aminotransferase
FKIEMMFL_01092 1.1e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FKIEMMFL_01093 9.5e-153
FKIEMMFL_01094 3.4e-67 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
FKIEMMFL_01095 7.5e-57 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
FKIEMMFL_01096 2.6e-160 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
FKIEMMFL_01097 4.8e-60 ppsA 2.7.9.2 G Pyruvate phosphate dikinase, PEP/pyruvate binding domain
FKIEMMFL_01098 1.2e-55 ppsA 2.7.9.2 G Belongs to the PEP-utilizing enzyme family
FKIEMMFL_01099 1.3e-293 ytgP S Polysaccharide biosynthesis protein
FKIEMMFL_01100 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
FKIEMMFL_01101 2.7e-152 S Protein of unknown function (DUF3298)
FKIEMMFL_01102 6.5e-99 K Sigma-70 region 2
FKIEMMFL_01103 5.9e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FKIEMMFL_01104 6.1e-93 J Acetyltransferase (GNAT) domain
FKIEMMFL_01105 4.4e-106 yjbF S SNARE associated Golgi protein
FKIEMMFL_01106 8.5e-153 I alpha/beta hydrolase fold
FKIEMMFL_01107 1.4e-156 hipB K Helix-turn-helix
FKIEMMFL_01108 8.6e-95 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
FKIEMMFL_01109 1.7e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
FKIEMMFL_01110 3e-18 L Transposase and inactivated derivatives, IS30 family
FKIEMMFL_01111 1.4e-107 galR K Transcriptional regulator
FKIEMMFL_01112 6.6e-26 K purine nucleotide biosynthetic process
FKIEMMFL_01113 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
FKIEMMFL_01114 0.0 lacS G Transporter
FKIEMMFL_01115 6e-188 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKIEMMFL_01116 9e-259 1.1.3.15 C FAD linked oxidases, C-terminal domain
FKIEMMFL_01117 4.2e-74 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
FKIEMMFL_01118 4.7e-136 metQ_4 P Belongs to the nlpA lipoprotein family
FKIEMMFL_01119 4.2e-91 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FKIEMMFL_01136 1.8e-230 E Arginine ornithine antiporter
FKIEMMFL_01137 2.1e-14 XK27_07210 6.1.1.6 S B3 4 domain
FKIEMMFL_01138 6.7e-209 S amidohydrolase
FKIEMMFL_01140 8.4e-216 EGP Major facilitator Superfamily
FKIEMMFL_01141 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
FKIEMMFL_01143 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
FKIEMMFL_01144 6.2e-308 S SH3-like domain
FKIEMMFL_01145 2.1e-53
FKIEMMFL_01146 1.8e-37
FKIEMMFL_01147 2.9e-79
FKIEMMFL_01148 1e-213 EGP Major Facilitator Superfamily
FKIEMMFL_01149 4.8e-41 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
FKIEMMFL_01150 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FKIEMMFL_01151 2.5e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FKIEMMFL_01152 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FKIEMMFL_01153 1.6e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
FKIEMMFL_01154 2.8e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FKIEMMFL_01155 5.2e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FKIEMMFL_01156 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FKIEMMFL_01157 6.6e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FKIEMMFL_01158 4.6e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
FKIEMMFL_01159 6.5e-110 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FKIEMMFL_01160 4.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
FKIEMMFL_01161 5.9e-241 purD 6.3.4.13 F Belongs to the GARS family
FKIEMMFL_01162 9.6e-56 livF E ABC transporter
FKIEMMFL_01163 3.6e-91 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
FKIEMMFL_01164 1.3e-65 arsC 1.20.4.1 P Belongs to the ArsC family
FKIEMMFL_01165 9.9e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
FKIEMMFL_01166 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
FKIEMMFL_01167 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FKIEMMFL_01168 2e-100 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FKIEMMFL_01169 8.1e-73 yqhY S Asp23 family, cell envelope-related function
FKIEMMFL_01170 1.8e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKIEMMFL_01171 4.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FKIEMMFL_01172 8e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FKIEMMFL_01173 1.7e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FKIEMMFL_01174 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FKIEMMFL_01175 7.8e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
FKIEMMFL_01176 7e-306 recN L May be involved in recombinational repair of damaged DNA
FKIEMMFL_01177 3.5e-46 oppA E transmembrane transport
FKIEMMFL_01178 2.9e-14 oppA E ABC transporter, substratebinding protein
FKIEMMFL_01179 3.2e-33 oppA E transmembrane transport
FKIEMMFL_01180 2.6e-49
FKIEMMFL_01181 1.1e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
FKIEMMFL_01182 2.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FKIEMMFL_01183 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FKIEMMFL_01184 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FKIEMMFL_01185 4.1e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FKIEMMFL_01186 4.3e-138 stp 3.1.3.16 T phosphatase
FKIEMMFL_01187 0.0 KLT serine threonine protein kinase
FKIEMMFL_01188 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FKIEMMFL_01189 4.7e-128 thiN 2.7.6.2 H thiamine pyrophosphokinase
FKIEMMFL_01191 1.8e-30 D nuclear chromosome segregation
FKIEMMFL_01194 6.5e-282 V ABC transporter transmembrane region
FKIEMMFL_01195 3.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
FKIEMMFL_01196 8.8e-57 asp S Asp23 family, cell envelope-related function
FKIEMMFL_01197 1.6e-278 yloV S DAK2 domain fusion protein YloV
FKIEMMFL_01198 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FKIEMMFL_01199 7.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FKIEMMFL_01200 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKIEMMFL_01201 3.7e-190 oppD P Belongs to the ABC transporter superfamily
FKIEMMFL_01202 2.4e-178 oppF P Belongs to the ABC transporter superfamily
FKIEMMFL_01203 7.7e-177 oppB P ABC transporter permease
FKIEMMFL_01204 1.3e-157 oppC P Binding-protein-dependent transport system inner membrane component
FKIEMMFL_01205 0.0 oppA1 E ABC transporter substrate-binding protein
FKIEMMFL_01206 0.0 oppA E ABC transporter substrate-binding protein
FKIEMMFL_01207 3.1e-127 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FKIEMMFL_01208 0.0 smc D Required for chromosome condensation and partitioning
FKIEMMFL_01209 3.4e-154 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FKIEMMFL_01210 1.5e-25 pipD E Dipeptidase
FKIEMMFL_01211 8.6e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FKIEMMFL_01212 1.2e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FKIEMMFL_01213 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
FKIEMMFL_01214 1.8e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FKIEMMFL_01215 5.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
FKIEMMFL_01216 1.8e-09 CP_1020 S Psort location Cytoplasmic, score 8.87
FKIEMMFL_01217 3.9e-09 snf 2.7.11.1 KL domain protein
FKIEMMFL_01218 0.0 snf 2.7.11.1 KL domain protein
FKIEMMFL_01219 5.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FKIEMMFL_01220 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
FKIEMMFL_01221 0.0 S TerB-C domain
FKIEMMFL_01222 5.2e-248 P P-loop Domain of unknown function (DUF2791)
FKIEMMFL_01223 0.0 lhr L DEAD DEAH box helicase
FKIEMMFL_01224 3.4e-97
FKIEMMFL_01225 9.5e-145 glnH ET ABC transporter substrate-binding protein
FKIEMMFL_01226 6e-149 glcU U ribose uptake protein RbsU
FKIEMMFL_01227 3.5e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FKIEMMFL_01228 1.5e-33 ynzC S UPF0291 protein
FKIEMMFL_01229 2.3e-31 yneF S Uncharacterised protein family (UPF0154)
FKIEMMFL_01230 0.0 mdlA V ABC transporter
FKIEMMFL_01231 0.0 mdlB V ABC transporter
FKIEMMFL_01232 2.6e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
FKIEMMFL_01233 1e-212 hom 1.1.1.3 E homoserine dehydrogenase
FKIEMMFL_01234 1.3e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
FKIEMMFL_01235 4.8e-182 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FKIEMMFL_01236 1.4e-115 plsC 2.3.1.51 I Acyltransferase
FKIEMMFL_01237 3.2e-189 yabB 2.1.1.223 L Methyltransferase small domain
FKIEMMFL_01238 1.1e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
FKIEMMFL_01239 5.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FKIEMMFL_01240 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
FKIEMMFL_01241 2.9e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FKIEMMFL_01242 7.6e-124 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FKIEMMFL_01243 1.1e-144 cdsA 2.7.7.41 S Belongs to the CDS family
FKIEMMFL_01244 2.3e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
FKIEMMFL_01245 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FKIEMMFL_01246 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FKIEMMFL_01247 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
FKIEMMFL_01248 6.8e-194 nusA K Participates in both transcription termination and antitermination
FKIEMMFL_01249 4.3e-43 ylxR K Protein of unknown function (DUF448)
FKIEMMFL_01250 4.8e-42 rplGA J ribosomal protein
FKIEMMFL_01251 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FKIEMMFL_01252 5.5e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FKIEMMFL_01253 1.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FKIEMMFL_01254 3.2e-53 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
FKIEMMFL_01255 7e-220 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FKIEMMFL_01256 3.9e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FKIEMMFL_01257 4.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FKIEMMFL_01258 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FKIEMMFL_01259 5.4e-26 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
FKIEMMFL_01265 1.1e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FKIEMMFL_01266 1.5e-261 mdr EGP Sugar (and other) transporter
FKIEMMFL_01267 7.8e-120 3.6.1.27 I Acid phosphatase homologues
FKIEMMFL_01268 5.4e-48 M Glycosyltransferase, group 2 family protein
FKIEMMFL_01269 7.6e-129 L DDE superfamily endonuclease
FKIEMMFL_01270 1.1e-39 M Glycosyltransferase like family 2
FKIEMMFL_01272 1.7e-54 L Putative transposase DNA-binding domain
FKIEMMFL_01273 3.2e-248 nhaC C Na H antiporter NhaC
FKIEMMFL_01274 1.2e-160 spoU 2.1.1.185 J Methyltransferase
FKIEMMFL_01275 7.4e-58 asnB 6.3.5.4 E Aluminium induced protein
FKIEMMFL_01276 1.1e-185 asnB 6.3.5.4 E Aluminium induced protein
FKIEMMFL_01284 8.1e-54 ribD 1.1.1.193, 3.5.4.26 H MafB19-like deaminase
FKIEMMFL_01285 1.7e-12 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
FKIEMMFL_01286 1.3e-199 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
FKIEMMFL_01287 1.4e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
FKIEMMFL_01288 1.1e-12
FKIEMMFL_01289 1.6e-232 isp2 L Transposase
FKIEMMFL_01290 2.1e-154 K LysR family
FKIEMMFL_01291 2.6e-37 P Sodium:sulfate symporter transmembrane region
FKIEMMFL_01292 1.8e-74
FKIEMMFL_01293 8.7e-65 cps4G M Glycosyl transferases group 1
FKIEMMFL_01294 6.2e-37 epsH S Hexapeptide repeat of succinyl-transferase
FKIEMMFL_01295 5.3e-174 M Glycosyl transferase 4-like
FKIEMMFL_01296 7.8e-123 rfbP M Bacterial sugar transferase
FKIEMMFL_01297 8.8e-147 ywqE 3.1.3.48 GM PHP domain protein
FKIEMMFL_01298 2e-106 ywqD 2.7.10.1 D Capsular exopolysaccharide family
FKIEMMFL_01299 1.9e-108 epsB M biosynthesis protein
FKIEMMFL_01300 4.9e-177 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FKIEMMFL_01301 4.9e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FKIEMMFL_01302 1e-118 M NlpC P60 family protein
FKIEMMFL_01303 5e-94 M NlpC P60 family protein
FKIEMMFL_01304 6.3e-38 M NlpC P60 family protein
FKIEMMFL_01305 2.5e-66 M NlpC P60 family protein
FKIEMMFL_01306 6.2e-108 M NlpC/P60 family
FKIEMMFL_01307 6.5e-76 M NlpC/P60 family
FKIEMMFL_01308 1.2e-199 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKIEMMFL_01309 6.2e-82 M NlpC P60 family
FKIEMMFL_01310 9.3e-95 gmk2 2.7.4.8 F Guanylate kinase homologues.
FKIEMMFL_01311 7.2e-45
FKIEMMFL_01312 3.7e-290 S O-antigen ligase like membrane protein
FKIEMMFL_01313 2.2e-111
FKIEMMFL_01314 1.4e-68
FKIEMMFL_01315 2.3e-84 S Threonine/Serine exporter, ThrE
FKIEMMFL_01316 7e-136 thrE S Putative threonine/serine exporter
FKIEMMFL_01317 9.5e-294 S ABC transporter, ATP-binding protein
FKIEMMFL_01318 2.7e-16
FKIEMMFL_01319 1.1e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FKIEMMFL_01320 2.4e-250 L Putative transposase DNA-binding domain
FKIEMMFL_01321 0.0 pepF E oligoendopeptidase F
FKIEMMFL_01322 2.4e-99 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
FKIEMMFL_01323 4.1e-48 KT response to antibiotic
FKIEMMFL_01324 8e-135 znuB U ABC 3 transport family
FKIEMMFL_01325 1e-119 fhuC P ABC transporter
FKIEMMFL_01326 1e-145 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
FKIEMMFL_01327 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
FKIEMMFL_01328 4.5e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
FKIEMMFL_01329 2.8e-134 fruR K DeoR C terminal sensor domain
FKIEMMFL_01330 1.4e-144 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
FKIEMMFL_01331 6.4e-298 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FKIEMMFL_01332 6.5e-221 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
FKIEMMFL_01333 1e-122 K response regulator
FKIEMMFL_01334 0.0 ndvA V ABC transporter
FKIEMMFL_01335 9.6e-311 V ABC transporter, ATP-binding protein
FKIEMMFL_01336 1.8e-136 XK27_01040 S Protein of unknown function (DUF1129)
FKIEMMFL_01337 6.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FKIEMMFL_01338 2.5e-45 yyzM S Bacterial protein of unknown function (DUF951)
FKIEMMFL_01339 7.8e-155 spo0J K Belongs to the ParB family
FKIEMMFL_01340 2.6e-138 soj D Sporulation initiation inhibitor
FKIEMMFL_01341 3.7e-143 noc K Belongs to the ParB family
FKIEMMFL_01342 7.4e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
FKIEMMFL_01343 1.2e-36 guaB2 L Resolvase, N terminal domain
FKIEMMFL_01344 3.9e-298 L Putative transposase DNA-binding domain
FKIEMMFL_01345 2.4e-87 cvpA S Colicin V production protein
FKIEMMFL_01346 6.8e-189 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
FKIEMMFL_01347 1.6e-143 3.1.3.48 T Tyrosine phosphatase family
FKIEMMFL_01348 5e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
FKIEMMFL_01349 3.8e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
FKIEMMFL_01350 1.5e-97 K WHG domain
FKIEMMFL_01351 1.5e-274 pipD E Dipeptidase
FKIEMMFL_01352 6.7e-17
FKIEMMFL_01353 2.1e-117 V AAA domain, putative AbiEii toxin, Type IV TA system
FKIEMMFL_01354 6.1e-109
FKIEMMFL_01356 6.6e-59 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
FKIEMMFL_01357 2.5e-18 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
FKIEMMFL_01358 6.4e-139 S Belongs to the UPF0246 family
FKIEMMFL_01359 6e-117
FKIEMMFL_01360 1.7e-226 S Putative peptidoglycan binding domain
FKIEMMFL_01361 8.3e-08 1.13.11.79 C Nitroreductase family
FKIEMMFL_01362 1.1e-29 drgA C coenzyme F420-1:gamma-L-glutamate ligase activity
FKIEMMFL_01363 0.0 pepN 3.4.11.2 E aminopeptidase
FKIEMMFL_01364 6.3e-36 lysM M LysM domain
FKIEMMFL_01365 1.8e-173 citR K Putative sugar-binding domain
FKIEMMFL_01366 2.4e-253 pipD M Peptidase family C69
FKIEMMFL_01367 8.6e-257 P Sodium:sulfate symporter transmembrane region
FKIEMMFL_01368 4.6e-263 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FKIEMMFL_01370 3.5e-150
FKIEMMFL_01371 1.7e-46 V RRXRR protein
FKIEMMFL_01372 1.4e-34
FKIEMMFL_01373 9.9e-91 ymdB S Macro domain protein
FKIEMMFL_01374 2e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
FKIEMMFL_01375 2.8e-288 V ABC-type multidrug transport system, ATPase and permease components
FKIEMMFL_01376 0.0 KLT serine threonine protein kinase
FKIEMMFL_01377 4e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
FKIEMMFL_01378 2.8e-220 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FKIEMMFL_01379 1.4e-129 cobQ S glutamine amidotransferase
FKIEMMFL_01380 1.5e-36
FKIEMMFL_01381 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
FKIEMMFL_01382 2.1e-128 5.99.1.2 T diguanylate cyclase
FKIEMMFL_01383 1.1e-22 brnQ U Component of the transport system for branched-chain amino acids
FKIEMMFL_01384 7.7e-31 brnQ U Component of the transport system for branched-chain amino acids
FKIEMMFL_01385 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
FKIEMMFL_01386 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FKIEMMFL_01387 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FKIEMMFL_01388 7.2e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FKIEMMFL_01389 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FKIEMMFL_01390 2.8e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FKIEMMFL_01391 8.2e-25 L Transposase
FKIEMMFL_01392 1.1e-31 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
FKIEMMFL_01393 5.7e-49 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
FKIEMMFL_01394 1.2e-158 yicL EG EamA-like transporter family
FKIEMMFL_01395 7.7e-140 puuD S peptidase C26
FKIEMMFL_01396 4.4e-149 S Sucrose-6F-phosphate phosphohydrolase
FKIEMMFL_01397 7.4e-166 S Alpha/beta hydrolase of unknown function (DUF915)
FKIEMMFL_01398 1e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FKIEMMFL_01399 5e-63 L Transposase
FKIEMMFL_01410 5.8e-137 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
FKIEMMFL_01417 3.6e-40 L DDE superfamily endonuclease
FKIEMMFL_01418 9.9e-100 sip L Belongs to the 'phage' integrase family
FKIEMMFL_01419 9e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
FKIEMMFL_01420 1.9e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FKIEMMFL_01421 5.7e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FKIEMMFL_01422 0.0 dnaK O Heat shock 70 kDa protein
FKIEMMFL_01423 6.8e-172 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FKIEMMFL_01424 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FKIEMMFL_01425 2.8e-123 srtA 3.4.22.70 M sortase family
FKIEMMFL_01426 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
FKIEMMFL_01427 9.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKIEMMFL_01428 2.5e-49 K DNA-binding transcription factor activity
FKIEMMFL_01429 6.5e-154 czcD P cation diffusion facilitator family transporter
FKIEMMFL_01430 5.3e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FKIEMMFL_01431 4.1e-185 S AI-2E family transporter
FKIEMMFL_01432 8e-15 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FKIEMMFL_01433 8.6e-68 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FKIEMMFL_01434 6e-28 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FKIEMMFL_01435 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
FKIEMMFL_01436 1.7e-159 lysR5 K LysR substrate binding domain
FKIEMMFL_01437 6.1e-261 glnPH2 P ABC transporter permease
FKIEMMFL_01438 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FKIEMMFL_01439 1.6e-103 S Protein of unknown function (DUF4230)
FKIEMMFL_01440 4.2e-181 yjgN S Bacterial protein of unknown function (DUF898)
FKIEMMFL_01441 1.8e-53 S Protein of unknown function (DUF2752)
FKIEMMFL_01442 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FKIEMMFL_01443 9.8e-152 yitS S Uncharacterised protein, DegV family COG1307
FKIEMMFL_01444 1.6e-100 3.6.1.27 I Acid phosphatase homologues
FKIEMMFL_01445 1.2e-157
FKIEMMFL_01446 3.7e-165 lysR7 K LysR substrate binding domain
FKIEMMFL_01447 4.1e-309 yfiB1 V ABC transporter, ATP-binding protein
FKIEMMFL_01448 0.0 XK27_10035 V ABC transporter
FKIEMMFL_01450 5.2e-08 yliE T Putative diguanylate phosphodiesterase
FKIEMMFL_01451 2.9e-26 yliE T Putative diguanylate phosphodiesterase
FKIEMMFL_01452 4.3e-169 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FKIEMMFL_01453 4.1e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FKIEMMFL_01454 1.6e-117 hlyIII S protein, hemolysin III
FKIEMMFL_01455 3.3e-155 DegV S Uncharacterised protein, DegV family COG1307
FKIEMMFL_01456 5.5e-36 yozE S Belongs to the UPF0346 family
FKIEMMFL_01457 7.4e-163 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FKIEMMFL_01458 1.7e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FKIEMMFL_01459 3.7e-151 dprA LU DNA protecting protein DprA
FKIEMMFL_01460 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FKIEMMFL_01461 4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FKIEMMFL_01462 1.8e-164 xerC D Phage integrase, N-terminal SAM-like domain
FKIEMMFL_01463 4e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FKIEMMFL_01464 1.2e-242 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FKIEMMFL_01465 1.8e-175 lacX 5.1.3.3 G Aldose 1-epimerase
FKIEMMFL_01468 2.9e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FKIEMMFL_01469 3.6e-224 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
FKIEMMFL_01470 1.2e-07 secY2 U SecY translocase
FKIEMMFL_01472 6.3e-56 L An automated process has identified a potential problem with this gene model
FKIEMMFL_01473 2.2e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FKIEMMFL_01475 8.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
FKIEMMFL_01476 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
FKIEMMFL_01477 6.3e-171 phoH T phosphate starvation-inducible protein PhoH
FKIEMMFL_01478 2.3e-98 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FKIEMMFL_01479 2.9e-75 cdd 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
FKIEMMFL_01480 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FKIEMMFL_01481 3.4e-135 recO L Involved in DNA repair and RecF pathway recombination
FKIEMMFL_01482 1.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
FKIEMMFL_01483 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
FKIEMMFL_01484 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FKIEMMFL_01485 1.7e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FKIEMMFL_01486 5.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FKIEMMFL_01487 1.4e-204 K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FKIEMMFL_01488 2.8e-37 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FKIEMMFL_01489 1.7e-41 celA 3.2.1.86 GT1 G beta-glucosidase activity
FKIEMMFL_01490 0.0 copB 3.6.3.4 P P-type ATPase
FKIEMMFL_01491 5e-35 mdt(A) EGP Major facilitator Superfamily
FKIEMMFL_01492 4.6e-200 2.1.1.72 V type I restriction-modification system
FKIEMMFL_01493 3.4e-25
FKIEMMFL_01494 8.4e-207 S Protein of unknown function DUF262
FKIEMMFL_01495 3.8e-41 N Uncharacterized conserved protein (DUF2075)
FKIEMMFL_01496 7.6e-201 N Uncharacterized conserved protein (DUF2075)
FKIEMMFL_01497 1.5e-65 L Transposase
FKIEMMFL_01498 8.2e-31 L Transposase
FKIEMMFL_01499 4.5e-111 prrC S AAA domain
FKIEMMFL_01500 5.4e-144 V HNH endonuclease
FKIEMMFL_01502 5.7e-47 vsr L DNA mismatch endonuclease Vsr
FKIEMMFL_01503 0.0 Z012_07420 3.1.21.5 V Z1 domain
FKIEMMFL_01504 5.2e-231 L NgoFVII restriction endonuclease
FKIEMMFL_01505 1.7e-218 2.1.1.37 H C-5 cytosine-specific DNA methylase
FKIEMMFL_01508 5.8e-46 K Transcriptional regulator
FKIEMMFL_01509 3.5e-65 1.3.5.4 C domain protein
FKIEMMFL_01510 8.9e-179 1.3.5.4 C FAD binding domain
FKIEMMFL_01511 4.9e-29 adaA1 2.1.1.63, 3.2.2.21 K sequence-specific DNA binding
FKIEMMFL_01512 7.7e-78 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FKIEMMFL_01513 8.9e-26 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FKIEMMFL_01514 3.6e-138 S Peptidase family M23
FKIEMMFL_01515 9e-80 mutT 3.6.1.55 F NUDIX domain
FKIEMMFL_01516 1.8e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
FKIEMMFL_01517 4.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FKIEMMFL_01518 4.3e-244 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
FKIEMMFL_01519 7.3e-23
FKIEMMFL_01520 2e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
FKIEMMFL_01521 1.5e-160 xerD L Phage integrase, N-terminal SAM-like domain
FKIEMMFL_01522 4.7e-48 S Alpha beta hydrolase
FKIEMMFL_01523 9.3e-72 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
FKIEMMFL_01524 5e-95 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
FKIEMMFL_01530 1.1e-149 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
FKIEMMFL_01531 1.6e-51 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
FKIEMMFL_01532 7.8e-143 G polysaccharide deacetylase
FKIEMMFL_01533 2.1e-17 G Polysaccharide deacetylase
FKIEMMFL_01536 4e-49 S Domain of Unknown Function with PDB structure (DUF3862)
FKIEMMFL_01538 2.6e-123 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FKIEMMFL_01539 1.8e-125 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
FKIEMMFL_01540 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
FKIEMMFL_01541 2.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FKIEMMFL_01542 3.1e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
FKIEMMFL_01543 1.9e-77 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FKIEMMFL_01544 1e-68 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FKIEMMFL_01545 3.9e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FKIEMMFL_01546 6.3e-123 IQ reductase
FKIEMMFL_01547 1.6e-179 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
FKIEMMFL_01548 1e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKIEMMFL_01549 8.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKIEMMFL_01550 4.3e-184 K AI-2E family transporter
FKIEMMFL_01551 0.0 S Predicted membrane protein (DUF2207)
FKIEMMFL_01552 5.4e-15
FKIEMMFL_01553 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
FKIEMMFL_01554 8.9e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
FKIEMMFL_01555 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FKIEMMFL_01556 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKIEMMFL_01557 4.2e-175 prmA J Ribosomal protein L11 methyltransferase
FKIEMMFL_01558 1.1e-89 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FKIEMMFL_01559 2e-226 yjjP S Putative threonine/serine exporter
FKIEMMFL_01560 4.8e-221 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
FKIEMMFL_01561 3.4e-217 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
FKIEMMFL_01562 1.2e-194 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
FKIEMMFL_01563 4.6e-51 S CRISPR-associated protein (Cas_Csn2)
FKIEMMFL_01564 4.6e-38 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FKIEMMFL_01565 2e-129 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FKIEMMFL_01566 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FKIEMMFL_01567 8.7e-18 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FKIEMMFL_01568 5.7e-228 sptS 2.7.13.3 T Histidine kinase
FKIEMMFL_01569 2.2e-117 K response regulator
FKIEMMFL_01570 7.8e-114 2.7.6.5 T Region found in RelA / SpoT proteins
FKIEMMFL_01571 6.2e-12 1.3.5.4 S FMN binding
FKIEMMFL_01573 3.8e-18
FKIEMMFL_01575 9.2e-183 argH 2.3.1.1, 4.3.2.1 E argininosuccinate lyase
FKIEMMFL_01577 7e-71
FKIEMMFL_01578 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKIEMMFL_01579 6.8e-09
FKIEMMFL_01580 3.4e-26
FKIEMMFL_01581 4.4e-115 K DNA-binding transcription factor activity
FKIEMMFL_01582 7.4e-09 K Transcriptional regulator, LysR family
FKIEMMFL_01583 4.7e-171 K LysR substrate binding domain
FKIEMMFL_01584 0.0 S Bacterial membrane protein YfhO
FKIEMMFL_01585 3.9e-229 S Tetratricopeptide repeat protein
FKIEMMFL_01586 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FKIEMMFL_01587 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
FKIEMMFL_01588 8.4e-213 rpsA 1.17.7.4 J Ribosomal protein S1
FKIEMMFL_01589 3e-108 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
FKIEMMFL_01591 3.9e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FKIEMMFL_01592 9.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FKIEMMFL_01593 5.9e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FKIEMMFL_01594 6e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FKIEMMFL_01595 8.9e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FKIEMMFL_01596 5.4e-164 xerD D recombinase XerD
FKIEMMFL_01597 4e-164 cvfB S S1 domain
FKIEMMFL_01598 4e-59 I Acyltransferase family
FKIEMMFL_01600 5.9e-39 ssuB P anion transmembrane transporter activity
FKIEMMFL_01601 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
FKIEMMFL_01602 2e-180 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FKIEMMFL_01603 0.0 dnaE 2.7.7.7 L DNA polymerase
FKIEMMFL_01604 4.3e-29 S Protein of unknown function (DUF2929)
FKIEMMFL_01605 4.8e-61 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FKIEMMFL_01606 4.4e-55 gmuR K UbiC transcription regulator-associated domain protein
FKIEMMFL_01607 1.9e-15 gmuR K UTRA
FKIEMMFL_01608 3.2e-98 ywlG S Belongs to the UPF0340 family
FKIEMMFL_01610 4.9e-34
FKIEMMFL_01611 0.0 L SNF2 family N-terminal domain
FKIEMMFL_01612 6.9e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
FKIEMMFL_01613 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
FKIEMMFL_01614 4.5e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FKIEMMFL_01615 3.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FKIEMMFL_01616 0.0 oatA I Acyltransferase
FKIEMMFL_01617 8.1e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FKIEMMFL_01618 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FKIEMMFL_01619 3.2e-183 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
FKIEMMFL_01620 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
FKIEMMFL_01621 8.5e-176 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKIEMMFL_01622 1.6e-108 S Amidohydrolase
FKIEMMFL_01623 3.1e-77 S Amidohydrolase
FKIEMMFL_01624 3.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FKIEMMFL_01625 1e-76 argR K Regulates arginine biosynthesis genes
FKIEMMFL_01626 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
FKIEMMFL_01627 2.8e-168 K LysR substrate binding domain
FKIEMMFL_01628 7.8e-227 EK Aminotransferase, class I
FKIEMMFL_01629 1.7e-69 E Methionine synthase
FKIEMMFL_01630 3.4e-26 L DDE superfamily endonuclease
FKIEMMFL_01632 1.2e-26 L DDE superfamily endonuclease
FKIEMMFL_01633 8.4e-10 L COG3547 Transposase and inactivated derivatives
FKIEMMFL_01634 8.5e-116 K Bacterial regulatory proteins, tetR family
FKIEMMFL_01635 0.0 yhcA V ABC transporter, ATP-binding protein
FKIEMMFL_01636 3.8e-66 S Iron-sulphur cluster biosynthesis
FKIEMMFL_01638 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FKIEMMFL_01639 2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FKIEMMFL_01640 1.3e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
FKIEMMFL_01641 2.9e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FKIEMMFL_01643 1.3e-45
FKIEMMFL_01644 1.3e-224 ywhK S Membrane
FKIEMMFL_01645 4.7e-85 ykuL S (CBS) domain
FKIEMMFL_01646 0.0 cadA P P-type ATPase
FKIEMMFL_01647 3.2e-201 napA P Sodium/hydrogen exchanger family
FKIEMMFL_01648 2.2e-122 S CAAX protease self-immunity
FKIEMMFL_01649 1.2e-200 S DUF218 domain
FKIEMMFL_01650 3e-193 tcsA S ABC transporter substrate-binding protein PnrA-like
FKIEMMFL_01652 1.4e-66 S Psort location Cytoplasmic, score
FKIEMMFL_01653 1.1e-187 KLT Protein tyrosine kinase
FKIEMMFL_01654 5.1e-70 S Domain of unknown function (DUF4352)
FKIEMMFL_01655 6.3e-191 tcsA S ABC transporter substrate-binding protein PnrA-like
FKIEMMFL_01656 2.3e-193 tcsA S ABC transporter substrate-binding protein PnrA-like
FKIEMMFL_01657 2.1e-285 xylG 3.6.3.17 S ABC transporter
FKIEMMFL_01658 1.8e-204 yufP S Belongs to the binding-protein-dependent transport system permease family
FKIEMMFL_01659 3.7e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
FKIEMMFL_01660 2.5e-21 EGP Major facilitator Superfamily
FKIEMMFL_01661 2.4e-158 yeaE S Aldo/keto reductase family
FKIEMMFL_01662 4.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FKIEMMFL_01664 1.2e-13 L PFAM Integrase catalytic region
FKIEMMFL_01666 5.5e-164 3.2.1.17 M peptidoglycan-binding domain-containing protein
FKIEMMFL_01667 2.9e-38
FKIEMMFL_01668 2.6e-123 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
FKIEMMFL_01669 2.2e-128 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
FKIEMMFL_01670 3.8e-268 glnP P ABC transporter
FKIEMMFL_01671 5.5e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FKIEMMFL_01672 3.7e-230 pbuG S permease
FKIEMMFL_01673 4.9e-282 clcA P chloride
FKIEMMFL_01674 1e-81 XK27_08850 S Aminoacyl-tRNA editing domain
FKIEMMFL_01675 5.4e-104
FKIEMMFL_01676 1.2e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FKIEMMFL_01677 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
FKIEMMFL_01678 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FKIEMMFL_01679 1.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FKIEMMFL_01680 4.9e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FKIEMMFL_01681 1.4e-62 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FKIEMMFL_01682 3e-243 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FKIEMMFL_01683 9e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FKIEMMFL_01684 2.2e-37 yaaA S S4 domain protein YaaA
FKIEMMFL_01685 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FKIEMMFL_01686 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FKIEMMFL_01687 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FKIEMMFL_01688 5.1e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
FKIEMMFL_01689 1.4e-88 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FKIEMMFL_01690 3.3e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FKIEMMFL_01691 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
FKIEMMFL_01692 4e-75 rplI J Binds to the 23S rRNA
FKIEMMFL_01693 5.7e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
FKIEMMFL_01694 8.1e-229 MA20_36090 S Protein of unknown function (DUF2974)
FKIEMMFL_01695 0.0 V ATPases associated with a variety of cellular activities
FKIEMMFL_01696 1.1e-68
FKIEMMFL_01698 1.5e-121 yhiD S MgtC family
FKIEMMFL_01700 1.2e-12 L transposase and inactivated derivatives, IS30 family
FKIEMMFL_01701 1.2e-146 L the current gene model (or a revised gene model) may contain a frame shift
FKIEMMFL_01702 3.4e-59 V ABC-type multidrug transport system, ATPase and permease components
FKIEMMFL_01703 1.4e-139 V ABC-type multidrug transport system, ATPase and permease components
FKIEMMFL_01705 2e-112 ybbL S ABC transporter, ATP-binding protein
FKIEMMFL_01706 3.3e-130 ybbM S Uncharacterised protein family (UPF0014)
FKIEMMFL_01707 1.7e-11
FKIEMMFL_01708 1.7e-247 lysA2 M Glycosyl hydrolases family 25
FKIEMMFL_01709 9.4e-11 K Acetyltransferase (GNAT) domain
FKIEMMFL_01710 9.5e-29 K Acetyltransferase (GNAT) domain
FKIEMMFL_01711 1.8e-153 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
FKIEMMFL_01712 2.9e-91 S ECF-type riboflavin transporter, S component
FKIEMMFL_01713 0.0 L Helicase C-terminal domain protein
FKIEMMFL_01714 8.2e-99 T integral membrane protein
FKIEMMFL_01715 1.9e-83 S YcxB-like protein
FKIEMMFL_01716 9.7e-68 K Transcriptional regulator
FKIEMMFL_01717 2.8e-32 qorB 1.6.5.2 GM epimerase
FKIEMMFL_01718 9.5e-57 qorB 1.6.5.2 GM NmrA-like family
FKIEMMFL_01719 1.3e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
FKIEMMFL_01721 1.4e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FKIEMMFL_01722 4e-73 L DDE superfamily endonuclease
FKIEMMFL_01723 3.3e-23 L Transposase
FKIEMMFL_01724 2.6e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
FKIEMMFL_01725 3.4e-203 pepO 3.4.24.71 O Peptidase family M13
FKIEMMFL_01726 1.5e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FKIEMMFL_01727 7.7e-58
FKIEMMFL_01728 1.2e-64 S Domain of unknown function DUF1828
FKIEMMFL_01729 3.3e-217 EGP Major facilitator Superfamily
FKIEMMFL_01730 2.8e-257 glnA 6.3.1.2 E glutamine synthetase
FKIEMMFL_01731 8.2e-78 ynbB 4.4.1.1 P aluminum resistance
FKIEMMFL_01732 1e-107 ynbB 4.4.1.1 P aluminum resistance
FKIEMMFL_01733 5.2e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FKIEMMFL_01734 2.6e-70 yqhL P Rhodanese-like protein
FKIEMMFL_01735 8.2e-32 yqgQ S Bacterial protein of unknown function (DUF910)
FKIEMMFL_01736 5.9e-115 gluP 3.4.21.105 S Rhomboid family
FKIEMMFL_01737 2.1e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FKIEMMFL_01738 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FKIEMMFL_01739 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
FKIEMMFL_01740 0.0 S membrane
FKIEMMFL_01741 5.3e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FKIEMMFL_01742 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FKIEMMFL_01743 1.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FKIEMMFL_01744 7.5e-61 yodB K Transcriptional regulator, HxlR family
FKIEMMFL_01745 4.9e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKIEMMFL_01746 5.8e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
FKIEMMFL_01747 1.7e-155 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FKIEMMFL_01748 3e-290 arlS 2.7.13.3 T Histidine kinase
FKIEMMFL_01749 2.9e-128 K response regulator
FKIEMMFL_01750 3.5e-100 yceD S Uncharacterized ACR, COG1399
FKIEMMFL_01751 1.9e-214 ylbM S Belongs to the UPF0348 family
FKIEMMFL_01752 1.2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FKIEMMFL_01753 5.6e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
FKIEMMFL_01754 2.9e-119 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FKIEMMFL_01755 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
FKIEMMFL_01756 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FKIEMMFL_01757 1.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
FKIEMMFL_01758 2.6e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FKIEMMFL_01759 4.1e-74 L Putative transposase DNA-binding domain
FKIEMMFL_01760 8.1e-185 L Putative transposase DNA-binding domain
FKIEMMFL_01761 5.4e-113 guaB2 L Resolvase, N terminal domain
FKIEMMFL_01762 4.5e-274 S Archaea bacterial proteins of unknown function
FKIEMMFL_01763 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FKIEMMFL_01764 1.5e-169 dnaI L Primosomal protein DnaI
FKIEMMFL_01765 4.4e-247 dnaB L Replication initiation and membrane attachment
FKIEMMFL_01766 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FKIEMMFL_01767 2.5e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FKIEMMFL_01768 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FKIEMMFL_01769 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKIEMMFL_01770 3.5e-39 EGP Major facilitator Superfamily
FKIEMMFL_01771 1.1e-113 EGP Major facilitator Superfamily
FKIEMMFL_01772 1.5e-13 EGP Major facilitator Superfamily
FKIEMMFL_01774 1.6e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
FKIEMMFL_01775 2.6e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FKIEMMFL_01776 1.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FKIEMMFL_01777 5.2e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FKIEMMFL_01778 3.3e-217 ecsB U ABC transporter
FKIEMMFL_01779 2e-135 ecsA V ABC transporter, ATP-binding protein
FKIEMMFL_01780 2.2e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
FKIEMMFL_01781 8e-55
FKIEMMFL_01782 2.3e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FKIEMMFL_01783 1.2e-132 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FKIEMMFL_01784 2.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FKIEMMFL_01785 1.1e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FKIEMMFL_01786 1.7e-51 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FKIEMMFL_01787 3.3e-67 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F shikimate kinase activity
FKIEMMFL_01788 1.1e-178 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
FKIEMMFL_01789 0.0 L AAA domain
FKIEMMFL_01790 8.7e-226 yhaO L Ser Thr phosphatase family protein
FKIEMMFL_01791 8.1e-55 yheA S Belongs to the UPF0342 family
FKIEMMFL_01792 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FKIEMMFL_01793 5.3e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FKIEMMFL_01794 3.9e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
FKIEMMFL_01795 4.5e-97 M ErfK YbiS YcfS YnhG
FKIEMMFL_01796 5e-57 3.4.22.70 M Sortase family
FKIEMMFL_01797 5.6e-57
FKIEMMFL_01798 3.7e-75 L Putative transposase DNA-binding domain
FKIEMMFL_01799 1.4e-11 L Putative transposase DNA-binding domain
FKIEMMFL_01801 5.7e-230 M ErfK YbiS YcfS YnhG
FKIEMMFL_01802 5.6e-158 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FKIEMMFL_01803 2.1e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
FKIEMMFL_01805 1e-90 1.2.3.3, 3.7.1.22 EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
FKIEMMFL_01806 1.2e-48 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
FKIEMMFL_01807 4e-147 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
FKIEMMFL_01809 8.4e-10 L COG3547 Transposase and inactivated derivatives
FKIEMMFL_01810 8e-151 yliE T Putative diguanylate phosphodiesterase
FKIEMMFL_01811 1.2e-64 yliE T domain protein
FKIEMMFL_01812 9e-186 arbY M Glycosyl transferase family 8
FKIEMMFL_01813 6.6e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FKIEMMFL_01814 3.4e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
FKIEMMFL_01815 5.4e-49
FKIEMMFL_01816 3.6e-265 pepC 3.4.22.40 E Peptidase C1-like family
FKIEMMFL_01818 2.4e-183 S AAA domain
FKIEMMFL_01819 2.1e-79 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FKIEMMFL_01820 1.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FKIEMMFL_01821 5.2e-29
FKIEMMFL_01822 2.6e-28
FKIEMMFL_01823 4.7e-128 pgm3 G Belongs to the phosphoglycerate mutase family
FKIEMMFL_01824 4.8e-118 S membrane transporter protein
FKIEMMFL_01825 2.3e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
FKIEMMFL_01826 1.5e-94 wecD K Acetyltransferase (GNAT) family
FKIEMMFL_01827 4.8e-196 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FKIEMMFL_01828 8.8e-09 3.5.2.6 V Beta-lactamase
FKIEMMFL_01829 7.3e-103 3.5.2.6 V Beta-lactamase
FKIEMMFL_01830 1.1e-136 ybbH_2 K Helix-turn-helix domain, rpiR family
FKIEMMFL_01831 1.1e-275 pepV 3.5.1.18 E dipeptidase PepV
FKIEMMFL_01832 1.5e-46 cycA E Amino acid permease
FKIEMMFL_01833 3.7e-166 cycA E Amino acid permease
FKIEMMFL_01834 3.4e-08 lacR K DeoR C terminal sensor domain
FKIEMMFL_01835 8e-252 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
FKIEMMFL_01836 2.8e-96 D nuclear chromosome segregation
FKIEMMFL_01837 1.8e-35 D nuclear chromosome segregation
FKIEMMFL_01838 6e-83 M LysM domain protein
FKIEMMFL_01842 7.2e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FKIEMMFL_01843 4.3e-283 thrC 4.2.3.1 E Threonine synthase
FKIEMMFL_01847 7.2e-100 K Acetyltransferase (GNAT) domain
FKIEMMFL_01848 1.5e-106 yiiE S Protein of unknown function (DUF1211)
FKIEMMFL_01849 7.7e-25
FKIEMMFL_01850 2.4e-95 scrR K Transcriptional regulator, LacI family
FKIEMMFL_01851 5.1e-111 scrB 3.2.1.26 GH32 G invertase
FKIEMMFL_01852 2.7e-51 scrB 3.2.1.26 GH32 G invertase
FKIEMMFL_01853 7.8e-79 2.7.1.199, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
FKIEMMFL_01854 1.9e-200 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FKIEMMFL_01855 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
FKIEMMFL_01856 8.9e-238 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
FKIEMMFL_01857 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
FKIEMMFL_01858 2.9e-276 E Amino acid permease
FKIEMMFL_01859 1.8e-53 L Transposase and inactivated derivatives, IS30 family
FKIEMMFL_01860 1.6e-198 G Major Facilitator Superfamily
FKIEMMFL_01861 3.6e-204 L COG2826 Transposase and inactivated derivatives, IS30 family
FKIEMMFL_01863 2.2e-72 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
FKIEMMFL_01864 3.8e-112 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
FKIEMMFL_01865 2.3e-13 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
FKIEMMFL_01866 3e-221 oxlT P Major Facilitator Superfamily
FKIEMMFL_01868 1.3e-18 K sequence-specific DNA binding
FKIEMMFL_01869 2.4e-47
FKIEMMFL_01870 0.0 recQ1 L Helicase conserved C-terminal domain
FKIEMMFL_01871 1.6e-188 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
FKIEMMFL_01872 9.6e-08 K Helix-turn-helix domain
FKIEMMFL_01874 2.1e-162 3.5.2.6 M NlpC/P60 family
FKIEMMFL_01875 4.5e-247 cycA E Amino acid permease
FKIEMMFL_01877 8.1e-63 manO S Domain of unknown function (DUF956)
FKIEMMFL_01878 2.4e-167 manN G system, mannose fructose sorbose family IID component
FKIEMMFL_01879 5.4e-139 manY G PTS system
FKIEMMFL_01880 3e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
FKIEMMFL_01881 3.8e-42 L DDE superfamily endonuclease
FKIEMMFL_01882 2.1e-22 L DDE superfamily endonuclease
FKIEMMFL_01883 1.8e-107 L DDE superfamily endonuclease
FKIEMMFL_01884 6.1e-88 L COG3547 Transposase and inactivated derivatives
FKIEMMFL_01885 8.4e-10 L COG3547 Transposase and inactivated derivatives

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)