ORF_ID e_value Gene_name EC_number CAZy COGs Description
KPLABODI_00001 9.1e-261 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KPLABODI_00002 6.3e-51 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KPLABODI_00003 6.4e-265 frdC 1.3.5.4 C FAD binding domain
KPLABODI_00004 3.4e-113 metI P ABC transporter permease
KPLABODI_00005 5.3e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KPLABODI_00006 3.2e-121 metQ2 P Belongs to the nlpA lipoprotein family
KPLABODI_00007 0.0 aha1 P E1-E2 ATPase
KPLABODI_00008 1.9e-38 aha1 P E1-E2 ATPase
KPLABODI_00009 9e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPLABODI_00010 1.8e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KPLABODI_00011 2.9e-122 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KPLABODI_00012 5.4e-65
KPLABODI_00013 0.0 E ABC transporter, substratebinding protein
KPLABODI_00015 2.8e-125 pnb C nitroreductase
KPLABODI_00017 3.3e-191 I Protein of unknown function (DUF2974)
KPLABODI_00018 4.4e-44 S Protein of unknown function (DUF2974)
KPLABODI_00019 1.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
KPLABODI_00020 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KPLABODI_00021 1.1e-194 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KPLABODI_00022 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPLABODI_00023 4.5e-149
KPLABODI_00024 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPLABODI_00025 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KPLABODI_00026 1.6e-33 rpsT J Binds directly to 16S ribosomal RNA
KPLABODI_00027 1.6e-180 holA 2.7.7.7 L DNA polymerase III delta subunit
KPLABODI_00028 0.0 comEC S Competence protein ComEC
KPLABODI_00029 6.4e-70 comEA L Competence protein ComEA
KPLABODI_00030 2.3e-190 ylbL T Belongs to the peptidase S16 family
KPLABODI_00031 9.8e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPLABODI_00032 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KPLABODI_00033 1.1e-53 ylbG S UPF0298 protein
KPLABODI_00034 7.1e-212 ftsW D Belongs to the SEDS family
KPLABODI_00035 0.0 typA T GTP-binding protein TypA
KPLABODI_00036 4.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPLABODI_00037 2.7e-35 ykzG S Belongs to the UPF0356 family
KPLABODI_00038 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPLABODI_00039 5.1e-251 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KPLABODI_00040 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KPLABODI_00041 1e-103 S Repeat protein
KPLABODI_00042 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KPLABODI_00043 2.1e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KPLABODI_00044 3.2e-56 XK27_04120 S Putative amino acid metabolism
KPLABODI_00045 2.8e-213 iscS 2.8.1.7 E Aminotransferase class V
KPLABODI_00046 3.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPLABODI_00047 5.4e-19
KPLABODI_00048 1.1e-101 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KPLABODI_00049 1.5e-32 cspA K 'Cold-shock' DNA-binding domain
KPLABODI_00050 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KPLABODI_00051 8.5e-145 ylmH S S4 domain protein
KPLABODI_00052 7.6e-46 yggT S YGGT family
KPLABODI_00053 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KPLABODI_00054 8.6e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KPLABODI_00055 2.2e-241 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KPLABODI_00056 1.1e-147 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KPLABODI_00057 1.2e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPLABODI_00058 5.6e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KPLABODI_00059 2.7e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPLABODI_00060 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KPLABODI_00061 4.8e-55 ftsL D Cell division protein FtsL
KPLABODI_00062 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KPLABODI_00063 4.1e-77 mraZ K Belongs to the MraZ family
KPLABODI_00064 5.7e-55 S Protein of unknown function (DUF3397)
KPLABODI_00066 1.4e-95 mreD
KPLABODI_00067 1.8e-137 mreC M Involved in formation and maintenance of cell shape
KPLABODI_00068 2.6e-175 mreB D cell shape determining protein MreB
KPLABODI_00069 2.7e-114 radC L DNA repair protein
KPLABODI_00070 6.8e-127 S Haloacid dehalogenase-like hydrolase
KPLABODI_00071 1.2e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KPLABODI_00072 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KPLABODI_00073 7.8e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPLABODI_00074 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPLABODI_00075 1.4e-217 iscS2 2.8.1.7 E Aminotransferase class V
KPLABODI_00076 3.4e-300 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPLABODI_00077 1.2e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPLABODI_00078 3.5e-82 yueI S Protein of unknown function (DUF1694)
KPLABODI_00079 3.6e-241 rarA L recombination factor protein RarA
KPLABODI_00080 1.3e-42
KPLABODI_00081 3e-78 usp6 T universal stress protein
KPLABODI_00082 2.7e-219 rodA D Belongs to the SEDS family
KPLABODI_00083 1.7e-34 S Protein of unknown function (DUF2969)
KPLABODI_00084 7.4e-48 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KPLABODI_00085 6.1e-177 mbl D Cell shape determining protein MreB Mrl
KPLABODI_00086 5.1e-32 ywzB S Protein of unknown function (DUF1146)
KPLABODI_00087 1.6e-73 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KPLABODI_00088 1.3e-247 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPLABODI_00089 2.4e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPLABODI_00090 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPLABODI_00091 3.9e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPLABODI_00092 4.2e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPLABODI_00093 3.1e-28 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPLABODI_00094 4.2e-127 atpB C it plays a direct role in the translocation of protons across the membrane
KPLABODI_00095 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KPLABODI_00096 5.4e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KPLABODI_00097 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KPLABODI_00098 2.1e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPLABODI_00099 1.4e-112 tdk 2.7.1.21 F thymidine kinase
KPLABODI_00100 7.9e-260 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KPLABODI_00101 4.3e-34
KPLABODI_00102 7.6e-191 ampC V Beta-lactamase
KPLABODI_00105 9.4e-178 oppA E ABC transporter, substratebinding protein
KPLABODI_00106 1.4e-23 oppA E ABC transporter, substratebinding protein
KPLABODI_00107 6.2e-257 pgi 5.3.1.9 G Belongs to the GPI family
KPLABODI_00108 3.1e-107 vanZ V VanZ like family
KPLABODI_00109 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KPLABODI_00110 2e-275 T PhoQ Sensor
KPLABODI_00111 6.1e-134 K Transcriptional regulatory protein, C terminal
KPLABODI_00113 1.5e-47
KPLABODI_00114 6.6e-88 lysA2 M Glycosyl hydrolases family 25
KPLABODI_00115 1.7e-10 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KPLABODI_00117 1.3e-30
KPLABODI_00121 1.7e-24 S Uncharacterised protein conserved in bacteria (DUF2313)
KPLABODI_00122 7.3e-105 xkdT S Baseplate J-like protein
KPLABODI_00123 3.6e-23 S Protein of unknown function (DUF2634)
KPLABODI_00124 9e-27 S Protein of unknown function (DUF2577)
KPLABODI_00125 3.8e-61 yqbQ G PFAM Phage late control gene D protein (GPD)
KPLABODI_00126 2.6e-30 ygaU GH23 S protein containing LysM domain
KPLABODI_00127 1.2e-97 S phage tail tape measure protein
KPLABODI_00128 4.3e-31 xkdN S Phage XkdN-like tail assembly chaperone protein, TAC
KPLABODI_00129 2e-45 S Protein of unknown function (DUF2001)
KPLABODI_00130 7.2e-112 S Phage tail sheath protein
KPLABODI_00132 4.2e-10
KPLABODI_00133 4e-26 S Bacteriophage HK97-gp10, putative tail-component
KPLABODI_00134 7.5e-32
KPLABODI_00135 2.2e-21
KPLABODI_00136 7.2e-103
KPLABODI_00137 5.2e-37 S Phage minor structural protein GP20
KPLABODI_00138 5.9e-90 S Phage Mu protein F like protein
KPLABODI_00139 1.4e-177 S Phage portal protein, SPP1 Gp6-like
KPLABODI_00140 4.3e-156 S Terminase-like family
KPLABODI_00141 4e-40 L Terminase small subunit
KPLABODI_00142 1.8e-81
KPLABODI_00147 2.2e-09
KPLABODI_00148 3.2e-54 S VRR-NUC domain
KPLABODI_00149 0.0 S Phage plasmid primase, P4
KPLABODI_00150 8.3e-80 S Protein of unknown function (DUF669)
KPLABODI_00151 2.1e-148 res L Helicase C-terminal domain protein
KPLABODI_00152 1.7e-21 S AAA domain
KPLABODI_00157 4.4e-37 ansR 3.4.21.88 K sequence-specific DNA binding
KPLABODI_00158 9.5e-11 E Zn peptidase
KPLABODI_00159 3.4e-24 S Domain of Unknown Function with PDB structure (DUF3862)
KPLABODI_00160 2.1e-189 S Phage integrase family
KPLABODI_00161 5.3e-104 S Protein of unknown function (DUF3644)
KPLABODI_00163 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPLABODI_00164 2.8e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
KPLABODI_00165 1.9e-11 comGF U Putative Competence protein ComGF
KPLABODI_00167 2.3e-75
KPLABODI_00168 6.5e-51 comGC U competence protein ComGC
KPLABODI_00169 4.9e-158 comGB NU type II secretion system
KPLABODI_00170 4.4e-180 comGA NU Type II IV secretion system protein
KPLABODI_00171 1.4e-130 yebC K Transcriptional regulatory protein
KPLABODI_00172 2e-94 S VanZ like family
KPLABODI_00173 1.2e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
KPLABODI_00174 8.9e-158 rssA S Phospholipase, patatin family
KPLABODI_00175 2.2e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPLABODI_00176 0.0 E Amino acid permease
KPLABODI_00177 7.2e-68 GM epimerase
KPLABODI_00178 6.3e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPLABODI_00179 1.2e-65
KPLABODI_00180 1.5e-25
KPLABODI_00181 5e-265 T Diguanylate cyclase, GGDEF domain
KPLABODI_00182 5.8e-197 yliE T EAL domain
KPLABODI_00183 2.5e-49
KPLABODI_00184 5.2e-33
KPLABODI_00185 5e-60 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPLABODI_00186 4.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPLABODI_00187 0.0 copA 3.6.3.54 P P-type ATPase
KPLABODI_00188 2.5e-54 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KPLABODI_00189 1.4e-77 atkY K Copper transport repressor CopY TcrY
KPLABODI_00190 2e-55 V peptidase activity
KPLABODI_00191 6.8e-150 S hydrolase
KPLABODI_00192 5.3e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPLABODI_00193 5.7e-164 ybbR S YbbR-like protein
KPLABODI_00194 4.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPLABODI_00195 2.4e-206 potD P ABC transporter
KPLABODI_00196 5.6e-128 potC P ABC transporter permease
KPLABODI_00197 1.1e-144 potB P ABC transporter permease
KPLABODI_00198 1.4e-203 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KPLABODI_00199 2.9e-162 murB 1.3.1.98 M Cell wall formation
KPLABODI_00200 1.2e-97 dnaQ 2.7.7.7 L DNA polymerase III
KPLABODI_00201 4.2e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KPLABODI_00202 9.7e-183 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KPLABODI_00203 1.5e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPLABODI_00204 2.6e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
KPLABODI_00205 8e-105
KPLABODI_00206 8.6e-50 3.2.2.20 K acetyltransferase
KPLABODI_00207 8.3e-26 3.2.2.20 K acetyltransferase
KPLABODI_00208 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KPLABODI_00209 3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KPLABODI_00210 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KPLABODI_00211 1.8e-212 cggR K Putative sugar-binding domain
KPLABODI_00213 5.3e-136 XK27_08845 S ABC transporter, ATP-binding protein
KPLABODI_00214 3.8e-144 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KPLABODI_00215 1.6e-10 ABC-SBP S ABC transporter
KPLABODI_00216 1.2e-54 ABC-SBP S ABC transporter
KPLABODI_00218 6.1e-213
KPLABODI_00219 1.1e-37
KPLABODI_00220 5.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KPLABODI_00221 3.4e-169 whiA K May be required for sporulation
KPLABODI_00222 5e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KPLABODI_00223 2.4e-164 rapZ S Displays ATPase and GTPase activities
KPLABODI_00224 3e-81 dmpA 3.4.11.19 EQ Peptidase family S58
KPLABODI_00225 4.4e-146 E D-aminopeptidase
KPLABODI_00226 7.4e-92 S Short repeat of unknown function (DUF308)
KPLABODI_00227 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KPLABODI_00228 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KPLABODI_00229 4.9e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KPLABODI_00230 6.5e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KPLABODI_00231 2.9e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPLABODI_00232 1.2e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPLABODI_00233 9.1e-31
KPLABODI_00234 5.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KPLABODI_00235 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KPLABODI_00236 1.6e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPLABODI_00237 1.9e-121 comFC S Competence protein
KPLABODI_00238 2.7e-246 comFA L Helicase C-terminal domain protein
KPLABODI_00239 4.7e-117 yvyE 3.4.13.9 S YigZ family
KPLABODI_00240 3.1e-215 tagO 2.7.8.33, 2.7.8.35 M transferase
KPLABODI_00241 5.1e-221 rny S Endoribonuclease that initiates mRNA decay
KPLABODI_00242 4.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPLABODI_00243 2.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPLABODI_00244 2.7e-107 ymfM S Helix-turn-helix domain
KPLABODI_00245 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
KPLABODI_00246 3.9e-237 S Peptidase M16
KPLABODI_00247 3.5e-230 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
KPLABODI_00248 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KPLABODI_00249 1.9e-68 WQ51_03320 S Protein of unknown function (DUF1149)
KPLABODI_00250 8.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KPLABODI_00251 2.1e-181 yubA S AI-2E family transporter
KPLABODI_00252 3.5e-64 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KPLABODI_00258 7e-76 S Virulence-associated protein E
KPLABODI_00259 9.8e-22 S Primase alpha helix C-terminal domain protein
KPLABODI_00261 1.9e-18
KPLABODI_00263 1.5e-07 K Helix-turn-helix domain
KPLABODI_00264 1.3e-93 sip L Belongs to the 'phage' integrase family
KPLABODI_00265 1.1e-197 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KPLABODI_00266 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KPLABODI_00267 2.8e-22
KPLABODI_00268 1.2e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPLABODI_00269 3.9e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPLABODI_00270 3.1e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
KPLABODI_00271 3.3e-109 yjbK S CYTH
KPLABODI_00272 3.4e-112 yjbH Q Thioredoxin
KPLABODI_00273 4.4e-163 coiA 3.6.4.12 S Competence protein
KPLABODI_00274 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KPLABODI_00275 5e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KPLABODI_00276 2.1e-302 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KPLABODI_00277 1.2e-39 ptsH G phosphocarrier protein HPR
KPLABODI_00278 5.8e-10
KPLABODI_00279 0.0 clpE O Belongs to the ClpA ClpB family
KPLABODI_00280 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
KPLABODI_00281 5e-26 mco Q Multicopper oxidase
KPLABODI_00282 6.2e-205 mco Q Multicopper oxidase
KPLABODI_00283 2.5e-26
KPLABODI_00284 1.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KPLABODI_00285 1.2e-157 hlyX S Transporter associated domain
KPLABODI_00286 1.7e-73
KPLABODI_00287 4.5e-85
KPLABODI_00288 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
KPLABODI_00289 1.1e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPLABODI_00290 6.2e-182 D Alpha beta
KPLABODI_00291 2.8e-18
KPLABODI_00292 3e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KPLABODI_00293 4.5e-166 yihY S Belongs to the UPF0761 family
KPLABODI_00294 3.6e-162 map 3.4.11.18 E Methionine Aminopeptidase
KPLABODI_00295 2.9e-78 fld C Flavodoxin
KPLABODI_00296 3.3e-51 gtcA S Teichoic acid glycosylation protein
KPLABODI_00297 5.2e-212 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KPLABODI_00298 1.4e-24
KPLABODI_00299 2.6e-269 E Amino acid permease
KPLABODI_00301 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KPLABODI_00302 1.1e-228 ynbB 4.4.1.1 P aluminum resistance
KPLABODI_00303 1e-232 pyrP F Permease
KPLABODI_00304 4.7e-183 pfoS S Phosphotransferase system, EIIC
KPLABODI_00306 1.2e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPLABODI_00307 2.9e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
KPLABODI_00308 2.3e-122 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
KPLABODI_00309 6.4e-227 potE E amino acid
KPLABODI_00310 9.8e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KPLABODI_00311 2.1e-249 yhdP S Transporter associated domain
KPLABODI_00312 2.9e-21 3.4.22.70 M Sortase family
KPLABODI_00314 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KPLABODI_00315 1.2e-129 gntR K UbiC transcription regulator-associated domain protein
KPLABODI_00316 1.6e-174 rihB 3.2.2.1 F Nucleoside
KPLABODI_00317 5.5e-124 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPLABODI_00318 2e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KPLABODI_00319 1.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPLABODI_00320 5.9e-88
KPLABODI_00321 7.4e-10 S Protein of unknown function (DUF2974)
KPLABODI_00322 1.1e-269 S Uncharacterized protein conserved in bacteria (DUF2252)
KPLABODI_00323 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KPLABODI_00324 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KPLABODI_00325 9.6e-155 glnH ET Bacterial periplasmic substrate-binding proteins
KPLABODI_00326 4.4e-110 glnP P ABC transporter permease
KPLABODI_00327 5.5e-110 gluC P ABC transporter permease
KPLABODI_00328 6.4e-151 glnH ET ABC transporter substrate-binding protein
KPLABODI_00329 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KPLABODI_00330 2.5e-118 udk 2.7.1.48 F Zeta toxin
KPLABODI_00331 3.7e-111 udk 2.7.1.48 F Zeta toxin
KPLABODI_00333 7e-101 S ABC-type cobalt transport system, permease component
KPLABODI_00334 7.8e-210 pepA E M42 glutamyl aminopeptidase
KPLABODI_00335 2.2e-281 pipD E Dipeptidase
KPLABODI_00336 1.3e-142 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KPLABODI_00337 5e-120 ybhL S Belongs to the BI1 family
KPLABODI_00338 3.3e-217 mdtG EGP Major facilitator Superfamily
KPLABODI_00339 2.6e-56
KPLABODI_00341 6.1e-49 kgtP EGP Sugar (and other) transporter
KPLABODI_00342 5.3e-100 kgtP EGP Sugar (and other) transporter
KPLABODI_00343 2.2e-309 ybiT S ABC transporter, ATP-binding protein
KPLABODI_00344 5.5e-167 mleP3 S Membrane transport protein
KPLABODI_00345 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KPLABODI_00346 5.7e-36 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
KPLABODI_00347 1.1e-32 mtlD 1.1.1.17 G mannitol metabolic process
KPLABODI_00349 2.1e-52 mtlR K transcriptional antiterminator
KPLABODI_00350 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KPLABODI_00351 1.2e-85 K AsnC family
KPLABODI_00352 3.8e-52 ypaA S membrane
KPLABODI_00353 1.2e-26 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KPLABODI_00355 1.3e-30 yliE T Putative diguanylate phosphodiesterase
KPLABODI_00356 5.3e-76 T Gaf domain
KPLABODI_00357 2.5e-94 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
KPLABODI_00358 5.3e-124 alkD L DNA alkylation repair enzyme
KPLABODI_00359 6.9e-240 brnQ U Component of the transport system for branched-chain amino acids
KPLABODI_00360 2.8e-100 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KPLABODI_00361 8.3e-47 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
KPLABODI_00362 4.3e-33 copZ P Heavy-metal-associated domain
KPLABODI_00363 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
KPLABODI_00364 1.6e-56 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KPLABODI_00365 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
KPLABODI_00366 2.2e-159 L Mrr N-terminal domain
KPLABODI_00367 4.8e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPLABODI_00368 1.4e-117 S Protein of unknown function (DUF1211)
KPLABODI_00369 1.5e-169 yegS 2.7.1.107 G Lipid kinase
KPLABODI_00370 3.2e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPLABODI_00371 2.1e-266 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KPLABODI_00372 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPLABODI_00373 9.2e-193 camS S sex pheromone
KPLABODI_00374 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPLABODI_00375 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KPLABODI_00376 1.3e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
KPLABODI_00377 4.1e-102 S ECF transporter, substrate-specific component
KPLABODI_00379 1.8e-89 ydcK S Belongs to the SprT family
KPLABODI_00380 2.7e-111 V ABC transporter
KPLABODI_00383 0.0 pacL 3.6.3.8 P P-type ATPase
KPLABODI_00384 3.3e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KPLABODI_00385 3.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
KPLABODI_00386 1e-204 csaB M Glycosyl transferases group 1
KPLABODI_00387 1.4e-133 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KPLABODI_00388 1.5e-261 epsU S Polysaccharide biosynthesis protein
KPLABODI_00389 9.1e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KPLABODI_00390 3.9e-125 gntR1 K UTRA
KPLABODI_00391 1e-198
KPLABODI_00392 2.9e-215
KPLABODI_00393 1.4e-56 oppA2 E ABC transporter, substratebinding protein
KPLABODI_00396 8.8e-166 pfoS S Phosphotransferase system, EIIC
KPLABODI_00397 8.5e-226 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KPLABODI_00400 2.5e-91 S Phosphatidylethanolamine-binding protein
KPLABODI_00401 9.3e-48 EGP Major facilitator Superfamily
KPLABODI_00402 1.9e-52 EGP Major facilitator Superfamily
KPLABODI_00403 1.6e-119 XK27_07525 3.6.1.55 F NUDIX domain
KPLABODI_00404 1.2e-12 oppA E ABC transporter, substratebinding protein
KPLABODI_00405 6.9e-187 oppA E ABC transporter, substratebinding protein
KPLABODI_00406 1.6e-45
KPLABODI_00407 3.5e-23
KPLABODI_00408 3.9e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
KPLABODI_00409 4.2e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPLABODI_00410 6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KPLABODI_00411 2.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPLABODI_00412 4.4e-163 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPLABODI_00413 7.4e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPLABODI_00414 1.3e-61 rplQ J Ribosomal protein L17
KPLABODI_00415 5.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPLABODI_00416 1.4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPLABODI_00417 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPLABODI_00418 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KPLABODI_00419 5.9e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KPLABODI_00420 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KPLABODI_00421 1.8e-72 rplO J Binds to the 23S rRNA
KPLABODI_00422 1.3e-24 rpmD J Ribosomal protein L30
KPLABODI_00423 1.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KPLABODI_00424 5.7e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPLABODI_00425 2.8e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KPLABODI_00426 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPLABODI_00427 9.3e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPLABODI_00428 4.5e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPLABODI_00429 1.6e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KPLABODI_00430 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPLABODI_00431 3.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KPLABODI_00432 1.9e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KPLABODI_00433 9.4e-121 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KPLABODI_00434 8.9e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPLABODI_00435 4.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KPLABODI_00436 2.8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPLABODI_00437 8.3e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KPLABODI_00438 1.6e-106 rplD J Forms part of the polypeptide exit tunnel
KPLABODI_00439 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPLABODI_00440 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KPLABODI_00441 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPLABODI_00442 3.5e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KPLABODI_00443 1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KPLABODI_00446 9e-08 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KPLABODI_00447 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPLABODI_00448 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPLABODI_00451 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KPLABODI_00452 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
KPLABODI_00456 1.1e-107 XK27_00160 S Domain of unknown function (DUF5052)
KPLABODI_00457 1.1e-217 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KPLABODI_00458 4.1e-22 metY 2.5.1.49 E o-acetylhomoserine
KPLABODI_00460 6.6e-139 T diguanylate cyclase activity
KPLABODI_00462 2.5e-278 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KPLABODI_00463 1.1e-197 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPLABODI_00464 1.3e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KPLABODI_00465 5e-301 E ABC transporter, substratebinding protein
KPLABODI_00466 5.3e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPLABODI_00467 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPLABODI_00468 2.7e-249 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KPLABODI_00469 7.5e-61 yabR J S1 RNA binding domain
KPLABODI_00470 1.5e-59 divIC D Septum formation initiator
KPLABODI_00471 3.2e-34 yabO J S4 domain protein
KPLABODI_00472 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPLABODI_00473 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KPLABODI_00474 2e-126 S (CBS) domain
KPLABODI_00475 2.6e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPLABODI_00476 9.4e-71 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KPLABODI_00477 8.2e-239 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KPLABODI_00478 2.7e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KPLABODI_00479 1.6e-41 rpmE2 J Ribosomal protein L31
KPLABODI_00480 1.9e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPLABODI_00481 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KPLABODI_00482 1.1e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KPLABODI_00483 2.5e-65 S Domain of unknown function (DUF1934)
KPLABODI_00484 2.8e-254 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
KPLABODI_00485 6.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPLABODI_00486 6.8e-43
KPLABODI_00487 4e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPLABODI_00488 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KPLABODI_00489 6.4e-38 veg S Biofilm formation stimulator VEG
KPLABODI_00490 6.8e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KPLABODI_00491 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPLABODI_00492 3.3e-149 tatD L hydrolase, TatD family
KPLABODI_00493 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPLABODI_00494 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KPLABODI_00495 1.2e-103 S TPM domain
KPLABODI_00496 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
KPLABODI_00497 3.3e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPLABODI_00499 1.1e-118
KPLABODI_00500 5e-75 KLT Protein kinase domain
KPLABODI_00501 1.4e-37 S Aromatic-ring-opening dioxygenase LigAB, LigA subunit
KPLABODI_00502 1.5e-129 V ATPases associated with a variety of cellular activities
KPLABODI_00503 5e-137 V ABC-2 type transporter
KPLABODI_00504 2.9e-116 E peptidase
KPLABODI_00506 4.1e-41 S Enterocin A Immunity
KPLABODI_00507 2.9e-251 L Putative transposase DNA-binding domain
KPLABODI_00508 7.5e-146 2.7.7.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KPLABODI_00509 2e-42 L Membrane
KPLABODI_00510 1.1e-106
KPLABODI_00511 1.3e-107 pncA Q Isochorismatase family
KPLABODI_00512 7.8e-54 L Transposase and inactivated derivatives, IS30 family
KPLABODI_00513 3.1e-39 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KPLABODI_00514 9.7e-115 dnaD L DnaD domain protein
KPLABODI_00515 7.2e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPLABODI_00516 6.8e-150 S Sucrose-6F-phosphate phosphohydrolase
KPLABODI_00517 2.1e-70 I Psort location Cytoplasmic, score
KPLABODI_00518 1.9e-54 I acetylesterase activity
KPLABODI_00519 2.4e-189 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPLABODI_00520 0.0 dap2 3.4.19.1 E Prolyl oligopeptidase family
KPLABODI_00521 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KPLABODI_00522 2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KPLABODI_00523 3.2e-106 ypsA S Belongs to the UPF0398 family
KPLABODI_00524 1e-57 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KPLABODI_00525 3.3e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KPLABODI_00526 2e-106 XK27_01810 S Calcineurin-like phosphoesterase
KPLABODI_00527 4.4e-67 XK27_01810 S Calcineurin-like phosphoesterase
KPLABODI_00528 5.4e-59
KPLABODI_00529 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KPLABODI_00530 9.3e-72 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KPLABODI_00531 1e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPLABODI_00532 7.4e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KPLABODI_00533 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
KPLABODI_00534 5.6e-43 gcvR T Belongs to the UPF0237 family
KPLABODI_00535 2.9e-246 XK27_08635 S UPF0210 protein
KPLABODI_00536 3.7e-307 FbpA K Fibronectin-binding protein
KPLABODI_00537 6.3e-157 degV S EDD domain protein, DegV family
KPLABODI_00538 7.5e-173
KPLABODI_00539 4.9e-165 EG EamA-like transporter family
KPLABODI_00540 6.1e-120 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPLABODI_00541 3.3e-86 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPLABODI_00542 1.1e-83 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KPLABODI_00543 1.1e-84 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KPLABODI_00544 1.4e-115 3.1.3.73 G phosphoglycerate mutase
KPLABODI_00545 4.7e-13 XK27_06780 V ABC transporter permease
KPLABODI_00546 6e-91 C Nitroreductase family
KPLABODI_00547 9.8e-60 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KPLABODI_00549 5.1e-201 xerS L Belongs to the 'phage' integrase family
KPLABODI_00550 2.4e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KPLABODI_00551 2.9e-194 S Uncharacterized protein conserved in bacteria (DUF2325)
KPLABODI_00552 1.8e-72 S Sel1-like repeats.
KPLABODI_00553 1.3e-129 T Diguanylate cyclase, GGDEF domain
KPLABODI_00555 6.6e-21 S Domain of unknown function (DUF4343)
KPLABODI_00556 6.8e-77 GM NmrA-like family
KPLABODI_00557 1.2e-177 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
KPLABODI_00558 7.4e-83 S An automated process has identified a potential problem with this gene model
KPLABODI_00559 1e-140 S Protein of unknown function (DUF3100)
KPLABODI_00560 2.5e-247 3.5.1.47 S Peptidase dimerisation domain
KPLABODI_00562 6.3e-08 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
KPLABODI_00563 3.9e-262 S Uncharacterised protein family (UPF0236)
KPLABODI_00564 5.4e-109 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPLABODI_00565 8e-79
KPLABODI_00566 1.2e-59 ypmB S Protein conserved in bacteria
KPLABODI_00567 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KPLABODI_00568 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KPLABODI_00569 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KPLABODI_00570 3.7e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
KPLABODI_00571 7.7e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KPLABODI_00572 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KPLABODI_00573 3.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KPLABODI_00574 1.4e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
KPLABODI_00575 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPLABODI_00576 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPLABODI_00577 1.3e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KPLABODI_00578 7.6e-31 yfiC V ABC transporter
KPLABODI_00579 2.1e-185 yfiC V ABC transporter
KPLABODI_00580 2.8e-52 V abc transporter atp-binding protein
KPLABODI_00581 1e-41 V ABC transporter, ATP-binding protein
KPLABODI_00583 8.3e-48 lmrA V (ABC) transporter
KPLABODI_00584 5.7e-15 K Winged helix DNA-binding domain
KPLABODI_00585 5e-153 supH G Sucrose-6F-phosphate phosphohydrolase
KPLABODI_00586 9e-104
KPLABODI_00587 2.5e-189 2.7.7.65 T diguanylate cyclase
KPLABODI_00588 4e-209 yliE T Putative diguanylate phosphodiesterase
KPLABODI_00589 5e-71 yliE T Putative diguanylate phosphodiesterase
KPLABODI_00591 8.4e-103 2.7.7.65 T phosphorelay sensor kinase activity
KPLABODI_00592 7.8e-135 cbiQ P Cobalt transport protein
KPLABODI_00593 3.8e-148 P ABC transporter
KPLABODI_00594 7.2e-141 cbiO2 P ABC transporter
KPLABODI_00595 1.5e-101 S C4-dicarboxylate anaerobic carrier
KPLABODI_00596 6.6e-104 I NUDIX domain
KPLABODI_00597 7.6e-129 S Glycosyl hydrolases family 18
KPLABODI_00598 3e-47 S Glycosyl hydrolases family 18
KPLABODI_00599 7e-121 3.6.1.13 L NUDIX domain
KPLABODI_00601 3.2e-65 lsa S ABC transporter
KPLABODI_00602 8.4e-16 lsa S ABC transporter
KPLABODI_00603 3.3e-32 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KPLABODI_00604 2.4e-21 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KPLABODI_00605 4.1e-303 phoR 2.7.13.3 T Histidine kinase
KPLABODI_00606 1.4e-124 T Transcriptional regulatory protein, C terminal
KPLABODI_00607 2e-112 phoU P Plays a role in the regulation of phosphate uptake
KPLABODI_00608 3.2e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPLABODI_00609 2.8e-157 pstA P Phosphate transport system permease protein PstA
KPLABODI_00610 4.3e-161 pstC P probably responsible for the translocation of the substrate across the membrane
KPLABODI_00611 1.7e-154 pstS P Phosphate
KPLABODI_00614 2.5e-129 yliE T Putative diguanylate phosphodiesterase
KPLABODI_00615 2e-36
KPLABODI_00616 1.2e-74 oppA E ABC transporter, substratebinding protein
KPLABODI_00617 7.6e-92 oppA E ABC transporter, substratebinding protein
KPLABODI_00619 4.5e-64 S Domain of unknown function DUF1828
KPLABODI_00620 8.8e-218 EGP Major facilitator Superfamily
KPLABODI_00621 2.8e-257 glnA 6.3.1.2 E glutamine synthetase
KPLABODI_00622 1.2e-138 ynbB 4.4.1.1 P aluminum resistance
KPLABODI_00623 3.4e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPLABODI_00624 2.6e-70 yqhL P Rhodanese-like protein
KPLABODI_00625 9.5e-33 yqgQ S Bacterial protein of unknown function (DUF910)
KPLABODI_00626 7.7e-115 gluP 3.4.21.105 S Rhomboid family
KPLABODI_00627 4.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPLABODI_00628 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KPLABODI_00629 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KPLABODI_00630 0.0 S membrane
KPLABODI_00631 2e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPLABODI_00632 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPLABODI_00633 2.1e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPLABODI_00634 2e-61 yodB K Transcriptional regulator, HxlR family
KPLABODI_00635 1.2e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPLABODI_00636 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KPLABODI_00637 4.9e-155 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPLABODI_00638 3e-290 arlS 2.7.13.3 T Histidine kinase
KPLABODI_00639 6.5e-128 K response regulator
KPLABODI_00640 8.4e-102 yceD S Uncharacterized ACR, COG1399
KPLABODI_00641 1.9e-214 ylbM S Belongs to the UPF0348 family
KPLABODI_00642 1.2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KPLABODI_00643 1.9e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KPLABODI_00644 8.4e-119 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPLABODI_00645 2.3e-212 yqeH S Ribosome biogenesis GTPase YqeH
KPLABODI_00646 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPLABODI_00647 1.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KPLABODI_00648 2.6e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KPLABODI_00649 3.9e-237 L Putative transposase DNA-binding domain
KPLABODI_00650 5.4e-113 guaB2 L Resolvase, N terminal domain
KPLABODI_00651 1.3e-273 S Archaea bacterial proteins of unknown function
KPLABODI_00652 2.3e-32
KPLABODI_00653 2.9e-42
KPLABODI_00654 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPLABODI_00655 1.3e-168 dnaI L Primosomal protein DnaI
KPLABODI_00656 3.4e-247 dnaB L Replication initiation and membrane attachment
KPLABODI_00657 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPLABODI_00658 2.5e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPLABODI_00659 1.7e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KPLABODI_00660 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPLABODI_00661 4.2e-40 EGP Major facilitator Superfamily
KPLABODI_00662 2.7e-112 EGP Major facilitator Superfamily
KPLABODI_00663 1.1e-42 EGP Major facilitator Superfamily
KPLABODI_00664 4.8e-165 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KPLABODI_00665 2.8e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KPLABODI_00666 1.4e-74
KPLABODI_00667 3.5e-67
KPLABODI_00668 1.4e-139
KPLABODI_00669 1.5e-94
KPLABODI_00670 9.1e-110 V AAA domain, putative AbiEii toxin, Type IV TA system
KPLABODI_00671 1.1e-103
KPLABODI_00672 1e-114
KPLABODI_00673 4.4e-92
KPLABODI_00674 2.3e-70
KPLABODI_00675 5.1e-17 lmrA 3.6.3.44 V ABC transporter
KPLABODI_00676 4.1e-281 clcA P chloride
KPLABODI_00677 3.7e-230 pbuG S permease
KPLABODI_00678 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KPLABODI_00679 2.2e-268 glnP P ABC transporter
KPLABODI_00680 1.4e-127 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KPLABODI_00681 2.6e-123 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KPLABODI_00682 8.4e-38
KPLABODI_00683 3.4e-166 3.2.1.17 M peptidoglycan-binding domain-containing protein
KPLABODI_00685 1.2e-13 L PFAM Integrase catalytic region
KPLABODI_00687 1.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KPLABODI_00688 2.4e-158 yeaE S Aldo/keto reductase family
KPLABODI_00689 2.5e-21 EGP Major facilitator Superfamily
KPLABODI_00690 2.2e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KPLABODI_00691 6.8e-204 yufP S Belongs to the binding-protein-dependent transport system permease family
KPLABODI_00692 2.1e-285 xylG 3.6.3.17 S ABC transporter
KPLABODI_00693 2.3e-193 tcsA S ABC transporter substrate-binding protein PnrA-like
KPLABODI_00694 5e-196 tcsA S ABC transporter substrate-binding protein PnrA-like
KPLABODI_00695 1e-70 S Domain of unknown function (DUF4352)
KPLABODI_00696 7.3e-189 KLT Protein tyrosine kinase
KPLABODI_00697 1.1e-66 S Psort location Cytoplasmic, score
KPLABODI_00699 2.7e-194 tcsA S ABC transporter substrate-binding protein PnrA-like
KPLABODI_00700 2.6e-200 S DUF218 domain
KPLABODI_00701 2.9e-122 S CAAX protease self-immunity
KPLABODI_00702 9.3e-201 napA P Sodium/hydrogen exchanger family
KPLABODI_00703 0.0 cadA P P-type ATPase
KPLABODI_00704 1.2e-85 ykuL S (CBS) domain
KPLABODI_00705 3.7e-66 L An automated process has identified a potential problem with this gene model
KPLABODI_00707 1.6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KPLABODI_00708 1e-156 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KPLABODI_00709 7.5e-230 M ErfK YbiS YcfS YnhG
KPLABODI_00711 2.6e-48 L Putative transposase DNA-binding domain
KPLABODI_00712 7e-55 L Putative transposase DNA-binding domain
KPLABODI_00713 2.5e-57
KPLABODI_00714 1e-57 3.4.22.70 M Sortase family
KPLABODI_00715 4.7e-96 M ErfK YbiS YcfS YnhG
KPLABODI_00716 3.9e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KPLABODI_00717 5.3e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPLABODI_00718 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KPLABODI_00719 8.1e-55 yheA S Belongs to the UPF0342 family
KPLABODI_00720 3.9e-226 yhaO L Ser Thr phosphatase family protein
KPLABODI_00721 0.0 L AAA domain
KPLABODI_00722 1.1e-178 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
KPLABODI_00723 4.7e-66 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F shikimate kinase activity
KPLABODI_00724 9.8e-52 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KPLABODI_00725 1.1e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KPLABODI_00726 2.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPLABODI_00727 1.2e-132 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KPLABODI_00728 5.2e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KPLABODI_00729 1.8e-54
KPLABODI_00730 1.5e-79 hit FG Scavenger mRNA decapping enzyme C-term binding
KPLABODI_00731 1.8e-136 ecsA V ABC transporter, ATP-binding protein
KPLABODI_00732 1.1e-217 ecsB U ABC transporter
KPLABODI_00733 5.2e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KPLABODI_00734 1.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KPLABODI_00735 3.4e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPLABODI_00736 4.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KPLABODI_00737 2e-112 K Helix-turn-helix domain
KPLABODI_00738 3.8e-65 L MobA MobL family protein
KPLABODI_00739 2.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
KPLABODI_00740 3.5e-104 dedA 3.1.3.1 S SNARE associated Golgi protein
KPLABODI_00741 3.7e-31
KPLABODI_00742 4.6e-23
KPLABODI_00743 8.8e-70 K GNAT family
KPLABODI_00744 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
KPLABODI_00745 4e-228 4.4.1.8 E Aminotransferase, class I
KPLABODI_00746 1.3e-165 htpX O Peptidase family M48
KPLABODI_00747 6.4e-77 1.6.5.2 GM NmrA-like family
KPLABODI_00748 3.6e-10 1.6.5.2 GM NAD(P)H-binding
KPLABODI_00749 3e-78 K Transcriptional regulator
KPLABODI_00750 1.2e-169 E ABC transporter, ATP-binding protein
KPLABODI_00751 7.2e-278 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KPLABODI_00752 1.2e-266 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KPLABODI_00753 8e-117 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KPLABODI_00754 2.1e-137 prsW S Involved in the degradation of specific anti-sigma factors
KPLABODI_00755 5.6e-112 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KPLABODI_00756 1.3e-25
KPLABODI_00757 4.2e-138
KPLABODI_00758 1.3e-174
KPLABODI_00759 7.8e-266 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
KPLABODI_00760 7.1e-158 3.4.17.13 V LD-carboxypeptidase
KPLABODI_00762 2.8e-12 D Filamentation induced by cAMP protein fic
KPLABODI_00763 1.3e-08 D Filamentation induced by cAMP protein fic
KPLABODI_00764 9.8e-77 1.3.5.4 C FMN_bind
KPLABODI_00765 3.5e-108 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
KPLABODI_00766 2.8e-131 ydcF S Gram-negative-bacterium-type cell wall biogenesis
KPLABODI_00767 4.1e-99 yyaQ S YjbR
KPLABODI_00768 4.4e-146 ligA 2.7.7.7, 6.5.1.2 L EXOIII
KPLABODI_00769 5.4e-107 L COG3547 Transposase and inactivated derivatives
KPLABODI_00770 1.3e-131 C FAD binding domain
KPLABODI_00772 2e-132 gph 3.1.3.18 S HAD-hyrolase-like
KPLABODI_00773 2.6e-42 yjdJ S GCN5-related N-acetyl-transferase
KPLABODI_00775 8.4e-63 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPLABODI_00776 2.6e-162 rnhA 3.1.26.4 L Resolvase, N-terminal
KPLABODI_00777 2e-18 P Rhodanese Homology Domain
KPLABODI_00778 0.0 V ABC transporter transmembrane region
KPLABODI_00779 3.4e-308 XK27_09600 V ABC transporter, ATP-binding protein
KPLABODI_00780 3.4e-77 K Transcriptional regulator, MarR family
KPLABODI_00781 9.1e-164 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPLABODI_00782 2.9e-78 V Psort location CytoplasmicMembrane, score
KPLABODI_00783 4.1e-167 V Psort location CytoplasmicMembrane, score 10.00
KPLABODI_00784 5.9e-46 V (ABC) transporter
KPLABODI_00785 1.4e-113 ylbE GM NAD(P)H-binding
KPLABODI_00786 2.6e-85 S Hydrolases of the alpha beta superfamily
KPLABODI_00787 3.1e-57
KPLABODI_00788 0.0 yacH D Putative exonuclease SbcCD, C subunit
KPLABODI_00791 1.1e-19 S Protein of unknown function N-terminus (DUF3323)
KPLABODI_00792 1e-47 GM epimerase
KPLABODI_00793 6e-71 K Transcriptional regulator
KPLABODI_00794 2.2e-41 WQ51_05710 S Mitochondrial biogenesis AIM24
KPLABODI_00795 2.5e-80 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KPLABODI_00796 1e-69 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KPLABODI_00797 5.6e-81 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KPLABODI_00798 3.7e-102 ybaJ Q Methyltransferase domain
KPLABODI_00799 1.3e-36 V (ABC) transporter
KPLABODI_00800 0.0 carB 6.3.5.5 F Psort location Cytoplasmic, score 8.87
KPLABODI_00801 2.3e-88 carB 6.3.5.5 F Psort location Cytoplasmic, score 8.87
KPLABODI_00802 6.6e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KPLABODI_00803 8.6e-37 T diguanylate cyclase activity
KPLABODI_00805 1.3e-117 V MATE efflux family protein
KPLABODI_00806 6.1e-74 V MATE efflux family protein
KPLABODI_00807 6.1e-73 prpH 3.1.3.16 K 3.5.2 Transcription regulation
KPLABODI_00808 5.1e-15 prpH 3.1.3.16 K 3.5.2 Transcription regulation
KPLABODI_00809 6.2e-74 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KPLABODI_00810 2.5e-106 L Integrase
KPLABODI_00811 5.4e-76 cylB U ABC-2 type transporter
KPLABODI_00812 2.7e-76
KPLABODI_00813 3.1e-71 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
KPLABODI_00814 3.3e-130 cysA V ABC transporter, ATP-binding protein
KPLABODI_00815 0.0 V FtsX-like permease family
KPLABODI_00816 5.4e-13 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
KPLABODI_00817 1.8e-28 K Bacterial regulatory helix-turn-helix protein, lysR family
KPLABODI_00818 3.3e-83 1.3.5.4 C FAD binding domain
KPLABODI_00819 7.5e-194 1.3.5.4 C FAD binding domain
KPLABODI_00820 2.6e-09 S Motility quorum-sensing regulator, toxin of MqsA
KPLABODI_00822 3.2e-106 ydaF J Acetyltransferase (GNAT) domain
KPLABODI_00823 2e-89 S biotin transmembrane transporter activity
KPLABODI_00824 1.3e-42
KPLABODI_00825 1.1e-119
KPLABODI_00826 8.1e-13
KPLABODI_00827 4.7e-125 gpmB G Phosphoglycerate mutase family
KPLABODI_00828 1.2e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KPLABODI_00829 1.1e-103 T EAL domain
KPLABODI_00830 1.7e-145 yitS S EDD domain protein, DegV family
KPLABODI_00831 5.5e-92 racA K Domain of unknown function (DUF1836)
KPLABODI_00832 1.3e-179 yfdH GT2 M Glycosyltransferase like family 2
KPLABODI_00833 0.0 S Bacterial membrane protein, YfhO
KPLABODI_00834 5.7e-167 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KPLABODI_00835 4.2e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KPLABODI_00836 3.9e-84 K DNA-templated transcription, initiation
KPLABODI_00838 3.9e-139
KPLABODI_00839 3.5e-18 yliE T EAL domain
KPLABODI_00840 3.7e-28 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KPLABODI_00841 8.1e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
KPLABODI_00842 6.9e-25 bgl 3.2.1.21, 3.2.1.86 GT1 G beta-glucosidase activity
KPLABODI_00844 6.9e-25 bgl 3.2.1.21, 3.2.1.86 GT1 G beta-glucosidase activity
KPLABODI_00847 9.2e-73 cydD V abc transporter atp-binding protein
KPLABODI_00848 1.4e-275 sufB O assembly protein SufB
KPLABODI_00849 3.3e-74 nifU C SUF system FeS assembly protein, NifU family
KPLABODI_00850 1.3e-224 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPLABODI_00851 4e-220 sufD O FeS assembly protein SufD
KPLABODI_00852 5.9e-143 sufC O FeS assembly ATPase SufC
KPLABODI_00853 6e-91 yjcF S Acetyltransferase (GNAT) domain
KPLABODI_00854 8.1e-232 isp2 L Transposase
KPLABODI_00856 1.8e-119 V ABC transporter, ATP-binding protein
KPLABODI_00857 1.9e-215 S FtsX-like permease family
KPLABODI_00860 8e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KPLABODI_00861 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KPLABODI_00862 2.9e-29 secG U Preprotein translocase
KPLABODI_00863 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KPLABODI_00864 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPLABODI_00865 2.2e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
KPLABODI_00866 2.6e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
KPLABODI_00869 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPLABODI_00870 7.4e-166 S Alpha/beta hydrolase of unknown function (DUF915)
KPLABODI_00871 4.4e-149 S Sucrose-6F-phosphate phosphohydrolase
KPLABODI_00872 3.3e-138 puuD S peptidase C26
KPLABODI_00873 5.3e-159 yicL EG EamA-like transporter family
KPLABODI_00874 5.7e-49 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KPLABODI_00875 9e-31 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
KPLABODI_00876 1.9e-132 L Transposase
KPLABODI_00877 1.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KPLABODI_00878 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPLABODI_00879 4.2e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KPLABODI_00880 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KPLABODI_00881 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KPLABODI_00882 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KPLABODI_00883 1.6e-66 brnQ U Component of the transport system for branched-chain amino acids
KPLABODI_00884 7e-25 5.99.1.2 T diguanylate cyclase
KPLABODI_00885 2.1e-72 5.99.1.2 T diguanylate cyclase
KPLABODI_00886 1.3e-08 T diguanylate cyclase
KPLABODI_00887 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
KPLABODI_00888 8.6e-37
KPLABODI_00889 1.4e-129 cobQ S glutamine amidotransferase
KPLABODI_00890 2.5e-27 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPLABODI_00891 2.4e-144 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPLABODI_00892 4e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
KPLABODI_00893 0.0 KLT serine threonine protein kinase
KPLABODI_00894 7.2e-289 V ABC-type multidrug transport system, ATPase and permease components
KPLABODI_00895 2e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
KPLABODI_00896 4.4e-91 ymdB S Macro domain protein
KPLABODI_00897 2.4e-34
KPLABODI_00898 2.4e-151
KPLABODI_00901 2.5e-264 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KPLABODI_00902 1e-257 P Sodium:sulfate symporter transmembrane region
KPLABODI_00904 4.4e-255 pipD M Peptidase family C69
KPLABODI_00905 8.7e-173 citR K Putative sugar-binding domain
KPLABODI_00906 6.3e-36 lysM M LysM domain
KPLABODI_00907 0.0 pepN 3.4.11.2 E aminopeptidase
KPLABODI_00908 2.9e-34 drgA C Nitroreductase family
KPLABODI_00909 5.9e-227 S Putative peptidoglycan binding domain
KPLABODI_00910 6e-117
KPLABODI_00911 4.2e-138 S Belongs to the UPF0246 family
KPLABODI_00912 2.1e-64 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
KPLABODI_00913 7.6e-120 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
KPLABODI_00914 2.1e-88 ygfC K transcriptional regulator (TetR family)
KPLABODI_00915 7.7e-186 hrtB V ABC transporter permease
KPLABODI_00916 4.4e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KPLABODI_00917 8e-171 K WYL domain
KPLABODI_00918 1.3e-66 S pyridoxamine 5-phosphate
KPLABODI_00919 5.9e-11 K LytTr DNA-binding domain
KPLABODI_00920 1.3e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KPLABODI_00921 1.1e-139
KPLABODI_00923 2e-107
KPLABODI_00924 1.8e-116 V AAA domain, putative AbiEii toxin, Type IV TA system
KPLABODI_00925 1.1e-16
KPLABODI_00926 1.6e-276 pipD E Dipeptidase
KPLABODI_00927 1.5e-97 K WHG domain
KPLABODI_00928 9.9e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
KPLABODI_00929 5e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
KPLABODI_00930 3e-142 3.1.3.48 T Tyrosine phosphatase family
KPLABODI_00931 2e-188 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPLABODI_00932 5.3e-87 cvpA S Colicin V production protein
KPLABODI_00933 7.4e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KPLABODI_00934 3.3e-144 noc K Belongs to the ParB family
KPLABODI_00935 2.6e-138 soj D Sporulation initiation inhibitor
KPLABODI_00936 7.8e-155 spo0J K Belongs to the ParB family
KPLABODI_00937 2.5e-45 yyzM S Bacterial protein of unknown function (DUF951)
KPLABODI_00938 6.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KPLABODI_00939 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
KPLABODI_00940 0.0 V ABC transporter, ATP-binding protein
KPLABODI_00941 0.0 ndvA V ABC transporter
KPLABODI_00942 1e-122 K response regulator
KPLABODI_00943 1.6e-219 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
KPLABODI_00944 6.4e-298 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPLABODI_00945 5.2e-144 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KPLABODI_00946 9.8e-135 fruR K DeoR C terminal sensor domain
KPLABODI_00947 4.5e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KPLABODI_00948 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
KPLABODI_00949 1.6e-143 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
KPLABODI_00950 8.6e-119 fhuC P ABC transporter
KPLABODI_00951 8e-135 znuB U ABC 3 transport family
KPLABODI_00952 8.3e-49 KT response to antibiotic
KPLABODI_00953 1.7e-100 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KPLABODI_00954 0.0 pepF E oligoendopeptidase F
KPLABODI_00955 4.2e-250 L Putative transposase DNA-binding domain
KPLABODI_00956 1.1e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPLABODI_00957 2.7e-16
KPLABODI_00958 9.5e-294 S ABC transporter, ATP-binding protein
KPLABODI_00959 2.8e-137 thrE S Putative threonine/serine exporter
KPLABODI_00960 1.4e-84 S Threonine/Serine exporter, ThrE
KPLABODI_00961 4.1e-76
KPLABODI_00962 2.2e-111
KPLABODI_00963 2.9e-290 S O-antigen ligase like membrane protein
KPLABODI_00964 7.2e-45
KPLABODI_00965 1.9e-95 gmk2 2.7.4.8 F Guanylate kinase homologues.
KPLABODI_00966 5.6e-83 M NlpC P60 family
KPLABODI_00967 1.4e-200 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPLABODI_00968 1.9e-75 M NlpC/P60 family
KPLABODI_00969 1.5e-106 M NlpC P60 family protein
KPLABODI_00970 1.2e-123 M NlpC P60 family protein
KPLABODI_00971 1.8e-115 M NlpC P60 family protein
KPLABODI_00972 3e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPLABODI_00973 2.1e-175 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPLABODI_00974 2.2e-109 epsB M biosynthesis protein
KPLABODI_00975 9.8e-114 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KPLABODI_00976 7.5e-146 ywqE 3.1.3.48 GM PHP domain protein
KPLABODI_00977 5.8e-123 rfbP M Bacterial sugar transferase
KPLABODI_00978 5.2e-86 cpsF M Oligosaccharide biosynthesis protein Alg14 like
KPLABODI_00979 1.2e-83 pssE S Glycosyltransferase family 28 C-terminal domain
KPLABODI_00980 1.8e-88 M Domain of unknown function (DUF4422)
KPLABODI_00981 2e-17
KPLABODI_00982 3e-188 glf 5.4.99.9 M UDP-galactopyranose mutase
KPLABODI_00983 1.4e-60 cps2I M Spore coat protein
KPLABODI_00984 1.1e-41 L DDE superfamily endonuclease
KPLABODI_00985 2.3e-28 L DDE superfamily endonuclease
KPLABODI_00986 4.7e-70 L DDE superfamily endonuclease
KPLABODI_00987 1.8e-116 S Membrane protein involved in the export of O-antigen and teichoic acid
KPLABODI_00988 4.7e-35 gpsA 1.1.1.94 I Rossmann-like domain
KPLABODI_00989 2.6e-41 S Core-2/I-Branching enzyme
KPLABODI_00990 8.7e-201 GT4 M Glycosyl transferases group 1
KPLABODI_00991 1.3e-102 L Transposase and inactivated derivatives
KPLABODI_00992 3.3e-39 L Transposase and inactivated derivatives
KPLABODI_00993 0.0 mcrB V AAA domain (dynein-related subfamily)
KPLABODI_00994 8.2e-119 mcrC V McrBC 5-methylcytosine restriction system component
KPLABODI_00995 7.4e-13 K Bacterial regulatory proteins, tetR family
KPLABODI_00996 2e-96 L nuclease
KPLABODI_00997 3.8e-154 F DNA/RNA non-specific endonuclease
KPLABODI_00998 3.3e-11
KPLABODI_00999 4.8e-175 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KPLABODI_01000 2.7e-59 K Bacterial regulatory proteins, tetR family
KPLABODI_01001 5.4e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KPLABODI_01003 8.5e-39 higA K Helix-turn-helix XRE-family like proteins
KPLABODI_01004 4.1e-26 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KPLABODI_01005 8.8e-35 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KPLABODI_01006 5.4e-96 S ABC transporter, ATP-binding protein
KPLABODI_01007 2.8e-153 XK27_00670 S ABC transporter
KPLABODI_01009 4.9e-27
KPLABODI_01010 6.1e-93 L COG2826 Transposase and inactivated derivatives, IS30 family
KPLABODI_01011 3.6e-11 N phage tail tape measure protein
KPLABODI_01012 1.1e-57 C Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
KPLABODI_01013 4.5e-40 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPLABODI_01014 5e-182 gpsA 1.1.1.94 I Rossmann-like domain
KPLABODI_01015 2.7e-58 K sequence-specific DNA binding
KPLABODI_01016 8.5e-86
KPLABODI_01017 2.9e-71 F DNA/RNA non-specific endonuclease
KPLABODI_01019 2.6e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPLABODI_01020 1.6e-132 S Core-2/I-Branching enzyme
KPLABODI_01021 2.2e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
KPLABODI_01022 7.7e-151 cps1D M Domain of unknown function (DUF4422)
KPLABODI_01023 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
KPLABODI_01024 2.4e-172 glfT1 1.1.1.133 S Glycosyltransferase like family 2
KPLABODI_01025 1.5e-184 M Glycosyl transferases group 1
KPLABODI_01026 5.1e-198 wbbI M transferase activity, transferring glycosyl groups
KPLABODI_01027 2.1e-263 epsIIL S Membrane protein involved in the export of O-antigen and teichoic acid
KPLABODI_01028 6e-179 M LicD family
KPLABODI_01029 3.4e-85 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
KPLABODI_01030 4.7e-222
KPLABODI_01032 5.6e-41 I Acyltransferase family
KPLABODI_01033 2.1e-18 S Peptidase_C39 like family
KPLABODI_01034 6.2e-09 S Peptidase_C39 like family
KPLABODI_01035 1.1e-49 S Bacterial membrane protein, YfhO
KPLABODI_01036 2.5e-27 I transferase activity, transferring acyl groups other than amino-acyl groups
KPLABODI_01037 1.9e-74 S VanZ like family
KPLABODI_01038 9.4e-74 mesH S Teichoic acid glycosylation protein
KPLABODI_01039 2.2e-128 S VanZ like family
KPLABODI_01040 2.6e-58 sidC L DNA recombination
KPLABODI_01041 6.9e-84 sidC L DNA recombination
KPLABODI_01042 1.3e-10 sidC L DNA recombination
KPLABODI_01043 0.0 3.1.4.46, 3.2.1.99 GH43 N domain, Protein
KPLABODI_01045 2.5e-39
KPLABODI_01046 3.4e-134 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KPLABODI_01047 2e-123 pgm3 G Phosphoglycerate mutase family
KPLABODI_01048 4.5e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KPLABODI_01049 0.0 helD 3.6.4.12 L DNA helicase
KPLABODI_01050 1.6e-25 glnQ 3.6.3.21 E ABC transporter
KPLABODI_01051 5.5e-49 aatB ET ABC transporter substrate-binding protein
KPLABODI_01052 4.7e-85 aatB ET ABC transporter substrate-binding protein
KPLABODI_01053 1.8e-11 liaI S membrane
KPLABODI_01054 2.6e-74 XK27_02470 K LytTr DNA-binding domain
KPLABODI_01055 5.7e-103 E GDSL-like Lipase/Acylhydrolase
KPLABODI_01056 1e-170 coaA 2.7.1.33 F Pantothenic acid kinase
KPLABODI_01057 1.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPLABODI_01058 6.2e-76 ymfM S Helix-turn-helix domain
KPLABODI_01059 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KPLABODI_01060 1.2e-197
KPLABODI_01061 1.4e-14 L the current gene model (or a revised gene model) may contain a frame shift
KPLABODI_01062 2.7e-109 L COG2826 Transposase and inactivated derivatives, IS30 family
KPLABODI_01063 3.3e-289 V ABC transporter transmembrane region
KPLABODI_01064 7.8e-09 S PAS domain
KPLABODI_01065 3.5e-44 GK ROK family
KPLABODI_01068 1.6e-157 dkg S reductase
KPLABODI_01069 3e-124 endA F DNA RNA non-specific endonuclease
KPLABODI_01070 2.6e-42 E dipeptidase activity
KPLABODI_01071 5.7e-106
KPLABODI_01072 5.4e-86 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KPLABODI_01073 4.6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
KPLABODI_01074 6.7e-154 corA P CorA-like Mg2+ transporter protein
KPLABODI_01075 1.7e-157 3.5.2.6 V Beta-lactamase enzyme family
KPLABODI_01076 5.5e-26
KPLABODI_01077 2.3e-99 yobS K Bacterial regulatory proteins, tetR family
KPLABODI_01078 0.0 ydgH S MMPL family
KPLABODI_01079 1.2e-173
KPLABODI_01080 9.7e-203 S Protein of unknown function DUF262
KPLABODI_01081 3.3e-306 N Uncharacterized conserved protein (DUF2075)
KPLABODI_01082 1.6e-77 1.3.5.4 C FAD binding domain
KPLABODI_01083 6.5e-104 1.3.5.4 C FAD binding domain
KPLABODI_01084 2.2e-90 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPLABODI_01085 8.9e-26 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPLABODI_01086 1.4e-137 S Peptidase family M23
KPLABODI_01087 3.1e-80 mutT 3.6.1.55 F NUDIX domain
KPLABODI_01088 2.3e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
KPLABODI_01089 1.8e-150 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KPLABODI_01090 4.1e-138 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KPLABODI_01091 4.4e-88 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KPLABODI_01092 7.3e-23
KPLABODI_01093 5.2e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KPLABODI_01094 9.8e-160 xerD L Phage integrase, N-terminal SAM-like domain
KPLABODI_01095 3.9e-53 S Alpha beta hydrolase
KPLABODI_01096 3.8e-21 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KPLABODI_01097 2.5e-39 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KPLABODI_01098 8.8e-78 L DDE superfamily endonuclease
KPLABODI_01099 5.6e-27 L DDE superfamily endonuclease
KPLABODI_01103 6.8e-49 S Domain of Unknown Function with PDB structure (DUF3862)
KPLABODI_01105 2.6e-123 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KPLABODI_01106 8.1e-126 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KPLABODI_01107 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KPLABODI_01108 1.4e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPLABODI_01109 3.1e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KPLABODI_01110 1.9e-77 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KPLABODI_01111 1e-68 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KPLABODI_01112 3.9e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KPLABODI_01113 6.3e-123 IQ reductase
KPLABODI_01114 7.4e-180 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KPLABODI_01115 1e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPLABODI_01116 8.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPLABODI_01117 1.2e-183 K AI-2E family transporter
KPLABODI_01118 0.0 S Predicted membrane protein (DUF2207)
KPLABODI_01119 5.5e-115 K Bacterial regulatory proteins, tetR family
KPLABODI_01120 0.0 yhcA V ABC transporter, ATP-binding protein
KPLABODI_01121 3.8e-66 S Iron-sulphur cluster biosynthesis
KPLABODI_01122 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPLABODI_01123 2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPLABODI_01124 2.2e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
KPLABODI_01125 4.4e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPLABODI_01127 7.4e-49
KPLABODI_01128 4.6e-227 ywhK S Membrane
KPLABODI_01129 1.3e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
KPLABODI_01130 4.7e-94 S ECF transporter, substrate-specific component
KPLABODI_01131 3.2e-14 S Domain of unknown function (DUF4430)
KPLABODI_01132 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
KPLABODI_01133 4.4e-163 yvgN C Aldo keto reductase
KPLABODI_01134 4.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KPLABODI_01135 2e-80
KPLABODI_01136 1.8e-161 xth 3.1.11.2 L exodeoxyribonuclease III
KPLABODI_01137 8.7e-59 S glycolate biosynthetic process
KPLABODI_01138 1.3e-18 L haloacid dehalogenase-like hydrolase
KPLABODI_01139 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KPLABODI_01140 8.7e-18 L Transposase and inactivated derivatives, IS30 family
KPLABODI_01141 9.5e-153
KPLABODI_01142 7.6e-67 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KPLABODI_01143 7.5e-57 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KPLABODI_01144 1.4e-158 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KPLABODI_01145 3.8e-85 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KPLABODI_01146 2.2e-293 ytgP S Polysaccharide biosynthesis protein
KPLABODI_01147 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPLABODI_01148 6.7e-18 L the current gene model (or a revised gene model) may contain a frame shift
KPLABODI_01149 2.7e-185 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KPLABODI_01150 2.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
KPLABODI_01151 1.7e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KPLABODI_01152 4.4e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KPLABODI_01153 4.7e-171 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPLABODI_01154 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KPLABODI_01155 4.1e-220 patA 2.6.1.1 E Aminotransferase
KPLABODI_01156 5e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPLABODI_01157 2.4e-153 S Protein of unknown function (DUF3298)
KPLABODI_01158 6.5e-99 K Sigma-70 region 2
KPLABODI_01159 5.9e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPLABODI_01160 6.1e-93 J Acetyltransferase (GNAT) domain
KPLABODI_01161 4.4e-106 yjbF S SNARE associated Golgi protein
KPLABODI_01162 7.7e-154 I alpha/beta hydrolase fold
KPLABODI_01163 5.2e-156 hipB K Helix-turn-helix
KPLABODI_01164 8.6e-95 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
KPLABODI_01165 1.2e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
KPLABODI_01166 0.0 lacS G Transporter
KPLABODI_01167 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KPLABODI_01168 6.6e-26 K purine nucleotide biosynthetic process
KPLABODI_01169 6.3e-108 galR K Transcriptional regulator
KPLABODI_01176 7.9e-29 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KPLABODI_01177 5.1e-13 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KPLABODI_01178 1.1e-11 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KPLABODI_01179 1e-193 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KPLABODI_01180 1.4e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KPLABODI_01181 3.5e-142 K LysR family
KPLABODI_01182 2.2e-36 P Sodium:sulfate symporter transmembrane region
KPLABODI_01184 7.8e-202 S amidohydrolase
KPLABODI_01185 1e-13 XK27_07210 6.1.1.6 S B3 4 domain
KPLABODI_01186 2.3e-124 E Arginine ornithine antiporter
KPLABODI_01187 4.2e-82 E amino acid
KPLABODI_01205 3.4e-14 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
KPLABODI_01206 1.2e-62 V ABC-type multidrug transport system, ATPase and permease components
KPLABODI_01207 3.4e-102 V ABC-type multidrug transport system, ATPase and permease components
KPLABODI_01208 6.5e-282 V ABC-type multidrug transport system, ATPase and permease components
KPLABODI_01209 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KPLABODI_01210 1.2e-129
KPLABODI_01211 1.5e-161 cpsY K Transcriptional regulator, LysR family
KPLABODI_01212 6.6e-220 2.1.1.14 E methionine synthase, vitamin-B12 independent
KPLABODI_01213 2.9e-103
KPLABODI_01215 7.3e-172 glk 2.7.1.2 G Glucokinase
KPLABODI_01216 2.4e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KPLABODI_01217 1.3e-221 naiP EGP Major facilitator Superfamily
KPLABODI_01218 2.9e-96 S Membrane
KPLABODI_01219 1.7e-148 ydiN EGP Major Facilitator Superfamily
KPLABODI_01220 1.6e-171 K Transcriptional regulator, LysR family
KPLABODI_01221 0.0 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 C FAD binding domain
KPLABODI_01222 2.5e-166 arbZ I Phosphate acyltransferases
KPLABODI_01223 1.6e-116 arbY M Glycosyl transferase family 8
KPLABODI_01224 3.2e-155 arbx M Glycosyl transferase family 8
KPLABODI_01225 2.2e-150 arbV 2.3.1.51 I Acyl-transferase
KPLABODI_01227 2.6e-132 K response regulator
KPLABODI_01228 0.0 vicK 2.7.13.3 T Histidine kinase
KPLABODI_01229 5e-242 yycH S YycH protein
KPLABODI_01230 4.4e-141 yycI S YycH protein
KPLABODI_01231 8.8e-150 vicX 3.1.26.11 S domain protein
KPLABODI_01232 7.2e-162 htrA 3.4.21.107 O serine protease
KPLABODI_01233 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPLABODI_01237 2.7e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
KPLABODI_01238 1.3e-33 L Transposase and inactivated derivatives, IS30 family
KPLABODI_01239 1.8e-18 L transposase and inactivated derivatives, IS30 family
KPLABODI_01240 1.6e-112 P Cobalt transport protein
KPLABODI_01241 1.4e-251 cbiO1 S ABC transporter, ATP-binding protein
KPLABODI_01242 4.6e-269 emrY EGP Major facilitator Superfamily
KPLABODI_01243 2.2e-151 K helix_turn_helix, arabinose operon control protein
KPLABODI_01244 9.5e-172 natA1 S ABC transporter
KPLABODI_01245 1.6e-108 S ABC-2 family transporter protein
KPLABODI_01246 2.5e-138 S ABC-2 family transporter protein
KPLABODI_01248 1.3e-221 S ATP diphosphatase activity
KPLABODI_01249 1.2e-152 mutR K Helix-turn-helix XRE-family like proteins
KPLABODI_01250 4.4e-150 htpX O Belongs to the peptidase M48B family
KPLABODI_01251 1.6e-94 lemA S LemA family
KPLABODI_01252 5e-207 ybiR P Citrate transporter
KPLABODI_01253 2.8e-16
KPLABODI_01254 2.2e-173 L HNH nucleases
KPLABODI_01255 5e-114 CBM50 M NlpC P60 family protein
KPLABODI_01256 3.5e-140 glnQ E ABC transporter, ATP-binding protein
KPLABODI_01257 1.9e-273 glnP P ABC transporter permease
KPLABODI_01258 9.4e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KPLABODI_01259 3.7e-66 yeaO S Protein of unknown function, DUF488
KPLABODI_01260 4.2e-132 cobB K SIR2 family
KPLABODI_01261 2.3e-81
KPLABODI_01262 5.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPLABODI_01263 5.6e-180 S Alpha/beta hydrolase of unknown function (DUF915)
KPLABODI_01264 5.9e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPLABODI_01265 6.3e-163 ypuA S Protein of unknown function (DUF1002)
KPLABODI_01266 5.7e-160 epsV 2.7.8.12 S glycosyl transferase family 2
KPLABODI_01267 1.1e-124 S Alpha/beta hydrolase family
KPLABODI_01268 4.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPLABODI_01269 1.2e-123 luxT K Bacterial regulatory proteins, tetR family
KPLABODI_01270 1.7e-143
KPLABODI_01271 7.2e-118 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KPLABODI_01272 5.3e-200 S Cysteine-rich secretory protein family
KPLABODI_01273 7.6e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KPLABODI_01274 1.8e-44
KPLABODI_01275 9.9e-184 yibE S overlaps another CDS with the same product name
KPLABODI_01276 4.5e-130 yibF S overlaps another CDS with the same product name
KPLABODI_01277 2.4e-169 I alpha/beta hydrolase fold
KPLABODI_01278 2.8e-17 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
KPLABODI_01279 2.5e-52 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
KPLABODI_01280 1.5e-101 malF P Binding-protein-dependent transport system inner membrane component
KPLABODI_01281 1.3e-143 malG P ABC transporter permease
KPLABODI_01282 0.0 G Belongs to the glycosyl hydrolase 31 family
KPLABODI_01283 1.5e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KPLABODI_01284 3e-89 ntd 2.4.2.6 F Nucleoside
KPLABODI_01285 1.1e-83 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KPLABODI_01286 1.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
KPLABODI_01287 2.5e-83 uspA T universal stress protein
KPLABODI_01288 2.3e-157 phnD P Phosphonate ABC transporter
KPLABODI_01289 3.3e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KPLABODI_01290 7.5e-125 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KPLABODI_01291 1.1e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KPLABODI_01292 3.9e-207 oppA E ABC transporter, substratebinding protein
KPLABODI_01293 7.1e-28 oppA E ABC transporter, substratebinding protein
KPLABODI_01294 6.6e-84
KPLABODI_01295 1.7e-273 S Calcineurin-like phosphoesterase
KPLABODI_01296 0.0 asnB 6.3.5.4 E Asparagine synthase
KPLABODI_01297 7.6e-249 yxbA 6.3.1.12 S ATP-grasp enzyme
KPLABODI_01298 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KPLABODI_01299 3.9e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPLABODI_01300 9.4e-33 S Iron-sulfur cluster assembly protein
KPLABODI_01301 3.7e-49 XK27_04775 S PAS domain
KPLABODI_01302 1.4e-228 yttB EGP Major facilitator Superfamily
KPLABODI_01303 5e-62 Z012_07300 O Glutaredoxin-related protein
KPLABODI_01304 0.0 pepO 3.4.24.71 O Peptidase family M13
KPLABODI_01305 0.0 kup P Transport of potassium into the cell
KPLABODI_01306 1.7e-72
KPLABODI_01307 6.2e-86
KPLABODI_01308 3.4e-29
KPLABODI_01309 4e-34 S Protein of unknown function (DUF2922)
KPLABODI_01310 6.3e-192 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KPLABODI_01311 5.5e-276 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KPLABODI_01312 0.0 yjbQ P TrkA C-terminal domain protein
KPLABODI_01313 9.2e-99 S Oxidoreductase
KPLABODI_01314 2e-132
KPLABODI_01315 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPLABODI_01316 1.7e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPLABODI_01317 2.9e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KPLABODI_01318 0.0 XK27_08315 M Sulfatase
KPLABODI_01319 1.5e-52 S Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
KPLABODI_01320 5.5e-95 L DDE superfamily endonuclease
KPLABODI_01321 1.4e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
KPLABODI_01322 6e-112 papP P ABC transporter, permease protein
KPLABODI_01323 4e-79 P ABC transporter permease
KPLABODI_01324 1.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KPLABODI_01325 2.7e-160 cjaA ET ABC transporter substrate-binding protein
KPLABODI_01328 1.8e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPLABODI_01330 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
KPLABODI_01331 4.8e-86 steT E amino acid
KPLABODI_01332 2.1e-232 amd 3.5.1.47 E Peptidase family M20/M25/M40
KPLABODI_01333 1.6e-243 N Uncharacterized conserved protein (DUF2075)
KPLABODI_01334 3.1e-121 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KPLABODI_01335 4e-19 oppA E ABC transporter, substratebinding protein
KPLABODI_01336 9.1e-62 oppA E ABC transporter, substratebinding protein
KPLABODI_01337 2.3e-173 oppA E ABC transporter, substratebinding protein
KPLABODI_01338 9.4e-292 oppA E ABC transporter, substratebinding protein
KPLABODI_01339 1.9e-30 oppA E transmembrane transport
KPLABODI_01340 3.5e-123 oppA E ABC transporter, substratebinding protein
KPLABODI_01341 1.4e-97 oppA E ABC transporter, substratebinding protein
KPLABODI_01342 3e-301 oppA E ABC transporter
KPLABODI_01343 2.6e-145 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPLABODI_01344 7.8e-183 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPLABODI_01345 3.9e-198 oppD P Belongs to the ABC transporter superfamily
KPLABODI_01346 2.8e-179 oppF P Belongs to the ABC transporter superfamily
KPLABODI_01347 5.1e-256 pepC 3.4.22.40 E aminopeptidase
KPLABODI_01348 6.5e-259 pepC 3.4.22.40 E Papain family cysteine protease
KPLABODI_01349 2.1e-73 hsp O Belongs to the small heat shock protein (HSP20) family
KPLABODI_01350 2.1e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPLABODI_01351 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KPLABODI_01352 3.1e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KPLABODI_01353 8e-145 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
KPLABODI_01354 1.7e-96 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
KPLABODI_01355 2.1e-61
KPLABODI_01356 2.1e-225 pbuX F xanthine permease
KPLABODI_01357 1.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KPLABODI_01358 3.1e-204 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KPLABODI_01359 2.4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KPLABODI_01360 3.4e-39 S HicA toxin of bacterial toxin-antitoxin,
KPLABODI_01361 5.8e-64 S HicB family
KPLABODI_01362 1.9e-233 KLT Protein kinase domain
KPLABODI_01363 5.7e-169 KLT Protein kinase domain
KPLABODI_01364 3.2e-284 V ABC-type multidrug transport system, ATPase and permease components
KPLABODI_01365 1.4e-142 K Transcriptional regulator
KPLABODI_01366 1.6e-242 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPLABODI_01368 1.1e-15 S Psort location Cytoplasmic, score
KPLABODI_01371 3.8e-132 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KPLABODI_01372 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KPLABODI_01373 1.8e-72 tcyB E ABC transporter
KPLABODI_01374 4.8e-42 tcyB E ABC transporter
KPLABODI_01376 7.4e-130 2.4.2.3 F Phosphorylase superfamily
KPLABODI_01377 2.4e-250 yxbA 6.3.1.12 S ATP-grasp enzyme
KPLABODI_01378 1.2e-166 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KPLABODI_01379 5.8e-20 mmuP E amino acid
KPLABODI_01380 8.6e-156 mmuP E amino acid
KPLABODI_01381 9.2e-175 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KPLABODI_01382 8.6e-78 ywhH S Aminoacyl-tRNA editing domain
KPLABODI_01383 2.8e-07 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Maltose acetyltransferase
KPLABODI_01384 2.1e-76 K DNA-binding transcription factor activity
KPLABODI_01385 4.6e-188 ansA 3.5.1.1 EJ L-asparaginase, type I
KPLABODI_01386 3.8e-47 Q phosphatase activity
KPLABODI_01387 1.1e-92 S Sucrose-6F-phosphate phosphohydrolase
KPLABODI_01388 2.6e-80 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KPLABODI_01389 1.2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPLABODI_01390 6.7e-18 L transposase and inactivated derivatives, IS30 family
KPLABODI_01391 4.2e-91 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KPLABODI_01392 5.5e-137 metQ_4 P Belongs to the nlpA lipoprotein family
KPLABODI_01393 4.2e-74 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KPLABODI_01394 2.4e-259 1.1.3.15 C FAD linked oxidases, C-terminal domain
KPLABODI_01395 6e-188 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPLABODI_01401 1.1e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPLABODI_01402 3.8e-260 mdr EGP Sugar (and other) transporter
KPLABODI_01403 1.3e-119 3.6.1.27 I Acid phosphatase homologues
KPLABODI_01405 4e-74 L Putative transposase DNA-binding domain
KPLABODI_01406 4.1e-248 nhaC C Na H antiporter NhaC
KPLABODI_01407 3.8e-10 G polysaccharide deacetylase
KPLABODI_01408 3e-142 G polysaccharide deacetylase
KPLABODI_01409 1.3e-50 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KPLABODI_01410 5.3e-164 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
KPLABODI_01416 1.1e-185 asnB 6.3.5.4 E Aluminium induced protein
KPLABODI_01417 1.2e-79 asnB 6.3.5.4 E Aluminium induced protein
KPLABODI_01418 1.2e-160 spoU 2.1.1.185 J Methyltransferase
KPLABODI_01419 1.8e-74
KPLABODI_01429 2.5e-17 L the current gene model (or a revised gene model) may contain a frame shift
KPLABODI_01430 3e-24 L Transposase
KPLABODI_01431 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPLABODI_01432 4.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KPLABODI_01433 7.4e-32 S Uncharacterised protein family (UPF0236)
KPLABODI_01434 3.9e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KPLABODI_01435 7e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KPLABODI_01436 8.4e-54 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
KPLABODI_01437 1.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KPLABODI_01438 5.5e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPLABODI_01439 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPLABODI_01440 4.8e-42 rplGA J ribosomal protein
KPLABODI_01441 4.3e-43 ylxR K Protein of unknown function (DUF448)
KPLABODI_01442 6.8e-194 nusA K Participates in both transcription termination and antitermination
KPLABODI_01443 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
KPLABODI_01444 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPLABODI_01445 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KPLABODI_01446 4.3e-228 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KPLABODI_01447 1.1e-144 cdsA 2.7.7.41 S Belongs to the CDS family
KPLABODI_01448 7.6e-124 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KPLABODI_01449 2.9e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KPLABODI_01450 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KPLABODI_01451 5.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPLABODI_01452 1.1e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
KPLABODI_01453 7.1e-189 yabB 2.1.1.223 L Methyltransferase small domain
KPLABODI_01454 1.4e-115 plsC 2.3.1.51 I Acyltransferase
KPLABODI_01455 4.8e-182 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPLABODI_01456 1.3e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
KPLABODI_01457 3.6e-213 hom 1.1.1.3 E homoserine dehydrogenase
KPLABODI_01458 2.6e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
KPLABODI_01459 0.0 mdlB V ABC transporter
KPLABODI_01460 0.0 mdlA V ABC transporter
KPLABODI_01461 2.3e-31 yneF S Uncharacterised protein family (UPF0154)
KPLABODI_01462 8.9e-34 ynzC S UPF0291 protein
KPLABODI_01463 3.5e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KPLABODI_01464 6e-149 glcU U ribose uptake protein RbsU
KPLABODI_01465 9.6e-145 glnH ET ABC transporter substrate-binding protein
KPLABODI_01466 3.4e-97
KPLABODI_01467 0.0 lhr L DEAD DEAH box helicase
KPLABODI_01468 3.4e-247 P P-loop Domain of unknown function (DUF2791)
KPLABODI_01469 0.0 S TerB-C domain
KPLABODI_01470 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
KPLABODI_01471 5.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KPLABODI_01472 0.0 snf 2.7.11.1 KL domain protein
KPLABODI_01473 1.8e-09 CP_1020 S Psort location Cytoplasmic, score 8.87
KPLABODI_01474 1.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KPLABODI_01475 1.5e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPLABODI_01476 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KPLABODI_01477 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPLABODI_01478 8.6e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KPLABODI_01479 1.5e-73 pipD E Dipeptidase
KPLABODI_01480 1.1e-07 pipD E Dipeptidase
KPLABODI_01481 1.7e-15 pipD E Dipeptidase
KPLABODI_01483 7.5e-154 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KPLABODI_01484 0.0 smc D Required for chromosome condensation and partitioning
KPLABODI_01485 3.1e-127 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KPLABODI_01486 0.0 oppA E ABC transporter substrate-binding protein
KPLABODI_01487 0.0 oppA1 E ABC transporter substrate-binding protein
KPLABODI_01488 5.5e-156 oppC P Binding-protein-dependent transport system inner membrane component
KPLABODI_01489 1.3e-176 oppB P ABC transporter permease
KPLABODI_01490 2.4e-178 oppF P Belongs to the ABC transporter superfamily
KPLABODI_01491 1.4e-189 oppD P Belongs to the ABC transporter superfamily
KPLABODI_01492 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPLABODI_01493 7.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KPLABODI_01494 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KPLABODI_01495 1.6e-278 yloV S DAK2 domain fusion protein YloV
KPLABODI_01496 8.8e-57 asp S Asp23 family, cell envelope-related function
KPLABODI_01497 3.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KPLABODI_01498 3e-279 V ABC transporter transmembrane region
KPLABODI_01501 1.8e-30 D nuclear chromosome segregation
KPLABODI_01503 1.4e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
KPLABODI_01504 1.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KPLABODI_01505 0.0 KLT serine threonine protein kinase
KPLABODI_01506 4.3e-138 stp 3.1.3.16 T phosphatase
KPLABODI_01507 4.1e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPLABODI_01508 1.1e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPLABODI_01509 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPLABODI_01510 2.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KPLABODI_01511 1.1e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KPLABODI_01512 2.6e-49
KPLABODI_01513 3.2e-33 oppA E transmembrane transport
KPLABODI_01514 2.9e-14 oppA E ABC transporter, substratebinding protein
KPLABODI_01515 1.6e-46 oppA E transmembrane transport
KPLABODI_01516 1.4e-306 recN L May be involved in recombinational repair of damaged DNA
KPLABODI_01517 7.8e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KPLABODI_01518 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KPLABODI_01519 1.7e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPLABODI_01520 8e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPLABODI_01521 3.7e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPLABODI_01522 1.8e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPLABODI_01523 8.1e-73 yqhY S Asp23 family, cell envelope-related function
KPLABODI_01524 2.4e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPLABODI_01525 1.1e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KPLABODI_01526 2.1e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KPLABODI_01527 9.9e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KPLABODI_01528 3.9e-65 arsC 1.20.4.1 P Belongs to the ArsC family
KPLABODI_01529 4e-90 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KPLABODI_01530 2.6e-60 livF E ABC transporter
KPLABODI_01531 3.1e-242 purD 6.3.4.13 F Belongs to the GARS family
KPLABODI_01532 4.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KPLABODI_01533 1.4e-109 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KPLABODI_01534 4.6e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KPLABODI_01535 6.6e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KPLABODI_01536 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPLABODI_01537 5.2e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPLABODI_01538 2.8e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPLABODI_01539 1.6e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KPLABODI_01540 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPLABODI_01541 1.6e-210 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KPLABODI_01542 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPLABODI_01543 4.8e-41 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
KPLABODI_01544 4.2e-119 EGP Major Facilitator Superfamily
KPLABODI_01545 5.4e-98 P nitrite transmembrane transporter activity
KPLABODI_01546 1e-234
KPLABODI_01547 1.3e-308 S SH3-like domain
KPLABODI_01548 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KPLABODI_01550 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KPLABODI_01551 1.3e-216 EGP Major facilitator Superfamily
KPLABODI_01552 5e-150 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KPLABODI_01553 4.7e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KPLABODI_01554 6.1e-74 L DDE superfamily endonuclease
KPLABODI_01555 3e-24 L Transposase
KPLABODI_01556 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KPLABODI_01557 8e-205 pepO 3.4.24.71 O Peptidase family M13
KPLABODI_01558 8.5e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KPLABODI_01559 7.7e-58
KPLABODI_01560 1.2e-85 L DDE superfamily endonuclease
KPLABODI_01566 3.1e-39 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KPLABODI_01567 6.8e-25 L DDE superfamily endonuclease
KPLABODI_01568 1e-184 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KPLABODI_01569 6.6e-119 dedA S SNARE-like domain protein
KPLABODI_01570 3.5e-106 S Protein of unknown function (DUF1461)
KPLABODI_01571 3.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KPLABODI_01572 2.8e-83 yutD S Protein of unknown function (DUF1027)
KPLABODI_01573 5.6e-280 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KPLABODI_01574 5.6e-58
KPLABODI_01575 4.9e-182 ccpA K catabolite control protein A
KPLABODI_01576 1.8e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KPLABODI_01578 1.4e-27 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KPLABODI_01579 1.7e-39
KPLABODI_01580 5.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KPLABODI_01581 2.7e-149 ykuT M mechanosensitive ion channel
KPLABODI_01582 2.3e-113 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KPLABODI_01583 1.7e-66 yslB S Protein of unknown function (DUF2507)
KPLABODI_01584 1e-53 trxA O Belongs to the thioredoxin family
KPLABODI_01585 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KPLABODI_01586 1e-40 yrzB S Belongs to the UPF0473 family
KPLABODI_01587 3.9e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPLABODI_01588 5.7e-42 yrzL S Belongs to the UPF0297 family
KPLABODI_01589 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPLABODI_01590 7.5e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KPLABODI_01591 4.1e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KPLABODI_01592 6.4e-207 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPLABODI_01593 6.6e-281 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KPLABODI_01594 3e-34 yajC U Preprotein translocase
KPLABODI_01595 1.6e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KPLABODI_01596 6.4e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KPLABODI_01597 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPLABODI_01598 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KPLABODI_01599 1.8e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KPLABODI_01600 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPLABODI_01601 1e-122 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPLABODI_01602 6.8e-302 uup S ABC transporter, ATP-binding protein
KPLABODI_01603 7.6e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KPLABODI_01604 7.7e-94 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KPLABODI_01605 3.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KPLABODI_01606 2e-89 folT S ECF transporter, substrate-specific component
KPLABODI_01607 3.4e-89 folT S ECF transporter, substrate-specific component
KPLABODI_01608 3.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
KPLABODI_01609 8.6e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPLABODI_01610 9.9e-55 yabA L Involved in initiation control of chromosome replication
KPLABODI_01611 1e-159 holB 2.7.7.7 L DNA polymerase III
KPLABODI_01612 2.4e-53 yaaQ S Cyclic-di-AMP receptor
KPLABODI_01613 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPLABODI_01614 1.4e-34 S Protein of unknown function (DUF2508)
KPLABODI_01615 1.5e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPLABODI_01616 3.5e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KPLABODI_01617 7.1e-288 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPLABODI_01618 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KPLABODI_01619 7.2e-112 rsmC 2.1.1.172 J Methyltransferase
KPLABODI_01620 1.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPLABODI_01621 9.1e-173
KPLABODI_01622 1.2e-45
KPLABODI_01623 1.9e-14 L Helix-turn-helix domain
KPLABODI_01624 4.6e-205 pbpX1 V Beta-lactamase
KPLABODI_01625 4.2e-214 pbpX1 V Beta-lactamase
KPLABODI_01626 1.6e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KPLABODI_01627 3e-19 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
KPLABODI_01628 3.8e-11 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
KPLABODI_01630 3.3e-83 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPLABODI_01631 4.6e-14 P nitric oxide dioxygenase activity
KPLABODI_01632 1.6e-145 oppA E ABC transporter, substratebinding protein
KPLABODI_01633 1.4e-84 oppA E ABC transporter, substratebinding protein
KPLABODI_01634 1.8e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KPLABODI_01635 1.1e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPLABODI_01636 5.9e-206 L Putative transposase DNA-binding domain
KPLABODI_01637 8.5e-69
KPLABODI_01638 1.6e-230 amtB P ammonium transporter
KPLABODI_01639 2.9e-190 S Glycosyl transferase family 2
KPLABODI_01640 2e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KPLABODI_01641 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPLABODI_01642 5.2e-101 nusG K Participates in transcription elongation, termination and antitermination
KPLABODI_01643 1.8e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KPLABODI_01644 1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KPLABODI_01645 6.7e-50 dxs 2.2.1.7 HI 1-deoxy-D-xylulose-5-phosphate synthase
KPLABODI_01646 2.9e-96 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPLABODI_01647 9.1e-95 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPLABODI_01648 1.4e-112 4.2.99.20 S Alpha/beta hydrolase family
KPLABODI_01649 1.8e-33
KPLABODI_01650 2.4e-101 yvrI K sigma factor activity
KPLABODI_01651 5.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPLABODI_01652 9.4e-77 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KPLABODI_01653 1.1e-275 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPLABODI_01654 2.7e-105 3.6.1.67 F NUDIX domain
KPLABODI_01655 1.2e-160 K LysR substrate binding domain
KPLABODI_01656 7.2e-181 yeiH S Conserved hypothetical protein 698
KPLABODI_01657 3.3e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPLABODI_01659 1.7e-120 skfE V ATPases associated with a variety of cellular activities
KPLABODI_01660 8.7e-60 yvoA_1 K Transcriptional regulator, GntR family
KPLABODI_01661 4.2e-264 oppA E ABC transporter, substratebinding protein
KPLABODI_01662 1.1e-92 3.6.1.13 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KPLABODI_01663 4.8e-232 6.3.2.4 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KPLABODI_01664 9.7e-180 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
KPLABODI_01665 9.4e-26 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
KPLABODI_01666 8.5e-159 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPLABODI_01667 8.6e-201
KPLABODI_01668 3.2e-212 EGP Transmembrane secretion effector
KPLABODI_01669 2.7e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KPLABODI_01670 7.1e-71 2.7.13.3 T diguanylate cyclase
KPLABODI_01671 2.5e-28 5.99.1.2 T diguanylate cyclase
KPLABODI_01672 1.5e-109 T EAL domain
KPLABODI_01673 4.8e-11 5.99.1.2 T diguanylate cyclase
KPLABODI_01674 3.7e-85 S ECF-type riboflavin transporter, S component
KPLABODI_01675 6.7e-262 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
KPLABODI_01676 4.4e-144 cbiQ P cobalt transport
KPLABODI_01677 0.0 ykoD P ABC transporter, ATP-binding protein
KPLABODI_01678 1.3e-99 S UPF0397 protein
KPLABODI_01679 7.6e-160 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
KPLABODI_01680 1.5e-253 cycA E Amino acid permease
KPLABODI_01681 0.0 S ABC-type transport system involved in multi-copper enzyme maturation permease component
KPLABODI_01682 1.2e-168 ytrB V ABC transporter
KPLABODI_01683 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
KPLABODI_01690 1.3e-66 E Methionine synthase
KPLABODI_01691 2.3e-237 EK Aminotransferase, class I
KPLABODI_01692 2.8e-168 K LysR substrate binding domain
KPLABODI_01693 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KPLABODI_01694 1e-76 argR K Regulates arginine biosynthesis genes
KPLABODI_01695 3.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPLABODI_01696 2.1e-207 S Amidohydrolase
KPLABODI_01697 2.5e-175 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPLABODI_01698 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KPLABODI_01699 3.2e-183 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
KPLABODI_01700 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KPLABODI_01701 8.1e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KPLABODI_01702 0.0 oatA I Acyltransferase
KPLABODI_01703 3.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KPLABODI_01704 4.5e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KPLABODI_01705 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KPLABODI_01706 2e-307 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KPLABODI_01707 0.0 L SNF2 family N-terminal domain
KPLABODI_01708 3.7e-63
KPLABODI_01710 3.2e-98 ywlG S Belongs to the UPF0340 family
KPLABODI_01711 1.9e-15 gmuR K UTRA
KPLABODI_01712 4.4e-55 gmuR K UbiC transcription regulator-associated domain protein
KPLABODI_01713 7.6e-89 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPLABODI_01714 4.3e-29 S Protein of unknown function (DUF2929)
KPLABODI_01715 0.0 dnaE 2.7.7.7 L DNA polymerase
KPLABODI_01716 2e-180 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KPLABODI_01717 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KPLABODI_01718 5.9e-39 ssuB P anion transmembrane transporter activity
KPLABODI_01720 1e-88 I Acyltransferase family
KPLABODI_01721 4e-164 cvfB S S1 domain
KPLABODI_01722 5.4e-164 xerD D recombinase XerD
KPLABODI_01723 8.9e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPLABODI_01724 6e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPLABODI_01725 3.4e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPLABODI_01726 9.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPLABODI_01727 3.9e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPLABODI_01729 5e-108 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KPLABODI_01730 3.2e-212 rpsA 1.17.7.4 J Ribosomal protein S1
KPLABODI_01731 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KPLABODI_01732 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KPLABODI_01733 3.9e-229 S Tetratricopeptide repeat protein
KPLABODI_01734 0.0 S Bacterial membrane protein YfhO
KPLABODI_01735 4.7e-171 K LysR substrate binding domain
KPLABODI_01736 1.3e-111 K DNA-binding transcription factor activity
KPLABODI_01737 3.4e-26
KPLABODI_01738 5.2e-16
KPLABODI_01739 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPLABODI_01740 7e-71
KPLABODI_01742 4.5e-204 argH 2.3.1.1, 4.3.2.1 E argininosuccinate lyase
KPLABODI_01744 5e-18
KPLABODI_01746 0.0 cas3 L CRISPR-associated helicase cas3
KPLABODI_01747 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
KPLABODI_01748 1.8e-107 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
KPLABODI_01749 1.3e-180 casC L CT1975-like protein
KPLABODI_01750 1.6e-131 casD S CRISPR-associated protein (Cas_Cas5)
KPLABODI_01751 6.9e-118 casE S CRISPR_assoc
KPLABODI_01752 1.2e-174 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KPLABODI_01753 1e-159 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
KPLABODI_01754 1.2e-109 2.7.6.5 T Region found in RelA / SpoT proteins
KPLABODI_01755 7.4e-118 K response regulator
KPLABODI_01756 6.7e-229 sptS 2.7.13.3 T Histidine kinase
KPLABODI_01757 1.3e-196 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KPLABODI_01758 2.8e-216 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KPLABODI_01759 4.8e-221 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KPLABODI_01760 2.2e-225 yjjP S Putative threonine/serine exporter
KPLABODI_01761 1.1e-89 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPLABODI_01762 4.2e-175 prmA J Ribosomal protein L11 methyltransferase
KPLABODI_01763 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KPLABODI_01764 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KPLABODI_01765 2.3e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
KPLABODI_01766 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KPLABODI_01767 4e-12
KPLABODI_01768 1.3e-24 L DDE superfamily endonuclease
KPLABODI_01769 6.2e-48 L COG3547 Transposase and inactivated derivatives
KPLABODI_01771 8.4e-10 L COG3547 Transposase and inactivated derivatives
KPLABODI_01773 1.4e-98 repA S Replication initiator protein A
KPLABODI_01774 3.2e-21 U Relaxase/Mobilisation nuclease domain
KPLABODI_01775 5.2e-93 mdt(A) EGP Major facilitator Superfamily
KPLABODI_01776 0.0 copB 3.6.3.4 P P-type ATPase
KPLABODI_01777 2.4e-37 celA 3.2.1.86 GT1 G beta-glucosidase activity
KPLABODI_01778 4e-30 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPLABODI_01779 1.1e-203 K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPLABODI_01780 6.2e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KPLABODI_01781 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KPLABODI_01782 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KPLABODI_01783 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KPLABODI_01784 6.7e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KPLABODI_01785 6.8e-136 recO L Involved in DNA repair and RecF pathway recombination
KPLABODI_01786 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KPLABODI_01787 2.9e-75 cdd 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KPLABODI_01788 6.7e-98 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KPLABODI_01789 1.3e-171 phoH T phosphate starvation-inducible protein PhoH
KPLABODI_01790 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KPLABODI_01791 1.5e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KPLABODI_01793 3.8e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPLABODI_01796 1.5e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KPLABODI_01797 3.4e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KPLABODI_01800 4e-175 lacX 5.1.3.3 G Aldose 1-epimerase
KPLABODI_01801 2.4e-243 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KPLABODI_01802 4e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KPLABODI_01803 1.8e-164 xerC D Phage integrase, N-terminal SAM-like domain
KPLABODI_01804 6.8e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KPLABODI_01805 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPLABODI_01806 2e-152 dprA LU DNA protecting protein DprA
KPLABODI_01807 4.4e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPLABODI_01808 7.4e-163 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPLABODI_01809 5.5e-36 yozE S Belongs to the UPF0346 family
KPLABODI_01810 3.3e-155 DegV S Uncharacterised protein, DegV family COG1307
KPLABODI_01811 4.8e-117 hlyIII S protein, hemolysin III
KPLABODI_01812 4.1e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KPLABODI_01813 4.3e-169 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPLABODI_01814 1.8e-07 yliE T Putative diguanylate phosphodiesterase
KPLABODI_01815 3e-09 yliE T EAL domain
KPLABODI_01816 1.2e-09 yliE T Putative diguanylate phosphodiesterase
KPLABODI_01818 0.0 XK27_10035 V ABC transporter
KPLABODI_01819 5.3e-309 yfiB1 V ABC transporter, ATP-binding protein
KPLABODI_01820 4.1e-164 lysR7 K LysR substrate binding domain
KPLABODI_01821 1.2e-157
KPLABODI_01822 6.1e-97 3.6.1.27 I Acid phosphatase homologues
KPLABODI_01823 9.8e-152 yitS S Uncharacterised protein, DegV family COG1307
KPLABODI_01824 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KPLABODI_01825 2.6e-53 S Protein of unknown function (DUF2752)
KPLABODI_01826 1.5e-181 yjgN S Bacterial protein of unknown function (DUF898)
KPLABODI_01827 1.6e-103 S Protein of unknown function (DUF4230)
KPLABODI_01828 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KPLABODI_01829 1.1e-259 glnPH2 P ABC transporter permease
KPLABODI_01830 2.4e-161 lysR5 K LysR substrate binding domain
KPLABODI_01831 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
KPLABODI_01832 1.2e-103 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPLABODI_01833 6.8e-14 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPLABODI_01834 1.2e-184 S AI-2E family transporter
KPLABODI_01835 5.3e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KPLABODI_01836 5.9e-155 czcD P cation diffusion facilitator family transporter
KPLABODI_01837 2.5e-49 K DNA-binding transcription factor activity
KPLABODI_01838 9.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPLABODI_01839 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KPLABODI_01840 2.1e-123 srtA 3.4.22.70 M sortase family
KPLABODI_01841 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KPLABODI_01842 1.7e-170 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KPLABODI_01843 0.0 dnaK O Heat shock 70 kDa protein
KPLABODI_01844 5.7e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KPLABODI_01845 8.7e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KPLABODI_01846 6.8e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KPLABODI_01847 9.9e-100 sip L Belongs to the 'phage' integrase family
KPLABODI_01848 3.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KPLABODI_01849 1.9e-139 manY G PTS system
KPLABODI_01850 3.9e-170 manN G system, mannose fructose sorbose family IID component
KPLABODI_01851 1.6e-63 manO S Domain of unknown function (DUF956)
KPLABODI_01853 8.6e-246 cycA E Amino acid permease
KPLABODI_01854 2.5e-163 3.5.2.6 M NlpC/P60 family
KPLABODI_01856 1.6e-07 K Helix-turn-helix domain
KPLABODI_01857 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPLABODI_01858 0.0 recQ1 L Helicase conserved C-terminal domain
KPLABODI_01859 2.4e-47
KPLABODI_01860 7.8e-19 K sequence-specific DNA binding
KPLABODI_01862 1.7e-221 oxlT P Major Facilitator Superfamily
KPLABODI_01863 3.7e-21 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
KPLABODI_01864 4.6e-99 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
KPLABODI_01865 4.9e-72 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
KPLABODI_01867 1.4e-161 L COG2826 Transposase and inactivated derivatives, IS30 family
KPLABODI_01868 1.1e-207 G Major Facilitator Superfamily
KPLABODI_01869 2.9e-38 L COG2963 Transposase and inactivated derivatives
KPLABODI_01870 2.9e-205 G Major Facilitator Superfamily
KPLABODI_01871 6.4e-31 L Transposase and inactivated derivatives, IS30 family
KPLABODI_01872 1e-276 E Amino acid permease
KPLABODI_01873 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KPLABODI_01874 6.2e-81 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
KPLABODI_01875 6.5e-127 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
KPLABODI_01876 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KPLABODI_01877 2.1e-199 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KPLABODI_01878 7.8e-79 2.7.1.199, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KPLABODI_01879 1.4e-159 scrB 3.2.1.26 GH32 G invertase
KPLABODI_01880 3.2e-138 scrR K Transcriptional regulator, LacI family
KPLABODI_01881 7.7e-25
KPLABODI_01882 1.5e-106 yiiE S Protein of unknown function (DUF1211)
KPLABODI_01883 7.2e-100 K Acetyltransferase (GNAT) domain
KPLABODI_01887 1.2e-282 thrC 4.2.3.1 E Threonine synthase
KPLABODI_01888 7.2e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KPLABODI_01892 2.7e-83 M LysM domain protein
KPLABODI_01893 9.5e-145 D nuclear chromosome segregation
KPLABODI_01894 8e-252 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
KPLABODI_01895 3.4e-08 lacR K DeoR C terminal sensor domain
KPLABODI_01896 1.4e-165 cycA E Amino acid permease
KPLABODI_01897 1.7e-47 cycA E Amino acid permease
KPLABODI_01898 1.4e-275 pepV 3.5.1.18 E dipeptidase PepV
KPLABODI_01899 1.8e-136 ybbH_2 K Helix-turn-helix domain, rpiR family
KPLABODI_01900 1e-18 3.5.2.6 V Beta-lactamase
KPLABODI_01901 7.5e-08 3.5.2.6 V Beta-lactamase
KPLABODI_01902 4.8e-196 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KPLABODI_01903 1.7e-93 wecD K Acetyltransferase (GNAT) family
KPLABODI_01904 1e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KPLABODI_01905 8.5e-115 S membrane transporter protein
KPLABODI_01906 4.7e-128 pgm3 G Belongs to the phosphoglycerate mutase family
KPLABODI_01907 2.6e-28
KPLABODI_01908 5.2e-29
KPLABODI_01909 2.2e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPLABODI_01910 2.1e-79 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KPLABODI_01911 7e-183 S AAA domain
KPLABODI_01912 8.1e-57 5.2.1.8 O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
KPLABODI_01913 3.2e-51 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KPLABODI_01914 2.1e-32 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KPLABODI_01916 1.7e-70 V AAA domain (dynein-related subfamily)
KPLABODI_01917 2.1e-44 S LlaJI restriction endonuclease
KPLABODI_01918 5.6e-266 pepC 3.4.22.40 E Peptidase C1-like family
KPLABODI_01919 5.4e-49
KPLABODI_01920 1.7e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KPLABODI_01921 6.6e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPLABODI_01922 9e-186 arbY M Glycosyl transferase family 8
KPLABODI_01923 7.8e-64 yliE T domain protein
KPLABODI_01924 2.1e-149 yliE T Putative diguanylate phosphodiesterase
KPLABODI_01925 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KPLABODI_01926 4e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPLABODI_01927 2.6e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPLABODI_01928 1.4e-62 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KPLABODI_01929 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KPLABODI_01930 3e-243 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPLABODI_01931 5.3e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KPLABODI_01932 2.2e-37 yaaA S S4 domain protein YaaA
KPLABODI_01933 2.2e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPLABODI_01934 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPLABODI_01935 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPLABODI_01936 5.1e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KPLABODI_01937 1.4e-88 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KPLABODI_01938 3.3e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KPLABODI_01939 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KPLABODI_01940 1.5e-74 rplI J Binds to the 23S rRNA
KPLABODI_01941 9.8e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KPLABODI_01942 7.5e-227 MA20_36090 S Protein of unknown function (DUF2974)
KPLABODI_01943 0.0 V ATPases associated with a variety of cellular activities
KPLABODI_01944 1.1e-68
KPLABODI_01946 5.8e-121 yhiD S MgtC family
KPLABODI_01948 3.3e-73 V ABC-type multidrug transport system, ATPase and permease components
KPLABODI_01949 1.4e-114 V ABC-type multidrug transport system, ATPase and permease components
KPLABODI_01950 1.4e-139 K LytTr DNA-binding domain
KPLABODI_01951 1.2e-191 2.7.13.3 T GHKL domain
KPLABODI_01953 5.4e-25
KPLABODI_01954 8.6e-304 msbA2 3.6.3.44 V ABC transporter
KPLABODI_01955 0.0 KLT Protein kinase domain
KPLABODI_01956 1e-20
KPLABODI_01958 2e-112 ybbL S ABC transporter, ATP-binding protein
KPLABODI_01959 2.3e-131 ybbM S Uncharacterised protein family (UPF0014)
KPLABODI_01960 3.3e-10
KPLABODI_01961 7.6e-240 lysA2 M Glycosyl hydrolases family 25
KPLABODI_01962 9.4e-11 K Acetyltransferase (GNAT) domain
KPLABODI_01963 9.5e-29 K Acetyltransferase (GNAT) domain
KPLABODI_01964 4.5e-93 L Psort location Cytoplasmic, score 8.87
KPLABODI_01965 1.2e-14 L Transposase
KPLABODI_01967 2e-152 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KPLABODI_01968 2.9e-91 S ECF-type riboflavin transporter, S component
KPLABODI_01969 0.0 L Helicase C-terminal domain protein
KPLABODI_01970 4.1e-98 T integral membrane protein
KPLABODI_01971 2.3e-84 S YcxB-like protein
KPLABODI_01972 1.4e-72 K Transcriptional regulator
KPLABODI_01974 3e-56 qorB 1.6.5.2 GM NmrA-like family
KPLABODI_01975 1.3e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)