ORF_ID e_value Gene_name EC_number CAZy COGs Description
LOHBLHCF_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LOHBLHCF_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LOHBLHCF_00003 2.4e-33 yaaA S S4 domain
LOHBLHCF_00004 9.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LOHBLHCF_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
LOHBLHCF_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOHBLHCF_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOHBLHCF_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_00011 4.3e-180 yaaC S YaaC-like Protein
LOHBLHCF_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LOHBLHCF_00013 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LOHBLHCF_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LOHBLHCF_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LOHBLHCF_00016 8.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LOHBLHCF_00017 1.3e-09
LOHBLHCF_00018 8.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
LOHBLHCF_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
LOHBLHCF_00020 2e-212 yaaH M Glycoside Hydrolase Family
LOHBLHCF_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
LOHBLHCF_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LOHBLHCF_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOHBLHCF_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LOHBLHCF_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LOHBLHCF_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
LOHBLHCF_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
LOHBLHCF_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
LOHBLHCF_00032 1.1e-75 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LOHBLHCF_00033 4.9e-202 yaaN P Belongs to the TelA family
LOHBLHCF_00034 2.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LOHBLHCF_00035 6.9e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LOHBLHCF_00036 2.2e-54 yaaQ S protein conserved in bacteria
LOHBLHCF_00037 1.5e-71 yaaR S protein conserved in bacteria
LOHBLHCF_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
LOHBLHCF_00039 6.1e-146 yaaT S stage 0 sporulation protein
LOHBLHCF_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
LOHBLHCF_00041 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
LOHBLHCF_00042 7.3e-49 yazA L endonuclease containing a URI domain
LOHBLHCF_00043 5.1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LOHBLHCF_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
LOHBLHCF_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOHBLHCF_00046 1.2e-143 tatD L hydrolase, TatD
LOHBLHCF_00047 2e-167 rpfB GH23 T protein conserved in bacteria
LOHBLHCF_00048 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LOHBLHCF_00049 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LOHBLHCF_00050 1.2e-136 yabG S peptidase
LOHBLHCF_00051 7.8e-39 veg S protein conserved in bacteria
LOHBLHCF_00052 8.3e-27 sspF S DNA topological change
LOHBLHCF_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LOHBLHCF_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LOHBLHCF_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LOHBLHCF_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LOHBLHCF_00057 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LOHBLHCF_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOHBLHCF_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LOHBLHCF_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LOHBLHCF_00061 2.4e-39 yabK S Peptide ABC transporter permease
LOHBLHCF_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LOHBLHCF_00063 1.5e-92 spoVT K stage V sporulation protein
LOHBLHCF_00064 2.5e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOHBLHCF_00065 5.6e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LOHBLHCF_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LOHBLHCF_00067 1.5e-49 yabP S Sporulation protein YabP
LOHBLHCF_00068 4e-105 yabQ S spore cortex biosynthesis protein
LOHBLHCF_00069 1.1e-44 divIC D Septum formation initiator
LOHBLHCF_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
LOHBLHCF_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
LOHBLHCF_00074 2.9e-123 yabS S protein containing a von Willebrand factor type A (vWA) domain
LOHBLHCF_00075 3.7e-185 KLT serine threonine protein kinase
LOHBLHCF_00076 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LOHBLHCF_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LOHBLHCF_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LOHBLHCF_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LOHBLHCF_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LOHBLHCF_00081 3.4e-158 yacD 5.2.1.8 O peptidyl-prolyl isomerase
LOHBLHCF_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LOHBLHCF_00083 4.8e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LOHBLHCF_00084 2.8e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
LOHBLHCF_00085 6.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
LOHBLHCF_00086 6.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LOHBLHCF_00087 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LOHBLHCF_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LOHBLHCF_00089 4.1e-30 yazB K transcriptional
LOHBLHCF_00090 3.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOHBLHCF_00091 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LOHBLHCF_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_00097 2e-08
LOHBLHCF_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_00103 2.9e-76 ctsR K Belongs to the CtsR family
LOHBLHCF_00104 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
LOHBLHCF_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LOHBLHCF_00106 0.0 clpC O Belongs to the ClpA ClpB family
LOHBLHCF_00107 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LOHBLHCF_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LOHBLHCF_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
LOHBLHCF_00110 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LOHBLHCF_00111 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LOHBLHCF_00112 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LOHBLHCF_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
LOHBLHCF_00114 1.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LOHBLHCF_00115 2.3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LOHBLHCF_00116 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOHBLHCF_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
LOHBLHCF_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
LOHBLHCF_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LOHBLHCF_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
LOHBLHCF_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LOHBLHCF_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LOHBLHCF_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LOHBLHCF_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LOHBLHCF_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
LOHBLHCF_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOHBLHCF_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOHBLHCF_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
LOHBLHCF_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LOHBLHCF_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LOHBLHCF_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LOHBLHCF_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LOHBLHCF_00133 2.4e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
LOHBLHCF_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LOHBLHCF_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LOHBLHCF_00136 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
LOHBLHCF_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LOHBLHCF_00138 3.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LOHBLHCF_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LOHBLHCF_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LOHBLHCF_00141 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LOHBLHCF_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LOHBLHCF_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LOHBLHCF_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LOHBLHCF_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LOHBLHCF_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LOHBLHCF_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LOHBLHCF_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LOHBLHCF_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LOHBLHCF_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LOHBLHCF_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LOHBLHCF_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LOHBLHCF_00153 1.9e-23 rpmD J Ribosomal protein L30
LOHBLHCF_00154 1.8e-72 rplO J binds to the 23S rRNA
LOHBLHCF_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LOHBLHCF_00156 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LOHBLHCF_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
LOHBLHCF_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LOHBLHCF_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LOHBLHCF_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LOHBLHCF_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LOHBLHCF_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOHBLHCF_00163 3.6e-58 rplQ J Ribosomal protein L17
LOHBLHCF_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOHBLHCF_00165 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOHBLHCF_00166 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOHBLHCF_00167 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LOHBLHCF_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LOHBLHCF_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LOHBLHCF_00170 9.3e-113 sip L Belongs to the 'phage' integrase family
LOHBLHCF_00171 4e-61 E IrrE N-terminal-like domain
LOHBLHCF_00172 1.4e-53 K Cro/C1-type HTH DNA-binding domain
LOHBLHCF_00173 6e-20
LOHBLHCF_00174 8.1e-23
LOHBLHCF_00176 1.8e-19
LOHBLHCF_00177 1.7e-81
LOHBLHCF_00178 4.5e-21 S Uncharacterized protein YqaH
LOHBLHCF_00180 2.4e-93 S DNA protection
LOHBLHCF_00181 2e-161 tadZ D AAA domain
LOHBLHCF_00182 4.6e-76 S Protein of unknown function (DUF669)
LOHBLHCF_00183 0.0 S D5 N terminal like
LOHBLHCF_00185 4.2e-69
LOHBLHCF_00186 2.1e-94 S ERCC4 domain
LOHBLHCF_00188 1.9e-48
LOHBLHCF_00190 2.2e-58
LOHBLHCF_00191 9.1e-49
LOHBLHCF_00192 1.3e-08
LOHBLHCF_00193 5.7e-17 S HNH endonuclease
LOHBLHCF_00195 1.2e-53 terS L Terminase, small subunit
LOHBLHCF_00196 4.2e-149 terL S Terminase
LOHBLHCF_00198 1.5e-172 S portal protein
LOHBLHCF_00199 1.1e-72 pi136 S Caudovirus prohead serine protease
LOHBLHCF_00200 1.7e-128 S capsid protein
LOHBLHCF_00201 2.1e-08
LOHBLHCF_00202 1.5e-22 S Phage gp6-like head-tail connector protein
LOHBLHCF_00203 1.3e-27 S Phage head-tail joining protein
LOHBLHCF_00204 1.1e-28 S Bacteriophage HK97-gp10, putative tail-component
LOHBLHCF_00205 1.1e-10
LOHBLHCF_00206 9.6e-29 S Phage tail tube protein
LOHBLHCF_00209 2.8e-230 D Phage tail tape measure protein
LOHBLHCF_00210 7.2e-46 S Phage tail protein
LOHBLHCF_00211 7.2e-110 mur1 NU Prophage endopeptidase tail
LOHBLHCF_00212 1.3e-58
LOHBLHCF_00213 6.3e-55 S Domain of unknown function (DUF2479)
LOHBLHCF_00215 3.2e-11 S Phage uncharacterised protein (Phage_XkdX)
LOHBLHCF_00216 1.4e-58 S Bacteriophage holin family
LOHBLHCF_00217 3.7e-139 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
LOHBLHCF_00218 9.4e-25
LOHBLHCF_00219 6.4e-38
LOHBLHCF_00221 7.1e-08
LOHBLHCF_00222 4.5e-143 ybaJ Q Methyltransferase domain
LOHBLHCF_00223 6.3e-65 ybaK S Protein of unknown function (DUF2521)
LOHBLHCF_00224 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOHBLHCF_00225 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LOHBLHCF_00226 1.2e-84 gerD
LOHBLHCF_00227 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
LOHBLHCF_00228 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
LOHBLHCF_00229 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_00232 2e-08
LOHBLHCF_00236 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_00237 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_00238 1.6e-247 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
LOHBLHCF_00239 3e-160 ybaS 1.1.1.58 S Na -dependent transporter
LOHBLHCF_00240 2.5e-56 ybbA S Putative esterase
LOHBLHCF_00241 1.4e-118 aacC 2.3.1.81 V aminoglycoside
LOHBLHCF_00242 7e-47 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
LOHBLHCF_00243 5.9e-50 2.7.7.73, 2.7.7.80 H ThiF family
LOHBLHCF_00244 1.6e-45
LOHBLHCF_00245 2.6e-63 S Major Facilitator Superfamily
LOHBLHCF_00246 2e-56 1.14.11.27 S JmjC domain, hydroxylase
LOHBLHCF_00247 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_00248 6.9e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_00249 4e-165 feuA P Iron-uptake system-binding protein
LOHBLHCF_00250 4.2e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
LOHBLHCF_00251 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
LOHBLHCF_00252 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
LOHBLHCF_00253 4.3e-250 yfeW 3.4.16.4 V Belongs to the UPF0214 family
LOHBLHCF_00254 2.2e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOHBLHCF_00255 1.2e-149 ybbH K transcriptional
LOHBLHCF_00256 5.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LOHBLHCF_00257 1.9e-86 ybbJ J acetyltransferase
LOHBLHCF_00258 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
LOHBLHCF_00264 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_00265 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LOHBLHCF_00266 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LOHBLHCF_00267 1.5e-224 ybbR S protein conserved in bacteria
LOHBLHCF_00268 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LOHBLHCF_00269 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LOHBLHCF_00270 5.5e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LOHBLHCF_00271 3.9e-116 adaA 3.2.2.21 K Transcriptional regulator
LOHBLHCF_00272 9e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LOHBLHCF_00273 5.9e-272 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LOHBLHCF_00274 0.0 ybcC S Belongs to the UPF0753 family
LOHBLHCF_00275 1.7e-93 can 4.2.1.1 P carbonic anhydrase
LOHBLHCF_00277 8.7e-47
LOHBLHCF_00278 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
LOHBLHCF_00279 5.1e-50 ybzH K Helix-turn-helix domain
LOHBLHCF_00280 1.9e-201 ybcL EGP Major facilitator Superfamily
LOHBLHCF_00281 7e-56
LOHBLHCF_00282 5.8e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LOHBLHCF_00283 4.2e-121 T Transcriptional regulatory protein, C terminal
LOHBLHCF_00284 5.9e-172 T His Kinase A (phospho-acceptor) domain
LOHBLHCF_00286 5.1e-139 KLT Protein tyrosine kinase
LOHBLHCF_00287 3.8e-151 ybdN
LOHBLHCF_00288 3.6e-216 ybdO S Domain of unknown function (DUF4885)
LOHBLHCF_00289 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
LOHBLHCF_00290 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
LOHBLHCF_00291 4.1e-29 ybxH S Family of unknown function (DUF5370)
LOHBLHCF_00292 2.6e-149 ybxI 3.5.2.6 V beta-lactamase
LOHBLHCF_00293 2.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
LOHBLHCF_00294 4.9e-41 ybyB
LOHBLHCF_00295 1.8e-290 ybeC E amino acid
LOHBLHCF_00296 9.3e-161 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LOHBLHCF_00297 7.3e-258 glpT G -transporter
LOHBLHCF_00298 1.5e-34 S Protein of unknown function (DUF2651)
LOHBLHCF_00299 3.3e-169 ybfA 3.4.15.5 K FR47-like protein
LOHBLHCF_00300 2.1e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
LOHBLHCF_00301 6.3e-160 ybfH EG EamA-like transporter family
LOHBLHCF_00302 2.3e-145 msmR K AraC-like ligand binding domain
LOHBLHCF_00303 5.2e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LOHBLHCF_00304 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
LOHBLHCF_00306 2.3e-167 S Alpha/beta hydrolase family
LOHBLHCF_00307 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LOHBLHCF_00308 2.7e-85 ybfM S SNARE associated Golgi protein
LOHBLHCF_00309 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LOHBLHCF_00310 4.6e-45 ybfN
LOHBLHCF_00311 3.4e-255 S Erythromycin esterase
LOHBLHCF_00312 3.9e-192 yceA S Belongs to the UPF0176 family
LOHBLHCF_00313 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOHBLHCF_00314 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOHBLHCF_00315 9.8e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LOHBLHCF_00316 3.2e-127 K UTRA
LOHBLHCF_00318 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LOHBLHCF_00319 2.8e-260 mmuP E amino acid
LOHBLHCF_00320 4.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
LOHBLHCF_00321 2.5e-256 agcS E Sodium alanine symporter
LOHBLHCF_00322 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
LOHBLHCF_00323 4.7e-228 phoQ 2.7.13.3 T Histidine kinase
LOHBLHCF_00324 2.2e-168 glnL T Regulator
LOHBLHCF_00325 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
LOHBLHCF_00326 1.2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOHBLHCF_00327 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
LOHBLHCF_00328 5.2e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LOHBLHCF_00329 1.5e-124 ycbG K FCD
LOHBLHCF_00330 6.6e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
LOHBLHCF_00331 2.3e-178 ycbJ S Macrolide 2'-phosphotransferase
LOHBLHCF_00332 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
LOHBLHCF_00333 4.2e-167 eamA1 EG spore germination
LOHBLHCF_00334 2.5e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_00335 1.9e-167 T PhoQ Sensor
LOHBLHCF_00336 5e-165 ycbN V ABC transporter, ATP-binding protein
LOHBLHCF_00337 5.1e-114 S ABC-2 family transporter protein
LOHBLHCF_00338 8.2e-53 ycbP S Protein of unknown function (DUF2512)
LOHBLHCF_00339 2.2e-78 sleB 3.5.1.28 M Cell wall
LOHBLHCF_00340 2.5e-135 ycbR T vWA found in TerF C terminus
LOHBLHCF_00341 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
LOHBLHCF_00342 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LOHBLHCF_00343 5.8e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LOHBLHCF_00344 6.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LOHBLHCF_00345 1.8e-201 ycbU E Selenocysteine lyase
LOHBLHCF_00346 5.8e-229 lmrB EGP the major facilitator superfamily
LOHBLHCF_00347 1.6e-100 yxaF K Transcriptional regulator
LOHBLHCF_00348 6.9e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LOHBLHCF_00349 1.3e-66 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LOHBLHCF_00350 7.4e-39 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LOHBLHCF_00351 2.3e-55 S RDD family
LOHBLHCF_00352 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
LOHBLHCF_00353 8.9e-157 2.7.13.3 T GHKL domain
LOHBLHCF_00354 1.2e-126 lytR_2 T LytTr DNA-binding domain
LOHBLHCF_00355 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
LOHBLHCF_00356 2.7e-200 natB CP ABC-2 family transporter protein
LOHBLHCF_00357 1.7e-22 yccK C Aldo keto reductase
LOHBLHCF_00358 1e-142 yccK C Aldo keto reductase
LOHBLHCF_00359 6.6e-177 ycdA S Domain of unknown function (DUF5105)
LOHBLHCF_00360 9.8e-269 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_00361 1.9e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_00362 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
LOHBLHCF_00363 2.7e-173 S response regulator aspartate phosphatase
LOHBLHCF_00364 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
LOHBLHCF_00365 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LOHBLHCF_00366 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
LOHBLHCF_00367 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LOHBLHCF_00368 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LOHBLHCF_00369 1.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOHBLHCF_00370 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
LOHBLHCF_00371 1.1e-104 yceD T proteins involved in stress response, homologs of TerZ and
LOHBLHCF_00372 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
LOHBLHCF_00373 6.3e-137 terC P Protein of unknown function (DUF475)
LOHBLHCF_00374 0.0 yceG S Putative component of 'biosynthetic module'
LOHBLHCF_00375 2e-192 yceH P Belongs to the TelA family
LOHBLHCF_00376 4.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
LOHBLHCF_00377 1.2e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
LOHBLHCF_00378 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
LOHBLHCF_00379 5.1e-229 proV 3.6.3.32 E glycine betaine
LOHBLHCF_00380 1.3e-127 opuAB P glycine betaine
LOHBLHCF_00381 5.3e-164 opuAC E glycine betaine
LOHBLHCF_00382 5e-215 amhX S amidohydrolase
LOHBLHCF_00383 1.2e-255 ycgA S Membrane
LOHBLHCF_00384 4.1e-81 ycgB
LOHBLHCF_00385 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
LOHBLHCF_00386 7.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LOHBLHCF_00387 5.2e-290 lctP C L-lactate permease
LOHBLHCF_00388 3.6e-261 mdr EGP Major facilitator Superfamily
LOHBLHCF_00389 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
LOHBLHCF_00390 6.8e-113 ycgF E Lysine exporter protein LysE YggA
LOHBLHCF_00391 9.2e-149 yqcI S YqcI/YcgG family
LOHBLHCF_00392 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
LOHBLHCF_00393 2.4e-112 ycgI S Domain of unknown function (DUF1989)
LOHBLHCF_00394 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LOHBLHCF_00395 9.5e-109 tmrB S AAA domain
LOHBLHCF_00396 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LOHBLHCF_00397 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
LOHBLHCF_00398 4.3e-175 oxyR3 K LysR substrate binding domain
LOHBLHCF_00399 1.5e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LOHBLHCF_00400 2.9e-145 ycgL S Predicted nucleotidyltransferase
LOHBLHCF_00401 5.1e-170 ycgM E Proline dehydrogenase
LOHBLHCF_00402 3.6e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LOHBLHCF_00403 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOHBLHCF_00404 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
LOHBLHCF_00405 2.6e-147 ycgQ S membrane
LOHBLHCF_00406 1.2e-139 ycgR S permeases
LOHBLHCF_00407 7.2e-158 I alpha/beta hydrolase fold
LOHBLHCF_00408 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LOHBLHCF_00409 2.7e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LOHBLHCF_00410 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
LOHBLHCF_00411 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LOHBLHCF_00412 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOHBLHCF_00413 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
LOHBLHCF_00414 1.8e-194 nasA P COG2223 Nitrate nitrite transporter
LOHBLHCF_00415 2.1e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
LOHBLHCF_00416 4.7e-108 yciB M ErfK YbiS YcfS YnhG
LOHBLHCF_00417 2e-227 yciC S GTPases (G3E family)
LOHBLHCF_00418 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
LOHBLHCF_00419 4e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LOHBLHCF_00421 3.9e-51 yckD S Protein of unknown function (DUF2680)
LOHBLHCF_00422 4.1e-45 K MarR family
LOHBLHCF_00423 9.3e-24
LOHBLHCF_00424 2.7e-121 S AAA domain
LOHBLHCF_00425 1.2e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOHBLHCF_00426 6.5e-69 nin S Competence protein J (ComJ)
LOHBLHCF_00427 1.1e-69 nucA M Deoxyribonuclease NucA/NucB
LOHBLHCF_00428 1.5e-186 tlpC 2.7.13.3 NT chemotaxis protein
LOHBLHCF_00429 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
LOHBLHCF_00430 1.1e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
LOHBLHCF_00431 1.3e-63 hxlR K transcriptional
LOHBLHCF_00432 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOHBLHCF_00433 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOHBLHCF_00434 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
LOHBLHCF_00435 5.7e-140 srfAD Q thioesterase
LOHBLHCF_00436 4e-226 EGP Major Facilitator Superfamily
LOHBLHCF_00437 1.3e-86 S YcxB-like protein
LOHBLHCF_00438 5.8e-161 ycxC EG EamA-like transporter family
LOHBLHCF_00439 3.3e-250 ycxD K GntR family transcriptional regulator
LOHBLHCF_00440 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
LOHBLHCF_00441 9.7e-115 yczE S membrane
LOHBLHCF_00442 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LOHBLHCF_00443 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
LOHBLHCF_00444 2e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LOHBLHCF_00445 1.9e-161 bsdA K LysR substrate binding domain
LOHBLHCF_00446 8.3e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LOHBLHCF_00447 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LOHBLHCF_00448 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
LOHBLHCF_00449 6.6e-41 yclD
LOHBLHCF_00450 6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
LOHBLHCF_00451 9.2e-262 dtpT E amino acid peptide transporter
LOHBLHCF_00452 4.6e-292 yclG M Pectate lyase superfamily protein
LOHBLHCF_00454 7.8e-278 gerKA EG Spore germination protein
LOHBLHCF_00455 4e-226 gerKC S spore germination
LOHBLHCF_00456 3.5e-197 gerKB F Spore germination protein
LOHBLHCF_00457 7.3e-121 yclH P ABC transporter
LOHBLHCF_00458 6.2e-202 yclI V ABC transporter (permease) YclI
LOHBLHCF_00459 1e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_00460 4.9e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LOHBLHCF_00461 2e-70 S aspartate phosphatase
LOHBLHCF_00465 1.1e-240 lysC 2.7.2.4 E Belongs to the aspartokinase family
LOHBLHCF_00466 7.7e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_00467 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_00468 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LOHBLHCF_00469 4.7e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
LOHBLHCF_00470 3.2e-251 ycnB EGP Major facilitator Superfamily
LOHBLHCF_00471 6.5e-154 ycnC K Transcriptional regulator
LOHBLHCF_00472 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
LOHBLHCF_00473 4.7e-45 ycnE S Monooxygenase
LOHBLHCF_00474 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
LOHBLHCF_00475 3.9e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOHBLHCF_00476 6.3e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LOHBLHCF_00477 6.4e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOHBLHCF_00478 6.1e-149 glcU U Glucose uptake
LOHBLHCF_00479 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_00480 2.9e-100 ycnI S protein conserved in bacteria
LOHBLHCF_00481 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
LOHBLHCF_00482 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
LOHBLHCF_00483 2.6e-53
LOHBLHCF_00484 4.8e-239 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
LOHBLHCF_00485 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LOHBLHCF_00486 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
LOHBLHCF_00487 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LOHBLHCF_00488 1.3e-08 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LOHBLHCF_00489 3.2e-74 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LOHBLHCF_00490 9.1e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
LOHBLHCF_00491 3.9e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
LOHBLHCF_00493 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LOHBLHCF_00494 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
LOHBLHCF_00495 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LOHBLHCF_00496 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
LOHBLHCF_00497 1.2e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
LOHBLHCF_00498 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LOHBLHCF_00499 1.2e-132 kipR K Transcriptional regulator
LOHBLHCF_00500 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
LOHBLHCF_00502 3.1e-49 yczJ S biosynthesis
LOHBLHCF_00503 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
LOHBLHCF_00504 2.4e-172 ydhF S Oxidoreductase
LOHBLHCF_00505 0.0 mtlR K transcriptional regulator, MtlR
LOHBLHCF_00506 2.1e-293 ydaB IQ acyl-CoA ligase
LOHBLHCF_00507 5.3e-99 ydaC Q Methyltransferase domain
LOHBLHCF_00508 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_00509 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
LOHBLHCF_00510 2.4e-98 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LOHBLHCF_00511 7.6e-76 ydaG 1.4.3.5 S general stress protein
LOHBLHCF_00512 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LOHBLHCF_00513 2.5e-46 ydzA EGP Major facilitator Superfamily
LOHBLHCF_00514 2.5e-74 lrpC K Transcriptional regulator
LOHBLHCF_00515 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOHBLHCF_00516 2.2e-204 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
LOHBLHCF_00517 9.4e-150 ydaK T Diguanylate cyclase, GGDEF domain
LOHBLHCF_00518 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
LOHBLHCF_00519 4.5e-233 ydaM M Glycosyl transferase family group 2
LOHBLHCF_00520 0.0 ydaN S Bacterial cellulose synthase subunit
LOHBLHCF_00521 0.0 ydaO E amino acid
LOHBLHCF_00522 2.5e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LOHBLHCF_00523 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LOHBLHCF_00525 1.8e-27
LOHBLHCF_00526 1.8e-72 sdpB S Protein conserved in bacteria
LOHBLHCF_00528 2.1e-39
LOHBLHCF_00529 3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
LOHBLHCF_00531 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
LOHBLHCF_00532 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
LOHBLHCF_00534 8.9e-59 ydbB G Cupin domain
LOHBLHCF_00535 2.7e-39 ydbC S Domain of unknown function (DUF4937
LOHBLHCF_00536 7.9e-154 ydbD P Catalase
LOHBLHCF_00537 9.6e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LOHBLHCF_00538 9.6e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LOHBLHCF_00539 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
LOHBLHCF_00540 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOHBLHCF_00541 9.7e-181 ydbI S AI-2E family transporter
LOHBLHCF_00542 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
LOHBLHCF_00543 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LOHBLHCF_00544 2.7e-52 ydbL
LOHBLHCF_00545 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LOHBLHCF_00546 1.1e-18 S Fur-regulated basic protein B
LOHBLHCF_00547 2.2e-07 S Fur-regulated basic protein A
LOHBLHCF_00548 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOHBLHCF_00549 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LOHBLHCF_00550 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LOHBLHCF_00551 3.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LOHBLHCF_00552 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LOHBLHCF_00553 2.1e-82 ydbS S Bacterial PH domain
LOHBLHCF_00554 1.1e-259 ydbT S Membrane
LOHBLHCF_00555 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
LOHBLHCF_00556 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LOHBLHCF_00557 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
LOHBLHCF_00558 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LOHBLHCF_00559 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LOHBLHCF_00560 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
LOHBLHCF_00561 1.3e-143 rsbR T Positive regulator of sigma-B
LOHBLHCF_00562 5.2e-57 rsbS T antagonist
LOHBLHCF_00563 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LOHBLHCF_00564 7.1e-189 rsbU 3.1.3.3 KT phosphatase
LOHBLHCF_00565 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
LOHBLHCF_00566 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LOHBLHCF_00567 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOHBLHCF_00568 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
LOHBLHCF_00569 0.0 yhgF K COG2183 Transcriptional accessory protein
LOHBLHCF_00570 8.9e-83 ydcK S Belongs to the SprT family
LOHBLHCF_00578 3.2e-114 yecA E amino acid
LOHBLHCF_00579 4.6e-107 K Transcriptional regulator
LOHBLHCF_00580 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
LOHBLHCF_00581 1.2e-43
LOHBLHCF_00582 5e-142 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LOHBLHCF_00583 5.6e-34 K Helix-turn-helix XRE-family like proteins
LOHBLHCF_00584 1.9e-40
LOHBLHCF_00588 7e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LOHBLHCF_00589 8.7e-30 cspL K Cold shock
LOHBLHCF_00590 2.3e-78 carD K Transcription factor
LOHBLHCF_00591 1.6e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LOHBLHCF_00592 5.8e-163 rhaS5 K AraC-like ligand binding domain
LOHBLHCF_00593 2.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LOHBLHCF_00594 6.9e-164 ydeE K AraC family transcriptional regulator
LOHBLHCF_00595 1.8e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOHBLHCF_00596 6.3e-19 ydeG EGP Major facilitator superfamily
LOHBLHCF_00597 2.6e-184 ydeG EGP Major facilitator superfamily
LOHBLHCF_00598 2.7e-45 ydeH
LOHBLHCF_00599 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
LOHBLHCF_00600 1e-111
LOHBLHCF_00601 1e-151 ydeK EG -transporter
LOHBLHCF_00602 4.6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOHBLHCF_00603 6e-73 maoC I N-terminal half of MaoC dehydratase
LOHBLHCF_00604 1.2e-103 ydeN S Serine hydrolase
LOHBLHCF_00605 3e-56 K HxlR-like helix-turn-helix
LOHBLHCF_00606 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LOHBLHCF_00607 8.2e-57 arsR K transcriptional
LOHBLHCF_00608 2.8e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LOHBLHCF_00609 2.9e-142 ydfB J GNAT acetyltransferase
LOHBLHCF_00610 2.3e-149 ydfC EG EamA-like transporter family
LOHBLHCF_00611 6.2e-271 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOHBLHCF_00612 8.9e-185 gadB 4.1.1.105, 4.1.1.28, 4.1.1.29 E Pyridoxal-dependent decarboxylase conserved domain
LOHBLHCF_00613 5e-116 ydfE S Flavin reductase like domain
LOHBLHCF_00614 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
LOHBLHCF_00615 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LOHBLHCF_00617 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
LOHBLHCF_00618 3.2e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOHBLHCF_00619 0.0 ydfJ S drug exporters of the RND superfamily
LOHBLHCF_00620 8.5e-117 S Protein of unknown function (DUF554)
LOHBLHCF_00621 1.2e-143 K Bacterial transcription activator, effector binding domain
LOHBLHCF_00622 2.3e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOHBLHCF_00623 3.8e-108 ydfN C nitroreductase
LOHBLHCF_00624 8.9e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
LOHBLHCF_00625 1.2e-62 mhqP S DoxX
LOHBLHCF_00626 1.7e-54 traF CO Thioredoxin
LOHBLHCF_00627 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
LOHBLHCF_00628 1.3e-29
LOHBLHCF_00630 8.4e-80 ydfR S Protein of unknown function (DUF421)
LOHBLHCF_00631 1.5e-121 ydfS S Protein of unknown function (DUF421)
LOHBLHCF_00632 1.7e-67 cotP O Belongs to the small heat shock protein (HSP20) family
LOHBLHCF_00633 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
LOHBLHCF_00634 2.5e-32 ydgB S Spore germination protein gerPA/gerPF
LOHBLHCF_00635 1e-97 K Bacterial regulatory proteins, tetR family
LOHBLHCF_00636 2.1e-52 S DoxX-like family
LOHBLHCF_00637 1.6e-82 yycN 2.3.1.128 K Acetyltransferase
LOHBLHCF_00638 3.5e-302 expZ S ABC transporter
LOHBLHCF_00639 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
LOHBLHCF_00640 1.2e-88 dinB S DinB family
LOHBLHCF_00641 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
LOHBLHCF_00642 0.0 ydgH S drug exporters of the RND superfamily
LOHBLHCF_00643 1e-113 drgA C nitroreductase
LOHBLHCF_00644 7.1e-69 ydgJ K Winged helix DNA-binding domain
LOHBLHCF_00645 6.3e-208 tcaB EGP Major facilitator Superfamily
LOHBLHCF_00646 3.5e-121 ydhB S membrane transporter protein
LOHBLHCF_00647 2.5e-121 ydhC K FCD
LOHBLHCF_00648 6.3e-243 ydhD M Glycosyl hydrolase
LOHBLHCF_00649 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LOHBLHCF_00650 1.5e-124
LOHBLHCF_00651 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LOHBLHCF_00652 1.6e-66 frataxin S Domain of unknown function (DU1801)
LOHBLHCF_00654 2.8e-82 K Acetyltransferase (GNAT) domain
LOHBLHCF_00655 4.9e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LOHBLHCF_00656 2.3e-96 ydhK M Protein of unknown function (DUF1541)
LOHBLHCF_00657 1e-199 pbuE EGP Major facilitator Superfamily
LOHBLHCF_00658 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
LOHBLHCF_00659 9.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
LOHBLHCF_00660 1.3e-235 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOHBLHCF_00661 1.4e-280 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOHBLHCF_00662 3.7e-131 ydhQ K UTRA
LOHBLHCF_00663 6.8e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
LOHBLHCF_00664 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
LOHBLHCF_00665 2e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
LOHBLHCF_00666 2.3e-156 ydhU P Catalase
LOHBLHCF_00669 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_00670 7.8e-08
LOHBLHCF_00672 9.3e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LOHBLHCF_00673 2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
LOHBLHCF_00674 3.8e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
LOHBLHCF_00675 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LOHBLHCF_00676 1.1e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LOHBLHCF_00677 0.0 ydiF S ABC transporter
LOHBLHCF_00678 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LOHBLHCF_00679 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LOHBLHCF_00680 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LOHBLHCF_00681 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LOHBLHCF_00682 2.9e-27 ydiK S Domain of unknown function (DUF4305)
LOHBLHCF_00683 2.3e-128 ydiL S CAAX protease self-immunity
LOHBLHCF_00684 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LOHBLHCF_00685 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LOHBLHCF_00686 1.2e-227 L Belongs to the 'phage' integrase family
LOHBLHCF_00687 1.7e-111 3.4.21.88 K Peptidase S24-like
LOHBLHCF_00688 1.2e-33 cro K Helix-turn-helix XRE-family like proteins
LOHBLHCF_00690 7.8e-100 S DNA binding
LOHBLHCF_00691 5.3e-31
LOHBLHCF_00694 1.8e-19
LOHBLHCF_00695 1.7e-81
LOHBLHCF_00696 4.5e-21 S Uncharacterized protein YqaH
LOHBLHCF_00698 2.4e-93 S DNA protection
LOHBLHCF_00699 2e-161 tadZ D AAA domain
LOHBLHCF_00700 4.6e-76 S Protein of unknown function (DUF669)
LOHBLHCF_00701 0.0 S D5 N terminal like
LOHBLHCF_00703 2.3e-75
LOHBLHCF_00704 7.1e-95 S ERCC4 domain
LOHBLHCF_00706 2.6e-81
LOHBLHCF_00707 6.5e-15 S YopX protein
LOHBLHCF_00710 2.2e-58
LOHBLHCF_00714 2.7e-69 S HNH endonuclease
LOHBLHCF_00716 4.6e-70 S Phage terminase, small subunit
LOHBLHCF_00717 1.6e-217 S Phage Terminase
LOHBLHCF_00718 2.9e-10
LOHBLHCF_00719 3.9e-213 S Phage portal protein
LOHBLHCF_00720 2.3e-105 S peptidase activity
LOHBLHCF_00721 3.2e-180 S capsid protein
LOHBLHCF_00723 2.1e-27 S peptidoglycan catabolic process
LOHBLHCF_00724 1.7e-25 S Phage gp6-like head-tail connector protein
LOHBLHCF_00725 1.6e-48 S Bacteriophage HK97-gp10, putative tail-component
LOHBLHCF_00726 1.1e-30
LOHBLHCF_00727 1.2e-61
LOHBLHCF_00728 7.5e-26
LOHBLHCF_00729 8.2e-10
LOHBLHCF_00730 0.0 S peptidoglycan catabolic process
LOHBLHCF_00731 1.2e-112 S Phage tail protein
LOHBLHCF_00732 1.8e-245 NU Prophage endopeptidase tail
LOHBLHCF_00733 4.8e-61
LOHBLHCF_00736 3.8e-55 S Domain of unknown function (DUF2479)
LOHBLHCF_00737 7.8e-08
LOHBLHCF_00739 9.3e-58 S Bacteriophage holin family
LOHBLHCF_00740 2.1e-110 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOHBLHCF_00742 2.3e-16 K Helix-turn-helix domain
LOHBLHCF_00743 7.1e-08
LOHBLHCF_00744 5.8e-151 ydjC S Abhydrolase domain containing 18
LOHBLHCF_00745 0.0 K NB-ARC domain
LOHBLHCF_00746 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
LOHBLHCF_00747 9.9e-250 gutA G MFS/sugar transport protein
LOHBLHCF_00748 3.1e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
LOHBLHCF_00749 1.1e-113 pspA KT Phage shock protein A
LOHBLHCF_00750 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOHBLHCF_00751 1.3e-126 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
LOHBLHCF_00752 2.6e-148 ydjI S virion core protein (lumpy skin disease virus)
LOHBLHCF_00753 2.8e-193 S Ion transport 2 domain protein
LOHBLHCF_00754 7.8e-258 iolT EGP Major facilitator Superfamily
LOHBLHCF_00755 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LOHBLHCF_00756 4.5e-64 ydjM M Lytic transglycolase
LOHBLHCF_00757 8e-151 ydjN U Involved in the tonB-independent uptake of proteins
LOHBLHCF_00759 1.4e-34 ydjO S Cold-inducible protein YdjO
LOHBLHCF_00760 2.1e-154 ydjP I Alpha/beta hydrolase family
LOHBLHCF_00761 9.8e-175 yeaA S Protein of unknown function (DUF4003)
LOHBLHCF_00762 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
LOHBLHCF_00763 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
LOHBLHCF_00764 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOHBLHCF_00765 2.7e-177 yeaC S COG0714 MoxR-like ATPases
LOHBLHCF_00766 1.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LOHBLHCF_00767 0.0 yebA E COG1305 Transglutaminase-like enzymes
LOHBLHCF_00768 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LOHBLHCF_00770 4.1e-10
LOHBLHCF_00772 2.8e-212 D Ftsk spoiiie family protein
LOHBLHCF_00773 1.6e-69
LOHBLHCF_00774 7.8e-167 L Replication initiation factor
LOHBLHCF_00775 4e-30 S Domain of unknown function (DUF3173)
LOHBLHCF_00776 2.3e-208 L Phage integrase family
LOHBLHCF_00778 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_00779 4.8e-255 S Domain of unknown function (DUF4179)
LOHBLHCF_00780 1.7e-211 pbuG S permease
LOHBLHCF_00781 1.2e-117 yebC M Membrane
LOHBLHCF_00783 4e-93 yebE S UPF0316 protein
LOHBLHCF_00784 8e-28 yebG S NETI protein
LOHBLHCF_00785 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LOHBLHCF_00786 1.7e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LOHBLHCF_00787 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LOHBLHCF_00788 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LOHBLHCF_00789 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOHBLHCF_00790 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOHBLHCF_00791 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOHBLHCF_00792 4.7e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LOHBLHCF_00793 6.4e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LOHBLHCF_00794 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LOHBLHCF_00795 2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LOHBLHCF_00796 6.5e-232 purD 6.3.4.13 F Belongs to the GARS family
LOHBLHCF_00797 1e-72 K helix_turn_helix ASNC type
LOHBLHCF_00798 3e-229 yjeH E Amino acid permease
LOHBLHCF_00799 2.7e-27 S Protein of unknown function (DUF2892)
LOHBLHCF_00800 0.0 yerA 3.5.4.2 F adenine deaminase
LOHBLHCF_00801 1.8e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
LOHBLHCF_00802 4.8e-51 yerC S protein conserved in bacteria
LOHBLHCF_00803 2.2e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
LOHBLHCF_00805 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LOHBLHCF_00806 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LOHBLHCF_00807 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LOHBLHCF_00808 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
LOHBLHCF_00809 3e-195 yerI S homoserine kinase type II (protein kinase fold)
LOHBLHCF_00810 1.6e-123 sapB S MgtC SapB transporter
LOHBLHCF_00811 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOHBLHCF_00812 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LOHBLHCF_00813 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LOHBLHCF_00814 8.9e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LOHBLHCF_00815 3.4e-144 yerO K Transcriptional regulator
LOHBLHCF_00816 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LOHBLHCF_00817 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LOHBLHCF_00818 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOHBLHCF_00820 3.2e-20
LOHBLHCF_00821 3e-97 L Reverse transcriptase (RNA-dependent DNA polymerase)
LOHBLHCF_00823 0.0 L AAA domain
LOHBLHCF_00824 1.9e-41 S Protein of unknown function, DUF600
LOHBLHCF_00825 1.5e-12 S Protein of unknown function, DUF600
LOHBLHCF_00826 1.7e-55 S Protein of unknown function, DUF600
LOHBLHCF_00827 4.6e-79 S Protein of unknown function, DUF600
LOHBLHCF_00828 3.4e-56 S Protein of unknown function, DUF600
LOHBLHCF_00829 0.0 L nucleic acid phosphodiester bond hydrolysis
LOHBLHCF_00830 4.9e-174 3.4.24.40 CO amine dehydrogenase activity
LOHBLHCF_00831 3e-39
LOHBLHCF_00832 4.1e-209 S Tetratricopeptide repeat
LOHBLHCF_00834 2.7e-126 yeeN K transcriptional regulatory protein
LOHBLHCF_00836 1.8e-99 dhaR3 K Transcriptional regulator
LOHBLHCF_00837 6.9e-80 yesE S SnoaL-like domain
LOHBLHCF_00838 7.1e-150 yesF GM NAD(P)H-binding
LOHBLHCF_00839 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
LOHBLHCF_00840 1.5e-45 cotJB S CotJB protein
LOHBLHCF_00841 5.2e-104 cotJC P Spore Coat
LOHBLHCF_00842 3.3e-100 yesJ K Acetyltransferase (GNAT) family
LOHBLHCF_00844 1.2e-101 yesL S Protein of unknown function, DUF624
LOHBLHCF_00845 0.0 yesM 2.7.13.3 T Histidine kinase
LOHBLHCF_00846 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
LOHBLHCF_00847 9.1e-36 yesO G Bacterial extracellular solute-binding protein
LOHBLHCF_00848 4.4e-194 yesO G Bacterial extracellular solute-binding protein
LOHBLHCF_00849 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
LOHBLHCF_00850 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
LOHBLHCF_00851 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
LOHBLHCF_00852 0.0 yesS K Transcriptional regulator
LOHBLHCF_00853 7.9e-131 E GDSL-like Lipase/Acylhydrolase
LOHBLHCF_00854 5.1e-127 yesU S Domain of unknown function (DUF1961)
LOHBLHCF_00855 1.5e-112 yesV S Protein of unknown function, DUF624
LOHBLHCF_00856 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
LOHBLHCF_00857 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
LOHBLHCF_00858 1.3e-122 yesY E GDSL-like Lipase/Acylhydrolase
LOHBLHCF_00859 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
LOHBLHCF_00860 0.0 yetA
LOHBLHCF_00861 6.9e-289 lplA G Bacterial extracellular solute-binding protein
LOHBLHCF_00862 9.4e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
LOHBLHCF_00863 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
LOHBLHCF_00864 1.7e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LOHBLHCF_00865 5.2e-122 yetF S membrane
LOHBLHCF_00866 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LOHBLHCF_00867 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOHBLHCF_00868 2.4e-34
LOHBLHCF_00869 7.1e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LOHBLHCF_00870 5.8e-19 yezD S Uncharacterized small protein (DUF2292)
LOHBLHCF_00871 5.3e-105 yetJ S Belongs to the BI1 family
LOHBLHCF_00872 1.2e-153 yetK EG EamA-like transporter family
LOHBLHCF_00873 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
LOHBLHCF_00874 1.2e-208 yetM CH FAD binding domain
LOHBLHCF_00875 1.8e-198 yetN S Protein of unknown function (DUF3900)
LOHBLHCF_00876 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LOHBLHCF_00877 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOHBLHCF_00878 3.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
LOHBLHCF_00879 1.9e-172 yfnG 4.2.1.45 M dehydratase
LOHBLHCF_00880 3.2e-180 yfnF M Nucleotide-diphospho-sugar transferase
LOHBLHCF_00881 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
LOHBLHCF_00882 6.2e-187 yfnD M Nucleotide-diphospho-sugar transferase
LOHBLHCF_00883 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
LOHBLHCF_00884 3.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LOHBLHCF_00885 7.9e-239 yfnA E amino acid
LOHBLHCF_00886 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOHBLHCF_00887 1.1e-113 yfmS NT chemotaxis protein
LOHBLHCF_00888 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LOHBLHCF_00889 2.8e-73 yfmQ S Uncharacterised protein from bacillus cereus group
LOHBLHCF_00890 1.4e-69 yfmP K transcriptional
LOHBLHCF_00891 6.2e-208 yfmO EGP Major facilitator Superfamily
LOHBLHCF_00892 1.6e-59 isp O Subtilase family
LOHBLHCF_00893 6.4e-19
LOHBLHCF_00895 6.3e-57
LOHBLHCF_00896 3.5e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LOHBLHCF_00897 4.5e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
LOHBLHCF_00898 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
LOHBLHCF_00899 1.5e-186 yfmJ S N-terminal domain of oxidoreductase
LOHBLHCF_00900 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
LOHBLHCF_00901 1.4e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_00902 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_00903 7.7e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LOHBLHCF_00904 2.9e-24 S Protein of unknown function (DUF3212)
LOHBLHCF_00905 2.2e-57 yflT S Heat induced stress protein YflT
LOHBLHCF_00906 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
LOHBLHCF_00907 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
LOHBLHCF_00908 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LOHBLHCF_00909 2.2e-117 citT T response regulator
LOHBLHCF_00910 1.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
LOHBLHCF_00911 8.5e-227 citM C Citrate transporter
LOHBLHCF_00912 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
LOHBLHCF_00913 5.6e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LOHBLHCF_00914 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LOHBLHCF_00915 1.4e-121 yflK S protein conserved in bacteria
LOHBLHCF_00916 8.9e-18 yflJ S Protein of unknown function (DUF2639)
LOHBLHCF_00917 4.1e-19 yflI
LOHBLHCF_00918 2.4e-50 yflH S Protein of unknown function (DUF3243)
LOHBLHCF_00919 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
LOHBLHCF_00920 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LOHBLHCF_00921 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOHBLHCF_00922 6e-67 yhdN S Domain of unknown function (DUF1992)
LOHBLHCF_00923 2.2e-252 agcS_1 E Sodium alanine symporter
LOHBLHCF_00924 6.4e-25 yfkQ EG Spore germination protein
LOHBLHCF_00925 3.2e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOHBLHCF_00926 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LOHBLHCF_00927 1.8e-133 treR K transcriptional
LOHBLHCF_00928 1.6e-125 yfkO C nitroreductase
LOHBLHCF_00929 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LOHBLHCF_00930 1.1e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
LOHBLHCF_00931 1.2e-206 ydiM EGP Major facilitator Superfamily
LOHBLHCF_00932 2.1e-29 yfkK S Belongs to the UPF0435 family
LOHBLHCF_00933 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOHBLHCF_00934 2.4e-50 yfkI S gas vesicle protein
LOHBLHCF_00935 9.7e-144 yihY S Belongs to the UPF0761 family
LOHBLHCF_00936 5e-08
LOHBLHCF_00937 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
LOHBLHCF_00938 1.8e-182 cax P COG0387 Ca2 H antiporter
LOHBLHCF_00939 4.5e-146 yfkD S YfkD-like protein
LOHBLHCF_00940 6e-149 yfkC M Mechanosensitive ion channel
LOHBLHCF_00941 5.4e-222 yfkA S YfkB-like domain
LOHBLHCF_00942 1.1e-26 yfjT
LOHBLHCF_00943 2.6e-154 pdaA G deacetylase
LOHBLHCF_00944 3.4e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LOHBLHCF_00945 1.7e-184 corA P Mediates influx of magnesium ions
LOHBLHCF_00946 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LOHBLHCF_00947 1.2e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOHBLHCF_00948 3.9e-44 S YfzA-like protein
LOHBLHCF_00949 6.9e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOHBLHCF_00950 7.3e-85 yfjM S Psort location Cytoplasmic, score
LOHBLHCF_00951 1.3e-27 yfjL
LOHBLHCF_00952 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LOHBLHCF_00953 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LOHBLHCF_00954 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LOHBLHCF_00955 3.1e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LOHBLHCF_00956 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
LOHBLHCF_00957 5.8e-25 sspH S Belongs to the SspH family
LOHBLHCF_00958 8.9e-56 yfjF S UPF0060 membrane protein
LOHBLHCF_00959 9.4e-79 S Family of unknown function (DUF5381)
LOHBLHCF_00960 1.8e-101 yfjD S Family of unknown function (DUF5381)
LOHBLHCF_00961 4.1e-144 yfjC
LOHBLHCF_00962 9.2e-191 yfjB
LOHBLHCF_00963 1.1e-44 yfjA S Belongs to the WXG100 family
LOHBLHCF_00964 1.1e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LOHBLHCF_00965 1e-139 glvR K Helix-turn-helix domain, rpiR family
LOHBLHCF_00966 5.2e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOHBLHCF_00967 0.0 yobO M COG5434 Endopolygalacturonase
LOHBLHCF_00968 4.9e-307 yfiB3 V ABC transporter
LOHBLHCF_00969 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOHBLHCF_00970 9.8e-65 mhqP S DoxX
LOHBLHCF_00971 5.3e-161 yfiE 1.13.11.2 S glyoxalase
LOHBLHCF_00972 3.4e-187 yxjM T Histidine kinase
LOHBLHCF_00973 2.8e-109 KT LuxR family transcriptional regulator
LOHBLHCF_00974 1.2e-166 V ABC transporter, ATP-binding protein
LOHBLHCF_00975 2.3e-207 V ABC-2 family transporter protein
LOHBLHCF_00976 9e-204 V COG0842 ABC-type multidrug transport system, permease component
LOHBLHCF_00977 8.3e-99 padR K transcriptional
LOHBLHCF_00978 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LOHBLHCF_00979 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LOHBLHCF_00980 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
LOHBLHCF_00981 5.9e-283 yfiU EGP Major facilitator Superfamily
LOHBLHCF_00982 4.9e-79 yfiV K transcriptional
LOHBLHCF_00983 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LOHBLHCF_00984 8.2e-174 yfiY P ABC transporter substrate-binding protein
LOHBLHCF_00985 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_00986 8.9e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_00987 5.1e-167 yfhB 5.3.3.17 S PhzF family
LOHBLHCF_00988 3.9e-107 yfhC C nitroreductase
LOHBLHCF_00989 2.1e-25 yfhD S YfhD-like protein
LOHBLHCF_00991 1.2e-171 yfhF S nucleoside-diphosphate sugar epimerase
LOHBLHCF_00992 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
LOHBLHCF_00993 3.7e-51 yfhH S Protein of unknown function (DUF1811)
LOHBLHCF_00995 1.1e-209 yfhI EGP Major facilitator Superfamily
LOHBLHCF_00996 6.2e-20 sspK S reproduction
LOHBLHCF_00997 1.3e-44 yfhJ S WVELL protein
LOHBLHCF_00998 2.4e-87 batE T Bacterial SH3 domain homologues
LOHBLHCF_00999 3.9e-50 yfhL S SdpI/YhfL protein family
LOHBLHCF_01000 8.2e-170 yfhM S Alpha beta hydrolase
LOHBLHCF_01001 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOHBLHCF_01002 0.0 yfhO S Bacterial membrane protein YfhO
LOHBLHCF_01003 1.2e-185 yfhP S membrane-bound metal-dependent
LOHBLHCF_01004 3.3e-210 mutY L A G-specific
LOHBLHCF_01005 6.9e-36 yfhS
LOHBLHCF_01006 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_01007 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
LOHBLHCF_01008 1.1e-47 ygaB S YgaB-like protein
LOHBLHCF_01009 1.3e-104 ygaC J Belongs to the UPF0374 family
LOHBLHCF_01010 3.1e-301 ygaD V ABC transporter
LOHBLHCF_01011 8.7e-180 ygaE S Membrane
LOHBLHCF_01012 8.9e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LOHBLHCF_01013 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
LOHBLHCF_01014 4e-80 perR P Belongs to the Fur family
LOHBLHCF_01015 2.8e-55 ygzB S UPF0295 protein
LOHBLHCF_01016 6.7e-167 ygxA S Nucleotidyltransferase-like
LOHBLHCF_01017 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_01022 7.8e-08
LOHBLHCF_01030 2e-08
LOHBLHCF_01034 5e-142 spo0M S COG4326 Sporulation control protein
LOHBLHCF_01035 1.2e-26
LOHBLHCF_01036 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
LOHBLHCF_01037 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LOHBLHCF_01039 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LOHBLHCF_01040 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LOHBLHCF_01041 8.1e-169 ssuA M Sulfonate ABC transporter
LOHBLHCF_01042 2.7e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LOHBLHCF_01043 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LOHBLHCF_01045 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LOHBLHCF_01046 4.1e-78 ygaO
LOHBLHCF_01047 4.4e-29 K Transcriptional regulator
LOHBLHCF_01049 1.8e-113 yhzB S B3/4 domain
LOHBLHCF_01050 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LOHBLHCF_01051 2.4e-175 yhbB S Putative amidase domain
LOHBLHCF_01052 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LOHBLHCF_01053 1.2e-109 yhbD K Protein of unknown function (DUF4004)
LOHBLHCF_01054 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
LOHBLHCF_01055 2.7e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
LOHBLHCF_01056 0.0 prkA T Ser protein kinase
LOHBLHCF_01057 2.5e-225 yhbH S Belongs to the UPF0229 family
LOHBLHCF_01058 2.2e-76 yhbI K DNA-binding transcription factor activity
LOHBLHCF_01059 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
LOHBLHCF_01060 3.1e-271 yhcA EGP Major facilitator Superfamily
LOHBLHCF_01061 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
LOHBLHCF_01062 2.8e-37 yhcC
LOHBLHCF_01063 2e-55
LOHBLHCF_01064 6.6e-60 yhcF K Transcriptional regulator
LOHBLHCF_01065 4e-122 yhcG V ABC transporter, ATP-binding protein
LOHBLHCF_01066 8.5e-165 yhcH V ABC transporter, ATP-binding protein
LOHBLHCF_01067 1.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LOHBLHCF_01068 1e-30 cspB K Cold-shock protein
LOHBLHCF_01069 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
LOHBLHCF_01070 4.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
LOHBLHCF_01071 1.8e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOHBLHCF_01072 8.3e-78 S Protein of unknown function (DUF2812)
LOHBLHCF_01073 1.2e-49 K Transcriptional regulator PadR-like family
LOHBLHCF_01074 2.1e-39 yhcM
LOHBLHCF_01075 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LOHBLHCF_01076 3.6e-166 yhcP
LOHBLHCF_01077 1.5e-99 yhcQ M Spore coat protein
LOHBLHCF_01078 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
LOHBLHCF_01079 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
LOHBLHCF_01080 4.2e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LOHBLHCF_01081 1.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LOHBLHCF_01082 2.1e-67 yhcU S Family of unknown function (DUF5365)
LOHBLHCF_01083 9.9e-68 yhcV S COG0517 FOG CBS domain
LOHBLHCF_01084 1e-119 yhcW 5.4.2.6 S hydrolase
LOHBLHCF_01085 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LOHBLHCF_01086 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LOHBLHCF_01087 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LOHBLHCF_01088 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LOHBLHCF_01089 3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LOHBLHCF_01090 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LOHBLHCF_01091 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LOHBLHCF_01092 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
LOHBLHCF_01093 2.2e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOHBLHCF_01094 1.6e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
LOHBLHCF_01095 1.2e-38 yhdB S YhdB-like protein
LOHBLHCF_01096 1.8e-53 yhdC S Protein of unknown function (DUF3889)
LOHBLHCF_01097 5.1e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LOHBLHCF_01098 2.3e-75 nsrR K Transcriptional regulator
LOHBLHCF_01099 8.1e-237 ygxB M Conserved TM helix
LOHBLHCF_01100 6.3e-276 ycgB S Stage V sporulation protein R
LOHBLHCF_01101 1.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LOHBLHCF_01102 5.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LOHBLHCF_01103 3.8e-162 citR K Transcriptional regulator
LOHBLHCF_01104 2.2e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
LOHBLHCF_01105 6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_01106 3.4e-250 yhdG E amino acid
LOHBLHCF_01107 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LOHBLHCF_01108 9.4e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOHBLHCF_01109 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOHBLHCF_01110 8.1e-45 yhdK S Sigma-M inhibitor protein
LOHBLHCF_01111 6.6e-201 yhdL S Sigma factor regulator N-terminal
LOHBLHCF_01112 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_01113 3.4e-191 yhdN C Aldo keto reductase
LOHBLHCF_01114 1.5e-109 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LOHBLHCF_01115 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LOHBLHCF_01116 4.1e-74 cueR K transcriptional
LOHBLHCF_01117 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
LOHBLHCF_01118 9.6e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
LOHBLHCF_01119 3.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOHBLHCF_01120 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOHBLHCF_01121 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LOHBLHCF_01123 8.4e-183 yhdY M Mechanosensitive ion channel
LOHBLHCF_01124 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LOHBLHCF_01125 1.9e-147 yheN G deacetylase
LOHBLHCF_01126 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LOHBLHCF_01127 1.7e-225 nhaC C Na H antiporter
LOHBLHCF_01128 1.5e-83 nhaX T Belongs to the universal stress protein A family
LOHBLHCF_01129 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOHBLHCF_01130 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOHBLHCF_01131 3.8e-108 yheG GM NAD(P)H-binding
LOHBLHCF_01132 6.3e-28 sspB S spore protein
LOHBLHCF_01133 1.3e-36 yheE S Family of unknown function (DUF5342)
LOHBLHCF_01134 1.1e-264 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
LOHBLHCF_01135 4.3e-216 yheC HJ YheC/D like ATP-grasp
LOHBLHCF_01136 2.2e-202 yheB S Belongs to the UPF0754 family
LOHBLHCF_01137 9.5e-48 yheA S Belongs to the UPF0342 family
LOHBLHCF_01138 2.9e-204 yhaZ L DNA alkylation repair enzyme
LOHBLHCF_01139 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
LOHBLHCF_01140 1.8e-292 hemZ H coproporphyrinogen III oxidase
LOHBLHCF_01141 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
LOHBLHCF_01142 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
LOHBLHCF_01144 4.2e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
LOHBLHCF_01145 2.4e-26 S YhzD-like protein
LOHBLHCF_01146 2.6e-166 yhaQ S ABC transporter, ATP-binding protein
LOHBLHCF_01147 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
LOHBLHCF_01148 1.3e-224 yhaO L DNA repair exonuclease
LOHBLHCF_01149 0.0 yhaN L AAA domain
LOHBLHCF_01150 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
LOHBLHCF_01151 1.6e-21 yhaL S Sporulation protein YhaL
LOHBLHCF_01152 3.2e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LOHBLHCF_01153 8.7e-90 yhaK S Putative zincin peptidase
LOHBLHCF_01154 2.2e-54 yhaI S Protein of unknown function (DUF1878)
LOHBLHCF_01155 1e-113 hpr K Negative regulator of protease production and sporulation
LOHBLHCF_01156 8.2e-39 yhaH S YtxH-like protein
LOHBLHCF_01157 5.4e-21
LOHBLHCF_01158 3.6e-80 trpP S Tryptophan transporter TrpP
LOHBLHCF_01159 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LOHBLHCF_01160 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LOHBLHCF_01161 2.3e-136 ecsA V transporter (ATP-binding protein)
LOHBLHCF_01162 1.8e-215 ecsB U ABC transporter
LOHBLHCF_01163 1.2e-113 ecsC S EcsC protein family
LOHBLHCF_01164 5.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LOHBLHCF_01165 1.7e-241 yhfA C membrane
LOHBLHCF_01166 1.6e-33 1.15.1.2 C Rubrerythrin
LOHBLHCF_01167 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LOHBLHCF_01168 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LOHBLHCF_01169 1.2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LOHBLHCF_01170 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LOHBLHCF_01171 7.7e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LOHBLHCF_01172 5.4e-101 yhgD K Transcriptional regulator
LOHBLHCF_01173 3e-214 yhgE S YhgE Pip N-terminal domain protein
LOHBLHCF_01174 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOHBLHCF_01175 3.5e-135 yhfC S Putative membrane peptidase family (DUF2324)
LOHBLHCF_01176 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
LOHBLHCF_01177 9.2e-71 3.4.13.21 S ASCH
LOHBLHCF_01178 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOHBLHCF_01179 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LOHBLHCF_01180 6.3e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
LOHBLHCF_01181 1.1e-110 yhfK GM NmrA-like family
LOHBLHCF_01182 1.2e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LOHBLHCF_01183 1.3e-64 yhfM
LOHBLHCF_01184 1e-240 yhfN 3.4.24.84 O Peptidase M48
LOHBLHCF_01185 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
LOHBLHCF_01186 4.3e-77 VY92_01935 K acetyltransferase
LOHBLHCF_01187 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
LOHBLHCF_01188 9e-157 yfmC M Periplasmic binding protein
LOHBLHCF_01189 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LOHBLHCF_01190 2.9e-196 vraB 2.3.1.9 I Belongs to the thiolase family
LOHBLHCF_01191 8.4e-276 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LOHBLHCF_01192 5e-91 bioY S BioY family
LOHBLHCF_01193 1.7e-182 hemAT NT chemotaxis protein
LOHBLHCF_01194 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LOHBLHCF_01195 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_01196 1.3e-32 yhzC S IDEAL
LOHBLHCF_01197 2.1e-108 comK K Competence transcription factor
LOHBLHCF_01198 6.2e-168 IQ Enoyl-(Acyl carrier protein) reductase
LOHBLHCF_01199 3.9e-41 yhjA S Excalibur calcium-binding domain
LOHBLHCF_01200 1.4e-262 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOHBLHCF_01201 6.9e-27 yhjC S Protein of unknown function (DUF3311)
LOHBLHCF_01202 6.7e-60 yhjD
LOHBLHCF_01203 9.1e-110 yhjE S SNARE associated Golgi protein
LOHBLHCF_01204 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
LOHBLHCF_01205 1.1e-278 yhjG CH FAD binding domain
LOHBLHCF_01206 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
LOHBLHCF_01207 3.4e-214 glcP G Major Facilitator Superfamily
LOHBLHCF_01208 2.5e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
LOHBLHCF_01209 4.9e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
LOHBLHCF_01210 5.4e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
LOHBLHCF_01211 6.5e-187 yhjM 5.1.1.1 K Transcriptional regulator
LOHBLHCF_01212 4.2e-201 abrB S membrane
LOHBLHCF_01213 7.4e-209 EGP Transmembrane secretion effector
LOHBLHCF_01214 0.0 S Sugar transport-related sRNA regulator N-term
LOHBLHCF_01215 2.2e-78 yhjR S Rubrerythrin
LOHBLHCF_01216 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
LOHBLHCF_01217 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LOHBLHCF_01218 2.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LOHBLHCF_01219 0.0 sbcC L COG0419 ATPase involved in DNA repair
LOHBLHCF_01220 2.1e-48 yisB V COG1403 Restriction endonuclease
LOHBLHCF_01221 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
LOHBLHCF_01222 5.3e-63 gerPE S Spore germination protein GerPE
LOHBLHCF_01223 3.1e-23 gerPD S Spore germination protein
LOHBLHCF_01224 5.3e-54 gerPC S Spore germination protein
LOHBLHCF_01225 4e-34 gerPB S cell differentiation
LOHBLHCF_01226 1.9e-33 gerPA S Spore germination protein
LOHBLHCF_01227 1.5e-22 yisI S Spo0E like sporulation regulatory protein
LOHBLHCF_01228 2e-174 cotH M Spore Coat
LOHBLHCF_01229 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LOHBLHCF_01230 3e-57 yisL S UPF0344 protein
LOHBLHCF_01231 0.0 wprA O Belongs to the peptidase S8 family
LOHBLHCF_01232 1.5e-100 yisN S Protein of unknown function (DUF2777)
LOHBLHCF_01233 0.0 asnO 6.3.5.4 E Asparagine synthase
LOHBLHCF_01234 4.7e-88 yizA S Damage-inducible protein DinB
LOHBLHCF_01235 1e-145 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
LOHBLHCF_01236 1.5e-242 yisQ V Mate efflux family protein
LOHBLHCF_01237 4.5e-160 yisR K Transcriptional regulator
LOHBLHCF_01238 6.9e-184 purR K helix_turn _helix lactose operon repressor
LOHBLHCF_01239 1.6e-191 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
LOHBLHCF_01240 1.8e-92 yisT S DinB family
LOHBLHCF_01241 7.8e-106 argO S Lysine exporter protein LysE YggA
LOHBLHCF_01242 2.2e-276 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOHBLHCF_01243 2e-35 mcbG S Pentapeptide repeats (9 copies)
LOHBLHCF_01244 1.2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LOHBLHCF_01245 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
LOHBLHCF_01246 9.3e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LOHBLHCF_01247 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LOHBLHCF_01248 7.6e-118 comB 3.1.3.71 H Belongs to the ComB family
LOHBLHCF_01249 1.6e-140 yitD 4.4.1.19 S synthase
LOHBLHCF_01250 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOHBLHCF_01251 4.6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LOHBLHCF_01252 2e-228 yitG EGP Major facilitator Superfamily
LOHBLHCF_01253 1.8e-153 yitH K Acetyltransferase (GNAT) domain
LOHBLHCF_01254 1e-70 yjcF S Acetyltransferase (GNAT) domain
LOHBLHCF_01255 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LOHBLHCF_01256 5.6e-54 yajQ S Belongs to the UPF0234 family
LOHBLHCF_01257 6.9e-161 cvfB S protein conserved in bacteria
LOHBLHCF_01258 3.2e-93
LOHBLHCF_01259 2.8e-171
LOHBLHCF_01260 1.5e-97 S Sporulation delaying protein SdpA
LOHBLHCF_01261 4.5e-58 K Transcriptional regulator PadR-like family
LOHBLHCF_01262 4.7e-92
LOHBLHCF_01263 1.4e-44 yitR S Domain of unknown function (DUF3784)
LOHBLHCF_01264 1e-306 nprB 3.4.24.28 E Peptidase M4
LOHBLHCF_01265 1.2e-157 yitS S protein conserved in bacteria
LOHBLHCF_01266 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
LOHBLHCF_01267 5e-73 ipi S Intracellular proteinase inhibitor
LOHBLHCF_01268 1.2e-17 S Protein of unknown function (DUF3813)
LOHBLHCF_01270 2.1e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LOHBLHCF_01271 1.7e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LOHBLHCF_01272 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
LOHBLHCF_01273 1.5e-22 pilT S Proteolipid membrane potential modulator
LOHBLHCF_01274 7.5e-269 yitY C D-arabinono-1,4-lactone oxidase
LOHBLHCF_01275 5.8e-53 norB G Major Facilitator Superfamily
LOHBLHCF_01276 1e-28 norB G Major Facilitator Superfamily
LOHBLHCF_01277 1.9e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LOHBLHCF_01278 1.7e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LOHBLHCF_01279 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LOHBLHCF_01280 3.2e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LOHBLHCF_01281 1.7e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LOHBLHCF_01282 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
LOHBLHCF_01283 4.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LOHBLHCF_01284 9.5e-28 yjzC S YjzC-like protein
LOHBLHCF_01285 2.3e-16 yjzD S Protein of unknown function (DUF2929)
LOHBLHCF_01286 6.2e-142 yjaU I carboxylic ester hydrolase activity
LOHBLHCF_01287 2e-100 yjaV
LOHBLHCF_01288 2.5e-183 med S Transcriptional activator protein med
LOHBLHCF_01289 7.3e-26 comZ S ComZ
LOHBLHCF_01290 2.7e-22 yjzB
LOHBLHCF_01291 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOHBLHCF_01292 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LOHBLHCF_01293 3.3e-149 yjaZ O Zn-dependent protease
LOHBLHCF_01294 1.8e-184 appD P Belongs to the ABC transporter superfamily
LOHBLHCF_01295 2.7e-185 appF E Belongs to the ABC transporter superfamily
LOHBLHCF_01296 1.4e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
LOHBLHCF_01297 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOHBLHCF_01298 1.8e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOHBLHCF_01299 1.9e-146 yjbA S Belongs to the UPF0736 family
LOHBLHCF_01300 6.8e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LOHBLHCF_01301 9.4e-308 oppA E ABC transporter substrate-binding protein
LOHBLHCF_01302 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOHBLHCF_01303 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOHBLHCF_01304 7.5e-197 oppD P Belongs to the ABC transporter superfamily
LOHBLHCF_01305 1.2e-171 oppF E Belongs to the ABC transporter superfamily
LOHBLHCF_01306 2.7e-203 yjbB EGP Major Facilitator Superfamily
LOHBLHCF_01307 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOHBLHCF_01308 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LOHBLHCF_01309 1.3e-111 yjbE P Integral membrane protein TerC family
LOHBLHCF_01310 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LOHBLHCF_01311 3.4e-219 yjbF S Competence protein
LOHBLHCF_01312 0.0 pepF E oligoendopeptidase F
LOHBLHCF_01313 1.8e-20
LOHBLHCF_01314 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LOHBLHCF_01315 3.7e-72 yjbI S Bacterial-like globin
LOHBLHCF_01316 1.3e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LOHBLHCF_01317 7.1e-101 yjbK S protein conserved in bacteria
LOHBLHCF_01318 2.1e-61 yjbL S Belongs to the UPF0738 family
LOHBLHCF_01319 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
LOHBLHCF_01320 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LOHBLHCF_01321 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LOHBLHCF_01322 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LOHBLHCF_01323 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LOHBLHCF_01324 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LOHBLHCF_01325 4.9e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
LOHBLHCF_01326 8.8e-217 thiO 1.4.3.19 E Glycine oxidase
LOHBLHCF_01327 2.6e-29 thiS H thiamine diphosphate biosynthetic process
LOHBLHCF_01328 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LOHBLHCF_01329 1.5e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LOHBLHCF_01330 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LOHBLHCF_01331 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LOHBLHCF_01332 5.9e-54 yjbX S Spore coat protein
LOHBLHCF_01333 5.2e-83 cotZ S Spore coat protein
LOHBLHCF_01334 3.4e-96 cotY S Spore coat protein Z
LOHBLHCF_01335 1.4e-38 cotX S Spore Coat Protein X and V domain
LOHBLHCF_01336 1.4e-10 cotW
LOHBLHCF_01337 1.4e-23 cotV S Spore Coat Protein X and V domain
LOHBLHCF_01338 1.9e-56 yjcA S Protein of unknown function (DUF1360)
LOHBLHCF_01341 4.9e-38 spoVIF S Stage VI sporulation protein F
LOHBLHCF_01342 0.0 yjcD 3.6.4.12 L DNA helicase
LOHBLHCF_01343 1.7e-38
LOHBLHCF_01344 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOHBLHCF_01345 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LOHBLHCF_01346 2.9e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
LOHBLHCF_01347 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LOHBLHCF_01348 8.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LOHBLHCF_01349 1e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
LOHBLHCF_01350 6e-211 yjcL S Protein of unknown function (DUF819)
LOHBLHCF_01352 5.2e-18
LOHBLHCF_01353 4.6e-38
LOHBLHCF_01354 1e-29
LOHBLHCF_01355 1.5e-237 M nucleic acid phosphodiester bond hydrolysis
LOHBLHCF_01356 4.3e-70
LOHBLHCF_01357 7.3e-16
LOHBLHCF_01358 1.5e-49
LOHBLHCF_01359 3.7e-21 S YolD-like protein
LOHBLHCF_01362 2.4e-33 yjcS S Antibiotic biosynthesis monooxygenase
LOHBLHCF_01364 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
LOHBLHCF_01365 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
LOHBLHCF_01366 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
LOHBLHCF_01367 4.1e-50 yjdF S Protein of unknown function (DUF2992)
LOHBLHCF_01368 2.2e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
LOHBLHCF_01370 1.2e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LOHBLHCF_01371 1.6e-28 S Domain of unknown function (DUF4177)
LOHBLHCF_01372 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
LOHBLHCF_01373 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LOHBLHCF_01375 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
LOHBLHCF_01376 5.5e-83 S Protein of unknown function (DUF2690)
LOHBLHCF_01377 3.6e-21 yjfB S Putative motility protein
LOHBLHCF_01378 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
LOHBLHCF_01379 1.2e-45 T PhoQ Sensor
LOHBLHCF_01380 8.9e-104 yjgB S Domain of unknown function (DUF4309)
LOHBLHCF_01381 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LOHBLHCF_01382 4.3e-95 yjgD S Protein of unknown function (DUF1641)
LOHBLHCF_01383 8.7e-07 S Domain of unknown function (DUF4352)
LOHBLHCF_01384 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
LOHBLHCF_01386 1.9e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
LOHBLHCF_01387 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LOHBLHCF_01388 1.4e-29
LOHBLHCF_01389 6.6e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LOHBLHCF_01390 1.9e-122 ybbM S transport system, permease component
LOHBLHCF_01391 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
LOHBLHCF_01392 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
LOHBLHCF_01393 1.3e-90 yjlB S Cupin domain
LOHBLHCF_01394 7.1e-66 yjlC S Protein of unknown function (DUF1641)
LOHBLHCF_01395 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
LOHBLHCF_01396 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
LOHBLHCF_01397 2.1e-247 yjmB G symporter YjmB
LOHBLHCF_01398 4.9e-190 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
LOHBLHCF_01399 2.8e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
LOHBLHCF_01400 2.2e-134 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LOHBLHCF_01401 9.4e-61 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LOHBLHCF_01402 1.3e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_01403 3.5e-225 exuT G Sugar (and other) transporter
LOHBLHCF_01404 1.2e-183 exuR K transcriptional
LOHBLHCF_01405 1.5e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
LOHBLHCF_01406 8.1e-282 uxaA 4.2.1.7, 4.4.1.24 G Altronate
LOHBLHCF_01407 7.4e-130 MA20_18170 S membrane transporter protein
LOHBLHCF_01408 2.3e-78 yjoA S DinB family
LOHBLHCF_01409 2.1e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
LOHBLHCF_01410 1.5e-211 S response regulator aspartate phosphatase
LOHBLHCF_01412 6.3e-41 S YCII-related domain
LOHBLHCF_01413 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
LOHBLHCF_01414 6.1e-61 yjqA S Bacterial PH domain
LOHBLHCF_01415 3.3e-109 yjqB S Pfam:DUF867
LOHBLHCF_01416 4.4e-160 ydbD P Catalase
LOHBLHCF_01417 1.6e-111 xkdA E IrrE N-terminal-like domain
LOHBLHCF_01418 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
LOHBLHCF_01420 1.7e-156 xkdB K sequence-specific DNA binding
LOHBLHCF_01421 4.1e-118 xkdC L Bacterial dnaA protein
LOHBLHCF_01424 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
LOHBLHCF_01425 2.4e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LOHBLHCF_01426 1.2e-138 xtmA L phage terminase small subunit
LOHBLHCF_01427 1.2e-252 xtmB S phage terminase, large subunit
LOHBLHCF_01428 1.6e-285 yqbA S portal protein
LOHBLHCF_01429 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
LOHBLHCF_01430 5.8e-169 xkdG S Phage capsid family
LOHBLHCF_01431 5.1e-63 yqbG S Protein of unknown function (DUF3199)
LOHBLHCF_01432 3.3e-64 yqbH S Domain of unknown function (DUF3599)
LOHBLHCF_01433 9.9e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
LOHBLHCF_01434 1.9e-77 xkdJ
LOHBLHCF_01435 9.3e-256 xkdK S Phage tail sheath C-terminal domain
LOHBLHCF_01436 6.1e-76 xkdM S Phage tail tube protein
LOHBLHCF_01437 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
LOHBLHCF_01438 0.0 xkdO L Transglycosylase SLT domain
LOHBLHCF_01439 1.7e-120 xkdP S Lysin motif
LOHBLHCF_01440 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
LOHBLHCF_01441 3e-38 xkdR S Protein of unknown function (DUF2577)
LOHBLHCF_01442 3.1e-69 xkdS S Protein of unknown function (DUF2634)
LOHBLHCF_01443 7.4e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LOHBLHCF_01444 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LOHBLHCF_01445 6.7e-41
LOHBLHCF_01446 1.4e-100
LOHBLHCF_01448 4.9e-14 xkdX
LOHBLHCF_01449 3.9e-28 xhlA S Haemolysin XhlA
LOHBLHCF_01450 9.3e-40 xhlB S SPP1 phage holin
LOHBLHCF_01451 4.2e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOHBLHCF_01453 6.7e-23 spoIISB S Stage II sporulation protein SB
LOHBLHCF_01454 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
LOHBLHCF_01455 5.8e-175 pit P phosphate transporter
LOHBLHCF_01456 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
LOHBLHCF_01457 4.8e-238 steT E amino acid
LOHBLHCF_01458 6.7e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LOHBLHCF_01459 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LOHBLHCF_01460 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOHBLHCF_01462 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOHBLHCF_01463 2.4e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
LOHBLHCF_01464 5.1e-153 dppA E D-aminopeptidase
LOHBLHCF_01465 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOHBLHCF_01466 4.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOHBLHCF_01467 1.3e-187 dppD P Belongs to the ABC transporter superfamily
LOHBLHCF_01468 0.0 dppE E ABC transporter substrate-binding protein
LOHBLHCF_01470 4.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LOHBLHCF_01471 4.4e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LOHBLHCF_01472 3.1e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LOHBLHCF_01473 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
LOHBLHCF_01474 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
LOHBLHCF_01475 1.2e-160 ykgA E Amidinotransferase
LOHBLHCF_01476 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
LOHBLHCF_01477 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LOHBLHCF_01478 5.5e-09
LOHBLHCF_01479 2.3e-128 ykjA S Protein of unknown function (DUF421)
LOHBLHCF_01480 4.8e-96 ykkA S Protein of unknown function (DUF664)
LOHBLHCF_01481 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LOHBLHCF_01482 3.5e-55 ykkC P Multidrug resistance protein
LOHBLHCF_01483 7e-50 ykkD P Multidrug resistance protein
LOHBLHCF_01484 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LOHBLHCF_01485 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LOHBLHCF_01486 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LOHBLHCF_01487 1.3e-70 ohrA O Organic hydroperoxide resistance protein
LOHBLHCF_01488 4.8e-73 ohrR K COG1846 Transcriptional regulators
LOHBLHCF_01489 2.4e-71 ohrB O Organic hydroperoxide resistance protein
LOHBLHCF_01490 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
LOHBLHCF_01491 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LOHBLHCF_01492 5e-176 isp O Belongs to the peptidase S8 family
LOHBLHCF_01493 3.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LOHBLHCF_01494 5.3e-136 ykoC P Cobalt transport protein
LOHBLHCF_01495 1.6e-302 P ABC transporter, ATP-binding protein
LOHBLHCF_01496 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
LOHBLHCF_01497 5.1e-110 ykoF S YKOF-related Family
LOHBLHCF_01498 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_01499 2e-242 ykoH 2.7.13.3 T Histidine kinase
LOHBLHCF_01500 1.2e-112 ykoI S Peptidase propeptide and YPEB domain
LOHBLHCF_01501 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
LOHBLHCF_01504 2.2e-222 mgtE P Acts as a magnesium transporter
LOHBLHCF_01505 1.4e-53 tnrA K transcriptional
LOHBLHCF_01506 5.9e-18
LOHBLHCF_01507 6.9e-26 ykoL
LOHBLHCF_01508 1.3e-81 mhqR K transcriptional
LOHBLHCF_01509 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LOHBLHCF_01510 2.7e-97 ykoP G polysaccharide deacetylase
LOHBLHCF_01511 8.6e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
LOHBLHCF_01512 0.0 ykoS
LOHBLHCF_01513 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOHBLHCF_01514 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
LOHBLHCF_01515 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LOHBLHCF_01516 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
LOHBLHCF_01517 2.7e-109 ykoX S membrane-associated protein
LOHBLHCF_01518 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LOHBLHCF_01519 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOHBLHCF_01520 7.7e-107 rsgI S Anti-sigma factor N-terminus
LOHBLHCF_01521 1.9e-26 sspD S small acid-soluble spore protein
LOHBLHCF_01522 3.3e-124 ykrK S Domain of unknown function (DUF1836)
LOHBLHCF_01523 3.5e-155 htpX O Belongs to the peptidase M48B family
LOHBLHCF_01524 1.8e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
LOHBLHCF_01525 1.2e-10 ydfR S Protein of unknown function (DUF421)
LOHBLHCF_01526 4.1e-18 ykzE
LOHBLHCF_01527 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
LOHBLHCF_01528 0.0 kinE 2.7.13.3 T Histidine kinase
LOHBLHCF_01529 1.6e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LOHBLHCF_01531 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LOHBLHCF_01532 8.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LOHBLHCF_01533 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LOHBLHCF_01534 2.9e-229 mtnE 2.6.1.83 E Aminotransferase
LOHBLHCF_01535 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LOHBLHCF_01536 2.1e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LOHBLHCF_01537 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LOHBLHCF_01538 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LOHBLHCF_01539 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
LOHBLHCF_01540 6.4e-09 S Spo0E like sporulation regulatory protein
LOHBLHCF_01541 1.5e-63 eag
LOHBLHCF_01542 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
LOHBLHCF_01543 1.3e-75 ykvE K transcriptional
LOHBLHCF_01544 3.3e-125 motB N Flagellar motor protein
LOHBLHCF_01545 2.7e-138 motA N flagellar motor
LOHBLHCF_01546 0.0 clpE O Belongs to the ClpA ClpB family
LOHBLHCF_01547 1.1e-64 ykvI S membrane
LOHBLHCF_01548 1.8e-102 ykvI S membrane
LOHBLHCF_01549 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LOHBLHCF_01550 1.4e-80 queD 4.1.2.50, 4.2.3.12 H synthase
LOHBLHCF_01551 1.7e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LOHBLHCF_01552 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LOHBLHCF_01553 2.9e-60 ykvN K Transcriptional regulator
LOHBLHCF_01554 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
LOHBLHCF_01555 5.6e-46 ykvR S Protein of unknown function (DUF3219)
LOHBLHCF_01556 6e-25 ykvS S protein conserved in bacteria
LOHBLHCF_01557 2.7e-28
LOHBLHCF_01558 7e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
LOHBLHCF_01559 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOHBLHCF_01560 4.9e-90 stoA CO thiol-disulfide
LOHBLHCF_01561 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LOHBLHCF_01562 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LOHBLHCF_01564 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
LOHBLHCF_01566 7.6e-128 glcT K antiterminator
LOHBLHCF_01567 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOHBLHCF_01568 2.1e-39 ptsH G phosphocarrier protein HPr
LOHBLHCF_01569 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LOHBLHCF_01570 2.1e-38 splA S Transcriptional regulator
LOHBLHCF_01571 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
LOHBLHCF_01572 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOHBLHCF_01573 2.8e-258 mcpC NT chemotaxis protein
LOHBLHCF_01574 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LOHBLHCF_01575 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
LOHBLHCF_01576 2.7e-119 ykwD J protein with SCP PR1 domains
LOHBLHCF_01577 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
LOHBLHCF_01578 0.0 pilS 2.7.13.3 T Histidine kinase
LOHBLHCF_01579 2.6e-222 patA 2.6.1.1 E Aminotransferase
LOHBLHCF_01580 1.3e-15
LOHBLHCF_01581 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
LOHBLHCF_01582 1.7e-84 ykyB S YkyB-like protein
LOHBLHCF_01583 2.8e-238 ykuC EGP Major facilitator Superfamily
LOHBLHCF_01584 8.7e-87 ykuD S protein conserved in bacteria
LOHBLHCF_01585 1.4e-164 ykuE S Metallophosphoesterase
LOHBLHCF_01586 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_01587 1.1e-233 ykuI T Diguanylate phosphodiesterase
LOHBLHCF_01588 3.9e-37 ykuJ S protein conserved in bacteria
LOHBLHCF_01589 2.2e-93 ykuK S Ribonuclease H-like
LOHBLHCF_01590 3.9e-27 ykzF S Antirepressor AbbA
LOHBLHCF_01591 1.6e-76 ykuL S CBS domain
LOHBLHCF_01592 3.5e-168 ccpC K Transcriptional regulator
LOHBLHCF_01593 1.7e-84 fld C Flavodoxin domain
LOHBLHCF_01594 6.7e-175 ykuO
LOHBLHCF_01595 3.9e-78 fld C Flavodoxin
LOHBLHCF_01596 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LOHBLHCF_01597 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LOHBLHCF_01598 9e-37 ykuS S Belongs to the UPF0180 family
LOHBLHCF_01599 8.3e-201 L COG3666 Transposase and inactivated derivatives
LOHBLHCF_01600 8.8e-142 ykuT M Mechanosensitive ion channel
LOHBLHCF_01601 3.9e-101 ykuU O Alkyl hydroperoxide reductase
LOHBLHCF_01602 4.1e-80 ykuV CO thiol-disulfide
LOHBLHCF_01603 4.2e-93 rok K Repressor of ComK
LOHBLHCF_01604 1e-144 yknT
LOHBLHCF_01605 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LOHBLHCF_01606 2e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LOHBLHCF_01607 2.4e-245 moeA 2.10.1.1 H molybdopterin
LOHBLHCF_01608 4.9e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LOHBLHCF_01609 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
LOHBLHCF_01610 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LOHBLHCF_01611 2e-121 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOHBLHCF_01612 2.9e-179 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOHBLHCF_01613 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOHBLHCF_01614 5.2e-114 yknW S Yip1 domain
LOHBLHCF_01615 9.5e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LOHBLHCF_01616 2.5e-124 macB V ABC transporter, ATP-binding protein
LOHBLHCF_01617 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
LOHBLHCF_01618 1.2e-135 fruR K Transcriptional regulator
LOHBLHCF_01619 4e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LOHBLHCF_01620 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LOHBLHCF_01622 8.3e-201 L COG3666 Transposase and inactivated derivatives
LOHBLHCF_01623 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LOHBLHCF_01624 8.1e-39 ykoA
LOHBLHCF_01625 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LOHBLHCF_01626 3.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LOHBLHCF_01627 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LOHBLHCF_01628 9.4e-12 S Uncharacterized protein YkpC
LOHBLHCF_01629 7.7e-183 mreB D Rod-share determining protein MreBH
LOHBLHCF_01630 1.5e-43 abrB K of stationary sporulation gene expression
LOHBLHCF_01631 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
LOHBLHCF_01632 2.1e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
LOHBLHCF_01633 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
LOHBLHCF_01634 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LOHBLHCF_01635 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOHBLHCF_01636 8.2e-31 ykzG S Belongs to the UPF0356 family
LOHBLHCF_01637 1.2e-146 ykrA S hydrolases of the HAD superfamily
LOHBLHCF_01638 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LOHBLHCF_01640 1.1e-107 recN L Putative cell-wall binding lipoprotein
LOHBLHCF_01641 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LOHBLHCF_01642 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LOHBLHCF_01643 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LOHBLHCF_01644 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LOHBLHCF_01645 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
LOHBLHCF_01646 1e-276 speA 4.1.1.19 E Arginine
LOHBLHCF_01647 1.7e-41 yktA S Belongs to the UPF0223 family
LOHBLHCF_01648 4.6e-117 yktB S Belongs to the UPF0637 family
LOHBLHCF_01649 7.2e-26 ykzI
LOHBLHCF_01650 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
LOHBLHCF_01651 3.8e-76 ykzC S Acetyltransferase (GNAT) family
LOHBLHCF_01652 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LOHBLHCF_01653 4.7e-260 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
LOHBLHCF_01654 0.0 ylaA
LOHBLHCF_01655 2.7e-42 ylaB
LOHBLHCF_01656 1.3e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_01657 3.5e-11 sigC S Putative zinc-finger
LOHBLHCF_01658 1.8e-38 ylaE
LOHBLHCF_01659 8.2e-22 S Family of unknown function (DUF5325)
LOHBLHCF_01660 0.0 typA T GTP-binding protein TypA
LOHBLHCF_01661 5.6e-47 ylaH S YlaH-like protein
LOHBLHCF_01662 2.5e-32 ylaI S protein conserved in bacteria
LOHBLHCF_01663 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LOHBLHCF_01664 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
LOHBLHCF_01665 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LOHBLHCF_01666 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
LOHBLHCF_01667 8.7e-44 ylaN S Belongs to the UPF0358 family
LOHBLHCF_01668 2.5e-212 ftsW D Belongs to the SEDS family
LOHBLHCF_01669 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LOHBLHCF_01670 3.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LOHBLHCF_01671 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LOHBLHCF_01672 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LOHBLHCF_01673 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LOHBLHCF_01674 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LOHBLHCF_01675 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LOHBLHCF_01676 1.5e-166 ctaG S cytochrome c oxidase
LOHBLHCF_01677 7e-62 ylbA S YugN-like family
LOHBLHCF_01678 2.6e-74 ylbB T COG0517 FOG CBS domain
LOHBLHCF_01679 2.8e-199 ylbC S protein with SCP PR1 domains
LOHBLHCF_01680 2.6e-62 ylbD S Putative coat protein
LOHBLHCF_01681 6.7e-37 ylbE S YlbE-like protein
LOHBLHCF_01682 1.8e-75 ylbF S Belongs to the UPF0342 family
LOHBLHCF_01683 7.5e-39 ylbG S UPF0298 protein
LOHBLHCF_01684 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
LOHBLHCF_01685 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LOHBLHCF_01686 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
LOHBLHCF_01687 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
LOHBLHCF_01688 6.8e-187 ylbL T Belongs to the peptidase S16 family
LOHBLHCF_01689 3e-229 ylbM S Belongs to the UPF0348 family
LOHBLHCF_01691 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
LOHBLHCF_01692 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LOHBLHCF_01693 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LOHBLHCF_01694 1.5e-88 ylbP K n-acetyltransferase
LOHBLHCF_01695 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LOHBLHCF_01696 6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LOHBLHCF_01697 2.9e-78 mraZ K Belongs to the MraZ family
LOHBLHCF_01698 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LOHBLHCF_01699 3.7e-44 ftsL D Essential cell division protein
LOHBLHCF_01700 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LOHBLHCF_01701 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
LOHBLHCF_01702 8.9e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LOHBLHCF_01703 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LOHBLHCF_01704 2.2e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LOHBLHCF_01705 5.7e-186 spoVE D Belongs to the SEDS family
LOHBLHCF_01706 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LOHBLHCF_01707 9e-167 murB 1.3.1.98 M cell wall formation
LOHBLHCF_01708 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LOHBLHCF_01709 2.4e-103 ylxW S protein conserved in bacteria
LOHBLHCF_01710 3e-102 ylxX S protein conserved in bacteria
LOHBLHCF_01711 6.2e-58 sbp S small basic protein
LOHBLHCF_01712 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LOHBLHCF_01713 4.4e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LOHBLHCF_01714 0.0 bpr O COG1404 Subtilisin-like serine proteases
LOHBLHCF_01716 8.9e-170 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LOHBLHCF_01717 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOHBLHCF_01718 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOHBLHCF_01719 5.3e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LOHBLHCF_01720 2.2e-251 argE 3.5.1.16 E Acetylornithine deacetylase
LOHBLHCF_01721 2.4e-37 ylmC S sporulation protein
LOHBLHCF_01722 3.5e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LOHBLHCF_01723 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LOHBLHCF_01724 6.7e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LOHBLHCF_01725 1.3e-39 yggT S membrane
LOHBLHCF_01726 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LOHBLHCF_01727 2.6e-67 divIVA D Cell division initiation protein
LOHBLHCF_01728 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LOHBLHCF_01729 3.8e-63 dksA T COG1734 DnaK suppressor protein
LOHBLHCF_01730 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LOHBLHCF_01731 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LOHBLHCF_01732 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LOHBLHCF_01733 9e-232 pyrP F Xanthine uracil
LOHBLHCF_01734 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LOHBLHCF_01735 3.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LOHBLHCF_01736 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LOHBLHCF_01737 0.0 carB 6.3.5.5 F Belongs to the CarB family
LOHBLHCF_01738 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LOHBLHCF_01739 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LOHBLHCF_01740 1.4e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LOHBLHCF_01741 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LOHBLHCF_01743 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LOHBLHCF_01744 1.8e-179 cysP P phosphate transporter
LOHBLHCF_01745 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LOHBLHCF_01746 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
LOHBLHCF_01747 2e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LOHBLHCF_01748 1.3e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
LOHBLHCF_01749 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
LOHBLHCF_01750 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LOHBLHCF_01751 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
LOHBLHCF_01752 2.4e-156 yloC S stress-induced protein
LOHBLHCF_01753 1.5e-40 ylzA S Belongs to the UPF0296 family
LOHBLHCF_01754 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LOHBLHCF_01755 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LOHBLHCF_01756 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LOHBLHCF_01757 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOHBLHCF_01758 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LOHBLHCF_01759 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LOHBLHCF_01760 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LOHBLHCF_01761 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LOHBLHCF_01762 1.6e-140 stp 3.1.3.16 T phosphatase
LOHBLHCF_01763 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LOHBLHCF_01764 2.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LOHBLHCF_01765 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LOHBLHCF_01766 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
LOHBLHCF_01767 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LOHBLHCF_01768 5.5e-59 asp S protein conserved in bacteria
LOHBLHCF_01769 1.1e-300 yloV S kinase related to dihydroxyacetone kinase
LOHBLHCF_01770 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
LOHBLHCF_01771 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
LOHBLHCF_01772 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LOHBLHCF_01773 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LOHBLHCF_01774 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LOHBLHCF_01775 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LOHBLHCF_01776 5.1e-128 IQ reductase
LOHBLHCF_01777 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOHBLHCF_01778 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LOHBLHCF_01779 0.0 smc D Required for chromosome condensation and partitioning
LOHBLHCF_01780 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LOHBLHCF_01781 2.9e-87
LOHBLHCF_01782 2.1e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LOHBLHCF_01783 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LOHBLHCF_01784 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LOHBLHCF_01785 4.5e-36 ylqC S Belongs to the UPF0109 family
LOHBLHCF_01786 1.4e-60 ylqD S YlqD protein
LOHBLHCF_01787 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LOHBLHCF_01788 2.7e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LOHBLHCF_01789 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LOHBLHCF_01790 3.5e-156 2.1.1.72 L Adenine specific DNA methylase Mod
LOHBLHCF_01791 0.0 res 3.1.21.5 L Type III restriction enzyme, res subunit
LOHBLHCF_01792 6.1e-30
LOHBLHCF_01793 9.5e-07
LOHBLHCF_01795 2.3e-87 D ftsk spoiiie
LOHBLHCF_01796 1.1e-69
LOHBLHCF_01797 4.4e-31
LOHBLHCF_01798 3e-112 L DNA integration
LOHBLHCF_01799 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LOHBLHCF_01800 2.2e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LOHBLHCF_01801 1.8e-288 ylqG
LOHBLHCF_01802 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
LOHBLHCF_01803 7.6e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LOHBLHCF_01804 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LOHBLHCF_01805 1.2e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LOHBLHCF_01806 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOHBLHCF_01807 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LOHBLHCF_01808 2.5e-169 xerC L tyrosine recombinase XerC
LOHBLHCF_01809 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LOHBLHCF_01810 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LOHBLHCF_01811 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LOHBLHCF_01812 8.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LOHBLHCF_01813 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
LOHBLHCF_01814 1.9e-31 fliE N Flagellar hook-basal body
LOHBLHCF_01815 7e-255 fliF N The M ring may be actively involved in energy transduction
LOHBLHCF_01816 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LOHBLHCF_01817 8.2e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
LOHBLHCF_01818 1e-240 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LOHBLHCF_01819 1.5e-69 fliJ N Flagellar biosynthesis chaperone
LOHBLHCF_01820 5.7e-35 ylxF S MgtE intracellular N domain
LOHBLHCF_01821 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
LOHBLHCF_01822 6e-96 fliZ N Flagellar biosynthesis protein, FliO
LOHBLHCF_01823 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
LOHBLHCF_01824 2.2e-36 fliQ N Role in flagellar biosynthesis
LOHBLHCF_01825 4e-131 fliR N Flagellar biosynthetic protein FliR
LOHBLHCF_01826 3.1e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LOHBLHCF_01827 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LOHBLHCF_01828 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
LOHBLHCF_01829 2.8e-157 flhG D Belongs to the ParA family
LOHBLHCF_01830 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LOHBLHCF_01831 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
LOHBLHCF_01832 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
LOHBLHCF_01833 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LOHBLHCF_01834 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LOHBLHCF_01835 7.4e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOHBLHCF_01836 3.1e-76 ylxL
LOHBLHCF_01837 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
LOHBLHCF_01838 1.4e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LOHBLHCF_01839 1e-125 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LOHBLHCF_01840 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LOHBLHCF_01841 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LOHBLHCF_01842 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
LOHBLHCF_01843 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LOHBLHCF_01844 1.5e-225 rasP M zinc metalloprotease
LOHBLHCF_01845 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LOHBLHCF_01846 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOHBLHCF_01848 1.4e-137 spaB S Lantibiotic dehydratase, C terminus
LOHBLHCF_01849 6.9e-102 spaT V ABC transporter
LOHBLHCF_01850 1.3e-51 spaC2 V PFAM Lanthionine synthetase
LOHBLHCF_01851 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
LOHBLHCF_01852 1.1e-203 nusA K Participates in both transcription termination and antitermination
LOHBLHCF_01853 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
LOHBLHCF_01854 3.1e-47 ylxQ J ribosomal protein
LOHBLHCF_01855 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LOHBLHCF_01856 3.9e-44 ylxP S protein conserved in bacteria
LOHBLHCF_01857 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LOHBLHCF_01858 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LOHBLHCF_01859 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LOHBLHCF_01860 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LOHBLHCF_01861 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LOHBLHCF_01862 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
LOHBLHCF_01863 4.4e-233 pepR S Belongs to the peptidase M16 family
LOHBLHCF_01864 2.6e-42 ymxH S YlmC YmxH family
LOHBLHCF_01865 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
LOHBLHCF_01866 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LOHBLHCF_01867 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LOHBLHCF_01868 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LOHBLHCF_01869 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LOHBLHCF_01870 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOHBLHCF_01871 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
LOHBLHCF_01872 4.4e-32 S YlzJ-like protein
LOHBLHCF_01873 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LOHBLHCF_01874 1.4e-133 ymfC K Transcriptional regulator
LOHBLHCF_01875 3.8e-205 ymfD EGP Major facilitator Superfamily
LOHBLHCF_01876 7.8e-233 ymfF S Peptidase M16
LOHBLHCF_01877 1.4e-242 ymfH S zinc protease
LOHBLHCF_01878 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LOHBLHCF_01879 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
LOHBLHCF_01880 2.7e-143 ymfK S Protein of unknown function (DUF3388)
LOHBLHCF_01881 1.9e-124 ymfM S protein conserved in bacteria
LOHBLHCF_01882 1.6e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LOHBLHCF_01883 4.3e-236 cinA 3.5.1.42 S Belongs to the CinA family
LOHBLHCF_01884 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LOHBLHCF_01885 1.7e-213 pbpX V Beta-lactamase
LOHBLHCF_01886 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
LOHBLHCF_01887 1.9e-152 ymdB S protein conserved in bacteria
LOHBLHCF_01888 1.2e-36 spoVS S Stage V sporulation protein S
LOHBLHCF_01889 3.6e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LOHBLHCF_01890 1.8e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LOHBLHCF_01891 1.3e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LOHBLHCF_01892 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LOHBLHCF_01893 2.2e-88 cotE S Spore coat protein
LOHBLHCF_01894 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LOHBLHCF_01895 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LOHBLHCF_01896 1.3e-68 S Regulatory protein YrvL
LOHBLHCF_01897 1.1e-95 ymcC S Membrane
LOHBLHCF_01898 1.8e-102 pksA K Transcriptional regulator
LOHBLHCF_01899 4.4e-61 ymzB
LOHBLHCF_01900 2.3e-161 ymaE S Metallo-beta-lactamase superfamily
LOHBLHCF_01901 8.6e-251 aprX O Belongs to the peptidase S8 family
LOHBLHCF_01902 1.9e-07 K Transcriptional regulator
LOHBLHCF_01903 2.1e-126 ymaC S Replication protein
LOHBLHCF_01904 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
LOHBLHCF_01905 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
LOHBLHCF_01906 5.4e-50 ebrA P Small Multidrug Resistance protein
LOHBLHCF_01908 2.1e-46 ymaF S YmaF family
LOHBLHCF_01909 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LOHBLHCF_01910 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LOHBLHCF_01911 8.2e-23
LOHBLHCF_01912 4.5e-22 ymzA
LOHBLHCF_01913 1.6e-48 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LOHBLHCF_01914 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOHBLHCF_01915 5.9e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOHBLHCF_01916 7.6e-109 ymaB
LOHBLHCF_01917 1.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOHBLHCF_01918 6.6e-176 spoVK O stage V sporulation protein K
LOHBLHCF_01919 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LOHBLHCF_01920 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LOHBLHCF_01921 4.3e-68 glnR K transcriptional
LOHBLHCF_01922 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
LOHBLHCF_01923 1.3e-38 L Arm DNA-binding domain
LOHBLHCF_01924 1.2e-82 dnaB 3.6.4.12 L replicative DNA helicase
LOHBLHCF_01925 6.4e-14
LOHBLHCF_01927 7.1e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
LOHBLHCF_01928 3.2e-27 S PFAM FRG domain
LOHBLHCF_01929 1.2e-48 V HNH endonuclease
LOHBLHCF_01930 7.2e-23
LOHBLHCF_01931 8.3e-23
LOHBLHCF_01932 5.9e-69 Q Collagen triple helix repeat (20 copies)
LOHBLHCF_01933 4.9e-93 M Glycosyltransferase like family
LOHBLHCF_01934 9.9e-121 H Methionine biosynthesis protein MetW
LOHBLHCF_01935 1.1e-195 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOHBLHCF_01936 3.2e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
LOHBLHCF_01937 1.3e-96 ynaD J Acetyltransferase (GNAT) domain
LOHBLHCF_01939 5.7e-73 S CAAX protease self-immunity
LOHBLHCF_01940 4.7e-08 S Uncharacterised protein family (UPF0715)
LOHBLHCF_01941 3.4e-22 K Cro/C1-type HTH DNA-binding domain
LOHBLHCF_01942 3.5e-117 ynaE S Domain of unknown function (DUF3885)
LOHBLHCF_01943 2.2e-39 ynaF
LOHBLHCF_01945 2e-77 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
LOHBLHCF_01946 7.9e-255 xynT G MFS/sugar transport protein
LOHBLHCF_01947 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
LOHBLHCF_01948 1e-215 xylR GK ROK family
LOHBLHCF_01949 4.4e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
LOHBLHCF_01950 2.5e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
LOHBLHCF_01951 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
LOHBLHCF_01952 9.4e-256 iolT EGP Major facilitator Superfamily
LOHBLHCF_01953 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LOHBLHCF_01954 2.2e-81 yncE S Protein of unknown function (DUF2691)
LOHBLHCF_01955 4.1e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LOHBLHCF_01958 1.9e-163 S Thymidylate synthase
LOHBLHCF_01960 1.6e-132 S Domain of unknown function, YrpD
LOHBLHCF_01963 7.9e-25 tatA U protein secretion
LOHBLHCF_01964 5.3e-71
LOHBLHCF_01965 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
LOHBLHCF_01968 1.6e-285 gerAA EG Spore germination protein
LOHBLHCF_01969 1.8e-193 gerAB U Spore germination
LOHBLHCF_01970 6.7e-218 gerLC S Spore germination protein
LOHBLHCF_01971 1.6e-151 yndG S DoxX-like family
LOHBLHCF_01972 2.1e-114 yndH S Domain of unknown function (DUF4166)
LOHBLHCF_01973 4.4e-305 yndJ S YndJ-like protein
LOHBLHCF_01975 5.8e-135 yndL S Replication protein
LOHBLHCF_01976 5.8e-74 yndM S Protein of unknown function (DUF2512)
LOHBLHCF_01977 1.9e-77 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LOHBLHCF_01978 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LOHBLHCF_01979 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LOHBLHCF_01980 9.2e-113 yneB L resolvase
LOHBLHCF_01981 1.3e-32 ynzC S UPF0291 protein
LOHBLHCF_01982 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LOHBLHCF_01983 4.8e-81 yneE S Sporulation inhibitor of replication protein sirA
LOHBLHCF_01984 1.8e-28 yneF S UPF0154 protein
LOHBLHCF_01985 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
LOHBLHCF_01986 1.2e-126 ccdA O cytochrome c biogenesis protein
LOHBLHCF_01987 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
LOHBLHCF_01988 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LOHBLHCF_01989 4.2e-74 yneK S Protein of unknown function (DUF2621)
LOHBLHCF_01990 2.2e-63 hspX O Spore coat protein
LOHBLHCF_01991 3.9e-19 sspP S Belongs to the SspP family
LOHBLHCF_01992 2.5e-14 sspO S Belongs to the SspO family
LOHBLHCF_01993 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LOHBLHCF_01994 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LOHBLHCF_01996 3.1e-08 sspN S Small acid-soluble spore protein N family
LOHBLHCF_01997 3.9e-35 tlp S Belongs to the Tlp family
LOHBLHCF_01998 1.2e-73 yneP S Thioesterase-like superfamily
LOHBLHCF_01999 2.2e-53 yneQ
LOHBLHCF_02000 4.1e-49 yneR S Belongs to the HesB IscA family
LOHBLHCF_02001 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LOHBLHCF_02002 6.6e-69 yccU S CoA-binding protein
LOHBLHCF_02003 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LOHBLHCF_02004 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LOHBLHCF_02005 2.3e-12
LOHBLHCF_02006 8.6e-57 ynfC
LOHBLHCF_02007 2.4e-251 agcS E Sodium alanine symporter
LOHBLHCF_02008 7.1e-283 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
LOHBLHCF_02010 6.9e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
LOHBLHCF_02011 1.4e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
LOHBLHCF_02012 2e-79 yngA S membrane
LOHBLHCF_02013 1.3e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LOHBLHCF_02014 5.5e-104 yngC S membrane-associated protein
LOHBLHCF_02015 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
LOHBLHCF_02016 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LOHBLHCF_02017 1.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LOHBLHCF_02018 7.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
LOHBLHCF_02019 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
LOHBLHCF_02020 4.7e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
LOHBLHCF_02021 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LOHBLHCF_02022 1.1e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
LOHBLHCF_02023 1.4e-23 S Family of unknown function (DUF5367)
LOHBLHCF_02024 3.8e-303 yngK T Glycosyl hydrolase-like 10
LOHBLHCF_02025 1.1e-63 yngL S Protein of unknown function (DUF1360)
LOHBLHCF_02026 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
LOHBLHCF_02027 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOHBLHCF_02028 2.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LOHBLHCF_02029 1.6e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
LOHBLHCF_02030 2.3e-246 yoeA V MATE efflux family protein
LOHBLHCF_02031 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
LOHBLHCF_02033 3.8e-96 L Integrase
LOHBLHCF_02034 3e-34 yoeD G Helix-turn-helix domain
LOHBLHCF_02035 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LOHBLHCF_02036 4.4e-155 gltR1 K Transcriptional regulator
LOHBLHCF_02037 1.3e-165 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LOHBLHCF_02038 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LOHBLHCF_02039 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
LOHBLHCF_02040 7.8e-155 gltC K Transcriptional regulator
LOHBLHCF_02041 1.1e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LOHBLHCF_02042 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOHBLHCF_02043 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LOHBLHCF_02044 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_02045 8.3e-40 yoxC S Bacterial protein of unknown function (DUF948)
LOHBLHCF_02046 2.9e-134 yoxB
LOHBLHCF_02047 1e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LOHBLHCF_02048 1.1e-234 yoaB EGP Major facilitator Superfamily
LOHBLHCF_02049 8.5e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
LOHBLHCF_02050 3.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOHBLHCF_02051 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOHBLHCF_02052 7.2e-33 yoaF
LOHBLHCF_02053 2.9e-08 ywlA S Uncharacterised protein family (UPF0715)
LOHBLHCF_02054 2.6e-13
LOHBLHCF_02055 7.7e-35 S Protein of unknown function (DUF4025)
LOHBLHCF_02056 5e-179 mcpU NT methyl-accepting chemotaxis protein
LOHBLHCF_02057 3.7e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
LOHBLHCF_02058 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
LOHBLHCF_02059 2.3e-111 yoaK S Membrane
LOHBLHCF_02060 2.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
LOHBLHCF_02061 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
LOHBLHCF_02064 2.1e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
LOHBLHCF_02067 8.9e-84
LOHBLHCF_02068 9.3e-172 yoaR V vancomycin resistance protein
LOHBLHCF_02069 2.8e-74 yoaS S Protein of unknown function (DUF2975)
LOHBLHCF_02070 4.4e-30 yozG K Transcriptional regulator
LOHBLHCF_02071 2.4e-147 yoaT S Protein of unknown function (DUF817)
LOHBLHCF_02072 1.1e-158 yoaU K LysR substrate binding domain
LOHBLHCF_02073 2.5e-158 yijE EG EamA-like transporter family
LOHBLHCF_02074 1.6e-76 yoaW
LOHBLHCF_02075 2.1e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LOHBLHCF_02076 2.4e-167 bla 3.5.2.6 V beta-lactamase
LOHBLHCF_02079 2.8e-238 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LOHBLHCF_02080 1.1e-139 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LOHBLHCF_02081 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
LOHBLHCF_02082 8.8e-37 S TM2 domain
LOHBLHCF_02084 1.3e-31 yoaF
LOHBLHCF_02085 2.6e-136
LOHBLHCF_02086 1.7e-16 FG Scavenger mRNA decapping enzyme C-term binding
LOHBLHCF_02093 3.7e-51 ynaF
LOHBLHCF_02094 1.6e-101 ynaE S Domain of unknown function (DUF3885)
LOHBLHCF_02095 9.4e-26 K Cro/C1-type HTH DNA-binding domain
LOHBLHCF_02096 6.2e-81 yoaW
LOHBLHCF_02097 2.9e-09 ywlA S Uncharacterised protein family (UPF0715)
LOHBLHCF_02099 5.8e-76
LOHBLHCF_02100 2.1e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
LOHBLHCF_02101 5e-17
LOHBLHCF_02103 3.1e-87 S response regulator aspartate phosphatase
LOHBLHCF_02105 3.7e-43 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LOHBLHCF_02106 5.7e-22 Q Methyltransferase
LOHBLHCF_02107 3.5e-35 2.7.7.73, 2.7.7.80 H ThiF family
LOHBLHCF_02108 2e-32 Q Methyltransferase domain
LOHBLHCF_02109 5.5e-26 G Major Facilitator Superfamily
LOHBLHCF_02110 3.4e-166 S impB/mucB/samB family C-terminal domain
LOHBLHCF_02111 1.5e-46 S YolD-like protein
LOHBLHCF_02112 1.4e-13
LOHBLHCF_02114 1.4e-33 J Acetyltransferase (GNAT) domain
LOHBLHCF_02115 4.1e-30 J Acetyltransferase (GNAT) domain
LOHBLHCF_02116 5.1e-99 yokK S SMI1 / KNR4 family
LOHBLHCF_02117 1.7e-73 S SMI1-KNR4 cell-wall
LOHBLHCF_02118 3e-86 S SMI1-KNR4 cell-wall
LOHBLHCF_02119 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LOHBLHCF_02120 1.3e-99 yokH G SMI1 / KNR4 family
LOHBLHCF_02121 2.6e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
LOHBLHCF_02122 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
LOHBLHCF_02123 1e-120 yobQ K helix_turn_helix, arabinose operon control protein
LOHBLHCF_02124 1e-139 yobR 2.3.1.1 J FR47-like protein
LOHBLHCF_02125 2.1e-97 yobS K Transcriptional regulator
LOHBLHCF_02126 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
LOHBLHCF_02127 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
LOHBLHCF_02128 2.5e-171 yobV K WYL domain
LOHBLHCF_02129 4.1e-90 yobW
LOHBLHCF_02130 1e-51 czrA K transcriptional
LOHBLHCF_02131 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LOHBLHCF_02132 1.5e-92 yozB S membrane
LOHBLHCF_02133 7e-144
LOHBLHCF_02134 1.2e-93 yocC
LOHBLHCF_02135 1.1e-186 yocD 3.4.17.13 V peptidase S66
LOHBLHCF_02136 6.9e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LOHBLHCF_02137 4.6e-197 desK 2.7.13.3 T Histidine kinase
LOHBLHCF_02138 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOHBLHCF_02139 6e-112 yocH CBM50 M COG1388 FOG LysM repeat
LOHBLHCF_02140 0.0 recQ 3.6.4.12 L DNA helicase
LOHBLHCF_02141 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LOHBLHCF_02142 3.3e-83 dksA T general stress protein
LOHBLHCF_02143 6.4e-54 yocL
LOHBLHCF_02144 2.8e-32
LOHBLHCF_02145 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
LOHBLHCF_02146 1.1e-40 yozN
LOHBLHCF_02147 1.9e-36 yocN
LOHBLHCF_02148 4.2e-56 yozO S Bacterial PH domain
LOHBLHCF_02149 2.7e-31 yozC
LOHBLHCF_02150 6.8e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
LOHBLHCF_02151 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
LOHBLHCF_02152 6e-165 sodA 1.15.1.1 P Superoxide dismutase
LOHBLHCF_02153 6e-228 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LOHBLHCF_02154 5.6e-167 yocS S -transporter
LOHBLHCF_02155 5.3e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LOHBLHCF_02156 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LOHBLHCF_02157 0.0 yojO P Von Willebrand factor
LOHBLHCF_02158 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
LOHBLHCF_02159 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LOHBLHCF_02160 7.9e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LOHBLHCF_02161 9e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
LOHBLHCF_02162 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LOHBLHCF_02164 1.6e-244 norM V Multidrug efflux pump
LOHBLHCF_02165 7.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LOHBLHCF_02166 3.7e-125 yojG S deacetylase
LOHBLHCF_02167 2.2e-60 yojF S Protein of unknown function (DUF1806)
LOHBLHCF_02168 1.5e-43
LOHBLHCF_02169 5.6e-161 rarD S -transporter
LOHBLHCF_02170 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
LOHBLHCF_02171 2.6e-09
LOHBLHCF_02172 3.5e-127 gntP EG COG2610 H gluconate symporter and related permeases
LOHBLHCF_02173 7e-61 gntP EG COG2610 H gluconate symporter and related permeases
LOHBLHCF_02174 4.7e-64 yodA S tautomerase
LOHBLHCF_02175 4.4e-55 yodB K transcriptional
LOHBLHCF_02176 4.1e-107 yodC C nitroreductase
LOHBLHCF_02177 2.1e-111 mhqD S Carboxylesterase
LOHBLHCF_02178 1.2e-171 yodE E COG0346 Lactoylglutathione lyase and related lyases
LOHBLHCF_02179 6.2e-28 S Protein of unknown function (DUF3311)
LOHBLHCF_02180 1.9e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOHBLHCF_02181 3.4e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LOHBLHCF_02182 2.4e-127 yodH Q Methyltransferase
LOHBLHCF_02183 1.5e-23 yodI
LOHBLHCF_02184 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LOHBLHCF_02185 1.2e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LOHBLHCF_02186 5.3e-09
LOHBLHCF_02187 3.6e-54 yodL S YodL-like
LOHBLHCF_02188 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
LOHBLHCF_02189 2.8e-24 yozD S YozD-like protein
LOHBLHCF_02191 6e-123 yodN
LOHBLHCF_02192 1.4e-36 yozE S Belongs to the UPF0346 family
LOHBLHCF_02193 2.9e-47 yokU S YokU-like protein, putative antitoxin
LOHBLHCF_02194 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
LOHBLHCF_02195 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
LOHBLHCF_02196 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
LOHBLHCF_02197 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LOHBLHCF_02198 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LOHBLHCF_02199 2.3e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LOHBLHCF_02201 5.9e-143 yiiD K acetyltransferase
LOHBLHCF_02202 3.6e-254 cgeD M maturation of the outermost layer of the spore
LOHBLHCF_02203 4.5e-38 cgeC
LOHBLHCF_02204 3.1e-63 cgeA
LOHBLHCF_02205 2e-177 cgeB S Spore maturation protein
LOHBLHCF_02206 1.4e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
LOHBLHCF_02207 2.1e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
LOHBLHCF_02209 9.8e-106 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LOHBLHCF_02216 2.8e-167 S Calcineurin-like phosphoesterase
LOHBLHCF_02217 2.5e-30 sspB S spore protein
LOHBLHCF_02220 1.4e-158 S Thymidylate synthase
LOHBLHCF_02223 4.9e-15 vanZ V COG4767 Glycopeptide antibiotics resistance protein
LOHBLHCF_02224 1.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LOHBLHCF_02225 1e-37 O Glutaredoxin
LOHBLHCF_02226 1.2e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOHBLHCF_02228 1.5e-95 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOHBLHCF_02230 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOHBLHCF_02231 6.8e-32 L GIY-YIG catalytic domain
LOHBLHCF_02232 2.4e-136 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
LOHBLHCF_02233 1.8e-63 S NrdI Flavodoxin like
LOHBLHCF_02242 1.2e-25 S hydrolase activity
LOHBLHCF_02245 4.3e-13
LOHBLHCF_02252 2e-80 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
LOHBLHCF_02257 8.1e-110 DR0488 S protein conserved in bacteria
LOHBLHCF_02258 0.0 2.7.7.7 L DNA polymerase
LOHBLHCF_02259 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LOHBLHCF_02260 8.5e-223 L DNA primase activity
LOHBLHCF_02261 1.3e-282 3.6.4.12 J DnaB-like helicase C terminal domain
LOHBLHCF_02262 4.5e-85
LOHBLHCF_02263 7.6e-180 L AAA domain
LOHBLHCF_02264 1.2e-155
LOHBLHCF_02270 1.2e-128 yoqW S Belongs to the SOS response-associated peptidase family
LOHBLHCF_02271 3e-145 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
LOHBLHCF_02272 1.4e-74
LOHBLHCF_02274 2.5e-82 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
LOHBLHCF_02278 8.3e-39
LOHBLHCF_02279 1.9e-49 S Protein of unknown function (DUF1273)
LOHBLHCF_02284 7.2e-10 S YopX protein
LOHBLHCF_02289 1.1e-33 K Transcriptional regulator
LOHBLHCF_02290 2.1e-177
LOHBLHCF_02291 2e-258 S DNA-sulfur modification-associated
LOHBLHCF_02292 6.8e-198 L Belongs to the 'phage' integrase family
LOHBLHCF_02297 1.9e-105
LOHBLHCF_02299 1.2e-14
LOHBLHCF_02300 1.6e-22
LOHBLHCF_02304 4.8e-08 ywlA S Uncharacterised protein family (UPF0715)
LOHBLHCF_02305 2e-53
LOHBLHCF_02306 4.8e-73 S Domain of unknown function (DUF4062)
LOHBLHCF_02307 2.6e-30 K Cro/C1-type HTH DNA-binding domain
LOHBLHCF_02308 6.2e-81 yoaW
LOHBLHCF_02309 1.9e-08 ywlA S Uncharacterised protein family (UPF0715)
LOHBLHCF_02310 5.3e-61 S Bacteriophage abortive infection AbiH
LOHBLHCF_02317 1.1e-204
LOHBLHCF_02318 4.3e-40
LOHBLHCF_02319 1e-42
LOHBLHCF_02322 0.0
LOHBLHCF_02323 2.3e-13 L GIY-YIG type nucleases (URI domain)
LOHBLHCF_02324 5.4e-79
LOHBLHCF_02325 1.6e-34 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LOHBLHCF_02327 1.2e-198 S Calcineurin-like phosphoesterase superfamily domain
LOHBLHCF_02329 2.2e-173
LOHBLHCF_02330 0.0 gp17a S Terminase-like family
LOHBLHCF_02331 9.4e-278
LOHBLHCF_02332 4e-254
LOHBLHCF_02333 7.8e-94
LOHBLHCF_02334 1.3e-185
LOHBLHCF_02335 1.1e-80
LOHBLHCF_02336 1.3e-64
LOHBLHCF_02338 6.5e-119
LOHBLHCF_02339 3.8e-90
LOHBLHCF_02340 8.1e-131
LOHBLHCF_02341 6.6e-89
LOHBLHCF_02344 5e-52
LOHBLHCF_02345 2.2e-10
LOHBLHCF_02346 3.3e-47
LOHBLHCF_02348 1.1e-81
LOHBLHCF_02349 7.5e-63
LOHBLHCF_02350 5.2e-123 xerH L Belongs to the 'phage' integrase family
LOHBLHCF_02352 1.4e-46
LOHBLHCF_02353 0.0 S peptidoglycan catabolic process
LOHBLHCF_02354 5.2e-144 S Phage tail protein
LOHBLHCF_02355 0.0 S Pfam Transposase IS66
LOHBLHCF_02356 3.9e-100
LOHBLHCF_02357 9.1e-54
LOHBLHCF_02359 3.3e-10 S Phage uncharacterised protein (Phage_XkdX)
LOHBLHCF_02360 2.2e-79 S N-acetylmuramoyl-L-alanine amidase activity
LOHBLHCF_02362 9.2e-37 S Bacteriophage holin
LOHBLHCF_02363 4.8e-93 S aspartate phosphatase
LOHBLHCF_02365 9.7e-74
LOHBLHCF_02366 2.6e-118 J tRNA cytidylyltransferase activity
LOHBLHCF_02367 3.8e-232 S impB/mucB/samB family C-terminal domain
LOHBLHCF_02368 1.7e-51 S YolD-like protein
LOHBLHCF_02369 4.8e-41
LOHBLHCF_02371 4e-09 S Domain of unknown function (DUF4879)
LOHBLHCF_02372 4.2e-80 S SMI1-KNR4 cell-wall
LOHBLHCF_02373 1.7e-172 yobL S Bacterial EndoU nuclease
LOHBLHCF_02374 1.6e-132 V HNH endonuclease
LOHBLHCF_02375 4.8e-67 G SMI1-KNR4 cell-wall
LOHBLHCF_02376 2.3e-35
LOHBLHCF_02377 8.7e-106 yokF 3.1.31.1 L RNA catabolic process
LOHBLHCF_02378 1.7e-80 yhbS S family acetyltransferase
LOHBLHCF_02382 8.4e-240 yokA L Recombinase
LOHBLHCF_02383 3.2e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
LOHBLHCF_02384 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LOHBLHCF_02385 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LOHBLHCF_02386 1.6e-70 ypoP K transcriptional
LOHBLHCF_02387 7.6e-223 mepA V MATE efflux family protein
LOHBLHCF_02388 1.6e-28 ypmT S Uncharacterized ympT
LOHBLHCF_02389 1.1e-98 ypmS S protein conserved in bacteria
LOHBLHCF_02390 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
LOHBLHCF_02391 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LOHBLHCF_02392 3.4e-39 ypmP S Protein of unknown function (DUF2535)
LOHBLHCF_02393 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LOHBLHCF_02394 4.7e-185 pspF K Transcriptional regulator
LOHBLHCF_02395 4.2e-110 hlyIII S protein, Hemolysin III
LOHBLHCF_02396 2.1e-111 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LOHBLHCF_02397 1.8e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LOHBLHCF_02398 1.1e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LOHBLHCF_02399 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LOHBLHCF_02400 7.8e-114 ypjP S YpjP-like protein
LOHBLHCF_02401 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
LOHBLHCF_02402 1.7e-75 yphP S Belongs to the UPF0403 family
LOHBLHCF_02403 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LOHBLHCF_02404 1.2e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
LOHBLHCF_02405 2.1e-106 ypgQ S phosphohydrolase
LOHBLHCF_02406 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LOHBLHCF_02407 8.1e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LOHBLHCF_02408 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LOHBLHCF_02409 7.9e-31 cspD K Cold-shock protein
LOHBLHCF_02410 3.8e-16 degR
LOHBLHCF_02411 8.1e-31 S Protein of unknown function (DUF2564)
LOHBLHCF_02412 4.1e-29 ypeQ S Zinc-finger
LOHBLHCF_02413 1.9e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
LOHBLHCF_02414 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LOHBLHCF_02415 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
LOHBLHCF_02417 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
LOHBLHCF_02418 2e-07
LOHBLHCF_02419 8.5e-38 ypbS S Protein of unknown function (DUF2533)
LOHBLHCF_02420 0.0 ypbR S Dynamin family
LOHBLHCF_02421 5.1e-87 ypbQ S protein conserved in bacteria
LOHBLHCF_02422 2.8e-207 bcsA Q Naringenin-chalcone synthase
LOHBLHCF_02423 3.3e-226 pbuX F xanthine
LOHBLHCF_02424 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LOHBLHCF_02425 1.3e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LOHBLHCF_02426 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LOHBLHCF_02427 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
LOHBLHCF_02428 1.9e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LOHBLHCF_02429 1.5e-186 ptxS K transcriptional
LOHBLHCF_02430 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LOHBLHCF_02431 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_02432 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
LOHBLHCF_02434 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LOHBLHCF_02435 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LOHBLHCF_02436 3.2e-95 ypsA S Belongs to the UPF0398 family
LOHBLHCF_02437 6.6e-237 yprB L RNase_H superfamily
LOHBLHCF_02438 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LOHBLHCF_02439 1.1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
LOHBLHCF_02440 1.2e-70 hspX O Belongs to the small heat shock protein (HSP20) family
LOHBLHCF_02441 1.2e-48 yppG S YppG-like protein
LOHBLHCF_02443 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
LOHBLHCF_02446 7.7e-185 yppC S Protein of unknown function (DUF2515)
LOHBLHCF_02447 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LOHBLHCF_02448 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
LOHBLHCF_02449 8.8e-92 ypoC
LOHBLHCF_02450 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LOHBLHCF_02451 5.7e-129 dnaD L DNA replication protein DnaD
LOHBLHCF_02452 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
LOHBLHCF_02453 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LOHBLHCF_02454 2.2e-79 ypmB S protein conserved in bacteria
LOHBLHCF_02455 6.7e-23 ypmA S Protein of unknown function (DUF4264)
LOHBLHCF_02456 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LOHBLHCF_02457 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LOHBLHCF_02458 1.2e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LOHBLHCF_02459 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LOHBLHCF_02460 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LOHBLHCF_02461 6.6e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LOHBLHCF_02462 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
LOHBLHCF_02463 3.4e-129 bshB1 S proteins, LmbE homologs
LOHBLHCF_02464 1.6e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
LOHBLHCF_02465 1.2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LOHBLHCF_02466 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
LOHBLHCF_02467 3.1e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
LOHBLHCF_02468 1.3e-142 ypjB S sporulation protein
LOHBLHCF_02469 6.8e-99 ypjA S membrane
LOHBLHCF_02470 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
LOHBLHCF_02471 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
LOHBLHCF_02472 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
LOHBLHCF_02473 4.2e-77 ypiF S Protein of unknown function (DUF2487)
LOHBLHCF_02474 2.8e-99 ypiB S Belongs to the UPF0302 family
LOHBLHCF_02475 1e-232 S COG0457 FOG TPR repeat
LOHBLHCF_02476 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LOHBLHCF_02477 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LOHBLHCF_02478 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LOHBLHCF_02479 1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LOHBLHCF_02480 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LOHBLHCF_02481 1.4e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
LOHBLHCF_02482 1.8e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LOHBLHCF_02483 1.8e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LOHBLHCF_02484 7.6e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LOHBLHCF_02485 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LOHBLHCF_02486 7.6e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LOHBLHCF_02487 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LOHBLHCF_02488 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
LOHBLHCF_02489 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LOHBLHCF_02490 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LOHBLHCF_02491 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LOHBLHCF_02492 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LOHBLHCF_02493 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LOHBLHCF_02494 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
LOHBLHCF_02495 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LOHBLHCF_02496 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LOHBLHCF_02497 6e-137 yphF
LOHBLHCF_02498 1.6e-18 yphE S Protein of unknown function (DUF2768)
LOHBLHCF_02499 3.6e-180 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LOHBLHCF_02500 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LOHBLHCF_02501 2.3e-27 ypzH
LOHBLHCF_02502 3.3e-161 seaA S YIEGIA protein
LOHBLHCF_02503 5.1e-102 yphA
LOHBLHCF_02504 3e-07 S YpzI-like protein
LOHBLHCF_02505 4.6e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LOHBLHCF_02506 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
LOHBLHCF_02507 8.9e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LOHBLHCF_02508 2.4e-23 S Family of unknown function (DUF5359)
LOHBLHCF_02509 2.1e-109 ypfA M Flagellar protein YcgR
LOHBLHCF_02510 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
LOHBLHCF_02511 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
LOHBLHCF_02512 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
LOHBLHCF_02513 8.1e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
LOHBLHCF_02514 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LOHBLHCF_02515 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LOHBLHCF_02516 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
LOHBLHCF_02517 2.8e-81 ypbF S Protein of unknown function (DUF2663)
LOHBLHCF_02518 2.2e-78 ypbE M Lysin motif
LOHBLHCF_02519 1.1e-99 ypbD S metal-dependent membrane protease
LOHBLHCF_02520 9.2e-286 recQ 3.6.4.12 L DNA helicase
LOHBLHCF_02521 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
LOHBLHCF_02522 4.7e-41 fer C Ferredoxin
LOHBLHCF_02523 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LOHBLHCF_02524 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOHBLHCF_02525 9.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LOHBLHCF_02526 1.8e-185 rsiX
LOHBLHCF_02527 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_02528 0.0 resE 2.7.13.3 T Histidine kinase
LOHBLHCF_02529 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_02530 2.6e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LOHBLHCF_02531 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
LOHBLHCF_02532 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LOHBLHCF_02533 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LOHBLHCF_02534 1.9e-87 spmB S Spore maturation protein
LOHBLHCF_02535 3.5e-103 spmA S Spore maturation protein
LOHBLHCF_02536 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
LOHBLHCF_02537 7.6e-97 ypuI S Protein of unknown function (DUF3907)
LOHBLHCF_02538 3.5e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LOHBLHCF_02539 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LOHBLHCF_02540 9.4e-92 ypuF S Domain of unknown function (DUF309)
LOHBLHCF_02541 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOHBLHCF_02542 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LOHBLHCF_02543 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LOHBLHCF_02544 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
LOHBLHCF_02545 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LOHBLHCF_02546 7.8e-55 ypuD
LOHBLHCF_02547 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LOHBLHCF_02548 5.6e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
LOHBLHCF_02550 4.2e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LOHBLHCF_02551 2e-36 S Pfam Transposase IS66
LOHBLHCF_02552 3e-07
LOHBLHCF_02557 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LOHBLHCF_02558 8.1e-149 ypuA S Secreted protein
LOHBLHCF_02559 7.5e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LOHBLHCF_02560 3.1e-273 spoVAF EG Stage V sporulation protein AF
LOHBLHCF_02561 1.4e-110 spoVAEA S stage V sporulation protein
LOHBLHCF_02562 2.2e-57 spoVAEB S stage V sporulation protein
LOHBLHCF_02563 3.4e-191 spoVAD I Stage V sporulation protein AD
LOHBLHCF_02564 2.3e-78 spoVAC S stage V sporulation protein AC
LOHBLHCF_02565 2.9e-67 spoVAB S Stage V sporulation protein AB
LOHBLHCF_02566 9.6e-112 spoVAA S Stage V sporulation protein AA
LOHBLHCF_02567 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOHBLHCF_02568 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LOHBLHCF_02569 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
LOHBLHCF_02570 5.3e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
LOHBLHCF_02571 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LOHBLHCF_02572 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LOHBLHCF_02573 2.6e-166 xerD L recombinase XerD
LOHBLHCF_02574 3.7e-37 S Protein of unknown function (DUF4227)
LOHBLHCF_02575 2.4e-80 fur P Belongs to the Fur family
LOHBLHCF_02576 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LOHBLHCF_02577 2.1e-29 yqkK
LOHBLHCF_02578 5.5e-242 mleA 1.1.1.38 C malic enzyme
LOHBLHCF_02579 1.1e-227 mleN C Na H antiporter
LOHBLHCF_02580 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
LOHBLHCF_02581 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
LOHBLHCF_02582 4.5e-58 ansR K Transcriptional regulator
LOHBLHCF_02583 1.8e-220 yqxK 3.6.4.12 L DNA helicase
LOHBLHCF_02584 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LOHBLHCF_02586 1.2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
LOHBLHCF_02587 3.1e-12 yqkE S Protein of unknown function (DUF3886)
LOHBLHCF_02588 2.1e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
LOHBLHCF_02589 9.4e-39 yqkC S Protein of unknown function (DUF2552)
LOHBLHCF_02590 2.8e-54 yqkB S Belongs to the HesB IscA family
LOHBLHCF_02591 9.8e-194 yqkA K GrpB protein
LOHBLHCF_02592 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
LOHBLHCF_02593 3.6e-87 yqjY K acetyltransferase
LOHBLHCF_02594 5.7e-50 S YolD-like protein
LOHBLHCF_02595 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOHBLHCF_02597 1.3e-224 yqjV G Major Facilitator Superfamily
LOHBLHCF_02599 7.9e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOHBLHCF_02600 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
LOHBLHCF_02601 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LOHBLHCF_02602 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_02603 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
LOHBLHCF_02604 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOHBLHCF_02605 2.7e-271 rocB E arginine degradation protein
LOHBLHCF_02606 2.9e-32 rocB E arginine degradation protein
LOHBLHCF_02607 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LOHBLHCF_02608 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LOHBLHCF_02609 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LOHBLHCF_02610 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LOHBLHCF_02611 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LOHBLHCF_02612 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LOHBLHCF_02613 1.1e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOHBLHCF_02614 4.5e-24 yqzJ
LOHBLHCF_02615 1.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LOHBLHCF_02616 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
LOHBLHCF_02617 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
LOHBLHCF_02618 4.2e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LOHBLHCF_02619 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
LOHBLHCF_02621 1.4e-98 yqjB S protein conserved in bacteria
LOHBLHCF_02622 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
LOHBLHCF_02623 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LOHBLHCF_02624 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
LOHBLHCF_02625 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
LOHBLHCF_02626 9.3e-77 yqiW S Belongs to the UPF0403 family
LOHBLHCF_02627 1.2e-163 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LOHBLHCF_02628 7.9e-208 norA EGP Major facilitator Superfamily
LOHBLHCF_02629 1.3e-151 bmrR K helix_turn_helix, mercury resistance
LOHBLHCF_02630 3.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LOHBLHCF_02631 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LOHBLHCF_02632 4.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LOHBLHCF_02633 1.1e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LOHBLHCF_02634 6e-202 buk 2.7.2.7 C Belongs to the acetokinase family
LOHBLHCF_02635 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
LOHBLHCF_02636 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
LOHBLHCF_02637 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
LOHBLHCF_02638 4e-34 yqzF S Protein of unknown function (DUF2627)
LOHBLHCF_02639 5.1e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LOHBLHCF_02640 4.5e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
LOHBLHCF_02641 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
LOHBLHCF_02642 1.3e-210 mmgC I acyl-CoA dehydrogenase
LOHBLHCF_02643 1.3e-154 hbdA 1.1.1.157 I Dehydrogenase
LOHBLHCF_02644 2.9e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
LOHBLHCF_02645 1.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LOHBLHCF_02646 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
LOHBLHCF_02647 5.9e-27
LOHBLHCF_02648 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LOHBLHCF_02650 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LOHBLHCF_02651 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
LOHBLHCF_02652 5.5e-306 recN L May be involved in recombinational repair of damaged DNA
LOHBLHCF_02653 1.1e-77 argR K Regulates arginine biosynthesis genes
LOHBLHCF_02654 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
LOHBLHCF_02655 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LOHBLHCF_02656 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LOHBLHCF_02657 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LOHBLHCF_02658 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LOHBLHCF_02659 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LOHBLHCF_02660 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LOHBLHCF_02661 2.1e-67 yqhY S protein conserved in bacteria
LOHBLHCF_02662 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LOHBLHCF_02663 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LOHBLHCF_02664 9.9e-91 spoIIIAH S SpoIIIAH-like protein
LOHBLHCF_02665 2.2e-109 spoIIIAG S stage III sporulation protein AG
LOHBLHCF_02666 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
LOHBLHCF_02667 2.2e-197 spoIIIAE S stage III sporulation protein AE
LOHBLHCF_02668 2.3e-58 spoIIIAD S Stage III sporulation protein AD
LOHBLHCF_02669 7.6e-29 spoIIIAC S stage III sporulation protein AC
LOHBLHCF_02670 4.1e-84 spoIIIAB S Stage III sporulation protein
LOHBLHCF_02671 4e-170 spoIIIAA S stage III sporulation protein AA
LOHBLHCF_02672 7.9e-37 yqhV S Protein of unknown function (DUF2619)
LOHBLHCF_02673 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LOHBLHCF_02674 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LOHBLHCF_02675 9.4e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
LOHBLHCF_02676 2.3e-93 yqhR S Conserved membrane protein YqhR
LOHBLHCF_02677 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
LOHBLHCF_02678 2.2e-61 yqhP
LOHBLHCF_02679 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
LOHBLHCF_02680 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LOHBLHCF_02681 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LOHBLHCF_02682 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
LOHBLHCF_02683 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LOHBLHCF_02684 7.1e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LOHBLHCF_02685 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LOHBLHCF_02686 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LOHBLHCF_02687 3e-150 yqhG S Bacterial protein YqhG of unknown function
LOHBLHCF_02688 3.6e-24 sinI S Anti-repressor SinI
LOHBLHCF_02689 1e-54 sinR K transcriptional
LOHBLHCF_02690 8.6e-142 tasA S Cell division protein FtsN
LOHBLHCF_02691 6.7e-59 sipW 3.4.21.89 U Signal peptidase
LOHBLHCF_02692 3.2e-109 yqxM
LOHBLHCF_02693 2.6e-52 yqzG S Protein of unknown function (DUF3889)
LOHBLHCF_02694 5.2e-26 yqzE S YqzE-like protein
LOHBLHCF_02695 1.2e-43 S ComG operon protein 7
LOHBLHCF_02696 4.1e-46 comGF U Putative Competence protein ComGF
LOHBLHCF_02697 3.1e-59 comGE
LOHBLHCF_02698 9.5e-66 gspH NU protein transport across the cell outer membrane
LOHBLHCF_02699 1.4e-47 comGC U Required for transformation and DNA binding
LOHBLHCF_02700 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
LOHBLHCF_02701 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LOHBLHCF_02702 1.4e-173 corA P Mg2 transporter protein
LOHBLHCF_02703 2e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LOHBLHCF_02704 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LOHBLHCF_02706 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
LOHBLHCF_02707 1.8e-37 yqgY S Protein of unknown function (DUF2626)
LOHBLHCF_02708 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LOHBLHCF_02709 8.9e-23 yqgW S Protein of unknown function (DUF2759)
LOHBLHCF_02710 6.9e-50 yqgV S Thiamine-binding protein
LOHBLHCF_02711 1.8e-198 yqgU
LOHBLHCF_02712 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
LOHBLHCF_02713 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOHBLHCF_02714 4.4e-180 glcK 2.7.1.2 G Glucokinase
LOHBLHCF_02715 4.3e-33 yqgQ S Protein conserved in bacteria
LOHBLHCF_02716 8.9e-236 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LOHBLHCF_02717 2.5e-09 yqgO
LOHBLHCF_02718 3.9e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LOHBLHCF_02719 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LOHBLHCF_02720 1.6e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
LOHBLHCF_02722 9.2e-51 yqzD
LOHBLHCF_02723 1.6e-71 yqzC S YceG-like family
LOHBLHCF_02724 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LOHBLHCF_02725 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LOHBLHCF_02726 4.4e-158 pstA P Phosphate transport system permease
LOHBLHCF_02727 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
LOHBLHCF_02728 7.6e-150 pstS P Phosphate
LOHBLHCF_02729 0.0 pbpA 3.4.16.4 M penicillin-binding protein
LOHBLHCF_02730 2.5e-231 yqgE EGP Major facilitator superfamily
LOHBLHCF_02731 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
LOHBLHCF_02732 4e-73 yqgC S protein conserved in bacteria
LOHBLHCF_02733 3.9e-131 yqgB S Protein of unknown function (DUF1189)
LOHBLHCF_02734 5.8e-46 yqfZ M LysM domain
LOHBLHCF_02735 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LOHBLHCF_02736 4.3e-62 yqfX S membrane
LOHBLHCF_02737 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
LOHBLHCF_02738 2.1e-76 zur P Belongs to the Fur family
LOHBLHCF_02739 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LOHBLHCF_02740 2.1e-36 yqfT S Protein of unknown function (DUF2624)
LOHBLHCF_02741 1.2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LOHBLHCF_02742 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LOHBLHCF_02743 3.5e-12 yqfQ S YqfQ-like protein
LOHBLHCF_02744 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LOHBLHCF_02745 1.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LOHBLHCF_02746 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
LOHBLHCF_02747 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
LOHBLHCF_02748 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LOHBLHCF_02749 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LOHBLHCF_02750 4.5e-88 yaiI S Belongs to the UPF0178 family
LOHBLHCF_02751 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LOHBLHCF_02752 4.5e-112 ccpN K CBS domain
LOHBLHCF_02753 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LOHBLHCF_02754 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LOHBLHCF_02755 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
LOHBLHCF_02756 8.4e-19 S YqzL-like protein
LOHBLHCF_02757 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LOHBLHCF_02758 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LOHBLHCF_02759 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LOHBLHCF_02760 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LOHBLHCF_02761 0.0 yqfF S membrane-associated HD superfamily hydrolase
LOHBLHCF_02763 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
LOHBLHCF_02764 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
LOHBLHCF_02765 2.7e-45 yqfC S sporulation protein YqfC
LOHBLHCF_02766 1e-24 yqfB
LOHBLHCF_02767 4.3e-122 yqfA S UPF0365 protein
LOHBLHCF_02768 6.5e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LOHBLHCF_02769 2.5e-61 yqeY S Yqey-like protein
LOHBLHCF_02770 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LOHBLHCF_02771 4.1e-157 yqeW P COG1283 Na phosphate symporter
LOHBLHCF_02772 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
LOHBLHCF_02773 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LOHBLHCF_02774 3e-173 prmA J Methylates ribosomal protein L11
LOHBLHCF_02775 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LOHBLHCF_02776 0.0 dnaK O Heat shock 70 kDa protein
LOHBLHCF_02777 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LOHBLHCF_02778 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LOHBLHCF_02779 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
LOHBLHCF_02780 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LOHBLHCF_02781 1e-51 yqxA S Protein of unknown function (DUF3679)
LOHBLHCF_02782 1.5e-222 spoIIP M stage II sporulation protein P
LOHBLHCF_02783 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LOHBLHCF_02784 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
LOHBLHCF_02785 4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
LOHBLHCF_02786 4.1e-15 S YqzM-like protein
LOHBLHCF_02787 0.0 comEC S Competence protein ComEC
LOHBLHCF_02788 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
LOHBLHCF_02789 3.9e-97 wza L COG1555 DNA uptake protein and related DNA-binding proteins
LOHBLHCF_02790 3.5e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOHBLHCF_02791 1.1e-138 yqeM Q Methyltransferase
LOHBLHCF_02792 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LOHBLHCF_02793 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LOHBLHCF_02794 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LOHBLHCF_02795 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
LOHBLHCF_02796 6.6e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LOHBLHCF_02797 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LOHBLHCF_02798 5.3e-95 yqeG S hydrolase of the HAD superfamily
LOHBLHCF_02800 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
LOHBLHCF_02801 8.9e-136 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOHBLHCF_02802 2.6e-104 yqeD S SNARE associated Golgi protein
LOHBLHCF_02803 4.7e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
LOHBLHCF_02804 2.8e-131 yqeB
LOHBLHCF_02805 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
LOHBLHCF_02806 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOHBLHCF_02807 3e-35 cisA2 L Recombinase
LOHBLHCF_02808 2e-68 psiE S Protein PsiE homolog
LOHBLHCF_02809 1.3e-235 yrkQ T Histidine kinase
LOHBLHCF_02810 4.1e-127 T Transcriptional regulator
LOHBLHCF_02811 1.5e-222 yrkO P Protein of unknown function (DUF418)
LOHBLHCF_02812 2.3e-104 yrkN K Acetyltransferase (GNAT) family
LOHBLHCF_02813 1.5e-97 ywrO S Flavodoxin-like fold
LOHBLHCF_02814 2.8e-79 S Protein of unknown function with HXXEE motif
LOHBLHCF_02815 1.4e-112 yrkJ S membrane transporter protein
LOHBLHCF_02816 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
LOHBLHCF_02817 1.3e-207 yrkH P Rhodanese Homology Domain
LOHBLHCF_02818 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
LOHBLHCF_02819 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
LOHBLHCF_02820 7.8e-39 yrkD S protein conserved in bacteria
LOHBLHCF_02821 2.3e-21
LOHBLHCF_02822 3.2e-106 yrkC G Cupin domain
LOHBLHCF_02823 1e-148 bltR K helix_turn_helix, mercury resistance
LOHBLHCF_02824 5.1e-210 blt EGP Major facilitator Superfamily
LOHBLHCF_02825 9.1e-83 bltD 2.3.1.57 K FR47-like protein
LOHBLHCF_02826 3.9e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LOHBLHCF_02827 8.7e-16 S YrzO-like protein
LOHBLHCF_02828 2.2e-60 yraO C Citrate transporter
LOHBLHCF_02829 2.4e-52 yraO C Citrate transporter
LOHBLHCF_02830 3.7e-162 yraN K Transcriptional regulator
LOHBLHCF_02831 6.5e-204 yraM S PrpF protein
LOHBLHCF_02832 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LOHBLHCF_02833 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOHBLHCF_02834 6e-154 S Alpha beta hydrolase
LOHBLHCF_02835 1.7e-60 T sh3 domain protein
LOHBLHCF_02836 2.4e-61 T sh3 domain protein
LOHBLHCF_02838 3.6e-64 E Glyoxalase-like domain
LOHBLHCF_02839 1.5e-36 yraG
LOHBLHCF_02840 6.4e-63 yraF M Spore coat protein
LOHBLHCF_02841 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LOHBLHCF_02842 7.5e-26 yraE
LOHBLHCF_02843 1.1e-49 yraD M Spore coat protein
LOHBLHCF_02844 1.3e-46 yraB K helix_turn_helix, mercury resistance
LOHBLHCF_02845 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
LOHBLHCF_02846 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
LOHBLHCF_02847 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
LOHBLHCF_02848 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
LOHBLHCF_02849 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LOHBLHCF_02850 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LOHBLHCF_02851 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
LOHBLHCF_02852 2.5e-74 levD 2.7.1.202 G PTS system fructose IIA component
LOHBLHCF_02853 0.0 levR K PTS system fructose IIA component
LOHBLHCF_02854 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
LOHBLHCF_02855 3.6e-106 yrhP E LysE type translocator
LOHBLHCF_02856 5.3e-150 yrhO K Archaeal transcriptional regulator TrmB
LOHBLHCF_02857 2.1e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_02858 2.7e-149 rsiV S Protein of unknown function (DUF3298)
LOHBLHCF_02859 0.0 yrhL I Acyltransferase family
LOHBLHCF_02860 3.3e-46 yrhK S YrhK-like protein
LOHBLHCF_02861 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LOHBLHCF_02862 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
LOHBLHCF_02863 2.8e-91 yrhH Q methyltransferase
LOHBLHCF_02866 6.7e-142 focA P Formate nitrite
LOHBLHCF_02867 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
LOHBLHCF_02868 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LOHBLHCF_02869 2.4e-78 yrhD S Protein of unknown function (DUF1641)
LOHBLHCF_02870 4.6e-35 yrhC S YrhC-like protein
LOHBLHCF_02871 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LOHBLHCF_02872 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
LOHBLHCF_02873 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LOHBLHCF_02874 3.2e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
LOHBLHCF_02875 1e-25 yrzA S Protein of unknown function (DUF2536)
LOHBLHCF_02876 1.6e-62 yrrS S Protein of unknown function (DUF1510)
LOHBLHCF_02877 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
LOHBLHCF_02878 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LOHBLHCF_02880 4.6e-12
LOHBLHCF_02883 1.8e-109 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOHBLHCF_02884 2.7e-57 S Bacteriophage holin family
LOHBLHCF_02886 4.5e-08
LOHBLHCF_02887 5.5e-75
LOHBLHCF_02890 5.8e-59
LOHBLHCF_02891 2.5e-242 NU Prophage endopeptidase tail
LOHBLHCF_02892 7.6e-112 S Phage tail protein
LOHBLHCF_02893 0.0 S peptidoglycan catabolic process
LOHBLHCF_02894 3.7e-10
LOHBLHCF_02895 6.8e-27
LOHBLHCF_02896 2.9e-60
LOHBLHCF_02897 1.1e-30
LOHBLHCF_02898 7.2e-49 S Bacteriophage HK97-gp10, putative tail-component
LOHBLHCF_02899 3.2e-24 S Phage gp6-like head-tail connector protein
LOHBLHCF_02900 1.6e-24 S peptidoglycan catabolic process
LOHBLHCF_02901 4.3e-07 S peptidoglycan catabolic process
LOHBLHCF_02902 2e-214 S peptidase activity
LOHBLHCF_02903 5.7e-104 S peptidase activity
LOHBLHCF_02904 8.4e-216 S Phage portal protein
LOHBLHCF_02905 2.2e-10
LOHBLHCF_02906 7.7e-220 S Phage Terminase
LOHBLHCF_02907 1e-69 S Phage terminase, small subunit
LOHBLHCF_02908 1.4e-19
LOHBLHCF_02909 2.5e-62 S HNH endonuclease
LOHBLHCF_02914 5.9e-73 L Phage integrase family
LOHBLHCF_02915 9e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
LOHBLHCF_02917 4.3e-59
LOHBLHCF_02921 1.6e-07 yqaO S Phage-like element PBSX protein XtrA
LOHBLHCF_02925 1.3e-30
LOHBLHCF_02927 9.1e-41 dnaC L IstB-like ATP binding protein
LOHBLHCF_02928 3.5e-67 ybl78 L Conserved phage C-terminus (Phg_2220_C)
LOHBLHCF_02931 1.6e-07 K Cupin domain
LOHBLHCF_02932 1.9e-28 K Helix-turn-helix XRE-family like proteins
LOHBLHCF_02934 3.2e-47
LOHBLHCF_02935 9e-63 L Arm DNA-binding domain
LOHBLHCF_02936 2e-112 udk 2.7.1.48 F Cytidine monophosphokinase
LOHBLHCF_02937 2.7e-246 yegQ O COG0826 Collagenase and related proteases
LOHBLHCF_02938 1.1e-172 yegQ O Peptidase U32
LOHBLHCF_02939 1.5e-118 yrrM 2.1.1.104 S O-methyltransferase
LOHBLHCF_02940 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LOHBLHCF_02941 1.2e-45 yrzB S Belongs to the UPF0473 family
LOHBLHCF_02942 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LOHBLHCF_02943 1.7e-41 yrzL S Belongs to the UPF0297 family
LOHBLHCF_02944 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LOHBLHCF_02945 1.3e-169 yrrI S AI-2E family transporter
LOHBLHCF_02946 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LOHBLHCF_02947 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
LOHBLHCF_02948 4e-108 gluC P ABC transporter
LOHBLHCF_02949 7.6e-107 glnP P ABC transporter
LOHBLHCF_02950 8e-08 S Protein of unknown function (DUF3918)
LOHBLHCF_02951 9.8e-31 yrzR
LOHBLHCF_02952 3.5e-82 yrrD S protein conserved in bacteria
LOHBLHCF_02953 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LOHBLHCF_02954 1.4e-15 S COG0457 FOG TPR repeat
LOHBLHCF_02955 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LOHBLHCF_02956 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
LOHBLHCF_02957 1.2e-70 cymR K Transcriptional regulator
LOHBLHCF_02958 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LOHBLHCF_02959 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LOHBLHCF_02960 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LOHBLHCF_02961 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
LOHBLHCF_02963 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
LOHBLHCF_02964 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LOHBLHCF_02965 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LOHBLHCF_02966 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LOHBLHCF_02967 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LOHBLHCF_02968 1.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
LOHBLHCF_02969 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
LOHBLHCF_02970 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LOHBLHCF_02971 1.6e-48 yrzD S Post-transcriptional regulator
LOHBLHCF_02972 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOHBLHCF_02973 1.3e-111 yrbG S membrane
LOHBLHCF_02974 2.2e-73 yrzE S Protein of unknown function (DUF3792)
LOHBLHCF_02975 8e-39 yajC U Preprotein translocase subunit YajC
LOHBLHCF_02976 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LOHBLHCF_02977 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LOHBLHCF_02978 2.6e-18 yrzS S Protein of unknown function (DUF2905)
LOHBLHCF_02979 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LOHBLHCF_02980 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LOHBLHCF_02981 4.8e-93 bofC S BofC C-terminal domain
LOHBLHCF_02982 4.5e-252 csbX EGP Major facilitator Superfamily
LOHBLHCF_02983 1.8e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
LOHBLHCF_02984 1.9e-118 yrzF T serine threonine protein kinase
LOHBLHCF_02986 2.3e-51 S Family of unknown function (DUF5412)
LOHBLHCF_02987 3.1e-262 alsT E Sodium alanine symporter
LOHBLHCF_02988 4.2e-127 yebC K transcriptional regulatory protein
LOHBLHCF_02989 1.3e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LOHBLHCF_02990 1.8e-156 safA M spore coat assembly protein SafA
LOHBLHCF_02991 1.2e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LOHBLHCF_02992 5.2e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
LOHBLHCF_02993 2.9e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LOHBLHCF_02994 4.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
LOHBLHCF_02995 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
LOHBLHCF_02996 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
LOHBLHCF_02997 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
LOHBLHCF_02998 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LOHBLHCF_02999 2.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
LOHBLHCF_03000 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LOHBLHCF_03001 4.1e-56 ysxB J ribosomal protein
LOHBLHCF_03002 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LOHBLHCF_03003 9.2e-161 spoIVFB S Stage IV sporulation protein
LOHBLHCF_03004 7.2e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
LOHBLHCF_03005 2.5e-144 minD D Belongs to the ParA family
LOHBLHCF_03006 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LOHBLHCF_03007 1.4e-84 mreD M shape-determining protein
LOHBLHCF_03008 1.1e-156 mreC M Involved in formation and maintenance of cell shape
LOHBLHCF_03009 1.8e-184 mreB D Rod shape-determining protein MreB
LOHBLHCF_03010 2.4e-51 radC E Belongs to the UPF0758 family
LOHBLHCF_03013 2.1e-27 K Helix-turn-helix domain
LOHBLHCF_03017 1.2e-12
LOHBLHCF_03019 5.2e-108 S aspartate phosphatase
LOHBLHCF_03020 2.4e-178 A Pre-toxin TG
LOHBLHCF_03021 4.8e-67 S Immunity protein 70
LOHBLHCF_03022 2.7e-132 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LOHBLHCF_03023 1.6e-31 xhlB S SPP1 phage holin
LOHBLHCF_03024 3e-28 bhlA S BhlA holin family
LOHBLHCF_03027 7.9e-55 S Domain of unknown function (DUF2479)
LOHBLHCF_03030 4.5e-59
LOHBLHCF_03031 7.7e-220 NU Prophage endopeptidase tail
LOHBLHCF_03032 1.5e-107 S Phage tail protein
LOHBLHCF_03033 0.0 D phage tail tape measure protein
LOHBLHCF_03036 2.6e-77 S Phage tail tube protein
LOHBLHCF_03038 1.8e-50 S Bacteriophage HK97-gp10, putative tail-component
LOHBLHCF_03039 3e-37 S Phage head-tail joining protein
LOHBLHCF_03040 4.8e-40 S Phage gp6-like head-tail connector protein
LOHBLHCF_03041 3.8e-20
LOHBLHCF_03042 6e-156 gp36 S capsid protein
LOHBLHCF_03043 3.4e-80 S peptidase activity
LOHBLHCF_03044 8.2e-174 S Phage portal protein
LOHBLHCF_03045 4.6e-305 S Terminase
LOHBLHCF_03046 6.8e-79 L phage terminase small subunit
LOHBLHCF_03047 1.4e-49 V HNH endonuclease
LOHBLHCF_03050 6.8e-29
LOHBLHCF_03051 3.4e-32 S YjcQ protein
LOHBLHCF_03052 1.5e-59
LOHBLHCF_03056 6.5e-61
LOHBLHCF_03059 1.2e-21 S YopX protein
LOHBLHCF_03061 9.5e-81
LOHBLHCF_03062 1.8e-93 S nuclease activity
LOHBLHCF_03063 1.8e-64
LOHBLHCF_03064 0.0 S hydrolase activity
LOHBLHCF_03065 2.1e-73 S Protein of unknown function (DUF669)
LOHBLHCF_03067 7.1e-167 tadZ D AAA domain
LOHBLHCF_03068 2e-92 S DNA protection
LOHBLHCF_03070 3.5e-21 S Uncharacterized protein YqaH
LOHBLHCF_03073 8.8e-09 plcR K helix-turn-helix
LOHBLHCF_03074 8.9e-64 S sequence-specific DNA binding
LOHBLHCF_03075 4.5e-71 S Pfam:Peptidase_M78
LOHBLHCF_03076 5.8e-229 S Recombinase
LOHBLHCF_03077 1.4e-66 radC E Belongs to the UPF0758 family
LOHBLHCF_03078 2.8e-102 maf D septum formation protein Maf
LOHBLHCF_03079 6.4e-166 spoIIB S Sporulation related domain
LOHBLHCF_03080 9.6e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LOHBLHCF_03081 7.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LOHBLHCF_03082 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LOHBLHCF_03083 1.6e-25
LOHBLHCF_03084 2.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LOHBLHCF_03085 7.6e-191 spoVID M stage VI sporulation protein D
LOHBLHCF_03086 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LOHBLHCF_03087 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
LOHBLHCF_03088 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LOHBLHCF_03089 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LOHBLHCF_03090 3.6e-146 hemX O cytochrome C
LOHBLHCF_03091 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LOHBLHCF_03092 5.4e-89 ysxD
LOHBLHCF_03093 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
LOHBLHCF_03094 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LOHBLHCF_03095 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
LOHBLHCF_03096 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LOHBLHCF_03097 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LOHBLHCF_03098 1.9e-186 ysoA H Tetratricopeptide repeat
LOHBLHCF_03099 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LOHBLHCF_03100 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LOHBLHCF_03101 1.8e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LOHBLHCF_03102 1.7e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LOHBLHCF_03103 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LOHBLHCF_03104 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
LOHBLHCF_03105 0.0 ilvB 2.2.1.6 E Acetolactate synthase
LOHBLHCF_03107 3.5e-79 ysnE K acetyltransferase
LOHBLHCF_03108 1.9e-159 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
LOHBLHCF_03109 1.7e-132 ysnF S protein conserved in bacteria
LOHBLHCF_03111 4.1e-92 ysnB S Phosphoesterase
LOHBLHCF_03112 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LOHBLHCF_03113 2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LOHBLHCF_03114 9.4e-195 gerM S COG5401 Spore germination protein
LOHBLHCF_03115 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LOHBLHCF_03116 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
LOHBLHCF_03117 3.3e-30 gerE K Transcriptional regulator
LOHBLHCF_03118 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
LOHBLHCF_03119 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LOHBLHCF_03120 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LOHBLHCF_03121 2.4e-107 sdhC C succinate dehydrogenase
LOHBLHCF_03122 1.2e-79 yslB S Protein of unknown function (DUF2507)
LOHBLHCF_03123 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LOHBLHCF_03124 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LOHBLHCF_03125 2e-52 trxA O Belongs to the thioredoxin family
LOHBLHCF_03126 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
LOHBLHCF_03128 2.1e-177 etfA C Electron transfer flavoprotein
LOHBLHCF_03129 4.5e-135 etfB C Electron transfer flavoprotein
LOHBLHCF_03130 4.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LOHBLHCF_03131 4e-99 fadR K Transcriptional regulator
LOHBLHCF_03132 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LOHBLHCF_03133 7.3e-68 yshE S membrane
LOHBLHCF_03134 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LOHBLHCF_03135 0.0 polX L COG1796 DNA polymerase IV (family X)
LOHBLHCF_03136 3.9e-85 cvpA S membrane protein, required for colicin V production
LOHBLHCF_03137 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LOHBLHCF_03138 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LOHBLHCF_03139 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LOHBLHCF_03140 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LOHBLHCF_03141 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOHBLHCF_03142 5.8e-32 sspI S Belongs to the SspI family
LOHBLHCF_03143 1.5e-203 ysfB KT regulator
LOHBLHCF_03144 3.3e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
LOHBLHCF_03145 5.8e-255 glcF C Glycolate oxidase
LOHBLHCF_03146 1e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
LOHBLHCF_03147 0.0 cstA T Carbon starvation protein
LOHBLHCF_03148 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
LOHBLHCF_03149 3.4e-144 araQ G transport system permease
LOHBLHCF_03150 4.2e-167 araP G carbohydrate transport
LOHBLHCF_03151 1.1e-253 araN G carbohydrate transport
LOHBLHCF_03152 2.8e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LOHBLHCF_03153 1.7e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LOHBLHCF_03154 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LOHBLHCF_03155 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
LOHBLHCF_03156 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LOHBLHCF_03157 1.5e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LOHBLHCF_03158 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
LOHBLHCF_03159 3.5e-67 ysdB S Sigma-w pathway protein YsdB
LOHBLHCF_03160 7.5e-45 ysdA S Membrane
LOHBLHCF_03161 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LOHBLHCF_03162 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LOHBLHCF_03163 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LOHBLHCF_03165 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LOHBLHCF_03166 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LOHBLHCF_03167 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
LOHBLHCF_03168 0.0 lytS 2.7.13.3 T Histidine kinase
LOHBLHCF_03169 1.1e-147 ysaA S HAD-hyrolase-like
LOHBLHCF_03170 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LOHBLHCF_03172 1.6e-157 ytxC S YtxC-like family
LOHBLHCF_03173 1.9e-107 ytxB S SNARE associated Golgi protein
LOHBLHCF_03174 1.5e-172 dnaI L Primosomal protein DnaI
LOHBLHCF_03175 8.5e-265 dnaB L Membrane attachment protein
LOHBLHCF_03176 3.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LOHBLHCF_03177 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LOHBLHCF_03178 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LOHBLHCF_03179 9.9e-67 ytcD K Transcriptional regulator
LOHBLHCF_03180 1.6e-203 ytbD EGP Major facilitator Superfamily
LOHBLHCF_03181 8.9e-161 ytbE S reductase
LOHBLHCF_03182 1.3e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LOHBLHCF_03183 1.1e-107 ytaF P Probably functions as a manganese efflux pump
LOHBLHCF_03184 7.8e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LOHBLHCF_03185 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOHBLHCF_03186 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
LOHBLHCF_03187 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_03188 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LOHBLHCF_03189 4.1e-242 icd 1.1.1.42 C isocitrate
LOHBLHCF_03190 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
LOHBLHCF_03191 4.7e-71 yeaL S membrane
LOHBLHCF_03192 4.4e-192 ytvI S sporulation integral membrane protein YtvI
LOHBLHCF_03193 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
LOHBLHCF_03194 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LOHBLHCF_03195 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LOHBLHCF_03196 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LOHBLHCF_03197 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LOHBLHCF_03198 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
LOHBLHCF_03199 0.0 dnaE 2.7.7.7 L DNA polymerase
LOHBLHCF_03200 3.2e-56 ytrH S Sporulation protein YtrH
LOHBLHCF_03201 8.2e-69 ytrI
LOHBLHCF_03202 9.2e-29
LOHBLHCF_03203 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
LOHBLHCF_03204 2.4e-47 ytpI S YtpI-like protein
LOHBLHCF_03205 8e-241 ytoI K transcriptional regulator containing CBS domains
LOHBLHCF_03206 1.7e-130 ytkL S Belongs to the UPF0173 family
LOHBLHCF_03207 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_03209 6.4e-265 argH 4.3.2.1 E argininosuccinate lyase
LOHBLHCF_03210 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LOHBLHCF_03211 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LOHBLHCF_03212 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOHBLHCF_03213 7e-165 ytxK 2.1.1.72 L DNA methylase
LOHBLHCF_03214 5.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LOHBLHCF_03215 8.7e-70 ytfJ S Sporulation protein YtfJ
LOHBLHCF_03216 2.1e-115 ytfI S Protein of unknown function (DUF2953)
LOHBLHCF_03217 8.5e-87 yteJ S RDD family
LOHBLHCF_03218 6e-180 sppA OU signal peptide peptidase SppA
LOHBLHCF_03219 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LOHBLHCF_03220 0.0 ytcJ S amidohydrolase
LOHBLHCF_03221 7.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LOHBLHCF_03222 2e-29 sspB S spore protein
LOHBLHCF_03223 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOHBLHCF_03224 8.6e-207 iscS2 2.8.1.7 E Cysteine desulfurase
LOHBLHCF_03225 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
LOHBLHCF_03226 2.7e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LOHBLHCF_03227 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LOHBLHCF_03228 3.4e-109 yttP K Transcriptional regulator
LOHBLHCF_03229 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LOHBLHCF_03230 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
LOHBLHCF_03231 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LOHBLHCF_03233 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LOHBLHCF_03234 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LOHBLHCF_03235 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LOHBLHCF_03236 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
LOHBLHCF_03237 6.1e-224 acuC BQ histone deacetylase
LOHBLHCF_03238 1.4e-125 motS N Flagellar motor protein
LOHBLHCF_03239 2.1e-146 motA N flagellar motor
LOHBLHCF_03240 1.7e-182 ccpA K catabolite control protein A
LOHBLHCF_03241 1.4e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LOHBLHCF_03242 7e-53 ytxJ O Protein of unknown function (DUF2847)
LOHBLHCF_03243 6.6e-17 ytxH S COG4980 Gas vesicle protein
LOHBLHCF_03244 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LOHBLHCF_03245 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LOHBLHCF_03246 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LOHBLHCF_03247 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LOHBLHCF_03248 9.8e-149 ytpQ S Belongs to the UPF0354 family
LOHBLHCF_03249 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LOHBLHCF_03250 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
LOHBLHCF_03251 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LOHBLHCF_03252 6.3e-51 ytzB S small secreted protein
LOHBLHCF_03253 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
LOHBLHCF_03254 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
LOHBLHCF_03255 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LOHBLHCF_03256 2e-45 ytzH S YtzH-like protein
LOHBLHCF_03257 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
LOHBLHCF_03258 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
LOHBLHCF_03259 7.2e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LOHBLHCF_03260 1.3e-165 ytlQ
LOHBLHCF_03261 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LOHBLHCF_03262 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LOHBLHCF_03263 2.7e-271 pepV 3.5.1.18 E Dipeptidase
LOHBLHCF_03264 7.2e-226 pbuO S permease
LOHBLHCF_03265 9.3e-201 ythQ U Bacterial ABC transporter protein EcsB
LOHBLHCF_03266 4.8e-131 ythP V ABC transporter
LOHBLHCF_03267 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
LOHBLHCF_03268 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LOHBLHCF_03269 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOHBLHCF_03270 8.2e-232 ytfP S HI0933-like protein
LOHBLHCF_03271 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LOHBLHCF_03272 3.1e-26 yteV S Sporulation protein Cse60
LOHBLHCF_03273 1.9e-113 yteU S Integral membrane protein
LOHBLHCF_03274 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
LOHBLHCF_03275 5.6e-71 yteS G transport
LOHBLHCF_03276 3.8e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LOHBLHCF_03277 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
LOHBLHCF_03278 0.0 ytdP K Transcriptional regulator
LOHBLHCF_03279 4.9e-287 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
LOHBLHCF_03280 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
LOHBLHCF_03281 3.6e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
LOHBLHCF_03282 3.1e-220 bioI 1.14.14.46 C Cytochrome P450
LOHBLHCF_03283 2.9e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LOHBLHCF_03284 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LOHBLHCF_03285 1.6e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LOHBLHCF_03286 1.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LOHBLHCF_03287 2e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LOHBLHCF_03288 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
LOHBLHCF_03289 2.5e-189 msmR K Transcriptional regulator
LOHBLHCF_03290 2.9e-243 msmE G Bacterial extracellular solute-binding protein
LOHBLHCF_03291 6.2e-168 amyD P ABC transporter
LOHBLHCF_03292 4.4e-144 amyC P ABC transporter (permease)
LOHBLHCF_03293 1.2e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LOHBLHCF_03294 2.1e-51 ytwF P Sulfurtransferase
LOHBLHCF_03295 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LOHBLHCF_03296 7.7e-55 ytvB S Protein of unknown function (DUF4257)
LOHBLHCF_03297 5.6e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LOHBLHCF_03298 6e-211 yttB EGP Major facilitator Superfamily
LOHBLHCF_03299 1.6e-41 yttA 2.7.13.3 S Pfam Transposase IS66
LOHBLHCF_03300 0.0 bceB V ABC transporter (permease)
LOHBLHCF_03301 1.1e-138 bceA V ABC transporter, ATP-binding protein
LOHBLHCF_03302 4e-184 T PhoQ Sensor
LOHBLHCF_03303 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_03304 2.1e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
LOHBLHCF_03305 9.1e-127 ytrE V ABC transporter, ATP-binding protein
LOHBLHCF_03306 1e-128
LOHBLHCF_03307 1.2e-151 P ABC-2 family transporter protein
LOHBLHCF_03308 4.2e-161 ytrB P abc transporter atp-binding protein
LOHBLHCF_03309 5.1e-66 ytrA K GntR family transcriptional regulator
LOHBLHCF_03311 6.7e-41 ytzC S Protein of unknown function (DUF2524)
LOHBLHCF_03312 1.8e-189 yhcC S Fe-S oxidoreductase
LOHBLHCF_03313 1.3e-105 ytqB J Putative rRNA methylase
LOHBLHCF_03314 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
LOHBLHCF_03315 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
LOHBLHCF_03316 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LOHBLHCF_03317 1.9e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
LOHBLHCF_03318 0.0 asnB 6.3.5.4 E Asparagine synthase
LOHBLHCF_03319 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LOHBLHCF_03320 2e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LOHBLHCF_03321 1.2e-38 ytmB S Protein of unknown function (DUF2584)
LOHBLHCF_03322 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LOHBLHCF_03323 1.8e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LOHBLHCF_03324 1.4e-144 ytlC P ABC transporter
LOHBLHCF_03325 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LOHBLHCF_03326 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LOHBLHCF_03327 7e-63 ytkC S Bacteriophage holin family
LOHBLHCF_03328 2.1e-76 dps P Belongs to the Dps family
LOHBLHCF_03330 1.1e-72 ytkA S YtkA-like
LOHBLHCF_03331 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LOHBLHCF_03332 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LOHBLHCF_03333 3.6e-41 rpmE2 J Ribosomal protein L31
LOHBLHCF_03334 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
LOHBLHCF_03335 1.5e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LOHBLHCF_03336 1.1e-24 S Domain of Unknown Function (DUF1540)
LOHBLHCF_03337 1.2e-147 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LOHBLHCF_03338 1.1e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LOHBLHCF_03339 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LOHBLHCF_03340 7.4e-169 troA P Belongs to the bacterial solute-binding protein 9 family
LOHBLHCF_03341 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LOHBLHCF_03342 4.7e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LOHBLHCF_03343 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LOHBLHCF_03344 1.1e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LOHBLHCF_03345 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LOHBLHCF_03346 2.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
LOHBLHCF_03347 2.6e-132 dksA T COG1734 DnaK suppressor protein
LOHBLHCF_03348 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
LOHBLHCF_03349 1.9e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOHBLHCF_03350 6.3e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
LOHBLHCF_03351 1.7e-232 ytcC M Glycosyltransferase Family 4
LOHBLHCF_03353 2.8e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
LOHBLHCF_03354 4.5e-216 cotSA M Glycosyl transferases group 1
LOHBLHCF_03355 2e-205 cotI S Spore coat protein
LOHBLHCF_03356 2.2e-76 tspO T membrane
LOHBLHCF_03357 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LOHBLHCF_03358 8.4e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
LOHBLHCF_03359 4.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
LOHBLHCF_03360 2.3e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LOHBLHCF_03361 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LOHBLHCF_03370 7.8e-08
LOHBLHCF_03371 1.3e-09
LOHBLHCF_03378 2e-08
LOHBLHCF_03383 3.4e-39 S COG NOG14552 non supervised orthologous group
LOHBLHCF_03384 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
LOHBLHCF_03385 5.8e-94 M1-753 M FR47-like protein
LOHBLHCF_03386 5.3e-188 yuaG 3.4.21.72 S protein conserved in bacteria
LOHBLHCF_03387 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
LOHBLHCF_03388 3.9e-84 yuaE S DinB superfamily
LOHBLHCF_03389 1.1e-106 yuaD
LOHBLHCF_03390 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
LOHBLHCF_03391 4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LOHBLHCF_03392 3.6e-94 yuaC K Belongs to the GbsR family
LOHBLHCF_03393 3.1e-90 yuaB
LOHBLHCF_03394 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
LOHBLHCF_03395 7.9e-236 ktrB P Potassium
LOHBLHCF_03396 1e-38 yiaA S yiaA/B two helix domain
LOHBLHCF_03397 1.1e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LOHBLHCF_03398 2e-275 yubD P Major Facilitator Superfamily
LOHBLHCF_03399 7.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
LOHBLHCF_03400 5.5e-45 S YolD-like protein
LOHBLHCF_03401 2e-07 S Protein of unknown function (DUF3800)
LOHBLHCF_03402 1.2e-27 K Helix-turn-helix domain
LOHBLHCF_03404 9e-41 S protein domain associated with
LOHBLHCF_03405 1.4e-102 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LOHBLHCF_03406 1.3e-56 S Bacteriophage holin family
LOHBLHCF_03407 2e-10 S Phage uncharacterised protein (Phage_XkdX)
LOHBLHCF_03409 2.7e-33
LOHBLHCF_03410 1.3e-60
LOHBLHCF_03411 3e-106 Z012_12235 S homolog of phage Mu protein gp47
LOHBLHCF_03412 4.8e-23 S Protein of unknown function (DUF2634)
LOHBLHCF_03413 4.7e-23
LOHBLHCF_03414 1e-88
LOHBLHCF_03415 2.4e-30
LOHBLHCF_03416 1e-40 3.5.1.28 M LysM domain
LOHBLHCF_03417 4.8e-139 N phage tail tape measure protein
LOHBLHCF_03418 3.6e-16
LOHBLHCF_03419 1.8e-34
LOHBLHCF_03420 1e-102 Z012_02110 S Protein of unknown function (DUF3383)
LOHBLHCF_03421 7e-30
LOHBLHCF_03422 4e-23
LOHBLHCF_03423 3.6e-48
LOHBLHCF_03424 2.4e-16 S Phage gp6-like head-tail connector protein
LOHBLHCF_03425 1.3e-32 S Phage Mu protein F like protein
LOHBLHCF_03427 1.9e-111 S Phage capsid family
LOHBLHCF_03428 5.9e-63 S Domain of unknown function (DUF4355)
LOHBLHCF_03430 9.8e-157 S Phage portal protein, SPP1 Gp6-like
LOHBLHCF_03431 2.6e-185 ps334 S Terminase-like family
LOHBLHCF_03432 7.8e-81 yqaS L DNA packaging
LOHBLHCF_03436 8.9e-17 K Transcriptional regulator
LOHBLHCF_03438 2.6e-70 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LOHBLHCF_03442 5.3e-08 S YopX protein
LOHBLHCF_03444 1.6e-106 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
LOHBLHCF_03446 6.9e-26
LOHBLHCF_03448 1.7e-25 yqaO S Phage-like element PBSX protein XtrA
LOHBLHCF_03450 1.3e-52 S Protein of unknown function (DUF1064)
LOHBLHCF_03451 1.3e-07
LOHBLHCF_03453 1.5e-80 xkdC L IstB-like ATP binding protein
LOHBLHCF_03454 3.4e-25 L DnaD domain protein
LOHBLHCF_03455 4.9e-135 recT L RecT family
LOHBLHCF_03456 8.5e-152 yqaJ L YqaJ-like viral recombinase domain
LOHBLHCF_03461 1.9e-82
LOHBLHCF_03462 4.5e-50 kilA K SOS response
LOHBLHCF_03463 5.8e-15 S Helix-turn-helix domain
LOHBLHCF_03464 1.3e-16 K Helix-turn-helix XRE-family like proteins
LOHBLHCF_03465 4e-18 xre K Helix-turn-helix XRE-family like proteins
LOHBLHCF_03466 1.5e-49
LOHBLHCF_03467 4.7e-23 S Protein of unknown function (DUF4064)
LOHBLHCF_03468 2.5e-49 xkdA E IrrE N-terminal-like domain
LOHBLHCF_03469 2.4e-167 L Belongs to the 'phage' integrase family
LOHBLHCF_03471 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LOHBLHCF_03472 9.1e-196 yubA S transporter activity
LOHBLHCF_03473 6.3e-182 ygjR S Oxidoreductase
LOHBLHCF_03474 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
LOHBLHCF_03475 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
LOHBLHCF_03476 5.1e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LOHBLHCF_03477 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
LOHBLHCF_03478 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
LOHBLHCF_03480 2.1e-237 mcpA NT chemotaxis protein
LOHBLHCF_03481 5.5e-294 mcpA NT chemotaxis protein
LOHBLHCF_03482 1.1e-217 mcpA NT chemotaxis protein
LOHBLHCF_03483 3.5e-224 mcpA NT chemotaxis protein
LOHBLHCF_03484 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
LOHBLHCF_03485 1e-35
LOHBLHCF_03486 3.1e-71 yugU S Uncharacterised protein family UPF0047
LOHBLHCF_03487 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
LOHBLHCF_03488 3.2e-234 yugS S COG1253 Hemolysins and related proteins containing CBS domains
LOHBLHCF_03489 1.4e-116 yugP S Zn-dependent protease
LOHBLHCF_03490 2.3e-38
LOHBLHCF_03491 5.4e-53 mstX S Membrane-integrating protein Mistic
LOHBLHCF_03492 2.2e-182 yugO P COG1226 Kef-type K transport systems
LOHBLHCF_03493 1.3e-72 yugN S YugN-like family
LOHBLHCF_03495 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
LOHBLHCF_03496 1.1e-228 yugK C Dehydrogenase
LOHBLHCF_03497 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
LOHBLHCF_03498 1.1e-34 yuzA S Domain of unknown function (DUF378)
LOHBLHCF_03499 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
LOHBLHCF_03500 2.1e-199 yugH 2.6.1.1 E Aminotransferase
LOHBLHCF_03501 1.6e-85 alaR K Transcriptional regulator
LOHBLHCF_03502 4.6e-154 yugF I Hydrolase
LOHBLHCF_03503 1.1e-40 yugE S Domain of unknown function (DUF1871)
LOHBLHCF_03504 7.6e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LOHBLHCF_03505 2.1e-230 T PhoQ Sensor
LOHBLHCF_03506 3.7e-69 kapB G Kinase associated protein B
LOHBLHCF_03507 4.2e-115 kapD L the KinA pathway to sporulation
LOHBLHCF_03509 2.1e-183 yuxJ EGP Major facilitator Superfamily
LOHBLHCF_03510 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
LOHBLHCF_03511 1.8e-74 yuxK S protein conserved in bacteria
LOHBLHCF_03512 6.3e-78 yufK S Family of unknown function (DUF5366)
LOHBLHCF_03513 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LOHBLHCF_03514 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
LOHBLHCF_03515 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LOHBLHCF_03516 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LOHBLHCF_03517 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
LOHBLHCF_03518 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
LOHBLHCF_03519 1.3e-233 maeN C COG3493 Na citrate symporter
LOHBLHCF_03520 3.2e-14
LOHBLHCF_03521 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LOHBLHCF_03522 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOHBLHCF_03523 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOHBLHCF_03524 8.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOHBLHCF_03525 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOHBLHCF_03526 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOHBLHCF_03527 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
LOHBLHCF_03528 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
LOHBLHCF_03529 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOHBLHCF_03530 0.0 comP 2.7.13.3 T Histidine kinase
LOHBLHCF_03532 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
LOHBLHCF_03535 3.2e-22 yuzC
LOHBLHCF_03536 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
LOHBLHCF_03537 8e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LOHBLHCF_03538 1.2e-102 pncA Q COG1335 Amidases related to nicotinamidase
LOHBLHCF_03539 5.1e-66 yueI S Protein of unknown function (DUF1694)
LOHBLHCF_03540 7.4e-39 yueH S YueH-like protein
LOHBLHCF_03541 6.6e-31 yueG S Spore germination protein gerPA/gerPF
LOHBLHCF_03542 3.2e-190 yueF S transporter activity
LOHBLHCF_03543 5.2e-71 S Protein of unknown function (DUF2283)
LOHBLHCF_03544 2.9e-24 S Protein of unknown function (DUF2642)
LOHBLHCF_03545 4.8e-96 yueE S phosphohydrolase
LOHBLHCF_03546 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_03547 3.3e-64 yueC S Family of unknown function (DUF5383)
LOHBLHCF_03548 0.0 esaA S type VII secretion protein EsaA
LOHBLHCF_03549 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LOHBLHCF_03550 5.7e-210 essB S WXG100 protein secretion system (Wss), protein YukC
LOHBLHCF_03551 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
LOHBLHCF_03552 2.8e-45 esxA S Belongs to the WXG100 family
LOHBLHCF_03553 4.7e-227 yukF QT Transcriptional regulator
LOHBLHCF_03554 5.2e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LOHBLHCF_03555 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
LOHBLHCF_03556 5e-36 mbtH S MbtH-like protein
LOHBLHCF_03557 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOHBLHCF_03558 1.2e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
LOHBLHCF_03559 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
LOHBLHCF_03560 6.2e-224 entC 5.4.4.2 HQ Isochorismate synthase
LOHBLHCF_03561 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_03562 9.6e-166 besA S Putative esterase
LOHBLHCF_03563 8.3e-121 yuiH S Oxidoreductase molybdopterin binding domain
LOHBLHCF_03564 1.3e-92 bioY S Biotin biosynthesis protein
LOHBLHCF_03565 8.7e-211 yuiF S antiporter
LOHBLHCF_03566 2.5e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LOHBLHCF_03567 1.2e-77 yuiD S protein conserved in bacteria
LOHBLHCF_03568 1.4e-116 yuiC S protein conserved in bacteria
LOHBLHCF_03569 8.4e-27 yuiB S Putative membrane protein
LOHBLHCF_03570 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
LOHBLHCF_03571 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
LOHBLHCF_03573 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LOHBLHCF_03574 1.9e-115 paiB K Putative FMN-binding domain
LOHBLHCF_03575 2.3e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOHBLHCF_03576 3.7e-63 erpA S Belongs to the HesB IscA family
LOHBLHCF_03577 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LOHBLHCF_03578 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOHBLHCF_03579 3.2e-39 yuzB S Belongs to the UPF0349 family
LOHBLHCF_03580 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
LOHBLHCF_03581 3e-56 yuzD S protein conserved in bacteria
LOHBLHCF_03582 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
LOHBLHCF_03583 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
LOHBLHCF_03584 9.5e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LOHBLHCF_03585 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LOHBLHCF_03586 1e-240 hom 1.1.1.3 E homoserine dehydrogenase
LOHBLHCF_03587 6.5e-198 yutH S Spore coat protein
LOHBLHCF_03588 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LOHBLHCF_03589 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LOHBLHCF_03590 8.6e-75 yutE S Protein of unknown function DUF86
LOHBLHCF_03591 9.7e-48 yutD S protein conserved in bacteria
LOHBLHCF_03592 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LOHBLHCF_03593 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LOHBLHCF_03594 4.5e-196 lytH M Peptidase, M23
LOHBLHCF_03595 3.9e-131 yunB S Sporulation protein YunB (Spo_YunB)
LOHBLHCF_03596 4.8e-48 yunC S Domain of unknown function (DUF1805)
LOHBLHCF_03597 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LOHBLHCF_03598 2e-141 yunE S membrane transporter protein
LOHBLHCF_03599 4.3e-171 yunF S Protein of unknown function DUF72
LOHBLHCF_03600 6.9e-59 yunG
LOHBLHCF_03601 9.6e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LOHBLHCF_03602 1.6e-299 pucR QT COG2508 Regulator of polyketide synthase expression
LOHBLHCF_03603 2.2e-233 pbuX F Permease family
LOHBLHCF_03604 2.8e-222 pbuX F xanthine
LOHBLHCF_03605 3.7e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LOHBLHCF_03606 3.5e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LOHBLHCF_03608 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LOHBLHCF_03609 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LOHBLHCF_03610 2.9e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LOHBLHCF_03611 5.3e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
LOHBLHCF_03612 2.6e-183 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LOHBLHCF_03613 1.6e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LOHBLHCF_03614 7.5e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LOHBLHCF_03615 3.5e-168 bsn L Ribonuclease
LOHBLHCF_03616 8.5e-204 msmX P Belongs to the ABC transporter superfamily
LOHBLHCF_03617 3.3e-135 yurK K UTRA
LOHBLHCF_03618 9.7e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
LOHBLHCF_03619 1.6e-168 yurM P COG0395 ABC-type sugar transport system, permease component
LOHBLHCF_03620 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
LOHBLHCF_03621 7.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
LOHBLHCF_03622 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LOHBLHCF_03623 3.7e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
LOHBLHCF_03624 1.2e-205 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LOHBLHCF_03626 1e-41
LOHBLHCF_03627 4.2e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOHBLHCF_03628 3.5e-271 sufB O FeS cluster assembly
LOHBLHCF_03629 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
LOHBLHCF_03630 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LOHBLHCF_03631 4.5e-244 sufD O assembly protein SufD
LOHBLHCF_03632 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LOHBLHCF_03633 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LOHBLHCF_03634 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
LOHBLHCF_03635 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
LOHBLHCF_03636 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LOHBLHCF_03637 2.4e-56 yusD S SCP-2 sterol transfer family
LOHBLHCF_03638 1.2e-54 traF CO Thioredoxin
LOHBLHCF_03639 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
LOHBLHCF_03640 1.1e-39 yusG S Protein of unknown function (DUF2553)
LOHBLHCF_03641 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LOHBLHCF_03642 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
LOHBLHCF_03643 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
LOHBLHCF_03644 6.1e-216 fadA 2.3.1.16 I Belongs to the thiolase family
LOHBLHCF_03645 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
LOHBLHCF_03646 8.1e-09 S YuzL-like protein
LOHBLHCF_03647 1.2e-163 fadM E Proline dehydrogenase
LOHBLHCF_03648 5.1e-40
LOHBLHCF_03649 5.4e-53 yusN M Coat F domain
LOHBLHCF_03650 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
LOHBLHCF_03651 1.2e-291 yusP P Major facilitator superfamily
LOHBLHCF_03652 4.6e-64 yusQ S Tautomerase enzyme
LOHBLHCF_03653 3.6e-105 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_03654 5.7e-158 yusT K LysR substrate binding domain
LOHBLHCF_03655 5.6e-39 yusU S Protein of unknown function (DUF2573)
LOHBLHCF_03656 5.1e-153 yusV 3.6.3.34 HP ABC transporter
LOHBLHCF_03657 2.5e-66 S YusW-like protein
LOHBLHCF_03658 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
LOHBLHCF_03659 1.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_03660 1.8e-78 dps P Ferritin-like domain
LOHBLHCF_03661 6.2e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOHBLHCF_03662 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_03663 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
LOHBLHCF_03664 4.3e-158 yuxN K Transcriptional regulator
LOHBLHCF_03665 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LOHBLHCF_03666 3.9e-24 S Protein of unknown function (DUF3970)
LOHBLHCF_03667 1.3e-244 gerAA EG Spore germination protein
LOHBLHCF_03668 3.8e-196 gerAB E Spore germination protein
LOHBLHCF_03669 5e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
LOHBLHCF_03670 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOHBLHCF_03671 1.6e-186 vraS 2.7.13.3 T Histidine kinase
LOHBLHCF_03672 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LOHBLHCF_03673 1.2e-123 liaG S Putative adhesin
LOHBLHCF_03674 5.6e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LOHBLHCF_03675 1.6e-61 liaI S membrane
LOHBLHCF_03676 1.4e-226 yvqJ EGP Major facilitator Superfamily
LOHBLHCF_03677 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
LOHBLHCF_03678 5.4e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LOHBLHCF_03679 1.7e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_03680 6.5e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LOHBLHCF_03681 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_03682 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
LOHBLHCF_03683 0.0 T PhoQ Sensor
LOHBLHCF_03684 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_03685 3.6e-22
LOHBLHCF_03686 1.6e-97 yvrI K RNA polymerase
LOHBLHCF_03687 2.4e-19 S YvrJ protein family
LOHBLHCF_03688 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
LOHBLHCF_03689 1.3e-64 yvrL S Regulatory protein YrvL
LOHBLHCF_03690 9e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
LOHBLHCF_03691 7.9e-123 macB V ABC transporter, ATP-binding protein
LOHBLHCF_03692 9e-175 M Efflux transporter rnd family, mfp subunit
LOHBLHCF_03693 2.9e-148 fhuC 3.6.3.34 HP ABC transporter
LOHBLHCF_03694 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_03695 1.1e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOHBLHCF_03696 7.6e-177 fhuD P ABC transporter
LOHBLHCF_03697 1.8e-235 yvsH E Arginine ornithine antiporter
LOHBLHCF_03698 6.5e-16 S Small spore protein J (Spore_SspJ)
LOHBLHCF_03699 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
LOHBLHCF_03700 1.9e-97 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOHBLHCF_03701 2.2e-201 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOHBLHCF_03702 2.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
LOHBLHCF_03703 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
LOHBLHCF_03704 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
LOHBLHCF_03705 1.1e-155 yvgN S reductase
LOHBLHCF_03706 2.1e-85 yvgO
LOHBLHCF_03707 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
LOHBLHCF_03708 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LOHBLHCF_03709 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LOHBLHCF_03710 0.0 helD 3.6.4.12 L DNA helicase
LOHBLHCF_03712 1.6e-106 yvgT S membrane
LOHBLHCF_03713 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
LOHBLHCF_03714 1.6e-104 bdbD O Thioredoxin
LOHBLHCF_03715 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LOHBLHCF_03716 0.0 copA 3.6.3.54 P P-type ATPase
LOHBLHCF_03717 5.9e-29 copZ P Copper resistance protein CopZ
LOHBLHCF_03718 2.2e-48 csoR S transcriptional
LOHBLHCF_03719 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
LOHBLHCF_03720 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LOHBLHCF_03721 0.0 yvaC S Fusaric acid resistance protein-like
LOHBLHCF_03722 9.7e-73 yvaD S Family of unknown function (DUF5360)
LOHBLHCF_03723 1.8e-54 yvaE P Small Multidrug Resistance protein
LOHBLHCF_03724 8.6e-99 K Bacterial regulatory proteins, tetR family
LOHBLHCF_03725 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_03726 5.3e-15
LOHBLHCF_03729 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LOHBLHCF_03730 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LOHBLHCF_03731 5.6e-143 est 3.1.1.1 S Carboxylesterase
LOHBLHCF_03732 2.4e-23 secG U Preprotein translocase subunit SecG
LOHBLHCF_03733 5.9e-151 yvaM S Serine aminopeptidase, S33
LOHBLHCF_03734 9.8e-36 yvzC K Transcriptional
LOHBLHCF_03735 4e-69 K transcriptional
LOHBLHCF_03736 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
LOHBLHCF_03737 2.2e-54 yodB K transcriptional
LOHBLHCF_03738 4.2e-218 NT chemotaxis protein
LOHBLHCF_03739 8.6e-153 T His Kinase A (phosphoacceptor) domain
LOHBLHCF_03740 2.5e-105 K Transcriptional regulatory protein, C terminal
LOHBLHCF_03741 1.7e-81 mutG S ABC-2 family transporter protein
LOHBLHCF_03742 1.5e-87 spaE S ABC-2 family transporter protein
LOHBLHCF_03743 4.2e-103 mutF V ABC transporter, ATP-binding protein
LOHBLHCF_03745 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
LOHBLHCF_03746 2.1e-95 spaC2 V PFAM Lanthionine synthetase
LOHBLHCF_03747 1.3e-156 spaT V ABC transporter
LOHBLHCF_03748 5.3e-195 spaB S Lantibiotic dehydratase, C terminus
LOHBLHCF_03749 1.4e-103 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LOHBLHCF_03750 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LOHBLHCF_03751 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LOHBLHCF_03752 6.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LOHBLHCF_03753 3.3e-60 yvbF K Belongs to the GbsR family
LOHBLHCF_03754 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LOHBLHCF_03755 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LOHBLHCF_03756 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LOHBLHCF_03757 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LOHBLHCF_03758 1.3e-96 yvbF K Belongs to the GbsR family
LOHBLHCF_03759 6.4e-103 yvbG U UPF0056 membrane protein
LOHBLHCF_03760 1.9e-112 yvbH S YvbH-like oligomerisation region
LOHBLHCF_03761 2.3e-122 exoY M Membrane
LOHBLHCF_03762 0.0 tcaA S response to antibiotic
LOHBLHCF_03763 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
LOHBLHCF_03764 1.3e-173 EGP Major facilitator Superfamily
LOHBLHCF_03765 3.7e-152
LOHBLHCF_03766 1.5e-113 S GlcNAc-PI de-N-acetylase
LOHBLHCF_03767 9.2e-122 C WbqC-like protein family
LOHBLHCF_03768 4.5e-114 M Protein involved in cellulose biosynthesis
LOHBLHCF_03769 7.9e-158 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LOHBLHCF_03770 2.1e-147 5.1.3.2 M GDP-mannose 4,6 dehydratase
LOHBLHCF_03771 5.7e-187 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LOHBLHCF_03772 2.8e-217 1.1.1.136 M UDP binding domain
LOHBLHCF_03773 6.9e-165 ywaD 3.4.11.10, 3.4.11.6 S PA domain
LOHBLHCF_03774 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LOHBLHCF_03775 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LOHBLHCF_03776 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LOHBLHCF_03777 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LOHBLHCF_03778 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LOHBLHCF_03779 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LOHBLHCF_03780 1.6e-252 araE EGP Major facilitator Superfamily
LOHBLHCF_03781 5.5e-203 araR K transcriptional
LOHBLHCF_03782 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOHBLHCF_03783 5.1e-159 yvbU K Transcriptional regulator
LOHBLHCF_03784 7.2e-156 yvbV EG EamA-like transporter family
LOHBLHCF_03785 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LOHBLHCF_03786 1.9e-184 yvbX S Glycosyl hydrolase
LOHBLHCF_03787 7.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LOHBLHCF_03788 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LOHBLHCF_03789 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LOHBLHCF_03790 1.3e-44 S Protein of unknown function (DUF2812)
LOHBLHCF_03791 2.6e-31 K Transcriptional regulator PadR-like family
LOHBLHCF_03792 6.5e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOHBLHCF_03793 2.4e-193 desK 2.7.13.3 T Histidine kinase
LOHBLHCF_03794 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
LOHBLHCF_03795 4.4e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
LOHBLHCF_03797 6.4e-156 rsbQ S Alpha/beta hydrolase family
LOHBLHCF_03798 1.8e-199 rsbU 3.1.3.3 T response regulator
LOHBLHCF_03799 1.9e-250 galA 3.2.1.89 G arabinogalactan
LOHBLHCF_03800 0.0 lacA 3.2.1.23 G beta-galactosidase
LOHBLHCF_03801 7.2e-150 ganQ P transport
LOHBLHCF_03802 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
LOHBLHCF_03803 1e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
LOHBLHCF_03804 2e-183 lacR K Transcriptional regulator
LOHBLHCF_03805 2.3e-112 yvfI K COG2186 Transcriptional regulators
LOHBLHCF_03806 2.4e-306 yvfH C L-lactate permease
LOHBLHCF_03807 1.2e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LOHBLHCF_03808 1e-31 yvfG S YvfG protein
LOHBLHCF_03809 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
LOHBLHCF_03810 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LOHBLHCF_03811 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
LOHBLHCF_03812 1.2e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LOHBLHCF_03813 8.3e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOHBLHCF_03814 1e-190 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
LOHBLHCF_03815 1.2e-202 epsI GM pyruvyl transferase
LOHBLHCF_03816 2e-194 epsH GT2 S Glycosyltransferase like family 2
LOHBLHCF_03817 1.8e-206 epsG S EpsG family
LOHBLHCF_03818 8.4e-218 epsF GT4 M Glycosyl transferases group 1
LOHBLHCF_03819 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOHBLHCF_03820 3.8e-223 epsD GT4 M Glycosyl transferase 4-like
LOHBLHCF_03821 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
LOHBLHCF_03822 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
LOHBLHCF_03823 4e-122 ywqC M biosynthesis protein
LOHBLHCF_03824 6.3e-76 slr K transcriptional
LOHBLHCF_03825 2.4e-286 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
LOHBLHCF_03827 5.1e-92 padC Q Phenolic acid decarboxylase
LOHBLHCF_03828 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
LOHBLHCF_03829 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LOHBLHCF_03830 9.3e-261 pbpE V Beta-lactamase
LOHBLHCF_03831 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
LOHBLHCF_03832 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
LOHBLHCF_03833 1.8e-295 yveA E amino acid
LOHBLHCF_03834 7.4e-106 yvdT K Transcriptional regulator
LOHBLHCF_03835 4.3e-50 ykkC P Small Multidrug Resistance protein
LOHBLHCF_03836 4.1e-50 sugE P Small Multidrug Resistance protein
LOHBLHCF_03837 5.4e-92 yvdQ S Protein of unknown function (DUF3231)
LOHBLHCF_03839 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LOHBLHCF_03840 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
LOHBLHCF_03841 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
LOHBLHCF_03842 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
LOHBLHCF_03843 5e-154 malA S Protein of unknown function (DUF1189)
LOHBLHCF_03844 8.6e-148 malD P transport
LOHBLHCF_03845 5e-243 malC P COG1175 ABC-type sugar transport systems, permease components
LOHBLHCF_03846 6.9e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
LOHBLHCF_03847 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
LOHBLHCF_03848 1.1e-172 yvdE K Transcriptional regulator
LOHBLHCF_03849 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
LOHBLHCF_03850 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
LOHBLHCF_03851 8.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
LOHBLHCF_03852 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LOHBLHCF_03853 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOHBLHCF_03854 0.0 yxdM V ABC transporter (permease)
LOHBLHCF_03855 5.6e-141 yvcR V ABC transporter, ATP-binding protein
LOHBLHCF_03856 3.2e-195 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LOHBLHCF_03857 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_03858 9.7e-32
LOHBLHCF_03859 9.5e-146 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
LOHBLHCF_03860 1.6e-36 crh G Phosphocarrier protein Chr
LOHBLHCF_03861 1.4e-170 whiA K May be required for sporulation
LOHBLHCF_03862 1.4e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LOHBLHCF_03863 1.7e-165 rapZ S Displays ATPase and GTPase activities
LOHBLHCF_03864 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LOHBLHCF_03865 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LOHBLHCF_03866 2.3e-97 usp CBM50 M protein conserved in bacteria
LOHBLHCF_03867 7.6e-277 S COG0457 FOG TPR repeat
LOHBLHCF_03868 0.0 msbA2 3.6.3.44 V ABC transporter
LOHBLHCF_03870 5e-252
LOHBLHCF_03871 1.1e-69
LOHBLHCF_03872 1.4e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
LOHBLHCF_03873 3.4e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LOHBLHCF_03874 3.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LOHBLHCF_03875 2.8e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LOHBLHCF_03876 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LOHBLHCF_03877 1.7e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LOHBLHCF_03878 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LOHBLHCF_03879 1.2e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LOHBLHCF_03880 1e-139 yvpB NU protein conserved in bacteria
LOHBLHCF_03881 1.3e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
LOHBLHCF_03882 9.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
LOHBLHCF_03883 4.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LOHBLHCF_03884 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
LOHBLHCF_03885 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LOHBLHCF_03886 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LOHBLHCF_03887 1.5e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LOHBLHCF_03888 1.2e-126 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LOHBLHCF_03889 1.8e-133 yvoA K transcriptional
LOHBLHCF_03890 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
LOHBLHCF_03891 1.2e-50 yvlD S Membrane
LOHBLHCF_03892 2.6e-26 pspB KT PspC domain
LOHBLHCF_03893 1.2e-165 yvlB S Putative adhesin
LOHBLHCF_03894 1.8e-48 yvlA
LOHBLHCF_03895 5.7e-33 yvkN
LOHBLHCF_03896 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LOHBLHCF_03897 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LOHBLHCF_03898 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LOHBLHCF_03899 1.2e-30 csbA S protein conserved in bacteria
LOHBLHCF_03900 0.0 yvkC 2.7.9.2 GT Phosphotransferase
LOHBLHCF_03901 7e-101 yvkB K Transcriptional regulator
LOHBLHCF_03902 2.8e-225 yvkA EGP Major facilitator Superfamily
LOHBLHCF_03903 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOHBLHCF_03904 5.3e-56 swrA S Swarming motility protein
LOHBLHCF_03905 5.8e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
LOHBLHCF_03906 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LOHBLHCF_03907 1.6e-123 ftsE D cell division ATP-binding protein FtsE
LOHBLHCF_03908 3.8e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
LOHBLHCF_03909 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
LOHBLHCF_03910 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LOHBLHCF_03911 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LOHBLHCF_03912 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LOHBLHCF_03913 1.8e-65
LOHBLHCF_03914 1.9e-08 fliT S bacterial-type flagellum organization
LOHBLHCF_03915 2.9e-69 fliS N flagellar protein FliS
LOHBLHCF_03916 5.3e-249 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LOHBLHCF_03917 6.1e-57 flaG N flagellar protein FlaG
LOHBLHCF_03918 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LOHBLHCF_03919 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LOHBLHCF_03920 6.1e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LOHBLHCF_03921 5.7e-50 yviE
LOHBLHCF_03922 7.8e-155 flgL N Belongs to the bacterial flagellin family
LOHBLHCF_03923 1.2e-264 flgK N flagellar hook-associated protein
LOHBLHCF_03924 9.2e-78 flgN NOU FlgN protein
LOHBLHCF_03925 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
LOHBLHCF_03926 7e-74 yvyF S flagellar protein
LOHBLHCF_03927 4.7e-126 comFC S Phosphoribosyl transferase domain
LOHBLHCF_03928 3.7e-45 comFB S Late competence development protein ComFB
LOHBLHCF_03929 7.6e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LOHBLHCF_03930 2.1e-154 degV S protein conserved in bacteria
LOHBLHCF_03931 5.8e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOHBLHCF_03932 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LOHBLHCF_03933 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LOHBLHCF_03934 6e-163 yvhJ K Transcriptional regulator
LOHBLHCF_03935 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LOHBLHCF_03936 6.2e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
LOHBLHCF_03937 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
LOHBLHCF_03938 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
LOHBLHCF_03939 3.7e-263 tuaE M Teichuronic acid biosynthesis protein
LOHBLHCF_03940 1.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOHBLHCF_03941 2e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
LOHBLHCF_03942 5.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOHBLHCF_03943 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LOHBLHCF_03944 1.4e-151 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOHBLHCF_03945 2.8e-48 lytB 3.5.1.28 D Stage II sporulation protein
LOHBLHCF_03946 7.3e-36
LOHBLHCF_03947 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LOHBLHCF_03948 2.2e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LOHBLHCF_03950 5.3e-119 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
LOHBLHCF_03951 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LOHBLHCF_03952 2.9e-269 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LOHBLHCF_03953 2.7e-133 tagG GM Transport permease protein
LOHBLHCF_03954 1.1e-52 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
LOHBLHCF_03955 5.4e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LOHBLHCF_03956 9.2e-96 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LOHBLHCF_03957 2e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
LOHBLHCF_03958 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
LOHBLHCF_03959 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LOHBLHCF_03960 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LOHBLHCF_03961 5.6e-54 3.4.11.5 S alpha beta
LOHBLHCF_03962 3.5e-129 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LOHBLHCF_03963 3.9e-160 wecC 1.1.1.336 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOHBLHCF_03964 1.8e-126 M DUF based on E. rectale Gene description (DUF3880)
LOHBLHCF_03966 9.5e-159 wbmJ M Glycosyl transferases group 1
LOHBLHCF_03967 2.4e-127 M Glycosyl transferase group 1 protein
LOHBLHCF_03968 4.4e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LOHBLHCF_03969 1.5e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
LOHBLHCF_03970 7.7e-261 gerBA EG Spore germination protein
LOHBLHCF_03971 1.5e-192 gerBB E Spore germination protein
LOHBLHCF_03972 3.2e-206 gerAC S Spore germination protein
LOHBLHCF_03973 1.3e-246 ywtG EGP Major facilitator Superfamily
LOHBLHCF_03974 1.9e-138 ywtF K Transcriptional regulator
LOHBLHCF_03975 2.1e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
LOHBLHCF_03976 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LOHBLHCF_03977 3.6e-21 ywtC
LOHBLHCF_03978 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LOHBLHCF_03979 8.6e-70 pgsC S biosynthesis protein
LOHBLHCF_03980 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
LOHBLHCF_03981 5.5e-178 rbsR K transcriptional
LOHBLHCF_03982 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOHBLHCF_03983 1.1e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LOHBLHCF_03984 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LOHBLHCF_03985 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
LOHBLHCF_03986 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
LOHBLHCF_03987 7.3e-92 batE T Sh3 type 3 domain protein
LOHBLHCF_03988 8e-48 ywsA S Protein of unknown function (DUF3892)
LOHBLHCF_03989 2.4e-95 ywrO S NADPH-quinone reductase (modulator of drug activity B)
LOHBLHCF_03990 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LOHBLHCF_03991 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LOHBLHCF_03992 1.1e-169 alsR K LysR substrate binding domain
LOHBLHCF_03993 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LOHBLHCF_03994 1.1e-124 ywrJ
LOHBLHCF_03995 1.6e-125 cotB
LOHBLHCF_03996 6.2e-207 cotH M Spore Coat
LOHBLHCF_03997 1.3e-12
LOHBLHCF_03998 4.4e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LOHBLHCF_03999 2.5e-53 S Domain of unknown function (DUF4181)
LOHBLHCF_04000 3.9e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LOHBLHCF_04001 8e-82 ywrC K Transcriptional regulator
LOHBLHCF_04002 1.6e-103 ywrB P Chromate transporter
LOHBLHCF_04003 1.3e-88 ywrA P COG2059 Chromate transport protein ChrA
LOHBLHCF_04005 4.3e-132 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LOHBLHCF_04006 1.7e-52 S MORN repeat variant
LOHBLHCF_04007 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
LOHBLHCF_04008 3.9e-38 ywqI S Family of unknown function (DUF5344)
LOHBLHCF_04009 9.7e-23 S Domain of unknown function (DUF5082)
LOHBLHCF_04010 2.4e-152 ywqG S Domain of unknown function (DUF1963)
LOHBLHCF_04011 7.5e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOHBLHCF_04012 2.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
LOHBLHCF_04013 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
LOHBLHCF_04014 2.3e-115 ywqC M biosynthesis protein
LOHBLHCF_04015 1.2e-17
LOHBLHCF_04016 1.4e-308 ywqB S SWIM zinc finger
LOHBLHCF_04017 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LOHBLHCF_04018 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
LOHBLHCF_04019 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
LOHBLHCF_04020 3.7e-57 ssbB L Single-stranded DNA-binding protein
LOHBLHCF_04021 3.8e-66 ywpG
LOHBLHCF_04022 6.9e-66 ywpF S YwpF-like protein
LOHBLHCF_04023 2.6e-49 srtA 3.4.22.70 M Sortase family
LOHBLHCF_04024 1e-39 ywpD T PhoQ Sensor
LOHBLHCF_04025 5.3e-51 ywpD T Histidine kinase
LOHBLHCF_04026 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LOHBLHCF_04027 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LOHBLHCF_04028 8e-199 S aspartate phosphatase
LOHBLHCF_04029 3.7e-140 flhP N flagellar basal body
LOHBLHCF_04030 5.8e-125 flhO N flagellar basal body
LOHBLHCF_04031 3.5e-180 mbl D Rod shape-determining protein
LOHBLHCF_04032 3e-44 spoIIID K Stage III sporulation protein D
LOHBLHCF_04033 2.1e-70 ywoH K COG1846 Transcriptional regulators
LOHBLHCF_04034 2.7e-211 ywoG EGP Major facilitator Superfamily
LOHBLHCF_04035 9.8e-229 ywoF P Right handed beta helix region
LOHBLHCF_04036 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
LOHBLHCF_04037 2.4e-240 ywoD EGP Major facilitator superfamily
LOHBLHCF_04038 2e-103 phzA Q Isochorismatase family
LOHBLHCF_04039 8.3e-76
LOHBLHCF_04040 4.3e-225 amt P Ammonium transporter
LOHBLHCF_04041 1.6e-58 nrgB K Belongs to the P(II) protein family
LOHBLHCF_04042 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
LOHBLHCF_04043 6.6e-72 ywnJ S VanZ like family
LOHBLHCF_04044 6.9e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
LOHBLHCF_04045 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
LOHBLHCF_04046 9.8e-09 ywnC S Family of unknown function (DUF5362)
LOHBLHCF_04047 1.9e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
LOHBLHCF_04048 2.2e-70 ywnF S Family of unknown function (DUF5392)
LOHBLHCF_04049 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOHBLHCF_04050 5e-142 mta K transcriptional
LOHBLHCF_04051 2.6e-59 ywnC S Family of unknown function (DUF5362)
LOHBLHCF_04052 1.3e-111 ywnB S NAD(P)H-binding
LOHBLHCF_04053 1.7e-64 ywnA K Transcriptional regulator
LOHBLHCF_04054 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LOHBLHCF_04055 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LOHBLHCF_04056 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LOHBLHCF_04057 5.8e-17 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
LOHBLHCF_04058 3.8e-11 csbD K CsbD-like
LOHBLHCF_04059 3e-84 ywmF S Peptidase M50
LOHBLHCF_04060 6.1e-104 S response regulator aspartate phosphatase
LOHBLHCF_04061 5e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LOHBLHCF_04062 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LOHBLHCF_04064 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
LOHBLHCF_04065 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
LOHBLHCF_04066 7.8e-175 spoIID D Stage II sporulation protein D
LOHBLHCF_04067 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOHBLHCF_04068 2.4e-133 ywmB S TATA-box binding
LOHBLHCF_04069 1.3e-32 ywzB S membrane
LOHBLHCF_04070 1.8e-86 ywmA
LOHBLHCF_04071 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LOHBLHCF_04072 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LOHBLHCF_04073 2.5e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LOHBLHCF_04074 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LOHBLHCF_04075 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LOHBLHCF_04076 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LOHBLHCF_04077 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LOHBLHCF_04078 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
LOHBLHCF_04079 2.5e-62 atpI S ATP synthase
LOHBLHCF_04080 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LOHBLHCF_04081 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LOHBLHCF_04082 3.6e-94 ywlG S Belongs to the UPF0340 family
LOHBLHCF_04083 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
LOHBLHCF_04084 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOHBLHCF_04085 1.7e-91 mntP P Probably functions as a manganese efflux pump
LOHBLHCF_04086 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LOHBLHCF_04087 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
LOHBLHCF_04088 6.1e-112 spoIIR S stage II sporulation protein R
LOHBLHCF_04089 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
LOHBLHCF_04091 2.5e-158 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LOHBLHCF_04092 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LOHBLHCF_04093 2.6e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOHBLHCF_04094 7.8e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LOHBLHCF_04095 8.6e-160 ywkB S Membrane transport protein
LOHBLHCF_04096 0.0 sfcA 1.1.1.38 C malic enzyme
LOHBLHCF_04097 1.6e-103 tdk 2.7.1.21 F thymidine kinase
LOHBLHCF_04098 1.1e-32 rpmE J Binds the 23S rRNA
LOHBLHCF_04099 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LOHBLHCF_04100 1.1e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
LOHBLHCF_04101 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOHBLHCF_04102 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LOHBLHCF_04103 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
LOHBLHCF_04104 4.2e-62 spo0F T COG0784 FOG CheY-like receiver
LOHBLHCF_04105 1.8e-90 ywjG S Domain of unknown function (DUF2529)
LOHBLHCF_04106 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LOHBLHCF_04107 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LOHBLHCF_04108 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
LOHBLHCF_04109 0.0 fadF C COG0247 Fe-S oxidoreductase
LOHBLHCF_04110 3.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LOHBLHCF_04111 9.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LOHBLHCF_04112 2.7e-42 ywjC
LOHBLHCF_04113 4.5e-94 ywjB H RibD C-terminal domain
LOHBLHCF_04114 0.0 ywjA V ABC transporter
LOHBLHCF_04115 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOHBLHCF_04116 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
LOHBLHCF_04117 3.6e-94 narJ 1.7.5.1 C nitrate reductase
LOHBLHCF_04118 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
LOHBLHCF_04119 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOHBLHCF_04120 2e-85 arfM T cyclic nucleotide binding
LOHBLHCF_04121 1.3e-136 ywiC S YwiC-like protein
LOHBLHCF_04122 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
LOHBLHCF_04123 1e-213 narK P COG2223 Nitrate nitrite transporter
LOHBLHCF_04124 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LOHBLHCF_04125 4.7e-73 ywiB S protein conserved in bacteria
LOHBLHCF_04126 1e-07 S Bacteriocin subtilosin A
LOHBLHCF_04127 4.9e-270 C Fe-S oxidoreductases
LOHBLHCF_04129 3.3e-132 cbiO V ABC transporter
LOHBLHCF_04130 4.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
LOHBLHCF_04131 1.2e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
LOHBLHCF_04132 2.3e-245 L Peptidase, M16
LOHBLHCF_04134 6.2e-244 ywhL CO amine dehydrogenase activity
LOHBLHCF_04135 3e-190 ywhK CO amine dehydrogenase activity
LOHBLHCF_04136 4.4e-78 S aspartate phosphatase
LOHBLHCF_04138 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
LOHBLHCF_04139 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
LOHBLHCF_04140 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LOHBLHCF_04141 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LOHBLHCF_04142 3.6e-49
LOHBLHCF_04143 5.2e-95 ywhD S YwhD family
LOHBLHCF_04144 3.3e-118 ywhC S Peptidase family M50
LOHBLHCF_04145 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LOHBLHCF_04146 3.3e-71 ywhA K Transcriptional regulator
LOHBLHCF_04147 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LOHBLHCF_04149 1.3e-236 mmr U Major Facilitator Superfamily
LOHBLHCF_04150 6.2e-79 yffB K Transcriptional regulator
LOHBLHCF_04151 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
LOHBLHCF_04152 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
LOHBLHCF_04153 3.1e-36 ywzC S Belongs to the UPF0741 family
LOHBLHCF_04154 5.1e-110 rsfA_1
LOHBLHCF_04155 3.5e-155 ywfM EG EamA-like transporter family
LOHBLHCF_04156 2.1e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LOHBLHCF_04157 1.1e-156 cysL K Transcriptional regulator
LOHBLHCF_04158 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
LOHBLHCF_04159 1.1e-146 ywfI C May function as heme-dependent peroxidase
LOHBLHCF_04160 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
LOHBLHCF_04161 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
LOHBLHCF_04162 1.9e-209 bacE EGP Major facilitator Superfamily
LOHBLHCF_04163 4.7e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LOHBLHCF_04164 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOHBLHCF_04165 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LOHBLHCF_04166 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LOHBLHCF_04167 6e-206 ywfA EGP Major facilitator Superfamily
LOHBLHCF_04168 1.3e-260 lysP E amino acid
LOHBLHCF_04169 0.0 rocB E arginine degradation protein
LOHBLHCF_04170 3.5e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LOHBLHCF_04171 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LOHBLHCF_04172 9.8e-77
LOHBLHCF_04173 6.7e-86 spsL 5.1.3.13 M Spore Coat
LOHBLHCF_04174 3.5e-157 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LOHBLHCF_04175 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LOHBLHCF_04176 4.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LOHBLHCF_04177 1.6e-188 spsG M Spore Coat
LOHBLHCF_04178 3.5e-129 spsF M Spore Coat
LOHBLHCF_04179 1.6e-213 spsE 2.5.1.56 M acid synthase
LOHBLHCF_04180 8.9e-164 spsD 2.3.1.210 K Spore Coat
LOHBLHCF_04181 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
LOHBLHCF_04182 1e-267 spsB M Capsule polysaccharide biosynthesis protein
LOHBLHCF_04183 2.4e-144 spsA M Spore Coat
LOHBLHCF_04184 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LOHBLHCF_04185 4.3e-59 ywdK S small membrane protein
LOHBLHCF_04186 3.7e-238 ywdJ F Xanthine uracil
LOHBLHCF_04187 5e-48 ywdI S Family of unknown function (DUF5327)
LOHBLHCF_04188 7.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LOHBLHCF_04189 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LOHBLHCF_04190 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
LOHBLHCF_04192 1.4e-113 ywdD
LOHBLHCF_04193 1.3e-57 pex K Transcriptional regulator PadR-like family
LOHBLHCF_04194 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LOHBLHCF_04195 2e-28 ywdA
LOHBLHCF_04196 1.1e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
LOHBLHCF_04197 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOHBLHCF_04198 1e-139 focA P Formate/nitrite transporter
LOHBLHCF_04199 2e-149 sacT K transcriptional antiterminator
LOHBLHCF_04201 0.0 vpr O Belongs to the peptidase S8 family
LOHBLHCF_04202 8.1e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOHBLHCF_04203 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
LOHBLHCF_04204 2.9e-202 rodA D Belongs to the SEDS family
LOHBLHCF_04205 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
LOHBLHCF_04206 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LOHBLHCF_04207 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LOHBLHCF_04208 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LOHBLHCF_04209 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LOHBLHCF_04210 1.5e-31 ywzA S membrane
LOHBLHCF_04211 1.8e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LOHBLHCF_04212 1.4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LOHBLHCF_04213 9.5e-60 gtcA S GtrA-like protein
LOHBLHCF_04214 1.1e-121 ywcC K transcriptional regulator
LOHBLHCF_04216 9.8e-49 ywcB S Protein of unknown function, DUF485
LOHBLHCF_04217 2e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOHBLHCF_04218 1e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LOHBLHCF_04219 1.4e-223 ywbN P Dyp-type peroxidase family protein
LOHBLHCF_04220 1.6e-184 ycdO P periplasmic lipoprotein involved in iron transport
LOHBLHCF_04221 1.7e-252 P COG0672 High-affinity Fe2 Pb2 permease
LOHBLHCF_04222 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LOHBLHCF_04223 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LOHBLHCF_04224 4.3e-153 ywbI K Transcriptional regulator
LOHBLHCF_04225 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LOHBLHCF_04226 2.3e-111 ywbG M effector of murein hydrolase
LOHBLHCF_04227 3.6e-208 ywbF EGP Major facilitator Superfamily
LOHBLHCF_04228 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
LOHBLHCF_04229 1.3e-221 ywbD 2.1.1.191 J Methyltransferase
LOHBLHCF_04230 4.4e-67 ywbC 4.4.1.5 E glyoxalase
LOHBLHCF_04231 2e-123 ywbB S Protein of unknown function (DUF2711)
LOHBLHCF_04232 1.6e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOHBLHCF_04233 4.3e-275 epr 3.4.21.62 O Belongs to the peptidase S8 family
LOHBLHCF_04234 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOHBLHCF_04235 1.2e-152 sacY K transcriptional antiterminator
LOHBLHCF_04236 7e-169 gspA M General stress
LOHBLHCF_04237 3.3e-124 ywaF S Integral membrane protein
LOHBLHCF_04238 4e-87 ywaE K Transcriptional regulator
LOHBLHCF_04239 1.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LOHBLHCF_04240 4.4e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
LOHBLHCF_04241 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
LOHBLHCF_04242 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LOHBLHCF_04243 1.9e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOHBLHCF_04244 8e-232 dltB M membrane protein involved in D-alanine export
LOHBLHCF_04245 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOHBLHCF_04246 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LOHBLHCF_04247 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_04248 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LOHBLHCF_04249 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LOHBLHCF_04250 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
LOHBLHCF_04251 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOHBLHCF_04252 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
LOHBLHCF_04253 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
LOHBLHCF_04254 1.1e-19 yxzF
LOHBLHCF_04255 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LOHBLHCF_04256 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LOHBLHCF_04257 1.4e-212 yxlH EGP Major facilitator Superfamily
LOHBLHCF_04258 2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LOHBLHCF_04259 1.5e-166 yxlF V ABC transporter, ATP-binding protein
LOHBLHCF_04260 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
LOHBLHCF_04261 1.7e-28
LOHBLHCF_04262 8.1e-46 yxlC S Family of unknown function (DUF5345)
LOHBLHCF_04263 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
LOHBLHCF_04264 3.3e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
LOHBLHCF_04265 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LOHBLHCF_04266 0.0 cydD V ATP-binding protein
LOHBLHCF_04267 3.4e-308 cydD V ATP-binding
LOHBLHCF_04268 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
LOHBLHCF_04269 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
LOHBLHCF_04270 2.1e-228 cimH C COG3493 Na citrate symporter
LOHBLHCF_04271 6.7e-309 3.4.24.84 O Peptidase family M48
LOHBLHCF_04273 7.3e-155 yxkH G Polysaccharide deacetylase
LOHBLHCF_04274 5.9e-205 msmK P Belongs to the ABC transporter superfamily
LOHBLHCF_04275 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
LOHBLHCF_04276 9.7e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOHBLHCF_04277 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOHBLHCF_04278 2.8e-74 yxkC S Domain of unknown function (DUF4352)
LOHBLHCF_04279 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LOHBLHCF_04280 7.7e-77 S Protein of unknown function (DUF1453)
LOHBLHCF_04281 1.6e-190 yxjM T Signal transduction histidine kinase
LOHBLHCF_04282 9.8e-115 K helix_turn_helix, Lux Regulon
LOHBLHCF_04283 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LOHBLHCF_04285 1.6e-85 yxjI S LURP-one-related
LOHBLHCF_04286 5.5e-61 yxjG 2.1.1.14 E Methionine synthase
LOHBLHCF_04287 2.2e-133 yxjG 2.1.1.14 E Methionine synthase
LOHBLHCF_04288 3.7e-218 yxjG 2.1.1.14 E Methionine synthase
LOHBLHCF_04289 6.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LOHBLHCF_04290 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LOHBLHCF_04291 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LOHBLHCF_04292 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
LOHBLHCF_04293 2.3e-156 rlmA 2.1.1.187 Q Methyltransferase domain
LOHBLHCF_04294 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOHBLHCF_04295 1.3e-101 T Domain of unknown function (DUF4163)
LOHBLHCF_04296 3e-47 yxiS
LOHBLHCF_04297 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
LOHBLHCF_04298 6.6e-224 citH C Citrate transporter
LOHBLHCF_04299 1.1e-143 exoK GH16 M licheninase activity
LOHBLHCF_04300 8.3e-151 licT K transcriptional antiterminator
LOHBLHCF_04301 6.8e-111
LOHBLHCF_04302 6.8e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
LOHBLHCF_04303 7.6e-247 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LOHBLHCF_04304 4.3e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
LOHBLHCF_04305 7.8e-55 padR K Transcriptional regulator PadR-like family
LOHBLHCF_04306 6.5e-61 S Protein of unknown function (DUF2812)
LOHBLHCF_04309 4.5e-43 yxiJ S YxiJ-like protein
LOHBLHCF_04312 1.2e-34
LOHBLHCF_04313 1.1e-83 yxiI S Protein of unknown function (DUF2716)
LOHBLHCF_04314 1.5e-136
LOHBLHCF_04315 8.3e-13 yxiG
LOHBLHCF_04316 5.3e-16 yxiG
LOHBLHCF_04317 1.9e-38 S Protein of unknown function (DUF2750)
LOHBLHCF_04318 3.4e-52 yxxG
LOHBLHCF_04319 1.2e-65 yxiG
LOHBLHCF_04320 7.1e-44
LOHBLHCF_04321 3.8e-76
LOHBLHCF_04322 4.7e-94 S Protein of unknown function (DUF4240)
LOHBLHCF_04323 4.5e-141
LOHBLHCF_04325 7e-55
LOHBLHCF_04326 6.1e-80 wapA M COG3209 Rhs family protein
LOHBLHCF_04327 4.1e-14 yxiJ S YxiJ-like protein
LOHBLHCF_04328 0.0 wapA M COG3209 Rhs family protein
LOHBLHCF_04329 6.2e-163 yxxF EG EamA-like transporter family
LOHBLHCF_04330 1.1e-72 yxiE T Belongs to the universal stress protein A family
LOHBLHCF_04331 3.5e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOHBLHCF_04332 2.3e-310 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOHBLHCF_04333 1.9e-44
LOHBLHCF_04334 1.8e-60
LOHBLHCF_04335 3.2e-68
LOHBLHCF_04336 2.7e-70
LOHBLHCF_04337 2.9e-68 S 37-kD nucleoid-associated bacterial protein
LOHBLHCF_04338 5.2e-56
LOHBLHCF_04339 5.7e-217 S nuclease activity
LOHBLHCF_04340 4e-38 yxiC S Family of unknown function (DUF5344)
LOHBLHCF_04341 2.3e-20 S Domain of unknown function (DUF5082)
LOHBLHCF_04342 2.8e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LOHBLHCF_04343 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LOHBLHCF_04344 4.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
LOHBLHCF_04345 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LOHBLHCF_04346 3.5e-233 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
LOHBLHCF_04347 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LOHBLHCF_04348 3.4e-250 lysP E amino acid
LOHBLHCF_04349 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LOHBLHCF_04350 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOHBLHCF_04351 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LOHBLHCF_04352 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LOHBLHCF_04353 2e-152 yxxB S Domain of Unknown Function (DUF1206)
LOHBLHCF_04354 3.5e-197 eutH E Ethanolamine utilisation protein, EutH
LOHBLHCF_04355 9.9e-247 yxeQ S MmgE/PrpD family
LOHBLHCF_04356 2.3e-212 yxeP 3.5.1.47 E hydrolase activity
LOHBLHCF_04357 4.7e-129 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
LOHBLHCF_04358 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
LOHBLHCF_04359 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
LOHBLHCF_04360 1.4e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOHBLHCF_04361 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOHBLHCF_04362 2.2e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LOHBLHCF_04363 9.9e-149 yidA S hydrolases of the HAD superfamily
LOHBLHCF_04366 1.3e-20 yxeE
LOHBLHCF_04368 8.6e-67
LOHBLHCF_04369 4.3e-175 fhuD P ABC transporter
LOHBLHCF_04370 2.2e-57 yxeA S Protein of unknown function (DUF1093)
LOHBLHCF_04371 0.0 yxdM V ABC transporter (permease)
LOHBLHCF_04372 9.4e-141 yxdL V ABC transporter, ATP-binding protein
LOHBLHCF_04373 2e-180 T PhoQ Sensor
LOHBLHCF_04374 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_04375 3.3e-158 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LOHBLHCF_04376 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LOHBLHCF_04377 2.5e-166 iolH G Xylose isomerase-like TIM barrel
LOHBLHCF_04378 3.1e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LOHBLHCF_04379 4.7e-233 iolF EGP Major facilitator Superfamily
LOHBLHCF_04380 1e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LOHBLHCF_04381 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LOHBLHCF_04382 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LOHBLHCF_04383 1.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LOHBLHCF_04384 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOHBLHCF_04385 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
LOHBLHCF_04386 4.1e-175 iolS C Aldo keto reductase
LOHBLHCF_04388 1.9e-47 yxcD S Protein of unknown function (DUF2653)
LOHBLHCF_04389 9.6e-245 csbC EGP Major facilitator Superfamily
LOHBLHCF_04390 0.0 htpG O Molecular chaperone. Has ATPase activity
LOHBLHCF_04392 1.3e-148 IQ Enoyl-(Acyl carrier protein) reductase
LOHBLHCF_04393 8.3e-210 yxbF K Bacterial regulatory proteins, tetR family
LOHBLHCF_04394 3.2e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LOHBLHCF_04395 3.7e-26 yxaI S membrane protein domain
LOHBLHCF_04396 2.7e-59 S Family of unknown function (DUF5391)
LOHBLHCF_04397 1.4e-75 yxaI S membrane protein domain
LOHBLHCF_04398 1.5e-222 P Protein of unknown function (DUF418)
LOHBLHCF_04399 1.6e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
LOHBLHCF_04400 2.1e-100 yxaF K Transcriptional regulator
LOHBLHCF_04401 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOHBLHCF_04402 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
LOHBLHCF_04403 6.2e-48 S LrgA family
LOHBLHCF_04404 5e-117 yxaC M effector of murein hydrolase
LOHBLHCF_04405 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
LOHBLHCF_04406 8e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LOHBLHCF_04407 2.8e-126 gntR K transcriptional
LOHBLHCF_04408 8.6e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
LOHBLHCF_04409 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
LOHBLHCF_04410 8.5e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LOHBLHCF_04411 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
LOHBLHCF_04412 1.9e-286 ahpF O Alkyl hydroperoxide reductase
LOHBLHCF_04413 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOHBLHCF_04414 5.3e-31 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
LOHBLHCF_04415 3.8e-128 yydK K Transcriptional regulator
LOHBLHCF_04416 9.5e-119 S ABC-2 family transporter protein
LOHBLHCF_04417 1.6e-109 prrC P ABC transporter
LOHBLHCF_04418 4.2e-133 yydH O Peptidase M50
LOHBLHCF_04419 1e-184 S Radical SAM superfamily
LOHBLHCF_04420 2.3e-11
LOHBLHCF_04421 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
LOHBLHCF_04422 5.4e-18
LOHBLHCF_04423 3.2e-105 mjecl24 D Involved in chromosome partitioning
LOHBLHCF_04424 1.4e-11
LOHBLHCF_04425 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LOHBLHCF_04426 1.1e-09 S YyzF-like protein
LOHBLHCF_04427 1.3e-67
LOHBLHCF_04428 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LOHBLHCF_04430 1.7e-30 yycQ S Protein of unknown function (DUF2651)
LOHBLHCF_04431 5.4e-201 yycP
LOHBLHCF_04432 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LOHBLHCF_04433 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
LOHBLHCF_04434 1.2e-186 S aspartate phosphatase
LOHBLHCF_04436 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
LOHBLHCF_04437 1.3e-260 rocE E amino acid
LOHBLHCF_04438 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LOHBLHCF_04439 7.4e-16
LOHBLHCF_04440 2.8e-94
LOHBLHCF_04441 2.3e-24 S Sporulation delaying protein SdpA
LOHBLHCF_04442 1.1e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LOHBLHCF_04443 1.5e-40 sdpR K transcriptional
LOHBLHCF_04444 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LOHBLHCF_04445 2.7e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOHBLHCF_04446 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LOHBLHCF_04447 1.2e-154 yycI S protein conserved in bacteria
LOHBLHCF_04448 2e-258 yycH S protein conserved in bacteria
LOHBLHCF_04449 0.0 vicK 2.7.13.3 T Histidine kinase
LOHBLHCF_04450 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOHBLHCF_04455 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LOHBLHCF_04456 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOHBLHCF_04457 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LOHBLHCF_04458 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
LOHBLHCF_04460 1.9e-15 yycC K YycC-like protein
LOHBLHCF_04461 8.4e-221 yeaN P COG2807 Cyanate permease
LOHBLHCF_04462 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LOHBLHCF_04463 2.2e-73 rplI J binds to the 23S rRNA
LOHBLHCF_04464 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LOHBLHCF_04465 8.3e-160 yybS S membrane
LOHBLHCF_04467 3.9e-84 cotF M Spore coat protein
LOHBLHCF_04468 3.4e-67 ydeP3 K Transcriptional regulator
LOHBLHCF_04469 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LOHBLHCF_04470 1.3e-70
LOHBLHCF_04472 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
LOHBLHCF_04473 4.3e-111 K TipAS antibiotic-recognition domain
LOHBLHCF_04474 2.1e-124
LOHBLHCF_04475 1.5e-65 yybH S SnoaL-like domain
LOHBLHCF_04476 2.1e-122 yybG S Pentapeptide repeat-containing protein
LOHBLHCF_04477 1.1e-217 ynfM EGP Major facilitator Superfamily
LOHBLHCF_04478 6.9e-164 yybE K Transcriptional regulator
LOHBLHCF_04479 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
LOHBLHCF_04480 1.2e-74 yybC
LOHBLHCF_04481 1.4e-124 S Metallo-beta-lactamase superfamily
LOHBLHCF_04482 5.6e-77 yybA 2.3.1.57 K transcriptional
LOHBLHCF_04483 4.5e-71 yjcF S Acetyltransferase (GNAT) domain
LOHBLHCF_04484 5e-97 yyaS S Membrane
LOHBLHCF_04485 1.3e-93 yyaR K Acetyltransferase (GNAT) domain
LOHBLHCF_04486 3.5e-66 yyaQ S YjbR
LOHBLHCF_04487 3.8e-107 yyaP 1.5.1.3 H RibD C-terminal domain
LOHBLHCF_04488 9.5e-245 tetL EGP Major facilitator Superfamily
LOHBLHCF_04489 1.7e-26 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LOHBLHCF_04490 2.1e-23 yyaR K acetyltransferase
LOHBLHCF_04492 3.8e-53 L Recombinase
LOHBLHCF_04494 7.8e-61
LOHBLHCF_04496 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LOHBLHCF_04497 2.2e-165 yyaK S CAAX protease self-immunity
LOHBLHCF_04498 1.4e-243 EGP Major facilitator superfamily
LOHBLHCF_04499 7.6e-92 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
LOHBLHCF_04500 2.6e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOHBLHCF_04501 6.8e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
LOHBLHCF_04502 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
LOHBLHCF_04503 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LOHBLHCF_04504 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LOHBLHCF_04505 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
LOHBLHCF_04506 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LOHBLHCF_04507 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOHBLHCF_04508 2.3e-33 yyzM S protein conserved in bacteria
LOHBLHCF_04509 8.1e-177 yyaD S Membrane
LOHBLHCF_04510 2.8e-111 yyaC S Sporulation protein YyaC
LOHBLHCF_04511 6e-149 spo0J K Belongs to the ParB family
LOHBLHCF_04512 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
LOHBLHCF_04513 5.7e-74 S Bacterial PH domain
LOHBLHCF_04514 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LOHBLHCF_04515 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LOHBLHCF_04516 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LOHBLHCF_04517 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LOHBLHCF_04518 6.5e-108 jag S single-stranded nucleic acid binding R3H
LOHBLHCF_04519 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LOHBLHCF_04520 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LOHBLHCF_04532 5.3e-87 S response regulator aspartate phosphatase
LOHBLHCF_04533 9.5e-25 S Mitochondrial biogenesis AIM24
LOHBLHCF_04536 1e-13
LOHBLHCF_04539 2.4e-19 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
LOHBLHCF_04540 1.1e-14 V VanZ like family
LOHBLHCF_04542 6.2e-12
LOHBLHCF_04543 1.5e-25 yvrI K COG1191 DNA-directed RNA polymerase specialized sigma subunit
LOHBLHCF_04544 2.1e-09 S YvrJ protein family
LOHBLHCF_04545 6.2e-46
LOHBLHCF_04547 1.6e-07 O Glutaredoxin
LOHBLHCF_04549 1.7e-26
LOHBLHCF_04552 3e-119 L Belongs to the 'phage' integrase family
LOHBLHCF_04553 2.4e-67
LOHBLHCF_04555 2.3e-131 V HNH endonuclease
LOHBLHCF_04558 4.5e-25 V HNH endonuclease
LOHBLHCF_04559 3.4e-16 V HNH endonuclease
LOHBLHCF_04560 2.8e-15 S Bacterial PH domain
LOHBLHCF_04561 1.4e-44 ydbT S Bacterial PH domain
LOHBLHCF_04563 8.7e-09
LOHBLHCF_04565 1.9e-25 S Repressor of ComK
LOHBLHCF_04566 1.1e-17 abrB K SpoVT / AbrB like domain
LOHBLHCF_04571 6.6e-13 sftA D Belongs to the FtsK SpoIIIE SftA family
LOHBLHCF_04573 4.7e-13 S Protein of unknown function (DUF1064)
LOHBLHCF_04578 1.9e-10 S helicase activity
LOHBLHCF_04583 1.2e-238 L COG3328 Transposase and inactivated derivatives
LOHBLHCF_04589 8.6e-41 nucA M Deoxyribonuclease NucA/NucB
LOHBLHCF_04590 4.2e-149 L TIGRFAM Transposase, IS605 OrfB, C-terminal
LOHBLHCF_04591 2.8e-42 L Transposase IS200 like
LOHBLHCF_04595 1e-135 S response regulator aspartate phosphatase
LOHBLHCF_04597 1.4e-35 radC L RadC-like JAB domain
LOHBLHCF_04598 4.4e-26
LOHBLHCF_04600 9.8e-18 S YolD-like protein
LOHBLHCF_04602 4.1e-08 3.2.1.80, 3.4.24.40 L Protein of unknown function (DUF3991)
LOHBLHCF_04607 1.8e-149 M Psort location Cellwall, score
LOHBLHCF_04608 4.6e-54 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LOHBLHCF_04609 3.9e-13 S mRNA catabolic process
LOHBLHCF_04611 2.5e-08 ssb L single-stranded DNA binding
LOHBLHCF_04612 1.9e-07 ropB K Helix-turn-helix domain
LOHBLHCF_04620 3.4e-50 ypuA S Protein of unknown function (DUF1002)
LOHBLHCF_04622 1.1e-08 S CAAX protease self-immunity
LOHBLHCF_04623 1.7e-32 L DnaD domain protein
LOHBLHCF_04624 2.1e-162 L TIGRFAM Transposase, IS605 OrfB, C-terminal
LOHBLHCF_04625 1.4e-20 K Transcriptional regulator
LOHBLHCF_04631 1.1e-07
LOHBLHCF_04637 6.2e-32 pilT NU Tfp pilus assembly protein pilus retraction ATPase PilT
LOHBLHCF_04640 3.4e-10 yddH M NlpC P60 family protein
LOHBLHCF_04644 1.8e-16 K sigma factor activity
LOHBLHCF_04651 7.3e-48 repB L Initiator Replication protein
LOHBLHCF_04652 4.1e-27
LOHBLHCF_04653 3.3e-159 S Domain of unknown function (DUF5068)
LOHBLHCF_04654 9.8e-14 K Transcriptional regulator
LOHBLHCF_04655 3.2e-09 K Transcriptional regulator
LOHBLHCF_04661 8.9e-61
LOHBLHCF_04662 5.8e-13
LOHBLHCF_04670 1.2e-11 K Helix-turn-helix XRE-family like proteins
LOHBLHCF_04673 4.4e-11 lexA 3.4.21.88 KT domain protein
LOHBLHCF_04674 2.5e-09 K Transcriptional regulator
LOHBLHCF_04678 3.5e-17 coiA 3.6.4.12 S Competence protein CoiA-like family
LOHBLHCF_04680 2.5e-60 L Transposase IS200 like
LOHBLHCF_04681 1.1e-163 L TIGRFAM Transposase, IS605 OrfB, C-terminal
LOHBLHCF_04690 1.4e-43 yoaW
LOHBLHCF_04700 1.6e-66 V ABC transporter
LOHBLHCF_04701 2.8e-81
LOHBLHCF_04704 5.9e-120 S SMART Tetratricopeptide domain protein
LOHBLHCF_04707 4.1e-25 abrB K Transition state
LOHBLHCF_04709 1.4e-10 yddI
LOHBLHCF_04710 2e-74 yddH CBM50 M Lysozyme-like
LOHBLHCF_04713 1.2e-35 M Psort location CytoplasmicMembrane, score
LOHBLHCF_04715 6e-117 yddE S AAA-like domain
LOHBLHCF_04719 5.6e-22 yddB S Conjugative transposon protein TcpC
LOHBLHCF_04720 3.9e-50 U TraM recognition site of TraD and TraG
LOHBLHCF_04723 5.3e-127
LOHBLHCF_04724 2.8e-07
LOHBLHCF_04726 1.6e-21
LOHBLHCF_04727 1.8e-25
LOHBLHCF_04730 5.2e-79 S SprT-like family
LOHBLHCF_04731 8.2e-43 3.1.31.1 L Staphylococcal nuclease homologues
LOHBLHCF_04735 5.3e-34 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LOHBLHCF_04738 1.7e-21
LOHBLHCF_04739 7.4e-155 pre D plasmid recombination enzyme
LOHBLHCF_04740 1.2e-69 K Transcriptional regulator
LOHBLHCF_04742 6e-104 S Tetratricopeptide repeat
LOHBLHCF_04743 1.8e-179 L Replication protein
LOHBLHCF_04744 7.2e-21
LOHBLHCF_04747 3.5e-76 O Hsp20/alpha crystallin family
LOHBLHCF_04748 1.2e-216 pre D plasmid recombination enzyme
LOHBLHCF_04749 3e-68 K Transcriptional regulator
LOHBLHCF_04751 2.7e-180 L Replication protein
LOHBLHCF_04752 7.6e-85 L resolvase
LOHBLHCF_04753 5.5e-15 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LOHBLHCF_04754 6.5e-11 L Replication initiation factor

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)