ORF_ID e_value Gene_name EC_number CAZy COGs Description
KHCPIEKB_00001 2.5e-139 potB E Binding-protein-dependent transport system inner membrane component
KHCPIEKB_00002 3.9e-126 potC3 E Binding-protein-dependent transport system inner membrane component
KHCPIEKB_00003 1.4e-51 potD2 P ABC transporter
KHCPIEKB_00004 0.0 ade 3.5.4.2 F Adenine deaminase C-terminal domain
KHCPIEKB_00005 2.3e-193 tcsA S ABC transporter substrate-binding protein PnrA-like
KHCPIEKB_00006 2.1e-285 xylG 3.6.3.17 S ABC transporter
KHCPIEKB_00007 1.8e-204 yufP S Belongs to the binding-protein-dependent transport system permease family
KHCPIEKB_00008 3.7e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KHCPIEKB_00009 2.5e-21 EGP Major facilitator Superfamily
KHCPIEKB_00010 2.4e-158 yeaE S Aldo/keto reductase family
KHCPIEKB_00011 1.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHCPIEKB_00013 1.2e-13 L PFAM Integrase catalytic region
KHCPIEKB_00015 4.5e-166 3.2.1.17 M peptidoglycan-binding domain-containing protein
KHCPIEKB_00016 5.8e-39
KHCPIEKB_00017 5.8e-123 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KHCPIEKB_00018 2.2e-128 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KHCPIEKB_00019 7e-270 glnP P ABC transporter
KHCPIEKB_00020 1.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHCPIEKB_00021 3.7e-230 pbuG S permease
KHCPIEKB_00022 1.8e-284 clcA P chloride
KHCPIEKB_00023 1.7e-81 XK27_08850 S Aminoacyl-tRNA editing domain
KHCPIEKB_00024 5.4e-104
KHCPIEKB_00025 1.2e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHCPIEKB_00026 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHCPIEKB_00027 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KHCPIEKB_00028 1.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHCPIEKB_00029 6.8e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHCPIEKB_00030 1.4e-62 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KHCPIEKB_00031 3e-243 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHCPIEKB_00032 1.4e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHCPIEKB_00033 2.2e-37 yaaA S S4 domain protein YaaA
KHCPIEKB_00034 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHCPIEKB_00035 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHCPIEKB_00036 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHCPIEKB_00037 5.1e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KHCPIEKB_00038 1.4e-88 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KHCPIEKB_00039 3.3e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHCPIEKB_00040 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KHCPIEKB_00041 4e-75 rplI J Binds to the 23S rRNA
KHCPIEKB_00042 6.8e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KHCPIEKB_00043 1.2e-227 MA20_36090 S Protein of unknown function (DUF2974)
KHCPIEKB_00044 0.0 V ATPases associated with a variety of cellular activities
KHCPIEKB_00045 1.1e-68
KHCPIEKB_00047 1.5e-121 yhiD S MgtC family
KHCPIEKB_00048 9.7e-115 dnaD L DnaD domain protein
KHCPIEKB_00049 7.2e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHCPIEKB_00050 6.8e-150 S Sucrose-6F-phosphate phosphohydrolase
KHCPIEKB_00051 2.1e-70 I Psort location Cytoplasmic, score
KHCPIEKB_00052 5.6e-58 I acetylesterase activity
KHCPIEKB_00053 2.4e-189 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCPIEKB_00054 0.0 dap2 3.4.19.1 E Prolyl oligopeptidase family
KHCPIEKB_00055 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KHCPIEKB_00056 2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KHCPIEKB_00057 3.2e-106 ypsA S Belongs to the UPF0398 family
KHCPIEKB_00058 1e-57 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KHCPIEKB_00059 1.5e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KHCPIEKB_00060 1.7e-105 XK27_01810 S Calcineurin-like phosphoesterase
KHCPIEKB_00061 4.4e-67 XK27_01810 S Calcineurin-like phosphoesterase
KHCPIEKB_00062 5.4e-59
KHCPIEKB_00063 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KHCPIEKB_00064 9.3e-72 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHCPIEKB_00065 1e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHCPIEKB_00066 3.3e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHCPIEKB_00067 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
KHCPIEKB_00068 5.6e-43 gcvR T Belongs to the UPF0237 family
KHCPIEKB_00069 2.9e-246 XK27_08635 S UPF0210 protein
KHCPIEKB_00070 3.7e-307 FbpA K Fibronectin-binding protein
KHCPIEKB_00071 6.3e-157 degV S EDD domain protein, DegV family
KHCPIEKB_00072 3.6e-183
KHCPIEKB_00073 1.3e-165 EG EamA-like transporter family
KHCPIEKB_00074 2.1e-120 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCPIEKB_00075 3.3e-86 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCPIEKB_00076 2.5e-112 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHCPIEKB_00077 2.6e-52 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHCPIEKB_00078 1.4e-115 3.1.3.73 G phosphoglycerate mutase
KHCPIEKB_00079 4.7e-13 XK27_06780 V ABC transporter permease
KHCPIEKB_00080 6e-91 C Nitroreductase family
KHCPIEKB_00081 8.8e-61 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KHCPIEKB_00082 5.8e-20 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHCPIEKB_00083 1.3e-144 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHCPIEKB_00084 1.1e-200 xerS L Belongs to the 'phage' integrase family
KHCPIEKB_00085 2.4e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KHCPIEKB_00086 2.9e-194 S Uncharacterized protein conserved in bacteria (DUF2325)
KHCPIEKB_00087 1.8e-72 S Sel1-like repeats.
KHCPIEKB_00088 1.8e-131 T Diguanylate cyclase, GGDEF domain
KHCPIEKB_00089 3.3e-94 GM NmrA-like family
KHCPIEKB_00090 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KHCPIEKB_00091 1.3e-293 hsdM 2.1.1.72 V type I restriction-modification system
KHCPIEKB_00092 3.2e-138 3.1.21.3 V Type I restriction modification DNA specificity domain
KHCPIEKB_00093 3.2e-172 L Belongs to the 'phage' integrase family
KHCPIEKB_00094 2.4e-126 3.1.21.3 V Type I restriction modification DNA specificity domain
KHCPIEKB_00095 3.6e-33 lysR7 K LysR substrate binding domain
KHCPIEKB_00096 4.7e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KHCPIEKB_00097 4.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KHCPIEKB_00098 5.4e-248 EGP Major facilitator Superfamily
KHCPIEKB_00099 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KHCPIEKB_00101 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KHCPIEKB_00102 0.0 S SH3-like domain
KHCPIEKB_00103 1e-234
KHCPIEKB_00104 5.4e-98 P nitrite transmembrane transporter activity
KHCPIEKB_00105 3.5e-53 EGP Major Facilitator Superfamily
KHCPIEKB_00106 1.6e-41 XK27_05520
KHCPIEKB_00107 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHCPIEKB_00108 2.5e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHCPIEKB_00109 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHCPIEKB_00110 1.6e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KHCPIEKB_00111 2.8e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHCPIEKB_00112 5.2e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHCPIEKB_00113 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHCPIEKB_00114 3.8e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHCPIEKB_00115 1e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KHCPIEKB_00116 6.5e-110 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHCPIEKB_00117 4.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KHCPIEKB_00118 3.1e-242 purD 6.3.4.13 F Belongs to the GARS family
KHCPIEKB_00119 1.5e-56 livF E ABC transporter
KHCPIEKB_00120 3.2e-92 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KHCPIEKB_00121 1.3e-65 arsC 1.20.4.1 P Belongs to the ArsC family
KHCPIEKB_00122 9.9e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KHCPIEKB_00123 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KHCPIEKB_00124 5e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KHCPIEKB_00125 2.4e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHCPIEKB_00126 8.1e-73 yqhY S Asp23 family, cell envelope-related function
KHCPIEKB_00127 1.8e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHCPIEKB_00128 4.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHCPIEKB_00129 8e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHCPIEKB_00130 1.7e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHCPIEKB_00131 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KHCPIEKB_00132 7.8e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KHCPIEKB_00133 1.1e-306 recN L May be involved in recombinational repair of damaged DNA
KHCPIEKB_00134 1.6e-46 oppA E transmembrane transport
KHCPIEKB_00135 2.9e-14 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00136 3.2e-33 oppA E transmembrane transport
KHCPIEKB_00137 2.3e-50
KHCPIEKB_00138 1.1e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KHCPIEKB_00139 2.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHCPIEKB_00140 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHCPIEKB_00141 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHCPIEKB_00142 1.4e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHCPIEKB_00143 4.3e-138 stp 3.1.3.16 T phosphatase
KHCPIEKB_00144 0.0 KLT serine threonine protein kinase
KHCPIEKB_00145 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KHCPIEKB_00146 4.7e-128 thiN 2.7.6.2 H thiamine pyrophosphokinase
KHCPIEKB_00147 3.5e-109 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00148 1.7e-108 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00149 1.9e-13 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00150 1e-27
KHCPIEKB_00151 2.5e-129 yliE T Putative diguanylate phosphodiesterase
KHCPIEKB_00154 9.1e-156 pstS P Phosphate
KHCPIEKB_00155 1.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
KHCPIEKB_00156 2.8e-157 pstA P Phosphate transport system permease protein PstA
KHCPIEKB_00157 3.2e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHCPIEKB_00158 1.8e-113 phoU P Plays a role in the regulation of phosphate uptake
KHCPIEKB_00159 1.4e-124 T Transcriptional regulatory protein, C terminal
KHCPIEKB_00160 4.1e-303 phoR 2.7.13.3 T Histidine kinase
KHCPIEKB_00161 2.4e-21 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KHCPIEKB_00162 1.1e-35 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KHCPIEKB_00163 1e-14 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KHCPIEKB_00164 1.3e-84 lsa S ABC transporter
KHCPIEKB_00166 3.2e-121 3.6.1.13 L NUDIX domain
KHCPIEKB_00167 2.3e-46 S Glycosyl hydrolases family 18
KHCPIEKB_00168 7.6e-129 S Glycosyl hydrolases family 18
KHCPIEKB_00169 1.1e-103 I NUDIX domain
KHCPIEKB_00170 1e-11 S C4-dicarboxylate anaerobic carrier
KHCPIEKB_00171 4e-136 S C4-dicarboxylate anaerobic carrier
KHCPIEKB_00172 4.2e-141 cbiO2 P ABC transporter
KHCPIEKB_00173 6.9e-150 P ABC transporter
KHCPIEKB_00174 7.8e-135 cbiQ P Cobalt transport protein
KHCPIEKB_00175 8.4e-103 2.7.7.65 T phosphorelay sensor kinase activity
KHCPIEKB_00177 1.1e-297 yliE T Putative diguanylate phosphodiesterase
KHCPIEKB_00178 1.8e-192 2.7.7.65 T diguanylate cyclase
KHCPIEKB_00179 9e-104
KHCPIEKB_00180 5e-153 supH G Sucrose-6F-phosphate phosphohydrolase
KHCPIEKB_00182 8.3e-48 lmrA V (ABC) transporter
KHCPIEKB_00184 1e-41 V ABC transporter, ATP-binding protein
KHCPIEKB_00185 9.5e-53 V abc transporter atp-binding protein
KHCPIEKB_00186 2.1e-185 yfiC V ABC transporter
KHCPIEKB_00187 7.6e-31 yfiC V ABC transporter
KHCPIEKB_00188 1.3e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHCPIEKB_00189 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHCPIEKB_00190 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHCPIEKB_00191 1.4e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
KHCPIEKB_00192 1.1e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KHCPIEKB_00193 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KHCPIEKB_00194 7.7e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KHCPIEKB_00195 3.7e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
KHCPIEKB_00196 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KHCPIEKB_00197 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KHCPIEKB_00198 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KHCPIEKB_00199 2e-59 ypmB S Protein conserved in bacteria
KHCPIEKB_00200 2.5e-47 EGP Major facilitator Superfamily
KHCPIEKB_00201 7.6e-115 EGP Major facilitator Superfamily
KHCPIEKB_00202 2.9e-35 P nitrite transmembrane transporter activity
KHCPIEKB_00203 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHCPIEKB_00204 3.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KHCPIEKB_00205 2.5e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHCPIEKB_00206 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHCPIEKB_00207 4.4e-247 dnaB L Replication initiation and membrane attachment
KHCPIEKB_00208 1.5e-169 dnaI L Primosomal protein DnaI
KHCPIEKB_00209 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHCPIEKB_00210 2.1e-42
KHCPIEKB_00211 2.3e-32
KHCPIEKB_00212 4.5e-274 S Archaea bacterial proteins of unknown function
KHCPIEKB_00213 5.4e-113 guaB2 L Resolvase, N terminal domain
KHCPIEKB_00214 7.6e-299 L Putative transposase DNA-binding domain
KHCPIEKB_00215 2.6e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHCPIEKB_00216 1.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KHCPIEKB_00217 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHCPIEKB_00218 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
KHCPIEKB_00219 2.9e-119 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHCPIEKB_00220 1.9e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KHCPIEKB_00221 1.2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHCPIEKB_00222 1.9e-214 ylbM S Belongs to the UPF0348 family
KHCPIEKB_00223 8.4e-102 yceD S Uncharacterized ACR, COG1399
KHCPIEKB_00224 2.9e-128 K response regulator
KHCPIEKB_00225 3e-290 arlS 2.7.13.3 T Histidine kinase
KHCPIEKB_00226 4.4e-156 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHCPIEKB_00227 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KHCPIEKB_00228 4e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHCPIEKB_00229 2e-61 yodB K Transcriptional regulator, HxlR family
KHCPIEKB_00230 2.1e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHCPIEKB_00231 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHCPIEKB_00232 5.3e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHCPIEKB_00233 0.0 S membrane
KHCPIEKB_00234 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KHCPIEKB_00235 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KHCPIEKB_00236 2.1e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHCPIEKB_00237 2.2e-117 gluP 3.4.21.105 S Rhomboid family
KHCPIEKB_00238 2.5e-33 yqgQ S Bacterial protein of unknown function (DUF910)
KHCPIEKB_00239 2.6e-70 yqhL P Rhodanese-like protein
KHCPIEKB_00240 5.2e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHCPIEKB_00241 3.6e-108 ynbB 4.4.1.1 P aluminum resistance
KHCPIEKB_00242 9.7e-79 ynbB 4.4.1.1 P aluminum resistance
KHCPIEKB_00243 2.8e-257 glnA 6.3.1.2 E glutamine synthetase
KHCPIEKB_00244 2.3e-218 EGP Major facilitator Superfamily
KHCPIEKB_00245 1.2e-64 S Domain of unknown function DUF1828
KHCPIEKB_00248 2.2e-58 ytrA K helix_turn_helix gluconate operon transcriptional repressor
KHCPIEKB_00249 9.6e-169 ytrB V ABC transporter
KHCPIEKB_00250 0.0 S ABC-type transport system involved in multi-copper enzyme maturation permease component
KHCPIEKB_00251 3e-254 cycA E Amino acid permease
KHCPIEKB_00252 7.6e-160 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
KHCPIEKB_00253 7.6e-100 S UPF0397 protein
KHCPIEKB_00254 0.0 ykoD P ABC transporter, ATP-binding protein
KHCPIEKB_00255 3.3e-144 cbiQ P cobalt transport
KHCPIEKB_00256 1e-262 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
KHCPIEKB_00257 1.4e-84 S ECF-type riboflavin transporter, S component
KHCPIEKB_00258 1.3e-11 5.99.1.2 T diguanylate cyclase
KHCPIEKB_00259 1.8e-110 T EAL domain
KHCPIEKB_00260 3.7e-16 5.99.1.2 T diguanylate cyclase
KHCPIEKB_00261 1.5e-20 5.99.1.2 T diguanylate cyclase
KHCPIEKB_00262 3.4e-73 2.7.13.3 T diguanylate cyclase
KHCPIEKB_00263 4.6e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KHCPIEKB_00264 4.6e-211 EGP Transmembrane secretion effector
KHCPIEKB_00265 8.6e-201
KHCPIEKB_00266 8.5e-159 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHCPIEKB_00267 1.1e-225 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
KHCPIEKB_00268 1.1e-233 6.3.2.4 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHCPIEKB_00269 2.2e-93 3.6.1.13 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KHCPIEKB_00270 2.7e-307 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00271 8.7e-60 yvoA_1 K Transcriptional regulator, GntR family
KHCPIEKB_00272 5.7e-121 skfE V ATPases associated with a variety of cellular activities
KHCPIEKB_00274 1.5e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHCPIEKB_00275 2.5e-181 yeiH S Conserved hypothetical protein 698
KHCPIEKB_00276 3.8e-162 K LysR substrate binding domain
KHCPIEKB_00277 8.5e-107 F NUDIX domain
KHCPIEKB_00278 2.2e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHCPIEKB_00279 9.4e-77 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHCPIEKB_00280 2.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHCPIEKB_00281 2.4e-101 yvrI K sigma factor activity
KHCPIEKB_00282 1.8e-33
KHCPIEKB_00283 2.7e-73 4.2.99.20 S Alpha/beta hydrolase family
KHCPIEKB_00284 2.8e-32 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHCPIEKB_00285 1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KHCPIEKB_00286 1.8e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHCPIEKB_00287 5.2e-101 nusG K Participates in transcription elongation, termination and antitermination
KHCPIEKB_00288 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHCPIEKB_00289 2e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHCPIEKB_00290 2.9e-190 S Glycosyl transferase family 2
KHCPIEKB_00291 1.6e-230 amtB P ammonium transporter
KHCPIEKB_00292 8.5e-69
KHCPIEKB_00293 2.7e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
KHCPIEKB_00298 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHCPIEKB_00299 7.2e-162 htrA 3.4.21.107 O serine protease
KHCPIEKB_00300 8.8e-150 vicX 3.1.26.11 S domain protein
KHCPIEKB_00301 1.5e-141 yycI S YycH protein
KHCPIEKB_00302 2e-243 yycH S YycH protein
KHCPIEKB_00303 0.0 vicK 2.7.13.3 T Histidine kinase
KHCPIEKB_00304 2.6e-132 K response regulator
KHCPIEKB_00306 2.2e-150 arbV 2.3.1.51 I Acyl-transferase
KHCPIEKB_00307 3.2e-155 arbx M Glycosyl transferase family 8
KHCPIEKB_00308 5.7e-117 arbY M Glycosyl transferase family 8
KHCPIEKB_00309 5.5e-166 arbZ I Phosphate acyltransferases
KHCPIEKB_00310 0.0 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 C FAD binding domain
KHCPIEKB_00311 1.9e-172 K Transcriptional regulator, LysR family
KHCPIEKB_00312 1.6e-85 ydiN C succinate dehydrogenase
KHCPIEKB_00313 7.3e-53 ydiN EGP Major Facilitator Superfamily
KHCPIEKB_00314 2.2e-96 S Membrane
KHCPIEKB_00315 3.5e-222 naiP EGP Major facilitator Superfamily
KHCPIEKB_00316 2.2e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KHCPIEKB_00317 5.6e-172 glk 2.7.1.2 G Glucokinase
KHCPIEKB_00318 1.4e-112 E methionine synthase, vitamin-B12 independent
KHCPIEKB_00319 3.6e-99 2.1.1.14 E methionine synthase, vitamin-B12 independent
KHCPIEKB_00320 6.9e-167 cpsY K Transcriptional regulator, LysR family
KHCPIEKB_00321 1.2e-129
KHCPIEKB_00322 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHCPIEKB_00324 3.6e-208
KHCPIEKB_00325 1.4e-284 V ABC-type multidrug transport system, ATPase and permease components
KHCPIEKB_00326 1e-287 V ABC-type multidrug transport system, ATPase and permease components
KHCPIEKB_00327 1.7e-13 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
KHCPIEKB_00328 4.9e-84 scrB 3.2.1.26 GH32 G invertase
KHCPIEKB_00329 2.7e-51 scrB 3.2.1.26 GH32 G invertase
KHCPIEKB_00330 9.6e-77 2.7.1.199, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHCPIEKB_00331 1.9e-200 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KHCPIEKB_00332 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KHCPIEKB_00333 5e-81 G Belongs to the glycosyl hydrolase 13 family
KHCPIEKB_00334 1.2e-27 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
KHCPIEKB_00335 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KHCPIEKB_00336 2.2e-276 E Amino acid permease
KHCPIEKB_00337 5.9e-80 L Transposase and inactivated derivatives, IS30 family
KHCPIEKB_00338 3.9e-205 G Major Facilitator Superfamily
KHCPIEKB_00339 6.1e-28
KHCPIEKB_00340 1.8e-142 G Major Facilitator Superfamily
KHCPIEKB_00341 2.4e-200 L COG2826 Transposase and inactivated derivatives, IS30 family
KHCPIEKB_00343 3.7e-198 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
KHCPIEKB_00344 2.3e-13 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
KHCPIEKB_00345 1e-221 oxlT P Major Facilitator Superfamily
KHCPIEKB_00347 2.3e-18 K sequence-specific DNA binding
KHCPIEKB_00348 2.4e-47
KHCPIEKB_00349 0.0 recQ1 L Helicase conserved C-terminal domain
KHCPIEKB_00350 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KHCPIEKB_00353 3.1e-109 3.5.2.6 M NlpC/P60 family
KHCPIEKB_00354 9.4e-46 3.5.2.6 M NlpC/P60 family
KHCPIEKB_00355 4.5e-247 cycA E Amino acid permease
KHCPIEKB_00357 8.1e-63 manO S Domain of unknown function (DUF956)
KHCPIEKB_00358 2.4e-167 manN G system, mannose fructose sorbose family IID component
KHCPIEKB_00359 5.4e-139 manY G PTS system
KHCPIEKB_00360 3.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KHCPIEKB_00361 4.1e-71 E Methionine synthase
KHCPIEKB_00362 3.9e-237 EK Aminotransferase, class I
KHCPIEKB_00363 2.2e-168 K LysR substrate binding domain
KHCPIEKB_00364 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KHCPIEKB_00365 1e-76 argR K Regulates arginine biosynthesis genes
KHCPIEKB_00366 3.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHCPIEKB_00367 1.5e-205 S Amidohydrolase
KHCPIEKB_00368 8.5e-176 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCPIEKB_00369 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KHCPIEKB_00370 3.2e-183 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
KHCPIEKB_00371 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHCPIEKB_00372 8.1e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHCPIEKB_00373 0.0 oatA I Acyltransferase
KHCPIEKB_00374 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KHCPIEKB_00375 7.7e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCPIEKB_00376 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KHCPIEKB_00377 5.3e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KHCPIEKB_00378 0.0 L SNF2 family N-terminal domain
KHCPIEKB_00379 1.3e-63
KHCPIEKB_00381 3.2e-98 ywlG S Belongs to the UPF0340 family
KHCPIEKB_00382 1.9e-15 gmuR K UTRA
KHCPIEKB_00383 4.4e-55 gmuR K UbiC transcription regulator-associated domain protein
KHCPIEKB_00384 5.3e-90 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHCPIEKB_00385 6.2e-27
KHCPIEKB_00386 3.5e-206 S Protein of unknown function DUF262
KHCPIEKB_00387 3.6e-58 S Putative inner membrane protein (DUF1819)
KHCPIEKB_00388 5.2e-56 S Domain of unknown function (DUF1788)
KHCPIEKB_00389 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
KHCPIEKB_00390 0.0 V restriction
KHCPIEKB_00391 5.4e-241 S TIGR02687 family
KHCPIEKB_00392 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
KHCPIEKB_00393 7.4e-36 adaA1 2.1.1.63, 3.2.2.21 K PFAM Metal binding domain of Ada
KHCPIEKB_00394 1.3e-54 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHCPIEKB_00395 1.7e-135 S Peptidase family M23
KHCPIEKB_00396 2e-79 mutT 3.6.1.55 F NUDIX domain
KHCPIEKB_00397 1.8e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
KHCPIEKB_00398 4.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHCPIEKB_00399 4.3e-244 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KHCPIEKB_00400 9.8e-23
KHCPIEKB_00401 3.3e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KHCPIEKB_00402 1.5e-160 xerD L Phage integrase, N-terminal SAM-like domain
KHCPIEKB_00403 3.9e-53 S Alpha beta hydrolase
KHCPIEKB_00404 3.8e-21 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KHCPIEKB_00405 1.5e-41 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KHCPIEKB_00406 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KHCPIEKB_00407 8.4e-265 frdC 1.3.5.4 C FAD binding domain
KHCPIEKB_00408 3.4e-113 metI P ABC transporter permease
KHCPIEKB_00409 5.3e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHCPIEKB_00410 3.2e-121 metQ2 P Belongs to the nlpA lipoprotein family
KHCPIEKB_00411 0.0 aha1 P E1-E2 ATPase
KHCPIEKB_00412 1.1e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHCPIEKB_00413 1.8e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHCPIEKB_00414 2.9e-122 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KHCPIEKB_00415 5.4e-65
KHCPIEKB_00416 0.0 E ABC transporter, substratebinding protein
KHCPIEKB_00418 2.8e-125 pnb C nitroreductase
KHCPIEKB_00420 4.9e-159 I Protein of unknown function (DUF2974)
KHCPIEKB_00421 4.3e-101 S Protein of unknown function (DUF2974)
KHCPIEKB_00422 6.3e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
KHCPIEKB_00423 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHCPIEKB_00424 2.1e-212 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHCPIEKB_00425 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHCPIEKB_00426 4.5e-149
KHCPIEKB_00427 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHCPIEKB_00428 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHCPIEKB_00429 1.6e-33 rpsT J Binds directly to 16S ribosomal RNA
KHCPIEKB_00430 1e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
KHCPIEKB_00431 0.0 comEC S Competence protein ComEC
KHCPIEKB_00432 1.1e-69 comEA L Competence protein ComEA
KHCPIEKB_00433 1.3e-179 ylbL T Belongs to the peptidase S16 family
KHCPIEKB_00434 2.6e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHCPIEKB_00435 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KHCPIEKB_00436 1.1e-53 ylbG S UPF0298 protein
KHCPIEKB_00437 2.2e-213 ftsW D Belongs to the SEDS family
KHCPIEKB_00438 0.0 typA T GTP-binding protein TypA
KHCPIEKB_00439 4.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHCPIEKB_00440 2.7e-35 ykzG S Belongs to the UPF0356 family
KHCPIEKB_00441 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHCPIEKB_00442 1.8e-251 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KHCPIEKB_00443 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KHCPIEKB_00444 1e-103 S Repeat protein
KHCPIEKB_00445 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KHCPIEKB_00446 3.5e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KHCPIEKB_00447 3.2e-56 XK27_04120 S Putative amino acid metabolism
KHCPIEKB_00448 2.8e-213 iscS 2.8.1.7 E Aminotransferase class V
KHCPIEKB_00449 3.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHCPIEKB_00450 5.4e-19
KHCPIEKB_00451 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KHCPIEKB_00452 1.5e-32 cspA K 'Cold-shock' DNA-binding domain
KHCPIEKB_00453 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHCPIEKB_00454 9.1e-147 ylmH S S4 domain protein
KHCPIEKB_00455 7.6e-46 yggT S YGGT family
KHCPIEKB_00456 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHCPIEKB_00457 1.4e-219 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHCPIEKB_00458 8.4e-241 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KHCPIEKB_00459 2.3e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KHCPIEKB_00460 1.2e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHCPIEKB_00461 5.6e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHCPIEKB_00462 2.7e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHCPIEKB_00463 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KHCPIEKB_00464 4.8e-55 ftsL D Cell division protein FtsL
KHCPIEKB_00465 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHCPIEKB_00466 4.1e-77 mraZ K Belongs to the MraZ family
KHCPIEKB_00467 5.7e-55 S Protein of unknown function (DUF3397)
KHCPIEKB_00469 1.1e-95 mreD
KHCPIEKB_00470 8.2e-138 mreC M Involved in formation and maintenance of cell shape
KHCPIEKB_00471 2.6e-175 mreB D cell shape determining protein MreB
KHCPIEKB_00472 1.2e-114 radC L DNA repair protein
KHCPIEKB_00473 2.3e-127 S Haloacid dehalogenase-like hydrolase
KHCPIEKB_00474 1.3e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KHCPIEKB_00475 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHCPIEKB_00476 7.8e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KHCPIEKB_00477 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHCPIEKB_00478 1.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
KHCPIEKB_00479 2.9e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KHCPIEKB_00480 1.2e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHCPIEKB_00481 1e-81 yueI S Protein of unknown function (DUF1694)
KHCPIEKB_00482 1.6e-241 rarA L recombination factor protein RarA
KHCPIEKB_00483 1.3e-42
KHCPIEKB_00484 3e-78 usp6 T universal stress protein
KHCPIEKB_00485 2.7e-219 rodA D Belongs to the SEDS family
KHCPIEKB_00486 1.7e-34 S Protein of unknown function (DUF2969)
KHCPIEKB_00487 7.4e-48 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KHCPIEKB_00488 6.1e-177 mbl D Cell shape determining protein MreB Mrl
KHCPIEKB_00489 3.9e-32 ywzB S Protein of unknown function (DUF1146)
KHCPIEKB_00490 4.8e-73 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KHCPIEKB_00491 1.9e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHCPIEKB_00492 2.4e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHCPIEKB_00493 6.5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHCPIEKB_00494 1.8e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHCPIEKB_00495 4.2e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHCPIEKB_00496 3.1e-28 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHCPIEKB_00497 4.2e-127 atpB C it plays a direct role in the translocation of protons across the membrane
KHCPIEKB_00498 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHCPIEKB_00499 9.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KHCPIEKB_00500 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHCPIEKB_00501 2.1e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHCPIEKB_00502 1.4e-112 tdk 2.7.1.21 F thymidine kinase
KHCPIEKB_00503 1.9e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KHCPIEKB_00504 4.3e-34
KHCPIEKB_00505 5.8e-191 ampC V Beta-lactamase
KHCPIEKB_00508 1.2e-177 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00509 6.8e-84 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00510 6.2e-257 pgi 5.3.1.9 G Belongs to the GPI family
KHCPIEKB_00511 3.6e-114 vanZ V VanZ like family
KHCPIEKB_00512 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHCPIEKB_00513 9.1e-276 T PhoQ Sensor
KHCPIEKB_00514 6.1e-134 K Transcriptional regulatory protein, C terminal
KHCPIEKB_00517 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHCPIEKB_00518 1e-184 ytxK 2.1.1.72 L N-6 DNA Methylase
KHCPIEKB_00519 2.5e-10 comGF U Putative Competence protein ComGF
KHCPIEKB_00521 3e-75
KHCPIEKB_00522 6.5e-51 comGC U competence protein ComGC
KHCPIEKB_00523 1.3e-158 comGB NU type II secretion system
KHCPIEKB_00524 4.4e-180 comGA NU Type II IV secretion system protein
KHCPIEKB_00525 7.1e-130 yebC K Transcriptional regulatory protein
KHCPIEKB_00526 7.7e-94 S VanZ like family
KHCPIEKB_00527 1.2e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
KHCPIEKB_00528 8.9e-158 rssA S Phospholipase, patatin family
KHCPIEKB_00529 2.2e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHCPIEKB_00530 0.0 E Amino acid permease
KHCPIEKB_00531 1.7e-63 GM epimerase
KHCPIEKB_00532 6.3e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHCPIEKB_00533 3.1e-66
KHCPIEKB_00534 1.5e-25
KHCPIEKB_00535 1.7e-125 T Diguanylate cyclase, GGDEF domain
KHCPIEKB_00536 5.2e-119 T Diguanylate cyclase, GGDEF domain
KHCPIEKB_00537 1e-181 yliE T Putative diguanylate phosphodiesterase
KHCPIEKB_00538 4.3e-149 T diguanylate cyclase activity
KHCPIEKB_00539 4.4e-138
KHCPIEKB_00540 5e-60 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHCPIEKB_00541 2.5e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHCPIEKB_00542 0.0 copA 3.6.3.54 P P-type ATPase
KHCPIEKB_00543 3.3e-54 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KHCPIEKB_00544 1.4e-77 atkY K Copper transport repressor CopY TcrY
KHCPIEKB_00545 1.1e-56 V peptidase activity
KHCPIEKB_00546 6.8e-150 S hydrolase
KHCPIEKB_00547 5.3e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHCPIEKB_00548 5.5e-167 ybbR S YbbR-like protein
KHCPIEKB_00549 4.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHCPIEKB_00550 2.4e-206 potD P ABC transporter
KHCPIEKB_00551 5e-129 potC P ABC transporter permease
KHCPIEKB_00552 1.1e-144 potB P ABC transporter permease
KHCPIEKB_00553 1.4e-203 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KHCPIEKB_00554 2.9e-162 murB 1.3.1.98 M Cell wall formation
KHCPIEKB_00555 1.2e-97 dnaQ 2.7.7.7 L DNA polymerase III
KHCPIEKB_00556 4.2e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KHCPIEKB_00557 9.7e-183 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KHCPIEKB_00558 2.3e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHCPIEKB_00559 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
KHCPIEKB_00560 5.5e-106
KHCPIEKB_00561 5.4e-46 3.2.2.20 K acetyltransferase
KHCPIEKB_00562 4.4e-27 3.2.2.20 K acetyltransferase
KHCPIEKB_00563 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHCPIEKB_00564 3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KHCPIEKB_00565 2.2e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHCPIEKB_00566 1.8e-212 cggR K Putative sugar-binding domain
KHCPIEKB_00568 5.3e-136 XK27_08845 S ABC transporter, ATP-binding protein
KHCPIEKB_00569 4.5e-50 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KHCPIEKB_00570 2.3e-19 ABC-SBP S ABC transporter substrate binding protein
KHCPIEKB_00571 3.5e-285
KHCPIEKB_00572 5.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHCPIEKB_00573 1.5e-169 whiA K May be required for sporulation
KHCPIEKB_00574 1.4e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KHCPIEKB_00575 2.4e-164 rapZ S Displays ATPase and GTPase activities
KHCPIEKB_00576 2.3e-84 dmpA 3.4.11.19 EQ Peptidase family S58
KHCPIEKB_00578 7.2e-124 E D-aminopeptidase
KHCPIEKB_00579 7.4e-92 S Short repeat of unknown function (DUF308)
KHCPIEKB_00580 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHCPIEKB_00581 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHCPIEKB_00582 8.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHCPIEKB_00583 2.2e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KHCPIEKB_00584 1.5e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHCPIEKB_00585 1.2e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHCPIEKB_00586 9.1e-31
KHCPIEKB_00587 5.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHCPIEKB_00588 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHCPIEKB_00589 1.6e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHCPIEKB_00590 2.3e-122 comFC S Competence protein
KHCPIEKB_00591 2.7e-246 comFA L Helicase C-terminal domain protein
KHCPIEKB_00592 4.7e-117 yvyE 3.4.13.9 S YigZ family
KHCPIEKB_00593 1.1e-212 tagO 2.7.8.33, 2.7.8.35 M transferase
KHCPIEKB_00594 5.1e-221 rny S Endoribonuclease that initiates mRNA decay
KHCPIEKB_00595 4.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHCPIEKB_00596 2.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHCPIEKB_00597 1.7e-106 ymfM S Helix-turn-helix domain
KHCPIEKB_00598 5.2e-133 IQ Enoyl-(Acyl carrier protein) reductase
KHCPIEKB_00599 1.8e-237 S Peptidase M16
KHCPIEKB_00600 4.5e-230 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
KHCPIEKB_00601 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KHCPIEKB_00602 1.9e-68 WQ51_03320 S Protein of unknown function (DUF1149)
KHCPIEKB_00603 8.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHCPIEKB_00604 2.1e-181 yubA S AI-2E family transporter
KHCPIEKB_00605 4.6e-64 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KHCPIEKB_00606 2.9e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KHCPIEKB_00607 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KHCPIEKB_00608 2.8e-22
KHCPIEKB_00609 4e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHCPIEKB_00610 3.9e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHCPIEKB_00611 3.1e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
KHCPIEKB_00612 3.3e-109 yjbK S CYTH
KHCPIEKB_00613 5.9e-112 yjbH Q Thioredoxin
KHCPIEKB_00614 4.4e-163 coiA 3.6.4.12 S Competence protein
KHCPIEKB_00615 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KHCPIEKB_00616 5e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KHCPIEKB_00617 2.1e-302 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHCPIEKB_00618 1.2e-39 ptsH G phosphocarrier protein HPR
KHCPIEKB_00619 5.8e-10
KHCPIEKB_00620 0.0 clpE O Belongs to the ClpA ClpB family
KHCPIEKB_00621 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
KHCPIEKB_00622 4.3e-73 mco Q Multicopper oxidase
KHCPIEKB_00623 7.3e-209 mco Q Multicopper oxidase
KHCPIEKB_00624 5.4e-19
KHCPIEKB_00625 1.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHCPIEKB_00626 1.2e-157 hlyX S Transporter associated domain
KHCPIEKB_00627 3.5e-74
KHCPIEKB_00628 4.5e-85
KHCPIEKB_00629 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
KHCPIEKB_00630 8.1e-244 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHCPIEKB_00631 1.1e-181 D Alpha beta
KHCPIEKB_00632 7.4e-19
KHCPIEKB_00633 4.6e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KHCPIEKB_00634 2e-166 yihY S Belongs to the UPF0761 family
KHCPIEKB_00635 3.6e-162 map 3.4.11.18 E Methionine Aminopeptidase
KHCPIEKB_00636 1.3e-78 fld C Flavodoxin
KHCPIEKB_00637 3.3e-51 gtcA S Teichoic acid glycosylation protein
KHCPIEKB_00638 5e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KHCPIEKB_00639 3.6e-32
KHCPIEKB_00640 8.7e-181 E Amino acid permease
KHCPIEKB_00642 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KHCPIEKB_00643 1.1e-228 ynbB 4.4.1.1 P aluminum resistance
KHCPIEKB_00644 4.6e-233 pyrP F Permease
KHCPIEKB_00645 5e-134 pfoS S Phosphotransferase system, EIIC
KHCPIEKB_00646 8.4e-35 pfoS G Membrane
KHCPIEKB_00648 1.8e-248 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHCPIEKB_00649 2.9e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
KHCPIEKB_00650 1.1e-124 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
KHCPIEKB_00651 1.3e-227 potE E amino acid
KHCPIEKB_00652 9.8e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KHCPIEKB_00653 2.1e-249 yhdP S Transporter associated domain
KHCPIEKB_00654 2.9e-21 3.4.22.70 M Sortase family
KHCPIEKB_00658 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KHCPIEKB_00659 9.1e-130 gntR K UbiC transcription regulator-associated domain protein
KHCPIEKB_00660 1.2e-174 rihB 3.2.2.1 F Nucleoside
KHCPIEKB_00661 5.5e-124 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHCPIEKB_00662 2e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KHCPIEKB_00663 5.7e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHCPIEKB_00664 5.9e-88
KHCPIEKB_00665 6.2e-38
KHCPIEKB_00666 9.1e-79
KHCPIEKB_00667 5.6e-10 S Protein of unknown function (DUF2974)
KHCPIEKB_00668 1e-270 S Uncharacterized protein conserved in bacteria (DUF2252)
KHCPIEKB_00669 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHCPIEKB_00670 2.8e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KHCPIEKB_00671 2e-149 glnH ET Bacterial periplasmic substrate-binding proteins
KHCPIEKB_00672 1.5e-110 glnP P ABC transporter permease
KHCPIEKB_00673 2.5e-110 gluC P ABC transporter permease
KHCPIEKB_00674 6.4e-151 glnH ET ABC transporter substrate-binding protein
KHCPIEKB_00675 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHCPIEKB_00676 3.9e-119 udk 2.7.1.48 F Zeta toxin
KHCPIEKB_00677 3.7e-111 udk 2.7.1.48 F Zeta toxin
KHCPIEKB_00679 1.4e-101 S ABC-type cobalt transport system, permease component
KHCPIEKB_00680 7.8e-210 pepA E M42 glutamyl aminopeptidase
KHCPIEKB_00681 2.2e-281 pipD E Dipeptidase
KHCPIEKB_00682 1.7e-142 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KHCPIEKB_00683 5.5e-119 ybhL S Belongs to the BI1 family
KHCPIEKB_00684 1.9e-217 mdtG EGP Major facilitator Superfamily
KHCPIEKB_00685 2.6e-56
KHCPIEKB_00687 7.2e-50 kgtP EGP Sugar (and other) transporter
KHCPIEKB_00688 9.5e-101 kgtP EGP Sugar (and other) transporter
KHCPIEKB_00689 2.2e-309 ybiT S ABC transporter, ATP-binding protein
KHCPIEKB_00690 2.2e-168 mleP3 S Membrane transport protein
KHCPIEKB_00691 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KHCPIEKB_00692 5.7e-36 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
KHCPIEKB_00693 1.1e-32 mtlD 1.1.1.17 G mannitol metabolic process
KHCPIEKB_00695 4.2e-53 mtlR K transcriptional antiterminator
KHCPIEKB_00696 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHCPIEKB_00697 1.2e-85 K AsnC family
KHCPIEKB_00698 6.4e-52 ypaA S membrane
KHCPIEKB_00699 1.2e-26 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KHCPIEKB_00701 2.9e-27 yliE T Putative diguanylate phosphodiesterase
KHCPIEKB_00702 8.6e-107 T Gaf domain
KHCPIEKB_00703 6.7e-95 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
KHCPIEKB_00704 2.1e-125 alkD L DNA alkylation repair enzyme
KHCPIEKB_00705 1.8e-240 brnQ U Component of the transport system for branched-chain amino acids
KHCPIEKB_00706 1.8e-113 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KHCPIEKB_00707 8.3e-47 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
KHCPIEKB_00708 4.3e-33 copZ P Heavy-metal-associated domain
KHCPIEKB_00709 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
KHCPIEKB_00710 1.8e-20
KHCPIEKB_00711 9.3e-98 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KHCPIEKB_00712 5.8e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
KHCPIEKB_00713 2e-160 L Mrr N-terminal domain
KHCPIEKB_00714 4.8e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHCPIEKB_00715 3e-117 S Protein of unknown function (DUF1211)
KHCPIEKB_00716 1.5e-169 yegS 2.7.1.107 G Lipid kinase
KHCPIEKB_00717 3.2e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHCPIEKB_00718 2.1e-266 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHCPIEKB_00719 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHCPIEKB_00720 3.2e-193 camS S sex pheromone
KHCPIEKB_00721 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHCPIEKB_00722 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KHCPIEKB_00723 1.5e-115 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
KHCPIEKB_00724 4.1e-102 S ECF transporter, substrate-specific component
KHCPIEKB_00726 7.8e-88 ydcK S Belongs to the SprT family
KHCPIEKB_00727 2.1e-111 V ABC transporter
KHCPIEKB_00730 0.0 pacL 3.6.3.8 P P-type ATPase
KHCPIEKB_00731 3.3e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KHCPIEKB_00732 4.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
KHCPIEKB_00733 1e-204 csaB M Glycosyl transferases group 1
KHCPIEKB_00734 1.4e-133 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KHCPIEKB_00735 2.6e-261 epsU S Polysaccharide biosynthesis protein
KHCPIEKB_00736 1.2e-224 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHCPIEKB_00737 3.9e-125 gntR1 K UTRA
KHCPIEKB_00738 9.5e-200
KHCPIEKB_00739 2.9e-215
KHCPIEKB_00740 1.3e-20 oppA2 E ABC transporter substrate-binding protein
KHCPIEKB_00741 8.3e-69 oppA2 E ABC transporter, substratebinding protein
KHCPIEKB_00744 8.8e-166 pfoS S Phosphotransferase system, EIIC
KHCPIEKB_00745 8.5e-226 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KHCPIEKB_00748 2e-91 S Phosphatidylethanolamine-binding protein
KHCPIEKB_00749 9.3e-78 EGP Major facilitator Superfamily
KHCPIEKB_00750 3.3e-76 L Putative transposase DNA-binding domain
KHCPIEKB_00751 3.9e-14 L Putative transposase DNA-binding domain
KHCPIEKB_00752 1.4e-11 L Putative transposase DNA-binding domain
KHCPIEKB_00753 1.3e-121 XK27_07525 3.6.1.55 F NUDIX domain
KHCPIEKB_00754 1.2e-12 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00755 3.4e-68 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00756 1e-139 oppA E ABC transporter, substratebinding protein
KHCPIEKB_00757 1.6e-45
KHCPIEKB_00758 3.9e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
KHCPIEKB_00759 4.2e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHCPIEKB_00760 6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHCPIEKB_00761 2.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHCPIEKB_00762 4.4e-163 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHCPIEKB_00763 7.4e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHCPIEKB_00764 1.3e-61 rplQ J Ribosomal protein L17
KHCPIEKB_00765 5.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHCPIEKB_00766 1.4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHCPIEKB_00767 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHCPIEKB_00768 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHCPIEKB_00769 5.9e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHCPIEKB_00770 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHCPIEKB_00771 1.8e-72 rplO J Binds to the 23S rRNA
KHCPIEKB_00772 1.3e-24 rpmD J Ribosomal protein L30
KHCPIEKB_00773 1.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHCPIEKB_00774 5.7e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHCPIEKB_00775 2.8e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHCPIEKB_00776 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHCPIEKB_00777 9.3e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHCPIEKB_00778 1e-32 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHCPIEKB_00779 1.6e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHCPIEKB_00780 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHCPIEKB_00781 3.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KHCPIEKB_00782 1.9e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHCPIEKB_00783 9.4e-121 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHCPIEKB_00784 8.9e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHCPIEKB_00785 4.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHCPIEKB_00786 2.8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHCPIEKB_00787 8.3e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHCPIEKB_00788 1.6e-106 rplD J Forms part of the polypeptide exit tunnel
KHCPIEKB_00789 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHCPIEKB_00790 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KHCPIEKB_00791 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHCPIEKB_00792 3.5e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHCPIEKB_00793 1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHCPIEKB_00794 9e-08 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KHCPIEKB_00795 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHCPIEKB_00796 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHCPIEKB_00799 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHCPIEKB_00800 2.7e-82 yebR 1.8.4.14 T GAF domain-containing protein
KHCPIEKB_00804 3.7e-108 XK27_00160 S Domain of unknown function (DUF5052)
KHCPIEKB_00805 7.7e-219 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KHCPIEKB_00806 4.1e-22 metY 2.5.1.49 E o-acetylhomoserine
KHCPIEKB_00808 2.1e-91 T diguanylate cyclase activity
KHCPIEKB_00810 2.5e-278 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KHCPIEKB_00811 1.1e-197 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHCPIEKB_00812 5.8e-252 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KHCPIEKB_00813 7.7e-302 E ABC transporter, substratebinding protein
KHCPIEKB_00814 5.3e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHCPIEKB_00815 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHCPIEKB_00816 4.6e-249 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHCPIEKB_00817 7.5e-61 yabR J S1 RNA binding domain
KHCPIEKB_00818 1.5e-59 divIC D Septum formation initiator
KHCPIEKB_00819 3.2e-34 yabO J S4 domain protein
KHCPIEKB_00820 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHCPIEKB_00821 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHCPIEKB_00822 2e-126 S (CBS) domain
KHCPIEKB_00823 5.3e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHCPIEKB_00824 9.4e-71 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHCPIEKB_00825 8.2e-239 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KHCPIEKB_00826 3.6e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHCPIEKB_00827 1.6e-41 rpmE2 J Ribosomal protein L31
KHCPIEKB_00828 7.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHCPIEKB_00829 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHCPIEKB_00830 1.1e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KHCPIEKB_00831 2.5e-65 S Domain of unknown function (DUF1934)
KHCPIEKB_00832 2.8e-254 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHCPIEKB_00833 6.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHCPIEKB_00834 8.9e-43
KHCPIEKB_00835 1.6e-252 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHCPIEKB_00836 4.1e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KHCPIEKB_00837 6.4e-38 veg S Biofilm formation stimulator VEG
KHCPIEKB_00838 1e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHCPIEKB_00839 9.5e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHCPIEKB_00840 1.9e-149 tatD L hydrolase, TatD family
KHCPIEKB_00841 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHCPIEKB_00842 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KHCPIEKB_00843 1.6e-103 S TPM domain
KHCPIEKB_00844 2.3e-89 comEB 3.5.4.12 F MafB19-like deaminase
KHCPIEKB_00845 3.3e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHCPIEKB_00847 1.4e-119
KHCPIEKB_00848 1.4e-27 KLT Protein kinase domain
KHCPIEKB_00849 1.3e-75 KLT Protein kinase domain
KHCPIEKB_00850 1.5e-129 V ATPases associated with a variety of cellular activities
KHCPIEKB_00851 5e-137 V ABC-2 type transporter
KHCPIEKB_00852 2.9e-116 E peptidase
KHCPIEKB_00854 4.1e-41 S Enterocin A Immunity
KHCPIEKB_00855 2.7e-59
KHCPIEKB_00856 1.3e-40 3.4.22.70 M Sortase family
KHCPIEKB_00857 4.2e-97 M ErfK YbiS YcfS YnhG
KHCPIEKB_00858 3.9e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KHCPIEKB_00859 5.3e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHCPIEKB_00860 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KHCPIEKB_00861 8.1e-55 yheA S Belongs to the UPF0342 family
KHCPIEKB_00862 7.8e-227 yhaO L Ser Thr phosphatase family protein
KHCPIEKB_00863 0.0 L AAA domain
KHCPIEKB_00864 1.1e-178 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHCPIEKB_00865 6.6e-68 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F shikimate kinase activity
KHCPIEKB_00866 3.7e-32 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E 3-phosphoshikimate 1-carboxyvinyltransferase activity
KHCPIEKB_00867 3e-154 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHCPIEKB_00868 2.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHCPIEKB_00869 1.2e-132 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KHCPIEKB_00870 2.3e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHCPIEKB_00871 8e-55
KHCPIEKB_00872 3.1e-80 hit FG Scavenger mRNA decapping enzyme C-term binding
KHCPIEKB_00873 9e-136 ecsA V ABC transporter, ATP-binding protein
KHCPIEKB_00874 1.1e-217 ecsB U ABC transporter
KHCPIEKB_00875 5.2e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHCPIEKB_00876 1.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KHCPIEKB_00877 2.6e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHCPIEKB_00878 4.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KHCPIEKB_00879 1.5e-141 K Helix-turn-helix domain
KHCPIEKB_00880 4.3e-34 1.3.5.4 C FAD binding domain
KHCPIEKB_00881 8e-151 yliE T Putative diguanylate phosphodiesterase
KHCPIEKB_00882 1.2e-64 yliE T domain protein
KHCPIEKB_00883 9e-186 arbY M Glycosyl transferase family 8
KHCPIEKB_00884 6.6e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHCPIEKB_00885 3.4e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KHCPIEKB_00886 8.3e-50
KHCPIEKB_00887 1.3e-265 pepC 3.4.22.40 E Peptidase C1-like family
KHCPIEKB_00889 2.4e-183 S AAA domain
KHCPIEKB_00890 2.1e-79 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KHCPIEKB_00891 9.8e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHCPIEKB_00892 5.2e-29
KHCPIEKB_00893 2.6e-28
KHCPIEKB_00894 4.7e-128 pgm3 G Belongs to the phosphoglycerate mutase family
KHCPIEKB_00895 1.5e-50 S membrane transporter protein
KHCPIEKB_00896 3.3e-49 S membrane transporter protein
KHCPIEKB_00897 1e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KHCPIEKB_00898 1.5e-94 wecD K Acetyltransferase (GNAT) family
KHCPIEKB_00899 4.8e-196 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KHCPIEKB_00900 7.3e-103 3.5.2.6 V Beta-lactamase
KHCPIEKB_00901 1.1e-136 ybbH_2 K Helix-turn-helix domain, rpiR family
KHCPIEKB_00902 1.1e-275 pepV 3.5.1.18 E dipeptidase PepV
KHCPIEKB_00903 1.5e-46 cycA E Amino acid permease
KHCPIEKB_00904 3.3e-167 cycA E Amino acid permease
KHCPIEKB_00905 3.4e-08 lacR K DeoR C terminal sensor domain
KHCPIEKB_00906 8e-252 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
KHCPIEKB_00907 6e-147 D nuclear chromosome segregation
KHCPIEKB_00908 4.9e-82 M LysM domain protein
KHCPIEKB_00909 9e-123 G Peptidase_C39 like family
KHCPIEKB_00910 1.8e-121 K 3.5.1.28 M NlpC/P60 family
KHCPIEKB_00911 5.3e-11 M NlpC/P60 family
KHCPIEKB_00912 3.2e-80
KHCPIEKB_00913 9.4e-74 mesH S Teichoic acid glycosylation protein
KHCPIEKB_00914 9.9e-129 S VanZ like family
KHCPIEKB_00915 3.2e-14 sidC L DNA recombination
KHCPIEKB_00916 4.8e-29 sidC L DNA recombination
KHCPIEKB_00917 1.3e-16 sidC L DNA recombination
KHCPIEKB_00918 1.7e-116 L DNA recombination
KHCPIEKB_00919 1.3e-10 sidC L DNA recombination
KHCPIEKB_00920 0.0 3.1.4.46, 3.2.1.99 GH43 N domain, Protein
KHCPIEKB_00922 3.4e-134 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHCPIEKB_00923 4e-124 pgm3 G Phosphoglycerate mutase family
KHCPIEKB_00924 1.2e-112 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KHCPIEKB_00925 0.0 helD 3.6.4.12 L DNA helicase
KHCPIEKB_00926 4.6e-42 glnQ 3.6.3.21 E ABC transporter
KHCPIEKB_00927 5.5e-49 aatB ET ABC transporter substrate-binding protein
KHCPIEKB_00928 1.6e-85 aatB ET ABC transporter substrate-binding protein
KHCPIEKB_00929 1.8e-11 liaI S membrane
KHCPIEKB_00930 2.6e-74 XK27_02470 K LytTr DNA-binding domain
KHCPIEKB_00931 5.7e-103 E GDSL-like Lipase/Acylhydrolase
KHCPIEKB_00932 1e-170 coaA 2.7.1.33 F Pantothenic acid kinase
KHCPIEKB_00933 1.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHCPIEKB_00934 1.6e-76 ymfM S Helix-turn-helix domain
KHCPIEKB_00935 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KHCPIEKB_00936 3e-198
KHCPIEKB_00938 2.9e-218 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
KHCPIEKB_00939 2.2e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
KHCPIEKB_00940 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHCPIEKB_00941 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHCPIEKB_00942 2.9e-29 secG U Preprotein translocase
KHCPIEKB_00943 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KHCPIEKB_00944 6.8e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHCPIEKB_00947 1.9e-215 S FtsX-like permease family
KHCPIEKB_00948 4.9e-117 V ABC transporter, ATP-binding protein
KHCPIEKB_00950 4.8e-21 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
KHCPIEKB_00951 9e-81
KHCPIEKB_00952 1.6e-22 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHCPIEKB_00953 5.3e-37 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHCPIEKB_00954 6e-91 yjcF S Acetyltransferase (GNAT) domain
KHCPIEKB_00955 2.7e-143 sufC O FeS assembly ATPase SufC
KHCPIEKB_00956 5.3e-220 sufD O FeS assembly protein SufD
KHCPIEKB_00957 4.3e-225 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHCPIEKB_00958 4.3e-74 nifU C SUF system FeS assembly protein, NifU family
KHCPIEKB_00959 1.4e-275 sufB O assembly protein SufB
KHCPIEKB_00960 1.2e-72 cydD V abc transporter atp-binding protein
KHCPIEKB_00962 3.1e-90 S biotin transmembrane transporter activity
KHCPIEKB_00963 3.3e-43
KHCPIEKB_00964 3.4e-121
KHCPIEKB_00965 2.4e-12
KHCPIEKB_00966 4.7e-125 gpmB G Phosphoglycerate mutase family
KHCPIEKB_00967 1.2e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KHCPIEKB_00968 7.3e-91 yliE T EAL domain
KHCPIEKB_00969 1.7e-151 yitS S EDD domain protein, DegV family
KHCPIEKB_00970 5.5e-92 racA K Domain of unknown function (DUF1836)
KHCPIEKB_00971 0.0 S Bacterial membrane protein, YfhO
KHCPIEKB_00972 2e-163 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KHCPIEKB_00973 4.2e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHCPIEKB_00974 3.9e-84 K DNA-templated transcription, initiation
KHCPIEKB_00975 7.8e-10
KHCPIEKB_00976 1.1e-138
KHCPIEKB_00977 4.3e-18 yliE T EAL domain
KHCPIEKB_00978 1.2e-29 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KHCPIEKB_00979 1.9e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
KHCPIEKB_00980 3.5e-31 bgl 3.2.1.21, 3.2.1.86 GT1 G beta-glucosidase activity
KHCPIEKB_00982 1.4e-57 C Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
KHCPIEKB_00983 3e-39 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHCPIEKB_00984 9e-184 gpsA 1.1.1.94 I Rossmann-like domain
KHCPIEKB_00985 2.7e-58 K sequence-specific DNA binding
KHCPIEKB_00986 5.4e-91
KHCPIEKB_00987 6.9e-77 F DNA/RNA non-specific endonuclease
KHCPIEKB_00989 8.1e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHCPIEKB_00990 1.6e-132 S Core-2/I-Branching enzyme
KHCPIEKB_00991 2.6e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
KHCPIEKB_00992 7.7e-151 cps1D M Domain of unknown function (DUF4422)
KHCPIEKB_00993 6.6e-220 glf 5.4.99.9 M UDP-galactopyranose mutase
KHCPIEKB_00994 2.4e-172 glfT1 1.1.1.133 S Glycosyltransferase like family 2
KHCPIEKB_00995 1e-183 M Glycosyl transferases group 1
KHCPIEKB_00996 5.1e-198 wbbI M transferase activity, transferring glycosyl groups
KHCPIEKB_00997 8.9e-262 epsIIL S Membrane protein involved in the export of O-antigen and teichoic acid
KHCPIEKB_00998 1.2e-179 M LicD family
KHCPIEKB_00999 2e-85 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
KHCPIEKB_01000 9.1e-226
KHCPIEKB_01002 9.8e-200 S DUF218 domain
KHCPIEKB_01003 2.9e-122 S CAAX protease self-immunity
KHCPIEKB_01004 3.2e-201 napA P Sodium/hydrogen exchanger family
KHCPIEKB_01005 0.0 cadA P P-type ATPase
KHCPIEKB_01006 1.2e-85 ykuL S (CBS) domain
KHCPIEKB_01007 4.6e-227 ywhK S Membrane
KHCPIEKB_01008 6.8e-53
KHCPIEKB_01010 4.4e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCPIEKB_01011 5.7e-241 dltB M MBOAT, membrane-bound O-acyltransferase family
KHCPIEKB_01012 2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCPIEKB_01013 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHCPIEKB_01014 3.8e-66 S Iron-sulphur cluster biosynthesis
KHCPIEKB_01015 0.0 yhcA V ABC transporter, ATP-binding protein
KHCPIEKB_01016 8.5e-116 K Bacterial regulatory proteins, tetR family
KHCPIEKB_01017 3.3e-289 V ABC transporter transmembrane region
KHCPIEKB_01018 6e-09 S PAS domain
KHCPIEKB_01019 8.6e-47 GK ROK family
KHCPIEKB_01020 1.9e-33 GK ROK family
KHCPIEKB_01022 1.6e-157 dkg S reductase
KHCPIEKB_01023 1.1e-123 endA F DNA RNA non-specific endonuclease
KHCPIEKB_01024 8.2e-44 E dipeptidase activity
KHCPIEKB_01025 8.8e-107
KHCPIEKB_01026 6.4e-87 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KHCPIEKB_01027 7.9e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
KHCPIEKB_01028 6.7e-154 corA P CorA-like Mg2+ transporter protein
KHCPIEKB_01029 1.7e-157 3.5.2.6 V Beta-lactamase enzyme family
KHCPIEKB_01030 4.2e-26
KHCPIEKB_01031 2.3e-99 yobS K Bacterial regulatory proteins, tetR family
KHCPIEKB_01032 0.0 ydgH S MMPL family
KHCPIEKB_01033 3.3e-176
KHCPIEKB_01035 1.3e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KHCPIEKB_01036 2e-54 qorB 1.6.5.2 GM NmrA-like family
KHCPIEKB_01037 2.8e-32 qorB 1.6.5.2 GM epimerase
KHCPIEKB_01038 3.9e-23 K Transcriptional regulator
KHCPIEKB_01039 2.3e-84 S YcxB-like protein
KHCPIEKB_01040 5.4e-103 T integral membrane protein
KHCPIEKB_01041 0.0 L Helicase C-terminal domain protein
KHCPIEKB_01042 2.9e-91 S ECF-type riboflavin transporter, S component
KHCPIEKB_01043 4.7e-154 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KHCPIEKB_01044 4.6e-25 K Acetyltransferase (GNAT) domain
KHCPIEKB_01046 4.9e-255 lysA2 M Glycosyl hydrolases family 25
KHCPIEKB_01047 1.9e-10
KHCPIEKB_01048 7.9e-132 ybbM S Uncharacterised protein family (UPF0014)
KHCPIEKB_01049 2e-112 ybbL S ABC transporter, ATP-binding protein
KHCPIEKB_01051 2e-211 V ABC-type multidrug transport system, ATPase and permease components
KHCPIEKB_01052 1.1e-94 L nuclease
KHCPIEKB_01053 1.1e-153 F DNA/RNA non-specific endonuclease
KHCPIEKB_01054 3.3e-11
KHCPIEKB_01055 1.6e-86 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHCPIEKB_01056 7.3e-104 KQ Hypothetical methyltransferase
KHCPIEKB_01057 1.3e-67 KQ Hypothetical methyltransferase
KHCPIEKB_01058 2.3e-206 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHCPIEKB_01059 2.4e-156 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHCPIEKB_01060 4.8e-116 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KHCPIEKB_01061 5.6e-183 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KHCPIEKB_01062 1.5e-19 higA K Helix-turn-helix XRE-family like proteins
KHCPIEKB_01063 3.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KHCPIEKB_01064 2.3e-94 S ABC transporter, ATP-binding protein
KHCPIEKB_01065 2.8e-85 XK27_00670 S ABC transporter
KHCPIEKB_01066 9.7e-23 XK27_00670 S ABC transporter
KHCPIEKB_01067 1.7e-26 XK27_00670 S ABC transporter
KHCPIEKB_01069 1.1e-26
KHCPIEKB_01070 7.7e-31 brnQ U Component of the transport system for branched-chain amino acids
KHCPIEKB_01071 1.1e-22 brnQ U Component of the transport system for branched-chain amino acids
KHCPIEKB_01072 2.1e-128 5.99.1.2 T diguanylate cyclase
KHCPIEKB_01073 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
KHCPIEKB_01074 8.6e-37
KHCPIEKB_01075 1.4e-129 cobQ S glutamine amidotransferase
KHCPIEKB_01076 1.5e-75 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHCPIEKB_01077 6.2e-134 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHCPIEKB_01078 4e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
KHCPIEKB_01079 0.0 KLT serine threonine protein kinase
KHCPIEKB_01080 7.2e-289 V ABC-type multidrug transport system, ATPase and permease components
KHCPIEKB_01081 1.2e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
KHCPIEKB_01082 9.9e-91 ymdB S Macro domain protein
KHCPIEKB_01083 1.1e-151
KHCPIEKB_01085 2.5e-264 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KHCPIEKB_01086 8.6e-257 P Sodium:sulfate symporter transmembrane region
KHCPIEKB_01088 3.4e-94 pipD M Peptidase family C69
KHCPIEKB_01089 3.1e-133 pipD M Peptidase family C69
KHCPIEKB_01090 1.8e-173 citR K Putative sugar-binding domain
KHCPIEKB_01091 6.6e-36 lysM M LysM domain
KHCPIEKB_01092 0.0 pepN 3.4.11.2 E aminopeptidase
KHCPIEKB_01093 2.8e-28 drgA C coenzyme F420-1:gamma-L-glutamate ligase activity
KHCPIEKB_01094 7.7e-14 drgA C Nitroreductase family
KHCPIEKB_01095 8.6e-226 S Putative peptidoglycan binding domain
KHCPIEKB_01096 6e-117
KHCPIEKB_01097 1.9e-138 S Belongs to the UPF0246 family
KHCPIEKB_01098 5.6e-18 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
KHCPIEKB_01099 9e-47 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
KHCPIEKB_01100 3.8e-64 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
KHCPIEKB_01101 2.1e-88 ygfC K transcriptional regulator (TetR family)
KHCPIEKB_01102 7.7e-186 hrtB V ABC transporter permease
KHCPIEKB_01103 4.4e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KHCPIEKB_01104 8e-171 K WYL domain
KHCPIEKB_01105 1.3e-66 S pyridoxamine 5-phosphate
KHCPIEKB_01106 5.9e-11 K LytTr DNA-binding domain
KHCPIEKB_01107 1.3e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHCPIEKB_01108 6.3e-140
KHCPIEKB_01110 4.2e-110
KHCPIEKB_01111 9.6e-118 V AAA domain, putative AbiEii toxin, Type IV TA system
KHCPIEKB_01112 1.1e-16
KHCPIEKB_01113 1.6e-276 pipD E Dipeptidase
KHCPIEKB_01114 1.5e-97 K WHG domain
KHCPIEKB_01115 2.6e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
KHCPIEKB_01116 5e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
KHCPIEKB_01117 1.6e-143 3.1.3.48 T Tyrosine phosphatase family
KHCPIEKB_01118 6.8e-189 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHCPIEKB_01119 2.4e-87 cvpA S Colicin V production protein
KHCPIEKB_01120 7.4e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KHCPIEKB_01121 6.7e-145 noc K Belongs to the ParB family
KHCPIEKB_01122 2.6e-138 soj D Sporulation initiation inhibitor
KHCPIEKB_01123 3.1e-156 spo0J K Belongs to the ParB family
KHCPIEKB_01124 2.5e-45 yyzM S Bacterial protein of unknown function (DUF951)
KHCPIEKB_01125 6.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHCPIEKB_01126 1.8e-136 XK27_01040 S Protein of unknown function (DUF1129)
KHCPIEKB_01127 0.0 V ABC transporter, ATP-binding protein
KHCPIEKB_01128 0.0 ndvA V ABC transporter
KHCPIEKB_01129 1e-122 K response regulator
KHCPIEKB_01130 6.5e-221 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
KHCPIEKB_01131 6.4e-298 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHCPIEKB_01132 1.4e-144 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KHCPIEKB_01133 9.8e-135 fruR K DeoR C terminal sensor domain
KHCPIEKB_01134 4.5e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KHCPIEKB_01135 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
KHCPIEKB_01136 1e-145 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
KHCPIEKB_01137 8.6e-119 fhuC P ABC transporter
KHCPIEKB_01138 8e-135 znuB U ABC 3 transport family
KHCPIEKB_01139 8.3e-49 KT response to antibiotic
KHCPIEKB_01140 9.2e-99 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KHCPIEKB_01141 0.0 pepF E oligoendopeptidase F
KHCPIEKB_01142 4.9e-251 L Putative transposase DNA-binding domain
KHCPIEKB_01143 3.5e-208 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHCPIEKB_01144 7.9e-16
KHCPIEKB_01145 3.3e-294 S ABC transporter, ATP-binding protein
KHCPIEKB_01146 2.8e-137 thrE S Putative threonine/serine exporter
KHCPIEKB_01147 2.7e-85 S Threonine/Serine exporter, ThrE
KHCPIEKB_01148 1.4e-68
KHCPIEKB_01149 2.2e-111
KHCPIEKB_01150 2.2e-290 S O-antigen ligase like membrane protein
KHCPIEKB_01151 7.2e-45
KHCPIEKB_01152 2.9e-96 gmk2 2.7.4.8 F Guanylate kinase homologues.
KHCPIEKB_01153 2.8e-82 M NlpC P60 family
KHCPIEKB_01154 6.4e-201 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCPIEKB_01155 6.7e-81 M NlpC/P60 family
KHCPIEKB_01156 1.2e-106 M NlpC P60 family protein
KHCPIEKB_01157 1.8e-122 M NlpC P60 family protein
KHCPIEKB_01158 1.2e-119 M NlpC P60 family protein
KHCPIEKB_01159 2.2e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHCPIEKB_01160 1.4e-179 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHCPIEKB_01161 6.7e-116 epsB M biosynthesis protein
KHCPIEKB_01162 1e-115 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KHCPIEKB_01163 2.3e-147 ywqE 3.1.3.48 GM PHP domain protein
KHCPIEKB_01164 1.9e-121 rfbP M Bacterial sugar transferase
KHCPIEKB_01165 6.6e-165 rgpAc GT4 M Domain of unknown function (DUF1972)
KHCPIEKB_01166 9.8e-154 G Glycosyltransferase Family 4
KHCPIEKB_01167 6.2e-53 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
KHCPIEKB_01168 8.9e-87 gtb M transferase activity, transferring glycosyl groups
KHCPIEKB_01169 3e-93 rgpB GT2 S Glycosyl transferase family 2
KHCPIEKB_01170 1.4e-117 L Transposase
KHCPIEKB_01171 4.6e-31 L Transposase
KHCPIEKB_01173 1.7e-50 M Glycosyl-transferase family 4
KHCPIEKB_01174 2.8e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHCPIEKB_01175 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHCPIEKB_01176 4.2e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KHCPIEKB_01177 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHCPIEKB_01178 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHCPIEKB_01179 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KHCPIEKB_01180 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KHCPIEKB_01181 1e-18 L haloacid dehalogenase-like hydrolase
KHCPIEKB_01182 2.8e-57 S glycolate biosynthetic process
KHCPIEKB_01183 4.6e-162 xth 3.1.11.2 L exodeoxyribonuclease III
KHCPIEKB_01184 5.6e-74
KHCPIEKB_01185 4.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KHCPIEKB_01186 6.7e-164 yvgN C Aldo keto reductase
KHCPIEKB_01187 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
KHCPIEKB_01188 7e-14 S Domain of unknown function (DUF4430)
KHCPIEKB_01189 4.7e-94 S ECF transporter, substrate-specific component
KHCPIEKB_01190 1.3e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
KHCPIEKB_01191 7e-153 S Protein of unknown function (DUF3298)
KHCPIEKB_01192 6.5e-99 K Sigma-70 region 2
KHCPIEKB_01193 5.9e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHCPIEKB_01194 3.6e-93 J Acetyltransferase (GNAT) domain
KHCPIEKB_01195 4.4e-106 yjbF S SNARE associated Golgi protein
KHCPIEKB_01196 2.9e-153 I alpha/beta hydrolase fold
KHCPIEKB_01197 1.4e-156 hipB K Helix-turn-helix
KHCPIEKB_01198 8.6e-95 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
KHCPIEKB_01199 1.7e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
KHCPIEKB_01200 9.5e-153
KHCPIEKB_01201 1.1e-147 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHCPIEKB_01202 1.2e-48 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHCPIEKB_01203 1e-90 1.2.3.3, 3.7.1.22 EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
KHCPIEKB_01205 5.6e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KHCPIEKB_01206 5.6e-158 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHCPIEKB_01207 2.6e-230 M ErfK YbiS YcfS YnhG
KHCPIEKB_01209 6.1e-145 lysR7 K LysR substrate binding domain
KHCPIEKB_01210 1e-98 dam2 2.1.1.72 L DNA methyltransferase
KHCPIEKB_01211 1.7e-174 S AAA ATPase domain
KHCPIEKB_01212 7.7e-95 L Transposase and inactivated derivatives
KHCPIEKB_01213 1.3e-54 L Transposase and inactivated derivatives
KHCPIEKB_01214 1.8e-59 XK27_01125 L IS66 Orf2 like protein
KHCPIEKB_01215 3.4e-48
KHCPIEKB_01216 3.6e-57 gepA S Protein of unknown function (DUF4065)
KHCPIEKB_01217 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHCPIEKB_01218 1.3e-293 ytgP S Polysaccharide biosynthesis protein
KHCPIEKB_01219 1.2e-55 ppsA 2.7.9.2 G Belongs to the PEP-utilizing enzyme family
KHCPIEKB_01220 4.8e-60 ppsA 2.7.9.2 G Pyruvate phosphate dikinase, PEP/pyruvate binding domain
KHCPIEKB_01221 2.6e-160 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KHCPIEKB_01222 7.5e-57 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KHCPIEKB_01223 3.4e-67 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KHCPIEKB_01224 2e-239 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHCPIEKB_01225 7.4e-166 S Alpha/beta hydrolase of unknown function (DUF915)
KHCPIEKB_01226 4.4e-149 S Sucrose-6F-phosphate phosphohydrolase
KHCPIEKB_01227 1.1e-113 puuD S peptidase C26
KHCPIEKB_01228 5.1e-14 puuD S peptidase C26
KHCPIEKB_01229 5.3e-159 yicL EG EamA-like transporter family
KHCPIEKB_01230 5.7e-49 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KHCPIEKB_01231 2.3e-30 cspA K Cold shock protein
KHCPIEKB_01232 2.5e-115 galR K Transcriptional regulator
KHCPIEKB_01233 1.2e-46 K purine nucleotide biosynthetic process
KHCPIEKB_01234 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KHCPIEKB_01235 0.0 lacS G Transporter
KHCPIEKB_01236 7.2e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHCPIEKB_01237 8.6e-284 thrC 4.2.3.1 E Threonine synthase
KHCPIEKB_01241 7.2e-100 K Acetyltransferase (GNAT) domain
KHCPIEKB_01242 1.5e-106 yiiE S Protein of unknown function (DUF1211)
KHCPIEKB_01243 7.7e-25
KHCPIEKB_01244 2.4e-95 scrR K Transcriptional regulator, LacI family
KHCPIEKB_01245 4.5e-15 scrR K Transcriptional regulator, LacI family
KHCPIEKB_01246 2.5e-70 S SLAP domain
KHCPIEKB_01247 2.2e-196 tcsA S ABC transporter substrate-binding protein PnrA-like
KHCPIEKB_01248 1e-70 S Domain of unknown function (DUF4352)
KHCPIEKB_01249 3.4e-186 KLT Protein tyrosine kinase
KHCPIEKB_01250 5.2e-66 S Psort location Cytoplasmic, score
KHCPIEKB_01252 3.1e-198 tcsA S ABC transporter substrate-binding protein PnrA-like
KHCPIEKB_01253 0.0 XK27_08315 M Sulfatase
KHCPIEKB_01254 2.9e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHCPIEKB_01255 1.7e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHCPIEKB_01256 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHCPIEKB_01257 2e-132
KHCPIEKB_01258 1.5e-35 S inositol 2-dehydrogenase activity
KHCPIEKB_01259 3.4e-64 S Oxidoreductase
KHCPIEKB_01260 0.0 yjbQ P TrkA C-terminal domain protein
KHCPIEKB_01261 3.1e-263 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KHCPIEKB_01262 2.1e-195 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHCPIEKB_01263 4e-34 S Protein of unknown function (DUF2922)
KHCPIEKB_01264 7.7e-29
KHCPIEKB_01265 1.6e-86
KHCPIEKB_01266 1.7e-72
KHCPIEKB_01267 0.0 kup P Transport of potassium into the cell
KHCPIEKB_01268 0.0 pepO 3.4.24.71 O Peptidase family M13
KHCPIEKB_01269 5e-62 Z012_07300 O Glutaredoxin-related protein
KHCPIEKB_01270 2.5e-228 yttB EGP Major facilitator Superfamily
KHCPIEKB_01271 1.1e-36 XK27_04775 P Hemerythrin HHE cation binding domain protein
KHCPIEKB_01272 9.4e-33 S Iron-sulfur cluster assembly protein
KHCPIEKB_01273 8e-142 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHCPIEKB_01274 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KHCPIEKB_01275 7.6e-249 yxbA 6.3.1.12 S ATP-grasp enzyme
KHCPIEKB_01276 0.0 asnB 6.3.5.4 E Asparagine synthase
KHCPIEKB_01277 1.5e-274 S Calcineurin-like phosphoesterase
KHCPIEKB_01278 5.1e-84
KHCPIEKB_01279 1.3e-288 oppA E ABC transporter, substratebinding protein
KHCPIEKB_01280 4.9e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KHCPIEKB_01281 7.5e-125 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KHCPIEKB_01282 3.3e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KHCPIEKB_01283 2.3e-157 phnD P Phosphonate ABC transporter
KHCPIEKB_01284 5.5e-83 uspA T universal stress protein
KHCPIEKB_01285 1.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
KHCPIEKB_01286 2.9e-84 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHCPIEKB_01287 3e-89 ntd 2.4.2.6 F Nucleoside
KHCPIEKB_01288 1.2e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHCPIEKB_01289 0.0 G Belongs to the glycosyl hydrolase 31 family
KHCPIEKB_01290 1.1e-83 malG P ABC transporter permease
KHCPIEKB_01291 6.8e-104 malF P Binding-protein-dependent transport system inner membrane component
KHCPIEKB_01292 9.3e-100 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
KHCPIEKB_01293 1.3e-170 I alpha/beta hydrolase fold
KHCPIEKB_01294 3.4e-130 yibF S overlaps another CDS with the same product name
KHCPIEKB_01295 5.8e-184 yibE S overlaps another CDS with the same product name
KHCPIEKB_01296 2.6e-43
KHCPIEKB_01297 3.4e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KHCPIEKB_01298 1.5e-199 S Cysteine-rich secretory protein family
KHCPIEKB_01299 3e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KHCPIEKB_01300 1.2e-144
KHCPIEKB_01301 3.4e-126 luxT K Bacterial regulatory proteins, tetR family
KHCPIEKB_01302 5.2e-184 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHCPIEKB_01303 2.8e-125 S Alpha/beta hydrolase family
KHCPIEKB_01304 2.5e-160 epsV 2.7.8.12 S glycosyl transferase family 2
KHCPIEKB_01305 8.3e-163 ypuA S Protein of unknown function (DUF1002)
KHCPIEKB_01306 1.5e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHCPIEKB_01307 5.1e-181 S Alpha/beta hydrolase of unknown function (DUF915)
KHCPIEKB_01308 5.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHCPIEKB_01309 6.1e-82
KHCPIEKB_01310 1.9e-132 cobB K SIR2 family
KHCPIEKB_01311 3.7e-66 yeaO S Protein of unknown function, DUF488
KHCPIEKB_01312 9.4e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KHCPIEKB_01313 1.7e-274 glnP P ABC transporter permease
KHCPIEKB_01314 3.5e-140 glnQ E ABC transporter, ATP-binding protein
KHCPIEKB_01315 6.5e-114 CBM50 M NlpC P60 family protein
KHCPIEKB_01316 1.5e-174 L HNH nucleases
KHCPIEKB_01317 1.2e-14
KHCPIEKB_01318 2.7e-200 ybiR P Citrate transporter
KHCPIEKB_01319 1.6e-94 lemA S LemA family
KHCPIEKB_01320 8.4e-149 htpX O Belongs to the peptidase M48B family
KHCPIEKB_01321 1.2e-152 mutR K Helix-turn-helix XRE-family like proteins
KHCPIEKB_01322 1.3e-221 S ATP diphosphatase activity
KHCPIEKB_01323 2.5e-138 S ABC-2 family transporter protein
KHCPIEKB_01324 5.4e-109 S ABC-2 family transporter protein
KHCPIEKB_01325 9.5e-172 natA1 S ABC transporter
KHCPIEKB_01326 1e-151 K helix_turn_helix, arabinose operon control protein
KHCPIEKB_01327 1.7e-271 emrY EGP Major facilitator Superfamily
KHCPIEKB_01328 5.5e-253 cbiO1 S ABC transporter, ATP-binding protein
KHCPIEKB_01329 3.2e-113 P Cobalt transport protein
KHCPIEKB_01330 2e-17 L Transposase
KHCPIEKB_01331 1.6e-120 S Membrane protein involved in the export of O-antigen and teichoic acid
KHCPIEKB_01332 5.2e-16 S Transposase C of IS166 homeodomain
KHCPIEKB_01333 5.4e-215 L Transposase and inactivated derivatives
KHCPIEKB_01334 2.5e-49 XK27_01125 L IS66 Orf2 like protein
KHCPIEKB_01335 4.6e-22
KHCPIEKB_01337 1.8e-206 S amidohydrolase
KHCPIEKB_01338 3.5e-14 XK27_07210 6.1.1.6 S B3 4 domain
KHCPIEKB_01339 5.3e-47 E Arginine ornithine antiporter
KHCPIEKB_01340 3.2e-106 E Arginine ornithine antiporter
KHCPIEKB_01356 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KHCPIEKB_01357 3.2e-211 pepO 3.4.24.71 O Peptidase family M13
KHCPIEKB_01358 8.5e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KHCPIEKB_01359 9.5e-61
KHCPIEKB_01362 1.1e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHCPIEKB_01363 1.5e-261 mdr EGP Sugar (and other) transporter
KHCPIEKB_01364 7.8e-120 3.6.1.27 I Acid phosphatase homologues
KHCPIEKB_01366 2.4e-74 L Putative transposase DNA-binding domain
KHCPIEKB_01367 5.1e-246 nhaC C Na H antiporter NhaC
KHCPIEKB_01368 7.5e-146 2.7.7.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KHCPIEKB_01369 1.6e-42 L Membrane
KHCPIEKB_01370 2.2e-107
KHCPIEKB_01371 1.3e-107 pncA Q Isochorismatase family
KHCPIEKB_01372 2e-56 asnB 6.3.5.4 E Aluminium induced protein
KHCPIEKB_01373 1.1e-230 asnB 6.3.5.4 E Aluminium induced protein
KHCPIEKB_01374 1.4e-161 spoU 2.1.1.185 J Methyltransferase
KHCPIEKB_01375 3.8e-38 C FAD linked oxidase domain protein
KHCPIEKB_01376 1.2e-146 1.1.3.15 C FAD linked oxidases, C-terminal domain
KHCPIEKB_01377 6e-188 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCPIEKB_01378 4.2e-74 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHCPIEKB_01379 3e-143 metQ_4 P Belongs to the nlpA lipoprotein family
KHCPIEKB_01380 4.2e-91 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHCPIEKB_01381 6e-54 ribD 1.1.1.193, 3.5.4.26 H MafB19-like deaminase
KHCPIEKB_01382 2.7e-29 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHCPIEKB_01383 8.1e-30 P metal ion transport
KHCPIEKB_01385 1.8e-30 D nuclear chromosome segregation
KHCPIEKB_01388 8.8e-287 V ABC transporter transmembrane region
KHCPIEKB_01389 3.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KHCPIEKB_01390 8.8e-57 asp S Asp23 family, cell envelope-related function
KHCPIEKB_01391 2.7e-278 yloV S DAK2 domain fusion protein YloV
KHCPIEKB_01392 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHCPIEKB_01393 7.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KHCPIEKB_01394 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHCPIEKB_01395 3.7e-190 oppD P Belongs to the ABC transporter superfamily
KHCPIEKB_01396 2.4e-178 oppF P Belongs to the ABC transporter superfamily
KHCPIEKB_01397 3.8e-176 oppB P ABC transporter permease
KHCPIEKB_01398 1.3e-157 oppC P Binding-protein-dependent transport system inner membrane component
KHCPIEKB_01399 0.0 oppA1 E ABC transporter substrate-binding protein
KHCPIEKB_01400 0.0 oppA E ABC transporter substrate-binding protein
KHCPIEKB_01401 3.1e-127 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHCPIEKB_01402 0.0 smc D Required for chromosome condensation and partitioning
KHCPIEKB_01403 2.3e-155 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHCPIEKB_01404 2.5e-88 pipD E Dipeptidase
KHCPIEKB_01405 1.5e-73 pipD E Dipeptidase
KHCPIEKB_01406 8.6e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHCPIEKB_01407 1.2e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHCPIEKB_01408 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KHCPIEKB_01409 1.8e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHCPIEKB_01410 1.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KHCPIEKB_01411 1.8e-09 CP_1020 S Psort location Cytoplasmic, score 8.87
KHCPIEKB_01412 3.2e-11 snf 2.7.11.1 KL domain protein
KHCPIEKB_01413 0.0 snf 2.7.11.1 KL domain protein
KHCPIEKB_01414 5.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHCPIEKB_01415 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
KHCPIEKB_01416 0.0 S TerB-C domain
KHCPIEKB_01417 1.4e-248 P P-loop Domain of unknown function (DUF2791)
KHCPIEKB_01418 0.0 lhr L DEAD DEAH box helicase
KHCPIEKB_01419 3.4e-97
KHCPIEKB_01420 1.3e-154 glnH ET ABC transporter substrate-binding protein
KHCPIEKB_01421 7.9e-149 glcU U ribose uptake protein RbsU
KHCPIEKB_01422 3.5e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHCPIEKB_01423 1.5e-33 ynzC S UPF0291 protein
KHCPIEKB_01424 2.3e-31 yneF S Uncharacterised protein family (UPF0154)
KHCPIEKB_01425 0.0 mdlA V ABC transporter
KHCPIEKB_01426 0.0 mdlB V ABC transporter
KHCPIEKB_01427 2.6e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
KHCPIEKB_01428 1.6e-213 hom 1.1.1.3 E homoserine dehydrogenase
KHCPIEKB_01429 1.3e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
KHCPIEKB_01430 4.8e-182 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHCPIEKB_01431 1.4e-115 plsC 2.3.1.51 I Acyltransferase
KHCPIEKB_01432 2.2e-190 yabB 2.1.1.223 L Methyltransferase small domain
KHCPIEKB_01433 1.4e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
KHCPIEKB_01434 5.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHCPIEKB_01435 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KHCPIEKB_01436 2.9e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHCPIEKB_01437 7.6e-124 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHCPIEKB_01438 1.1e-144 cdsA 2.7.7.41 S Belongs to the CDS family
KHCPIEKB_01439 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KHCPIEKB_01440 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHCPIEKB_01441 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHCPIEKB_01442 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
KHCPIEKB_01443 6.8e-194 nusA K Participates in both transcription termination and antitermination
KHCPIEKB_01444 4.3e-43 ylxR K Protein of unknown function (DUF448)
KHCPIEKB_01445 4.8e-42 rplGA J ribosomal protein
KHCPIEKB_01446 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHCPIEKB_01447 5.5e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHCPIEKB_01448 1.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHCPIEKB_01449 8.4e-54 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
KHCPIEKB_01450 7e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KHCPIEKB_01451 3.9e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KHCPIEKB_01452 7.4e-32 S Uncharacterised protein family (UPF0236)
KHCPIEKB_01453 4.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHCPIEKB_01454 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHCPIEKB_01455 5.4e-26 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
KHCPIEKB_01456 3.3e-233 isp2 L Transposase
KHCPIEKB_01457 5.7e-197 S Acyltransferase family
KHCPIEKB_01458 1.8e-74
KHCPIEKB_01459 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHCPIEKB_01461 5e-173 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
KHCPIEKB_01462 1.6e-51 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KHCPIEKB_01463 6e-143 G polysaccharide deacetylase
KHCPIEKB_01464 1.9e-15 G Polysaccharide deacetylase
KHCPIEKB_01467 4e-49 S Domain of Unknown Function with PDB structure (DUF3862)
KHCPIEKB_01469 2.6e-123 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KHCPIEKB_01470 2.1e-126 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KHCPIEKB_01471 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KHCPIEKB_01472 1.7e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHCPIEKB_01473 1.4e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KHCPIEKB_01474 1.9e-77 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KHCPIEKB_01475 1e-68 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KHCPIEKB_01476 1.4e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KHCPIEKB_01477 6.3e-123 IQ reductase
KHCPIEKB_01478 7.4e-180 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KHCPIEKB_01479 1e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHCPIEKB_01480 3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHCPIEKB_01481 7.3e-184 K AI-2E family transporter
KHCPIEKB_01482 0.0 S Predicted membrane protein (DUF2207)
KHCPIEKB_01483 4.9e-15
KHCPIEKB_01484 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KHCPIEKB_01485 2.3e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
KHCPIEKB_01486 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHCPIEKB_01487 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHCPIEKB_01488 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
KHCPIEKB_01489 3.8e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHCPIEKB_01490 2e-226 yjjP S Putative threonine/serine exporter
KHCPIEKB_01491 4.8e-221 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KHCPIEKB_01492 1.5e-217 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KHCPIEKB_01493 1.3e-196 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KHCPIEKB_01494 5.7e-228 sptS 2.7.13.3 T Histidine kinase
KHCPIEKB_01495 8.2e-117 K response regulator
KHCPIEKB_01496 8.6e-113 2.7.6.5 T Region found in RelA / SpoT proteins
KHCPIEKB_01497 5.6e-158 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
KHCPIEKB_01498 1.2e-174 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KHCPIEKB_01499 6.9e-118 casE S CRISPR_assoc
KHCPIEKB_01500 1.6e-131 casD S CRISPR-associated protein (Cas_Cas5)
KHCPIEKB_01501 4.5e-181 casC L CT1975-like protein
KHCPIEKB_01502 1.4e-107 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
KHCPIEKB_01503 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
KHCPIEKB_01504 0.0 cas3 L CRISPR-associated helicase cas3
KHCPIEKB_01506 5e-18
KHCPIEKB_01508 9.4e-202 argH 2.3.1.1, 4.3.2.1 E argininosuccinate lyase
KHCPIEKB_01510 7e-71
KHCPIEKB_01511 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHCPIEKB_01512 1.5e-26
KHCPIEKB_01513 2.3e-116 K DNA-binding transcription factor activity
KHCPIEKB_01514 4.7e-171 K LysR substrate binding domain
KHCPIEKB_01515 0.0 S Bacterial membrane protein YfhO
KHCPIEKB_01516 3.9e-229 S Tetratricopeptide repeat protein
KHCPIEKB_01517 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHCPIEKB_01518 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KHCPIEKB_01519 8.4e-213 rpsA 1.17.7.4 J Ribosomal protein S1
KHCPIEKB_01520 3.9e-108 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KHCPIEKB_01522 8.6e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHCPIEKB_01523 9.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KHCPIEKB_01524 3.4e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHCPIEKB_01525 6e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHCPIEKB_01526 8.9e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCPIEKB_01527 1.8e-164 xerD D recombinase XerD
KHCPIEKB_01528 4e-164 cvfB S S1 domain
KHCPIEKB_01529 5.6e-89 I Acyltransferase family
KHCPIEKB_01531 5.9e-39 ssuB P anion transmembrane transporter activity
KHCPIEKB_01532 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KHCPIEKB_01533 2e-180 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KHCPIEKB_01534 0.0 dnaE 2.7.7.7 L DNA polymerase
KHCPIEKB_01535 4.3e-29 S Protein of unknown function (DUF2929)
KHCPIEKB_01536 1.7e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
KHCPIEKB_01537 9.2e-30 dedA 3.1.3.1 S SNARE associated Golgi protein
KHCPIEKB_01539 1.8e-84
KHCPIEKB_01540 8.4e-81 K GNAT family
KHCPIEKB_01541 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
KHCPIEKB_01542 9.9e-51 4.4.1.8 E Aminotransferase, class I
KHCPIEKB_01543 2.2e-156 4.4.1.8 E Aminotransferase, class I
KHCPIEKB_01544 3.1e-167 htpX O Peptidase family M48
KHCPIEKB_01545 3.6e-88 1.6.5.2 GM NmrA-like family
KHCPIEKB_01546 3e-78 K Transcriptional regulator
KHCPIEKB_01547 2.3e-170 E ABC transporter, ATP-binding protein
KHCPIEKB_01548 1.1e-278 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KHCPIEKB_01549 3.2e-267 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KHCPIEKB_01550 1.4e-37 metA 2.3.1.46 E L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KHCPIEKB_01551 1.5e-114 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KHCPIEKB_01552 5.6e-138 prsW S Involved in the degradation of specific anti-sigma factors
KHCPIEKB_01553 6.6e-113 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHCPIEKB_01554 3.4e-26
KHCPIEKB_01555 3.2e-138
KHCPIEKB_01556 7.4e-175
KHCPIEKB_01557 3.2e-267 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
KHCPIEKB_01558 7.1e-158 3.4.17.13 V LD-carboxypeptidase
KHCPIEKB_01560 2.8e-11 D Filamentation induced by cAMP protein fic
KHCPIEKB_01561 2.5e-09 D Filamentation induced by cAMP protein fic
KHCPIEKB_01562 1.7e-76 1.3.5.4 C FMN_bind
KHCPIEKB_01563 1.1e-106 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
KHCPIEKB_01564 9.1e-144 ydcF S Gram-negative-bacterium-type cell wall biogenesis
KHCPIEKB_01565 1.7e-56 yyaQ S YjbR
KHCPIEKB_01566 4e-147 ligA 2.7.7.7, 6.5.1.2 L EXOIII
KHCPIEKB_01567 3.9e-136 C FAD binding domain
KHCPIEKB_01569 1.8e-133 gph 3.1.3.18 S HAD-hyrolase-like
KHCPIEKB_01570 2.4e-43 yjdJ S GCN5-related N-acetyl-transferase
KHCPIEKB_01572 8.4e-63 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHCPIEKB_01573 7.2e-175 rnhA 3.1.26.4 L Resolvase, N-terminal
KHCPIEKB_01574 3.5e-69 rnhA 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
KHCPIEKB_01575 2.8e-51 P Rhodanese Homology Domain
KHCPIEKB_01576 0.0 V ABC transporter transmembrane region
KHCPIEKB_01577 2.6e-308 XK27_09600 V ABC transporter, ATP-binding protein
KHCPIEKB_01578 2.3e-78 K Transcriptional regulator, MarR family
KHCPIEKB_01579 1.5e-166 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCPIEKB_01580 2.9e-78 V Psort location CytoplasmicMembrane, score
KHCPIEKB_01581 4.1e-167 V Psort location CytoplasmicMembrane, score 10.00
KHCPIEKB_01582 5.9e-46 V (ABC) transporter
KHCPIEKB_01583 1.4e-113 ylbE GM NAD(P)H-binding
KHCPIEKB_01584 4.5e-120 S Hydrolases of the alpha beta superfamily
KHCPIEKB_01585 3.3e-59
KHCPIEKB_01586 0.0 yacH D Putative exonuclease SbcCD, C subunit
KHCPIEKB_01589 1.1e-19 S Protein of unknown function N-terminus (DUF3323)
KHCPIEKB_01590 2.5e-46
KHCPIEKB_01591 4.9e-27
KHCPIEKB_01593 2.1e-76 K Transcriptional regulator
KHCPIEKB_01594 7.9e-88 WQ51_05710 S Mitochondrial biogenesis AIM24
KHCPIEKB_01595 4.1e-17 oppA2 E transmembrane transport
KHCPIEKB_01596 4.7e-190 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KHCPIEKB_01598 4.4e-94 ybaJ Q Hypothetical methyltransferase
KHCPIEKB_01599 2.6e-35 V (ABC) transporter
KHCPIEKB_01600 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KHCPIEKB_01602 1.1e-157 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHCPIEKB_01603 1.3e-24 carA 6.3.5.5 F carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHCPIEKB_01604 8.6e-37 T diguanylate cyclase activity
KHCPIEKB_01606 7.6e-212 V MATE efflux family protein
KHCPIEKB_01607 6.1e-73 prpH 3.1.3.16 K 3.5.2 Transcription regulation
KHCPIEKB_01608 6.2e-74 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KHCPIEKB_01609 2.5e-106 L Integrase
KHCPIEKB_01610 7.6e-58 XK27_03610 K Acetyltransferase (GNAT) domain
KHCPIEKB_01611 6.4e-69 cylB V ABC-2 type transporter
KHCPIEKB_01612 1.8e-78 S Psort location CytoplasmicMembrane, score
KHCPIEKB_01613 2.7e-76
KHCPIEKB_01614 3.1e-71 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
KHCPIEKB_01615 5.6e-130 cysA V ABC transporter, ATP-binding protein
KHCPIEKB_01616 0.0 V FtsX-like permease family
KHCPIEKB_01617 5.4e-13 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
KHCPIEKB_01618 1.8e-28 K Bacterial regulatory helix-turn-helix protein, lysR family
KHCPIEKB_01619 3.3e-83 1.3.5.4 C FAD binding domain
KHCPIEKB_01620 9.8e-194 1.3.5.4 C FAD binding domain
KHCPIEKB_01621 2.6e-09 S Motility quorum-sensing regulator, toxin of MqsA
KHCPIEKB_01623 3.2e-106 ydaF J Acetyltransferase (GNAT) domain
KHCPIEKB_01624 1.7e-99 sip L Belongs to the 'phage' integrase family
KHCPIEKB_01625 6.8e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KHCPIEKB_01626 8.7e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHCPIEKB_01627 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHCPIEKB_01628 0.0 dnaK O Heat shock 70 kDa protein
KHCPIEKB_01629 6.8e-172 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHCPIEKB_01630 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHCPIEKB_01631 2.8e-123 srtA 3.4.22.70 M sortase family
KHCPIEKB_01632 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KHCPIEKB_01633 9.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHCPIEKB_01634 2.5e-49 K DNA-binding transcription factor activity
KHCPIEKB_01635 3.1e-156 czcD P cation diffusion facilitator family transporter
KHCPIEKB_01636 1.4e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KHCPIEKB_01637 4.1e-185 S AI-2E family transporter
KHCPIEKB_01638 2.8e-21 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHCPIEKB_01639 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHCPIEKB_01640 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
KHCPIEKB_01641 2.4e-161 lysR5 K LysR substrate binding domain
KHCPIEKB_01642 5.5e-262 glnPH2 P ABC transporter permease
KHCPIEKB_01643 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHCPIEKB_01644 1.6e-103 S Protein of unknown function (DUF4230)
KHCPIEKB_01645 6.9e-184 yjgN S Bacterial protein of unknown function (DUF898)
KHCPIEKB_01646 1.4e-53 S Psort location CytoplasmicMembrane, score
KHCPIEKB_01647 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHCPIEKB_01648 9.8e-152 yitS S Uncharacterised protein, DegV family COG1307
KHCPIEKB_01649 1.6e-100 3.6.1.27 I Acid phosphatase homologues
KHCPIEKB_01650 1.2e-157
KHCPIEKB_01651 3.7e-165 lysR7 K LysR substrate binding domain
KHCPIEKB_01652 1.8e-309 yfiB1 V ABC transporter, ATP-binding protein
KHCPIEKB_01653 0.0 XK27_10035 V ABC transporter
KHCPIEKB_01655 1.2e-09 yliE T Putative diguanylate phosphodiesterase
KHCPIEKB_01656 2.9e-26 yliE T Putative diguanylate phosphodiesterase
KHCPIEKB_01657 3.9e-170 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHCPIEKB_01658 4.1e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KHCPIEKB_01659 4.3e-98 hlyIII S protein, hemolysin III
KHCPIEKB_01660 2.5e-155 DegV S Uncharacterised protein, DegV family COG1307
KHCPIEKB_01661 5.5e-36 yozE S Belongs to the UPF0346 family
KHCPIEKB_01662 7.4e-163 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHCPIEKB_01663 5.7e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHCPIEKB_01664 1.5e-152 dprA LU DNA protecting protein DprA
KHCPIEKB_01665 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHCPIEKB_01666 3e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHCPIEKB_01667 1.4e-164 xerC D Phage integrase, N-terminal SAM-like domain
KHCPIEKB_01668 4e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KHCPIEKB_01669 2.4e-243 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KHCPIEKB_01670 4e-175 lacX 5.1.3.3 G Aldose 1-epimerase
KHCPIEKB_01673 2.8e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHCPIEKB_01674 1.5e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KHCPIEKB_01675 2.2e-08 secY2 U SecY translocase
KHCPIEKB_01677 1.3e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHCPIEKB_01679 1.3e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KHCPIEKB_01680 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KHCPIEKB_01681 7.4e-172 phoH T phosphate starvation-inducible protein PhoH
KHCPIEKB_01682 4.6e-99 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHCPIEKB_01683 2.9e-75 cdd 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KHCPIEKB_01684 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHCPIEKB_01685 2e-135 recO L Involved in DNA repair and RecF pathway recombination
KHCPIEKB_01686 1.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KHCPIEKB_01687 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KHCPIEKB_01688 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHCPIEKB_01689 8.4e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHCPIEKB_01690 7.6e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHCPIEKB_01691 5.7e-203 K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCPIEKB_01692 2.8e-37 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHCPIEKB_01693 1.1e-43 celA 3.2.1.86 GT1 G beta-glucosidase activity
KHCPIEKB_01694 0.0 copB 3.6.3.4 P P-type ATPase
KHCPIEKB_01695 2.2e-64 mdt(A) EGP Major facilitator Superfamily
KHCPIEKB_01696 1.2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHCPIEKB_01697 2.6e-80 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHCPIEKB_01698 4.8e-93 S Sucrose-6F-phosphate phosphohydrolase
KHCPIEKB_01699 3.8e-47 Q phosphatase activity
KHCPIEKB_01700 2.1e-188 ansA 3.5.1.1 EJ L-asparaginase, type I
KHCPIEKB_01701 1.2e-76 K helix_turn_helix multiple antibiotic resistance protein
KHCPIEKB_01703 8.6e-78 ywhH S Aminoacyl-tRNA editing domain
KHCPIEKB_01704 5.5e-172 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KHCPIEKB_01705 2.3e-156 mmuP E amino acid
KHCPIEKB_01706 2.4e-165 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KHCPIEKB_01707 6.2e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
KHCPIEKB_01708 9.3e-132 2.4.2.3 F Phosphorylase superfamily
KHCPIEKB_01710 2.6e-127 tcyB E ABC transporter
KHCPIEKB_01711 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHCPIEKB_01712 3.8e-132 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KHCPIEKB_01715 1.3e-244 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHCPIEKB_01716 1.8e-147 K Transcriptional regulator
KHCPIEKB_01717 8.8e-298 V ABC-type multidrug transport system, ATPase and permease components
KHCPIEKB_01718 2.4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KHCPIEKB_01719 1.2e-203 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHCPIEKB_01720 1.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHCPIEKB_01721 2.1e-225 pbuX F xanthine permease
KHCPIEKB_01722 2.6e-64
KHCPIEKB_01723 4.1e-253 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
KHCPIEKB_01724 3.1e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHCPIEKB_01725 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHCPIEKB_01726 2.1e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHCPIEKB_01727 2.1e-73 hsp O Belongs to the small heat shock protein (HSP20) family
KHCPIEKB_01728 6.5e-259 pepC 3.4.22.40 E Papain family cysteine protease
KHCPIEKB_01729 5.1e-256 pepC 3.4.22.40 E aminopeptidase
KHCPIEKB_01730 2.8e-179 oppF P Belongs to the ABC transporter superfamily
KHCPIEKB_01731 3.9e-198 oppD P Belongs to the ABC transporter superfamily
KHCPIEKB_01732 7.8e-183 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHCPIEKB_01733 2.6e-145 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHCPIEKB_01734 1.1e-300 oppA E ABC transporter
KHCPIEKB_01735 1.5e-110 oppA E ABC transporter, substratebinding protein
KHCPIEKB_01736 1.6e-123 oppA E ABC transporter, substratebinding protein
KHCPIEKB_01737 1.9e-30 oppA E transmembrane transport
KHCPIEKB_01738 1.6e-291 oppA E ABC transporter, substratebinding protein
KHCPIEKB_01739 3.4e-247 oppA E ABC transporter, substratebinding protein
KHCPIEKB_01740 4e-08 oppA E ABC transporter, substratebinding protein
KHCPIEKB_01741 3.1e-121 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHCPIEKB_01742 1.1e-244 N Uncharacterized conserved protein (DUF2075)
KHCPIEKB_01743 2e-197 mmuP E amino acid
KHCPIEKB_01744 3.7e-102 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KHCPIEKB_01745 1.2e-232 amd 3.5.1.47 E Peptidase family M20/M25/M40
KHCPIEKB_01746 2.3e-73 E amino acid
KHCPIEKB_01747 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
KHCPIEKB_01749 6.3e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHCPIEKB_01751 4.5e-160 cjaA ET ABC transporter substrate-binding protein
KHCPIEKB_01752 1.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHCPIEKB_01753 4e-79 P ABC transporter permease
KHCPIEKB_01754 6e-112 papP P ABC transporter, permease protein
KHCPIEKB_01755 1.4e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
KHCPIEKB_01756 6.7e-201 folP 2.5.1.15 H dihydropteroate synthase
KHCPIEKB_01757 6.2e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KHCPIEKB_01758 1.6e-202 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
KHCPIEKB_01759 6.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHCPIEKB_01760 3.9e-19 magIII L Base excision DNA repair protein, HhH-GPD family
KHCPIEKB_01761 2e-26 L Transposase
KHCPIEKB_01762 2e-160 L Putative transposase DNA-binding domain
KHCPIEKB_01763 1.1e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHCPIEKB_01764 1.8e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHCPIEKB_01765 3.3e-86 oppA E ABC transporter, substratebinding protein
KHCPIEKB_01766 4.2e-169 oppA E ABC transporter, substratebinding protein
KHCPIEKB_01767 4.6e-14 P nitric oxide dioxygenase activity
KHCPIEKB_01768 1.2e-85 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHCPIEKB_01770 3.8e-11 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
KHCPIEKB_01771 2.7e-20 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
KHCPIEKB_01772 1.6e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHCPIEKB_01773 3.8e-215 pbpX1 V Beta-lactamase
KHCPIEKB_01774 9.3e-206 pbpX1 V Beta-lactamase
KHCPIEKB_01775 1.9e-14 L Helix-turn-helix domain
KHCPIEKB_01777 1.2e-45
KHCPIEKB_01778 1.6e-172
KHCPIEKB_01779 1.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHCPIEKB_01780 7.2e-112 rsmC 2.1.1.172 J Methyltransferase
KHCPIEKB_01781 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHCPIEKB_01782 4.6e-287 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHCPIEKB_01783 2.7e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHCPIEKB_01784 1.5e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHCPIEKB_01785 1.4e-34 S Protein of unknown function (DUF2508)
KHCPIEKB_01786 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHCPIEKB_01787 2.4e-53 yaaQ S Cyclic-di-AMP receptor
KHCPIEKB_01788 5.4e-161 holB 2.7.7.7 L DNA polymerase III
KHCPIEKB_01789 9.9e-55 yabA L Involved in initiation control of chromosome replication
KHCPIEKB_01790 3.8e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHCPIEKB_01791 2.1e-145 fat 3.1.2.21 I Acyl-ACP thioesterase
KHCPIEKB_01792 3.4e-89 folT S ECF transporter, substrate-specific component
KHCPIEKB_01793 6.8e-90 folT S ECF transporter, substrate-specific component
KHCPIEKB_01794 5.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KHCPIEKB_01795 3.1e-95 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KHCPIEKB_01796 7.6e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHCPIEKB_01797 2.1e-303 uup S ABC transporter, ATP-binding protein
KHCPIEKB_01798 1.3e-122 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHCPIEKB_01799 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHCPIEKB_01800 1.3e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHCPIEKB_01801 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHCPIEKB_01802 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHCPIEKB_01803 8.3e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHCPIEKB_01804 1.6e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHCPIEKB_01805 2.7e-35 yajC U Preprotein translocase
KHCPIEKB_01806 2.9e-284 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHCPIEKB_01807 6.4e-207 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHCPIEKB_01808 4.1e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KHCPIEKB_01809 7.5e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KHCPIEKB_01810 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHCPIEKB_01811 5.7e-42 yrzL S Belongs to the UPF0297 family
KHCPIEKB_01812 1.8e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHCPIEKB_01813 1e-40 yrzB S Belongs to the UPF0473 family
KHCPIEKB_01814 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHCPIEKB_01815 2.7e-54 trxA O Belongs to the thioredoxin family
KHCPIEKB_01816 1.7e-66 yslB S Protein of unknown function (DUF2507)
KHCPIEKB_01817 2.3e-113 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHCPIEKB_01818 2.7e-149 ykuT M mechanosensitive ion channel
KHCPIEKB_01819 5.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHCPIEKB_01820 1.8e-41
KHCPIEKB_01821 5.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KHCPIEKB_01822 4.9e-182 ccpA K catabolite control protein A
KHCPIEKB_01823 5.6e-58
KHCPIEKB_01824 2.7e-279 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KHCPIEKB_01825 8.1e-33 yutD S Protein of unknown function (DUF1027)
KHCPIEKB_01826 2.5e-36 yutD S Protein of unknown function (DUF1027)
KHCPIEKB_01827 4.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KHCPIEKB_01828 3.5e-106 S Protein of unknown function (DUF1461)
KHCPIEKB_01829 8.6e-119 dedA S SNARE-like domain protein
KHCPIEKB_01830 1e-184 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)