ORF_ID e_value Gene_name EC_number CAZy COGs Description
HGHJCLEG_00001 2.3e-31
HGHJCLEG_00002 9.5e-18
HGHJCLEG_00003 3.6e-65
HGHJCLEG_00004 7.9e-34
HGHJCLEG_00005 1.8e-206 potD P ABC transporter
HGHJCLEG_00006 6.5e-140 potC P ABC transporter permease
HGHJCLEG_00007 3.9e-145 potB P ABC transporter permease
HGHJCLEG_00008 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HGHJCLEG_00009 2.8e-50 S amidohydrolase
HGHJCLEG_00010 3.2e-259 K Aminotransferase class I and II
HGHJCLEG_00011 2.2e-48 azlC E azaleucine resistance protein AzlC
HGHJCLEG_00012 1.3e-84 L PFAM transposase IS200-family protein
HGHJCLEG_00013 4.4e-59 azlC E azaleucine resistance protein AzlC
HGHJCLEG_00014 3.2e-50 azlD E Branched-chain amino acid transport
HGHJCLEG_00015 9.5e-113 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HGHJCLEG_00017 9.5e-39 S Cytochrome B5
HGHJCLEG_00018 1.3e-16 L Transposase
HGHJCLEG_00019 1e-36 L Helix-turn-helix domain
HGHJCLEG_00020 3.9e-122 O Zinc-dependent metalloprotease
HGHJCLEG_00021 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGHJCLEG_00022 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
HGHJCLEG_00023 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HGHJCLEG_00024 1.4e-222 G Glycosyl hydrolases family 8
HGHJCLEG_00025 1.2e-241 ydaM M Glycosyl transferase
HGHJCLEG_00027 1.2e-139
HGHJCLEG_00028 3.2e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
HGHJCLEG_00029 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGHJCLEG_00030 1.4e-78 K AsnC family
HGHJCLEG_00031 1.6e-79 uspA T universal stress protein
HGHJCLEG_00032 6.8e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
HGHJCLEG_00033 1.8e-65 ltrA S Bacterial low temperature requirement A protein (LtrA)
HGHJCLEG_00034 3.7e-85 yxjG_1 E methionine synthase, vitamin-B12 independent
HGHJCLEG_00035 8.9e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGHJCLEG_00036 2.7e-222 mdtG EGP Major facilitator Superfamily
HGHJCLEG_00037 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
HGHJCLEG_00038 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGHJCLEG_00039 3.1e-22 S YSIRK type signal peptide
HGHJCLEG_00040 1.2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGHJCLEG_00041 1.3e-218 ecsB U ABC transporter
HGHJCLEG_00042 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HGHJCLEG_00043 3.2e-77 hit FG histidine triad
HGHJCLEG_00045 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
HGHJCLEG_00046 1.8e-56 ytzB S Small secreted protein
HGHJCLEG_00047 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HGHJCLEG_00048 5e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGHJCLEG_00049 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HGHJCLEG_00050 1.9e-119 ybhL S Belongs to the BI1 family
HGHJCLEG_00051 6.8e-74 4.4.1.5 E Glyoxalase
HGHJCLEG_00052 1.4e-136 S Membrane
HGHJCLEG_00053 1.1e-138 S Belongs to the UPF0246 family
HGHJCLEG_00054 6.8e-30 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HGHJCLEG_00055 2.2e-199 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HGHJCLEG_00056 1.4e-23 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HGHJCLEG_00057 6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGHJCLEG_00058 1.8e-166
HGHJCLEG_00059 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGHJCLEG_00060 3e-159 K LysR substrate binding domain protein
HGHJCLEG_00061 1.3e-165 1.1.1.346 C Aldo keto reductase
HGHJCLEG_00062 8.7e-71 XK27_08635 S UPF0210 protein
HGHJCLEG_00063 2.2e-72 XK27_08635 S UPF0210 protein
HGHJCLEG_00064 2.6e-65 XK27_08635 S UPF0210 protein
HGHJCLEG_00065 1.5e-94 K Acetyltransferase (GNAT) domain
HGHJCLEG_00066 8.1e-154 S Alpha beta hydrolase
HGHJCLEG_00067 1.8e-156 gspA M family 8
HGHJCLEG_00068 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGHJCLEG_00069 1.5e-89
HGHJCLEG_00070 9.3e-161 degV S EDD domain protein, DegV family
HGHJCLEG_00071 2.1e-106 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGHJCLEG_00072 0.0 FbpA K Fibronectin-binding protein
HGHJCLEG_00073 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HGHJCLEG_00074 3.6e-207 carA 6.3.5.5 F Belongs to the CarA family
HGHJCLEG_00075 2.9e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGHJCLEG_00076 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGHJCLEG_00077 1.5e-65 esbA S Family of unknown function (DUF5322)
HGHJCLEG_00078 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
HGHJCLEG_00079 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HGHJCLEG_00080 3e-81 F Belongs to the NrdI family
HGHJCLEG_00081 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGHJCLEG_00082 3.2e-101 ypsA S Belongs to the UPF0398 family
HGHJCLEG_00083 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGHJCLEG_00084 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HGHJCLEG_00085 1.3e-160 EG EamA-like transporter family
HGHJCLEG_00086 8.1e-123 dnaD L DnaD domain protein
HGHJCLEG_00087 6.9e-87 ypmB S Protein conserved in bacteria
HGHJCLEG_00088 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HGHJCLEG_00089 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HGHJCLEG_00090 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HGHJCLEG_00091 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HGHJCLEG_00092 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGHJCLEG_00093 2.5e-86 S Protein of unknown function (DUF1440)
HGHJCLEG_00094 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGHJCLEG_00095 1.7e-183 S Phosphotransferase system, EIIC
HGHJCLEG_00098 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGHJCLEG_00099 7.4e-163 yueF S AI-2E family transporter
HGHJCLEG_00100 2e-199 csd1 3.5.1.28 G domain, Protein
HGHJCLEG_00101 2.9e-165 GK ROK family
HGHJCLEG_00102 0.0 tetP J elongation factor G
HGHJCLEG_00103 5.1e-81 uspA T universal stress protein
HGHJCLEG_00104 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HGHJCLEG_00105 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGHJCLEG_00106 3.1e-103 metI P ABC transporter permease
HGHJCLEG_00107 1e-33 3.2.1.17 LO Uncharacterized conserved protein (DUF2075)
HGHJCLEG_00108 0.0 L PLD-like domain
HGHJCLEG_00110 2.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
HGHJCLEG_00111 1.9e-59 yneR
HGHJCLEG_00112 1.6e-101 qorB 1.6.5.2 GM NmrA-like family
HGHJCLEG_00113 3.4e-152 akr5f 1.1.1.346 S reductase
HGHJCLEG_00114 4.9e-111 lssY 3.6.1.27 I Acid phosphatase homologues
HGHJCLEG_00115 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HGHJCLEG_00116 2.7e-66 XK27_01125 L PFAM IS66 Orf2 family protein
HGHJCLEG_00118 2.6e-122 L Integrase core domain
HGHJCLEG_00119 1.4e-109 L Bacterial dnaA protein
HGHJCLEG_00122 4.8e-193 V Beta-lactamase
HGHJCLEG_00123 2.7e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGHJCLEG_00124 7e-104 yhiD S MgtC family
HGHJCLEG_00125 7.3e-13 S GyrI-like small molecule binding domain
HGHJCLEG_00126 5.9e-80 S GyrI-like small molecule binding domain
HGHJCLEG_00127 1.3e-94 L Helix-turn-helix domain
HGHJCLEG_00128 5.2e-119 L hmm pf00665
HGHJCLEG_00132 1.3e-36 EGP Major facilitator Superfamily
HGHJCLEG_00133 6.1e-153 EGP Major facilitator Superfamily
HGHJCLEG_00134 6.2e-67 rmaI K Transcriptional regulator
HGHJCLEG_00135 2.7e-39
HGHJCLEG_00136 0.0 ydaO E amino acid
HGHJCLEG_00137 1.3e-301 ybeC E amino acid
HGHJCLEG_00138 1.3e-79 S Aminoacyl-tRNA editing domain
HGHJCLEG_00139 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGHJCLEG_00140 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGHJCLEG_00142 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGHJCLEG_00143 0.0 uup S ABC transporter, ATP-binding protein
HGHJCLEG_00144 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHJCLEG_00145 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
HGHJCLEG_00146 3.6e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HGHJCLEG_00147 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGHJCLEG_00148 3.8e-216 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGHJCLEG_00149 8e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGHJCLEG_00150 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGHJCLEG_00151 2.9e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HGHJCLEG_00152 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HGHJCLEG_00153 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HGHJCLEG_00154 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHJCLEG_00155 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGHJCLEG_00156 7e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHJCLEG_00157 3.8e-134 fat 3.1.2.21 I Acyl-ACP thioesterase
HGHJCLEG_00158 1.9e-153 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGHJCLEG_00159 3.1e-43 yabA L Involved in initiation control of chromosome replication
HGHJCLEG_00160 2.5e-181 holB 2.7.7.7 L DNA polymerase III
HGHJCLEG_00161 2.9e-51 yaaQ S Cyclic-di-AMP receptor
HGHJCLEG_00162 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGHJCLEG_00163 2.8e-38 S Protein of unknown function (DUF2508)
HGHJCLEG_00164 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGHJCLEG_00165 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGHJCLEG_00166 7.1e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGHJCLEG_00167 0.0 typA T GTP-binding protein TypA
HGHJCLEG_00168 1.3e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HGHJCLEG_00169 1.9e-46 yktA S Belongs to the UPF0223 family
HGHJCLEG_00173 4.1e-55
HGHJCLEG_00180 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
HGHJCLEG_00181 2.2e-152 lmrB EGP Major facilitator Superfamily
HGHJCLEG_00182 2.5e-57 lmrB EGP Major facilitator Superfamily
HGHJCLEG_00183 6e-64 gntR1 K Transcriptional regulator, GntR family
HGHJCLEG_00184 4.4e-155 V ABC transporter, ATP-binding protein
HGHJCLEG_00185 5.5e-116
HGHJCLEG_00186 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HGHJCLEG_00187 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HGHJCLEG_00188 2.8e-224 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HGHJCLEG_00189 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HGHJCLEG_00190 1.2e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HGHJCLEG_00191 3.6e-11
HGHJCLEG_00192 5.3e-131 ponA V Beta-lactamase enzyme family
HGHJCLEG_00193 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGHJCLEG_00194 3.7e-73
HGHJCLEG_00195 3.4e-76 S SIR2-like domain
HGHJCLEG_00196 7.4e-103 S Domain of unknown function DUF87
HGHJCLEG_00197 0.0 oppD EP Psort location Cytoplasmic, score
HGHJCLEG_00198 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HGHJCLEG_00199 5.1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGHJCLEG_00200 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HGHJCLEG_00201 2.3e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HGHJCLEG_00202 2.2e-21
HGHJCLEG_00203 1.3e-262 S Uncharacterized protein conserved in bacteria (DUF2252)
HGHJCLEG_00204 1.1e-169 L transposase, IS605 OrfB family
HGHJCLEG_00206 7.8e-32 L PFAM plasmid pRiA4b ORF-3 family protein
HGHJCLEG_00207 7.7e-227 L PFAM plasmid pRiA4b ORF-3 family protein
HGHJCLEG_00208 9.6e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HGHJCLEG_00209 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGHJCLEG_00210 4.3e-158 mleR K LysR family
HGHJCLEG_00211 8.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HGHJCLEG_00212 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGHJCLEG_00213 4.5e-266 frdC 1.3.5.4 C FAD binding domain
HGHJCLEG_00214 3.5e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHJCLEG_00215 9.3e-203 P Sodium:sulfate symporter transmembrane region
HGHJCLEG_00216 1.4e-125 citR K sugar-binding domain protein
HGHJCLEG_00217 6.1e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HGHJCLEG_00218 1.7e-148 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HGHJCLEG_00219 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
HGHJCLEG_00220 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HGHJCLEG_00221 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HGHJCLEG_00222 3.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HGHJCLEG_00223 3.8e-113 ydjP I Alpha/beta hydrolase family
HGHJCLEG_00224 1.1e-158 mleR K LysR family
HGHJCLEG_00225 9.4e-253 yjjP S Putative threonine/serine exporter
HGHJCLEG_00226 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
HGHJCLEG_00227 6.5e-271 emrY EGP Major facilitator Superfamily
HGHJCLEG_00228 2.7e-185 I Alpha beta
HGHJCLEG_00229 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HGHJCLEG_00230 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGHJCLEG_00232 1.5e-118 yrkL S Flavodoxin-like fold
HGHJCLEG_00233 1.5e-52
HGHJCLEG_00234 5.3e-16 S Domain of unknown function (DUF4767)
HGHJCLEG_00235 1.9e-45 IQ Dehydrogenase reductase
HGHJCLEG_00236 2e-161 S C4-dicarboxylate anaerobic carrier
HGHJCLEG_00237 4e-102 S C4-dicarboxylate anaerobic carrier
HGHJCLEG_00238 2e-274 pipD E Dipeptidase
HGHJCLEG_00239 5.2e-47 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HGHJCLEG_00240 5.9e-73 S ECF transporter, substrate-specific component
HGHJCLEG_00241 9.8e-51 S Domain of unknown function (DUF4430)
HGHJCLEG_00242 5.2e-17 cnrT EG PFAM EamA-like transporter family
HGHJCLEG_00243 1.9e-19 cnrT EG PFAM EamA-like transporter family
HGHJCLEG_00244 1.5e-42 wecD3 K PFAM GCN5-related N-acetyltransferase
HGHJCLEG_00245 3.3e-37 ltrA S Bacterial low temperature requirement A protein (LtrA)
HGHJCLEG_00246 1.5e-40 ltrA S Bacterial low temperature requirement A protein (LtrA)
HGHJCLEG_00247 6.6e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
HGHJCLEG_00248 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHJCLEG_00249 5.1e-139 L Bacterial dnaA protein
HGHJCLEG_00250 1.2e-174 L Integrase core domain
HGHJCLEG_00251 8.2e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HGHJCLEG_00252 4.3e-13
HGHJCLEG_00253 1.6e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HGHJCLEG_00255 1.1e-25
HGHJCLEG_00256 2.7e-67 yqkB S Belongs to the HesB IscA family
HGHJCLEG_00257 8.6e-50 L Transposase IS200 like
HGHJCLEG_00258 5.5e-185 L transposase, IS605 OrfB family
HGHJCLEG_00259 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGHJCLEG_00260 9.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGHJCLEG_00261 0.0 dnaK O Heat shock 70 kDa protein
HGHJCLEG_00262 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGHJCLEG_00263 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGHJCLEG_00264 2.9e-63
HGHJCLEG_00265 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HGHJCLEG_00266 2.7e-163 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGHJCLEG_00267 6.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGHJCLEG_00268 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGHJCLEG_00269 1.3e-48 ylxQ J ribosomal protein
HGHJCLEG_00270 1e-44 ylxR K Protein of unknown function (DUF448)
HGHJCLEG_00271 1.4e-215 nusA K Participates in both transcription termination and antitermination
HGHJCLEG_00272 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
HGHJCLEG_00273 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGHJCLEG_00274 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGHJCLEG_00275 4.1e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HGHJCLEG_00276 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HGHJCLEG_00277 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGHJCLEG_00278 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGHJCLEG_00279 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HGHJCLEG_00280 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGHJCLEG_00281 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HGHJCLEG_00282 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHJCLEG_00283 7.1e-49 yazA L GIY-YIG catalytic domain protein
HGHJCLEG_00284 3.5e-140 yabB 2.1.1.223 L Methyltransferase small domain
HGHJCLEG_00285 1.6e-117 plsC 2.3.1.51 I Acyltransferase
HGHJCLEG_00286 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HGHJCLEG_00287 1.3e-35 ynzC S UPF0291 protein
HGHJCLEG_00288 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGHJCLEG_00289 1.3e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HGHJCLEG_00290 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGHJCLEG_00292 2.5e-93 L Integrase
HGHJCLEG_00294 1.3e-221 L COG3547 Transposase and inactivated derivatives
HGHJCLEG_00295 5.6e-261 S Uncharacterised protein family (UPF0236)
HGHJCLEG_00296 1e-111 frnE Q DSBA-like thioredoxin domain
HGHJCLEG_00297 1e-66 L Uncharacterized conserved protein (DUF2075)
HGHJCLEG_00298 3.9e-182
HGHJCLEG_00300 1.1e-67 cadD P Cadmium resistance transporter
HGHJCLEG_00301 1.9e-56 cadX K Bacterial regulatory protein, arsR family
HGHJCLEG_00302 5.9e-64 yeaO S Protein of unknown function, DUF488
HGHJCLEG_00303 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HGHJCLEG_00304 4.4e-203 3.1.3.1 S associated with various cellular activities
HGHJCLEG_00305 9.6e-231 S Putative metallopeptidase domain
HGHJCLEG_00306 1.9e-46
HGHJCLEG_00307 0.0 pepO 3.4.24.71 O Peptidase family M13
HGHJCLEG_00308 1.4e-105 K Helix-turn-helix XRE-family like proteins
HGHJCLEG_00309 3.9e-87 ymdB S Macro domain protein
HGHJCLEG_00310 3.8e-194 EGP Major facilitator Superfamily
HGHJCLEG_00311 2.3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGHJCLEG_00312 8e-54 K helix_turn_helix, mercury resistance
HGHJCLEG_00313 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGHJCLEG_00314 5.9e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HGHJCLEG_00315 0.0 ysaB V FtsX-like permease family
HGHJCLEG_00316 4.9e-134 macB2 V ABC transporter, ATP-binding protein
HGHJCLEG_00317 2.8e-182 T PhoQ Sensor
HGHJCLEG_00318 1.9e-124 K response regulator
HGHJCLEG_00319 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
HGHJCLEG_00320 2.9e-134 pnuC H nicotinamide mononucleotide transporter
HGHJCLEG_00321 1.2e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGHJCLEG_00322 5.3e-201
HGHJCLEG_00323 2e-52
HGHJCLEG_00324 9.1e-36
HGHJCLEG_00325 1.5e-91 yxkA S Phosphatidylethanolamine-binding protein
HGHJCLEG_00326 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
HGHJCLEG_00327 4.1e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HGHJCLEG_00328 2.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGHJCLEG_00329 3.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HGHJCLEG_00330 5.4e-181 galR K Transcriptional regulator
HGHJCLEG_00331 1.9e-84
HGHJCLEG_00332 9.2e-178 L PFAM Integrase catalytic region
HGHJCLEG_00333 6.9e-104 L PFAM Integrase catalytic region
HGHJCLEG_00334 4.4e-11 L PFAM Integrase catalytic region
HGHJCLEG_00335 4.4e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HGHJCLEG_00336 1.2e-123 S Alpha beta hydrolase
HGHJCLEG_00347 1.5e-80 C Flavodoxin
HGHJCLEG_00348 4.9e-76 yphH S Cupin domain
HGHJCLEG_00349 1.1e-72 yeaL S UPF0756 membrane protein
HGHJCLEG_00350 1.3e-241 EGP Major facilitator Superfamily
HGHJCLEG_00351 5.5e-74 copY K Copper transport repressor CopY TcrY
HGHJCLEG_00352 7.2e-245 yhdP S Transporter associated domain
HGHJCLEG_00353 0.0 ubiB S ABC1 family
HGHJCLEG_00354 1.1e-144 S DUF218 domain
HGHJCLEG_00355 5.4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGHJCLEG_00356 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHJCLEG_00357 5.9e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHJCLEG_00358 0.0 uvrA3 L excinuclease ABC, A subunit
HGHJCLEG_00359 4.3e-121 S SNARE associated Golgi protein
HGHJCLEG_00360 2.3e-229 N Uncharacterized conserved protein (DUF2075)
HGHJCLEG_00361 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGHJCLEG_00363 6.6e-254 yifK E Amino acid permease
HGHJCLEG_00364 1.6e-157 endA V DNA/RNA non-specific endonuclease
HGHJCLEG_00365 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGHJCLEG_00366 2.3e-41 ybaN S Protein of unknown function (DUF454)
HGHJCLEG_00367 7e-72 S Protein of unknown function (DUF3290)
HGHJCLEG_00368 6.2e-114 yviA S Protein of unknown function (DUF421)
HGHJCLEG_00369 2.6e-163 S Alpha/beta hydrolase of unknown function (DUF915)
HGHJCLEG_00370 2e-18
HGHJCLEG_00371 2.1e-90 ntd 2.4.2.6 F Nucleoside
HGHJCLEG_00372 9.6e-152 3.1.3.102, 3.1.3.104 S hydrolase
HGHJCLEG_00373 8.9e-41 yrvD S Pfam:DUF1049
HGHJCLEG_00375 4.3e-35 S Phage derived protein Gp49-like (DUF891)
HGHJCLEG_00376 8.5e-20 K Helix-turn-helix XRE-family like proteins
HGHJCLEG_00377 4e-79 I alpha/beta hydrolase fold
HGHJCLEG_00378 1.7e-100 S Pfam:DUF3816
HGHJCLEG_00379 9.6e-74 elaA S Gnat family
HGHJCLEG_00380 3e-98 xth 3.1.11.2 L exodeoxyribonuclease III
HGHJCLEG_00381 2.3e-35 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HGHJCLEG_00382 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGHJCLEG_00383 5.5e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGHJCLEG_00384 1e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGHJCLEG_00385 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGHJCLEG_00386 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGHJCLEG_00387 5.3e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGHJCLEG_00388 2.9e-162 xerD D recombinase XerD
HGHJCLEG_00389 3.3e-166 cvfB S S1 domain
HGHJCLEG_00390 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HGHJCLEG_00391 0.0 dnaE 2.7.7.7 L DNA polymerase
HGHJCLEG_00392 2e-29 S Protein of unknown function (DUF2929)
HGHJCLEG_00393 2.8e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HGHJCLEG_00394 1.1e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGHJCLEG_00395 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HGHJCLEG_00396 2.4e-220 patA 2.6.1.1 E Aminotransferase
HGHJCLEG_00397 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGHJCLEG_00398 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGHJCLEG_00399 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HGHJCLEG_00400 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HGHJCLEG_00401 3.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HGHJCLEG_00402 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGHJCLEG_00403 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HGHJCLEG_00404 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGHJCLEG_00405 3.2e-181 phoH T phosphate starvation-inducible protein PhoH
HGHJCLEG_00406 1.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGHJCLEG_00407 1.5e-82 bioY S BioY family
HGHJCLEG_00409 1.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGHJCLEG_00410 1.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HGHJCLEG_00411 1.5e-112
HGHJCLEG_00412 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HGHJCLEG_00413 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGHJCLEG_00414 7.3e-86 uspA T Belongs to the universal stress protein A family
HGHJCLEG_00415 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
HGHJCLEG_00416 5.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGHJCLEG_00417 1.1e-300 ytgP S Polysaccharide biosynthesis protein
HGHJCLEG_00418 7.6e-42
HGHJCLEG_00419 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHJCLEG_00420 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGHJCLEG_00421 7.9e-94 tag 3.2.2.20 L glycosylase
HGHJCLEG_00422 1e-257 EGP Major facilitator Superfamily
HGHJCLEG_00423 2.8e-84 perR P Belongs to the Fur family
HGHJCLEG_00424 7.7e-231 cycA E Amino acid permease
HGHJCLEG_00425 1.7e-102 V VanZ like family
HGHJCLEG_00426 1e-23
HGHJCLEG_00427 1.6e-54 S Short repeat of unknown function (DUF308)
HGHJCLEG_00428 2.5e-77 S Psort location Cytoplasmic, score
HGHJCLEG_00429 1.2e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HGHJCLEG_00430 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
HGHJCLEG_00431 5.3e-153 yeaE S Aldo keto
HGHJCLEG_00432 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
HGHJCLEG_00433 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HGHJCLEG_00434 2.7e-21 xth 3.1.11.2 L exodeoxyribonuclease III
HGHJCLEG_00435 1.4e-47 gcvH E glycine cleavage
HGHJCLEG_00436 1.1e-220 rodA D Belongs to the SEDS family
HGHJCLEG_00437 1e-31 S Protein of unknown function (DUF2969)
HGHJCLEG_00438 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HGHJCLEG_00439 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGHJCLEG_00440 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HGHJCLEG_00441 2.9e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HGHJCLEG_00442 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGHJCLEG_00443 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGHJCLEG_00444 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGHJCLEG_00445 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGHJCLEG_00446 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGHJCLEG_00447 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGHJCLEG_00448 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HGHJCLEG_00449 5.9e-233 pyrP F Permease
HGHJCLEG_00450 4.4e-130 yibF S overlaps another CDS with the same product name
HGHJCLEG_00451 1.7e-191 yibE S overlaps another CDS with the same product name
HGHJCLEG_00452 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGHJCLEG_00453 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGHJCLEG_00454 1.1e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGHJCLEG_00455 4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGHJCLEG_00456 6.6e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGHJCLEG_00457 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGHJCLEG_00458 6e-108 tdk 2.7.1.21 F thymidine kinase
HGHJCLEG_00459 6.4e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HGHJCLEG_00460 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HGHJCLEG_00461 6.9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGHJCLEG_00462 6.8e-37 veg S Biofilm formation stimulator VEG
HGHJCLEG_00463 1e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGHJCLEG_00464 1.2e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGHJCLEG_00465 1e-153 tatD L hydrolase, TatD family
HGHJCLEG_00466 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGHJCLEG_00467 1.2e-160 yunF F Protein of unknown function DUF72
HGHJCLEG_00469 4e-130 cobB K SIR2 family
HGHJCLEG_00470 8.6e-176
HGHJCLEG_00471 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HGHJCLEG_00472 4.6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHJCLEG_00473 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHJCLEG_00474 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HGHJCLEG_00475 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
HGHJCLEG_00476 0.0 helD 3.6.4.12 L DNA helicase
HGHJCLEG_00477 4.5e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGHJCLEG_00479 2e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGHJCLEG_00480 5.7e-264 yfnA E amino acid
HGHJCLEG_00481 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGHJCLEG_00482 8.9e-41 1.3.5.4 S FMN binding
HGHJCLEG_00483 8.3e-221 norA EGP Major facilitator Superfamily
HGHJCLEG_00484 5.3e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGHJCLEG_00485 3.2e-47 rpsJ J Involved in the binding of tRNA to the ribosomes
HGHJCLEG_00486 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGHJCLEG_00487 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HGHJCLEG_00488 4.9e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGHJCLEG_00489 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGHJCLEG_00490 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGHJCLEG_00491 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGHJCLEG_00492 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGHJCLEG_00493 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGHJCLEG_00494 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HGHJCLEG_00495 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGHJCLEG_00496 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGHJCLEG_00497 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGHJCLEG_00498 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGHJCLEG_00499 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGHJCLEG_00500 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGHJCLEG_00501 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGHJCLEG_00502 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGHJCLEG_00503 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGHJCLEG_00504 2.9e-24 rpmD J Ribosomal protein L30
HGHJCLEG_00505 1.3e-62 rplO J Binds to the 23S rRNA
HGHJCLEG_00506 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGHJCLEG_00507 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGHJCLEG_00508 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGHJCLEG_00509 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HGHJCLEG_00510 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGHJCLEG_00511 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGHJCLEG_00512 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHJCLEG_00513 1.1e-62 rplQ J Ribosomal protein L17
HGHJCLEG_00514 3.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHJCLEG_00515 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHJCLEG_00516 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHJCLEG_00517 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGHJCLEG_00518 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGHJCLEG_00519 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HGHJCLEG_00520 8e-140 IQ reductase
HGHJCLEG_00521 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
HGHJCLEG_00522 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGHJCLEG_00523 1.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGHJCLEG_00524 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HGHJCLEG_00525 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGHJCLEG_00526 1.8e-201 camS S sex pheromone
HGHJCLEG_00527 5.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGHJCLEG_00528 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGHJCLEG_00529 9.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGHJCLEG_00530 8.7e-187 yegS 2.7.1.107 G Lipid kinase
HGHJCLEG_00531 4.5e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGHJCLEG_00533 3.8e-197 L Recombinase
HGHJCLEG_00534 1.2e-14 S Recombinase
HGHJCLEG_00535 7.7e-118 L Recombinase zinc beta ribbon domain
HGHJCLEG_00537 4.5e-52 S Bacteriophage holin family
HGHJCLEG_00538 1.9e-46 S Phage head-tail joining protein
HGHJCLEG_00539 2.2e-31 S Phage gp6-like head-tail connector protein
HGHJCLEG_00540 7.1e-172 S Phage capsid family
HGHJCLEG_00541 1e-71 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HGHJCLEG_00542 1.3e-216 S Phage portal protein
HGHJCLEG_00543 2.8e-11 K Antidote-toxin recognition MazE, bacterial antitoxin
HGHJCLEG_00546 1.5e-289 S overlaps another CDS with the same product name
HGHJCLEG_00547 1.1e-24 S Domain of unknown function (DUF5049)
HGHJCLEG_00548 6e-53 S Psort location Cytoplasmic, score
HGHJCLEG_00549 4.4e-201 2.1.1.72 KL DNA methylase
HGHJCLEG_00550 5.7e-92
HGHJCLEG_00551 2.7e-72 V HNH nucleases
HGHJCLEG_00552 1.6e-82
HGHJCLEG_00553 1.1e-253 L SNF2 family N-terminal domain
HGHJCLEG_00554 2.1e-45 S VRR_NUC
HGHJCLEG_00555 0.0 S Phage plasmid primase, P4
HGHJCLEG_00556 2.5e-70 S Psort location Cytoplasmic, score
HGHJCLEG_00557 0.0 polA_2 2.7.7.7 L DNA polymerase
HGHJCLEG_00558 9.5e-95 S Protein of unknown function (DUF2815)
HGHJCLEG_00559 9.1e-201 L Protein of unknown function (DUF2800)
HGHJCLEG_00560 1.6e-28
HGHJCLEG_00561 1.1e-22
HGHJCLEG_00563 7.2e-16 S Domain of unknown function (DUF1837)
HGHJCLEG_00564 6.7e-122 F helicase superfamily c-terminal domain
HGHJCLEG_00565 3.9e-23 K Cro/C1-type HTH DNA-binding domain
HGHJCLEG_00566 2.2e-290 2.1.1.72 V type I restriction-modification system
HGHJCLEG_00567 6.4e-32 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HGHJCLEG_00568 5.2e-39 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HGHJCLEG_00569 1.9e-175 xerC L Belongs to the 'phage' integrase family
HGHJCLEG_00570 4.2e-52 3.1.21.3 V Type I restriction
HGHJCLEG_00571 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HGHJCLEG_00573 1.7e-37 S Protein of unknown function (DUF3021)
HGHJCLEG_00574 2.2e-65 K LytTr DNA-binding domain
HGHJCLEG_00575 3e-124 cylB V ABC-2 type transporter
HGHJCLEG_00576 1.7e-127 cylA V ABC transporter
HGHJCLEG_00577 9.1e-284 L Recombinase
HGHJCLEG_00578 2.1e-283 L Recombinase zinc beta ribbon domain
HGHJCLEG_00579 4.7e-27
HGHJCLEG_00580 3.8e-69 M Glycosyl hydrolases family 25
HGHJCLEG_00581 1.2e-20 M Glycosyl hydrolases family 25
HGHJCLEG_00582 3.6e-70 S Bacteriophage holin family
HGHJCLEG_00583 6.9e-68 S Phage head-tail joining protein
HGHJCLEG_00584 4.3e-43 S Phage gp6-like head-tail connector protein
HGHJCLEG_00585 2.8e-221 S Phage capsid family
HGHJCLEG_00586 1.4e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HGHJCLEG_00587 6.3e-243 S Phage portal protein
HGHJCLEG_00588 3e-306 S overlaps another CDS with the same product name
HGHJCLEG_00589 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGHJCLEG_00590 8e-122 radC L DNA repair protein
HGHJCLEG_00591 1.7e-179 mreB D cell shape determining protein MreB
HGHJCLEG_00592 3.5e-152 mreC M Involved in formation and maintenance of cell shape
HGHJCLEG_00593 8.7e-93 mreD M rod shape-determining protein MreD
HGHJCLEG_00594 3.2e-102 glnP P ABC transporter permease
HGHJCLEG_00595 4.7e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHJCLEG_00596 1.9e-158 aatB ET ABC transporter substrate-binding protein
HGHJCLEG_00597 8.1e-227 ymfF S Peptidase M16 inactive domain protein
HGHJCLEG_00598 2.5e-247 ymfH S Peptidase M16
HGHJCLEG_00599 1.7e-137 ymfM S Helix-turn-helix domain
HGHJCLEG_00600 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGHJCLEG_00601 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
HGHJCLEG_00602 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGHJCLEG_00603 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HGHJCLEG_00604 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGHJCLEG_00605 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGHJCLEG_00606 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGHJCLEG_00607 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGHJCLEG_00608 2.2e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGHJCLEG_00609 6.2e-31 yajC U Preprotein translocase
HGHJCLEG_00610 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HGHJCLEG_00611 1.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGHJCLEG_00612 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGHJCLEG_00613 4.1e-43 yrzL S Belongs to the UPF0297 family
HGHJCLEG_00614 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGHJCLEG_00615 6.1e-48 yrzB S Belongs to the UPF0473 family
HGHJCLEG_00616 1.6e-86 cvpA S Colicin V production protein
HGHJCLEG_00617 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGHJCLEG_00618 6.1e-54 trxA O Belongs to the thioredoxin family
HGHJCLEG_00619 1.6e-97 yslB S Protein of unknown function (DUF2507)
HGHJCLEG_00620 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HGHJCLEG_00621 9.8e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGHJCLEG_00622 3.8e-93 S Phosphoesterase
HGHJCLEG_00623 1.1e-74 ykuL S (CBS) domain
HGHJCLEG_00624 1.8e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HGHJCLEG_00625 6.9e-148 ykuT M mechanosensitive ion channel
HGHJCLEG_00626 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGHJCLEG_00627 4.3e-16
HGHJCLEG_00628 1.1e-195 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HGHJCLEG_00629 7.1e-181 ccpA K catabolite control protein A
HGHJCLEG_00630 1e-132
HGHJCLEG_00631 5.9e-132 yebC K Transcriptional regulatory protein
HGHJCLEG_00632 1.3e-182 comGA NU Type II IV secretion system protein
HGHJCLEG_00633 3e-182 comGB NU type II secretion system
HGHJCLEG_00634 7.1e-47 comGC U competence protein ComGC
HGHJCLEG_00635 4.1e-77 NU general secretion pathway protein
HGHJCLEG_00636 3.2e-41
HGHJCLEG_00637 1e-67
HGHJCLEG_00639 8e-224 aadAT EK Aminotransferase, class I
HGHJCLEG_00640 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGHJCLEG_00641 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGHJCLEG_00642 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HGHJCLEG_00643 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGHJCLEG_00644 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGHJCLEG_00645 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGHJCLEG_00646 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGHJCLEG_00647 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHJCLEG_00648 1.1e-204 yacL S domain protein
HGHJCLEG_00649 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGHJCLEG_00650 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HGHJCLEG_00651 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
HGHJCLEG_00652 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HGHJCLEG_00653 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
HGHJCLEG_00654 6.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HGHJCLEG_00655 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHJCLEG_00656 1.1e-119 tcyB E ABC transporter
HGHJCLEG_00657 2.5e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGHJCLEG_00658 1.3e-167 I alpha/beta hydrolase fold
HGHJCLEG_00659 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGHJCLEG_00660 0.0 S Bacterial membrane protein, YfhO
HGHJCLEG_00661 1.7e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HGHJCLEG_00662 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HGHJCLEG_00663 1e-154 S Hydrolases of the alpha beta superfamily
HGHJCLEG_00664 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HGHJCLEG_00665 4.4e-77 ctsR K Belongs to the CtsR family
HGHJCLEG_00666 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HGHJCLEG_00667 1e-110 K Bacterial regulatory proteins, tetR family
HGHJCLEG_00668 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHJCLEG_00669 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHJCLEG_00670 2.3e-199 ykiI
HGHJCLEG_00671 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HGHJCLEG_00672 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGHJCLEG_00673 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGHJCLEG_00674 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGHJCLEG_00675 4.8e-65 L Transposase
HGHJCLEG_00676 9.7e-123 L Transposase
HGHJCLEG_00677 2.8e-232 L transposase IS116 IS110 IS902 family protein
HGHJCLEG_00678 1.9e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGHJCLEG_00679 2.7e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGHJCLEG_00680 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HGHJCLEG_00681 9.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGHJCLEG_00682 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGHJCLEG_00683 1.8e-134
HGHJCLEG_00684 1.2e-145 rfbJ M Glycosyl transferase family 2
HGHJCLEG_00685 5.8e-83
HGHJCLEG_00686 2.6e-72 S Acyltransferase family
HGHJCLEG_00687 1.3e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HGHJCLEG_00688 1.8e-67 S Glycosyltransferase like family
HGHJCLEG_00689 3.4e-76 rgpB GT2 M Glycosyl transferase family 2
HGHJCLEG_00690 3.9e-28 M biosynthesis protein
HGHJCLEG_00691 3.1e-90 cps3F
HGHJCLEG_00692 4.7e-76 M transferase activity, transferring glycosyl groups
HGHJCLEG_00693 3.2e-211 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HGHJCLEG_00694 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
HGHJCLEG_00695 6.1e-25
HGHJCLEG_00696 1.5e-183 G Peptidase_C39 like family
HGHJCLEG_00697 3.3e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGHJCLEG_00698 1.3e-97
HGHJCLEG_00700 1.3e-122 yciB M ErfK YbiS YcfS YnhG
HGHJCLEG_00701 1.2e-260 S Putative peptidoglycan binding domain
HGHJCLEG_00702 3.9e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HGHJCLEG_00703 1.6e-67
HGHJCLEG_00704 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HGHJCLEG_00705 8.9e-215 yttB EGP Major facilitator Superfamily
HGHJCLEG_00706 2.6e-101
HGHJCLEG_00707 1e-24
HGHJCLEG_00708 2.5e-172 scrR K Transcriptional regulator, LacI family
HGHJCLEG_00709 2.9e-235 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGHJCLEG_00710 9.2e-50 czrA K Transcriptional regulator, ArsR family
HGHJCLEG_00711 2.5e-36
HGHJCLEG_00712 0.0 yhcA V ABC transporter, ATP-binding protein
HGHJCLEG_00713 5e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HGHJCLEG_00714 4e-166 hrtB V ABC transporter permease
HGHJCLEG_00715 1.8e-84 ygfC K transcriptional regulator (TetR family)
HGHJCLEG_00716 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HGHJCLEG_00717 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
HGHJCLEG_00718 2.9e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGHJCLEG_00719 7.4e-142 epsB M biosynthesis protein
HGHJCLEG_00720 4.1e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HGHJCLEG_00721 4e-138 cps2D 5.1.3.2 M RmlD substrate binding domain
HGHJCLEG_00722 3.8e-90 tuaA M Bacterial sugar transferase
HGHJCLEG_00723 3.5e-42 tuaG GT2 M Glycosyltransferase like family 2
HGHJCLEG_00724 3.2e-44 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
HGHJCLEG_00725 5.5e-51 waaB GT4 M Glycosyl transferases group 1
HGHJCLEG_00726 1.3e-35 M Glycosyltransferase, group 2 family protein
HGHJCLEG_00727 9.7e-58 M Glycosyltransferase like family 2
HGHJCLEG_00729 6.8e-108 S Polysaccharide biosynthesis protein
HGHJCLEG_00730 4e-45 MA20_17390 GT4 M Glycosyl transferases group 1
HGHJCLEG_00731 5.7e-81 tagB 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGHJCLEG_00732 3.5e-83 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HGHJCLEG_00733 3e-97 4.1.1.35 M Male sterility protein
HGHJCLEG_00734 7.8e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGHJCLEG_00735 2.7e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGHJCLEG_00736 5.1e-165 L Integrase core domain
HGHJCLEG_00737 1.4e-57 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGHJCLEG_00740 1.5e-121 K response regulator
HGHJCLEG_00741 4.1e-278 arlS 2.7.13.3 T Histidine kinase
HGHJCLEG_00742 7.4e-267 yjeM E Amino Acid
HGHJCLEG_00743 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HGHJCLEG_00744 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HGHJCLEG_00745 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGHJCLEG_00746 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGHJCLEG_00747 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGHJCLEG_00748 7.1e-164 S Tetratricopeptide repeat
HGHJCLEG_00749 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGHJCLEG_00750 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGHJCLEG_00751 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HGHJCLEG_00752 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
HGHJCLEG_00753 0.0 comEC S Competence protein ComEC
HGHJCLEG_00754 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
HGHJCLEG_00755 5.8e-80 comEA L Competence protein ComEA
HGHJCLEG_00756 1.9e-197 ylbL T Belongs to the peptidase S16 family
HGHJCLEG_00757 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGHJCLEG_00758 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HGHJCLEG_00759 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HGHJCLEG_00760 7.7e-222 ftsW D Belongs to the SEDS family
HGHJCLEG_00761 8.2e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGHJCLEG_00762 0.0 yfmR S ABC transporter, ATP-binding protein
HGHJCLEG_00763 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGHJCLEG_00764 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGHJCLEG_00765 1.9e-110 hlyIII S protein, hemolysin III
HGHJCLEG_00766 4.9e-151 DegV S EDD domain protein, DegV family
HGHJCLEG_00767 2.4e-167 ypmR E lipolytic protein G-D-S-L family
HGHJCLEG_00768 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HGHJCLEG_00769 4.4e-35 yozE S Belongs to the UPF0346 family
HGHJCLEG_00770 5.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGHJCLEG_00771 5.1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGHJCLEG_00772 2.1e-160 dprA LU DNA protecting protein DprA
HGHJCLEG_00773 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGHJCLEG_00774 2.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
HGHJCLEG_00775 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGHJCLEG_00776 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGHJCLEG_00777 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGHJCLEG_00778 8.1e-79 F NUDIX domain
HGHJCLEG_00779 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HGHJCLEG_00780 4.3e-107 yvyE 3.4.13.9 S YigZ family
HGHJCLEG_00781 1.6e-249 comFA L Helicase C-terminal domain protein
HGHJCLEG_00782 1.1e-93 comFC S Competence protein
HGHJCLEG_00783 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGHJCLEG_00784 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGHJCLEG_00785 1.1e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGHJCLEG_00786 7.7e-31 KT PspC domain protein
HGHJCLEG_00787 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HGHJCLEG_00788 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGHJCLEG_00789 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGHJCLEG_00790 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HGHJCLEG_00791 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGHJCLEG_00792 1e-136 yrjD S LUD domain
HGHJCLEG_00793 3e-292 lutB C 4Fe-4S dicluster domain
HGHJCLEG_00794 7.8e-168 lutA C Cysteine-rich domain
HGHJCLEG_00795 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGHJCLEG_00796 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HGHJCLEG_00797 1.4e-161 aatB ET PFAM extracellular solute-binding protein, family 3
HGHJCLEG_00798 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
HGHJCLEG_00799 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HGHJCLEG_00800 3e-52 L transposase, IS605 OrfB family
HGHJCLEG_00801 0.0 lacS G Transporter
HGHJCLEG_00802 2.3e-28
HGHJCLEG_00803 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGHJCLEG_00804 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGHJCLEG_00805 4.4e-190 yeaN P Transporter, major facilitator family protein
HGHJCLEG_00806 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
HGHJCLEG_00807 2.7e-82 nrdI F Belongs to the NrdI family
HGHJCLEG_00808 1.6e-236 yhdP S Transporter associated domain
HGHJCLEG_00809 1.4e-153 ypdB V (ABC) transporter
HGHJCLEG_00810 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
HGHJCLEG_00811 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
HGHJCLEG_00812 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
HGHJCLEG_00813 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
HGHJCLEG_00814 2.6e-160 S AI-2E family transporter
HGHJCLEG_00815 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HGHJCLEG_00816 2.2e-160
HGHJCLEG_00817 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HGHJCLEG_00818 3.6e-138 eutJ E Hsp70 protein
HGHJCLEG_00819 8.3e-159 K helix_turn_helix, arabinose operon control protein
HGHJCLEG_00820 1.6e-37 pduA_4 CQ BMC
HGHJCLEG_00821 2.7e-134 pduB E BMC
HGHJCLEG_00822 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HGHJCLEG_00823 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HGHJCLEG_00824 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
HGHJCLEG_00825 9.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
HGHJCLEG_00826 2.6e-45 pduH S Dehydratase medium subunit
HGHJCLEG_00827 1.8e-56 pduK CQ BMC
HGHJCLEG_00828 7.8e-40 pduA_4 CQ BMC
HGHJCLEG_00829 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HGHJCLEG_00830 1.3e-79 S Putative propanediol utilisation
HGHJCLEG_00831 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HGHJCLEG_00832 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HGHJCLEG_00833 4.5e-77 pduO S Haem-degrading
HGHJCLEG_00834 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HGHJCLEG_00835 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
HGHJCLEG_00836 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGHJCLEG_00837 1.1e-53 pduU E BMC
HGHJCLEG_00838 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
HGHJCLEG_00839 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
HGHJCLEG_00840 5.9e-68 P Cadmium resistance transporter
HGHJCLEG_00841 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
HGHJCLEG_00842 2.2e-73 fld C Flavodoxin
HGHJCLEG_00843 2.7e-117 XK27_04590 S NADPH-dependent FMN reductase
HGHJCLEG_00844 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
HGHJCLEG_00845 1.8e-169 cobD 4.1.1.81 E Aminotransferase class I and II
HGHJCLEG_00846 8.1e-204 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HGHJCLEG_00847 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HGHJCLEG_00848 2.5e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
HGHJCLEG_00849 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HGHJCLEG_00850 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHJCLEG_00851 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HGHJCLEG_00852 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHJCLEG_00853 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
HGHJCLEG_00854 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHJCLEG_00855 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
HGHJCLEG_00856 4.6e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHJCLEG_00857 1.8e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
HGHJCLEG_00858 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHJCLEG_00859 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HGHJCLEG_00860 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HGHJCLEG_00861 6.8e-103 cbiQ P Cobalt transport protein
HGHJCLEG_00862 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
HGHJCLEG_00863 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HGHJCLEG_00864 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
HGHJCLEG_00865 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HGHJCLEG_00866 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HGHJCLEG_00867 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
HGHJCLEG_00868 3.9e-240 hemL 5.4.3.8 H Aminotransferase class-III
HGHJCLEG_00869 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
HGHJCLEG_00870 4.9e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HGHJCLEG_00871 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
HGHJCLEG_00872 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HGHJCLEG_00873 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HGHJCLEG_00874 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HGHJCLEG_00875 2.5e-127 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HGHJCLEG_00876 2.7e-24 K helix_turn_helix, arabinose operon control protein
HGHJCLEG_00877 1.3e-186 thrC 4.2.3.1 E Threonine synthase
HGHJCLEG_00878 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HGHJCLEG_00879 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HGHJCLEG_00880 4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGHJCLEG_00881 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGHJCLEG_00882 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGHJCLEG_00883 4.4e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HGHJCLEG_00884 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHJCLEG_00885 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHJCLEG_00886 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHJCLEG_00887 5.8e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGHJCLEG_00888 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HGHJCLEG_00889 3.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGHJCLEG_00890 1e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HGHJCLEG_00891 1.6e-243 purD 6.3.4.13 F Belongs to the GARS family
HGHJCLEG_00892 1.2e-24
HGHJCLEG_00893 1.3e-146
HGHJCLEG_00894 1.3e-28
HGHJCLEG_00895 1.7e-151 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HGHJCLEG_00896 3.1e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGHJCLEG_00897 3.1e-101 fic D Fic/DOC family
HGHJCLEG_00898 7.3e-71
HGHJCLEG_00899 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HGHJCLEG_00900 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HGHJCLEG_00901 4.9e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGHJCLEG_00902 5.9e-143 ywqE 3.1.3.48 GM PHP domain protein
HGHJCLEG_00903 0.0 snf 2.7.11.1 KL domain protein
HGHJCLEG_00904 1.5e-06 D nuclear chromosome segregation
HGHJCLEG_00905 2e-36
HGHJCLEG_00906 1.2e-22 T Toxin-antitoxin system, toxin component, MazF family
HGHJCLEG_00907 1.2e-102 pncA Q Isochorismatase family
HGHJCLEG_00908 6.6e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGHJCLEG_00909 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
HGHJCLEG_00910 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGHJCLEG_00911 8.8e-172 S Phage capsid family
HGHJCLEG_00912 1.3e-39 S Phage gp6-like head-tail connector protein
HGHJCLEG_00913 7.2e-54 S Phage head-tail joining protein
HGHJCLEG_00914 2.4e-29 S Bacteriophage holin family
HGHJCLEG_00915 8.2e-19
HGHJCLEG_00916 1.3e-68 L Recombinase zinc beta ribbon domain
HGHJCLEG_00917 4.7e-19 L Recombinase zinc beta ribbon domain
HGHJCLEG_00918 1.7e-21 L recombinase activity
HGHJCLEG_00919 7.6e-67 L Recombinase
HGHJCLEG_00920 1.5e-69 L Recombinase
HGHJCLEG_00921 2e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
HGHJCLEG_00922 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
HGHJCLEG_00923 6.3e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
HGHJCLEG_00924 5.2e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HGHJCLEG_00925 1.2e-94 dps P Belongs to the Dps family
HGHJCLEG_00926 7.9e-35 copZ C Heavy-metal-associated domain
HGHJCLEG_00927 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HGHJCLEG_00928 2e-163 L PFAM Integrase catalytic region
HGHJCLEG_00929 1.8e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHJCLEG_00931 4.9e-207 L helicase activity
HGHJCLEG_00932 1e-120 L helicase activity
HGHJCLEG_00933 3.3e-71 K DNA binding
HGHJCLEG_00934 1e-88 L Recombinase
HGHJCLEG_00935 9e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HGHJCLEG_00936 1.5e-275 lysP E amino acid
HGHJCLEG_00937 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
HGHJCLEG_00938 9.8e-118 lssY 3.6.1.27 I phosphatase
HGHJCLEG_00939 1.4e-81 S Threonine/Serine exporter, ThrE
HGHJCLEG_00940 2e-127 thrE S Putative threonine/serine exporter
HGHJCLEG_00941 1e-30 cspC K Cold shock protein
HGHJCLEG_00942 1.6e-123 sirR K iron dependent repressor
HGHJCLEG_00943 5.5e-164 czcD P cation diffusion facilitator family transporter
HGHJCLEG_00944 2.5e-116 S membrane
HGHJCLEG_00945 6.4e-109 S VIT family
HGHJCLEG_00946 5.5e-83 usp1 T Belongs to the universal stress protein A family
HGHJCLEG_00947 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHJCLEG_00948 2.8e-151 glnH ET ABC transporter
HGHJCLEG_00949 2.4e-110 gluC P ABC transporter permease
HGHJCLEG_00950 3.6e-109 glnP P ABC transporter permease
HGHJCLEG_00951 8.3e-221 S CAAX protease self-immunity
HGHJCLEG_00952 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGHJCLEG_00953 7.9e-55
HGHJCLEG_00954 9.8e-74 merR K MerR HTH family regulatory protein
HGHJCLEG_00955 3.6e-269 lmrB EGP Major facilitator Superfamily
HGHJCLEG_00956 2.9e-123 S Domain of unknown function (DUF4811)
HGHJCLEG_00957 1.8e-30 S Domain of unknown function (DUF5049)
HGHJCLEG_00958 3.3e-112 S Psort location Cytoplasmic, score
HGHJCLEG_00959 2.9e-229 2.1.1.72 KL DNA methylase
HGHJCLEG_00960 3.1e-98
HGHJCLEG_00961 8.9e-86
HGHJCLEG_00962 3.8e-254 L SNF2 family N-terminal domain
HGHJCLEG_00963 7.1e-46 S VRR_NUC
HGHJCLEG_00964 0.0 S Phage plasmid primase, P4
HGHJCLEG_00965 2.8e-69 S Psort location Cytoplasmic, score
HGHJCLEG_00966 0.0 polA_2 2.7.7.7 L DNA polymerase
HGHJCLEG_00967 1.4e-98 S Protein of unknown function (DUF2815)
HGHJCLEG_00968 4e-212 L Protein of unknown function (DUF2800)
HGHJCLEG_00969 2e-41
HGHJCLEG_00970 8.5e-25
HGHJCLEG_00971 6.5e-73 K DNA-templated transcription, initiation
HGHJCLEG_00972 1.5e-18 S Domain of unknown function (DUF1837)
HGHJCLEG_00973 8.9e-135 F helicase superfamily c-terminal domain
HGHJCLEG_00974 4.9e-23 K Cro/C1-type HTH DNA-binding domain
HGHJCLEG_00975 2.3e-72 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HGHJCLEG_00976 3.7e-205 amtB P ammonium transporter
HGHJCLEG_00977 6.8e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HGHJCLEG_00978 1.9e-83 yvbK 3.1.3.25 K GNAT family
HGHJCLEG_00979 1.7e-91
HGHJCLEG_00980 1.4e-65 pnb C nitroreductase
HGHJCLEG_00981 2.6e-29 pnb C nitroreductase
HGHJCLEG_00982 2.4e-75 ogt 2.1.1.63 L Methyltransferase
HGHJCLEG_00983 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HGHJCLEG_00984 6.8e-67 S Protein of unknown function (DUF3021)
HGHJCLEG_00985 6e-76 K LytTr DNA-binding domain
HGHJCLEG_00986 1.1e-92 K Acetyltransferase (GNAT) family
HGHJCLEG_00987 1.1e-116 ybhL S Belongs to the BI1 family
HGHJCLEG_00988 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HGHJCLEG_00989 3e-195 S Protein of unknown function (DUF3114)
HGHJCLEG_00990 2.2e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGHJCLEG_00991 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGHJCLEG_00992 1.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
HGHJCLEG_00993 9.1e-62 S Domain of unknown function (DUF4828)
HGHJCLEG_00994 5.9e-191 mocA S Oxidoreductase
HGHJCLEG_00995 1.9e-231 yfmL L DEAD DEAH box helicase
HGHJCLEG_00997 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGHJCLEG_00998 6.1e-55
HGHJCLEG_00999 6e-263 argH 4.3.2.1 E argininosuccinate lyase
HGHJCLEG_01000 3.8e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGHJCLEG_01001 3.7e-96 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGHJCLEG_01002 7.8e-73 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGHJCLEG_01003 8.6e-70 yqeY S YqeY-like protein
HGHJCLEG_01004 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HGHJCLEG_01005 1.1e-262 glnPH2 P ABC transporter permease
HGHJCLEG_01006 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHJCLEG_01007 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HGHJCLEG_01008 4.6e-165 yniA G Phosphotransferase enzyme family
HGHJCLEG_01009 1.9e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGHJCLEG_01010 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGHJCLEG_01011 9.4e-50
HGHJCLEG_01012 9.7e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGHJCLEG_01013 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
HGHJCLEG_01014 7.5e-58
HGHJCLEG_01015 1.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHJCLEG_01017 6.2e-146 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HGHJCLEG_01022 4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HGHJCLEG_01024 1.3e-218 S cog cog1373
HGHJCLEG_01025 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HGHJCLEG_01026 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGHJCLEG_01027 6.2e-157 EG EamA-like transporter family
HGHJCLEG_01028 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
HGHJCLEG_01029 0.0 helD 3.6.4.12 L DNA helicase
HGHJCLEG_01030 2.8e-114 dedA S SNARE associated Golgi protein
HGHJCLEG_01031 5e-127 3.1.3.73 G phosphoglycerate mutase
HGHJCLEG_01032 8.6e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGHJCLEG_01033 6.6e-35 S Transglycosylase associated protein
HGHJCLEG_01035 2.1e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHJCLEG_01036 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
HGHJCLEG_01037 4.4e-76 S PAS domain
HGHJCLEG_01038 2.3e-87 K Acetyltransferase (GNAT) domain
HGHJCLEG_01039 2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HGHJCLEG_01040 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HGHJCLEG_01041 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGHJCLEG_01042 1.4e-104 yxjI
HGHJCLEG_01043 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HGHJCLEG_01044 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGHJCLEG_01045 5.9e-143 est 3.1.1.1 S Serine aminopeptidase, S33
HGHJCLEG_01046 1.8e-34 secG U Preprotein translocase
HGHJCLEG_01047 3.1e-292 clcA P chloride
HGHJCLEG_01048 1.2e-244 yifK E Amino acid permease
HGHJCLEG_01049 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGHJCLEG_01050 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGHJCLEG_01051 1.7e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HGHJCLEG_01052 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGHJCLEG_01054 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGHJCLEG_01055 6.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HGHJCLEG_01056 7.1e-63
HGHJCLEG_01057 4e-14
HGHJCLEG_01058 5.8e-59
HGHJCLEG_01059 1.8e-38
HGHJCLEG_01060 1.1e-134 V ABC transporter
HGHJCLEG_01061 2.6e-211 EGP Major facilitator Superfamily
HGHJCLEG_01062 7.2e-256 G PTS system Galactitol-specific IIC component
HGHJCLEG_01063 9.8e-23 1.6.5.5 C Zinc-binding dehydrogenase
HGHJCLEG_01064 2e-86 1.6.5.5 C Zinc-binding dehydrogenase
HGHJCLEG_01065 1e-159
HGHJCLEG_01066 1e-72 K Transcriptional regulator
HGHJCLEG_01067 2e-172 D Alpha beta
HGHJCLEG_01068 6.4e-52 ypaA S Protein of unknown function (DUF1304)
HGHJCLEG_01069 0.0 yjcE P Sodium proton antiporter
HGHJCLEG_01070 1.6e-52 yvlA
HGHJCLEG_01071 6.6e-111 P Cobalt transport protein
HGHJCLEG_01072 4.9e-249 cbiO1 S ABC transporter, ATP-binding protein
HGHJCLEG_01073 1.3e-96 S ABC-type cobalt transport system, permease component
HGHJCLEG_01074 9.6e-133 S membrane transporter protein
HGHJCLEG_01075 1.2e-112 IQ KR domain
HGHJCLEG_01076 2e-09 IQ KR domain
HGHJCLEG_01077 1.6e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHJCLEG_01078 5.4e-48 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGHJCLEG_01079 3.7e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HGHJCLEG_01080 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGHJCLEG_01081 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGHJCLEG_01082 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGHJCLEG_01083 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGHJCLEG_01084 2.4e-251 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGHJCLEG_01085 9.8e-67 yabR J RNA binding
HGHJCLEG_01086 8.1e-55 divIC D Septum formation initiator
HGHJCLEG_01087 6.2e-39 yabO J S4 domain protein
HGHJCLEG_01088 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGHJCLEG_01089 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGHJCLEG_01090 6.9e-113 S (CBS) domain
HGHJCLEG_01091 6.4e-145 tesE Q hydratase
HGHJCLEG_01092 2.3e-242 codA 3.5.4.1 F cytosine deaminase
HGHJCLEG_01093 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HGHJCLEG_01094 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HGHJCLEG_01095 3.4e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGHJCLEG_01096 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGHJCLEG_01098 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGHJCLEG_01099 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HGHJCLEG_01100 1.1e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGHJCLEG_01101 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGHJCLEG_01102 4.9e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
HGHJCLEG_01103 1.5e-152 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGHJCLEG_01104 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGHJCLEG_01105 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGHJCLEG_01106 7.5e-158 htpX O Belongs to the peptidase M48B family
HGHJCLEG_01107 7e-93 lemA S LemA family
HGHJCLEG_01108 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHJCLEG_01109 2.7e-120 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HGHJCLEG_01110 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HGHJCLEG_01111 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGHJCLEG_01112 8.8e-158 3.2.1.55 GH51 G Right handed beta helix region
HGHJCLEG_01113 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HGHJCLEG_01114 7.3e-116 srtA 3.4.22.70 M sortase family
HGHJCLEG_01115 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HGHJCLEG_01116 5.4e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHJCLEG_01117 4.6e-41 rpmE2 J Ribosomal protein L31
HGHJCLEG_01118 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGHJCLEG_01119 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGHJCLEG_01120 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGHJCLEG_01121 5.2e-53 ywiB S Domain of unknown function (DUF1934)
HGHJCLEG_01122 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
HGHJCLEG_01123 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HGHJCLEG_01124 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HGHJCLEG_01125 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HGHJCLEG_01126 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
HGHJCLEG_01127 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGHJCLEG_01128 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGHJCLEG_01129 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HGHJCLEG_01130 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGHJCLEG_01131 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGHJCLEG_01132 2e-115 yoaK S Protein of unknown function (DUF1275)
HGHJCLEG_01133 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGHJCLEG_01134 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGHJCLEG_01135 1.7e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGHJCLEG_01136 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGHJCLEG_01137 5.9e-223 dnaB L replication initiation and membrane attachment
HGHJCLEG_01138 1.9e-172 dnaI L Primosomal protein DnaI
HGHJCLEG_01139 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGHJCLEG_01140 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HGHJCLEG_01141 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGHJCLEG_01142 2.4e-95 yqeG S HAD phosphatase, family IIIA
HGHJCLEG_01143 4.8e-218 yqeH S Ribosome biogenesis GTPase YqeH
HGHJCLEG_01144 1.9e-47 yhbY J RNA-binding protein
HGHJCLEG_01145 4.5e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGHJCLEG_01146 6.2e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HGHJCLEG_01147 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGHJCLEG_01148 9.7e-135 yqeM Q Methyltransferase
HGHJCLEG_01149 5.3e-209 ylbM S Belongs to the UPF0348 family
HGHJCLEG_01150 4.9e-99 yceD S Uncharacterized ACR, COG1399
HGHJCLEG_01151 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HGHJCLEG_01152 5e-158 M domain protein
HGHJCLEG_01153 1.9e-306 M domain protein
HGHJCLEG_01154 2e-91
HGHJCLEG_01156 3.3e-78 yjcE P Sodium proton antiporter
HGHJCLEG_01157 1.1e-149 yjcE P Sodium proton antiporter
HGHJCLEG_01158 2.3e-56
HGHJCLEG_01160 1.2e-85
HGHJCLEG_01161 0.0 copA 3.6.3.54 P P-type ATPase
HGHJCLEG_01162 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HGHJCLEG_01163 2.9e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HGHJCLEG_01164 4.5e-158 EG EamA-like transporter family
HGHJCLEG_01165 3.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HGHJCLEG_01166 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGHJCLEG_01167 3.6e-154 KT YcbB domain
HGHJCLEG_01168 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HGHJCLEG_01170 3.6e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGHJCLEG_01171 3.7e-123 L Transposase
HGHJCLEG_01172 3e-75 L Transposase
HGHJCLEG_01173 1.9e-43 L Transposase
HGHJCLEG_01174 3.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HGHJCLEG_01175 2.2e-203 XK27_09615 S reductase
HGHJCLEG_01176 2.4e-101 nqr 1.5.1.36 S reductase
HGHJCLEG_01178 1.7e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGHJCLEG_01179 3.8e-174 K Transcriptional regulator, LacI family
HGHJCLEG_01180 6.1e-260 G Major Facilitator
HGHJCLEG_01181 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HGHJCLEG_01182 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HGHJCLEG_01183 1.3e-67 gtcA S Teichoic acid glycosylation protein
HGHJCLEG_01184 1.4e-78 fld C Flavodoxin
HGHJCLEG_01185 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
HGHJCLEG_01186 1.6e-221 arcT 2.6.1.1 E Aminotransferase
HGHJCLEG_01187 9.5e-256 E Arginine ornithine antiporter
HGHJCLEG_01188 3.4e-280 yjeM E Amino Acid
HGHJCLEG_01189 1.8e-143 yihY S Belongs to the UPF0761 family
HGHJCLEG_01190 6.6e-34 S Protein of unknown function (DUF2922)
HGHJCLEG_01191 4.9e-31
HGHJCLEG_01192 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
HGHJCLEG_01193 1.9e-146 cps1D M Domain of unknown function (DUF4422)
HGHJCLEG_01194 2.3e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HGHJCLEG_01195 2.1e-117 rfbP 2.7.8.6 M Bacterial sugar transferase
HGHJCLEG_01196 0.0 2.7.7.6 M Peptidase family M23
HGHJCLEG_01198 2.9e-81 ydcK S Belongs to the SprT family
HGHJCLEG_01199 0.0 yhgF K Tex-like protein N-terminal domain protein
HGHJCLEG_01200 2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGHJCLEG_01201 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGHJCLEG_01202 5.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
HGHJCLEG_01203 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HGHJCLEG_01204 1e-301 aspT P Predicted Permease Membrane Region
HGHJCLEG_01205 8.5e-249 EGP Major facilitator Superfamily
HGHJCLEG_01206 8.5e-111
HGHJCLEG_01209 5.9e-149 yjjH S Calcineurin-like phosphoesterase
HGHJCLEG_01210 1.3e-263 dtpT U amino acid peptide transporter
HGHJCLEG_01214 1.2e-138 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HGHJCLEG_01215 7e-22 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HGHJCLEG_01216 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGHJCLEG_01217 4e-264 glnA 6.3.1.2 E glutamine synthetase
HGHJCLEG_01218 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGHJCLEG_01219 5.9e-22 S Protein of unknown function (DUF3042)
HGHJCLEG_01220 3.4e-67 yqhL P Rhodanese-like protein
HGHJCLEG_01221 2.1e-182 glk 2.7.1.2 G Glucokinase
HGHJCLEG_01222 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HGHJCLEG_01223 6.2e-109 gluP 3.4.21.105 S Peptidase, S54 family
HGHJCLEG_01224 6.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGHJCLEG_01225 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGHJCLEG_01226 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HGHJCLEG_01227 0.0 S membrane
HGHJCLEG_01228 1.6e-67 yneR S Belongs to the HesB IscA family
HGHJCLEG_01229 1.1e-180 yfeX P Peroxidase
HGHJCLEG_01230 2.6e-91 lsa S ABC transporter
HGHJCLEG_01231 3.8e-114 lsa S ABC transporter
HGHJCLEG_01232 3e-133 I alpha/beta hydrolase fold
HGHJCLEG_01233 4e-179 MA20_14895 S Conserved hypothetical protein 698
HGHJCLEG_01234 8.4e-85 S NADPH-dependent FMN reductase
HGHJCLEG_01235 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGHJCLEG_01236 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HGHJCLEG_01237 2e-231 mntH P H( )-stimulated, divalent metal cation uptake system
HGHJCLEG_01238 2.4e-79 Q Methyltransferase
HGHJCLEG_01239 7.7e-115 ktrA P domain protein
HGHJCLEG_01240 7.6e-239 ktrB P Potassium uptake protein
HGHJCLEG_01241 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HGHJCLEG_01242 4.6e-21
HGHJCLEG_01243 5.1e-84 yueI S Protein of unknown function (DUF1694)
HGHJCLEG_01244 7.9e-233 rarA L recombination factor protein RarA
HGHJCLEG_01245 1.7e-45
HGHJCLEG_01246 4.3e-83 usp6 T universal stress protein
HGHJCLEG_01247 1.4e-203 araR K Transcriptional regulator
HGHJCLEG_01248 7.3e-155 ytbE 1.1.1.346 S Aldo keto reductase
HGHJCLEG_01249 9.2e-29 maa 2.3.1.79 S Maltose O-acetyltransferase
HGHJCLEG_01250 2.2e-50 maa 2.3.1.79 S Maltose O-acetyltransferase
HGHJCLEG_01251 2.2e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HGHJCLEG_01252 1.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HGHJCLEG_01253 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HGHJCLEG_01254 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGHJCLEG_01255 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HGHJCLEG_01256 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HGHJCLEG_01258 2e-184 S PglZ domain
HGHJCLEG_01259 2.6e-49 doc S Fic/DOC family
HGHJCLEG_01261 2.8e-296 2.1.1.72 LV Eco57I restriction-modification methylase
HGHJCLEG_01262 1e-221 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HGHJCLEG_01263 1.7e-49 S Domain of unknown function (DUF1788)
HGHJCLEG_01264 4.4e-45 S Putative inner membrane protein (DUF1819)
HGHJCLEG_01266 9.8e-15 K Cro/C1-type HTH DNA-binding domain
HGHJCLEG_01267 6e-50 ebh D nuclear chromosome segregation
HGHJCLEG_01270 6.3e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HGHJCLEG_01271 2.2e-10 L Resolvase, N terminal domain
HGHJCLEG_01272 1.6e-76 L Resolvase, N terminal domain
HGHJCLEG_01274 2.2e-153
HGHJCLEG_01277 4e-19
HGHJCLEG_01278 2e-129 L Belongs to the 'phage' integrase family
HGHJCLEG_01279 8.7e-113 fic S Fic/DOC family
HGHJCLEG_01281 5.2e-146 L Transposase and inactivated derivatives IS30 family
HGHJCLEG_01283 6e-26
HGHJCLEG_01285 6.4e-96 V VanZ like family
HGHJCLEG_01286 1.9e-145 K LysR substrate binding domain
HGHJCLEG_01287 3.5e-175 MA20_14895 S Conserved hypothetical protein 698
HGHJCLEG_01290 1.2e-114 L PFAM Integrase catalytic region
HGHJCLEG_01291 7.3e-107 ywnB S NAD(P)H-binding
HGHJCLEG_01292 1.1e-36 S Cytochrome b5-like Heme/Steroid binding domain
HGHJCLEG_01293 1.2e-253 nhaC C Na H antiporter NhaC
HGHJCLEG_01294 1.1e-181 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGHJCLEG_01296 1.2e-97 ydeN S Serine hydrolase
HGHJCLEG_01297 1.4e-26 psiE S Phosphate-starvation-inducible E
HGHJCLEG_01298 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGHJCLEG_01300 1.8e-178 S Aldo keto reductase
HGHJCLEG_01301 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HGHJCLEG_01302 0.0 L Helicase C-terminal domain protein
HGHJCLEG_01304 8.5e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HGHJCLEG_01305 2.6e-52 S Sugar efflux transporter for intercellular exchange
HGHJCLEG_01306 2.3e-125
HGHJCLEG_01307 1.3e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HGHJCLEG_01308 2.5e-311 cadA P P-type ATPase
HGHJCLEG_01309 1.1e-220 5.4.2.7 G Metalloenzyme superfamily
HGHJCLEG_01311 1.6e-35 1.6.5.2 GM NAD(P)H-binding
HGHJCLEG_01312 1.9e-51 1.6.5.2 GM NAD(P)H-binding
HGHJCLEG_01313 8.4e-73 K Transcriptional regulator
HGHJCLEG_01314 7e-164 proX M ABC transporter, substrate-binding protein, QAT family
HGHJCLEG_01315 2.4e-108 proWZ P ABC transporter permease
HGHJCLEG_01316 6.5e-142 proV E ABC transporter, ATP-binding protein
HGHJCLEG_01317 1.9e-102 proW P ABC transporter, permease protein
HGHJCLEG_01318 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HGHJCLEG_01319 1.2e-95 clcA P chloride
HGHJCLEG_01320 1.5e-15 clcA P chloride
HGHJCLEG_01321 6.5e-75 K Copper transport repressor CopY TcrY
HGHJCLEG_01322 0.0 copB 3.6.3.4 P P-type ATPase
HGHJCLEG_01324 3.5e-12
HGHJCLEG_01326 2.2e-50
HGHJCLEG_01327 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
HGHJCLEG_01328 1.9e-185 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
HGHJCLEG_01329 3.6e-07 L Resolvase, N terminal domain
HGHJCLEG_01330 8.3e-34
HGHJCLEG_01331 5.2e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
HGHJCLEG_01334 1.2e-120 GM NmrA-like family
HGHJCLEG_01335 1.8e-50 hxlR K Transcriptional regulator, HxlR family
HGHJCLEG_01336 4.1e-107 XK27_02070 S Nitroreductase family
HGHJCLEG_01337 1.2e-82 K Transcriptional regulator, HxlR family
HGHJCLEG_01338 1.6e-233
HGHJCLEG_01339 1.4e-209 EGP Major facilitator Superfamily
HGHJCLEG_01340 3e-256 pepC 3.4.22.40 E aminopeptidase
HGHJCLEG_01341 6e-109 ylbE GM NAD dependent epimerase dehydratase family protein
HGHJCLEG_01342 0.0 pepN 3.4.11.2 E aminopeptidase
HGHJCLEG_01343 1.9e-48 K Transcriptional regulator
HGHJCLEG_01344 2.3e-24 folT S ECF transporter, substrate-specific component
HGHJCLEG_01345 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
HGHJCLEG_01346 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HGHJCLEG_01347 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HGHJCLEG_01348 6.7e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HGHJCLEG_01349 0.0 pacL 3.6.3.8 P P-type ATPase
HGHJCLEG_01350 9.9e-85 dps P Belongs to the Dps family
HGHJCLEG_01351 4.8e-177 yagE E amino acid
HGHJCLEG_01352 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HGHJCLEG_01353 2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HGHJCLEG_01354 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HGHJCLEG_01355 1.1e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HGHJCLEG_01356 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HGHJCLEG_01357 1.6e-166 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HGHJCLEG_01358 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGHJCLEG_01359 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HGHJCLEG_01360 2.6e-33 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HGHJCLEG_01361 1.1e-53 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HGHJCLEG_01362 9.6e-129 narI 1.7.5.1 C Nitrate reductase
HGHJCLEG_01363 4.2e-153 EG EamA-like transporter family
HGHJCLEG_01364 9.4e-118 L Integrase
HGHJCLEG_01365 3e-156 rssA S Phospholipase, patatin family
HGHJCLEG_01366 3.5e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HGHJCLEG_01367 2.1e-276 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HGHJCLEG_01368 2.3e-173 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGHJCLEG_01369 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGHJCLEG_01370 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGHJCLEG_01371 3.4e-48
HGHJCLEG_01373 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGHJCLEG_01374 2.4e-56 K transcriptional regulator PadR family
HGHJCLEG_01375 3.2e-83 XK27_06920 S Protein of unknown function (DUF1700)
HGHJCLEG_01376 1.3e-131 S Putative adhesin
HGHJCLEG_01377 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HGHJCLEG_01378 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGHJCLEG_01379 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGHJCLEG_01380 3.4e-35 nrdH O Glutaredoxin
HGHJCLEG_01381 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGHJCLEG_01382 2.1e-31 L Transposase IS66 family
HGHJCLEG_01383 5.4e-124 fhaB M Rib/alpha-like repeat
HGHJCLEG_01389 2.2e-07 S Domain of unknown function (DUF3173)
HGHJCLEG_01390 4.3e-87 L Belongs to the 'phage' integrase family
HGHJCLEG_01391 3e-167 murB 1.3.1.98 M Cell wall formation
HGHJCLEG_01392 6.1e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGHJCLEG_01393 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGHJCLEG_01394 3.7e-249 fucP G Major Facilitator Superfamily
HGHJCLEG_01395 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGHJCLEG_01396 1.3e-125 ybbR S YbbR-like protein
HGHJCLEG_01397 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGHJCLEG_01398 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGHJCLEG_01399 5.6e-52
HGHJCLEG_01400 0.0 oatA I Acyltransferase
HGHJCLEG_01401 1.4e-72 K Transcriptional regulator
HGHJCLEG_01403 5.5e-248 mmuP E amino acid
HGHJCLEG_01404 1.4e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HGHJCLEG_01405 1.1e-43
HGHJCLEG_01407 1.8e-09
HGHJCLEG_01408 4.8e-50 doc S Fic/DOC family
HGHJCLEG_01409 5.5e-29 S Protein of unknown function (DUF4065)
HGHJCLEG_01411 3.2e-53 YPO0284 GM NAD(P)H-binding
HGHJCLEG_01413 1.2e-100
HGHJCLEG_01414 4e-21
HGHJCLEG_01415 1.8e-184 L Transposase IS66 family
HGHJCLEG_01416 3.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HGHJCLEG_01417 0.0 M NlpC/P60 family
HGHJCLEG_01418 0.0 S Peptidase, M23
HGHJCLEG_01419 0.0 bamA GM domain, Protein
HGHJCLEG_01421 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HGHJCLEG_01422 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HGHJCLEG_01423 8.4e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGHJCLEG_01424 1.6e-255 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HGHJCLEG_01425 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGHJCLEG_01426 7.6e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGHJCLEG_01427 1.4e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGHJCLEG_01428 1.2e-124 IQ reductase
HGHJCLEG_01429 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HGHJCLEG_01430 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGHJCLEG_01431 1.8e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGHJCLEG_01432 4.7e-76 marR K Transcriptional regulator, MarR family
HGHJCLEG_01433 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGHJCLEG_01435 1.3e-201 xerS L Belongs to the 'phage' integrase family
HGHJCLEG_01437 3.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HGHJCLEG_01438 1.1e-218 EG GntP family permease
HGHJCLEG_01439 8.5e-84 KT Putative sugar diacid recognition
HGHJCLEG_01440 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGHJCLEG_01441 7.7e-219 patA 2.6.1.1 E Aminotransferase
HGHJCLEG_01442 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGHJCLEG_01443 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGHJCLEG_01444 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGHJCLEG_01445 2.4e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGHJCLEG_01446 4.1e-245 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGHJCLEG_01447 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HGHJCLEG_01448 1.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGHJCLEG_01449 5.8e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGHJCLEG_01450 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGHJCLEG_01451 1.3e-117 S Repeat protein
HGHJCLEG_01452 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HGHJCLEG_01453 5.3e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGHJCLEG_01454 7.5e-58 XK27_04120 S Putative amino acid metabolism
HGHJCLEG_01455 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
HGHJCLEG_01456 5.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGHJCLEG_01458 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HGHJCLEG_01459 4.2e-32 cspA K Cold shock protein
HGHJCLEG_01460 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGHJCLEG_01461 1e-35 divIVA D DivIVA domain protein
HGHJCLEG_01462 5.4e-144 ylmH S S4 domain protein
HGHJCLEG_01463 8.3e-41 yggT S YGGT family
HGHJCLEG_01464 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGHJCLEG_01465 7.8e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGHJCLEG_01466 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGHJCLEG_01467 7.9e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGHJCLEG_01468 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGHJCLEG_01469 1.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGHJCLEG_01470 4.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGHJCLEG_01471 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HGHJCLEG_01472 1.3e-55 ftsL D Cell division protein FtsL
HGHJCLEG_01473 1.3e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGHJCLEG_01474 3.1e-77 mraZ K Belongs to the MraZ family
HGHJCLEG_01475 1.9e-56
HGHJCLEG_01476 1.2e-10 S Protein of unknown function (DUF4044)
HGHJCLEG_01477 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HGHJCLEG_01478 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGHJCLEG_01479 1e-159 rrmA 2.1.1.187 H Methyltransferase
HGHJCLEG_01480 6.6e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HGHJCLEG_01482 5.9e-18 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
HGHJCLEG_01483 1.6e-109 T Transcriptional regulatory protein, C terminal
HGHJCLEG_01484 1.3e-214 T GHKL domain
HGHJCLEG_01485 8.7e-82 S Peptidase propeptide and YPEB domain
HGHJCLEG_01486 1.5e-65 lacA S transferase hexapeptide repeat
HGHJCLEG_01487 2.2e-119 S Alpha beta hydrolase
HGHJCLEG_01488 5.1e-153 tesE Q hydratase
HGHJCLEG_01489 6.6e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGHJCLEG_01490 2.3e-155 ypuA S Protein of unknown function (DUF1002)
HGHJCLEG_01491 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HGHJCLEG_01492 2.1e-144 K Transcriptional regulator
HGHJCLEG_01493 8.8e-15
HGHJCLEG_01495 1.5e-169 whiA K May be required for sporulation
HGHJCLEG_01496 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HGHJCLEG_01497 4.6e-160 rapZ S Displays ATPase and GTPase activities
HGHJCLEG_01498 1.6e-244 steT E amino acid
HGHJCLEG_01499 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGHJCLEG_01500 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGHJCLEG_01501 6.9e-14
HGHJCLEG_01502 1.9e-115 yfbR S HD containing hydrolase-like enzyme
HGHJCLEG_01503 2.9e-235 V MatE
HGHJCLEG_01504 1.3e-67 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HGHJCLEG_01505 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGHJCLEG_01506 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HGHJCLEG_01507 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGHJCLEG_01508 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGHJCLEG_01509 6.7e-59 yodB K Transcriptional regulator, HxlR family
HGHJCLEG_01510 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGHJCLEG_01511 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGHJCLEG_01512 5.6e-115 rlpA M PFAM NLP P60 protein
HGHJCLEG_01513 2.3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
HGHJCLEG_01514 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGHJCLEG_01515 3.4e-92 ywlG S Belongs to the UPF0340 family
HGHJCLEG_01516 2.1e-160 spoU 2.1.1.185 J Methyltransferase
HGHJCLEG_01517 2.9e-224 oxlT P Major Facilitator Superfamily
HGHJCLEG_01518 4.9e-229 L Belongs to the 'phage' integrase family
HGHJCLEG_01519 1.4e-33 S Domain of unknown function (DUF3173)
HGHJCLEG_01521 0.0
HGHJCLEG_01522 5.3e-125
HGHJCLEG_01523 9.8e-79 L Resolvase, N terminal domain
HGHJCLEG_01524 8.5e-10 L Resolvase, N terminal domain
HGHJCLEG_01525 3.7e-10 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
HGHJCLEG_01526 2.3e-08 K Transcriptional regulator, HxlR family
HGHJCLEG_01527 8.1e-35
HGHJCLEG_01528 3.2e-89
HGHJCLEG_01529 3.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGHJCLEG_01530 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HGHJCLEG_01531 7.3e-293 yjbQ P TrkA C-terminal domain protein
HGHJCLEG_01532 4.2e-272 pipD E Dipeptidase
HGHJCLEG_01533 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HGHJCLEG_01534 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
HGHJCLEG_01535 6.3e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HGHJCLEG_01536 2.7e-120 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HGHJCLEG_01537 2.2e-57
HGHJCLEG_01539 3.8e-130 mltD CBM50 M NlpC P60 family protein
HGHJCLEG_01540 1.3e-28
HGHJCLEG_01541 4.3e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HGHJCLEG_01542 9.8e-32 ykzG S Belongs to the UPF0356 family
HGHJCLEG_01543 5.3e-78
HGHJCLEG_01544 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGHJCLEG_01545 1.3e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HGHJCLEG_01546 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HGHJCLEG_01547 1.3e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGHJCLEG_01548 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
HGHJCLEG_01549 8.3e-19 S PFAM Archaeal ATPase
HGHJCLEG_01550 1.6e-178 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHJCLEG_01551 1.7e-17 K Winged helix DNA-binding domain
HGHJCLEG_01552 2.9e-299 lmrA V ABC transporter, ATP-binding protein
HGHJCLEG_01553 0.0 yfiC V ABC transporter
HGHJCLEG_01554 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HGHJCLEG_01555 5.8e-269 pipD E Dipeptidase
HGHJCLEG_01556 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGHJCLEG_01557 5.5e-29 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HGHJCLEG_01558 9.1e-49
HGHJCLEG_01559 3.4e-205 nrnB S DHHA1 domain
HGHJCLEG_01560 6.2e-227 S Uncharacterized protein conserved in bacteria (DUF2325)
HGHJCLEG_01561 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
HGHJCLEG_01562 1.1e-104 NU mannosyl-glycoprotein
HGHJCLEG_01563 5e-142 S Putative ABC-transporter type IV
HGHJCLEG_01564 7.1e-273 S ABC transporter, ATP-binding protein
HGHJCLEG_01565 6.4e-08 S HTH domain
HGHJCLEG_01566 0.0 rafA 3.2.1.22 G alpha-galactosidase
HGHJCLEG_01567 5.7e-186 galR K Periplasmic binding protein-like domain
HGHJCLEG_01568 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HGHJCLEG_01569 6.2e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHJCLEG_01570 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HGHJCLEG_01571 4e-148 f42a O Band 7 protein
HGHJCLEG_01572 2.7e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HGHJCLEG_01573 2.7e-154 yitU 3.1.3.104 S hydrolase
HGHJCLEG_01574 2.7e-38 S Cytochrome B5
HGHJCLEG_01575 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HGHJCLEG_01576 2.2e-122 fhuC P ABC transporter
HGHJCLEG_01577 4.7e-127 znuB U ABC 3 transport family
HGHJCLEG_01578 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HGHJCLEG_01579 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGHJCLEG_01580 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGHJCLEG_01581 9e-48
HGHJCLEG_01582 6.1e-146 yxeH S hydrolase
HGHJCLEG_01583 1e-270 ywfO S HD domain protein
HGHJCLEG_01584 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HGHJCLEG_01585 3.4e-74 K Transcriptional regulator, TetR family
HGHJCLEG_01586 2.1e-12 K Transcriptional regulator, TetR family
HGHJCLEG_01587 1.4e-13 steT_1 E amino acid
HGHJCLEG_01589 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGHJCLEG_01590 6.9e-83
HGHJCLEG_01591 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGHJCLEG_01592 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGHJCLEG_01593 1.7e-262 nox C NADH oxidase
HGHJCLEG_01594 3e-87 hmpT S ECF-type riboflavin transporter, S component
HGHJCLEG_01595 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HGHJCLEG_01596 5.9e-168 yvgN C Aldo keto reductase
HGHJCLEG_01597 6.6e-136 puuD S peptidase C26
HGHJCLEG_01598 1.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGHJCLEG_01599 1.4e-215 yfeO P Voltage gated chloride channel
HGHJCLEG_01600 3.1e-226 sptS 2.7.13.3 T Histidine kinase
HGHJCLEG_01601 3.3e-118 K response regulator
HGHJCLEG_01602 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
HGHJCLEG_01603 1e-71
HGHJCLEG_01604 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HGHJCLEG_01605 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HGHJCLEG_01606 1.1e-256 malT G Major Facilitator
HGHJCLEG_01607 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
HGHJCLEG_01608 4.3e-172 malR K Transcriptional regulator, LacI family
HGHJCLEG_01609 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HGHJCLEG_01610 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HGHJCLEG_01611 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGHJCLEG_01612 2e-103 wecD3 K PFAM GCN5-related N-acetyltransferase
HGHJCLEG_01614 0.0 clpL O associated with various cellular activities
HGHJCLEG_01615 7.8e-32
HGHJCLEG_01616 1.2e-214 patA 2.6.1.1 E Aminotransferase
HGHJCLEG_01617 3.2e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHJCLEG_01618 5e-75 osmC O OsmC-like protein
HGHJCLEG_01619 3.5e-174 S Domain of unknown function (DUF389)
HGHJCLEG_01620 5.3e-54 U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGHJCLEG_01621 8.1e-07
HGHJCLEG_01622 5.8e-288 S Protein of unknown function DUF262
HGHJCLEG_01623 0.0 L Type III restriction enzyme, res subunit
HGHJCLEG_01624 1.9e-86 2.1.1.72, 3.1.21.4 L site-specific DNA-methyltransferase (adenine-specific) activity
HGHJCLEG_01625 1.7e-219 V domain protein
HGHJCLEG_01626 1.7e-93 K Transcriptional regulator (TetR family)
HGHJCLEG_01627 1.7e-38 pspC KT positive regulation of macromolecule biosynthetic process
HGHJCLEG_01628 7.1e-150
HGHJCLEG_01629 4e-17 3.2.1.14 GH18
HGHJCLEG_01630 9.6e-82 zur P Belongs to the Fur family
HGHJCLEG_01631 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
HGHJCLEG_01632 4.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HGHJCLEG_01633 1e-254 yfnA E Amino Acid
HGHJCLEG_01634 5.7e-231 EGP Sugar (and other) transporter
HGHJCLEG_01635 1.3e-168 L Belongs to the 'phage' integrase family
HGHJCLEG_01636 3.1e-19 S Excisionase from transposon Tn916
HGHJCLEG_01639 3.3e-133
HGHJCLEG_01640 1.1e-12 S Helix-turn-helix domain
HGHJCLEG_01642 1e-78 L Resolvase, N terminal domain
HGHJCLEG_01644 2.9e-09 L Resolvase, N terminal domain
HGHJCLEG_01645 1.1e-13 K Transcriptional
HGHJCLEG_01646 4.5e-51 L Integrase
HGHJCLEG_01647 1e-28 WQ51_00220 K Helix-turn-helix domain
HGHJCLEG_01648 6e-98 S Protein of unknown function (DUF3278)
HGHJCLEG_01649 1.7e-73 M PFAM NLP P60 protein
HGHJCLEG_01650 4.1e-181 ABC-SBP S ABC transporter
HGHJCLEG_01651 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HGHJCLEG_01652 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
HGHJCLEG_01653 7.4e-95 P Cadmium resistance transporter
HGHJCLEG_01654 4.9e-54 K Transcriptional regulator, ArsR family
HGHJCLEG_01655 2.7e-236 mepA V MATE efflux family protein
HGHJCLEG_01656 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGHJCLEG_01657 1.9e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHJCLEG_01659 1.6e-39
HGHJCLEG_01660 5.1e-43
HGHJCLEG_01661 3.4e-211 folP 2.5.1.15 H dihydropteroate synthase
HGHJCLEG_01662 1.6e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HGHJCLEG_01663 1e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGHJCLEG_01664 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HGHJCLEG_01665 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HGHJCLEG_01666 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGHJCLEG_01667 6.4e-69
HGHJCLEG_01669 1.9e-43
HGHJCLEG_01670 3.6e-109 S CAAX protease self-immunity
HGHJCLEG_01671 1.8e-31
HGHJCLEG_01672 5.8e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HGHJCLEG_01673 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGHJCLEG_01674 6.7e-60 ydiI Q Thioesterase superfamily
HGHJCLEG_01675 7.1e-109 yvrI K sigma factor activity
HGHJCLEG_01676 9.8e-206 G Transporter, major facilitator family protein
HGHJCLEG_01677 0.0 S Bacterial membrane protein YfhO
HGHJCLEG_01678 3.3e-103 T Ion transport 2 domain protein
HGHJCLEG_01679 9.9e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HGHJCLEG_01680 8.5e-34
HGHJCLEG_01681 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
HGHJCLEG_01682 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HGHJCLEG_01683 3.8e-10
HGHJCLEG_01684 5.7e-186 lacR K Transcriptional regulator
HGHJCLEG_01685 0.0 lacS G Transporter
HGHJCLEG_01686 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HGHJCLEG_01687 9.3e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGHJCLEG_01688 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HGHJCLEG_01689 6.9e-60 asp S Asp23 family, cell envelope-related function
HGHJCLEG_01690 6.1e-25
HGHJCLEG_01691 2.6e-92
HGHJCLEG_01692 3.7e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HGHJCLEG_01693 2.1e-180 K Transcriptional regulator, LacI family
HGHJCLEG_01694 1.5e-231 gntT EG Gluconate
HGHJCLEG_01695 3e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HGHJCLEG_01696 2.9e-96 K Acetyltransferase (GNAT) domain
HGHJCLEG_01697 5.4e-20
HGHJCLEG_01698 2.4e-22
HGHJCLEG_01699 2.2e-44
HGHJCLEG_01700 7e-57 yhaI S Protein of unknown function (DUF805)
HGHJCLEG_01701 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HGHJCLEG_01702 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HGHJCLEG_01703 9.4e-38 yheA S Belongs to the UPF0342 family
HGHJCLEG_01704 1.3e-218 yhaO L Ser Thr phosphatase family protein
HGHJCLEG_01705 0.0 L AAA domain
HGHJCLEG_01706 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGHJCLEG_01707 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HGHJCLEG_01708 2.8e-31 feoA P FeoA domain
HGHJCLEG_01709 1.9e-144 sufC O FeS assembly ATPase SufC
HGHJCLEG_01710 5.1e-240 sufD O FeS assembly protein SufD
HGHJCLEG_01711 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGHJCLEG_01712 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
HGHJCLEG_01713 3.6e-271 sufB O assembly protein SufB
HGHJCLEG_01714 2.8e-57 yitW S Iron-sulfur cluster assembly protein
HGHJCLEG_01715 2.6e-158 hipB K Helix-turn-helix
HGHJCLEG_01716 5.7e-115 nreC K PFAM regulatory protein LuxR
HGHJCLEG_01717 1.5e-91 2.3.1.183 M Acetyltransferase GNAT family
HGHJCLEG_01718 2.2e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HGHJCLEG_01719 3.2e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HGHJCLEG_01720 5.8e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGHJCLEG_01721 0.0 asnB 6.3.5.4 E Asparagine synthase
HGHJCLEG_01722 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGHJCLEG_01723 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGHJCLEG_01724 6.3e-129 jag S R3H domain protein
HGHJCLEG_01725 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGHJCLEG_01726 6e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGHJCLEG_01727 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HGHJCLEG_01728 5.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGHJCLEG_01729 2e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGHJCLEG_01730 3.8e-34 yaaA S S4 domain protein YaaA
HGHJCLEG_01731 6.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGHJCLEG_01732 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGHJCLEG_01733 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGHJCLEG_01734 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HGHJCLEG_01735 2.8e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGHJCLEG_01736 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGHJCLEG_01737 2.4e-74 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGHJCLEG_01738 2.6e-100 deoR K sugar-binding domain protein
HGHJCLEG_01739 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HGHJCLEG_01740 2e-74 rplI J Binds to the 23S rRNA
HGHJCLEG_01741 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HGHJCLEG_01742 9e-207 yttB EGP Major facilitator Superfamily
HGHJCLEG_01743 9.1e-61
HGHJCLEG_01744 6.9e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HGHJCLEG_01746 7.5e-96 Z012_01130 S Fic/DOC family
HGHJCLEG_01748 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
HGHJCLEG_01749 7.6e-308 lmrA 3.6.3.44 V ABC transporter
HGHJCLEG_01751 3.1e-130 K response regulator
HGHJCLEG_01752 0.0 vicK 2.7.13.3 T Histidine kinase
HGHJCLEG_01753 2.4e-245 yycH S YycH protein
HGHJCLEG_01754 7.8e-149 yycI S YycH protein
HGHJCLEG_01755 2.3e-153 vicX 3.1.26.11 S domain protein
HGHJCLEG_01756 1.6e-214 htrA 3.4.21.107 O serine protease
HGHJCLEG_01757 4.3e-88
HGHJCLEG_01758 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGHJCLEG_01759 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HGHJCLEG_01760 5.5e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHJCLEG_01761 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGHJCLEG_01762 4.8e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGHJCLEG_01763 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGHJCLEG_01764 7.6e-09
HGHJCLEG_01765 6.3e-38 ykuJ S Protein of unknown function (DUF1797)
HGHJCLEG_01766 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGHJCLEG_01767 2.9e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
HGHJCLEG_01768 2.1e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HGHJCLEG_01769 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGHJCLEG_01770 2.7e-39 ptsH G phosphocarrier protein HPR
HGHJCLEG_01771 6.4e-27
HGHJCLEG_01772 0.0 clpE O Belongs to the ClpA ClpB family
HGHJCLEG_01773 7.5e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
HGHJCLEG_01774 8.4e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HGHJCLEG_01775 2.5e-13 M Lysin motif
HGHJCLEG_01776 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HGHJCLEG_01777 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HGHJCLEG_01778 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HGHJCLEG_01779 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGHJCLEG_01780 1.4e-234 S Tetratricopeptide repeat protein
HGHJCLEG_01781 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHJCLEG_01782 8.6e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHJCLEG_01783 5.1e-238 E amino acid
HGHJCLEG_01784 1.1e-130 npp S type I phosphodiesterase nucleotide pyrophosphatase
HGHJCLEG_01785 6.3e-52 npp S type I phosphodiesterase nucleotide pyrophosphatase
HGHJCLEG_01786 6e-214 yxiO S Vacuole effluxer Atg22 like
HGHJCLEG_01788 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGHJCLEG_01789 6.4e-32
HGHJCLEG_01790 1.4e-243 nhaC C Na H antiporter NhaC
HGHJCLEG_01791 1.6e-241 pbuX F xanthine permease
HGHJCLEG_01792 2.3e-278 pipD E Dipeptidase
HGHJCLEG_01793 2.8e-168 corA P CorA-like Mg2+ transporter protein
HGHJCLEG_01794 3.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGHJCLEG_01795 6.6e-131 terC P membrane
HGHJCLEG_01796 1.9e-55 trxA O Belongs to the thioredoxin family
HGHJCLEG_01797 1e-25
HGHJCLEG_01798 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
HGHJCLEG_01799 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
HGHJCLEG_01800 4.1e-153 glcU U sugar transport
HGHJCLEG_01801 7.6e-272 yclK 2.7.13.3 T Histidine kinase
HGHJCLEG_01802 1.2e-134 K response regulator
HGHJCLEG_01804 1.3e-76 lytE M Lysin motif
HGHJCLEG_01805 1.1e-147 XK27_02985 S Cof-like hydrolase
HGHJCLEG_01806 1.9e-138 L Transposase
HGHJCLEG_01807 4.1e-19
HGHJCLEG_01808 3.5e-183 ampC V Beta-lactamase
HGHJCLEG_01809 3.1e-218 arcA 3.5.3.6 E Arginine
HGHJCLEG_01810 2.7e-79 argR K Regulates arginine biosynthesis genes
HGHJCLEG_01811 3.2e-259 E Arginine ornithine antiporter
HGHJCLEG_01812 1.4e-222 arcD U Amino acid permease
HGHJCLEG_01813 8.3e-72
HGHJCLEG_01814 9.9e-267 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HGHJCLEG_01815 1.2e-269 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HGHJCLEG_01816 3.9e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HGHJCLEG_01817 1.3e-124 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HGHJCLEG_01818 2.9e-184 G Major Facilitator
HGHJCLEG_01819 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
HGHJCLEG_01820 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HGHJCLEG_01821 3.6e-236 yagE E amino acid
HGHJCLEG_01822 1.2e-137 aroD S Serine hydrolase (FSH1)
HGHJCLEG_01823 1e-202 brnQ U Component of the transport system for branched-chain amino acids
HGHJCLEG_01824 6.2e-99 S D5 N terminal like
HGHJCLEG_01825 3.1e-51 S Bifunctional DNA primase/polymerase, N-terminal
HGHJCLEG_01827 8.5e-08
HGHJCLEG_01830 4e-21 S Helix-turn-helix domain
HGHJCLEG_01831 1e-16 K Transcriptional regulator
HGHJCLEG_01832 1e-09 M LysM domain
HGHJCLEG_01833 1.9e-134 L Belongs to the 'phage' integrase family
HGHJCLEG_01834 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HGHJCLEG_01835 9e-53 ysxB J Cysteine protease Prp
HGHJCLEG_01836 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HGHJCLEG_01837 2.6e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGHJCLEG_01838 1.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HGHJCLEG_01839 6.6e-114 J 2'-5' RNA ligase superfamily
HGHJCLEG_01840 6.4e-70 yqhY S Asp23 family, cell envelope-related function
HGHJCLEG_01841 8e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGHJCLEG_01842 4e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGHJCLEG_01843 6.5e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGHJCLEG_01844 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGHJCLEG_01845 5.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGHJCLEG_01846 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HGHJCLEG_01847 1.6e-76 argR K Regulates arginine biosynthesis genes
HGHJCLEG_01848 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
HGHJCLEG_01849 2.1e-52
HGHJCLEG_01850 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HGHJCLEG_01851 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGHJCLEG_01852 7.4e-209 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGHJCLEG_01853 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGHJCLEG_01854 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGHJCLEG_01855 2.4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGHJCLEG_01856 6.1e-129 stp 3.1.3.16 T phosphatase
HGHJCLEG_01857 0.0 KLT serine threonine protein kinase
HGHJCLEG_01858 1.2e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGHJCLEG_01859 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HGHJCLEG_01860 3.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
HGHJCLEG_01861 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HGHJCLEG_01862 4.7e-58 asp S Asp23 family, cell envelope-related function
HGHJCLEG_01863 0.0 yloV S DAK2 domain fusion protein YloV
HGHJCLEG_01864 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGHJCLEG_01865 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGHJCLEG_01866 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGHJCLEG_01867 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGHJCLEG_01868 0.0 smc D Required for chromosome condensation and partitioning
HGHJCLEG_01869 1.9e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGHJCLEG_01870 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGHJCLEG_01871 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGHJCLEG_01872 6.5e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HGHJCLEG_01873 7e-40 ylqC S Belongs to the UPF0109 family
HGHJCLEG_01874 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGHJCLEG_01875 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HGHJCLEG_01876 2.5e-161 yfnA E amino acid
HGHJCLEG_01877 2e-80 yfnA E amino acid
HGHJCLEG_01878 3.9e-12
HGHJCLEG_01879 2.2e-154 P Belongs to the nlpA lipoprotein family
HGHJCLEG_01880 1.4e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGHJCLEG_01881 4.8e-51 S Iron-sulfur cluster assembly protein
HGHJCLEG_01882 2.6e-150
HGHJCLEG_01883 3.3e-181
HGHJCLEG_01884 2.8e-85 dut S Protein conserved in bacteria
HGHJCLEG_01888 8e-103 K Transcriptional regulator
HGHJCLEG_01889 1.2e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HGHJCLEG_01890 4.6e-16 K Cro/C1-type HTH DNA-binding domain
HGHJCLEG_01891 1.6e-109 dedA S SNARE-like domain protein
HGHJCLEG_01892 2.8e-101 S Protein of unknown function (DUF1461)
HGHJCLEG_01893 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGHJCLEG_01894 6.6e-93 yutD S Protein of unknown function (DUF1027)
HGHJCLEG_01895 4.7e-111 S Calcineurin-like phosphoesterase
HGHJCLEG_01896 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGHJCLEG_01897 2.1e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
HGHJCLEG_01898 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HGHJCLEG_01899 1.3e-216 uhpT EGP Major facilitator Superfamily
HGHJCLEG_01900 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
HGHJCLEG_01901 1.1e-124 arcD S C4-dicarboxylate anaerobic carrier
HGHJCLEG_01902 2.4e-16 arcD S C4-dicarboxylate anaerobic carrier
HGHJCLEG_01903 2.6e-109 L Transposase
HGHJCLEG_01904 5.1e-133 K Transcriptional regulatory protein, C-terminal domain protein
HGHJCLEG_01905 4.6e-160 pstS P Phosphate
HGHJCLEG_01906 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
HGHJCLEG_01907 2.6e-155 pstA P Phosphate transport system permease protein PstA
HGHJCLEG_01908 4e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGHJCLEG_01909 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
HGHJCLEG_01911 4.6e-36 K Bacterial transcriptional regulator
HGHJCLEG_01912 4e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
HGHJCLEG_01913 1.3e-38
HGHJCLEG_01914 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGHJCLEG_01915 8.4e-207 gldA 1.1.1.6 C dehydrogenase
HGHJCLEG_01916 4.7e-63 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHJCLEG_01917 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HGHJCLEG_01918 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
HGHJCLEG_01919 1.2e-97 2.3.1.128 K acetyltransferase
HGHJCLEG_01920 3.9e-187
HGHJCLEG_01921 1.4e-12 K Transcriptional regulator, HxlR family
HGHJCLEG_01922 3.7e-40 L Transposase
HGHJCLEG_01923 2.4e-36 L Transposase
HGHJCLEG_01924 9.5e-80 L Transposase
HGHJCLEG_01925 2.3e-84 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HGHJCLEG_01926 6.5e-179 ABC-SBP S ABC transporter
HGHJCLEG_01927 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGHJCLEG_01929 2.9e-96 S reductase
HGHJCLEG_01930 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HGHJCLEG_01931 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HGHJCLEG_01932 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGHJCLEG_01933 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HGHJCLEG_01934 1.8e-195 coiA 3.6.4.12 S Competence protein
HGHJCLEG_01935 6.8e-267 pipD E Dipeptidase
HGHJCLEG_01936 3.1e-113 yjbH Q Thioredoxin
HGHJCLEG_01937 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HGHJCLEG_01938 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGHJCLEG_01939 1e-159 sufD O Uncharacterized protein family (UPF0051)
HGHJCLEG_01940 2e-42 lytE M LysM domain protein
HGHJCLEG_01941 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HGHJCLEG_01942 6.6e-174 K AI-2E family transporter
HGHJCLEG_01943 1.2e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HGHJCLEG_01944 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGHJCLEG_01945 1.4e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HGHJCLEG_01946 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGHJCLEG_01947 5.1e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGHJCLEG_01948 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGHJCLEG_01949 7.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGHJCLEG_01950 1.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HGHJCLEG_01951 5.3e-132 K LysR substrate binding domain
HGHJCLEG_01952 1.6e-52 azlD S branched-chain amino acid
HGHJCLEG_01953 2.7e-139 azlC E AzlC protein
HGHJCLEG_01954 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
HGHJCLEG_01955 3.8e-125 K response regulator
HGHJCLEG_01956 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGHJCLEG_01957 4e-170 deoR K sugar-binding domain protein
HGHJCLEG_01958 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HGHJCLEG_01959 3.2e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HGHJCLEG_01960 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGHJCLEG_01961 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGHJCLEG_01962 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
HGHJCLEG_01963 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGHJCLEG_01964 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
HGHJCLEG_01965 5e-154 spo0J K Belongs to the ParB family
HGHJCLEG_01966 3.6e-140 soj D Sporulation initiation inhibitor
HGHJCLEG_01967 1.5e-143 noc K Belongs to the ParB family
HGHJCLEG_01968 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HGHJCLEG_01969 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HGHJCLEG_01970 6.6e-170 rihC 3.2.2.1 F Nucleoside
HGHJCLEG_01971 1.3e-218 nupG F Nucleoside transporter
HGHJCLEG_01972 1.6e-220 cycA E Amino acid permease
HGHJCLEG_01973 1.9e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHJCLEG_01974 2.2e-263 glnP P ABC transporter
HGHJCLEG_01975 4.5e-74 L transposase and inactivated derivatives, IS30 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)