ORF_ID e_value Gene_name EC_number CAZy COGs Description
IAFDNKHD_00001 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00002 3.2e-47 rpsJ J Involved in the binding of tRNA to the ribosomes
IAFDNKHD_00003 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAFDNKHD_00004 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IAFDNKHD_00005 4.9e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IAFDNKHD_00006 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IAFDNKHD_00007 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IAFDNKHD_00008 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IAFDNKHD_00009 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IAFDNKHD_00010 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IAFDNKHD_00011 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
IAFDNKHD_00012 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IAFDNKHD_00013 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IAFDNKHD_00014 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IAFDNKHD_00015 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IAFDNKHD_00016 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAFDNKHD_00017 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAFDNKHD_00018 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAFDNKHD_00019 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IAFDNKHD_00020 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAFDNKHD_00021 2.9e-24 rpmD J Ribosomal protein L30
IAFDNKHD_00022 1.3e-62 rplO J Binds to the 23S rRNA
IAFDNKHD_00023 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IAFDNKHD_00024 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IAFDNKHD_00025 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAFDNKHD_00026 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IAFDNKHD_00027 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAFDNKHD_00028 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IAFDNKHD_00029 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAFDNKHD_00030 1.1e-62 rplQ J Ribosomal protein L17
IAFDNKHD_00031 3.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAFDNKHD_00032 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAFDNKHD_00033 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAFDNKHD_00034 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IAFDNKHD_00035 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAFDNKHD_00036 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IAFDNKHD_00037 8e-140 IQ reductase
IAFDNKHD_00038 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
IAFDNKHD_00039 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IAFDNKHD_00040 1.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IAFDNKHD_00041 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IAFDNKHD_00042 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAFDNKHD_00043 1.8e-201 camS S sex pheromone
IAFDNKHD_00044 5.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAFDNKHD_00045 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IAFDNKHD_00046 9.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAFDNKHD_00047 8.7e-187 yegS 2.7.1.107 G Lipid kinase
IAFDNKHD_00048 4.5e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAFDNKHD_00050 3.8e-197 L Recombinase
IAFDNKHD_00051 1.2e-14 S Recombinase
IAFDNKHD_00052 7.7e-118 L Recombinase zinc beta ribbon domain
IAFDNKHD_00054 4.5e-52 S Bacteriophage holin family
IAFDNKHD_00055 1.9e-46 S Phage head-tail joining protein
IAFDNKHD_00056 2.2e-31 S Phage gp6-like head-tail connector protein
IAFDNKHD_00057 7.1e-172 S Phage capsid family
IAFDNKHD_00058 1e-71 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IAFDNKHD_00059 1.3e-216 S Phage portal protein
IAFDNKHD_00060 2.8e-11 K Antidote-toxin recognition MazE, bacterial antitoxin
IAFDNKHD_00063 1.5e-289 S overlaps another CDS with the same product name
IAFDNKHD_00064 1.1e-24 S Domain of unknown function (DUF5049)
IAFDNKHD_00065 6e-53 S Psort location Cytoplasmic, score
IAFDNKHD_00066 4.4e-201 2.1.1.72 KL DNA methylase
IAFDNKHD_00067 5.7e-92
IAFDNKHD_00068 2.7e-72 V HNH nucleases
IAFDNKHD_00069 1.6e-82
IAFDNKHD_00070 1.1e-253 L SNF2 family N-terminal domain
IAFDNKHD_00071 2.1e-45 S VRR_NUC
IAFDNKHD_00072 0.0 S Phage plasmid primase, P4
IAFDNKHD_00073 2.5e-70 S Psort location Cytoplasmic, score
IAFDNKHD_00074 0.0 polA_2 2.7.7.7 L DNA polymerase
IAFDNKHD_00075 9.5e-95 S Protein of unknown function (DUF2815)
IAFDNKHD_00076 9.1e-201 L Protein of unknown function (DUF2800)
IAFDNKHD_00077 1.6e-28
IAFDNKHD_00078 1.1e-22
IAFDNKHD_00080 7.2e-16 S Domain of unknown function (DUF1837)
IAFDNKHD_00081 6.7e-122 F helicase superfamily c-terminal domain
IAFDNKHD_00082 3.9e-23 K Cro/C1-type HTH DNA-binding domain
IAFDNKHD_00083 2.2e-290 2.1.1.72 V type I restriction-modification system
IAFDNKHD_00084 6.4e-32 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
IAFDNKHD_00085 5.2e-39 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IAFDNKHD_00086 1.9e-175 xerC L Belongs to the 'phage' integrase family
IAFDNKHD_00087 4.2e-52 3.1.21.3 V Type I restriction
IAFDNKHD_00088 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IAFDNKHD_00090 1.7e-37 S Protein of unknown function (DUF3021)
IAFDNKHD_00091 2.2e-65 K LytTr DNA-binding domain
IAFDNKHD_00092 3e-124 cylB V ABC-2 type transporter
IAFDNKHD_00093 1.7e-127 cylA V ABC transporter
IAFDNKHD_00094 9.1e-284 L Recombinase
IAFDNKHD_00095 2.1e-283 L Recombinase zinc beta ribbon domain
IAFDNKHD_00096 4.7e-27
IAFDNKHD_00097 3.8e-69 M Glycosyl hydrolases family 25
IAFDNKHD_00098 1.2e-20 M Glycosyl hydrolases family 25
IAFDNKHD_00099 3.6e-70 S Bacteriophage holin family
IAFDNKHD_00100 6.9e-68 S Phage head-tail joining protein
IAFDNKHD_00101 4.3e-43 S Phage gp6-like head-tail connector protein
IAFDNKHD_00102 2.8e-221 S Phage capsid family
IAFDNKHD_00103 1.4e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IAFDNKHD_00104 6.3e-243 S Phage portal protein
IAFDNKHD_00105 3e-306 S overlaps another CDS with the same product name
IAFDNKHD_00106 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00107 1.8e-30 S Domain of unknown function (DUF5049)
IAFDNKHD_00108 3.3e-112 S Psort location Cytoplasmic, score
IAFDNKHD_00109 2.9e-229 2.1.1.72 KL DNA methylase
IAFDNKHD_00110 3.1e-98
IAFDNKHD_00111 8.9e-86
IAFDNKHD_00112 3.8e-254 L SNF2 family N-terminal domain
IAFDNKHD_00113 7.1e-46 S VRR_NUC
IAFDNKHD_00114 0.0 S Phage plasmid primase, P4
IAFDNKHD_00115 2.8e-69 S Psort location Cytoplasmic, score
IAFDNKHD_00116 0.0 polA_2 2.7.7.7 L DNA polymerase
IAFDNKHD_00117 1.4e-98 S Protein of unknown function (DUF2815)
IAFDNKHD_00118 4e-212 L Protein of unknown function (DUF2800)
IAFDNKHD_00119 2e-41
IAFDNKHD_00120 8.5e-25
IAFDNKHD_00121 6.5e-73 K DNA-templated transcription, initiation
IAFDNKHD_00122 1.5e-18 S Domain of unknown function (DUF1837)
IAFDNKHD_00123 8.9e-135 F helicase superfamily c-terminal domain
IAFDNKHD_00124 4.9e-23 K Cro/C1-type HTH DNA-binding domain
IAFDNKHD_00125 2.3e-72 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IAFDNKHD_00126 1.1e-12 KL Eco57I restriction-modification methylase
IAFDNKHD_00127 5.1e-139 L Bacterial dnaA protein
IAFDNKHD_00128 5.8e-230 L Integrase core domain
IAFDNKHD_00129 1.9e-86 2.1.1.72, 3.1.21.4 L site-specific DNA-methyltransferase (adenine-specific) activity
IAFDNKHD_00130 0.0 L Type III restriction enzyme, res subunit
IAFDNKHD_00131 5.8e-288 S Protein of unknown function DUF262
IAFDNKHD_00132 8.1e-07
IAFDNKHD_00133 5.3e-54 U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IAFDNKHD_00134 3.5e-174 S Domain of unknown function (DUF389)
IAFDNKHD_00135 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00136 1e-88 L Recombinase
IAFDNKHD_00137 3.3e-71 K DNA binding
IAFDNKHD_00138 1e-120 L helicase activity
IAFDNKHD_00139 4.9e-207 L helicase activity
IAFDNKHD_00141 1.8e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAFDNKHD_00142 2e-163 L PFAM Integrase catalytic region
IAFDNKHD_00143 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
IAFDNKHD_00144 7.9e-35 copZ C Heavy-metal-associated domain
IAFDNKHD_00145 1.2e-94 dps P Belongs to the Dps family
IAFDNKHD_00146 5.2e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IAFDNKHD_00147 6.3e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
IAFDNKHD_00148 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
IAFDNKHD_00149 2e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
IAFDNKHD_00150 1.5e-69 L Recombinase
IAFDNKHD_00151 7.6e-67 L Recombinase
IAFDNKHD_00152 1.7e-21 L recombinase activity
IAFDNKHD_00153 4.7e-19 L Recombinase zinc beta ribbon domain
IAFDNKHD_00154 1.3e-68 L Recombinase zinc beta ribbon domain
IAFDNKHD_00155 8.2e-19
IAFDNKHD_00156 2.4e-29 S Bacteriophage holin family
IAFDNKHD_00157 7.2e-54 S Phage head-tail joining protein
IAFDNKHD_00158 1.3e-39 S Phage gp6-like head-tail connector protein
IAFDNKHD_00159 8.8e-172 S Phage capsid family
IAFDNKHD_00160 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IAFDNKHD_00161 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
IAFDNKHD_00162 6.6e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAFDNKHD_00163 1.2e-102 pncA Q Isochorismatase family
IAFDNKHD_00164 6.8e-259 S Uncharacterised protein family (UPF0236)
IAFDNKHD_00165 1.1e-91 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00166 3.7e-205 amtB P ammonium transporter
IAFDNKHD_00167 6.8e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
IAFDNKHD_00168 1.9e-83 yvbK 3.1.3.25 K GNAT family
IAFDNKHD_00169 1.7e-91
IAFDNKHD_00170 1.4e-65 pnb C nitroreductase
IAFDNKHD_00171 2.4e-75 ogt 2.1.1.63 L Methyltransferase
IAFDNKHD_00172 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
IAFDNKHD_00173 6.8e-67 S Protein of unknown function (DUF3021)
IAFDNKHD_00174 6e-76 K LytTr DNA-binding domain
IAFDNKHD_00175 1.1e-92 K Acetyltransferase (GNAT) family
IAFDNKHD_00176 1.1e-116 ybhL S Belongs to the BI1 family
IAFDNKHD_00177 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IAFDNKHD_00178 3e-195 S Protein of unknown function (DUF3114)
IAFDNKHD_00179 2.2e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IAFDNKHD_00180 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IAFDNKHD_00181 1.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
IAFDNKHD_00182 9.1e-62 S Domain of unknown function (DUF4828)
IAFDNKHD_00183 5.9e-191 mocA S Oxidoreductase
IAFDNKHD_00184 1.9e-231 yfmL L DEAD DEAH box helicase
IAFDNKHD_00186 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IAFDNKHD_00187 6.1e-55
IAFDNKHD_00188 8.6e-50 L Transposase IS200 like
IAFDNKHD_00189 5.5e-185 L transposase, IS605 OrfB family
IAFDNKHD_00190 1.3e-67 gtcA S Teichoic acid glycosylation protein
IAFDNKHD_00191 1.4e-78 fld C Flavodoxin
IAFDNKHD_00192 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
IAFDNKHD_00193 1.6e-221 arcT 2.6.1.1 E Aminotransferase
IAFDNKHD_00194 9.5e-256 E Arginine ornithine antiporter
IAFDNKHD_00195 3.4e-280 yjeM E Amino Acid
IAFDNKHD_00196 1.8e-143 yihY S Belongs to the UPF0761 family
IAFDNKHD_00197 6.6e-34 S Protein of unknown function (DUF2922)
IAFDNKHD_00198 4.9e-31
IAFDNKHD_00199 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
IAFDNKHD_00200 1.9e-146 cps1D M Domain of unknown function (DUF4422)
IAFDNKHD_00201 2.3e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IAFDNKHD_00202 2.1e-117 rfbP 2.7.8.6 M Bacterial sugar transferase
IAFDNKHD_00203 0.0 2.7.7.6 M Peptidase family M23
IAFDNKHD_00204 0.0 G Peptidase_C39 like family
IAFDNKHD_00205 6.1e-25
IAFDNKHD_00206 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
IAFDNKHD_00207 3.2e-211 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
IAFDNKHD_00208 4.7e-76 M transferase activity, transferring glycosyl groups
IAFDNKHD_00209 3.1e-90 cps3F
IAFDNKHD_00210 3.9e-28 M biosynthesis protein
IAFDNKHD_00211 3.4e-76 rgpB GT2 M Glycosyl transferase family 2
IAFDNKHD_00212 1.8e-67 S Glycosyltransferase like family
IAFDNKHD_00213 1.3e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
IAFDNKHD_00214 2.6e-72 S Acyltransferase family
IAFDNKHD_00215 5.8e-83
IAFDNKHD_00216 1.2e-145 rfbJ M Glycosyl transferase family 2
IAFDNKHD_00217 1.8e-134
IAFDNKHD_00218 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IAFDNKHD_00219 9.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IAFDNKHD_00220 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IAFDNKHD_00221 2.7e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IAFDNKHD_00222 1.9e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IAFDNKHD_00223 0.0 csd1 3.5.1.28 G domain, Protein
IAFDNKHD_00224 7.4e-163 yueF S AI-2E family transporter
IAFDNKHD_00225 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IAFDNKHD_00226 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00227 3.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAFDNKHD_00228 0.0 M NlpC/P60 family
IAFDNKHD_00229 0.0 S Peptidase, M23
IAFDNKHD_00230 0.0 bamA GM domain, Protein
IAFDNKHD_00231 1.1e-200 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_00232 1.5e-08 gntR1 K Transcriptional regulator, GntR family
IAFDNKHD_00233 2.1e-32 gntR1 K Transcriptional regulator, GntR family
IAFDNKHD_00234 4.4e-155 V ABC transporter, ATP-binding protein
IAFDNKHD_00235 5.5e-116
IAFDNKHD_00236 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
IAFDNKHD_00237 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00238 1.7e-100 S Pfam:DUF3816
IAFDNKHD_00239 5.2e-167 S Uncharacterised protein family (UPF0236)
IAFDNKHD_00240 2.7e-70 S Uncharacterised protein family (UPF0236)
IAFDNKHD_00241 0.0 clpE O Belongs to the ClpA ClpB family
IAFDNKHD_00242 6.4e-27
IAFDNKHD_00243 2.7e-39 ptsH G phosphocarrier protein HPR
IAFDNKHD_00244 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAFDNKHD_00245 2.1e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IAFDNKHD_00246 2.9e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
IAFDNKHD_00247 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAFDNKHD_00248 6.3e-38 ykuJ S Protein of unknown function (DUF1797)
IAFDNKHD_00260 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
IAFDNKHD_00261 2.2e-152 lmrB EGP Major facilitator Superfamily
IAFDNKHD_00262 2.5e-57 lmrB EGP Major facilitator Superfamily
IAFDNKHD_00263 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00264 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IAFDNKHD_00265 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAFDNKHD_00266 1e-159 sufD O Uncharacterized protein family (UPF0051)
IAFDNKHD_00267 2e-42 lytE M LysM domain protein
IAFDNKHD_00268 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00269 0.0 oppD EP Psort location Cytoplasmic, score
IAFDNKHD_00270 1.2e-86 lytE M LysM domain protein
IAFDNKHD_00271 5.3e-231 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00272 3e-98 xth 3.1.11.2 L exodeoxyribonuclease III
IAFDNKHD_00273 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00274 2.7e-21 xth 3.1.11.2 L exodeoxyribonuclease III
IAFDNKHD_00275 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IAFDNKHD_00276 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
IAFDNKHD_00277 5.3e-153 yeaE S Aldo keto
IAFDNKHD_00278 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
IAFDNKHD_00279 1.2e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IAFDNKHD_00280 2.5e-77 S Psort location Cytoplasmic, score
IAFDNKHD_00281 1.6e-54 S Short repeat of unknown function (DUF308)
IAFDNKHD_00282 1e-23
IAFDNKHD_00283 1.7e-102 V VanZ like family
IAFDNKHD_00284 7.7e-231 cycA E Amino acid permease
IAFDNKHD_00285 2.8e-84 perR P Belongs to the Fur family
IAFDNKHD_00286 1e-257 EGP Major facilitator Superfamily
IAFDNKHD_00287 7.9e-94 tag 3.2.2.20 L glycosylase
IAFDNKHD_00288 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAFDNKHD_00289 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAFDNKHD_00290 7.6e-42
IAFDNKHD_00291 1.1e-300 ytgP S Polysaccharide biosynthesis protein
IAFDNKHD_00292 5.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAFDNKHD_00293 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
IAFDNKHD_00294 7.3e-86 uspA T Belongs to the universal stress protein A family
IAFDNKHD_00295 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IAFDNKHD_00296 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
IAFDNKHD_00297 1.5e-112
IAFDNKHD_00298 1.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
IAFDNKHD_00299 1.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAFDNKHD_00300 2.4e-234 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00301 1.8e-31
IAFDNKHD_00302 3.6e-109 S CAAX protease self-immunity
IAFDNKHD_00303 1.9e-43
IAFDNKHD_00305 6.4e-69
IAFDNKHD_00306 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAFDNKHD_00307 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IAFDNKHD_00308 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IAFDNKHD_00309 1e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IAFDNKHD_00310 1.6e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IAFDNKHD_00311 3.4e-211 folP 2.5.1.15 H dihydropteroate synthase
IAFDNKHD_00312 5.1e-43
IAFDNKHD_00313 1.6e-39
IAFDNKHD_00315 1.9e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IAFDNKHD_00316 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IAFDNKHD_00317 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00318 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_00319 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IAFDNKHD_00320 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IAFDNKHD_00321 9.4e-38 yheA S Belongs to the UPF0342 family
IAFDNKHD_00322 1.3e-218 yhaO L Ser Thr phosphatase family protein
IAFDNKHD_00323 0.0 L AAA domain
IAFDNKHD_00324 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IAFDNKHD_00325 9.4e-12 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00326 2.4e-220 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00328 3.2e-77 hit FG histidine triad
IAFDNKHD_00329 3.9e-136 ecsA V ABC transporter, ATP-binding protein
IAFDNKHD_00330 1.3e-218 ecsB U ABC transporter
IAFDNKHD_00331 1.2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IAFDNKHD_00332 3.1e-22 S YSIRK type signal peptide
IAFDNKHD_00333 3.2e-264 L PFAM Integrase catalytic region
IAFDNKHD_00334 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
IAFDNKHD_00335 1.8e-56 ytzB S Small secreted protein
IAFDNKHD_00336 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IAFDNKHD_00337 5e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IAFDNKHD_00338 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IAFDNKHD_00339 1.9e-119 ybhL S Belongs to the BI1 family
IAFDNKHD_00340 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00341 2e-115 yoaK S Protein of unknown function (DUF1275)
IAFDNKHD_00342 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAFDNKHD_00343 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IAFDNKHD_00344 1.7e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAFDNKHD_00345 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAFDNKHD_00346 5.9e-223 dnaB L replication initiation and membrane attachment
IAFDNKHD_00347 6.8e-157 dnaI L Primosomal protein DnaI
IAFDNKHD_00348 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAFDNKHD_00349 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IAFDNKHD_00350 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAFDNKHD_00351 2.4e-95 yqeG S HAD phosphatase, family IIIA
IAFDNKHD_00352 4.8e-218 yqeH S Ribosome biogenesis GTPase YqeH
IAFDNKHD_00353 1.9e-47 yhbY J RNA-binding protein
IAFDNKHD_00354 4.5e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IAFDNKHD_00355 6.2e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IAFDNKHD_00356 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IAFDNKHD_00357 9.7e-135 yqeM Q Methyltransferase
IAFDNKHD_00358 5.3e-209 ylbM S Belongs to the UPF0348 family
IAFDNKHD_00359 4.9e-99 yceD S Uncharacterized ACR, COG1399
IAFDNKHD_00360 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IAFDNKHD_00361 5.8e-140 L PFAM Integrase catalytic region
IAFDNKHD_00362 1.5e-121 K response regulator
IAFDNKHD_00363 4.1e-278 arlS 2.7.13.3 T Histidine kinase
IAFDNKHD_00364 7.4e-267 yjeM E Amino Acid
IAFDNKHD_00365 2.9e-235 V MatE
IAFDNKHD_00366 1.3e-67 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IAFDNKHD_00367 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IAFDNKHD_00368 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IAFDNKHD_00369 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAFDNKHD_00370 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IAFDNKHD_00371 6.7e-59 yodB K Transcriptional regulator, HxlR family
IAFDNKHD_00372 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAFDNKHD_00373 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IAFDNKHD_00374 5.6e-115 rlpA M PFAM NLP P60 protein
IAFDNKHD_00375 2.3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
IAFDNKHD_00376 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IAFDNKHD_00377 7.3e-120 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_00378 2.2e-96 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_00379 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_00380 1.6e-67 yneR S Belongs to the HesB IscA family
IAFDNKHD_00381 0.0 S membrane
IAFDNKHD_00382 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IAFDNKHD_00383 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IAFDNKHD_00384 6.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAFDNKHD_00385 6.2e-109 gluP 3.4.21.105 S Peptidase, S54 family
IAFDNKHD_00386 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
IAFDNKHD_00387 2.1e-182 glk 2.7.1.2 G Glucokinase
IAFDNKHD_00388 3.4e-67 yqhL P Rhodanese-like protein
IAFDNKHD_00389 5.9e-22 S Protein of unknown function (DUF3042)
IAFDNKHD_00390 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IAFDNKHD_00391 4e-264 glnA 6.3.1.2 E glutamine synthetase
IAFDNKHD_00392 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAFDNKHD_00393 7e-22 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IAFDNKHD_00394 1.2e-138 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IAFDNKHD_00395 1.5e-140 L PFAM Integrase catalytic region
IAFDNKHD_00396 3.9e-12
IAFDNKHD_00397 2.2e-154 P Belongs to the nlpA lipoprotein family
IAFDNKHD_00398 1.4e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAFDNKHD_00399 4.8e-51 S Iron-sulfur cluster assembly protein
IAFDNKHD_00400 2.6e-150
IAFDNKHD_00401 3.3e-181
IAFDNKHD_00402 2.8e-85 dut S Protein conserved in bacteria
IAFDNKHD_00406 8e-103 K Transcriptional regulator
IAFDNKHD_00407 6.1e-235 L transposase IS116 IS110 IS902 family protein
IAFDNKHD_00408 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
IAFDNKHD_00409 9e-53 ysxB J Cysteine protease Prp
IAFDNKHD_00410 9.6e-38 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IAFDNKHD_00411 2.6e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IAFDNKHD_00412 1.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IAFDNKHD_00413 6.6e-114 J 2'-5' RNA ligase superfamily
IAFDNKHD_00414 6.4e-70 yqhY S Asp23 family, cell envelope-related function
IAFDNKHD_00415 8e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAFDNKHD_00416 4e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAFDNKHD_00417 6.5e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IAFDNKHD_00418 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IAFDNKHD_00419 5.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IAFDNKHD_00420 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IAFDNKHD_00421 1.6e-76 argR K Regulates arginine biosynthesis genes
IAFDNKHD_00422 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
IAFDNKHD_00423 2.1e-52
IAFDNKHD_00424 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IAFDNKHD_00425 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IAFDNKHD_00426 7.4e-209 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAFDNKHD_00427 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAFDNKHD_00428 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IAFDNKHD_00429 2.4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAFDNKHD_00430 6.1e-129 stp 3.1.3.16 T phosphatase
IAFDNKHD_00431 0.0 KLT serine threonine protein kinase
IAFDNKHD_00432 1.2e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IAFDNKHD_00433 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IAFDNKHD_00434 6.2e-11 thiN 2.7.6.2 H thiamine pyrophosphokinase
IAFDNKHD_00435 1.6e-85 thiN 2.7.6.2 H thiamine pyrophosphokinase
IAFDNKHD_00436 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IAFDNKHD_00437 4.7e-58 asp S Asp23 family, cell envelope-related function
IAFDNKHD_00438 0.0 yloV S DAK2 domain fusion protein YloV
IAFDNKHD_00439 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAFDNKHD_00440 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IAFDNKHD_00441 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAFDNKHD_00442 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IAFDNKHD_00443 0.0 smc D Required for chromosome condensation and partitioning
IAFDNKHD_00444 1.9e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IAFDNKHD_00445 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IAFDNKHD_00446 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAFDNKHD_00447 6.5e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IAFDNKHD_00448 7e-40 ylqC S Belongs to the UPF0109 family
IAFDNKHD_00449 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAFDNKHD_00450 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IAFDNKHD_00451 2.5e-161 yfnA E amino acid
IAFDNKHD_00452 2e-80 yfnA E amino acid
IAFDNKHD_00453 6.2e-260 S Uncharacterised protein family (UPF0236)
IAFDNKHD_00454 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IAFDNKHD_00455 3.4e-124 L transposase IS116 IS110 IS902 family protein
IAFDNKHD_00456 3.1e-83 L transposase IS116 IS110 IS902 family protein
IAFDNKHD_00457 6.2e-260 S Uncharacterised protein family (UPF0236)
IAFDNKHD_00458 8.5e-34
IAFDNKHD_00459 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
IAFDNKHD_00460 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
IAFDNKHD_00461 3.8e-10
IAFDNKHD_00462 5.7e-186 lacR K Transcriptional regulator
IAFDNKHD_00463 0.0 lacS G Transporter
IAFDNKHD_00464 0.0 lacZ 3.2.1.23 G -beta-galactosidase
IAFDNKHD_00465 9.3e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IAFDNKHD_00466 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IAFDNKHD_00467 9.6e-61 L PFAM transposase IS200-family protein
IAFDNKHD_00468 9.7e-230 L transposase, IS605 OrfB family
IAFDNKHD_00469 3.7e-85 yxjG_1 E methionine synthase, vitamin-B12 independent
IAFDNKHD_00470 8.9e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IAFDNKHD_00471 2.7e-222 mdtG EGP Major facilitator Superfamily
IAFDNKHD_00472 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
IAFDNKHD_00473 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAFDNKHD_00474 4.2e-51 L Transposase IS200 like
IAFDNKHD_00475 2.5e-185 L transposase, IS605 OrfB family
IAFDNKHD_00477 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00478 2.7e-120 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IAFDNKHD_00479 6.3e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IAFDNKHD_00480 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
IAFDNKHD_00481 0.0 trxB2 1.8.1.9 C Thioredoxin domain
IAFDNKHD_00482 4.2e-272 pipD E Dipeptidase
IAFDNKHD_00483 7.3e-293 yjbQ P TrkA C-terminal domain protein
IAFDNKHD_00484 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IAFDNKHD_00485 3.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAFDNKHD_00486 3.2e-89
IAFDNKHD_00487 8.1e-35
IAFDNKHD_00488 2.3e-08 K Transcriptional regulator, HxlR family
IAFDNKHD_00489 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00490 2.9e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IAFDNKHD_00491 7.4e-142 epsB M biosynthesis protein
IAFDNKHD_00492 4.1e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IAFDNKHD_00493 4e-138 cps2D 5.1.3.2 M RmlD substrate binding domain
IAFDNKHD_00494 3.8e-90 tuaA M Bacterial sugar transferase
IAFDNKHD_00495 3.5e-42 tuaG GT2 M Glycosyltransferase like family 2
IAFDNKHD_00496 3.2e-44 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
IAFDNKHD_00497 5.5e-51 waaB GT4 M Glycosyl transferases group 1
IAFDNKHD_00498 1.3e-35 M Glycosyltransferase, group 2 family protein
IAFDNKHD_00499 9.7e-58 M Glycosyltransferase like family 2
IAFDNKHD_00501 6.8e-108 S Polysaccharide biosynthesis protein
IAFDNKHD_00502 4e-45 MA20_17390 GT4 M Glycosyl transferases group 1
IAFDNKHD_00503 5.7e-81 tagB 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IAFDNKHD_00504 2e-89 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 H 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
IAFDNKHD_00505 3e-97 4.1.1.35 M Male sterility protein
IAFDNKHD_00506 7.8e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IAFDNKHD_00507 2.7e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IAFDNKHD_00509 5.1e-165 L Integrase core domain
IAFDNKHD_00510 1.4e-57 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IAFDNKHD_00513 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00514 3.4e-76 S SIR2-like domain
IAFDNKHD_00515 7.4e-103 S Domain of unknown function DUF87
IAFDNKHD_00516 6.9e-104 L PFAM Integrase catalytic region
IAFDNKHD_00517 4.4e-11 L PFAM Integrase catalytic region
IAFDNKHD_00518 3.7e-40 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00519 1.1e-69 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
IAFDNKHD_00520 1.8e-78 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00521 2.6e-61 XK27_01125 L PFAM IS66 Orf2 family protein
IAFDNKHD_00522 6.7e-80 L Transposase IS66 family
IAFDNKHD_00523 6.1e-188 L Transposase IS66 family
IAFDNKHD_00524 4e-21
IAFDNKHD_00525 1.2e-100
IAFDNKHD_00527 3.2e-53 YPO0284 GM NAD(P)H-binding
IAFDNKHD_00529 5.5e-29 S Protein of unknown function (DUF4065)
IAFDNKHD_00530 4.8e-50 doc S Fic/DOC family
IAFDNKHD_00531 1.8e-09
IAFDNKHD_00533 1.1e-43
IAFDNKHD_00534 1.4e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IAFDNKHD_00535 5.5e-248 mmuP E amino acid
IAFDNKHD_00537 4.7e-67 L PFAM transposase IS200-family protein
IAFDNKHD_00538 1.2e-227 L transposase, IS605 OrfB family
IAFDNKHD_00539 1.2e-22 T Toxin-antitoxin system, toxin component, MazF family
IAFDNKHD_00540 2e-36
IAFDNKHD_00541 1.5e-06 D nuclear chromosome segregation
IAFDNKHD_00542 0.0 snf 2.7.11.1 KL domain protein
IAFDNKHD_00543 5.9e-143 ywqE 3.1.3.48 GM PHP domain protein
IAFDNKHD_00544 4.9e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IAFDNKHD_00545 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IAFDNKHD_00546 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
IAFDNKHD_00547 7.3e-71
IAFDNKHD_00548 3.1e-101 fic D Fic/DOC family
IAFDNKHD_00549 3.1e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IAFDNKHD_00550 1.7e-151 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IAFDNKHD_00551 1.3e-28
IAFDNKHD_00552 1.3e-146
IAFDNKHD_00553 1.2e-24
IAFDNKHD_00554 4.9e-111 lssY 3.6.1.27 I Acid phosphatase homologues
IAFDNKHD_00555 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IAFDNKHD_00556 1.5e-140 L PFAM Integrase catalytic region
IAFDNKHD_00557 3.2e-107 L Transposase
IAFDNKHD_00558 8.2e-66 L Integrase core domain
IAFDNKHD_00559 2.1e-123 L Integrase core domain
IAFDNKHD_00560 5.1e-139 L Bacterial dnaA protein
IAFDNKHD_00561 1.6e-116 L Transposase
IAFDNKHD_00562 4.8e-139 L PFAM transposase IS116 IS110 IS902
IAFDNKHD_00563 5.7e-228 clcA_2 P Chloride transporter, ClC family
IAFDNKHD_00564 1.5e-236 L Transposase
IAFDNKHD_00565 3.6e-11
IAFDNKHD_00566 1.2e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IAFDNKHD_00567 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IAFDNKHD_00568 2.8e-224 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
IAFDNKHD_00569 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IAFDNKHD_00570 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00571 1.6e-166 moeB 2.7.7.73, 2.7.7.80 H ThiF family
IAFDNKHD_00572 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAFDNKHD_00573 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
IAFDNKHD_00574 2.6e-33 narJ C nitrate reductase molybdenum cofactor assembly chaperone
IAFDNKHD_00575 1.1e-50 narJ C nitrate reductase molybdenum cofactor assembly chaperone
IAFDNKHD_00576 9.6e-129 narI 1.7.5.1 C Nitrate reductase
IAFDNKHD_00577 5.6e-110 EG EamA-like transporter family
IAFDNKHD_00578 7.8e-10 EG EamA-like transporter family
IAFDNKHD_00579 9.4e-118 L Integrase
IAFDNKHD_00580 3e-156 rssA S Phospholipase, patatin family
IAFDNKHD_00582 2.1e-276 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IAFDNKHD_00583 4.3e-236 L Transposase
IAFDNKHD_00585 1.3e-201 xerS L Belongs to the 'phage' integrase family
IAFDNKHD_00587 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IAFDNKHD_00588 4.7e-76 marR K Transcriptional regulator, MarR family
IAFDNKHD_00589 1.8e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAFDNKHD_00590 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAFDNKHD_00591 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IAFDNKHD_00592 1.2e-124 IQ reductase
IAFDNKHD_00593 1.4e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IAFDNKHD_00594 7.6e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IAFDNKHD_00595 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IAFDNKHD_00596 1.6e-255 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IAFDNKHD_00597 8.4e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAFDNKHD_00598 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IAFDNKHD_00599 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IAFDNKHD_00604 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00609 1.1e-200 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_00610 9.4e-12 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00611 4.5e-219 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00612 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00613 1e-111 frnE Q DSBA-like thioredoxin domain
IAFDNKHD_00614 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00615 4e-79 I alpha/beta hydrolase fold
IAFDNKHD_00616 8.5e-20 K Helix-turn-helix XRE-family like proteins
IAFDNKHD_00617 4.3e-35 S Phage derived protein Gp49-like (DUF891)
IAFDNKHD_00619 8.9e-41 yrvD S Pfam:DUF1049
IAFDNKHD_00620 9.6e-152 3.1.3.102, 3.1.3.104 S hydrolase
IAFDNKHD_00621 2.1e-90 ntd 2.4.2.6 F Nucleoside
IAFDNKHD_00622 2e-18
IAFDNKHD_00623 2.6e-163 S Alpha/beta hydrolase of unknown function (DUF915)
IAFDNKHD_00624 6.2e-114 yviA S Protein of unknown function (DUF421)
IAFDNKHD_00625 7e-72 S Protein of unknown function (DUF3290)
IAFDNKHD_00626 2.3e-41 ybaN S Protein of unknown function (DUF454)
IAFDNKHD_00627 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAFDNKHD_00628 1.6e-157 endA V DNA/RNA non-specific endonuclease
IAFDNKHD_00629 6.6e-254 yifK E Amino acid permease
IAFDNKHD_00631 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAFDNKHD_00632 2.3e-229 N Uncharacterized conserved protein (DUF2075)
IAFDNKHD_00633 4.3e-121 S SNARE associated Golgi protein
IAFDNKHD_00634 0.0 uvrA3 L excinuclease ABC, A subunit
IAFDNKHD_00635 5.9e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAFDNKHD_00636 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAFDNKHD_00637 5.4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAFDNKHD_00638 1.1e-144 S DUF218 domain
IAFDNKHD_00639 0.0 ubiB S ABC1 family
IAFDNKHD_00640 7.2e-245 yhdP S Transporter associated domain
IAFDNKHD_00641 5.5e-74 copY K Copper transport repressor CopY TcrY
IAFDNKHD_00642 1.3e-241 EGP Major facilitator Superfamily
IAFDNKHD_00643 1.1e-72 yeaL S UPF0756 membrane protein
IAFDNKHD_00644 4.9e-76 yphH S Cupin domain
IAFDNKHD_00645 1.5e-80 C Flavodoxin
IAFDNKHD_00646 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00647 3e-159 K LysR substrate binding domain protein
IAFDNKHD_00648 1.3e-165 1.1.1.346 C Aldo keto reductase
IAFDNKHD_00649 8.7e-71 XK27_08635 S UPF0210 protein
IAFDNKHD_00650 2.2e-72 XK27_08635 S UPF0210 protein
IAFDNKHD_00651 2.6e-65 XK27_08635 S UPF0210 protein
IAFDNKHD_00652 1.5e-94 K Acetyltransferase (GNAT) domain
IAFDNKHD_00653 8.1e-154 S Alpha beta hydrolase
IAFDNKHD_00654 1.8e-156 gspA M family 8
IAFDNKHD_00655 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IAFDNKHD_00656 1.5e-89
IAFDNKHD_00657 9.3e-161 degV S EDD domain protein, DegV family
IAFDNKHD_00658 2.1e-106 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAFDNKHD_00659 0.0 FbpA K Fibronectin-binding protein
IAFDNKHD_00660 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IAFDNKHD_00661 3.6e-207 carA 6.3.5.5 F Belongs to the CarA family
IAFDNKHD_00662 1.5e-156 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IAFDNKHD_00663 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IAFDNKHD_00664 1.5e-65 esbA S Family of unknown function (DUF5322)
IAFDNKHD_00665 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
IAFDNKHD_00666 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IAFDNKHD_00667 3e-81 F Belongs to the NrdI family
IAFDNKHD_00668 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IAFDNKHD_00669 3.2e-101 ypsA S Belongs to the UPF0398 family
IAFDNKHD_00670 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IAFDNKHD_00671 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IAFDNKHD_00672 1.3e-160 EG EamA-like transporter family
IAFDNKHD_00673 8.1e-123 dnaD L DnaD domain protein
IAFDNKHD_00674 6.9e-87 ypmB S Protein conserved in bacteria
IAFDNKHD_00675 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IAFDNKHD_00676 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IAFDNKHD_00677 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IAFDNKHD_00678 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IAFDNKHD_00679 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IAFDNKHD_00680 2.5e-86 S Protein of unknown function (DUF1440)
IAFDNKHD_00681 7e-122 L Transposase
IAFDNKHD_00682 5.1e-139 L Bacterial dnaA protein
IAFDNKHD_00683 5.8e-230 L Integrase core domain
IAFDNKHD_00684 5.6e-107 L Transposase
IAFDNKHD_00685 0.0 rafA 3.2.1.22 G alpha-galactosidase
IAFDNKHD_00686 5.7e-186 galR K Periplasmic binding protein-like domain
IAFDNKHD_00687 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IAFDNKHD_00688 6.2e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IAFDNKHD_00689 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
IAFDNKHD_00690 4e-148 f42a O Band 7 protein
IAFDNKHD_00691 2.7e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IAFDNKHD_00692 2.7e-154 yitU 3.1.3.104 S hydrolase
IAFDNKHD_00693 2.7e-38 S Cytochrome B5
IAFDNKHD_00694 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00695 5.7e-115 nreC K PFAM regulatory protein LuxR
IAFDNKHD_00696 2.6e-158 hipB K Helix-turn-helix
IAFDNKHD_00697 2.8e-57 yitW S Iron-sulfur cluster assembly protein
IAFDNKHD_00698 3.6e-271 sufB O assembly protein SufB
IAFDNKHD_00699 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
IAFDNKHD_00700 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAFDNKHD_00701 5.1e-240 sufD O FeS assembly protein SufD
IAFDNKHD_00702 1.9e-144 sufC O FeS assembly ATPase SufC
IAFDNKHD_00703 2.8e-31 feoA P FeoA domain
IAFDNKHD_00704 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IAFDNKHD_00705 4e-259 S Uncharacterised protein family (UPF0236)
IAFDNKHD_00706 2.3e-35 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IAFDNKHD_00707 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00708 5.8e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IAFDNKHD_00709 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAFDNKHD_00710 6.7e-60 ydiI Q Thioesterase superfamily
IAFDNKHD_00711 7.1e-109 yvrI K sigma factor activity
IAFDNKHD_00712 9.8e-206 G Transporter, major facilitator family protein
IAFDNKHD_00713 0.0 S Bacterial membrane protein YfhO
IAFDNKHD_00714 3.3e-103 T Ion transport 2 domain protein
IAFDNKHD_00715 9.9e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IAFDNKHD_00716 4.8e-142 L transposase, IS605 OrfB family
IAFDNKHD_00717 1.1e-22 L Integrase core domain
IAFDNKHD_00718 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00719 3.9e-201 L Integrase core domain
IAFDNKHD_00720 5.1e-139 L Bacterial dnaA protein
IAFDNKHD_00721 3.8e-53 L transposase, IS605 OrfB family
IAFDNKHD_00722 1.1e-59 L PFAM transposase IS200-family protein
IAFDNKHD_00724 0.0 L PLD-like domain
IAFDNKHD_00725 1e-33 3.2.1.17 LO Uncharacterized conserved protein (DUF2075)
IAFDNKHD_00726 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00727 1e-66 L Uncharacterized conserved protein (DUF2075)
IAFDNKHD_00728 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00729 7e-57 yhaI S Protein of unknown function (DUF805)
IAFDNKHD_00730 2.2e-44
IAFDNKHD_00731 2.4e-22
IAFDNKHD_00732 5.4e-20
IAFDNKHD_00733 2.9e-96 K Acetyltransferase (GNAT) domain
IAFDNKHD_00734 3e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IAFDNKHD_00735 1.5e-231 gntT EG Gluconate
IAFDNKHD_00736 2.1e-180 K Transcriptional regulator, LacI family
IAFDNKHD_00737 3.7e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IAFDNKHD_00738 2.6e-92
IAFDNKHD_00739 6.1e-25
IAFDNKHD_00740 6.9e-60 asp S Asp23 family, cell envelope-related function
IAFDNKHD_00741 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00742 1.6e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IAFDNKHD_00744 1.1e-25
IAFDNKHD_00745 2.7e-67 yqkB S Belongs to the HesB IscA family
IAFDNKHD_00746 6.3e-265 L PFAM Integrase catalytic region
IAFDNKHD_00747 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
IAFDNKHD_00748 8.1e-79 F NUDIX domain
IAFDNKHD_00749 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IAFDNKHD_00750 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IAFDNKHD_00751 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IAFDNKHD_00752 2.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
IAFDNKHD_00753 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAFDNKHD_00754 2.1e-160 dprA LU DNA protecting protein DprA
IAFDNKHD_00755 5.1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAFDNKHD_00756 5.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IAFDNKHD_00757 4.4e-35 yozE S Belongs to the UPF0346 family
IAFDNKHD_00758 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IAFDNKHD_00759 2.4e-167 ypmR E lipolytic protein G-D-S-L family
IAFDNKHD_00760 4.9e-151 DegV S EDD domain protein, DegV family
IAFDNKHD_00761 1.9e-110 hlyIII S protein, hemolysin III
IAFDNKHD_00762 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAFDNKHD_00763 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IAFDNKHD_00764 0.0 yfmR S ABC transporter, ATP-binding protein
IAFDNKHD_00765 8.2e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IAFDNKHD_00766 5.3e-200 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_00767 1.4e-234 S Tetratricopeptide repeat protein
IAFDNKHD_00768 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IAFDNKHD_00769 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IAFDNKHD_00770 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
IAFDNKHD_00771 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IAFDNKHD_00772 2.5e-13 M Lysin motif
IAFDNKHD_00773 8.4e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IAFDNKHD_00774 7.5e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
IAFDNKHD_00775 3.2e-197 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_00776 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00777 5.5e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IAFDNKHD_00778 1e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IAFDNKHD_00779 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAFDNKHD_00780 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAFDNKHD_00781 5.3e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IAFDNKHD_00782 2.9e-162 xerD D recombinase XerD
IAFDNKHD_00783 3.3e-166 cvfB S S1 domain
IAFDNKHD_00784 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IAFDNKHD_00785 0.0 dnaE 2.7.7.7 L DNA polymerase
IAFDNKHD_00786 2e-29 S Protein of unknown function (DUF2929)
IAFDNKHD_00787 2.8e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IAFDNKHD_00788 1.1e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAFDNKHD_00789 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
IAFDNKHD_00790 2.4e-220 patA 2.6.1.1 E Aminotransferase
IAFDNKHD_00791 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IAFDNKHD_00792 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IAFDNKHD_00793 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IAFDNKHD_00794 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IAFDNKHD_00795 3.8e-145 recO L Involved in DNA repair and RecF pathway recombination
IAFDNKHD_00796 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAFDNKHD_00797 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IAFDNKHD_00798 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IAFDNKHD_00799 3.2e-181 phoH T phosphate starvation-inducible protein PhoH
IAFDNKHD_00800 1.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IAFDNKHD_00801 1.5e-82 bioY S BioY family
IAFDNKHD_00802 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_00803 6e-263 argH 4.3.2.1 E argininosuccinate lyase
IAFDNKHD_00804 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IAFDNKHD_00805 3.7e-96 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IAFDNKHD_00806 7.8e-73 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IAFDNKHD_00807 8.6e-70 yqeY S YqeY-like protein
IAFDNKHD_00808 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IAFDNKHD_00809 1.1e-262 glnPH2 P ABC transporter permease
IAFDNKHD_00810 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAFDNKHD_00811 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IAFDNKHD_00812 4.6e-165 yniA G Phosphotransferase enzyme family
IAFDNKHD_00813 1.9e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IAFDNKHD_00814 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAFDNKHD_00815 9.4e-50
IAFDNKHD_00816 9.7e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IAFDNKHD_00817 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
IAFDNKHD_00818 7.5e-58
IAFDNKHD_00819 1.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IAFDNKHD_00821 6.3e-146 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IAFDNKHD_00822 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00823 5.2e-47 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IAFDNKHD_00824 2e-274 pipD E Dipeptidase
IAFDNKHD_00825 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_00826 3.9e-237 L Transposase
IAFDNKHD_00827 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IAFDNKHD_00828 9.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IAFDNKHD_00829 0.0 dnaK O Heat shock 70 kDa protein
IAFDNKHD_00830 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IAFDNKHD_00831 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IAFDNKHD_00832 2.9e-63
IAFDNKHD_00833 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IAFDNKHD_00834 2.7e-163 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAFDNKHD_00835 6.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAFDNKHD_00836 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IAFDNKHD_00837 1.3e-48 ylxQ J ribosomal protein
IAFDNKHD_00838 1e-44 ylxR K Protein of unknown function (DUF448)
IAFDNKHD_00839 1.4e-215 nusA K Participates in both transcription termination and antitermination
IAFDNKHD_00840 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
IAFDNKHD_00841 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAFDNKHD_00842 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IAFDNKHD_00843 4.1e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IAFDNKHD_00844 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
IAFDNKHD_00845 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAFDNKHD_00846 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IAFDNKHD_00847 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IAFDNKHD_00848 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IAFDNKHD_00849 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
IAFDNKHD_00850 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFDNKHD_00851 7.1e-49 yazA L GIY-YIG catalytic domain protein
IAFDNKHD_00852 3.5e-140 yabB 2.1.1.223 L Methyltransferase small domain
IAFDNKHD_00853 1.6e-117 plsC 2.3.1.51 I Acyltransferase
IAFDNKHD_00854 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
IAFDNKHD_00855 1.3e-35 ynzC S UPF0291 protein
IAFDNKHD_00856 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAFDNKHD_00857 1.3e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IAFDNKHD_00858 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAFDNKHD_00859 5.6e-261 S Uncharacterised protein family (UPF0236)
IAFDNKHD_00863 4.1e-55
IAFDNKHD_00865 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00866 6.2e-99 S D5 N terminal like
IAFDNKHD_00867 3.1e-51 S Bifunctional DNA primase/polymerase, N-terminal
IAFDNKHD_00869 8.5e-08
IAFDNKHD_00872 4e-21 S Helix-turn-helix domain
IAFDNKHD_00873 1e-16 K Transcriptional regulator
IAFDNKHD_00874 1e-09 M LysM domain
IAFDNKHD_00875 1.9e-134 L Belongs to the 'phage' integrase family
IAFDNKHD_00876 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_00877 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00878 4.3e-88
IAFDNKHD_00879 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAFDNKHD_00880 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IAFDNKHD_00881 5.5e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IAFDNKHD_00882 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IAFDNKHD_00883 4.8e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IAFDNKHD_00884 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IAFDNKHD_00885 7.6e-09
IAFDNKHD_00886 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00887 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IAFDNKHD_00888 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
IAFDNKHD_00889 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IAFDNKHD_00890 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IAFDNKHD_00891 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAFDNKHD_00892 7.1e-164 S Tetratricopeptide repeat
IAFDNKHD_00893 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAFDNKHD_00894 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAFDNKHD_00895 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
IAFDNKHD_00896 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
IAFDNKHD_00897 0.0 comEC S Competence protein ComEC
IAFDNKHD_00898 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
IAFDNKHD_00899 5.8e-80 comEA L Competence protein ComEA
IAFDNKHD_00900 1.9e-197 ylbL T Belongs to the peptidase S16 family
IAFDNKHD_00901 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IAFDNKHD_00902 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IAFDNKHD_00903 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IAFDNKHD_00904 7.7e-222 ftsW D Belongs to the SEDS family
IAFDNKHD_00905 3.5e-196 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_00906 0.0 typA T GTP-binding protein TypA
IAFDNKHD_00907 1.3e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IAFDNKHD_00908 1.9e-46 yktA S Belongs to the UPF0223 family
IAFDNKHD_00909 1.2e-193 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_00910 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_00911 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
IAFDNKHD_00912 1.3e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IAFDNKHD_00913 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IAFDNKHD_00914 1.3e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IAFDNKHD_00915 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IAFDNKHD_00916 5.3e-78
IAFDNKHD_00917 9.8e-32 ykzG S Belongs to the UPF0356 family
IAFDNKHD_00918 4.3e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
IAFDNKHD_00919 1.3e-28
IAFDNKHD_00920 3.8e-130 mltD CBM50 M NlpC P60 family protein
IAFDNKHD_00922 2.2e-57
IAFDNKHD_00923 2.1e-260 S Uncharacterised protein family (UPF0236)
IAFDNKHD_00924 3.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IAFDNKHD_00925 1.1e-218 EG GntP family permease
IAFDNKHD_00926 8.5e-84 KT Putative sugar diacid recognition
IAFDNKHD_00927 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAFDNKHD_00928 7.7e-219 patA 2.6.1.1 E Aminotransferase
IAFDNKHD_00929 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IAFDNKHD_00930 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAFDNKHD_00931 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IAFDNKHD_00932 2.4e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IAFDNKHD_00933 1.3e-57 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IAFDNKHD_00934 4.4e-178 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IAFDNKHD_00935 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
IAFDNKHD_00936 1.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IAFDNKHD_00937 5.8e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAFDNKHD_00938 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IAFDNKHD_00939 1.3e-117 S Repeat protein
IAFDNKHD_00940 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IAFDNKHD_00941 5.3e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IAFDNKHD_00942 7.5e-58 XK27_04120 S Putative amino acid metabolism
IAFDNKHD_00943 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
IAFDNKHD_00944 5.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAFDNKHD_00946 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IAFDNKHD_00947 4.2e-32 cspA K Cold shock protein
IAFDNKHD_00948 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAFDNKHD_00949 1e-35 divIVA D DivIVA domain protein
IAFDNKHD_00950 5.4e-144 ylmH S S4 domain protein
IAFDNKHD_00951 8.7e-29 yggT S YGGT family
IAFDNKHD_00952 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IAFDNKHD_00953 7.8e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAFDNKHD_00954 3.1e-170 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IAFDNKHD_00955 6.4e-58 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IAFDNKHD_00956 7.9e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IAFDNKHD_00957 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAFDNKHD_00958 1.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAFDNKHD_00959 4.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAFDNKHD_00960 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IAFDNKHD_00961 1.3e-55 ftsL D Cell division protein FtsL
IAFDNKHD_00962 1.3e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IAFDNKHD_00963 3.1e-77 mraZ K Belongs to the MraZ family
IAFDNKHD_00964 1.9e-56
IAFDNKHD_00965 1.2e-10 S Protein of unknown function (DUF4044)
IAFDNKHD_00966 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IAFDNKHD_00967 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IAFDNKHD_00968 1e-159 rrmA 2.1.1.187 H Methyltransferase
IAFDNKHD_00969 6.6e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IAFDNKHD_00970 4.1e-264 L PFAM Integrase catalytic region
IAFDNKHD_00971 4.2e-217 L Transposase IS66 family
IAFDNKHD_00972 4e-276 L Transposase IS66 family
IAFDNKHD_00973 9e-62 XK27_01125 L PFAM IS66 Orf2 family protein
IAFDNKHD_00975 5.5e-54 L Transposase IS66 family
IAFDNKHD_00976 6e-66 XK27_01125 L PFAM IS66 Orf2 family protein
IAFDNKHD_00980 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00981 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IAFDNKHD_00982 5.1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAFDNKHD_00983 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
IAFDNKHD_00984 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_00985 3.1e-113 yjbH Q Thioredoxin
IAFDNKHD_00986 6.8e-267 pipD E Dipeptidase
IAFDNKHD_00987 1.8e-195 coiA 3.6.4.12 S Competence protein
IAFDNKHD_00988 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IAFDNKHD_00989 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IAFDNKHD_00990 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IAFDNKHD_00991 2.5e-294 L Transposase IS66 family
IAFDNKHD_00992 5.1e-139 L Bacterial dnaA protein
IAFDNKHD_00993 1.2e-230 L Integrase core domain
IAFDNKHD_00994 2e-49 XK27_01125 L PFAM IS66 Orf2 family protein
IAFDNKHD_01017 1.6e-109 dedA S SNARE-like domain protein
IAFDNKHD_01018 2.8e-101 S Protein of unknown function (DUF1461)
IAFDNKHD_01019 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IAFDNKHD_01020 6.6e-93 yutD S Protein of unknown function (DUF1027)
IAFDNKHD_01021 4.7e-111 S Calcineurin-like phosphoesterase
IAFDNKHD_01022 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAFDNKHD_01023 2.1e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
IAFDNKHD_01024 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_01026 1e-67
IAFDNKHD_01027 3.2e-41
IAFDNKHD_01028 4.1e-77 NU general secretion pathway protein
IAFDNKHD_01029 7.1e-47 comGC U competence protein ComGC
IAFDNKHD_01030 3e-182 comGB NU type II secretion system
IAFDNKHD_01031 1.3e-182 comGA NU Type II IV secretion system protein
IAFDNKHD_01032 5.9e-132 yebC K Transcriptional regulatory protein
IAFDNKHD_01033 1e-132
IAFDNKHD_01034 7.6e-135 ccpA K catabolite control protein A
IAFDNKHD_01035 5.8e-22 ccpA K catabolite control protein A
IAFDNKHD_01036 1.1e-195 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IAFDNKHD_01037 4.3e-16
IAFDNKHD_01038 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IAFDNKHD_01039 6.9e-148 ykuT M mechanosensitive ion channel
IAFDNKHD_01040 1.8e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IAFDNKHD_01041 1.1e-74 ykuL S (CBS) domain
IAFDNKHD_01042 3.8e-93 S Phosphoesterase
IAFDNKHD_01043 9.8e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAFDNKHD_01044 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IAFDNKHD_01045 1.6e-97 yslB S Protein of unknown function (DUF2507)
IAFDNKHD_01046 6.1e-54 trxA O Belongs to the thioredoxin family
IAFDNKHD_01047 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IAFDNKHD_01048 1.6e-86 cvpA S Colicin V production protein
IAFDNKHD_01049 6.1e-48 yrzB S Belongs to the UPF0473 family
IAFDNKHD_01050 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAFDNKHD_01051 4.1e-43 yrzL S Belongs to the UPF0297 family
IAFDNKHD_01052 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAFDNKHD_01053 1.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IAFDNKHD_01054 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IAFDNKHD_01055 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01056 6.2e-31 yajC U Preprotein translocase
IAFDNKHD_01057 2.2e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IAFDNKHD_01058 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IAFDNKHD_01059 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IAFDNKHD_01060 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAFDNKHD_01061 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAFDNKHD_01062 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
IAFDNKHD_01063 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IAFDNKHD_01064 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
IAFDNKHD_01065 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAFDNKHD_01066 1.7e-137 ymfM S Helix-turn-helix domain
IAFDNKHD_01067 2.5e-247 ymfH S Peptidase M16
IAFDNKHD_01068 8.1e-227 ymfF S Peptidase M16 inactive domain protein
IAFDNKHD_01069 1.9e-158 aatB ET ABC transporter substrate-binding protein
IAFDNKHD_01070 4.7e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAFDNKHD_01071 3.2e-102 glnP P ABC transporter permease
IAFDNKHD_01072 8.7e-93 mreD M rod shape-determining protein MreD
IAFDNKHD_01073 3.5e-152 mreC M Involved in formation and maintenance of cell shape
IAFDNKHD_01074 1.7e-179 mreB D cell shape determining protein MreB
IAFDNKHD_01075 8e-122 radC L DNA repair protein
IAFDNKHD_01076 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IAFDNKHD_01077 3.9e-237 L Transposase
IAFDNKHD_01078 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
IAFDNKHD_01079 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IAFDNKHD_01080 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IAFDNKHD_01081 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IAFDNKHD_01082 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
IAFDNKHD_01083 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IAFDNKHD_01084 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAFDNKHD_01085 1.8e-198 iscS2 2.8.1.7 E Aminotransferase class V
IAFDNKHD_01086 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IAFDNKHD_01087 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAFDNKHD_01088 1.3e-72 L PFAM Integrase catalytic region
IAFDNKHD_01089 8.7e-60 L PFAM Integrase catalytic region
IAFDNKHD_01090 8.1e-260 S Uncharacterised protein family (UPF0236)
IAFDNKHD_01091 1.4e-23 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IAFDNKHD_01092 2.2e-199 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IAFDNKHD_01093 6.8e-30 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IAFDNKHD_01094 1.1e-138 S Belongs to the UPF0246 family
IAFDNKHD_01095 1.4e-136 S Membrane
IAFDNKHD_01096 6.8e-74 4.4.1.5 E Glyoxalase
IAFDNKHD_01097 3.2e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01098 4.6e-21
IAFDNKHD_01099 5.1e-84 yueI S Protein of unknown function (DUF1694)
IAFDNKHD_01100 7.9e-233 rarA L recombination factor protein RarA
IAFDNKHD_01101 1.7e-45
IAFDNKHD_01102 4.3e-83 usp6 T universal stress protein
IAFDNKHD_01103 1.4e-203 araR K Transcriptional regulator
IAFDNKHD_01104 7.3e-155 ytbE 1.1.1.346 S Aldo keto reductase
IAFDNKHD_01105 9.2e-29 maa 2.3.1.79 S Maltose O-acetyltransferase
IAFDNKHD_01106 2.2e-50 maa 2.3.1.79 S Maltose O-acetyltransferase
IAFDNKHD_01107 2.2e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IAFDNKHD_01108 1.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IAFDNKHD_01109 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
IAFDNKHD_01110 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IAFDNKHD_01111 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IAFDNKHD_01112 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IAFDNKHD_01113 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_01114 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01115 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01116 1.8e-200 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_01117 1.4e-47 gcvH E glycine cleavage
IAFDNKHD_01118 1.1e-220 rodA D Belongs to the SEDS family
IAFDNKHD_01119 1e-31 S Protein of unknown function (DUF2969)
IAFDNKHD_01120 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IAFDNKHD_01121 1.9e-178 mbl D Cell shape determining protein MreB Mrl
IAFDNKHD_01122 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAFDNKHD_01123 1.3e-33 ywzB S Protein of unknown function (DUF1146)
IAFDNKHD_01124 2.9e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IAFDNKHD_01125 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAFDNKHD_01126 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IAFDNKHD_01127 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IAFDNKHD_01128 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAFDNKHD_01129 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IAFDNKHD_01130 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAFDNKHD_01131 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
IAFDNKHD_01132 5.9e-233 pyrP F Permease
IAFDNKHD_01133 4.4e-130 yibF S overlaps another CDS with the same product name
IAFDNKHD_01134 1.7e-191 yibE S overlaps another CDS with the same product name
IAFDNKHD_01135 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAFDNKHD_01136 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAFDNKHD_01137 1.1e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAFDNKHD_01138 4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IAFDNKHD_01139 6.6e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IAFDNKHD_01140 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAFDNKHD_01141 6e-108 tdk 2.7.1.21 F thymidine kinase
IAFDNKHD_01142 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_01143 6.4e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
IAFDNKHD_01144 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
IAFDNKHD_01145 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01146 1.8e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01147 1.4e-222 arcD U Amino acid permease
IAFDNKHD_01148 3.2e-259 E Arginine ornithine antiporter
IAFDNKHD_01149 2.7e-79 argR K Regulates arginine biosynthesis genes
IAFDNKHD_01150 3.1e-218 arcA 3.5.3.6 E Arginine
IAFDNKHD_01151 3.5e-183 ampC V Beta-lactamase
IAFDNKHD_01152 4.1e-19
IAFDNKHD_01153 1.5e-244 L Transposase
IAFDNKHD_01154 5e-158 M domain protein
IAFDNKHD_01155 1.9e-306 M domain protein
IAFDNKHD_01156 2e-91
IAFDNKHD_01158 3.3e-78 yjcE P Sodium proton antiporter
IAFDNKHD_01159 1.1e-149 yjcE P Sodium proton antiporter
IAFDNKHD_01160 2.3e-56
IAFDNKHD_01162 1.2e-85
IAFDNKHD_01163 0.0 copA 3.6.3.54 P P-type ATPase
IAFDNKHD_01164 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IAFDNKHD_01165 2.9e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IAFDNKHD_01166 4.5e-158 EG EamA-like transporter family
IAFDNKHD_01167 3.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
IAFDNKHD_01168 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAFDNKHD_01169 3.6e-154 KT YcbB domain
IAFDNKHD_01170 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IAFDNKHD_01172 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_01173 1e-25
IAFDNKHD_01174 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
IAFDNKHD_01175 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
IAFDNKHD_01176 4.1e-153 glcU U sugar transport
IAFDNKHD_01177 7.6e-272 yclK 2.7.13.3 T Histidine kinase
IAFDNKHD_01178 1.2e-134 K response regulator
IAFDNKHD_01180 1.3e-76 lytE M Lysin motif
IAFDNKHD_01181 1.1e-147 XK27_02985 S Cof-like hydrolase
IAFDNKHD_01182 1.8e-78 K Transcriptional regulator
IAFDNKHD_01183 0.0 oatA I Acyltransferase
IAFDNKHD_01184 8.4e-42
IAFDNKHD_01185 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IAFDNKHD_01186 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAFDNKHD_01187 1.3e-125 ybbR S YbbR-like protein
IAFDNKHD_01188 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAFDNKHD_01189 3.7e-249 fucP G Major Facilitator Superfamily
IAFDNKHD_01190 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IAFDNKHD_01191 6.1e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAFDNKHD_01192 3e-167 murB 1.3.1.98 M Cell wall formation
IAFDNKHD_01193 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_01194 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
IAFDNKHD_01195 4.4e-76 S PAS domain
IAFDNKHD_01196 2.3e-87 K Acetyltransferase (GNAT) domain
IAFDNKHD_01197 2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IAFDNKHD_01198 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IAFDNKHD_01199 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAFDNKHD_01200 1.4e-104 yxjI
IAFDNKHD_01201 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IAFDNKHD_01202 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IAFDNKHD_01203 5.9e-143 est 3.1.1.1 S Serine aminopeptidase, S33
IAFDNKHD_01204 1.8e-34 secG U Preprotein translocase
IAFDNKHD_01205 3.1e-292 clcA P chloride
IAFDNKHD_01206 1.2e-244 yifK E Amino acid permease
IAFDNKHD_01207 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IAFDNKHD_01208 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IAFDNKHD_01209 1.7e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IAFDNKHD_01210 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IAFDNKHD_01212 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IAFDNKHD_01213 6.6e-63 L PFAM Integrase catalytic region
IAFDNKHD_01214 5.2e-69 L PFAM Integrase catalytic region
IAFDNKHD_01215 8.8e-15
IAFDNKHD_01217 1.5e-169 whiA K May be required for sporulation
IAFDNKHD_01218 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IAFDNKHD_01219 4.6e-160 rapZ S Displays ATPase and GTPase activities
IAFDNKHD_01220 1.6e-244 steT E amino acid
IAFDNKHD_01221 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IAFDNKHD_01222 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IAFDNKHD_01223 6.9e-14
IAFDNKHD_01224 1.9e-115 yfbR S HD containing hydrolase-like enzyme
IAFDNKHD_01225 1.1e-200 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_01226 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IAFDNKHD_01227 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
IAFDNKHD_01228 1.4e-161 aatB ET PFAM extracellular solute-binding protein, family 3
IAFDNKHD_01229 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IAFDNKHD_01230 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IAFDNKHD_01231 7.8e-168 lutA C Cysteine-rich domain
IAFDNKHD_01232 3e-292 lutB C 4Fe-4S dicluster domain
IAFDNKHD_01233 1e-136 yrjD S LUD domain
IAFDNKHD_01234 9e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IAFDNKHD_01235 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IAFDNKHD_01236 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IAFDNKHD_01237 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IAFDNKHD_01238 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IAFDNKHD_01239 7.7e-31 KT PspC domain protein
IAFDNKHD_01240 1.1e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IAFDNKHD_01241 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IAFDNKHD_01242 7.2e-42 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IAFDNKHD_01243 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAFDNKHD_01244 1.1e-93 comFC S Competence protein
IAFDNKHD_01245 1.6e-249 comFA L Helicase C-terminal domain protein
IAFDNKHD_01246 4.3e-107 yvyE 3.4.13.9 S YigZ family
IAFDNKHD_01247 7e-80 L transposase and inactivated derivatives, IS30 family
IAFDNKHD_01248 1.4e-42 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01249 7.4e-50 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01250 1.3e-36 EGP Major facilitator Superfamily
IAFDNKHD_01251 6.1e-153 EGP Major facilitator Superfamily
IAFDNKHD_01252 6.2e-67 rmaI K Transcriptional regulator
IAFDNKHD_01253 2.7e-39
IAFDNKHD_01254 0.0 ydaO E amino acid
IAFDNKHD_01255 1.3e-301 ybeC E amino acid
IAFDNKHD_01256 1.3e-79 S Aminoacyl-tRNA editing domain
IAFDNKHD_01257 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IAFDNKHD_01258 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IAFDNKHD_01260 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IAFDNKHD_01261 0.0 uup S ABC transporter, ATP-binding protein
IAFDNKHD_01262 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAFDNKHD_01263 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
IAFDNKHD_01264 3.6e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IAFDNKHD_01265 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAFDNKHD_01266 3.8e-216 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IAFDNKHD_01267 8e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAFDNKHD_01268 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAFDNKHD_01269 2.9e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IAFDNKHD_01270 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IAFDNKHD_01271 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IAFDNKHD_01272 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IAFDNKHD_01273 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IAFDNKHD_01274 7e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IAFDNKHD_01275 3.8e-134 fat 3.1.2.21 I Acyl-ACP thioesterase
IAFDNKHD_01276 1.9e-153 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IAFDNKHD_01277 3.1e-43 yabA L Involved in initiation control of chromosome replication
IAFDNKHD_01278 2.5e-181 holB 2.7.7.7 L DNA polymerase III
IAFDNKHD_01279 2.9e-51 yaaQ S Cyclic-di-AMP receptor
IAFDNKHD_01280 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAFDNKHD_01281 2.8e-38 S Protein of unknown function (DUF2508)
IAFDNKHD_01282 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAFDNKHD_01283 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IAFDNKHD_01284 7.1e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAFDNKHD_01285 1.3e-229 L transposase, IS605 OrfB family
IAFDNKHD_01286 2.1e-60 L PFAM transposase IS200-family protein
IAFDNKHD_01287 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IAFDNKHD_01288 3.4e-35 nrdH O Glutaredoxin
IAFDNKHD_01289 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAFDNKHD_01290 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAFDNKHD_01291 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IAFDNKHD_01292 1.3e-131 S Putative adhesin
IAFDNKHD_01293 3.2e-83 XK27_06920 S Protein of unknown function (DUF1700)
IAFDNKHD_01294 2.4e-56 K transcriptional regulator PadR family
IAFDNKHD_01295 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IAFDNKHD_01297 3.4e-48
IAFDNKHD_01298 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IAFDNKHD_01299 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAFDNKHD_01300 2.3e-173 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IAFDNKHD_01301 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01303 8e-224 aadAT EK Aminotransferase, class I
IAFDNKHD_01304 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IAFDNKHD_01305 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IAFDNKHD_01306 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
IAFDNKHD_01307 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IAFDNKHD_01308 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IAFDNKHD_01309 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAFDNKHD_01310 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IAFDNKHD_01311 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAFDNKHD_01312 1.1e-204 yacL S domain protein
IAFDNKHD_01313 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IAFDNKHD_01314 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IAFDNKHD_01315 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
IAFDNKHD_01316 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAFDNKHD_01317 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
IAFDNKHD_01318 6.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IAFDNKHD_01319 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAFDNKHD_01320 1.1e-119 tcyB E ABC transporter
IAFDNKHD_01321 2.5e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IAFDNKHD_01322 1.3e-167 I alpha/beta hydrolase fold
IAFDNKHD_01323 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAFDNKHD_01324 0.0 S Bacterial membrane protein, YfhO
IAFDNKHD_01325 1.7e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IAFDNKHD_01326 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IAFDNKHD_01327 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01329 2.9e-81 ydcK S Belongs to the SprT family
IAFDNKHD_01330 0.0 yhgF K Tex-like protein N-terminal domain protein
IAFDNKHD_01331 2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IAFDNKHD_01332 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAFDNKHD_01333 5.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
IAFDNKHD_01334 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IAFDNKHD_01335 1e-301 aspT P Predicted Permease Membrane Region
IAFDNKHD_01336 8.5e-249 EGP Major facilitator Superfamily
IAFDNKHD_01337 8.5e-111
IAFDNKHD_01340 5.9e-149 yjjH S Calcineurin-like phosphoesterase
IAFDNKHD_01341 1.3e-263 dtpT U amino acid peptide transporter
IAFDNKHD_01345 1.5e-294 L Transposase IS66 family
IAFDNKHD_01346 2.7e-66 XK27_01125 L PFAM IS66 Orf2 family protein
IAFDNKHD_01348 2.6e-122 L Integrase core domain
IAFDNKHD_01349 1.4e-109 L Bacterial dnaA protein
IAFDNKHD_01353 1.9e-84
IAFDNKHD_01354 3.5e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01355 1.3e-168 L Belongs to the 'phage' integrase family
IAFDNKHD_01356 3.1e-19 S Excisionase from transposon Tn916
IAFDNKHD_01359 3.3e-133
IAFDNKHD_01360 1.1e-12 S Helix-turn-helix domain
IAFDNKHD_01362 1e-78 L Resolvase, N terminal domain
IAFDNKHD_01364 2.9e-09 L Resolvase, N terminal domain
IAFDNKHD_01365 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01366 3.4e-11 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
IAFDNKHD_01370 5.2e-119 L hmm pf00665
IAFDNKHD_01371 1.3e-94 L Helix-turn-helix domain
IAFDNKHD_01372 3.2e-197 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_01373 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01374 1.6e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAFDNKHD_01375 5.4e-48 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAFDNKHD_01376 3.7e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IAFDNKHD_01377 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAFDNKHD_01378 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IAFDNKHD_01379 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAFDNKHD_01380 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IAFDNKHD_01381 2.4e-251 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IAFDNKHD_01382 9.8e-67 yabR J RNA binding
IAFDNKHD_01383 8.1e-55 divIC D Septum formation initiator
IAFDNKHD_01384 6.2e-39 yabO J S4 domain protein
IAFDNKHD_01385 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAFDNKHD_01386 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IAFDNKHD_01387 6.9e-113 S (CBS) domain
IAFDNKHD_01388 6.4e-145 tesE Q hydratase
IAFDNKHD_01389 2.3e-242 codA 3.5.4.1 F cytosine deaminase
IAFDNKHD_01390 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
IAFDNKHD_01391 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
IAFDNKHD_01392 3.4e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAFDNKHD_01393 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IAFDNKHD_01395 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAFDNKHD_01396 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
IAFDNKHD_01397 1.1e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAFDNKHD_01398 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IAFDNKHD_01399 4.9e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
IAFDNKHD_01400 1.5e-152 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAFDNKHD_01401 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IAFDNKHD_01402 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IAFDNKHD_01403 7.5e-158 htpX O Belongs to the peptidase M48B family
IAFDNKHD_01404 7e-93 lemA S LemA family
IAFDNKHD_01405 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAFDNKHD_01406 2.7e-120 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IAFDNKHD_01407 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IAFDNKHD_01408 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IAFDNKHD_01409 8.8e-158 3.2.1.55 GH51 G Right handed beta helix region
IAFDNKHD_01410 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IAFDNKHD_01411 7.3e-116 srtA 3.4.22.70 M sortase family
IAFDNKHD_01412 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
IAFDNKHD_01413 1.4e-133 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAFDNKHD_01414 3.7e-62 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAFDNKHD_01415 4.6e-41 rpmE2 J Ribosomal protein L31
IAFDNKHD_01416 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAFDNKHD_01417 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IAFDNKHD_01418 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IAFDNKHD_01419 5.2e-53 ywiB S Domain of unknown function (DUF1934)
IAFDNKHD_01420 2.4e-228 L transposase, IS605 OrfB family
IAFDNKHD_01421 4.7e-60 L PFAM transposase IS200-family protein
IAFDNKHD_01422 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IAFDNKHD_01423 1e-270 ywfO S HD domain protein
IAFDNKHD_01424 6.1e-146 yxeH S hydrolase
IAFDNKHD_01425 9e-48
IAFDNKHD_01426 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAFDNKHD_01427 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IAFDNKHD_01428 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IAFDNKHD_01429 4.7e-127 znuB U ABC 3 transport family
IAFDNKHD_01430 2.2e-122 fhuC P ABC transporter
IAFDNKHD_01431 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
IAFDNKHD_01432 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01433 6.9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IAFDNKHD_01434 6.8e-37 veg S Biofilm formation stimulator VEG
IAFDNKHD_01435 1e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IAFDNKHD_01436 1.2e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAFDNKHD_01437 1e-153 tatD L hydrolase, TatD family
IAFDNKHD_01438 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAFDNKHD_01439 1.2e-160 yunF F Protein of unknown function DUF72
IAFDNKHD_01441 4e-130 cobB K SIR2 family
IAFDNKHD_01442 8.6e-176
IAFDNKHD_01443 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IAFDNKHD_01444 4.6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IAFDNKHD_01445 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAFDNKHD_01446 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IAFDNKHD_01447 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
IAFDNKHD_01448 0.0 helD 3.6.4.12 L DNA helicase
IAFDNKHD_01449 4.5e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IAFDNKHD_01451 2e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAFDNKHD_01452 5.7e-264 yfnA E amino acid
IAFDNKHD_01453 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAFDNKHD_01454 8.9e-41 1.3.5.4 S FMN binding
IAFDNKHD_01455 8.3e-221 norA EGP Major facilitator Superfamily
IAFDNKHD_01456 5.3e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IAFDNKHD_01457 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01458 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
IAFDNKHD_01459 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAFDNKHD_01460 3.1e-103 metI P ABC transporter permease
IAFDNKHD_01461 1.9e-156 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IAFDNKHD_01462 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01463 1.5e-15 clcA P chloride
IAFDNKHD_01464 1.2e-95 clcA P chloride
IAFDNKHD_01465 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IAFDNKHD_01466 1.9e-102 proW P ABC transporter, permease protein
IAFDNKHD_01467 6.5e-142 proV E ABC transporter, ATP-binding protein
IAFDNKHD_01468 2.4e-108 proWZ P ABC transporter permease
IAFDNKHD_01469 7e-164 proX M ABC transporter, substrate-binding protein, QAT family
IAFDNKHD_01470 8.4e-73 K Transcriptional regulator
IAFDNKHD_01471 1.9e-51 1.6.5.2 GM NAD(P)H-binding
IAFDNKHD_01472 1.6e-35 1.6.5.2 GM NAD(P)H-binding
IAFDNKHD_01474 1.1e-220 5.4.2.7 G Metalloenzyme superfamily
IAFDNKHD_01475 2.5e-311 cadA P P-type ATPase
IAFDNKHD_01476 1.3e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IAFDNKHD_01477 2.3e-125
IAFDNKHD_01478 2.6e-52 S Sugar efflux transporter for intercellular exchange
IAFDNKHD_01479 8.5e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IAFDNKHD_01481 0.0 L Helicase C-terminal domain protein
IAFDNKHD_01482 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
IAFDNKHD_01483 1.8e-178 S Aldo keto reductase
IAFDNKHD_01485 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IAFDNKHD_01486 1.4e-26 psiE S Phosphate-starvation-inducible E
IAFDNKHD_01487 1.2e-97 ydeN S Serine hydrolase
IAFDNKHD_01489 1.1e-181 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAFDNKHD_01490 1.2e-253 nhaC C Na H antiporter NhaC
IAFDNKHD_01491 1.1e-36 S Cytochrome b5-like Heme/Steroid binding domain
IAFDNKHD_01492 7.3e-107 ywnB S NAD(P)H-binding
IAFDNKHD_01493 1.2e-114 L PFAM Integrase catalytic region
IAFDNKHD_01496 3.5e-175 MA20_14895 S Conserved hypothetical protein 698
IAFDNKHD_01497 1.9e-145 K LysR substrate binding domain
IAFDNKHD_01498 6.4e-96 V VanZ like family
IAFDNKHD_01500 6e-26
IAFDNKHD_01502 5.2e-146 L Transposase and inactivated derivatives IS30 family
IAFDNKHD_01504 8.7e-113 fic S Fic/DOC family
IAFDNKHD_01505 2.1e-129 L Belongs to the 'phage' integrase family
IAFDNKHD_01506 4e-19
IAFDNKHD_01509 2.2e-153
IAFDNKHD_01511 1.6e-76 L Resolvase, N terminal domain
IAFDNKHD_01512 2.2e-10 L Resolvase, N terminal domain
IAFDNKHD_01513 6.3e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAFDNKHD_01516 6e-50 ebh D nuclear chromosome segregation
IAFDNKHD_01517 9.8e-15 K Cro/C1-type HTH DNA-binding domain
IAFDNKHD_01518 2e-263 L PFAM Integrase catalytic region
IAFDNKHD_01519 2e-184 S PglZ domain
IAFDNKHD_01520 2.6e-49 doc S Fic/DOC family
IAFDNKHD_01522 2.8e-296 2.1.1.72 LV Eco57I restriction-modification methylase
IAFDNKHD_01523 1e-221 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
IAFDNKHD_01524 1.7e-49 S Domain of unknown function (DUF1788)
IAFDNKHD_01525 4.4e-45 S Putative inner membrane protein (DUF1819)
IAFDNKHD_01527 6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAFDNKHD_01528 1.8e-166
IAFDNKHD_01529 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAFDNKHD_01530 5.2e-259 S Uncharacterised protein family (UPF0236)
IAFDNKHD_01531 6.7e-107 purD 6.3.4.13 F Belongs to the GARS family
IAFDNKHD_01532 3e-128 purD 6.3.4.13 F Belongs to the GARS family
IAFDNKHD_01533 9.6e-247 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IAFDNKHD_01534 1.9e-33 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IAFDNKHD_01535 3.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAFDNKHD_01536 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IAFDNKHD_01537 5.8e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IAFDNKHD_01538 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAFDNKHD_01539 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAFDNKHD_01540 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAFDNKHD_01541 4.4e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IAFDNKHD_01542 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAFDNKHD_01543 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAFDNKHD_01544 4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAFDNKHD_01545 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IAFDNKHD_01546 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IAFDNKHD_01547 1e-83 thrC 4.2.3.1 E Threonine synthase
IAFDNKHD_01548 1.3e-94 thrC 4.2.3.1 E Threonine synthase
IAFDNKHD_01549 2.7e-24 K helix_turn_helix, arabinose operon control protein
IAFDNKHD_01550 2.5e-127 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IAFDNKHD_01551 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IAFDNKHD_01552 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_01553 3.9e-237 L Transposase
IAFDNKHD_01554 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IAFDNKHD_01555 6.6e-174 K AI-2E family transporter
IAFDNKHD_01556 1.2e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IAFDNKHD_01557 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAFDNKHD_01558 1.4e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IAFDNKHD_01559 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAFDNKHD_01560 5.1e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IAFDNKHD_01561 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IAFDNKHD_01562 7.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IAFDNKHD_01563 1.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IAFDNKHD_01564 5.3e-132 K LysR substrate binding domain
IAFDNKHD_01565 1.6e-52 azlD S branched-chain amino acid
IAFDNKHD_01566 2.7e-139 azlC E AzlC protein
IAFDNKHD_01567 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
IAFDNKHD_01568 3.8e-125 K response regulator
IAFDNKHD_01569 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IAFDNKHD_01570 4e-170 deoR K sugar-binding domain protein
IAFDNKHD_01571 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IAFDNKHD_01572 3.2e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IAFDNKHD_01573 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAFDNKHD_01574 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IAFDNKHD_01575 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
IAFDNKHD_01576 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IAFDNKHD_01577 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
IAFDNKHD_01578 5e-154 spo0J K Belongs to the ParB family
IAFDNKHD_01579 3.6e-140 soj D Sporulation initiation inhibitor
IAFDNKHD_01580 1.5e-143 noc K Belongs to the ParB family
IAFDNKHD_01581 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IAFDNKHD_01582 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
IAFDNKHD_01583 6.6e-170 rihC 3.2.2.1 F Nucleoside
IAFDNKHD_01584 1.3e-218 nupG F Nucleoside transporter
IAFDNKHD_01585 1.6e-220 cycA E Amino acid permease
IAFDNKHD_01586 1.9e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAFDNKHD_01587 2.2e-263 glnP P ABC transporter
IAFDNKHD_01588 1.8e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01589 3.6e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAFDNKHD_01590 3.7e-123 L Transposase
IAFDNKHD_01591 1e-75 L Transposase
IAFDNKHD_01592 1.9e-43 L Transposase
IAFDNKHD_01593 3.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IAFDNKHD_01594 2.2e-203 XK27_09615 S reductase
IAFDNKHD_01595 2.4e-101 nqr 1.5.1.36 S reductase
IAFDNKHD_01597 1.7e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAFDNKHD_01598 3.8e-174 K Transcriptional regulator, LacI family
IAFDNKHD_01599 6.1e-260 G Major Facilitator
IAFDNKHD_01600 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IAFDNKHD_01601 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IAFDNKHD_01602 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01603 2.9e-184 G Major Facilitator
IAFDNKHD_01604 1.3e-124 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IAFDNKHD_01605 3.9e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
IAFDNKHD_01606 1.2e-269 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IAFDNKHD_01607 9.9e-267 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IAFDNKHD_01608 8.3e-72
IAFDNKHD_01609 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01610 3.4e-74 K Transcriptional regulator, TetR family
IAFDNKHD_01611 2.1e-12 K Transcriptional regulator, TetR family
IAFDNKHD_01612 1.4e-13 steT_1 E amino acid
IAFDNKHD_01614 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IAFDNKHD_01615 6.9e-83
IAFDNKHD_01616 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAFDNKHD_01617 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IAFDNKHD_01618 1.7e-262 nox C NADH oxidase
IAFDNKHD_01619 3e-87 hmpT S ECF-type riboflavin transporter, S component
IAFDNKHD_01620 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IAFDNKHD_01621 5.9e-168 yvgN C Aldo keto reductase
IAFDNKHD_01622 6.6e-136 puuD S peptidase C26
IAFDNKHD_01623 1.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IAFDNKHD_01624 1.4e-215 yfeO P Voltage gated chloride channel
IAFDNKHD_01625 3.1e-226 sptS 2.7.13.3 T Histidine kinase
IAFDNKHD_01626 3.3e-118 K response regulator
IAFDNKHD_01627 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
IAFDNKHD_01628 1e-71
IAFDNKHD_01629 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IAFDNKHD_01630 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IAFDNKHD_01631 1.1e-256 malT G Major Facilitator
IAFDNKHD_01632 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
IAFDNKHD_01633 4.3e-172 malR K Transcriptional regulator, LacI family
IAFDNKHD_01634 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IAFDNKHD_01635 8.2e-146 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IAFDNKHD_01636 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IAFDNKHD_01637 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAFDNKHD_01638 2e-103 wecD3 K PFAM GCN5-related N-acetyltransferase
IAFDNKHD_01640 0.0 clpL O associated with various cellular activities
IAFDNKHD_01641 7.8e-32
IAFDNKHD_01642 1.2e-214 patA 2.6.1.1 E Aminotransferase
IAFDNKHD_01643 3.2e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFDNKHD_01644 5e-75 osmC O OsmC-like protein
IAFDNKHD_01645 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01646 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IAFDNKHD_01647 2.9e-96 S reductase
IAFDNKHD_01649 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IAFDNKHD_01650 6.5e-179 ABC-SBP S ABC transporter
IAFDNKHD_01651 2.3e-84 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IAFDNKHD_01652 4.2e-217 L transposase IS116 IS110 IS902 family protein
IAFDNKHD_01653 1.6e-214 htrA 3.4.21.107 O serine protease
IAFDNKHD_01654 2.3e-153 vicX 3.1.26.11 S domain protein
IAFDNKHD_01655 7.8e-149 yycI S YycH protein
IAFDNKHD_01656 2.4e-245 yycH S YycH protein
IAFDNKHD_01657 0.0 vicK 2.7.13.3 T Histidine kinase
IAFDNKHD_01658 3.1e-130 K response regulator
IAFDNKHD_01660 7.6e-308 lmrA 3.6.3.44 V ABC transporter
IAFDNKHD_01661 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
IAFDNKHD_01663 7.5e-96 Z012_01130 S Fic/DOC family
IAFDNKHD_01665 6.9e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
IAFDNKHD_01666 9.1e-61
IAFDNKHD_01667 9e-207 yttB EGP Major facilitator Superfamily
IAFDNKHD_01668 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IAFDNKHD_01669 2e-74 rplI J Binds to the 23S rRNA
IAFDNKHD_01670 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IAFDNKHD_01671 2.6e-100 deoR K sugar-binding domain protein
IAFDNKHD_01672 2.4e-74 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IAFDNKHD_01673 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAFDNKHD_01674 2.8e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IAFDNKHD_01675 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IAFDNKHD_01676 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAFDNKHD_01677 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAFDNKHD_01678 6.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAFDNKHD_01679 3.8e-34 yaaA S S4 domain protein YaaA
IAFDNKHD_01680 2e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IAFDNKHD_01681 6.8e-156 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAFDNKHD_01682 1.6e-79 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAFDNKHD_01683 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IAFDNKHD_01684 6e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IAFDNKHD_01685 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IAFDNKHD_01686 6.3e-129 jag S R3H domain protein
IAFDNKHD_01687 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IAFDNKHD_01688 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IAFDNKHD_01689 0.0 asnB 6.3.5.4 E Asparagine synthase
IAFDNKHD_01690 5.8e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAFDNKHD_01691 3.2e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
IAFDNKHD_01692 2.2e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IAFDNKHD_01693 1.5e-91 2.3.1.183 M Acetyltransferase GNAT family
IAFDNKHD_01694 2.3e-190 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01695 4.1e-50 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01696 2.8e-50 S amidohydrolase
IAFDNKHD_01697 3.2e-259 K Aminotransferase class I and II
IAFDNKHD_01698 2.2e-48 azlC E azaleucine resistance protein AzlC
IAFDNKHD_01699 1.3e-84 L PFAM transposase IS200-family protein
IAFDNKHD_01700 4.4e-59 azlC E azaleucine resistance protein AzlC
IAFDNKHD_01701 3.2e-50 azlD E Branched-chain amino acid transport
IAFDNKHD_01702 9.5e-113 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IAFDNKHD_01704 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01705 5.9e-80 S GyrI-like small molecule binding domain
IAFDNKHD_01706 7.3e-13 S GyrI-like small molecule binding domain
IAFDNKHD_01707 7e-104 yhiD S MgtC family
IAFDNKHD_01708 2.7e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IAFDNKHD_01709 4.8e-193 V Beta-lactamase
IAFDNKHD_01710 3.1e-124 L PFAM Integrase catalytic region
IAFDNKHD_01712 5.9e-18 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
IAFDNKHD_01713 1.6e-109 T Transcriptional regulatory protein, C terminal
IAFDNKHD_01714 1.3e-214 T GHKL domain
IAFDNKHD_01715 8.7e-82 S Peptidase propeptide and YPEB domain
IAFDNKHD_01716 1.5e-65 lacA S transferase hexapeptide repeat
IAFDNKHD_01717 2.2e-119 S Alpha beta hydrolase
IAFDNKHD_01718 5.1e-153 tesE Q hydratase
IAFDNKHD_01719 6.6e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IAFDNKHD_01720 2.3e-155 ypuA S Protein of unknown function (DUF1002)
IAFDNKHD_01721 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
IAFDNKHD_01722 2.1e-144 K Transcriptional regulator
IAFDNKHD_01723 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01724 1.3e-160 akr5f 1.1.1.346 S reductase
IAFDNKHD_01725 1.6e-101 qorB 1.6.5.2 GM NmrA-like family
IAFDNKHD_01726 1.9e-59 yneR
IAFDNKHD_01727 2.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
IAFDNKHD_01728 1.9e-37 T EAL domain
IAFDNKHD_01729 7.1e-105 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01730 1.2e-114 L PFAM Integrase catalytic region
IAFDNKHD_01731 3.7e-26 L PFAM Integrase catalytic region
IAFDNKHD_01732 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IAFDNKHD_01733 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
IAFDNKHD_01734 2.3e-24 folT S ECF transporter, substrate-specific component
IAFDNKHD_01735 1.9e-48 K Transcriptional regulator
IAFDNKHD_01736 0.0 pepN 3.4.11.2 E aminopeptidase
IAFDNKHD_01737 6e-109 ylbE GM NAD dependent epimerase dehydratase family protein
IAFDNKHD_01738 3e-256 pepC 3.4.22.40 E aminopeptidase
IAFDNKHD_01739 1.4e-209 EGP Major facilitator Superfamily
IAFDNKHD_01740 1.6e-233
IAFDNKHD_01741 1.2e-82 K Transcriptional regulator, HxlR family
IAFDNKHD_01742 4.1e-107 XK27_02070 S Nitroreductase family
IAFDNKHD_01743 1.8e-50 hxlR K Transcriptional regulator, HxlR family
IAFDNKHD_01744 1.2e-120 GM NmrA-like family
IAFDNKHD_01745 2.1e-260 S Uncharacterised protein family (UPF0236)
IAFDNKHD_01746 9.6e-74 elaA S Gnat family
IAFDNKHD_01747 3.5e-72 L transposase and inactivated derivatives, IS30 family
IAFDNKHD_01748 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01749 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAFDNKHD_01750 8.6e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAFDNKHD_01751 5.1e-238 E amino acid
IAFDNKHD_01752 1.1e-130 npp S type I phosphodiesterase nucleotide pyrophosphatase
IAFDNKHD_01753 6.3e-52 npp S type I phosphodiesterase nucleotide pyrophosphatase
IAFDNKHD_01754 6e-214 yxiO S Vacuole effluxer Atg22 like
IAFDNKHD_01756 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAFDNKHD_01757 6.4e-32
IAFDNKHD_01758 4.2e-264 L PFAM Integrase catalytic region
IAFDNKHD_01759 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
IAFDNKHD_01760 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
IAFDNKHD_01761 1.8e-84 ygfC K transcriptional regulator (TetR family)
IAFDNKHD_01762 4e-166 hrtB V ABC transporter permease
IAFDNKHD_01763 5e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IAFDNKHD_01764 0.0 yhcA V ABC transporter, ATP-binding protein
IAFDNKHD_01765 2.5e-36
IAFDNKHD_01766 9.2e-50 czrA K Transcriptional regulator, ArsR family
IAFDNKHD_01767 2.9e-235 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IAFDNKHD_01768 2.5e-172 scrR K Transcriptional regulator, LacI family
IAFDNKHD_01769 1e-24
IAFDNKHD_01770 2.6e-101
IAFDNKHD_01771 8.9e-215 yttB EGP Major facilitator Superfamily
IAFDNKHD_01772 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
IAFDNKHD_01773 1.6e-67
IAFDNKHD_01774 3.9e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IAFDNKHD_01775 1.2e-260 S Putative peptidoglycan binding domain
IAFDNKHD_01776 1.3e-122 yciB M ErfK YbiS YcfS YnhG
IAFDNKHD_01778 6.6e-53
IAFDNKHD_01779 3.3e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IAFDNKHD_01780 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_01781 1.2e-123 S Alpha beta hydrolase
IAFDNKHD_01782 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_01783 5.9e-205 L transposase IS116 IS110 IS902 family protein
IAFDNKHD_01784 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01785 8.4e-207 gldA 1.1.1.6 C dehydrogenase
IAFDNKHD_01786 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IAFDNKHD_01787 1.3e-38
IAFDNKHD_01788 4e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
IAFDNKHD_01789 4.6e-36 K Bacterial transcriptional regulator
IAFDNKHD_01791 9e-59 L PFAM transposase IS200-family protein
IAFDNKHD_01792 9.7e-230 L transposase, IS605 OrfB family
IAFDNKHD_01793 1.9e-45 IQ Dehydrogenase reductase
IAFDNKHD_01794 2e-161 S C4-dicarboxylate anaerobic carrier
IAFDNKHD_01795 4e-102 S C4-dicarboxylate anaerobic carrier
IAFDNKHD_01796 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01797 1.4e-243 nhaC C Na H antiporter NhaC
IAFDNKHD_01798 1.6e-241 pbuX F xanthine permease
IAFDNKHD_01799 2.3e-278 pipD E Dipeptidase
IAFDNKHD_01800 2.8e-168 corA P CorA-like Mg2+ transporter protein
IAFDNKHD_01801 3.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IAFDNKHD_01802 6.6e-131 terC P membrane
IAFDNKHD_01803 1.9e-55 trxA O Belongs to the thioredoxin family
IAFDNKHD_01804 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01805 1.3e-221 L COG3547 Transposase and inactivated derivatives
IAFDNKHD_01806 1.7e-240 L Transposase
IAFDNKHD_01807 2.7e-236 mepA V MATE efflux family protein
IAFDNKHD_01808 4.9e-54 K Transcriptional regulator, ArsR family
IAFDNKHD_01809 7.4e-95 P Cadmium resistance transporter
IAFDNKHD_01810 1.1e-43 XK27_08845 S ABC transporter, ATP-binding protein
IAFDNKHD_01811 6.4e-79 XK27_08845 S ABC transporter, ATP-binding protein
IAFDNKHD_01812 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IAFDNKHD_01813 4.1e-181 ABC-SBP S ABC transporter
IAFDNKHD_01814 1.7e-73 M PFAM NLP P60 protein
IAFDNKHD_01815 6e-98 S Protein of unknown function (DUF3278)
IAFDNKHD_01816 1e-28 WQ51_00220 K Helix-turn-helix domain
IAFDNKHD_01817 4.5e-51 L Integrase
IAFDNKHD_01818 1.1e-13 K Transcriptional
IAFDNKHD_01819 3.7e-95 cadD P Cadmium resistance transporter
IAFDNKHD_01820 1.1e-51 cadX K Bacterial regulatory protein, arsR family
IAFDNKHD_01821 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAFDNKHD_01822 6.6e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
IAFDNKHD_01823 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01824 6.4e-08 S HTH domain
IAFDNKHD_01825 7.1e-273 S ABC transporter, ATP-binding protein
IAFDNKHD_01826 5e-142 S Putative ABC-transporter type IV
IAFDNKHD_01827 1.1e-104 NU mannosyl-glycoprotein
IAFDNKHD_01828 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
IAFDNKHD_01829 6.2e-227 S Uncharacterized protein conserved in bacteria (DUF2325)
IAFDNKHD_01830 3.4e-205 nrnB S DHHA1 domain
IAFDNKHD_01831 9.1e-49
IAFDNKHD_01832 5.5e-29 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IAFDNKHD_01833 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_01834 5.3e-16 S Domain of unknown function (DUF4767)
IAFDNKHD_01835 1.5e-52
IAFDNKHD_01836 1.5e-118 yrkL S Flavodoxin-like fold
IAFDNKHD_01838 2.6e-140 L PFAM Integrase catalytic region
IAFDNKHD_01839 5.9e-64 yeaO S Protein of unknown function, DUF488
IAFDNKHD_01840 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IAFDNKHD_01841 2.6e-26 3.1.3.1 S associated with various cellular activities
IAFDNKHD_01842 2.5e-167 3.1.3.1 S associated with various cellular activities
IAFDNKHD_01843 9.6e-231 S Putative metallopeptidase domain
IAFDNKHD_01844 1.9e-46
IAFDNKHD_01845 0.0 pepO 3.4.24.71 O Peptidase family M13
IAFDNKHD_01846 1.4e-105 K Helix-turn-helix XRE-family like proteins
IAFDNKHD_01847 3.9e-87 ymdB S Macro domain protein
IAFDNKHD_01848 3.8e-194 EGP Major facilitator Superfamily
IAFDNKHD_01849 2.3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAFDNKHD_01850 8e-54 K helix_turn_helix, mercury resistance
IAFDNKHD_01851 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IAFDNKHD_01852 5.9e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IAFDNKHD_01853 0.0 ysaB V FtsX-like permease family
IAFDNKHD_01854 4.9e-134 macB2 V ABC transporter, ATP-binding protein
IAFDNKHD_01855 2.8e-182 T PhoQ Sensor
IAFDNKHD_01856 1.9e-124 K response regulator
IAFDNKHD_01857 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
IAFDNKHD_01858 2.9e-134 pnuC H nicotinamide mononucleotide transporter
IAFDNKHD_01859 3.4e-26 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IAFDNKHD_01860 1.9e-38 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IAFDNKHD_01861 5.3e-201
IAFDNKHD_01862 2e-52
IAFDNKHD_01863 9.1e-36
IAFDNKHD_01864 1.5e-91 yxkA S Phosphatidylethanolamine-binding protein
IAFDNKHD_01865 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
IAFDNKHD_01866 4.1e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IAFDNKHD_01867 2.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAFDNKHD_01868 3.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IAFDNKHD_01869 5.4e-181 galR K Transcriptional regulator
IAFDNKHD_01870 7.9e-104 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01871 3.2e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
IAFDNKHD_01872 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IAFDNKHD_01873 1.4e-78 K AsnC family
IAFDNKHD_01874 1.6e-79 uspA T universal stress protein
IAFDNKHD_01875 6.8e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
IAFDNKHD_01876 1.8e-65 ltrA S Bacterial low temperature requirement A protein (LtrA)
IAFDNKHD_01877 1.1e-59 L PFAM transposase IS200-family protein
IAFDNKHD_01878 6.3e-229 L transposase, IS605 OrfB family
IAFDNKHD_01879 0.0 lacS G Transporter
IAFDNKHD_01880 2.3e-28
IAFDNKHD_01881 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAFDNKHD_01882 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAFDNKHD_01883 4.4e-190 yeaN P Transporter, major facilitator family protein
IAFDNKHD_01884 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
IAFDNKHD_01885 2.7e-82 nrdI F Belongs to the NrdI family
IAFDNKHD_01886 1.6e-236 yhdP S Transporter associated domain
IAFDNKHD_01887 1.4e-153 ypdB V (ABC) transporter
IAFDNKHD_01888 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
IAFDNKHD_01889 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
IAFDNKHD_01890 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
IAFDNKHD_01891 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
IAFDNKHD_01892 2.6e-160 S AI-2E family transporter
IAFDNKHD_01893 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IAFDNKHD_01894 2.2e-160
IAFDNKHD_01895 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IAFDNKHD_01896 3.6e-138 eutJ E Hsp70 protein
IAFDNKHD_01897 8.3e-159 K helix_turn_helix, arabinose operon control protein
IAFDNKHD_01898 1.6e-37 pduA_4 CQ BMC
IAFDNKHD_01899 2.7e-134 pduB E BMC
IAFDNKHD_01900 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
IAFDNKHD_01901 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
IAFDNKHD_01902 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
IAFDNKHD_01903 9.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
IAFDNKHD_01904 2.6e-45 pduH S Dehydratase medium subunit
IAFDNKHD_01905 1.8e-56 pduK CQ BMC
IAFDNKHD_01906 7.8e-40 pduA_4 CQ BMC
IAFDNKHD_01907 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
IAFDNKHD_01908 1.3e-79 S Putative propanediol utilisation
IAFDNKHD_01909 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
IAFDNKHD_01910 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
IAFDNKHD_01911 4.5e-77 pduO S Haem-degrading
IAFDNKHD_01912 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
IAFDNKHD_01913 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
IAFDNKHD_01914 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAFDNKHD_01915 1.1e-53 pduU E BMC
IAFDNKHD_01916 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
IAFDNKHD_01917 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
IAFDNKHD_01918 5.9e-68 P Cadmium resistance transporter
IAFDNKHD_01919 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
IAFDNKHD_01920 2.2e-73 fld C Flavodoxin
IAFDNKHD_01921 2.7e-117 XK27_04590 S NADPH-dependent FMN reductase
IAFDNKHD_01922 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
IAFDNKHD_01923 1.8e-169 cobD 4.1.1.81 E Aminotransferase class I and II
IAFDNKHD_01924 8.1e-204 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
IAFDNKHD_01925 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IAFDNKHD_01926 2.5e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
IAFDNKHD_01927 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
IAFDNKHD_01928 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IAFDNKHD_01929 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IAFDNKHD_01930 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IAFDNKHD_01931 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
IAFDNKHD_01932 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IAFDNKHD_01933 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
IAFDNKHD_01934 4.6e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IAFDNKHD_01935 1.8e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
IAFDNKHD_01936 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IAFDNKHD_01937 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IAFDNKHD_01938 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IAFDNKHD_01939 6.8e-103 cbiQ P Cobalt transport protein
IAFDNKHD_01940 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
IAFDNKHD_01941 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
IAFDNKHD_01942 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
IAFDNKHD_01943 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IAFDNKHD_01944 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IAFDNKHD_01945 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
IAFDNKHD_01946 3.9e-240 hemL 5.4.3.8 H Aminotransferase class-III
IAFDNKHD_01947 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
IAFDNKHD_01948 4.9e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IAFDNKHD_01949 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
IAFDNKHD_01950 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IAFDNKHD_01951 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
IAFDNKHD_01952 9.6e-61 L PFAM transposase IS200-family protein
IAFDNKHD_01953 3.7e-229 L transposase, IS605 OrfB family
IAFDNKHD_01954 1.9e-19 cnrT EG PFAM EamA-like transporter family
IAFDNKHD_01955 5.2e-17 cnrT EG PFAM EamA-like transporter family
IAFDNKHD_01956 9.8e-51 S Domain of unknown function (DUF4430)
IAFDNKHD_01957 5.9e-73 S ECF transporter, substrate-specific component
IAFDNKHD_01958 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01959 8.3e-19 S PFAM Archaeal ATPase
IAFDNKHD_01961 1.6e-178 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFDNKHD_01962 1.7e-17 K Winged helix DNA-binding domain
IAFDNKHD_01963 2.9e-299 lmrA V ABC transporter, ATP-binding protein
IAFDNKHD_01964 0.0 yfiC V ABC transporter
IAFDNKHD_01965 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
IAFDNKHD_01966 5.8e-269 pipD E Dipeptidase
IAFDNKHD_01967 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAFDNKHD_01968 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01969 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
IAFDNKHD_01970 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IAFDNKHD_01971 3.6e-236 yagE E amino acid
IAFDNKHD_01972 1.2e-137 aroD S Serine hydrolase (FSH1)
IAFDNKHD_01973 1e-202 brnQ U Component of the transport system for branched-chain amino acids
IAFDNKHD_01974 1.5e-76 L PFAM Integrase catalytic region
IAFDNKHD_01975 5.7e-76 L PFAM Integrase catalytic region
IAFDNKHD_01976 2.9e-165 GK ROK family
IAFDNKHD_01977 0.0 tetP J elongation factor G
IAFDNKHD_01978 5.1e-81 uspA T universal stress protein
IAFDNKHD_01979 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_01980 6.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
IAFDNKHD_01981 7.1e-63
IAFDNKHD_01982 4e-14
IAFDNKHD_01983 5.8e-59
IAFDNKHD_01984 1.8e-38
IAFDNKHD_01985 1.1e-134 V ABC transporter
IAFDNKHD_01986 2.6e-211 EGP Major facilitator Superfamily
IAFDNKHD_01987 7.2e-256 G PTS system Galactitol-specific IIC component
IAFDNKHD_01988 9.8e-23 1.6.5.5 C Zinc-binding dehydrogenase
IAFDNKHD_01989 2e-86 1.6.5.5 C Zinc-binding dehydrogenase
IAFDNKHD_01990 1e-159
IAFDNKHD_01991 1e-72 K Transcriptional regulator
IAFDNKHD_01992 2e-172 D Alpha beta
IAFDNKHD_01993 6.4e-52 ypaA S Protein of unknown function (DUF1304)
IAFDNKHD_01994 0.0 yjcE P Sodium proton antiporter
IAFDNKHD_01995 1.6e-52 yvlA
IAFDNKHD_01996 6.6e-111 P Cobalt transport protein
IAFDNKHD_01997 4.9e-249 cbiO1 S ABC transporter, ATP-binding protein
IAFDNKHD_01998 1.3e-96 S ABC-type cobalt transport system, permease component
IAFDNKHD_01999 9.6e-133 S membrane transporter protein
IAFDNKHD_02000 1.2e-112 IQ KR domain
IAFDNKHD_02001 2e-09 IQ KR domain
IAFDNKHD_02002 1.1e-59 L PFAM transposase IS200-family protein
IAFDNKHD_02003 6.3e-229 L transposase, IS605 OrfB family
IAFDNKHD_02004 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
IAFDNKHD_02005 1.1e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IAFDNKHD_02006 2.3e-28 S Double zinc ribbon
IAFDNKHD_02007 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IAFDNKHD_02008 2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IAFDNKHD_02009 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IAFDNKHD_02010 4.8e-177 yagE E amino acid
IAFDNKHD_02011 9.9e-85 dps P Belongs to the Dps family
IAFDNKHD_02012 0.0 pacL 3.6.3.8 P P-type ATPase
IAFDNKHD_02013 4.4e-140 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IAFDNKHD_02014 5.4e-13 bioH I carboxylic ester hydrolase activity
IAFDNKHD_02015 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IAFDNKHD_02016 1.1e-59 L PFAM transposase IS200-family protein
IAFDNKHD_02017 2.2e-229 L transposase, IS605 OrfB family
IAFDNKHD_02018 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IAFDNKHD_02019 3.9e-145 potB P ABC transporter permease
IAFDNKHD_02020 6.5e-140 potC P ABC transporter permease
IAFDNKHD_02021 1.8e-206 potD P ABC transporter
IAFDNKHD_02022 4.8e-106
IAFDNKHD_02023 9.5e-18
IAFDNKHD_02024 2.3e-31
IAFDNKHD_02025 1.6e-260 S Uncharacterised protein family (UPF0236)
IAFDNKHD_02026 2.1e-60 L PFAM transposase IS200-family protein
IAFDNKHD_02027 2.2e-229 L transposase, IS605 OrfB family
IAFDNKHD_02028 5.7e-231 EGP Sugar (and other) transporter
IAFDNKHD_02029 1e-254 yfnA E Amino Acid
IAFDNKHD_02030 4.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IAFDNKHD_02031 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
IAFDNKHD_02032 9.6e-82 zur P Belongs to the Fur family
IAFDNKHD_02033 4e-17 3.2.1.14 GH18
IAFDNKHD_02034 7.1e-150
IAFDNKHD_02035 1.7e-38 pspC KT positive regulation of macromolecule biosynthetic process
IAFDNKHD_02036 1.7e-93 K Transcriptional regulator (TetR family)
IAFDNKHD_02037 1.7e-219 V domain protein
IAFDNKHD_02038 2.1e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFDNKHD_02040 6.6e-35 S Transglycosylase associated protein
IAFDNKHD_02041 8.6e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAFDNKHD_02042 5e-127 3.1.3.73 G phosphoglycerate mutase
IAFDNKHD_02043 2.8e-114 dedA S SNARE associated Golgi protein
IAFDNKHD_02044 0.0 helD 3.6.4.12 L DNA helicase
IAFDNKHD_02045 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
IAFDNKHD_02046 6.2e-157 EG EamA-like transporter family
IAFDNKHD_02047 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IAFDNKHD_02048 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
IAFDNKHD_02049 1.3e-218 S cog cog1373
IAFDNKHD_02051 4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IAFDNKHD_02056 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_02057 2.1e-31 L Transposase IS66 family
IAFDNKHD_02058 2.8e-197 fhaB M Rib/alpha-like repeat
IAFDNKHD_02064 2.2e-07 S Domain of unknown function (DUF3173)
IAFDNKHD_02065 4.3e-87 L Belongs to the 'phage' integrase family
IAFDNKHD_02066 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_02067 4.6e-16 K Cro/C1-type HTH DNA-binding domain
IAFDNKHD_02068 1.2e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
IAFDNKHD_02069 9.2e-178 L PFAM Integrase catalytic region
IAFDNKHD_02070 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_02071 3.7e-10 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
IAFDNKHD_02072 8.5e-10 L Resolvase, N terminal domain
IAFDNKHD_02073 9.8e-79 L Resolvase, N terminal domain
IAFDNKHD_02074 5.3e-125
IAFDNKHD_02075 0.0
IAFDNKHD_02077 1.4e-33 S Domain of unknown function (DUF3173)
IAFDNKHD_02078 4.9e-229 L Belongs to the 'phage' integrase family
IAFDNKHD_02079 2.9e-224 oxlT P Major Facilitator Superfamily
IAFDNKHD_02080 2.1e-160 spoU 2.1.1.185 J Methyltransferase
IAFDNKHD_02081 3.4e-92 ywlG S Belongs to the UPF0340 family
IAFDNKHD_02082 3.4e-65 L PFAM transposase IS200-family protein
IAFDNKHD_02083 2.8e-229 L transposase, IS605 OrfB family
IAFDNKHD_02084 1.5e-42 wecD3 K PFAM GCN5-related N-acetyltransferase
IAFDNKHD_02085 3.3e-37 ltrA S Bacterial low temperature requirement A protein (LtrA)
IAFDNKHD_02086 1.5e-40 ltrA S Bacterial low temperature requirement A protein (LtrA)
IAFDNKHD_02087 8.6e-50 L Transposase IS200 like
IAFDNKHD_02088 5.5e-185 L transposase, IS605 OrfB family
IAFDNKHD_02089 8.2e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
IAFDNKHD_02090 4.3e-13
IAFDNKHD_02091 3.2e-74 L PFAM Integrase catalytic region
IAFDNKHD_02092 9.5e-39 S Cytochrome B5
IAFDNKHD_02093 1.3e-16 L Transposase
IAFDNKHD_02094 1e-36 L Helix-turn-helix domain
IAFDNKHD_02095 3.9e-122 O Zinc-dependent metalloprotease
IAFDNKHD_02096 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IAFDNKHD_02097 1.1e-158 metQ_4 P Belongs to the nlpA lipoprotein family
IAFDNKHD_02098 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_02101 1.7e-183 S Phosphotransferase system, EIIC
IAFDNKHD_02102 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAFDNKHD_02103 1.1e-200 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_02104 3.9e-182
IAFDNKHD_02105 1.8e-264 L PFAM Integrase catalytic region
IAFDNKHD_02106 4.7e-63 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAFDNKHD_02107 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
IAFDNKHD_02108 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
IAFDNKHD_02109 1.2e-97 2.3.1.128 K acetyltransferase
IAFDNKHD_02110 3.9e-187
IAFDNKHD_02111 1.4e-12 K Transcriptional regulator, HxlR family
IAFDNKHD_02112 3.7e-40 L Transposase
IAFDNKHD_02113 2.4e-36 L Transposase
IAFDNKHD_02114 9.5e-80 L Transposase
IAFDNKHD_02115 1.6e-88 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
IAFDNKHD_02116 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_02117 1e-119 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_02118 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_02119 5.1e-133 K Transcriptional regulatory protein, C-terminal domain protein
IAFDNKHD_02120 4.6e-160 pstS P Phosphate
IAFDNKHD_02121 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
IAFDNKHD_02122 2.6e-155 pstA P Phosphate transport system permease protein PstA
IAFDNKHD_02123 4e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IAFDNKHD_02124 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
IAFDNKHD_02125 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_02126 1.2e-139
IAFDNKHD_02128 1.2e-241 ydaM M Glycosyl transferase
IAFDNKHD_02129 1.4e-222 G Glycosyl hydrolases family 8
IAFDNKHD_02130 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IAFDNKHD_02131 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_02132 1.9e-236 L transposase IS116 IS110 IS902 family protein
IAFDNKHD_02133 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IAFDNKHD_02134 7.6e-239 ktrB P Potassium uptake protein
IAFDNKHD_02135 7.7e-115 ktrA P domain protein
IAFDNKHD_02136 2.4e-79 Q Methyltransferase
IAFDNKHD_02137 2e-231 mntH P H( )-stimulated, divalent metal cation uptake system
IAFDNKHD_02138 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IAFDNKHD_02139 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IAFDNKHD_02140 8.4e-85 S NADPH-dependent FMN reductase
IAFDNKHD_02141 4e-179 MA20_14895 S Conserved hypothetical protein 698
IAFDNKHD_02142 3e-133 I alpha/beta hydrolase fold
IAFDNKHD_02143 3.8e-114 lsa S ABC transporter
IAFDNKHD_02144 2.6e-91 lsa S ABC transporter
IAFDNKHD_02145 1.1e-180 yfeX P Peroxidase
IAFDNKHD_02146 4.4e-122 arcD S C4-dicarboxylate anaerobic carrier
IAFDNKHD_02147 1.5e-140 L PFAM Integrase catalytic region
IAFDNKHD_02148 2.7e-241 L Transposase
IAFDNKHD_02149 2.4e-16 arcD S C4-dicarboxylate anaerobic carrier
IAFDNKHD_02150 1.1e-124 arcD S C4-dicarboxylate anaerobic carrier
IAFDNKHD_02151 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
IAFDNKHD_02152 1.3e-216 uhpT EGP Major facilitator Superfamily
IAFDNKHD_02153 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
IAFDNKHD_02154 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_02155 5.3e-131 ponA V Beta-lactamase enzyme family
IAFDNKHD_02156 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IAFDNKHD_02157 3.7e-73
IAFDNKHD_02158 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_02159 2.3e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IAFDNKHD_02160 2.2e-21
IAFDNKHD_02161 1.2e-216 S Uncharacterized protein conserved in bacteria (DUF2252)
IAFDNKHD_02162 3.5e-23 S Uncharacterized protein conserved in bacteria (DUF2252)
IAFDNKHD_02163 1.1e-169 L transposase, IS605 OrfB family
IAFDNKHD_02165 7.8e-32 L PFAM plasmid pRiA4b ORF-3 family protein
IAFDNKHD_02166 7.7e-227 L PFAM plasmid pRiA4b ORF-3 family protein
IAFDNKHD_02167 9.6e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
IAFDNKHD_02168 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAFDNKHD_02169 4.3e-158 mleR K LysR family
IAFDNKHD_02170 8.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IAFDNKHD_02171 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IAFDNKHD_02172 4.5e-266 frdC 1.3.5.4 C FAD binding domain
IAFDNKHD_02173 3.5e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IAFDNKHD_02174 9.3e-203 P Sodium:sulfate symporter transmembrane region
IAFDNKHD_02175 1.4e-125 citR K sugar-binding domain protein
IAFDNKHD_02176 6.1e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IAFDNKHD_02177 1.7e-148 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IAFDNKHD_02178 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
IAFDNKHD_02179 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IAFDNKHD_02180 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IAFDNKHD_02181 3.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IAFDNKHD_02182 3.8e-113 ydjP I Alpha/beta hydrolase family
IAFDNKHD_02183 1.1e-158 mleR K LysR family
IAFDNKHD_02184 9.4e-253 yjjP S Putative threonine/serine exporter
IAFDNKHD_02185 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
IAFDNKHD_02186 6.5e-271 emrY EGP Major facilitator Superfamily
IAFDNKHD_02187 2.7e-185 I Alpha beta
IAFDNKHD_02188 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IAFDNKHD_02189 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAFDNKHD_02190 2.6e-93 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAFDNKHD_02191 1.4e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_02193 1.1e-200 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_02194 4.4e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IAFDNKHD_02195 4e-141 L PFAM Integrase catalytic region
IAFDNKHD_02196 2.9e-123 S Domain of unknown function (DUF4811)
IAFDNKHD_02197 3.6e-269 lmrB EGP Major facilitator Superfamily
IAFDNKHD_02198 9.8e-74 merR K MerR HTH family regulatory protein
IAFDNKHD_02199 7.9e-55
IAFDNKHD_02200 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAFDNKHD_02201 8.3e-221 S CAAX protease self-immunity
IAFDNKHD_02202 3.6e-109 glnP P ABC transporter permease
IAFDNKHD_02203 2.4e-110 gluC P ABC transporter permease
IAFDNKHD_02204 2.8e-151 glnH ET ABC transporter
IAFDNKHD_02205 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAFDNKHD_02206 5.5e-83 usp1 T Belongs to the universal stress protein A family
IAFDNKHD_02207 7.7e-107 S VIT family
IAFDNKHD_02208 2.5e-116 S membrane
IAFDNKHD_02209 5.5e-164 czcD P cation diffusion facilitator family transporter
IAFDNKHD_02210 1.6e-123 sirR K iron dependent repressor
IAFDNKHD_02211 1e-30 cspC K Cold shock protein
IAFDNKHD_02212 2e-127 thrE S Putative threonine/serine exporter
IAFDNKHD_02213 1.4e-81 S Threonine/Serine exporter, ThrE
IAFDNKHD_02214 9.8e-118 lssY 3.6.1.27 I phosphatase
IAFDNKHD_02215 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
IAFDNKHD_02216 1.5e-275 lysP E amino acid
IAFDNKHD_02217 9e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IAFDNKHD_02223 5.3e-176 L PFAM Integrase catalytic region
IAFDNKHD_02224 3.9e-34 L PFAM Integrase catalytic region
IAFDNKHD_02225 1.2e-81 L PFAM Integrase catalytic region
IAFDNKHD_02226 1.8e-200 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IAFDNKHD_02227 1.3e-154 S Hydrolases of the alpha beta superfamily
IAFDNKHD_02228 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
IAFDNKHD_02229 4.4e-77 ctsR K Belongs to the CtsR family
IAFDNKHD_02230 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IAFDNKHD_02231 1e-110 K Bacterial regulatory proteins, tetR family
IAFDNKHD_02232 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAFDNKHD_02233 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAFDNKHD_02234 2.3e-199 ykiI
IAFDNKHD_02235 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
IAFDNKHD_02236 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAFDNKHD_02237 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IAFDNKHD_02238 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAFDNKHD_02239 4.8e-65 L Transposase
IAFDNKHD_02240 9.7e-123 L Transposase
IAFDNKHD_02241 2.6e-74 L transposase IS116 IS110 IS902 family protein
IAFDNKHD_02242 2.2e-50
IAFDNKHD_02244 3.5e-12
IAFDNKHD_02246 0.0 copB 3.6.3.4 P P-type ATPase
IAFDNKHD_02247 6.5e-75 K Copper transport repressor CopY TcrY
IAFDNKHD_02248 1.9e-56 cadX K Bacterial regulatory protein, arsR family
IAFDNKHD_02249 1.1e-67 cadD P Cadmium resistance transporter
IAFDNKHD_02252 2.5e-93 L Integrase
IAFDNKHD_02254 1e-262 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IAFDNKHD_02257 1.8e-87 tra L Transposase and inactivated derivatives, IS30 family
IAFDNKHD_02259 5.2e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
IAFDNKHD_02260 8.3e-34
IAFDNKHD_02261 3.6e-07 L Resolvase, N terminal domain
IAFDNKHD_02262 1.9e-185 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
IAFDNKHD_02263 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)