ORF_ID e_value Gene_name EC_number CAZy COGs Description
IOLLKAAL_00001 9.1e-34 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOLLKAAL_00002 2.4e-99 M Transport protein ComB
IOLLKAAL_00004 1.3e-45 S Enterocin A Immunity
IOLLKAAL_00005 9.1e-223 S CAAX protease self-immunity
IOLLKAAL_00009 1.8e-53 S Enterocin A Immunity
IOLLKAAL_00011 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
IOLLKAAL_00012 3.6e-162 rssA S Phospholipase, patatin family
IOLLKAAL_00013 1.5e-256 glnPH2 P ABC transporter permease
IOLLKAAL_00014 3.2e-130 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOLLKAAL_00015 2.8e-96 K Acetyltransferase (GNAT) domain
IOLLKAAL_00016 7.8e-160 pstS P Phosphate
IOLLKAAL_00017 1.2e-161 pstC P probably responsible for the translocation of the substrate across the membrane
IOLLKAAL_00018 3.7e-157 pstA P Phosphate transport system permease protein PstA
IOLLKAAL_00019 6.3e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOLLKAAL_00020 3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOLLKAAL_00021 1.9e-108 phoU P Plays a role in the regulation of phosphate uptake
IOLLKAAL_00022 4.6e-280 S C4-dicarboxylate anaerobic carrier
IOLLKAAL_00023 2.6e-85 dps P Belongs to the Dps family
IOLLKAAL_00024 2.7e-158 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOLLKAAL_00025 3.1e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOLLKAAL_00026 8.2e-176 rihB 3.2.2.1 F Nucleoside
IOLLKAAL_00027 8.9e-133 gntR K UbiC transcription regulator-associated domain protein
IOLLKAAL_00028 3.5e-52 S Enterocin A Immunity
IOLLKAAL_00029 4.7e-140 glcR K DeoR C terminal sensor domain
IOLLKAAL_00030 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IOLLKAAL_00031 1.3e-119 C nitroreductase
IOLLKAAL_00032 3e-130
IOLLKAAL_00033 1.1e-237 yhdP S Transporter associated domain
IOLLKAAL_00034 9.8e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOLLKAAL_00035 8e-233 potE E amino acid
IOLLKAAL_00036 7.6e-137 M Glycosyl hydrolases family 25
IOLLKAAL_00037 2.7e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
IOLLKAAL_00038 2.3e-251 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOLLKAAL_00041 5.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOLLKAAL_00042 3.6e-88 gtcA S Teichoic acid glycosylation protein
IOLLKAAL_00043 2.5e-77 fld C Flavodoxin
IOLLKAAL_00044 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
IOLLKAAL_00045 1.1e-161 yihY S Belongs to the UPF0761 family
IOLLKAAL_00046 1.2e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOLLKAAL_00047 1.8e-181 E ABC transporter, ATP-binding protein
IOLLKAAL_00048 9.6e-286 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOLLKAAL_00049 2.5e-68 O OsmC-like protein
IOLLKAAL_00050 2.8e-163 ltrA S Bacterial low temperature requirement A protein (LtrA)
IOLLKAAL_00051 3.5e-114 2.7.6.5 T Region found in RelA / SpoT proteins
IOLLKAAL_00052 5.3e-116 K response regulator
IOLLKAAL_00053 1.7e-227 sptS 2.7.13.3 T Histidine kinase
IOLLKAAL_00054 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IOLLKAAL_00055 0.0 pepN 3.4.11.2 E aminopeptidase
IOLLKAAL_00056 2.8e-145 S haloacid dehalogenase-like hydrolase
IOLLKAAL_00058 2e-294 V ABC transporter transmembrane region
IOLLKAAL_00059 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOLLKAAL_00060 1.1e-69
IOLLKAAL_00061 3.2e-107 fic D Fic/DOC family
IOLLKAAL_00062 2.5e-141 ppm1 GT2 M Glycosyl transferase family 2
IOLLKAAL_00063 5.1e-96 S Domain of unknown function (DUF4811)
IOLLKAAL_00064 4.7e-266 lmrB EGP Major facilitator Superfamily
IOLLKAAL_00065 1.9e-77 K MerR HTH family regulatory protein
IOLLKAAL_00066 0.0 oppA E ABC transporter substrate-binding protein
IOLLKAAL_00067 4.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
IOLLKAAL_00068 7.9e-257 pepC 3.4.22.40 E Peptidase C1-like family
IOLLKAAL_00071 1.2e-80 3.4.22.70 M Sortase family
IOLLKAAL_00072 7.8e-10 2.7.1.2 GK ROK family
IOLLKAAL_00073 3.1e-133 2.7.1.2 GK ROK family
IOLLKAAL_00074 1.9e-61 K AraC-like ligand binding domain
IOLLKAAL_00075 3.5e-43 rhaS6 K helix_turn_helix, arabinose operon control protein
IOLLKAAL_00076 1.2e-176 I Carboxylesterase family
IOLLKAAL_00077 2.5e-311 S Predicted membrane protein (DUF2207)
IOLLKAAL_00078 4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IOLLKAAL_00079 9.7e-85
IOLLKAAL_00080 5e-148 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IOLLKAAL_00081 9e-93 S ECF-type riboflavin transporter, S component
IOLLKAAL_00082 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IOLLKAAL_00083 6.3e-64
IOLLKAAL_00084 3.5e-12
IOLLKAAL_00085 1.5e-215 S Uncharacterized protein conserved in bacteria (DUF2325)
IOLLKAAL_00086 2.9e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOLLKAAL_00087 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
IOLLKAAL_00088 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IOLLKAAL_00089 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IOLLKAAL_00090 6.4e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOLLKAAL_00091 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOLLKAAL_00092 8.2e-73 yqhY S Asp23 family, cell envelope-related function
IOLLKAAL_00093 3.6e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOLLKAAL_00094 3.9e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOLLKAAL_00095 7.2e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOLLKAAL_00096 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOLLKAAL_00097 1.5e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOLLKAAL_00098 4.6e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IOLLKAAL_00099 8.5e-296 recN L May be involved in recombinational repair of damaged DNA
IOLLKAAL_00100 1e-47
IOLLKAAL_00101 7.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
IOLLKAAL_00102 2.3e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOLLKAAL_00103 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOLLKAAL_00104 7.4e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOLLKAAL_00105 7.5e-239 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOLLKAAL_00106 4.5e-140 stp 3.1.3.16 T phosphatase
IOLLKAAL_00107 0.0 KLT serine threonine protein kinase
IOLLKAAL_00108 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOLLKAAL_00109 2e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IOLLKAAL_00110 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
IOLLKAAL_00111 1.2e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IOLLKAAL_00112 1.4e-57 asp S Asp23 family, cell envelope-related function
IOLLKAAL_00113 3.6e-307 yloV S DAK2 domain fusion protein YloV
IOLLKAAL_00114 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOLLKAAL_00115 6e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOLLKAAL_00116 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOLLKAAL_00117 9e-192 oppD P Belongs to the ABC transporter superfamily
IOLLKAAL_00118 9.9e-180 oppF P Belongs to the ABC transporter superfamily
IOLLKAAL_00119 5.6e-175 oppB P ABC transporter permease
IOLLKAAL_00120 1.1e-161 oppC P Binding-protein-dependent transport system inner membrane component
IOLLKAAL_00121 0.0 oppA E ABC transporter substrate-binding protein
IOLLKAAL_00122 0.0 oppA E ABC transporter substrate-binding protein
IOLLKAAL_00123 2.7e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOLLKAAL_00124 0.0 smc D Required for chromosome condensation and partitioning
IOLLKAAL_00125 2.6e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOLLKAAL_00126 3.6e-287 pipD E Dipeptidase
IOLLKAAL_00127 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOLLKAAL_00128 3.8e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOLLKAAL_00129 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IOLLKAAL_00130 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOLLKAAL_00131 5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IOLLKAAL_00132 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOLLKAAL_00133 2.1e-117 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOLLKAAL_00134 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IOLLKAAL_00135 2.1e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
IOLLKAAL_00136 1e-113 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOLLKAAL_00137 2.5e-34 ynzC S UPF0291 protein
IOLLKAAL_00138 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
IOLLKAAL_00139 0.0 mdlA V ABC transporter
IOLLKAAL_00140 1.4e-283 mdlB V ABC transporter
IOLLKAAL_00141 3e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IOLLKAAL_00142 2.6e-117 plsC 2.3.1.51 I Acyltransferase
IOLLKAAL_00143 1.8e-195 yabB 2.1.1.223 L Methyltransferase small domain
IOLLKAAL_00144 5.8e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
IOLLKAAL_00145 9.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOLLKAAL_00146 1.8e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IOLLKAAL_00147 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOLLKAAL_00148 1.2e-134 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOLLKAAL_00149 1.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IOLLKAAL_00150 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IOLLKAAL_00151 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOLLKAAL_00152 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOLLKAAL_00153 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
IOLLKAAL_00154 3.2e-220 nusA K Participates in both transcription termination and antitermination
IOLLKAAL_00155 1.5e-46 ylxR K Protein of unknown function (DUF448)
IOLLKAAL_00156 7.1e-47 rplGA J ribosomal protein
IOLLKAAL_00157 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOLLKAAL_00158 3.5e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOLLKAAL_00159 2.3e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOLLKAAL_00160 1.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IOLLKAAL_00161 1.6e-282 lsa S ABC transporter
IOLLKAAL_00162 9.8e-96 S GyrI-like small molecule binding domain
IOLLKAAL_00163 1.7e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOLLKAAL_00164 5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOLLKAAL_00165 0.0 dnaK O Heat shock 70 kDa protein
IOLLKAAL_00166 5.7e-174 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOLLKAAL_00167 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOLLKAAL_00168 3.5e-123 srtA 3.4.22.70 M sortase family
IOLLKAAL_00169 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IOLLKAAL_00170 4.8e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOLLKAAL_00171 1.8e-276 yjeM E Amino Acid
IOLLKAAL_00172 2e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOLLKAAL_00173 1.1e-186 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOLLKAAL_00174 9e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOLLKAAL_00175 1.7e-251 G Major Facilitator
IOLLKAAL_00176 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
IOLLKAAL_00177 1.9e-158 lysR5 K LysR substrate binding domain
IOLLKAAL_00179 1.3e-102 3.6.1.27 I Acid phosphatase homologues
IOLLKAAL_00180 6.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOLLKAAL_00181 3.7e-18 S Sugar efflux transporter for intercellular exchange
IOLLKAAL_00182 5.7e-305 ybiT S ABC transporter, ATP-binding protein
IOLLKAAL_00183 7.4e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOLLKAAL_00184 8.6e-48 K Helix-turn-helix domain
IOLLKAAL_00185 2.6e-139 F DNA/RNA non-specific endonuclease
IOLLKAAL_00186 3.2e-55 L nuclease
IOLLKAAL_00187 4.6e-157 metQ1 P Belongs to the nlpA lipoprotein family
IOLLKAAL_00188 2.6e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOLLKAAL_00189 9.6e-68 metI P ABC transporter permease
IOLLKAAL_00190 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOLLKAAL_00191 2.3e-262 frdC 1.3.5.4 C FAD binding domain
IOLLKAAL_00192 6.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOLLKAAL_00193 4.9e-241 yjjP S Putative threonine/serine exporter
IOLLKAAL_00194 5e-190 ansA 3.5.1.1 EJ L-asparaginase, type I
IOLLKAAL_00195 0.0 aha1 P E1-E2 ATPase
IOLLKAAL_00196 3.5e-310 S Bacterial membrane protein, YfhO
IOLLKAAL_00197 5.3e-68 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOLLKAAL_00198 9.7e-172 prmA J Ribosomal protein L11 methyltransferase
IOLLKAAL_00199 2.4e-65
IOLLKAAL_00200 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOLLKAAL_00201 1.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOLLKAAL_00202 6.2e-246 hisS 6.1.1.21 J histidyl-tRNA synthetase
IOLLKAAL_00203 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IOLLKAAL_00204 1.8e-223 patA 2.6.1.1 E Aminotransferase
IOLLKAAL_00205 3.1e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IOLLKAAL_00206 3.4e-135 E GDSL-like Lipase/Acylhydrolase family
IOLLKAAL_00207 1.6e-07
IOLLKAAL_00208 1.8e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOLLKAAL_00209 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOLLKAAL_00210 8.7e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IOLLKAAL_00211 8.8e-151 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IOLLKAAL_00212 1.1e-50 S Iron-sulfur cluster assembly protein
IOLLKAAL_00213 1.7e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOLLKAAL_00214 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IOLLKAAL_00215 2.9e-33 yqeY S YqeY-like protein
IOLLKAAL_00216 6.8e-173 phoH T phosphate starvation-inducible protein PhoH
IOLLKAAL_00217 2.6e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOLLKAAL_00218 7.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOLLKAAL_00219 1.4e-136 recO L Involved in DNA repair and RecF pathway recombination
IOLLKAAL_00220 2.7e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IOLLKAAL_00221 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IOLLKAAL_00222 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOLLKAAL_00223 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOLLKAAL_00224 4.7e-120
IOLLKAAL_00225 5.4e-92
IOLLKAAL_00227 3.1e-185 M domain protein
IOLLKAAL_00228 5.1e-164 S DNA/RNA non-specific endonuclease
IOLLKAAL_00229 2.8e-129 ybbM S Uncharacterised protein family (UPF0014)
IOLLKAAL_00230 4.4e-115 ybbL S ABC transporter, ATP-binding protein
IOLLKAAL_00232 3.3e-208 pepA E M42 glutamyl aminopeptidase
IOLLKAAL_00233 6.5e-78
IOLLKAAL_00234 6.7e-69 K helix_turn_helix multiple antibiotic resistance protein
IOLLKAAL_00235 8.6e-28
IOLLKAAL_00236 6.5e-213 mdtG EGP Major facilitator Superfamily
IOLLKAAL_00237 1.2e-244 yagE E amino acid
IOLLKAAL_00238 1.8e-286 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
IOLLKAAL_00239 9.5e-155 E Amino acid permease
IOLLKAAL_00240 1.3e-309 gadC E Contains amino acid permease domain
IOLLKAAL_00241 1.6e-265 pepC 3.4.22.40 E Peptidase C1-like family
IOLLKAAL_00242 6.3e-276 pipD E Peptidase family C69
IOLLKAAL_00243 5.8e-281 gadC E Contains amino acid permease domain
IOLLKAAL_00244 8e-265 pepC 3.4.22.40 E Peptidase C1-like family
IOLLKAAL_00245 3.9e-283 E Phospholipase B
IOLLKAAL_00246 2.8e-111 3.6.1.27 I Acid phosphatase homologues
IOLLKAAL_00247 8.8e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
IOLLKAAL_00248 4e-278 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IOLLKAAL_00249 1.1e-298 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
IOLLKAAL_00250 1.5e-53 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
IOLLKAAL_00251 3.4e-96 lacT K CAT RNA binding domain
IOLLKAAL_00252 2.5e-14 lacT K CAT RNA binding domain
IOLLKAAL_00253 1.6e-105 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
IOLLKAAL_00254 5.1e-72 lacA 5.3.1.26 G Ribose/Galactose Isomerase
IOLLKAAL_00255 6e-132 lacR K DeoR C terminal sensor domain
IOLLKAAL_00256 4.3e-242 pyrP F Permease
IOLLKAAL_00257 7.7e-157 K Transcriptional regulator
IOLLKAAL_00258 4.4e-149 S hydrolase
IOLLKAAL_00259 5.1e-101 yagU S Protein of unknown function (DUF1440)
IOLLKAAL_00260 7.6e-146 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IOLLKAAL_00261 7.9e-202 S PFAM Archaeal ATPase
IOLLKAAL_00262 3.5e-82 2.3.1.128 K acetyltransferase
IOLLKAAL_00263 4e-16
IOLLKAAL_00265 3.1e-69
IOLLKAAL_00266 3.6e-258 emrY EGP Major facilitator Superfamily
IOLLKAAL_00267 4.6e-253 emrY EGP Major facilitator Superfamily
IOLLKAAL_00268 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOLLKAAL_00269 9.3e-136 S CAAX amino terminal protease
IOLLKAAL_00270 1.5e-161 mleP3 S Membrane transport protein
IOLLKAAL_00271 8.5e-99 tag 3.2.2.20 L glycosylase
IOLLKAAL_00272 2.1e-193 S Bacteriocin helveticin-J
IOLLKAAL_00273 1.9e-220 yfeO P Voltage gated chloride channel
IOLLKAAL_00274 8.5e-81 yebR 1.8.4.14 T GAF domain-containing protein
IOLLKAAL_00275 1.4e-110 ylbE GM NAD(P)H-binding
IOLLKAAL_00276 1.5e-126 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
IOLLKAAL_00277 1.5e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOLLKAAL_00279 2.8e-134 K Sigma-54 factor, core binding domain
IOLLKAAL_00280 2.6e-113 mgtC S MgtC family
IOLLKAAL_00281 4.5e-149 ptsD G PTS system mannose/fructose/sorbose family IID component
IOLLKAAL_00282 3.1e-137 ptsC G PTS system sorbose-specific iic component
IOLLKAAL_00283 7e-81 ptsB 2.7.1.191 G PTS system sorbose subfamily IIB component
IOLLKAAL_00284 3.2e-55 2.7.1.191 G PTS system fructose IIA component
IOLLKAAL_00285 0.0 K Sigma-54 interaction domain
IOLLKAAL_00286 5.1e-45
IOLLKAAL_00287 1.9e-172 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IOLLKAAL_00288 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IOLLKAAL_00289 4e-170 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IOLLKAAL_00290 8.7e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOLLKAAL_00291 4e-136
IOLLKAAL_00292 1.5e-216 MA20_36090 S Protein of unknown function (DUF2974)
IOLLKAAL_00293 1.2e-299 ytgP S Polysaccharide biosynthesis protein
IOLLKAAL_00294 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOLLKAAL_00295 2.3e-116 3.6.1.27 I Acid phosphatase homologues
IOLLKAAL_00296 1.1e-251 yfnA E Amino Acid
IOLLKAAL_00297 0.0 clpE2 O AAA domain (Cdc48 subfamily)
IOLLKAAL_00298 5.5e-172 S Alpha/beta hydrolase of unknown function (DUF915)
IOLLKAAL_00299 1.6e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOLLKAAL_00300 5.4e-39
IOLLKAAL_00301 2.8e-216 lmrP E Major Facilitator Superfamily
IOLLKAAL_00302 1.2e-146 pbpX2 V Beta-lactamase
IOLLKAAL_00303 9e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOLLKAAL_00304 6.7e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOLLKAAL_00305 6.1e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
IOLLKAAL_00306 1.9e-291 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOLLKAAL_00308 3.9e-39
IOLLKAAL_00309 8.9e-204 ywhK S Membrane
IOLLKAAL_00311 5.7e-59
IOLLKAAL_00312 1.1e-49
IOLLKAAL_00313 2.1e-45
IOLLKAAL_00314 2.7e-85 ykuL S (CBS) domain
IOLLKAAL_00315 0.0 cadA P P-type ATPase
IOLLKAAL_00316 4.9e-202 napA P Sodium/hydrogen exchanger family
IOLLKAAL_00317 1e-95 S Putative adhesin
IOLLKAAL_00318 9.1e-284 V ABC transporter transmembrane region
IOLLKAAL_00319 1.6e-160 mutR K Helix-turn-helix XRE-family like proteins
IOLLKAAL_00320 3.5e-35
IOLLKAAL_00321 1.7e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOLLKAAL_00322 3.5e-158 S Protein of unknown function (DUF979)
IOLLKAAL_00323 6.6e-114 S Protein of unknown function (DUF969)
IOLLKAAL_00324 4.9e-87 S Protein of unknown function (DUF805)
IOLLKAAL_00325 4.4e-07
IOLLKAAL_00326 4.1e-15
IOLLKAAL_00327 8.5e-268 G PTS system Galactitol-specific IIC component
IOLLKAAL_00328 6.1e-96 S Protein of unknown function (DUF1440)
IOLLKAAL_00329 1.8e-105 S CAAX protease self-immunity
IOLLKAAL_00330 1e-204 S DUF218 domain
IOLLKAAL_00331 0.0 macB_3 V ABC transporter, ATP-binding protein
IOLLKAAL_00332 6.2e-268 cydA 1.10.3.14 C ubiquinol oxidase
IOLLKAAL_00333 2.4e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IOLLKAAL_00334 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IOLLKAAL_00335 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IOLLKAAL_00336 1.2e-177 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IOLLKAAL_00337 8.3e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
IOLLKAAL_00338 1.9e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
IOLLKAAL_00339 1.9e-150 K Helix-turn-helix domain, rpiR family
IOLLKAAL_00340 6.6e-169 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
IOLLKAAL_00341 4.4e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOLLKAAL_00342 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOLLKAAL_00343 1.9e-130 S membrane transporter protein
IOLLKAAL_00344 6.2e-162 yeaE S Aldo/keto reductase family
IOLLKAAL_00345 2.3e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOLLKAAL_00346 1e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IOLLKAAL_00347 6.3e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IOLLKAAL_00348 3.3e-236 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IOLLKAAL_00349 3e-232 pbuG S permease
IOLLKAAL_00350 7.9e-129 K helix_turn_helix, mercury resistance
IOLLKAAL_00351 5.7e-231 pbuG S permease
IOLLKAAL_00352 4.2e-226 pbuG S permease
IOLLKAAL_00353 3.9e-76 K Bacteriophage CI repressor helix-turn-helix domain
IOLLKAAL_00354 1.5e-68 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IOLLKAAL_00355 2.3e-72
IOLLKAAL_00356 1.4e-90
IOLLKAAL_00357 4.3e-74 atkY K Penicillinase repressor
IOLLKAAL_00358 2.7e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOLLKAAL_00359 2.2e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOLLKAAL_00360 0.0 copA 3.6.3.54 P P-type ATPase
IOLLKAAL_00361 6.6e-107 3.2.2.20 K acetyltransferase
IOLLKAAL_00362 8.7e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOLLKAAL_00363 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOLLKAAL_00364 5.5e-28 secG U Preprotein translocase
IOLLKAAL_00365 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOLLKAAL_00366 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOLLKAAL_00367 3.5e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IOLLKAAL_00368 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOLLKAAL_00369 1.4e-187 cggR K Putative sugar-binding domain
IOLLKAAL_00371 2.4e-278 ycaM E amino acid
IOLLKAAL_00372 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOLLKAAL_00373 6.2e-171 whiA K May be required for sporulation
IOLLKAAL_00374 5.8e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IOLLKAAL_00375 1.6e-160 rapZ S Displays ATPase and GTPase activities
IOLLKAAL_00376 8.1e-91 S Short repeat of unknown function (DUF308)
IOLLKAAL_00377 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOLLKAAL_00378 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOLLKAAL_00379 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IOLLKAAL_00380 4.7e-161 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IOLLKAAL_00381 1.1e-254 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IOLLKAAL_00382 3.9e-207 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOLLKAAL_00383 0.0 lacZ 3.2.1.23 G -beta-galactosidase
IOLLKAAL_00384 0.0 lacS G Transporter
IOLLKAAL_00385 3.5e-188 lacR K Transcriptional regulator
IOLLKAAL_00386 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IOLLKAAL_00387 2e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IOLLKAAL_00388 1.8e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOLLKAAL_00389 9e-18 rnhA 3.1.26.4 L Ribonuclease HI
IOLLKAAL_00391 6.1e-39 D nuclear chromosome segregation
IOLLKAAL_00392 7.1e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOLLKAAL_00393 3.3e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IOLLKAAL_00394 1.2e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOLLKAAL_00395 4.7e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOLLKAAL_00396 7.6e-24
IOLLKAAL_00397 3.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOLLKAAL_00398 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOLLKAAL_00399 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOLLKAAL_00400 9.7e-126 comFC S Competence protein
IOLLKAAL_00401 1.5e-225 comFA L Helicase C-terminal domain protein
IOLLKAAL_00402 4.3e-118 yvyE 3.4.13.9 S YigZ family
IOLLKAAL_00403 1.6e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
IOLLKAAL_00404 6.9e-194 rny S Endoribonuclease that initiates mRNA decay
IOLLKAAL_00405 3.5e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOLLKAAL_00406 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOLLKAAL_00407 9.8e-125 ymfM S Helix-turn-helix domain
IOLLKAAL_00408 3.7e-131 IQ Enoyl-(Acyl carrier protein) reductase
IOLLKAAL_00409 1.3e-229 S Peptidase M16
IOLLKAAL_00410 2.5e-228 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
IOLLKAAL_00411 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IOLLKAAL_00412 1.7e-75 WQ51_03320 S Protein of unknown function (DUF1149)
IOLLKAAL_00413 4.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOLLKAAL_00414 7.2e-209 yubA S AI-2E family transporter
IOLLKAAL_00415 4.9e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IOLLKAAL_00416 2.2e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IOLLKAAL_00417 4.2e-62 yugI 5.3.1.9 J general stress protein
IOLLKAAL_00418 1.4e-178 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IOLLKAAL_00419 2.7e-117 dedA S SNARE-like domain protein
IOLLKAAL_00420 1.5e-104 S Protein of unknown function (DUF1461)
IOLLKAAL_00421 1.2e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOLLKAAL_00422 9.3e-95 yutD S Protein of unknown function (DUF1027)
IOLLKAAL_00423 1e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IOLLKAAL_00424 1.3e-54
IOLLKAAL_00425 6.8e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOLLKAAL_00426 9e-275 pepV 3.5.1.18 E dipeptidase PepV
IOLLKAAL_00427 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
IOLLKAAL_00428 9.8e-175 ccpA K catabolite control protein A
IOLLKAAL_00429 3.8e-212 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOLLKAAL_00430 9.6e-50
IOLLKAAL_00431 1.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOLLKAAL_00432 6e-139 ykuT M mechanosensitive ion channel
IOLLKAAL_00433 2.9e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOLLKAAL_00434 0.0 UW LPXTG-motif cell wall anchor domain protein
IOLLKAAL_00435 1.5e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOLLKAAL_00436 1.7e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOLLKAAL_00437 3.2e-68 yslB S Protein of unknown function (DUF2507)
IOLLKAAL_00438 1.1e-52 trxA O Belongs to the thioredoxin family
IOLLKAAL_00439 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOLLKAAL_00440 3.9e-93 cvpA S Colicin V production protein
IOLLKAAL_00441 4.2e-39 yrzB S Belongs to the UPF0473 family
IOLLKAAL_00442 8.8e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOLLKAAL_00443 2.6e-42 yrzL S Belongs to the UPF0297 family
IOLLKAAL_00444 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOLLKAAL_00445 1.8e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOLLKAAL_00446 1.9e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IOLLKAAL_00447 1.2e-208 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOLLKAAL_00448 1.1e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOLLKAAL_00449 1.2e-39 yajC U Preprotein translocase
IOLLKAAL_00450 1.3e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOLLKAAL_00451 9.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOLLKAAL_00452 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOLLKAAL_00453 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOLLKAAL_00454 4.6e-76 EGP Major facilitator Superfamily
IOLLKAAL_00455 2.2e-36
IOLLKAAL_00456 9.5e-16
IOLLKAAL_00457 0.0 nisT V ABC transporter
IOLLKAAL_00459 8.1e-114
IOLLKAAL_00460 2.7e-14 ropB K Helix-turn-helix domain
IOLLKAAL_00461 1.8e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOLLKAAL_00462 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOLLKAAL_00464 6e-79 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
IOLLKAAL_00465 8.2e-142 L oxidized base lesion DNA N-glycosylase activity
IOLLKAAL_00466 4.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOLLKAAL_00467 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOLLKAAL_00468 1.4e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOLLKAAL_00469 9.1e-248 clcA P chloride
IOLLKAAL_00470 1.6e-114
IOLLKAAL_00471 1e-45
IOLLKAAL_00472 6.6e-190 D nuclear chromosome segregation
IOLLKAAL_00473 5.8e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOLLKAAL_00474 4.6e-94 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IOLLKAAL_00475 2.2e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IOLLKAAL_00476 1.3e-85 folT S ECF transporter, substrate-specific component
IOLLKAAL_00477 4.9e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
IOLLKAAL_00478 2.8e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOLLKAAL_00479 4.4e-58 yabA L Involved in initiation control of chromosome replication
IOLLKAAL_00480 1e-151 holB 2.7.7.7 L DNA polymerase III
IOLLKAAL_00481 5e-51 yaaQ S Cyclic-di-AMP receptor
IOLLKAAL_00482 1.2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOLLKAAL_00483 9e-26 S Protein of unknown function (DUF2508)
IOLLKAAL_00484 6.9e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOLLKAAL_00485 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOLLKAAL_00486 3e-310 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOLLKAAL_00487 1e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOLLKAAL_00488 1e-40 S Protein conserved in bacteria
IOLLKAAL_00489 3.3e-147
IOLLKAAL_00490 3.9e-21
IOLLKAAL_00491 2.3e-113 rsmC 2.1.1.172 J Methyltransferase
IOLLKAAL_00492 2.7e-32
IOLLKAAL_00493 3.6e-128 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
IOLLKAAL_00494 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOLLKAAL_00495 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOLLKAAL_00496 1.5e-146 aatB ET ABC transporter substrate-binding protein
IOLLKAAL_00497 1.5e-115 glnQ 3.6.3.21 E ABC transporter
IOLLKAAL_00498 7.9e-109 glnP P ABC transporter permease
IOLLKAAL_00499 6.7e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOLLKAAL_00500 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOLLKAAL_00501 9.8e-100 nusG K Participates in transcription elongation, termination and antitermination
IOLLKAAL_00502 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOLLKAAL_00503 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOLLKAAL_00504 2.8e-188 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOLLKAAL_00505 1.3e-227 G Major Facilitator Superfamily
IOLLKAAL_00506 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOLLKAAL_00507 1.5e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IOLLKAAL_00508 1.7e-34
IOLLKAAL_00509 1e-88 yvrI K sigma factor activity
IOLLKAAL_00510 6e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOLLKAAL_00511 1.3e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOLLKAAL_00512 3.3e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOLLKAAL_00513 2.2e-287 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOLLKAAL_00514 4.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOLLKAAL_00515 7.3e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IOLLKAAL_00516 2.4e-187 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOLLKAAL_00517 8.4e-262 pepC 3.4.22.40 E Peptidase C1-like family
IOLLKAAL_00518 1.3e-195 nss M transferase activity, transferring glycosyl groups
IOLLKAAL_00519 7.4e-166 cpsJ S glycosyl transferase family 2
IOLLKAAL_00520 3.6e-25 UW Tetratricopeptide repeat
IOLLKAAL_00521 1e-229 EGP Sugar (and other) transporter
IOLLKAAL_00522 5.1e-69 S Iron-sulphur cluster biosynthesis
IOLLKAAL_00523 5.8e-287 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IOLLKAAL_00524 1.2e-210 pbuG S permease
IOLLKAAL_00525 2.6e-162 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IOLLKAAL_00526 1.1e-08 S RelB antitoxin
IOLLKAAL_00527 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOLLKAAL_00528 3.5e-288 clcA P chloride
IOLLKAAL_00529 6e-271 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOLLKAAL_00530 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOLLKAAL_00531 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOLLKAAL_00532 3.3e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOLLKAAL_00533 1.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOLLKAAL_00534 7.8e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOLLKAAL_00535 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IOLLKAAL_00536 2.4e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOLLKAAL_00537 1.2e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOLLKAAL_00538 1.6e-20 yaaA S S4 domain
IOLLKAAL_00539 1.2e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOLLKAAL_00540 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOLLKAAL_00541 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOLLKAAL_00542 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IOLLKAAL_00543 7.3e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOLLKAAL_00544 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOLLKAAL_00545 3.5e-158 corA P CorA-like Mg2+ transporter protein
IOLLKAAL_00546 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IOLLKAAL_00547 4.8e-76 rplI J Binds to the 23S rRNA
IOLLKAAL_00548 1.8e-243 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IOLLKAAL_00549 5e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IOLLKAAL_00550 2.2e-218 I Protein of unknown function (DUF2974)
IOLLKAAL_00551 0.0
IOLLKAAL_00553 5.6e-96 cadD P Cadmium resistance transporter
IOLLKAAL_00554 9.2e-59 cadX K Bacterial regulatory protein, arsR family
IOLLKAAL_00555 1.4e-181
IOLLKAAL_00556 4.6e-54
IOLLKAAL_00557 1.7e-131 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOLLKAAL_00558 8.6e-93
IOLLKAAL_00559 3.7e-83 repB EP Plasmid replication protein
IOLLKAAL_00560 4.6e-108 repB EP Plasmid replication protein
IOLLKAAL_00561 1.5e-31
IOLLKAAL_00562 1.6e-216 L Belongs to the 'phage' integrase family
IOLLKAAL_00563 1.1e-248 steT E amino acid
IOLLKAAL_00565 3.6e-134 S PAS domain
IOLLKAAL_00566 5.1e-72 K UTRA domain
IOLLKAAL_00567 2.2e-71 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
IOLLKAAL_00568 2.4e-126 agaC G PTS system sorbose-specific iic component
IOLLKAAL_00569 3.8e-124 G PTS system mannose/fructose/sorbose family IID component
IOLLKAAL_00570 2.6e-39 G PTS system fructose IIA component
IOLLKAAL_00571 9.8e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOLLKAAL_00572 0.0 GM domain, Protein
IOLLKAAL_00573 5.3e-144 pnuC H nicotinamide mononucleotide transporter
IOLLKAAL_00574 2.1e-91 S PAS domain
IOLLKAAL_00575 3.5e-241 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOLLKAAL_00576 2e-74 S Protein of unknown function (DUF3290)
IOLLKAAL_00577 4.4e-112 yviA S Protein of unknown function (DUF421)
IOLLKAAL_00578 3e-150 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IOLLKAAL_00579 3e-181 dnaQ 2.7.7.7 L EXOIII
IOLLKAAL_00580 9.3e-198 ltrA S Bacterial low temperature requirement A protein (LtrA)
IOLLKAAL_00581 2.9e-156 dkg S reductase
IOLLKAAL_00582 7.6e-152 endA F DNA RNA non-specific endonuclease
IOLLKAAL_00583 3.3e-280 pipD E Dipeptidase
IOLLKAAL_00584 3.8e-204 malK P ATPases associated with a variety of cellular activities
IOLLKAAL_00585 2.1e-157 gtsB P ABC-type sugar transport systems, permease components
IOLLKAAL_00586 1.1e-147 gtsC P Binding-protein-dependent transport system inner membrane component
IOLLKAAL_00587 5.1e-248 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
IOLLKAAL_00588 2.5e-239 G Bacterial extracellular solute-binding protein
IOLLKAAL_00589 2.9e-39 ypaA S Protein of unknown function (DUF1304)
IOLLKAAL_00590 3.9e-78 yybA 2.3.1.57 K Transcriptional regulator
IOLLKAAL_00591 1.1e-92 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IOLLKAAL_00592 1.1e-82 yjcF S Acetyltransferase (GNAT) domain
IOLLKAAL_00593 2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
IOLLKAAL_00594 1.9e-159 3.5.2.6 V Beta-lactamase enzyme family
IOLLKAAL_00595 1.1e-95 yobS K Bacterial regulatory proteins, tetR family
IOLLKAAL_00596 0.0 ydgH S MMPL family
IOLLKAAL_00597 1.3e-145 cof S haloacid dehalogenase-like hydrolase
IOLLKAAL_00598 9.9e-126 S SNARE associated Golgi protein
IOLLKAAL_00599 1.6e-177
IOLLKAAL_00600 9.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IOLLKAAL_00601 5.6e-155 hipB K Helix-turn-helix
IOLLKAAL_00602 6.3e-156 I alpha/beta hydrolase fold
IOLLKAAL_00603 5.3e-107 yjbF S SNARE associated Golgi protein
IOLLKAAL_00604 2.3e-101 J Acetyltransferase (GNAT) domain
IOLLKAAL_00605 2.5e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOLLKAAL_00606 5.4e-200 S Sterol carrier protein domain
IOLLKAAL_00607 1.6e-165 arbZ I Acyltransferase
IOLLKAAL_00608 8.8e-116 ywnB S NAD(P)H-binding
IOLLKAAL_00609 4.7e-143 ropB K Helix-turn-helix domain
IOLLKAAL_00610 9.4e-200 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
IOLLKAAL_00611 8.5e-173 yxaM EGP Major Facilitator Superfamily
IOLLKAAL_00612 9.3e-132 S Protein of unknown function (DUF975)
IOLLKAAL_00613 1.5e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOLLKAAL_00614 1.6e-154 yitS S EDD domain protein, DegV family
IOLLKAAL_00615 3.5e-17
IOLLKAAL_00616 2.7e-291 V ABC-type multidrug transport system, ATPase and permease components
IOLLKAAL_00617 3.7e-140 ropB K Helix-turn-helix domain
IOLLKAAL_00618 0.0 tetP J elongation factor G
IOLLKAAL_00619 7.3e-242 clcA P chloride
IOLLKAAL_00620 0.0 pepO 3.4.24.71 O Peptidase family M13
IOLLKAAL_00621 2.7e-114 ropB K Helix-turn-helix XRE-family like proteins
IOLLKAAL_00622 2.5e-197 L COG2826 Transposase and inactivated derivatives, IS30 family
IOLLKAAL_00623 2.3e-165 P CorA-like Mg2+ transporter protein
IOLLKAAL_00625 4.2e-40 S Transglycosylase associated protein
IOLLKAAL_00626 5.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
IOLLKAAL_00627 0.0 L Helicase C-terminal domain protein
IOLLKAAL_00628 7.7e-139 S Alpha beta hydrolase
IOLLKAAL_00629 5.1e-07
IOLLKAAL_00630 7.2e-16
IOLLKAAL_00631 2.4e-26
IOLLKAAL_00632 1.9e-168 K AI-2E family transporter
IOLLKAAL_00633 1.9e-253 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
IOLLKAAL_00634 3.1e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOLLKAAL_00635 1.5e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
IOLLKAAL_00636 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOLLKAAL_00637 0.0 S domain, Protein
IOLLKAAL_00638 3.2e-65 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
IOLLKAAL_00639 3.6e-123 L restriction endonuclease
IOLLKAAL_00640 2.1e-134 mrr L restriction endonuclease
IOLLKAAL_00641 1.6e-62 2.5.1.74 H UbiA prenyltransferase family
IOLLKAAL_00642 1.9e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOLLKAAL_00643 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOLLKAAL_00644 5.8e-115 hlyIII S protein, hemolysin III
IOLLKAAL_00645 4.7e-149 DegV S Uncharacterised protein, DegV family COG1307
IOLLKAAL_00646 1.6e-35 yozE S Belongs to the UPF0346 family
IOLLKAAL_00647 3.1e-262 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IOLLKAAL_00648 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOLLKAAL_00649 1.8e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOLLKAAL_00650 1.8e-153 dprA LU DNA protecting protein DprA
IOLLKAAL_00651 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOLLKAAL_00652 1.5e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOLLKAAL_00653 1.3e-168 xerC D Phage integrase, N-terminal SAM-like domain
IOLLKAAL_00654 4.3e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOLLKAAL_00655 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOLLKAAL_00656 1.1e-177 lacX 5.1.3.3 G Aldose 1-epimerase
IOLLKAAL_00657 2.3e-97 K LysR substrate binding domain
IOLLKAAL_00658 1.2e-100 S LexA-binding, inner membrane-associated putative hydrolase
IOLLKAAL_00660 1.9e-72
IOLLKAAL_00661 2.6e-178 MA20_14895 S Conserved hypothetical protein 698
IOLLKAAL_00662 5.3e-273 lsa S ABC transporter
IOLLKAAL_00663 4.1e-83 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
IOLLKAAL_00664 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IOLLKAAL_00665 1.1e-135 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
IOLLKAAL_00666 3.8e-64 S Protein of unknown function (DUF3021)
IOLLKAAL_00667 2.6e-71 K LytTr DNA-binding domain
IOLLKAAL_00668 6.3e-18 sprD D Domain of Unknown Function (DUF1542)
IOLLKAAL_00669 2.6e-115 papP P ABC transporter, permease protein
IOLLKAAL_00670 1.3e-106 P ABC transporter permease
IOLLKAAL_00671 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOLLKAAL_00672 7.2e-142 cjaA ET ABC transporter substrate-binding protein
IOLLKAAL_00673 7.1e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
IOLLKAAL_00674 4.6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOLLKAAL_00675 9.2e-247 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOLLKAAL_00676 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
IOLLKAAL_00677 7.3e-124 skfE V ATPases associated with a variety of cellular activities
IOLLKAAL_00678 3.5e-146
IOLLKAAL_00679 4.1e-142
IOLLKAAL_00680 5.4e-36 L PFAM Integrase catalytic region
IOLLKAAL_00681 5.8e-149
IOLLKAAL_00683 3.7e-288 V ABC transporter transmembrane region
IOLLKAAL_00684 2.9e-39
IOLLKAAL_00685 1.1e-62
IOLLKAAL_00686 1.4e-14 ywnB S NAD(P)H-binding
IOLLKAAL_00687 1.5e-75 L transposase activity
IOLLKAAL_00688 4.7e-22
IOLLKAAL_00689 1.4e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOLLKAAL_00690 2.4e-130
IOLLKAAL_00691 1.4e-173
IOLLKAAL_00692 3.9e-262 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
IOLLKAAL_00693 8.5e-51 ybjQ S Belongs to the UPF0145 family
IOLLKAAL_00694 4.2e-176 XK27_05540 S DUF218 domain
IOLLKAAL_00695 1.2e-149 yxeH S hydrolase
IOLLKAAL_00696 2e-302 I Protein of unknown function (DUF2974)
IOLLKAAL_00697 1.2e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOLLKAAL_00698 9.9e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOLLKAAL_00699 5.7e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOLLKAAL_00700 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOLLKAAL_00701 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IOLLKAAL_00702 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOLLKAAL_00703 5.5e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOLLKAAL_00704 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IOLLKAAL_00705 2.8e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOLLKAAL_00706 2.9e-104 pncA Q Isochorismatase family
IOLLKAAL_00707 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IOLLKAAL_00708 8.4e-215 M Glycosyl transferases group 1
IOLLKAAL_00710 1.5e-129 K response regulator
IOLLKAAL_00711 0.0 vicK 2.7.13.3 T Histidine kinase
IOLLKAAL_00712 3e-251 yycH S YycH protein
IOLLKAAL_00713 6.7e-145 yycI S YycH protein
IOLLKAAL_00714 1.1e-147 vicX 3.1.26.11 S domain protein
IOLLKAAL_00715 6.4e-176 htrA 3.4.21.107 O serine protease
IOLLKAAL_00716 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOLLKAAL_00717 2.1e-109 P Cobalt transport protein
IOLLKAAL_00718 6.2e-249 cbiO1 S ABC transporter, ATP-binding protein
IOLLKAAL_00719 6.1e-97 S ABC-type cobalt transport system, permease component
IOLLKAAL_00720 2.8e-168 K helix_turn_helix, arabinose operon control protein
IOLLKAAL_00721 2e-163 htpX O Belongs to the peptidase M48B family
IOLLKAAL_00722 3.2e-90 lemA S LemA family
IOLLKAAL_00723 6e-181 ybiR P Citrate transporter
IOLLKAAL_00724 3.5e-70 S Iron-sulphur cluster biosynthesis
IOLLKAAL_00725 1.7e-16
IOLLKAAL_00726 5.6e-118
IOLLKAAL_00728 2.4e-245 ydaM M Glycosyl transferase
IOLLKAAL_00729 8.1e-210 G Glycosyl hydrolases family 8
IOLLKAAL_00730 4.5e-120 yfbR S HD containing hydrolase-like enzyme
IOLLKAAL_00731 3.7e-176 L HNH nucleases
IOLLKAAL_00732 2e-45
IOLLKAAL_00733 7.3e-138 glnQ E ABC transporter, ATP-binding protein
IOLLKAAL_00734 6.4e-301 glnP P ABC transporter permease
IOLLKAAL_00735 5e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IOLLKAAL_00736 4.4e-64 yeaO S Protein of unknown function, DUF488
IOLLKAAL_00737 3.6e-124 terC P Integral membrane protein TerC family
IOLLKAAL_00738 9.2e-87 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IOLLKAAL_00739 5.1e-133 cobB K SIR2 family
IOLLKAAL_00740 2.6e-80
IOLLKAAL_00741 4.8e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOLLKAAL_00742 2.1e-123 yugP S Putative neutral zinc metallopeptidase
IOLLKAAL_00743 2.2e-176 S Alpha/beta hydrolase of unknown function (DUF915)
IOLLKAAL_00744 7.7e-140 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOLLKAAL_00746 4.8e-158 ypuA S Protein of unknown function (DUF1002)
IOLLKAAL_00747 8e-154 epsV 2.7.8.12 S glycosyl transferase family 2
IOLLKAAL_00748 1.1e-124 S Alpha/beta hydrolase family
IOLLKAAL_00749 9.1e-62
IOLLKAAL_00750 1.6e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOLLKAAL_00751 1.6e-239 cycA E Amino acid permease
IOLLKAAL_00752 7.6e-115 luxT K Bacterial regulatory proteins, tetR family
IOLLKAAL_00753 4.2e-126
IOLLKAAL_00754 8.3e-266 S Cysteine-rich secretory protein family
IOLLKAAL_00755 4.8e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IOLLKAAL_00756 6.8e-77
IOLLKAAL_00757 1.2e-270 yjcE P Sodium proton antiporter
IOLLKAAL_00758 8.9e-169 yibE S overlaps another CDS with the same product name
IOLLKAAL_00759 1.2e-119 yibF S overlaps another CDS with the same product name
IOLLKAAL_00760 9.6e-155 I alpha/beta hydrolase fold
IOLLKAAL_00761 0.0 G Belongs to the glycosyl hydrolase 31 family
IOLLKAAL_00762 1.5e-129 XK27_08435 K UTRA
IOLLKAAL_00763 5.5e-217 agaS G SIS domain
IOLLKAAL_00764 1.4e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOLLKAAL_00765 6.7e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
IOLLKAAL_00766 3.4e-129 XK27_08455 G PTS system sorbose-specific iic component
IOLLKAAL_00767 7.1e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
IOLLKAAL_00768 3.6e-67 2.7.1.191 G PTS system fructose IIA component
IOLLKAAL_00769 1.3e-218 S zinc-ribbon domain
IOLLKAAL_00770 4.8e-87 ntd 2.4.2.6 F Nucleoside
IOLLKAAL_00771 3.4e-100 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOLLKAAL_00772 1.1e-130 XK27_08440 K UTRA domain
IOLLKAAL_00773 3.4e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
IOLLKAAL_00774 1e-87 uspA T universal stress protein
IOLLKAAL_00776 9.8e-169 phnD P Phosphonate ABC transporter
IOLLKAAL_00777 1.9e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IOLLKAAL_00778 5.4e-131 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IOLLKAAL_00779 7.1e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IOLLKAAL_00780 1.9e-83
IOLLKAAL_00781 4e-275 S Calcineurin-like phosphoesterase
IOLLKAAL_00782 0.0 asnB 6.3.5.4 E Asparagine synthase
IOLLKAAL_00783 3.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
IOLLKAAL_00784 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IOLLKAAL_00785 3.1e-130 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOLLKAAL_00786 2.9e-105 S Iron-sulfur cluster assembly protein
IOLLKAAL_00787 6.4e-229 XK27_04775 S PAS domain
IOLLKAAL_00788 1.2e-227 yttB EGP Major facilitator Superfamily
IOLLKAAL_00789 1.6e-185 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
IOLLKAAL_00790 5.3e-184 D nuclear chromosome segregation
IOLLKAAL_00791 2.6e-135 rpl K Helix-turn-helix domain, rpiR family
IOLLKAAL_00792 1.3e-168 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
IOLLKAAL_00793 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOLLKAAL_00794 0.0 pepO 3.4.24.71 O Peptidase family M13
IOLLKAAL_00795 0.0 S Bacterial membrane protein, YfhO
IOLLKAAL_00796 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IOLLKAAL_00797 0.0 kup P Transport of potassium into the cell
IOLLKAAL_00798 0.0 kup P Transport of potassium into the cell
IOLLKAAL_00799 1e-72
IOLLKAAL_00800 5.5e-115
IOLLKAAL_00801 4.2e-27
IOLLKAAL_00802 8.2e-35 S Protein of unknown function (DUF2922)
IOLLKAAL_00803 2.2e-213 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOLLKAAL_00804 2.5e-231 lysA2 M Glycosyl hydrolases family 25
IOLLKAAL_00805 3.6e-143 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
IOLLKAAL_00806 0.0 yjbQ P TrkA C-terminal domain protein
IOLLKAAL_00807 1.4e-178 S Oxidoreductase family, NAD-binding Rossmann fold
IOLLKAAL_00808 9.5e-141
IOLLKAAL_00809 2.9e-148
IOLLKAAL_00810 2.4e-74 S PAS domain
IOLLKAAL_00811 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOLLKAAL_00812 2.1e-45 S HicB_like antitoxin of bacterial toxin-antitoxin system
IOLLKAAL_00813 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOLLKAAL_00814 3.4e-71 2.4.1.83 GT2 S GtrA-like protein
IOLLKAAL_00815 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IOLLKAAL_00816 1.2e-118
IOLLKAAL_00817 1.2e-152 glcU U sugar transport
IOLLKAAL_00818 2.2e-170 yqhA G Aldose 1-epimerase
IOLLKAAL_00819 2.3e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOLLKAAL_00820 1.9e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOLLKAAL_00821 0.0 XK27_08315 M Sulfatase
IOLLKAAL_00822 4.8e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOLLKAAL_00824 7.2e-258 pepC 3.4.22.40 E aminopeptidase
IOLLKAAL_00825 3.3e-48 oppA E ABC transporter, substratebinding protein
IOLLKAAL_00826 1.9e-137 oppA E ABC transporter, substratebinding protein
IOLLKAAL_00827 3.9e-125 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOLLKAAL_00828 6.2e-148 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOLLKAAL_00829 6.7e-17 oppD P Belongs to the ABC transporter superfamily
IOLLKAAL_00830 1.4e-114 oppD P Belongs to the ABC transporter superfamily
IOLLKAAL_00831 4.8e-131 oppF P Belongs to the ABC transporter superfamily
IOLLKAAL_00832 9.8e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOLLKAAL_00833 3.7e-254 pepC 3.4.22.40 E aminopeptidase
IOLLKAAL_00834 3.8e-31
IOLLKAAL_00835 9.1e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOLLKAAL_00836 2.2e-51 hsp O Belongs to the small heat shock protein (HSP20) family
IOLLKAAL_00837 2.4e-291 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOLLKAAL_00838 7.5e-83
IOLLKAAL_00839 8.2e-241 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOLLKAAL_00840 5.2e-130 yydK K UTRA
IOLLKAAL_00841 4.6e-70 S Domain of unknown function (DUF3284)
IOLLKAAL_00842 3.1e-305 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOLLKAAL_00843 2.1e-134 gmuR K UTRA
IOLLKAAL_00844 1.5e-50 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
IOLLKAAL_00845 2.1e-41
IOLLKAAL_00846 3.4e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IOLLKAAL_00847 4.6e-263 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOLLKAAL_00848 1.8e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOLLKAAL_00849 5.5e-158 ypbG 2.7.1.2 GK ROK family
IOLLKAAL_00850 1.8e-116
IOLLKAAL_00852 1.2e-114 E Belongs to the SOS response-associated peptidase family
IOLLKAAL_00853 1.2e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOLLKAAL_00854 5.6e-91 comEB 3.5.4.12 F MafB19-like deaminase
IOLLKAAL_00855 4e-99 S TPM domain
IOLLKAAL_00856 8.5e-182 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IOLLKAAL_00857 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOLLKAAL_00858 3.6e-148 tatD L hydrolase, TatD family
IOLLKAAL_00859 1.2e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOLLKAAL_00860 1.2e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOLLKAAL_00861 2.2e-35 veg S Biofilm formation stimulator VEG
IOLLKAAL_00862 1.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IOLLKAAL_00863 4.1e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOLLKAAL_00864 1.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOLLKAAL_00865 3.8e-176 yvdE K helix_turn _helix lactose operon repressor
IOLLKAAL_00866 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IOLLKAAL_00867 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IOLLKAAL_00868 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IOLLKAAL_00869 8.1e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IOLLKAAL_00870 2.3e-209 msmX P Belongs to the ABC transporter superfamily
IOLLKAAL_00871 2.8e-216 malE G Bacterial extracellular solute-binding protein
IOLLKAAL_00872 2.5e-253 malF P Binding-protein-dependent transport system inner membrane component
IOLLKAAL_00873 2.4e-153 malG P ABC transporter permease
IOLLKAAL_00874 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
IOLLKAAL_00875 5.1e-267 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOLLKAAL_00876 4e-69 S Domain of unknown function (DUF1934)
IOLLKAAL_00877 2.5e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOLLKAAL_00878 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOLLKAAL_00879 2.9e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOLLKAAL_00880 3.5e-236 pbuX F xanthine permease
IOLLKAAL_00881 1.2e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOLLKAAL_00882 8e-132 K Psort location CytoplasmicMembrane, score
IOLLKAAL_00883 3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IOLLKAAL_00884 1.1e-56 hxlR K Transcriptional regulator, HxlR family
IOLLKAAL_00885 3.7e-148 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IOLLKAAL_00886 1.8e-28 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IOLLKAAL_00887 3.2e-12
IOLLKAAL_00888 5.6e-107 K transcriptional regulator
IOLLKAAL_00889 2e-94 yxkA S Phosphatidylethanolamine-binding protein
IOLLKAAL_00890 1e-171 K Helix-turn-helix
IOLLKAAL_00891 1.2e-111 1.6.5.2 S NADPH-dependent FMN reductase
IOLLKAAL_00892 3.9e-93 K Bacterial regulatory proteins, tetR family
IOLLKAAL_00893 2.2e-56 yjdF S Protein of unknown function (DUF2992)
IOLLKAAL_00894 2.1e-214 hsdM 2.1.1.72 V type I restriction-modification system
IOLLKAAL_00895 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IOLLKAAL_00896 6.5e-232 S Tetratricopeptide repeat protein
IOLLKAAL_00897 6.7e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOLLKAAL_00898 3.4e-244 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IOLLKAAL_00899 6e-219 rpsA 1.17.7.4 J Ribosomal protein S1
IOLLKAAL_00900 2.1e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IOLLKAAL_00901 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOLLKAAL_00902 3.9e-62 M Lysin motif
IOLLKAAL_00903 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOLLKAAL_00904 3.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOLLKAAL_00905 9.1e-133 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOLLKAAL_00906 1.8e-62 ribT K acetyltransferase
IOLLKAAL_00907 1.1e-164 xerD D recombinase XerD
IOLLKAAL_00908 1.2e-166 cvfB S S1 domain
IOLLKAAL_00909 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IOLLKAAL_00910 3e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOLLKAAL_00911 0.0 dnaE 2.7.7.7 L DNA polymerase
IOLLKAAL_00912 2e-26 S Protein of unknown function (DUF2929)
IOLLKAAL_00913 1.6e-304 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IOLLKAAL_00914 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IOLLKAAL_00915 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
IOLLKAAL_00916 3.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOLLKAAL_00917 3e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOLLKAAL_00918 0.0 oatA I Acyltransferase
IOLLKAAL_00919 2.7e-241 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOLLKAAL_00920 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOLLKAAL_00921 7e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
IOLLKAAL_00922 1.6e-90 dedA 3.1.3.1 S SNARE associated Golgi protein
IOLLKAAL_00923 3.6e-151 xerD L Phage integrase, N-terminal SAM-like domain
IOLLKAAL_00924 1.8e-116 GM NmrA-like family
IOLLKAAL_00925 3.8e-246 yagE E amino acid
IOLLKAAL_00926 1.3e-70 S PFAM Archaeal ATPase
IOLLKAAL_00927 3e-34 S PFAM Archaeal ATPase
IOLLKAAL_00928 6.9e-49 S PFAM Archaeal ATPase
IOLLKAAL_00929 4.9e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOLLKAAL_00931 3.4e-140 H Nodulation protein S (NodS)
IOLLKAAL_00932 4.6e-269 mntH P H( )-stimulated, divalent metal cation uptake system
IOLLKAAL_00933 6.2e-54 yitW S Iron-sulfur cluster assembly protein
IOLLKAAL_00934 3.4e-274 sufB O assembly protein SufB
IOLLKAAL_00935 2.7e-79 nifU C SUF system FeS assembly protein, NifU family
IOLLKAAL_00936 7.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOLLKAAL_00937 2.7e-227 sufD O FeS assembly protein SufD
IOLLKAAL_00938 1.7e-145 sufC O FeS assembly ATPase SufC
IOLLKAAL_00939 2.1e-244 brnQ U Component of the transport system for branched-chain amino acids
IOLLKAAL_00940 2.4e-72 S Putative adhesin
IOLLKAAL_00941 2.7e-25 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IOLLKAAL_00942 4.4e-123 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IOLLKAAL_00943 2.4e-89 S Peptidase propeptide and YPEB domain
IOLLKAAL_00944 3.4e-239 T GHKL domain
IOLLKAAL_00945 8.2e-128 T Transcriptional regulatory protein, C terminal
IOLLKAAL_00946 2e-117 3.6.1.55 F NUDIX domain
IOLLKAAL_00947 1.4e-107 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOLLKAAL_00948 3e-55 S reductase
IOLLKAAL_00949 8.6e-12 S reductase
IOLLKAAL_00950 8.4e-109 S Protein of unknown function (DUF1211)
IOLLKAAL_00951 6.4e-199 sprD D Domain of Unknown Function (DUF1542)
IOLLKAAL_00952 3.8e-211 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
IOLLKAAL_00953 3.9e-82 lacA 3.2.1.23 G -beta-galactosidase
IOLLKAAL_00954 8.7e-284 dtpT U amino acid peptide transporter
IOLLKAAL_00955 1.6e-279 pipD E Peptidase family C69
IOLLKAAL_00956 1.3e-216 naiP EGP Major facilitator Superfamily
IOLLKAAL_00957 1.7e-154 S Alpha beta hydrolase
IOLLKAAL_00958 8.7e-67 K Transcriptional regulator, MarR family
IOLLKAAL_00959 8.5e-299 XK27_09600 V ABC transporter, ATP-binding protein
IOLLKAAL_00960 0.0 V ABC transporter transmembrane region
IOLLKAAL_00961 1.4e-147 glnH ET ABC transporter
IOLLKAAL_00962 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOLLKAAL_00963 3.1e-150 glnH ET ABC transporter
IOLLKAAL_00964 2.4e-110 gluC P ABC transporter permease
IOLLKAAL_00965 5.7e-107 glnP P ABC transporter permease
IOLLKAAL_00966 1.9e-65
IOLLKAAL_00967 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IOLLKAAL_00968 2e-129 treR K UTRA
IOLLKAAL_00969 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOLLKAAL_00970 6.4e-76 S Putative adhesin
IOLLKAAL_00972 2.3e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IOLLKAAL_00974 9.2e-205 2.7.13.3 T GHKL domain
IOLLKAAL_00976 3e-147 arbV 2.3.1.51 I Acyl-transferase
IOLLKAAL_00977 1.6e-154 arbx M Glycosyl transferase family 8
IOLLKAAL_00978 1.1e-183 arbY M Glycosyl transferase family 8
IOLLKAAL_00979 1.4e-186 arbY M Glycosyl transferase family 8
IOLLKAAL_00980 4.7e-165 arbZ I Phosphate acyltransferases
IOLLKAAL_00981 1e-246 yhjX_2 P Major Facilitator Superfamily
IOLLKAAL_00982 2.2e-249 yhjX_2 P Major Facilitator Superfamily
IOLLKAAL_00983 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IOLLKAAL_00984 1.2e-63 S Peptidase propeptide and YPEB domain
IOLLKAAL_00985 1.6e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IOLLKAAL_00986 2.1e-134 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IOLLKAAL_00987 3.4e-242 brnQ U Component of the transport system for branched-chain amino acids
IOLLKAAL_00988 0.0 1.3.5.4 C FAD binding domain
IOLLKAAL_00989 3.6e-171 K LysR substrate binding domain
IOLLKAAL_00990 7.8e-299 E amino acid
IOLLKAAL_00991 0.0 3.1.31.1 M domain protein
IOLLKAAL_00992 1.8e-124 infB UW LPXTG-motif cell wall anchor domain protein
IOLLKAAL_00994 6.3e-31
IOLLKAAL_00995 1.3e-11
IOLLKAAL_00996 9e-220 KQ helix_turn_helix, mercury resistance
IOLLKAAL_00997 5.4e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOLLKAAL_00998 1.1e-164 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOLLKAAL_00999 6.7e-118 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IOLLKAAL_01000 5.9e-188 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOLLKAAL_01002 1.5e-124
IOLLKAAL_01003 4e-86
IOLLKAAL_01004 2e-12 yttA 2.7.13.3 S Pfam Transposase IS66
IOLLKAAL_01005 3.2e-39 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IOLLKAAL_01006 2.4e-191 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOLLKAAL_01007 5.8e-26 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IOLLKAAL_01008 9.5e-235 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOLLKAAL_01009 1.2e-94 2.7.1.202 GKT Mga helix-turn-helix domain
IOLLKAAL_01010 7.7e-260 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IOLLKAAL_01011 1.2e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IOLLKAAL_01012 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOLLKAAL_01013 6.7e-156 asp3 S Accessory Sec secretory system ASP3
IOLLKAAL_01014 6.2e-301 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
IOLLKAAL_01015 5.1e-292 asp1 S Accessory Sec system protein Asp1
IOLLKAAL_01016 1.3e-213 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
IOLLKAAL_01017 6.2e-307 gadC E Contains amino acid permease domain
IOLLKAAL_01018 2.4e-43 UW LPXTG-motif cell wall anchor domain protein
IOLLKAAL_01019 3.8e-54 K Acetyltransferase (GNAT) domain
IOLLKAAL_01020 8.5e-248 ynbB 4.4.1.1 P aluminum resistance
IOLLKAAL_01021 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
IOLLKAAL_01022 8e-282 E Amino acid permease
IOLLKAAL_01023 1.2e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOLLKAAL_01024 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
IOLLKAAL_01025 1.3e-85 fhaB M Rib/alpha-like repeat
IOLLKAAL_01026 5.5e-71 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOLLKAAL_01027 4.7e-155 EG EamA-like transporter family
IOLLKAAL_01028 0.0 oppA E ABC transporter substrate-binding protein
IOLLKAAL_01029 2.6e-161 2.7.1.191 G PTS system sorbose subfamily IIB component
IOLLKAAL_01030 1.4e-139 G PTS system sorbose-specific iic component
IOLLKAAL_01031 1.5e-144 G PTS system mannose/fructose/sorbose family IID component
IOLLKAAL_01032 3.4e-62
IOLLKAAL_01033 1.4e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOLLKAAL_01034 1.9e-203 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IOLLKAAL_01035 9.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOLLKAAL_01037 3.4e-99 S Rib/alpha-like repeat
IOLLKAAL_01038 9.9e-67 S Domain of unknown function DUF1828
IOLLKAAL_01039 2.5e-68
IOLLKAAL_01040 3.9e-39
IOLLKAAL_01041 3.7e-81 mutT 3.6.1.55 F NUDIX domain
IOLLKAAL_01042 6.8e-84
IOLLKAAL_01044 5.9e-101 htpX O Peptidase family M48
IOLLKAAL_01045 3.3e-106 S AAA domain, putative AbiEii toxin, Type IV TA system
IOLLKAAL_01046 2.3e-109
IOLLKAAL_01047 3.4e-61
IOLLKAAL_01059 9.9e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
IOLLKAAL_01060 1.5e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
IOLLKAAL_01061 1.3e-182 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOLLKAAL_01062 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOLLKAAL_01063 7.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOLLKAAL_01064 1.9e-163 coaA 2.7.1.33 F Pantothenic acid kinase
IOLLKAAL_01065 1.4e-101 E GDSL-like Lipase/Acylhydrolase
IOLLKAAL_01066 3.3e-119 yvpB S Peptidase_C39 like family
IOLLKAAL_01067 0.0 helD 3.6.4.12 L DNA helicase
IOLLKAAL_01068 2.1e-117 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IOLLKAAL_01070 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
IOLLKAAL_01071 9.6e-144 rpiR1 K Helix-turn-helix domain, rpiR family
IOLLKAAL_01072 1.5e-126 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IOLLKAAL_01073 0.0 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
IOLLKAAL_01074 1.9e-149 xth 3.1.11.2 L exodeoxyribonuclease III
IOLLKAAL_01075 1.3e-52
IOLLKAAL_01076 2.8e-26
IOLLKAAL_01077 8.8e-124 pgm3 G Phosphoglycerate mutase family
IOLLKAAL_01078 0.0 V FtsX-like permease family
IOLLKAAL_01079 6.3e-134 cysA V ABC transporter, ATP-binding protein
IOLLKAAL_01080 6.2e-279 E amino acid
IOLLKAAL_01081 7.7e-121 V ABC-2 type transporter
IOLLKAAL_01082 4.2e-122 V Transport permease protein
IOLLKAAL_01083 7e-136 V ABC transporter
IOLLKAAL_01084 1.3e-74
IOLLKAAL_01086 3.4e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOLLKAAL_01087 5.3e-231 S Putative peptidoglycan binding domain
IOLLKAAL_01088 6.9e-119 M NlpC P60 family protein
IOLLKAAL_01089 1.4e-98 gmk2 2.7.4.8 F Guanylate kinase
IOLLKAAL_01090 5.3e-44
IOLLKAAL_01091 4.6e-272 S O-antigen ligase like membrane protein
IOLLKAAL_01092 1.4e-110
IOLLKAAL_01093 7.7e-82 nrdI F Belongs to the NrdI family
IOLLKAAL_01094 6.4e-176 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOLLKAAL_01095 1.3e-79
IOLLKAAL_01096 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOLLKAAL_01097 4e-40
IOLLKAAL_01098 2.8e-79 S Threonine/Serine exporter, ThrE
IOLLKAAL_01099 2.4e-136 thrE S Putative threonine/serine exporter
IOLLKAAL_01100 3.6e-285 S ABC transporter
IOLLKAAL_01101 4.3e-62
IOLLKAAL_01102 6.2e-39
IOLLKAAL_01103 9e-209 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOLLKAAL_01104 0.0 pepF E oligoendopeptidase F
IOLLKAAL_01105 1.2e-256 lctP C L-lactate permease
IOLLKAAL_01106 8.7e-134 znuB U ABC 3 transport family
IOLLKAAL_01107 1.6e-117 fhuC P ABC transporter
IOLLKAAL_01108 1.2e-158 psaA P Belongs to the bacterial solute-binding protein 9 family
IOLLKAAL_01109 2.1e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOLLKAAL_01110 4.7e-140 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
IOLLKAAL_01111 0.0 2.7.7.7 M domain protein
IOLLKAAL_01112 5.4e-67 S YSIRK type signal peptide
IOLLKAAL_01113 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
IOLLKAAL_01114 1.2e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOLLKAAL_01115 1.4e-136 fruR K DeoR C terminal sensor domain
IOLLKAAL_01116 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IOLLKAAL_01117 1.7e-221 natB CP ABC-2 family transporter protein
IOLLKAAL_01118 4.4e-166 natA S ABC transporter, ATP-binding protein
IOLLKAAL_01119 1.3e-142 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IOLLKAAL_01120 2.2e-306 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOLLKAAL_01121 4.8e-205 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
IOLLKAAL_01122 7.4e-121 K response regulator
IOLLKAAL_01123 0.0 V ABC transporter
IOLLKAAL_01124 7.1e-298 V ABC transporter, ATP-binding protein
IOLLKAAL_01125 3.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
IOLLKAAL_01126 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOLLKAAL_01127 1.9e-42 yyzM S Bacterial protein of unknown function (DUF951)
IOLLKAAL_01128 2.2e-154 spo0J K Belongs to the ParB family
IOLLKAAL_01129 9.7e-138 soj D Sporulation initiation inhibitor
IOLLKAAL_01130 1.1e-142 noc K Belongs to the ParB family
IOLLKAAL_01131 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IOLLKAAL_01132 6.4e-96 cvpA S Colicin V production protein
IOLLKAAL_01133 4e-178 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOLLKAAL_01134 5.7e-149 3.1.3.48 T Tyrosine phosphatase family
IOLLKAAL_01135 1.1e-200 4.2.1.126 S Bacterial protein of unknown function (DUF871)
IOLLKAAL_01136 3.7e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
IOLLKAAL_01137 2.2e-96 nqr 1.5.1.36 S reductase
IOLLKAAL_01138 1e-108 K WHG domain
IOLLKAAL_01139 1.8e-37
IOLLKAAL_01140 1.7e-273 pipD E Dipeptidase
IOLLKAAL_01141 4.1e-294 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOLLKAAL_01142 0.0 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOLLKAAL_01143 5.1e-156 K CAT RNA binding domain
IOLLKAAL_01144 3.1e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IOLLKAAL_01145 1.2e-183 hrtB V ABC transporter permease
IOLLKAAL_01146 2.4e-92 ygfC K Bacterial regulatory proteins, tetR family
IOLLKAAL_01147 4.6e-111 G phosphoglycerate mutase
IOLLKAAL_01148 3.6e-114 G Phosphoglycerate mutase family
IOLLKAAL_01149 1e-139 aroD S Alpha/beta hydrolase family
IOLLKAAL_01150 5.4e-141 S Belongs to the UPF0246 family
IOLLKAAL_01151 2.6e-40
IOLLKAAL_01152 1.3e-128
IOLLKAAL_01153 3.9e-162 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IOLLKAAL_01154 1.6e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOLLKAAL_01155 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IOLLKAAL_01156 5.3e-144 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
IOLLKAAL_01157 6.3e-154 ybbH_2 K Helix-turn-helix domain, rpiR family
IOLLKAAL_01158 8e-156 2.7.7.12 C Domain of unknown function (DUF4931)
IOLLKAAL_01159 4.3e-71 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
IOLLKAAL_01160 4e-156
IOLLKAAL_01161 1.3e-75 mdtG EGP Major Facilitator Superfamily
IOLLKAAL_01162 2.6e-138 mdtG EGP Major facilitator Superfamily
IOLLKAAL_01163 1.7e-125 puuD S peptidase C26
IOLLKAAL_01164 6.2e-296 V ABC transporter transmembrane region
IOLLKAAL_01165 2.5e-86 ymdB S Macro domain protein
IOLLKAAL_01166 6.5e-36
IOLLKAAL_01167 0.0 scrA 2.7.1.199, 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
IOLLKAAL_01168 2.9e-300 scrB 3.2.1.26 GH32 G invertase
IOLLKAAL_01169 6.6e-139 scrR K Transcriptional regulator, LacI family
IOLLKAAL_01170 4.4e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
IOLLKAAL_01171 4.4e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOLLKAAL_01172 7.8e-131 cobQ S glutamine amidotransferase
IOLLKAAL_01173 6e-255 yfnA E Amino Acid
IOLLKAAL_01174 3.9e-162 EG EamA-like transporter family
IOLLKAAL_01175 9e-192 asnA 6.3.1.1 F aspartate--ammonia ligase
IOLLKAAL_01176 5.9e-234 steT_1 E amino acid
IOLLKAAL_01177 3.1e-138 puuD S peptidase C26
IOLLKAAL_01178 3.5e-231 yifK E Amino acid permease
IOLLKAAL_01179 1.5e-253 yifK E Amino acid permease
IOLLKAAL_01180 1.8e-65 manO S Domain of unknown function (DUF956)
IOLLKAAL_01181 3.3e-172 manN G system, mannose fructose sorbose family IID component
IOLLKAAL_01182 1.3e-124 manY G PTS system
IOLLKAAL_01183 7.5e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IOLLKAAL_01184 8.6e-223 L Putative transposase DNA-binding domain
IOLLKAAL_01185 1.2e-143 K LytTr DNA-binding domain
IOLLKAAL_01186 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOLLKAAL_01187 4.9e-105 M Transport protein ComB
IOLLKAAL_01188 3.2e-20 S Bacteriocin class II with double-glycine leader peptide
IOLLKAAL_01191 6.7e-155 2.7.13.3 T GHKL domain
IOLLKAAL_01192 4.8e-137 K LytTr DNA-binding domain
IOLLKAAL_01193 3.5e-135 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IOLLKAAL_01194 2.9e-148 K Helix-turn-helix XRE-family like proteins
IOLLKAAL_01195 1.2e-82
IOLLKAAL_01196 4.4e-244 G Bacterial extracellular solute-binding protein
IOLLKAAL_01197 0.0 uup S ABC transporter, ATP-binding protein
IOLLKAAL_01201 2.5e-259 qacA EGP Major facilitator Superfamily
IOLLKAAL_01202 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
IOLLKAAL_01203 4e-120 liaI S membrane
IOLLKAAL_01204 2.7e-79 XK27_02470 K LytTr DNA-binding domain
IOLLKAAL_01205 6.7e-50 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IOLLKAAL_01206 5.2e-104 yvdD 3.2.2.10 S Belongs to the LOG family
IOLLKAAL_01207 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOLLKAAL_01208 2e-41 L Helix-turn-helix domain
IOLLKAAL_01209 3.1e-102 L PFAM Integrase catalytic region
IOLLKAAL_01226 0.0 pepO 3.4.24.71 O Peptidase family M13
IOLLKAAL_01227 2.4e-262 glpK_1 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOLLKAAL_01228 3.8e-176 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
IOLLKAAL_01229 8.8e-153 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
IOLLKAAL_01230 2.2e-185 purR13 K Bacterial regulatory proteins, lacI family
IOLLKAAL_01231 1.9e-291 G isomerase
IOLLKAAL_01232 1.4e-261 G Protein of unknown function (DUF4038)
IOLLKAAL_01233 1.7e-151 licT K CAT RNA binding domain
IOLLKAAL_01234 0.0 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOLLKAAL_01235 2.7e-169 rbsR K helix_turn _helix lactose operon repressor
IOLLKAAL_01236 1.8e-170 uhpT EGP Major facilitator Superfamily
IOLLKAAL_01237 2.3e-308 2.7.7.7 S Domain of unknown function (DUF5060)
IOLLKAAL_01238 2.7e-117 drgA C nitroreductase
IOLLKAAL_01239 2.9e-170 C Oxidoreductase
IOLLKAAL_01240 4.3e-73 S SnoaL-like domain
IOLLKAAL_01241 2.8e-09 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
IOLLKAAL_01242 6.4e-90 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
IOLLKAAL_01243 2.4e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IOLLKAAL_01244 1.4e-08 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IOLLKAAL_01245 3.1e-47 qmcA O prohibitin homologues
IOLLKAAL_01246 5.8e-77 qmcA O prohibitin homologues
IOLLKAAL_01247 9.8e-185 P ABC transporter
IOLLKAAL_01248 3e-295 V ABC-type multidrug transport system, ATPase and permease components
IOLLKAAL_01249 2e-244 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOLLKAAL_01250 3.5e-211 yhjX P Major Facilitator Superfamily
IOLLKAAL_01251 1.3e-84 C nitroreductase
IOLLKAAL_01252 2.9e-48 V ABC transporter transmembrane region
IOLLKAAL_01253 1.3e-219 V ABC transporter transmembrane region
IOLLKAAL_01254 5.5e-53
IOLLKAAL_01255 2.1e-55
IOLLKAAL_01256 1.3e-76 K Acetyltransferase (GNAT) domain
IOLLKAAL_01257 6.3e-84 FG HIT domain
IOLLKAAL_01258 3.4e-46 S MazG-like family
IOLLKAAL_01259 7.7e-61
IOLLKAAL_01260 3e-118 3.1.3.48 T Tyrosine phosphatase family
IOLLKAAL_01261 5e-42
IOLLKAAL_01262 1.1e-245 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOLLKAAL_01263 2.4e-141 aroD S Serine hydrolase (FSH1)
IOLLKAAL_01264 6.4e-93 rimL J Acetyltransferase (GNAT) domain
IOLLKAAL_01265 4.4e-91 2.3.1.57 K Acetyltransferase (GNAT) family
IOLLKAAL_01266 4.9e-116 XK27_07525 3.6.1.55 F NUDIX domain
IOLLKAAL_01267 3.2e-141 S Alpha/beta hydrolase family
IOLLKAAL_01268 5.5e-113
IOLLKAAL_01269 1.9e-81
IOLLKAAL_01270 6.9e-92 S AAA domain
IOLLKAAL_01271 8.7e-153 2.7.1.89 M Phosphotransferase enzyme family
IOLLKAAL_01272 4.9e-84 3.6.1.55 F NUDIX domain
IOLLKAAL_01273 1.5e-149 2.4.2.3 F Phosphorylase superfamily
IOLLKAAL_01274 7.8e-151 2.4.2.3 F Phosphorylase superfamily
IOLLKAAL_01275 2.8e-84 6.3.3.2 S ASCH
IOLLKAAL_01276 3.5e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOLLKAAL_01277 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOLLKAAL_01278 2.1e-160 rbsU U ribose uptake protein RbsU
IOLLKAAL_01279 3.4e-157 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
IOLLKAAL_01280 5.5e-212 G Transmembrane secretion effector
IOLLKAAL_01281 5e-290 V ABC-type multidrug transport system, ATPase and permease components
IOLLKAAL_01282 1.6e-280 V ABC-type multidrug transport system, ATPase and permease components
IOLLKAAL_01283 8.8e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOLLKAAL_01284 2.7e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IOLLKAAL_01285 1.3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IOLLKAAL_01286 1.3e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
IOLLKAAL_01287 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IOLLKAAL_01288 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IOLLKAAL_01289 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IOLLKAAL_01290 6.3e-90 ypmB S Protein conserved in bacteria
IOLLKAAL_01291 6.4e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IOLLKAAL_01292 3.7e-114 dnaD L DnaD domain protein
IOLLKAAL_01293 1.1e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOLLKAAL_01294 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IOLLKAAL_01295 1.3e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOLLKAAL_01296 3.9e-104 ypsA S Belongs to the UPF0398 family
IOLLKAAL_01297 4.5e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOLLKAAL_01298 7.6e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IOLLKAAL_01299 6.1e-243 cpdA S Calcineurin-like phosphoesterase
IOLLKAAL_01300 7.6e-224 I transferase activity, transferring acyl groups other than amino-acyl groups
IOLLKAAL_01301 2e-174 degV S DegV family
IOLLKAAL_01302 3.2e-56
IOLLKAAL_01303 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IOLLKAAL_01304 2.9e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOLLKAAL_01305 2.1e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOLLKAAL_01306 1.3e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOLLKAAL_01307 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
IOLLKAAL_01308 0.0 FbpA K Fibronectin-binding protein
IOLLKAAL_01309 1.4e-63
IOLLKAAL_01310 1e-162 degV S EDD domain protein, DegV family
IOLLKAAL_01311 1e-151
IOLLKAAL_01312 1.4e-153 K Transcriptional regulator
IOLLKAAL_01313 8.3e-204 xerS L Belongs to the 'phage' integrase family
IOLLKAAL_01314 1.6e-123 yoaK S Protein of unknown function (DUF1275)
IOLLKAAL_01315 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOLLKAAL_01316 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IOLLKAAL_01317 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
IOLLKAAL_01318 2.4e-178 K Transcriptional regulator
IOLLKAAL_01319 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOLLKAAL_01320 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOLLKAAL_01321 7.5e-115 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOLLKAAL_01322 3.5e-106 lacA 2.3.1.79 S Transferase hexapeptide repeat
IOLLKAAL_01323 2.1e-165 akr5f 1.1.1.346 S reductase
IOLLKAAL_01324 4.8e-107 ybhL S Belongs to the BI1 family
IOLLKAAL_01325 3.7e-32
IOLLKAAL_01326 4.3e-169 4.1.1.45 S Amidohydrolase
IOLLKAAL_01327 6.3e-235 yrvN L AAA C-terminal domain
IOLLKAAL_01328 1.1e-19 K Transcriptional regulator
IOLLKAAL_01329 6.5e-156 C Aldo keto reductase
IOLLKAAL_01330 0.0 lmrA 3.6.3.44 V ABC transporter
IOLLKAAL_01331 2.6e-71 K helix_turn_helix multiple antibiotic resistance protein
IOLLKAAL_01332 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IOLLKAAL_01333 3.3e-76 yphH S Cupin domain
IOLLKAAL_01334 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOLLKAAL_01335 1.5e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IOLLKAAL_01337 6.9e-81 ywhK S Membrane
IOLLKAAL_01338 3.7e-156 UW LPXTG-motif cell wall anchor domain protein
IOLLKAAL_01339 4.4e-185 S AAA domain
IOLLKAAL_01340 3.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOLLKAAL_01341 9.9e-12
IOLLKAAL_01342 7e-40
IOLLKAAL_01343 7.7e-155 czcD P cation diffusion facilitator family transporter
IOLLKAAL_01344 4.2e-50 K Transcriptional regulator, ArsR family
IOLLKAAL_01345 1.1e-129 pgm3 G Belongs to the phosphoglycerate mutase family
IOLLKAAL_01346 1.1e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IOLLKAAL_01347 1.9e-150 1.6.5.2 GM NmrA-like family
IOLLKAAL_01348 1.6e-68 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
IOLLKAAL_01349 7e-292 V ABC-type multidrug transport system, ATPase and permease components
IOLLKAAL_01350 5.6e-229 P ABC transporter
IOLLKAAL_01352 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IOLLKAAL_01353 5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOLLKAAL_01354 5.1e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOLLKAAL_01355 7.4e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOLLKAAL_01356 1.7e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOLLKAAL_01357 1.5e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOLLKAAL_01358 3.7e-61 rplQ J Ribosomal protein L17
IOLLKAAL_01359 9.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOLLKAAL_01360 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOLLKAAL_01361 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOLLKAAL_01362 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IOLLKAAL_01363 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOLLKAAL_01364 4.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOLLKAAL_01365 4.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOLLKAAL_01366 1.3e-70 rplO J Binds to the 23S rRNA
IOLLKAAL_01367 1.4e-23 rpmD J Ribosomal protein L30
IOLLKAAL_01368 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOLLKAAL_01369 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOLLKAAL_01370 8.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOLLKAAL_01371 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOLLKAAL_01372 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOLLKAAL_01373 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOLLKAAL_01374 1.1e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOLLKAAL_01375 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOLLKAAL_01376 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOLLKAAL_01377 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IOLLKAAL_01378 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOLLKAAL_01379 7.2e-121 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOLLKAAL_01380 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOLLKAAL_01381 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOLLKAAL_01382 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOLLKAAL_01383 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOLLKAAL_01384 1e-105 rplD J Forms part of the polypeptide exit tunnel
IOLLKAAL_01385 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOLLKAAL_01386 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IOLLKAAL_01387 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOLLKAAL_01388 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOLLKAAL_01389 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOLLKAAL_01390 1.3e-106 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IOLLKAAL_01391 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOLLKAAL_01392 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOLLKAAL_01393 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOLLKAAL_01395 1.6e-08
IOLLKAAL_01396 2.1e-301 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IOLLKAAL_01397 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOLLKAAL_01398 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOLLKAAL_01399 0.0 S membrane
IOLLKAAL_01400 0.0 S membrane
IOLLKAAL_01401 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOLLKAAL_01402 1.1e-242 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOLLKAAL_01403 4.9e-60 yabR J S1 RNA binding domain
IOLLKAAL_01404 4e-60 divIC D Septum formation initiator
IOLLKAAL_01405 5.4e-34 yabO J S4 domain protein
IOLLKAAL_01406 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOLLKAAL_01407 1.9e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOLLKAAL_01408 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOLLKAAL_01409 2.3e-122 S (CBS) domain
IOLLKAAL_01410 2.5e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOLLKAAL_01411 5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOLLKAAL_01412 5.5e-267 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOLLKAAL_01413 7.2e-261 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOLLKAAL_01414 8e-41 rpmE2 J Ribosomal protein L31
IOLLKAAL_01415 4.6e-299 ybeC E amino acid
IOLLKAAL_01416 1.7e-134 XK27_08845 S ABC transporter, ATP-binding protein
IOLLKAAL_01417 6.4e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IOLLKAAL_01418 1.5e-178 ABC-SBP S ABC transporter
IOLLKAAL_01419 4.7e-227 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOLLKAAL_01420 2.4e-283 pipD E Dipeptidase
IOLLKAAL_01421 2.7e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IOLLKAAL_01422 9.8e-77 XK27_02070 S Nitroreductase family
IOLLKAAL_01423 1.1e-31 hxlR K Transcriptional regulator, HxlR family
IOLLKAAL_01424 2.1e-79
IOLLKAAL_01425 3.2e-66 S Putative adhesin
IOLLKAAL_01426 4.6e-39
IOLLKAAL_01427 1.2e-190 yfdV S Membrane transport protein
IOLLKAAL_01428 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IOLLKAAL_01429 4.1e-264 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IOLLKAAL_01430 6.8e-95
IOLLKAAL_01431 5.8e-56 K Transcriptional regulator
IOLLKAAL_01432 4.3e-86 XK27_09675 K Acetyltransferase (GNAT) domain
IOLLKAAL_01433 1.4e-63 S Protein of unknown function (DUF3021)
IOLLKAAL_01434 2.2e-73 K LytTr DNA-binding domain
IOLLKAAL_01435 1.4e-145 cylB V ABC-2 type transporter
IOLLKAAL_01436 1.7e-151 cylA V ABC transporter
IOLLKAAL_01439 3.4e-143 N Uncharacterized conserved protein (DUF2075)
IOLLKAAL_01440 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IOLLKAAL_01441 1.3e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOLLKAAL_01442 2.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOLLKAAL_01443 5.2e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
IOLLKAAL_01444 1.9e-112 yjbK S CYTH
IOLLKAAL_01445 3.7e-108 yjbH Q Thioredoxin
IOLLKAAL_01446 8.2e-165 coiA 3.6.4.12 S Competence protein
IOLLKAAL_01447 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IOLLKAAL_01448 5.2e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOLLKAAL_01449 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOLLKAAL_01450 4.2e-40 ptsH G phosphocarrier protein HPR
IOLLKAAL_01451 5.9e-25
IOLLKAAL_01452 0.0 clpE O Belongs to the ClpA ClpB family
IOLLKAAL_01453 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
IOLLKAAL_01454 5.1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IOLLKAAL_01455 3.6e-157 hlyX S Transporter associated domain
IOLLKAAL_01456 1.5e-77
IOLLKAAL_01457 1.8e-89
IOLLKAAL_01458 1.2e-111 ygaC J Belongs to the UPF0374 family
IOLLKAAL_01459 1.6e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
IOLLKAAL_01460 1e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOLLKAAL_01461 2.4e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IOLLKAAL_01462 5e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IOLLKAAL_01463 1.4e-217 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
IOLLKAAL_01464 1.9e-180 D Alpha beta
IOLLKAAL_01466 1.1e-152 S haloacid dehalogenase-like hydrolase
IOLLKAAL_01467 5.3e-204 EGP Major facilitator Superfamily
IOLLKAAL_01468 2.7e-260 glnA 6.3.1.2 E glutamine synthetase
IOLLKAAL_01469 1.8e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOLLKAAL_01470 8.1e-19 S Protein of unknown function (DUF3042)
IOLLKAAL_01471 5.1e-58 yqhL P Rhodanese-like protein
IOLLKAAL_01472 7.9e-35 yqgQ S Bacterial protein of unknown function (DUF910)
IOLLKAAL_01473 4e-119 gluP 3.4.21.105 S Rhomboid family
IOLLKAAL_01474 3.6e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOLLKAAL_01475 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOLLKAAL_01476 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IOLLKAAL_01477 0.0 S membrane
IOLLKAAL_01478 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOLLKAAL_01479 3.2e-203 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOLLKAAL_01480 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOLLKAAL_01481 2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOLLKAAL_01482 6.2e-63 yodB K Transcriptional regulator, HxlR family
IOLLKAAL_01483 2.8e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOLLKAAL_01484 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IOLLKAAL_01485 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOLLKAAL_01486 4.6e-280 arlS 2.7.13.3 T Histidine kinase
IOLLKAAL_01487 1.1e-130 K response regulator
IOLLKAAL_01488 4.2e-95 yceD S Uncharacterized ACR, COG1399
IOLLKAAL_01489 1.9e-217 ylbM S Belongs to the UPF0348 family
IOLLKAAL_01490 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOLLKAAL_01491 1.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IOLLKAAL_01492 1.7e-119 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOLLKAAL_01493 3.6e-210 yqeH S Ribosome biogenesis GTPase YqeH
IOLLKAAL_01494 2.4e-87 yqeG S HAD phosphatase, family IIIA
IOLLKAAL_01495 1.9e-189 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IOLLKAAL_01496 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOLLKAAL_01497 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IOLLKAAL_01498 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOLLKAAL_01499 8.6e-237 S CAAX protease self-immunity
IOLLKAAL_01500 1.6e-73 S Protein of unknown function (DUF3021)
IOLLKAAL_01501 1.1e-74 K LytTr DNA-binding domain
IOLLKAAL_01502 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOLLKAAL_01503 5.4e-156 dnaI L Primosomal protein DnaI
IOLLKAAL_01504 3.2e-237 dnaB L Replication initiation and membrane attachment
IOLLKAAL_01505 7.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOLLKAAL_01506 6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOLLKAAL_01507 5.7e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOLLKAAL_01508 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOLLKAAL_01509 9.2e-62 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOLLKAAL_01510 6.5e-120 K UTRA
IOLLKAAL_01511 4.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IOLLKAAL_01512 1.6e-85 cutC P Participates in the control of copper homeostasis
IOLLKAAL_01513 1.5e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOLLKAAL_01514 4.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IOLLKAAL_01515 1.1e-62
IOLLKAAL_01516 8.9e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOLLKAAL_01517 1e-221 ecsB U ABC transporter
IOLLKAAL_01518 9.7e-135 ecsA V ABC transporter, ATP-binding protein
IOLLKAAL_01519 3.5e-76 hit FG Scavenger mRNA decapping enzyme C-term binding
IOLLKAAL_01520 2e-51
IOLLKAAL_01521 9.5e-24 S YtxH-like protein
IOLLKAAL_01522 4.9e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOLLKAAL_01523 3e-184 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOLLKAAL_01524 0.0 L AAA domain
IOLLKAAL_01525 1.9e-220 yhaO L Ser Thr phosphatase family protein
IOLLKAAL_01526 9.5e-56 yheA S Belongs to the UPF0342 family
IOLLKAAL_01527 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IOLLKAAL_01528 9e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOLLKAAL_01530 0.0 GH23 S M26 IgA1-specific Metallo-endopeptidase C-terminal region
IOLLKAAL_01531 8e-45 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IOLLKAAL_01532 2.5e-245 G PTS system sugar-specific permease component
IOLLKAAL_01533 2.3e-78 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOLLKAAL_01534 3.1e-69 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOLLKAAL_01535 8.7e-116 manR K PRD domain
IOLLKAAL_01536 6.6e-96
IOLLKAAL_01537 7.9e-157 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IOLLKAAL_01538 4.6e-151 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
IOLLKAAL_01539 1.7e-198 V Beta-lactamase
IOLLKAAL_01541 1.8e-37 ung2 3.2.2.27 L Uracil-DNA glycosylase
IOLLKAAL_01542 8.1e-114 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IOLLKAAL_01543 1.1e-92 dps P Belongs to the Dps family
IOLLKAAL_01544 7.9e-35 copZ C Heavy-metal-associated domain
IOLLKAAL_01545 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
IOLLKAAL_01546 1.6e-108
IOLLKAAL_01547 1.5e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOLLKAAL_01548 2.1e-120 spaE S ABC-2 family transporter protein
IOLLKAAL_01549 2e-129 mutF V ABC transporter, ATP-binding protein
IOLLKAAL_01550 1.1e-243 nhaC C Na H antiporter NhaC
IOLLKAAL_01551 7.6e-160 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
IOLLKAAL_01552 1.9e-95 S UPF0397 protein
IOLLKAAL_01553 0.0 ykoD P ABC transporter, ATP-binding protein
IOLLKAAL_01554 4.1e-142 cbiQ P cobalt transport
IOLLKAAL_01555 2.1e-118 ybhL S Belongs to the BI1 family
IOLLKAAL_01556 0.0 GT2,GT4 M family 8
IOLLKAAL_01557 0.0 GT2,GT4 M family 8
IOLLKAAL_01558 4.5e-227 M Pfam:DUF1792
IOLLKAAL_01559 2.9e-75 M lipopolysaccharide 3-alpha-galactosyltransferase activity
IOLLKAAL_01560 0.0 UW Tetratricopeptide repeat
IOLLKAAL_01561 3.8e-148 S hydrolase
IOLLKAAL_01562 6.6e-251 L transposase, IS605 OrfB family
IOLLKAAL_01563 5.7e-85 tlpA2 L Transposase IS200 like
IOLLKAAL_01564 6.9e-167 yegS 2.7.1.107 G Lipid kinase
IOLLKAAL_01565 6e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOLLKAAL_01566 5.2e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOLLKAAL_01567 3.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOLLKAAL_01568 1.9e-206 camS S sex pheromone
IOLLKAAL_01569 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOLLKAAL_01570 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IOLLKAAL_01571 2.3e-113 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
IOLLKAAL_01572 6.2e-103 S ECF transporter, substrate-specific component
IOLLKAAL_01574 1.8e-83 ydcK S Belongs to the SprT family
IOLLKAAL_01575 1.2e-131 M Glycosyltransferase sugar-binding region containing DXD motif
IOLLKAAL_01576 1.1e-256 epsU S Polysaccharide biosynthesis protein
IOLLKAAL_01577 3.4e-227 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOLLKAAL_01578 2.8e-135
IOLLKAAL_01579 1.5e-286 V ABC transporter transmembrane region
IOLLKAAL_01580 0.0 pacL 3.6.3.8 P P-type ATPase
IOLLKAAL_01581 0.0 spoVK O ATPase family associated with various cellular activities (AAA)
IOLLKAAL_01582 5.5e-155 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOLLKAAL_01583 3.2e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOLLKAAL_01584 0.0 S Glycosyltransferase like family 2
IOLLKAAL_01585 4.9e-207 csaB M Glycosyl transferases group 1
IOLLKAAL_01586 1.6e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOLLKAAL_01587 7.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IOLLKAAL_01588 3.6e-123 gntR1 K UTRA
IOLLKAAL_01589 2.7e-189
IOLLKAAL_01590 1.9e-52 P Rhodanese Homology Domain
IOLLKAAL_01593 9.9e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
IOLLKAAL_01594 1.9e-36 K SIS domain
IOLLKAAL_01595 2.5e-31 yjgN S Bacterial protein of unknown function (DUF898)
IOLLKAAL_01597 3.1e-97 M LysM domain protein
IOLLKAAL_01598 3.5e-114 M LysM domain protein
IOLLKAAL_01599 3.9e-133 S Putative ABC-transporter type IV
IOLLKAAL_01600 1.5e-60 psiE S Phosphate-starvation-inducible E
IOLLKAAL_01601 2.9e-93 K acetyltransferase
IOLLKAAL_01603 2.3e-164 yvgN C Aldo keto reductase
IOLLKAAL_01604 2.3e-248 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IOLLKAAL_01605 3.8e-70 S Uncharacterized protein conserved in bacteria (DUF2263)
IOLLKAAL_01606 3.7e-174 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOLLKAAL_01607 0.0 lhr L DEAD DEAH box helicase
IOLLKAAL_01608 3.2e-253 P P-loop Domain of unknown function (DUF2791)
IOLLKAAL_01609 0.0 S TerB-C domain
IOLLKAAL_01610 4.1e-37 4.1.1.44 S decarboxylase
IOLLKAAL_01611 9.6e-81 4.1.1.44 S decarboxylase
IOLLKAAL_01612 1.5e-71
IOLLKAAL_01613 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IOLLKAAL_01614 1.2e-244 cycA E Amino acid permease
IOLLKAAL_01615 5.2e-81 usp6 T universal stress protein
IOLLKAAL_01617 3.6e-238 rarA L recombination factor protein RarA
IOLLKAAL_01618 2.4e-83 yueI S Protein of unknown function (DUF1694)
IOLLKAAL_01619 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOLLKAAL_01621 2.1e-289 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOLLKAAL_01622 4.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
IOLLKAAL_01623 1.1e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOLLKAAL_01624 2.5e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOLLKAAL_01625 2.1e-178 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IOLLKAAL_01626 0.0 3.6.3.8 P P-type ATPase
IOLLKAAL_01627 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOLLKAAL_01628 7.4e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOLLKAAL_01629 6.4e-125 S Haloacid dehalogenase-like hydrolase
IOLLKAAL_01630 6.1e-111 radC L DNA repair protein
IOLLKAAL_01631 2.7e-164 mreB D cell shape determining protein MreB
IOLLKAAL_01632 6.1e-141 mreC M Involved in formation and maintenance of cell shape
IOLLKAAL_01633 1.6e-94 mreD
IOLLKAAL_01634 3.6e-13 S Protein of unknown function (DUF4044)
IOLLKAAL_01635 2.7e-52 S Protein of unknown function (DUF3397)
IOLLKAAL_01636 4.1e-77 mraZ K Belongs to the MraZ family
IOLLKAAL_01637 1.7e-179 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOLLKAAL_01638 4.8e-55 ftsL D Cell division protein FtsL
IOLLKAAL_01639 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IOLLKAAL_01640 1.2e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOLLKAAL_01641 3.6e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOLLKAAL_01642 1.5e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOLLKAAL_01643 2e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOLLKAAL_01644 6e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOLLKAAL_01645 1.1e-243 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOLLKAAL_01646 1.3e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOLLKAAL_01647 1.2e-27 yggT S YGGT family
IOLLKAAL_01648 2.4e-147 ylmH S S4 domain protein
IOLLKAAL_01649 3.2e-120 gpsB D DivIVA domain protein
IOLLKAAL_01650 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOLLKAAL_01651 2.3e-33 cspA K 'Cold-shock' DNA-binding domain
IOLLKAAL_01652 1.7e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IOLLKAAL_01653 4.9e-34
IOLLKAAL_01654 1.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOLLKAAL_01655 3.5e-216 iscS 2.8.1.7 E Aminotransferase class V
IOLLKAAL_01656 9.6e-58 XK27_04120 S Putative amino acid metabolism
IOLLKAAL_01657 8.7e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOLLKAAL_01658 3.1e-124 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IOLLKAAL_01659 1e-116 S Repeat protein
IOLLKAAL_01660 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOLLKAAL_01661 2.6e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IOLLKAAL_01662 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOLLKAAL_01663 2.3e-34 ykzG S Belongs to the UPF0356 family
IOLLKAAL_01664 5.2e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOLLKAAL_01665 0.0 typA T GTP-binding protein TypA
IOLLKAAL_01666 7.7e-211 ftsW D Belongs to the SEDS family
IOLLKAAL_01667 7.4e-50 ylbG S UPF0298 protein
IOLLKAAL_01668 2.1e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IOLLKAAL_01669 9.6e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOLLKAAL_01670 1.5e-183 ylbL T Belongs to the peptidase S16 family
IOLLKAAL_01671 8.8e-82 comEA L Competence protein ComEA
IOLLKAAL_01672 0.0 comEC S Competence protein ComEC
IOLLKAAL_01673 1.5e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
IOLLKAAL_01674 4.4e-34 rpsT J Binds directly to 16S ribosomal RNA
IOLLKAAL_01675 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOLLKAAL_01676 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOLLKAAL_01677 7.2e-158
IOLLKAAL_01678 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOLLKAAL_01679 4e-203 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOLLKAAL_01680 2.1e-230 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOLLKAAL_01681 1.7e-102 engB D Necessary for normal cell division and for the maintenance of normal septation
IOLLKAAL_01682 2.2e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOLLKAAL_01683 5.1e-82
IOLLKAAL_01685 1.7e-114 frnE Q DSBA-like thioredoxin domain
IOLLKAAL_01686 6e-78 S Domain of unknown function (DUF4767)
IOLLKAAL_01687 9.2e-218
IOLLKAAL_01688 2.5e-121 frnE Q DSBA-like thioredoxin domain
IOLLKAAL_01689 1.9e-163
IOLLKAAL_01690 6.4e-79 K DNA-templated transcription, initiation
IOLLKAAL_01691 4.6e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOLLKAAL_01692 3.7e-138 epsB M biosynthesis protein
IOLLKAAL_01693 8.7e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IOLLKAAL_01694 2.6e-138 ywqE 3.1.3.48 GM PHP domain protein
IOLLKAAL_01695 5.1e-82 rfbP 2.7.8.6 M Bacterial sugar transferase
IOLLKAAL_01696 5.8e-138 cps1D M Domain of unknown function (DUF4422)
IOLLKAAL_01697 1.3e-124 waaB GT4 M Glycosyl transferases group 1
IOLLKAAL_01698 4e-40 S O-antigen ligase like membrane protein
IOLLKAAL_01699 5.5e-53 M Glycosyltransferase like family 2
IOLLKAAL_01700 8.2e-50 G Protein of unknown function (DUF563)
IOLLKAAL_01701 5.5e-65 S Glycosyltransferase like family 2
IOLLKAAL_01702 3.8e-102 M transferase activity, transferring glycosyl groups
IOLLKAAL_01703 6.2e-45 H Core-2/I-Branching enzyme
IOLLKAAL_01704 3.3e-211 glf 5.4.99.9 M UDP-galactopyranose mutase
IOLLKAAL_01705 1.9e-251 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
IOLLKAAL_01706 2.6e-91 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IOLLKAAL_01707 1.4e-223 rodA D Belongs to the SEDS family
IOLLKAAL_01708 6.6e-34 S Protein of unknown function (DUF2969)
IOLLKAAL_01709 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IOLLKAAL_01710 6.8e-13 S DNA-directed RNA polymerase subunit beta
IOLLKAAL_01711 1.7e-179 mbl D Cell shape determining protein MreB Mrl
IOLLKAAL_01712 2.4e-31 ywzB S Protein of unknown function (DUF1146)
IOLLKAAL_01713 2.4e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IOLLKAAL_01714 9.6e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOLLKAAL_01715 1.6e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOLLKAAL_01716 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOLLKAAL_01717 9.8e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOLLKAAL_01718 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOLLKAAL_01719 4.7e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOLLKAAL_01720 5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
IOLLKAAL_01721 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOLLKAAL_01722 2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOLLKAAL_01723 7.1e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOLLKAAL_01724 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOLLKAAL_01725 5.5e-112 tdk 2.7.1.21 F thymidine kinase
IOLLKAAL_01726 5.5e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
IOLLKAAL_01727 1.1e-194 ampC V Beta-lactamase
IOLLKAAL_01730 3.2e-69
IOLLKAAL_01731 2.2e-233 EGP Major facilitator Superfamily
IOLLKAAL_01732 1.9e-261 pgi 5.3.1.9 G Belongs to the GPI family
IOLLKAAL_01733 2.2e-105 vanZ V VanZ like family
IOLLKAAL_01734 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOLLKAAL_01735 2.6e-269 T PhoQ Sensor
IOLLKAAL_01736 2.2e-128 K Transcriptional regulatory protein, C terminal
IOLLKAAL_01737 6e-67 S SdpI/YhfL protein family
IOLLKAAL_01738 5e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
IOLLKAAL_01739 4.6e-61 patB 4.4.1.8 E Aminotransferase, class I
IOLLKAAL_01740 1.5e-42 S Phage Mu protein F like protein
IOLLKAAL_01741 5.4e-235 S Phage portal protein, SPP1 Gp6-like
IOLLKAAL_01742 2.4e-242 S Phage terminase, large subunit
IOLLKAAL_01743 2.5e-64 xtmA L Terminase small subunit
IOLLKAAL_01744 4e-29
IOLLKAAL_01748 1.9e-86
IOLLKAAL_01749 9.8e-19
IOLLKAAL_01750 8.6e-23
IOLLKAAL_01751 3.1e-17
IOLLKAAL_01753 7.6e-42
IOLLKAAL_01754 6.8e-62 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
IOLLKAAL_01760 1.4e-25
IOLLKAAL_01761 2.4e-133 S DNA binding
IOLLKAAL_01764 2.4e-18 K Transcriptional regulator
IOLLKAAL_01765 5.1e-67 L Helix-turn-helix domain
IOLLKAAL_01766 8e-44 S ERF superfamily
IOLLKAAL_01768 7.5e-39
IOLLKAAL_01769 2.9e-15
IOLLKAAL_01771 1.9e-58 S Domain of unknown function (DUF771)
IOLLKAAL_01772 2.5e-09 K Helix-turn-helix XRE-family like proteins
IOLLKAAL_01773 5.1e-57 S protein disulfide oxidoreductase activity
IOLLKAAL_01774 1.8e-83 S Pfam:Peptidase_M78
IOLLKAAL_01775 1.3e-27 S Bacterial PH domain
IOLLKAAL_01777 2.1e-149 L Belongs to the 'phage' integrase family
IOLLKAAL_01779 1e-226 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOLLKAAL_01780 4.3e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
IOLLKAAL_01781 4e-84 comGF U Putative Competence protein ComGF
IOLLKAAL_01782 7.5e-11
IOLLKAAL_01783 4.1e-58
IOLLKAAL_01784 1.2e-40 comGC U Required for transformation and DNA binding
IOLLKAAL_01785 9.9e-175 comGB NU type II secretion system
IOLLKAAL_01786 1.5e-180 comGA NU Type II IV secretion system protein
IOLLKAAL_01787 1.5e-132 yebC K Transcriptional regulatory protein
IOLLKAAL_01788 4.7e-96 S VanZ like family
IOLLKAAL_01789 1.8e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOLLKAAL_01790 7e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
IOLLKAAL_01791 8e-148 yisY 1.11.1.10 S Alpha/beta hydrolase family
IOLLKAAL_01792 1.6e-115
IOLLKAAL_01793 7e-199 S Putative adhesin
IOLLKAAL_01794 4.5e-61 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOLLKAAL_01795 7.7e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOLLKAAL_01796 2.4e-147 S Sucrose-6F-phosphate phosphohydrolase
IOLLKAAL_01797 4.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOLLKAAL_01798 2.9e-171 ybbR S YbbR-like protein
IOLLKAAL_01799 2.9e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOLLKAAL_01800 5.9e-210 potD P ABC transporter
IOLLKAAL_01801 8.5e-137 potC P ABC transporter permease
IOLLKAAL_01802 1e-129 potB P ABC transporter permease
IOLLKAAL_01803 3.8e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOLLKAAL_01804 7.6e-166 murB 1.3.1.98 M Cell wall formation
IOLLKAAL_01805 6.8e-98 dnaQ 2.7.7.7 L DNA polymerase III
IOLLKAAL_01806 2.5e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IOLLKAAL_01807 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IOLLKAAL_01808 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOLLKAAL_01809 1.1e-153 ycsE S Sucrose-6F-phosphate phosphohydrolase
IOLLKAAL_01810 1.3e-93
IOLLKAAL_01811 1.3e-75

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)