ORF_ID e_value Gene_name EC_number CAZy COGs Description
MLCNMKMC_00001 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLCNMKMC_00002 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLCNMKMC_00003 1.8e-37 yaaB S Domain of unknown function (DUF370)
MLCNMKMC_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLCNMKMC_00005 2.4e-33 yaaA S S4 domain
MLCNMKMC_00006 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLCNMKMC_00007 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLCNMKMC_00008 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLCNMKMC_00009 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLCNMKMC_00010 4.2e-107 jag S single-stranded nucleic acid binding R3H
MLCNMKMC_00011 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLCNMKMC_00012 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLCNMKMC_00013 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MLCNMKMC_00014 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MLCNMKMC_00015 1.6e-73 S Bacterial PH domain
MLCNMKMC_00016 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MLCNMKMC_00017 2.1e-149 spo0J K Belongs to the ParB family
MLCNMKMC_00018 1.6e-111 yyaC S Sporulation protein YyaC
MLCNMKMC_00019 1.4e-176 yyaD S Membrane
MLCNMKMC_00020 2.3e-33 yyzM S protein conserved in bacteria
MLCNMKMC_00021 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLCNMKMC_00022 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLCNMKMC_00023 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
MLCNMKMC_00024 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLCNMKMC_00025 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLCNMKMC_00026 3.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
MLCNMKMC_00027 2.1e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MLCNMKMC_00028 2.2e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLCNMKMC_00029 1.8e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MLCNMKMC_00030 6.1e-244 EGP Major facilitator superfamily
MLCNMKMC_00031 2e-166 yyaK S CAAX protease self-immunity
MLCNMKMC_00032 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MLCNMKMC_00033 6.2e-244 tetL EGP Major facilitator Superfamily
MLCNMKMC_00034 7.2e-106 yyaP 1.5.1.3 H RibD C-terminal domain
MLCNMKMC_00035 3.5e-66 yyaQ S YjbR
MLCNMKMC_00036 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
MLCNMKMC_00037 1.5e-101 yyaS S Membrane
MLCNMKMC_00038 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
MLCNMKMC_00039 5.6e-77 yybA 2.3.1.57 K transcriptional
MLCNMKMC_00040 3e-127 S Metallo-beta-lactamase superfamily
MLCNMKMC_00041 2.7e-77 yybC
MLCNMKMC_00042 2e-79 yjcF S Acetyltransferase (GNAT) domain
MLCNMKMC_00043 2.1e-165 yybE K Transcriptional regulator
MLCNMKMC_00044 2.8e-216 ynfM EGP Major facilitator Superfamily
MLCNMKMC_00045 1.4e-118 yybG S Pentapeptide repeat-containing protein
MLCNMKMC_00046 5.5e-65 yybH S SnoaL-like domain
MLCNMKMC_00047 4.9e-129
MLCNMKMC_00048 2.6e-115 V ATPases associated with a variety of cellular activities
MLCNMKMC_00049 2e-127 S Protein of unknown function (DUF2705)
MLCNMKMC_00050 9e-122
MLCNMKMC_00051 4.1e-125
MLCNMKMC_00052 1.3e-78 yybN S Protein of unknown function (DUF2712)
MLCNMKMC_00053 1e-16
MLCNMKMC_00054 3.9e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MLCNMKMC_00056 1.5e-58
MLCNMKMC_00057 8.1e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MLCNMKMC_00058 1.7e-66 ydeP3 K Transcriptional regulator
MLCNMKMC_00059 3.3e-83 cotF M Spore coat protein
MLCNMKMC_00061 8.3e-160 yybS S membrane
MLCNMKMC_00062 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MLCNMKMC_00063 2.2e-73 rplI J binds to the 23S rRNA
MLCNMKMC_00064 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLCNMKMC_00065 7.1e-220 yeaN P COG2807 Cyanate permease
MLCNMKMC_00066 1.9e-15 yycC K YycC-like protein
MLCNMKMC_00068 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MLCNMKMC_00069 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MLCNMKMC_00070 2e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLCNMKMC_00071 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLCNMKMC_00076 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_00077 0.0 vicK 2.7.13.3 T Histidine kinase
MLCNMKMC_00078 1.2e-258 yycH S protein conserved in bacteria
MLCNMKMC_00079 1.8e-153 yycI S protein conserved in bacteria
MLCNMKMC_00080 1.3e-148 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MLCNMKMC_00081 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLCNMKMC_00082 1.7e-34 S Peptidase propeptide and YPEB domain
MLCNMKMC_00083 1.2e-73 S Peptidase propeptide and YPEB domain
MLCNMKMC_00084 1.5e-94 K PFAM response regulator receiver
MLCNMKMC_00085 7.9e-173 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLCNMKMC_00086 9.9e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MLCNMKMC_00088 4.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MLCNMKMC_00089 9.7e-261 rocE E amino acid
MLCNMKMC_00090 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MLCNMKMC_00092 5e-188 S aspartate phosphatase
MLCNMKMC_00093 3.4e-85 yycN 2.3.1.128 K Acetyltransferase
MLCNMKMC_00094 2.9e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLCNMKMC_00095 5.3e-204 yycP
MLCNMKMC_00096 1.7e-30 yycQ S Protein of unknown function (DUF2651)
MLCNMKMC_00098 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLCNMKMC_00099 4.2e-71
MLCNMKMC_00100 1.1e-09 S YyzF-like protein
MLCNMKMC_00101 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLCNMKMC_00102 7.3e-280 S Calcineurin-like phosphoesterase
MLCNMKMC_00103 3.5e-65
MLCNMKMC_00104 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
MLCNMKMC_00105 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MLCNMKMC_00106 2.7e-109 prrC P ABC transporter
MLCNMKMC_00107 3.3e-119 S ABC-2 family transporter protein
MLCNMKMC_00108 7.1e-11
MLCNMKMC_00109 3e-125 yydK K Transcriptional regulator
MLCNMKMC_00110 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MLCNMKMC_00111 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLCNMKMC_00112 1.9e-286 ahpF O Alkyl hydroperoxide reductase
MLCNMKMC_00113 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MLCNMKMC_00114 1.8e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLCNMKMC_00115 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
MLCNMKMC_00116 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MLCNMKMC_00117 2.8e-126 gntR K transcriptional
MLCNMKMC_00118 6.6e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MLCNMKMC_00119 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
MLCNMKMC_00120 1.4e-116 yxaC M effector of murein hydrolase
MLCNMKMC_00121 5.2e-50 S LrgA family
MLCNMKMC_00122 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_00123 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_00124 1.2e-100 yxaF K Transcriptional regulator
MLCNMKMC_00125 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
MLCNMKMC_00126 1.4e-228 P Protein of unknown function (DUF418)
MLCNMKMC_00127 1.1e-75 yxaI S membrane protein domain
MLCNMKMC_00128 3.5e-65 S Family of unknown function (DUF5391)
MLCNMKMC_00129 6.8e-93 S PQQ-like domain
MLCNMKMC_00130 7.6e-214 yxaM U MFS_1 like family
MLCNMKMC_00131 0.0 asnB 6.3.5.4 E Asparagine synthase
MLCNMKMC_00132 1.1e-86 yxnB
MLCNMKMC_00133 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
MLCNMKMC_00134 3.3e-127 yxbB Q Met-10+ like-protein
MLCNMKMC_00135 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
MLCNMKMC_00136 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
MLCNMKMC_00137 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLCNMKMC_00138 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
MLCNMKMC_00139 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
MLCNMKMC_00141 0.0 htpG O Molecular chaperone. Has ATPase activity
MLCNMKMC_00142 2.3e-246 csbC EGP Major facilitator Superfamily
MLCNMKMC_00143 8.3e-48 yxcD S Protein of unknown function (DUF2653)
MLCNMKMC_00145 8.3e-176 iolS C Aldo keto reductase
MLCNMKMC_00146 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MLCNMKMC_00147 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLCNMKMC_00148 3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MLCNMKMC_00149 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MLCNMKMC_00150 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MLCNMKMC_00151 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MLCNMKMC_00152 1.3e-235 iolF EGP Major facilitator Superfamily
MLCNMKMC_00153 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MLCNMKMC_00154 8.6e-167 iolH G Xylose isomerase-like TIM barrel
MLCNMKMC_00155 1.2e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MLCNMKMC_00156 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MLCNMKMC_00157 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_00158 1.3e-182 T PhoQ Sensor
MLCNMKMC_00159 9.4e-141 yxdL V ABC transporter, ATP-binding protein
MLCNMKMC_00160 0.0 yxdM V ABC transporter (permease)
MLCNMKMC_00161 1.5e-58 yxeA S Protein of unknown function (DUF1093)
MLCNMKMC_00162 6e-177 fhuD P ABC transporter
MLCNMKMC_00163 8.5e-69
MLCNMKMC_00165 1.3e-20 yxeE
MLCNMKMC_00168 1.7e-148 yidA S hydrolases of the HAD superfamily
MLCNMKMC_00169 7.2e-186 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MLCNMKMC_00170 1.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLCNMKMC_00171 4.7e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLCNMKMC_00172 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MLCNMKMC_00173 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
MLCNMKMC_00174 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MLCNMKMC_00175 1.4e-212 yxeP 3.5.1.47 E hydrolase activity
MLCNMKMC_00176 1.9e-250 yxeQ S MmgE/PrpD family
MLCNMKMC_00177 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
MLCNMKMC_00178 3e-153 yxxB S Domain of Unknown Function (DUF1206)
MLCNMKMC_00179 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLCNMKMC_00180 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLCNMKMC_00181 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLCNMKMC_00182 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MLCNMKMC_00183 3.4e-250 lysP E amino acid
MLCNMKMC_00184 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MLCNMKMC_00185 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MLCNMKMC_00186 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLCNMKMC_00187 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
MLCNMKMC_00188 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MLCNMKMC_00189 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MLCNMKMC_00190 2.1e-21 S Domain of unknown function (DUF5082)
MLCNMKMC_00191 3.6e-39 yxiC S Family of unknown function (DUF5344)
MLCNMKMC_00192 0.0 S nuclease activity
MLCNMKMC_00193 2.2e-78 S SMI1 / KNR4 family
MLCNMKMC_00194 3.6e-51
MLCNMKMC_00195 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLCNMKMC_00196 1.1e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLCNMKMC_00197 1.1e-72 yxiE T Belongs to the universal stress protein A family
MLCNMKMC_00198 2.9e-168 yxxF EG EamA-like transporter family
MLCNMKMC_00199 0.0 wapA M COG3209 Rhs family protein
MLCNMKMC_00200 1.5e-71 yxxG
MLCNMKMC_00201 1.7e-84
MLCNMKMC_00202 6.4e-63
MLCNMKMC_00203 3.7e-75 yxiG
MLCNMKMC_00204 4.9e-46
MLCNMKMC_00205 3.8e-81
MLCNMKMC_00206 1.6e-93 yxiI S Protein of unknown function (DUF2716)
MLCNMKMC_00207 1e-47 yxiJ S YxiJ-like protein
MLCNMKMC_00210 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MLCNMKMC_00211 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MLCNMKMC_00212 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
MLCNMKMC_00213 2e-110
MLCNMKMC_00214 8.3e-151 licT K transcriptional antiterminator
MLCNMKMC_00215 3.3e-143 exoK GH16 M licheninase activity
MLCNMKMC_00216 6.6e-224 citH C Citrate transporter
MLCNMKMC_00217 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MLCNMKMC_00218 2.7e-48 yxiS
MLCNMKMC_00219 1.2e-22 T Domain of unknown function (DUF4163)
MLCNMKMC_00220 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLCNMKMC_00221 3.1e-161 rlmA 2.1.1.187 Q Methyltransferase domain
MLCNMKMC_00222 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
MLCNMKMC_00223 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLCNMKMC_00224 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLCNMKMC_00225 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLCNMKMC_00226 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
MLCNMKMC_00227 6.7e-220 yxjG 2.1.1.14 E Methionine synthase
MLCNMKMC_00228 1.3e-84 yxjI S LURP-one-related
MLCNMKMC_00231 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MLCNMKMC_00232 7.8e-112 K helix_turn_helix, Lux Regulon
MLCNMKMC_00233 8.3e-192 yxjM T Signal transduction histidine kinase
MLCNMKMC_00234 3.1e-78 S Protein of unknown function (DUF1453)
MLCNMKMC_00235 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MLCNMKMC_00236 1.4e-73 yxkC S Domain of unknown function (DUF4352)
MLCNMKMC_00237 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLCNMKMC_00238 7.9e-274 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLCNMKMC_00239 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
MLCNMKMC_00240 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MLCNMKMC_00241 6.2e-154 yxkH G Polysaccharide deacetylase
MLCNMKMC_00243 0.0 3.4.24.84 O Peptidase family M48
MLCNMKMC_00244 1.5e-229 cimH C COG3493 Na citrate symporter
MLCNMKMC_00245 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
MLCNMKMC_00246 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MLCNMKMC_00247 0.0 cydD V ATP-binding
MLCNMKMC_00248 0.0 cydD V ATP-binding protein
MLCNMKMC_00249 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLCNMKMC_00250 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MLCNMKMC_00251 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_00252 3.9e-48 yxlC S Family of unknown function (DUF5345)
MLCNMKMC_00253 1.2e-31
MLCNMKMC_00254 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MLCNMKMC_00255 5.1e-167 yxlF V ABC transporter, ATP-binding protein
MLCNMKMC_00256 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLCNMKMC_00257 5.3e-215 yxlH EGP Major facilitator Superfamily
MLCNMKMC_00258 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MLCNMKMC_00259 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MLCNMKMC_00260 1.1e-19 yxzF
MLCNMKMC_00261 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MLCNMKMC_00262 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MLCNMKMC_00263 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLCNMKMC_00264 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLCNMKMC_00265 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLCNMKMC_00266 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MLCNMKMC_00267 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_00268 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLCNMKMC_00269 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_00270 1.2e-232 dltB M membrane protein involved in D-alanine export
MLCNMKMC_00271 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_00272 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MLCNMKMC_00273 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MLCNMKMC_00274 1e-130 ynfM EGP Major facilitator Superfamily
MLCNMKMC_00275 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
MLCNMKMC_00276 8.1e-93 K Helix-turn-helix XRE-family like proteins
MLCNMKMC_00277 9.8e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MLCNMKMC_00278 1.2e-230 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLCNMKMC_00279 2.3e-87 ywaE K Transcriptional regulator
MLCNMKMC_00280 8.2e-123 ywaF S Integral membrane protein
MLCNMKMC_00281 2.9e-167 gspA M General stress
MLCNMKMC_00282 6e-149 sacY K transcriptional antiterminator
MLCNMKMC_00283 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLCNMKMC_00284 3.1e-273 epr 3.4.21.62 O Belongs to the peptidase S8 family
MLCNMKMC_00285 4.6e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLCNMKMC_00286 4.8e-117 ywbB S Protein of unknown function (DUF2711)
MLCNMKMC_00287 9.9e-67 ywbC 4.4.1.5 E glyoxalase
MLCNMKMC_00288 1e-218 ywbD 2.1.1.191 J Methyltransferase
MLCNMKMC_00289 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MLCNMKMC_00290 2.4e-207 ywbF EGP Major facilitator Superfamily
MLCNMKMC_00291 2.3e-111 ywbG M effector of murein hydrolase
MLCNMKMC_00292 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MLCNMKMC_00293 1.6e-152 ywbI K Transcriptional regulator
MLCNMKMC_00294 3.4e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLCNMKMC_00295 1.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLCNMKMC_00296 6.7e-249 P COG0672 High-affinity Fe2 Pb2 permease
MLCNMKMC_00297 4.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
MLCNMKMC_00298 4.9e-224 ywbN P Dyp-type peroxidase family protein
MLCNMKMC_00299 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MLCNMKMC_00300 4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLCNMKMC_00301 2.9e-48 ywcB S Protein of unknown function, DUF485
MLCNMKMC_00303 1.1e-121 ywcC K transcriptional regulator
MLCNMKMC_00304 9.5e-60 gtcA S GtrA-like protein
MLCNMKMC_00305 1.4e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLCNMKMC_00306 1.6e-304 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MLCNMKMC_00307 1e-35 ywzA S membrane
MLCNMKMC_00308 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MLCNMKMC_00309 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLCNMKMC_00310 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MLCNMKMC_00311 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MLCNMKMC_00312 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MLCNMKMC_00313 4e-204 S Acetyltransferase
MLCNMKMC_00314 2.9e-202 rodA D Belongs to the SEDS family
MLCNMKMC_00315 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MLCNMKMC_00316 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLCNMKMC_00317 0.0 vpr O Belongs to the peptidase S8 family
MLCNMKMC_00319 5.9e-149 sacT K transcriptional antiterminator
MLCNMKMC_00320 6.7e-139 focA P Formate/nitrite transporter
MLCNMKMC_00321 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLCNMKMC_00322 4.4e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MLCNMKMC_00323 2e-28 ywdA
MLCNMKMC_00324 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLCNMKMC_00325 1.3e-57 pex K Transcriptional regulator PadR-like family
MLCNMKMC_00326 9.5e-62 ywdD
MLCNMKMC_00327 8.3e-41 ywdD
MLCNMKMC_00329 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
MLCNMKMC_00330 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLCNMKMC_00331 9.1e-71 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLCNMKMC_00332 3.1e-165 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLCNMKMC_00333 5e-48 ywdI S Family of unknown function (DUF5327)
MLCNMKMC_00334 3.7e-238 ywdJ F Xanthine uracil
MLCNMKMC_00335 4.3e-59 ywdK S small membrane protein
MLCNMKMC_00336 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MLCNMKMC_00337 9.1e-144 spsA M Spore Coat
MLCNMKMC_00338 3.3e-269 spsB M Capsule polysaccharide biosynthesis protein
MLCNMKMC_00339 1.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
MLCNMKMC_00340 4.4e-163 spsD 2.3.1.210 K Spore Coat
MLCNMKMC_00341 7.1e-214 spsE 2.5.1.56 M acid synthase
MLCNMKMC_00342 1.8e-130 spsF M Spore Coat
MLCNMKMC_00343 1.4e-187 spsG M Spore Coat
MLCNMKMC_00344 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLCNMKMC_00345 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLCNMKMC_00346 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLCNMKMC_00347 1.3e-86 spsL 5.1.3.13 M Spore Coat
MLCNMKMC_00348 1.2e-77
MLCNMKMC_00349 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLCNMKMC_00350 3.9e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLCNMKMC_00351 0.0 rocB E arginine degradation protein
MLCNMKMC_00352 4.8e-260 lysP E amino acid
MLCNMKMC_00353 3e-205 ywfA EGP Major facilitator Superfamily
MLCNMKMC_00354 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MLCNMKMC_00355 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MLCNMKMC_00356 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_00357 6.1e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MLCNMKMC_00358 5.6e-209 bacE EGP Major facilitator Superfamily
MLCNMKMC_00359 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
MLCNMKMC_00360 7.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
MLCNMKMC_00361 1.1e-146 ywfI C May function as heme-dependent peroxidase
MLCNMKMC_00362 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MLCNMKMC_00363 1.1e-156 cysL K Transcriptional regulator
MLCNMKMC_00364 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MLCNMKMC_00365 5.7e-158 ywfM EG EamA-like transporter family
MLCNMKMC_00366 1e-110 rsfA_1
MLCNMKMC_00367 3.1e-36 ywzC S Belongs to the UPF0741 family
MLCNMKMC_00368 1.9e-255 ywfO S COG1078 HD superfamily phosphohydrolases
MLCNMKMC_00369 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MLCNMKMC_00370 7.6e-77 yffB K Transcriptional regulator
MLCNMKMC_00371 2e-237 mmr U Major Facilitator Superfamily
MLCNMKMC_00373 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLCNMKMC_00374 3.3e-71 ywhA K Transcriptional regulator
MLCNMKMC_00375 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MLCNMKMC_00376 5.1e-119 ywhC S Peptidase family M50
MLCNMKMC_00377 2e-94 ywhD S YwhD family
MLCNMKMC_00378 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLCNMKMC_00379 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MLCNMKMC_00380 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
MLCNMKMC_00381 3.7e-28 ywhH S Aminoacyl-tRNA editing domain
MLCNMKMC_00383 2.6e-78 S aspartate phosphatase
MLCNMKMC_00384 6.6e-198 ywhK CO amine dehydrogenase activity
MLCNMKMC_00385 1.9e-245 ywhL CO amine dehydrogenase activity
MLCNMKMC_00387 2.1e-246 L Peptidase, M16
MLCNMKMC_00388 2e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
MLCNMKMC_00389 1e-232 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MLCNMKMC_00390 3.3e-132 cbiO V ABC transporter
MLCNMKMC_00392 1.3e-270 C Fe-S oxidoreductases
MLCNMKMC_00393 1e-07 S Bacteriocin subtilosin A
MLCNMKMC_00394 4.7e-73 ywiB S protein conserved in bacteria
MLCNMKMC_00395 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MLCNMKMC_00396 1.3e-213 narK P COG2223 Nitrate nitrite transporter
MLCNMKMC_00397 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MLCNMKMC_00398 2.6e-137 ywiC S YwiC-like protein
MLCNMKMC_00399 7e-86 arfM T cyclic nucleotide binding
MLCNMKMC_00400 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLCNMKMC_00401 9.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
MLCNMKMC_00402 2.1e-94 narJ 1.7.5.1 C nitrate reductase
MLCNMKMC_00403 9.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
MLCNMKMC_00404 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLCNMKMC_00405 0.0 ywjA V ABC transporter
MLCNMKMC_00406 7.6e-94 ywjB H RibD C-terminal domain
MLCNMKMC_00407 2.7e-42 ywjC
MLCNMKMC_00408 5.6e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MLCNMKMC_00409 2.9e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MLCNMKMC_00410 0.0 fadF C COG0247 Fe-S oxidoreductase
MLCNMKMC_00411 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MLCNMKMC_00412 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLCNMKMC_00413 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLCNMKMC_00414 2.4e-92 ywjG S Domain of unknown function (DUF2529)
MLCNMKMC_00415 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MLCNMKMC_00416 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MLCNMKMC_00417 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLCNMKMC_00418 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLCNMKMC_00419 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MLCNMKMC_00420 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLCNMKMC_00421 1.1e-32 rpmE J Binds the 23S rRNA
MLCNMKMC_00422 2.4e-104 tdk 2.7.1.21 F thymidine kinase
MLCNMKMC_00423 0.0 sfcA 1.1.1.38 C malic enzyme
MLCNMKMC_00424 8.6e-160 ywkB S Membrane transport protein
MLCNMKMC_00425 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MLCNMKMC_00426 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLCNMKMC_00427 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLCNMKMC_00428 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLCNMKMC_00430 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
MLCNMKMC_00431 6.1e-112 spoIIR S stage II sporulation protein R
MLCNMKMC_00432 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MLCNMKMC_00433 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLCNMKMC_00434 1.7e-91 mntP P Probably functions as a manganese efflux pump
MLCNMKMC_00435 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLCNMKMC_00436 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MLCNMKMC_00437 7.2e-95 ywlG S Belongs to the UPF0340 family
MLCNMKMC_00438 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLCNMKMC_00439 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLCNMKMC_00440 2.5e-62 atpI S ATP synthase
MLCNMKMC_00441 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MLCNMKMC_00442 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLCNMKMC_00443 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLCNMKMC_00444 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLCNMKMC_00445 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLCNMKMC_00446 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLCNMKMC_00447 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLCNMKMC_00448 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MLCNMKMC_00449 4.3e-88 ywmA
MLCNMKMC_00450 1.3e-32 ywzB S membrane
MLCNMKMC_00451 1.6e-134 ywmB S TATA-box binding
MLCNMKMC_00452 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLCNMKMC_00453 2e-178 spoIID D Stage II sporulation protein D
MLCNMKMC_00454 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MLCNMKMC_00455 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MLCNMKMC_00457 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLCNMKMC_00458 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLCNMKMC_00459 1.3e-103 S response regulator aspartate phosphatase
MLCNMKMC_00460 3e-84 ywmF S Peptidase M50
MLCNMKMC_00461 3.8e-11 csbD K CsbD-like
MLCNMKMC_00463 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MLCNMKMC_00464 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MLCNMKMC_00465 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MLCNMKMC_00466 1.7e-64 ywnA K Transcriptional regulator
MLCNMKMC_00467 1.6e-114 ywnB S NAD(P)H-binding
MLCNMKMC_00468 2.6e-59 ywnC S Family of unknown function (DUF5362)
MLCNMKMC_00469 4.1e-144 mta K transcriptional
MLCNMKMC_00470 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLCNMKMC_00471 2.2e-70 ywnF S Family of unknown function (DUF5392)
MLCNMKMC_00472 2.7e-14 ywnC S Family of unknown function (DUF5362)
MLCNMKMC_00473 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MLCNMKMC_00474 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MLCNMKMC_00475 3.5e-73 ywnJ S VanZ like family
MLCNMKMC_00476 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MLCNMKMC_00477 1.6e-58 nrgB K Belongs to the P(II) protein family
MLCNMKMC_00478 2.5e-225 amt P Ammonium transporter
MLCNMKMC_00479 2.2e-76
MLCNMKMC_00480 4e-104 phzA Q Isochorismatase family
MLCNMKMC_00481 4.4e-242 ywoD EGP Major facilitator superfamily
MLCNMKMC_00482 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MLCNMKMC_00483 1.2e-231 ywoF P Right handed beta helix region
MLCNMKMC_00484 2.7e-211 ywoG EGP Major facilitator Superfamily
MLCNMKMC_00485 2.1e-70 ywoH K COG1846 Transcriptional regulators
MLCNMKMC_00486 3e-44 spoIIID K Stage III sporulation protein D
MLCNMKMC_00487 3.5e-180 mbl D Rod shape-determining protein
MLCNMKMC_00488 6.9e-126 flhO N flagellar basal body
MLCNMKMC_00489 1.5e-141 flhP N flagellar basal body
MLCNMKMC_00490 2.1e-199 S aspartate phosphatase
MLCNMKMC_00491 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLCNMKMC_00492 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLCNMKMC_00493 1.9e-153 ywpD T Histidine kinase
MLCNMKMC_00494 8e-51 srtA 3.4.22.70 M Sortase family
MLCNMKMC_00495 1.1e-66 ywpF S YwpF-like protein
MLCNMKMC_00496 1.3e-66 ywpG
MLCNMKMC_00497 9.8e-58 ssbB L Single-stranded DNA-binding protein
MLCNMKMC_00498 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
MLCNMKMC_00499 2.3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MLCNMKMC_00500 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLCNMKMC_00501 3.8e-309 ywqB S SWIM zinc finger
MLCNMKMC_00502 1.2e-17
MLCNMKMC_00503 2e-116 ywqC M biosynthesis protein
MLCNMKMC_00504 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MLCNMKMC_00505 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MLCNMKMC_00506 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLCNMKMC_00507 1.3e-153 ywqG S Domain of unknown function (DUF1963)
MLCNMKMC_00508 9.7e-23 S Domain of unknown function (DUF5082)
MLCNMKMC_00509 3.9e-38 ywqI S Family of unknown function (DUF5344)
MLCNMKMC_00510 4.6e-242 ywqJ S Pre-toxin TG
MLCNMKMC_00511 1.9e-24
MLCNMKMC_00512 1.9e-116 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MLCNMKMC_00513 4.9e-162 K Transcriptional regulator
MLCNMKMC_00514 2.2e-99 ywqN S NAD(P)H-dependent
MLCNMKMC_00516 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
MLCNMKMC_00517 2.4e-104 ywrB P Chromate transporter
MLCNMKMC_00518 2.1e-82 ywrC K Transcriptional regulator
MLCNMKMC_00519 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MLCNMKMC_00520 2.9e-54 S Domain of unknown function (DUF4181)
MLCNMKMC_00521 6.9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLCNMKMC_00522 3.6e-12
MLCNMKMC_00523 3.5e-210 cotH M Spore Coat
MLCNMKMC_00524 2.9e-130 cotB
MLCNMKMC_00525 1.1e-124 ywrJ
MLCNMKMC_00526 4.2e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLCNMKMC_00527 1.1e-169 alsR K LysR substrate binding domain
MLCNMKMC_00528 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MLCNMKMC_00529 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MLCNMKMC_00530 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MLCNMKMC_00531 8e-48 ywsA S Protein of unknown function (DUF3892)
MLCNMKMC_00532 4.6e-94 batE T Sh3 type 3 domain protein
MLCNMKMC_00533 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MLCNMKMC_00534 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
MLCNMKMC_00535 9.5e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MLCNMKMC_00536 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLCNMKMC_00537 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLCNMKMC_00538 1.9e-178 rbsR K transcriptional
MLCNMKMC_00539 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MLCNMKMC_00540 8.6e-70 pgsC S biosynthesis protein
MLCNMKMC_00541 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MLCNMKMC_00542 1.4e-20 ywtC
MLCNMKMC_00543 1e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLCNMKMC_00544 9.1e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MLCNMKMC_00545 8.4e-171 ywtF K Transcriptional regulator
MLCNMKMC_00546 7.8e-247 ywtG EGP Major facilitator Superfamily
MLCNMKMC_00547 5.1e-212 gerAC S Spore germination protein
MLCNMKMC_00548 3.2e-198 gerBB E Spore germination protein
MLCNMKMC_00549 3.5e-266 gerBA EG Spore germination protein
MLCNMKMC_00550 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MLCNMKMC_00551 3.6e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLCNMKMC_00552 1.2e-260
MLCNMKMC_00553 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLCNMKMC_00554 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLCNMKMC_00555 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MLCNMKMC_00556 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
MLCNMKMC_00557 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLCNMKMC_00558 1.1e-150 tagG GM Transport permease protein
MLCNMKMC_00559 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLCNMKMC_00560 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLCNMKMC_00562 8.1e-257 ggaA M Glycosyltransferase like family 2
MLCNMKMC_00563 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MLCNMKMC_00564 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLCNMKMC_00565 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLCNMKMC_00566 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MLCNMKMC_00567 6e-38
MLCNMKMC_00568 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MLCNMKMC_00569 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLCNMKMC_00570 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLCNMKMC_00571 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLCNMKMC_00572 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MLCNMKMC_00573 4.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLCNMKMC_00574 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
MLCNMKMC_00575 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
MLCNMKMC_00576 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MLCNMKMC_00577 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MLCNMKMC_00578 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MLCNMKMC_00579 6e-163 yvhJ K Transcriptional regulator
MLCNMKMC_00580 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MLCNMKMC_00581 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MLCNMKMC_00582 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLCNMKMC_00583 7.3e-155 degV S protein conserved in bacteria
MLCNMKMC_00584 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLCNMKMC_00585 5.7e-46 comFB S Late competence development protein ComFB
MLCNMKMC_00586 2.7e-129 comFC S Phosphoribosyl transferase domain
MLCNMKMC_00587 7e-74 yvyF S flagellar protein
MLCNMKMC_00588 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
MLCNMKMC_00589 2.4e-78 flgN NOU FlgN protein
MLCNMKMC_00590 1.2e-264 flgK N flagellar hook-associated protein
MLCNMKMC_00591 2e-155 flgL N Belongs to the bacterial flagellin family
MLCNMKMC_00592 2.6e-50 yviE
MLCNMKMC_00593 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MLCNMKMC_00594 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MLCNMKMC_00595 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLCNMKMC_00596 6.1e-57 flaG N flagellar protein FlaG
MLCNMKMC_00597 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MLCNMKMC_00598 2.9e-69 fliS N flagellar protein FliS
MLCNMKMC_00599 1.9e-08 fliT S bacterial-type flagellum organization
MLCNMKMC_00600 2.8e-66
MLCNMKMC_00601 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLCNMKMC_00602 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLCNMKMC_00603 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLCNMKMC_00604 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MLCNMKMC_00605 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
MLCNMKMC_00606 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MLCNMKMC_00607 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MLCNMKMC_00608 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MLCNMKMC_00609 5.3e-56 swrA S Swarming motility protein
MLCNMKMC_00610 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLCNMKMC_00611 7.9e-228 yvkA EGP Major facilitator Superfamily
MLCNMKMC_00612 7e-101 yvkB K Transcriptional regulator
MLCNMKMC_00613 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MLCNMKMC_00614 1.2e-30 csbA S protein conserved in bacteria
MLCNMKMC_00615 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLCNMKMC_00616 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLCNMKMC_00617 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLCNMKMC_00618 6.7e-34 yvkN
MLCNMKMC_00619 8e-49 yvlA
MLCNMKMC_00620 3.4e-168 yvlB S Putative adhesin
MLCNMKMC_00621 2.6e-26 pspB KT PspC domain
MLCNMKMC_00622 1.2e-50 yvlD S Membrane
MLCNMKMC_00623 2.7e-203 yvmA EGP Major facilitator Superfamily
MLCNMKMC_00624 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_00625 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MLCNMKMC_00626 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
MLCNMKMC_00627 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_00628 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MLCNMKMC_00629 3.6e-134 yvoA K transcriptional
MLCNMKMC_00630 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLCNMKMC_00631 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLCNMKMC_00632 8.3e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLCNMKMC_00633 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLCNMKMC_00634 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
MLCNMKMC_00635 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MLCNMKMC_00636 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MLCNMKMC_00637 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MLCNMKMC_00638 4.5e-140 yvpB NU protein conserved in bacteria
MLCNMKMC_00639 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLCNMKMC_00640 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLCNMKMC_00641 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLCNMKMC_00642 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MLCNMKMC_00643 8.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLCNMKMC_00644 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLCNMKMC_00645 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLCNMKMC_00646 4.4e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MLCNMKMC_00647 2.1e-70
MLCNMKMC_00648 1e-252
MLCNMKMC_00650 0.0 msbA2 3.6.3.44 V ABC transporter
MLCNMKMC_00651 2.4e-278 S COG0457 FOG TPR repeat
MLCNMKMC_00652 1.4e-102 usp CBM50 M protein conserved in bacteria
MLCNMKMC_00653 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLCNMKMC_00654 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLCNMKMC_00655 5.7e-166 rapZ S Displays ATPase and GTPase activities
MLCNMKMC_00656 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MLCNMKMC_00657 1.4e-170 whiA K May be required for sporulation
MLCNMKMC_00658 1.6e-36 crh G Phosphocarrier protein Chr
MLCNMKMC_00659 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MLCNMKMC_00660 1.8e-33
MLCNMKMC_00661 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_00662 5e-193 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MLCNMKMC_00663 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MLCNMKMC_00664 0.0 yxdM V ABC transporter (permease)
MLCNMKMC_00665 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLCNMKMC_00666 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MLCNMKMC_00667 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MLCNMKMC_00668 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
MLCNMKMC_00669 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MLCNMKMC_00670 1.4e-173 yvdE K Transcriptional regulator
MLCNMKMC_00671 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MLCNMKMC_00672 1.1e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MLCNMKMC_00673 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
MLCNMKMC_00674 9.5e-147 malD P transport
MLCNMKMC_00675 2.4e-156 malA S Protein of unknown function (DUF1189)
MLCNMKMC_00676 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MLCNMKMC_00677 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MLCNMKMC_00678 2.2e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MLCNMKMC_00679 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLCNMKMC_00681 1.2e-182 S Patatin-like phospholipase
MLCNMKMC_00682 3.2e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
MLCNMKMC_00683 6.3e-93 yvdQ S Protein of unknown function (DUF3231)
MLCNMKMC_00684 4.1e-50 sugE P Small Multidrug Resistance protein
MLCNMKMC_00685 1.5e-50 ykkC P Small Multidrug Resistance protein
MLCNMKMC_00686 7.4e-106 yvdT K Transcriptional regulator
MLCNMKMC_00687 1.8e-295 yveA E amino acid
MLCNMKMC_00688 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MLCNMKMC_00689 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MLCNMKMC_00690 9.6e-266 pbpE V Beta-lactamase
MLCNMKMC_00691 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MLCNMKMC_00692 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
MLCNMKMC_00693 4.6e-93 padC Q Phenolic acid decarboxylase
MLCNMKMC_00695 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MLCNMKMC_00696 5.7e-77 slr K transcriptional
MLCNMKMC_00697 4e-122 ywqC M biosynthesis protein
MLCNMKMC_00698 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MLCNMKMC_00699 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MLCNMKMC_00700 8e-221 epsD GT4 M Glycosyl transferase 4-like
MLCNMKMC_00701 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLCNMKMC_00702 6e-216 epsF GT4 M Glycosyl transferases group 1
MLCNMKMC_00703 3.1e-206 epsG S EpsG family
MLCNMKMC_00704 1.4e-195 epsH GT2 S Glycosyltransferase like family 2
MLCNMKMC_00705 3.6e-207 epsI GM pyruvyl transferase
MLCNMKMC_00706 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MLCNMKMC_00707 3.4e-259 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLCNMKMC_00708 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLCNMKMC_00709 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MLCNMKMC_00710 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MLCNMKMC_00711 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
MLCNMKMC_00712 1e-31 yvfG S YvfG protein
MLCNMKMC_00713 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MLCNMKMC_00714 1.4e-309 yvfH C L-lactate permease
MLCNMKMC_00715 1e-112 yvfI K COG2186 Transcriptional regulators
MLCNMKMC_00716 1.8e-184 lacR K Transcriptional regulator
MLCNMKMC_00717 5.5e-231 cycB G COG2182 Maltose-binding periplasmic proteins domains
MLCNMKMC_00718 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
MLCNMKMC_00719 7.2e-150 ganQ P transport
MLCNMKMC_00720 0.0 lacA 3.2.1.23 G beta-galactosidase
MLCNMKMC_00721 1e-248 galA 3.2.1.89 G arabinogalactan
MLCNMKMC_00722 2.5e-196 rsbU 3.1.3.3 T response regulator
MLCNMKMC_00723 4.4e-157 rsbQ S Alpha/beta hydrolase family
MLCNMKMC_00724 4.4e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MLCNMKMC_00725 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
MLCNMKMC_00726 4.8e-194 desK 2.7.13.3 T Histidine kinase
MLCNMKMC_00727 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLCNMKMC_00728 2.5e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLCNMKMC_00729 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MLCNMKMC_00730 2e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLCNMKMC_00731 1.8e-195 yvbX S Glycosyl hydrolase
MLCNMKMC_00732 6.2e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MLCNMKMC_00733 8.5e-157 yvbV EG EamA-like transporter family
MLCNMKMC_00734 3.9e-159 yvbU K Transcriptional regulator
MLCNMKMC_00735 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLCNMKMC_00736 5.5e-203 araR K transcriptional
MLCNMKMC_00737 1.6e-252 araE EGP Major facilitator Superfamily
MLCNMKMC_00738 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLCNMKMC_00739 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLCNMKMC_00740 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MLCNMKMC_00741 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLCNMKMC_00742 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MLCNMKMC_00743 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLCNMKMC_00744 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
MLCNMKMC_00745 0.0 tcaA S response to antibiotic
MLCNMKMC_00746 4.2e-124 exoY M Membrane
MLCNMKMC_00747 8.6e-113 yvbH S YvbH-like oligomerisation region
MLCNMKMC_00748 6.4e-103 yvbG U UPF0056 membrane protein
MLCNMKMC_00749 1.4e-98 yvbF K Belongs to the GbsR family
MLCNMKMC_00750 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLCNMKMC_00751 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLCNMKMC_00752 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLCNMKMC_00753 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLCNMKMC_00754 4.5e-45 sdpR K transcriptional
MLCNMKMC_00755 3.1e-94 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MLCNMKMC_00756 4.4e-08
MLCNMKMC_00757 1.4e-170
MLCNMKMC_00758 5.1e-12 S Sporulation delaying protein SdpA
MLCNMKMC_00759 8.7e-61 yvbF K Belongs to the GbsR family
MLCNMKMC_00760 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLCNMKMC_00761 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLCNMKMC_00762 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLCNMKMC_00763 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLCNMKMC_00764 4.2e-226 NT chemotaxis protein
MLCNMKMC_00765 2.2e-54 yodB K transcriptional
MLCNMKMC_00766 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
MLCNMKMC_00767 4e-69 K transcriptional
MLCNMKMC_00768 7.5e-36 yvzC K Transcriptional
MLCNMKMC_00769 3.7e-153 yvaM S Serine aminopeptidase, S33
MLCNMKMC_00770 2.4e-23 secG U Preprotein translocase subunit SecG
MLCNMKMC_00771 5.6e-143 est 3.1.1.1 S Carboxylesterase
MLCNMKMC_00772 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLCNMKMC_00773 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MLCNMKMC_00775 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_00776 4.1e-101 K Bacterial regulatory proteins, tetR family
MLCNMKMC_00777 2.8e-55 yvaE P Small Multidrug Resistance protein
MLCNMKMC_00778 5.7e-73 yvaD S Family of unknown function (DUF5360)
MLCNMKMC_00779 0.0 yvaC S Fusaric acid resistance protein-like
MLCNMKMC_00780 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLCNMKMC_00781 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
MLCNMKMC_00782 2.2e-48 csoR S transcriptional
MLCNMKMC_00783 1.5e-29 copZ P Copper resistance protein CopZ
MLCNMKMC_00784 0.0 copA 3.6.3.54 P P-type ATPase
MLCNMKMC_00785 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLCNMKMC_00786 1.6e-104 bdbD O Thioredoxin
MLCNMKMC_00787 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
MLCNMKMC_00788 4.1e-107 yvgT S membrane
MLCNMKMC_00789 0.0 helD 3.6.4.12 L DNA helicase
MLCNMKMC_00790 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MLCNMKMC_00791 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MLCNMKMC_00792 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MLCNMKMC_00793 5.4e-86 yvgO
MLCNMKMC_00794 9.1e-158 yvgN S reductase
MLCNMKMC_00795 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
MLCNMKMC_00796 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MLCNMKMC_00797 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MLCNMKMC_00798 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLCNMKMC_00799 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MLCNMKMC_00800 6.5e-16 S Small spore protein J (Spore_SspJ)
MLCNMKMC_00801 2.6e-237 yvsH E Arginine ornithine antiporter
MLCNMKMC_00803 2.1e-179 fhuD P ABC transporter
MLCNMKMC_00804 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_00805 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_00806 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
MLCNMKMC_00807 4.8e-176 M Efflux transporter rnd family, mfp subunit
MLCNMKMC_00808 7.1e-124 macB V ABC transporter, ATP-binding protein
MLCNMKMC_00809 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLCNMKMC_00810 1.3e-64 yvrL S Regulatory protein YrvL
MLCNMKMC_00811 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
MLCNMKMC_00812 5.2e-19 S YvrJ protein family
MLCNMKMC_00813 9.5e-98 yvrI K RNA polymerase
MLCNMKMC_00814 7.2e-23
MLCNMKMC_00815 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_00816 0.0 T PhoQ Sensor
MLCNMKMC_00817 1.7e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
MLCNMKMC_00818 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_00819 1.3e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MLCNMKMC_00820 4.7e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_00821 3.9e-243 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MLCNMKMC_00822 1.4e-99 yvqK 2.5.1.17 S Adenosyltransferase
MLCNMKMC_00823 4.8e-227 yvqJ EGP Major facilitator Superfamily
MLCNMKMC_00824 5.6e-62 liaI S membrane
MLCNMKMC_00825 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MLCNMKMC_00826 4.8e-125 liaG S Putative adhesin
MLCNMKMC_00827 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MLCNMKMC_00828 2.7e-186 vraS 2.7.13.3 T Histidine kinase
MLCNMKMC_00829 3.9e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLCNMKMC_00830 1.1e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
MLCNMKMC_00831 1.3e-196 gerAB E Spore germination protein
MLCNMKMC_00832 5.9e-245 gerAA EG Spore germination protein
MLCNMKMC_00833 2.3e-24 S Protein of unknown function (DUF3970)
MLCNMKMC_00834 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLCNMKMC_00835 4.3e-158 yuxN K Transcriptional regulator
MLCNMKMC_00836 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MLCNMKMC_00837 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_00838 1.5e-229 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLCNMKMC_00839 4.7e-79 dps P Ferritin-like domain
MLCNMKMC_00840 2.1e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_00841 1.2e-129 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLCNMKMC_00842 1.1e-24
MLCNMKMC_00843 2.4e-19 S Evidence 4 Homologs of previously reported genes of
MLCNMKMC_00844 6.4e-36 2.6.1.76 E Psort location Cytoplasmic, score
MLCNMKMC_00845 7.1e-07 K PFAM Acetyltransferase (GNAT) family
MLCNMKMC_00846 8.6e-27 EGP Major facilitator Superfamily
MLCNMKMC_00847 8.4e-26 Q methyltransferase
MLCNMKMC_00848 2.2e-75 ecsA V ABC superfamily ATP binding cassette transporter ABC protein
MLCNMKMC_00849 1.3e-23 ecsB U ABC transporter
MLCNMKMC_00851 2.3e-299 pepF2 E COG1164 Oligoendopeptidase F
MLCNMKMC_00852 2.5e-66 S YusW-like protein
MLCNMKMC_00853 3.9e-153 yusV 3.6.3.34 HP ABC transporter
MLCNMKMC_00854 5.6e-39 yusU S Protein of unknown function (DUF2573)
MLCNMKMC_00855 9.7e-158 yusT K LysR substrate binding domain
MLCNMKMC_00856 7.7e-108 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_00857 7.1e-65 yusQ S Tautomerase enzyme
MLCNMKMC_00858 3.2e-292 yusP P Major facilitator superfamily
MLCNMKMC_00859 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
MLCNMKMC_00860 7.1e-53 yusN M Coat F domain
MLCNMKMC_00861 5.1e-40
MLCNMKMC_00862 1.1e-164 fadM E Proline dehydrogenase
MLCNMKMC_00863 8.1e-09 S YuzL-like protein
MLCNMKMC_00864 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MLCNMKMC_00865 2.7e-216 fadA 2.3.1.16 I Belongs to the thiolase family
MLCNMKMC_00866 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MLCNMKMC_00867 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MLCNMKMC_00868 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MLCNMKMC_00869 1.1e-39 yusG S Protein of unknown function (DUF2553)
MLCNMKMC_00870 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MLCNMKMC_00871 5.6e-55 traF CO Thioredoxin
MLCNMKMC_00872 1.2e-55 yusD S SCP-2 sterol transfer family
MLCNMKMC_00873 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLCNMKMC_00874 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MLCNMKMC_00875 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
MLCNMKMC_00876 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLCNMKMC_00877 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MLCNMKMC_00878 1.4e-245 sufD O assembly protein SufD
MLCNMKMC_00879 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLCNMKMC_00880 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MLCNMKMC_00881 3.5e-271 sufB O FeS cluster assembly
MLCNMKMC_00882 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLCNMKMC_00883 1e-41
MLCNMKMC_00885 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MLCNMKMC_00886 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MLCNMKMC_00887 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MLCNMKMC_00888 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MLCNMKMC_00889 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
MLCNMKMC_00890 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
MLCNMKMC_00891 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MLCNMKMC_00892 1.1e-135 yurK K UTRA
MLCNMKMC_00893 1.2e-205 msmX P Belongs to the ABC transporter superfamily
MLCNMKMC_00894 7e-169 bsn L Ribonuclease
MLCNMKMC_00895 6.4e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MLCNMKMC_00896 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MLCNMKMC_00897 6.5e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MLCNMKMC_00898 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MLCNMKMC_00899 1.4e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MLCNMKMC_00900 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MLCNMKMC_00901 8.1e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MLCNMKMC_00902 4.9e-57 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MLCNMKMC_00903 3.2e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MLCNMKMC_00904 2.7e-217 pbuX F xanthine
MLCNMKMC_00905 1.3e-233 pbuX F Permease family
MLCNMKMC_00906 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
MLCNMKMC_00907 3e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MLCNMKMC_00908 3e-62 yunG
MLCNMKMC_00909 4.3e-171 yunF S Protein of unknown function DUF72
MLCNMKMC_00910 5.9e-141 yunE S membrane transporter protein
MLCNMKMC_00911 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MLCNMKMC_00912 4.8e-48 yunC S Domain of unknown function (DUF1805)
MLCNMKMC_00913 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
MLCNMKMC_00914 4.5e-196 lytH M Peptidase, M23
MLCNMKMC_00915 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MLCNMKMC_00916 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLCNMKMC_00917 9.7e-48 yutD S protein conserved in bacteria
MLCNMKMC_00918 1e-75 yutE S Protein of unknown function DUF86
MLCNMKMC_00919 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLCNMKMC_00920 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MLCNMKMC_00921 2e-199 yutH S Spore coat protein
MLCNMKMC_00922 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
MLCNMKMC_00923 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MLCNMKMC_00924 1.2e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLCNMKMC_00925 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MLCNMKMC_00926 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MLCNMKMC_00927 3.5e-57 yuzD S protein conserved in bacteria
MLCNMKMC_00928 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MLCNMKMC_00929 3.2e-39 yuzB S Belongs to the UPF0349 family
MLCNMKMC_00930 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLCNMKMC_00931 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLCNMKMC_00932 3.7e-63 erpA S Belongs to the HesB IscA family
MLCNMKMC_00933 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLCNMKMC_00934 9e-118 paiB K Putative FMN-binding domain
MLCNMKMC_00935 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLCNMKMC_00937 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MLCNMKMC_00938 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
MLCNMKMC_00939 1.9e-26 yuiB S Putative membrane protein
MLCNMKMC_00940 1.8e-116 yuiC S protein conserved in bacteria
MLCNMKMC_00941 1.2e-77 yuiD S protein conserved in bacteria
MLCNMKMC_00942 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLCNMKMC_00943 3.9e-211 yuiF S antiporter
MLCNMKMC_00944 1.1e-93 bioY S Biotin biosynthesis protein
MLCNMKMC_00945 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
MLCNMKMC_00946 1.3e-167 besA S Putative esterase
MLCNMKMC_00947 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_00948 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
MLCNMKMC_00949 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MLCNMKMC_00950 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MLCNMKMC_00951 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_00952 3.8e-36 mbtH S MbtH-like protein
MLCNMKMC_00953 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MLCNMKMC_00954 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MLCNMKMC_00955 6.5e-229 yukF QT Transcriptional regulator
MLCNMKMC_00956 2.8e-45 esxA S Belongs to the WXG100 family
MLCNMKMC_00957 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MLCNMKMC_00958 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
MLCNMKMC_00959 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLCNMKMC_00960 0.0 esaA S type VII secretion protein EsaA
MLCNMKMC_00961 6.6e-65 yueC S Family of unknown function (DUF5383)
MLCNMKMC_00962 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_00963 4.8e-96 yueE S phosphohydrolase
MLCNMKMC_00964 2.9e-24 S Protein of unknown function (DUF2642)
MLCNMKMC_00965 6.1e-72 S Protein of unknown function (DUF2283)
MLCNMKMC_00966 1.9e-190 yueF S transporter activity
MLCNMKMC_00967 2.1e-32 yueG S Spore germination protein gerPA/gerPF
MLCNMKMC_00968 7.4e-39 yueH S YueH-like protein
MLCNMKMC_00969 1.6e-67 yueI S Protein of unknown function (DUF1694)
MLCNMKMC_00970 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
MLCNMKMC_00971 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLCNMKMC_00972 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MLCNMKMC_00973 1.1e-22 yuzC
MLCNMKMC_00975 2.5e-162 comQ H Polyprenyl synthetase
MLCNMKMC_00977 0.0 comP 2.7.13.3 T Histidine kinase
MLCNMKMC_00978 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLCNMKMC_00979 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
MLCNMKMC_00980 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MLCNMKMC_00981 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLCNMKMC_00982 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLCNMKMC_00983 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLCNMKMC_00984 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLCNMKMC_00985 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLCNMKMC_00986 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLCNMKMC_00987 1.9e-14
MLCNMKMC_00988 1.3e-233 maeN C COG3493 Na citrate symporter
MLCNMKMC_00989 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
MLCNMKMC_00990 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
MLCNMKMC_00991 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MLCNMKMC_00992 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MLCNMKMC_00993 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MLCNMKMC_00994 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLCNMKMC_00995 6.3e-78 yufK S Family of unknown function (DUF5366)
MLCNMKMC_00996 6.3e-75 yuxK S protein conserved in bacteria
MLCNMKMC_00997 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MLCNMKMC_00998 3.5e-186 yuxJ EGP Major facilitator Superfamily
MLCNMKMC_01000 1.9e-115 kapD L the KinA pathway to sporulation
MLCNMKMC_01001 2e-70 kapB G Kinase associated protein B
MLCNMKMC_01002 4.6e-233 T PhoQ Sensor
MLCNMKMC_01003 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MLCNMKMC_01004 1.1e-40 yugE S Domain of unknown function (DUF1871)
MLCNMKMC_01005 1e-156 yugF I Hydrolase
MLCNMKMC_01006 1.6e-85 alaR K Transcriptional regulator
MLCNMKMC_01007 2.1e-199 yugH 2.6.1.1 E Aminotransferase
MLCNMKMC_01008 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MLCNMKMC_01009 1.1e-34 yuzA S Domain of unknown function (DUF378)
MLCNMKMC_01010 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MLCNMKMC_01011 2.8e-229 yugK C Dehydrogenase
MLCNMKMC_01012 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MLCNMKMC_01014 1.3e-72 yugN S YugN-like family
MLCNMKMC_01015 2.2e-182 yugO P COG1226 Kef-type K transport systems
MLCNMKMC_01016 1.1e-53 mstX S Membrane-integrating protein Mistic
MLCNMKMC_01017 3.7e-36
MLCNMKMC_01018 1.4e-116 yugP S Zn-dependent protease
MLCNMKMC_01019 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MLCNMKMC_01020 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MLCNMKMC_01021 2.1e-72 yugU S Uncharacterised protein family UPF0047
MLCNMKMC_01022 2.3e-35
MLCNMKMC_01023 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MLCNMKMC_01024 9.3e-225 mcpA NT chemotaxis protein
MLCNMKMC_01025 6.9e-220 mcpA NT chemotaxis protein
MLCNMKMC_01026 8.5e-295 mcpA NT chemotaxis protein
MLCNMKMC_01027 2.1e-237 mcpA NT chemotaxis protein
MLCNMKMC_01028 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MLCNMKMC_01029 3.3e-133 fucR K COG1349 Transcriptional regulators of sugar metabolism
MLCNMKMC_01030 1.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MLCNMKMC_01031 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MLCNMKMC_01032 7.5e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MLCNMKMC_01033 3.3e-183 ygjR S Oxidoreductase
MLCNMKMC_01034 1.3e-194 yubA S transporter activity
MLCNMKMC_01035 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLCNMKMC_01037 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MLCNMKMC_01038 4.9e-274 yubD P Major Facilitator Superfamily
MLCNMKMC_01039 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLCNMKMC_01040 1e-38 yiaA S yiaA/B two helix domain
MLCNMKMC_01041 2.3e-235 ktrB P Potassium
MLCNMKMC_01042 4.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
MLCNMKMC_01043 2.2e-91 yuaB
MLCNMKMC_01044 3.6e-94 yuaC K Belongs to the GbsR family
MLCNMKMC_01045 5.2e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MLCNMKMC_01046 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
MLCNMKMC_01047 3.9e-107 yuaD
MLCNMKMC_01048 3.9e-84 yuaE S DinB superfamily
MLCNMKMC_01049 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MLCNMKMC_01050 3.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
MLCNMKMC_01051 3.2e-92 M1-753 M FR47-like protein
MLCNMKMC_01052 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MLCNMKMC_01061 1.3e-09
MLCNMKMC_01062 7.8e-08
MLCNMKMC_01071 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MLCNMKMC_01072 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLCNMKMC_01073 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MLCNMKMC_01074 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MLCNMKMC_01075 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MLCNMKMC_01076 9.9e-77 tspO T membrane
MLCNMKMC_01077 1.8e-206 cotI S Spore coat protein
MLCNMKMC_01078 4.1e-217 cotSA M Glycosyl transferases group 1
MLCNMKMC_01079 1.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
MLCNMKMC_01081 1.3e-232 ytcC M Glycosyltransferase Family 4
MLCNMKMC_01082 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MLCNMKMC_01083 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLCNMKMC_01084 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
MLCNMKMC_01085 2.6e-132 dksA T COG1734 DnaK suppressor protein
MLCNMKMC_01086 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
MLCNMKMC_01087 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MLCNMKMC_01088 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MLCNMKMC_01089 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLCNMKMC_01090 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MLCNMKMC_01091 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MLCNMKMC_01092 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
MLCNMKMC_01093 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLCNMKMC_01094 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLCNMKMC_01095 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MLCNMKMC_01096 1.1e-24 S Domain of Unknown Function (DUF1540)
MLCNMKMC_01097 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MLCNMKMC_01098 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MLCNMKMC_01099 3.6e-41 rpmE2 J Ribosomal protein L31
MLCNMKMC_01100 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MLCNMKMC_01101 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLCNMKMC_01102 3.6e-73 ytkA S YtkA-like
MLCNMKMC_01104 2.1e-76 dps P Belongs to the Dps family
MLCNMKMC_01105 5.4e-63 ytkC S Bacteriophage holin family
MLCNMKMC_01106 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MLCNMKMC_01107 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLCNMKMC_01108 1.4e-144 ytlC P ABC transporter
MLCNMKMC_01109 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MLCNMKMC_01110 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MLCNMKMC_01111 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MLCNMKMC_01112 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MLCNMKMC_01113 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLCNMKMC_01114 0.0 asnB 6.3.5.4 E Asparagine synthase
MLCNMKMC_01115 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MLCNMKMC_01116 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MLCNMKMC_01117 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MLCNMKMC_01118 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MLCNMKMC_01119 3.3e-106 ytqB J Putative rRNA methylase
MLCNMKMC_01120 2.1e-190 yhcC S Fe-S oxidoreductase
MLCNMKMC_01121 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MLCNMKMC_01123 5.1e-66 ytrA K GntR family transcriptional regulator
MLCNMKMC_01124 1.1e-161 ytrB P abc transporter atp-binding protein
MLCNMKMC_01125 6.1e-169 P ABC-2 family transporter protein
MLCNMKMC_01126 5.9e-148
MLCNMKMC_01127 3.1e-127 ytrE V ABC transporter, ATP-binding protein
MLCNMKMC_01128 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLCNMKMC_01129 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_01130 5.6e-186 T PhoQ Sensor
MLCNMKMC_01131 1.1e-138 bceA V ABC transporter, ATP-binding protein
MLCNMKMC_01132 0.0 bceB V ABC transporter (permease)
MLCNMKMC_01133 2.7e-24 yttA 2.7.13.3 S Pfam Transposase IS66
MLCNMKMC_01134 1.3e-210 yttB EGP Major facilitator Superfamily
MLCNMKMC_01135 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MLCNMKMC_01136 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MLCNMKMC_01137 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLCNMKMC_01138 2.1e-51 ytwF P Sulfurtransferase
MLCNMKMC_01139 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MLCNMKMC_01140 3.7e-143 amyC P ABC transporter (permease)
MLCNMKMC_01141 3.1e-167 amyD P ABC transporter
MLCNMKMC_01142 4.3e-247 msmE G Bacterial extracellular solute-binding protein
MLCNMKMC_01143 1.9e-189 msmR K Transcriptional regulator
MLCNMKMC_01144 1.2e-171 ytaP S Acetyl xylan esterase (AXE1)
MLCNMKMC_01145 4e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MLCNMKMC_01146 1.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MLCNMKMC_01147 1.6e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLCNMKMC_01148 1.9e-121 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MLCNMKMC_01149 2.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MLCNMKMC_01150 3.6e-224 bioI 1.14.14.46 C Cytochrome P450
MLCNMKMC_01151 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MLCNMKMC_01152 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
MLCNMKMC_01153 2e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MLCNMKMC_01154 0.0 ytdP K Transcriptional regulator
MLCNMKMC_01155 5.8e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MLCNMKMC_01156 1.3e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MLCNMKMC_01157 4.3e-71 yteS G transport
MLCNMKMC_01158 2.3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MLCNMKMC_01159 4.8e-117 yteU S Integral membrane protein
MLCNMKMC_01160 3.1e-26 yteV S Sporulation protein Cse60
MLCNMKMC_01161 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MLCNMKMC_01162 6.9e-231 ytfP S HI0933-like protein
MLCNMKMC_01163 7.2e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLCNMKMC_01164 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLCNMKMC_01165 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MLCNMKMC_01166 4.3e-132 ythP V ABC transporter
MLCNMKMC_01167 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
MLCNMKMC_01168 7.2e-226 pbuO S permease
MLCNMKMC_01169 7.1e-272 pepV 3.5.1.18 E Dipeptidase
MLCNMKMC_01170 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLCNMKMC_01171 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLCNMKMC_01172 1.3e-165 ytlQ
MLCNMKMC_01173 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MLCNMKMC_01174 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MLCNMKMC_01175 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
MLCNMKMC_01176 2e-45 ytzH S YtzH-like protein
MLCNMKMC_01177 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLCNMKMC_01178 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MLCNMKMC_01179 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MLCNMKMC_01180 9.8e-52 ytzB S small secreted protein
MLCNMKMC_01181 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MLCNMKMC_01182 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MLCNMKMC_01183 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLCNMKMC_01184 9.8e-149 ytpQ S Belongs to the UPF0354 family
MLCNMKMC_01185 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLCNMKMC_01186 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MLCNMKMC_01187 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MLCNMKMC_01188 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLCNMKMC_01189 6.6e-17 ytxH S COG4980 Gas vesicle protein
MLCNMKMC_01190 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
MLCNMKMC_01191 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MLCNMKMC_01192 1.7e-182 ccpA K catabolite control protein A
MLCNMKMC_01193 7.1e-147 motA N flagellar motor
MLCNMKMC_01194 1.4e-125 motS N Flagellar motor protein
MLCNMKMC_01195 1.9e-225 acuC BQ histone deacetylase
MLCNMKMC_01196 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MLCNMKMC_01197 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MLCNMKMC_01198 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLCNMKMC_01199 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLCNMKMC_01201 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLCNMKMC_01202 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MLCNMKMC_01203 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MLCNMKMC_01204 3.4e-109 yttP K Transcriptional regulator
MLCNMKMC_01205 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MLCNMKMC_01206 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLCNMKMC_01207 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MLCNMKMC_01208 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
MLCNMKMC_01209 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLCNMKMC_01210 2e-29 sspB S spore protein
MLCNMKMC_01211 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLCNMKMC_01212 0.0 ytcJ S amidohydrolase
MLCNMKMC_01213 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLCNMKMC_01214 2.4e-181 sppA OU signal peptide peptidase SppA
MLCNMKMC_01215 1.3e-87 yteJ S RDD family
MLCNMKMC_01216 5.6e-116 ytfI S Protein of unknown function (DUF2953)
MLCNMKMC_01217 8.7e-70 ytfJ S Sporulation protein YtfJ
MLCNMKMC_01218 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLCNMKMC_01219 7e-165 ytxK 2.1.1.72 L DNA methylase
MLCNMKMC_01220 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLCNMKMC_01221 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MLCNMKMC_01222 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLCNMKMC_01223 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
MLCNMKMC_01225 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_01226 1.7e-130 ytkL S Belongs to the UPF0173 family
MLCNMKMC_01227 2.9e-173 ytlI K LysR substrate binding domain
MLCNMKMC_01228 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
MLCNMKMC_01229 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
MLCNMKMC_01230 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
MLCNMKMC_01231 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MLCNMKMC_01232 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
MLCNMKMC_01233 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLCNMKMC_01234 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLCNMKMC_01235 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
MLCNMKMC_01236 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLCNMKMC_01237 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MLCNMKMC_01238 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
MLCNMKMC_01239 1.2e-158 ytnM S membrane transporter protein
MLCNMKMC_01240 8e-241 ytoI K transcriptional regulator containing CBS domains
MLCNMKMC_01241 2.4e-47 ytpI S YtpI-like protein
MLCNMKMC_01242 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MLCNMKMC_01243 9.2e-29
MLCNMKMC_01244 8.2e-69 ytrI
MLCNMKMC_01245 3.2e-56 ytrH S Sporulation protein YtrH
MLCNMKMC_01246 0.0 dnaE 2.7.7.7 L DNA polymerase
MLCNMKMC_01247 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MLCNMKMC_01248 3.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLCNMKMC_01249 8.1e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MLCNMKMC_01250 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLCNMKMC_01251 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MLCNMKMC_01252 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MLCNMKMC_01253 1.7e-191 ytvI S sporulation integral membrane protein YtvI
MLCNMKMC_01254 2.3e-70 yeaL S membrane
MLCNMKMC_01255 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MLCNMKMC_01256 1.8e-242 icd 1.1.1.42 C isocitrate
MLCNMKMC_01257 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MLCNMKMC_01258 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_01259 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MLCNMKMC_01260 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLCNMKMC_01261 3.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLCNMKMC_01262 1.1e-107 ytaF P Probably functions as a manganese efflux pump
MLCNMKMC_01263 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLCNMKMC_01264 8.9e-161 ytbE S reductase
MLCNMKMC_01265 4.9e-205 ytbD EGP Major facilitator Superfamily
MLCNMKMC_01266 9.9e-67 ytcD K Transcriptional regulator
MLCNMKMC_01267 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLCNMKMC_01268 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MLCNMKMC_01269 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLCNMKMC_01270 3.5e-266 dnaB L Membrane attachment protein
MLCNMKMC_01271 3e-173 dnaI L Primosomal protein DnaI
MLCNMKMC_01272 4.9e-111 ytxB S SNARE associated Golgi protein
MLCNMKMC_01273 3.8e-159 ytxC S YtxC-like family
MLCNMKMC_01274 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLCNMKMC_01275 1.5e-149 ysaA S HAD-hyrolase-like
MLCNMKMC_01276 0.0 lytS 2.7.13.3 T Histidine kinase
MLCNMKMC_01277 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
MLCNMKMC_01278 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLCNMKMC_01279 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLCNMKMC_01281 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLCNMKMC_01282 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MLCNMKMC_01283 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLCNMKMC_01284 7.5e-45 ysdA S Membrane
MLCNMKMC_01285 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MLCNMKMC_01286 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
MLCNMKMC_01287 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MLCNMKMC_01288 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MLCNMKMC_01289 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MLCNMKMC_01290 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MLCNMKMC_01291 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MLCNMKMC_01292 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MLCNMKMC_01293 5.3e-253 araN G carbohydrate transport
MLCNMKMC_01294 4.2e-167 araP G carbohydrate transport
MLCNMKMC_01295 3.8e-143 araQ G transport system permease
MLCNMKMC_01296 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MLCNMKMC_01297 0.0 cstA T Carbon starvation protein
MLCNMKMC_01299 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
MLCNMKMC_01300 5.6e-258 glcF C Glycolate oxidase
MLCNMKMC_01301 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
MLCNMKMC_01302 4.4e-208 ysfB KT regulator
MLCNMKMC_01303 2.6e-32 sspI S Belongs to the SspI family
MLCNMKMC_01304 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLCNMKMC_01305 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLCNMKMC_01306 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLCNMKMC_01307 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLCNMKMC_01308 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLCNMKMC_01309 1.3e-85 cvpA S membrane protein, required for colicin V production
MLCNMKMC_01310 0.0 polX L COG1796 DNA polymerase IV (family X)
MLCNMKMC_01311 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLCNMKMC_01312 7.3e-68 yshE S membrane
MLCNMKMC_01313 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLCNMKMC_01314 2.7e-100 fadR K Transcriptional regulator
MLCNMKMC_01315 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MLCNMKMC_01316 4.5e-135 etfB C Electron transfer flavoprotein
MLCNMKMC_01317 2.1e-177 etfA C Electron transfer flavoprotein
MLCNMKMC_01319 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MLCNMKMC_01320 2e-52 trxA O Belongs to the thioredoxin family
MLCNMKMC_01321 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLCNMKMC_01322 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MLCNMKMC_01323 1.2e-79 yslB S Protein of unknown function (DUF2507)
MLCNMKMC_01324 2.4e-107 sdhC C succinate dehydrogenase
MLCNMKMC_01325 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MLCNMKMC_01326 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MLCNMKMC_01327 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MLCNMKMC_01328 3.3e-30 gerE K Transcriptional regulator
MLCNMKMC_01329 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_01330 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MLCNMKMC_01331 2.9e-196 gerM S COG5401 Spore germination protein
MLCNMKMC_01332 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MLCNMKMC_01333 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLCNMKMC_01334 1.4e-92 ysnB S Phosphoesterase
MLCNMKMC_01336 9.1e-134 ysnF S protein conserved in bacteria
MLCNMKMC_01337 7.6e-82 ysnE K acetyltransferase
MLCNMKMC_01339 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MLCNMKMC_01340 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MLCNMKMC_01341 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLCNMKMC_01342 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLCNMKMC_01343 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MLCNMKMC_01344 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLCNMKMC_01345 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLCNMKMC_01346 2.3e-187 ysoA H Tetratricopeptide repeat
MLCNMKMC_01347 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLCNMKMC_01348 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLCNMKMC_01349 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MLCNMKMC_01350 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MLCNMKMC_01351 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MLCNMKMC_01352 1.4e-89 ysxD
MLCNMKMC_01353 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MLCNMKMC_01354 3.6e-146 hemX O cytochrome C
MLCNMKMC_01355 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MLCNMKMC_01356 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MLCNMKMC_01357 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
MLCNMKMC_01358 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MLCNMKMC_01359 1.9e-226 spoVID M stage VI sporulation protein D
MLCNMKMC_01360 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLCNMKMC_01361 1.6e-25
MLCNMKMC_01362 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLCNMKMC_01363 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MLCNMKMC_01364 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MLCNMKMC_01365 1.1e-168 spoIIB S Sporulation related domain
MLCNMKMC_01366 2.8e-102 maf D septum formation protein Maf
MLCNMKMC_01367 5.9e-126 radC E Belongs to the UPF0758 family
MLCNMKMC_01368 1.8e-184 mreB D Rod shape-determining protein MreB
MLCNMKMC_01369 2.8e-157 mreC M Involved in formation and maintenance of cell shape
MLCNMKMC_01370 1.4e-84 mreD M shape-determining protein
MLCNMKMC_01371 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MLCNMKMC_01372 2.5e-144 minD D Belongs to the ParA family
MLCNMKMC_01373 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MLCNMKMC_01374 9.2e-161 spoIVFB S Stage IV sporulation protein
MLCNMKMC_01375 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MLCNMKMC_01376 4.1e-56 ysxB J ribosomal protein
MLCNMKMC_01377 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MLCNMKMC_01378 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MLCNMKMC_01379 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLCNMKMC_01380 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MLCNMKMC_01381 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
MLCNMKMC_01382 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MLCNMKMC_01383 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
MLCNMKMC_01384 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MLCNMKMC_01385 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MLCNMKMC_01386 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MLCNMKMC_01387 9.8e-158 safA M spore coat assembly protein SafA
MLCNMKMC_01388 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLCNMKMC_01389 1.9e-127 yebC K transcriptional regulatory protein
MLCNMKMC_01390 1.8e-262 alsT E Sodium alanine symporter
MLCNMKMC_01391 2.6e-35 S Family of unknown function (DUF5412)
MLCNMKMC_01393 6.5e-119 yrzF T serine threonine protein kinase
MLCNMKMC_01394 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MLCNMKMC_01395 5.3e-253 csbX EGP Major facilitator Superfamily
MLCNMKMC_01396 4.8e-93 bofC S BofC C-terminal domain
MLCNMKMC_01397 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLCNMKMC_01398 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLCNMKMC_01399 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MLCNMKMC_01400 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLCNMKMC_01401 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLCNMKMC_01402 1.1e-38 yajC U Preprotein translocase subunit YajC
MLCNMKMC_01403 1.2e-74 yrzE S Protein of unknown function (DUF3792)
MLCNMKMC_01404 2.2e-114 yrbG S membrane
MLCNMKMC_01405 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLCNMKMC_01406 8e-48 yrzD S Post-transcriptional regulator
MLCNMKMC_01407 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLCNMKMC_01408 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MLCNMKMC_01409 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MLCNMKMC_01410 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MLCNMKMC_01411 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLCNMKMC_01412 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLCNMKMC_01413 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLCNMKMC_01414 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
MLCNMKMC_01416 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
MLCNMKMC_01417 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MLCNMKMC_01418 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MLCNMKMC_01419 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MLCNMKMC_01420 1.2e-70 cymR K Transcriptional regulator
MLCNMKMC_01421 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
MLCNMKMC_01422 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLCNMKMC_01423 1.4e-15 S COG0457 FOG TPR repeat
MLCNMKMC_01424 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLCNMKMC_01425 1.8e-83 yrrD S protein conserved in bacteria
MLCNMKMC_01426 9.8e-31 yrzR
MLCNMKMC_01427 8e-08 S Protein of unknown function (DUF3918)
MLCNMKMC_01428 7.6e-107 glnP P ABC transporter
MLCNMKMC_01429 3.6e-109 gluC P ABC transporter
MLCNMKMC_01430 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
MLCNMKMC_01431 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLCNMKMC_01432 2.7e-170 yrrI S AI-2E family transporter
MLCNMKMC_01433 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLCNMKMC_01434 1.7e-41 yrzL S Belongs to the UPF0297 family
MLCNMKMC_01435 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLCNMKMC_01436 1.2e-45 yrzB S Belongs to the UPF0473 family
MLCNMKMC_01437 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLCNMKMC_01438 5e-119 yrrM 2.1.1.104 S O-methyltransferase
MLCNMKMC_01439 7.8e-174 yegQ O Peptidase U32
MLCNMKMC_01440 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MLCNMKMC_01441 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MLCNMKMC_01442 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLCNMKMC_01443 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MLCNMKMC_01444 4.2e-63 yrrS S Protein of unknown function (DUF1510)
MLCNMKMC_01445 3.5e-26 yrzA S Protein of unknown function (DUF2536)
MLCNMKMC_01446 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MLCNMKMC_01447 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLCNMKMC_01448 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MLCNMKMC_01449 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLCNMKMC_01450 4.6e-35 yrhC S YrhC-like protein
MLCNMKMC_01451 1.4e-78 yrhD S Protein of unknown function (DUF1641)
MLCNMKMC_01452 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MLCNMKMC_01453 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
MLCNMKMC_01454 1.8e-142 focA P Formate nitrite
MLCNMKMC_01457 4.5e-97 yrhH Q methyltransferase
MLCNMKMC_01458 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MLCNMKMC_01459 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MLCNMKMC_01460 1.5e-46 yrhK S YrhK-like protein
MLCNMKMC_01461 0.0 yrhL I Acyltransferase family
MLCNMKMC_01462 3.8e-151 rsiV S Protein of unknown function (DUF3298)
MLCNMKMC_01463 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_01464 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
MLCNMKMC_01465 3.6e-106 yrhP E LysE type translocator
MLCNMKMC_01466 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MLCNMKMC_01467 0.0 levR K PTS system fructose IIA component
MLCNMKMC_01468 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
MLCNMKMC_01469 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MLCNMKMC_01470 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MLCNMKMC_01471 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MLCNMKMC_01472 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MLCNMKMC_01473 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MLCNMKMC_01474 3.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
MLCNMKMC_01475 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
MLCNMKMC_01476 4.3e-47 yraB K helix_turn_helix, mercury resistance
MLCNMKMC_01477 1.1e-49 yraD M Spore coat protein
MLCNMKMC_01478 2.6e-26 yraE
MLCNMKMC_01479 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLCNMKMC_01480 6.4e-63 yraF M Spore coat protein
MLCNMKMC_01481 5.3e-37 yraG
MLCNMKMC_01482 1.3e-66 E Glyoxalase-like domain
MLCNMKMC_01483 2.4e-61 T sh3 domain protein
MLCNMKMC_01484 1.7e-60 T sh3 domain protein
MLCNMKMC_01485 3.2e-155 S Alpha beta hydrolase
MLCNMKMC_01486 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLCNMKMC_01487 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MLCNMKMC_01489 2.4e-206 yraM S PrpF protein
MLCNMKMC_01490 1.2e-163 yraN K Transcriptional regulator
MLCNMKMC_01491 9.5e-226 yraO C Citrate transporter
MLCNMKMC_01492 4.5e-188 yrpG C Aldo/keto reductase family
MLCNMKMC_01493 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_01494 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MLCNMKMC_01496 3e-125 yrpD S Domain of unknown function, YrpD
MLCNMKMC_01497 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MLCNMKMC_01498 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MLCNMKMC_01499 7.6e-168 aadK G Streptomycin adenylyltransferase
MLCNMKMC_01500 1.2e-91 yrdA S DinB family
MLCNMKMC_01501 1.9e-57 S Protein of unknown function (DUF2568)
MLCNMKMC_01502 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
MLCNMKMC_01503 4.1e-231 cypA C Cytochrome P450
MLCNMKMC_01504 4.1e-46 yrdF K ribonuclease inhibitor
MLCNMKMC_01505 2.2e-79 bkdR K helix_turn_helix ASNC type
MLCNMKMC_01506 2.8e-137 azlC E AzlC protein
MLCNMKMC_01507 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MLCNMKMC_01508 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
MLCNMKMC_01510 2.5e-161 gltR K LysR substrate binding domain
MLCNMKMC_01511 1.3e-66 yodA S tautomerase
MLCNMKMC_01512 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
MLCNMKMC_01513 2e-199 trkA P Oxidoreductase
MLCNMKMC_01514 5.9e-160 yrdQ K Transcriptional regulator
MLCNMKMC_01515 1.7e-171 yrdR EG EamA-like transporter family
MLCNMKMC_01516 2.1e-17 S YrzO-like protein
MLCNMKMC_01517 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLCNMKMC_01518 1.4e-83 bltD 2.3.1.57 K FR47-like protein
MLCNMKMC_01519 3.5e-211 blt EGP Major facilitator Superfamily
MLCNMKMC_01520 4.8e-151 bltR K helix_turn_helix, mercury resistance
MLCNMKMC_01522 2.6e-108 yrkC G Cupin domain
MLCNMKMC_01523 7.8e-39 yrkD S protein conserved in bacteria
MLCNMKMC_01524 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
MLCNMKMC_01525 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
MLCNMKMC_01527 1.3e-204 yrkH P Rhodanese Homology Domain
MLCNMKMC_01528 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
MLCNMKMC_01529 4.3e-117 yrkJ S membrane transporter protein
MLCNMKMC_01530 2.8e-79 S Protein of unknown function with HXXEE motif
MLCNMKMC_01531 1.5e-97 ywrO S Flavodoxin-like fold
MLCNMKMC_01532 6e-105 yrkN K Acetyltransferase (GNAT) family
MLCNMKMC_01533 8.2e-224 yrkO P Protein of unknown function (DUF418)
MLCNMKMC_01534 1.1e-127 T Transcriptional regulator
MLCNMKMC_01535 9e-237 yrkQ T Histidine kinase
MLCNMKMC_01536 2e-68 psiE S Protein PsiE homolog
MLCNMKMC_01537 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLCNMKMC_01538 7.1e-100 yqaB E IrrE N-terminal-like domain
MLCNMKMC_01540 1.3e-96 adk 2.7.4.3 F adenylate kinase activity
MLCNMKMC_01541 2e-89 K Transcriptional regulator PadR-like family
MLCNMKMC_01542 7.6e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
MLCNMKMC_01545 1.9e-53 rusA L Endodeoxyribonuclease RusA
MLCNMKMC_01546 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
MLCNMKMC_01547 1.4e-18 wapA M RHS family
MLCNMKMC_01549 2.2e-73 L Transposase
MLCNMKMC_01551 1.8e-27
MLCNMKMC_01552 6.1e-21 ydaT
MLCNMKMC_01555 8.2e-109 S SEC-C Motif Domain Protein
MLCNMKMC_01557 6.3e-34 yqaS L DNA packaging
MLCNMKMC_01558 1.3e-27 S phage terminase, large subunit
MLCNMKMC_01559 3.2e-123 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MLCNMKMC_01561 1.2e-272 L nucleic acid phosphodiester bond hydrolysis
MLCNMKMC_01562 1e-70 K MerR family transcriptional regulator
MLCNMKMC_01563 2.2e-138 yvgN 1.1.1.346 S Reductase
MLCNMKMC_01564 1.4e-156 S Aspartate phosphatase response regulator
MLCNMKMC_01567 2.1e-54 arsR K ArsR family transcriptional regulator
MLCNMKMC_01568 3.7e-65 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLCNMKMC_01569 8.7e-182 arsB 1.20.4.1 P Arsenic resistance protein
MLCNMKMC_01570 4e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MLCNMKMC_01571 1.3e-22 L Helix-turn-helix domain of resolvase
MLCNMKMC_01572 4.6e-140 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
MLCNMKMC_01573 4.2e-64 K BetI-type transcriptional repressor, C-terminal
MLCNMKMC_01574 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLCNMKMC_01575 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
MLCNMKMC_01576 2.3e-133 yqeB
MLCNMKMC_01577 2.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MLCNMKMC_01578 6.7e-105 yqeD S SNARE associated Golgi protein
MLCNMKMC_01579 4.4e-135 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLCNMKMC_01580 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
MLCNMKMC_01582 5.3e-95 yqeG S hydrolase of the HAD superfamily
MLCNMKMC_01583 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MLCNMKMC_01584 3.9e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLCNMKMC_01585 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MLCNMKMC_01586 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLCNMKMC_01587 3.1e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MLCNMKMC_01588 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLCNMKMC_01589 2.9e-139 yqeM Q Methyltransferase
MLCNMKMC_01590 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLCNMKMC_01591 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MLCNMKMC_01592 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MLCNMKMC_01593 0.0 comEC S Competence protein ComEC
MLCNMKMC_01594 4.1e-15 S YqzM-like protein
MLCNMKMC_01595 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
MLCNMKMC_01596 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
MLCNMKMC_01597 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MLCNMKMC_01598 1.5e-222 spoIIP M stage II sporulation protein P
MLCNMKMC_01599 7.2e-53 yqxA S Protein of unknown function (DUF3679)
MLCNMKMC_01600 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLCNMKMC_01601 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MLCNMKMC_01602 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLCNMKMC_01603 4.2e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLCNMKMC_01604 0.0 dnaK O Heat shock 70 kDa protein
MLCNMKMC_01605 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLCNMKMC_01606 5.4e-175 prmA J Methylates ribosomal protein L11
MLCNMKMC_01607 1.8e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLCNMKMC_01608 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MLCNMKMC_01609 1.4e-157 yqeW P COG1283 Na phosphate symporter
MLCNMKMC_01610 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MLCNMKMC_01611 2.5e-61 yqeY S Yqey-like protein
MLCNMKMC_01612 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MLCNMKMC_01613 4.3e-122 yqfA S UPF0365 protein
MLCNMKMC_01614 8.2e-22 yqfB
MLCNMKMC_01615 2.7e-45 yqfC S sporulation protein YqfC
MLCNMKMC_01616 4.3e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MLCNMKMC_01617 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MLCNMKMC_01619 0.0 yqfF S membrane-associated HD superfamily hydrolase
MLCNMKMC_01620 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLCNMKMC_01621 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MLCNMKMC_01622 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MLCNMKMC_01623 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLCNMKMC_01624 8.4e-19 S YqzL-like protein
MLCNMKMC_01625 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
MLCNMKMC_01626 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MLCNMKMC_01627 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MLCNMKMC_01628 4.5e-112 ccpN K CBS domain
MLCNMKMC_01629 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLCNMKMC_01630 4.5e-88 yaiI S Belongs to the UPF0178 family
MLCNMKMC_01631 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLCNMKMC_01632 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLCNMKMC_01633 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MLCNMKMC_01634 1.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
MLCNMKMC_01635 2.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLCNMKMC_01636 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MLCNMKMC_01637 2.9e-14 yqfQ S YqfQ-like protein
MLCNMKMC_01638 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLCNMKMC_01639 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MLCNMKMC_01640 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MLCNMKMC_01641 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MLCNMKMC_01642 1.9e-77 zur P Belongs to the Fur family
MLCNMKMC_01643 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MLCNMKMC_01644 4.3e-62 yqfX S membrane
MLCNMKMC_01645 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MLCNMKMC_01646 5.2e-47 yqfZ M LysM domain
MLCNMKMC_01647 2.2e-75 yqgA
MLCNMKMC_01648 8.5e-134 yqgB S Protein of unknown function (DUF1189)
MLCNMKMC_01649 4e-73 yqgC S protein conserved in bacteria
MLCNMKMC_01650 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MLCNMKMC_01651 2.5e-231 yqgE EGP Major facilitator superfamily
MLCNMKMC_01652 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MLCNMKMC_01653 5.3e-151 pstS P Phosphate
MLCNMKMC_01654 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
MLCNMKMC_01655 3.7e-22 pstA P Phosphate transport system permease
MLCNMKMC_01656 6.2e-126 pstA P Phosphate transport system permease
MLCNMKMC_01657 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLCNMKMC_01658 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLCNMKMC_01659 1.9e-75 yqzC S YceG-like family
MLCNMKMC_01660 9.2e-51 yqzD
MLCNMKMC_01662 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MLCNMKMC_01663 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLCNMKMC_01664 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLCNMKMC_01665 2.5e-09 yqgO
MLCNMKMC_01666 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MLCNMKMC_01667 4.3e-33 yqgQ S Protein conserved in bacteria
MLCNMKMC_01668 5.2e-181 glcK 2.7.1.2 G Glucokinase
MLCNMKMC_01669 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLCNMKMC_01670 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MLCNMKMC_01671 2.7e-199 yqgU
MLCNMKMC_01672 6.9e-50 yqgV S Thiamine-binding protein
MLCNMKMC_01673 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MLCNMKMC_01674 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MLCNMKMC_01675 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MLCNMKMC_01676 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MLCNMKMC_01678 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLCNMKMC_01679 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLCNMKMC_01680 7.2e-175 corA P Mg2 transporter protein
MLCNMKMC_01682 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLCNMKMC_01683 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
MLCNMKMC_01684 1.4e-47 comGC U Required for transformation and DNA binding
MLCNMKMC_01685 4.4e-71 gspH NU protein transport across the cell outer membrane
MLCNMKMC_01686 1.1e-59 comGE
MLCNMKMC_01687 5.5e-49 comGF U Putative Competence protein ComGF
MLCNMKMC_01688 8.8e-44 S ComG operon protein 7
MLCNMKMC_01689 5.2e-26 yqzE S YqzE-like protein
MLCNMKMC_01690 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MLCNMKMC_01691 7.4e-114 yqxM
MLCNMKMC_01692 6.7e-59 sipW 3.4.21.89 U Signal peptidase
MLCNMKMC_01693 1.6e-140 tasA S Cell division protein FtsN
MLCNMKMC_01694 1e-54 sinR K transcriptional
MLCNMKMC_01695 1.2e-24 sinI S Anti-repressor SinI
MLCNMKMC_01696 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
MLCNMKMC_01697 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLCNMKMC_01698 9e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MLCNMKMC_01699 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLCNMKMC_01700 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLCNMKMC_01701 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MLCNMKMC_01702 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MLCNMKMC_01703 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MLCNMKMC_01704 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
MLCNMKMC_01705 2.2e-61 yqhP
MLCNMKMC_01706 2.1e-174 yqhQ S Protein of unknown function (DUF1385)
MLCNMKMC_01707 2.3e-93 yqhR S Conserved membrane protein YqhR
MLCNMKMC_01708 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MLCNMKMC_01709 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MLCNMKMC_01710 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLCNMKMC_01711 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MLCNMKMC_01712 1.2e-171 spoIIIAA S stage III sporulation protein AA
MLCNMKMC_01713 2.9e-85 spoIIIAB S Stage III sporulation protein
MLCNMKMC_01714 7.6e-29 spoIIIAC S stage III sporulation protein AC
MLCNMKMC_01715 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MLCNMKMC_01716 1.3e-197 spoIIIAE S stage III sporulation protein AE
MLCNMKMC_01717 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MLCNMKMC_01718 6.9e-103 spoIIIAG S stage III sporulation protein AG
MLCNMKMC_01719 9.9e-91 spoIIIAH S SpoIIIAH-like protein
MLCNMKMC_01720 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLCNMKMC_01721 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MLCNMKMC_01722 2.1e-67 yqhY S protein conserved in bacteria
MLCNMKMC_01723 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLCNMKMC_01724 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLCNMKMC_01725 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLCNMKMC_01726 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLCNMKMC_01727 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLCNMKMC_01728 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLCNMKMC_01729 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MLCNMKMC_01730 1.7e-78 argR K Regulates arginine biosynthesis genes
MLCNMKMC_01731 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
MLCNMKMC_01732 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MLCNMKMC_01733 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MLCNMKMC_01735 8e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MLCNMKMC_01736 6e-27
MLCNMKMC_01737 7.8e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MLCNMKMC_01738 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLCNMKMC_01739 1.7e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
MLCNMKMC_01740 6.8e-156 hbdA 1.1.1.157 I Dehydrogenase
MLCNMKMC_01741 2e-211 mmgC I acyl-CoA dehydrogenase
MLCNMKMC_01742 8.9e-209 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MLCNMKMC_01743 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MLCNMKMC_01744 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MLCNMKMC_01745 4.1e-34 yqzF S Protein of unknown function (DUF2627)
MLCNMKMC_01746 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MLCNMKMC_01747 3.9e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MLCNMKMC_01748 6.3e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLCNMKMC_01749 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MLCNMKMC_01750 4.9e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLCNMKMC_01751 9.4e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLCNMKMC_01752 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLCNMKMC_01753 2e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLCNMKMC_01754 1.3e-151 bmrR K helix_turn_helix, mercury resistance
MLCNMKMC_01755 7.9e-208 norA EGP Major facilitator Superfamily
MLCNMKMC_01756 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLCNMKMC_01757 9.3e-77 yqiW S Belongs to the UPF0403 family
MLCNMKMC_01758 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
MLCNMKMC_01759 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MLCNMKMC_01760 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLCNMKMC_01761 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
MLCNMKMC_01762 2.3e-98 yqjB S protein conserved in bacteria
MLCNMKMC_01764 2.3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MLCNMKMC_01765 5.4e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLCNMKMC_01766 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MLCNMKMC_01767 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
MLCNMKMC_01768 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLCNMKMC_01769 4.5e-24 yqzJ
MLCNMKMC_01770 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLCNMKMC_01771 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLCNMKMC_01772 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLCNMKMC_01773 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLCNMKMC_01774 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLCNMKMC_01775 2.6e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLCNMKMC_01776 2.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MLCNMKMC_01777 0.0 rocB E arginine degradation protein
MLCNMKMC_01778 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLCNMKMC_01779 2.4e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MLCNMKMC_01780 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_01781 5.4e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MLCNMKMC_01782 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MLCNMKMC_01783 4.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLCNMKMC_01785 2e-225 yqjV G Major Facilitator Superfamily
MLCNMKMC_01787 2e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLCNMKMC_01788 5.7e-50 S YolD-like protein
MLCNMKMC_01789 3.6e-87 yqjY K acetyltransferase
MLCNMKMC_01790 1.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MLCNMKMC_01791 5.7e-194 yqkA K GrpB protein
MLCNMKMC_01792 2.8e-54 yqkB S Belongs to the HesB IscA family
MLCNMKMC_01793 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MLCNMKMC_01794 7.9e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MLCNMKMC_01795 3.1e-12 yqkE S Protein of unknown function (DUF3886)
MLCNMKMC_01796 1.8e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MLCNMKMC_01798 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MLCNMKMC_01799 2.1e-221 yqxK 3.6.4.12 L DNA helicase
MLCNMKMC_01800 4.5e-58 ansR K Transcriptional regulator
MLCNMKMC_01801 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MLCNMKMC_01802 1.4e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MLCNMKMC_01803 3.1e-235 mleN C Na H antiporter
MLCNMKMC_01804 5.5e-242 mleA 1.1.1.38 C malic enzyme
MLCNMKMC_01805 2.1e-29 yqkK
MLCNMKMC_01806 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MLCNMKMC_01807 2.4e-80 fur P Belongs to the Fur family
MLCNMKMC_01808 1.4e-36 S Protein of unknown function (DUF4227)
MLCNMKMC_01809 9.7e-166 xerD L recombinase XerD
MLCNMKMC_01810 1.1e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLCNMKMC_01811 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLCNMKMC_01812 2.6e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MLCNMKMC_01813 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MLCNMKMC_01814 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MLCNMKMC_01815 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLCNMKMC_01816 3.7e-111 spoVAA S Stage V sporulation protein AA
MLCNMKMC_01817 1e-67 spoVAB S Stage V sporulation protein AB
MLCNMKMC_01818 2.3e-78 spoVAC S stage V sporulation protein AC
MLCNMKMC_01819 9e-192 spoVAD I Stage V sporulation protein AD
MLCNMKMC_01820 2.2e-57 spoVAEB S stage V sporulation protein
MLCNMKMC_01821 1.4e-110 spoVAEA S stage V sporulation protein
MLCNMKMC_01822 1.8e-273 spoVAF EG Stage V sporulation protein AF
MLCNMKMC_01823 2e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLCNMKMC_01824 1.3e-149 ypuA S Secreted protein
MLCNMKMC_01825 1.8e-80 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLCNMKMC_01828 7.3e-17 S SNARE associated Golgi protein
MLCNMKMC_01829 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MLCNMKMC_01830 6.2e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLCNMKMC_01831 7.8e-55 ypuD
MLCNMKMC_01832 4.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLCNMKMC_01833 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
MLCNMKMC_01834 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLCNMKMC_01835 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLCNMKMC_01836 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLCNMKMC_01837 1.7e-93 ypuF S Domain of unknown function (DUF309)
MLCNMKMC_01838 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLCNMKMC_01839 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLCNMKMC_01840 4e-98 ypuI S Protein of unknown function (DUF3907)
MLCNMKMC_01841 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MLCNMKMC_01842 3.5e-103 spmA S Spore maturation protein
MLCNMKMC_01843 1.9e-87 spmB S Spore maturation protein
MLCNMKMC_01844 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLCNMKMC_01845 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MLCNMKMC_01846 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MLCNMKMC_01847 1.8e-212 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MLCNMKMC_01848 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_01849 0.0 resE 2.7.13.3 T Histidine kinase
MLCNMKMC_01850 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_01851 1.5e-200 rsiX
MLCNMKMC_01852 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLCNMKMC_01853 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLCNMKMC_01854 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLCNMKMC_01855 4.7e-41 fer C Ferredoxin
MLCNMKMC_01856 5e-201 ypbB 5.1.3.1 S protein conserved in bacteria
MLCNMKMC_01857 3.5e-285 recQ 3.6.4.12 L DNA helicase
MLCNMKMC_01858 1.2e-98 ypbD S metal-dependent membrane protease
MLCNMKMC_01859 2.4e-77 ypbE M Lysin motif
MLCNMKMC_01860 1.4e-80 ypbF S Protein of unknown function (DUF2663)
MLCNMKMC_01861 2e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
MLCNMKMC_01862 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLCNMKMC_01863 2.8e-243 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLCNMKMC_01864 8.7e-176 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MLCNMKMC_01865 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
MLCNMKMC_01866 3.7e-152 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MLCNMKMC_01867 2.7e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MLCNMKMC_01868 8e-109 ypfA M Flagellar protein YcgR
MLCNMKMC_01869 1.8e-23 S Family of unknown function (DUF5359)
MLCNMKMC_01870 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MLCNMKMC_01871 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MLCNMKMC_01872 5e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLCNMKMC_01873 1.4e-07 S YpzI-like protein
MLCNMKMC_01874 1.3e-102 yphA
MLCNMKMC_01875 5.5e-161 seaA S YIEGIA protein
MLCNMKMC_01876 1.6e-28 ypzH
MLCNMKMC_01877 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MLCNMKMC_01878 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MLCNMKMC_01879 1.6e-18 yphE S Protein of unknown function (DUF2768)
MLCNMKMC_01880 5.4e-138 yphF
MLCNMKMC_01881 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLCNMKMC_01882 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLCNMKMC_01883 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MLCNMKMC_01884 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MLCNMKMC_01885 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MLCNMKMC_01886 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLCNMKMC_01887 9.9e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLCNMKMC_01888 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MLCNMKMC_01889 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MLCNMKMC_01890 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLCNMKMC_01891 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLCNMKMC_01892 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MLCNMKMC_01893 1.5e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLCNMKMC_01894 1.8e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLCNMKMC_01895 4.3e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MLCNMKMC_01896 1.2e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MLCNMKMC_01897 5.2e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLCNMKMC_01898 2.7e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLCNMKMC_01899 3.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLCNMKMC_01900 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MLCNMKMC_01901 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLCNMKMC_01902 9.1e-234 S COG0457 FOG TPR repeat
MLCNMKMC_01903 1.1e-98 ypiB S Belongs to the UPF0302 family
MLCNMKMC_01904 4.7e-76 ypiF S Protein of unknown function (DUF2487)
MLCNMKMC_01905 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MLCNMKMC_01906 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MLCNMKMC_01907 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MLCNMKMC_01908 2e-98 ypjA S membrane
MLCNMKMC_01909 1.5e-141 ypjB S sporulation protein
MLCNMKMC_01910 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MLCNMKMC_01911 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MLCNMKMC_01912 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLCNMKMC_01913 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MLCNMKMC_01914 3.4e-129 bshB1 S proteins, LmbE homologs
MLCNMKMC_01915 4.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MLCNMKMC_01916 3.9e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLCNMKMC_01917 1.3e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLCNMKMC_01918 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MLCNMKMC_01919 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MLCNMKMC_01920 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MLCNMKMC_01921 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MLCNMKMC_01922 6.7e-23 ypmA S Protein of unknown function (DUF4264)
MLCNMKMC_01923 3.4e-80 ypmB S protein conserved in bacteria
MLCNMKMC_01924 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MLCNMKMC_01925 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MLCNMKMC_01926 5.7e-129 dnaD L DNA replication protein DnaD
MLCNMKMC_01927 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLCNMKMC_01928 4.7e-93 ypoC
MLCNMKMC_01929 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MLCNMKMC_01930 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLCNMKMC_01931 2.6e-188 yppC S Protein of unknown function (DUF2515)
MLCNMKMC_01934 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
MLCNMKMC_01936 1.2e-48 yppG S YppG-like protein
MLCNMKMC_01937 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
MLCNMKMC_01938 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MLCNMKMC_01939 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MLCNMKMC_01940 1.3e-237 yprB L RNase_H superfamily
MLCNMKMC_01941 3.3e-92 ypsA S Belongs to the UPF0398 family
MLCNMKMC_01942 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLCNMKMC_01943 6.3e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MLCNMKMC_01944 5.8e-50 yqgA
MLCNMKMC_01946 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MLCNMKMC_01947 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_01948 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MLCNMKMC_01949 2.8e-185 ptxS K transcriptional
MLCNMKMC_01950 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MLCNMKMC_01951 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MLCNMKMC_01952 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MLCNMKMC_01953 9.3e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MLCNMKMC_01954 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLCNMKMC_01955 1.6e-228 pbuX F xanthine
MLCNMKMC_01956 4.4e-208 bcsA Q Naringenin-chalcone synthase
MLCNMKMC_01957 5.1e-87 ypbQ S protein conserved in bacteria
MLCNMKMC_01958 0.0 ypbR S Dynamin family
MLCNMKMC_01959 1e-38 ypbS S Protein of unknown function (DUF2533)
MLCNMKMC_01960 2e-07
MLCNMKMC_01961 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MLCNMKMC_01963 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
MLCNMKMC_01964 1.9e-104 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MLCNMKMC_01965 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MLCNMKMC_01966 3e-29 ypeQ S Zinc-finger
MLCNMKMC_01967 8.1e-31 S Protein of unknown function (DUF2564)
MLCNMKMC_01968 3.8e-16 degR
MLCNMKMC_01969 7.9e-31 cspD K Cold-shock protein
MLCNMKMC_01970 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MLCNMKMC_01971 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLCNMKMC_01972 5.2e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MLCNMKMC_01973 1.2e-19 ypgQ S phosphohydrolase
MLCNMKMC_01974 3.4e-50 ypgQ S phosphohydrolase
MLCNMKMC_01975 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
MLCNMKMC_01976 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MLCNMKMC_01977 1.7e-75 yphP S Belongs to the UPF0403 family
MLCNMKMC_01978 2.2e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MLCNMKMC_01979 7.8e-114 ypjP S YpjP-like protein
MLCNMKMC_01980 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MLCNMKMC_01981 2.1e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLCNMKMC_01982 5.1e-95 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLCNMKMC_01983 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLCNMKMC_01984 4.2e-110 hlyIII S protein, Hemolysin III
MLCNMKMC_01985 1.6e-185 pspF K Transcriptional regulator
MLCNMKMC_01986 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLCNMKMC_01987 3.1e-40 ypmP S Protein of unknown function (DUF2535)
MLCNMKMC_01988 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MLCNMKMC_01989 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MLCNMKMC_01990 1.1e-98 ypmS S protein conserved in bacteria
MLCNMKMC_01991 5.5e-29 ypmT S Uncharacterized ympT
MLCNMKMC_01992 2.6e-223 mepA V MATE efflux family protein
MLCNMKMC_01993 1.6e-70 ypoP K transcriptional
MLCNMKMC_01994 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLCNMKMC_01995 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MLCNMKMC_01996 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
MLCNMKMC_01997 2.6e-241 yokA L Recombinase
MLCNMKMC_01999 5.8e-81 yhbS S family acetyltransferase
MLCNMKMC_02000 5.6e-105 yokF 3.1.31.1 L RNA catabolic process
MLCNMKMC_02002 6.1e-141 S Protein of unknown function (DUF4238)
MLCNMKMC_02003 1.7e-64 G SMI1-KNR4 cell-wall
MLCNMKMC_02004 2.3e-123 V HNH endonuclease
MLCNMKMC_02005 8.1e-294 UW nuclease activity
MLCNMKMC_02006 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
MLCNMKMC_02007 9.3e-109 yokK S SMI1 / KNR4 family
MLCNMKMC_02008 6.2e-99 J Acetyltransferase (GNAT) domain
MLCNMKMC_02010 4e-09 S Domain of unknown function (DUF4879)
MLCNMKMC_02012 2.5e-42
MLCNMKMC_02013 1.5e-50 S YolD-like protein
MLCNMKMC_02014 5.8e-233 S impB/mucB/samB family C-terminal domain
MLCNMKMC_02016 7.7e-79 4.6.1.1 T Adenylate and Guanylate cyclase catalytic domain
MLCNMKMC_02018 1.8e-95 S aspartate phosphatase
MLCNMKMC_02019 9.2e-37 S Bacteriophage holin
MLCNMKMC_02021 7.8e-74 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MLCNMKMC_02022 1e-183 M Pectate lyase superfamily protein
MLCNMKMC_02023 7.5e-120
MLCNMKMC_02024 1.4e-292 S Pfam Transposase IS66
MLCNMKMC_02025 1.1e-85 S Phage tail protein
MLCNMKMC_02026 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLCNMKMC_02027 1.3e-109
MLCNMKMC_02028 7.5e-19
MLCNMKMC_02031 5e-88
MLCNMKMC_02033 5.7e-122 xerH L Belongs to the 'phage' integrase family
MLCNMKMC_02034 2.6e-63
MLCNMKMC_02035 4e-84
MLCNMKMC_02036 6.7e-100 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
MLCNMKMC_02037 5.4e-08 S Phage uncharacterised protein (Phage_XkdX)
MLCNMKMC_02038 5.9e-11
MLCNMKMC_02039 2.1e-17
MLCNMKMC_02040 4.5e-45
MLCNMKMC_02043 6.6e-89
MLCNMKMC_02044 4e-130
MLCNMKMC_02045 1.3e-90
MLCNMKMC_02046 3.1e-121
MLCNMKMC_02048 1.1e-68
MLCNMKMC_02049 1.1e-80
MLCNMKMC_02050 1.3e-185
MLCNMKMC_02051 7.8e-94
MLCNMKMC_02052 1.8e-246
MLCNMKMC_02053 3.5e-280
MLCNMKMC_02054 0.0 gp17a S Terminase-like family
MLCNMKMC_02055 1.8e-175
MLCNMKMC_02058 1.2e-227
MLCNMKMC_02060 1.5e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLCNMKMC_02061 0.0
MLCNMKMC_02063 5e-24
MLCNMKMC_02065 5.3e-231 S DNA replication origin binding
MLCNMKMC_02077 2.9e-18
MLCNMKMC_02083 4.1e-13
MLCNMKMC_02084 8e-31
MLCNMKMC_02087 3.9e-35 V HNH endonuclease
MLCNMKMC_02088 1.6e-83
MLCNMKMC_02093 2.2e-39 L Belongs to the 'phage' integrase family
MLCNMKMC_02094 2.2e-246
MLCNMKMC_02095 3.7e-33
MLCNMKMC_02096 1.8e-15 K Transcriptional regulator
MLCNMKMC_02107 1.1e-16 S Protein of unknown function (DUF1273)
MLCNMKMC_02108 2.4e-78 S Protein of unknown function (DUF1273)
MLCNMKMC_02110 2.4e-38
MLCNMKMC_02118 5.4e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
MLCNMKMC_02119 1.8e-127 yoqW S Belongs to the SOS response-associated peptidase family
MLCNMKMC_02122 7.2e-101 rssA S esterase of the alpha-beta hydrolase superfamily
MLCNMKMC_02125 1.5e-08
MLCNMKMC_02127 7.2e-156
MLCNMKMC_02128 7.6e-180 L AAA domain
MLCNMKMC_02129 2.2e-84
MLCNMKMC_02130 6.1e-285 3.6.4.12 J DnaB-like helicase C terminal domain
MLCNMKMC_02131 3.6e-213 L DNA primase activity
MLCNMKMC_02132 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MLCNMKMC_02133 0.0 2.7.7.7 L DNA polymerase
MLCNMKMC_02134 4e-23 S protein conserved in bacteria
MLCNMKMC_02137 3e-79 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
MLCNMKMC_02139 7.3e-18 S methyltransferase activity
MLCNMKMC_02140 2.4e-67 yhdJ 2.1.1.72 L DNA methylase
MLCNMKMC_02145 1.1e-49 M self proteolysis
MLCNMKMC_02150 9.5e-21
MLCNMKMC_02152 1.7e-12 larC 4.99.1.12 FJ Protein conserved in bacteria
MLCNMKMC_02157 3.4e-62 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MLCNMKMC_02158 0.0 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
MLCNMKMC_02160 5e-179 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLCNMKMC_02161 9.8e-36 O Glutaredoxin
MLCNMKMC_02162 8.1e-10
MLCNMKMC_02163 3.2e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MLCNMKMC_02164 1.3e-15 V COG4767 Glycopeptide antibiotics resistance protein
MLCNMKMC_02166 5.2e-161 S Thymidylate synthase
MLCNMKMC_02167 1.5e-63
MLCNMKMC_02171 4.3e-65
MLCNMKMC_02174 2.5e-30 sspB S spore protein
MLCNMKMC_02175 4.6e-162 S Calcineurin-like phosphoesterase
MLCNMKMC_02183 1.1e-10 K Cro/C1-type HTH DNA-binding domain
MLCNMKMC_02184 1.2e-103 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLCNMKMC_02186 1e-62 4.2.1.115 GM Polysaccharide biosynthesis protein
MLCNMKMC_02187 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MLCNMKMC_02188 3.3e-188 cgeB S Spore maturation protein
MLCNMKMC_02189 1.2e-65 cgeA
MLCNMKMC_02190 3.5e-38 cgeC
MLCNMKMC_02191 1e-256 cgeD M maturation of the outermost layer of the spore
MLCNMKMC_02192 2.9e-145 yiiD K acetyltransferase
MLCNMKMC_02194 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLCNMKMC_02195 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLCNMKMC_02196 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLCNMKMC_02197 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
MLCNMKMC_02198 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MLCNMKMC_02199 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
MLCNMKMC_02200 2.9e-47 yokU S YokU-like protein, putative antitoxin
MLCNMKMC_02201 1.4e-36 yozE S Belongs to the UPF0346 family
MLCNMKMC_02202 1.4e-124 yodN
MLCNMKMC_02204 2.8e-24 yozD S YozD-like protein
MLCNMKMC_02205 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
MLCNMKMC_02206 3.6e-54 yodL S YodL-like
MLCNMKMC_02207 5.3e-09
MLCNMKMC_02208 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MLCNMKMC_02209 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MLCNMKMC_02210 1.5e-23 yodI
MLCNMKMC_02211 2.4e-127 yodH Q Methyltransferase
MLCNMKMC_02212 3.4e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MLCNMKMC_02213 3.9e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLCNMKMC_02214 6.2e-28 S Protein of unknown function (DUF3311)
MLCNMKMC_02215 4.9e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
MLCNMKMC_02216 8.5e-113 mhqD S Carboxylesterase
MLCNMKMC_02217 1.4e-107 yodC C nitroreductase
MLCNMKMC_02218 4.4e-55 yodB K transcriptional
MLCNMKMC_02219 8e-64 yodA S tautomerase
MLCNMKMC_02220 1.3e-203 gntP EG COG2610 H gluconate symporter and related permeases
MLCNMKMC_02221 2.6e-09
MLCNMKMC_02222 8.6e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
MLCNMKMC_02223 6.2e-160 rarD S -transporter
MLCNMKMC_02224 2.1e-42
MLCNMKMC_02225 2.2e-60 yojF S Protein of unknown function (DUF1806)
MLCNMKMC_02226 3.7e-125 yojG S deacetylase
MLCNMKMC_02227 1.6e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLCNMKMC_02228 1.4e-243 norM V Multidrug efflux pump
MLCNMKMC_02230 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLCNMKMC_02231 5.3e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MLCNMKMC_02232 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLCNMKMC_02233 1.5e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLCNMKMC_02234 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
MLCNMKMC_02235 0.0 yojO P Von Willebrand factor
MLCNMKMC_02236 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MLCNMKMC_02237 7.7e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MLCNMKMC_02238 8.6e-168 yocS S -transporter
MLCNMKMC_02239 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLCNMKMC_02240 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
MLCNMKMC_02241 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MLCNMKMC_02242 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MLCNMKMC_02243 2.7e-31 yozC
MLCNMKMC_02244 4.2e-56 yozO S Bacterial PH domain
MLCNMKMC_02245 1.9e-36 yocN
MLCNMKMC_02246 1.1e-40 yozN
MLCNMKMC_02247 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
MLCNMKMC_02248 6.6e-34
MLCNMKMC_02249 6.4e-54 yocL
MLCNMKMC_02250 3.3e-83 dksA T general stress protein
MLCNMKMC_02251 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLCNMKMC_02252 0.0 recQ 3.6.4.12 L DNA helicase
MLCNMKMC_02253 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MLCNMKMC_02254 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLCNMKMC_02255 3.2e-198 desK 2.7.13.3 T Histidine kinase
MLCNMKMC_02256 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MLCNMKMC_02257 6.9e-189 yocD 3.4.17.13 V peptidase S66
MLCNMKMC_02258 1.9e-94 yocC
MLCNMKMC_02259 2.2e-145
MLCNMKMC_02260 1.5e-92 yozB S membrane
MLCNMKMC_02261 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLCNMKMC_02262 1e-51 czrA K transcriptional
MLCNMKMC_02263 3.2e-95 yobW
MLCNMKMC_02264 9e-178 yobV K WYL domain
MLCNMKMC_02265 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
MLCNMKMC_02266 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MLCNMKMC_02267 3e-99 yobS K Transcriptional regulator
MLCNMKMC_02268 2.5e-143 yobR 2.3.1.1 J FR47-like protein
MLCNMKMC_02269 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
MLCNMKMC_02270 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MLCNMKMC_02271 0.0 yobO M Pectate lyase superfamily protein
MLCNMKMC_02272 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MLCNMKMC_02273 7.9e-105 yokH G SMI1 / KNR4 family
MLCNMKMC_02274 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLCNMKMC_02275 3e-86 S SMI1-KNR4 cell-wall
MLCNMKMC_02276 2.7e-157 yobJ
MLCNMKMC_02277 0.0 K Psort location Cytoplasmic, score
MLCNMKMC_02278 1.2e-49
MLCNMKMC_02279 2.6e-38 S YolD-like protein
MLCNMKMC_02280 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLCNMKMC_02281 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLCNMKMC_02283 1.7e-207 S aspartate phosphatase
MLCNMKMC_02288 1.8e-178 yobF
MLCNMKMC_02289 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
MLCNMKMC_02290 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
MLCNMKMC_02292 5.7e-58 K Helix-turn-helix
MLCNMKMC_02293 1.4e-37 S TM2 domain
MLCNMKMC_02294 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MLCNMKMC_02295 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MLCNMKMC_02299 5.9e-166 bla 3.5.2.6 V beta-lactamase
MLCNMKMC_02300 1.3e-116 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MLCNMKMC_02301 1.8e-77 yoaW
MLCNMKMC_02302 1.5e-158 yijE EG EamA-like transporter family
MLCNMKMC_02303 4.3e-158 yoaU K LysR substrate binding domain
MLCNMKMC_02304 1.4e-147 yoaT S Protein of unknown function (DUF817)
MLCNMKMC_02305 4.2e-37 yozG K Transcriptional regulator
MLCNMKMC_02306 4.3e-75 yoaS S Protein of unknown function (DUF2975)
MLCNMKMC_02307 2.4e-172 yoaR V vancomycin resistance protein
MLCNMKMC_02308 4.1e-89
MLCNMKMC_02309 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
MLCNMKMC_02310 1.9e-146 yoaP 3.1.3.18 K YoaP-like
MLCNMKMC_02312 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
MLCNMKMC_02314 3.2e-132 yoqW S Belongs to the SOS response-associated peptidase family
MLCNMKMC_02315 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MLCNMKMC_02316 2.3e-111 yoaK S Membrane
MLCNMKMC_02317 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MLCNMKMC_02318 5.6e-280 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MLCNMKMC_02319 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
MLCNMKMC_02320 1.5e-38 S Protein of unknown function (DUF4025)
MLCNMKMC_02321 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
MLCNMKMC_02322 1.9e-33 yoaF
MLCNMKMC_02323 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLCNMKMC_02324 7.3e-186 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLCNMKMC_02325 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MLCNMKMC_02326 6.2e-235 yoaB EGP Major facilitator Superfamily
MLCNMKMC_02327 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLCNMKMC_02328 3.1e-144 yoxB
MLCNMKMC_02329 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
MLCNMKMC_02330 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_02331 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MLCNMKMC_02332 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLCNMKMC_02333 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLCNMKMC_02334 7.8e-155 gltC K Transcriptional regulator
MLCNMKMC_02335 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MLCNMKMC_02336 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MLCNMKMC_02337 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLCNMKMC_02338 2.5e-158 gltR1 K Transcriptional regulator
MLCNMKMC_02339 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MLCNMKMC_02340 3e-34 yoeD G Helix-turn-helix domain
MLCNMKMC_02341 2.2e-96 L Integrase
MLCNMKMC_02343 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
MLCNMKMC_02344 2.3e-246 yoeA V MATE efflux family protein
MLCNMKMC_02345 9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
MLCNMKMC_02346 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MLCNMKMC_02347 2.2e-96 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_02348 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_02349 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_02350 3.8e-290 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_02351 1.2e-75 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_02352 7.4e-51 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_02353 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_02354 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_02355 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MLCNMKMC_02356 2.8e-64 yngL S Protein of unknown function (DUF1360)
MLCNMKMC_02357 1.3e-306 yngK T Glycosyl hydrolase-like 10
MLCNMKMC_02358 1.8e-31 S Family of unknown function (DUF5367)
MLCNMKMC_02359 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MLCNMKMC_02360 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLCNMKMC_02361 1.9e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MLCNMKMC_02362 1.9e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MLCNMKMC_02363 5.8e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MLCNMKMC_02364 1.4e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MLCNMKMC_02365 3.8e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLCNMKMC_02366 2.5e-233 nrnB S phosphohydrolase (DHH superfamily)
MLCNMKMC_02367 1.2e-103 yngC S membrane-associated protein
MLCNMKMC_02368 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLCNMKMC_02369 7.7e-79 yngA S membrane
MLCNMKMC_02370 9.8e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MLCNMKMC_02371 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MLCNMKMC_02373 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MLCNMKMC_02374 8.2e-252 agcS E Sodium alanine symporter
MLCNMKMC_02375 1.3e-57 ynfC
MLCNMKMC_02376 2.3e-12
MLCNMKMC_02377 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLCNMKMC_02378 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLCNMKMC_02379 6.6e-69 yccU S CoA-binding protein
MLCNMKMC_02380 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLCNMKMC_02381 4.1e-49 yneR S Belongs to the HesB IscA family
MLCNMKMC_02382 1.3e-53 yneQ
MLCNMKMC_02383 1.2e-73 yneP S Thioesterase-like superfamily
MLCNMKMC_02384 3.9e-35 tlp S Belongs to the Tlp family
MLCNMKMC_02385 3.1e-08 sspN S Small acid-soluble spore protein N family
MLCNMKMC_02387 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLCNMKMC_02388 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLCNMKMC_02389 2.2e-14 sspO S Belongs to the SspO family
MLCNMKMC_02390 3.9e-19 sspP S Belongs to the SspP family
MLCNMKMC_02391 5.9e-64 hspX O Spore coat protein
MLCNMKMC_02392 4.2e-74 yneK S Protein of unknown function (DUF2621)
MLCNMKMC_02393 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MLCNMKMC_02394 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MLCNMKMC_02395 7.1e-127 ccdA O cytochrome c biogenesis protein
MLCNMKMC_02396 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MLCNMKMC_02397 1.8e-28 yneF S UPF0154 protein
MLCNMKMC_02398 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MLCNMKMC_02399 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLCNMKMC_02400 1.3e-32 ynzC S UPF0291 protein
MLCNMKMC_02401 4.5e-112 yneB L resolvase
MLCNMKMC_02402 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MLCNMKMC_02403 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLCNMKMC_02404 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MLCNMKMC_02405 5.8e-74 yndM S Protein of unknown function (DUF2512)
MLCNMKMC_02406 1.4e-136 yndL S Replication protein
MLCNMKMC_02408 0.0 yndJ S YndJ-like protein
MLCNMKMC_02409 3.2e-115 yndH S Domain of unknown function (DUF4166)
MLCNMKMC_02410 7.7e-154 yndG S DoxX-like family
MLCNMKMC_02411 4.2e-220 gerLC S Spore germination protein
MLCNMKMC_02412 5e-196 gerAB U Spore germination
MLCNMKMC_02413 5.3e-284 gerAA EG Spore germination protein
MLCNMKMC_02416 1.4e-19 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MLCNMKMC_02417 1.8e-71
MLCNMKMC_02418 7.9e-25 tatA U protein secretion
MLCNMKMC_02421 3.2e-133 S Domain of unknown function, YrpD
MLCNMKMC_02423 2.1e-162 S Thymidylate synthase
MLCNMKMC_02426 5.2e-15
MLCNMKMC_02427 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MLCNMKMC_02428 6.3e-84 yncE S Protein of unknown function (DUF2691)
MLCNMKMC_02429 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLCNMKMC_02430 3.5e-247 iolT EGP Major facilitator Superfamily
MLCNMKMC_02431 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
MLCNMKMC_02432 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MLCNMKMC_02433 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MLCNMKMC_02434 1e-215 xylR GK ROK family
MLCNMKMC_02435 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MLCNMKMC_02436 1.8e-254 xynT G MFS/sugar transport protein
MLCNMKMC_02437 3e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MLCNMKMC_02439 4.9e-111 ynaE S Domain of unknown function (DUF3885)
MLCNMKMC_02440 1.5e-22 K Cro/C1-type HTH DNA-binding domain
MLCNMKMC_02441 7.9e-08 S Uncharacterised protein family (UPF0715)
MLCNMKMC_02442 2.6e-73 S CAAX protease self-immunity
MLCNMKMC_02443 2.9e-96 ynaD J Acetyltransferase (GNAT) domain
MLCNMKMC_02444 2.5e-141 ynaC
MLCNMKMC_02445 8.9e-90 G SMI1-KNR4 cell-wall
MLCNMKMC_02446 1.4e-37
MLCNMKMC_02448 6.6e-10
MLCNMKMC_02449 7e-261 glnA 6.3.1.2 E glutamine synthetase
MLCNMKMC_02450 1.1e-68 glnR K transcriptional
MLCNMKMC_02451 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MLCNMKMC_02452 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLCNMKMC_02453 1.7e-176 spoVK O stage V sporulation protein K
MLCNMKMC_02454 4.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLCNMKMC_02455 2e-109 ymaB
MLCNMKMC_02456 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLCNMKMC_02457 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLCNMKMC_02458 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MLCNMKMC_02459 4.5e-22 ymzA
MLCNMKMC_02460 1.4e-22
MLCNMKMC_02461 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MLCNMKMC_02462 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLCNMKMC_02463 2.1e-46 ymaF S YmaF family
MLCNMKMC_02465 5.4e-50 ebrA P Small Multidrug Resistance protein
MLCNMKMC_02466 4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MLCNMKMC_02467 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
MLCNMKMC_02468 1.7e-125 ymaC S Replication protein
MLCNMKMC_02469 1.9e-07 K Transcriptional regulator
MLCNMKMC_02470 4.6e-252 aprX O Belongs to the peptidase S8 family
MLCNMKMC_02471 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
MLCNMKMC_02472 1.2e-61 ymzB
MLCNMKMC_02473 2.5e-233 cypA C Cytochrome P450
MLCNMKMC_02474 0.0 pks13 HQ Beta-ketoacyl synthase
MLCNMKMC_02475 0.0 dhbF IQ polyketide synthase
MLCNMKMC_02476 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
MLCNMKMC_02477 0.0 pfaA Q Polyketide synthase of type I
MLCNMKMC_02478 0.0 rhiB IQ polyketide synthase
MLCNMKMC_02479 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MLCNMKMC_02480 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
MLCNMKMC_02481 1.3e-245 pksG 2.3.3.10 I synthase
MLCNMKMC_02482 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLCNMKMC_02483 1.4e-37 acpK IQ Phosphopantetheine attachment site
MLCNMKMC_02484 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLCNMKMC_02485 2.4e-186 pksD Q Acyl transferase domain
MLCNMKMC_02486 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLCNMKMC_02487 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
MLCNMKMC_02488 4.4e-109 pksA K Transcriptional regulator
MLCNMKMC_02489 1.2e-97 ymcC S Membrane
MLCNMKMC_02491 2.3e-70 S Regulatory protein YrvL
MLCNMKMC_02492 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLCNMKMC_02493 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLCNMKMC_02494 2.2e-88 cotE S Spore coat protein
MLCNMKMC_02495 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MLCNMKMC_02496 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLCNMKMC_02497 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLCNMKMC_02498 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MLCNMKMC_02499 1.2e-36 spoVS S Stage V sporulation protein S
MLCNMKMC_02500 1.9e-152 ymdB S protein conserved in bacteria
MLCNMKMC_02501 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MLCNMKMC_02502 1e-215 pbpX V Beta-lactamase
MLCNMKMC_02503 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLCNMKMC_02504 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
MLCNMKMC_02505 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLCNMKMC_02506 1.9e-124 ymfM S protein conserved in bacteria
MLCNMKMC_02507 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MLCNMKMC_02508 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MLCNMKMC_02509 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MLCNMKMC_02510 1.4e-242 ymfH S zinc protease
MLCNMKMC_02511 2.9e-235 ymfF S Peptidase M16
MLCNMKMC_02512 1.5e-206 ymfD EGP Major facilitator Superfamily
MLCNMKMC_02513 1.4e-133 ymfC K Transcriptional regulator
MLCNMKMC_02514 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MLCNMKMC_02515 4.4e-32 S YlzJ-like protein
MLCNMKMC_02516 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MLCNMKMC_02517 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLCNMKMC_02518 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLCNMKMC_02519 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MLCNMKMC_02520 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLCNMKMC_02521 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MLCNMKMC_02522 1.1e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MLCNMKMC_02523 2.6e-42 ymxH S YlmC YmxH family
MLCNMKMC_02524 4.4e-233 pepR S Belongs to the peptidase M16 family
MLCNMKMC_02525 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MLCNMKMC_02526 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MLCNMKMC_02527 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLCNMKMC_02528 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MLCNMKMC_02529 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLCNMKMC_02530 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLCNMKMC_02531 3e-44 ylxP S protein conserved in bacteria
MLCNMKMC_02532 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLCNMKMC_02533 3.1e-47 ylxQ J ribosomal protein
MLCNMKMC_02534 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MLCNMKMC_02535 1.1e-203 nusA K Participates in both transcription termination and antitermination
MLCNMKMC_02536 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MLCNMKMC_02537 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLCNMKMC_02538 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLCNMKMC_02539 7.7e-233 rasP M zinc metalloprotease
MLCNMKMC_02540 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MLCNMKMC_02541 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MLCNMKMC_02542 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLCNMKMC_02543 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLCNMKMC_02544 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MLCNMKMC_02545 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLCNMKMC_02546 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MLCNMKMC_02547 4.3e-78 ylxL
MLCNMKMC_02548 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLCNMKMC_02549 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MLCNMKMC_02550 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MLCNMKMC_02551 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MLCNMKMC_02552 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MLCNMKMC_02553 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MLCNMKMC_02554 7.5e-158 flhG D Belongs to the ParA family
MLCNMKMC_02555 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
MLCNMKMC_02556 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLCNMKMC_02557 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLCNMKMC_02558 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MLCNMKMC_02559 2.2e-36 fliQ N Role in flagellar biosynthesis
MLCNMKMC_02560 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MLCNMKMC_02561 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
MLCNMKMC_02562 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MLCNMKMC_02563 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLCNMKMC_02564 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLCNMKMC_02565 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MLCNMKMC_02566 8.2e-140 flgG N Flagellar basal body rod
MLCNMKMC_02567 1.7e-72 flgD N Flagellar basal body rod modification protein
MLCNMKMC_02568 1.2e-221 fliK N Flagellar hook-length control protein
MLCNMKMC_02569 7.7e-37 ylxF S MgtE intracellular N domain
MLCNMKMC_02570 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MLCNMKMC_02571 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MLCNMKMC_02572 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MLCNMKMC_02573 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLCNMKMC_02574 2.4e-255 fliF N The M ring may be actively involved in energy transduction
MLCNMKMC_02575 1.9e-31 fliE N Flagellar hook-basal body
MLCNMKMC_02576 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
MLCNMKMC_02577 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MLCNMKMC_02578 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MLCNMKMC_02579 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLCNMKMC_02580 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLCNMKMC_02581 2.5e-169 xerC L tyrosine recombinase XerC
MLCNMKMC_02582 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLCNMKMC_02583 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLCNMKMC_02584 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MLCNMKMC_02585 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLCNMKMC_02586 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MLCNMKMC_02587 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MLCNMKMC_02588 8.5e-291 ylqG
MLCNMKMC_02589 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLCNMKMC_02590 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLCNMKMC_02591 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLCNMKMC_02592 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MLCNMKMC_02593 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLCNMKMC_02594 6.3e-61 ylqD S YlqD protein
MLCNMKMC_02595 4.5e-36 ylqC S Belongs to the UPF0109 family
MLCNMKMC_02596 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MLCNMKMC_02597 1.8e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLCNMKMC_02598 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLCNMKMC_02599 2.9e-87
MLCNMKMC_02600 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLCNMKMC_02601 0.0 smc D Required for chromosome condensation and partitioning
MLCNMKMC_02602 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLCNMKMC_02603 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLCNMKMC_02604 6.1e-129 IQ reductase
MLCNMKMC_02605 2.9e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLCNMKMC_02606 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLCNMKMC_02607 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MLCNMKMC_02608 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLCNMKMC_02609 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MLCNMKMC_02610 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MLCNMKMC_02611 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
MLCNMKMC_02612 5.5e-59 asp S protein conserved in bacteria
MLCNMKMC_02613 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MLCNMKMC_02614 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MLCNMKMC_02615 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MLCNMKMC_02616 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLCNMKMC_02617 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MLCNMKMC_02618 1.6e-140 stp 3.1.3.16 T phosphatase
MLCNMKMC_02619 1.5e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MLCNMKMC_02620 1.9e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLCNMKMC_02621 3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLCNMKMC_02622 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLCNMKMC_02623 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLCNMKMC_02624 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLCNMKMC_02625 1.1e-27 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLCNMKMC_02626 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MLCNMKMC_02627 1.5e-40 ylzA S Belongs to the UPF0296 family
MLCNMKMC_02628 1.5e-155 yloC S stress-induced protein
MLCNMKMC_02629 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MLCNMKMC_02630 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MLCNMKMC_02631 1.8e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MLCNMKMC_02632 1.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MLCNMKMC_02633 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MLCNMKMC_02634 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MLCNMKMC_02635 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MLCNMKMC_02636 1.1e-179 cysP P phosphate transporter
MLCNMKMC_02637 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MLCNMKMC_02639 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLCNMKMC_02640 2.3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLCNMKMC_02641 2.3e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLCNMKMC_02642 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MLCNMKMC_02643 0.0 carB 6.3.5.5 F Belongs to the CarB family
MLCNMKMC_02644 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MLCNMKMC_02645 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLCNMKMC_02646 5.9e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MLCNMKMC_02647 1.3e-230 pyrP F Xanthine uracil
MLCNMKMC_02648 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLCNMKMC_02649 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLCNMKMC_02650 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLCNMKMC_02651 1.9e-62 dksA T COG1734 DnaK suppressor protein
MLCNMKMC_02652 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLCNMKMC_02653 2.6e-67 divIVA D Cell division initiation protein
MLCNMKMC_02654 4.4e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MLCNMKMC_02655 1.3e-39 yggT S membrane
MLCNMKMC_02656 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLCNMKMC_02657 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLCNMKMC_02658 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MLCNMKMC_02659 2.4e-37 ylmC S sporulation protein
MLCNMKMC_02660 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
MLCNMKMC_02661 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MLCNMKMC_02662 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLCNMKMC_02663 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLCNMKMC_02664 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MLCNMKMC_02665 0.0 bpr O COG1404 Subtilisin-like serine proteases
MLCNMKMC_02666 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLCNMKMC_02667 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLCNMKMC_02668 6.2e-58 sbp S small basic protein
MLCNMKMC_02669 5.1e-102 ylxX S protein conserved in bacteria
MLCNMKMC_02670 2.4e-103 ylxW S protein conserved in bacteria
MLCNMKMC_02671 1.7e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLCNMKMC_02672 5.3e-167 murB 1.3.1.98 M cell wall formation
MLCNMKMC_02673 1.6e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLCNMKMC_02674 5.7e-186 spoVE D Belongs to the SEDS family
MLCNMKMC_02675 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLCNMKMC_02676 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLCNMKMC_02677 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLCNMKMC_02678 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MLCNMKMC_02679 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MLCNMKMC_02680 3.7e-44 ftsL D Essential cell division protein
MLCNMKMC_02681 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLCNMKMC_02682 2.9e-78 mraZ K Belongs to the MraZ family
MLCNMKMC_02683 1.3e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MLCNMKMC_02684 3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLCNMKMC_02685 4e-89 ylbP K n-acetyltransferase
MLCNMKMC_02686 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MLCNMKMC_02687 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MLCNMKMC_02688 2.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MLCNMKMC_02690 2.8e-235 ylbM S Belongs to the UPF0348 family
MLCNMKMC_02691 6.8e-187 ylbL T Belongs to the peptidase S16 family
MLCNMKMC_02692 1.7e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
MLCNMKMC_02693 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
MLCNMKMC_02694 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLCNMKMC_02695 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
MLCNMKMC_02696 3.7e-38 ylbG S UPF0298 protein
MLCNMKMC_02697 1.8e-75 ylbF S Belongs to the UPF0342 family
MLCNMKMC_02698 6.7e-37 ylbE S YlbE-like protein
MLCNMKMC_02699 4.1e-63 ylbD S Putative coat protein
MLCNMKMC_02700 3e-201 ylbC S protein with SCP PR1 domains
MLCNMKMC_02701 2.6e-74 ylbB T COG0517 FOG CBS domain
MLCNMKMC_02702 7e-62 ylbA S YugN-like family
MLCNMKMC_02703 3e-167 ctaG S cytochrome c oxidase
MLCNMKMC_02704 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MLCNMKMC_02705 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MLCNMKMC_02706 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLCNMKMC_02707 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MLCNMKMC_02708 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLCNMKMC_02709 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MLCNMKMC_02710 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLCNMKMC_02711 4.5e-214 ftsW D Belongs to the SEDS family
MLCNMKMC_02712 8.7e-44 ylaN S Belongs to the UPF0358 family
MLCNMKMC_02713 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
MLCNMKMC_02714 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLCNMKMC_02715 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MLCNMKMC_02716 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLCNMKMC_02717 2.5e-32 ylaI S protein conserved in bacteria
MLCNMKMC_02718 4.2e-47 ylaH S YlaH-like protein
MLCNMKMC_02719 0.0 typA T GTP-binding protein TypA
MLCNMKMC_02720 8.2e-22 S Family of unknown function (DUF5325)
MLCNMKMC_02721 1.8e-38 ylaE
MLCNMKMC_02722 1.2e-11 sigC S Putative zinc-finger
MLCNMKMC_02723 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_02724 2.7e-42 ylaB
MLCNMKMC_02725 0.0 ylaA
MLCNMKMC_02726 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MLCNMKMC_02727 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MLCNMKMC_02728 6.9e-78 ykzC S Acetyltransferase (GNAT) family
MLCNMKMC_02729 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
MLCNMKMC_02730 7.1e-26 ykzI
MLCNMKMC_02731 7.1e-118 yktB S Belongs to the UPF0637 family
MLCNMKMC_02732 1.6e-42 yktA S Belongs to the UPF0223 family
MLCNMKMC_02733 3.5e-277 speA 4.1.1.19 E Arginine
MLCNMKMC_02734 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MLCNMKMC_02735 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLCNMKMC_02736 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLCNMKMC_02737 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLCNMKMC_02738 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLCNMKMC_02739 2e-115 recN L Putative cell-wall binding lipoprotein
MLCNMKMC_02741 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLCNMKMC_02742 1.4e-147 ykrA S hydrolases of the HAD superfamily
MLCNMKMC_02743 8.2e-31 ykzG S Belongs to the UPF0356 family
MLCNMKMC_02744 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLCNMKMC_02745 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLCNMKMC_02746 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MLCNMKMC_02747 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MLCNMKMC_02748 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLCNMKMC_02749 1.5e-43 abrB K of stationary sporulation gene expression
MLCNMKMC_02750 7.7e-183 mreB D Rod-share determining protein MreBH
MLCNMKMC_02751 1.1e-12 S Uncharacterized protein YkpC
MLCNMKMC_02752 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MLCNMKMC_02753 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLCNMKMC_02754 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLCNMKMC_02755 8.1e-39 ykoA
MLCNMKMC_02756 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLCNMKMC_02757 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MLCNMKMC_02758 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MLCNMKMC_02759 3.1e-136 fruR K Transcriptional regulator
MLCNMKMC_02760 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLCNMKMC_02761 2.5e-124 macB V ABC transporter, ATP-binding protein
MLCNMKMC_02762 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLCNMKMC_02763 1e-117 yknW S Yip1 domain
MLCNMKMC_02764 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLCNMKMC_02765 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLCNMKMC_02766 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MLCNMKMC_02767 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MLCNMKMC_02768 1.1e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MLCNMKMC_02769 1.7e-243 moeA 2.10.1.1 H molybdopterin
MLCNMKMC_02770 4.5e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLCNMKMC_02771 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MLCNMKMC_02772 2.9e-147 yknT
MLCNMKMC_02773 5.8e-95 rok K Repressor of ComK
MLCNMKMC_02774 4.4e-82 ykuV CO thiol-disulfide
MLCNMKMC_02775 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MLCNMKMC_02776 8.8e-142 ykuT M Mechanosensitive ion channel
MLCNMKMC_02777 9e-37 ykuS S Belongs to the UPF0180 family
MLCNMKMC_02778 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLCNMKMC_02779 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLCNMKMC_02780 3.2e-80 fld C Flavodoxin
MLCNMKMC_02781 3.2e-177 ykuO
MLCNMKMC_02782 5.7e-88 fld C Flavodoxin domain
MLCNMKMC_02783 3.5e-168 ccpC K Transcriptional regulator
MLCNMKMC_02784 1.6e-76 ykuL S CBS domain
MLCNMKMC_02785 3.9e-27 ykzF S Antirepressor AbbA
MLCNMKMC_02786 4.4e-94 ykuK S Ribonuclease H-like
MLCNMKMC_02787 3.9e-37 ykuJ S protein conserved in bacteria
MLCNMKMC_02788 5.2e-234 ykuI T Diguanylate phosphodiesterase
MLCNMKMC_02790 0.0 3.2.1.132 M Putative peptidoglycan binding domain
MLCNMKMC_02791 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_02792 9.4e-166 ykuE S Metallophosphoesterase
MLCNMKMC_02793 4.6e-88 ykuD S protein conserved in bacteria
MLCNMKMC_02794 1.6e-238 ykuC EGP Major facilitator Superfamily
MLCNMKMC_02795 1.7e-84 ykyB S YkyB-like protein
MLCNMKMC_02796 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MLCNMKMC_02797 2.2e-15
MLCNMKMC_02798 8e-224 patA 2.6.1.1 E Aminotransferase
MLCNMKMC_02799 0.0 pilS 2.7.13.3 T Histidine kinase
MLCNMKMC_02800 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MLCNMKMC_02801 8e-124 ykwD J protein with SCP PR1 domains
MLCNMKMC_02802 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MLCNMKMC_02803 2e-264 mcpC NT chemotaxis protein
MLCNMKMC_02804 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLCNMKMC_02805 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
MLCNMKMC_02806 7.2e-39 splA S Transcriptional regulator
MLCNMKMC_02807 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLCNMKMC_02808 2.1e-39 ptsH G phosphocarrier protein HPr
MLCNMKMC_02809 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLCNMKMC_02810 4.5e-128 glcT K antiterminator
MLCNMKMC_02812 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
MLCNMKMC_02814 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MLCNMKMC_02815 3.8e-09
MLCNMKMC_02816 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLCNMKMC_02817 4.9e-90 stoA CO thiol-disulfide
MLCNMKMC_02818 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLCNMKMC_02819 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
MLCNMKMC_02820 2.8e-28
MLCNMKMC_02821 6e-25 ykvS S protein conserved in bacteria
MLCNMKMC_02822 5.6e-46 ykvR S Protein of unknown function (DUF3219)
MLCNMKMC_02823 8.5e-133 G Glycosyl hydrolases family 18
MLCNMKMC_02824 1.2e-35 3.5.1.104 M LysM domain
MLCNMKMC_02825 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
MLCNMKMC_02826 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
MLCNMKMC_02827 2e-61 ykvN K Transcriptional regulator
MLCNMKMC_02828 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLCNMKMC_02829 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MLCNMKMC_02830 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MLCNMKMC_02831 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLCNMKMC_02832 8.7e-182 ykvI S membrane
MLCNMKMC_02833 0.0 clpE O Belongs to the ClpA ClpB family
MLCNMKMC_02834 2.7e-138 motA N flagellar motor
MLCNMKMC_02835 2.5e-125 motB N Flagellar motor protein
MLCNMKMC_02836 1.3e-75 ykvE K transcriptional
MLCNMKMC_02837 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLCNMKMC_02838 1.4e-64 eag
MLCNMKMC_02839 6.4e-09 S Spo0E like sporulation regulatory protein
MLCNMKMC_02840 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
MLCNMKMC_02841 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MLCNMKMC_02842 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MLCNMKMC_02843 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MLCNMKMC_02844 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MLCNMKMC_02845 8e-232 mtnE 2.6.1.83 E Aminotransferase
MLCNMKMC_02846 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLCNMKMC_02847 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MLCNMKMC_02848 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MLCNMKMC_02850 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLCNMKMC_02851 0.0 kinE 2.7.13.3 T Histidine kinase
MLCNMKMC_02852 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MLCNMKMC_02853 4.5e-22 ykzE
MLCNMKMC_02854 1.2e-10 ydfR S Protein of unknown function (DUF421)
MLCNMKMC_02855 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MLCNMKMC_02856 1.2e-155 htpX O Belongs to the peptidase M48B family
MLCNMKMC_02857 1.5e-124 ykrK S Domain of unknown function (DUF1836)
MLCNMKMC_02858 1.9e-26 sspD S small acid-soluble spore protein
MLCNMKMC_02859 8.2e-117 rsgI S Anti-sigma factor N-terminus
MLCNMKMC_02860 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLCNMKMC_02861 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MLCNMKMC_02862 1.4e-116 ykoX S membrane-associated protein
MLCNMKMC_02863 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MLCNMKMC_02864 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLCNMKMC_02865 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MLCNMKMC_02866 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLCNMKMC_02867 0.0 ykoS
MLCNMKMC_02868 9.2e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MLCNMKMC_02869 1.1e-98 ykoP G polysaccharide deacetylase
MLCNMKMC_02870 3.6e-218 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MLCNMKMC_02871 1.3e-81 mhqR K transcriptional
MLCNMKMC_02872 3.4e-25 ykoL
MLCNMKMC_02873 5.9e-18
MLCNMKMC_02874 1.4e-53 tnrA K transcriptional
MLCNMKMC_02875 2.2e-222 mgtE P Acts as a magnesium transporter
MLCNMKMC_02878 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MLCNMKMC_02879 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
MLCNMKMC_02880 2.6e-242 ykoH 2.7.13.3 T Histidine kinase
MLCNMKMC_02881 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_02882 1.1e-109 ykoF S YKOF-related Family
MLCNMKMC_02883 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
MLCNMKMC_02884 2.2e-304 P ABC transporter, ATP-binding protein
MLCNMKMC_02885 5.3e-136 ykoC P Cobalt transport protein
MLCNMKMC_02886 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLCNMKMC_02887 5e-176 isp O Belongs to the peptidase S8 family
MLCNMKMC_02888 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLCNMKMC_02889 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MLCNMKMC_02891 8.4e-72 ohrB O Organic hydroperoxide resistance protein
MLCNMKMC_02892 4.4e-74 ohrR K COG1846 Transcriptional regulators
MLCNMKMC_02893 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MLCNMKMC_02895 5.3e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLCNMKMC_02896 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLCNMKMC_02897 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MLCNMKMC_02898 7e-50 ykkD P Multidrug resistance protein
MLCNMKMC_02899 3.5e-55 ykkC P Multidrug resistance protein
MLCNMKMC_02900 1.7e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLCNMKMC_02901 5.7e-97 ykkA S Protein of unknown function (DUF664)
MLCNMKMC_02902 2.3e-128 ykjA S Protein of unknown function (DUF421)
MLCNMKMC_02903 7.2e-09
MLCNMKMC_02904 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLCNMKMC_02905 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MLCNMKMC_02906 2e-160 ykgA E Amidinotransferase
MLCNMKMC_02907 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
MLCNMKMC_02908 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
MLCNMKMC_02909 8.5e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLCNMKMC_02910 2.6e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLCNMKMC_02911 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MLCNMKMC_02913 0.0 dppE E ABC transporter substrate-binding protein
MLCNMKMC_02914 1.3e-187 dppD P Belongs to the ABC transporter superfamily
MLCNMKMC_02915 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLCNMKMC_02916 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLCNMKMC_02917 3.3e-152 dppA E D-aminopeptidase
MLCNMKMC_02918 1.4e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MLCNMKMC_02919 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLCNMKMC_02921 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLCNMKMC_02922 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLCNMKMC_02924 4.6e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MLCNMKMC_02925 3.4e-239 steT E amino acid
MLCNMKMC_02926 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MLCNMKMC_02927 5.8e-175 pit P phosphate transporter
MLCNMKMC_02928 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MLCNMKMC_02929 6.7e-23 spoIISB S Stage II sporulation protein SB
MLCNMKMC_02930 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLCNMKMC_02931 6e-39 xhlB S SPP1 phage holin
MLCNMKMC_02932 8.6e-36 xhlA S Haemolysin XhlA
MLCNMKMC_02933 4.6e-11 S Phage uncharacterised protein (Phage_XkdX)
MLCNMKMC_02935 2.6e-142
MLCNMKMC_02936 6.7e-41
MLCNMKMC_02937 6.9e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MLCNMKMC_02938 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MLCNMKMC_02939 9.6e-71 xkdS S Protein of unknown function (DUF2634)
MLCNMKMC_02940 2.1e-39 xkdR S Protein of unknown function (DUF2577)
MLCNMKMC_02941 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
MLCNMKMC_02942 3.7e-122 xkdP S Lysin motif
MLCNMKMC_02943 0.0 xkdO L Transglycosylase SLT domain
MLCNMKMC_02944 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
MLCNMKMC_02945 6.1e-76 xkdM S Phage tail tube protein
MLCNMKMC_02946 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MLCNMKMC_02947 4.3e-74 xkdJ
MLCNMKMC_02948 4.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
MLCNMKMC_02949 3.6e-63 yqbH S Domain of unknown function (DUF3599)
MLCNMKMC_02950 4.3e-62 yqbG S Protein of unknown function (DUF3199)
MLCNMKMC_02951 5.8e-169 xkdG S Phage capsid family
MLCNMKMC_02952 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MLCNMKMC_02953 1.6e-285 yqbA S portal protein
MLCNMKMC_02954 1.5e-252 xtmB S phage terminase, large subunit
MLCNMKMC_02955 5.3e-139 xtmA L phage terminase small subunit
MLCNMKMC_02956 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLCNMKMC_02957 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MLCNMKMC_02960 4.1e-118 xkdC L Bacterial dnaA protein
MLCNMKMC_02961 5.9e-157 xkdB K sequence-specific DNA binding
MLCNMKMC_02963 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MLCNMKMC_02964 1e-110 xkdA E IrrE N-terminal-like domain
MLCNMKMC_02965 4.4e-160 ydbD P Catalase
MLCNMKMC_02966 2.1e-111 yjqB S Pfam:DUF867
MLCNMKMC_02967 1.8e-60 yjqA S Bacterial PH domain
MLCNMKMC_02968 1.3e-168 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MLCNMKMC_02969 5.3e-40 S YCII-related domain
MLCNMKMC_02971 1e-212 S response regulator aspartate phosphatase
MLCNMKMC_02972 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MLCNMKMC_02973 2.3e-78 yjoA S DinB family
MLCNMKMC_02974 7.4e-130 MA20_18170 S membrane transporter protein
MLCNMKMC_02975 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MLCNMKMC_02976 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MLCNMKMC_02977 2.3e-184 exuR K transcriptional
MLCNMKMC_02978 3.7e-227 exuT G Sugar (and other) transporter
MLCNMKMC_02979 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLCNMKMC_02980 5.2e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MLCNMKMC_02981 4.8e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MLCNMKMC_02982 2.5e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MLCNMKMC_02983 9.2e-248 yjmB G symporter YjmB
MLCNMKMC_02984 1.3e-278 uxaC 5.3.1.12 G glucuronate isomerase
MLCNMKMC_02985 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
MLCNMKMC_02986 1.2e-65 yjlC S Protein of unknown function (DUF1641)
MLCNMKMC_02987 1.1e-89 yjlB S Cupin domain
MLCNMKMC_02988 1.3e-174 yjlA EG Putative multidrug resistance efflux transporter
MLCNMKMC_02989 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MLCNMKMC_02990 1.9e-122 ybbM S transport system, permease component
MLCNMKMC_02991 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MLCNMKMC_02992 8.2e-30
MLCNMKMC_02993 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLCNMKMC_02994 5.7e-222 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MLCNMKMC_02996 3.2e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MLCNMKMC_02997 8.7e-07 S Domain of unknown function (DUF4352)
MLCNMKMC_02998 1.3e-94 yjgD S Protein of unknown function (DUF1641)
MLCNMKMC_02999 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MLCNMKMC_03000 1.3e-102 yjgB S Domain of unknown function (DUF4309)
MLCNMKMC_03001 1.2e-45 T PhoQ Sensor
MLCNMKMC_03002 1.1e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
MLCNMKMC_03003 2.3e-20 yjfB S Putative motility protein
MLCNMKMC_03004 9.4e-83 S Protein of unknown function (DUF2690)
MLCNMKMC_03005 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
MLCNMKMC_03007 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLCNMKMC_03008 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
MLCNMKMC_03009 4.2e-29 S Domain of unknown function (DUF4177)
MLCNMKMC_03010 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLCNMKMC_03012 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MLCNMKMC_03013 4.1e-50 yjdF S Protein of unknown function (DUF2992)
MLCNMKMC_03014 3.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLCNMKMC_03015 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MLCNMKMC_03016 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MLCNMKMC_03018 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
MLCNMKMC_03019 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
MLCNMKMC_03020 1.1e-92 yqaS L DNA packaging
MLCNMKMC_03021 4.1e-49 S YjcQ protein
MLCNMKMC_03022 1.6e-72 yjcP
MLCNMKMC_03023 8.5e-81 L Transposase
MLCNMKMC_03026 2.6e-44 yjcN
MLCNMKMC_03027 2.1e-190 S Putative amidase domain
MLCNMKMC_03030 5.4e-212 yjcL S Protein of unknown function (DUF819)
MLCNMKMC_03031 7.7e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
MLCNMKMC_03032 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLCNMKMC_03033 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLCNMKMC_03034 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
MLCNMKMC_03035 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MLCNMKMC_03036 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLCNMKMC_03037 1.7e-38
MLCNMKMC_03038 0.0 yjcD 3.6.4.12 L DNA helicase
MLCNMKMC_03039 2.9e-38 spoVIF S Stage VI sporulation protein F
MLCNMKMC_03042 4.3e-56 yjcA S Protein of unknown function (DUF1360)
MLCNMKMC_03043 1.1e-54 cotV S Spore Coat Protein X and V domain
MLCNMKMC_03044 8.8e-24 cotW
MLCNMKMC_03045 1.6e-72 cotX S Spore Coat Protein X and V domain
MLCNMKMC_03046 7.6e-96 cotY S Spore coat protein Z
MLCNMKMC_03047 4.4e-82 cotZ S Spore coat protein
MLCNMKMC_03048 5.9e-54 yjbX S Spore coat protein
MLCNMKMC_03049 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MLCNMKMC_03050 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLCNMKMC_03051 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLCNMKMC_03052 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MLCNMKMC_03053 2.6e-29 thiS H thiamine diphosphate biosynthetic process
MLCNMKMC_03054 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
MLCNMKMC_03055 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MLCNMKMC_03056 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLCNMKMC_03057 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLCNMKMC_03058 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MLCNMKMC_03059 2.6e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLCNMKMC_03060 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLCNMKMC_03061 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MLCNMKMC_03062 1.6e-61 yjbL S Belongs to the UPF0738 family
MLCNMKMC_03063 1e-99 yjbK S protein conserved in bacteria
MLCNMKMC_03064 3.8e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLCNMKMC_03065 1.1e-71 yjbI S Bacterial-like globin
MLCNMKMC_03066 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MLCNMKMC_03068 1.8e-20
MLCNMKMC_03069 0.0 pepF E oligoendopeptidase F
MLCNMKMC_03070 2.8e-221 yjbF S Competence protein
MLCNMKMC_03071 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLCNMKMC_03072 6e-112 yjbE P Integral membrane protein TerC family
MLCNMKMC_03073 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLCNMKMC_03074 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLCNMKMC_03075 4.1e-210 yjbB EGP Major Facilitator Superfamily
MLCNMKMC_03076 2.7e-171 oppF E Belongs to the ABC transporter superfamily
MLCNMKMC_03077 3.4e-197 oppD P Belongs to the ABC transporter superfamily
MLCNMKMC_03078 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLCNMKMC_03079 1.1e-164 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLCNMKMC_03080 9.4e-308 oppA E ABC transporter substrate-binding protein
MLCNMKMC_03081 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MLCNMKMC_03082 5e-147 yjbA S Belongs to the UPF0736 family
MLCNMKMC_03083 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLCNMKMC_03084 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLCNMKMC_03085 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MLCNMKMC_03086 7.2e-186 appF E Belongs to the ABC transporter superfamily
MLCNMKMC_03087 1.5e-183 appD P Belongs to the ABC transporter superfamily
MLCNMKMC_03088 3e-150 yjaZ O Zn-dependent protease
MLCNMKMC_03089 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLCNMKMC_03090 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLCNMKMC_03091 2.7e-22 yjzB
MLCNMKMC_03092 7.3e-26 comZ S ComZ
MLCNMKMC_03093 2.5e-183 med S Transcriptional activator protein med
MLCNMKMC_03094 6.2e-102 yjaV
MLCNMKMC_03095 1.1e-141 yjaU I carboxylic ester hydrolase activity
MLCNMKMC_03096 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MLCNMKMC_03097 9.5e-28 yjzC S YjzC-like protein
MLCNMKMC_03098 3.6e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLCNMKMC_03099 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MLCNMKMC_03100 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MLCNMKMC_03101 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MLCNMKMC_03102 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MLCNMKMC_03103 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLCNMKMC_03104 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLCNMKMC_03105 1.7e-88 norB G Major Facilitator Superfamily
MLCNMKMC_03106 6e-266 yitY C D-arabinono-1,4-lactone oxidase
MLCNMKMC_03107 1.5e-22 pilT S Proteolipid membrane potential modulator
MLCNMKMC_03108 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MLCNMKMC_03109 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MLCNMKMC_03110 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MLCNMKMC_03111 1.2e-17 S Protein of unknown function (DUF3813)
MLCNMKMC_03112 5e-73 ipi S Intracellular proteinase inhibitor
MLCNMKMC_03113 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MLCNMKMC_03114 8.4e-159 yitS S protein conserved in bacteria
MLCNMKMC_03115 2.2e-311 nprB 3.4.24.28 E Peptidase M4
MLCNMKMC_03116 1.4e-44 yitR S Domain of unknown function (DUF3784)
MLCNMKMC_03117 2e-95
MLCNMKMC_03118 1.5e-58 K Transcriptional regulator PadR-like family
MLCNMKMC_03119 1.5e-97 S Sporulation delaying protein SdpA
MLCNMKMC_03120 1.4e-170
MLCNMKMC_03121 8.5e-94
MLCNMKMC_03122 6.9e-161 cvfB S protein conserved in bacteria
MLCNMKMC_03123 5.6e-54 yajQ S Belongs to the UPF0234 family
MLCNMKMC_03124 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MLCNMKMC_03125 5.8e-82 yjcF S Acetyltransferase (GNAT) domain
MLCNMKMC_03126 2e-160 yitH K Acetyltransferase (GNAT) domain
MLCNMKMC_03127 1.5e-228 yitG EGP Major facilitator Superfamily
MLCNMKMC_03128 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLCNMKMC_03129 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLCNMKMC_03130 5.4e-141 yitD 4.4.1.19 S synthase
MLCNMKMC_03131 1.6e-120 comB 3.1.3.71 H Belongs to the ComB family
MLCNMKMC_03132 8.6e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MLCNMKMC_03133 7.9e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MLCNMKMC_03134 4.2e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MLCNMKMC_03135 9.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLCNMKMC_03136 2e-35 mcbG S Pentapeptide repeats (9 copies)
MLCNMKMC_03137 5.5e-275 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLCNMKMC_03138 1.9e-107 argO S Lysine exporter protein LysE YggA
MLCNMKMC_03139 1.3e-93 yisT S DinB family
MLCNMKMC_03140 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MLCNMKMC_03141 2.4e-184 purR K helix_turn _helix lactose operon repressor
MLCNMKMC_03142 1.2e-160 yisR K Transcriptional regulator
MLCNMKMC_03143 4e-243 yisQ V Mate efflux family protein
MLCNMKMC_03144 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MLCNMKMC_03145 2.1e-88 yizA S Damage-inducible protein DinB
MLCNMKMC_03146 0.0 asnO 6.3.5.4 E Asparagine synthase
MLCNMKMC_03147 3.4e-100 yisN S Protein of unknown function (DUF2777)
MLCNMKMC_03148 0.0 wprA O Belongs to the peptidase S8 family
MLCNMKMC_03149 3e-57 yisL S UPF0344 protein
MLCNMKMC_03150 5.4e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MLCNMKMC_03151 3.1e-175 cotH M Spore Coat
MLCNMKMC_03152 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MLCNMKMC_03153 1.9e-33 gerPA S Spore germination protein
MLCNMKMC_03154 4e-34 gerPB S cell differentiation
MLCNMKMC_03155 1.8e-54 gerPC S Spore germination protein
MLCNMKMC_03156 6.3e-24 gerPD S Spore germination protein
MLCNMKMC_03157 3e-66 gerPE S Spore germination protein GerPE
MLCNMKMC_03158 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MLCNMKMC_03159 3e-50 yisB V COG1403 Restriction endonuclease
MLCNMKMC_03160 0.0 sbcC L COG0419 ATPase involved in DNA repair
MLCNMKMC_03161 6.3e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLCNMKMC_03162 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MLCNMKMC_03163 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MLCNMKMC_03164 6.4e-78 yhjR S Rubrerythrin
MLCNMKMC_03165 0.0 S Sugar transport-related sRNA regulator N-term
MLCNMKMC_03166 5.8e-214 EGP Transmembrane secretion effector
MLCNMKMC_03167 1.6e-200 abrB S membrane
MLCNMKMC_03168 3.8e-187 yhjM 5.1.1.1 K Transcriptional regulator
MLCNMKMC_03169 1.7e-254 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MLCNMKMC_03170 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MLCNMKMC_03171 7.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MLCNMKMC_03172 7.6e-214 glcP G Major Facilitator Superfamily
MLCNMKMC_03173 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_03174 1.1e-281 yhjG CH FAD binding domain
MLCNMKMC_03175 1e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MLCNMKMC_03176 9.1e-110 yhjE S SNARE associated Golgi protein
MLCNMKMC_03177 2.5e-59 yhjD
MLCNMKMC_03178 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MLCNMKMC_03179 2e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLCNMKMC_03180 1.1e-40 yhjA S Excalibur calcium-binding domain
MLCNMKMC_03181 8e-168 IQ Enoyl-(Acyl carrier protein) reductase
MLCNMKMC_03182 9.3e-109 comK K Competence transcription factor
MLCNMKMC_03183 1.3e-32 yhzC S IDEAL
MLCNMKMC_03184 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_03185 1e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MLCNMKMC_03186 1.7e-182 hemAT NT chemotaxis protein
MLCNMKMC_03187 1.1e-90 bioY S BioY family
MLCNMKMC_03188 3.3e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MLCNMKMC_03189 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
MLCNMKMC_03190 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MLCNMKMC_03191 4.8e-158 yfmC M Periplasmic binding protein
MLCNMKMC_03192 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
MLCNMKMC_03193 7.3e-77 VY92_01935 K acetyltransferase
MLCNMKMC_03194 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MLCNMKMC_03195 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
MLCNMKMC_03196 1.9e-65 yhfM
MLCNMKMC_03197 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MLCNMKMC_03198 2.6e-112 yhfK GM NmrA-like family
MLCNMKMC_03199 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
MLCNMKMC_03200 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MLCNMKMC_03201 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLCNMKMC_03202 1.7e-72 3.4.13.21 S ASCH
MLCNMKMC_03203 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MLCNMKMC_03204 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
MLCNMKMC_03205 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLCNMKMC_03206 1e-238 yhgE S YhgE Pip N-terminal domain protein
MLCNMKMC_03207 1.4e-101 yhgD K Transcriptional regulator
MLCNMKMC_03208 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MLCNMKMC_03209 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MLCNMKMC_03210 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MLCNMKMC_03211 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLCNMKMC_03212 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MLCNMKMC_03213 7.5e-17 1.15.1.2 C Rubrerythrin
MLCNMKMC_03214 4.2e-248 yhfA C membrane
MLCNMKMC_03215 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MLCNMKMC_03216 4.8e-115 ecsC S EcsC protein family
MLCNMKMC_03217 1.8e-215 ecsB U ABC transporter
MLCNMKMC_03218 4.6e-137 ecsA V transporter (ATP-binding protein)
MLCNMKMC_03219 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MLCNMKMC_03220 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLCNMKMC_03221 3.6e-80 trpP S Tryptophan transporter TrpP
MLCNMKMC_03222 7e-39 yhaH S YtxH-like protein
MLCNMKMC_03223 1e-113 hpr K Negative regulator of protease production and sporulation
MLCNMKMC_03224 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MLCNMKMC_03225 8.7e-90 yhaK S Putative zincin peptidase
MLCNMKMC_03226 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLCNMKMC_03227 1.6e-21 yhaL S Sporulation protein YhaL
MLCNMKMC_03228 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MLCNMKMC_03229 0.0 yhaN L AAA domain
MLCNMKMC_03230 3.6e-227 yhaO L DNA repair exonuclease
MLCNMKMC_03231 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MLCNMKMC_03232 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
MLCNMKMC_03233 1.1e-26 S YhzD-like protein
MLCNMKMC_03234 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
MLCNMKMC_03236 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MLCNMKMC_03237 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MLCNMKMC_03238 7.1e-294 hemZ H coproporphyrinogen III oxidase
MLCNMKMC_03239 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MLCNMKMC_03240 3.1e-206 yhaZ L DNA alkylation repair enzyme
MLCNMKMC_03241 9.5e-48 yheA S Belongs to the UPF0342 family
MLCNMKMC_03242 6.7e-204 yheB S Belongs to the UPF0754 family
MLCNMKMC_03243 4.3e-216 yheC HJ YheC/D like ATP-grasp
MLCNMKMC_03244 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MLCNMKMC_03245 1.3e-36 yheE S Family of unknown function (DUF5342)
MLCNMKMC_03246 6.3e-28 sspB S spore protein
MLCNMKMC_03247 6.2e-111 yheG GM NAD(P)H-binding
MLCNMKMC_03248 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLCNMKMC_03249 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLCNMKMC_03250 3.4e-84 nhaX T Belongs to the universal stress protein A family
MLCNMKMC_03251 3.1e-232 nhaC C Na H antiporter
MLCNMKMC_03252 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MLCNMKMC_03253 1.7e-151 yheN G deacetylase
MLCNMKMC_03254 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MLCNMKMC_03255 6.6e-204 yhdY M Mechanosensitive ion channel
MLCNMKMC_03257 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLCNMKMC_03258 1.5e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLCNMKMC_03259 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLCNMKMC_03260 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MLCNMKMC_03261 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
MLCNMKMC_03262 4.1e-74 cueR K transcriptional
MLCNMKMC_03263 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLCNMKMC_03264 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLCNMKMC_03265 1.5e-191 yhdN C Aldo keto reductase
MLCNMKMC_03266 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_03267 6.6e-201 yhdL S Sigma factor regulator N-terminal
MLCNMKMC_03268 8.1e-45 yhdK S Sigma-M inhibitor protein
MLCNMKMC_03269 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLCNMKMC_03270 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLCNMKMC_03271 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLCNMKMC_03272 3.4e-250 yhdG E amino acid
MLCNMKMC_03273 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_03274 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
MLCNMKMC_03275 3.8e-162 citR K Transcriptional regulator
MLCNMKMC_03276 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLCNMKMC_03277 2.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MLCNMKMC_03278 2.1e-276 ycgB S Stage V sporulation protein R
MLCNMKMC_03279 4.3e-238 ygxB M Conserved TM helix
MLCNMKMC_03280 1e-75 nsrR K Transcriptional regulator
MLCNMKMC_03281 9e-185 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLCNMKMC_03282 4.8e-54 yhdC S Protein of unknown function (DUF3889)
MLCNMKMC_03283 1.2e-38 yhdB S YhdB-like protein
MLCNMKMC_03284 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MLCNMKMC_03285 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLCNMKMC_03286 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
MLCNMKMC_03287 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MLCNMKMC_03288 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLCNMKMC_03289 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLCNMKMC_03290 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MLCNMKMC_03291 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MLCNMKMC_03292 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLCNMKMC_03293 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLCNMKMC_03294 4.6e-120 yhcW 5.4.2.6 S hydrolase
MLCNMKMC_03295 9.9e-68 yhcV S COG0517 FOG CBS domain
MLCNMKMC_03296 9.3e-68 yhcU S Family of unknown function (DUF5365)
MLCNMKMC_03297 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLCNMKMC_03298 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MLCNMKMC_03299 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MLCNMKMC_03300 5.2e-100 yhcQ M Spore coat protein
MLCNMKMC_03301 2.5e-167 yhcP
MLCNMKMC_03302 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLCNMKMC_03303 3.7e-44 yhcM
MLCNMKMC_03304 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLCNMKMC_03305 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MLCNMKMC_03306 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
MLCNMKMC_03307 1e-30 cspB K Cold-shock protein
MLCNMKMC_03308 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLCNMKMC_03309 1.7e-165 yhcH V ABC transporter, ATP-binding protein
MLCNMKMC_03310 4e-122 yhcG V ABC transporter, ATP-binding protein
MLCNMKMC_03311 1.9e-59 yhcF K Transcriptional regulator
MLCNMKMC_03312 4.6e-55
MLCNMKMC_03313 2.8e-37 yhcC
MLCNMKMC_03314 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MLCNMKMC_03315 3.1e-271 yhcA EGP Major facilitator Superfamily
MLCNMKMC_03316 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MLCNMKMC_03317 2.2e-76 yhbI K DNA-binding transcription factor activity
MLCNMKMC_03318 2.5e-225 yhbH S Belongs to the UPF0229 family
MLCNMKMC_03319 0.0 prkA T Ser protein kinase
MLCNMKMC_03320 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MLCNMKMC_03321 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MLCNMKMC_03322 1.2e-109 yhbD K Protein of unknown function (DUF4004)
MLCNMKMC_03323 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLCNMKMC_03324 4.4e-177 yhbB S Putative amidase domain
MLCNMKMC_03325 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLCNMKMC_03326 7.9e-114 yhzB S B3/4 domain
MLCNMKMC_03328 4.4e-29 K Transcriptional regulator
MLCNMKMC_03329 4.1e-78 ygaO
MLCNMKMC_03330 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLCNMKMC_03332 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MLCNMKMC_03333 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLCNMKMC_03334 1.7e-171 ssuA M Sulfonate ABC transporter
MLCNMKMC_03335 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MLCNMKMC_03336 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MLCNMKMC_03338 1.9e-266 ygaK C Berberine and berberine like
MLCNMKMC_03339 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MLCNMKMC_03340 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MLCNMKMC_03341 3e-27
MLCNMKMC_03342 2.7e-143 spo0M S COG4326 Sporulation control protein
MLCNMKMC_03346 2e-08
MLCNMKMC_03354 7.8e-08
MLCNMKMC_03359 6.7e-167 ygxA S Nucleotidyltransferase-like
MLCNMKMC_03360 2.1e-55 ygzB S UPF0295 protein
MLCNMKMC_03361 4e-80 perR P Belongs to the Fur family
MLCNMKMC_03362 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
MLCNMKMC_03363 1.4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MLCNMKMC_03364 8.7e-180 ygaE S Membrane
MLCNMKMC_03365 1.8e-301 ygaD V ABC transporter
MLCNMKMC_03366 1.3e-104 ygaC J Belongs to the UPF0374 family
MLCNMKMC_03367 4.9e-48 ygaB S YgaB-like protein
MLCNMKMC_03368 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MLCNMKMC_03369 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_03370 6.9e-36 yfhS
MLCNMKMC_03371 7.8e-212 mutY L A G-specific
MLCNMKMC_03372 5.5e-186 yfhP S membrane-bound metal-dependent
MLCNMKMC_03373 0.0 yfhO S Bacterial membrane protein YfhO
MLCNMKMC_03374 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLCNMKMC_03375 6.7e-172 yfhM S Alpha beta hydrolase
MLCNMKMC_03376 3.5e-51 yfhL S SdpI/YhfL protein family
MLCNMKMC_03377 9.2e-92 batE T Bacterial SH3 domain homologues
MLCNMKMC_03378 4.9e-44 yfhJ S WVELL protein
MLCNMKMC_03379 6.2e-20 sspK S reproduction
MLCNMKMC_03380 1.1e-209 yfhI EGP Major facilitator Superfamily
MLCNMKMC_03382 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MLCNMKMC_03383 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MLCNMKMC_03384 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
MLCNMKMC_03386 2.1e-25 yfhD S YfhD-like protein
MLCNMKMC_03387 3.9e-107 yfhC C nitroreductase
MLCNMKMC_03388 1.8e-167 yfhB 5.3.3.17 S PhzF family
MLCNMKMC_03389 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_03390 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_03391 6.2e-182 yfiY P ABC transporter substrate-binding protein
MLCNMKMC_03392 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLCNMKMC_03393 3.1e-81 yfiV K transcriptional
MLCNMKMC_03394 8.7e-287 yfiU EGP Major facilitator Superfamily
MLCNMKMC_03395 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
MLCNMKMC_03396 5.1e-221 yfiS EGP Major facilitator Superfamily
MLCNMKMC_03397 2e-109 yfiR K Transcriptional regulator
MLCNMKMC_03398 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MLCNMKMC_03399 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLCNMKMC_03400 8.3e-99 padR K transcriptional
MLCNMKMC_03401 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
MLCNMKMC_03402 9.8e-214 V ABC-2 family transporter protein
MLCNMKMC_03403 6.2e-171 V ABC transporter, ATP-binding protein
MLCNMKMC_03404 3.2e-113 KT LuxR family transcriptional regulator
MLCNMKMC_03405 1.1e-214 yxjM T Histidine kinase
MLCNMKMC_03407 1.1e-233 S Oxidoreductase
MLCNMKMC_03408 8.4e-184 G Xylose isomerase
MLCNMKMC_03409 5.3e-262 iolT EGP Major facilitator Superfamily
MLCNMKMC_03410 1.5e-177 K AraC-like ligand binding domain
MLCNMKMC_03411 5.7e-163 yfiE 1.13.11.2 S glyoxalase
MLCNMKMC_03412 9.8e-65 mhqP S DoxX
MLCNMKMC_03413 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLCNMKMC_03414 2.1e-310 yfiB3 V ABC transporter
MLCNMKMC_03415 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLCNMKMC_03416 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
MLCNMKMC_03417 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLCNMKMC_03418 1.1e-44 yfjA S Belongs to the WXG100 family
MLCNMKMC_03419 9.2e-191 yfjB
MLCNMKMC_03420 4.1e-144 yfjC
MLCNMKMC_03421 1.8e-101 yfjD S Family of unknown function (DUF5381)
MLCNMKMC_03422 1.3e-80 S Family of unknown function (DUF5381)
MLCNMKMC_03423 4e-56 yfjF S UPF0060 membrane protein
MLCNMKMC_03424 1.2e-25 sspH S Belongs to the SspH family
MLCNMKMC_03425 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MLCNMKMC_03426 8.6e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLCNMKMC_03427 9.3e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLCNMKMC_03428 3.6e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLCNMKMC_03429 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLCNMKMC_03430 6.6e-29 yfjL
MLCNMKMC_03431 4.4e-28 yfjM S Psort location Cytoplasmic, score
MLCNMKMC_03432 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLCNMKMC_03433 1.6e-39 S YfzA-like protein
MLCNMKMC_03434 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLCNMKMC_03435 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLCNMKMC_03436 1.7e-184 corA P Mediates influx of magnesium ions
MLCNMKMC_03437 1.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MLCNMKMC_03438 1.7e-153 pdaA G deacetylase
MLCNMKMC_03439 1.1e-26 yfjT
MLCNMKMC_03440 5.4e-222 yfkA S YfkB-like domain
MLCNMKMC_03441 6.6e-148 yfkC M Mechanosensitive ion channel
MLCNMKMC_03442 1.2e-146 yfkD S YfkD-like protein
MLCNMKMC_03443 1.8e-182 cax P COG0387 Ca2 H antiporter
MLCNMKMC_03444 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MLCNMKMC_03445 8.2e-143 yihY S Belongs to the UPF0761 family
MLCNMKMC_03446 2.4e-50 yfkI S gas vesicle protein
MLCNMKMC_03447 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLCNMKMC_03448 2.1e-29 yfkK S Belongs to the UPF0435 family
MLCNMKMC_03449 8.9e-207 ydiM EGP Major facilitator Superfamily
MLCNMKMC_03450 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
MLCNMKMC_03451 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MLCNMKMC_03452 1.1e-124 yfkO C nitroreductase
MLCNMKMC_03453 1.8e-133 treR K transcriptional
MLCNMKMC_03454 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MLCNMKMC_03455 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLCNMKMC_03456 1.5e-283 yfkQ EG Spore germination protein
MLCNMKMC_03457 5.1e-207 yfkR S spore germination
MLCNMKMC_03459 1.6e-194 E Spore germination protein
MLCNMKMC_03460 3.2e-256 agcS_1 E Sodium alanine symporter
MLCNMKMC_03461 6e-67 yhdN S Domain of unknown function (DUF1992)
MLCNMKMC_03462 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLCNMKMC_03463 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MLCNMKMC_03464 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MLCNMKMC_03465 2.4e-50 yflH S Protein of unknown function (DUF3243)
MLCNMKMC_03466 4.1e-19 yflI
MLCNMKMC_03467 4e-18 yflJ S Protein of unknown function (DUF2639)
MLCNMKMC_03468 9e-124 yflK S protein conserved in bacteria
MLCNMKMC_03469 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MLCNMKMC_03470 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MLCNMKMC_03471 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MLCNMKMC_03472 1.9e-226 citM C Citrate transporter
MLCNMKMC_03473 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
MLCNMKMC_03474 8.9e-119 citT T response regulator
MLCNMKMC_03475 5.3e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLCNMKMC_03476 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
MLCNMKMC_03477 8.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MLCNMKMC_03478 7.6e-58 yflT S Heat induced stress protein YflT
MLCNMKMC_03479 5e-24 S Protein of unknown function (DUF3212)
MLCNMKMC_03480 6.3e-155 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MLCNMKMC_03481 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_03482 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_03483 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MLCNMKMC_03484 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
MLCNMKMC_03485 2.2e-213 G Major Facilitator Superfamily
MLCNMKMC_03486 1.4e-187 yfmJ S N-terminal domain of oxidoreductase
MLCNMKMC_03487 5.9e-79 yfmK 2.3.1.128 K acetyltransferase
MLCNMKMC_03488 3.8e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MLCNMKMC_03489 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLCNMKMC_03490 1.5e-209 yfmO EGP Major facilitator Superfamily
MLCNMKMC_03491 1.4e-69 yfmP K transcriptional
MLCNMKMC_03492 1.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
MLCNMKMC_03493 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLCNMKMC_03494 1.1e-113 yfmS NT chemotaxis protein
MLCNMKMC_03495 3.7e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLCNMKMC_03496 8.4e-241 yfnA E amino acid
MLCNMKMC_03497 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MLCNMKMC_03498 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
MLCNMKMC_03499 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
MLCNMKMC_03500 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MLCNMKMC_03501 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
MLCNMKMC_03502 1.9e-172 yfnG 4.2.1.45 M dehydratase
MLCNMKMC_03503 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
MLCNMKMC_03504 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLCNMKMC_03505 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MLCNMKMC_03506 3.6e-199 yetN S Protein of unknown function (DUF3900)
MLCNMKMC_03507 7.8e-213 yetM CH FAD binding domain
MLCNMKMC_03508 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_03509 5.4e-159 yetK EG EamA-like transporter family
MLCNMKMC_03510 5.3e-105 yetJ S Belongs to the BI1 family
MLCNMKMC_03511 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MLCNMKMC_03512 1.1e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLCNMKMC_03513 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLCNMKMC_03514 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MLCNMKMC_03515 8.8e-122 yetF S membrane
MLCNMKMC_03516 2.4e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MLCNMKMC_03517 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
MLCNMKMC_03518 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MLCNMKMC_03519 9.6e-291 lplA G Bacterial extracellular solute-binding protein
MLCNMKMC_03520 0.0 yetA
MLCNMKMC_03521 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MLCNMKMC_03522 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
MLCNMKMC_03523 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MLCNMKMC_03524 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MLCNMKMC_03525 5.7e-112 yesV S Protein of unknown function, DUF624
MLCNMKMC_03526 1.5e-126 yesU S Domain of unknown function (DUF1961)
MLCNMKMC_03527 2.6e-129 E GDSL-like Lipase/Acylhydrolase
MLCNMKMC_03528 0.0 yesS K Transcriptional regulator
MLCNMKMC_03529 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MLCNMKMC_03530 5.3e-164 yesQ P Binding-protein-dependent transport system inner membrane component
MLCNMKMC_03531 6.9e-167 yesP G Binding-protein-dependent transport system inner membrane component
MLCNMKMC_03532 3.1e-245 yesO G Bacterial extracellular solute-binding protein
MLCNMKMC_03533 1.8e-201 yesN K helix_turn_helix, arabinose operon control protein
MLCNMKMC_03534 0.0 yesM 2.7.13.3 T Histidine kinase
MLCNMKMC_03535 5e-100 yesL S Protein of unknown function, DUF624
MLCNMKMC_03537 2.3e-101 yesJ K Acetyltransferase (GNAT) family
MLCNMKMC_03538 5.2e-104 cotJC P Spore Coat
MLCNMKMC_03539 1.5e-45 cotJB S CotJB protein
MLCNMKMC_03540 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
MLCNMKMC_03541 2.2e-151 yesF GM NAD(P)H-binding
MLCNMKMC_03542 9.1e-80 yesE S SnoaL-like domain
MLCNMKMC_03543 1.5e-103 dhaR3 K Transcriptional regulator
MLCNMKMC_03545 9.4e-127 yeeN K transcriptional regulatory protein
MLCNMKMC_03547 5.5e-214 S Tetratricopeptide repeat
MLCNMKMC_03548 7e-192 3.4.24.40 CO amine dehydrogenase activity
MLCNMKMC_03549 0.0 L nucleic acid phosphodiester bond hydrolysis
MLCNMKMC_03550 5.5e-83 S Protein of unknown function, DUF600
MLCNMKMC_03551 6.2e-31 S Colicin immunity protein / pyocin immunity protein
MLCNMKMC_03553 1.2e-211 pstS P T5orf172
MLCNMKMC_03554 0.0 yeeB L DEAD-like helicases superfamily
MLCNMKMC_03555 0.0 yeeA V Type II restriction enzyme, methylase subunits
MLCNMKMC_03556 3.2e-53 L Resolvase, N terminal domain
MLCNMKMC_03557 3.2e-98 L Recombinase
MLCNMKMC_03558 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLCNMKMC_03559 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLCNMKMC_03560 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLCNMKMC_03561 4e-156 yerO K Transcriptional regulator
MLCNMKMC_03562 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLCNMKMC_03563 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLCNMKMC_03564 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLCNMKMC_03565 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLCNMKMC_03566 1.6e-123 sapB S MgtC SapB transporter
MLCNMKMC_03567 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
MLCNMKMC_03568 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MLCNMKMC_03569 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLCNMKMC_03570 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MLCNMKMC_03571 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MLCNMKMC_03572 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MLCNMKMC_03573 4.8e-51 yerC S protein conserved in bacteria
MLCNMKMC_03574 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
MLCNMKMC_03575 0.0 yerA 3.5.4.2 F adenine deaminase
MLCNMKMC_03576 2.7e-27 S Protein of unknown function (DUF2892)
MLCNMKMC_03577 6.4e-227 yjeH E Amino acid permease
MLCNMKMC_03578 3.5e-73 K helix_turn_helix ASNC type
MLCNMKMC_03579 6.3e-235 purD 6.3.4.13 F Belongs to the GARS family
MLCNMKMC_03580 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MLCNMKMC_03581 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLCNMKMC_03582 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MLCNMKMC_03583 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLCNMKMC_03584 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLCNMKMC_03585 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLCNMKMC_03586 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLCNMKMC_03587 3.7e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MLCNMKMC_03588 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLCNMKMC_03589 1.6e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLCNMKMC_03590 7.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLCNMKMC_03591 8e-28 yebG S NETI protein
MLCNMKMC_03592 4e-93 yebE S UPF0316 protein
MLCNMKMC_03594 1.9e-115 yebC M Membrane
MLCNMKMC_03595 7.8e-212 pbuG S permease
MLCNMKMC_03596 9.8e-256 S Domain of unknown function (DUF4179)
MLCNMKMC_03597 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_03598 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MLCNMKMC_03599 0.0 yebA E COG1305 Transglutaminase-like enzymes
MLCNMKMC_03600 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MLCNMKMC_03601 1.5e-175 yeaC S COG0714 MoxR-like ATPases
MLCNMKMC_03602 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLCNMKMC_03603 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MLCNMKMC_03604 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MLCNMKMC_03605 8e-177 yeaA S Protein of unknown function (DUF4003)
MLCNMKMC_03606 8.4e-156 ydjP I Alpha/beta hydrolase family
MLCNMKMC_03607 1.4e-34 ydjO S Cold-inducible protein YdjO
MLCNMKMC_03609 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
MLCNMKMC_03610 4.5e-64 ydjM M Lytic transglycolase
MLCNMKMC_03611 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MLCNMKMC_03612 2.7e-258 iolT EGP Major facilitator Superfamily
MLCNMKMC_03613 1.5e-194 S Ion transport 2 domain protein
MLCNMKMC_03614 2.6e-148 ydjI S virion core protein (lumpy skin disease virus)
MLCNMKMC_03615 2.1e-132 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MLCNMKMC_03616 4.1e-176 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLCNMKMC_03617 8.7e-114 pspA KT Phage shock protein A
MLCNMKMC_03618 1.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MLCNMKMC_03619 2.1e-252 gutA G MFS/sugar transport protein
MLCNMKMC_03620 1.8e-198 gutB 1.1.1.14 E Dehydrogenase
MLCNMKMC_03621 0.0 K NB-ARC domain
MLCNMKMC_03622 1.3e-150 ydjC S Abhydrolase domain containing 18
MLCNMKMC_03623 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLCNMKMC_03624 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLCNMKMC_03625 7.9e-129 ydiL S CAAX protease self-immunity
MLCNMKMC_03626 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MLCNMKMC_03627 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLCNMKMC_03628 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLCNMKMC_03629 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLCNMKMC_03630 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MLCNMKMC_03631 0.0 ydiF S ABC transporter
MLCNMKMC_03632 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLCNMKMC_03633 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLCNMKMC_03634 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MLCNMKMC_03635 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MLCNMKMC_03636 7.1e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MLCNMKMC_03639 7.8e-08
MLCNMKMC_03643 4.6e-157 ydhU P Catalase
MLCNMKMC_03644 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MLCNMKMC_03645 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLCNMKMC_03646 1.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MLCNMKMC_03647 1.1e-132 ydhQ K UTRA
MLCNMKMC_03648 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLCNMKMC_03649 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLCNMKMC_03650 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLCNMKMC_03651 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLCNMKMC_03652 4.6e-200 pbuE EGP Major facilitator Superfamily
MLCNMKMC_03653 2.5e-98 ydhK M Protein of unknown function (DUF1541)
MLCNMKMC_03654 5.7e-132 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MLCNMKMC_03655 6.7e-33 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MLCNMKMC_03656 7.5e-80 K Acetyltransferase (GNAT) domain
MLCNMKMC_03658 1.6e-66 frataxin S Domain of unknown function (DU1801)
MLCNMKMC_03659 4.4e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MLCNMKMC_03660 1.6e-123
MLCNMKMC_03661 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLCNMKMC_03662 1.4e-242 ydhD M Glycosyl hydrolase
MLCNMKMC_03663 6.5e-122 ydhC K FCD
MLCNMKMC_03664 1.2e-121 ydhB S membrane transporter protein
MLCNMKMC_03665 7.4e-209 tcaB EGP Major facilitator Superfamily
MLCNMKMC_03666 7.1e-69 ydgJ K Winged helix DNA-binding domain
MLCNMKMC_03667 2.3e-113 drgA C nitroreductase
MLCNMKMC_03668 0.0 ydgH S drug exporters of the RND superfamily
MLCNMKMC_03669 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_03670 8.7e-90 dinB S DinB family
MLCNMKMC_03671 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MLCNMKMC_03672 7e-303 expZ S ABC transporter
MLCNMKMC_03673 9e-86 yycN 2.3.1.128 K Acetyltransferase
MLCNMKMC_03674 2.4e-51 S DoxX-like family
MLCNMKMC_03675 1.7e-97 K Bacterial regulatory proteins, tetR family
MLCNMKMC_03676 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MLCNMKMC_03677 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MLCNMKMC_03678 1.1e-74 cotP O Belongs to the small heat shock protein (HSP20) family
MLCNMKMC_03679 7.6e-121 ydfS S Protein of unknown function (DUF421)
MLCNMKMC_03680 4.4e-118 ydfR S Protein of unknown function (DUF421)
MLCNMKMC_03682 6.3e-29
MLCNMKMC_03683 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MLCNMKMC_03684 1.5e-53 traF CO Thioredoxin
MLCNMKMC_03685 8.8e-63 mhqP S DoxX
MLCNMKMC_03686 3.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MLCNMKMC_03687 2.6e-109 ydfN C nitroreductase
MLCNMKMC_03688 4.5e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLCNMKMC_03689 3.2e-147 K Bacterial transcription activator, effector binding domain
MLCNMKMC_03690 5.9e-118 S Protein of unknown function (DUF554)
MLCNMKMC_03691 1.9e-177 S Alpha/beta hydrolase family
MLCNMKMC_03692 0.0 ydfJ S drug exporters of the RND superfamily
MLCNMKMC_03693 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLCNMKMC_03694 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
MLCNMKMC_03696 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLCNMKMC_03697 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MLCNMKMC_03698 5.9e-117 ydfE S Flavin reductase like domain
MLCNMKMC_03699 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLCNMKMC_03700 1e-162 ydfC EG EamA-like transporter family
MLCNMKMC_03701 7.2e-149 ydfB J GNAT acetyltransferase
MLCNMKMC_03702 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLCNMKMC_03703 1.8e-56 arsR K transcriptional
MLCNMKMC_03704 2.5e-104 ydeS K Transcriptional regulator
MLCNMKMC_03705 1.5e-185 ydeR EGP Major facilitator Superfamily
MLCNMKMC_03706 1.7e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
MLCNMKMC_03707 1.8e-68 ydeP K Transcriptional regulator
MLCNMKMC_03708 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MLCNMKMC_03709 5.7e-55 K HxlR-like helix-turn-helix
MLCNMKMC_03710 1.8e-104 ydeN S Serine hydrolase
MLCNMKMC_03711 1.3e-72 maoC I N-terminal half of MaoC dehydratase
MLCNMKMC_03712 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLCNMKMC_03713 2e-152 ydeK EG -transporter
MLCNMKMC_03714 3.4e-84 K Transcriptional regulator C-terminal region
MLCNMKMC_03715 1.8e-14 ptsH G PTS HPr component phosphorylation site
MLCNMKMC_03716 1.1e-31 S SNARE associated Golgi protein
MLCNMKMC_03717 1.3e-109
MLCNMKMC_03718 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MLCNMKMC_03719 2.7e-45 ydeH
MLCNMKMC_03720 1.8e-216 ydeG EGP Major facilitator superfamily
MLCNMKMC_03721 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLCNMKMC_03722 1.4e-164 ydeE K AraC family transcriptional regulator
MLCNMKMC_03723 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLCNMKMC_03724 1.4e-164 rhaS5 K AraC-like ligand binding domain
MLCNMKMC_03725 4.4e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLCNMKMC_03726 1.5e-77 carD K Transcription factor
MLCNMKMC_03727 8.7e-30 cspL K Cold shock
MLCNMKMC_03728 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MLCNMKMC_03732 9.6e-40
MLCNMKMC_03733 1.7e-32 K Helix-turn-helix XRE-family like proteins
MLCNMKMC_03734 5.7e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLCNMKMC_03735 8.5e-45
MLCNMKMC_03736 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
MLCNMKMC_03744 1.6e-84 ydcK S Belongs to the SprT family
MLCNMKMC_03745 0.0 yhgF K COG2183 Transcriptional accessory protein
MLCNMKMC_03746 1e-75 ydcH K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_03747 1.5e-82 ydcG S EVE domain
MLCNMKMC_03751 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MLCNMKMC_03752 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLCNMKMC_03753 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MLCNMKMC_03754 5.9e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
MLCNMKMC_03755 9.3e-189 rsbU 3.1.3.3 KT phosphatase
MLCNMKMC_03756 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MLCNMKMC_03757 5.2e-57 rsbS T antagonist
MLCNMKMC_03758 3.7e-143 rsbR T Positive regulator of sigma-B
MLCNMKMC_03759 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MLCNMKMC_03760 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MLCNMKMC_03761 5.6e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLCNMKMC_03762 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MLCNMKMC_03763 2.3e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLCNMKMC_03764 1.3e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MLCNMKMC_03765 7.3e-259 ydbT S Membrane
MLCNMKMC_03766 2.1e-82 ydbS S Bacterial PH domain
MLCNMKMC_03767 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLCNMKMC_03768 4.8e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLCNMKMC_03769 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MLCNMKMC_03770 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLCNMKMC_03771 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLCNMKMC_03772 2.2e-07 S Fur-regulated basic protein A
MLCNMKMC_03773 1.1e-18 S Fur-regulated basic protein B
MLCNMKMC_03774 4.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MLCNMKMC_03775 2.7e-52 ydbL
MLCNMKMC_03776 1.2e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLCNMKMC_03777 4.7e-171 ydbJ V ABC transporter, ATP-binding protein
MLCNMKMC_03778 4.4e-181 ydbI S AI-2E family transporter
MLCNMKMC_03779 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLCNMKMC_03780 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
MLCNMKMC_03781 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLCNMKMC_03782 3.5e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MLCNMKMC_03783 1e-153 ydbD P Catalase
MLCNMKMC_03784 1.8e-62 ydbC S Domain of unknown function (DUF4937
MLCNMKMC_03785 8.9e-59 ydbB G Cupin domain
MLCNMKMC_03787 1.1e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MLCNMKMC_03788 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MLCNMKMC_03790 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MLCNMKMC_03791 2.1e-39
MLCNMKMC_03792 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MLCNMKMC_03793 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MLCNMKMC_03794 0.0 ydaO E amino acid
MLCNMKMC_03795 0.0 ydaN S Bacterial cellulose synthase subunit
MLCNMKMC_03796 4.5e-233 ydaM M Glycosyl transferase family group 2
MLCNMKMC_03797 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MLCNMKMC_03798 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
MLCNMKMC_03799 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLCNMKMC_03800 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLCNMKMC_03801 2.5e-74 lrpC K Transcriptional regulator
MLCNMKMC_03802 3.3e-46 ydzA EGP Major facilitator Superfamily
MLCNMKMC_03803 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MLCNMKMC_03804 6.8e-77 ydaG 1.4.3.5 S general stress protein
MLCNMKMC_03805 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLCNMKMC_03806 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MLCNMKMC_03807 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_03808 9e-99 ydaC Q Methyltransferase domain
MLCNMKMC_03809 1.8e-292 ydaB IQ acyl-CoA ligase
MLCNMKMC_03810 0.0 mtlR K transcriptional regulator, MtlR
MLCNMKMC_03811 2.8e-176 ydhF S Oxidoreductase
MLCNMKMC_03812 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MLCNMKMC_03813 1.4e-49 yczJ S biosynthesis
MLCNMKMC_03815 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
MLCNMKMC_03816 1.2e-132 kipR K Transcriptional regulator
MLCNMKMC_03817 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MLCNMKMC_03818 8e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MLCNMKMC_03819 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
MLCNMKMC_03820 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MLCNMKMC_03821 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
MLCNMKMC_03822 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MLCNMKMC_03824 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MLCNMKMC_03825 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MLCNMKMC_03826 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLCNMKMC_03827 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLCNMKMC_03828 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MLCNMKMC_03829 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MLCNMKMC_03830 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MLCNMKMC_03831 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MLCNMKMC_03832 7.3e-56
MLCNMKMC_03833 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MLCNMKMC_03834 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MLCNMKMC_03835 2.9e-100 ycnI S protein conserved in bacteria
MLCNMKMC_03836 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLCNMKMC_03837 1.8e-148 glcU U Glucose uptake
MLCNMKMC_03838 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLCNMKMC_03839 2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLCNMKMC_03840 5.6e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLCNMKMC_03841 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MLCNMKMC_03842 1.6e-45 ycnE S Monooxygenase
MLCNMKMC_03843 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MLCNMKMC_03844 7.1e-153 ycnC K Transcriptional regulator
MLCNMKMC_03845 1.4e-251 ycnB EGP Major facilitator Superfamily
MLCNMKMC_03846 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MLCNMKMC_03847 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MLCNMKMC_03848 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_03849 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_03850 2e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
MLCNMKMC_03854 5.8e-78 S aspartate phosphatase
MLCNMKMC_03855 3.7e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MLCNMKMC_03856 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_03857 4e-201 yclI V ABC transporter (permease) YclI
MLCNMKMC_03858 5.6e-121 yclH P ABC transporter
MLCNMKMC_03859 2.4e-198 gerKB F Spore germination protein
MLCNMKMC_03860 9.1e-231 gerKC S spore germination
MLCNMKMC_03861 6.4e-280 gerKA EG Spore germination protein
MLCNMKMC_03863 1e-307 yclG M Pectate lyase superfamily protein
MLCNMKMC_03864 3.6e-266 dtpT E amino acid peptide transporter
MLCNMKMC_03865 5.4e-158 yclE 3.4.11.5 S Alpha beta hydrolase
MLCNMKMC_03866 2.5e-80 yclD
MLCNMKMC_03867 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
MLCNMKMC_03868 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MLCNMKMC_03869 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MLCNMKMC_03870 3.5e-160 bsdA K LysR substrate binding domain
MLCNMKMC_03871 6.4e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MLCNMKMC_03872 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MLCNMKMC_03873 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLCNMKMC_03874 4.4e-115 yczE S membrane
MLCNMKMC_03875 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MLCNMKMC_03876 4.4e-255 ycxD K GntR family transcriptional regulator
MLCNMKMC_03877 7.4e-164 ycxC EG EamA-like transporter family
MLCNMKMC_03878 4.9e-91 S YcxB-like protein
MLCNMKMC_03879 4.2e-228 EGP Major Facilitator Superfamily
MLCNMKMC_03880 5.7e-140 srfAD Q thioesterase
MLCNMKMC_03881 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MLCNMKMC_03882 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_03883 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLCNMKMC_03884 3.7e-63 hxlR K transcriptional
MLCNMKMC_03885 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MLCNMKMC_03886 2.5e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MLCNMKMC_03887 1.5e-186 tlpC 2.7.13.3 NT chemotaxis protein
MLCNMKMC_03888 3e-70 nucA M Deoxyribonuclease NucA/NucB
MLCNMKMC_03889 6.5e-69 nin S Competence protein J (ComJ)
MLCNMKMC_03890 8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLCNMKMC_03891 7.8e-52 yckD S Protein of unknown function (DUF2680)
MLCNMKMC_03892 6.2e-76 yckC S membrane
MLCNMKMC_03895 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MLCNMKMC_03896 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MLCNMKMC_03897 1.3e-226 yciC S GTPases (G3E family)
MLCNMKMC_03898 5.5e-109 yciB M ErfK YbiS YcfS YnhG
MLCNMKMC_03899 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MLCNMKMC_03900 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
MLCNMKMC_03901 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MLCNMKMC_03902 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLCNMKMC_03903 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLCNMKMC_03904 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MLCNMKMC_03905 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MLCNMKMC_03906 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MLCNMKMC_03907 5.7e-163 I alpha/beta hydrolase fold
MLCNMKMC_03908 1.2e-139 ycgR S permeases
MLCNMKMC_03909 2.6e-147 ycgQ S membrane
MLCNMKMC_03910 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MLCNMKMC_03911 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLCNMKMC_03912 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLCNMKMC_03913 5.1e-170 ycgM E Proline dehydrogenase
MLCNMKMC_03914 2.9e-145 ycgL S Predicted nucleotidyltransferase
MLCNMKMC_03915 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MLCNMKMC_03916 2.2e-179 oxyR3 K LysR substrate binding domain
MLCNMKMC_03917 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
MLCNMKMC_03918 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLCNMKMC_03919 2.5e-109 tmrB S AAA domain
MLCNMKMC_03920 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLCNMKMC_03921 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MLCNMKMC_03922 1.2e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MLCNMKMC_03923 8.4e-150 yqcI S YqcI/YcgG family
MLCNMKMC_03924 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MLCNMKMC_03925 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
MLCNMKMC_03926 3.9e-263 mdr EGP Major facilitator Superfamily
MLCNMKMC_03927 3.3e-289 lctP C L-lactate permease
MLCNMKMC_03928 1.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MLCNMKMC_03929 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MLCNMKMC_03930 4.1e-81 ycgB
MLCNMKMC_03931 8.7e-257 ycgA S Membrane
MLCNMKMC_03932 1.2e-219 amhX S amidohydrolase
MLCNMKMC_03933 5.3e-164 opuAC E glycine betaine
MLCNMKMC_03934 1.3e-127 opuAB P glycine betaine
MLCNMKMC_03935 5.1e-229 proV 3.6.3.32 E glycine betaine
MLCNMKMC_03936 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MLCNMKMC_03937 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
MLCNMKMC_03938 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
MLCNMKMC_03939 2e-192 yceH P Belongs to the TelA family
MLCNMKMC_03940 0.0 yceG S Putative component of 'biosynthetic module'
MLCNMKMC_03941 6.3e-137 terC P Protein of unknown function (DUF475)
MLCNMKMC_03942 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MLCNMKMC_03943 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MLCNMKMC_03944 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MLCNMKMC_03945 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLCNMKMC_03946 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLCNMKMC_03947 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLCNMKMC_03948 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
MLCNMKMC_03949 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MLCNMKMC_03950 4.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
MLCNMKMC_03951 5.5e-174 S response regulator aspartate phosphatase
MLCNMKMC_03952 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
MLCNMKMC_03953 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_03954 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_03955 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MLCNMKMC_03956 1.6e-174 yccK C Aldo keto reductase
MLCNMKMC_03957 4.5e-203 natB CP ABC-2 family transporter protein
MLCNMKMC_03958 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MLCNMKMC_03959 1.2e-126 lytR_2 T LytTr DNA-binding domain
MLCNMKMC_03960 2e-161 2.7.13.3 T GHKL domain
MLCNMKMC_03961 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
MLCNMKMC_03962 2e-59 S RDD family
MLCNMKMC_03963 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLCNMKMC_03964 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MLCNMKMC_03965 4.8e-102 yxaF K Transcriptional regulator
MLCNMKMC_03966 5.8e-229 lmrB EGP the major facilitator superfamily
MLCNMKMC_03967 6.2e-210 ycbU E Selenocysteine lyase
MLCNMKMC_03968 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MLCNMKMC_03969 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLCNMKMC_03970 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLCNMKMC_03971 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MLCNMKMC_03972 2.5e-135 ycbR T vWA found in TerF C terminus
MLCNMKMC_03973 1.3e-78 sleB 3.5.1.28 M Cell wall
MLCNMKMC_03974 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MLCNMKMC_03975 2.1e-115 S ABC-2 family transporter protein
MLCNMKMC_03976 4.8e-168 ycbN V ABC transporter, ATP-binding protein
MLCNMKMC_03977 2.4e-170 T PhoQ Sensor
MLCNMKMC_03978 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLCNMKMC_03979 7.3e-172 eamA1 EG spore germination
MLCNMKMC_03980 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MLCNMKMC_03981 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
MLCNMKMC_03982 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
MLCNMKMC_03983 1.5e-124 ycbG K FCD
MLCNMKMC_03984 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLCNMKMC_03985 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MLCNMKMC_03986 1.3e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLCNMKMC_03987 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MLCNMKMC_03988 9e-170 glnL T Regulator
MLCNMKMC_03989 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
MLCNMKMC_03990 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
MLCNMKMC_03991 2.3e-257 agcS E Sodium alanine symporter
MLCNMKMC_03992 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MLCNMKMC_03993 4.5e-258 mmuP E amino acid
MLCNMKMC_03994 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MLCNMKMC_03996 4.9e-128 K UTRA
MLCNMKMC_03997 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLCNMKMC_03998 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLCNMKMC_03999 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLCNMKMC_04000 3.9e-192 yceA S Belongs to the UPF0176 family
MLCNMKMC_04001 6.7e-167 ybfP K Transcriptional regulator
MLCNMKMC_04002 3.4e-255 S Erythromycin esterase
MLCNMKMC_04003 4.6e-45 ybfN
MLCNMKMC_04004 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MLCNMKMC_04005 2.7e-85 ybfM S SNARE associated Golgi protein
MLCNMKMC_04006 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLCNMKMC_04007 2.1e-168 S Alpha/beta hydrolase family
MLCNMKMC_04009 7.6e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MLCNMKMC_04010 2.1e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLCNMKMC_04011 1.1e-144 msmR K AraC-like ligand binding domain
MLCNMKMC_04012 2e-161 ybfH EG EamA-like transporter family
MLCNMKMC_04013 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
MLCNMKMC_04015 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
MLCNMKMC_04016 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
MLCNMKMC_04017 2.9e-35 S Protein of unknown function (DUF2651)
MLCNMKMC_04018 7.3e-258 glpT G -transporter
MLCNMKMC_04019 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLCNMKMC_04020 1.8e-290 ybeC E amino acid
MLCNMKMC_04021 4.9e-41 ybyB
MLCNMKMC_04022 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MLCNMKMC_04023 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
MLCNMKMC_04024 4.9e-30 ybxH S Family of unknown function (DUF5370)
MLCNMKMC_04025 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
MLCNMKMC_04026 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MLCNMKMC_04027 1.6e-216 ybdO S Domain of unknown function (DUF4885)
MLCNMKMC_04028 7.7e-152 ybdN
MLCNMKMC_04029 1.6e-140 KLT Protein tyrosine kinase
MLCNMKMC_04031 1.8e-173 T His Kinase A (phospho-acceptor) domain
MLCNMKMC_04032 1.5e-123 T Transcriptional regulatory protein, C terminal
MLCNMKMC_04033 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLCNMKMC_04034 9.6e-79 txn CO Thioredoxin-like
MLCNMKMC_04035 7.8e-91 C HEAT repeats
MLCNMKMC_04036 4e-248 skfF S ABC transporter
MLCNMKMC_04037 1.9e-135 skfE V ABC transporter
MLCNMKMC_04038 1.6e-277 V CAAX protease self-immunity
MLCNMKMC_04039 9.1e-239 J 4Fe-4S single cluster domain
MLCNMKMC_04041 2e-203 ybcL EGP Major facilitator Superfamily
MLCNMKMC_04042 5.1e-50 ybzH K Helix-turn-helix domain
MLCNMKMC_04043 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MLCNMKMC_04044 3.9e-47
MLCNMKMC_04045 3.7e-96 can 4.2.1.1 P carbonic anhydrase
MLCNMKMC_04046 0.0 ybcC S Belongs to the UPF0753 family
MLCNMKMC_04047 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLCNMKMC_04048 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLCNMKMC_04049 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
MLCNMKMC_04050 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLCNMKMC_04051 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLCNMKMC_04052 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLCNMKMC_04053 3e-225 ybbR S protein conserved in bacteria
MLCNMKMC_04054 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLCNMKMC_04055 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MLCNMKMC_04056 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MLCNMKMC_04062 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MLCNMKMC_04063 6.4e-87 ybbJ J acetyltransferase
MLCNMKMC_04064 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLCNMKMC_04065 1.1e-150 ybbH K transcriptional
MLCNMKMC_04066 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLCNMKMC_04067 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MLCNMKMC_04068 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MLCNMKMC_04069 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
MLCNMKMC_04070 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MLCNMKMC_04071 7.2e-167 feuA P Iron-uptake system-binding protein
MLCNMKMC_04072 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_04073 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLCNMKMC_04074 2.2e-142 ybbA S Putative esterase
MLCNMKMC_04075 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
MLCNMKMC_04077 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MLCNMKMC_04078 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
MLCNMKMC_04079 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MLCNMKMC_04080 1.2e-84 gerD
MLCNMKMC_04081 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MLCNMKMC_04082 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLCNMKMC_04083 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MLCNMKMC_04084 2.4e-144 ybaJ Q Methyltransferase domain
MLCNMKMC_04085 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MLCNMKMC_04086 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLCNMKMC_04087 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLCNMKMC_04088 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLCNMKMC_04089 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLCNMKMC_04090 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLCNMKMC_04091 3.6e-58 rplQ J Ribosomal protein L17
MLCNMKMC_04092 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLCNMKMC_04093 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLCNMKMC_04094 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLCNMKMC_04095 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MLCNMKMC_04096 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLCNMKMC_04097 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MLCNMKMC_04098 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLCNMKMC_04099 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLCNMKMC_04100 1.8e-72 rplO J binds to the 23S rRNA
MLCNMKMC_04101 1.9e-23 rpmD J Ribosomal protein L30
MLCNMKMC_04102 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLCNMKMC_04103 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLCNMKMC_04104 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLCNMKMC_04105 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLCNMKMC_04106 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLCNMKMC_04107 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLCNMKMC_04108 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLCNMKMC_04109 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLCNMKMC_04110 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLCNMKMC_04111 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MLCNMKMC_04112 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLCNMKMC_04113 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLCNMKMC_04114 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLCNMKMC_04115 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLCNMKMC_04116 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLCNMKMC_04117 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLCNMKMC_04118 3e-105 rplD J Forms part of the polypeptide exit tunnel
MLCNMKMC_04119 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLCNMKMC_04120 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MLCNMKMC_04121 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MLCNMKMC_04122 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLCNMKMC_04123 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLCNMKMC_04124 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLCNMKMC_04125 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLCNMKMC_04126 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MLCNMKMC_04127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLCNMKMC_04128 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLCNMKMC_04129 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MLCNMKMC_04130 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLCNMKMC_04131 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLCNMKMC_04132 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLCNMKMC_04133 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLCNMKMC_04134 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MLCNMKMC_04135 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLCNMKMC_04136 4.4e-115 sigH K Belongs to the sigma-70 factor family
MLCNMKMC_04137 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MLCNMKMC_04138 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLCNMKMC_04139 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLCNMKMC_04140 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLCNMKMC_04141 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MLCNMKMC_04142 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLCNMKMC_04143 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MLCNMKMC_04144 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MLCNMKMC_04145 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MLCNMKMC_04146 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MLCNMKMC_04147 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLCNMKMC_04148 0.0 clpC O Belongs to the ClpA ClpB family
MLCNMKMC_04149 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MLCNMKMC_04150 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MLCNMKMC_04151 2.9e-76 ctsR K Belongs to the CtsR family
MLCNMKMC_04155 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MLCNMKMC_04156 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLCNMKMC_04157 4.1e-30 yazB K transcriptional
MLCNMKMC_04158 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLCNMKMC_04159 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLCNMKMC_04160 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLCNMKMC_04161 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MLCNMKMC_04162 2.1e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MLCNMKMC_04163 7e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLCNMKMC_04164 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLCNMKMC_04165 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MLCNMKMC_04166 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLCNMKMC_04167 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MLCNMKMC_04168 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLCNMKMC_04169 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MLCNMKMC_04170 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLCNMKMC_04171 6.1e-180 KLT serine threonine protein kinase
MLCNMKMC_04172 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MLCNMKMC_04173 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MLCNMKMC_04176 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MLCNMKMC_04177 1.1e-44 divIC D Septum formation initiator
MLCNMKMC_04178 4.3e-107 yabQ S spore cortex biosynthesis protein
MLCNMKMC_04179 1.5e-49 yabP S Sporulation protein YabP
MLCNMKMC_04180 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MLCNMKMC_04181 1.9e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MLCNMKMC_04182 1.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLCNMKMC_04183 1.5e-92 spoVT K stage V sporulation protein
MLCNMKMC_04184 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLCNMKMC_04185 2.4e-39 yabK S Peptide ABC transporter permease
MLCNMKMC_04186 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLCNMKMC_04187 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MLCNMKMC_04188 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLCNMKMC_04189 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLCNMKMC_04190 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MLCNMKMC_04191 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MLCNMKMC_04192 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MLCNMKMC_04193 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLCNMKMC_04194 8.3e-27 sspF S DNA topological change
MLCNMKMC_04195 7.8e-39 veg S protein conserved in bacteria
MLCNMKMC_04196 1.8e-135 yabG S peptidase
MLCNMKMC_04197 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLCNMKMC_04198 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLCNMKMC_04199 4.5e-167 rpfB GH23 T protein conserved in bacteria
MLCNMKMC_04200 1.2e-143 tatD L hydrolase, TatD
MLCNMKMC_04201 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLCNMKMC_04202 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MLCNMKMC_04203 3.5e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLCNMKMC_04204 1.5e-49 yazA L endonuclease containing a URI domain
MLCNMKMC_04205 7.2e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MLCNMKMC_04206 4.8e-31 yabA L Involved in initiation control of chromosome replication
MLCNMKMC_04207 6.1e-146 yaaT S stage 0 sporulation protein
MLCNMKMC_04208 1.1e-181 holB 2.7.7.7 L DNA polymerase III
MLCNMKMC_04209 1.5e-71 yaaR S protein conserved in bacteria
MLCNMKMC_04210 2.2e-54 yaaQ S protein conserved in bacteria
MLCNMKMC_04211 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLCNMKMC_04212 7.3e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MLCNMKMC_04213 1.3e-202 yaaN P Belongs to the TelA family
MLCNMKMC_04214 6.8e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MLCNMKMC_04215 3.4e-31 csfB S Inhibitor of sigma-G Gin
MLCNMKMC_04216 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MLCNMKMC_04217 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MLCNMKMC_04218 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLCNMKMC_04219 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLCNMKMC_04220 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLCNMKMC_04221 4.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLCNMKMC_04222 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
MLCNMKMC_04223 5.1e-208 yaaH M Glycoside Hydrolase Family
MLCNMKMC_04224 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MLCNMKMC_04225 2.4e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MLCNMKMC_04226 1.3e-09
MLCNMKMC_04227 8.9e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLCNMKMC_04228 1.8e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MLCNMKMC_04229 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MLCNMKMC_04230 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MLCNMKMC_04231 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MLCNMKMC_04232 1e-181 yaaC S YaaC-like Protein
MLCNMKMC_04233 3.4e-39 S COG NOG14552 non supervised orthologous group

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)