ORF_ID e_value Gene_name EC_number CAZy COGs Description
CLHAPNMH_00001 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CLHAPNMH_00002 2.6e-42
CLHAPNMH_00003 1.6e-299 ytgP S Polysaccharide biosynthesis protein
CLHAPNMH_00004 5e-63 3.2.1.23 S Domain of unknown function DUF302
CLHAPNMH_00005 2.4e-156 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLHAPNMH_00006 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
CLHAPNMH_00007 3.3e-86 uspA T Belongs to the universal stress protein A family
CLHAPNMH_00008 1e-254 S Putative peptidoglycan binding domain
CLHAPNMH_00009 7.7e-160 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CLHAPNMH_00010 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
CLHAPNMH_00011 6.8e-110
CLHAPNMH_00012 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
CLHAPNMH_00013 9e-119 S CAAX protease self-immunity
CLHAPNMH_00014 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLHAPNMH_00015 8.4e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
CLHAPNMH_00016 8.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
CLHAPNMH_00017 3.7e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CLHAPNMH_00018 2e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
CLHAPNMH_00019 2.4e-201 folP 2.5.1.15 H dihydropteroate synthase
CLHAPNMH_00021 1.7e-36
CLHAPNMH_00023 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CLHAPNMH_00024 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CLHAPNMH_00025 9.8e-56 yheA S Belongs to the UPF0342 family
CLHAPNMH_00026 3.7e-179 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
CLHAPNMH_00027 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CLHAPNMH_00029 1.4e-77 hit FG histidine triad
CLHAPNMH_00030 2.3e-133 ecsA V ABC transporter, ATP-binding protein
CLHAPNMH_00031 2.9e-210 ecsB U ABC transporter
CLHAPNMH_00032 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CLHAPNMH_00033 1.2e-57 ytzB S Small secreted protein
CLHAPNMH_00034 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CLHAPNMH_00035 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CLHAPNMH_00036 4.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CLHAPNMH_00037 1.8e-114 ybhL S Belongs to the BI1 family
CLHAPNMH_00038 2.9e-139 aroD S Serine hydrolase (FSH1)
CLHAPNMH_00039 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLHAPNMH_00040 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CLHAPNMH_00041 3.5e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CLHAPNMH_00042 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLHAPNMH_00043 1e-251 dnaB L replication initiation and membrane attachment
CLHAPNMH_00044 2.5e-172 dnaI L Primosomal protein DnaI
CLHAPNMH_00045 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLHAPNMH_00046 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CLHAPNMH_00047 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLHAPNMH_00048 1.9e-19 yoaK S Protein of unknown function (DUF1275)
CLHAPNMH_00049 2.2e-96 yqeG S HAD phosphatase, family IIIA
CLHAPNMH_00050 2.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
CLHAPNMH_00051 2.6e-49 yhbY J RNA-binding protein
CLHAPNMH_00052 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLHAPNMH_00053 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
CLHAPNMH_00054 1.8e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CLHAPNMH_00055 8.3e-142 yqeM Q Methyltransferase
CLHAPNMH_00056 5.5e-214 ylbM S Belongs to the UPF0348 family
CLHAPNMH_00057 7.8e-97 yceD S Uncharacterized ACR, COG1399
CLHAPNMH_00058 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CLHAPNMH_00059 5.6e-121 K response regulator
CLHAPNMH_00060 9e-281 arlS 2.7.13.3 T Histidine kinase
CLHAPNMH_00061 1.6e-233 V MatE
CLHAPNMH_00062 5.1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CLHAPNMH_00063 1e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CLHAPNMH_00064 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CLHAPNMH_00065 1.5e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLHAPNMH_00066 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
CLHAPNMH_00067 7.8e-60 yodB K Transcriptional regulator, HxlR family
CLHAPNMH_00068 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLHAPNMH_00069 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CLHAPNMH_00070 3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
CLHAPNMH_00071 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CLHAPNMH_00072 0.0 S membrane
CLHAPNMH_00073 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
CLHAPNMH_00074 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CLHAPNMH_00075 3.5e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLHAPNMH_00076 1.1e-116 gluP 3.4.21.105 S Peptidase, S54 family
CLHAPNMH_00077 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
CLHAPNMH_00078 1.2e-180 glk 2.7.1.2 G Glucokinase
CLHAPNMH_00079 1.5e-71 yqhL P Rhodanese-like protein
CLHAPNMH_00080 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
CLHAPNMH_00081 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLHAPNMH_00082 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
CLHAPNMH_00083 4.7e-13
CLHAPNMH_00084 2.4e-148
CLHAPNMH_00085 5.1e-176
CLHAPNMH_00086 6.6e-93 dut S Protein conserved in bacteria
CLHAPNMH_00088 3.7e-114 K Transcriptional regulator
CLHAPNMH_00089 8.9e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
CLHAPNMH_00090 9e-53 ysxB J Cysteine protease Prp
CLHAPNMH_00091 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CLHAPNMH_00092 6.8e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CLHAPNMH_00093 4.1e-72 yqhY S Asp23 family, cell envelope-related function
CLHAPNMH_00094 4e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLHAPNMH_00095 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLHAPNMH_00096 3e-257 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CLHAPNMH_00097 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CLHAPNMH_00098 6.2e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CLHAPNMH_00099 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CLHAPNMH_00100 6.2e-76 argR K Regulates arginine biosynthesis genes
CLHAPNMH_00101 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
CLHAPNMH_00102 1.6e-14
CLHAPNMH_00103 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CLHAPNMH_00104 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CLHAPNMH_00105 9.2e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLHAPNMH_00106 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLHAPNMH_00107 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLHAPNMH_00108 4.5e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLHAPNMH_00109 2.2e-131 stp 3.1.3.16 T phosphatase
CLHAPNMH_00110 0.0 KLT serine threonine protein kinase
CLHAPNMH_00111 6.3e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CLHAPNMH_00112 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CLHAPNMH_00113 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
CLHAPNMH_00114 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CLHAPNMH_00115 3.6e-58 asp S Asp23 family, cell envelope-related function
CLHAPNMH_00116 2.9e-304 yloV S DAK2 domain fusion protein YloV
CLHAPNMH_00117 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLHAPNMH_00118 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CLHAPNMH_00119 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLHAPNMH_00120 5.2e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CLHAPNMH_00121 0.0 smc D Required for chromosome condensation and partitioning
CLHAPNMH_00122 3.4e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CLHAPNMH_00123 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CLHAPNMH_00124 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLHAPNMH_00126 7.8e-95
CLHAPNMH_00127 2.6e-129 K Transcriptional regulatory protein, C-terminal domain protein
CLHAPNMH_00128 5.1e-159 pstS P Phosphate
CLHAPNMH_00129 5.6e-153 pstC P probably responsible for the translocation of the substrate across the membrane
CLHAPNMH_00130 9.4e-153 pstA P Phosphate transport system permease protein PstA
CLHAPNMH_00131 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CLHAPNMH_00132 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
CLHAPNMH_00133 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CLHAPNMH_00134 5e-38 ylqC S Belongs to the UPF0109 family
CLHAPNMH_00135 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLHAPNMH_00136 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CLHAPNMH_00137 2.2e-260 yfnA E Amino Acid
CLHAPNMH_00138 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CLHAPNMH_00140 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
CLHAPNMH_00141 3.3e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CLHAPNMH_00142 1.9e-178 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLHAPNMH_00143 2.9e-262 lysC 2.7.2.4 E Belongs to the aspartokinase family
CLHAPNMH_00144 1.3e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CLHAPNMH_00145 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CLHAPNMH_00146 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CLHAPNMH_00147 3.5e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLHAPNMH_00148 2.3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CLHAPNMH_00149 1.7e-218 patA 2.6.1.1 E Aminotransferase
CLHAPNMH_00150 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLHAPNMH_00151 1.5e-226 ktrB P Potassium uptake protein
CLHAPNMH_00152 4.4e-118 ktrA P domain protein
CLHAPNMH_00153 1.7e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
CLHAPNMH_00154 1.9e-155 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLHAPNMH_00155 1.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CLHAPNMH_00157 0.0 dnaE 2.7.7.7 L DNA polymerase
CLHAPNMH_00158 8.3e-268 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CLHAPNMH_00159 1.6e-168 cvfB S S1 domain
CLHAPNMH_00160 1.1e-158 xerD D recombinase XerD
CLHAPNMH_00161 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLHAPNMH_00162 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CLHAPNMH_00163 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLHAPNMH_00164 2.8e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CLHAPNMH_00165 3.7e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CLHAPNMH_00166 6e-199 ypbB 5.1.3.1 S Helix-turn-helix domain
CLHAPNMH_00167 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
CLHAPNMH_00168 9.7e-31 M Lysin motif
CLHAPNMH_00169 2e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CLHAPNMH_00170 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
CLHAPNMH_00171 3.7e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CLHAPNMH_00172 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CLHAPNMH_00173 1.8e-234 S Tetratricopeptide repeat protein
CLHAPNMH_00174 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
CLHAPNMH_00175 2.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CLHAPNMH_00176 0.0 yfmR S ABC transporter, ATP-binding protein
CLHAPNMH_00177 6.8e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLHAPNMH_00178 8.7e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLHAPNMH_00179 1.2e-109 hlyIII S protein, hemolysin III
CLHAPNMH_00180 6.8e-153 DegV S EDD domain protein, DegV family
CLHAPNMH_00181 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
CLHAPNMH_00182 3.2e-107 cat S Bacterial transferase hexapeptide (six repeats)
CLHAPNMH_00183 1.1e-167 ypmR E lipolytic protein G-D-S-L family
CLHAPNMH_00184 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
CLHAPNMH_00185 3.1e-36 yozE S Belongs to the UPF0346 family
CLHAPNMH_00186 1.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CLHAPNMH_00187 1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLHAPNMH_00188 8.1e-165 dprA LU DNA protecting protein DprA
CLHAPNMH_00189 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLHAPNMH_00190 1.6e-154 D DNA integration
CLHAPNMH_00191 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
CLHAPNMH_00192 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CLHAPNMH_00193 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CLHAPNMH_00194 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CLHAPNMH_00195 5.2e-95 S Protein of unknown function (DUF1440)
CLHAPNMH_00196 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
CLHAPNMH_00197 2.3e-71 yqkB S Belongs to the HesB IscA family
CLHAPNMH_00198 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CLHAPNMH_00199 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
CLHAPNMH_00200 5.9e-82 yebR 1.8.4.14 T GAF domain-containing protein
CLHAPNMH_00201 1.8e-243 U Belongs to the purine-cytosine permease (2.A.39) family
CLHAPNMH_00202 8e-243 codA 3.5.4.1 F cytosine deaminase
CLHAPNMH_00203 0.0 oppD EP Psort location Cytoplasmic, score
CLHAPNMH_00205 3.1e-256 rarA L recombination factor protein RarA
CLHAPNMH_00206 1.7e-117 S Protein of unknown function (DUF554)
CLHAPNMH_00207 1.8e-243 yhjX P Major Facilitator Superfamily
CLHAPNMH_00208 2.1e-77 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
CLHAPNMH_00209 2.6e-120 S Fic/DOC family
CLHAPNMH_00210 3.4e-92 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
CLHAPNMH_00211 1.6e-122 EGP Sugar (and other) transporter
CLHAPNMH_00212 9.8e-92 EGP Sugar (and other) transporter
CLHAPNMH_00213 1.9e-51 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
CLHAPNMH_00214 4.7e-86 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
CLHAPNMH_00215 1.6e-213 2.6.1.1 E Aminotransferase
CLHAPNMH_00218 7.5e-34 S Phage minor capsid protein 2
CLHAPNMH_00219 2.8e-71 S Phage minor capsid protein 2
CLHAPNMH_00220 7.4e-163 I alpha/beta hydrolase fold
CLHAPNMH_00221 1e-93 K Acetyltransferase (GNAT) domain
CLHAPNMH_00223 3.4e-161 S DUF218 domain
CLHAPNMH_00224 5.1e-167 1.1.1.346 C Aldo keto reductase
CLHAPNMH_00225 2.6e-80 hmpT S ECF-type riboflavin transporter, S component
CLHAPNMH_00226 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
CLHAPNMH_00227 9.6e-236 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
CLHAPNMH_00228 4e-62 ywkB S Membrane transport protein
CLHAPNMH_00229 3.2e-203 xerS L Belongs to the 'phage' integrase family
CLHAPNMH_00230 2.1e-179 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CLHAPNMH_00231 2.7e-224 4.4.1.8 E Aminotransferase, class I
CLHAPNMH_00232 6.3e-196 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
CLHAPNMH_00233 1.4e-86 C Zinc-binding dehydrogenase
CLHAPNMH_00234 1.2e-101 proW P ABC transporter, permease protein
CLHAPNMH_00235 1.6e-140 proV E ABC transporter, ATP-binding protein
CLHAPNMH_00236 7.9e-109 proWZ P ABC transporter permease
CLHAPNMH_00237 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
CLHAPNMH_00238 4e-75 K Transcriptional regulator
CLHAPNMH_00239 4.2e-74 O OsmC-like protein
CLHAPNMH_00240 2.8e-75 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
CLHAPNMH_00241 2.2e-25 C Flavodoxin
CLHAPNMH_00242 1.9e-65 GM NmrA-like family
CLHAPNMH_00243 2.5e-30 GM NmrA-like family
CLHAPNMH_00244 3.3e-45 K transcriptional regulator
CLHAPNMH_00245 3.9e-107 L Integrase
CLHAPNMH_00246 1.8e-159 yicL EG EamA-like transporter family
CLHAPNMH_00247 3.2e-49 C Flavodoxin
CLHAPNMH_00248 1.4e-27 IQ oxidoreductase activity
CLHAPNMH_00249 5.3e-58 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CLHAPNMH_00251 3.8e-29 ybbM S Uncharacterised protein family (UPF0014)
CLHAPNMH_00253 7.4e-146 sua5 2.7.7.87 J Telomere recombination
CLHAPNMH_00254 3.3e-106 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLHAPNMH_00255 9.3e-280 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLHAPNMH_00256 1.1e-195 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CLHAPNMH_00257 1.7e-238 ydjE EGP Major facilitator Superfamily
CLHAPNMH_00258 4.4e-127 yocS S Transporter
CLHAPNMH_00259 1e-27 XK27_02560 S Pfam:DUF59
CLHAPNMH_00260 3.4e-260 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CLHAPNMH_00261 3e-111 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CLHAPNMH_00262 5.8e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLHAPNMH_00263 1.7e-226 mtnE 2.6.1.83 E Aminotransferase
CLHAPNMH_00264 2.3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
CLHAPNMH_00265 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CLHAPNMH_00266 2.6e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CLHAPNMH_00267 3.6e-162 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLHAPNMH_00268 9.2e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLHAPNMH_00269 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
CLHAPNMH_00270 4.1e-53 KT PspC domain protein
CLHAPNMH_00271 1.3e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLHAPNMH_00272 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CLHAPNMH_00273 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLHAPNMH_00274 8e-128 comFC S Competence protein
CLHAPNMH_00275 7.7e-252 comFA L Helicase C-terminal domain protein
CLHAPNMH_00276 2.4e-113 yvyE 3.4.13.9 S YigZ family
CLHAPNMH_00277 1.4e-37
CLHAPNMH_00278 0.0 ydaO E amino acid
CLHAPNMH_00279 1.4e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CLHAPNMH_00280 4.3e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLHAPNMH_00281 2.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CLHAPNMH_00282 0.0 uup S ABC transporter, ATP-binding protein
CLHAPNMH_00283 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CLHAPNMH_00284 9.7e-92 bioY S BioY family
CLHAPNMH_00285 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CLHAPNMH_00286 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
CLHAPNMH_00287 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLHAPNMH_00288 4.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
CLHAPNMH_00289 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CLHAPNMH_00290 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CLHAPNMH_00291 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CLHAPNMH_00292 7.8e-129 IQ reductase
CLHAPNMH_00293 7.4e-172 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CLHAPNMH_00294 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLHAPNMH_00295 2.8e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLHAPNMH_00296 8.7e-75 marR K Transcriptional regulator, MarR family
CLHAPNMH_00297 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CLHAPNMH_00299 3.4e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLHAPNMH_00300 2.5e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
CLHAPNMH_00301 2.2e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
CLHAPNMH_00302 1.9e-214 arcT 2.6.1.1 E Aminotransferase
CLHAPNMH_00303 2.3e-220 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
CLHAPNMH_00304 7e-259 E Arginine ornithine antiporter
CLHAPNMH_00305 8.2e-240 arcA 3.5.3.6 E Arginine
CLHAPNMH_00306 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
CLHAPNMH_00307 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLHAPNMH_00308 4.2e-150 KT YcbB domain
CLHAPNMH_00309 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CLHAPNMH_00310 2.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CLHAPNMH_00311 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLHAPNMH_00312 7.4e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CLHAPNMH_00313 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
CLHAPNMH_00314 2.1e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLHAPNMH_00315 1.5e-55 yabA L Involved in initiation control of chromosome replication
CLHAPNMH_00316 1.9e-192 holB 2.7.7.7 L DNA polymerase III
CLHAPNMH_00317 4e-53 yaaQ S Cyclic-di-AMP receptor
CLHAPNMH_00318 3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLHAPNMH_00319 2.4e-21 S Protein of unknown function (DUF2508)
CLHAPNMH_00320 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLHAPNMH_00321 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLHAPNMH_00322 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLHAPNMH_00324 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CLHAPNMH_00325 2e-35 nrdH O Glutaredoxin
CLHAPNMH_00326 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLHAPNMH_00327 7.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLHAPNMH_00328 1.3e-246 brnQ U Component of the transport system for branched-chain amino acids
CLHAPNMH_00329 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CLHAPNMH_00330 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLHAPNMH_00331 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CLHAPNMH_00332 4.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
CLHAPNMH_00333 1.1e-272 cydA 1.10.3.14 C ubiquinol oxidase
CLHAPNMH_00334 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CLHAPNMH_00335 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLHAPNMH_00336 4.6e-244 steT E amino acid
CLHAPNMH_00337 7.4e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CLHAPNMH_00338 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLHAPNMH_00339 4.5e-97 nusG K Participates in transcription elongation, termination and antitermination
CLHAPNMH_00340 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CLHAPNMH_00341 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CLHAPNMH_00342 1.1e-104 sigH K Belongs to the sigma-70 factor family
CLHAPNMH_00343 2e-135 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLHAPNMH_00344 1.6e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CLHAPNMH_00345 1e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CLHAPNMH_00346 2.3e-99 ywlG S Belongs to the UPF0340 family
CLHAPNMH_00347 9.6e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLHAPNMH_00348 7.2e-206 yacL S domain protein
CLHAPNMH_00349 1.2e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLHAPNMH_00350 4.9e-96 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
CLHAPNMH_00351 3.5e-54 HA62_12640 S GCN5-related N-acetyl-transferase
CLHAPNMH_00352 2.3e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLHAPNMH_00353 1.1e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
CLHAPNMH_00354 4e-264 pepC 3.4.22.40 E Peptidase C1-like family
CLHAPNMH_00355 4.8e-165 I alpha/beta hydrolase fold
CLHAPNMH_00356 6.1e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLHAPNMH_00357 5e-168 mleP2 S Sodium Bile acid symporter family
CLHAPNMH_00358 4e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
CLHAPNMH_00359 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
CLHAPNMH_00361 1.4e-80 ydcK S Belongs to the SprT family
CLHAPNMH_00362 0.0 yhgF K Tex-like protein N-terminal domain protein
CLHAPNMH_00363 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CLHAPNMH_00364 2.5e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLHAPNMH_00365 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
CLHAPNMH_00366 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CLHAPNMH_00367 9.6e-115
CLHAPNMH_00370 7.8e-165 yjjH S Calcineurin-like phosphoesterase
CLHAPNMH_00371 2e-256 dtpT U amino acid peptide transporter
CLHAPNMH_00372 2.8e-169 D nuclear chromosome segregation
CLHAPNMH_00373 1e-103 dedA S SNARE-like domain protein
CLHAPNMH_00374 9.8e-25 S Protein of unknown function (DUF1461)
CLHAPNMH_00375 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CLHAPNMH_00376 1.2e-97 yutD S Protein of unknown function (DUF1027)
CLHAPNMH_00377 5.3e-110 S Calcineurin-like phosphoesterase
CLHAPNMH_00378 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLHAPNMH_00379 1e-159 ytxK 2.1.1.72 L N-6 DNA Methylase
CLHAPNMH_00381 3.8e-14
CLHAPNMH_00383 1e-15 NU general secretion pathway protein
CLHAPNMH_00384 1.1e-47 comGC U competence protein ComGC
CLHAPNMH_00385 7.1e-160 comGB NU type II secretion system
CLHAPNMH_00386 2.7e-177 comGA NU Type II IV secretion system protein
CLHAPNMH_00387 1.3e-86 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
CLHAPNMH_00388 2.5e-97 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
CLHAPNMH_00389 9.2e-83 mltD CBM50 M PFAM NLP P60 protein
CLHAPNMH_00390 3.7e-134 yebC K Transcriptional regulatory protein
CLHAPNMH_00391 3.6e-85
CLHAPNMH_00392 2.2e-185 ccpA K catabolite control protein A
CLHAPNMH_00393 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CLHAPNMH_00394 4.9e-70
CLHAPNMH_00395 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CLHAPNMH_00396 4e-156 ykuT M mechanosensitive ion channel
CLHAPNMH_00397 4.9e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
CLHAPNMH_00398 1.4e-95 S Phosphoesterase
CLHAPNMH_00399 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLHAPNMH_00400 1.2e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CLHAPNMH_00401 1.6e-94 yslB S Protein of unknown function (DUF2507)
CLHAPNMH_00402 1.2e-225 clcA_2 P Chloride transporter, ClC family
CLHAPNMH_00403 1e-53 trxA O Belongs to the thioredoxin family
CLHAPNMH_00404 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CLHAPNMH_00405 4.7e-91 cvpA S Colicin V production protein
CLHAPNMH_00406 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLHAPNMH_00407 5.7e-33 yrzB S Belongs to the UPF0473 family
CLHAPNMH_00408 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLHAPNMH_00409 1.2e-42 yrzL S Belongs to the UPF0297 family
CLHAPNMH_00410 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLHAPNMH_00411 4.2e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CLHAPNMH_00412 6.8e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
CLHAPNMH_00413 5.5e-42 yajC U Preprotein translocase
CLHAPNMH_00414 2.2e-176 2.4.2.29 F queuine tRNA-ribosyltransferase activity
CLHAPNMH_00415 1.1e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CLHAPNMH_00416 1.1e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CLHAPNMH_00417 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLHAPNMH_00418 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLHAPNMH_00419 1e-202 rny S Endoribonuclease that initiates mRNA decay
CLHAPNMH_00420 2.2e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLHAPNMH_00421 6e-230 cinA 3.5.1.42 S Belongs to the CinA family
CLHAPNMH_00422 1.1e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLHAPNMH_00423 1.8e-96 ymfM S Helix-turn-helix domain
CLHAPNMH_00424 1.7e-251 ymfH S Peptidase M16
CLHAPNMH_00425 4.3e-231 ymfF S Peptidase M16 inactive domain protein
CLHAPNMH_00426 2.4e-161 aatB ET ABC transporter substrate-binding protein
CLHAPNMH_00427 2.2e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CLHAPNMH_00428 1.4e-108 glnP P ABC transporter permease
CLHAPNMH_00429 4.3e-92 mreD M rod shape-determining protein MreD
CLHAPNMH_00430 3.7e-146 mreC M Involved in formation and maintenance of cell shape
CLHAPNMH_00431 1.9e-181 mreB D cell shape determining protein MreB
CLHAPNMH_00432 2.5e-115 radC L DNA repair protein
CLHAPNMH_00433 7.2e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CLHAPNMH_00434 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CLHAPNMH_00435 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLHAPNMH_00438 8.4e-24 S zinc-ribbon domain
CLHAPNMH_00439 2e-39
CLHAPNMH_00440 1.2e-35 M LysM domain
CLHAPNMH_00441 6.1e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CLHAPNMH_00442 2.5e-210 EG GntP family permease
CLHAPNMH_00443 1.1e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLHAPNMH_00444 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
CLHAPNMH_00445 2.2e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CLHAPNMH_00446 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLHAPNMH_00448 2.1e-25 S YjcQ protein
CLHAPNMH_00449 2.3e-148 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLHAPNMH_00450 5.3e-133 S Membrane
CLHAPNMH_00451 1.3e-75 4.4.1.5 E Glyoxalase
CLHAPNMH_00452 4.5e-85 yueI S Protein of unknown function (DUF1694)
CLHAPNMH_00453 2.2e-235 rarA L recombination factor protein RarA
CLHAPNMH_00455 2.3e-81 usp6 T universal stress protein
CLHAPNMH_00456 1.4e-150 2.3.1.19 K Helix-turn-helix XRE-family like proteins
CLHAPNMH_00457 3.6e-114 yjbH Q Thioredoxin
CLHAPNMH_00458 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
CLHAPNMH_00459 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLHAPNMH_00460 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
CLHAPNMH_00461 4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CLHAPNMH_00462 1.3e-162 rrmA 2.1.1.187 H Methyltransferase
CLHAPNMH_00463 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CLHAPNMH_00464 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CLHAPNMH_00465 1.2e-07 S Protein of unknown function (DUF4044)
CLHAPNMH_00466 5.8e-58
CLHAPNMH_00467 1.3e-78 mraZ K Belongs to the MraZ family
CLHAPNMH_00468 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CLHAPNMH_00469 7e-09 ftsL D Cell division protein FtsL
CLHAPNMH_00470 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CLHAPNMH_00471 1.2e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLHAPNMH_00472 9.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLHAPNMH_00473 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLHAPNMH_00474 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CLHAPNMH_00475 3.2e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CLHAPNMH_00476 9e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLHAPNMH_00477 2.7e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CLHAPNMH_00478 6.8e-41 yggT S YGGT family
CLHAPNMH_00479 1.3e-145 ylmH S S4 domain protein
CLHAPNMH_00480 4.8e-112 divIVA D DivIVA domain protein
CLHAPNMH_00482 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLHAPNMH_00483 1.2e-32 cspB K Cold shock protein
CLHAPNMH_00484 2.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
CLHAPNMH_00486 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLHAPNMH_00487 3.4e-58 XK27_04120 S Putative amino acid metabolism
CLHAPNMH_00488 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CLHAPNMH_00489 2.3e-306 S amidohydrolase
CLHAPNMH_00490 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CLHAPNMH_00491 4.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
CLHAPNMH_00492 7.1e-124 S Repeat protein
CLHAPNMH_00493 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CLHAPNMH_00494 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLHAPNMH_00495 4.2e-74 spx4 1.20.4.1 P ArsC family
CLHAPNMH_00496 9e-189 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
CLHAPNMH_00497 2.2e-31 ykzG S Belongs to the UPF0356 family
CLHAPNMH_00498 1.5e-74
CLHAPNMH_00499 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CLHAPNMH_00500 2.4e-49 yktA S Belongs to the UPF0223 family
CLHAPNMH_00501 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CLHAPNMH_00502 0.0 typA T GTP-binding protein TypA
CLHAPNMH_00503 2.8e-216 ftsW D Belongs to the SEDS family
CLHAPNMH_00504 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
CLHAPNMH_00505 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
CLHAPNMH_00506 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLHAPNMH_00507 5.6e-197 ylbL T Belongs to the peptidase S16 family
CLHAPNMH_00508 1.3e-90 comEA L Competence protein ComEA
CLHAPNMH_00509 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
CLHAPNMH_00510 0.0 comEC S Competence protein ComEC
CLHAPNMH_00511 9.2e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
CLHAPNMH_00512 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
CLHAPNMH_00513 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLHAPNMH_00514 1.5e-261 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CLHAPNMH_00515 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLHAPNMH_00516 1.1e-164 S Tetratricopeptide repeat
CLHAPNMH_00517 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLHAPNMH_00518 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CLHAPNMH_00519 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLHAPNMH_00520 2.3e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
CLHAPNMH_00521 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
CLHAPNMH_00523 3.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CLHAPNMH_00524 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CLHAPNMH_00525 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLHAPNMH_00526 4.1e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CLHAPNMH_00527 4.3e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CLHAPNMH_00528 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CLHAPNMH_00529 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLHAPNMH_00530 5.6e-62 S Domain of unknown function (DUF4440)
CLHAPNMH_00531 8.6e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLHAPNMH_00532 3.3e-152 tesE Q hydratase
CLHAPNMH_00533 0.0 FbpA K Fibronectin-binding protein
CLHAPNMH_00534 3.2e-161 degV S EDD domain protein, DegV family
CLHAPNMH_00535 1.3e-97
CLHAPNMH_00536 4.8e-134 S Belongs to the UPF0246 family
CLHAPNMH_00537 9.5e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CLHAPNMH_00538 5.3e-113 ylbE GM NAD(P)H-binding
CLHAPNMH_00539 3.5e-99 K Acetyltransferase (GNAT) domain
CLHAPNMH_00540 5.2e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CLHAPNMH_00541 1.2e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CLHAPNMH_00542 5.5e-286 thrC 4.2.3.1 E Threonine synthase
CLHAPNMH_00543 1.8e-122 azlC E azaleucine resistance protein AzlC
CLHAPNMH_00544 2.8e-54 azlD E Branched-chain amino acid transport
CLHAPNMH_00545 4.8e-183 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CLHAPNMH_00546 1.3e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
CLHAPNMH_00547 1.5e-204 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CLHAPNMH_00548 4.1e-259 lpdA 1.8.1.4 C Dehydrogenase
CLHAPNMH_00549 2.3e-195 lplA 6.3.1.20 H Lipoate-protein ligase
CLHAPNMH_00550 1.5e-216 E GDSL-like Lipase/Acylhydrolase family
CLHAPNMH_00551 2.3e-33 K LysR substrate binding domain protein
CLHAPNMH_00552 4.6e-47 K LysR substrate binding domain protein
CLHAPNMH_00553 7.3e-212 naiP EGP Major facilitator Superfamily
CLHAPNMH_00554 1.2e-250 yhdP S Transporter associated domain
CLHAPNMH_00555 3.4e-201 mdtG EGP Major facilitator Superfamily
CLHAPNMH_00556 2.5e-160 EGP Major facilitator Superfamily
CLHAPNMH_00557 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
CLHAPNMH_00558 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLHAPNMH_00559 1.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CLHAPNMH_00560 2.4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
CLHAPNMH_00561 1.4e-275 pipD E Dipeptidase
CLHAPNMH_00562 0.0 yjbQ P TrkA C-terminal domain protein
CLHAPNMH_00563 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CLHAPNMH_00564 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLHAPNMH_00566 0.0 kup P Transport of potassium into the cell
CLHAPNMH_00567 1.6e-49
CLHAPNMH_00568 0.0 S Bacterial membrane protein YfhO
CLHAPNMH_00570 2.7e-237 lmrB EGP Major facilitator Superfamily
CLHAPNMH_00571 6.7e-156 S Alpha beta hydrolase
CLHAPNMH_00572 1.2e-157 1.6.5.2 GM NAD(P)H-binding
CLHAPNMH_00573 1.7e-153 S Sucrose-6F-phosphate phosphohydrolase
CLHAPNMH_00576 4.8e-242 dtpT U amino acid peptide transporter
CLHAPNMH_00578 6.4e-213 ydiN G Major Facilitator Superfamily
CLHAPNMH_00579 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
CLHAPNMH_00580 6.7e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLHAPNMH_00581 5e-104
CLHAPNMH_00582 4.2e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CLHAPNMH_00583 1.3e-196 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CLHAPNMH_00584 8.7e-90 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLHAPNMH_00585 6e-216 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
CLHAPNMH_00586 2.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLHAPNMH_00587 2.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CLHAPNMH_00588 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
CLHAPNMH_00589 6.7e-23 S Virus attachment protein p12 family
CLHAPNMH_00590 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CLHAPNMH_00591 2e-32 feoA P FeoA domain
CLHAPNMH_00592 5.5e-144 sufC O FeS assembly ATPase SufC
CLHAPNMH_00593 5.8e-244 sufD O FeS assembly protein SufD
CLHAPNMH_00594 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLHAPNMH_00595 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
CLHAPNMH_00596 4.2e-272 sufB O assembly protein SufB
CLHAPNMH_00597 7.8e-178 fecB P Periplasmic binding protein
CLHAPNMH_00598 3e-126 yfeJ 6.3.5.2 F glutamine amidotransferase
CLHAPNMH_00599 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CLHAPNMH_00600 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
CLHAPNMH_00601 8e-196 6.3.1.20 H Lipoate-protein ligase
CLHAPNMH_00602 1.6e-174 lytH 3.5.1.28 M Ami_3
CLHAPNMH_00603 1.4e-169 yniA G Phosphotransferase enzyme family
CLHAPNMH_00604 1.4e-50 L Helix-turn-helix domain
CLHAPNMH_00605 6.2e-85 L hmm pf00665
CLHAPNMH_00606 4.6e-174 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
CLHAPNMH_00607 4.7e-247 mmuP E amino acid
CLHAPNMH_00608 2.2e-159 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CLHAPNMH_00609 3.1e-212 hom1 1.1.1.3 E Homoserine dehydrogenase
CLHAPNMH_00610 1.5e-166 L PFAM Integrase catalytic region
CLHAPNMH_00611 6.4e-96 L Helix-turn-helix domain
CLHAPNMH_00612 8.5e-78 IQ KR domain
CLHAPNMH_00613 4.4e-25 IQ KR domain
CLHAPNMH_00614 9.1e-153 cjaA ET ABC transporter substrate-binding protein
CLHAPNMH_00615 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CLHAPNMH_00616 5.7e-94 P ABC transporter permease
CLHAPNMH_00617 5.4e-113 papP P ABC transporter, permease protein
CLHAPNMH_00619 1.5e-90 yxeQ S MmgE/PrpD family
CLHAPNMH_00620 1.1e-171 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
CLHAPNMH_00621 1.7e-146 3.5.1.47 E Peptidase dimerisation domain
CLHAPNMH_00622 3.4e-78 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
CLHAPNMH_00623 1.7e-70 yxeN U ABC transporter, permease protein
CLHAPNMH_00624 1.3e-46 yxeL K acetyltransferase
CLHAPNMH_00625 3.1e-67 yxeM ET Bacterial periplasmic substrate-binding proteins
CLHAPNMH_00626 2.8e-210 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
CLHAPNMH_00627 2.3e-218 metC1 2.5.1.48, 4.4.1.8 E cystathionine
CLHAPNMH_00628 1.3e-84 slyA K Transcriptional regulator
CLHAPNMH_00629 1.6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CLHAPNMH_00630 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLHAPNMH_00631 4.4e-58
CLHAPNMH_00632 6.8e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CLHAPNMH_00633 1.8e-181 prmA J Ribosomal protein L11 methyltransferase
CLHAPNMH_00634 1.2e-54
CLHAPNMH_00636 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CLHAPNMH_00637 1.6e-219 L Probable transposase
CLHAPNMH_00638 4.7e-96 S integral membrane protein
CLHAPNMH_00639 7.7e-13 aes I esterase lipase
CLHAPNMH_00640 8.4e-37 S CRISPR-associated protein (Cas_Csn2)
CLHAPNMH_00641 4.9e-35 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLHAPNMH_00642 1.9e-92 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLHAPNMH_00643 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CLHAPNMH_00644 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLHAPNMH_00645 2.5e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CLHAPNMH_00646 9.4e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CLHAPNMH_00647 1.1e-113 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CLHAPNMH_00648 1.5e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CLHAPNMH_00649 1.2e-68 psiE S Phosphate-starvation-inducible E
CLHAPNMH_00650 5.9e-39 V CAAX protease self-immunity
CLHAPNMH_00651 2.1e-215 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
CLHAPNMH_00652 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
CLHAPNMH_00653 3.5e-76 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
CLHAPNMH_00654 2.3e-106 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
CLHAPNMH_00655 3.6e-09 K LysR substrate binding domain
CLHAPNMH_00656 4.7e-09 S ChrR Cupin-like domain
CLHAPNMH_00657 1.5e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLHAPNMH_00658 1.9e-158 P Belongs to the nlpA lipoprotein family
CLHAPNMH_00659 8.4e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLHAPNMH_00660 3.2e-116 S Protein of unknown function (DUF554)
CLHAPNMH_00661 4.4e-101 P Cadmium resistance transporter
CLHAPNMH_00662 3.8e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLHAPNMH_00663 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CLHAPNMH_00664 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLHAPNMH_00665 1.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
CLHAPNMH_00666 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLHAPNMH_00667 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CLHAPNMH_00668 3.4e-92 K transcriptional regulator
CLHAPNMH_00669 3.9e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
CLHAPNMH_00670 8.7e-188 ybhR V ABC transporter
CLHAPNMH_00671 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
CLHAPNMH_00672 2.6e-281 glpQ 3.1.4.46 C phosphodiesterase
CLHAPNMH_00673 9.8e-163 yvgN C Aldo keto reductase
CLHAPNMH_00674 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CLHAPNMH_00675 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CLHAPNMH_00676 5.7e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLHAPNMH_00677 0.0 clpL O associated with various cellular activities
CLHAPNMH_00678 1e-34
CLHAPNMH_00679 8.5e-218 patA 2.6.1.1 E Aminotransferase
CLHAPNMH_00680 3.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLHAPNMH_00681 3.2e-183 D Alpha beta
CLHAPNMH_00682 2.4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CLHAPNMH_00683 2.3e-111 ysdA CP transmembrane transport
CLHAPNMH_00684 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
CLHAPNMH_00685 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
CLHAPNMH_00686 1.6e-249 malT G Major Facilitator
CLHAPNMH_00687 1.6e-174 malR K Transcriptional regulator, LacI family
CLHAPNMH_00688 1.3e-70 K Transcriptional regulator
CLHAPNMH_00689 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLHAPNMH_00690 1.5e-207 htrA 3.4.21.107 O serine protease
CLHAPNMH_00691 5.1e-153 vicX 3.1.26.11 S domain protein
CLHAPNMH_00692 2e-141 yycI S YycH protein
CLHAPNMH_00693 1.6e-238 yycH S YycH protein
CLHAPNMH_00694 0.0 vicK 2.7.13.3 T Histidine kinase
CLHAPNMH_00695 6.8e-130 K response regulator
CLHAPNMH_00698 6.3e-50
CLHAPNMH_00699 2.3e-207 lmrP E Major Facilitator Superfamily
CLHAPNMH_00700 3.7e-236 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CLHAPNMH_00701 1.2e-74 rplI J Binds to the 23S rRNA
CLHAPNMH_00702 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CLHAPNMH_00703 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLHAPNMH_00704 4.2e-90 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CLHAPNMH_00705 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
CLHAPNMH_00706 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLHAPNMH_00707 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLHAPNMH_00708 7.4e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLHAPNMH_00709 1.7e-34 yaaA S S4 domain protein YaaA
CLHAPNMH_00710 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CLHAPNMH_00711 5.2e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLHAPNMH_00713 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
CLHAPNMH_00714 9.3e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CLHAPNMH_00715 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CLHAPNMH_00716 1.8e-153 jag S R3H domain protein
CLHAPNMH_00717 1.1e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLHAPNMH_00718 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CLHAPNMH_00719 1.4e-294 xylB 2.7.1.12, 2.7.1.17 G Xylulose kinase
CLHAPNMH_00720 6.4e-270 xylA 5.3.1.5 G Belongs to the xylose isomerase family
CLHAPNMH_00721 9.5e-253 xylT EGP Major facilitator Superfamily
CLHAPNMH_00722 2.7e-216 xylR GK ROK family
CLHAPNMH_00723 5.9e-152 glcU U sugar transport
CLHAPNMH_00724 1.3e-250 yclK 2.7.13.3 T Histidine kinase
CLHAPNMH_00725 1.7e-131 K response regulator
CLHAPNMH_00727 1.6e-57 S Domain of unknown function (DUF956)
CLHAPNMH_00728 3e-170 manN G system, mannose fructose sorbose family IID component
CLHAPNMH_00729 2.7e-122 manY G PTS system
CLHAPNMH_00730 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
CLHAPNMH_00731 2.3e-181 yfeX P Peroxidase
CLHAPNMH_00732 6.5e-90 racA K Domain of unknown function (DUF1836)
CLHAPNMH_00733 5.1e-148 yitS S EDD domain protein, DegV family
CLHAPNMH_00734 2.9e-131 manA 5.3.1.8 G mannose-6-phosphate isomerase
CLHAPNMH_00735 9.6e-169 K LysR substrate binding domain
CLHAPNMH_00736 2.7e-159 MA20_14895 S Conserved hypothetical protein 698
CLHAPNMH_00737 2.4e-75 lytE M Lysin motif
CLHAPNMH_00738 1.2e-149 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
CLHAPNMH_00739 3.2e-211 oatA I Acyltransferase
CLHAPNMH_00740 1.5e-52
CLHAPNMH_00741 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CLHAPNMH_00742 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLHAPNMH_00743 7e-116 ybbR S YbbR-like protein
CLHAPNMH_00744 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLHAPNMH_00745 5.7e-166 murB 1.3.1.98 M Cell wall formation
CLHAPNMH_00746 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
CLHAPNMH_00747 3.3e-89 K Acetyltransferase (GNAT) domain
CLHAPNMH_00748 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
CLHAPNMH_00749 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CLHAPNMH_00750 2.4e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLHAPNMH_00751 5.5e-109 yxjI
CLHAPNMH_00752 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CLHAPNMH_00753 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CLHAPNMH_00754 4.5e-33 secG U Preprotein translocase
CLHAPNMH_00755 8.4e-290 clcA P chloride
CLHAPNMH_00756 1.5e-253 yifK E Amino acid permease
CLHAPNMH_00757 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CLHAPNMH_00758 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CLHAPNMH_00759 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CLHAPNMH_00760 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CLHAPNMH_00761 1e-15
CLHAPNMH_00762 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
CLHAPNMH_00768 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CLHAPNMH_00769 7.6e-180 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLHAPNMH_00770 8.9e-27 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
CLHAPNMH_00771 1.6e-104 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
CLHAPNMH_00772 4.3e-41 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
CLHAPNMH_00773 4.2e-27 S Protein of unknown function (DUF2877)
CLHAPNMH_00774 2.2e-120 arcC 2.7.2.2 E Amino acid kinase family
CLHAPNMH_00775 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
CLHAPNMH_00776 1.1e-123 C nitroreductase
CLHAPNMH_00777 4.6e-137 E GDSL-like Lipase/Acylhydrolase family
CLHAPNMH_00778 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
CLHAPNMH_00779 5.6e-197 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
CLHAPNMH_00780 0.0 pepN 3.4.11.2 E aminopeptidase
CLHAPNMH_00781 1.1e-15 tlpA2 L Transposase IS200 like
CLHAPNMH_00782 2e-204 L transposase, IS605 OrfB family
CLHAPNMH_00783 4e-60 K Transcriptional regulator
CLHAPNMH_00784 1.1e-23 phaG GT1 I carboxylic ester hydrolase activity
CLHAPNMH_00785 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CLHAPNMH_00787 9.6e-155 metQ_4 P Belongs to the nlpA lipoprotein family
CLHAPNMH_00788 4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CLHAPNMH_00789 0.0 helD 3.6.4.12 L DNA helicase
CLHAPNMH_00790 6.6e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CLHAPNMH_00791 6.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CLHAPNMH_00792 6.5e-187
CLHAPNMH_00793 4.4e-129 cobB K SIR2 family
CLHAPNMH_00794 2e-211 norA EGP Major facilitator Superfamily
CLHAPNMH_00795 3.1e-161 yunF F Protein of unknown function DUF72
CLHAPNMH_00796 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLHAPNMH_00797 1.8e-147 tatD L hydrolase, TatD family
CLHAPNMH_00798 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CLHAPNMH_00799 9.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CLHAPNMH_00800 1.3e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CLHAPNMH_00801 4e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
CLHAPNMH_00802 5.4e-95 fhuC P ABC transporter
CLHAPNMH_00803 3.2e-128 znuB U ABC 3 transport family
CLHAPNMH_00804 7.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CLHAPNMH_00805 1.3e-204 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLHAPNMH_00806 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLHAPNMH_00807 4e-32
CLHAPNMH_00808 4.8e-143 yxeH S hydrolase
CLHAPNMH_00809 1.5e-266 ywfO S HD domain protein
CLHAPNMH_00810 3.2e-74 ywiB S Domain of unknown function (DUF1934)
CLHAPNMH_00811 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CLHAPNMH_00812 1.1e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CLHAPNMH_00813 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLHAPNMH_00814 6e-41 rpmE2 J Ribosomal protein L31
CLHAPNMH_00815 1.3e-49 mdtG EGP Major facilitator Superfamily
CLHAPNMH_00816 1.5e-55 mdtG EGP Major facilitator Superfamily
CLHAPNMH_00817 1.3e-137 IQ reductase
CLHAPNMH_00818 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
CLHAPNMH_00819 3.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CLHAPNMH_00820 3.1e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CLHAPNMH_00821 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CLHAPNMH_00822 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLHAPNMH_00823 3.3e-163 camS S sex pheromone
CLHAPNMH_00824 1.7e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLHAPNMH_00825 6.7e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CLHAPNMH_00826 1.5e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLHAPNMH_00827 1.9e-186 yegS 2.7.1.107 G Lipid kinase
CLHAPNMH_00828 6.6e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLHAPNMH_00829 9e-84 EGP Sugar (and other) transporter
CLHAPNMH_00830 5.1e-173 S Domain of unknown function (DUF389)
CLHAPNMH_00832 1.7e-293 L Recombinase
CLHAPNMH_00833 2.2e-288 L Recombinase zinc beta ribbon domain
CLHAPNMH_00834 5.4e-31
CLHAPNMH_00835 2e-134 M Glycosyl hydrolases family 25
CLHAPNMH_00836 1.7e-67 S Bacteriophage holin family
CLHAPNMH_00837 3.8e-66 S Phage head-tail joining protein
CLHAPNMH_00838 4.3e-43 S Phage gp6-like head-tail connector protein
CLHAPNMH_00839 2.5e-209 S Phage capsid family
CLHAPNMH_00840 2.6e-115 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
CLHAPNMH_00841 9.7e-244 S Phage portal protein
CLHAPNMH_00842 2.7e-304 S overlaps another CDS with the same product name
CLHAPNMH_00843 4.4e-29 S Domain of unknown function (DUF5049)
CLHAPNMH_00844 8.7e-113 S Psort location Cytoplasmic, score
CLHAPNMH_00845 2.9e-229 2.1.1.72 KL DNA methylase
CLHAPNMH_00846 3.1e-98
CLHAPNMH_00847 1.8e-67 V HNH nucleases
CLHAPNMH_00848 1.4e-75
CLHAPNMH_00849 5e-246 L SNF2 family N-terminal domain
CLHAPNMH_00850 8.1e-42 S VRR_NUC
CLHAPNMH_00851 0.0 S Phage plasmid primase, P4
CLHAPNMH_00852 1.9e-52 S Psort location Cytoplasmic, score
CLHAPNMH_00853 0.0 polA_2 2.7.7.7 L DNA polymerase
CLHAPNMH_00854 2.9e-99 S Protein of unknown function (DUF2815)
CLHAPNMH_00855 2.5e-206 L Protein of unknown function (DUF2800)
CLHAPNMH_00856 9.2e-42
CLHAPNMH_00857 7.5e-29
CLHAPNMH_00858 2.4e-66 K DNA-templated transcription, initiation
CLHAPNMH_00859 3.3e-57 T Nacht domain
CLHAPNMH_00860 5e-87
CLHAPNMH_00861 2.1e-182 S AAA domain
CLHAPNMH_00862 1.9e-248 EGP Major facilitator Superfamily
CLHAPNMH_00863 6e-185 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CLHAPNMH_00864 6.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLHAPNMH_00865 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLHAPNMH_00866 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLHAPNMH_00867 3.2e-50 ylxQ J ribosomal protein
CLHAPNMH_00868 1.4e-47 ylxR K Protein of unknown function (DUF448)
CLHAPNMH_00869 3.7e-224 nusA K Participates in both transcription termination and antitermination
CLHAPNMH_00870 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
CLHAPNMH_00871 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CLHAPNMH_00872 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CLHAPNMH_00873 1.1e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLHAPNMH_00874 1.2e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLHAPNMH_00875 2.7e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
CLHAPNMH_00876 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
CLHAPNMH_00877 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLHAPNMH_00878 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CLHAPNMH_00879 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CLHAPNMH_00880 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
CLHAPNMH_00881 1.3e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLHAPNMH_00882 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CLHAPNMH_00883 1.6e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CLHAPNMH_00884 5.5e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLHAPNMH_00885 1.1e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
CLHAPNMH_00886 8.7e-47 yazA L GIY-YIG catalytic domain protein
CLHAPNMH_00887 8e-137 yabB 2.1.1.223 L Methyltransferase small domain
CLHAPNMH_00888 3.3e-115 plsC 2.3.1.51 I Acyltransferase
CLHAPNMH_00889 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
CLHAPNMH_00890 9.2e-37 ynzC S UPF0291 protein
CLHAPNMH_00891 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLHAPNMH_00892 8.7e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
CLHAPNMH_00893 5.6e-122 lutA C Cysteine-rich domain
CLHAPNMH_00894 1.1e-244 lutB C 4Fe-4S dicluster domain
CLHAPNMH_00895 5.7e-87 yrjD S LUD domain
CLHAPNMH_00896 1.5e-36 UW LPXTG-motif cell wall anchor domain protein
CLHAPNMH_00898 3.4e-44 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CLHAPNMH_00899 2.7e-25 yitW S Iron-sulfur cluster assembly protein
CLHAPNMH_00900 7.1e-92 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CLHAPNMH_00901 4.8e-64 sdaAB 4.3.1.17 E Serine dehydratase beta chain
CLHAPNMH_00904 2.1e-06
CLHAPNMH_00905 4.4e-132 M lysozyme activity
CLHAPNMH_00906 1e-20 S Bacteriophage holin family
CLHAPNMH_00909 2.4e-197 S peptidoglycan catabolic process
CLHAPNMH_00910 4.2e-64 S Phage tail protein
CLHAPNMH_00911 8.7e-137 S peptidoglycan catabolic process
CLHAPNMH_00912 7.6e-39 S Pfam:Phage_TAC_12
CLHAPNMH_00913 4.7e-84 S Phage major tail protein 2
CLHAPNMH_00914 1.2e-43
CLHAPNMH_00915 1e-40 S exonuclease activity
CLHAPNMH_00916 6.4e-19
CLHAPNMH_00917 3.8e-42 S Phage gp6-like head-tail connector protein
CLHAPNMH_00918 8.7e-119
CLHAPNMH_00919 2.9e-65 S aminoacyl-tRNA ligase activity
CLHAPNMH_00921 7e-136 S Phage Mu protein F like protein
CLHAPNMH_00922 5e-209 S Phage portal protein, SPP1 Gp6-like
CLHAPNMH_00923 1.5e-164 S Phage terminase large subunit
CLHAPNMH_00924 1.4e-39 L Terminase small subunit
CLHAPNMH_00925 2.7e-23
CLHAPNMH_00926 1e-21
CLHAPNMH_00929 2.8e-34 S Protein of unknown function (DUF1064)
CLHAPNMH_00930 4.4e-10 K Cro/C1-type HTH DNA-binding domain
CLHAPNMH_00932 2.3e-41 dnaC 3.4.21.53 L IstB-like ATP binding protein
CLHAPNMH_00933 2.1e-86 S calcium ion binding
CLHAPNMH_00936 4.9e-63 S Single-strand binding protein family
CLHAPNMH_00937 1.9e-163 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
CLHAPNMH_00938 4.9e-150 recT L RecT family
CLHAPNMH_00941 7.7e-09 S Domain of unknown function (DUF771)
CLHAPNMH_00943 1.3e-13 K sequence-specific DNA binding
CLHAPNMH_00944 2.9e-22 K sequence-specific DNA binding
CLHAPNMH_00945 2.4e-31 xkdA E Zn peptidase
CLHAPNMH_00947 5.4e-22
CLHAPNMH_00948 2.7e-31
CLHAPNMH_00949 5.1e-124 L Belongs to the 'phage' integrase family
CLHAPNMH_00951 1.4e-89
CLHAPNMH_00952 1.3e-78 F Nucleoside 2-deoxyribosyltransferase
CLHAPNMH_00953 1.5e-183 scrR3 K Transcriptional regulator, LacI family
CLHAPNMH_00954 2.8e-12
CLHAPNMH_00955 1.5e-17 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
CLHAPNMH_00957 1.4e-12 S CHY zinc finger
CLHAPNMH_00960 0.0 asnB 6.3.5.4 E Aluminium induced protein
CLHAPNMH_00961 3.1e-63 acmD M repeat protein
CLHAPNMH_00962 4e-73 S enterobacterial common antigen metabolic process
CLHAPNMH_00963 1.2e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
CLHAPNMH_00964 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
CLHAPNMH_00965 4.5e-45 M biosynthesis protein
CLHAPNMH_00966 1.2e-94 cps3F
CLHAPNMH_00967 3.6e-145 cps1D M Domain of unknown function (DUF4422)
CLHAPNMH_00968 1.1e-118 rfbP M Bacterial sugar transferase
CLHAPNMH_00969 1.4e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
CLHAPNMH_00970 1.3e-07
CLHAPNMH_00971 3.8e-31 S Protein of unknown function (DUF2922)
CLHAPNMH_00972 2.7e-139 yihY S Belongs to the UPF0761 family
CLHAPNMH_00973 0.0 XK27_08315 M Sulfatase
CLHAPNMH_00974 8.5e-167 map 3.4.11.18 E Methionine Aminopeptidase
CLHAPNMH_00975 4.2e-77 fld C Flavodoxin
CLHAPNMH_00976 3e-75 gtcA S Teichoic acid glycosylation protein
CLHAPNMH_00979 8.9e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
CLHAPNMH_00980 4.9e-190 mocA S Oxidoreductase
CLHAPNMH_00981 4.9e-63 S Domain of unknown function (DUF4828)
CLHAPNMH_00982 6.8e-104 yvdD 3.2.2.10 S Belongs to the LOG family
CLHAPNMH_00983 1.9e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CLHAPNMH_00984 1.2e-288 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CLHAPNMH_00985 1.4e-139 S NADPH-dependent FMN reductase
CLHAPNMH_00986 2.3e-33 yneR S Belongs to the HesB IscA family
CLHAPNMH_00987 2.8e-304 ybiT S ABC transporter, ATP-binding protein
CLHAPNMH_00988 2e-85 dps P Belongs to the Dps family
CLHAPNMH_00989 1.6e-105
CLHAPNMH_00990 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CLHAPNMH_00991 4e-101 K helix_turn_helix multiple antibiotic resistance protein
CLHAPNMH_00992 3.4e-49 fsr EGP Major Facilitator Superfamily
CLHAPNMH_00993 5.1e-81 fsr EGP Major Facilitator Superfamily
CLHAPNMH_00994 2.7e-99 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLHAPNMH_00995 3.3e-101 S CAAX protease self-immunity
CLHAPNMH_00997 5.3e-119 Q Methyltransferase domain
CLHAPNMH_00998 9.6e-90 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
CLHAPNMH_00999 2.8e-51 K 2 iron, 2 sulfur cluster binding
CLHAPNMH_01000 0.0 mco Q Multicopper oxidase
CLHAPNMH_01001 1.4e-89 S Aminoacyl-tRNA editing domain
CLHAPNMH_01002 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
CLHAPNMH_01004 1.9e-192 nhaC C Na H antiporter NhaC
CLHAPNMH_01005 2.5e-186 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
CLHAPNMH_01007 2.9e-162 F DNA/RNA non-specific endonuclease
CLHAPNMH_01008 1.2e-69 L nuclease
CLHAPNMH_01009 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLHAPNMH_01010 6.4e-22
CLHAPNMH_01011 9.7e-278 mntH P H( )-stimulated, divalent metal cation uptake system
CLHAPNMH_01012 2.4e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
CLHAPNMH_01013 3.7e-108 ygfC K Bacterial regulatory proteins, tetR family
CLHAPNMH_01014 5e-158 hrtB V ABC transporter permease
CLHAPNMH_01015 6.1e-123 devA 3.6.3.25 V ABC transporter, ATP-binding protein
CLHAPNMH_01016 1.8e-75 argR K Regulates arginine biosynthesis genes
CLHAPNMH_01017 2.6e-46 czrA K Transcriptional regulator, ArsR family
CLHAPNMH_01018 1.3e-173 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CLHAPNMH_01019 2e-169 scrR K Transcriptional regulator, LacI family
CLHAPNMH_01020 9.5e-26
CLHAPNMH_01021 4.1e-102
CLHAPNMH_01022 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLHAPNMH_01023 8.5e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
CLHAPNMH_01024 5.6e-55
CLHAPNMH_01025 4.8e-125 yrkL S Flavodoxin-like fold
CLHAPNMH_01027 6.8e-65 yeaO S Protein of unknown function, DUF488
CLHAPNMH_01028 6.5e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CLHAPNMH_01029 5.5e-206 3.1.3.1 S associated with various cellular activities
CLHAPNMH_01030 9.3e-212 S Putative metallopeptidase domain
CLHAPNMH_01031 2.1e-45
CLHAPNMH_01032 2e-228 pbuG S permease
CLHAPNMH_01033 0.0 pepO 3.4.24.71 O Peptidase family M13
CLHAPNMH_01034 3.1e-92 ymdB S Macro domain protein
CLHAPNMH_01035 6.9e-147 pnuC H nicotinamide mononucleotide transporter
CLHAPNMH_01036 1.7e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CLHAPNMH_01037 3.1e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLHAPNMH_01038 2e-52
CLHAPNMH_01039 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CLHAPNMH_01040 5.3e-119 tcyB U Binding-protein-dependent transport system inner membrane component
CLHAPNMH_01041 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CLHAPNMH_01042 6.9e-36
CLHAPNMH_01043 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
CLHAPNMH_01044 4.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
CLHAPNMH_01045 1.2e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
CLHAPNMH_01046 2.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLHAPNMH_01047 4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CLHAPNMH_01048 2.3e-179 galR K Transcriptional regulator
CLHAPNMH_01049 0.0 rafA 3.2.1.22 G alpha-galactosidase
CLHAPNMH_01050 6.6e-276 lacS G Transporter
CLHAPNMH_01051 1e-243 fucP G Major Facilitator Superfamily
CLHAPNMH_01052 1.3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CLHAPNMH_01053 5e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLHAPNMH_01054 9.2e-170 deoR K sugar-binding domain protein
CLHAPNMH_01055 1.1e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLHAPNMH_01056 1.1e-200 S Domain of unknown function (DUF4432)
CLHAPNMH_01057 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLHAPNMH_01058 3.7e-260 G PTS system Galactitol-specific IIC component
CLHAPNMH_01059 6e-188 K helix_turn _helix lactose operon repressor
CLHAPNMH_01060 1.3e-282 yjeM E Amino Acid
CLHAPNMH_01062 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CLHAPNMH_01063 3.3e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
CLHAPNMH_01064 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
CLHAPNMH_01065 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLHAPNMH_01066 1.2e-129
CLHAPNMH_01067 2.8e-263 pipD E Dipeptidase
CLHAPNMH_01068 2.6e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
CLHAPNMH_01069 8.9e-87 M1-874 K Domain of unknown function (DUF1836)
CLHAPNMH_01070 2e-86 GM epimerase
CLHAPNMH_01071 1.4e-251 yhdP S Transporter associated domain
CLHAPNMH_01072 2.4e-83 nrdI F Belongs to the NrdI family
CLHAPNMH_01073 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
CLHAPNMH_01074 1.3e-205 yeaN P Transporter, major facilitator family protein
CLHAPNMH_01075 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLHAPNMH_01076 1.2e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CLHAPNMH_01077 2e-80 uspA T universal stress protein
CLHAPNMH_01078 8.7e-78 K AsnC family
CLHAPNMH_01079 1.9e-141 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLHAPNMH_01080 4.7e-177 K helix_turn _helix lactose operon repressor
CLHAPNMH_01081 0.0 pepF E oligoendopeptidase F
CLHAPNMH_01082 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CLHAPNMH_01083 3.1e-124 S Membrane
CLHAPNMH_01084 1.3e-28 L Transposase
CLHAPNMH_01085 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
CLHAPNMH_01086 2.6e-184 S interspecies interaction between organisms
CLHAPNMH_01087 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
CLHAPNMH_01088 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLHAPNMH_01089 6.3e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CLHAPNMH_01090 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLHAPNMH_01091 2e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLHAPNMH_01092 2e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLHAPNMH_01093 2.8e-61 rplQ J Ribosomal protein L17
CLHAPNMH_01094 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLHAPNMH_01095 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLHAPNMH_01096 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLHAPNMH_01097 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CLHAPNMH_01098 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLHAPNMH_01099 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CLHAPNMH_01100 2.6e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CLHAPNMH_01101 5.6e-66 rplO J Binds to the 23S rRNA
CLHAPNMH_01102 6.5e-24 rpmD J Ribosomal protein L30
CLHAPNMH_01103 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLHAPNMH_01104 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLHAPNMH_01105 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLHAPNMH_01106 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLHAPNMH_01107 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLHAPNMH_01108 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLHAPNMH_01109 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLHAPNMH_01110 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLHAPNMH_01111 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLHAPNMH_01112 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
CLHAPNMH_01113 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLHAPNMH_01114 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLHAPNMH_01115 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLHAPNMH_01116 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLHAPNMH_01117 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLHAPNMH_01118 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CLHAPNMH_01119 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
CLHAPNMH_01120 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLHAPNMH_01121 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CLHAPNMH_01122 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLHAPNMH_01123 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CLHAPNMH_01124 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLHAPNMH_01125 2.1e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
CLHAPNMH_01126 7.4e-214 ykiI
CLHAPNMH_01127 1.6e-134 puuD S peptidase C26
CLHAPNMH_01128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLHAPNMH_01129 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLHAPNMH_01130 5.8e-106 K Bacterial regulatory proteins, tetR family
CLHAPNMH_01131 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CLHAPNMH_01132 4.8e-79 ctsR K Belongs to the CtsR family
CLHAPNMH_01133 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
CLHAPNMH_01134 1.9e-132 XK27_07210 6.1.1.6 S B3 4 domain
CLHAPNMH_01135 2.7e-120 J 2'-5' RNA ligase superfamily
CLHAPNMH_01136 1.5e-38 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
CLHAPNMH_01138 1.9e-236 N Uncharacterized conserved protein (DUF2075)
CLHAPNMH_01139 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLHAPNMH_01141 1.5e-253 yifK E Amino acid permease
CLHAPNMH_01143 2.5e-269 pipD E Dipeptidase
CLHAPNMH_01144 1.2e-163 endA F DNA RNA non-specific endonuclease
CLHAPNMH_01145 2.2e-165 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
CLHAPNMH_01146 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLHAPNMH_01147 3.1e-153 S Alpha/beta hydrolase of unknown function (DUF915)
CLHAPNMH_01149 9.2e-228
CLHAPNMH_01150 3.4e-194 V Beta-lactamase
CLHAPNMH_01151 1.4e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
CLHAPNMH_01152 9.1e-125 S membrane transporter protein
CLHAPNMH_01153 2.5e-179 S AI-2E family transporter
CLHAPNMH_01154 8.8e-215 phbA 2.3.1.9 I Belongs to the thiolase family
CLHAPNMH_01155 4.5e-160 rssA S Phospholipase, patatin family
CLHAPNMH_01156 7.5e-169 K LysR substrate binding domain
CLHAPNMH_01157 0.0 1.3.5.4 C FAD binding domain
CLHAPNMH_01158 1.3e-73 S Domain of unknown function (DUF4352)
CLHAPNMH_01159 6.8e-114 yicL EG EamA-like transporter family
CLHAPNMH_01160 3.3e-64
CLHAPNMH_01162 6.3e-34
CLHAPNMH_01163 1.6e-67 S pyridoxamine 5-phosphate
CLHAPNMH_01164 2.8e-179 yobV1 K WYL domain
CLHAPNMH_01165 1.8e-243 XK27_08635 S UPF0210 protein
CLHAPNMH_01166 2.5e-40 gcvR T Belongs to the UPF0237 family
CLHAPNMH_01167 1.4e-167 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CLHAPNMH_01168 1.5e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CLHAPNMH_01169 3.3e-217 G Transporter, major facilitator family protein
CLHAPNMH_01170 3.1e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CLHAPNMH_01171 5.3e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLHAPNMH_01172 4.3e-62 ydiI Q Thioesterase superfamily
CLHAPNMH_01173 2.4e-36 citG 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CLHAPNMH_01174 2e-16 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CLHAPNMH_01175 9.7e-19 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CLHAPNMH_01176 1.5e-18 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CLHAPNMH_01177 1e-73 ydjP I Alpha/beta hydrolase family
CLHAPNMH_01178 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CLHAPNMH_01179 3e-257 nylA 3.5.1.4 J Belongs to the amidase family
CLHAPNMH_01180 1.5e-203 arcD S C4-dicarboxylate anaerobic carrier
CLHAPNMH_01181 3.1e-192 ytjP 3.5.1.18 E Dipeptidase
CLHAPNMH_01182 1.9e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CLHAPNMH_01183 8.9e-83 F Hydrolase, NUDIX family
CLHAPNMH_01184 1.2e-211 S Type IV secretion-system coupling protein DNA-binding domain
CLHAPNMH_01185 0.0 tetP J elongation factor G
CLHAPNMH_01186 2.6e-188 L Helix-turn-helix domain
CLHAPNMH_01187 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CLHAPNMH_01188 2.5e-109 ypsA S Belongs to the UPF0398 family
CLHAPNMH_01189 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CLHAPNMH_01190 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
CLHAPNMH_01191 3.7e-160 EG EamA-like transporter family
CLHAPNMH_01192 5.3e-192 C Aldo keto reductase family protein
CLHAPNMH_01193 1.3e-121 ypuA S Protein of unknown function (DUF1002)
CLHAPNMH_01194 4.7e-134 dnaD L DnaD domain protein
CLHAPNMH_01195 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
CLHAPNMH_01196 1.6e-88 ypmB S Protein conserved in bacteria
CLHAPNMH_01197 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CLHAPNMH_01198 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CLHAPNMH_01199 8.2e-182 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CLHAPNMH_01200 2.1e-210 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CLHAPNMH_01201 4.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CLHAPNMH_01202 1.6e-95 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CLHAPNMH_01203 1.3e-103 pstA P Phosphate transport system permease protein PstA
CLHAPNMH_01204 2.4e-98 pstC P probably responsible for the translocation of the substrate across the membrane
CLHAPNMH_01205 4.5e-91 pstS P Phosphate ABC transporter substrate-binding protein, PhoT family
CLHAPNMH_01206 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
CLHAPNMH_01207 4.2e-29 EGP Major facilitator Superfamily
CLHAPNMH_01208 0.0 copA 3.6.3.54 P P-type ATPase
CLHAPNMH_01209 1.2e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CLHAPNMH_01210 5.5e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CLHAPNMH_01211 1.1e-176
CLHAPNMH_01212 7.9e-224 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
CLHAPNMH_01213 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLHAPNMH_01214 1.7e-240 purD 6.3.4.13 F Belongs to the GARS family
CLHAPNMH_01215 1.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CLHAPNMH_01216 2.3e-107 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLHAPNMH_01217 7.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CLHAPNMH_01218 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLHAPNMH_01219 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLHAPNMH_01220 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLHAPNMH_01221 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLHAPNMH_01222 2.5e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CLHAPNMH_01223 5.3e-236 S response to antibiotic
CLHAPNMH_01224 2.7e-156 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
CLHAPNMH_01225 1.2e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLHAPNMH_01226 2.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLHAPNMH_01227 1.8e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLHAPNMH_01228 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CLHAPNMH_01229 4.7e-153 K AI-2E family transporter
CLHAPNMH_01230 2.1e-11 K transcriptional regulator
CLHAPNMH_01231 1.8e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CLHAPNMH_01232 5.1e-101 ydeN S Serine hydrolase
CLHAPNMH_01233 1.5e-133 L PFAM transposase, IS4 family protein
CLHAPNMH_01234 1.5e-64 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
CLHAPNMH_01235 5.3e-79 mleR K LysR family
CLHAPNMH_01236 1.2e-230 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
CLHAPNMH_01237 2.1e-183 XK27_09615 S reductase
CLHAPNMH_01238 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
CLHAPNMH_01239 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CLHAPNMH_01240 6.7e-214 frdC 1.3.5.4 C FAD binding domain
CLHAPNMH_01241 5.6e-224 yflS P Sodium:sulfate symporter transmembrane region
CLHAPNMH_01242 1.7e-162 mleR K LysR family transcriptional regulator
CLHAPNMH_01243 2.1e-252 yjjP S Putative threonine/serine exporter
CLHAPNMH_01244 7.2e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
CLHAPNMH_01245 2.4e-189 I Alpha beta
CLHAPNMH_01246 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
CLHAPNMH_01247 7.2e-236 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLHAPNMH_01248 4.9e-238 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLHAPNMH_01250 2e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CLHAPNMH_01251 4.2e-149 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
CLHAPNMH_01252 4.4e-113 S Domain of unknown function (DUF4811)
CLHAPNMH_01253 1.1e-267 lmrB EGP Major facilitator Superfamily
CLHAPNMH_01254 1.9e-74 merR K MerR HTH family regulatory protein
CLHAPNMH_01255 5.8e-58
CLHAPNMH_01256 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLHAPNMH_01257 8.2e-216 S CAAX protease self-immunity
CLHAPNMH_01258 8.1e-33 elaA S GNAT family
CLHAPNMH_01259 4.5e-85 usp1 T Belongs to the universal stress protein A family
CLHAPNMH_01260 1.5e-75 S VIT family
CLHAPNMH_01261 4e-127 narI 1.7.5.1 C Nitrate reductase
CLHAPNMH_01262 3.5e-101 narJ C Nitrate reductase delta subunit
CLHAPNMH_01263 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
CLHAPNMH_01264 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CLHAPNMH_01265 1.8e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
CLHAPNMH_01266 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
CLHAPNMH_01267 4.1e-231 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
CLHAPNMH_01268 7.2e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CLHAPNMH_01269 2.4e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CLHAPNMH_01270 4.2e-40
CLHAPNMH_01271 1.4e-77 nreA T GAF domain
CLHAPNMH_01272 1.6e-183 comP 2.7.13.3 F Sensor histidine kinase
CLHAPNMH_01273 3e-116 nreC K PFAM regulatory protein LuxR
CLHAPNMH_01274 1.2e-39
CLHAPNMH_01275 3e-184
CLHAPNMH_01276 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
CLHAPNMH_01278 4.6e-134 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CLHAPNMH_01279 4.5e-163 hipB K Helix-turn-helix
CLHAPNMH_01280 1.5e-58 yitW S Iron-sulfur cluster assembly protein
CLHAPNMH_01281 2.4e-215 narK P Major Facilitator Superfamily
CLHAPNMH_01282 7.8e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLHAPNMH_01283 1.1e-34 moaD 2.8.1.12 H ThiS family
CLHAPNMH_01284 2.2e-72 moaE 2.8.1.12 H MoaE protein
CLHAPNMH_01285 6e-55 S Flavodoxin
CLHAPNMH_01286 1.6e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLHAPNMH_01287 5e-142 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
CLHAPNMH_01288 1.5e-228 ndh 1.6.99.3 C NADH dehydrogenase
CLHAPNMH_01289 8e-54 yitW S Iron-sulfur cluster assembly protein
CLHAPNMH_01290 6.1e-19 M1-755 S Domain of unknown function (DUF1858)
CLHAPNMH_01291 1.6e-257 XK27_04775 S PAS domain
CLHAPNMH_01292 2.1e-141 EG EamA-like transporter family
CLHAPNMH_01293 0.0 yeeA V Type II restriction enzyme, methylase subunits
CLHAPNMH_01294 0.0 yeeB L DEAD-like helicases superfamily
CLHAPNMH_01295 6.1e-179 pstS P T5orf172
CLHAPNMH_01296 2.4e-30 L Transposase and inactivated derivatives IS30 family
CLHAPNMH_01297 3.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLHAPNMH_01298 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLHAPNMH_01299 4.9e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CLHAPNMH_01300 2.3e-104 wecD3 K Acetyltransferase (GNAT) family
CLHAPNMH_01301 0.0 ubiB S ABC1 family
CLHAPNMH_01302 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
CLHAPNMH_01303 2.3e-170 GK ROK family
CLHAPNMH_01304 1.5e-40
CLHAPNMH_01305 4.2e-80 copY K Copper transport repressor CopY TcrY
CLHAPNMH_01307 5e-73 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
CLHAPNMH_01308 4.3e-50 mutR K Transcriptional activator, Rgg GadR MutR family
CLHAPNMH_01309 9.1e-107 mutR K Transcriptional activator, Rgg GadR MutR family
CLHAPNMH_01310 3.5e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
CLHAPNMH_01311 2.7e-228 gntT EG Gluconate
CLHAPNMH_01312 2.2e-182 K Transcriptional regulator, LacI family
CLHAPNMH_01313 2.5e-61 yneR
CLHAPNMH_01314 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CLHAPNMH_01315 2.2e-96 V VanZ like family
CLHAPNMH_01316 3.1e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CLHAPNMH_01317 2.4e-49 ywnB S NAD(P)H-binding
CLHAPNMH_01318 3.5e-65 yjcE P Sodium proton antiporter
CLHAPNMH_01319 5.9e-76
CLHAPNMH_01320 1.9e-183
CLHAPNMH_01321 1.7e-215 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CLHAPNMH_01322 3.4e-180 S Protein of unknown function (DUF2785)
CLHAPNMH_01324 2.2e-221 rodA D Belongs to the SEDS family
CLHAPNMH_01325 7.9e-32 S Protein of unknown function (DUF2969)
CLHAPNMH_01326 2.6e-183 mbl D Cell shape determining protein MreB Mrl
CLHAPNMH_01327 5.5e-220 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
CLHAPNMH_01328 2.8e-29 S Protein of unknown function (DUF1146)
CLHAPNMH_01329 1.7e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CLHAPNMH_01330 1.3e-252 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLHAPNMH_01331 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLHAPNMH_01332 4.7e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLHAPNMH_01333 7.4e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLHAPNMH_01334 3.7e-53 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLHAPNMH_01335 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLHAPNMH_01336 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
CLHAPNMH_01337 5.4e-218 pyrP F Permease
CLHAPNMH_01338 3.3e-125 yibF S overlaps another CDS with the same product name
CLHAPNMH_01339 1.1e-185 yibE S overlaps another CDS with the same product name
CLHAPNMH_01340 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLHAPNMH_01341 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLHAPNMH_01342 2.8e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CLHAPNMH_01343 7.1e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CLHAPNMH_01344 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLHAPNMH_01345 1.6e-108 tdk 2.7.1.21 F thymidine kinase
CLHAPNMH_01346 7.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
CLHAPNMH_01347 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
CLHAPNMH_01348 2.8e-48
CLHAPNMH_01349 1.3e-226 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLHAPNMH_01350 9.4e-144 S Oxidoreductase family, NAD-binding Rossmann fold
CLHAPNMH_01352 4.5e-166 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CLHAPNMH_01353 9.7e-179 S Phosphotransferase system, EIIC
CLHAPNMH_01354 2.1e-23 D mRNA cleavage
CLHAPNMH_01355 7.2e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
CLHAPNMH_01356 1.2e-264 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CLHAPNMH_01357 1.2e-267 bglP 2.7.1.211 G phosphotransferase system
CLHAPNMH_01358 4.5e-112 licT K CAT RNA binding domain
CLHAPNMH_01359 2.7e-66 S Domain of unknown function (DUF3841)
CLHAPNMH_01360 1.3e-119 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLHAPNMH_01361 2.5e-15
CLHAPNMH_01362 1.1e-62 yjbR S YjbR
CLHAPNMH_01363 2.6e-115 S Sel1-like repeats.
CLHAPNMH_01364 6.2e-89 K Psort location CytoplasmicMembrane, score
CLHAPNMH_01365 7.1e-83 K Helix-turn-helix XRE-family like proteins
CLHAPNMH_01366 2.2e-50 K TRANSCRIPTIONal
CLHAPNMH_01367 1.8e-24
CLHAPNMH_01368 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
CLHAPNMH_01369 1.9e-114 3.1.21.3 V Type I restriction modification DNA specificity domain
CLHAPNMH_01370 0.0 2.1.1.72 V type I restriction-modification system
CLHAPNMH_01371 1.7e-86 S AAA domain
CLHAPNMH_01372 1.5e-138 L Transposase DDE domain group 1
CLHAPNMH_01373 1.1e-14 S peptidoglycan binding
CLHAPNMH_01374 1.2e-111 nss M transferase activity, transferring glycosyl groups
CLHAPNMH_01375 1.3e-88 secY2 U SecY translocase
CLHAPNMH_01376 1.4e-103 asp1 S Accessory Sec system protein Asp1
CLHAPNMH_01377 1.4e-130 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
CLHAPNMH_01378 1.9e-19 asp3 S Accessory Sec secretory system ASP3
CLHAPNMH_01379 6.4e-273 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CLHAPNMH_01381 4.3e-166 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CLHAPNMH_01382 4.4e-130 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CLHAPNMH_01383 4.6e-115 yecS E ABC transporter permease
CLHAPNMH_01384 1e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
CLHAPNMH_01385 6.5e-105 XK27_02070 S Nitroreductase family
CLHAPNMH_01386 1.5e-68 rnhA 3.1.26.4 L Ribonuclease HI
CLHAPNMH_01387 1.7e-70 esbA S Family of unknown function (DUF5322)
CLHAPNMH_01388 5.1e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLHAPNMH_01389 3.4e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CLHAPNMH_01390 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
CLHAPNMH_01391 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CLHAPNMH_01392 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
CLHAPNMH_01395 3.6e-29 S Domain of unknown function (DUF4767)
CLHAPNMH_01396 1e-42 S Tautomerase enzyme
CLHAPNMH_01397 8.2e-10 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
CLHAPNMH_01398 3e-13 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
CLHAPNMH_01399 2e-120 pnb C nitroreductase
CLHAPNMH_01400 1.3e-102 S Alpha/beta hydrolase family
CLHAPNMH_01402 1.6e-44 K Bacterial regulatory helix-turn-helix protein, lysR family
CLHAPNMH_01403 5.3e-15 K Bacterial regulatory helix-turn-helix protein, lysR family
CLHAPNMH_01404 6.3e-39 C Aldo keto reductase
CLHAPNMH_01407 1.7e-16 C Aldo/keto reductase family
CLHAPNMH_01408 3.1e-93 P Cadmium resistance transporter
CLHAPNMH_01409 6e-32 ydzE EG spore germination
CLHAPNMH_01410 1.5e-53 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLHAPNMH_01411 6.7e-41
CLHAPNMH_01412 3.2e-280 isdH M Iron Transport-associated domain
CLHAPNMH_01413 1.4e-94 M Iron Transport-associated domain
CLHAPNMH_01414 6.3e-149 isdE P Periplasmic binding protein
CLHAPNMH_01415 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLHAPNMH_01416 2.1e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
CLHAPNMH_01417 6.5e-235 kgtP EGP Sugar (and other) transporter
CLHAPNMH_01418 4.9e-07 S YSIRK type signal peptide
CLHAPNMH_01420 3.7e-29
CLHAPNMH_01421 1.9e-158 xth 3.1.11.2 L exodeoxyribonuclease III
CLHAPNMH_01422 4.7e-123 srtA 3.4.22.70 M sortase family
CLHAPNMH_01423 3.1e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLHAPNMH_01424 1.9e-87 lemA S LemA family
CLHAPNMH_01425 4.9e-157 htpX O Belongs to the peptidase M48B family
CLHAPNMH_01426 2.1e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CLHAPNMH_01427 6.6e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CLHAPNMH_01428 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CLHAPNMH_01429 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLHAPNMH_01430 5e-57 L Toxic component of a toxin-antitoxin (TA) module
CLHAPNMH_01431 8.1e-114 S (CBS) domain
CLHAPNMH_01432 8.2e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CLHAPNMH_01433 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLHAPNMH_01434 1.6e-39 yabO J S4 domain protein
CLHAPNMH_01435 1.5e-56 divIC D Septum formation initiator
CLHAPNMH_01436 3e-87 yabR J RNA binding
CLHAPNMH_01437 1.8e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CLHAPNMH_01438 9.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CLHAPNMH_01439 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLHAPNMH_01440 1.3e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLHAPNMH_01441 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLHAPNMH_01442 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CLHAPNMH_01444 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CLHAPNMH_01445 7.8e-114 2.7.6.5 T Region found in RelA / SpoT proteins
CLHAPNMH_01446 8e-80 K response regulator
CLHAPNMH_01447 2.9e-131 sptS 2.7.13.3 T Histidine kinase
CLHAPNMH_01448 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
CLHAPNMH_01449 2.3e-104 2.3.1.128 K acetyltransferase
CLHAPNMH_01450 3.4e-135 IQ Dehydrogenase reductase
CLHAPNMH_01451 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CLHAPNMH_01452 2.4e-159 EG EamA-like transporter family
CLHAPNMH_01453 0.0 helD 3.6.4.12 L DNA helicase
CLHAPNMH_01454 1.3e-114 dedA S SNARE associated Golgi protein
CLHAPNMH_01455 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
CLHAPNMH_01456 4e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLHAPNMH_01457 4e-209 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CLHAPNMH_01458 2.3e-133 pnuC H nicotinamide mononucleotide transporter
CLHAPNMH_01459 7.8e-299 ybeC E amino acid
CLHAPNMH_01460 2e-80 K FR47-like protein
CLHAPNMH_01461 0.0 yjcE P Sodium proton antiporter
CLHAPNMH_01462 1.2e-16 yvlA
CLHAPNMH_01463 2.2e-114 P Cobalt transport protein
CLHAPNMH_01464 1.2e-255 cbiO1 S ABC transporter, ATP-binding protein
CLHAPNMH_01465 1.6e-100 S ABC-type cobalt transport system, permease component
CLHAPNMH_01466 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
CLHAPNMH_01467 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
CLHAPNMH_01468 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
CLHAPNMH_01469 9.6e-33 copZ P Heavy-metal-associated domain
CLHAPNMH_01470 2e-100 dps P Belongs to the Dps family
CLHAPNMH_01471 7.4e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
CLHAPNMH_01472 2e-85
CLHAPNMH_01473 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CLHAPNMH_01474 2.1e-125 pgm3 G phosphoglycerate mutase family
CLHAPNMH_01475 7.2e-150 qorB 1.6.5.2 GM NmrA-like family
CLHAPNMH_01476 3.2e-229 pbuX F xanthine permease
CLHAPNMH_01477 2.6e-169 corA P CorA-like Mg2+ transporter protein
CLHAPNMH_01478 1.8e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CLHAPNMH_01479 7.5e-141 terC P membrane
CLHAPNMH_01480 1e-56 trxA1 O Belongs to the thioredoxin family
CLHAPNMH_01481 4.5e-177 3.4.11.5 E Releases the N-terminal proline from various substrates
CLHAPNMH_01482 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
CLHAPNMH_01483 3e-272 S Uncharacterized protein conserved in bacteria (DUF2325)
CLHAPNMH_01484 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
CLHAPNMH_01485 8.8e-170 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
CLHAPNMH_01486 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLHAPNMH_01487 3.1e-83 nrdI F NrdI Flavodoxin like
CLHAPNMH_01488 5.1e-110 M ErfK YbiS YcfS YnhG
CLHAPNMH_01490 9.8e-205 nrnB S DHHA1 domain
CLHAPNMH_01491 3.4e-291 S ABC transporter, ATP-binding protein
CLHAPNMH_01492 7e-181 ABC-SBP S ABC transporter
CLHAPNMH_01493 8.7e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
CLHAPNMH_01494 3.2e-133 XK27_08845 S ABC transporter, ATP-binding protein
CLHAPNMH_01496 1.6e-224 amtB P ammonium transporter
CLHAPNMH_01497 8.6e-235 mepA V MATE efflux family protein
CLHAPNMH_01498 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
CLHAPNMH_01499 2.3e-15 pgi 5.3.1.9 G Belongs to the GPI family
CLHAPNMH_01500 6.2e-131 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CLHAPNMH_01501 2.3e-43 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CLHAPNMH_01502 6.1e-40 ulaB 2.7.1.194 G Phosphotransferase system galactitol-specific IIB component
CLHAPNMH_01503 1.7e-193 ulaA 2.7.1.194 S PTS system sugar-specific permease component
CLHAPNMH_01504 7.5e-259 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLHAPNMH_01505 2e-123 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLHAPNMH_01506 4e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
CLHAPNMH_01507 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLHAPNMH_01508 5.5e-245 glpT G Major Facilitator Superfamily
CLHAPNMH_01509 1.6e-129 qmcA O prohibitin homologues
CLHAPNMH_01511 3.1e-75 uspA T universal stress protein
CLHAPNMH_01512 2.1e-59
CLHAPNMH_01513 6.6e-20
CLHAPNMH_01514 4.5e-160
CLHAPNMH_01515 8.4e-75 K Transcriptional regulator
CLHAPNMH_01516 4.1e-186 D Alpha beta
CLHAPNMH_01517 7.8e-73 O OsmC-like protein
CLHAPNMH_01518 1.8e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
CLHAPNMH_01519 7.5e-76 yphH S Cupin domain
CLHAPNMH_01520 1.3e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CLHAPNMH_01521 2.1e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CLHAPNMH_01522 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CLHAPNMH_01523 2.5e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CLHAPNMH_01524 1.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CLHAPNMH_01525 2.4e-136 cof S haloacid dehalogenase-like hydrolase
CLHAPNMH_01526 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CLHAPNMH_01527 6.8e-113 yfbR S HD containing hydrolase-like enzyme
CLHAPNMH_01529 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CLHAPNMH_01530 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CLHAPNMH_01531 7.6e-205
CLHAPNMH_01532 2.3e-159 rapZ S Displays ATPase and GTPase activities
CLHAPNMH_01533 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CLHAPNMH_01534 1.9e-167 whiA K May be required for sporulation
CLHAPNMH_01535 1.7e-119 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CLHAPNMH_01536 1.7e-36 K helix_turn_helix multiple antibiotic resistance protein
CLHAPNMH_01537 0.0 M domain protein
CLHAPNMH_01538 5.7e-19 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CLHAPNMH_01539 8.1e-111 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CLHAPNMH_01541 1.2e-93 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
CLHAPNMH_01542 4.7e-32 higA K Helix-turn-helix XRE-family like proteins
CLHAPNMH_01543 1.1e-30 S Sugar efflux transporter for intercellular exchange
CLHAPNMH_01544 1.4e-102 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
CLHAPNMH_01545 4.2e-37 tdh 1.1.1.14 C Zinc-binding dehydrogenase
CLHAPNMH_01546 3.5e-260 guaD 3.5.4.3 F Amidohydrolase family
CLHAPNMH_01547 6e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CLHAPNMH_01549 2.7e-57 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
CLHAPNMH_01550 3.3e-113 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CLHAPNMH_01551 1.8e-48 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
CLHAPNMH_01552 1.6e-88 rmeB K transcriptional regulator, MerR family
CLHAPNMH_01553 2.5e-133 ybbM S Uncharacterised protein family (UPF0014)
CLHAPNMH_01554 8.1e-114 ybbL S ABC transporter, ATP-binding protein
CLHAPNMH_01555 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CLHAPNMH_01556 1.3e-96 XK27_06785 V ABC transporter, ATP-binding protein
CLHAPNMH_01557 4.5e-232 XK27_06780 V ABC transporter permease
CLHAPNMH_01558 5.2e-90 E glutamate:sodium symporter activity
CLHAPNMH_01559 2.7e-75 3.4.17.11 E Peptidase dimerisation domain
CLHAPNMH_01560 6.8e-49 XK27_08850 S Aminoacyl-tRNA editing domain
CLHAPNMH_01561 6.3e-134 P nitric oxide dioxygenase activity
CLHAPNMH_01562 1.2e-66 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CLHAPNMH_01563 6.1e-50 S FMN_bind
CLHAPNMH_01564 0.0 yhcA V ABC transporter, ATP-binding protein
CLHAPNMH_01565 1.2e-123 bm3R1 K Bacterial regulatory proteins, tetR family
CLHAPNMH_01566 2.8e-33 rocF 3.5.3.1, 3.5.3.11 E Arginase family
CLHAPNMH_01568 2.1e-163 1.3.1.9 S Nitronate monooxygenase
CLHAPNMH_01569 4.7e-54 K Helix-turn-helix domain
CLHAPNMH_01570 1.8e-104 S Domain of unknown function (DUF4767)
CLHAPNMH_01572 1.2e-115
CLHAPNMH_01574 1.8e-279 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
CLHAPNMH_01575 1.6e-61
CLHAPNMH_01576 2.4e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CLHAPNMH_01577 6.9e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLHAPNMH_01578 0.0 dnaK O Heat shock 70 kDa protein
CLHAPNMH_01579 5.5e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CLHAPNMH_01580 1.6e-94 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLHAPNMH_01581 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CLHAPNMH_01582 1.9e-50 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CLHAPNMH_01583 8.9e-169 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
CLHAPNMH_01584 2.4e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CLHAPNMH_01585 5.8e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CLHAPNMH_01586 1.1e-229 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLHAPNMH_01587 3.8e-102 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CLHAPNMH_01588 6.1e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLHAPNMH_01589 5.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLHAPNMH_01590 2.1e-140 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CLHAPNMH_01591 2.9e-56 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLHAPNMH_01592 9.9e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
CLHAPNMH_01593 1.5e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLHAPNMH_01594 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CLHAPNMH_01595 1.4e-12 S Domain of unknown function (DUF4811)
CLHAPNMH_01598 3.5e-38 S Cytochrome B5
CLHAPNMH_01599 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CLHAPNMH_01600 4.9e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
CLHAPNMH_01601 1.1e-23 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
CLHAPNMH_01602 3.9e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
CLHAPNMH_01603 3.2e-104 3.2.1.17 NU mannosyl-glycoprotein
CLHAPNMH_01604 1.1e-95 wecD K Acetyltransferase (GNAT) family
CLHAPNMH_01605 5e-287 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
CLHAPNMH_01606 1.7e-81 S Psort location Cytoplasmic, score
CLHAPNMH_01607 2.3e-72 K helix_turn_helix, mercury resistance
CLHAPNMH_01608 4.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
CLHAPNMH_01609 1.7e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
CLHAPNMH_01610 2.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CLHAPNMH_01611 7.6e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
CLHAPNMH_01612 3.2e-125 ycsF S LamB/YcsF family
CLHAPNMH_01613 2.7e-211 ycsG P Natural resistance-associated macrophage protein
CLHAPNMH_01614 1.6e-208 EGP Major facilitator Superfamily
CLHAPNMH_01615 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
CLHAPNMH_01616 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLHAPNMH_01617 1.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
CLHAPNMH_01618 1.4e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CLHAPNMH_01619 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLHAPNMH_01620 4.7e-39 ptsH G phosphocarrier protein HPR
CLHAPNMH_01622 0.0 clpE O Belongs to the ClpA ClpB family
CLHAPNMH_01623 9.2e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
CLHAPNMH_01624 3.2e-109 pncA Q Isochorismatase family
CLHAPNMH_01625 1.7e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLHAPNMH_01626 1.7e-97 S Pfam:DUF3816
CLHAPNMH_01627 2.3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
CLHAPNMH_01628 1.3e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLHAPNMH_01629 6.5e-162 EG EamA-like transporter family
CLHAPNMH_01630 3.5e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
CLHAPNMH_01632 8.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLHAPNMH_01633 1.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
CLHAPNMH_01634 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLHAPNMH_01635 1.9e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CLHAPNMH_01636 2.6e-83 iolS C Aldo keto reductase
CLHAPNMH_01637 1.4e-243 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLHAPNMH_01638 5.2e-220 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CLHAPNMH_01639 5.8e-97 metI P ABC transporter permease
CLHAPNMH_01640 2.8e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLHAPNMH_01641 1e-148 metQ1 P Belongs to the nlpA lipoprotein family
CLHAPNMH_01642 1.3e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
CLHAPNMH_01643 9.2e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
CLHAPNMH_01644 6.9e-47
CLHAPNMH_01645 7.6e-21 gntT EG gluconate transmembrane transporter activity
CLHAPNMH_01646 3.3e-09
CLHAPNMH_01647 2.5e-112 3.1.3.73 G phosphoglycerate mutase
CLHAPNMH_01648 7.5e-18 C aldo keto reductase
CLHAPNMH_01649 1.2e-80 C aldo keto reductase
CLHAPNMH_01650 1.3e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLHAPNMH_01651 4.8e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLHAPNMH_01652 5.1e-267 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
CLHAPNMH_01653 2.1e-79 K 2 iron, 2 sulfur cluster binding
CLHAPNMH_01654 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CLHAPNMH_01655 1.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CLHAPNMH_01656 1.2e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
CLHAPNMH_01657 1e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLHAPNMH_01658 2.5e-54 C FMN binding
CLHAPNMH_01659 2.8e-63 T His Kinase A (phosphoacceptor) domain
CLHAPNMH_01660 2e-52 T Transcriptional regulatory protein, C terminal
CLHAPNMH_01661 2.3e-16 S ABC-type transport system involved in multi-copper enzyme maturation permease component
CLHAPNMH_01662 4.1e-220 iscS 2.8.1.7 E Aminotransferase class V
CLHAPNMH_01664 6.8e-11 L hmm pf00665
CLHAPNMH_01665 1.4e-107 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLHAPNMH_01666 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
CLHAPNMH_01667 2.5e-197 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
CLHAPNMH_01668 7.7e-301 scrB 3.2.1.26 GH32 G invertase
CLHAPNMH_01669 1.2e-260 S Uncharacterized protein conserved in bacteria (DUF2252)
CLHAPNMH_01670 5.9e-26 K Transcriptional
CLHAPNMH_01671 1.2e-68
CLHAPNMH_01672 1.9e-113 tnp L DDE domain
CLHAPNMH_01673 3.2e-164 K LysR substrate binding domain
CLHAPNMH_01674 1.5e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
CLHAPNMH_01675 1.1e-109
CLHAPNMH_01676 6.2e-266 yjeM E Amino Acid
CLHAPNMH_01677 3.7e-168 ponA V Beta-lactamase enzyme family
CLHAPNMH_01678 7.1e-212 nupG F Nucleoside transporter
CLHAPNMH_01679 7e-248 cycA E Amino acid permease
CLHAPNMH_01680 1e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CLHAPNMH_01681 1.7e-223 glnP P ABC transporter
CLHAPNMH_01683 1.4e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
CLHAPNMH_01685 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLHAPNMH_01686 0.0 sbcC L Putative exonuclease SbcCD, C subunit
CLHAPNMH_01687 1.4e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CLHAPNMH_01688 2.2e-144 rihC 3.2.2.1 F Nucleoside
CLHAPNMH_01689 3.1e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
CLHAPNMH_01690 9e-154 noc K Belongs to the ParB family
CLHAPNMH_01691 1e-145 spo0J K Belongs to the ParB family
CLHAPNMH_01692 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
CLHAPNMH_01693 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CLHAPNMH_01694 3.8e-134 XK27_01040 S Protein of unknown function (DUF1129)
CLHAPNMH_01695 7.7e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CLHAPNMH_01696 4.7e-169 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CLHAPNMH_01697 4.1e-128 epsB M biosynthesis protein
CLHAPNMH_01698 1.1e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
CLHAPNMH_01699 7.9e-140 ywqE 3.1.3.48 GM PHP domain protein
CLHAPNMH_01700 1.5e-132 cps2D 5.1.3.2 M RmlD substrate binding domain
CLHAPNMH_01701 7.7e-94 tuaA M Bacterial sugar transferase
CLHAPNMH_01702 1.3e-74 lsgF M Glycosyl transferase family 2
CLHAPNMH_01703 7.7e-41 M Pfam:DUF1792
CLHAPNMH_01704 1.2e-79 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
CLHAPNMH_01705 5.5e-15
CLHAPNMH_01706 4.7e-157 V ABC transporter, ATP-binding protein
CLHAPNMH_01707 5e-63 gntR1 K Transcriptional regulator, GntR family
CLHAPNMH_01708 4.7e-171 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CLHAPNMH_01709 2.5e-88 S Bacterial membrane protein, YfhO
CLHAPNMH_01710 4.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
CLHAPNMH_01711 1.3e-95 M transferase activity, transferring glycosyl groups
CLHAPNMH_01712 1.1e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLHAPNMH_01713 2.6e-164 ykoT GT2 M Glycosyl transferase family 2
CLHAPNMH_01714 1.2e-141 yueF S AI-2E family transporter
CLHAPNMH_01715 8.4e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
CLHAPNMH_01716 8.1e-09
CLHAPNMH_01717 6e-65 M repeat protein
CLHAPNMH_01718 5.9e-61 3.2.1.96, 3.5.1.28 GH73 M repeat protein
CLHAPNMH_01719 5e-23 mleP3 S Membrane transport protein
CLHAPNMH_01721 6.9e-240 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLHAPNMH_01722 2e-240 yfnA E amino acid
CLHAPNMH_01723 7.2e-83 S NADPH-dependent FMN reductase
CLHAPNMH_01725 5.9e-157 L Thioesterase-like superfamily
CLHAPNMH_01726 2.1e-260 argH 4.3.2.1 E argininosuccinate lyase
CLHAPNMH_01727 6e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CLHAPNMH_01728 5.4e-242 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLHAPNMH_01729 2.7e-64 L Transposase IS200 like
CLHAPNMH_01730 1.7e-173 L transposase, IS605 OrfB family
CLHAPNMH_01731 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLHAPNMH_01732 1.9e-93 K Transcriptional regulator
CLHAPNMH_01733 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CLHAPNMH_01734 4.6e-71 yqeY S YqeY-like protein
CLHAPNMH_01735 2.9e-179 phoH T phosphate starvation-inducible protein PhoH
CLHAPNMH_01736 1.1e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLHAPNMH_01737 1e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CLHAPNMH_01738 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLHAPNMH_01739 2.9e-156 recO L Involved in DNA repair and RecF pathway recombination
CLHAPNMH_01740 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CLHAPNMH_01741 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CLHAPNMH_01742 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CLHAPNMH_01743 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CLHAPNMH_01744 1.1e-153 L COG2801 Transposase and inactivated derivatives
CLHAPNMH_01745 1.3e-38 L Transposase and inactivated derivatives
CLHAPNMH_01746 2.5e-87
CLHAPNMH_01747 1.4e-22 rmeB K transcriptional regulator, MerR family
CLHAPNMH_01748 3e-71 thiW S Thiamine-precursor transporter protein (ThiW)
CLHAPNMH_01749 3e-53 S ABC-type cobalt transport system, permease component
CLHAPNMH_01750 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CLHAPNMH_01751 1.3e-45 IQ reductase
CLHAPNMH_01752 2e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLHAPNMH_01758 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CLHAPNMH_01759 3.9e-268 lysP E amino acid
CLHAPNMH_01761 8.3e-156 I alpha/beta hydrolase fold
CLHAPNMH_01762 1.2e-115 lssY 3.6.1.27 I phosphatase
CLHAPNMH_01763 2.8e-82 S Threonine/Serine exporter, ThrE
CLHAPNMH_01764 9.8e-127 thrE S Putative threonine/serine exporter
CLHAPNMH_01765 2.8e-28 cspA K Cold shock protein
CLHAPNMH_01766 4.5e-123 sirR K iron dependent repressor
CLHAPNMH_01767 1.7e-162 czcD P cation diffusion facilitator family transporter
CLHAPNMH_01768 2.5e-116 S membrane
CLHAPNMH_01769 2.5e-23 S VIT family
CLHAPNMH_01780 6.9e-142 ET Bacterial periplasmic substrate-binding proteins
CLHAPNMH_01781 2e-110 XK27_05795 P ABC transporter permease
CLHAPNMH_01782 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CLHAPNMH_01783 1.1e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLHAPNMH_01784 2.3e-159 sufD O Uncharacterized protein family (UPF0051)
CLHAPNMH_01785 4.6e-236 F Permease
CLHAPNMH_01786 4.6e-199 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
CLHAPNMH_01787 9.6e-62 lytE M LysM domain protein
CLHAPNMH_01788 1.6e-85 ykhA 3.1.2.20 I Thioesterase superfamily
CLHAPNMH_01789 1.1e-77 hsp O Belongs to the small heat shock protein (HSP20) family
CLHAPNMH_01790 5.4e-92 K Transcriptional regulator, TetR family
CLHAPNMH_01791 7.7e-206 V domain protein
CLHAPNMH_01792 2.5e-92 K Transcriptional regulator (TetR family)
CLHAPNMH_01793 3.6e-188 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CLHAPNMH_01794 1.3e-168
CLHAPNMH_01796 4e-83 zur P Belongs to the Fur family
CLHAPNMH_01797 1.3e-105 gmk2 2.7.4.8 F Guanylate kinase
CLHAPNMH_01798 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
CLHAPNMH_01799 1.1e-205 yfnA E Amino Acid
CLHAPNMH_01800 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CLHAPNMH_01801 3.9e-44 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLHAPNMH_01802 9.7e-194 ampC V Beta-lactamase
CLHAPNMH_01803 0.0 yfiC V ABC transporter
CLHAPNMH_01804 0.0 lmrA V ABC transporter, ATP-binding protein
CLHAPNMH_01805 4e-78 K Winged helix DNA-binding domain
CLHAPNMH_01806 1.6e-13
CLHAPNMH_01808 1e-56
CLHAPNMH_01810 9.5e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
CLHAPNMH_01811 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CLHAPNMH_01812 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
CLHAPNMH_01813 3.6e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
CLHAPNMH_01814 1.6e-85 K GNAT family
CLHAPNMH_01818 4e-22
CLHAPNMH_01819 2.7e-247 cycA E Amino acid permease
CLHAPNMH_01820 2.8e-84 perR P Belongs to the Fur family
CLHAPNMH_01821 1.8e-246 EGP Major facilitator Superfamily
CLHAPNMH_01822 1.3e-96 tag 3.2.2.20 L glycosylase
CLHAPNMH_01823 4.5e-52
CLHAPNMH_01824 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLHAPNMH_01825 3.7e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLHAPNMH_01826 3.4e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLHAPNMH_01827 7.1e-130 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
CLHAPNMH_01828 4.6e-57 ycsI S Protein of unknown function (DUF1445)
CLHAPNMH_01829 8.9e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CLHAPNMH_01830 2.8e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CLHAPNMH_01831 2.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CLHAPNMH_01832 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CLHAPNMH_01833 1.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CLHAPNMH_01834 7.7e-154 yitU 3.1.3.104 S hydrolase
CLHAPNMH_01835 4.1e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CLHAPNMH_01836 1.3e-48 L Initiator Replication protein
CLHAPNMH_01837 5.7e-65
CLHAPNMH_01838 2.1e-154 I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CLHAPNMH_01839 4.5e-183 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CLHAPNMH_01840 6.9e-42 K 2 iron, 2 sulfur cluster binding
CLHAPNMH_01841 1.5e-106 L Phage integrase family
CLHAPNMH_01842 2.1e-311 mco Q Multicopper oxidase
CLHAPNMH_01843 1.2e-177 D nuclear chromosome segregation
CLHAPNMH_01844 6e-128 L Initiator Replication protein
CLHAPNMH_01845 3.2e-223 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CLHAPNMH_01846 1.3e-96
CLHAPNMH_01847 1.9e-197 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CLHAPNMH_01848 4.7e-108 lssY 3.6.1.27 I Acid phosphatase homologues
CLHAPNMH_01849 6e-54 S MazG-like family
CLHAPNMH_01850 0.0 L Helicase C-terminal domain protein
CLHAPNMH_01851 3.2e-71 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
CLHAPNMH_01852 2.2e-96 K transcriptional regulator
CLHAPNMH_01853 8.6e-137 lmrB EGP Major facilitator Superfamily
CLHAPNMH_01854 2e-133 L PFAM transposase, IS4 family protein
CLHAPNMH_01855 1.5e-108 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
CLHAPNMH_01856 1.3e-127 G Phosphotransferase System
CLHAPNMH_01857 3.8e-40 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
CLHAPNMH_01858 2.2e-52 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CLHAPNMH_01859 1.9e-18 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CLHAPNMH_01860 4.8e-133 manR K PRD domain
CLHAPNMH_01861 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLHAPNMH_01862 1.7e-226 aadAT EK Aminotransferase, class I
CLHAPNMH_01863 1.5e-157 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CLHAPNMH_01864 7.5e-144 ET Bacterial periplasmic substrate-binding proteins
CLHAPNMH_01866 7.8e-221 I transferase activity, transferring acyl groups other than amino-acyl groups
CLHAPNMH_01868 8e-94 padC Q Phenolic acid decarboxylase
CLHAPNMH_01869 8.3e-99 padR K Virulence activator alpha C-term
CLHAPNMH_01870 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
CLHAPNMH_01871 1.1e-253 G Major Facilitator
CLHAPNMH_01872 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
CLHAPNMH_01873 9.4e-178 K Transcriptional regulator, LacI family
CLHAPNMH_01874 4.1e-157 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
CLHAPNMH_01875 4.6e-09
CLHAPNMH_01876 2.7e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
CLHAPNMH_01877 8.8e-66 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CLHAPNMH_01878 6.9e-101 K DNA-templated transcription, initiation
CLHAPNMH_01880 0.0 L Type III restriction enzyme, res subunit
CLHAPNMH_01881 2.8e-59 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
CLHAPNMH_01884 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CLHAPNMH_01885 4e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLHAPNMH_01886 1.5e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLHAPNMH_01887 0.0 asnB 6.3.5.4 E Asparagine synthase
CLHAPNMH_01888 3.3e-219 lysP E amino acid
CLHAPNMH_01889 7e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CLHAPNMH_01890 7.6e-97 ywrO S Flavodoxin-like fold
CLHAPNMH_01891 4.6e-45 S Protein conserved in bacteria
CLHAPNMH_01892 3e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
CLHAPNMH_01893 2.1e-51 S Sugar efflux transporter for intercellular exchange
CLHAPNMH_01894 1.7e-16 xre K Helix-turn-helix domain
CLHAPNMH_01895 6.3e-199 gldA 1.1.1.6 C dehydrogenase
CLHAPNMH_01896 5.1e-119 IQ Enoyl-(Acyl carrier protein) reductase
CLHAPNMH_01897 9.9e-08 S Bacterial transferase hexapeptide (six repeats)
CLHAPNMH_01899 2.6e-242 cycA E Amino acid permease
CLHAPNMH_01900 4.1e-253 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
CLHAPNMH_01901 1.5e-96 D Alpha beta
CLHAPNMH_01902 4.9e-52 ypaA S Protein of unknown function (DUF1304)
CLHAPNMH_01903 3e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLHAPNMH_01904 6.5e-75 K Copper transport repressor CopY TcrY
CLHAPNMH_01905 0.0 copB 3.6.3.4 P P-type ATPase
CLHAPNMH_01907 2.6e-51 L Resolvase, N terminal domain
CLHAPNMH_01908 3.5e-85 2.5.1.105 P Cation efflux family
CLHAPNMH_01909 7.6e-60 azlD S branched-chain amino acid
CLHAPNMH_01910 2.6e-139 azlC E AzlC protein
CLHAPNMH_01911 1.5e-204 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CLHAPNMH_01912 2e-208 hpk31 2.7.13.3 T Histidine kinase
CLHAPNMH_01913 1.8e-122 K response regulator
CLHAPNMH_01914 3.2e-80 S Cupin superfamily (DUF985)
CLHAPNMH_01915 2.3e-66 cps2I S Psort location CytoplasmicMembrane, score
CLHAPNMH_01916 1.7e-58 S Glycosyltransferase, group 2 family protein
CLHAPNMH_01917 7e-45 M Glycosyltransferase sugar-binding region containing DXD motif
CLHAPNMH_01918 1.5e-22 2.7.8.12 M Glycosyltransferase group 2 family protein
CLHAPNMH_01919 5.7e-124 S EcsC protein family
CLHAPNMH_01920 1.9e-26 tnp L DDE domain
CLHAPNMH_01921 2.2e-49 yqeB S Pyrimidine dimer DNA glycosylase
CLHAPNMH_01922 5.7e-177 L Transposase and inactivated derivatives, IS30 family
CLHAPNMH_01923 3.3e-43 L Transposase
CLHAPNMH_01924 6e-138 L COG2801 Transposase and inactivated derivatives
CLHAPNMH_01925 0.0 cadA P P-type ATPase
CLHAPNMH_01926 3.1e-11 pgi 5.3.1.9 G Belongs to the GPI family
CLHAPNMH_01927 5.1e-184 fruR3 K Transcriptional regulator, LacI family
CLHAPNMH_01928 9.4e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
CLHAPNMH_01929 7.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLHAPNMH_01930 7.1e-17 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CLHAPNMH_01931 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CLHAPNMH_01932 5.3e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CLHAPNMH_01933 6.1e-204 coiA 3.6.4.12 S Competence protein
CLHAPNMH_01934 9.5e-105 S T5orf172
CLHAPNMH_01936 4.8e-17 S zinc-ribbon domain
CLHAPNMH_01937 5e-120 mleP3 S Membrane transport protein
CLHAPNMH_01938 1.1e-52 trxA O Belongs to the thioredoxin family
CLHAPNMH_01939 2.9e-254 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
CLHAPNMH_01940 9.8e-77
CLHAPNMH_01941 3.1e-12 pgi 5.3.1.9 G Belongs to the GPI family
CLHAPNMH_01942 0.0 trxB2 1.8.1.9 C Thioredoxin domain
CLHAPNMH_01943 1.8e-104 ahpC 1.11.1.15 O Peroxiredoxin
CLHAPNMH_01944 9.3e-58 ysdA CP transmembrane transport
CLHAPNMH_01945 1.2e-78 natA S Domain of unknown function (DUF4162)
CLHAPNMH_01946 1.1e-289 L Transposase IS66 family
CLHAPNMH_01947 1.7e-22 XK27_01125 L PFAM IS66 Orf2 family protein
CLHAPNMH_01948 1.6e-122 3.6.1.3 S AAA domain
CLHAPNMH_01949 3e-163 L Mu transposase, C-terminal
CLHAPNMH_01951 2.6e-72 S Protease prsW family
CLHAPNMH_01952 5.6e-08 GT2,GT4 M transferase activity, transferring glycosyl groups
CLHAPNMH_01954 7.6e-145 L Transposase and inactivated derivatives
CLHAPNMH_01955 1.5e-24 L Helix-turn-helix domain
CLHAPNMH_01956 3.6e-85 L hmm pf00665
CLHAPNMH_01957 1.2e-126 L Helix-turn-helix domain
CLHAPNMH_01958 5.4e-133 L hmm pf00665
CLHAPNMH_01959 5.5e-128 L PFAM transposase, IS4 family protein
CLHAPNMH_01962 1e-69 S Asp23 family, cell envelope-related function
CLHAPNMH_01963 6e-12 S Transglycosylase associated protein
CLHAPNMH_01964 3.8e-16
CLHAPNMH_01965 1.2e-177 L transposase, IS605 OrfB family
CLHAPNMH_01966 1.5e-147 L transposase, IS605 OrfB family
CLHAPNMH_01967 6.4e-137 L Transposase and inactivated derivatives, IS30 family
CLHAPNMH_01978 5.5e-56 L Helix-turn-helix domain
CLHAPNMH_01979 5.8e-42 L Transposase DDE domain
CLHAPNMH_01980 3.4e-40 L Putative transposase of IS4/5 family (DUF4096)
CLHAPNMH_01981 4e-144 L PFAM Integrase catalytic region
CLHAPNMH_01982 1.4e-30 L Transposase
CLHAPNMH_01983 6e-103 L Integrase core domain
CLHAPNMH_01984 6.7e-10 S Membrane
CLHAPNMH_01985 2.4e-121 L transposase, IS605 OrfB family
CLHAPNMH_01986 2.8e-131 tra L Transposase and inactivated derivatives, IS30 family
CLHAPNMH_01987 5.7e-08 L Transposase
CLHAPNMH_01989 7e-43 L Helix-turn-helix domain
CLHAPNMH_01995 4.7e-85 L transposase, IS605 OrfB family
CLHAPNMH_01996 8.4e-25 sthIM 2.1.1.72 L DNA methylase
CLHAPNMH_01997 4e-15 tlpA2 L Transposase IS200 like
CLHAPNMH_01998 2e-34 L transposase, IS605 OrfB family
CLHAPNMH_01999 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
CLHAPNMH_02000 1.2e-48 tlpA2 L Transposase IS200 like
CLHAPNMH_02001 8.5e-54 pgi 5.3.1.9 G Belongs to the GPI family
CLHAPNMH_02002 3.1e-62 pgi 5.3.1.9 G Belongs to the GPI family
CLHAPNMH_02004 7.7e-52 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CLHAPNMH_02005 4.8e-27 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)