ORF_ID e_value Gene_name EC_number CAZy COGs Description
EIPGFFGA_00001 2.5e-21 fnt P Formate nitrite transporter
EIPGFFGA_00002 9.3e-231 XK27_09615 C reductase
EIPGFFGA_00003 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
EIPGFFGA_00004 1.4e-62 clpE O Belongs to the ClpA ClpB family
EIPGFFGA_00005 1.7e-287 clpE O Belongs to the ClpA ClpB family
EIPGFFGA_00006 4.3e-177 yubA S permease
EIPGFFGA_00007 9.3e-73 Q the current gene model (or a revised gene model) may contain a frame shift
EIPGFFGA_00008 5.6e-92 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EIPGFFGA_00009 5.3e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
EIPGFFGA_00010 1.7e-114 yxeN P ABC transporter (Permease
EIPGFFGA_00011 1.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
EIPGFFGA_00012 5e-10 S Protein of unknown function (DUF4059)
EIPGFFGA_00013 1.8e-245 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EIPGFFGA_00014 8.9e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EIPGFFGA_00015 3.8e-78 asp3 S Accessory Sec system protein Asp3
EIPGFFGA_00016 6.3e-90 asp2 3.4.11.5 S Accessory Sec system protein Asp2
EIPGFFGA_00017 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
EIPGFFGA_00018 8.2e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EIPGFFGA_00019 2.3e-87 ytsP 1.8.4.14 T GAF domain-containing protein
EIPGFFGA_00020 8.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EIPGFFGA_00021 8.6e-145 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EIPGFFGA_00022 1.8e-113 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EIPGFFGA_00023 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EIPGFFGA_00024 2.1e-227 noxE P NADH oxidase
EIPGFFGA_00025 9.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EIPGFFGA_00026 5.7e-10 O ADP-ribosylglycohydrolase
EIPGFFGA_00027 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
EIPGFFGA_00028 3e-60 ycaO O OsmC-like protein
EIPGFFGA_00029 2e-155 pstA P phosphate transport system permease
EIPGFFGA_00030 8e-112 pstC P probably responsible for the translocation of the substrate across the membrane
EIPGFFGA_00031 7.9e-88 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EIPGFFGA_00032 6.9e-33 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EIPGFFGA_00033 3e-104 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EIPGFFGA_00034 9.4e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EIPGFFGA_00035 7e-72 argR K Regulates arginine biosynthesis genes
EIPGFFGA_00036 5e-121 M domain protein
EIPGFFGA_00037 0.0 mdlB V abc transporter atp-binding protein
EIPGFFGA_00038 3.9e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EIPGFFGA_00039 2.1e-146 XK27_08360 S EDD domain protein, DegV family
EIPGFFGA_00040 5e-63 WQ51_03320 S cog cog4835
EIPGFFGA_00041 8e-99 metI P ABC transporter (Permease
EIPGFFGA_00042 3.9e-148 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EIPGFFGA_00043 3.3e-256 glnP P ABC transporter
EIPGFFGA_00044 2.2e-123 glnQ E abc transporter atp-binding protein
EIPGFFGA_00045 1.7e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EIPGFFGA_00046 6.1e-106 pbp2b 3.4.16.4 M penicillin-binding protein
EIPGFFGA_00047 2.3e-286 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
EIPGFFGA_00048 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EIPGFFGA_00049 2.3e-111 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EIPGFFGA_00050 3e-106 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
EIPGFFGA_00051 3.8e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
EIPGFFGA_00053 3e-60 divIC D Septum formation initiator
EIPGFFGA_00054 9.2e-15 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EIPGFFGA_00055 2.4e-276 nptA P COG1283 Na phosphate symporter
EIPGFFGA_00056 4.2e-308 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EIPGFFGA_00057 1.5e-81 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EIPGFFGA_00058 2.4e-121 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EIPGFFGA_00059 1.8e-223 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EIPGFFGA_00060 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EIPGFFGA_00061 1.6e-102 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EIPGFFGA_00062 6.6e-114 papP P ABC transporter (Permease
EIPGFFGA_00063 4.6e-107 P ABC transporter (Permease
EIPGFFGA_00064 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EIPGFFGA_00065 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EIPGFFGA_00066 6.1e-123 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EIPGFFGA_00067 3.9e-99 thiT S Thiamine transporter
EIPGFFGA_00068 3.3e-62 yjqA S Bacterial PH domain
EIPGFFGA_00069 1.3e-152 corA P CorA-like protein
EIPGFFGA_00070 1.3e-79 hmpT S cog cog4720
EIPGFFGA_00071 1.5e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
EIPGFFGA_00072 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EIPGFFGA_00073 3.7e-48 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EIPGFFGA_00074 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EIPGFFGA_00075 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EIPGFFGA_00076 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EIPGFFGA_00077 9.3e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
EIPGFFGA_00078 2.7e-153 XK27_05675 S Esterase
EIPGFFGA_00079 3.1e-29 XK27_05670 S Putative esterase
EIPGFFGA_00080 3.4e-149 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EIPGFFGA_00082 1.4e-212 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EIPGFFGA_00083 9.5e-29 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
EIPGFFGA_00084 4.3e-31 S Beta-lactamase superfamily domain
EIPGFFGA_00085 1.6e-133 glpQ1_1 3.1.4.46 C Psort location Cytoplasmic, score 8.96
EIPGFFGA_00086 5.7e-105 3.1.4.46 C Psort location Cytoplasmic, score 8.96
EIPGFFGA_00087 1.5e-32 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EIPGFFGA_00088 9.6e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EIPGFFGA_00089 1.1e-86 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EIPGFFGA_00090 3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
EIPGFFGA_00091 4.3e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIPGFFGA_00092 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EIPGFFGA_00093 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EIPGFFGA_00094 3.9e-53 amt P Ammonium Transporter
EIPGFFGA_00095 1.8e-99 amt P Ammonium Transporter
EIPGFFGA_00096 1.9e-53 glnB K Belongs to the P(II) protein family
EIPGFFGA_00097 3.5e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
EIPGFFGA_00098 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EIPGFFGA_00099 8.6e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
EIPGFFGA_00100 1.5e-222 ytfP S Flavoprotein
EIPGFFGA_00101 6.3e-97 radC E Belongs to the UPF0758 family
EIPGFFGA_00102 1.7e-128 puuD T peptidase C26
EIPGFFGA_00103 2.1e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EIPGFFGA_00104 4.5e-222 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
EIPGFFGA_00106 3e-84 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EIPGFFGA_00107 1.1e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
EIPGFFGA_00108 2.9e-17 yjdB S Domain of unknown function (DUF4767)
EIPGFFGA_00109 2.3e-198 yyaQ S YjbR
EIPGFFGA_00110 2.6e-109 ccpA K Catabolite control protein A
EIPGFFGA_00111 1.3e-222 fasC 2.7.13.3 T protein histidine kinase activity
EIPGFFGA_00112 1.1e-306 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EIPGFFGA_00113 4.2e-167 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
EIPGFFGA_00114 7e-141 cppA E CppA N-terminal
EIPGFFGA_00115 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EIPGFFGA_00117 6.7e-93 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EIPGFFGA_00118 3e-221 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EIPGFFGA_00119 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
EIPGFFGA_00120 1.6e-144 XK27_08050 O HflC and HflK could regulate a protease
EIPGFFGA_00121 2.6e-28 MA20_06245 S yiaA/B two helix domain
EIPGFFGA_00122 2e-210 uup S abc transporter atp-binding protein
EIPGFFGA_00123 6e-303 dnaK O Heat shock 70 kDa protein
EIPGFFGA_00124 8.4e-34 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EIPGFFGA_00125 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
EIPGFFGA_00126 1.2e-82 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EIPGFFGA_00127 1.3e-156 yvgN C reductase
EIPGFFGA_00128 1.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EIPGFFGA_00129 3.7e-230 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EIPGFFGA_00130 3.8e-113 3.5.1.28 M domain protein
EIPGFFGA_00131 8.6e-113 3.5.1.28 M domain protein
EIPGFFGA_00132 1.6e-11 ycdA S Domain of unknown function (DUF4352)
EIPGFFGA_00133 3.2e-47 ybhL S Belongs to the BI1 family
EIPGFFGA_00134 1.6e-36 yneF S UPF0154 protein
EIPGFFGA_00135 1.6e-116 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EIPGFFGA_00136 1.6e-247 pbuO S permease
EIPGFFGA_00137 3.2e-98 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EIPGFFGA_00139 9.2e-21 S Domain of unknown function (DUF4767)
EIPGFFGA_00140 2.9e-81 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EIPGFFGA_00141 5.3e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
EIPGFFGA_00143 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
EIPGFFGA_00144 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
EIPGFFGA_00145 2.4e-184 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EIPGFFGA_00146 2.8e-123 XK27_09800 I Acyltransferase
EIPGFFGA_00147 1.6e-81 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EIPGFFGA_00148 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EIPGFFGA_00149 4.1e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EIPGFFGA_00150 2.2e-69 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EIPGFFGA_00151 4.3e-97 ytmP 2.7.1.89 M Phosphotransferase
EIPGFFGA_00152 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EIPGFFGA_00153 1.9e-88 L COG1943 Transposase and inactivated derivatives
EIPGFFGA_00154 1.3e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
EIPGFFGA_00155 2e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EIPGFFGA_00156 5.4e-61
EIPGFFGA_00157 1e-198 L Replication initiation factor
EIPGFFGA_00158 1.7e-43 yegQ O Peptidase U32
EIPGFFGA_00159 4.1e-223 yegQ O Peptidase U32
EIPGFFGA_00160 0.0 fruA 2.7.1.202 G phosphotransferase system
EIPGFFGA_00161 8.7e-164 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
EIPGFFGA_00162 2.3e-150 cobQ S glutamine amidotransferase
EIPGFFGA_00163 7.3e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
EIPGFFGA_00165 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
EIPGFFGA_00166 7.8e-152 XK27_08835 S ABC transporter substrate binding protein
EIPGFFGA_00167 4.1e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EIPGFFGA_00168 8.8e-43 gltJ P ABC transporter (Permease
EIPGFFGA_00169 1.4e-40 gltJ P ABC transporter (Permease
EIPGFFGA_00170 2.4e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EIPGFFGA_00171 6e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EIPGFFGA_00172 2.1e-55 cylA V abc transporter atp-binding protein
EIPGFFGA_00173 3.1e-129 cylB V ABC-2 type transporter
EIPGFFGA_00174 9e-75 K COG3279 Response regulator of the LytR AlgR family
EIPGFFGA_00175 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EIPGFFGA_00176 2.2e-21 I mechanosensitive ion channel activity
EIPGFFGA_00178 6.8e-72 copY K negative regulation of transcription, DNA-templated
EIPGFFGA_00179 1.4e-41 ylxQ J ribosomal protein
EIPGFFGA_00180 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
EIPGFFGA_00181 4.2e-22 nusA K Participates in both transcription termination and antitermination
EIPGFFGA_00182 4.3e-36 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EIPGFFGA_00183 4.2e-59 fruR K transcriptional
EIPGFFGA_00184 2.4e-95 S Carbohydrate-binding domain-containing protein Cthe_2159
EIPGFFGA_00186 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
EIPGFFGA_00187 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EIPGFFGA_00188 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
EIPGFFGA_00189 1.4e-57 asp S cog cog1302
EIPGFFGA_00190 1.5e-223 norN V Mate efflux family protein
EIPGFFGA_00191 4.3e-275 thrC 4.2.3.1 E Threonine synthase
EIPGFFGA_00194 1.6e-203 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EIPGFFGA_00195 4.3e-40 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EIPGFFGA_00196 1.5e-86 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EIPGFFGA_00197 1.1e-49 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EIPGFFGA_00199 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EIPGFFGA_00200 2.2e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EIPGFFGA_00202 6e-112 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EIPGFFGA_00203 2.9e-252 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EIPGFFGA_00204 1.6e-94 2.3.1.128 K acetyltransferase
EIPGFFGA_00205 4.4e-230 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EIPGFFGA_00206 7.5e-104 thiJ-2 3.5.1.124 S DJ-1/PfpI family
EIPGFFGA_00207 2.5e-124 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EIPGFFGA_00208 2.9e-161 acoA C Dehydrogenase E1 component
EIPGFFGA_00209 3.9e-12 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EIPGFFGA_00210 1.6e-46 K DNA-binding transcription factor activity
EIPGFFGA_00211 1.1e-21 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EIPGFFGA_00212 1.4e-98 yqeG S hydrolase of the HAD superfamily
EIPGFFGA_00213 7.7e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
EIPGFFGA_00214 1.5e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
EIPGFFGA_00215 4.8e-72 GM domain, Protein
EIPGFFGA_00216 2.7e-85 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EIPGFFGA_00217 3e-114 azlC E AzlC protein
EIPGFFGA_00218 3.7e-46 azlD S branched-chain amino acid
EIPGFFGA_00219 1.2e-172 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
EIPGFFGA_00220 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
EIPGFFGA_00221 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EIPGFFGA_00222 9.5e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EIPGFFGA_00223 1.2e-74 yjbK S Adenylate cyclase
EIPGFFGA_00224 1.4e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EIPGFFGA_00225 6.5e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
EIPGFFGA_00226 2.8e-31 ykuL S CBS domain
EIPGFFGA_00228 2.3e-96 typA T GTP-binding protein TypA
EIPGFFGA_00229 5.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EIPGFFGA_00230 2.2e-262 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EIPGFFGA_00231 6.8e-122 clcA P Chloride transporter, ClC family
EIPGFFGA_00233 9.5e-102 clcA_2 P Chloride transporter, ClC family
EIPGFFGA_00234 2.3e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
EIPGFFGA_00235 7.1e-153 higA K Pfam:DUF955
EIPGFFGA_00236 4.8e-15 higA K Pfam:DUF955
EIPGFFGA_00237 7.1e-275 argH 4.3.2.1 E Argininosuccinate lyase
EIPGFFGA_00238 9.3e-139 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EIPGFFGA_00239 4e-138 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EIPGFFGA_00240 1.2e-277 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EIPGFFGA_00241 5e-102 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIPGFFGA_00242 1.1e-93 sepF D cell septum assembly
EIPGFFGA_00243 3.8e-30 yggT D integral membrane protein
EIPGFFGA_00244 2.6e-145 5.1.3.2 GM Psort location CytoplasmicMembrane, score
EIPGFFGA_00245 4e-46 5.1.3.2 GM Psort location CytoplasmicMembrane, score
EIPGFFGA_00246 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EIPGFFGA_00247 3.9e-08 MU outer membrane autotransporter barrel domain protein
EIPGFFGA_00248 1.3e-168 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EIPGFFGA_00250 9e-101 srtB 3.4.22.70 S Sortase family
EIPGFFGA_00251 1.3e-190 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EIPGFFGA_00252 3.3e-95 XK27_09825 V abc transporter atp-binding protein
EIPGFFGA_00253 5.7e-119 yvfS V Transporter
EIPGFFGA_00255 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EIPGFFGA_00256 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EIPGFFGA_00257 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EIPGFFGA_00258 5.6e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EIPGFFGA_00259 4.3e-95 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EIPGFFGA_00260 7.2e-134 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EIPGFFGA_00261 1.1e-147 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EIPGFFGA_00262 1.7e-180 yufP S Belongs to the binding-protein-dependent transport system permease family
EIPGFFGA_00263 9.7e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EIPGFFGA_00264 2.4e-45 ftsL D cell division protein FtsL
EIPGFFGA_00265 1.9e-53 ftsI 3.4.16.4 M penicillin-binding protein
EIPGFFGA_00267 2.6e-121 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EIPGFFGA_00268 3e-84 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EIPGFFGA_00269 4.3e-139 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EIPGFFGA_00270 5.1e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EIPGFFGA_00271 1.2e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EIPGFFGA_00272 5.4e-156 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
EIPGFFGA_00273 5.1e-284 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EIPGFFGA_00274 6.2e-202 mloB K Transcriptional regulator
EIPGFFGA_00275 5.7e-173 ctpE P E1-E2 ATPase
EIPGFFGA_00276 3e-78 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
EIPGFFGA_00277 1.7e-117 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EIPGFFGA_00278 1.4e-107 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EIPGFFGA_00279 1.4e-141 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EIPGFFGA_00280 5.4e-11 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EIPGFFGA_00281 4.6e-98
EIPGFFGA_00282 3.6e-192 sbcC L ATPase involved in DNA repair
EIPGFFGA_00283 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EIPGFFGA_00284 1.2e-36 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EIPGFFGA_00285 8.2e-134 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EIPGFFGA_00286 6e-47 feoA P FeoA domain protein
EIPGFFGA_00287 9.3e-112 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EIPGFFGA_00288 2.4e-130 comEC S Competence protein ComEC
EIPGFFGA_00289 9.3e-156 XK27_03015 S permease
EIPGFFGA_00290 2.5e-258 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EIPGFFGA_00291 2.1e-111 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EIPGFFGA_00292 4.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EIPGFFGA_00293 5.7e-62 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EIPGFFGA_00294 4.1e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EIPGFFGA_00295 2.2e-63 S SseB protein N-terminal domain
EIPGFFGA_00296 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
EIPGFFGA_00297 2.8e-73 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
EIPGFFGA_00298 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EIPGFFGA_00299 1.8e-192 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EIPGFFGA_00300 2.6e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EIPGFFGA_00301 2.4e-166 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EIPGFFGA_00302 5.3e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIPGFFGA_00303 6e-32 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIPGFFGA_00304 2.3e-64 gtrA S GtrA-like protein
EIPGFFGA_00305 4e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
EIPGFFGA_00306 5.7e-163 ET ABC transporter substrate-binding protein
EIPGFFGA_00307 6.5e-104 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EIPGFFGA_00308 2.7e-25 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EIPGFFGA_00309 1.3e-125 amiA E ABC transporter, substrate-binding protein, family 5
EIPGFFGA_00310 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
EIPGFFGA_00311 4.8e-122 estA CE1 S Esterase
EIPGFFGA_00312 5.8e-200 iscS 2.8.1.7 E Cysteine desulfurase
EIPGFFGA_00314 2.2e-96 ytqB J (SAM)-dependent
EIPGFFGA_00315 5.2e-104 yhcC S radical SAM protein
EIPGFFGA_00316 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EIPGFFGA_00317 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EIPGFFGA_00318 1.9e-23 rpmD J ribosomal protein l30
EIPGFFGA_00319 3e-221 norM V Multidrug efflux pump
EIPGFFGA_00320 6.8e-133 ecsA_2 V abc transporter atp-binding protein
EIPGFFGA_00321 3.8e-163 rmuC S RmuC domain protein
EIPGFFGA_00322 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
EIPGFFGA_00323 8e-230 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
EIPGFFGA_00324 3.8e-32 V permease protein
EIPGFFGA_00325 3.9e-58 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EIPGFFGA_00326 7.9e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EIPGFFGA_00327 4.2e-53 yheA S Belongs to the UPF0342 family
EIPGFFGA_00328 7.2e-80 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EIPGFFGA_00329 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EIPGFFGA_00330 1.6e-73 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EIPGFFGA_00331 1.7e-72 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EIPGFFGA_00332 6.8e-116 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EIPGFFGA_00333 1.7e-73 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EIPGFFGA_00334 2.7e-71 lytE M LysM domain protein
EIPGFFGA_00335 8e-120 ecsA V abc transporter atp-binding protein
EIPGFFGA_00336 1.6e-202 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIPGFFGA_00337 1.1e-121 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EIPGFFGA_00339 5.4e-193 L Transposase IS116 IS110 IS902
EIPGFFGA_00340 1.2e-71 marR K Transcriptional regulator, MarR family
EIPGFFGA_00341 7.3e-25 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EIPGFFGA_00342 6e-74 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EIPGFFGA_00343 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
EIPGFFGA_00344 5.2e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EIPGFFGA_00345 5.2e-125 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EIPGFFGA_00346 7e-110 drgA C nitroreductase
EIPGFFGA_00347 1.5e-158 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EIPGFFGA_00348 1.9e-164 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EIPGFFGA_00349 1.2e-109 S dextransucrase activity
EIPGFFGA_00350 2.7e-147 EG Permeases of the drug metabolite transporter (DMT) superfamily
EIPGFFGA_00352 1.8e-237 amiA E ABC transporter, substrate-binding protein, family 5
EIPGFFGA_00353 1e-72 nusG K Participates in transcription elongation, termination and antitermination
EIPGFFGA_00355 2.4e-71 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIPGFFGA_00356 1.8e-135 S dextransucrase activity
EIPGFFGA_00358 6.5e-129 rpsA 1.17.7.4 J ribosomal protein S1
EIPGFFGA_00359 1.1e-167 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
EIPGFFGA_00360 5.2e-78 glcR K transcriptional regulator (DeoR family)
EIPGFFGA_00361 2.7e-146 cof S Sucrose-6F-phosphate phosphohydrolase
EIPGFFGA_00362 2e-83 XK27_07020 S Belongs to the UPF0371 family
EIPGFFGA_00363 3.9e-159 cobW S CobW P47K family protein
EIPGFFGA_00364 1.5e-150 yitS S EDD domain protein, DegV family
EIPGFFGA_00366 2.4e-87 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EIPGFFGA_00367 9.4e-37 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EIPGFFGA_00368 1e-79 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
EIPGFFGA_00369 1e-75 fld C Flavodoxin
EIPGFFGA_00370 1.6e-123 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EIPGFFGA_00371 1.6e-260 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EIPGFFGA_00372 5.4e-98 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EIPGFFGA_00373 5.9e-17 glk 2.7.1.2 G Glucokinase
EIPGFFGA_00374 6.2e-148 S Protein of unknown function (DUF3114)
EIPGFFGA_00376 1.2e-129 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EIPGFFGA_00377 9.1e-86 pscB M CHAP domain protein
EIPGFFGA_00378 2.1e-38 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EIPGFFGA_00379 9.2e-102 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EIPGFFGA_00380 8.7e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EIPGFFGA_00381 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
EIPGFFGA_00382 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EIPGFFGA_00383 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIPGFFGA_00384 3.4e-121 atpB C it plays a direct role in the translocation of protons across the membrane
EIPGFFGA_00385 9.5e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EIPGFFGA_00386 1.6e-70 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EIPGFFGA_00387 1.9e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EIPGFFGA_00388 1.6e-143 tatD L Hydrolase, tatd
EIPGFFGA_00389 4.1e-52 S Domain of unknown function (DUF4300)
EIPGFFGA_00390 6.6e-123 V CAAX protease self-immunity
EIPGFFGA_00391 9.8e-21 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EIPGFFGA_00392 1.6e-93 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EIPGFFGA_00393 5.1e-119 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
EIPGFFGA_00395 6.2e-202 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EIPGFFGA_00396 4.1e-18 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EIPGFFGA_00397 1.1e-164 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EIPGFFGA_00398 3.8e-129 rgpF GT2,GT4 M Glycosyltransferase like family 2
EIPGFFGA_00399 1.9e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EIPGFFGA_00400 7.7e-210 S phospholipase Carboxylesterase
EIPGFFGA_00401 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EIPGFFGA_00402 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EIPGFFGA_00403 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EIPGFFGA_00404 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EIPGFFGA_00405 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EIPGFFGA_00406 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EIPGFFGA_00407 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EIPGFFGA_00408 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
EIPGFFGA_00409 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EIPGFFGA_00410 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EIPGFFGA_00411 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EIPGFFGA_00412 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EIPGFFGA_00413 1.5e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EIPGFFGA_00414 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EIPGFFGA_00415 1.3e-103 rplD J Forms part of the polypeptide exit tunnel
EIPGFFGA_00416 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EIPGFFGA_00417 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
EIPGFFGA_00418 9.1e-189 XK27_05470 E Methionine synthase
EIPGFFGA_00419 3.4e-21 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EIPGFFGA_00420 4.6e-12 folE 3.5.4.16 F gtp cyclohydrolase
EIPGFFGA_00421 3.8e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EIPGFFGA_00422 5.8e-51 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EIPGFFGA_00423 5.4e-84 S membrane
EIPGFFGA_00424 7.6e-36 P VTC domain
EIPGFFGA_00425 1.5e-138 msmX P Belongs to the ABC transporter superfamily
EIPGFFGA_00426 3.6e-160 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EIPGFFGA_00427 8.4e-165 cpsY K Transcriptional regulator
EIPGFFGA_00430 1.9e-95 ywlG S Belongs to the UPF0340 family
EIPGFFGA_00431 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EIPGFFGA_00432 1.2e-36 2.7.6.5 S Region found in RelA / SpoT proteins
EIPGFFGA_00433 2.9e-117 T response regulator
EIPGFFGA_00435 2e-144 XK27_09825 V 'abc transporter, ATP-binding protein
EIPGFFGA_00436 1.9e-118 pepV 3.5.1.18 E Dipeptidase
EIPGFFGA_00437 3.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
EIPGFFGA_00438 5.1e-31 K transcriptional regulator
EIPGFFGA_00439 6.9e-192 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EIPGFFGA_00441 3.9e-51 L Transposase
EIPGFFGA_00442 3.5e-137 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
EIPGFFGA_00443 2.6e-70 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EIPGFFGA_00444 5.3e-193 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EIPGFFGA_00445 1.9e-65 bcrA V abc transporter atp-binding protein
EIPGFFGA_00446 1.2e-124 S ABC-2 family transporter protein
EIPGFFGA_00447 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIPGFFGA_00448 3.6e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EIPGFFGA_00449 1.6e-27 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EIPGFFGA_00450 4.6e-169 ftsI 3.4.16.4 M penicillin-binding protein
EIPGFFGA_00452 1.2e-41 cdsA 2.7.7.41 S Belongs to the CDS family
EIPGFFGA_00453 6.5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EIPGFFGA_00454 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EIPGFFGA_00455 2.8e-308 WQ51_06230 S ABC transporter
EIPGFFGA_00456 2e-14 WQ51_06230 S ABC transporter
EIPGFFGA_00457 1.4e-142 cmpC S abc transporter atp-binding protein
EIPGFFGA_00458 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EIPGFFGA_00459 1.5e-59 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EIPGFFGA_00460 2.6e-144 desK 2.7.13.3 T Histidine kinase
EIPGFFGA_00461 6.7e-113 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EIPGFFGA_00462 3.7e-199 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
EIPGFFGA_00463 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
EIPGFFGA_00464 5.2e-75 S oxidoreductase
EIPGFFGA_00465 5.5e-217 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EIPGFFGA_00466 3.8e-182 L the current gene model (or a revised gene model) may contain a
EIPGFFGA_00467 9.1e-53 vraS 2.7.13.3 T Histidine kinase
EIPGFFGA_00468 4.3e-83 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EIPGFFGA_00469 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EIPGFFGA_00470 7.4e-35 rlpA M LysM domain protein
EIPGFFGA_00471 3.2e-228 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
EIPGFFGA_00473 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
EIPGFFGA_00474 2.5e-98 mdlA V abc transporter atp-binding protein
EIPGFFGA_00475 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EIPGFFGA_00476 2.3e-47 supH S overlaps another CDS with the same product name
EIPGFFGA_00477 7.1e-147 XK27_02985 S overlaps another CDS with the same product name
EIPGFFGA_00478 3.3e-200 yurR 1.4.5.1 E oxidoreductase
EIPGFFGA_00479 1.9e-169 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EIPGFFGA_00480 5.1e-21 sumf2 S PEGA domain
EIPGFFGA_00481 1.7e-131 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EIPGFFGA_00482 4.2e-187 ylbL T Belongs to the peptidase S16 family
EIPGFFGA_00483 6e-17 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EIPGFFGA_00484 4e-30 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
EIPGFFGA_00485 5.8e-24 U response to pH
EIPGFFGA_00486 1.1e-107 yfmR S abc transporter atp-binding protein
EIPGFFGA_00487 1.3e-129 livH E Belongs to the binding-protein-dependent transport system permease family
EIPGFFGA_00489 4.6e-120 ydaO E amino acid
EIPGFFGA_00490 2.6e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EIPGFFGA_00491 1.2e-47
EIPGFFGA_00492 4.8e-42
EIPGFFGA_00493 3.1e-197 yceA S Belongs to the UPF0176 family
EIPGFFGA_00494 8.5e-193 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EIPGFFGA_00495 2e-136 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
EIPGFFGA_00496 1.2e-17 S Protein of unknown function (DUF3021)
EIPGFFGA_00497 2.5e-50 L transposase and inactivated derivatives, IS30 family
EIPGFFGA_00498 1.8e-104 L Integrase
EIPGFFGA_00499 1.1e-25 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EIPGFFGA_00500 1.6e-85 manL 2.7.1.191 G pts system
EIPGFFGA_00501 4.6e-97 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EIPGFFGA_00502 1.6e-122 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIPGFFGA_00505 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EIPGFFGA_00506 1.9e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EIPGFFGA_00508 3.5e-99 V CAAX protease self-immunity
EIPGFFGA_00509 4.4e-58 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EIPGFFGA_00510 3e-14 coiA 3.6.4.12 S Competence protein
EIPGFFGA_00511 1.2e-13
EIPGFFGA_00512 4.9e-103 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
EIPGFFGA_00513 3.2e-44 yrzB S Belongs to the UPF0473 family
EIPGFFGA_00514 7.3e-33 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EIPGFFGA_00515 1.6e-19 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EIPGFFGA_00516 6.3e-44 yrzL S Belongs to the UPF0297 family
EIPGFFGA_00517 1.3e-81 Z012_10770 M Domain of unknown function (DUF1919)
EIPGFFGA_00518 1.4e-189 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EIPGFFGA_00519 8.7e-75 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIPGFFGA_00520 1.4e-87 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EIPGFFGA_00521 1.4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
EIPGFFGA_00522 6.1e-56 3.5.1.28 M domain protein
EIPGFFGA_00523 1.8e-42 htpX O Belongs to the peptidase M48B family
EIPGFFGA_00524 5e-119 sirR K iron dependent repressor
EIPGFFGA_00525 4.4e-90 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EIPGFFGA_00526 4.6e-59 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EIPGFFGA_00527 4.4e-32 ftsE D cell division ATP-binding protein FtsE
EIPGFFGA_00528 8.4e-198 glf 5.4.99.9 M UDP-galactopyranose mutase
EIPGFFGA_00529 4.1e-59 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
EIPGFFGA_00530 2.6e-74 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EIPGFFGA_00531 1.2e-206 2.7.13.3 T GHKL domain
EIPGFFGA_00532 5.2e-119 yqfA K protein, Hemolysin III
EIPGFFGA_00533 4.1e-29 pspC KT PspC domain protein
EIPGFFGA_00534 5.1e-55 yaaT S stage 0 sporulation protein
EIPGFFGA_00535 1.2e-54 yabA L Involved in initiation control of chromosome replication
EIPGFFGA_00537 1.7e-24 I acyl-CoA dehydrogenase
EIPGFFGA_00538 7.4e-137 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIPGFFGA_00539 1.2e-79 glnA 6.3.1.2 E glutamine synthetase
EIPGFFGA_00540 6.2e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EIPGFFGA_00542 2.4e-30 yozG K Transcriptional regulator
EIPGFFGA_00544 4.4e-147 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EIPGFFGA_00545 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EIPGFFGA_00546 3.9e-67 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EIPGFFGA_00547 7.7e-55 pelF GT4 M Domain of unknown function (DUF3492)
EIPGFFGA_00548 1.8e-75 pelF GT4 M Domain of unknown function (DUF3492)
EIPGFFGA_00549 6.4e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EIPGFFGA_00550 1.7e-44 K WHG domain
EIPGFFGA_00551 5.1e-45 V abc transporter atp-binding protein
EIPGFFGA_00552 1.6e-64 V abc transporter atp-binding protein
EIPGFFGA_00553 1.6e-29
EIPGFFGA_00555 1.1e-49
EIPGFFGA_00556 2e-146 murB 1.3.1.98 M cell wall formation
EIPGFFGA_00557 2.2e-108 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EIPGFFGA_00559 8.4e-70 K LytTr DNA-binding domain
EIPGFFGA_00560 1.2e-79 S Protein of unknown function (DUF3021)
EIPGFFGA_00561 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EIPGFFGA_00562 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EIPGFFGA_00563 6.9e-69 argR K Regulates arginine biosynthesis genes
EIPGFFGA_00564 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EIPGFFGA_00565 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EIPGFFGA_00566 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EIPGFFGA_00567 2.9e-134 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EIPGFFGA_00568 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EIPGFFGA_00569 7.9e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EIPGFFGA_00570 1.2e-45 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
EIPGFFGA_00571 1.6e-97 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EIPGFFGA_00572 2.4e-102 T Histidine kinase
EIPGFFGA_00574 1.4e-16 csbD S CsbD-like
EIPGFFGA_00575 8.2e-73 S Protein of unknown function (DUF421)
EIPGFFGA_00577 3.5e-74 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
EIPGFFGA_00578 1.2e-103 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EIPGFFGA_00579 2.2e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EIPGFFGA_00580 5.9e-52 U protein secretion
EIPGFFGA_00581 8e-112 lrgB M cytolysis
EIPGFFGA_00582 2.6e-65 M Pfam SNARE associated Golgi protein
EIPGFFGA_00584 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EIPGFFGA_00585 1e-35 XK27_05110 P chloride
EIPGFFGA_00586 8.6e-93 udk 2.7.1.48 F Cytidine monophosphokinase
EIPGFFGA_00587 7.9e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
EIPGFFGA_00588 5.7e-197 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EIPGFFGA_00589 7e-192 rgpF GT2,GT4 M Glycosyltransferase like family 2
EIPGFFGA_00590 2.1e-32 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EIPGFFGA_00591 9.1e-19 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EIPGFFGA_00592 5.3e-74 L Transposase
EIPGFFGA_00593 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EIPGFFGA_00594 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EIPGFFGA_00595 5.9e-67 manO S Protein conserved in bacteria
EIPGFFGA_00596 3.5e-83 manN G PTS system mannose fructose sorbose family IID component
EIPGFFGA_00597 2.9e-179 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EIPGFFGA_00598 2.9e-47 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EIPGFFGA_00599 1.5e-97 XK27_09740 S Phosphoesterase
EIPGFFGA_00600 2.4e-73 soj1 D chromosome partitioning
EIPGFFGA_00601 1.4e-151 S COG1073 Hydrolases of the alpha beta superfamily
EIPGFFGA_00602 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EIPGFFGA_00603 7.4e-92 cvpA S toxin biosynthetic process
EIPGFFGA_00604 6.5e-54 3.1.3.18 S IA, variant 1
EIPGFFGA_00605 7.2e-148 yeiH S Psort location CytoplasmicMembrane, score 10.00
EIPGFFGA_00606 2.7e-169 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EIPGFFGA_00607 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EIPGFFGA_00608 5.1e-72 prkC 2.7.11.1 KLT serine threonine protein kinase
EIPGFFGA_00609 1.5e-141 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EIPGFFGA_00610 3.1e-107 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EIPGFFGA_00611 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EIPGFFGA_00612 7.2e-101 S AAA domain, putative AbiEii toxin, Type IV TA system
EIPGFFGA_00613 3e-63 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EIPGFFGA_00614 5.2e-31 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EIPGFFGA_00615 1.8e-87 yvqF S Membrane
EIPGFFGA_00616 1e-54 metB 2.5.1.48, 4.4.1.8 E cystathionine
EIPGFFGA_00617 5.8e-49
EIPGFFGA_00618 8.5e-78 K TetR family transcriptional regulator
EIPGFFGA_00619 1.9e-143 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EIPGFFGA_00620 1.8e-53 hpk9 2.7.13.3 T protein histidine kinase activity
EIPGFFGA_00621 6.2e-67 hpk9 2.7.13.3 T protein histidine kinase activity
EIPGFFGA_00622 2.3e-111 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EIPGFFGA_00623 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EIPGFFGA_00624 7.7e-92 lemA S LemA family
EIPGFFGA_00625 8.4e-182 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EIPGFFGA_00626 3.9e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
EIPGFFGA_00627 3.6e-49 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EIPGFFGA_00628 3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EIPGFFGA_00629 5.3e-167 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIPGFFGA_00630 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
EIPGFFGA_00631 4.4e-52
EIPGFFGA_00633 3.9e-27 yqeB S Pyrimidine dimer DNA glycosylase
EIPGFFGA_00634 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EIPGFFGA_00635 1.3e-15 citZ 2.3.3.1 C Belongs to the citrate synthase family
EIPGFFGA_00636 2.1e-151 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EIPGFFGA_00637 1e-84 endA F DNA RNA non-specific endonuclease
EIPGFFGA_00638 1e-54 tcyB_2 P ABC transporter (permease)
EIPGFFGA_00639 1.7e-41 L Phage integrase, N-terminal SAM-like domain
EIPGFFGA_00640 6.2e-120 yoaK S Protein of unknown function (DUF1275)
EIPGFFGA_00642 2.6e-166 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EIPGFFGA_00643 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EIPGFFGA_00644 4.1e-07
EIPGFFGA_00645 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EIPGFFGA_00646 1.6e-24 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EIPGFFGA_00647 2.9e-168 corA P COG0598 Mg2 and Co2 transporters
EIPGFFGA_00648 1e-19 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EIPGFFGA_00649 4.9e-102 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EIPGFFGA_00650 2e-155 pstS P phosphate
EIPGFFGA_00651 5.6e-172 adhP 1.1.1.1 C alcohol dehydrogenase
EIPGFFGA_00652 2.5e-33 S Domain of unknown function (DUF5123)
EIPGFFGA_00653 1.2e-132 lmrA V abc transporter atp-binding protein
EIPGFFGA_00654 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIPGFFGA_00658 1.4e-47 L PFAM Integrase, catalytic core
EIPGFFGA_00659 2.6e-73 L PFAM Integrase, catalytic core
EIPGFFGA_00660 4e-34 rpsJ J Involved in the binding of tRNA to the ribosomes
EIPGFFGA_00661 2.3e-51 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EIPGFFGA_00662 3.3e-26 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EIPGFFGA_00663 7.9e-56 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EIPGFFGA_00664 4.2e-28 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EIPGFFGA_00665 1.9e-46 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
EIPGFFGA_00666 6.7e-45 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EIPGFFGA_00667 1e-96 hscC O Belongs to the heat shock protein 70 family
EIPGFFGA_00669 1.6e-169 pyrP F uracil Permease
EIPGFFGA_00670 5.7e-50 XK27_01300 S ASCH
EIPGFFGA_00671 6e-93 leuS 6.1.1.4 J Leucyl-tRNA synthetase, Domain 2
EIPGFFGA_00672 5.5e-24 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIPGFFGA_00673 3.6e-79 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIPGFFGA_00674 1.7e-156 6.3.2.2 H gamma-glutamylcysteine synthetase
EIPGFFGA_00675 4.4e-214 amiC P ABC transporter (Permease
EIPGFFGA_00676 3.8e-165 amiD P ABC transporter (Permease
EIPGFFGA_00677 7.9e-202 oppD P Belongs to the ABC transporter superfamily
EIPGFFGA_00678 3.3e-172 oppF P Belongs to the ABC transporter superfamily
EIPGFFGA_00679 3.2e-128 V Psort location CytoplasmicMembrane, score
EIPGFFGA_00680 3.5e-118 skfE V abc transporter atp-binding protein
EIPGFFGA_00681 2.8e-45 yvoA_1 K Transcriptional
EIPGFFGA_00682 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
EIPGFFGA_00683 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EIPGFFGA_00684 2.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
EIPGFFGA_00685 8.7e-129 adcB P ABC transporter (Permease
EIPGFFGA_00686 9.2e-135 adcC P ABC transporter, ATP-binding protein
EIPGFFGA_00687 2.3e-298 O MreB/Mbl protein
EIPGFFGA_00689 5.8e-146 V Psort location CytoplasmicMembrane, score
EIPGFFGA_00693 8.9e-14
EIPGFFGA_00694 1.2e-120 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EIPGFFGA_00695 7.3e-150 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EIPGFFGA_00696 8.5e-43 comGC U Required for transformation and DNA binding
EIPGFFGA_00697 8.4e-70 cglD NU Competence protein
EIPGFFGA_00698 3.1e-15 NU Type II secretory pathway pseudopilin
EIPGFFGA_00699 4.5e-71 comGF U Competence protein ComGF
EIPGFFGA_00700 2e-12 comGF U Putative Competence protein ComGF
EIPGFFGA_00701 1.1e-175 ytxK 2.1.1.72 L DNA methylase
EIPGFFGA_00702 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EIPGFFGA_00703 3.8e-110 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIPGFFGA_00704 5.9e-82 nrdI F Belongs to the NrdI family
EIPGFFGA_00705 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EIPGFFGA_00706 1.4e-30 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EIPGFFGA_00707 1.6e-52 K transcriptional regulator, PadR family
EIPGFFGA_00708 1e-70 XK27_06920 S Protein of unknown function (DUF1700)
EIPGFFGA_00709 2.2e-106 S Putative adhesin
EIPGFFGA_00710 1.6e-159 XK27_06930 V domain protein
EIPGFFGA_00711 9.9e-97 XK27_06935 K transcriptional regulator
EIPGFFGA_00712 5e-45 ypaA M Membrane
EIPGFFGA_00713 1.7e-117 S CAAX protease self-immunity
EIPGFFGA_00714 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EIPGFFGA_00715 7.6e-09 S NTF2 fold immunity protein
EIPGFFGA_00716 5.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EIPGFFGA_00717 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
EIPGFFGA_00718 1.1e-198 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EIPGFFGA_00719 1.1e-113 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EIPGFFGA_00720 1.1e-23 S CAAX amino terminal protease family protein
EIPGFFGA_00721 1e-268 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EIPGFFGA_00722 2.2e-73 rplI J binds to the 23S rRNA
EIPGFFGA_00723 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EIPGFFGA_00724 1.8e-47 veg S Biofilm formation stimulator VEG
EIPGFFGA_00725 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EIPGFFGA_00726 1.9e-10
EIPGFFGA_00727 7.5e-14
EIPGFFGA_00728 1.6e-88 XK27_10930 K acetyltransferase
EIPGFFGA_00729 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EIPGFFGA_00730 4e-122 yaaA S Belongs to the UPF0246 family
EIPGFFGA_00731 9.3e-167 XK27_01785 S cog cog1284
EIPGFFGA_00732 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EIPGFFGA_00733 1.8e-19 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIPGFFGA_00734 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIPGFFGA_00736 3.6e-137 cbf S 3'-5' exoribonuclease yhaM
EIPGFFGA_00737 6.9e-142 purR 2.4.2.7 F operon repressor
EIPGFFGA_00738 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EIPGFFGA_00739 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EIPGFFGA_00740 7.3e-33 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EIPGFFGA_00741 3.3e-33 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EIPGFFGA_00742 1.6e-28 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EIPGFFGA_00743 2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EIPGFFGA_00744 3.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EIPGFFGA_00745 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EIPGFFGA_00746 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EIPGFFGA_00747 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EIPGFFGA_00748 1.5e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EIPGFFGA_00749 5.3e-275 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EIPGFFGA_00750 8.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
EIPGFFGA_00751 0.0 S Bacterial membrane protein, YfhO
EIPGFFGA_00752 9.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EIPGFFGA_00753 5.4e-99 yvbG U UPF0056 membrane protein
EIPGFFGA_00754 3.1e-41 yaaA S S4 domain protein YaaA
EIPGFFGA_00755 5.7e-200 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EIPGFFGA_00756 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EIPGFFGA_00757 4.5e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EIPGFFGA_00758 2.7e-249 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EIPGFFGA_00759 1.1e-142 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EIPGFFGA_00760 3.6e-94 dnaQ 2.7.7.7 L DNA polymerase III
EIPGFFGA_00761 1.4e-125 K transcriptional regulator, MerR family
EIPGFFGA_00762 0.0 V ABC transporter (Permease
EIPGFFGA_00763 6.9e-19 V abc transporter atp-binding protein
EIPGFFGA_00764 5.4e-93 asp1 S Accessory Sec system protein Asp1
EIPGFFGA_00765 4.7e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
EIPGFFGA_00766 0.0 M family 8
EIPGFFGA_00767 1.7e-19 M family 8
EIPGFFGA_00768 1.5e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EIPGFFGA_00769 1.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EIPGFFGA_00770 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EIPGFFGA_00771 1.6e-102 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EIPGFFGA_00772 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EIPGFFGA_00773 1.8e-125 IQ reductase
EIPGFFGA_00774 3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EIPGFFGA_00775 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
EIPGFFGA_00776 1.8e-105 artQ P ABC transporter (Permease
EIPGFFGA_00777 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
EIPGFFGA_00778 4.6e-157 aatB ET ABC transporter substrate-binding protein
EIPGFFGA_00779 3.7e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIPGFFGA_00780 1.8e-38 gcvR T UPF0237 protein
EIPGFFGA_00781 6.6e-243 XK27_08635 S UPF0210 protein
EIPGFFGA_00782 6.2e-131 ais G Phosphoglycerate mutase
EIPGFFGA_00783 5.3e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EIPGFFGA_00784 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
EIPGFFGA_00785 5.4e-129 S sequence-specific DNA binding
EIPGFFGA_00786 3.5e-233 ymfH S Peptidase M16
EIPGFFGA_00787 9.3e-231 ymfF S Peptidase M16
EIPGFFGA_00788 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EIPGFFGA_00792 3.3e-155 rrmA 2.1.1.187 Q methyltransferase
EIPGFFGA_00793 2.6e-135 S HAD hydrolase, family IA, variant
EIPGFFGA_00794 2.6e-106 K transcriptional regulator (lysR family)
EIPGFFGA_00795 9.8e-64 S reductase
EIPGFFGA_00796 4.6e-74 S reductase
EIPGFFGA_00797 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIPGFFGA_00798 2.5e-62 manO S protein conserved in bacteria
EIPGFFGA_00799 2.3e-156 manN G PTS system mannose fructose sorbose family IID component
EIPGFFGA_00800 2e-117 manM G pts system
EIPGFFGA_00801 3.1e-173 manL 2.7.1.191 G pts system
EIPGFFGA_00802 0.0 pepF E oligoendopeptidase F
EIPGFFGA_00803 6.4e-131 coiA 3.6.4.12 S Competence protein
EIPGFFGA_00804 7.5e-175 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EIPGFFGA_00805 1.2e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EIPGFFGA_00806 1.3e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EIPGFFGA_00807 1.2e-183 tcsA S membrane
EIPGFFGA_00808 4.5e-152 degV S DegV family
EIPGFFGA_00809 6e-91 yacP S RNA-binding protein containing a PIN domain
EIPGFFGA_00810 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIPGFFGA_00812 3.4e-179 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
EIPGFFGA_00813 1.4e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EIPGFFGA_00814 2.1e-238 purD 6.3.4.13 F Belongs to the GARS family
EIPGFFGA_00815 3.3e-155 S CHAP domain
EIPGFFGA_00816 4.3e-200 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EIPGFFGA_00817 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EIPGFFGA_00818 7.7e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EIPGFFGA_00819 2e-115 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EIPGFFGA_00820 7.7e-163 ywbD 2.1.1.191 J Methyltransferase
EIPGFFGA_00821 6.3e-199 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EIPGFFGA_00822 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
EIPGFFGA_00823 4.8e-210 lysC 2.7.2.4 E Belongs to the aspartokinase family
EIPGFFGA_00824 7.6e-178 jag S RNA-binding protein
EIPGFFGA_00825 9.9e-98 K Transcriptional regulator
EIPGFFGA_00826 4.2e-98 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
EIPGFFGA_00827 3.4e-14 rpmH J Ribosomal protein L34
EIPGFFGA_00828 4.4e-155 V ABC transporter
EIPGFFGA_00829 6.1e-126 yeeN K transcriptional regulatory protein
EIPGFFGA_00830 8.5e-46 yajC U protein transport
EIPGFFGA_00831 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EIPGFFGA_00832 9.9e-280 ybiT S abc transporter atp-binding protein
EIPGFFGA_00833 1.1e-64 xth 3.1.11.2 L exodeoxyribonuclease III
EIPGFFGA_00834 1.7e-71 S QueT transporter
EIPGFFGA_00836 2.1e-111 yfjR K regulation of single-species biofilm formation
EIPGFFGA_00837 1e-207 ccs S the current gene model (or a revised gene model) may contain a frame shift
EIPGFFGA_00838 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EIPGFFGA_00839 4e-181 S Protein of unknown function (DUF3114)
EIPGFFGA_00840 1.3e-140 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EIPGFFGA_00841 4.5e-293 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EIPGFFGA_00842 9.3e-231 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EIPGFFGA_00843 1.5e-36 ylqC L Belongs to the UPF0109 family
EIPGFFGA_00844 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EIPGFFGA_00846 4.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EIPGFFGA_00847 2.6e-209 macB_2 V FtsX-like permease family
EIPGFFGA_00848 6.7e-104 nodB3 G deacetylase
EIPGFFGA_00849 3.5e-140 yabB 2.1.1.223 L Methyltransferase
EIPGFFGA_00850 6.6e-41 yazA L endonuclease containing a URI domain
EIPGFFGA_00851 1.9e-244 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EIPGFFGA_00852 5.8e-112 yrrM 2.1.1.104 S O-Methyltransferase
EIPGFFGA_00853 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
EIPGFFGA_00854 3e-84 yxjI S LURP-one-related
EIPGFFGA_00855 8.4e-94 F Shikimate kinase
EIPGFFGA_00856 7.6e-55 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
EIPGFFGA_00857 3.3e-101 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
EIPGFFGA_00858 2e-92 S UPF0397 protein
EIPGFFGA_00859 1.9e-308 ykoD P abc transporter atp-binding protein
EIPGFFGA_00861 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EIPGFFGA_00862 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
EIPGFFGA_00863 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EIPGFFGA_00864 1.6e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
EIPGFFGA_00865 1e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EIPGFFGA_00866 2e-144 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EIPGFFGA_00867 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EIPGFFGA_00868 4.7e-49 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
EIPGFFGA_00869 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
EIPGFFGA_00870 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
EIPGFFGA_00871 1.6e-293 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EIPGFFGA_00872 2.8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EIPGFFGA_00873 1.2e-233 sufD O assembly protein SufD
EIPGFFGA_00874 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EIPGFFGA_00875 9.4e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
EIPGFFGA_00876 5.2e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EIPGFFGA_00877 9.6e-23
EIPGFFGA_00878 5.3e-44 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EIPGFFGA_00879 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EIPGFFGA_00880 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EIPGFFGA_00881 7.9e-97 XK27_08585 S Psort location CytoplasmicMembrane, score
EIPGFFGA_00882 4.4e-55 fnt P Formate nitrite transporter
EIPGFFGA_00884 4.7e-168 fhuR K transcriptional regulator (lysR family)
EIPGFFGA_00885 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EIPGFFGA_00886 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EIPGFFGA_00887 4.6e-157 yjjH S Calcineurin-like phosphoesterase
EIPGFFGA_00888 4.5e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EIPGFFGA_00889 4.3e-68 pacL 3.6.3.8 P cation transport ATPase
EIPGFFGA_00890 1.3e-196 pepO 3.4.24.71 O Peptidase family M13
EIPGFFGA_00891 1.1e-29 yyzM S Protein conserved in bacteria
EIPGFFGA_00892 6.2e-195 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EIPGFFGA_00893 1.3e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EIPGFFGA_00894 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
EIPGFFGA_00895 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
EIPGFFGA_00896 1.7e-17 XK27_00735
EIPGFFGA_00897 9.8e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
EIPGFFGA_00898 1.3e-231 U protein secretion
EIPGFFGA_00899 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EIPGFFGA_00900 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EIPGFFGA_00901 3.4e-221 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EIPGFFGA_00902 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EIPGFFGA_00903 7.2e-161 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EIPGFFGA_00904 2.8e-222 yfiB1 V abc transporter atp-binding protein
EIPGFFGA_00905 0.0 XK27_10035 V abc transporter atp-binding protein
EIPGFFGA_00906 2.7e-161 ypuA S secreted protein
EIPGFFGA_00907 3.7e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
EIPGFFGA_00908 8.8e-84 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
EIPGFFGA_00909 5.3e-84 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EIPGFFGA_00910 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EIPGFFGA_00911 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
EIPGFFGA_00912 3.4e-250 trkH P Cation transport protein
EIPGFFGA_00913 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EIPGFFGA_00914 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EIPGFFGA_00915 5.7e-112
EIPGFFGA_00916 7.6e-140 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EIPGFFGA_00917 4.8e-51 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EIPGFFGA_00918 3.3e-198 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EIPGFFGA_00919 8.2e-67 ctsR K Belongs to the CtsR family
EIPGFFGA_00920 0.0 clpC O Belongs to the ClpA ClpB family
EIPGFFGA_00921 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EIPGFFGA_00922 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EIPGFFGA_00923 1e-162 rapZ S Displays ATPase and GTPase activities
EIPGFFGA_00924 5e-134 yejC S cyclic nucleotide-binding protein
EIPGFFGA_00925 3.2e-65 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EIPGFFGA_00926 2.6e-14 S Domain of unknown function (DUF3173)
EIPGFFGA_00927 3.5e-142
EIPGFFGA_00928 9.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EIPGFFGA_00929 6.2e-230 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EIPGFFGA_00930 5.4e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
EIPGFFGA_00931 2.4e-225 rgpA GT4 M Domain of unknown function (DUF1972)
EIPGFFGA_00932 7.7e-274 ywbL P COG0672 High-affinity Fe2 Pb2 permease
EIPGFFGA_00933 9.7e-22
EIPGFFGA_00934 5.8e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EIPGFFGA_00935 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EIPGFFGA_00936 6.9e-248 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EIPGFFGA_00937 1.7e-63 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EIPGFFGA_00938 7e-56 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
EIPGFFGA_00939 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
EIPGFFGA_00940 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EIPGFFGA_00941 2.3e-63 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EIPGFFGA_00942 6.3e-70 M Pilin isopeptide linkage domain protein
EIPGFFGA_00943 2.4e-172 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EIPGFFGA_00944 2.6e-121 macB V ABC transporter, ATP-binding protein
EIPGFFGA_00945 9.1e-178 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIPGFFGA_00946 7.6e-98 2.1.1.223 S Putative SAM-dependent methyltransferase
EIPGFFGA_00947 4.3e-80 rimP S Required for maturation of 30S ribosomal subunits
EIPGFFGA_00948 2e-188 brpA K Transcriptional
EIPGFFGA_00949 1.3e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
EIPGFFGA_00950 2.6e-65 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EIPGFFGA_00951 5.1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
EIPGFFGA_00952 8.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EIPGFFGA_00953 1.1e-147 cinA 3.5.1.42 S Belongs to the CinA family
EIPGFFGA_00954 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EIPGFFGA_00955 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
EIPGFFGA_00956 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
EIPGFFGA_00957 1.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
EIPGFFGA_00958 1.8e-150 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EIPGFFGA_00959 2.7e-26
EIPGFFGA_00960 2.9e-273 sufB O assembly protein SufB
EIPGFFGA_00961 1.1e-30 nifU C SUF system FeS assembly protein, NifU family
EIPGFFGA_00962 2.1e-200 2.7.13.3 T protein histidine kinase activity
EIPGFFGA_00963 5.9e-112 serB 3.1.3.3 E phosphoserine phosphatase
EIPGFFGA_00964 1.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EIPGFFGA_00965 2.7e-29 K sequence-specific DNA binding
EIPGFFGA_00966 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EIPGFFGA_00967 1.9e-83 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EIPGFFGA_00968 1.9e-80 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EIPGFFGA_00969 1.3e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EIPGFFGA_00970 2.5e-80 yjbM 2.7.6.5 S Gtp pyrophosphokinase
EIPGFFGA_00971 8.4e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EIPGFFGA_00972 8.7e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIPGFFGA_00973 5.1e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EIPGFFGA_00974 1.3e-69 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EIPGFFGA_00975 1.3e-73 XK27_02470 K LytTr DNA-binding domain
EIPGFFGA_00976 5.3e-119 liaI S membrane
EIPGFFGA_00977 2.9e-193 mccF V LD-carboxypeptidase
EIPGFFGA_00978 2.8e-109
EIPGFFGA_00979 1.8e-276 L DNA integration
EIPGFFGA_00980 2.7e-302 yhgF K Transcriptional accessory protein
EIPGFFGA_00981 3.9e-83 ydcK S Belongs to the SprT family
EIPGFFGA_00982 2.2e-41 pspC KT PspC domain
EIPGFFGA_00983 5.7e-104 estA E Lysophospholipase L1 and related esterases
EIPGFFGA_00984 1e-201 S unusual protein kinase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)