ORF_ID e_value Gene_name EC_number CAZy COGs Description
AIIGCJOP_00002 2.6e-18 csgA S major curlin subunit
AIIGCJOP_00003 2.7e-49 csgC O Curli assembly protein
AIIGCJOP_00004 3e-18
AIIGCJOP_00005 6.9e-82 ymdB S Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation
AIIGCJOP_00006 1.2e-242 clsC 2.7.8.8 I COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes
AIIGCJOP_00007 5.3e-204 mdoC I Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane
AIIGCJOP_00008 5.2e-300 mdoG P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AIIGCJOP_00009 0.0 mdoH GT2 M Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AIIGCJOP_00010 6.4e-37 yceK S (Lipo)protein
AIIGCJOP_00011 7e-65 msyB S SecY secA suppressor protein
AIIGCJOP_00012 5.4e-204 mdtG EGP Major facilitator Superfamily
AIIGCJOP_00013 1.6e-171 lpxL 2.3.1.241, 2.3.1.242, 2.3.1.243 M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)
AIIGCJOP_00014 7.1e-192 yceA S Belongs to the UPF0176 family
AIIGCJOP_00015 7.1e-101 yceI S Belongs to the UPF0312 family
AIIGCJOP_00016 7.6e-95 yceJ C cytochrome b561
AIIGCJOP_00017 1.8e-07 S Protein of unknown function (DUF2770)
AIIGCJOP_00018 2.2e-215 solA 1.5.3.1 E Belongs to the MSOX MTOX family. MTOX subfamily
AIIGCJOP_00019 4e-40 bssS S disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
AIIGCJOP_00020 1.7e-35 dinI S SOS response
AIIGCJOP_00021 3.1e-195 pyrC 3.5.2.3 F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate
AIIGCJOP_00022 9.7e-95 yceB S Lipoprotein
AIIGCJOP_00023 1.4e-215 mdtH U Multidrug resistance protein mdtH
AIIGCJOP_00024 9.1e-112 rimJ 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AIIGCJOP_00025 5.3e-105 yceH S Belongs to the UPF0502 family
AIIGCJOP_00026 2.9e-165 mviM 1.1.1.18, 1.1.1.369 S oxidoreductase
AIIGCJOP_00027 9.2e-273 murJ S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
AIIGCJOP_00028 2.1e-62 flgN N Flagellar biosynthesis protein
AIIGCJOP_00029 5.4e-33 flgM KNU Anti-sigma-28 factor FlgM
AIIGCJOP_00030 1.2e-101 flgA N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AIIGCJOP_00031 2.4e-66 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
AIIGCJOP_00032 4.1e-63 flgC N Belongs to the flagella basal body rod proteins family
AIIGCJOP_00033 4.8e-99 flgD N Required for flagellar hook formation. May act as a scaffolding protein
AIIGCJOP_00034 6.3e-219 flgE N Flagellar hook protein flgE
AIIGCJOP_00035 1.2e-129 flgF N flagellar basal body
AIIGCJOP_00036 4e-139 flgG N Belongs to the flagella basal body rod proteins family
AIIGCJOP_00037 3e-122 flgH N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AIIGCJOP_00038 1.6e-186 flgI N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AIIGCJOP_00039 7e-170 flgJ 3.5.1.28 N Flagellar rod assembly protein muramidase FlgJ
AIIGCJOP_00040 2.4e-274 flgK N flagellar hook-associated protein
AIIGCJOP_00041 3.3e-151 flgL N Belongs to the bacterial flagellin family
AIIGCJOP_00042 1.3e-149 ynfM_3 EGP Major facilitator Superfamily
AIIGCJOP_00043 1.2e-158 ttdR K transcriptional regulator
AIIGCJOP_00044 0.0 rne 3.1.26.12 J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs
AIIGCJOP_00045 9.1e-167 rluC 5.4.99.24 J Responsible for synthesis of pseudouridine from uracil
AIIGCJOP_00046 4.8e-105 maf 1.1.1.25, 2.1.1.190 D Maf-like protein
AIIGCJOP_00047 3.9e-90 yceD S metal-binding, possibly nucleic acid-binding protein
AIIGCJOP_00048 2.8e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AIIGCJOP_00049 4.9e-137 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AIIGCJOP_00050 5.2e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AIIGCJOP_00051 3e-165 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AIIGCJOP_00052 7.6e-124 IQ reductase
AIIGCJOP_00053 8.9e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AIIGCJOP_00054 4.3e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AIIGCJOP_00055 1.8e-126 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
AIIGCJOP_00056 2.4e-184 mltG F Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AIIGCJOP_00057 7.4e-107 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AIIGCJOP_00058 7.8e-180 holB 2.7.7.7 L dna polymerase iii
AIIGCJOP_00059 2.8e-148 ycfH L TatD family
AIIGCJOP_00060 5.1e-265 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system, glucose-specific IIBC subunit
AIIGCJOP_00061 0.0 fhuE P receptor
AIIGCJOP_00062 1.3e-60 hinT FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AIIGCJOP_00063 2.3e-38 ycfL S cellular response to DNA damage stimulus
AIIGCJOP_00064 3.2e-89 lpoB M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AIIGCJOP_00065 2.6e-136 thiK 2.7.1.89 M Catalyzes the phosphorylation of thiamine to thiamine phosphate
AIIGCJOP_00066 9.4e-189 nagZ 2.7.8.7, 3.2.1.21, 3.2.1.52 GH3 G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides
AIIGCJOP_00067 1.3e-104 ycfP S Belongs to the UPF0227 family
AIIGCJOP_00068 2.5e-239 ndh 1.6.99.3 C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase
AIIGCJOP_00069 5.3e-66 ycfJ S Outer Membrane Lipoprotein
AIIGCJOP_00070 1.7e-108 ycfQ K Transcriptional regulator
AIIGCJOP_00071 1.7e-33 bhsA S Protein of unknown function (DUF1471)
AIIGCJOP_00072 9.1e-170 ycfS M ErfK YbiS YcfS YnhG family protein
AIIGCJOP_00073 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AIIGCJOP_00074 2.8e-191 ycfT S Acyltransferase
AIIGCJOP_00075 6e-192 lolC M Lipoprotein releasing system transmembrane protein
AIIGCJOP_00076 5e-125 lolD V Part of the ABC transporter complex LolCDE involved in the translocation of
AIIGCJOP_00077 1.3e-213 lolE M Lipoprotein releasing system transmembrane protein
AIIGCJOP_00078 4.6e-171 nagK 2.7.1.4, 2.7.1.59 F Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P
AIIGCJOP_00079 1.6e-138 cobB K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AIIGCJOP_00082 2.4e-192 potD P Required for the activity of the bacterial periplasmic transport system of putrescine
AIIGCJOP_00083 7.6e-130 potC P ABC-type spermidine putrescine transport system, permease component II
AIIGCJOP_00084 3.3e-147 potB P ABC-type spermidine putrescine transport system, permease component I
AIIGCJOP_00085 1.8e-209 potA 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AIIGCJOP_00086 1.7e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AIIGCJOP_00087 1.5e-216 ycfD 1.14.11.47 S Cupin 4 family protein
AIIGCJOP_00088 2.8e-255 T PhoQ Sensor
AIIGCJOP_00089 5.5e-121 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_00090 4.2e-261 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AIIGCJOP_00091 1.8e-105 hflD 4.3.2.2 S High frequency lysogenization protein hflD homolog
AIIGCJOP_00092 1.6e-213 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AIIGCJOP_00093 3.8e-84 nudJ L Belongs to the Nudix hydrolase family. NudJ subfamily
AIIGCJOP_00094 5.9e-107 rluE 5.4.99.19, 5.4.99.20, 5.4.99.22 J RNA pseudouridylate synthase
AIIGCJOP_00095 3.4e-241 icd 1.1.1.42 C Isocitrate dehydrogenase
AIIGCJOP_00096 1.2e-31
AIIGCJOP_00098 5.3e-37 yeaQ S transglycosylase associated protein
AIIGCJOP_00099 1.7e-07 yoaK
AIIGCJOP_00100 1.5e-47 yeaP 2.7.7.65 T Diguanylate cyclase
AIIGCJOP_00101 4.9e-86 yeaP 2.7.7.65 T Diguanylate cyclase with GAF sensor
AIIGCJOP_00102 9.7e-49
AIIGCJOP_00103 2.2e-49 yeaO S MarR family transcriptional regulator
AIIGCJOP_00104 7.6e-121 pyrG2 6.3.4.2 F CTP synthase
AIIGCJOP_00105 2.1e-200 yeaN P Major facilitator superfamily
AIIGCJOP_00106 4.6e-135 yeaM K Transcriptional regulator
AIIGCJOP_00107 6.6e-70 yeaL S UPF0756 membrane protein
AIIGCJOP_00108 0.0 oprC P Receptor
AIIGCJOP_00109 1.3e-225 yhbH S Belongs to the UPF0229 family
AIIGCJOP_00110 0.0 prkA T Serine Protein Kinase
AIIGCJOP_00111 5.3e-141 mipA M MltA-interacting protein
AIIGCJOP_00112 8.2e-146 yeaE 1.1.1.21 S Aldo keto
AIIGCJOP_00113 3.7e-165 yeaD 4.2.1.9, 5.1.3.15 G Belongs to the glucose-6-phosphate 1-epimerase family
AIIGCJOP_00114 2.1e-185 gapA 1.2.1.12, 1.2.1.72 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AIIGCJOP_00115 9.1e-74 msrB 1.8.4.12 C methionine sulfoxide reductase
AIIGCJOP_00116 6.8e-41 yeaC S protein conserved in bacteria
AIIGCJOP_00117 7.9e-222 chiA1 3.2.1.14 GH18 M Glyco_18
AIIGCJOP_00118 7.1e-118 pncA 2.7.11.1, 3.5.1.19 Q Nicotinamidase
AIIGCJOP_00119 1.9e-189 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
AIIGCJOP_00120 0.0 sppA OU Signal peptide peptidase
AIIGCJOP_00121 1e-96 ydjA C Nitroreductase
AIIGCJOP_00122 6.4e-193 selD 2.7.9.3 F Synthesizes selenophosphate from selenide and ATP
AIIGCJOP_00123 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AIIGCJOP_00124 2.1e-249 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
AIIGCJOP_00125 3.5e-45 ynjH S Protein of unknown function (DUF1496)
AIIGCJOP_00126 4.3e-63 nudG 3.6.1.55, 3.6.1.65 L belongs to the nudix hydrolase family
AIIGCJOP_00127 3.1e-88 ynjA S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AIIGCJOP_00128 1.8e-105 ynjF 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AIIGCJOP_00129 6.9e-237 ynjE 2.8.1.11 M sulfurtransferase
AIIGCJOP_00130 3.1e-97 ynjD S ABC transporter
AIIGCJOP_00131 3.9e-247 ynjC P transport system permease component
AIIGCJOP_00132 5.9e-211 ynjB S transport system periplasmic component
AIIGCJOP_00133 1.1e-100 merA M Pfam SNARE associated Golgi protein
AIIGCJOP_00134 2.5e-153 xthA 3.1.11.2 L Exodeoxyribonuclease III
AIIGCJOP_00135 2.2e-229 argD 2.6.1.11, 2.6.1.17, 2.6.1.81 E aminotransferase
AIIGCJOP_00136 2.9e-193 astA 1.2.1.71, 2.3.1.109 E arginine N-succinyltransferase
AIIGCJOP_00137 7.3e-275 astD 1.2.1.71 C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate
AIIGCJOP_00138 4.6e-236 astB 3.5.3.23 E Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)
AIIGCJOP_00139 3.1e-173 astE 3.5.1.96 E Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily
AIIGCJOP_00140 1.1e-70 spy NPTU Heavy-metal resistance
AIIGCJOP_00141 1.5e-100 ves S Belongs to the Ves family
AIIGCJOP_00142 1.7e-162 cho 2.7.7.7 L Nuclease subunit of the excinuclease complex
AIIGCJOP_00143 2.2e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AIIGCJOP_00144 1.4e-56 osmE J activator of ntr-like gene protein
AIIGCJOP_00145 7.7e-49 chbB 2.7.1.196, 2.7.1.205 G protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar
AIIGCJOP_00146 7.5e-226 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AIIGCJOP_00147 6e-50 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase System
AIIGCJOP_00148 1.3e-151 chbR K transcriptional regulator
AIIGCJOP_00149 1.5e-258 chbF 3.2.1.86 GT4 G Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate
AIIGCJOP_00150 2.4e-125 chbG 2.7.1.196, 2.7.1.205, 3.5.1.105 G Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF
AIIGCJOP_00151 0.0 katE 1.11.1.6 C serves to protect cells from the toxic effects of hydrogen peroxide
AIIGCJOP_00152 3.9e-37 cedA D Activates the cell division inhibited by chromosomal DNA over-replication
AIIGCJOP_00153 7.2e-216 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AIIGCJOP_00154 3.7e-113 ydjM S membrane-bound metal-dependent
AIIGCJOP_00155 4.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AIIGCJOP_00156 1.7e-114 yniC 3.1.3.23 S HAD-superfamily hydrolase subfamily IA, variant 3
AIIGCJOP_00157 3.9e-85 yniB S Membrane
AIIGCJOP_00158 1.5e-166 yniA G Fructosamine kinase
AIIGCJOP_00159 1.2e-40 ydiZ S endoribonuclease activity
AIIGCJOP_00160 1.7e-160 pfkB 2.7.1.11, 2.7.1.56 H belongs to the carbohydrate kinase PfkB family
AIIGCJOP_00161 1.9e-133 ydiY M Protein of unknown function, DUF481
AIIGCJOP_00162 2.3e-29
AIIGCJOP_00163 9.1e-10
AIIGCJOP_00164 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AIIGCJOP_00165 3e-54 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AIIGCJOP_00166 9.5e-29 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AIIGCJOP_00167 2.4e-54 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AIIGCJOP_00168 5.1e-184 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AIIGCJOP_00169 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AIIGCJOP_00170 1.4e-47 himA K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
AIIGCJOP_00171 3.5e-148 btuC H Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane
AIIGCJOP_00172 8.7e-31 S membrane
AIIGCJOP_00173 1.3e-149 gtrB GT2 M Bactoprenol glucosyl transferase
AIIGCJOP_00174 7.8e-89 btuE 1.11.1.9 C Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent
AIIGCJOP_00175 6.6e-115 btuD 3.6.3.33 P Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AIIGCJOP_00176 6.8e-78 nlpC 3.4.17.13 M NlpC/P60 family
AIIGCJOP_00177 8.2e-107 ydiV 3.1.4.52 T Diguanylate phosphodiesterase
AIIGCJOP_00178 1.9e-275 ydiU S Belongs to the UPF0061 (SELO) family
AIIGCJOP_00179 1e-22 hemP P Hemin uptake protein
AIIGCJOP_00180 9.6e-197 aroH 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AIIGCJOP_00181 2.7e-149 ydiA 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation
AIIGCJOP_00182 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
AIIGCJOP_00183 8.5e-249 G Symporter
AIIGCJOP_00184 0.0 bxlA 3.2.1.21 GH3 G Fibronectin type III-like domain
AIIGCJOP_00188 3.3e-179 ydiK S ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated
AIIGCJOP_00189 0.0 ydiJ C Fad linked oxidase
AIIGCJOP_00190 1.5e-68 menI 3.1.2.28 Q Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA)
AIIGCJOP_00192 2.3e-76 arcR T Winged helix-turn-helix DNA binding
AIIGCJOP_00193 4.6e-80 arcR T Winged helix-turn-helix DNA binding
AIIGCJOP_00194 2.1e-59 sfaG NU Fimbrial protein
AIIGCJOP_00195 1.6e-75 M Pili assembly chaperone PapD, C-terminal domain
AIIGCJOP_00196 0.0 NU Usher protein
AIIGCJOP_00197 1.2e-50 NU Fimbrial protein
AIIGCJOP_00198 1.5e-46 NU Fimbrial protein
AIIGCJOP_00199 9.1e-41 rcsB_2 K LuxR family transcriptional regulator
AIIGCJOP_00200 7.3e-59 sufA S Iron-sulphur cluster biosynthesis
AIIGCJOP_00201 6.6e-292 sufB O FeS assembly protein SufB
AIIGCJOP_00202 7.5e-135 sufC O FeS assembly ATPase SufC
AIIGCJOP_00203 1e-221 sufD O FeS assembly protein SufD
AIIGCJOP_00204 2.9e-221 sufS 2.8.1.7, 4.4.1.16 E Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo
AIIGCJOP_00205 7.5e-68 sufE 2.8.1.7, 4.4.1.16 S Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process
AIIGCJOP_00206 1.1e-168 ycfS M ErfK YbiS YcfS YnhG family protein
AIIGCJOP_00207 2.2e-16 lpp M major outer membrane lipoprotein
AIIGCJOP_00208 3.5e-258 pyk 2.7.1.40, 2.7.7.4 G Pyruvate kinase
AIIGCJOP_00209 2.6e-183 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AIIGCJOP_00210 9.7e-110 metI P PFAM binding-protein-dependent transport systems inner membrane component
AIIGCJOP_00211 2.6e-149 metQ P Belongs to the NlpA lipoprotein family
AIIGCJOP_00212 3.4e-29 ydhZ S Protein of unknown function (DUF2767)
AIIGCJOP_00213 5.9e-102 glnP P PFAM binding-protein-dependent transport systems inner membrane component
AIIGCJOP_00214 2.9e-110 glnM P polar amino acid ABC transporter, inner membrane subunit
AIIGCJOP_00215 2.7e-114 glnQ 3.6.3.21 E ABC transporter
AIIGCJOP_00216 9.3e-131 fliY_2 ET belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_00217 4.4e-16
AIIGCJOP_00218 5.4e-213 fixL 2.7.13.3 T Signal transduction histidine kinase
AIIGCJOP_00219 5.4e-99 fixJ K response regulator
AIIGCJOP_00220 1.1e-73 S Haem-degrading
AIIGCJOP_00221 4.5e-17
AIIGCJOP_00222 2.4e-131 ymaE S Metallo-beta-lactamase superfamily
AIIGCJOP_00223 2.3e-113 cynT 4.2.1.1 P Reversible hydration of carbon dioxide
AIIGCJOP_00224 4.5e-219 G 3-hydroxyanthranilate 3,4-dioxygenase activity
AIIGCJOP_00225 3e-134 garL 4.1.2.20, 4.1.2.52 G Belongs to the HpcH HpaI aldolase family
AIIGCJOP_00226 2.4e-98 1.11.1.10, 3.1.1.24 E hydrolases or acyltransferases, alpha beta hydrolase superfamily
AIIGCJOP_00227 6.9e-112 IQ Enoyl-(Acyl carrier protein) reductase
AIIGCJOP_00228 8.9e-240 hisD2 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AIIGCJOP_00229 2.4e-210 EGP Major facilitator Superfamily
AIIGCJOP_00230 2.1e-183 K transcriptional regulator
AIIGCJOP_00231 9.3e-178 S SnoaL-like polyketide cyclase
AIIGCJOP_00232 8.2e-226 S SnoaL-like polyketide cyclase
AIIGCJOP_00233 2.8e-230 hisD_3 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AIIGCJOP_00234 3.3e-178 J Belongs to the amidase family
AIIGCJOP_00235 8.5e-253 ydhS S FAD-NAD(P)-binding
AIIGCJOP_00238 1.8e-232 mdtK P Multidrug efflux pump that functions probably as a Na( ) drug antiporter
AIIGCJOP_00239 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
AIIGCJOP_00240 5.9e-224 cfa 2.1.1.317, 2.1.1.79 M synthase
AIIGCJOP_00241 8.1e-200 ydhC EGP Major facilitator Superfamily
AIIGCJOP_00242 1.1e-175 ydhB K Transcriptional regulator
AIIGCJOP_00243 4.5e-191 purR K Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression
AIIGCJOP_00245 2.2e-194 ydhP EGP Major facilitator Superfamily
AIIGCJOP_00246 4.1e-104 sodB 1.15.1.1, 3.1.11.6 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AIIGCJOP_00247 1.1e-94 ydhO 3.2.1.14, 3.4.17.13 GH18 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
AIIGCJOP_00248 1.3e-60 grxD C Belongs to the glutaredoxin family. Monothiol subfamily
AIIGCJOP_00249 4.5e-120 rnt L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis
AIIGCJOP_00250 9.2e-71 gloA 4.4.1.5 H Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione
AIIGCJOP_00251 1.6e-202 nemA C nadh flavin
AIIGCJOP_00252 1.2e-89 nemR K transcriptional regulator
AIIGCJOP_00253 1.4e-287 eptA 2.7.8.42, 2.7.8.43 S membrane-associated metal-dependent hydrolase
AIIGCJOP_00254 1.1e-161 ydhF S Aldo Keto reductase
AIIGCJOP_00255 1.1e-89 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AIIGCJOP_00256 4.4e-150 ydhK S Fusaric acid resistance protein
AIIGCJOP_00257 9.1e-196 ydhK S Fusaric acid resistance
AIIGCJOP_00258 2.9e-129 ydhJ V Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AIIGCJOP_00259 6.4e-32 ydhI S Protein of unknown function (DUF1656)
AIIGCJOP_00260 3.2e-69 slyA K Transcription regulator that can specifically activate or repress expression of target genes
AIIGCJOP_00261 9.2e-192 T Diguanylate cyclase
AIIGCJOP_00262 6e-50 slyB M Outer Membrane Lipoprotein
AIIGCJOP_00263 5.1e-212 anmK 2.7.1.170, 4.2.1.126 F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AIIGCJOP_00264 8.1e-54 mliC S membrane-bound lysozyme inhibitor of c-type lysozyme
AIIGCJOP_00265 4.1e-121 pdxH 1.4.3.5 H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
AIIGCJOP_00266 7.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AIIGCJOP_00267 7.2e-158 pdxY 2.7.1.35 H Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AIIGCJOP_00268 4.8e-108 gst 2.5.1.18 O Belongs to the GST superfamily
AIIGCJOP_00269 6.9e-273 dtpA U Proton-dependent permease that transports di- and tripeptides
AIIGCJOP_00270 3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AIIGCJOP_00271 1.7e-101 rnfE 2.3.1.243, 4.2.99.18 C Part of a membrane complex involved in electron transport
AIIGCJOP_00272 2.4e-102 rnfG C Part of a membrane complex involved in electron transport
AIIGCJOP_00273 1.1e-192 rnfD 1.6.5.8 C Part of a membrane complex involved in electron transport
AIIGCJOP_00274 7.3e-263 rnfC C Part of a membrane complex involved in electron transport
AIIGCJOP_00275 6.9e-88 rnfB 1.12.98.1 C Part of a membrane complex involved in electron transport
AIIGCJOP_00276 1.3e-94 rnfA C Part of a membrane complex involved in electron transport
AIIGCJOP_00277 5.5e-69 ydgK S Membrane
AIIGCJOP_00278 2.6e-32 cnu S expression modulating family protein
AIIGCJOP_00279 7.1e-21 blr
AIIGCJOP_00280 4.9e-201 ydgJ 1.1.1.371 S oxidoreductase
AIIGCJOP_00281 4.3e-178 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AIIGCJOP_00282 1.7e-210 malY 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AIIGCJOP_00283 4.9e-293 malX 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system
AIIGCJOP_00284 2.8e-180 malI K Periplasmic binding protein LacI transcriptional regulator
AIIGCJOP_00285 1.5e-89 K LysR substrate binding domain
AIIGCJOP_00286 1.2e-113 ytnP S Metallo-beta-lactamase superfamily
AIIGCJOP_00287 8.5e-143 S alpha/beta hydrolase fold
AIIGCJOP_00288 8.5e-258 ydgA S protein conserved in bacteria
AIIGCJOP_00289 6.1e-208 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G Belongs to the mannose-6-phosphate isomerase type 1 family
AIIGCJOP_00290 0.0 fumA 4.2.1.2 C Catalyzes the reversible hydration of fumarate to (S)- malate
AIIGCJOP_00291 2.8e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AIIGCJOP_00292 1.1e-167 tus L Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence
AIIGCJOP_00293 2.5e-234 T PhoQ Sensor
AIIGCJOP_00294 7.7e-119 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
AIIGCJOP_00295 1.7e-153 U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AIIGCJOP_00296 3e-163 P ABC transporter substrate-binding protein
AIIGCJOP_00297 6.4e-126 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_00298 1.3e-49 ydgC S GlpM family
AIIGCJOP_00299 2.1e-126 IQ reductase
AIIGCJOP_00300 1.4e-243 ydgI E Arginine ornithine antiporter
AIIGCJOP_00301 4.7e-158 ydgH S Protein of unknown function (DUF1471)
AIIGCJOP_00302 2.2e-266 pntA 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AIIGCJOP_00303 5.4e-248 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AIIGCJOP_00304 8.4e-191 mscS M mechanosensitive ion channel
AIIGCJOP_00305 3.7e-179 uspE T universal stress protein
AIIGCJOP_00306 1.9e-138 fnr K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AIIGCJOP_00307 4.4e-94 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AIIGCJOP_00308 2.7e-264 abgT H AbgT putative transporter family
AIIGCJOP_00309 4.3e-264 abgB 3.5.1.32 S amidohydrolase
AIIGCJOP_00310 2.3e-232 abgA 3.5.1.32 S Protein involved in hydrolase activity and metabolic process
AIIGCJOP_00311 5.5e-156 abgR K transcriptional regulator
AIIGCJOP_00312 1.2e-92 ydaL S protein conserved in bacteria
AIIGCJOP_00313 5.5e-143 qor 1.6.5.5 C alcohol dehydrogenase
AIIGCJOP_00314 3.3e-125 tqsA T permease
AIIGCJOP_00315 3.1e-46 mdtJ P Catalyzes the excretion of spermidine
AIIGCJOP_00316 9.5e-50 mdtI P Catalyzes the excretion of spermidine
AIIGCJOP_00317 0.0 T Diguanylate cyclase
AIIGCJOP_00318 8.5e-140 ydgD M Belongs to the peptidase S1B family
AIIGCJOP_00320 1.6e-282 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AIIGCJOP_00321 3e-221 ynfM EGP Major facilitator Superfamily
AIIGCJOP_00322 3e-154 ynfL K transcriptional regulator
AIIGCJOP_00323 8.5e-221 mlc GK Mlc, controls the expression of genes involved in the phosphotransferase and phosphoenolpyruvate systems, regulates genes involved in the uptake of sugars
AIIGCJOP_00324 1.7e-120 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AIIGCJOP_00325 3.2e-218 clcB P Voltage gated chloride channel
AIIGCJOP_00326 1e-212 opuCA E abc transporter atp-binding protein
AIIGCJOP_00327 5.7e-107 opuCB P Binding-protein-dependent transport system inner membrane component
AIIGCJOP_00328 1.9e-161 opuCC M Glycine betaine
AIIGCJOP_00329 7.9e-118 IV02_19100 P Binding-protein-dependent transport system inner membrane component
AIIGCJOP_00330 5e-115 S Protein of unknown function (DUF1275)
AIIGCJOP_00331 2.5e-115 gst8 2.5.1.18 O Glutathione S-Transferase
AIIGCJOP_00332 2.1e-132 K DJ-1/PfpI family
AIIGCJOP_00333 1.9e-102 S Phosphohydrolase
AIIGCJOP_00334 1.4e-135 K Transcriptional regulator
AIIGCJOP_00335 2.7e-147 K Transcriptional regulator
AIIGCJOP_00336 1.6e-159 S Dienelactone hydrolase family
AIIGCJOP_00337 5.5e-117 IQ oxidoreductase activity
AIIGCJOP_00339 2.2e-26
AIIGCJOP_00340 2.4e-213 merA 1.16.1.1, 1.8.1.7 C E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex
AIIGCJOP_00341 5.9e-143 tp53I3 C Alcohol dehydrogenase zinc-binding domain protein
AIIGCJOP_00342 7.8e-159 cinB I Alpha beta hydrolase
AIIGCJOP_00343 5.1e-129 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_00344 6.8e-149 K DJ-1/PfpI family
AIIGCJOP_00345 2.8e-168 opdE EGP Major facilitator superfamily
AIIGCJOP_00346 1.2e-191 S X-Pro dipeptidyl-peptidase (S15 family)
AIIGCJOP_00347 2e-150 K LysR substrate binding domain
AIIGCJOP_00348 5.2e-54
AIIGCJOP_00349 1.1e-64 S membrane
AIIGCJOP_00350 2.4e-34 msgA S DinI-like family
AIIGCJOP_00351 1.4e-94 2.7.1.89 M Phosphotransferase enzyme family
AIIGCJOP_00352 0.0 iutA H Receptor
AIIGCJOP_00353 1.9e-180 EGP Major facilitator Superfamily
AIIGCJOP_00354 5.3e-128 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_00355 8.8e-08 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_00356 1.8e-157 K DJ-1/PfpI family
AIIGCJOP_00358 1.3e-163 K LysR family transcriptional regulator
AIIGCJOP_00360 9.9e-81 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AIIGCJOP_00361 4.2e-64 S Domain of unknown function (DUF4142)
AIIGCJOP_00362 1.7e-188 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
AIIGCJOP_00363 5.4e-139 tauC P ABC-type nitrate sulfonate bicarbonate transport system permease component
AIIGCJOP_00364 8.3e-137 cysA_3 P ABC-type nitrate sulfonate bicarbonate transport system ATPase component
AIIGCJOP_00365 2.1e-126 IV02_09290 P Urea carboxylase-associated protein 2
AIIGCJOP_00366 1.7e-119 ycgI S urea carboxylase-associated protein 1
AIIGCJOP_00367 0.0 uca 6.3.4.14, 6.3.4.6, 6.4.1.2 EI Biotin carboxylase
AIIGCJOP_00368 0.0 atzF 3.5.1.4, 3.5.1.54 J Allophanate hydrolase
AIIGCJOP_00369 9e-99 dmsD S Required for biogenesis assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein
AIIGCJOP_00370 0.0 ynfE 1.8.5.3, 1.97.1.9 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_00371 3.6e-51 ynfD S membrane
AIIGCJOP_00372 1.8e-111 ynfC M Uncharacterised protein family (UPF0257)
AIIGCJOP_00373 2.3e-49 ynfB S Belongs to the UPF0482 family
AIIGCJOP_00374 1.7e-51 ynfA S UPF0060 membrane protein
AIIGCJOP_00375 1.7e-245 rspA 4.2.1.8 M Belongs to the mandelate racemase muconate lactonizing enzyme family
AIIGCJOP_00376 5.9e-175 rspB 1.1.1.380 C Dehydrogenase
AIIGCJOP_00377 8.9e-245 L Belongs to the 'phage' integrase family
AIIGCJOP_00378 1.4e-40 S Putative excisionase (DUF1233)
AIIGCJOP_00379 4.8e-35 S Protein involved in biological_process
AIIGCJOP_00380 1.2e-21
AIIGCJOP_00381 5.1e-38
AIIGCJOP_00382 6.9e-201 STY2074 S RecT family
AIIGCJOP_00383 0.0 2.7.7.7 L Enterobacterial exodeoxyribonuclease VIII
AIIGCJOP_00384 1.2e-18
AIIGCJOP_00385 3.4e-29
AIIGCJOP_00386 2.7e-17
AIIGCJOP_00387 4.1e-14
AIIGCJOP_00388 5.9e-65 K Helix-turn-helix
AIIGCJOP_00389 4.1e-33 S Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT
AIIGCJOP_00390 6e-84 S Putative bacterial toxin ydaT
AIIGCJOP_00391 1.8e-125 S Protein involved in DNA replication initiation, regulation of DNA replication, viral process and DNA replication
AIIGCJOP_00392 5.4e-125 dnaC L DNA replication protein
AIIGCJOP_00393 2.4e-40 glpR GK Bacterial protein of unknown function (DUF977)
AIIGCJOP_00394 2e-18
AIIGCJOP_00396 2.2e-07 Q methyltransferase
AIIGCJOP_00397 3.2e-64 V HNH endonuclease
AIIGCJOP_00399 3.2e-15
AIIGCJOP_00400 3.1e-99 S Protein of unknown function (DUF1367)
AIIGCJOP_00401 7e-22
AIIGCJOP_00402 2.4e-42
AIIGCJOP_00403 5.3e-52 J Cold shock protein domain
AIIGCJOP_00404 1.5e-15 ylcG
AIIGCJOP_00405 1.3e-140 O Antitermination protein
AIIGCJOP_00406 4.9e-27
AIIGCJOP_00408 9.7e-30 essD S Bacteriophage P21 holin S
AIIGCJOP_00409 3.6e-81 S Phage lysozyme
AIIGCJOP_00410 2.8e-48
AIIGCJOP_00411 5.3e-23
AIIGCJOP_00412 2.9e-94 xtmA L terminase, small subunit
AIIGCJOP_00413 0.0 S phage Terminase large subunit
AIIGCJOP_00414 2.7e-263 S Domain of unknown function (DUF4055)
AIIGCJOP_00415 4.1e-206 S Head morphogenesis protein
AIIGCJOP_00417 8.9e-120
AIIGCJOP_00418 3.2e-206 S P22 coat protein - gene protein 5
AIIGCJOP_00419 4.1e-15
AIIGCJOP_00420 2.8e-82
AIIGCJOP_00421 1.8e-54
AIIGCJOP_00422 4.6e-103
AIIGCJOP_00423 4.5e-74 S Bacteriophage related domain of unknown function
AIIGCJOP_00424 1.5e-161 BB2227 N Phage tail tube protein, TTP
AIIGCJOP_00425 4e-51 S Phage tail assembly chaperone
AIIGCJOP_00426 1.2e-45 S Phage related hypothetical protein (DUF1799)
AIIGCJOP_00427 0.0 sca1 D tail length tape measure
AIIGCJOP_00429 2.2e-52 S minor tail family protein
AIIGCJOP_00430 4.8e-137 L S Phage minor tail protein L
AIIGCJOP_00431 3.7e-139 3.5.1.28 M NLP P60 protein
AIIGCJOP_00432 1.9e-96 S virus tail assembly
AIIGCJOP_00433 0.0 NT Phage-related protein, tail component
AIIGCJOP_00434 2.2e-57 NT transmembrane signaling receptor activity
AIIGCJOP_00436 2.9e-41 S peptidoglycan catabolic process
AIIGCJOP_00437 1.9e-23
AIIGCJOP_00438 7.2e-47
AIIGCJOP_00441 1.2e-217 ydfJ EGP Major facilitator superfamily
AIIGCJOP_00442 7.7e-243 uxuT G MFS/sugar transport protein
AIIGCJOP_00443 2.2e-252 mtlK 1.1.1.11, 1.1.1.17, 1.1.1.289, 1.1.1.57, 1.1.1.58, 1.1.1.67, 2.7.1.17 G Belongs to the mannitol dehydrogenase family
AIIGCJOP_00444 5.3e-119 ydfH K transcriptional regulator
AIIGCJOP_00445 1.8e-136 ydfG 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_00446 0.0 dcp 3.4.15.5, 3.4.24.70 E PFAM peptidase M3A and M3B, thimet oligopeptidase F
AIIGCJOP_00447 1.1e-19 L Belongs to the 'phage' integrase family
AIIGCJOP_00449 3.3e-47
AIIGCJOP_00450 8e-210 yxjG 2.1.1.14 E methionine synthase
AIIGCJOP_00451 1.7e-240 urtA E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
AIIGCJOP_00452 4.4e-262 urtB E Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_00453 1.7e-188 urtC E Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_00454 5e-137 urtD E abc transporter atp-binding protein
AIIGCJOP_00455 4e-122 urtE E ABC transporter ATP-binding protein
AIIGCJOP_00456 2.8e-114 adcA S periplasmic or secreted protein
AIIGCJOP_00457 2.6e-206 ydeE EGP Major facilitator Superfamily
AIIGCJOP_00458 3e-138 eamA EG of the drug metabolite transporter (DMT) superfamily
AIIGCJOP_00459 3e-28 marB S Multiple antibiotic resistance
AIIGCJOP_00460 7.6e-67 marA K Transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype
AIIGCJOP_00461 1.8e-72 marR K transcriptional regulator
AIIGCJOP_00462 2.5e-102 marC U UPF0056 membrane protein
AIIGCJOP_00463 1.8e-191 sotB EGP Major facilitator Superfamily
AIIGCJOP_00464 9.9e-138 S Phenazine biosynthesis-like protein
AIIGCJOP_00465 2.5e-144 yddE S phenazine biosynthesis protein PhzF
AIIGCJOP_00466 2.2e-96 S protein conserved in bacteria
AIIGCJOP_00467 1.1e-105 IQ Short-chain dehydrogenase reductase Sdr
AIIGCJOP_00468 1.1e-70 yjgK G PFAM conserved
AIIGCJOP_00469 9e-220 3.2.1.51 GH29 G BNR repeat-like domain
AIIGCJOP_00470 5.7e-253 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AIIGCJOP_00471 1.5e-150 dapA_2 4.3.3.7 EM Belongs to the DapA family
AIIGCJOP_00472 9.7e-201 dhaT C alcohol dehydrogenase
AIIGCJOP_00473 1.2e-190 ygbK 2.7.1.219, 2.7.1.220 G type III effector
AIIGCJOP_00474 1.3e-179 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AIIGCJOP_00475 7.4e-130 K transcriptional regulator
AIIGCJOP_00476 4.8e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AIIGCJOP_00477 6.2e-74 ysnE K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AIIGCJOP_00478 8.7e-159 yneJ K Transcriptional regulator
AIIGCJOP_00479 2.3e-246 sad 1.2.1.16, 1.2.1.20, 1.2.1.24, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_00480 7.8e-251 cheD_2 NT Chemotaxis
AIIGCJOP_00481 1.4e-162 glsA 3.5.1.2 E Belongs to the glutaminase family
AIIGCJOP_00482 1.3e-223 yneF T Diguanylate cyclase
AIIGCJOP_00483 2.2e-156 yaiC 2.7.7.65 T Diguanylate cyclase
AIIGCJOP_00484 1.4e-157 T Diguanylate cyclase
AIIGCJOP_00485 4.2e-275 uxaB 1.1.1.11, 1.1.1.17, 1.1.1.57, 1.1.1.58 G Belongs to the mannitol dehydrogenase family. UxaB subfamily
AIIGCJOP_00486 2e-161 yneE S Membrane
AIIGCJOP_00487 7.5e-183 S Alpha beta hydrolase
AIIGCJOP_00488 1.7e-131 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_00489 2.9e-219 cpxA 2.7.13.3 T phosphorelay sensor kinase activity and signal transduction
AIIGCJOP_00490 3e-16 cpxA 2.7.13.3 T phosphorelay sensor kinase activity and signal transduction
AIIGCJOP_00491 1.2e-200 dipZ CO cytochrome c biogenesis protein
AIIGCJOP_00492 1.7e-134 tam 2.1.1.144, 2.1.1.197 S Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate
AIIGCJOP_00493 2.4e-96 nudK 3.6.1.13 L Nudix-type nucleoside diphosphatase, YffH AdpP family
AIIGCJOP_00494 6.4e-118 glcR 3.6.4.12 K transcriptional regulator
AIIGCJOP_00495 3.7e-49
AIIGCJOP_00496 2.1e-43 bigR K transcriptional regulator
AIIGCJOP_00497 1e-59 E transporter component
AIIGCJOP_00498 5e-56 S Transporter Component
AIIGCJOP_00499 1e-100 grxB O Glutaredoxin 2
AIIGCJOP_00500 4.1e-42 yebG S YebG family
AIIGCJOP_00502 1e-103 cat 2.3.1.28 V This enzyme is an effector of chloramphenicol resistance in bacteria
AIIGCJOP_00503 1.5e-151 T Diguanylate cyclase
AIIGCJOP_00504 9.7e-122 I Alpha/beta hydrolase family
AIIGCJOP_00505 1.3e-153 1.11.1.10 I Serine aminopeptidase, S33
AIIGCJOP_00506 1.6e-50 mgrA K transcription factor activity and regulation of transcription
AIIGCJOP_00507 3.1e-43 L 2OG-Fe(II) oxygenase superfamily
AIIGCJOP_00508 0.0 uvrA1 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AIIGCJOP_00509 4.8e-72 K transcriptional regulator
AIIGCJOP_00510 8.3e-22 ykkD P Multidrug Resistance protein
AIIGCJOP_00511 5.6e-26 ykkC P Multidrug Resistance protein
AIIGCJOP_00512 1.5e-153 nahR K transcriptional regulator
AIIGCJOP_00513 2.1e-186 EGP Major facilitator superfamily
AIIGCJOP_00514 1.2e-154 cpo 1.11.1.10 I Alpha beta hydrolase
AIIGCJOP_00515 1.6e-216 lysN EK Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AIIGCJOP_00516 0.0 P Receptor
AIIGCJOP_00517 6.6e-153 S amine dehydrogenase activity
AIIGCJOP_00518 1.6e-09 hipA 2.7.11.1 S protein related to capsule biosynthesis enzymes
AIIGCJOP_00519 8.9e-32 hipB K PFAM helix-turn-helix domain protein
AIIGCJOP_00520 0.0 tuaH 5.4.99.9 M COG0438 Glycosyltransferase
AIIGCJOP_00521 2.6e-160 L AAA domain
AIIGCJOP_00522 7.7e-202 yddW S Lipoprotein
AIIGCJOP_00523 6.7e-53 3.4.13.21 S ASCH
AIIGCJOP_00524 6.3e-42 IV02_09080 S conserved protein
AIIGCJOP_00525 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
AIIGCJOP_00526 0.0 treY 5.4.99.15 GH13 G synthase
AIIGCJOP_00527 1.4e-296 treZ 3.2.1.1, 3.2.1.141, 3.2.1.68 CBM48,GH13 G 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase
AIIGCJOP_00528 9e-167 tar NT methyl-accepting chemotaxis protein
AIIGCJOP_00529 3.8e-200 T EAL domain
AIIGCJOP_00530 2.1e-121 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
AIIGCJOP_00531 1.4e-148 K transcriptional regulator
AIIGCJOP_00532 3e-72 osmC O OsmC-like protein
AIIGCJOP_00533 1.1e-27 bdm S positive regulation of bacterial-type flagellum assembly
AIIGCJOP_00534 8.4e-16 sra J Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein
AIIGCJOP_00536 0.0 maeA 1.1.1.38 C Malic enzyme
AIIGCJOP_00537 4.4e-137 S Metallo-beta-lactamase superfamily
AIIGCJOP_00538 2.2e-99 K helix_turn_helix, arabinose operon control protein
AIIGCJOP_00539 2.5e-140 1.6.99.3 C Pyridine nucleotide-disulphide oxidoreductase
AIIGCJOP_00540 5.1e-107 IQ KR domain
AIIGCJOP_00541 7.2e-48 K helix_turn_helix, mercury resistance
AIIGCJOP_00542 6.6e-157 ynfM_2 EGP Major facilitator Superfamily
AIIGCJOP_00543 5.6e-295 tlrC S ABC transporter
AIIGCJOP_00544 6.9e-107 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AIIGCJOP_00545 6.2e-185 adhP 1.1.1.1 S alcohol dehydrogenase
AIIGCJOP_00546 3.2e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
AIIGCJOP_00547 1.1e-148 P Binding-protein-dependent transport system inner membrane component
AIIGCJOP_00548 6.8e-60 P Binding-protein-dependent transport system inner membrane component
AIIGCJOP_00549 9.3e-260 P Belongs to the ABC transporter superfamily
AIIGCJOP_00550 2.9e-158 MA20_00170 C Luciferase-like monooxygenase
AIIGCJOP_00551 2.3e-169 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AIIGCJOP_00552 2.1e-88 K Bacterial regulatory proteins, tetR family
AIIGCJOP_00553 5.7e-93 kefF 1.6.5.2 S NADPH-dependent FMN reductase
AIIGCJOP_00554 5.9e-187 araJ EGP Major facilitator Superfamily
AIIGCJOP_00555 1.9e-144 ppk2 2.7.4.1 H polyphosphate kinase
AIIGCJOP_00556 3.1e-116 fdnI C TIGRFAM Formate dehydrogenase, gamma subunit
AIIGCJOP_00557 7.4e-174 fdnH C formate dehydrogenase
AIIGCJOP_00558 0.0 fdnG 1.17.1.9, 1.17.5.3 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_00559 1.7e-105 fdnG 1.17.1.9, 1.17.5.3 C Molybdopterin oxidoreductase Fe4S4 domain
AIIGCJOP_00560 1.1e-148 yddG EG of the drug metabolite transporter (DMT) superfamily
AIIGCJOP_00561 9.4e-167 K Transcriptional regulator
AIIGCJOP_00562 1.1e-145 livH E Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_00563 8.6e-196 livM E Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_00564 6.7e-139 livG E Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids
AIIGCJOP_00565 2.8e-123 livF P Belongs to the ABC transporter superfamily
AIIGCJOP_00566 9.9e-211 livK E Extracellular ligand-binding receptor
AIIGCJOP_00567 1.2e-85 K L-2-amino-thiazoline-4-carboxylic acid hydrolase
AIIGCJOP_00568 2.1e-211 amaB 3.5.1.6, 3.5.1.87 E the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia
AIIGCJOP_00569 2.3e-137 P Binding-protein-dependent transport systems inner membrane component
AIIGCJOP_00570 2.2e-111 P Binding-protein-dependent transport systems inner membrane component
AIIGCJOP_00571 2.3e-191 S extracellular solute-binding protein, family 1
AIIGCJOP_00572 1.8e-149 3.6.3.30 P Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system
AIIGCJOP_00573 1.6e-113 MA20_22080 S of the beta-lactamase superfamily III
AIIGCJOP_00574 2.1e-151 K Bacterial regulatory proteins, lacI family
AIIGCJOP_00575 3.8e-223 smvA EGP Major facilitator superfamily
AIIGCJOP_00576 9.6e-90 ybjK K transcriptional regulator
AIIGCJOP_00577 5.3e-251 narU P nitrate nitrite transporter
AIIGCJOP_00578 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_00579 7.3e-310 narH 1.7.5.1 C nitrate reductase beta subunit
AIIGCJOP_00580 2.7e-118 narJ 1.7.5.1 C nitrate reductase molybdenum cofactor assembly chaperone
AIIGCJOP_00581 1.1e-124 narI 1.7.5.1 C nitrate reductase, gamma subunit
AIIGCJOP_00582 5.3e-37 chpR K Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to the MazF endoribonuclease toxin and neutralizes its endoribonuclease activity. Is considered to be an 'addiction' molecule as the cell dies in its absence. Toxicity results when the levels of MazE decrease in the cell, leading to mRNA degradation. This effect can be rescued by expression of MazE, but after 6 hours in rich medium the overexpression of MazF leads to programmed cell death. Cell growth and viability are not affected when MazF and MazE are coexpressed. Both MazE and MazE-MazF bind to the promoter region of the mazE- mazF operon to inhibit their own transcription. There are 3 operators to which MazE binds. MazE has higher affinity for promoter DNA in the presence of MazF
AIIGCJOP_00583 1.2e-52 chpA T Transcriptional modulator of MazE toxin, MazF
AIIGCJOP_00584 3.4e-152 nhoA 2.3.1.118, 2.3.1.5 Q Belongs to the arylamine N-acetyltransferase family
AIIGCJOP_00585 1.4e-266 ftpA P ABC-type Fe3 transport system permease component
AIIGCJOP_00586 2e-172 ftpB P ABC transporter substrate-binding protein
AIIGCJOP_00587 2.1e-115 phnT 3.6.3.30 E (ABC) transporter
AIIGCJOP_00588 9.8e-103 yddH S Flavin reductase
AIIGCJOP_00589 2.6e-101 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AIIGCJOP_00590 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AIIGCJOP_00591 3.3e-159 ttuD 2.7.1.165 G Hydroxypyruvate reductase
AIIGCJOP_00592 7.8e-178 ttuC 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
AIIGCJOP_00593 3.2e-189 G Major facilitator superfamily
AIIGCJOP_00594 1.1e-89 K LysR substrate binding domain
AIIGCJOP_00595 1.8e-34 pptA 5.3.2.6 S Belongs to the 4-oxalocrotonate tautomerase family
AIIGCJOP_00596 1.7e-116 yncG 2.5.1.18 O Glutathione S-Transferase
AIIGCJOP_00597 7.2e-153 fliY ET ABC transporter substrate-binding protein
AIIGCJOP_00598 4.4e-138 gluA 3.6.3.21 E (ABC) transporter
AIIGCJOP_00599 2.9e-157 P amino acid ABC transporter
AIIGCJOP_00600 1.6e-88 K N-acetyltransferase
AIIGCJOP_00601 8.3e-168 fliY_4 ET ABC transporter substrate-binding protein
AIIGCJOP_00602 2.8e-246 moxC C monooxygenase
AIIGCJOP_00603 9.3e-198 yxeP 3.5.1.32 S amidohydrolase
AIIGCJOP_00604 7.3e-162 ytmO C Luciferase Family
AIIGCJOP_00605 8.4e-88 adk 2.7.4.3 F adenylate kinase
AIIGCJOP_00606 2.8e-189 aer T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
AIIGCJOP_00607 5.2e-149 bacE EGP Major facilitator Superfamily
AIIGCJOP_00608 2e-153 T MASE1
AIIGCJOP_00609 1.7e-219 S response to pH
AIIGCJOP_00610 5.3e-71 S conserved protein, contains double-stranded beta-helix domain
AIIGCJOP_00611 1.6e-147 dmlR_3 K Transcriptional regulator
AIIGCJOP_00613 2.2e-271 ansP E Involved in the transporte of L-asparagine
AIIGCJOP_00614 3e-66 yjgH J endoribonuclease L-PSP
AIIGCJOP_00615 2.9e-89 K transcriptional regulator
AIIGCJOP_00616 7e-187 yncE S DNA binding
AIIGCJOP_00617 0.0 yncD P receptor
AIIGCJOP_00618 3.7e-112 tar NT helical bimodular (HBM) domain
AIIGCJOP_00619 8.6e-82 mcbR K FCD
AIIGCJOP_00620 2.1e-180 yncB S nadp-dependent
AIIGCJOP_00621 1.3e-97 K Helix-turn-helix domain
AIIGCJOP_00622 5.6e-89 yncA 2.3.1.183 M N-acetyltransferase
AIIGCJOP_00623 1.8e-67 ydcZ S membrane
AIIGCJOP_00624 2.1e-27 ydcY S Protein of unknown function (DUF2526)
AIIGCJOP_00625 6.6e-306 dppA E ABC-Type Dipeptide Transport System Periplasmic Component
AIIGCJOP_00626 6.1e-180 srfA S Virulence effector protein
AIIGCJOP_00627 0.0 srfB S PFAM virulence protein SrfB
AIIGCJOP_00628 0.0 srfC S Virulence
AIIGCJOP_00630 3.4e-22 ydcX S Toxin GhoT_OrtT
AIIGCJOP_00631 6.4e-49 yeaR P Domain of unknown function (DUF1971)
AIIGCJOP_00632 3.9e-57 P Domain of unknown function (DUF1971)
AIIGCJOP_00633 1.5e-25 yoaG S Domain of unknown function (DUF1869)
AIIGCJOP_00634 1.9e-227 N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AIIGCJOP_00635 2.3e-265 prr 1.2.1.19, 1.2.1.3 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_00636 3.4e-141 ydcV P ABC transporter (permease)
AIIGCJOP_00637 1.9e-167 ydcU P ABC transporter (Permease
AIIGCJOP_00638 5.3e-176 ydcT 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AIIGCJOP_00639 1.2e-221 ydcS E Spermidine putrescine ABC transporter substrate-binding protein
AIIGCJOP_00640 9.4e-264 ydcR 2.7.7.65 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AIIGCJOP_00641 1.9e-23
AIIGCJOP_00642 1.6e-191 luxA_2 C Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AIIGCJOP_00643 2.9e-27
AIIGCJOP_00644 6.7e-262 cioA 1.10.3.14 C oxidase, subunit
AIIGCJOP_00645 3.9e-179 cioB 1.10.3.14 C oxidase subunit
AIIGCJOP_00646 1.1e-12 S Protein of unknown function (DUF2474)
AIIGCJOP_00647 7.6e-30 yncJ S Protein of unknown function (DUF2554)
AIIGCJOP_00648 0.0 ydcP O peptidase U32
AIIGCJOP_00649 1e-93 ydcN K transcriptional regulator
AIIGCJOP_00650 3.2e-193 ydcO Q protein involved in benzoate metabolism
AIIGCJOP_00651 6.6e-159 K AraC family transcriptional regulator
AIIGCJOP_00652 2.6e-158 BP3797 EG of the drug metabolite transporter (DMT) superfamily
AIIGCJOP_00653 1.8e-119 ydcL S Protein of unknown function (DUF3313)
AIIGCJOP_00654 6.4e-301 dppA E ABC-Type Dipeptide Transport System Periplasmic Component
AIIGCJOP_00655 5e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AIIGCJOP_00656 2.2e-105 tehB 2.1.1.265 Q Tellurite resistance protein TehB
AIIGCJOP_00657 2e-175 tehA P PFAM C4-dicarboxylate transporter malic acid transport protein
AIIGCJOP_00658 8e-137 ydcK M Homologous to orf229 gp Streptococcus thermophilus bacteriophage Sfi19 gi 9632919 ref NP_049948.1
AIIGCJOP_00659 3e-93 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AIIGCJOP_00660 0.0 mdoD P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AIIGCJOP_00661 6.1e-140 ET belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_00662 5.1e-215 ybdL 2.6.1.17, 2.6.1.88 E aminotransferase
AIIGCJOP_00663 2.8e-146 K transcriptional regulator
AIIGCJOP_00664 1.5e-264 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
AIIGCJOP_00665 1.6e-249 ydcJ S protein conserved in bacteria
AIIGCJOP_00666 0.0 dmsA 1.8.5.3 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_00667 5.7e-120 C reductase chain B
AIIGCJOP_00668 2e-104 S anaerobic DMSO reductase chain C anchor subunit
AIIGCJOP_00669 4.9e-69 etfA 1.12.98.1, 1.18.1.2, 1.19.1.1 C 4Fe-4S dicluster domain
AIIGCJOP_00670 8.8e-162 pcaQ K transcriptional regulator
AIIGCJOP_00671 0.0 quiA 1.1.5.8 G Dehydrogenase
AIIGCJOP_00672 2e-58 M Gram-negative bacterial TonB protein C-terminal
AIIGCJOP_00673 4.5e-180 trg NT chemotaxis, protein
AIIGCJOP_00674 2.9e-215 frmA 1.1.1.1, 1.1.1.284 C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily
AIIGCJOP_00675 2.7e-42 frmR S protein conserved in bacteria
AIIGCJOP_00676 5.3e-17 ariR K Probably a connector protein for RcsB C regulation of biofilm and acid-resistance, providing additional signal input into the two-component signaling pathway. May serve to stimulate biofilm maturation, via the Rcs phosphorelay. Regulates expression of genes involved in acid-resistance and biofilm formation, including the RcsB C two-component system. May be a non-specific DNA-binding protein that binds genes and or intergenic regions via a geometric recognition. Also confers resistance to H(2)O(2). Overexpression at 28 and 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB
AIIGCJOP_00677 5.3e-07
AIIGCJOP_00678 3.2e-15 ycgZ S Biofilm development protein YmgB/AriR
AIIGCJOP_00679 1.7e-25
AIIGCJOP_00680 1.8e-131
AIIGCJOP_00681 3.4e-167 S Domain of unknown function (DUF1852)
AIIGCJOP_00682 3.1e-192 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AIIGCJOP_00683 5.4e-78 1.11.1.12, 1.11.1.9 O Belongs to the glutathione peroxidase family
AIIGCJOP_00685 8.3e-125 yedK S Belongs to the SOS response-associated peptidase family
AIIGCJOP_00686 5e-200 umuC 2.7.7.7 L DNA polymerase
AIIGCJOP_00687 3.9e-131 dsbG 5.3.4.1 O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AIIGCJOP_00688 0.0 dsbD 1.8.1.8 CO Disulphide bond corrector protein DsbC
AIIGCJOP_00689 4.8e-14 VPA1614
AIIGCJOP_00690 2.3e-67 pgaD S Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD
AIIGCJOP_00691 7.3e-250 pgaC GT2 M Poly-beta-1,6-N-acetyl-D-glucosamine synthase
AIIGCJOP_00692 0.0 pgaB G Polysaccharide deacetylase
AIIGCJOP_00693 0.0 H Exports the biofilm adhesin polysaccharide poly-beta- 1,6-N-acetyl-D-glucosamine (PGA) across the outer membrane. The PGA transported seems to be partially N-deacetylated since N- deacetylation of PGA by PgaB is needed for PGA export through the PgaA porin
AIIGCJOP_00694 1.9e-264 S Protein of unknown function (DUF560)
AIIGCJOP_00695 3.2e-08 mrcB 2.4.1.129, 3.4.16.4 GT51 M Pfam:Lipoprotein_5
AIIGCJOP_00696 2.4e-21 V HNH endonuclease
AIIGCJOP_00697 2.5e-83 S polyketide cyclase
AIIGCJOP_00698 9.1e-114 M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AIIGCJOP_00699 8.1e-97 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_00700 4.2e-111 K AraC family transcriptional regulator
AIIGCJOP_00701 4.7e-122 K transcriptional
AIIGCJOP_00702 1.8e-130 GM Nad-dependent epimerase dehydratase
AIIGCJOP_00703 2e-126 GM NmrA-like family
AIIGCJOP_00704 1.6e-112 S Beta-lactamase
AIIGCJOP_00705 4.2e-135 mexT K transcriptional regulator
AIIGCJOP_00706 7.2e-121 K AraC-type transcriptional regulator N-terminus
AIIGCJOP_00707 6.2e-121 IQ short-chain dehydrogenase
AIIGCJOP_00708 3.2e-41 yjgJ K tetR family
AIIGCJOP_00709 1e-113 S Protein of unknown function (DUF1214)
AIIGCJOP_00710 1.2e-45 M Glycosyltransferase sugar-binding region containing DXD motif
AIIGCJOP_00711 1.1e-66 umuD KT Belongs to the peptidase S24 family
AIIGCJOP_00712 1.4e-173 yhdH C Quinone oxidoreductase, YhdH YhfP family
AIIGCJOP_00713 7.1e-113 nemR K Bacterial transcriptional repressor C-terminal
AIIGCJOP_00714 5.2e-122 yjiJ EGP Major facilitator Superfamily
AIIGCJOP_00716 6e-99 gltR_2 K LysR substrate binding domain
AIIGCJOP_00717 2.5e-128 yrpB 1.13.12.16 S Nitronate monooxygenase
AIIGCJOP_00718 8.6e-125 K Transcriptional regulator
AIIGCJOP_00719 3.1e-98 IQ reductase
AIIGCJOP_00720 6e-20 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
AIIGCJOP_00722 9.3e-127 GM NmrA-like family
AIIGCJOP_00723 2.5e-124 K Transcriptional regulator
AIIGCJOP_00724 7.7e-96 S Phosphohydrolase
AIIGCJOP_00725 1.3e-99 K transcriptional regulator
AIIGCJOP_00726 1.8e-54 S Putative stress-induced transcription regulator
AIIGCJOP_00727 6.9e-140 S Alpha/beta hydrolase family
AIIGCJOP_00728 7.7e-254 mscM M mechanosensitive ion channel
AIIGCJOP_00729 3.1e-132 dapA5 4.3.3.7 EM Belongs to the DapA family
AIIGCJOP_00732 1.1e-178 EGP Sugar (and other) transporter
AIIGCJOP_00733 1.7e-93 cybB C B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm
AIIGCJOP_00734 2.1e-180 gap 1.2.1.12, 1.2.1.72 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AIIGCJOP_00735 2.1e-163 xynB I esterase lipase
AIIGCJOP_00736 2.5e-264 aldA 1.2.1.21, 1.2.1.22 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_00737 3.5e-138 ydcF S DUF218 domain
AIIGCJOP_00738 6.4e-238 proP EGP Major facilitator superfamily
AIIGCJOP_00739 9.3e-271 rmrB EGP Major facilitator superfamily
AIIGCJOP_00740 5.7e-144 hlyD V HlyD membrane-fusion protein of T1SS
AIIGCJOP_00741 5.1e-230 oprM M membrane
AIIGCJOP_00742 2e-115 mdmC 2.1.1.104 S O-Methyltransferase
AIIGCJOP_00743 0.0 hrpA 3.6.4.13 L ATP-dependent helicase hrpA
AIIGCJOP_00744 3.2e-104 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AIIGCJOP_00745 2.4e-194 G Major facilitator superfamily
AIIGCJOP_00746 1.3e-83 K Transcriptional regulator
AIIGCJOP_00747 4.3e-63 ttr K Acetyltransferase (GNAT) domain
AIIGCJOP_00748 1.9e-55 2.7.11.1 T Anti-sigma regulatory factor (Ser Thr protein kinase)
AIIGCJOP_00749 8.8e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
AIIGCJOP_00750 5.1e-202 3.1.3.3 T response regulator
AIIGCJOP_00751 6.8e-167
AIIGCJOP_00752 1.3e-216 S OpgC protein
AIIGCJOP_00753 0.0 2.4.1.12 GT2 M Cellulose synthase
AIIGCJOP_00754 3.9e-227 NU Protein of unknown function (DUF3131)
AIIGCJOP_00755 5.6e-278 G Protein of unknown function (DUF3131)
AIIGCJOP_00756 5.3e-251 G Protein of unknown function (DUF3131)
AIIGCJOP_00757 3.2e-69 VPA1107 C nitric oxide dioxygenase activity
AIIGCJOP_00758 0.0 T PhoQ Sensor
AIIGCJOP_00759 0.0 3.2.1.25 G Belongs to the glycosyl hydrolase 2 family
AIIGCJOP_00760 3.5e-37 S RelE toxin of RelE / RelB toxin-antitoxin system
AIIGCJOP_00761 5.7e-85 paaY S Phenylacetic acid degradation protein PaaY
AIIGCJOP_00762 1.8e-170 paaX K phenylacetic acid degradation operon negative regulatory protein
AIIGCJOP_00763 1.6e-247 paaK 6.2.1.30 H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AIIGCJOP_00764 5.3e-215 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
AIIGCJOP_00765 2.1e-73 paaI Q phenylacetic acid degradation protein
AIIGCJOP_00766 1.7e-233 paaH 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I 3-hydroxyacyl-coa dehydrogenase
AIIGCJOP_00767 2.5e-141 paaG 5.3.3.18 I Enoyl-CoA hydratase
AIIGCJOP_00768 3.3e-122 paaF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
AIIGCJOP_00769 2.3e-193 paaE C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
AIIGCJOP_00770 2.3e-87 paaD L phenylacetate-CoA oxygenase, PaaJ subunit
AIIGCJOP_00771 2.2e-131 paaC 1.14.13.149 S Phenylacetate-CoA oxygenase, PaaI subunit
AIIGCJOP_00772 3.1e-49 paaB Q Phenylacetate-CoA oxygenase
AIIGCJOP_00773 8e-179 paaA 1.14.13.149 S Phenylacetate-CoA oxygenase
AIIGCJOP_00774 0.0 paaN 1.2.1.91, 3.3.2.12 CI Aldehyde dehydrogenase
AIIGCJOP_00775 0.0 tynA 1.4.3.21 Q amine oxidase
AIIGCJOP_00776 0.0 yjcS Q COG2015 Alkyl sulfatase and related hydrolases
AIIGCJOP_00777 2.8e-114 2.7.7.65 T diguanylate cyclase
AIIGCJOP_00778 2.7e-285 feaB 1.2.1.39 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_00779 2.1e-163 feaR K transcriptional regulator
AIIGCJOP_00780 1.3e-43 ydbL S protein conserved in bacteria
AIIGCJOP_00781 1.6e-25 ynbE S (Lipo)protein
AIIGCJOP_00782 0.0 ydbH S Dicarboxylate transport
AIIGCJOP_00783 7.7e-180 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AIIGCJOP_00784 6.1e-62 hslJ O Heat shock protein
AIIGCJOP_00785 4.2e-40 ydbJ S Domain of unknown function (DUF333)
AIIGCJOP_00786 0.0 nifJ 1.2.7.1 C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AIIGCJOP_00787 2.1e-189 ompN M PFAM porin Gram-negative type
AIIGCJOP_00788 3.3e-71 S Glutathione-dependent formaldehyde-activating
AIIGCJOP_00789 7.7e-75
AIIGCJOP_00790 2.9e-176 ttcA 6.3.4.19 J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system
AIIGCJOP_00791 1.1e-248 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
AIIGCJOP_00794 1.8e-181 zntB P Zinc transport protein zntB
AIIGCJOP_00795 1.3e-130 tse3 NT methyl-accepting chemotaxis protein
AIIGCJOP_00797 2.6e-217 ydaM 2.7.7.65 T Diguanylate cyclase
AIIGCJOP_00798 2.3e-99 pfpI 3.5.1.124 S Intracellular protease
AIIGCJOP_00799 2.4e-57
AIIGCJOP_00800 2.4e-128 M ImpA domain protein
AIIGCJOP_00801 3.7e-76 S Gene 25-like lysozyme
AIIGCJOP_00802 3.6e-86 tssJ S Type VI secretion
AIIGCJOP_00803 3.1e-198 S Type VI secretion, TssG
AIIGCJOP_00804 0.0 tssF S Type VI secretion
AIIGCJOP_00805 1.6e-09 S Protein of unknown function (DUF1240)
AIIGCJOP_00806 3.8e-45 S to Yersinia kristensenii ATCC 33638
AIIGCJOP_00807 6e-85 S to Yersinia kristensenii ATCC 33638
AIIGCJOP_00808 5.6e-25 S Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ
AIIGCJOP_00809 1.3e-101 kefF C Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC
AIIGCJOP_00810 0.0 kefC P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AIIGCJOP_00811 4.4e-88 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AIIGCJOP_00812 2.5e-163 apaH 3.6.1.41 T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AIIGCJOP_00813 1.7e-63 P mitochondrion morphogenesis
AIIGCJOP_00814 2.6e-149 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AIIGCJOP_00815 9.7e-183 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AIIGCJOP_00816 2e-228 surA 5.2.1.8 M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AIIGCJOP_00817 0.0 lptD M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AIIGCJOP_00818 7.6e-133 djlA O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host
AIIGCJOP_00819 5.8e-123 rluA 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AIIGCJOP_00820 0.0 rapA K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AIIGCJOP_00821 0.0 polB 2.7.7.7 L DNA polymerase
AIIGCJOP_00822 2.5e-132 araD 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 G Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate
AIIGCJOP_00823 1.9e-08 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
AIIGCJOP_00824 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
AIIGCJOP_00825 6.6e-164 araC K regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose
AIIGCJOP_00826 1.5e-135 yabI 3.6.1.27 I membrane-associated protein
AIIGCJOP_00827 5.5e-116 thiQ P Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AIIGCJOP_00828 2e-286 thiP P with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell
AIIGCJOP_00829 3.8e-179 tbpA P thiamine ABC transporter
AIIGCJOP_00830 0.0 sgrR K Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain
AIIGCJOP_00831 2.4e-16 S Inhibitor of glucose uptake transporter SgrT
AIIGCJOP_00832 3.7e-197 setA EGP Major facilitator Superfamily
AIIGCJOP_00833 8.8e-110 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AIIGCJOP_00834 2.4e-259 leuC 4.2.1.33, 4.2.1.35 H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AIIGCJOP_00835 9.3e-203 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AIIGCJOP_00836 5.9e-283 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AIIGCJOP_00837 4.9e-163 leuO K transcriptional regulator
AIIGCJOP_00838 0.0 ilvI 2.2.1.6 H acetolactate synthase
AIIGCJOP_00839 3.1e-81 ilvH 2.2.1.6 E acetolactate synthase
AIIGCJOP_00840 3e-187 fruR 3.2.1.26 GH32 K Transcriptional
AIIGCJOP_00841 7.2e-80 mraZ K Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster
AIIGCJOP_00842 1.2e-169 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AIIGCJOP_00843 3.3e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AIIGCJOP_00844 0.0 ftsI 3.4.16.4 M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum
AIIGCJOP_00845 1.9e-275 murE 3.4.16.4, 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AIIGCJOP_00846 1.5e-237 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AIIGCJOP_00847 8.7e-201 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AIIGCJOP_00848 5.7e-247 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AIIGCJOP_00849 3.1e-226 ftsW 2.4.1.227 GT28 M Peptidoglycan polymerase that is essential for cell division
AIIGCJOP_00850 6.3e-196 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AIIGCJOP_00851 8.6e-276 murC 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AIIGCJOP_00852 1.9e-164 ddl 1.3.1.98, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AIIGCJOP_00853 5.4e-150 ftsQ 6.3.2.4 D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AIIGCJOP_00854 3.7e-235 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AIIGCJOP_00855 3e-207 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AIIGCJOP_00856 7.2e-172 lpxC 3.5.1.108, 4.2.1.59 M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
AIIGCJOP_00857 8.6e-74 secM U Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation
AIIGCJOP_00858 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AIIGCJOP_00859 7.2e-65 mutT 3.6.1.55, 3.6.1.65 L belongs to the nudix hydrolase family
AIIGCJOP_00860 1.1e-29 yacG 2.7.1.24 S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AIIGCJOP_00861 1.7e-134 zapD D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AIIGCJOP_00862 3.3e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AIIGCJOP_00863 1.7e-193 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AIIGCJOP_00864 3.2e-172 hofC U type II secretion system
AIIGCJOP_00865 5.4e-240 hofB NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AIIGCJOP_00866 4.3e-69 ppdD NU Belongs to the N-Me-Phe pilin family
AIIGCJOP_00867 6.3e-157 nadC 2.4.2.19 H Belongs to the NadC ModD family
AIIGCJOP_00868 2e-103 ampD 3.5.1.28 V Negative regulator of beta-lactamase expression
AIIGCJOP_00869 2.9e-151 ampE 6.3.1.10 V regulatory protein AmpE
AIIGCJOP_00870 2.3e-189 abf G Belongs to the glycosyl hydrolase 43 family
AIIGCJOP_00871 3.6e-260 yicJ G COG2211 Na melibiose symporter and related transporters
AIIGCJOP_00872 1.5e-250 aroP E amino acid
AIIGCJOP_00873 1.6e-132 pdhR K Regulatory protein GntR HTH
AIIGCJOP_00874 0.0 aceE 1.2.4.1 C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AIIGCJOP_00875 1.7e-284 aceF 2.3.1.12 C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AIIGCJOP_00876 6.3e-268 lpdA 1.8.1.4 F Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes
AIIGCJOP_00877 2e-125 flgK N Protein of unknown function (DUF2950)
AIIGCJOP_00878 2.8e-160 yacH M Protein of unknown function (DUF3300)
AIIGCJOP_00880 0.0 acnB 4.2.1.3, 4.2.1.99 C Belongs to the aconitase IPM isomerase family
AIIGCJOP_00881 2.6e-61 yacL S Belongs to the UPF0231 family
AIIGCJOP_00882 4.1e-147 speD 2.5.1.16, 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AIIGCJOP_00883 1.5e-163 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AIIGCJOP_00884 7.3e-52 yacC S Type II secretion system pilotin lipoprotein (PulS_OutS)
AIIGCJOP_00885 7.8e-275 cueO Q Multi-copper
AIIGCJOP_00886 0.0 gcd 1.1.5.2 C Dehydrogenase
AIIGCJOP_00887 1.5e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AIIGCJOP_00888 9.9e-123 can 4.2.1.1 P Reversible hydration of carbon dioxide
AIIGCJOP_00889 1.4e-162 yadG V AAA domain, putative AbiEii toxin, Type IV TA system
AIIGCJOP_00890 1.5e-135 yadH V Transport Permease Protein
AIIGCJOP_00891 8.2e-73 yadI G IIa component
AIIGCJOP_00892 2.5e-220 yadE 3.5.1.41 G Polysaccharide deacetylase
AIIGCJOP_00893 7.1e-65 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AIIGCJOP_00894 3.2e-142 panC 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AIIGCJOP_00895 3.7e-140 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
AIIGCJOP_00896 3e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AIIGCJOP_00897 1.3e-249 pcnB 2.7.7.19, 2.7.7.72 H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control
AIIGCJOP_00898 8.8e-167 gluQ J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
AIIGCJOP_00899 1.6e-79 dksA K Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression
AIIGCJOP_00900 1.7e-117 sfsA S Belongs to the SfsA family
AIIGCJOP_00901 3.3e-92 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AIIGCJOP_00902 0.0 hrpB 3.6.4.13 L ATP-dependent helicase
AIIGCJOP_00903 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
AIIGCJOP_00904 0.0 fhuA P TonB-dependent siderophore receptor
AIIGCJOP_00905 6.3e-148 fhuC 3.6.3.34 HP ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
AIIGCJOP_00906 3e-159 fhuD P ABC-type Fe3 -hydroxamate transport system, periplasmic component
AIIGCJOP_00907 0.0 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AIIGCJOP_00908 2.8e-238 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
AIIGCJOP_00909 9.5e-245 clcA P Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response
AIIGCJOP_00910 2e-58 erpA C iron--sulfur cluster insertion protein erpA
AIIGCJOP_00911 7.7e-109 yadS S membrane
AIIGCJOP_00912 1e-118 btuF P Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC
AIIGCJOP_00913 6.8e-122 mtnN 3.2.2.9 F Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AIIGCJOP_00914 3.1e-281 dgt 3.1.5.1 F dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs
AIIGCJOP_00915 9.9e-237 degP 1.3.1.74, 3.4.21.107 M Belongs to the peptidase S1C family
AIIGCJOP_00916 5.1e-215 cdaR KT regulator
AIIGCJOP_00917 7.7e-67 yaeH S Belongs to the UPF0325 family
AIIGCJOP_00918 9.4e-123 dapD 2.3.1.117, 2.3.1.89 E Belongs to the transferase hexapeptide repeat family
AIIGCJOP_00919 0.0 glnD 2.7.7.59 O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AIIGCJOP_00920 1.6e-148 map 3.4.11.18 E Methionine aminopeptidase
AIIGCJOP_00921 4.4e-132 rpsB J ribosomal protein
AIIGCJOP_00922 1.3e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AIIGCJOP_00923 5.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AIIGCJOP_00924 1.2e-76 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AIIGCJOP_00925 2.9e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
AIIGCJOP_00926 7.3e-138 uppS 2.5.1.31 H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide
AIIGCJOP_00927 2.2e-159 cdsA 2.7.7.41 S Belongs to the CDS family
AIIGCJOP_00928 1.2e-247 rseP 3.4.21.107 M zinc metalloprotease
AIIGCJOP_00929 0.0 bamA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AIIGCJOP_00930 8.3e-74 skp M Belongs to the skp family
AIIGCJOP_00931 1.6e-111 lpxD 2.3.1.191 M as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AIIGCJOP_00932 4.9e-81 fabZ 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AIIGCJOP_00933 3e-94
AIIGCJOP_00934 3.3e-214 lpxB 2.4.1.182 GT19 M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AIIGCJOP_00935 1.9e-104 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AIIGCJOP_00936 0.0 dnaE 2.7.7.7 L DNA polymerase
AIIGCJOP_00937 1e-176 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AIIGCJOP_00938 0.0 ldcC 4.1.1.17, 4.1.1.18, 4.1.1.19 E decarboxylase
AIIGCJOP_00939 4.4e-70 yaeR E glyoxalase bleomycin resistance protein dioxygenase
AIIGCJOP_00940 1.2e-217 tilS 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AIIGCJOP_00941 4.1e-40 rof K Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination
AIIGCJOP_00942 3.6e-28 yaeP S Belongs to the UPF0253 family
AIIGCJOP_00943 1.9e-95 yaeQ S protein conserved in bacteria
AIIGCJOP_00944 4.2e-42 yaeJ J chain release factor
AIIGCJOP_00945 6.8e-114 cutF MP Copper homeostasis
AIIGCJOP_00946 5.2e-105 yaeF M cysteine-type peptidase activity
AIIGCJOP_00947 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AIIGCJOP_00948 5.6e-124 yaeB P PFAM Uncharacterised protein family UPF0066
AIIGCJOP_00949 5.8e-65 rcsF M colanic acid biosynthetic process
AIIGCJOP_00950 4.6e-146 metQ P Belongs to the NlpA lipoprotein family
AIIGCJOP_00951 3.6e-77 metI P ABC-type metal ion transport system permease component
AIIGCJOP_00952 1.2e-180 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AIIGCJOP_00953 5.2e-104 gmhB 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 6.3.2.10 E D,D-heptose 1,7-bisphosphate phosphatase
AIIGCJOP_00955 9.7e-30 yecF S Protein of unknown function (DUF2594)
AIIGCJOP_00956 1.4e-117 sdiA K Transcriptional regulator
AIIGCJOP_00957 2.5e-130 yecC 3.6.3.21 E (ABC) transporter
AIIGCJOP_00958 4.7e-112 yecS P amino acid ABC transporter
AIIGCJOP_00959 2.1e-177 dcyD 4.4.1.15 E Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine
AIIGCJOP_00960 1.3e-134 fliY ET belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_00961 1.1e-95 fliZ N biosynthesis protein FliZ
AIIGCJOP_00962 2.7e-126 fliA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes
AIIGCJOP_00963 2.1e-124 flaA N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AIIGCJOP_00964 1.3e-180 fliD N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AIIGCJOP_00965 1e-61 fliS N flagellar protein FliS
AIIGCJOP_00966 1.3e-44 fliT N Flagellar protein FliT
AIIGCJOP_00967 3.1e-289 amyA 3.2.1.1 GH13 G Cytoplasmic alpha-amylase
AIIGCJOP_00968 3.7e-67 yedD S (Lipo)protein
AIIGCJOP_00969 2.6e-44 fliE N Flagellar hook-basal body complex protein FliE
AIIGCJOP_00970 5.9e-273 fliF N The M ring may be actively involved in energy transduction
AIIGCJOP_00971 3.2e-173 fliG N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AIIGCJOP_00972 3.2e-79 fliH N Flagellar assembly protein
AIIGCJOP_00973 2.1e-252 fliI 3.6.3.14 NU Type III
AIIGCJOP_00974 2.3e-67 fliJ N Flagellar protein that affects chemotactic events
AIIGCJOP_00975 3.7e-144 fliK N Flagellar hook-length control protein
AIIGCJOP_00976 7.8e-74 fliL N Controls the rotational direction of flagella during chemotaxis
AIIGCJOP_00977 2.3e-187 fliM N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AIIGCJOP_00978 8.2e-67 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AIIGCJOP_00979 1.5e-51 fliO N flagellar
AIIGCJOP_00980 4.6e-121 fliP N Plays a role in the flagellum-specific transport system
AIIGCJOP_00981 2.9e-36 fliQ N Flagellar biosynthetic protein FliQ
AIIGCJOP_00982 9.3e-112 fliR N Role in flagellar biosynthesis
AIIGCJOP_00983 4.6e-106 rcsA K Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes
AIIGCJOP_00984 1.7e-27 dsrB S Dextransucrase DSRB
AIIGCJOP_00985 1.6e-32 yodD S single-species biofilm formation on inanimate substrate
AIIGCJOP_00986 6.9e-134 yedP 2.7.1.31, 3.1.3.70 S Mannosyl-3-phosphoglycerate phosphatase
AIIGCJOP_00987 2.3e-229 yedQ 2.7.7.65 T Protein involved in phosphorus-oxygen lyase activity, regulation of signal transduction, cyclic nucleotide biosynthetic process and intracellular signal transduction
AIIGCJOP_00988 3.1e-26 yodC S Uncharacterized small protein (DUF2158)
AIIGCJOP_00989 5.4e-127 yedI S protein conserved in bacteria
AIIGCJOP_00990 7.7e-150 yedA EG of the drug metabolite transporter (DMT) superfamily
AIIGCJOP_00991 2e-80 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
AIIGCJOP_00992 7.2e-264 dcm 2.1.1.37 H Methyl-transferase
AIIGCJOP_00993 1.9e-108 yedJ S Metal-dependent phosphohydrolase
AIIGCJOP_00994 1.4e-30 yedR
AIIGCJOP_00995 2.6e-181 M Gram-negative porin
AIIGCJOP_00996 3.3e-273 dcuS 2.7.13.3 T signal transduction histidine kinase regulating citrate malate metabolism
AIIGCJOP_00997 6.4e-123 dcuR K Transcriptional Regulatory protein
AIIGCJOP_00999 5.3e-147 mtfA C Belongs to the MtfA family
AIIGCJOP_01001 2.3e-10 L Belongs to the 'phage' integrase family
AIIGCJOP_01002 2.3e-12 L Belongs to the 'phage' integrase family
AIIGCJOP_01003 1.5e-46 proV 3.6.3.32 K Helix-turn-helix domain
AIIGCJOP_01004 2.1e-55 S Phage derived protein Gp49-like (DUF891)
AIIGCJOP_01005 1.5e-24 nlp K transcriptional regulator
AIIGCJOP_01006 2.5e-56
AIIGCJOP_01007 1.1e-104 T Nacht domain
AIIGCJOP_01008 1.5e-105 T Nacht domain
AIIGCJOP_01009 0.0
AIIGCJOP_01010 0.0
AIIGCJOP_01011 6.1e-155
AIIGCJOP_01012 8.8e-173 cbl K transcriptional regulator
AIIGCJOP_01013 8e-155 nac K transcriptional regulator
AIIGCJOP_01015 1.8e-157 erfK S Catalyzes th removal of D-alanine and attachment of the murein lipoprotein to the peptidoglycan tetrapeptide chain
AIIGCJOP_01016 5.7e-231 shiA EGP Major facilitator superfamily
AIIGCJOP_01017 8.4e-284 amn 3.2.2.4 F Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations
AIIGCJOP_01018 0.0 pepP 3.4.11.9 E xaa-pro aminopeptidase
AIIGCJOP_01020 6e-258 yeeO V Mate efflux family protein
AIIGCJOP_01022 6.7e-51 yeeX S Belongs to the UPF0265 family
AIIGCJOP_01023 1e-190 yeeA S Membrane
AIIGCJOP_01024 2.7e-82 sbmC L Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AIIGCJOP_01025 1.2e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AIIGCJOP_01026 1.8e-270 sbcB 3.1.11.1 L Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
AIIGCJOP_01027 2.2e-249 yeeF E PFAM amino acid permease-associated region
AIIGCJOP_01028 2e-161 yeeY K transcriptional regulator
AIIGCJOP_01029 9.7e-152 yeeZ GM COG0451 Nucleoside-diphosphate-sugar epimerases
AIIGCJOP_01030 1e-162 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AIIGCJOP_01031 6.7e-224 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AIIGCJOP_01032 2e-189 hisC 1.1.1.23, 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AIIGCJOP_01033 2.9e-201 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19 E Histidine biosynthesis bifunctional protein HisB
AIIGCJOP_01034 1e-107 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AIIGCJOP_01035 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AIIGCJOP_01036 2e-143 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AIIGCJOP_01037 3.4e-109 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AIIGCJOP_01038 2.3e-144 wzzB M chain length
AIIGCJOP_01039 2.1e-188 capI 5.1.3.6 M epimerase dehydratase
AIIGCJOP_01040 2.5e-206 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AIIGCJOP_01041 5e-265 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AIIGCJOP_01042 6e-135 galE 5.1.3.2 M Polysaccharide biosynthesis protein
AIIGCJOP_01043 5e-143 2.4.1.52 GT4 M to RfpB of Escherichia coli UniRef RepID B3I2Q7_ECOLX
AIIGCJOP_01044 6.9e-97 wbpT GT4 M Glycosyl transferase 4-like
AIIGCJOP_01045 1.1e-46 cpsO M Glycosyltransferase like family 2
AIIGCJOP_01046 3.5e-46 rgpB GT2 M Glycosyl transferase family 2
AIIGCJOP_01047 1.1e-18
AIIGCJOP_01048 1.9e-111 rfbE S Polysaccharide biosynthesis protein
AIIGCJOP_01049 5e-154 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AIIGCJOP_01050 5.2e-151 rfbD 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AIIGCJOP_01051 3.4e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AIIGCJOP_01052 2.1e-160 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AIIGCJOP_01053 2.1e-244 wcaM S Colanic acid biosynthesis protein
AIIGCJOP_01054 6.3e-224 wcaL GT4 M Glycosyl Transferase
AIIGCJOP_01055 1.3e-240 wcaK S biosynthesis protein
AIIGCJOP_01056 6.4e-255 wzxC S Membrane protein involved in the export of O-antigen and teichoic acid
AIIGCJOP_01057 6.4e-265 wcaJ M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
AIIGCJOP_01058 4.1e-264 manB 5.4.2.2, 5.4.2.8 G phosphomannomutase
AIIGCJOP_01059 1.9e-264 cpsB 2.7.7.13, 5.3.1.8 GM Belongs to the mannose-6-phosphate isomerase type 2 family
AIIGCJOP_01060 1.4e-215 wcaI GT4 M glycosyl transferase group 1
AIIGCJOP_01061 2.1e-82 gmm 3.6.1.55 F Belongs to the Nudix hydrolase family
AIIGCJOP_01062 4.1e-178 fcl 1.1.1.271, 4.2.1.47 GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
AIIGCJOP_01063 1.3e-210 gmd 4.2.1.47 M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AIIGCJOP_01064 5.7e-100 wcaF 2.3.1.79 S colanic acid biosynthesis acetyltransferase wcaF
AIIGCJOP_01065 6.5e-131 wcaE GT2 M Pfam Glycosyl transferase family 2
AIIGCJOP_01066 2e-214 wcaD S colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance
AIIGCJOP_01067 2.3e-226 wcaC GT4 M Glycosyl Transferase
AIIGCJOP_01068 1.4e-76 wcaB 2.3.1.30 E Belongs to the transferase hexapeptide repeat family
AIIGCJOP_01069 2.7e-152 wcaA M PFAM Glycosyl transferase, family 2
AIIGCJOP_01070 0.0 wzc D protein involved in exopolysaccharide biosynthesis
AIIGCJOP_01071 2.5e-77 wzb 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AIIGCJOP_01072 1.5e-208 wza M polysaccharide export
AIIGCJOP_01073 3.5e-283 yegH P membrane protein, terc
AIIGCJOP_01074 5.1e-311 asmA M Protein involved in outer membrane biogenesis
AIIGCJOP_01075 1.9e-106 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
AIIGCJOP_01076 4.3e-115 udk 2.7.1.48 F Cytidine monophosphokinase
AIIGCJOP_01077 0.0 yegE 2.1.1.80, 2.7.13.3, 2.7.7.65, 3.1.1.61 T MASE1 domain protein
AIIGCJOP_01078 2.9e-154 alkA 3.2.2.21 L 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AIIGCJOP_01079 6.7e-251 yegD O Belongs to the heat shock protein 70 family
AIIGCJOP_01080 2.9e-192 mdtA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AIIGCJOP_01081 0.0 mdtB V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AIIGCJOP_01082 0.0 mdtC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AIIGCJOP_01083 1.2e-245 mdtD EGP Major facilitator superfamily
AIIGCJOP_01084 1.2e-263 T PhoQ Sensor
AIIGCJOP_01085 3.4e-132 K response regulator
AIIGCJOP_01086 1.7e-123 ycgE K Transcriptional regulator
AIIGCJOP_01087 3.1e-207 ycgF T EAL domain
AIIGCJOP_01088 3.8e-32 ycgZ S Two-component-system connector protein YcgZ
AIIGCJOP_01089 5.2e-37
AIIGCJOP_01090 2.7e-31 ariR S Two-component-system connector protein AriR
AIIGCJOP_01091 1.1e-258 yegQ O protease
AIIGCJOP_01092 8.1e-152 yegS 2.7.1.107 I the in vivo substrate is
AIIGCJOP_01093 1.4e-136 EP (ABC) transporter
AIIGCJOP_01094 4.9e-154 oppD EP (ABC) transporter
AIIGCJOP_01095 2.4e-156 P Binding-protein-dependent transport systems inner membrane component
AIIGCJOP_01096 4.6e-183 dppB_1 P PFAM binding-protein-dependent transport systems inner membrane component
AIIGCJOP_01097 6e-307 E Extracellular solute-binding protein, family 5
AIIGCJOP_01098 3.1e-228 M Belongs to the mandelate racemase muconate lactonizing enzyme family
AIIGCJOP_01099 8.7e-198 fbaB 4.1.2.13 G Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate
AIIGCJOP_01100 2e-138 thiD 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
AIIGCJOP_01101 2.4e-128 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AIIGCJOP_01105 4.1e-125 L Reverse transcriptase (RNA-dependent DNA polymerase)
AIIGCJOP_01106 6.3e-65 L Resolvase, N terminal domain
AIIGCJOP_01107 2.1e-31
AIIGCJOP_01108 1.6e-13
AIIGCJOP_01109 1.1e-14
AIIGCJOP_01110 1.7e-46
AIIGCJOP_01111 7.6e-264 NU Usher protein
AIIGCJOP_01112 4.4e-96 NU Fimbrial protein
AIIGCJOP_01113 4.4e-36 NU Fimbrial protein
AIIGCJOP_01114 8e-54 K LuxR family transcriptional regulator
AIIGCJOP_01115 1.7e-45 K response regulator
AIIGCJOP_01116 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AIIGCJOP_01117 7.3e-155 rlmJ 2.1.1.266 S Specifically methylates the adenine in position 2030 of 23S rRNA
AIIGCJOP_01118 0.0 prlC 3.4.15.5, 3.4.24.70 E oligopeptidase
AIIGCJOP_01119 3.7e-134 rsmJ 2.1.1.242 J Specifically methylates the guanosine in position 1516 of 16S rRNA
AIIGCJOP_01120 2.3e-75 uspA T Required for resistance to DNA-damaging agents
AIIGCJOP_01121 2.4e-56 uspB S Universal stress protein B
AIIGCJOP_01122 2.5e-267 pitA P phosphate transporter
AIIGCJOP_01123 2.7e-225 yhiN S HI0933 family
AIIGCJOP_01124 9.4e-52 P Ion channel
AIIGCJOP_01125 6.3e-185 terC P membrane protein, terc
AIIGCJOP_01126 1.1e-121 cicA 2.3.1.51, 3.1.3.27, 3.1.3.3 E Hydrolase
AIIGCJOP_01127 1.1e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_01128 2.5e-126 IV02_08490 K LysR substrate binding domain
AIIGCJOP_01129 9e-92 padC Q Phenolic acid decarboxylase (PAD)
AIIGCJOP_01130 3.4e-95 sfp 2.7.8.7 H Belongs to the P-Pant transferase superfamily
AIIGCJOP_01131 5.9e-25 fabF2 2.3.1.179 H Belongs to the beta-ketoacyl-ACP synthases family
AIIGCJOP_01132 4e-182 yhhT T permease
AIIGCJOP_01133 8.7e-202 yhhS EGP MFS-type transporter
AIIGCJOP_01134 2.6e-92 dcrB S dcrb protein
AIIGCJOP_01135 6.9e-116 yhhQ U Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AIIGCJOP_01136 1.4e-37 tusA J Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin
AIIGCJOP_01137 1.8e-173 yiaO G Bacterial extracellular solute-binding protein, family 7
AIIGCJOP_01138 4.1e-84 dctQ G Tripartite ATP-independent periplasmic transporter, DctQ
AIIGCJOP_01139 2.4e-218 dctM G TRAP-type C4-dicarboxylate transport system, large permease component
AIIGCJOP_01140 0.0 zntA 3.6.3.3, 3.6.3.5 P P-type atpase
AIIGCJOP_01141 5e-108 yhhN S YhhN family
AIIGCJOP_01142 1.2e-21 yhhM S Protein of unknown function (DUF2500)
AIIGCJOP_01143 2.3e-44 yhhL S Protein of unknown function (DUF1145)
AIIGCJOP_01144 9.1e-107 rsmD 2.1.1.171 L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle
AIIGCJOP_01145 1.6e-165 ftsY D Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components
AIIGCJOP_01146 4.2e-121 ftsE D cell division ATP-binding protein FtsE
AIIGCJOP_01147 1e-185 ftsX D Part of the ABC transporter FtsEX involved in cellular division
AIIGCJOP_01148 1.5e-155 rpoH K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes
AIIGCJOP_01149 3.9e-201 livJ E With LivFGHM is involved in the high affinity leucine transport
AIIGCJOP_01151 6.8e-200 licB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
AIIGCJOP_01152 3.5e-135 yvaA 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
AIIGCJOP_01153 6.6e-79 O peptidase U32
AIIGCJOP_01154 1.3e-64 K Transcriptional regulator
AIIGCJOP_01155 2.3e-58 panZ K Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion
AIIGCJOP_01156 5.6e-203 livK E With LivFGHM is involved in the high affinity leucine transport
AIIGCJOP_01157 1.8e-146 livH P Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_01158 6.2e-214 livM E Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_01159 4.6e-140 livG E Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids
AIIGCJOP_01160 1.2e-126 livF P Branched-chain amino acid transport
AIIGCJOP_01161 8.7e-31 D Antitoxin component of a toxin-antitoxin (TA) module
AIIGCJOP_01162 4.4e-56 doc S Death ON curing protein
AIIGCJOP_01163 7.7e-252 ugpB G Bacterial extracellular solute-binding protein
AIIGCJOP_01164 3.3e-158 ugpA P With UgpEC is involved in the uptake of glycerol-3-phosphate
AIIGCJOP_01165 3.9e-148 ugpE P probably responsible for the translocation of the substrate across the membrane
AIIGCJOP_01166 1.1e-200 ugpC 3.6.3.20 P Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system
AIIGCJOP_01167 1.4e-133 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AIIGCJOP_01168 7.7e-19 yhhA S Protein of unknown function (DUF2756)
AIIGCJOP_01169 0.0 ggt 2.3.2.2, 3.4.19.13 M Gamma-glutamyltransferase
AIIGCJOP_01170 1.2e-72 speG_2 K PFAM GCN5-related N-acetyltransferase
AIIGCJOP_01171 1.5e-54 M COG1664 Integral membrane protein CcmA involved in cell shape determination
AIIGCJOP_01172 1.5e-194 yhhX 1.1.1.371 S oxidoreductase
AIIGCJOP_01173 1.6e-131 yhhW S Belongs to the pirin family
AIIGCJOP_01174 2e-183 gntR K Periplasmic binding protein LacI transcriptional regulator
AIIGCJOP_01175 1.1e-92 gntK 2.7.1.12 F Gluconokinase
AIIGCJOP_01176 1.3e-230 gntU EG Gluconate
AIIGCJOP_01177 7.1e-96 yhgN U UPF0056 membrane protein
AIIGCJOP_01178 4.7e-210 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AIIGCJOP_01179 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AIIGCJOP_01180 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
AIIGCJOP_01181 6.2e-246 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AIIGCJOP_01182 1.6e-271 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
AIIGCJOP_01183 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AIIGCJOP_01184 2.9e-287 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AIIGCJOP_01185 8e-57 glpE 2.8.1.1 P Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide
AIIGCJOP_01186 2.2e-151 glpG S Rhomboid-type serine protease that catalyzes intramembrane proteolysis
AIIGCJOP_01187 7.6e-135 glpR K transcriptional regulator
AIIGCJOP_01188 0.0 malT K Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'
AIIGCJOP_01189 0.0 malP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AIIGCJOP_01190 0.0 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
AIIGCJOP_01191 3.5e-220 gntT EG Gluconate
AIIGCJOP_01192 1.8e-104 nfuA C Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AIIGCJOP_01193 6.9e-103 comF S Competence protein
AIIGCJOP_01194 5.9e-127 bioH 2.1.1.197, 3.1.1.85 S The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters
AIIGCJOP_01195 4.4e-37 yahO S Protein of unknown function (DUF1471)
AIIGCJOP_01196 2.6e-33 feoC K metal cluster binding
AIIGCJOP_01197 0.0 feoB P Transporter of a GTP-driven Fe(2 ) uptake system
AIIGCJOP_01198 2.8e-32 feoA P FeoA domain
AIIGCJOP_01199 0.0 yhgF K accessory protein
AIIGCJOP_01200 1.4e-83 greB K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length
AIIGCJOP_01201 5.7e-132 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_01202 1.4e-248 T PhoQ Sensor
AIIGCJOP_01203 2.2e-311 pckA 4.1.1.49 H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AIIGCJOP_01204 9e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AIIGCJOP_01205 1.8e-66 hslR J Belongs to the HSP15 family
AIIGCJOP_01206 1.2e-126 yrfG 3.1.3.5 S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3
AIIGCJOP_01207 0.0 yrfF S Intracellular growth attenuator
AIIGCJOP_01208 1.9e-98 nudE L Hydrolase
AIIGCJOP_01209 0.0 mrcA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
AIIGCJOP_01210 1.1e-125 hofM NU Pilus assembly protein
AIIGCJOP_01211 7e-58 hofN NU carbon utilization
AIIGCJOP_01212 1.3e-49 hofO S carbon utilization
AIIGCJOP_01213 1.1e-188 pilQ U (Type IV) pilus
AIIGCJOP_01214 3.3e-89 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AIIGCJOP_01215 2e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AIIGCJOP_01216 8.3e-110 damX D Cell division protein DamX
AIIGCJOP_01217 2.8e-143 dam 2.1.1.72 H Site-specific DNA-methyltransferase (adenine-specific)
AIIGCJOP_01218 5.9e-123 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AIIGCJOP_01219 1.2e-132 gph 3.1.3.18 G Phosphoglycolate phosphatase
AIIGCJOP_01220 3.9e-187 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
AIIGCJOP_01221 1.6e-24 yhfL S Protein of unknown function (DUF4223)
AIIGCJOP_01222 1.5e-253 cysG 1.3.1.76, 2.1.1.107, 2.1.1.131, 3.7.1.12, 4.2.1.75, 4.99.1.3, 4.99.1.4 H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AIIGCJOP_01223 1.9e-147 nirC P nitrite transporter
AIIGCJOP_01224 1.8e-56 nirD 1.7.1.15 P Nitrite reductase
AIIGCJOP_01225 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AIIGCJOP_01226 1e-248 codA 3.5.4.1 F cytosine deaminase
AIIGCJOP_01227 6.6e-210 tsgA G Protein tsgA homolog
AIIGCJOP_01228 1.3e-94 ppiA 5.2.1.8 M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AIIGCJOP_01229 1.4e-107 fic D cell filamentation protein Fic
AIIGCJOP_01230 3.4e-100 pabA 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate synthase
AIIGCJOP_01231 1.5e-230 argD 2.6.1.11, 2.6.1.17, 2.6.1.81 E aminotransferase
AIIGCJOP_01232 0.0 yhfK S integral membrane protein, YccS YhfK family
AIIGCJOP_01233 1.9e-115 crp K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AIIGCJOP_01234 2.1e-67 yhfA O Redox protein regulator of disulfide bond formation
AIIGCJOP_01235 8e-165 prkB 2.7.1.19 G Phosphoribulokinase
AIIGCJOP_01236 2.4e-33 yheU S Belongs to the UPF0270 family
AIIGCJOP_01237 3.3e-178 yheT S PFAM Alpha beta hydrolase
AIIGCJOP_01238 0.0 mdcA 2.3.1.187 I Malonate decarboxylase
AIIGCJOP_01239 8.3e-146 mdcB 2.4.2.52 H Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase
AIIGCJOP_01240 1.4e-44 mdcC C Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism
AIIGCJOP_01241 5.4e-150 mdcD 4.1.1.87 I Beta subunit
AIIGCJOP_01242 5.4e-139 mdcE 4.1.1.87 I Malonate decarboxylase gamma subunit
AIIGCJOP_01243 3e-160 mdcF S auxin efflux carrier
AIIGCJOP_01244 1e-89 mdcG 2.7.7.66 H Phosphoribosyl-dephospho-CoA transferase MdcG
AIIGCJOP_01245 3e-146 mdcH 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AIIGCJOP_01246 3.5e-166 mdcR K transcriptional regulator
AIIGCJOP_01247 0.0 yheS S ABC transporter
AIIGCJOP_01248 7.5e-100 kefG S Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB
AIIGCJOP_01249 2.6e-306 kefB P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AIIGCJOP_01250 1.6e-31 yheV S Probable metal-binding protein (DUF2387)
AIIGCJOP_01251 5e-78 slyD 5.2.1.8 G Peptidyl-prolyl cis-trans
AIIGCJOP_01252 8.9e-28 slyX S Belongs to the SlyX family
AIIGCJOP_01253 1.6e-130 fkpA 5.2.1.8 M Peptidyl-prolyl cis-trans
AIIGCJOP_01254 1.8e-130 yheO S protein conserved in bacteria
AIIGCJOP_01255 1.4e-63 tusD P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AIIGCJOP_01256 4.8e-47 tusC J Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions
AIIGCJOP_01257 3.6e-37 tusB J Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions
AIIGCJOP_01258 1.6e-64 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AIIGCJOP_01259 6.2e-79 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center
AIIGCJOP_01260 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AIIGCJOP_01261 3e-92 L HTH-like domain
AIIGCJOP_01262 0.0 V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AIIGCJOP_01263 2.2e-150 M Secretion Protein
AIIGCJOP_01264 9.7e-167 kamA 5.4.3.2 C 4Fe-4S single cluster domain
AIIGCJOP_01265 7.5e-103 efp J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of
AIIGCJOP_01266 2.8e-08 ecnA S Entericidin EcnA/B family
AIIGCJOP_01267 1.9e-13 ecnB S Entericidin
AIIGCJOP_01268 1.1e-93 ecnR K regulatory protein
AIIGCJOP_01269 1.8e-45 sugE U multidrug resistance protein
AIIGCJOP_01270 3.3e-84 blc M Outer Membrane Lipoprotein
AIIGCJOP_01271 1.7e-60 frdD C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AIIGCJOP_01272 1.9e-68 frdC C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AIIGCJOP_01273 8.1e-142 frdB 1.3.5.1, 1.3.5.4 C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AIIGCJOP_01274 0.0 frdA 1.3.5.1, 1.3.5.4 C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily
AIIGCJOP_01275 3e-184 epmA J With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AIIGCJOP_01276 0.0 yjeP M mechanosensitive ion channel
AIIGCJOP_01277 6.4e-179 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
AIIGCJOP_01278 4.6e-194 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AIIGCJOP_01279 9.7e-100 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
AIIGCJOP_01283 5.3e-217 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AIIGCJOP_01284 1.1e-222 nnrD 4.2.1.136, 5.1.99.6 H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AIIGCJOP_01285 4e-78 yjeE S ATPase or kinase
AIIGCJOP_01286 6e-228 amiB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AIIGCJOP_01287 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AIIGCJOP_01288 7.2e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AIIGCJOP_01289 3.1e-34 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
AIIGCJOP_01290 2.4e-234 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AIIGCJOP_01291 1.4e-165 hflK O HflC and HflK could encode or regulate a protease
AIIGCJOP_01292 7.9e-140 hflC O HflC and HflK could regulate a protease
AIIGCJOP_01293 5.1e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AIIGCJOP_01294 1.3e-70 nsrR K Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity
AIIGCJOP_01295 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AIIGCJOP_01296 1.3e-131 rlmB 2.1.1.185, 2.1.1.34 J Specifically methylates the ribose of guanosine 2251 in 23S rRNA
AIIGCJOP_01297 6.9e-221 EGP Major facilitator superfamily
AIIGCJOP_01298 3.5e-307 aidB I acyl-CoA dehydrogenase
AIIGCJOP_01299 1.2e-64 NT Single cache domain 3
AIIGCJOP_01300 1.9e-223 NT chemotaxis, protein
AIIGCJOP_01301 4.8e-39 yjfN S Protein of unknown function (DUF1471)
AIIGCJOP_01302 2.2e-18 bsmA CO response to hydrogen peroxide
AIIGCJOP_01303 4.3e-127 yjfP S esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro
AIIGCJOP_01304 3.2e-133 ulaR K transcriptional regulator
AIIGCJOP_01305 1.1e-216 ulaG S Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions
AIIGCJOP_01306 1.3e-254 ulaA 2.7.1.194 S PTS system sugar-specific permease component
AIIGCJOP_01307 2e-49 ulaB 2.7.1.194 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport
AIIGCJOP_01308 2.8e-79 ulaC 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AIIGCJOP_01309 7.5e-115 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
AIIGCJOP_01310 2.6e-155 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
AIIGCJOP_01311 1.3e-125 ulaF 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 G Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate
AIIGCJOP_01312 2e-40 yjfY S Protein of unknown function (DUF1471)
AIIGCJOP_01313 7.9e-67 rpsF 4.3.1.19 J Binds together with S18 to 16S ribosomal RNA
AIIGCJOP_01314 3.9e-53 priB L Binds single-stranded DNA at the primosome assembly site (PAS)
AIIGCJOP_01315 1.3e-34 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AIIGCJOP_01316 1.2e-71 rplI J binds to the 23S rRNA
AIIGCJOP_01317 3.9e-165 CP_1064 EG transporter
AIIGCJOP_01318 7.4e-107 ytfB M Opacity-associated protein A
AIIGCJOP_01319 3.8e-108 fklB 5.2.1.8 O Peptidyl-prolyl cis-trans
AIIGCJOP_01320 1.1e-253 cycA E amino acid
AIIGCJOP_01321 4.3e-118 ytfE D Di-iron-containing protein involved in the repair of iron-sulfur clusters
AIIGCJOP_01322 4.5e-148 tar NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
AIIGCJOP_01323 7.8e-169 ytfF EG Permeases of the drug metabolite transporter (DMT) superfamily
AIIGCJOP_01324 7.6e-157 K transcriptional regulator
AIIGCJOP_01325 3e-140 ytfG 1.6.5.2 GM NmrA family
AIIGCJOP_01326 1.1e-62 ytfH K transcriptional regulator
AIIGCJOP_01327 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AIIGCJOP_01328 7.4e-135 cysQ 3.1.3.7 P 3'(2'),5'-bisphosphate nucleotidase
AIIGCJOP_01329 1.1e-90 ytfJ S transcriptional regulator
AIIGCJOP_01330 5.2e-30 ytfK S Protein of unknown function (DUF1107)
AIIGCJOP_01331 5.5e-221 ytfL P Hemolysins and related proteins containing CBS domains
AIIGCJOP_01332 8.7e-116 msrA 1.8.4.11 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AIIGCJOP_01333 0.0 ytfM M COG0729 Outer membrane protein
AIIGCJOP_01334 0.0 ytfN M protein conserved in bacteria
AIIGCJOP_01335 1.1e-59 ytfP S AIG2 family
AIIGCJOP_01336 1.5e-97 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AIIGCJOP_01337 1.8e-165 ytfQ G Periplasmic binding protein domain
AIIGCJOP_01338 6.9e-273 ytfR 3.6.3.17 P import. Responsible for energy coupling to the transport system
AIIGCJOP_01339 1e-171 ytfT G Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_01340 6.6e-171 yjfF P Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_01341 4.4e-169 tar NT chemotaxis, protein
AIIGCJOP_01342 5.5e-32 K Bacterial regulatory helix-turn-helix protein, lysR family
AIIGCJOP_01343 7e-189 fbp 3.1.3.11 G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AIIGCJOP_01344 1.2e-263 murC 6.3.2.4, 6.3.2.45, 6.3.2.8 M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate
AIIGCJOP_01345 6.4e-91 yjgA S Belongs to the UPF0307 family
AIIGCJOP_01346 2.1e-244 pmbA S Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD
AIIGCJOP_01347 3e-55 cybC C Cytochrome b(562)
AIIGCJOP_01349 7.2e-53 S PRD domain protein
AIIGCJOP_01350 2.6e-61 S Glycine-rich SFCGS
AIIGCJOP_01351 7.6e-46 S Domain of unknown function (DUF4312)
AIIGCJOP_01352 1.4e-139 S Domain of unknown function (DUF4311)
AIIGCJOP_01353 6.5e-103 S Membrane
AIIGCJOP_01354 1.6e-205 dho 3.5.2.3 S Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
AIIGCJOP_01355 2.9e-199 selA 2.9.1.1 E PFAM aromatic amino acid beta-eliminating lyase threonine aldolase
AIIGCJOP_01356 1.9e-130 4.1.2.14 S 2-dehydro-3-deoxyphosphooctonate aldolase
AIIGCJOP_01357 7.5e-179 ykgB 3.1.1.31 G COG2706 3-carboxymuconate cyclase
AIIGCJOP_01358 0.0 licR 2.7.1.197 GK transcriptional antiterminator
AIIGCJOP_01359 4.1e-34 relB L RelB antitoxin
AIIGCJOP_01360 2.7e-37 relE DJ ParE toxin of type II toxin-antitoxin system, parDE
AIIGCJOP_01361 1.4e-86 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AIIGCJOP_01362 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AIIGCJOP_01363 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AIIGCJOP_01364 1.6e-258 treB 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AIIGCJOP_01365 4.4e-164 treR K trehalose
AIIGCJOP_01366 0.0 mgtA 3.6.3.2 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
AIIGCJOP_01367 0.0 nahA 3.2.1.52 GH20 G PFAM Glycoside hydrolase, family 20
AIIGCJOP_01368 7.9e-258 gbpA AA10,CBM73 E Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin
AIIGCJOP_01369 9.7e-62 ridA 3.5.99.10 J PFAM Endoribonuclease L-PSP
AIIGCJOP_01370 2.2e-81 pyrI 2.1.3.2 F Involved in allosteric regulation of aspartate carbamoyltransferase
AIIGCJOP_01371 2.2e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AIIGCJOP_01372 1.6e-76 tabA G Toxin-antitoxin biofilm protein TabA
AIIGCJOP_01373 1e-154 yagE 4.1.2.28, 4.1.3.3, 4.3.3.7 EM Belongs to the DapA family
AIIGCJOP_01374 0.0 yagF 4.2.1.82 EG Belongs to the IlvD Edd family
AIIGCJOP_01375 8.9e-251 yagG G COG2211 Na melibiose symporter and related transporters
AIIGCJOP_01376 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
AIIGCJOP_01377 3e-131 yagI K transcriptional regulator
AIIGCJOP_01378 1.2e-21 iraM S Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation
AIIGCJOP_01379 6.6e-187 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AIIGCJOP_01380 2.7e-65 rraB S Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AIIGCJOP_01381 9.6e-138 miaE FJ tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)
AIIGCJOP_01382 1.1e-101
AIIGCJOP_01384 1.5e-180 metAS 2.3.1.46 E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine
AIIGCJOP_01385 1.2e-307 aceB 2.3.3.9 C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AIIGCJOP_01386 1e-243 aceA 4.1.3.1 C Isocitrate lyase
AIIGCJOP_01387 0.0 aceK 2.7.11.5 F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation
AIIGCJOP_01388 1.9e-147 iclR K transcriptional regulator
AIIGCJOP_01389 0.0 metH 2.1.1.13 E methionine synthase
AIIGCJOP_01390 1.7e-277 yjbB P Na Pi-Cotransporter
AIIGCJOP_01391 1.6e-42 K Phage derived protein Gp49-like (DUF891)
AIIGCJOP_01392 1.4e-35 K conserved small protein
AIIGCJOP_01393 1.1e-158 rluF 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AIIGCJOP_01394 2.1e-39 yjbD S YjbD family (DUF3811)
AIIGCJOP_01395 2.6e-148 yocS S Bile acid sodium symporter
AIIGCJOP_01396 1.6e-231 rtcR K regulates genes involved in forming a 2',3'-cyclic phosphodiester on RNA
AIIGCJOP_01397 2.2e-27 rtcR K regulates genes involved in forming a 2',3'-cyclic phosphodiester on RNA
AIIGCJOP_01398 3.1e-231 rtcB 6.5.1.3 S Belongs to the RtcB family
AIIGCJOP_01399 2.5e-234 lysC 1.1.1.3, 2.7.2.4, 4.1.1.20 E Belongs to the aspartokinase family
AIIGCJOP_01400 0.0 pgi 5.3.1.9 G Belongs to the GPI family
AIIGCJOP_01401 8.4e-64 psiE S Protein PsiE homolog
AIIGCJOP_01402 1.4e-159 malG P transport
AIIGCJOP_01403 8.6e-287 malF P transport
AIIGCJOP_01404 5e-226 malE G Functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis
AIIGCJOP_01405 2.4e-206 malK P Belongs to the ABC transporter superfamily
AIIGCJOP_01406 5e-251 lamB M involved in the transport of maltose and maltodextrins
AIIGCJOP_01407 4.8e-142 malM S maltose operon periplasmic
AIIGCJOP_01408 2.8e-85 ubiC 4.1.3.40 H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway
AIIGCJOP_01409 2.1e-141 ubiA 2.5.1.39 H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AIIGCJOP_01410 0.0 plsB 2.3.1.15 I Belongs to the GPAT DAPAT family
AIIGCJOP_01411 1.6e-58 dgkA 2.7.1.107 M Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AIIGCJOP_01412 1.1e-107 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AIIGCJOP_01413 2.3e-219 dinF V COG0534 Na -driven multidrug efflux pump
AIIGCJOP_01414 3.1e-33 yjbJ S Belongs to the UPF0337 (CsbD) family
AIIGCJOP_01415 4.3e-89 zur P belongs to the Fur family
AIIGCJOP_01416 6e-93 manC S Cupin domain
AIIGCJOP_01417 6.8e-192 traF S transfer protein
AIIGCJOP_01418 3.5e-188 dusA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs
AIIGCJOP_01419 2.3e-29 pspG S Phage Shock Protein G
AIIGCJOP_01420 8.5e-179 qor 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
AIIGCJOP_01421 3.6e-263 dnaB 3.6.4.12 L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins
AIIGCJOP_01422 1.1e-198 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AIIGCJOP_01424 5.6e-225 tyrB 2.6.1.1, 2.6.1.57 E aminotransferase
AIIGCJOP_01425 5.3e-74 yjbQ S Secondary thiamine-phosphate synthase enzyme
AIIGCJOP_01426 5.4e-59 yjbR S protein conserved in bacteria
AIIGCJOP_01427 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AIIGCJOP_01428 1.6e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AIIGCJOP_01429 2.8e-42 yjcB S membrane
AIIGCJOP_01430 4.1e-219 T Diguanylate cyclase
AIIGCJOP_01431 4.4e-270 yjcC 3.1.4.52 T signal transduction protein containing sensor and EAL
AIIGCJOP_01432 1.4e-53 soxS K transcriptional regulator
AIIGCJOP_01433 1.8e-78 soxR K redox-sensitive transcriptional activator SoxR
AIIGCJOP_01434 9.4e-113 gstA 2.5.1.18 O Belongs to the GST superfamily
AIIGCJOP_01435 6.1e-228 yjcD S permease
AIIGCJOP_01436 2.2e-288 yjcE P NhaP-type Na H and K H antiporters
AIIGCJOP_01437 1.8e-164 ywbI K transcriptional regulator
AIIGCJOP_01438 4.5e-65 cidA S LrgA family
AIIGCJOP_01439 1.3e-117 ywbG M effector of murein hydrolase
AIIGCJOP_01440 5.9e-233 G ABC transporter substrate-binding protein
AIIGCJOP_01441 1.4e-242 yteT S oxidoreductase
AIIGCJOP_01442 8.5e-290 3.2.1.139 G Belongs to the glycosyl hydrolase 67 family
AIIGCJOP_01443 7.3e-292 actP P Cation acetate symporter ActP
AIIGCJOP_01444 4.5e-49 yjcH S Protein of unknown function, DUF485
AIIGCJOP_01445 0.0 acsA 6.2.1.1 I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AIIGCJOP_01446 1.3e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AIIGCJOP_01447 5.2e-79 yjcO S Sel1 repeat
AIIGCJOP_01448 4.7e-311 fdhF 1.17.1.10, 1.17.1.9, 1.17.99.7 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_01449 1.3e-67 fdhF 1.17.1.10, 1.17.1.9, 1.17.99.7 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_01450 4.2e-122 K response regulator
AIIGCJOP_01451 1.1e-178 2.7.1.15, 2.7.1.4 G PfkB domain protein
AIIGCJOP_01452 2.7e-152 4.1.2.13 G Aldolase
AIIGCJOP_01453 7.3e-129 5.3.1.15 S D-lyxose isomerase
AIIGCJOP_01454 1.3e-165 rbsB G PFAM Periplasmic binding protein LacI transcriptional regulator
AIIGCJOP_01455 5.8e-167 MA20_14255 U Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_01456 1e-276 rbsA 3.6.3.17 P import. Responsible for energy coupling to the transport system
AIIGCJOP_01457 0.0 virA T Histidine kinase
AIIGCJOP_01458 5e-100
AIIGCJOP_01459 1.6e-09
AIIGCJOP_01460 8.9e-144 phnP 3.1.4.55 S Carbon-phosphorus lyase complex accessory protein
AIIGCJOP_01461 1.6e-73 phnO K Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role
AIIGCJOP_01462 2.7e-89 phnN 2.7.4.23 F Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AIIGCJOP_01463 1.5e-203 phnM 3.6.1.63 P phosphonate metabolism protein PhnM
AIIGCJOP_01464 1.5e-121 phnL 2.7.8.37 P phosphonate C-P lyase system protein PhnL
AIIGCJOP_01465 1.5e-135 phnK 4.7.1.1 P Phosphonate C-P lyase
AIIGCJOP_01466 5.8e-160 phnJ 4.7.1.1 H Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose
AIIGCJOP_01467 5e-185 phnI 2.7.8.37 P Phosphonate
AIIGCJOP_01468 4.7e-100 phnH 2.7.8.37 P phosphonate C-P lyase system protein PhnH
AIIGCJOP_01469 1.2e-71 phnG 2.7.8.37 P Phosphonate C-P lyase system protein PhnG
AIIGCJOP_01470 8.3e-131 phnF K Transcriptional regulator
AIIGCJOP_01471 2.8e-140 phnE 3.6.1.63 P Phosphonate ABC transporter
AIIGCJOP_01472 7.9e-180 phnD P Phosphonate ABC transporter
AIIGCJOP_01473 2.6e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AIIGCJOP_01474 2.8e-57 phnA P Alkylphosphonate utilization operon protein PhnA
AIIGCJOP_01475 0.0 yjdA S chromosome segregation
AIIGCJOP_01476 3.1e-148 yjcZ S YjcZ-like protein
AIIGCJOP_01477 2.1e-148 kdgT U The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
AIIGCJOP_01478 3.4e-272 proP EGP transporter
AIIGCJOP_01479 7.3e-224 wcaJ M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
AIIGCJOP_01480 1.2e-244 S Putative beta-barrel porin 2
AIIGCJOP_01481 9e-93 M COG1596 Periplasmic protein involved in polysaccharide export
AIIGCJOP_01482 1.7e-293 ywqD 2.7.10.1, 2.7.10.2 D protein involved in exopolysaccharide biosynthesis
AIIGCJOP_01483 2.6e-198 wzx S polysaccharide biosynthetic process
AIIGCJOP_01484 9.9e-218
AIIGCJOP_01485 8.9e-176 M PFAM Glycosyl transferase family 2
AIIGCJOP_01486 5.1e-210 M glycosyl transferase group 1
AIIGCJOP_01487 5.6e-195 M PFAM Glycosyl transferase, group 1
AIIGCJOP_01488 7.1e-63
AIIGCJOP_01489 9.5e-156 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AIIGCJOP_01490 1.5e-245 G Domain of unknown function (DUF4832)
AIIGCJOP_01491 4.3e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AIIGCJOP_01492 0.0 btuB P Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB
AIIGCJOP_01493 4.1e-206 trmA 2.1.1.190, 2.1.1.35 J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)
AIIGCJOP_01494 2.7e-58 yijD S membrane
AIIGCJOP_01495 1.5e-107 fabR K Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer
AIIGCJOP_01496 2.1e-271 sthA 1.6.1.1 C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation
AIIGCJOP_01497 2.8e-168 oxyR K Transcriptional regulator
AIIGCJOP_01498 1e-254 argH 2.3.1.1, 4.3.2.1 E argininosuccinate lyase
AIIGCJOP_01499 1.5e-138 argB 2.3.1.1, 2.7.2.8 E Catalyzes the ATP-dependent phosphorylation of N-acetyl- L-glutamate
AIIGCJOP_01500 9.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AIIGCJOP_01501 2e-227 argE 3.5.1.16 E Belongs to the peptidase M20A family. ArgE subfamily
AIIGCJOP_01502 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AIIGCJOP_01503 1.8e-99 yijO K Transcriptional regulator
AIIGCJOP_01504 1.1e-102 tal 2.2.1.2 H Catalyzes the reversible formation of fructose 6- phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction
AIIGCJOP_01505 1.8e-198 gldA 1.1.1.6 C glycerol dehydrogenase
AIIGCJOP_01506 0.0 katG 1.11.1.21 P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AIIGCJOP_01507 2.2e-170 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
AIIGCJOP_01508 0.0 metL 1.1.1.3, 2.7.2.4 E belongs to the aspartokinase family
AIIGCJOP_01509 2.9e-218 metB 2.5.1.48, 4.4.1.8 E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide
AIIGCJOP_01510 1e-53 metJ K This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AIIGCJOP_01511 1.9e-35 rpmE J Binds the 23S rRNA
AIIGCJOP_01512 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AIIGCJOP_01513 7.1e-175 cytR K transcriptional
AIIGCJOP_01514 8.2e-101 ftsN D Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases
AIIGCJOP_01515 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AIIGCJOP_01516 3e-243 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AIIGCJOP_01517 1.6e-158 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
AIIGCJOP_01518 3.2e-86 rraA H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AIIGCJOP_01520 6.5e-32 zapB 2.1.1.80, 3.1.1.61 D Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA
AIIGCJOP_01521 2.2e-146 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AIIGCJOP_01522 4.9e-295 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AIIGCJOP_01523 2.1e-180 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Fructose-1,6-bisphosphatase
AIIGCJOP_01524 5.4e-117 fpr 1.18.1.2, 1.19.1.1 C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
AIIGCJOP_01525 3.3e-71 yiiR S Membrane
AIIGCJOP_01526 1.2e-82 yiiQ S Protein of unknown function (DUF1454)
AIIGCJOP_01527 9e-136 tpiA 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AIIGCJOP_01528 6.3e-230 P Citrate transporter
AIIGCJOP_01529 6.6e-123 cdh 3.6.1.26 I CDP-diacylglycerol pyrophosphatase
AIIGCJOP_01530 5.2e-184 sbp P sulfate ABC transporter
AIIGCJOP_01531 1.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
AIIGCJOP_01532 4.8e-160 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AIIGCJOP_01533 1.8e-76 cpxP NPTU Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA
AIIGCJOP_01534 1.1e-124 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_01535 6.4e-249 T PhoQ Sensor
AIIGCJOP_01536 6.9e-119 yiiM S MOSC domain containing protein
AIIGCJOP_01537 3.8e-116 sodA 1.15.1.1 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AIIGCJOP_01538 1.5e-152 rhaR K Activates expression of the rhaSR operon in response to L-rhamnose
AIIGCJOP_01539 4.1e-158 rhaS K Activates expression of the rhaBAD and rhaT operons
AIIGCJOP_01540 1.7e-271 rhaB 2.7.1.17, 2.7.1.189, 2.7.1.5, 2.7.1.51, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
AIIGCJOP_01541 5.8e-241 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase
AIIGCJOP_01542 1.3e-156 rhaD 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
AIIGCJOP_01543 5.3e-173 rhaS G (ABC) transporter
AIIGCJOP_01544 1.9e-275 rbsA 3.6.3.17 P import. Responsible for energy coupling to the transport system
AIIGCJOP_01545 1.5e-170 rhaP U Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_01546 2.4e-165 rhaQ U Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_01547 2.2e-202 fucO 1.1.1.1 C alcohol dehydrogenase
AIIGCJOP_01548 2.3e-53 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
AIIGCJOP_01549 8.6e-232 lacY G Major facilitator superfamily
AIIGCJOP_01550 0.0 rafA 3.2.1.22 G alpha-galactosidase
AIIGCJOP_01551 2.9e-174 aglR K PFAM Periplasmic binding protein LacI transcriptional regulator
AIIGCJOP_01552 2.3e-93 sinR K Transcriptional regulator
AIIGCJOP_01553 2.7e-112 azlC E branched-chain amino acid
AIIGCJOP_01554 3.8e-43 S Branched-chain amino acid transport protein (AzlD)
AIIGCJOP_01555 1.4e-25 S Protein of unknown function (DUF1471)
AIIGCJOP_01556 3e-132 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AIIGCJOP_01557 8e-108 fdoG 1.17.1.9, 1.17.5.3 C PFAM Molybdopterin oxidoreductase Fe4S4 region
AIIGCJOP_01558 0.0 fdoG 1.17.1.9, 1.17.5.3 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_01559 5.8e-182 fdoH C TIGRFAM formate dehydrogenase, beta subunit
AIIGCJOP_01560 1.7e-116 fdoI C formate dehydrogenase
AIIGCJOP_01561 2e-174 fdhE O Necessary for formate dehydrogenase activity
AIIGCJOP_01562 2.8e-07 pagC M Membrane
AIIGCJOP_01563 3.2e-186 yiiD K Putative thioesterase (yiiD_Cterm)
AIIGCJOP_01564 1.9e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AIIGCJOP_01565 1.4e-120 rbn K UPF0761 membrane protein
AIIGCJOP_01566 3.8e-105 yihX 3.1.3.10 S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3
AIIGCJOP_01567 9.1e-139 yihW K Transcriptional regulator
AIIGCJOP_01568 2.5e-153 yihV 2.7.1.15, 2.7.1.184 G Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6- deoxy-6-sulfo-D-fructose 1-phosphate (SFP)
AIIGCJOP_01569 1.4e-156 yihU 1.1.1.373, 1.1.1.411, 1.1.1.61 C Reduces 3-sulfolactaldehyde (SLA) to 2,3- dihydroxypropane 1-sulfonate (DHPS)
AIIGCJOP_01570 1.5e-155 lacD 4.1.2.40, 4.1.2.57 G Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA)
AIIGCJOP_01571 4.1e-255 yihS 5.1.3.11, 5.3.1.31 G Catalyzes the isomerization of sulfoquinovose (SQ) to 6- deoxy-6-sulfo-D-fructose (SF)
AIIGCJOP_01572 0.0 yihQ 3.2.1.177, 3.2.1.199 GH31 G Belongs to the glycosyl hydrolase 31 family
AIIGCJOP_01573 2.7e-263 yihP G transporter
AIIGCJOP_01574 2.8e-263 yihO G transporter
AIIGCJOP_01575 9.3e-100 lptD M Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is
AIIGCJOP_01576 0.0 typA T GTP-binding protein
AIIGCJOP_01577 1.8e-275 glnA 5.4.4.3, 6.3.1.2 E glutamine synthetase
AIIGCJOP_01578 7.6e-194 glnL 2.7.13.3 T Signal transduction histidine kinase, nitrogen specific
AIIGCJOP_01579 8.8e-270 glnG T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
AIIGCJOP_01580 2.8e-260 hemN 1.3.98.3 H Belongs to the anaerobic coproporphyrinogen-III oxidase family
AIIGCJOP_01581 2.7e-43 yihI S A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis
AIIGCJOP_01582 9.4e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
AIIGCJOP_01583 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AIIGCJOP_01584 2.5e-153 yihG I Acyltransferase
AIIGCJOP_01585 1.3e-111 dsbA O Thiol disulfide interchange protein
AIIGCJOP_01586 8.8e-184 srkA F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AIIGCJOP_01587 1.7e-41 yihD S protein conserved in bacteria
AIIGCJOP_01588 6.1e-76 mobA 2.10.1.1, 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
AIIGCJOP_01589 7.9e-72 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
AIIGCJOP_01590 3.5e-37 IQ Phosphopantetheine attachment site
AIIGCJOP_01591 3.6e-80 fabZ 4.2.1.59 I FabA-like domain
AIIGCJOP_01592 8.7e-107 IQ 3-oxoacyl- acyl-carrier-protein reductase
AIIGCJOP_01593 7.6e-40 acpS 2.7.8.7, 4.2.1.136 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AIIGCJOP_01594 6.6e-205 U hemolysin activation secretion protein
AIIGCJOP_01595 7e-176 U haemagglutination activity domain
AIIGCJOP_01596 3.5e-125 S alpha beta
AIIGCJOP_01597 0.0 S TIGRFAM outer membrane autotransporter barrel
AIIGCJOP_01598 3.6e-165 yghU O Belongs to the GST superfamily
AIIGCJOP_01600 3.9e-176 T Diguanylate cyclase
AIIGCJOP_01601 1.6e-126 fucR K transcriptional regulator
AIIGCJOP_01602 7.5e-198 tar NT chemotaxis, protein
AIIGCJOP_01603 0.0 S Autotransporter beta-domain
AIIGCJOP_01604 1.1e-161 yghX 3.1.1.45 Q dienelactone hydrolase
AIIGCJOP_01605 1e-198 yghZ C reductase
AIIGCJOP_01606 1.2e-80 yqhA S UPF0114 protein
AIIGCJOP_01607 8.1e-85
AIIGCJOP_01608 6.1e-67
AIIGCJOP_01609 5.7e-66
AIIGCJOP_01610 3.7e-157 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
AIIGCJOP_01611 6.9e-61 exbD U Biopolymer transport protein, ExbD
AIIGCJOP_01612 2.1e-118 exbB U tonB-system energizer ExbB
AIIGCJOP_01613 7e-220 metC 2.5.1.48, 4.4.1.11, 4.4.1.8 E cystathionine beta-lyase
AIIGCJOP_01614 8.9e-116 yghB S Pfam SNARE associated Golgi protein
AIIGCJOP_01615 3.3e-153 yqhC K transcriptional regulator
AIIGCJOP_01616 5.4e-217 yqhD C alcohol dehydrogenase
AIIGCJOP_01617 5e-156 dkgA 1.1.1.346 S reductase
AIIGCJOP_01618 0.0 ygiQ C UPF0313 protein
AIIGCJOP_01619 1.4e-238 trkH P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA
AIIGCJOP_01620 2e-269 ftsP D Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress
AIIGCJOP_01621 1.9e-127 plsC 2.3.1.51, 3.1.3.3 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
AIIGCJOP_01622 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AIIGCJOP_01623 2e-62 ygiW S PFAM conserved
AIIGCJOP_01624 1e-111 K response regulator
AIIGCJOP_01625 1.7e-209 qseC 2.7.13.3 T Integral membrane sensor signal transduction histidine kinase
AIIGCJOP_01626 3.4e-111 mdaB S modulator of drug activity B
AIIGCJOP_01627 8.8e-53 ygiN S monooxygenase
AIIGCJOP_01628 2.3e-75 ygaU S peptidoglycan-binding protein
AIIGCJOP_01629 9.4e-92
AIIGCJOP_01630 4e-231 ugl 3.2.1.180 GH88 S Hydrolase
AIIGCJOP_01631 6.9e-226 lacY P Major facilitator superfamily
AIIGCJOP_01632 0.0 S protein conserved in bacteria
AIIGCJOP_01633 2.3e-156 K AraC family transcriptional regulator
AIIGCJOP_01634 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AIIGCJOP_01635 3.9e-107 yqiA S esterase
AIIGCJOP_01636 1.6e-154 cpdA 2.1.2.2, 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AIIGCJOP_01637 1.2e-76 yqiB S Protein of unknown function (DUF1249)
AIIGCJOP_01638 2.7e-109 nudF 3.6.1.13 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
AIIGCJOP_01639 1.5e-213 tolC MU type I secretion outer membrane protein, TolC
AIIGCJOP_01640 6.3e-101 ygiB S Belongs to the UPF0441 family
AIIGCJOP_01641 1e-223 ygiC E Glutathionylspermidine synthase
AIIGCJOP_01642 2.8e-148 ygiD 1.13.11.8 C PFAM Extradiol ring-cleavage dioxygenase, class III
AIIGCJOP_01643 1.1e-117 zupT P Mediates zinc uptake. May also transport other divalent cations
AIIGCJOP_01644 5.9e-112 ribB 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AIIGCJOP_01645 7.3e-41 yqiC S protein conserved in bacteria
AIIGCJOP_01646 3.9e-265 hldE 2.7.1.167, 2.7.7.70 H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AIIGCJOP_01647 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
AIIGCJOP_01648 8.8e-224 ygiF 3.6.1.25 S Adenylate cyclase
AIIGCJOP_01649 1.3e-107 ygiM T sh3 domain protein
AIIGCJOP_01650 1.6e-230 cca 2.7.7.19, 2.7.7.72 F Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases
AIIGCJOP_01651 9.6e-144 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AIIGCJOP_01652 5.3e-57 folB 1.13.11.81, 4.1.2.25, 5.1.99.7, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AIIGCJOP_01653 9.9e-109 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AIIGCJOP_01654 4.2e-147 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AIIGCJOP_01655 2e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
AIIGCJOP_01656 1.1e-47 ureB 3.5.1.5 E Belongs to the urease beta subunit family
AIIGCJOP_01657 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AIIGCJOP_01658 4.9e-68 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AIIGCJOP_01659 4.6e-86 ureJ O urease accessory protein
AIIGCJOP_01660 3.8e-114 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AIIGCJOP_01661 8.1e-111 ureG H Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AIIGCJOP_01662 7.4e-233 chiA 3.2.1.14, 3.2.1.17 AA10,CBM15,CBM73,GH18 O Subtilase family
AIIGCJOP_01663 1.3e-66 K helix_turn_helix, Lux Regulon
AIIGCJOP_01664 8.7e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AIIGCJOP_01665 1.6e-29 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AIIGCJOP_01666 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AIIGCJOP_01667 0.0 rpoD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AIIGCJOP_01668 2.9e-90 mug 3.2.2.28, 6.3.3.2 L Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells
AIIGCJOP_01671 1.1e-40 K DNA-templated transcription, initiation
AIIGCJOP_01673 1.4e-67 S Putative inner membrane protein (DUF1819)
AIIGCJOP_01674 5.7e-85 S Domain of unknown function (DUF1788)
AIIGCJOP_01675 0.0 L DNA recombination
AIIGCJOP_01676 0.0 V COG1002 Type II restriction enzyme, methylase subunits
AIIGCJOP_01677 7.3e-102 S AAA domain, putative AbiEii toxin, Type IV TA system
AIIGCJOP_01678 4.2e-37
AIIGCJOP_01679 0.0 S PglZ domain
AIIGCJOP_01680 0.0 3.4.21.53 O ATP-dependent Lon-type protease
AIIGCJOP_01683 3.5e-146 hdfR K Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon
AIIGCJOP_01684 5.4e-48 yifE S Protein of unknown function, DUF
AIIGCJOP_01685 8.3e-258 comM O ATPase with chaperone activity
AIIGCJOP_01686 1.3e-309 ilvG 2.2.1.6 H acetolactate synthase
AIIGCJOP_01687 4.7e-39 ilvM 2.2.1.6 S acetolactate synthase
AIIGCJOP_01688 3.4e-177 ilvE 2.6.1.21, 2.6.1.42 E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AIIGCJOP_01689 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
AIIGCJOP_01690 8.9e-292 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AIIGCJOP_01691 3.7e-165 ilvY K transcriptional regulator
AIIGCJOP_01692 2e-280 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AIIGCJOP_01693 4.9e-47 ppiC 5.2.1.8 O PPIC-type PPIASE domain
AIIGCJOP_01694 6.7e-44 ppiC 5.2.1.8 G PPIC-type PPIASE domain
AIIGCJOP_01695 0.0 rep 3.6.4.12 L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
AIIGCJOP_01696 6.4e-263 gppA 3.6.1.11, 3.6.1.40 FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities
AIIGCJOP_01697 1.1e-239 rhlB 3.6.4.13 JKL DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA
AIIGCJOP_01698 4.7e-57 trxA O Belongs to the thioredoxin family
AIIGCJOP_01699 8.2e-235 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AIIGCJOP_01700 5.8e-184 wecA 2.7.8.33, 2.7.8.35, 5.1.3.14 M Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55)
AIIGCJOP_01701 5.4e-192 wzzE M Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AIIGCJOP_01702 1.5e-200 wecB 5.1.3.14 M Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues
AIIGCJOP_01703 4.8e-235 wecC 1.1.1.336 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AIIGCJOP_01704 2.3e-111 wecD 2.3.1.210 K Catalyzes the acetylation of dTDP-fucosamine (dTDP-4- amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA)
AIIGCJOP_01705 1.2e-200 wecE 2.6.1.59 E Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate
AIIGCJOP_01706 1.5e-217 wzxE U Mediates the transbilayer movement of Und-PP-GlcNAc- ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA)
AIIGCJOP_01707 7.8e-202 rffT 2.4.1.325 GT56 CG Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis
AIIGCJOP_01708 2.1e-244 wzyE S Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units
AIIGCJOP_01709 7.9e-129 rffM 2.4.1.180, 2.4.1.187 GT26 M Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis
AIIGCJOP_01710 1.6e-247 yifK E 'involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine'
AIIGCJOP_01714 1.7e-07
AIIGCJOP_01715 9.4e-180 S Protein involved in biological_process
AIIGCJOP_01716 4.7e-216 hemY H enzyme of heme biosynthesis
AIIGCJOP_01717 2.1e-160 hemX 2.1.1.107, 4.2.1.75 H HemX, putative uroporphyrinogen-III C-methyltransferase
AIIGCJOP_01718 1.9e-122 hemD 2.1.1.107, 2.5.1.61, 4.2.1.75 H Uroporphyrinogen-III synthase
AIIGCJOP_01719 1.5e-144 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
AIIGCJOP_01720 0.0 cyaA 4.6.1.1 F Adenylate cyclase
AIIGCJOP_01721 6.6e-56 cyaY 1.16.3.1 P Belongs to the frataxin family
AIIGCJOP_01722 7e-27 yifL N Prokaryotic lipoprotein-attachment site
AIIGCJOP_01723 8.5e-156 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AIIGCJOP_01724 9e-122 yigA S protein conserved in bacteria
AIIGCJOP_01725 1.3e-165 xerC D Belongs to the 'phage' integrase family. XerC subfamily
AIIGCJOP_01726 2.7e-126 yigB 3.1.3.10, 3.1.3.102, 3.1.3.104 S Hydrolase
AIIGCJOP_01727 0.0 uvrD 3.6.4.12 L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
AIIGCJOP_01728 6.1e-174 corA P Mediates influx of magnesium ions
AIIGCJOP_01729 2.6e-158 rarD S TIGRFAM RarD protein
AIIGCJOP_01730 1.6e-79 yigI Q Thioesterase-like superfamily
AIIGCJOP_01731 8e-157 pldA 3.1.1.32, 3.1.1.4 M Phospholipase
AIIGCJOP_01732 0.0 recQ 3.6.4.12 L DNA helicase
AIIGCJOP_01733 7.9e-106 rhtC E threonine efflux protein
AIIGCJOP_01734 8.7e-105 rhtB E efflux protein
AIIGCJOP_01735 4.7e-193 pldB 3.1.1.5 I PFAM Alpha beta hydrolase
AIIGCJOP_01736 1.9e-152 yigL S Hydrolase
AIIGCJOP_01737 4.6e-163 yigM EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AIIGCJOP_01738 8.5e-176 metR K transcriptional regulator
AIIGCJOP_01739 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AIIGCJOP_01740 4.1e-32
AIIGCJOP_01741 2.5e-35 S Protein of unknown function (DUF2778)
AIIGCJOP_01742 4.6e-52 S Type VI secretion system effector
AIIGCJOP_01743 1.2e-148 ysgA 3.1.1.45 Q Dienelactone hydrolase
AIIGCJOP_01744 2e-135 udp 2.4.2.3 F Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AIIGCJOP_01745 1.9e-219 rmuC V DNA Recombination protein RmuC
AIIGCJOP_01746 7e-141 ubiE 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)
AIIGCJOP_01747 2.9e-105 yigP S protein conserved in bacteria
AIIGCJOP_01748 0.0 ubiB S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AIIGCJOP_01749 7.4e-34 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
AIIGCJOP_01750 4.4e-65 tatB U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation
AIIGCJOP_01751 1e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides
AIIGCJOP_01752 5.6e-141 tatD L 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair
AIIGCJOP_01753 4.7e-85 rfaH K Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho- dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains
AIIGCJOP_01754 2.7e-293 ubiD 4.1.1.61, 4.1.1.98 H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis
AIIGCJOP_01755 4.4e-129 fre 1.16.1.3, 1.17.1.1, 1.5.1.41 C COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
AIIGCJOP_01756 2.7e-216 fadA 2.3.1.16 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
AIIGCJOP_01757 0.0 fadB 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate
AIIGCJOP_01758 8.3e-262 pepQ 3.4.11.9, 3.4.13.9 E Splits dipeptides with a prolyl residue in the C- terminal position
AIIGCJOP_01759 3e-105 yigZ 2.1.1.45, 3.4.13.9 S YigZ family
AIIGCJOP_01760 1.2e-269 trkH P Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AIIGCJOP_01761 4.2e-95 hemG 1.3.5.3 CH Protoporphyrinogen oxidase
AIIGCJOP_01762 1.8e-187 murB 1.3.1.98 M cell wall formation
AIIGCJOP_01763 1.6e-169 birA 2.7.1.33, 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AIIGCJOP_01764 0.0 yhjK T the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation
AIIGCJOP_01765 2.7e-225 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AIIGCJOP_01766 6.8e-262 yhjJ S Peptidase, M16
AIIGCJOP_01767 1.5e-161 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
AIIGCJOP_01768 1.2e-135 yhjH 3.1.4.52 T In Escherichia coli this protein is involved in flagellar function
AIIGCJOP_01769 0.0 yhjG M protein involved in outer membrane biogenesis
AIIGCJOP_01770 5.9e-236 yhjE EGP Major facilitator superfamily
AIIGCJOP_01771 6.7e-182 yhjD S Membrane
AIIGCJOP_01772 1.5e-161 yhjC K transcriptional regulator
AIIGCJOP_01773 1e-123 IQ short-chain dehydrogenase
AIIGCJOP_01774 1.6e-91 J Acetyltransferases, including N-acetylases of ribosomal proteins
AIIGCJOP_01775 6e-259
AIIGCJOP_01776 0.0 treF 3.2.1.28 GH37 G Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AIIGCJOP_01777 4.1e-08 S Domain of unknown function (DUF4762)
AIIGCJOP_01778 1.1e-68 dsbA_1 O Thiol disulfide interchange protein
AIIGCJOP_01779 5.1e-96 htrB 2.3.1.241 M (ABC) transporter
AIIGCJOP_01780 2.2e-272 lagD V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AIIGCJOP_01781 1.6e-118 macA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AIIGCJOP_01782 1.4e-278 macB V Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides
AIIGCJOP_01783 3e-145 cusC MU outer_NodT efflux transporter, outer membrane factor (OMF) lipo, NodT family protein
AIIGCJOP_01784 8.6e-192 fabF_1 2.3.1.179 IQ Belongs to the beta-ketoacyl-ACP synthases family
AIIGCJOP_01785 1.3e-52 I MaoC like domain
AIIGCJOP_01786 2.6e-23 IQ acyl carrier protein
AIIGCJOP_01787 4.5e-84 IQ 3-oxoacyl- acyl-carrier protein reductase
AIIGCJOP_01788 1.9e-09
AIIGCJOP_01789 6.1e-52
AIIGCJOP_01790 1.6e-77 cre L Phage integrase family
AIIGCJOP_01793 2.7e-168 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AIIGCJOP_01795 1.4e-33 yegD O StbA protein
AIIGCJOP_01799 4.9e-42 K Helix-turn-helix XRE-family like proteins
AIIGCJOP_01800 1.9e-27 DJ Addiction module toxin, RelE StbE family
AIIGCJOP_01802 6.5e-20
AIIGCJOP_01808 3e-31 S VRR-NUC domain
AIIGCJOP_01809 4.6e-28
AIIGCJOP_01810 3.1e-18
AIIGCJOP_01811 1.3e-43 higA K transcriptional regulator
AIIGCJOP_01812 1.5e-18 higB S HigB_toxin, RelE-like toxic component of a toxin-antitoxin system
AIIGCJOP_01813 2.5e-43 L Transposase and inactivated derivatives
AIIGCJOP_01816 2.2e-100 parA D Cobyrinic acid a,c-diamide synthase
AIIGCJOP_01817 2.7e-22 S ParG
AIIGCJOP_01818 1.4e-156 S RePlication protein
AIIGCJOP_01819 2.2e-105 L Phage integrase family protein
AIIGCJOP_01821 6.1e-48 L IS1 transposase
AIIGCJOP_01822 2.6e-45 L transposition, DNA-mediated
AIIGCJOP_01826 3.6e-15
AIIGCJOP_01828 4.8e-46 G 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process
AIIGCJOP_01829 7.3e-186 ISPlu13C L Transposase
AIIGCJOP_01830 3.3e-110 E LysE type translocator
AIIGCJOP_01831 1.6e-98 arcR T Winged helix-turn-helix DNA binding
AIIGCJOP_01832 1.2e-146 amiD 3.5.1.28 V N-acetylmuramoyl-L-alanine amidase
AIIGCJOP_01833 1.9e-50 ybjQ S Belongs to the UPF0145 family
AIIGCJOP_01834 3.1e-87 ybjP M Induced during stationary phase and by acivicin (a glutamine analog)
AIIGCJOP_01835 3.2e-130 artP E Arginine ABC transporter, ATP-binding protein
AIIGCJOP_01836 4.4e-132 artI ET belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_01837 2.5e-124 artQ P arginine transporter permease subunit ArtQ
AIIGCJOP_01838 9.4e-105 artM P (ABC) transporter
AIIGCJOP_01839 3.6e-134 artJ ET belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_01840 6.5e-252 T PhoQ Sensor
AIIGCJOP_01841 2.4e-119 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_01842 5.5e-206 rumB 2.1.1.189, 2.1.1.190 J Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA
AIIGCJOP_01843 1.5e-80 ybjO S Membrane
AIIGCJOP_01844 2.8e-146 potI P ABC-type spermidine putrescine transport system, permease component II
AIIGCJOP_01845 4.8e-171 potH P ABC-type spermidine putrescine transport system, permease component I
AIIGCJOP_01846 1.3e-207 potG P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AIIGCJOP_01847 2.1e-210 potF P Required for the activity of the bacterial periplasmic transport system of putrescine
AIIGCJOP_01848 1.3e-79 ybjN S sensory transduction regulator
AIIGCJOP_01849 4.3e-161 rimK 6.3.1.17, 6.3.2.32, 6.3.2.41 F Belongs to the RimK family
AIIGCJOP_01850 7.5e-132 nfsA 1.5.1.38, 1.5.1.39 C Nitroreductase
AIIGCJOP_01851 4.1e-43 grxA 1.17.4.1 O Glutaredoxin
AIIGCJOP_01852 1.2e-43 ybjM S Putative inner membrane protein of Enterobacteriaceae
AIIGCJOP_01853 7e-311 ybjL P transport protein
AIIGCJOP_01854 6.4e-88 crtZ 1.14.15.24 I Fatty acid hydroxylase superfamily
AIIGCJOP_01855 2.3e-157 crtB 2.5.1.32, 2.5.1.99 I Phytoene squalene synthetase
AIIGCJOP_01856 1.6e-282 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q COG1233 Phytoene dehydrogenase and related proteins
AIIGCJOP_01857 2e-190 crtL 5.5.1.19 CH lycopene cyclase
AIIGCJOP_01858 1.4e-171 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AIIGCJOP_01859 6.5e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AIIGCJOP_01860 3.9e-83 S Uncharacterized protein conserved in bacteria (DUF2239)
AIIGCJOP_01861 6.1e-94 ybjK K transcriptional regulator
AIIGCJOP_01862 4.1e-207 ybjJ G Major facilitator superfamily
AIIGCJOP_01863 6.8e-142 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 C Hydrolase
AIIGCJOP_01864 2.3e-218 mdfA EGP multi-drug
AIIGCJOP_01865 8.4e-107 S PAP2 superfamily
AIIGCJOP_01866 5.4e-105 ybjG 3.6.1.27 I Phosphatase
AIIGCJOP_01867 2.8e-137 deoR K transcriptional
AIIGCJOP_01868 1.5e-222 dacC 3.4.16.4 M Belongs to the peptidase S11 family
AIIGCJOP_01869 1.8e-110 yliJ 2.5.1.18 O Glutathione S-Transferase
AIIGCJOP_01870 3e-204 yliI G glucose sorbosone
AIIGCJOP_01871 4.7e-193 mdoB 2.7.8.20 M PFAM Sulfatase
AIIGCJOP_01872 1.1e-65 bssR S Biofilm formation protein (YliH/bssR)
AIIGCJOP_01873 1.9e-258 rimO 2.8.4.4 J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
AIIGCJOP_01874 1.9e-186 agaS M Glucosamine--fructose-6-phosphate aminotransferase
AIIGCJOP_01875 8.3e-180 M glucosamine--fructose-6-phosphate aminotransferase
AIIGCJOP_01876 4.9e-151 G PTS mannose transporter subunit IID
AIIGCJOP_01877 2.7e-111 G PTS system
AIIGCJOP_01878 4.8e-79 2.7.1.191 G PTS system sorbose subfamily IIB component
AIIGCJOP_01879 2.8e-62 G PTS sugar transporter
AIIGCJOP_01880 0.0 K transcriptional regulator
AIIGCJOP_01881 8.9e-48
AIIGCJOP_01882 1.2e-11
AIIGCJOP_01883 3.1e-72 K Acetyltransferase
AIIGCJOP_01884 2.7e-115 3.5.1.124 F intracellular protease amidase
AIIGCJOP_01885 1.3e-134 nfrA2 1.5.1.39 C nitroreductase
AIIGCJOP_01886 1.4e-148 gsiD P transport
AIIGCJOP_01887 8e-163 gsiC P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AIIGCJOP_01888 9.8e-291 gsiB E Extracellular solute-binding protein, family 5
AIIGCJOP_01889 0.0 gsiA P ATPase activity
AIIGCJOP_01890 6.7e-165 iaaA 3.4.19.5, 3.5.1.1 E asparaginase
AIIGCJOP_01891 1.2e-225 moeA 2.10.1.1 H molybdopterin
AIIGCJOP_01892 1.2e-127 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AIIGCJOP_01893 1.2e-107 tal 2.2.1.2 H Belongs to the transaldolase family. Type
AIIGCJOP_01894 3.6e-168 ybiY 1.97.1.4 O Pyruvate formate lyase-activating protein
AIIGCJOP_01895 0.0 ybiW 2.3.1.54 C Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde
AIIGCJOP_01896 1.2e-146 supH 3.1.3.102, 3.1.3.104, 3.1.3.23 C Hydrolase
AIIGCJOP_01897 8.4e-248 ybiU S Protein of unknown function (DUF1479)
AIIGCJOP_01898 8.1e-296 ybiT S ABC transporter
AIIGCJOP_01899 1.4e-172 ybiS M ErfK YbiS YcfS YnhG family protein
AIIGCJOP_01900 1.9e-278 nodT M RND efflux system, outer membrane lipoprotein
AIIGCJOP_01901 1.2e-288 emrb1 EGP Major facilitator Superfamily
AIIGCJOP_01902 2.7e-77 emrK V multidrug resistance
AIIGCJOP_01903 4.1e-190 ybiR P Citrate transporter
AIIGCJOP_01904 1.3e-79 mntR K transcriptional regulator
AIIGCJOP_01905 5.8e-16
AIIGCJOP_01906 2.5e-297 ybiP 2.7.8.42, 2.7.8.43 S membrane-associated metal-dependent hydrolase
AIIGCJOP_01907 2.2e-85 ompX M PFAM virulence-related outer membrane protein
AIIGCJOP_01908 1.7e-146 rhtA S EamA-like transporter family
AIIGCJOP_01909 1.5e-86 dps P During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
AIIGCJOP_01910 7e-133 glnH ET belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_01911 7.8e-112 glnP P (ABC) transporter
AIIGCJOP_01912 1e-128 glnQ E (ABC) transporter
AIIGCJOP_01913 0.0 ybiO M mechanosensitive ion channel
AIIGCJOP_01914 3.1e-167 rlmF 2.1.1.181 J Specifically methylates the adenine in position 1618 of 23S rRNA
AIIGCJOP_01915 2.1e-36 mcbA S colanic acid metabolic process
AIIGCJOP_01916 0.0 fiu P receptor
AIIGCJOP_01917 2.1e-120 ybiX S PkhD-type hydroxylase
AIIGCJOP_01918 1.7e-41 ybiI T DnaK suppressor protein
AIIGCJOP_01920 7.8e-169 ybiB 2.4.2.18 E Glycosyl transferase
AIIGCJOP_01921 2.1e-62 NU Fimbrial protein
AIIGCJOP_01922 8.1e-88 M PFAM pili assembly chaperone
AIIGCJOP_01923 0.0 NU COG3188 P pilus assembly protein, porin PapC
AIIGCJOP_01924 1.6e-84 NU Fimbrial protein
AIIGCJOP_01925 1.1e-57 NU Fimbrial protein
AIIGCJOP_01926 0.0 dinG 3.6.4.12 KL helicase
AIIGCJOP_01927 3.5e-215 rhlE 3.6.4.13 JKL DEAD-box RNA helicase involved in
AIIGCJOP_01928 7e-116 ybiH K Transcriptional regulator
AIIGCJOP_01929 3.3e-130 ybhG M PFAM secretion protein HlyD
AIIGCJOP_01930 0.0 ybhF V (ABC) transporter
AIIGCJOP_01931 3.7e-194 ybhS V ABC-type multidrug transport system, permease component
AIIGCJOP_01932 1.2e-197 ybhR V Transport Permease Protein
AIIGCJOP_01933 4.5e-65 ybhQ S inner membrane protein YbhQ
AIIGCJOP_01934 5.8e-143 ybhP L Endonuclease Exonuclease Phosphatase
AIIGCJOP_01935 2.8e-235 clsB 2.7.8.8 I Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AIIGCJOP_01936 9.5e-167 mprF 2.3.2.3 S Membrane
AIIGCJOP_01937 2.4e-119 ybhL S Belongs to the BI1 family
AIIGCJOP_01938 1.3e-78 moaE 2.8.1.12 H Molybdopterin converting factor, large subunit
AIIGCJOP_01939 1.9e-31 moaD 2.7.7.77, 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AIIGCJOP_01940 2.4e-81 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
AIIGCJOP_01941 4.5e-91 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
AIIGCJOP_01942 1.9e-186 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AIIGCJOP_01943 1.4e-156 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AIIGCJOP_01944 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AIIGCJOP_01945 1.1e-114 urtE E ABC transporter ATP-binding protein
AIIGCJOP_01946 1.1e-114 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AIIGCJOP_01947 1.7e-118 bioC 2.1.1.197 H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
AIIGCJOP_01948 6.7e-191 bioF 2.3.1.47, 2.8.1.6 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
AIIGCJOP_01949 2.6e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AIIGCJOP_01950 1.5e-250 bioA 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
AIIGCJOP_01951 7e-86 ybhB S PFAM PEBP family protein
AIIGCJOP_01952 1.7e-271 hutH 3.5.2.7, 4.3.1.3 E histidine ammonia-lyase
AIIGCJOP_01953 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AIIGCJOP_01954 3.5e-129 hutC K histidine utilization repressor
AIIGCJOP_01955 3.5e-158 hutG 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
AIIGCJOP_01956 1.2e-217 hutI 3.5.2.7 Q 'catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway'
AIIGCJOP_01957 1.2e-238 ybhC 3.1.1.11, 4.2.2.2 G Pectinesterase
AIIGCJOP_01959 1.5e-191 pgl 3.1.1.31 G Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
AIIGCJOP_01960 3.1e-142 ybhA S hydrolases of the HAD superfamily
AIIGCJOP_01961 6.3e-196 modC 3.6.3.29 P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AIIGCJOP_01962 2.7e-115 modB 3.6.3.29 P PFAM binding-protein-dependent transport systems inner membrane component
AIIGCJOP_01963 8e-124 modA P TIGRFAM molybdenum ABC transporter, periplasmic
AIIGCJOP_01964 5.3e-16 acrZ U drug transmembrane transporter activity
AIIGCJOP_01965 1.2e-130 modE H Transcriptional regulator
AIIGCJOP_01966 2e-264 modF 3.6.3.21, 3.6.3.34 P ABC-type molybdenum transport system ATPase component photorepair protein PhrA
AIIGCJOP_01967 7.1e-197 galE 5.1.3.2 M udp-glucose 4-epimerase
AIIGCJOP_01968 1.4e-203 galT 2.7.7.12 H galactose-1-phosphate uridylyltransferase
AIIGCJOP_01969 2.9e-210 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AIIGCJOP_01970 1.7e-193 galM 2.7.1.6, 5.1.3.3 G converts alpha-aldose to the beta-anomer
AIIGCJOP_01971 1.5e-143 gpmA 5.4.2.11 G Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily
AIIGCJOP_01972 2.7e-199 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AIIGCJOP_01973 2.9e-08 ybgS S YbgS-like protein
AIIGCJOP_01974 2.1e-166 zitB P cation diffusion facilitator family transporter
AIIGCJOP_01975 3.6e-126 pnuC H nicotinamide mononucleotide transporter
AIIGCJOP_01976 2e-194 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AIIGCJOP_01982 5.5e-80 cpoB 3.5.1.28 D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AIIGCJOP_01983 1.4e-60 pal M Belongs to the ompA family
AIIGCJOP_01984 3.6e-153 tolB U involved in the tonB-independent uptake of proteins
AIIGCJOP_01985 1.7e-49 tolA M Required for outer membrane integrity, uptake of group A colicins, role in translocation of filamenous phage DNA to cytoplasm, role in surface expression of O-antigen
AIIGCJOP_01986 7e-69 tolR U biopolymer transport protein
AIIGCJOP_01987 1.3e-117 tolQ U PFAM MotA TolQ ExbB proton channel
AIIGCJOP_01988 2.8e-67 ybgC S Acyl-CoA thioesterase
AIIGCJOP_01989 3e-44 ybgE S cyd operon protein YbgE
AIIGCJOP_01990 3.5e-12 ybgT 1.10.3.14 S oxidoreductase activity, acting on diphenols and related substances as donors
AIIGCJOP_01991 3.8e-207 cydB 1.10.3.14 C cytochrome d ubiquinol oxidase, subunit
AIIGCJOP_01992 4e-287 cydA 1.10.3.14 C oxidase, subunit
AIIGCJOP_01993 4.6e-160 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AIIGCJOP_01994 3.5e-216 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
AIIGCJOP_01995 1.6e-203 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
AIIGCJOP_01996 0.0 sucA 1.2.4.2, 4.1.1.71 C Dehydrogenase E1 component
AIIGCJOP_01997 5.3e-138 sdhB 1.3.5.1, 1.3.5.4 C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AIIGCJOP_01998 0.0 sdhA 1.3.5.1, 1.3.5.4 C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily
AIIGCJOP_01999 5.7e-29 sdhD C Membrane-anchoring subunit of succinate dehydrogenase (SDH)
AIIGCJOP_02000 1.9e-83 sdhC C succinate dehydrogenase
AIIGCJOP_02001 5e-248 gltA 2.3.3.1 C Belongs to the citrate synthase family
AIIGCJOP_02002 1.5e-138 nei 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates
AIIGCJOP_02003 2.1e-109 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AIIGCJOP_02004 2.3e-176 S Membrane
AIIGCJOP_02005 1.6e-123 S Membrane
AIIGCJOP_02006 2.3e-128 ybgL E Belongs to the UPF0271 (lamB) family
AIIGCJOP_02007 6.6e-173 ybgK 3.5.1.54, 6.3.4.6 E Allophanate hydrolase subunit 2
AIIGCJOP_02008 2.9e-114 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
AIIGCJOP_02009 2.1e-137 ybgI 3.5.4.16 S metal-binding protein
AIIGCJOP_02010 1.6e-263 phrB 4.1.99.3 L Belongs to the DNA photolyase family
AIIGCJOP_02011 9.7e-32 ybfA S Membrane
AIIGCJOP_02012 1e-296 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AIIGCJOP_02013 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AIIGCJOP_02014 2e-87 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AIIGCJOP_02015 0.0 T PhoQ Sensor
AIIGCJOP_02016 3.3e-121 K response regulator
AIIGCJOP_02017 1.6e-310 pgm 5.4.2.2 G Phosphoglucomutase
AIIGCJOP_02018 2e-89 seqA L Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AIIGCJOP_02019 1.4e-139 ybfF S Alpha beta hydrolase
AIIGCJOP_02020 1.7e-42 ybfE S CopG domain protein DNA-binding domain protein
AIIGCJOP_02021 4.7e-99 fldA C Low-potential electron donor to a number of redox enzymes
AIIGCJOP_02022 1.5e-82 fur K Belongs to the Fur family
AIIGCJOP_02023 6.9e-48 ybfN S YbfN-like lipoprotein
AIIGCJOP_02024 1.2e-274 chiP S Outer membrane porin
AIIGCJOP_02025 0.0 glnS 6.1.1.18 J Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AIIGCJOP_02026 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Phosphotransferase System
AIIGCJOP_02027 1.1e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AIIGCJOP_02028 7e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AIIGCJOP_02029 7.4e-225 nagC 2.1.1.303 K Regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon
AIIGCJOP_02030 1.9e-138 nagD G HAD-superfamily hydrolase, subfamily IIA
AIIGCJOP_02031 0.0 asnB 6.3.5.4 E Asparagine synthase, glutamine-hydrolyzing
AIIGCJOP_02033 1.3e-08
AIIGCJOP_02034 1.7e-07
AIIGCJOP_02035 1.7e-07
AIIGCJOP_02039 4.7e-208 ubiF CH ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6
AIIGCJOP_02040 4.7e-271 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AIIGCJOP_02041 6.5e-185 ybeZ T phosphate starvation-inducible protein PhoH
AIIGCJOP_02042 9.2e-83 ybeY 2.6.99.2, 3.5.4.5 J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AIIGCJOP_02043 6e-160 corC P Mg2 and Co2 transporter CorC
AIIGCJOP_02044 1.6e-277 lnt GT2 M Transfers the fatty acyl group on membrane lipoproteins
AIIGCJOP_02045 3.1e-167 gltI ET ABC-type amino acid transport signal transduction systems periplasmic component domain
AIIGCJOP_02046 2.2e-126 gltJ P amino acid ABC transporter
AIIGCJOP_02047 6.8e-111 gltK P With GltJLPS and GadC for glutamate and GltJLP, DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate
AIIGCJOP_02048 2.6e-124 gltL 3.6.3.21 P Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for energy coupling to the transport system
AIIGCJOP_02049 1.3e-163 rihA G Belongs to the IUNH family
AIIGCJOP_02050 3.1e-81 ybeL 1.17.4.1, 4.6.1.1 J Zinc-ribbon containing domain
AIIGCJOP_02051 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AIIGCJOP_02052 3.4e-95 lptE M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AIIGCJOP_02053 1.1e-184 holA 2.7.7.7 L dna polymerase III delta subunit
AIIGCJOP_02054 7e-113 nadD 2.7.7.18, 3.5.4.4, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AIIGCJOP_02055 1.3e-51 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AIIGCJOP_02056 2e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AIIGCJOP_02057 0.0 mrdA 3.4.16.4 M Catalyzes cross-linking of the peptidoglycan cell wall
AIIGCJOP_02058 3.2e-198 mrdB M Peptidoglycan polymerase that is essential for cell wall elongation
AIIGCJOP_02059 1.2e-176 rlpA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AIIGCJOP_02060 2.2e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AIIGCJOP_02061 3.8e-41 ybeD S Protein of unknown function (DUF493)
AIIGCJOP_02062 1e-116 lipB 2.3.1.181 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
AIIGCJOP_02063 4.5e-153 ybeF K transcriptional regulator
AIIGCJOP_02064 1.7e-184 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AIIGCJOP_02065 2.5e-24 tatE U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA
AIIGCJOP_02066 4.5e-130 ybeM 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AIIGCJOP_02067 1.9e-62 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AIIGCJOP_02068 4.3e-32 cspE K SMART Cold shock protein
AIIGCJOP_02069 1.8e-46 pagP 2.3.1.251 M Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors
AIIGCJOP_02070 1.4e-232 dcuC C C4-dicarboxylate
AIIGCJOP_02071 4.1e-147 rna 3.1.27.1, 3.1.27.6 J Belongs to the RNase T2 family
AIIGCJOP_02072 7.4e-112 IV02_24660 S Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family
AIIGCJOP_02073 6.2e-67 rnk K regulator of nucleoside diphosphate kinase
AIIGCJOP_02074 5.2e-234 ybdR 1.1.1.14 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
AIIGCJOP_02075 1.1e-66 uspG T Belongs to the universal stress protein A family
AIIGCJOP_02076 9e-292 ahpF O alkyl hydroperoxide reductase
AIIGCJOP_02077 3.9e-104 ahpC 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AIIGCJOP_02079 1.2e-115 ybdO K LysR substrate binding domain
AIIGCJOP_02080 2.8e-213 ybdL 2.6.1.17, 2.6.1.88 E aminotransferase
AIIGCJOP_02081 2.6e-109 mtnB 3.1.3.87, 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
AIIGCJOP_02082 7.4e-121 mtnC 3.1.3.77 E Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AIIGCJOP_02083 6.3e-99 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AIIGCJOP_02084 4.3e-173 mtnA 4.2.1.109, 5.3.1.23 J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AIIGCJOP_02085 6e-222 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AIIGCJOP_02086 1.3e-245 S LVIVD repeat
AIIGCJOP_02087 5.9e-194 G Sugar ABC Transporter
AIIGCJOP_02088 2.4e-165 rbsC_3 G Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_02089 3.1e-273 mglA_3 3.6.3.17 G (ABC) transporter
AIIGCJOP_02090 2.2e-188 gldA 1.1.1.1, 1.1.1.6 C Iron-containing alcohol dehydrogenase
AIIGCJOP_02091 4e-120 IQ KR domain
AIIGCJOP_02092 6.8e-31 relE DJ nuclease activity
AIIGCJOP_02093 2.5e-60 K transcriptional regulator
AIIGCJOP_02094 1.8e-32 ybdD S Pfam:DUF466
AIIGCJOP_02095 0.0 cstA T Carbon starvation protein
AIIGCJOP_02096 1.3e-23 J SmpA / OmlA family
AIIGCJOP_02097 6.5e-61
AIIGCJOP_02098 4.2e-71 entH 3.1.2.28 Q Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules
AIIGCJOP_02099 6.1e-121 IQ involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin
AIIGCJOP_02100 3.7e-162 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase
AIIGCJOP_02101 5.4e-292 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
AIIGCJOP_02102 2.8e-205 entC 5.4.4.2 HQ Isochorismate synthase
AIIGCJOP_02103 4.3e-159 fepB P Periplasmic binding protein
AIIGCJOP_02104 3.4e-209 entS EGP Exports the siderophore enterobactin out of the cell
AIIGCJOP_02105 1.4e-160 fepD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AIIGCJOP_02106 1.5e-154 fepG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AIIGCJOP_02107 8.2e-140 fepC 3.6.3.34 HP (ABC) transporter
AIIGCJOP_02108 1.2e-195
AIIGCJOP_02109 5.5e-16 L Resolvase
AIIGCJOP_02110 0.0 entF 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
AIIGCJOP_02111 3.4e-32 ybdZ P PFAM MbtH domain protein
AIIGCJOP_02112 9e-215 fes P esterase
AIIGCJOP_02113 0.0 fepA P Receptor
AIIGCJOP_02115 0.0 fdhF 1.17.1.10, 1.17.1.9, 1.17.99.7 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_02116 1.2e-73 fdhF 1.17.1.10, 1.17.1.9, 1.17.99.7 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_02117 1.1e-181 hoxN S rRNA processing
AIIGCJOP_02118 0.0 hypF O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AIIGCJOP_02119 0.0 fdhF 1.17.1.10, 1.17.1.9, 1.17.99.7 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_02120 5.1e-101 hydN C electron transport
AIIGCJOP_02121 3.8e-84 S Type VI secretion system effector
AIIGCJOP_02122 5.5e-76 S Protein involved in biological_process
AIIGCJOP_02123 1.8e-265 iphP 3.1.3.48 T Tyrosine phosphatase family
AIIGCJOP_02124 1.1e-53
AIIGCJOP_02125 2.4e-14 S Domain of unknown function (DUF4440)
AIIGCJOP_02126 6e-125 S Dienelactone hydrolase
AIIGCJOP_02127 6.5e-105 K transcriptional regulator
AIIGCJOP_02128 1.2e-69 E LysE type translocator
AIIGCJOP_02129 1.9e-49 tolA M TolA C-terminal
AIIGCJOP_02130 1e-35 S Protein of unknown function (DUF1493)
AIIGCJOP_02131 4.1e-78 S Type VI secretion system effector
AIIGCJOP_02132 3.8e-81 hycI 3.4.23.51 C hydrogenase 3 maturation protease
AIIGCJOP_02133 8.2e-67 hycH E Formate hydrogen-lyase
AIIGCJOP_02134 3.3e-130 hyfI C NADH ubiquinone oxidoreductase, 20
AIIGCJOP_02135 2.8e-83 hycF C the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3
AIIGCJOP_02136 0.0 hycE C HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide
AIIGCJOP_02137 3.7e-152 hycD C HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide
AIIGCJOP_02138 4e-299 hycC CP formate hydrogenlyase subunit 3
AIIGCJOP_02139 1.6e-106 hycB C Formate hydrogenlyase
AIIGCJOP_02140 1.7e-68 hycA E seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon
AIIGCJOP_02141 1.3e-57 hypA S Probably plays a role in a hydrogenase nickel cofactor insertion step
AIIGCJOP_02142 1.1e-142 hypB KO Hydrogenase accessory protein HypB
AIIGCJOP_02143 1.2e-40 hypC O Hydrogenase assembly chaperone hypC hupF
AIIGCJOP_02144 3.8e-199 hypD O Belongs to the HypD family
AIIGCJOP_02145 5.7e-170 hypE O hydrogenase expression formation protein HypE
AIIGCJOP_02146 0.0 fhlA KT transcriptional regulator
AIIGCJOP_02147 3.8e-95 entD 6.3.2.14 Q Belongs to the P-Pant transferase superfamily
AIIGCJOP_02148 2.6e-169 rbsB_1 G Periplasmic binding protein LacI transcriptional regulator
AIIGCJOP_02149 3.4e-101 S Lipoprotein
AIIGCJOP_02150 8.9e-276 rbsA_1 3.6.3.17 P import. Responsible for energy coupling to the transport system
AIIGCJOP_02151 7.4e-184 G Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_02152 1.7e-168 deoR_1 K transcriptional regulator
AIIGCJOP_02153 3.9e-63 S Type VI secretion system effector, Hcp
AIIGCJOP_02154 3.6e-07
AIIGCJOP_02155 7e-58
AIIGCJOP_02156 9.4e-155 tktB 2.2.1.1 G Transketolase
AIIGCJOP_02157 5.3e-170 tktA 2.2.1.1 G Transketolase
AIIGCJOP_02158 1e-270 G L-fucose isomerase
AIIGCJOP_02159 9.6e-267 glpK3 2.7.1.30 G Belongs to the FGGY kinase family
AIIGCJOP_02160 3.2e-90 csy4 S crispr-associated protein, csy4
AIIGCJOP_02161 1.5e-178 csy3 S crispr-associated protein
AIIGCJOP_02162 7e-167 csy2 S crispr-associated protein
AIIGCJOP_02163 9.2e-213 csy1 S crispr-associated protein
AIIGCJOP_02164 0.0 cas3 L CRISPR-associated helicase, Cas3
AIIGCJOP_02165 4.6e-169 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AIIGCJOP_02166 6e-15 hokE S Hok/gef family
AIIGCJOP_02167 1.5e-11
AIIGCJOP_02169 2.7e-126 rimL J Acetyltransferases including N-acetylases of ribosomal proteins
AIIGCJOP_02170 1.4e-78 csp K Cold-Shock Protein
AIIGCJOP_02171 5.4e-34 ymjA S Protein of unknown function (DUF2543)
AIIGCJOP_02172 7.9e-205 ybdK H ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AIIGCJOP_02173 0.0 ctpF P ATPase, P-type (transporting), HAD superfamily, subfamily IC
AIIGCJOP_02174 1.9e-08
AIIGCJOP_02175 5.8e-28 ybdJ S Protein of unknown function (DUF1158)
AIIGCJOP_02176 1.7e-57 ramA K Transcriptional regulator
AIIGCJOP_02177 3.6e-210 romA S Zn-dependent hydrolases of the beta-lactamase fold
AIIGCJOP_02178 8.6e-102 K transcriptional regulator
AIIGCJOP_02179 2.4e-65 ybdF S YjbR
AIIGCJOP_02180 2.1e-117 nfnB 1.5.1.34 C Nitroreductase
AIIGCJOP_02181 4.6e-40 K sequence-specific DNA binding
AIIGCJOP_02182 5.8e-47 S Phage-related protein
AIIGCJOP_02183 1.4e-164 K transcriptional
AIIGCJOP_02184 3e-249 EGP Major facilitator superfamily
AIIGCJOP_02185 1.2e-222 ybdG M Mechanosensitive Ion channel
AIIGCJOP_02186 4.8e-166 cytR 5.1.1.1 K Periplasmic binding protein LacI transcriptional regulator
AIIGCJOP_02187 7.5e-211 S oxidoreductase
AIIGCJOP_02188 7.5e-194 iolE G AP endonuclease
AIIGCJOP_02189 2.7e-214 yegT G Nucleoside H+ symporter
AIIGCJOP_02190 3.8e-52 S protein conserved in bacteria
AIIGCJOP_02191 2.3e-42 proV 3.6.3.32 K transcriptional regulator
AIIGCJOP_02192 1.2e-247 pheP E amino acid
AIIGCJOP_02193 0.0 S Phosphatase
AIIGCJOP_02194 0.0 fcuA P receptor
AIIGCJOP_02195 3.2e-187 S amine dehydrogenase activity
AIIGCJOP_02196 1.9e-86 VP1566
AIIGCJOP_02197 2.7e-63 yajD 2.1.1.148 L HNH endonuclease
AIIGCJOP_02199 9.8e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AIIGCJOP_02200 4.9e-31 yaaA S S4 domain
AIIGCJOP_02201 1.9e-275 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system
AIIGCJOP_02202 3.7e-177 K Protein involved in sequence-specific DNA binding transcription factor activity, DNA binding and regulation of transcription, DNA-templated
AIIGCJOP_02203 4.5e-94 ybcI S LexA-binding, inner membrane-associated putative hydrolase
AIIGCJOP_02204 1.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AIIGCJOP_02205 1.4e-89 ppiB 2.7.11.1, 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AIIGCJOP_02206 2.9e-128 lpxH 3.6.1.54 S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AIIGCJOP_02207 7.4e-24 S Protein of unknown function (DUF1471)
AIIGCJOP_02208 7.7e-20
AIIGCJOP_02209 5.7e-86 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AIIGCJOP_02210 4.5e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AIIGCJOP_02211 1.9e-187 selU H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AIIGCJOP_02212 3.1e-225 omp M Membrane
AIIGCJOP_02213 0.0 ybbP Q ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component
AIIGCJOP_02214 9.9e-118 ybbA Q (ABC) transporter
AIIGCJOP_02215 1.9e-101 tesA 3.1.1.5 E COG2755 Lysophospholipase L1 and related esterases
AIIGCJOP_02216 1.8e-139 ybbO S Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_02217 9.7e-147 ybbN O Thioredoxin
AIIGCJOP_02218 6.1e-133
AIIGCJOP_02219 7e-119 qmcA O COG0330 Membrane protease subunits stomatin prohibitin homologs
AIIGCJOP_02220 5.9e-74 ybbJ OU Membrane protein implicated in regulation of membrane protease activity
AIIGCJOP_02221 0.0 S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AIIGCJOP_02222 1.1e-119 S Protein of unknown function (DUF3142)
AIIGCJOP_02223 5.6e-68 cueR K Transcriptional regulator
AIIGCJOP_02224 0.0 copA 3.6.3.54 P P-type atpase
AIIGCJOP_02225 4.5e-138 ybaP S protein conserved in bacteria
AIIGCJOP_02226 9.8e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AIIGCJOP_02227 0.0 ushA 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
AIIGCJOP_02228 2.9e-213 fsr P fosmidomycin resistance protein
AIIGCJOP_02229 4.5e-281 ybaL P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AIIGCJOP_02230 1.5e-252 gsk 2.7.1.20, 2.7.1.73, 2.7.1.92 G COG0524 Sugar kinases, ribokinase family
AIIGCJOP_02231 6.6e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AIIGCJOP_02232 3.3e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AIIGCJOP_02233 0.0 htpG O Molecular chaperone. Has ATPase activity
AIIGCJOP_02234 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AIIGCJOP_02235 2.5e-42
AIIGCJOP_02236 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AIIGCJOP_02237 6e-97 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AIIGCJOP_02238 1e-60 ybaN S membrane
AIIGCJOP_02239 1.8e-79 priC L primosomal replication protein
AIIGCJOP_02240 3.7e-15 ybaM S cellular response to cell envelope stress
AIIGCJOP_02241 0.0 kefA M mechanosensitive ion channel
AIIGCJOP_02242 6.2e-49 acrR K transcriptional regulator
AIIGCJOP_02243 8.4e-197 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AIIGCJOP_02244 0.0 acrB V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AIIGCJOP_02245 1.3e-69 tomB S Biofilm formation regulator YbaJ
AIIGCJOP_02246 1.8e-33 hha S non-specific DNA-binding protein which affects the production of multiple proteins
AIIGCJOP_02247 3.4e-77 ylaC S Membrane
AIIGCJOP_02248 7e-18 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AIIGCJOP_02249 5.9e-259 ylaB 3.1.4.52 T signal transduction protein containing sensor and EAL
AIIGCJOP_02250 1.1e-59 ybaA S RNA signal recognition particle 4.5S RNA
AIIGCJOP_02251 0.0 lacZ 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
AIIGCJOP_02252 4.3e-176 lacI K binds specific sites in lac operon resulting in DNA looping between the operators
AIIGCJOP_02253 1.6e-98 S Membrane
AIIGCJOP_02254 3.8e-252 K Transcriptional regulator
AIIGCJOP_02255 2e-35
AIIGCJOP_02256 1e-35
AIIGCJOP_02257 5.8e-49 ybaZ 2.1.1.63 L PFAM Methylated-DNA- protein -cysteine S-methyltransferase
AIIGCJOP_02258 4.1e-93 ybaY S protein conserved in bacteria
AIIGCJOP_02259 1.2e-160 tesB I Acyl-CoA thioesterase
AIIGCJOP_02260 2.3e-208 amtB P Ammonium transporter
AIIGCJOP_02261 8.5e-54 glnK K Belongs to the P(II) protein family
AIIGCJOP_02262 0.0 mdlB V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
AIIGCJOP_02263 0.0 mdlA V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
AIIGCJOP_02264 3.6e-79 ybaO K transcriptional regulator
AIIGCJOP_02265 1.6e-199 cysK_2 2.5.1.47 E cysteine synthase
AIIGCJOP_02266 1.2e-154 cof S Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P)
AIIGCJOP_02267 0.0 ybaE S ABC transporter substrate-binding protein
AIIGCJOP_02268 3.9e-130 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AIIGCJOP_02269 1.3e-64 tesC S Thioesterase
AIIGCJOP_02270 1.5e-33 ybaV 3.1.26.11 L TIGRFAM competence protein ComEA helix-hairpin-helix
AIIGCJOP_02271 7.7e-298 ppiD 5.2.1.8 O peptidylprolyl isomerase
AIIGCJOP_02272 4.8e-39 hupB L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AIIGCJOP_02273 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AIIGCJOP_02274 4e-237 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AIIGCJOP_02275 1.6e-114 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AIIGCJOP_02276 1.1e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AIIGCJOP_02278 8.8e-53 bolA T Belongs to the BolA IbaG family
AIIGCJOP_02279 9e-96 yajG M lipoprotein
AIIGCJOP_02280 2.4e-254 ampG P Major facilitator superfamily
AIIGCJOP_02281 1.1e-172 cyoA 1.10.3.10, 1.10.3.12 C ubiquinol oxidase subunit
AIIGCJOP_02282 0.0 cyoB 1.10.3.10, 1.10.3.12, 1.9.3.1 C Belongs to the heme-copper respiratory oxidase family
AIIGCJOP_02283 2.5e-112 cyoC C PFAM cytochrome c oxidase, subunit III
AIIGCJOP_02284 7e-53 cyoD C cytochrome o ubiquinol oxidase
AIIGCJOP_02285 2.6e-158 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
AIIGCJOP_02287 1.1e-237 yajR EGP Major facilitator Superfamily
AIIGCJOP_02288 3.7e-82 yajQ S Belongs to the UPF0234 family
AIIGCJOP_02289 8.7e-162 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AIIGCJOP_02290 3e-102 thiJ 2.7.11.1, 3.5.1.124 S TIGRFAM DJ-1 family protein
AIIGCJOP_02291 9.6e-272 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AIIGCJOP_02292 6.4e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AIIGCJOP_02293 1.4e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AIIGCJOP_02294 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AIIGCJOP_02295 6.2e-182 yajO 1.1.1.91 C Aldo keto reductase
AIIGCJOP_02296 5.2e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AIIGCJOP_02297 1.1e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AIIGCJOP_02298 4.5e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
AIIGCJOP_02299 1.7e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AIIGCJOP_02300 1.5e-77 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AIIGCJOP_02301 4.5e-89 yajI M Lipoprotein
AIIGCJOP_02302 4.2e-177 tsx M nucleoside-specific channel-forming protein
AIIGCJOP_02303 9.8e-36
AIIGCJOP_02304 1.3e-166 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AIIGCJOP_02305 0.0 secD U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AIIGCJOP_02306 6e-52 yajC U Preprotein translocase
AIIGCJOP_02307 2.6e-224 tgt 2.4.2.29 J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AIIGCJOP_02308 8.9e-198 queA 2.4.2.29, 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AIIGCJOP_02309 1.9e-106 acpH 3.1.4.14 S Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AIIGCJOP_02310 1.1e-112 ahpC 1.11.1.15 O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AIIGCJOP_02311 2.4e-171 S Protein of unknown function (DUF3999)
AIIGCJOP_02312 0.0 S Predicted membrane protein (DUF2339)
AIIGCJOP_02313 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 13 family
AIIGCJOP_02314 5.2e-251 proY E Cryptic permease that may be involved in the transport of proline across the inner membrane
AIIGCJOP_02315 7.8e-228 brnQ P Component of the transport system for branched-chain amino acids
AIIGCJOP_02316 3.5e-241 phoR 2.7.13.3 T Histidine kinase
AIIGCJOP_02317 7.4e-129 K phosphate regulon transcriptional regulatory protein PhoB
AIIGCJOP_02318 2.2e-213 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AIIGCJOP_02319 0.0 sbcC L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AIIGCJOP_02320 1.7e-157 mak 2.7.1.4, 2.7.1.59 GK ROK family
AIIGCJOP_02321 4.1e-165 rdgC L May be involved in recombination
AIIGCJOP_02322 3.2e-46 ppnP 2.4.2.1, 2.4.2.2 S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions
AIIGCJOP_02323 4.7e-104 aroM E AroM protein
AIIGCJOP_02324 1e-27 yaiA S YaiA protein
AIIGCJOP_02325 1.1e-87 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AIIGCJOP_02326 4.8e-76 yaiI S Belongs to the UPF0178 family
AIIGCJOP_02327 3.2e-139 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AIIGCJOP_02328 4.1e-174 adrA 2.7.7.65 T Diguanylate cyclase
AIIGCJOP_02329 5.3e-21 psiF S Phosphate starvation-inducible protein, PSIF
AIIGCJOP_02330 1.9e-29 iraP S Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway
AIIGCJOP_02331 5e-205 pmrA EGP Major facilitator Superfamily
AIIGCJOP_02332 1.4e-122 S extensin
AIIGCJOP_02333 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AIIGCJOP_02334 3.7e-34 yaiZ S Protein of unknown function (DUF2754)
AIIGCJOP_02335 4.5e-46 yaiY S Protein of unknown function (DUF2755)
AIIGCJOP_02336 8.3e-199 yaiW S Lipoprotein
AIIGCJOP_02337 1.6e-222 sbmA I In Escherichia coli SbmA is involved in uptake of microcin J25
AIIGCJOP_02338 1.5e-206 ampH 3.4.16.4 V This protein has no known enzymatic function
AIIGCJOP_02339 1.1e-94 iprA T Involved in oxidative stress resistance
AIIGCJOP_02340 0.0 MU outer membrane autotransporter barrel
AIIGCJOP_02341 7.4e-175 hemB 4.2.1.24 H Belongs to the ALAD family
AIIGCJOP_02342 0.0 I Acyltransferase
AIIGCJOP_02343 3.4e-160 tauD 1.14.11.17 Q taurine catabolism dioxygenase
AIIGCJOP_02344 4.1e-126 tauC P ABC-type nitrate sulfonate bicarbonate transport system permease component
AIIGCJOP_02345 5.1e-131 tauB 3.6.3.36 P Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AIIGCJOP_02346 5.4e-170 tauA P taurine ABC transporter
AIIGCJOP_02347 7.7e-109 uhpA K response regulator
AIIGCJOP_02348 1.7e-271 uhpB 2.7.13.3 T Histidine kinase
AIIGCJOP_02349 2.5e-247 uhpC G transporter
AIIGCJOP_02350 1.3e-193 afuA P ABC-type Fe3 transport system, periplasmic component
AIIGCJOP_02351 0.0 afuB P Binding-protein-dependent transport system inner membrane component
AIIGCJOP_02352 1.8e-187 fbpC 3.6.3.30 P Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system
AIIGCJOP_02353 9.9e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
AIIGCJOP_02354 1.6e-255 mmuP E amino acid
AIIGCJOP_02356 5.2e-193 ydiK_1 S permease
AIIGCJOP_02357 4.8e-297 2.7.13.3 T (GGDEF) domain
AIIGCJOP_02358 1.3e-134 yfjM S Protein of unknown function DUF262
AIIGCJOP_02359 4.7e-44 ysdA K Membrane
AIIGCJOP_02360 2e-258 wcoR G Glucoamylase and related glycosyl hydrolases
AIIGCJOP_02361 3e-09 hicB S HicB family
AIIGCJOP_02362 3.3e-105 yagT 1.3.99.16 C Aerobic-type carbon monoxide dehydrogenase small subunit CoxS
AIIGCJOP_02363 6.8e-165 yagS 1.17.1.4 C Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AIIGCJOP_02364 0.0 yagR 1.17.1.4 C Xanthine dehydrogenase
AIIGCJOP_02365 2e-110 yagQ O Xanthine and CO dehydrogenases maturation factor XdhC CoxF family
AIIGCJOP_02366 1.7e-180 gntR K Bacterial regulatory proteins, lacI family
AIIGCJOP_02367 3.7e-131 yafS Q Methyl-transferase
AIIGCJOP_02368 1.6e-87 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AIIGCJOP_02369 6.3e-134 dnaQ 2.7.7.7, 3.1.26.4 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AIIGCJOP_02371 1.7e-72 C Prokaryotic cytochrome b561
AIIGCJOP_02372 2.8e-145 yafV 3.5.1.3 S Hydrolase
AIIGCJOP_02373 0.0 fadE I acyl-CoA dehydrogenase
AIIGCJOP_02374 3.4e-103 gmhA 5.3.1.28 G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
AIIGCJOP_02375 1e-150 yafJ S glutamine amidotransferase
AIIGCJOP_02376 3.3e-135 yafK S ErfK YbiS YcfS YnhG family protein
AIIGCJOP_02377 1e-232 nqrA 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AIIGCJOP_02378 7e-231 nqrB 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AIIGCJOP_02379 3.4e-138 nqrC 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AIIGCJOP_02380 4.8e-106 nqrD 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AIIGCJOP_02381 1.1e-99 nqrE 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AIIGCJOP_02382 2.4e-231 nqrF 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
AIIGCJOP_02383 6e-29 Z012_07620 2.7.1.180 S protein conserved in bacteria
AIIGCJOP_02384 2.1e-141 ugpQ_1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AIIGCJOP_02385 1e-190 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AIIGCJOP_02386 1.9e-275 pepD E aminoacyl-histidine dipeptidase
AIIGCJOP_02387 4.8e-84 gpt 2.4.2.22 F Acts on guanine, xanthine and to a lesser extent hypoxanthine
AIIGCJOP_02388 2.4e-239 frsA S Belongs to the UPF0255 family
AIIGCJOP_02389 6.3e-64 crl K Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32
AIIGCJOP_02390 3.7e-196 phoE M Belongs to the Gram-negative porin family
AIIGCJOP_02391 3.6e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AIIGCJOP_02392 1.4e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AIIGCJOP_02393 0.0 gmr_2 T Diguanylate cyclase
AIIGCJOP_02398 8e-296 purH 2.1.2.3, 3.5.4.10 F bifunctional purine biosynthesis protein purh
AIIGCJOP_02399 1e-240 purD 6.3.4.13 F Belongs to the GARS family
AIIGCJOP_02400 1.3e-109 yjaH S Protein of unknown function (DUF1481)
AIIGCJOP_02401 5.6e-40 hupA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AIIGCJOP_02402 1.3e-105 yjaG S protein conserved in bacteria
AIIGCJOP_02403 1.1e-124 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
AIIGCJOP_02404 3.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AIIGCJOP_02405 7.4e-146 nudC 1.3.7.1, 3.6.1.22 L nadh pyrophosphatase
AIIGCJOP_02406 4.7e-85 rsd K Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AIIGCJOP_02407 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AIIGCJOP_02408 2.8e-106 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
AIIGCJOP_02409 1e-123 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AIIGCJOP_02410 3.8e-25 thiS 2.8.1.10 H ThiS family
AIIGCJOP_02411 1.5e-133 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
AIIGCJOP_02412 6.7e-212 thiH 4.1.99.19 C In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS
AIIGCJOP_02413 1.9e-37 chbB 2.7.1.196, 2.7.1.205 G Phosphotransferase System
AIIGCJOP_02414 3.3e-47 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase System
AIIGCJOP_02415 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AIIGCJOP_02416 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AIIGCJOP_02417 2.7e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AIIGCJOP_02418 3.5e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AIIGCJOP_02419 5.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AIIGCJOP_02420 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AIIGCJOP_02421 9.7e-100 nusG K Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination
AIIGCJOP_02422 1.1e-57 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AIIGCJOP_02423 1.1e-29 bfd P could be a general redox and or regulatory component participating in the iron storage mobilization functions of BFR. Could participate in the release or the delivery of iron from to bacterioferritin (or other iron complexes)
AIIGCJOP_02424 2.3e-81 bfr 1.16.3.1 P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex
AIIGCJOP_02425 2e-70 hopD 3.4.23.43 NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AIIGCJOP_02426 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
AIIGCJOP_02427 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AIIGCJOP_02428 1.8e-102 rplD J Forms part of the polypeptide exit tunnel
AIIGCJOP_02429 1.9e-49
AIIGCJOP_02430 4.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AIIGCJOP_02431 1.9e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AIIGCJOP_02432 2.3e-51 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AIIGCJOP_02433 1.7e-125 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AIIGCJOP_02434 2.1e-70 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AIIGCJOP_02435 8.9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
AIIGCJOP_02436 1.2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AIIGCJOP_02437 9.3e-62 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AIIGCJOP_02438 1.2e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AIIGCJOP_02439 2.9e-96 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AIIGCJOP_02440 3.7e-48 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AIIGCJOP_02441 2.8e-64 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AIIGCJOP_02442 2.6e-89 rplF J is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AIIGCJOP_02443 2.3e-54 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AIIGCJOP_02444 1.6e-85
AIIGCJOP_02445 1.7e-24 rpmD J Ribosomal protein L30
AIIGCJOP_02446 3.9e-59 rplO J binds to the 23S rRNA
AIIGCJOP_02447 1.2e-241 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AIIGCJOP_02448 9.6e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AIIGCJOP_02449 2.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AIIGCJOP_02450 1.1e-181 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AIIGCJOP_02451 5.6e-62 rplQ J Ribosomal protein L17
AIIGCJOP_02452 7.4e-51 yhdN S PFAM DnaJ homologue, subfamily C, member 28, conserved domain
AIIGCJOP_02453 3.9e-72 zntR K transcriptional regulator
AIIGCJOP_02454 1e-22 arfA S protein conserved in bacteria
AIIGCJOP_02455 1.9e-55 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AIIGCJOP_02456 1.4e-251 trkA P found to be peripherally associated with the inner membrane in Escherichia coli
AIIGCJOP_02457 1.7e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AIIGCJOP_02458 3.1e-170 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AIIGCJOP_02459 1.5e-86 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AIIGCJOP_02460 8.5e-191 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
AIIGCJOP_02461 7.2e-83 smg S Belongs to the Smg family
AIIGCJOP_02462 8.5e-72 yrdD L dNA topoisomerase
AIIGCJOP_02463 3.1e-96 tsaC 2.7.7.87 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate
AIIGCJOP_02464 2.5e-136 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AIIGCJOP_02465 5.9e-36 yrdB S Protein of unknown function (DUF1488)
AIIGCJOP_02466 4.4e-84 yrdA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AIIGCJOP_02468 7.9e-35 vagC S Virulence-associated protein
AIIGCJOP_02469 1.5e-65 vapC S PIN domain
AIIGCJOP_02470 1.7e-224 L ATP-dependent endonuclease
AIIGCJOP_02471 2e-160 penP 3.5.2.6 V Beta-lactamase
AIIGCJOP_02472 3.1e-93 tnpR L Resolvase, N terminal domain
AIIGCJOP_02473 0.0 L Transposase
AIIGCJOP_02474 5.5e-57 L ATP-dependent endonuclease
AIIGCJOP_02475 1.9e-189 3.6.4.12 L DNA helicase
AIIGCJOP_02476 3.4e-143 mcrA L HNH endonuclease
AIIGCJOP_02477 1.6e-55 S Domain of unknown function (DUF305)
AIIGCJOP_02478 1e-35
AIIGCJOP_02479 3.2e-270 cusS 2.7.13.3 T Member of a two-component regulatory system
AIIGCJOP_02480 6.6e-122 KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_02481 4.7e-252 cusC MU Outer membrane efflux protein
AIIGCJOP_02482 4.6e-58 cusF S Copper binding periplasmic protein CusF
AIIGCJOP_02483 4.9e-243 cusB M Long alpha hairpin domain of cation efflux system protein, CusB
AIIGCJOP_02484 0.0 cusA P AcrB/AcrD/AcrF family
AIIGCJOP_02485 4.3e-74 copG S Protein of unknown function, DUF
AIIGCJOP_02486 0.0 pacS 3.6.3.4, 3.6.3.54 P P-type atpase
AIIGCJOP_02488 1.8e-133 2.7.1.50 M Peptidase family M23
AIIGCJOP_02489 1.2e-20 3.1.2.12 CE1 S Serine hydrolase involved in the detoxification of formaldehyde
AIIGCJOP_02490 1.5e-60 L Resolvase, N terminal domain
AIIGCJOP_02492 4.2e-64 S Protein of unknown function (DUF2787)
AIIGCJOP_02493 9.4e-74 radC L RadC-like JAB domain
AIIGCJOP_02494 8.1e-242 3.6.4.12 L D5 N terminal like
AIIGCJOP_02496 0.0 L Phage integrase family
AIIGCJOP_02498 1.3e-156 K AraC-like ligand binding domain
AIIGCJOP_02499 7.3e-93 E Lysine exporter protein (LYSE YGGA)
AIIGCJOP_02500 9.9e-103 yjdC K Transcriptional regulator
AIIGCJOP_02501 1.7e-296 dsbD 1.8.1.8 CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps
AIIGCJOP_02502 5.8e-52 cutA 4.2.3.1 P Involved in resistance toward heavy metals
AIIGCJOP_02503 1.7e-222 dcuA S Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AIIGCJOP_02504 1.4e-270 aspA 4.3.1.1 E Aspartate ammonia-lyase
AIIGCJOP_02505 2.8e-71 fxsA S protein affecting phage T7 exclusion by the F plasmid
AIIGCJOP_02506 3.6e-219 yjeH E amino acid
AIIGCJOP_02507 3.1e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AIIGCJOP_02508 7.3e-284 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AIIGCJOP_02509 5.2e-54 yjeI S Membrane
AIIGCJOP_02510 2.3e-47 yjeJ S YjeJ-like
AIIGCJOP_02512 2.2e-140 dkgB 1.1.1.346 S reductase
AIIGCJOP_02513 1.2e-160 yafC K Transcriptional regulator
AIIGCJOP_02514 6.8e-199 ytbD EGP Major facilitator Superfamily
AIIGCJOP_02515 5.7e-149 yafD S Endonuclease Exonuclease Phosphatase
AIIGCJOP_02516 8.8e-131 yafE Q methyltransferase
AIIGCJOP_02517 1.5e-211 mltD M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
AIIGCJOP_02518 2.5e-59 gloB 3.1.2.6 S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AIIGCJOP_02519 6.2e-85 ISPlu13C L Transposase
AIIGCJOP_02520 7.9e-11 uvrD-2 3.6.4.12 L DNA helicase
AIIGCJOP_02521 4.3e-144 folP 2.5.1.15 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AIIGCJOP_02522 2.7e-51 glmM 5.4.2.10 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
AIIGCJOP_02523 2.5e-291 M Putative transposase
AIIGCJOP_02524 9.1e-36
AIIGCJOP_02525 1.2e-121 parA L Resolvase, N terminal domain
AIIGCJOP_02526 3.2e-41 S MbeB-like, N-term conserved region
AIIGCJOP_02527 7.9e-21 S Relaxase/Mobilisation nuclease domain
AIIGCJOP_02530 3.3e-15
AIIGCJOP_02531 2.9e-36 ybaQ K addiction module antidote protein, HigA family
AIIGCJOP_02532 1.9e-47 S Bacterial mobilisation protein (MobC)
AIIGCJOP_02533 5.2e-145 csgG M Curli production assembly/transport component CsgG
AIIGCJOP_02534 3.7e-82 ycdZ S Protein of unknown function (DUF1097)
AIIGCJOP_02535 2.9e-99 ycdY S chaperone
AIIGCJOP_02536 4.6e-129 ycdX E Belongs to the PHP family
AIIGCJOP_02537 3.9e-173 ghrA 1.1.1.79, 1.1.1.81 EH D-isomer specific 2-hydroxyacid dehydrogenase
AIIGCJOP_02539 1.6e-163 V HNH endonuclease
AIIGCJOP_02540 3.8e-280 O heat shock protein binding
AIIGCJOP_02541 2.5e-50 symE J endoribonuclease activity
AIIGCJOP_02542 1.6e-29 S PAAR repeat-containing protein
AIIGCJOP_02543 7.1e-276 S type VI secretion-associated protein
AIIGCJOP_02544 0.0 S Intracellular multiplication and human macrophage-killing
AIIGCJOP_02547 4.1e-18 S Domain of unknown function (DUF4123)
AIIGCJOP_02549 5.6e-127 L transposition, DNA-mediated
AIIGCJOP_02550 0.0 1.1.1.169, 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydrogenase
AIIGCJOP_02551 6.7e-38 S PAAR motif
AIIGCJOP_02552 0.0 S Uncharacterized protein conserved in bacteria (DUF2345)
AIIGCJOP_02553 0.0 clpV O C-terminal, D2-small domain, of ClpB protein
AIIGCJOP_02554 4.1e-89 hcp S Type VI secretion system effector
AIIGCJOP_02555 3e-272 M Belongs to the ompA family
AIIGCJOP_02556 5.1e-122 S Type VI secretion system protein DotU
AIIGCJOP_02557 2.1e-244 S type VI secretion protein
AIIGCJOP_02558 2.9e-96 S Type VI secretion protein, EvpB/VC_A0108, tail sheath
AIIGCJOP_02559 3.1e-122 S type VI secretion protein
AIIGCJOP_02560 3.7e-50 S type VI secretion protein
AIIGCJOP_02561 7.5e-75 tssB S Type VI secretion system, VipA, VC_A0107 or Hcp2
AIIGCJOP_02562 3.8e-309 mppA E ABC transporter substrate-binding protein
AIIGCJOP_02563 1.3e-136 mpaA E Murein peptide amidase A
AIIGCJOP_02564 4.9e-163 ycjG 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
AIIGCJOP_02565 2.8e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AIIGCJOP_02566 1.1e-119 xylR 5.3.1.12 K Transcriptional regulator
AIIGCJOP_02567 1.9e-196 G Protein of unknown function (DUF1593)
AIIGCJOP_02568 9.2e-289 tyrR K Transcriptional regulator of aromatic amino acids metabolism
AIIGCJOP_02569 7e-163 ycjF S UPF0283 membrane protein
AIIGCJOP_02570 7.4e-269 ycjX S COG3106 Predicted ATPase
AIIGCJOP_02571 8.2e-169 ycjW K helix_turn _helix lactose operon repressor
AIIGCJOP_02572 3.1e-175 ompG M Outer membrane protein G (OmpG)
AIIGCJOP_02573 3.5e-194 msmK P Belongs to the ABC transporter superfamily
AIIGCJOP_02574 9.8e-102 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 G beta-phosphoglucomutase
AIIGCJOP_02575 0.0 ycjT 2.4.1.230 GH65 G hydrolase family 65, central catalytic
AIIGCJOP_02576 1.2e-183 ycjS S Oxidoreductase family, C-terminal alpha/beta domain
AIIGCJOP_02577 6.9e-147 ycjR G isomerase activity
AIIGCJOP_02578 3.5e-199 1.1.1.2 E L-arabinose catabolic process
AIIGCJOP_02579 3.6e-146 ycjP P ABC transporter (permease)
AIIGCJOP_02580 8.2e-157 ycjO P Binding-protein-dependent transport system inner membrane component
AIIGCJOP_02581 1.9e-223 ycjN G Sugar ABC transporter substrate-binding protein
AIIGCJOP_02582 1.7e-291 ycjM 2.4.1.7 GH13 G Alpha amylase catalytic
AIIGCJOP_02583 1.6e-29 pspD S Phage Shock Protein
AIIGCJOP_02584 3.8e-52 pspC KT phage shock protein C
AIIGCJOP_02585 3e-31 pspB S Phage shock protein B
AIIGCJOP_02586 1.8e-103 pspA KT Phage shock protein A
AIIGCJOP_02587 5.1e-168 pspF K transcriptional activator
AIIGCJOP_02588 1.6e-302 sapA E ABC transporter substrate-binding protein
AIIGCJOP_02589 2.1e-169 sapB P peptide transport system, permease
AIIGCJOP_02590 1.2e-142 sapC V peptide transport system, permease
AIIGCJOP_02591 1.8e-189 sapD P ATPase activity
AIIGCJOP_02592 2e-141 sapF P ATPase activity
AIIGCJOP_02593 2.8e-140 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AIIGCJOP_02594 1.2e-164 yciW S protein conserved in bacteria
AIIGCJOP_02595 0.0 rnb 3.1.13.1 J Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AIIGCJOP_02596 0.0 gmr 3.1.4.52 T Diguanylate cyclase
AIIGCJOP_02597 4e-164 rpfF I Enoyl-CoA hydratase
AIIGCJOP_02598 2.4e-18 yciZ S Belongs to the UPF0509 family
AIIGCJOP_02599 5.8e-124 yciT K transcriptional regulator
AIIGCJOP_02600 1.3e-23 osmB M Lipoprotein
AIIGCJOP_02601 3.6e-49 yciH J Translation Initiation Factor
AIIGCJOP_02602 9e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AIIGCJOP_02603 2.2e-213 lapB G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AIIGCJOP_02604 4.3e-44 lapA S Involved in the assembly of lipopolysaccharide (LPS)
AIIGCJOP_02605 1.7e-142 pgpB 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidylglycerophosphatase
AIIGCJOP_02606 1.2e-106 ribA 3.5.4.25 F Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
AIIGCJOP_02607 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AIIGCJOP_02608 9.6e-183 cysB K transcriptional regulator
AIIGCJOP_02609 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AIIGCJOP_02610 1.9e-37 yciN S Protein of unknown function (DUF2498)
AIIGCJOP_02611 8.8e-166 sohB OU peptidase
AIIGCJOP_02612 4.5e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AIIGCJOP_02613 4.6e-103 cobO 2.5.1.17 H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AIIGCJOP_02614 5.6e-158 rluB 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AIIGCJOP_02615 1.4e-86 S Type VI secretion system effector
AIIGCJOP_02616 4.5e-78 S Protein of unknown function (DUF2778)
AIIGCJOP_02617 2.1e-114 yciO 2.7.7.87 J Belongs to the SUA5 family
AIIGCJOP_02618 1.5e-155 trpH 3.1.3.97 S Metal-dependent phosphoesterases (PHP family)
AIIGCJOP_02619 1.2e-275 trpE 4.1.3.27 H Anthranilate synthase component
AIIGCJOP_02620 7.3e-297 trpD 2.4.2.18, 2.6.1.85, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AIIGCJOP_02621 1.7e-241 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
AIIGCJOP_02622 1.3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AIIGCJOP_02623 2.2e-140 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AIIGCJOP_02624 1.5e-225 yedE S transporter component
AIIGCJOP_02625 2.2e-37 yedF O Sulfurtransferase TusA
AIIGCJOP_02626 8.1e-39 S Bacterial protein of unknown function (DUF883)
AIIGCJOP_02628 2.8e-46
AIIGCJOP_02629 1.4e-21
AIIGCJOP_02630 6.4e-41 S peptidoglycan catabolic process
AIIGCJOP_02632 4.2e-61 NT transmembrane signaling receptor activity
AIIGCJOP_02633 0.0 NT Phage-related protein, tail component
AIIGCJOP_02634 7.1e-75 S Corresponds to locus_tag
AIIGCJOP_02635 3.9e-107 S peptidoglycan catabolic process
AIIGCJOP_02636 4.2e-122 L S TIGRFAM phage minor tail protein L
AIIGCJOP_02637 4e-51 S Phage minor tail protein
AIIGCJOP_02638 0.0 sca1 D Lambda phage tail tape-measure protein (Tape_meas_lam_C)
AIIGCJOP_02639 2.1e-37 GJ12_01675 S phage tail assembly protein T
AIIGCJOP_02640 5.2e-45 S Bacteriophage lambda tail assembly chaperone, TAC, protein G
AIIGCJOP_02641 2.9e-115 S peptidase activity
AIIGCJOP_02642 8.8e-50 S Phage minor tail protein U
AIIGCJOP_02643 8.1e-70 JD73_18875 S prophage
AIIGCJOP_02644 5e-28 S ATP-binding sugar transporter from pro-phage
AIIGCJOP_02645 3.8e-35 S Uncharacterized conserved protein (DUF2190)
AIIGCJOP_02646 0.0 clpP 3.4.21.92 E Clp protease
AIIGCJOP_02647 7.5e-227 S portal protein
AIIGCJOP_02648 3e-23
AIIGCJOP_02649 0.0 S Phage terminase large subunit (GpA)
AIIGCJOP_02650 2.5e-70 S Protein of unknown function (DUF1441)
AIIGCJOP_02651 6e-15 S Uncharacterized conserved protein (DUF2190)
AIIGCJOP_02652 4.6e-09 gvpU S gas vesicle protein
AIIGCJOP_02653 5.2e-49
AIIGCJOP_02654 2.6e-91 rrrD 3.2.1.17 G lysozyme
AIIGCJOP_02655 4.3e-36 essD S Bacteriophage P21 holin S
AIIGCJOP_02656 3.1e-84 sppA OU Serine dehydrogenase proteinase
AIIGCJOP_02657 1.4e-102
AIIGCJOP_02658 5.3e-168 ydfU V Protein of unknown function (DUF968)
AIIGCJOP_02659 8.4e-60 L endodeoxyribonuclease RusA
AIIGCJOP_02660 1e-14
AIIGCJOP_02661 1e-34 dinI S SOS response
AIIGCJOP_02662 7.5e-46
AIIGCJOP_02663 6.5e-115 yhdJ 2.1.1.72 L DNA methylase
AIIGCJOP_02664 8.6e-20
AIIGCJOP_02665 1.3e-41 glpR GK Bacterial protein of unknown function (DUF977)
AIIGCJOP_02666 3.4e-68 K PerC transcriptional activator
AIIGCJOP_02667 1.2e-78 S Replication protein P
AIIGCJOP_02668 7.1e-82 S Putative bacterial toxin ydaT
AIIGCJOP_02669 3.4e-16 K Helix-turn-helix XRE-family like proteins
AIIGCJOP_02670 2.2e-07
AIIGCJOP_02672 2.4e-48 iscR 2.8.1.7 K Transcriptional regulator
AIIGCJOP_02673 0.0 2.7.7.7 L 3' exoribonuclease, RNase T-like
AIIGCJOP_02674 7.3e-150 L Belongs to the 'phage' integrase family
AIIGCJOP_02675 3.3e-115 ompW M outer membrane protein W
AIIGCJOP_02676 2.9e-115 yciC S UPF0259 membrane protein
AIIGCJOP_02677 1.1e-92 ispZ D probably involved in intracellular septation
AIIGCJOP_02678 9.3e-68 yciA I Thioesterase superfamily
AIIGCJOP_02679 1.8e-69 tonB M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AIIGCJOP_02680 6.8e-47 yciI T YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the
AIIGCJOP_02681 1.6e-104 leuE E Efflux Protein
AIIGCJOP_02682 1.2e-19
AIIGCJOP_02683 1e-276 cls 2.7.8.8 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AIIGCJOP_02684 2.8e-57 yciU S Belongs to the UPF0263 family
AIIGCJOP_02685 1.1e-189 oppF P Belongs to the ABC transporter superfamily
AIIGCJOP_02686 1.7e-182 oppD P Belongs to the ABC transporter superfamily
AIIGCJOP_02687 1.3e-144 oppC P COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components
AIIGCJOP_02688 6.7e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AIIGCJOP_02689 0.0 oppA E ABC transporter substrate-binding protein
AIIGCJOP_02691 2.3e-108 ychE U UPF0056 membrane protein
AIIGCJOP_02692 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AIIGCJOP_02693 1.5e-101 tdk 2.7.1.21 F thymidine kinase
AIIGCJOP_02694 5.2e-61 hns K Belongs to the histone-like protein H-NS family
AIIGCJOP_02695 2.4e-164 galU 2.7.7.9 M Utp--glucose-1-phosphate uridylyltransferase
AIIGCJOP_02696 1.6e-177 KT Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation
AIIGCJOP_02697 3.1e-151 rssA S Patatin-like phospholipase
AIIGCJOP_02698 1.1e-158 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
AIIGCJOP_02701 5.9e-71 lrpC K AsnC family transcriptional regulator
AIIGCJOP_02702 4.1e-140 yxxF EG EamA-like transporter family
AIIGCJOP_02703 2.3e-122 narI 1.7.5.1 C nitrate reductase, gamma subunit
AIIGCJOP_02704 2.6e-121 narJ 1.7.5.1 C nitrate reductase molybdenum cofactor assembly chaperone
AIIGCJOP_02705 1.1e-310 narH 1.7.5.1 C nitrate reductase beta subunit
AIIGCJOP_02706 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_02707 2e-258 narK P nitrate nitrite transporter
AIIGCJOP_02708 3.9e-291 narX 2.7.13.3 T Histidine kinase
AIIGCJOP_02709 1.3e-111 narL K response regulator
AIIGCJOP_02710 2.7e-234 ychO 3.2.1.14 GH18 M entry into host
AIIGCJOP_02711 0.0 nasA 1.7.7.2 C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism
AIIGCJOP_02712 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AIIGCJOP_02713 7.9e-143 nasD 3.6.3.36 P (ABC) transporter
AIIGCJOP_02714 1.9e-153 nasE P ABC-type nitrate sulfonate bicarbonate transport system permease component
AIIGCJOP_02715 2.4e-234 nasF P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AIIGCJOP_02716 7.3e-145 nasR K ANTAR
AIIGCJOP_02717 1.9e-56 ychN P conserved protein involved in intracellular sulfur reduction
AIIGCJOP_02718 2.3e-251 cheD2 NT chemotaxis, protein
AIIGCJOP_02719 4.7e-38 S Protein involved in biological_process
AIIGCJOP_02720 4.1e-127 chaC P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AIIGCJOP_02721 4.6e-35 chaB K Might be a regulator of the sodium-potassium proton antiporter ChaA
AIIGCJOP_02722 2.6e-184 chaA P Calcium Proton
AIIGCJOP_02723 1.4e-156 M 2-dehydro-3-deoxyphosphooctonate aldolase
AIIGCJOP_02724 2.5e-152 ychA S Transglutaminase-like superfamily
AIIGCJOP_02725 1.8e-63 sirB2 S Invasion gene expression up-regulator SirB
AIIGCJOP_02726 2.2e-135 prmC 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AIIGCJOP_02727 1.4e-195 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AIIGCJOP_02728 2.5e-223 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AIIGCJOP_02729 3.7e-108 lolB M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AIIGCJOP_02730 4e-156 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AIIGCJOP_02731 3.3e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AIIGCJOP_02732 1.2e-270 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
AIIGCJOP_02733 1.4e-147 nolA K helix_turn_helix, mercury resistance
AIIGCJOP_02734 1.5e-43 ychH S Protein of unknown function (DUF2583)
AIIGCJOP_02735 3e-107 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AIIGCJOP_02736 3.2e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AIIGCJOP_02737 1.1e-165 ftrA K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
AIIGCJOP_02738 6.6e-66 XK27_05625 P Rhodanese
AIIGCJOP_02739 3.1e-246 fcy21 U Belongs to the purine-cytosine permease (2.A.39) family
AIIGCJOP_02740 0.0 cbbbC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_02741 6.5e-61 yybH S SnoaL-like domain
AIIGCJOP_02742 7.1e-69
AIIGCJOP_02743 2.3e-40 azlD S branched-chain amino acid
AIIGCJOP_02744 5.7e-103 azlC E branched-chain amino acid
AIIGCJOP_02745 1.1e-43 S Fusaric acid resistance protein-like
AIIGCJOP_02746 2.8e-171 catA 1.13.11.1 Q catechol 1,2-dioxygenase
AIIGCJOP_02747 3e-44 catC 5.3.3.4 Q muconolactone delta-isomerase
AIIGCJOP_02748 2.4e-193 catB 5.5.1.1 M Belongs to the mandelate racemase muconate lactonizing enzyme family
AIIGCJOP_02749 1.8e-115 pcaD 3.1.1.24, 4.1.1.44 I 3-oxoadipate enol-lactonase
AIIGCJOP_02750 2.5e-118 pcaJ 2.8.3.6 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
AIIGCJOP_02751 1.8e-119 pcaI 2.8.3.6 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AIIGCJOP_02752 1e-232 EGP Major facilitator superfamily
AIIGCJOP_02753 4.7e-85 hpaC 1.5.1.36 S Flavin reductase
AIIGCJOP_02754 1.5e-137 C Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1
AIIGCJOP_02755 1.3e-118 IQ reductase
AIIGCJOP_02756 1.2e-82 hcaA2 Q Aromatic-ring-hydroxylating dioxygenase
AIIGCJOP_02757 2.1e-249 antA P Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit
AIIGCJOP_02758 1.2e-83 S SnoaL-like domain
AIIGCJOP_02759 1.2e-61
AIIGCJOP_02760 1.3e-204 1.14.13.235 I acyl-CoA dehydrogenase
AIIGCJOP_02761 1.1e-169 gatA 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
AIIGCJOP_02762 7.3e-72 K transcriptional regulator
AIIGCJOP_02763 5.6e-237 G Major facilitator superfamily
AIIGCJOP_02764 8.3e-15
AIIGCJOP_02765 9.2e-125 S phage-encoded protein
AIIGCJOP_02766 1.6e-154 S Zn-dependent hydrolases, including glyoxylases
AIIGCJOP_02767 1.4e-139 S Protein of unknown function (DUF1264)
AIIGCJOP_02768 3.7e-209 rafY S Porin-like glycoporin RafY
AIIGCJOP_02769 4e-219 G COG2211 Na melibiose symporter and related transporters
AIIGCJOP_02771 0.0 treA 3.2.1.28 GH37 G Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AIIGCJOP_02772 3e-35 ymgE S transglycosylase associated protein
AIIGCJOP_02773 2.8e-126 ycgR M Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AIIGCJOP_02774 8.6e-113 emtA GH23 M Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain
AIIGCJOP_02775 1.5e-158 ldcA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
AIIGCJOP_02776 2.4e-311 nhaP2 P K( ) H( ) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels
AIIGCJOP_02777 1.7e-196 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AIIGCJOP_02778 1.4e-250 dadA 1.4.5.1 E Oxidative deamination of D-amino acids
AIIGCJOP_02779 7.7e-304 spoVR S SpoVR family
AIIGCJOP_02780 2e-132 fadR K Multifunctional regulator of fatty acid metabolism
AIIGCJOP_02781 9e-236 nhaB P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AIIGCJOP_02782 1.1e-95 dsbB O Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AIIGCJOP_02783 7.9e-84 ycgN S Belongs to the UPF0260 family
AIIGCJOP_02784 7.8e-120 ycgM Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
AIIGCJOP_02785 3.6e-42 ycgL S YcgL domain-containing protein
AIIGCJOP_02786 2.2e-112 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AIIGCJOP_02787 3.3e-144 minD D Belongs to the ParA family
AIIGCJOP_02788 2.5e-40 minE D Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AIIGCJOP_02789 2.5e-209 rnd 3.1.13.5 J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AIIGCJOP_02790 0.0 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
AIIGCJOP_02791 9.8e-74 yeaY M Outer Membrane Lipoprotein
AIIGCJOP_02792 3.6e-115 yeaZ 2.3.1.234 O PFAM Peptidase M22, glycoprotease
AIIGCJOP_02793 0.0 dinG 3.6.4.12 KL helicase
AIIGCJOP_02794 5.4e-56 yoaB J Translation Initiation Inhibitor YjgF Family
AIIGCJOP_02795 2.7e-22 yoaH S Belongs to the UPF0181 family
AIIGCJOP_02796 1.6e-241 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AIIGCJOP_02797 3.3e-98 nudL L NUDIX hydrolase
AIIGCJOP_02798 2.9e-254 sdaA 4.3.1.17 E PFAM Serine dehydratase alpha chain
AIIGCJOP_02799 3.5e-270 adrB 3.1.4.52 T EAL domain
AIIGCJOP_02800 1.8e-279 yoaE P membrane protein, terc
AIIGCJOP_02801 2e-151 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
AIIGCJOP_02802 8.2e-132 manY G pts system
AIIGCJOP_02803 2.5e-155 manZ G PTS system mannose fructose sorbose family IID component
AIIGCJOP_02804 4.5e-66 yobD S UPF0266 membrane protein
AIIGCJOP_02805 5.5e-104 mntP P Probably functions as a manganese efflux pump
AIIGCJOP_02806 4e-142 rrmA 2.1.1.187 Q Methyl-transferase
AIIGCJOP_02807 0.0 ftsI 3.4.16.4 M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum
AIIGCJOP_02808 1.1e-32 cspC K Cold shock
AIIGCJOP_02809 8e-177 3.1.4.54 S Zn-dependent hydrolases of the beta-lactamase fold
AIIGCJOP_02810 4e-36 yebO S YebO-like protein
AIIGCJOP_02811 5.3e-34 yobH S YobH-like protein
AIIGCJOP_02812 5.6e-141 kdgR K transcriptional regulator
AIIGCJOP_02813 1.1e-232 yebQ EGP Major facilitator Superfamily
AIIGCJOP_02814 1.5e-150 htpX O Belongs to the peptidase M48B family
AIIGCJOP_02815 0.0 prc 3.4.21.102 M Belongs to the peptidase S41A family
AIIGCJOP_02816 7.7e-78 proQ T RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AIIGCJOP_02817 6.4e-82 yebR 1.8.4.14 T Domain present in phytochromes and cGMP-specific phosphodiesterases.
AIIGCJOP_02818 4e-221 yebS S paraquat-inducible protein A
AIIGCJOP_02819 0.0 yebT Q paraquat-inducible protein b
AIIGCJOP_02820 3.5e-255 rsmF 2.1.1.176, 2.1.1.178 J Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AIIGCJOP_02821 1.1e-38 yebV S Protein of unknown function (DUF1480)
AIIGCJOP_02822 1.1e-29 yebW S Protein of unknown function (DUF1482)
AIIGCJOP_02823 7.4e-107 pphA 3.1.3.16 T Serine Threonine protein
AIIGCJOP_02824 1.4e-149 virK S protein conserved in bacteria
AIIGCJOP_02825 1e-54 yebY S Protein of unknown function (DUF2511)
AIIGCJOP_02826 5.6e-134 yebZ P copper resistance protein
AIIGCJOP_02827 6.4e-47 yobA S Resistance protein
AIIGCJOP_02828 2.5e-33 holE 2.7.7.7 L DNA polymerase III
AIIGCJOP_02829 2.4e-95 yobB 6.3.5.1 S Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds and nitrogen compound metabolic process
AIIGCJOP_02830 3.9e-127 exoX L 3'-5' exonuclease activity on single or double-strand DNA
AIIGCJOP_02831 0.0 ptrB 3.4.21.83 E Protease II
AIIGCJOP_02832 1.9e-102 yebE S protein conserved in bacteria
AIIGCJOP_02833 3.8e-49 yebF S YebF-like protein
AIIGCJOP_02834 1e-202 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AIIGCJOP_02835 4.8e-114 eda 4.1.2.14, 4.1.3.42 G Aldolase
AIIGCJOP_02836 0.0 edd 4.2.1.12 EG Belongs to the IlvD Edd family
AIIGCJOP_02837 4.2e-283 zwf 1.1.1.363, 1.1.1.49 H Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AIIGCJOP_02838 1.5e-150 hexR K transcriptional regulator
AIIGCJOP_02839 6.9e-262 pyk 2.7.1.40 G Belongs to the pyruvate kinase family
AIIGCJOP_02840 5.6e-183 lpxM 2.3.1.241, 2.3.1.242, 2.3.1.243 M Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A
AIIGCJOP_02841 6.1e-241 yebA M COG0739 Membrane proteins related to metalloendopeptidases
AIIGCJOP_02842 2.9e-158 znuA P Zinc-uptake complex component A periplasmic
AIIGCJOP_02843 2.1e-137 znuC P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system
AIIGCJOP_02844 1.3e-110 znuB P COG1108 ABC-type Mn2 Zn2 transport systems permease components
AIIGCJOP_02845 1.1e-184 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AIIGCJOP_02846 4.7e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AIIGCJOP_02847 2.8e-88 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AIIGCJOP_02848 3.1e-125 yebC K transcriptional regulatory protein
AIIGCJOP_02849 2e-74 nudB 2.3.1.181, 3.6.1.13, 3.6.1.55, 3.6.1.67 L NUDIX domain
AIIGCJOP_02850 0.0 aspS 6.1.1.12 J L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AIIGCJOP_02851 2.6e-95 yecD Q Isochorismatase family
AIIGCJOP_02852 8.6e-13 yecE S Protein of unknown function DUF72
AIIGCJOP_02853 1e-32 S DinI-like family
AIIGCJOP_02855 1.8e-64 S N-acetylmuramoyl-L-alanine amidase activity
AIIGCJOP_02857 2.1e-60 NT transmembrane signaling receptor activity
AIIGCJOP_02858 0.0 NT Phage-related protein, tail component
AIIGCJOP_02861 4.7e-76 S virus tail assembly
AIIGCJOP_02862 1.4e-135 3.5.1.28 M JAB/MPN domain
AIIGCJOP_02863 4.4e-135 S Phage minor tail protein L
AIIGCJOP_02864 2e-55 S Phage minor tail protein
AIIGCJOP_02865 2.7e-150 M tape measure protein
AIIGCJOP_02867 3.4e-21 S Protein of unknown function (DUF4035)
AIIGCJOP_02868 1.5e-33 S Phage tail assembly chaperone
AIIGCJOP_02869 3.6e-55
AIIGCJOP_02870 1e-51 S Protein of unknown function (DUF3168)
AIIGCJOP_02871 1.5e-74 S Bacteriophage HK97-gp10, putative tail-component
AIIGCJOP_02872 2.8e-36 S Phage head-tail joining protein
AIIGCJOP_02873 1.1e-47 S Phage gp6-like head-tail connector protein
AIIGCJOP_02874 3.3e-07
AIIGCJOP_02875 1.5e-212 xkdG S capsid protein
AIIGCJOP_02876 4.1e-137 clpP 3.4.21.92 OU ATP-dependent Clp protease proteolytic subunit
AIIGCJOP_02877 2.7e-233 S Phage portal protein, HK97 family
AIIGCJOP_02878 4.6e-289 S Phage Terminase
AIIGCJOP_02879 4.1e-70 S Phage terminase, small subunit
AIIGCJOP_02880 2e-31 L NUMOD4 domain protein
AIIGCJOP_02881 6.2e-55 L Endonuclease
AIIGCJOP_02883 6.2e-78 S Phage regulatory protein Rha (Phage_pRha)
AIIGCJOP_02884 1e-20
AIIGCJOP_02885 9e-98 S secretion activating protein
AIIGCJOP_02886 9.1e-17 S Putative 3TM holin, Phage_holin_3
AIIGCJOP_02887 1.3e-08 S Putative phage holin
AIIGCJOP_02888 7.1e-40 L COG2801 Transposase and inactivated derivatives
AIIGCJOP_02889 2.2e-156 L Transposase and inactivated derivatives
AIIGCJOP_02890 7e-26
AIIGCJOP_02892 3.5e-106 rlfA S Protein of unknown function (DUF3800)
AIIGCJOP_02893 8.4e-100 O Antitermination protein
AIIGCJOP_02894 9.2e-49 S sequence-specific DNA binding transcription factor activity
AIIGCJOP_02895 6.5e-155 S Zinc-binding domain of primase-helicase
AIIGCJOP_02896 1.1e-273 res L helicase
AIIGCJOP_02897 1.2e-14 croE S protein conserved in bacteria, prophage-related
AIIGCJOP_02898 3.7e-23 KT Peptidase S24-like
AIIGCJOP_02902 1.1e-41
AIIGCJOP_02903 8.3e-27
AIIGCJOP_02904 5e-15
AIIGCJOP_02905 1.3e-37
AIIGCJOP_02906 4.3e-142 S ORF6N domain
AIIGCJOP_02907 9.4e-10
AIIGCJOP_02908 2.7e-33 S Putative excisionase (DUF1233)
AIIGCJOP_02909 3.6e-241 intR L Pfam:DUF3596
AIIGCJOP_02910 4.7e-134 yecE S Protein of unknown function DUF72
AIIGCJOP_02911 6e-67 yecN S relative of glutathione S-transferase, MAPEG superfamily
AIIGCJOP_02912 4.6e-137 cmoA Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)
AIIGCJOP_02913 1.2e-182 cmoB J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs
AIIGCJOP_02914 2.8e-126 cutC P Participates in the control of copper homeostasis
AIIGCJOP_02915 8.2e-102 yecM S protein conserved in bacteria
AIIGCJOP_02916 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
AIIGCJOP_02917 1.7e-223 yesR 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
AIIGCJOP_02918 4.9e-293 G Major Facilitator
AIIGCJOP_02919 1.3e-29 yhaI S Protein of unknown function (DUF805)
AIIGCJOP_02920 8.2e-12
AIIGCJOP_02921 1.3e-61 flhE N Flagellar protein flhE
AIIGCJOP_02922 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AIIGCJOP_02923 4.6e-208 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AIIGCJOP_02924 1.2e-109 cheZ NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AIIGCJOP_02925 6.1e-64 KT Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble
AIIGCJOP_02926 3.9e-190 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
AIIGCJOP_02927 6.6e-159 cheR 2.1.1.80 NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AIIGCJOP_02928 1.2e-150 tap NT chemotaxis
AIIGCJOP_02929 4.6e-193 tar NT chemotaxis, protein
AIIGCJOP_02930 3.5e-145 csuE S spore coat U domain protein
AIIGCJOP_02931 0.0 csuD M Fimbrial biogenesis outer membrane usher protein
AIIGCJOP_02932 1.7e-110 csuC M chaperone
AIIGCJOP_02933 1.8e-69 csuB S Spore Coat Protein U domain
AIIGCJOP_02934 2.4e-85 csuA S spore coat U domain protein
AIIGCJOP_02935 4.8e-85 cheW NT chemotaxis signal transduction protein
AIIGCJOP_02936 0.0 cheA 2.7.13.3 T COG0643 Chemotaxis protein histidine kinase and related kinases
AIIGCJOP_02937 2.9e-168 motB N Flagellar Motor Protein
AIIGCJOP_02938 5.5e-153 motA N With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
AIIGCJOP_02939 1.8e-104 flhC K Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways
AIIGCJOP_02940 6.8e-54 flhD K Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways
AIIGCJOP_02941 1.4e-64 uspC T Required for resistance to DNA-damaging agents
AIIGCJOP_02942 2.4e-267 otsA 2.4.1.15, 2.4.1.347 GT20 G Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AIIGCJOP_02943 6.4e-140 otsB 2.4.1.15, 2.4.1.347, 3.1.3.12 GT20 G Removes the phosphate from trehalose 6-phosphate to produce free trehalose
AIIGCJOP_02944 2.6e-156 araH G Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_02945 6.7e-284 araG 3.6.3.17 P Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system
AIIGCJOP_02946 3.3e-183 araF G l-arabinose-binding periplasmic protein
AIIGCJOP_02947 5.8e-92 thiJ 2.7.11.1, 3.5.1.124 S Thij pfpi
AIIGCJOP_02948 9.6e-78 ftnA 1.16.3.2 P Iron-storage protein
AIIGCJOP_02949 2.3e-35 yecJ S Protein of unknown function (DUF2766)
AIIGCJOP_02950 2.7e-242 EGP Major facilitator Superfamily
AIIGCJOP_02951 7.8e-117 YPO1991 5.3.1.26, 5.3.1.6 G isomerase
AIIGCJOP_02952 2.9e-41 yecR S YecR-like lipoprotein
AIIGCJOP_02953 4.3e-86 ftnA 1.16.3.2 P Iron-storage protein
AIIGCJOP_02954 3.8e-32 yecH S Protein of unknown function (DUF2492)
AIIGCJOP_02955 3e-54
AIIGCJOP_02956 5.7e-209 tyrP E amino acid
AIIGCJOP_02957 2.5e-126 yecA C Belongs to the UPF0149 family
AIIGCJOP_02958 5.3e-209 livJ E With LivFGHM is involved in the high affinity leucine transport
AIIGCJOP_02959 1.3e-160 livH E Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_02960 1.5e-220 livM U Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_02961 9.3e-161 livG E Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids
AIIGCJOP_02962 5.7e-124 livF P Branched-chain amino acid transport
AIIGCJOP_02963 4.7e-272 2.7.8.42, 2.7.8.43 S membrane-associated metal-dependent hydrolase
AIIGCJOP_02964 4.2e-38 copZ P Heavy-metal-associated domain
AIIGCJOP_02965 3.5e-50 S mercuric transport protein
AIIGCJOP_02966 6.5e-215 E Transglutaminase-like enzymes
AIIGCJOP_02967 8.2e-174 lsrB_2 G (ABC) transporter
AIIGCJOP_02968 1.1e-249 3.6.3.17 G ABC transporter
AIIGCJOP_02969 8.8e-160 U Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_02970 4.3e-151 G Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_02975 9.1e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AIIGCJOP_02976 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AIIGCJOP_02977 2.2e-82 uvrY K response regulator
AIIGCJOP_02978 2.1e-155 K transcriptional regulator
AIIGCJOP_02979 3.1e-153 yhhW_1 S Pirin C-terminal cupin domain
AIIGCJOP_02980 4.9e-101 Q COG1335 Amidases related to nicotinamidase
AIIGCJOP_02982 8e-139 L Transposase IS66 family
AIIGCJOP_02983 6.1e-48 L IS1 transposase
AIIGCJOP_02984 2.1e-48 L cog cog1662
AIIGCJOP_02985 3.3e-112 L Transposase and inactivated derivatives
AIIGCJOP_02986 1.9e-40 L Transposase
AIIGCJOP_02987 7.2e-64 S Domain of unknown function (DUF4385)
AIIGCJOP_02988 2.7e-233 kgtP EGP transporter
AIIGCJOP_02989 9e-53 yfiM S Required for high salt suppression of motility
AIIGCJOP_02990 1.6e-257 pssA 2.7.8.8 I Catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine
AIIGCJOP_02991 0.0 yfiQ C Acyl-CoA synthetase (NDP forming)
AIIGCJOP_02992 1.3e-117 yfiP S DTW domain containing protein
AIIGCJOP_02993 1.5e-76 trxC 1.8.1.8 O Thioredoxin
AIIGCJOP_02994 1.3e-183 yfiF 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AIIGCJOP_02995 4.5e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AIIGCJOP_02996 3.9e-63 grcA 1.14.13.236 S Acts as a radical domain for damaged PFL and possibly other radical proteins
AIIGCJOP_02997 4.3e-210 srmB 3.6.4.13 F DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity
AIIGCJOP_02998 1.5e-127 yfiC 2.1.1.223, 2.1.1.72 J Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AIIGCJOP_02999 7.9e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
AIIGCJOP_03000 3.5e-100 rpoE K Belongs to the sigma-70 factor family. ECF subfamily
AIIGCJOP_03001 3.5e-88 rseA T An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AIIGCJOP_03002 1.4e-165 rseB T Negative regulator of sigma E activity
AIIGCJOP_03003 8e-74 rseC T Positive regulator of
AIIGCJOP_03004 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AIIGCJOP_03005 3e-184 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AIIGCJOP_03006 7.8e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AIIGCJOP_03007 2.5e-169 era J An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AIIGCJOP_03008 4.4e-115 recO 2.6.99.2 L Involved in DNA repair and RecF pathway recombination
AIIGCJOP_03009 6.2e-129 pdxJ 2.6.99.2 H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AIIGCJOP_03010 1.3e-63 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AIIGCJOP_03011 1.9e-45 yfhL C Ferredoxin
AIIGCJOP_03012 2.9e-143 yfhH K Transcriptional regulator
AIIGCJOP_03013 4.4e-150 murQ 4.2.1.126 S Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AIIGCJOP_03014 3.8e-230 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is
AIIGCJOP_03015 1.9e-118 yfhB 3.1.3.27 E HAD superfamily (Subfamily IF) hydrolase, YfhB
AIIGCJOP_03016 4.2e-87 tadA 3.4.17.13, 3.5.4.1, 3.5.4.3, 3.5.4.33, 3.8.1.5 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AIIGCJOP_03017 4.5e-275 mltF M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella
AIIGCJOP_03018 0.0 purL 6.3.5.3 F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
AIIGCJOP_03019 1.3e-228 T PhoQ Sensor
AIIGCJOP_03020 5.8e-122 yfhG NU YfhG lipoprotein
AIIGCJOP_03021 2.4e-245 yfhA T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
AIIGCJOP_03022 2e-55 glnB K nitrogen regulatory protein P-II
AIIGCJOP_03023 6.8e-215 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AIIGCJOP_03024 2.3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AIIGCJOP_03025 4.9e-67 yphA S SURF4 family
AIIGCJOP_03026 9.3e-188 yphH 2.7.1.2 GK ROK family
AIIGCJOP_03027 0.0 S Domain of unknown function (DUF5107)
AIIGCJOP_03028 6.1e-234 EGP Major facilitator Superfamily
AIIGCJOP_03029 2.8e-106 yphB 5.1.3.3 G Aldose 1-epimerase
AIIGCJOP_03030 1.5e-203 hcaT 1.5.1.2 EGP Major facilitator Superfamily
AIIGCJOP_03031 6.8e-229 csiE K Stationary phase inducible protein CsiE
AIIGCJOP_03032 3.3e-107 MA20_06510 2.7.4.1 S transport system periplasmic component
AIIGCJOP_03033 3.4e-164 yohM P Belongs to the NiCoT transporter (TC 2.A.52) family
AIIGCJOP_03035 2e-146 suhB 3.1.3.25 G Inositol monophosphatase
AIIGCJOP_03036 2.3e-128 trmJ 2.1.1.200, 3.5.1.19, 6.1.1.16 J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AIIGCJOP_03037 6.1e-85 iscR 2.8.1.7 K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins
AIIGCJOP_03038 9e-231 iscS 2.8.1.7 E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
AIIGCJOP_03039 8.5e-66 iscU C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters
AIIGCJOP_03040 2.4e-53 iscA C iron-sulfur cluster assembly protein
AIIGCJOP_03041 1.4e-87 hscB O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AIIGCJOP_03042 0.0 hscA O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AIIGCJOP_03043 6.7e-59 fdx C Ferredoxin, 2Fe-2S type, ISC system
AIIGCJOP_03044 4.9e-33 iscX S Fe-S assembly protein IscX
AIIGCJOP_03045 1.1e-239 pepB 3.4.11.1, 3.4.11.23 E Probably plays an important role in intracellular peptide degradation
AIIGCJOP_03046 1.6e-140 sseB S enhanced serine sensitivity protein SseB
AIIGCJOP_03047 4.4e-130 K Transcriptional regulator
AIIGCJOP_03048 6.9e-161 sseA 2.8.1.1, 2.8.1.2 P sulfurtransferase
AIIGCJOP_03049 8.5e-262 malH 3.2.1.122, 3.2.1.86 GH4,GT4 G 6-phospho-alpha-glucosidase
AIIGCJOP_03050 2.6e-275 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system
AIIGCJOP_03051 0.0 yfhM P Large extracellular alpha-helical protein
AIIGCJOP_03052 0.0 pbpC 2.4.1.129 GT51 M penicillin-binding protein 1C
AIIGCJOP_03053 5e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AIIGCJOP_03054 6.2e-221 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AIIGCJOP_03055 3.4e-122 rodZ S Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis
AIIGCJOP_03056 1.1e-203 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AIIGCJOP_03057 5.9e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
AIIGCJOP_03058 9.3e-99 yfgM S Tetratricopeptide repeat-like domain
AIIGCJOP_03059 8.1e-168 bamB M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AIIGCJOP_03060 1.8e-265 der S GTPase that plays an essential role in the late steps of ribosome biogenesis
AIIGCJOP_03061 7.6e-283 dtpT U Proton-dependent permease that transports di- and tripeptides
AIIGCJOP_03062 3.5e-159 S Protein involved in oxidoreductase activity
AIIGCJOP_03063 1.1e-33 yfgJ S zinc-ribbons
AIIGCJOP_03064 1.7e-49
AIIGCJOP_03065 2.2e-185 prt1 E Zinc metalloprotease (Elastase)
AIIGCJOP_03066 1.2e-147 EGP Major facilitator Superfamily
AIIGCJOP_03067 5.3e-195 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AIIGCJOP_03068 1.2e-266 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AIIGCJOP_03069 1.3e-309 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AIIGCJOP_03070 8.3e-118 S Alpha/beta hydrolase family
AIIGCJOP_03071 2.9e-30 S Protein of unknown function (DUF1471)
AIIGCJOP_03072 2.5e-80
AIIGCJOP_03073 3.4e-116 IQ reductase
AIIGCJOP_03074 1.3e-186 P Major facilitator superfamily
AIIGCJOP_03075 3.6e-136 cysL_1 K transcriptional regulator
AIIGCJOP_03076 0.0 yfgF T phosphodiesterase
AIIGCJOP_03077 5.6e-270 ppx 3.6.1.11, 3.6.1.40 FP Belongs to the GppA Ppx family
AIIGCJOP_03078 0.0 ppk 2.7.4.1 H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AIIGCJOP_03079 3.4e-112 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AIIGCJOP_03080 4.1e-192 purM 6.3.3.1, 6.3.4.13 F AIR synthase related protein, N-terminal domain
AIIGCJOP_03081 1.9e-288 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AIIGCJOP_03082 1.4e-110 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AIIGCJOP_03083 2.4e-226 uraA F Xanthine uracil
AIIGCJOP_03084 2e-126 hda L Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA
AIIGCJOP_03085 3.2e-51 arsC 1.20.4.1 P arsenate reductase
AIIGCJOP_03086 4.5e-261 bepA S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state
AIIGCJOP_03087 3.7e-172 perM S permease
AIIGCJOP_03088 1.5e-85 bcp 1.11.1.15 O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AIIGCJOP_03089 3.8e-99 gcvR E glycine cleavage system
AIIGCJOP_03090 5.8e-163 dapA 2.5.1.72, 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AIIGCJOP_03091 4.7e-180 bamC M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AIIGCJOP_03092 7.4e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AIIGCJOP_03093 9.5e-142 ypfJ S Putative neutral zinc metallopeptidase
AIIGCJOP_03094 0.0 tmcA 2.3.1.193, 2.3.1.57 J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)
AIIGCJOP_03095 4.8e-120 ypfH S Phospholipase Carboxylesterase
AIIGCJOP_03096 2.3e-30 ypfN S Uncharacterised protein family (UPF0370)
AIIGCJOP_03097 9.6e-219 dapE 3.5.1.18 E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AIIGCJOP_03098 9.9e-61 yffB 1.20.4.1 P Belongs to the ArsC family
AIIGCJOP_03099 0.0 acrD V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AIIGCJOP_03100 1.8e-269 narQ 2.7.13.3 T Histidine kinase
AIIGCJOP_03101 0.0 gltD 1.4.1.13, 1.4.1.14 C Glutamate synthase
AIIGCJOP_03102 1.1e-96 nudK 3.6.1.13 L GDP-mannose pyrophosphatase
AIIGCJOP_03103 4.2e-184 ypfG S Protein of unknown function (DUF1176)
AIIGCJOP_03104 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AIIGCJOP_03105 5.9e-169 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AIIGCJOP_03106 0.0 maeB 1.1.1.38, 1.1.1.40, 2.3.1.8 C Malic enzyme
AIIGCJOP_03107 1.7e-170 hemF 1.3.3.3 H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX
AIIGCJOP_03108 1.7e-154 amiA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AIIGCJOP_03109 6.9e-77 ypeA K Belongs to the acetyltransferase family. YpeA subfamily
AIIGCJOP_03110 2.9e-73 yfeZ S Protein of unknown function (DUF2919)
AIIGCJOP_03111 1.5e-95 yfeY S Protein of unknown function (DUF1131)
AIIGCJOP_03112 1.8e-167 yfeX P peroxidase
AIIGCJOP_03113 7.2e-189 cysP P Thiosulfate transporter subunit
AIIGCJOP_03114 1.4e-145 cysT P sulfate ABC transporter
AIIGCJOP_03115 6.2e-157 cysW P (ABC) transporter
AIIGCJOP_03116 3.1e-206 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AIIGCJOP_03117 1.2e-163 cysM 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AIIGCJOP_03118 3.7e-143 pdxK 2.7.1.35 H Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AIIGCJOP_03119 4.3e-86 crr G pts system
AIIGCJOP_03120 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AIIGCJOP_03121 1.1e-37 ptsH 2.7.1.121, 2.7.1.202 G PTS HPr component phosphorylation site
AIIGCJOP_03122 5.1e-176 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AIIGCJOP_03123 2e-143 cysZ U High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AIIGCJOP_03124 1e-110 zipA D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins
AIIGCJOP_03125 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AIIGCJOP_03126 6.9e-33 ypeB 2.7.7.7 S protein conserved in bacteria
AIIGCJOP_03127 9.5e-170 yfeH S Bile acid sodium symporter
AIIGCJOP_03128 4.5e-153 yfeR K transcriptional regulator
AIIGCJOP_03134 7.2e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AIIGCJOP_03135 1.2e-51 yfeD L Putative transcription regulator (DUF1323)
AIIGCJOP_03136 4.2e-51 yfeC L Negative Regulator
AIIGCJOP_03139 0.0 yfeA T cyclic-guanylate-specific phosphodiesterase activity
AIIGCJOP_03140 1.4e-196 nupC P Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AIIGCJOP_03141 3.8e-208 mntH P H( )-stimulated, divalent metal cation uptake system
AIIGCJOP_03142 1.5e-24 ypeC S Protein of unknown function (DUF2502)
AIIGCJOP_03143 2e-180 yghZ C reductase
AIIGCJOP_03144 1.5e-308 ipdC 4.1.1.74 GH Belongs to the TPP enzyme family
AIIGCJOP_03145 1.2e-201 yfeO P ion-transport protein
AIIGCJOP_03146 2.1e-182 glk 2.7.1.2 F Belongs to the bacterial glucokinase family
AIIGCJOP_03147 1.9e-127 ypdB K response regulator
AIIGCJOP_03148 1.1e-303 ypdA 2.7.13.3 T Histidine kinase
AIIGCJOP_03149 9.2e-239 yfdZ 2.6.1.83 E aminotransferase
AIIGCJOP_03150 1.3e-157 lpxL 2.3.1.241, 2.3.1.242, 2.3.1.243 M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)
AIIGCJOP_03151 2.7e-221
AIIGCJOP_03153 0.0 murF 3.4.16.4, 6.3.2.10, 6.3.2.29, 6.3.2.30 M Bacterial capsule synthesis protein PGA_cap
AIIGCJOP_03154 1.6e-134 S alpha beta
AIIGCJOP_03155 1.8e-306 M Pfam Methyltransferase
AIIGCJOP_03156 6.7e-114 S Periplasmic Protein
AIIGCJOP_03157 0.0 lapD T GGDEF domain
AIIGCJOP_03158 4.7e-52 S Tryptophan synthase subunit beta
AIIGCJOP_03160 7.3e-191 3.4.21.10 Q calcium- and calmodulin-responsive adenylate cyclase activity
AIIGCJOP_03161 1.5e-234 aggA MU type I secretion outer membrane protein, TolC
AIIGCJOP_03162 0.0 lapB V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AIIGCJOP_03163 1.7e-206 lapC M Type I secretion membrane fusion protein, HlyD
AIIGCJOP_03164 4.6e-70 yaiL S Uncharacterized protein conserved in bacteria (DUF2058)
AIIGCJOP_03165 1.8e-69 3.5.1.19 Q Isochorismatase family
AIIGCJOP_03166 5.7e-155 fliC1 N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AIIGCJOP_03169 2.5e-151 yfdC P Formate nitrite
AIIGCJOP_03170 1.5e-143 vacJ M Lipoprotein
AIIGCJOP_03171 3e-256 fadL I long-chain fatty acid transport protein
AIIGCJOP_03172 2e-40 yfcZ S protein conserved in bacteria
AIIGCJOP_03173 5e-235 fadI 2.3.1.16 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
AIIGCJOP_03174 0.0 fadJ 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate
AIIGCJOP_03175 7.9e-64 sixA T phosphohistidine phosphatase
AIIGCJOP_03176 2.4e-98 yfcN S Belongs to the UPF0115 family
AIIGCJOP_03177 5.9e-182 prmB 2.1.1.297, 2.1.1.298 J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue
AIIGCJOP_03178 3.9e-201 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AIIGCJOP_03179 8.8e-153 mepA M Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AIIGCJOP_03180 5.1e-134 yfcA S membrane transporter protein
AIIGCJOP_03181 7.7e-105 yfcM S protein conserved in bacteria
AIIGCJOP_03182 3.1e-41 yfcL S YfcL protein
AIIGCJOP_03183 0.0 mnmC 2.1.1.61, 2.1.1.72, 2.4.2.29, 4.2.1.151 J Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AIIGCJOP_03184 5.3e-223 fabB 2.3.1.41 H Belongs to the beta-ketoacyl-ACP synthases family
AIIGCJOP_03185 3.1e-204 yfcJ EGP Major facilitator Superfamily
AIIGCJOP_03186 9.9e-167 flk N Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar- associated type III secretion
AIIGCJOP_03187 5e-207 pdxB 1.1.1.290 H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
AIIGCJOP_03188 1.7e-174 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AIIGCJOP_03189 3.9e-153 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AIIGCJOP_03190 1.7e-114 dedA I Pfam SNARE associated Golgi protein
AIIGCJOP_03191 9.9e-166 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AIIGCJOP_03192 1e-229 folC 6.3.2.12, 6.3.2.17 H Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives
AIIGCJOP_03193 5.1e-93 dedD D Non-essential cell division protein that could be required for efficient cell constriction
AIIGCJOP_03194 9.7e-83 cvpA S Colicin v production
AIIGCJOP_03195 9.7e-291 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AIIGCJOP_03196 3e-96 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
AIIGCJOP_03197 3.1e-139 argT ET belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_03198 1.2e-140 hisJ ET belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_03199 3.5e-115 hisQ P (ABC) transporter
AIIGCJOP_03200 2.8e-123 hisM P polar amino acid ABC transporter, inner membrane subunit
AIIGCJOP_03201 1.8e-136 hisP 3.6.3.21 E abc transporter atp-binding protein
AIIGCJOP_03202 2.5e-81 J PFAM GCN5-related N-acetyltransferase
AIIGCJOP_03203 1.3e-162 yfcH CH epimerase
AIIGCJOP_03204 3.4e-56 folX 1.13.11.81, 4.1.2.25, 5.1.99.7, 5.1.99.8 H Dihydroneopterin aldolase
AIIGCJOP_03205 1.6e-101 yfcG O Belongs to the GST superfamily
AIIGCJOP_03206 1.7e-106 yfcF 2.5.1.18 O Glutathione S-transferase
AIIGCJOP_03207 9.2e-98 yfcE S Phosphoesterase
AIIGCJOP_03208 1.3e-91 yfcD L Nudix hydrolase
AIIGCJOP_03209 0.0 pta 1.1.1.40, 2.3.1.8 C belongs to the CobB CobQ family
AIIGCJOP_03210 8.7e-226 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AIIGCJOP_03211 1.9e-80 yfbV S UPF0208 membrane protein
AIIGCJOP_03212 1.4e-89 yfbU S Belongs to the UPF0304 family
AIIGCJOP_03213 9e-108 yfbT 3.1.3.23 S Phosphatase
AIIGCJOP_03214 0.0 yfbS P COG0471 Di- and tricarboxylate transporters
AIIGCJOP_03215 6e-103 yfbR 3.1.3.89 S Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AIIGCJOP_03216 1.1e-236 alaA 2.6.1.2, 2.6.1.66 E in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor'
AIIGCJOP_03217 1.1e-162 lrhA K Transcriptional regulator
AIIGCJOP_03218 1.5e-74 nuoA 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AIIGCJOP_03219 4.2e-129 nuoB 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AIIGCJOP_03220 0.0 nuoC 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AIIGCJOP_03221 6.2e-93 nuoE 1.6.5.3 C PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AIIGCJOP_03222 1.3e-267 nuoF 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AIIGCJOP_03223 0.0 nuoG 1.6.5.3 C NADH-quinone oxidoreductase
AIIGCJOP_03224 6.2e-182 nuoH 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AIIGCJOP_03225 6.5e-88 nuoI 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AIIGCJOP_03226 6.6e-88 nuoJ 1.6.5.3 C Belongs to the complex I subunit 6 family
AIIGCJOP_03227 2.5e-28 nuoK 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AIIGCJOP_03228 0.0 nuoL 1.6.5.3 CP NADH ubiquinone
AIIGCJOP_03229 1e-284 nuoM 1.6.5.3 C NADH ubiquinone oxidoreductase subunit
AIIGCJOP_03230 7.7e-261 nuoN 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AIIGCJOP_03231 1.5e-175 cheV 2.7.13.3 T Two component signalling adaptor domain
AIIGCJOP_03232 1.4e-162 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AIIGCJOP_03233 5.2e-78 elaA S Acyltransferase
AIIGCJOP_03234 7.7e-46 elaB S ribosome binding
AIIGCJOP_03235 1.9e-210 menF 5.4.4.2 H Catalyzes the conversion of chorismate to isochorismate
AIIGCJOP_03236 5.6e-308 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AIIGCJOP_03237 1.9e-109 menH 4.2.99.20 H Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
AIIGCJOP_03238 9.4e-166 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AIIGCJOP_03239 4.6e-177 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
AIIGCJOP_03240 2.6e-263 menE 4.2.1.113, 6.2.1.26 IQ TIGRFAM O-succinylbenzoate-CoA ligase
AIIGCJOP_03241 3.8e-247 tctA S Tripartite tricarboxylate transporter TctA
AIIGCJOP_03242 7e-77 tctB S Tripartite tricarboxylate transporter TctB family
AIIGCJOP_03243 5.7e-183 tctC S Tripartite tricarboxylate transporter family receptor
AIIGCJOP_03244 1.7e-122 T Transcriptional
AIIGCJOP_03245 3.5e-242 tctE 2.7.13.3 T Two-component sensor kinase N-terminal
AIIGCJOP_03246 1.2e-94 yfaZ S YfaZ precursor
AIIGCJOP_03247 1.7e-205 cinA 3.5.1.42 S Belongs to the CinA family
AIIGCJOP_03248 3.6e-232 glpC 1.1.5.3 C Dehydrogenase
AIIGCJOP_03249 9.4e-220 glpB 1.1.5.3 C Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AIIGCJOP_03250 4.5e-311 glpA 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AIIGCJOP_03251 2.5e-258 glpT G transporter
AIIGCJOP_03252 3.2e-200 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AIIGCJOP_03253 5.6e-42 yfaE C Ferredoxin
AIIGCJOP_03254 8.4e-215 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AIIGCJOP_03255 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AIIGCJOP_03256 3.4e-132 ubiG 2.1.1.222, 2.1.1.64 H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway
AIIGCJOP_03257 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AIIGCJOP_03258 0.0 rcsC 2.7.13.3 T PhoQ Sensor
AIIGCJOP_03259 4.8e-114 rcsB K Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions
AIIGCJOP_03260 0.0 rcsD 2.7.13.3, 4.6.1.1 T PhoQ Sensor
AIIGCJOP_03261 3.2e-198 ompC M Belongs to the Gram-negative porin family
AIIGCJOP_03262 4.5e-186 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AIIGCJOP_03263 7e-179 ada 2.1.1.63, 3.2.2.21 FL Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AIIGCJOP_03264 8.3e-114 alkB 1.14.11.33 L Alkylated DNA repair protein
AIIGCJOP_03265 3.8e-301 yojI PQ Cyclic peptide transporter
AIIGCJOP_03266 6.7e-249 mgtE P Acts as a magnesium transporter
AIIGCJOP_03267 1.6e-192 P COG0659 Sulfate permease and related transporters (MFS superfamily)
AIIGCJOP_03268 6e-286 mqo 1.1.5.4 C malate quinone oxidoreductase
AIIGCJOP_03269 6.1e-77 eco M General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases
AIIGCJOP_03270 1.2e-36 ynaJ S Protein of unknown function (DUF2534)
AIIGCJOP_03271 3.3e-201 yajR_1 EGP Major facilitator Superfamily
AIIGCJOP_03272 1.2e-255 S Domain of unknown function (DUF1996)
AIIGCJOP_03273 1.4e-66 NU Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
AIIGCJOP_03274 1e-168 S Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Tip pilus adhesin, which is required for assembly of EcpA into fibers (By similarity)
AIIGCJOP_03275 0.0 NU Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
AIIGCJOP_03276 5.4e-84 matC M Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
AIIGCJOP_03277 2e-66 matB S Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Major subunit of the fimbria
AIIGCJOP_03279 0.0 yejM S Hydrolase of alkaline phosphatase superfamily
AIIGCJOP_03280 6.2e-32 yejL S Belongs to the UPF0352 family
AIIGCJOP_03281 7.1e-181 ndpA S Nucleoid-associated protein
AIIGCJOP_03282 1.8e-44 rplY J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AIIGCJOP_03283 0.0 yejH L Type III restriction protein res subunit
AIIGCJOP_03284 1.5e-129 rsuA 5.4.99.19, 5.4.99.20, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AIIGCJOP_03285 2e-206 bcr EGP Major facilitator Superfamily
AIIGCJOP_03286 6.6e-54 yejG S YejG-like protein
AIIGCJOP_03287 1.8e-279 yejF P ATPase activity
AIIGCJOP_03288 3.1e-163 yejE P ABC transporter (Permease
AIIGCJOP_03289 1.4e-198 yejB P ABC transporter (permease)
AIIGCJOP_03290 0.0 yejA E ABC-type oligopeptide transport system, periplasmic component
AIIGCJOP_03291 7.6e-262 rtn T Involved in resistance to the phages N4 and lambda
AIIGCJOP_03292 4.6e-92 spr 3.4.17.13 M NlpC/P60 family
AIIGCJOP_03293 8.1e-118 lpxT 2.7.4.29 I Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P)
AIIGCJOP_03294 6.5e-179 yeiR S cobalamin synthesis protein, P47K
AIIGCJOP_03295 2e-272 mtlK 1.1.1.11, 1.1.1.17, 1.1.1.289, 1.1.1.57, 1.1.1.58, 1.1.1.67, 2.7.1.17 G Belongs to the mannitol dehydrogenase family
AIIGCJOP_03296 7.7e-227 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
AIIGCJOP_03297 2.9e-102 efp J Elongation factor P
AIIGCJOP_03298 7.8e-31 yeiW S Putative zinc- or iron-chelating domain
AIIGCJOP_03299 3.5e-203 setB EGP Major facilitator Superfamily
AIIGCJOP_03300 1.4e-196 fruB 2.7.1.121, 2.7.1.202, 2.7.3.9 G Bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AIIGCJOP_03301 2.4e-175 fruK 2.7.1.11, 2.7.1.56 H belongs to the carbohydrate kinase PfkB family
AIIGCJOP_03302 3.1e-269 fruA 2.7.1.202 G protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AIIGCJOP_03303 1.1e-132 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pseudouridine kinase activity
AIIGCJOP_03304 4.8e-147 psuG 4.2.1.70 Q Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway
AIIGCJOP_03305 4e-189 yeiM F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AIIGCJOP_03306 1.5e-152 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G PfkB domain protein
AIIGCJOP_03307 2.2e-151 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AIIGCJOP_03308 1.1e-176 yeiH S Belongs to the UPF0324 family
AIIGCJOP_03309 1.4e-156 yeiE K transcriptional regulator
AIIGCJOP_03310 1.3e-271 lysP E amino acid
AIIGCJOP_03311 0.0 cirA P receptor
AIIGCJOP_03312 6.6e-156 yeiG 3.1.2.12 CE1 S Serine hydrolase involved in the detoxification of formaldehyde
AIIGCJOP_03313 2.5e-198 yjiJ EGP Major facilitator Superfamily
AIIGCJOP_03314 1.7e-114 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase
AIIGCJOP_03315 5.4e-209 yeiB S Membrane
AIIGCJOP_03316 1.7e-182 galS K transcriptional regulator
AIIGCJOP_03317 3.7e-182 mglB G Wtih MglAC is involved in the transport of beta-methylgalactoside
AIIGCJOP_03318 1.1e-286 mglA 3.6.3.17 P import. Responsible for energy coupling to the transport system
AIIGCJOP_03319 2.1e-172 mglC P Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_03320 5.5e-127 sanA S Vancomycin high temperature exclusion protein
AIIGCJOP_03321 2.4e-156 cdd 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AIIGCJOP_03322 1.2e-113 yohK M effector of murein hydrolase
AIIGCJOP_03323 1.5e-44 lrgA S UPF0299 membrane protein
AIIGCJOP_03324 1.7e-168 dusC J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs
AIIGCJOP_03325 1.1e-222 mdtQ MU RND efflux system, outer membrane lipoprotein
AIIGCJOP_03326 1.5e-138 IQ oxidoreductase
AIIGCJOP_03327 1.3e-94 yohD S Membrane
AIIGCJOP_03328 1.2e-15
AIIGCJOP_03329 8.3e-105 yohC S Membrane
AIIGCJOP_03330 4.8e-160 pbpG 3.4.16.4, 6.3.2.10 M Belongs to the peptidase S11 family
AIIGCJOP_03331 4.1e-98 pat 2.3.1.183 M N-acetyltransferase
AIIGCJOP_03332 0.0 dld 1.1.5.12 C Catalyzes the oxidation of D-lactate to pyruvate
AIIGCJOP_03333 0.0 bglX 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
AIIGCJOP_03334 1.3e-190 G Belongs to the glycosyl hydrolase 28 family
AIIGCJOP_03335 1.6e-264 G MFS/sugar transport protein
AIIGCJOP_03336 2.3e-205 csbX EGP Major facilitator superfamily
AIIGCJOP_03337 2.5e-164 yehZ M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AIIGCJOP_03338 1.8e-167 yehY P permease
AIIGCJOP_03339 7.8e-158 yehX E abc transporter atp-binding protein
AIIGCJOP_03340 7.2e-114 yehW P permease
AIIGCJOP_03341 6.3e-09 yohO S UPF0387 membrane protein YohO
AIIGCJOP_03342 7.3e-135 mlrA K Transcriptional regulator
AIIGCJOP_03343 2.7e-286 yehU 2.7.13.3 T Histidine kinase
AIIGCJOP_03344 7.4e-124 yehT KT Response regulator of the LytR AlgR family
AIIGCJOP_03345 3e-81 yehS S Protein of unknown function (DUF1456)
AIIGCJOP_03346 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AIIGCJOP_03347 3.3e-203 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
AIIGCJOP_03348 9.9e-55 yohN D response to cobalt ion
AIIGCJOP_03349 1.6e-149 comEA M polysaccharide export
AIIGCJOP_03350 4.9e-68 etp 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AIIGCJOP_03351 6.7e-301 wzc D protein involved in exopolysaccharide biosynthesis
AIIGCJOP_03352 4.2e-267 ddc 2.6.1.76, 4.1.1.86 E decarboxylase
AIIGCJOP_03353 7e-264 dat 2.6.1.76 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AIIGCJOP_03354 5.8e-45
AIIGCJOP_03355 1e-169 S PAAR repeat-containing protein
AIIGCJOP_03356 3.6e-58 S PAAR repeat-containing protein
AIIGCJOP_03357 0.0 IQ Belongs to the beta-ketoacyl-ACP synthases family
AIIGCJOP_03358 5.8e-161 2.3.1.179 H Belongs to the beta-ketoacyl-ACP synthases family
AIIGCJOP_03359 3.2e-122
AIIGCJOP_03360 1.6e-107 V ATPases associated with a variety of cellular activities
AIIGCJOP_03361 3.5e-56
AIIGCJOP_03362 4.6e-196 lolE_2 M MacB-like periplasmic core domain
AIIGCJOP_03363 7.4e-117 M Outer membrane lipoprotein-sorting protein
AIIGCJOP_03364 7.8e-162
AIIGCJOP_03365 1.7e-128 fabD 2.3.1.39 I Acyl transferase domain
AIIGCJOP_03366 1.5e-91 ycdU
AIIGCJOP_03368 5.5e-111 yqgA S Membrane
AIIGCJOP_03369 0.0 speC 4.1.1.17, 4.1.1.18, 4.1.1.19 E decarboxylase
AIIGCJOP_03370 1.4e-226 nupG G Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force
AIIGCJOP_03371 1.3e-199 mltC GH23 M Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AIIGCJOP_03372 7.6e-45 yggX CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AIIGCJOP_03373 6.2e-204 mutY L a g-specific adenine glycosylase
AIIGCJOP_03374 5.9e-137 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AIIGCJOP_03375 2.2e-54 yggL S protein conserved in bacteria
AIIGCJOP_03376 3.3e-124 yggN S Protein of unknown function (DUF2884)
AIIGCJOP_03377 6.3e-206 G Tripartite ATP-independent periplasmic transporter, DctM component
AIIGCJOP_03378 1.5e-59 G TRAP-type C4-dicarboxylate transport system small permease component
AIIGCJOP_03379 3.4e-151 G Bacterial extracellular solute-binding protein, family 7
AIIGCJOP_03380 5.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
AIIGCJOP_03381 1.3e-102 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AIIGCJOP_03382 1.2e-46 yggU S Belongs to the UPF0235 family
AIIGCJOP_03383 2.9e-91 yggT S integral membrane protein
AIIGCJOP_03384 2.2e-120 yggS E Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AIIGCJOP_03385 1.8e-149 yggR NU PFAM Type II secretion system protein E
AIIGCJOP_03386 1.6e-118 K Transcriptional regulator
AIIGCJOP_03387 1.1e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AIIGCJOP_03388 5.5e-98 yqgE K Belongs to the UPF0301 (AlgH) family
AIIGCJOP_03389 1.3e-179 gshB 6.3.2.2, 6.3.2.3 H Belongs to the prokaryotic GSH synthase family
AIIGCJOP_03390 3.5e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AIIGCJOP_03391 3.4e-121 endA 3.1.21.1 L endonuclease I
AIIGCJOP_03392 1e-81 sprT S Belongs to the SprT family
AIIGCJOP_03393 7.4e-253 galP EGP Major facilitator Superfamily
AIIGCJOP_03394 1.4e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AIIGCJOP_03395 0.0 speA 4.1.1.19 H Catalyzes the biosynthesis of agmatine from arginine
AIIGCJOP_03397 1.1e-217 3.2.1.139 G Belongs to the glycosyl hydrolase 67 family
AIIGCJOP_03398 8.5e-218 4.2.2.6 U Oligogalacturonate lyase
AIIGCJOP_03399 1.5e-223 G ABC transporter substrate-binding protein
AIIGCJOP_03400 1.7e-124 G isomerase activity
AIIGCJOP_03401 8.8e-178 speB 3.5.3.11 F Catalyzes the formation of putrescine from agmatine
AIIGCJOP_03402 4.5e-206 EGP Major Facilitator Superfamily
AIIGCJOP_03403 3.8e-59 ndoA 1.7.1.15 C Rieske [2Fe-2S] domain
AIIGCJOP_03404 2.3e-50
AIIGCJOP_03405 4.2e-205 carAa P Rieske [2Fe-2S] domain
AIIGCJOP_03406 1.5e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AIIGCJOP_03407 6e-143 K helix_turn_helix isocitrate lyase regulation
AIIGCJOP_03408 3.4e-177 todE C Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AIIGCJOP_03409 3.5e-211 andAa 1.18.1.3, 1.7.1.15 P Pyridine nucleotide-disulphide oxidoreductase
AIIGCJOP_03410 7.4e-228 sauU G Major Facilitator Superfamily
AIIGCJOP_03411 8e-99 G WxcM-like, C-terminal
AIIGCJOP_03412 1.9e-133 I Alpha/beta hydrolase family
AIIGCJOP_03413 1.6e-140 IQ KR domain
AIIGCJOP_03414 1.3e-126 nadX 1.4.1.21 H Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate
AIIGCJOP_03415 2.7e-269 aldA 1.2.1.3, 1.2.1.8 C Aldehyde dehydrogenase family
AIIGCJOP_03416 3.8e-293 2.2.1.6, 4.1.1.75 C Thiamine pyrophosphate enzyme, central domain
AIIGCJOP_03417 3.4e-127 yggG O metalloprotease
AIIGCJOP_03418 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AIIGCJOP_03419 1.7e-190 epd 1.2.1.12, 1.2.1.72 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AIIGCJOP_03420 8.4e-210 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AIIGCJOP_03421 4.7e-207 fbaA 4.1.2.13 G Aldolase
AIIGCJOP_03422 2e-128 mscS M Mechanosensitive Ion channel
AIIGCJOP_03423 5.1e-108 argO S Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine
AIIGCJOP_03424 1.8e-118 yggE S Oxidative stress defense protein
AIIGCJOP_03425 2.6e-166 argP K Controls the transcription of genes involved in arginine and lysine metabolism
AIIGCJOP_03426 3e-122 rpiA 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AIIGCJOP_03427 9.5e-228 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AIIGCJOP_03428 9e-86 fthC 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AIIGCJOP_03429 8.6e-43 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AIIGCJOP_03430 1.8e-104 ygfB S Belongs to the UPF0149 family
AIIGCJOP_03431 5e-243 pepP 3.4.11.9 E aminopeptidase
AIIGCJOP_03432 4.4e-214 ubiH CH hydroxylase
AIIGCJOP_03433 4e-223 visC CH ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6
AIIGCJOP_03434 1.2e-202 gcvT 2.1.2.10 H The glycine cleavage system catalyzes the degradation of glycine
AIIGCJOP_03435 5.2e-63 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
AIIGCJOP_03436 0.0 gcvP 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AIIGCJOP_03437 6.3e-126 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
AIIGCJOP_03438 5.7e-293 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AIIGCJOP_03439 1.9e-130 ybbH_1 K transcriptional regulator
AIIGCJOP_03440 1.1e-47 yqfB S Belongs to the UPF0267 family
AIIGCJOP_03441 1.2e-112 yqfA S hemolysin iii
AIIGCJOP_03442 1.6e-177 ygfZ S Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication
AIIGCJOP_03443 1.6e-42 sdhE 1.3.5.1, 1.3.5.4 S Flavinator of succinate dehydrogenase
AIIGCJOP_03444 3.8e-64 ygfX S Membrane
AIIGCJOP_03445 2.5e-97 fldB C Low-potential electron donor to a number of redox enzymes
AIIGCJOP_03446 2.5e-161 xerD D recombinase XerD
AIIGCJOP_03447 4.9e-128 dsbC 5.3.4.1 O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AIIGCJOP_03448 0.0 recJ L Single-stranded-DNA-specific exonuclease
AIIGCJOP_03449 1.6e-160 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AIIGCJOP_03450 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AIIGCJOP_03451 3e-88 idi 5.3.3.2 I Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AIIGCJOP_03453 8.3e-111 nlpD DM COG0739 Membrane proteins related to metalloendopeptidases
AIIGCJOP_03455 8.6e-84 arcR T Winged helix-turn-helix DNA binding
AIIGCJOP_03456 3.6e-151 ompA M OmpA-like transmembrane domain
AIIGCJOP_03457 2e-25
AIIGCJOP_03458 4.8e-40 yjdI 1.6.3.4 S Divergent 4Fe-4S mono-cluster
AIIGCJOP_03459 1.1e-43 yjdJ S GCN5-related N-acetyl-transferase
AIIGCJOP_03460 2.9e-208 yqeG E transporter
AIIGCJOP_03461 3.6e-71 YPO2978 S PFAM transmembrane pair domain protein
AIIGCJOP_03462 5.1e-151 allS_3 K Transcriptional regulator
AIIGCJOP_03463 5e-82 S protein containing double-stranded beta helix domain
AIIGCJOP_03464 1.9e-209 yqeF 2.3.1.9 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
AIIGCJOP_03465 3.8e-125 lptD M oligogalacturonate-specific porin
AIIGCJOP_03466 1.3e-239 ogl 4.2.2.6 U oligogalacturonate lyase
AIIGCJOP_03467 1.5e-160 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AIIGCJOP_03468 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AIIGCJOP_03469 1.5e-242 araE EGP Major facilitator Superfamily
AIIGCJOP_03470 9.3e-222 ogl 4.2.2.6 U Oligogalacturonate lyase
AIIGCJOP_03471 6.6e-248 yesO G ABC transporter substrate-binding protein
AIIGCJOP_03472 4e-209 ugpC P Belongs to the ABC transporter superfamily
AIIGCJOP_03473 8.4e-165 togN P PFAM binding-protein-dependent transport systems inner membrane component
AIIGCJOP_03474 7.7e-163 ycjO P PFAM binding-protein-dependent transport systems inner membrane component
AIIGCJOP_03475 1e-56 kdgF S PFAM Cupin 2, conserved barrel domain protein
AIIGCJOP_03476 1.5e-121 ygeA 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AIIGCJOP_03477 2.1e-163 lysR K transcriptional regulator
AIIGCJOP_03478 6.9e-234 lysA 2.7.2.4, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AIIGCJOP_03479 4.4e-186 ascG K Transcriptional regulator
AIIGCJOP_03480 4e-240 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AIIGCJOP_03481 4.4e-285 celH 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AIIGCJOP_03482 2.4e-136 uxuR K FCD
AIIGCJOP_03483 8.5e-84 mshD 2.3.1.189 S PFAM GCN5-related N-acetyltransferase
AIIGCJOP_03484 1.8e-187 galR K transcriptional regulator
AIIGCJOP_03485 0.0 aas 2.3.1.40, 6.2.1.20 I Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1
AIIGCJOP_03486 7.4e-185 lplT 2.3.1.40, 6.2.1.20 U Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell
AIIGCJOP_03487 5.8e-194 tas C Aldo keto reductase
AIIGCJOP_03488 7.7e-32 ygdR S (Lipo)protein
AIIGCJOP_03489 6.5e-125 mutH L Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair
AIIGCJOP_03490 6.2e-69 nudH L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage
AIIGCJOP_03491 0.0 ptsP 2.7.3.9 T Belongs to the PEP-utilizing enzyme family
AIIGCJOP_03492 3e-167 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AIIGCJOP_03493 6e-159 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AIIGCJOP_03494 3.4e-77 ppdA NU prepilin peptidase dependent protein A
AIIGCJOP_03495 8.3e-78 ppdB U prepilin peptidase dependent protein
AIIGCJOP_03496 6.1e-48 ygdB S Protein of unknown function (DUF2509)
AIIGCJOP_03497 2.2e-43 ppdC NU Prepilin peptidase dependent protein c
AIIGCJOP_03498 0.0 recC 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AIIGCJOP_03499 0.0 ptrA 3.4.24.55, 3.4.24.56 O Belongs to the peptidase M16 family
AIIGCJOP_03500 0.0 recB 3.1.11.5, 3.6.4.12 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA
AIIGCJOP_03501 0.0 recD 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AIIGCJOP_03502 1.6e-241 argA 2.3.1.1, 2.7.2.8 E Belongs to the acetyltransferase family. ArgA subfamily
AIIGCJOP_03503 5.4e-212 amiC 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AIIGCJOP_03504 5.9e-08
AIIGCJOP_03505 5.9e-08
AIIGCJOP_03506 5.9e-08
AIIGCJOP_03507 7.5e-200 mltA GH102 M Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AIIGCJOP_03508 5.9e-146 ygdL 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
AIIGCJOP_03509 1.4e-69 csdE 2.8.1.7, 4.4.1.16 S cysteine desulfurase, sulfur acceptor subunit CsdE
AIIGCJOP_03510 9e-215 csdA 2.8.1.7, 4.4.1.16 E Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo
AIIGCJOP_03511 3e-34 ygdI S Lipoprotein
AIIGCJOP_03512 6.9e-167 gcvA K transcriptional regulator
AIIGCJOP_03513 6.6e-66 ygdD S Small membrane protein
AIIGCJOP_03514 2.5e-211 rlmM 2.1.1.186 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AIIGCJOP_03515 2.8e-137 xni 2.7.7.7 L Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment
AIIGCJOP_03516 7.7e-255 sdaB 4.3.1.17 E l-serine dehydratase
AIIGCJOP_03517 7.9e-225 sdaC E serine transporter
AIIGCJOP_03518 3.7e-257 ygdH 3.2.2.10 S Rossmann fold nucleotide-binding protein
AIIGCJOP_03519 9.9e-160 queF 1.7.1.13 K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AIIGCJOP_03520 2.9e-88 syd S regulation of protein complex assembly
AIIGCJOP_03521 1.4e-53 yqcC 3.5.1.28, 5.1.3.13, 5.4.99.26 S protein conserved in bacteria
AIIGCJOP_03522 1.1e-139 truC 5.4.99.26 J Pseudouridine synthase
AIIGCJOP_03523 2.7e-79 yqcA C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
AIIGCJOP_03524 1.9e-250 gudP G transporter
AIIGCJOP_03525 6.6e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
AIIGCJOP_03526 7.1e-261 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
AIIGCJOP_03527 2e-200 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AIIGCJOP_03528 0.0 barA 2.7.13.3 T PhoQ Sensor
AIIGCJOP_03529 4.5e-244 rlmD 2.1.1.190 J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA
AIIGCJOP_03530 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AIIGCJOP_03531 1.2e-143 mazG 3.6.1.66, 3.6.1.9 C nucleoside triphosphate pyrophosphohydrolase
AIIGCJOP_03532 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AIIGCJOP_03533 9.9e-236 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AIIGCJOP_03534 5.5e-212 crtX 2.4.1.276 GT1 CG Belongs to the UDP-glycosyltransferase family
AIIGCJOP_03535 7.4e-126 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AIIGCJOP_03536 4.5e-202 norB G Quinolone resistance protein
AIIGCJOP_03537 5.5e-209 3.5.1.32 S amidohydrolase
AIIGCJOP_03538 0.0 K helix_turn_helix, arabinose operon control protein
AIIGCJOP_03539 5.5e-67 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
AIIGCJOP_03540 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AIIGCJOP_03541 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 H Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
AIIGCJOP_03542 2.3e-136 cysH 1.8.4.10, 1.8.4.8 EH Reduction of activated sulfate into sulfite
AIIGCJOP_03543 6e-183 iap N Catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3
AIIGCJOP_03545 1.8e-175 cysD 1.8.4.10, 1.8.4.8, 2.7.7.4 H Sulfate adenylyltransferase subunit 2
AIIGCJOP_03546 1.7e-260 cysN 2.7.1.25, 2.7.7.4 H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
AIIGCJOP_03547 1.7e-105 cysC 2.7.1.25 F Catalyzes the synthesis of activated sulfate
AIIGCJOP_03548 1.9e-47 ygbE S membrane
AIIGCJOP_03549 1.8e-50 ftsB D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AIIGCJOP_03550 4.9e-128 ispD 2.7.7.60 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
AIIGCJOP_03551 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
AIIGCJOP_03552 2.3e-190 truD 5.4.99.27 J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs
AIIGCJOP_03553 1.1e-128 surE 3.1.3.5 S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AIIGCJOP_03554 2.2e-111 pcm 2.1.1.77 J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AIIGCJOP_03555 2.6e-148 nlpD M Lysin motif
AIIGCJOP_03556 2.8e-177 rpoS K RNA polymerase sigma
AIIGCJOP_03557 1.5e-54 S protein conserved in bacteria
AIIGCJOP_03558 7.4e-193 EGP Major Facilitator Superfamily
AIIGCJOP_03559 9.4e-145 ptxR K LysR substrate binding domain
AIIGCJOP_03560 6.4e-64 hosA K helix_turn_helix multiple antibiotic resistance protein
AIIGCJOP_03561 4.4e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C. Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions
AIIGCJOP_03562 1.5e-277 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate and vanillate
AIIGCJOP_03563 2.5e-39 bsdD 4.1.1.61 S 4-hydroxybenzoate decarboxylase
AIIGCJOP_03564 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AIIGCJOP_03565 9e-31 S Toxin SymE, type I toxin-antitoxin system
AIIGCJOP_03566 2.4e-59 ygbA S Nitrous oxide-stimulated promoter
AIIGCJOP_03567 1.4e-67 G COG2513 PEP phosphonomutase and related enzymes
AIIGCJOP_03568 1.1e-142 ada 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AIIGCJOP_03569 1.9e-215 yceL EGP Major facilitator Superfamily
AIIGCJOP_03570 6.4e-134 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
AIIGCJOP_03571 9.3e-160 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AIIGCJOP_03572 3.9e-179 P ABC transporter substrate-binding protein
AIIGCJOP_03574 6.5e-281 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AIIGCJOP_03575 1.4e-254 ascF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Phosphotransferase System
AIIGCJOP_03576 1.1e-178 ascG K Transcriptional regulator
AIIGCJOP_03577 9.9e-297 S bacterial-type RNA polymerase regulatory region sequence-specific DNA binding
AIIGCJOP_03578 4.8e-12
AIIGCJOP_03579 1.5e-200 norW 1.7.1.15 C One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase
AIIGCJOP_03580 5.1e-273 norV 1.6.3.4 C uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
AIIGCJOP_03581 5e-271 norR KT transcriptional regulator
AIIGCJOP_03582 9.9e-164 gutQ 5.3.1.13 M Arabinose 5-phosphate isomerase
AIIGCJOP_03583 7.5e-138 srlR K DeoR C terminal sensor domain
AIIGCJOP_03584 7.7e-53 gutM K Glucitol operon activator
AIIGCJOP_03585 6.4e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_03586 1e-60 srlB 2.7.1.198 G system, glucitol sorbitol-specific
AIIGCJOP_03587 4e-157 srlE 2.7.1.198 G PTS system, glucitol sorbitol-specific, IIBC subunit
AIIGCJOP_03588 1.1e-98 srlA G PTS system glucitol sorbitol-specific
AIIGCJOP_03589 1.5e-208 mltB GH103 M Lytic murein transglycosylase
AIIGCJOP_03590 6.2e-85 ygaD 3.5.1.42 J Belongs to the CinA family
AIIGCJOP_03591 9.7e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AIIGCJOP_03592 1.2e-80 recX 2.4.1.337 GT4 S Modulates RecA activity
AIIGCJOP_03593 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AIIGCJOP_03594 1.5e-23 csrA J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AIIGCJOP_03602 3.1e-101 yqaB S HAD-superfamily hydrolase, subfamily IA, variant 3
AIIGCJOP_03603 3.5e-55 yqaA S SNARE associated Golgi protein
AIIGCJOP_03604 1.5e-291 gshA 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily
AIIGCJOP_03605 4.9e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AIIGCJOP_03606 1.4e-14
AIIGCJOP_03607 1.5e-47 D Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
AIIGCJOP_03608 1.4e-281 emrB EGP Major facilitator Superfamily
AIIGCJOP_03609 1.5e-190 emrA V multidrug resistance efflux pump
AIIGCJOP_03610 3.8e-93 mprA K Transcriptional
AIIGCJOP_03611 7.3e-177 ygaY EGP Major facilitator Superfamily
AIIGCJOP_03612 7e-189 proX E glycine, betaine
AIIGCJOP_03613 1.5e-160 proW P PFAM binding-protein-dependent transport systems inner membrane component
AIIGCJOP_03614 1.3e-218 proV 3.6.3.32 E glycine, betaine
AIIGCJOP_03615 2.1e-174 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AIIGCJOP_03616 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AIIGCJOP_03617 4.6e-70 nrdI F Probably involved in ribonucleotide reductase function
AIIGCJOP_03618 6.2e-30 nrdH O Glutaredoxin-like protein NrdH
AIIGCJOP_03619 5.2e-16 ygaM S ribosome binding
AIIGCJOP_03620 1.4e-59 ygaC S Protein of unknown function (DUF2002)
AIIGCJOP_03621 1.1e-75 alaE U L-alanine exporter AlaE
AIIGCJOP_03622 6.2e-51 stpA S Belongs to the histone-like protein H-NS family
AIIGCJOP_03623 3.2e-23
AIIGCJOP_03624 3.4e-21 yqaE S Proteolipid membrane potential modulator
AIIGCJOP_03625 8.6e-173 yahB K Transcriptional regulator
AIIGCJOP_03626 2.2e-105 yahD L ankyrin repeat
AIIGCJOP_03627 2.9e-274 sucD 6.2.1.5 C CoA-ligase
AIIGCJOP_03628 6.5e-265 yahG C Protein of unknown function (DUF1116)
AIIGCJOP_03629 3.8e-282 Z012_07875 F Psort location CytoplasmicMembrane, score 10.00
AIIGCJOP_03630 5.3e-170 yahI 2.7.2.2 E Belongs to the carbamate kinase family
AIIGCJOP_03631 1.5e-250 yahJ F Amidohydrolase family
AIIGCJOP_03632 4.2e-164 K LysR substrate binding domain
AIIGCJOP_03633 3.2e-237 G Major Facilitator Superfamily
AIIGCJOP_03634 2.8e-126 IQ KR domain
AIIGCJOP_03635 7.1e-158 tktB 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
AIIGCJOP_03636 3.3e-178 2.2.1.1 G Transketolase
AIIGCJOP_03637 1.6e-103 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AIIGCJOP_03638 2.7e-160 K transcriptional regulator
AIIGCJOP_03639 3.9e-96 pagC M Membrane
AIIGCJOP_03640 5.8e-42
AIIGCJOP_03641 8.9e-20
AIIGCJOP_03642 2.9e-28
AIIGCJOP_03643 1.2e-68 S Immunity protein 63
AIIGCJOP_03644 2.8e-49
AIIGCJOP_03645 5.2e-56
AIIGCJOP_03646 1.1e-58
AIIGCJOP_03648 1.9e-45 U domain, Protein
AIIGCJOP_03649 3e-48 S Cell wall assembly protein
AIIGCJOP_03650 2e-28
AIIGCJOP_03651 6.2e-49
AIIGCJOP_03652 3.5e-45
AIIGCJOP_03653 1.4e-87 S Uncharacterized protein conserved in bacteria (DUF2247)
AIIGCJOP_03654 0.0 U Large exoproteins involved in heme utilization or adhesion
AIIGCJOP_03655 4.8e-99 hlyC O RTX toxin acyltransferase
AIIGCJOP_03656 0.0 fhaC U hemolysin activation secretion protein
AIIGCJOP_03657 1.9e-44 ydeI S single-species biofilm formation on inanimate substrate
AIIGCJOP_03658 4.4e-70
AIIGCJOP_03659 1.3e-65 S Protein of unknown function (DUF421)
AIIGCJOP_03660 9.8e-89 cinA 3.5.1.42 S Belongs to the CinA family
AIIGCJOP_03661 1.8e-136 yxnA S Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_03662 2.6e-183 cioB 1.10.3.14 C oxidase subunit
AIIGCJOP_03663 2.2e-265 cioA 1.10.3.14 C oxidase, subunit
AIIGCJOP_03664 2.6e-155 katN P Mn-containing catalase
AIIGCJOP_03665 1.8e-84 yciE S protein conserved in bacteria
AIIGCJOP_03666 1e-79 yciF S protein conserved in bacteria
AIIGCJOP_03668 1.5e-73
AIIGCJOP_03669 6.1e-48 yycE 3.4.21.26, 5.3.1.24 E PFAM Glyoxalase bleomycin resistance protein dioxygenase
AIIGCJOP_03670 3.9e-114 rluA 5.4.99.28, 5.4.99.29 J Pseudouridine synthase
AIIGCJOP_03671 1.1e-183 tetV EGP Major facilitator Superfamily
AIIGCJOP_03672 1.5e-64 S protein conserved in bacteria
AIIGCJOP_03673 1.1e-66 S protein conserved in bacteria
AIIGCJOP_03674 3.1e-162 K transcriptional regulator
AIIGCJOP_03675 9.8e-90
AIIGCJOP_03677 4e-90 K transcriptional Regulator, LysR family
AIIGCJOP_03678 5e-161 hpaX G Major facilitator Superfamily
AIIGCJOP_03679 7.7e-106 4.1.2.17 G Class II aldolase adducin family protein
AIIGCJOP_03680 1e-210 M Type I secretion membrane fusion protein, HlyD
AIIGCJOP_03681 0.0 V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AIIGCJOP_03682 2.1e-247 MU type I secretion outer membrane protein, TolC
AIIGCJOP_03683 0.0 bipA U Bacterial Ig-like domain (group 3)
AIIGCJOP_03684 0.0 bipA NU TIGRFAM Outer membrane protein
AIIGCJOP_03685 4.8e-78 yceI S Belongs to the UPF0312 family
AIIGCJOP_03686 7.2e-108 nanE 2.7.1.60, 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AIIGCJOP_03687 6e-172 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
AIIGCJOP_03688 2.2e-45 S Antibiotic biosynthesis monooxygenase
AIIGCJOP_03689 2.8e-10
AIIGCJOP_03690 1.1e-86 smpB J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AIIGCJOP_03691 4.3e-74 ratA I oligoketide cyclase lipid transport protein
AIIGCJOP_03692 1.5e-38 rnfH S Belongs to the UPF0125 (RnfH) family
AIIGCJOP_03693 9.2e-56 bamE M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AIIGCJOP_03694 1.1e-300 recN L May be involved in recombinational repair of damaged DNA
AIIGCJOP_03695 2e-163 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AIIGCJOP_03696 2.1e-95 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AIIGCJOP_03697 1.3e-213 yfjD P Mg2 and Co2 transporter CorB
AIIGCJOP_03698 1.3e-143 ypjD S Cytochrome c assembly protein
AIIGCJOP_03699 4.4e-234 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components
AIIGCJOP_03700 2.2e-38 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AIIGCJOP_03701 1.8e-98 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AIIGCJOP_03702 1.2e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AIIGCJOP_03703 4.2e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AIIGCJOP_03704 2.9e-61 copB P Protein of unknown function (DUF2946)
AIIGCJOP_03705 1.4e-235 S Iron-regulated membrane protein
AIIGCJOP_03706 5.8e-177 yfiN 2.7.7.65 T Diguanylate cyclase
AIIGCJOP_03707 1.5e-68 yfiR S bacterial-type flagellum-dependent swarming motility
AIIGCJOP_03708 1.8e-57 yfiL S Protein of unknown function (DUF2799)
AIIGCJOP_03709 2.9e-201 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AIIGCJOP_03710 3.5e-205 tyrA 1.3.1.12, 1.3.1.13, 1.3.1.43, 5.4.99.5 E T-protein
AIIGCJOP_03711 3.6e-173 yvrE 3.1.1.15 G gluconolactonase
AIIGCJOP_03712 1.6e-213 pheA 1.3.1.12, 2.3.1.79, 2.5.1.54, 4.2.1.51, 5.4.99.5 E chorismate mutase
AIIGCJOP_03713 1.1e-56 hpf J Sigma 54 modulation protein ribosomal protein S30EA
AIIGCJOP_03714 1.6e-134 bamD GH23 M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AIIGCJOP_03715 1.4e-181 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AIIGCJOP_03716 1.1e-130 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
AIIGCJOP_03717 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AIIGCJOP_03718 7.2e-116 yieP K transcriptional regulator
AIIGCJOP_03719 3.1e-246 hsrA EGP Major facilitator Superfamily
AIIGCJOP_03720 4.5e-180 rbsR K Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression
AIIGCJOP_03721 2.2e-152 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AIIGCJOP_03722 1.3e-154 rbsB G Periplasmic
AIIGCJOP_03723 4.8e-150 rbsC G Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_03724 3.2e-278 rbsA 3.6.3.17 P import. Responsible for energy coupling to the transport system
AIIGCJOP_03725 5.8e-68 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
AIIGCJOP_03726 0.0 kup P transport of potassium into the cell
AIIGCJOP_03727 1.5e-272 ravA S Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone
AIIGCJOP_03728 3.9e-265 viaA S VWA domain protein interacting with AAA ATPase
AIIGCJOP_03729 1.9e-186 asnA 6.3.1.1 E aspartate--ammonia ligase
AIIGCJOP_03730 6.1e-79 asnC K transcriptional
AIIGCJOP_03731 1.6e-79 mioC C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
AIIGCJOP_03732 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AIIGCJOP_03733 1.1e-107 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA
AIIGCJOP_03734 1e-55 atpI C Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
AIIGCJOP_03735 9.9e-149 atpB C it plays a direct role in the translocation of protons across the membrane
AIIGCJOP_03736 1.7e-32 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AIIGCJOP_03737 2.8e-55 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AIIGCJOP_03738 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AIIGCJOP_03739 3.6e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AIIGCJOP_03740 1.7e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AIIGCJOP_03741 6.8e-259 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AIIGCJOP_03742 1.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AIIGCJOP_03743 0.0 pelX 4.2.2.9 M Parallel beta-helix repeats
AIIGCJOP_03744 1.5e-250 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AIIGCJOP_03745 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AIIGCJOP_03746 1.7e-193 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
AIIGCJOP_03747 2.7e-169 pstC P probably responsible for the translocation of the substrate across the membrane
AIIGCJOP_03748 3.8e-154 pstA P phosphate transport system permease
AIIGCJOP_03749 5.3e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AIIGCJOP_03750 1.2e-129 phoU P Plays a role in the regulation of phosphate uptake
AIIGCJOP_03751 3.2e-180 yieL P Belongs to the glycosyl hydrolase 13 family
AIIGCJOP_03752 3.6e-123 yieH S HAD-superfamily hydrolase subfamily IA, variant 3
AIIGCJOP_03753 1.8e-227 yieG S PFAM Xanthine uracil vitamin C permease
AIIGCJOP_03754 3.6e-97 yieF S NAD(P)H-dependent FMN reductase
AIIGCJOP_03755 5.7e-119 yieE 2.7.8.7 H Phosphopantetheinyl transferase
AIIGCJOP_03756 3.3e-183 yidZ K Involved in anaerobic NO protection
AIIGCJOP_03757 7.9e-187 mdtL EGP Major facilitator superfamily MFS_1
AIIGCJOP_03758 3.2e-215 tnaB E amino acid
AIIGCJOP_03759 3.2e-272 tnaA 4.1.99.1 E Belongs to the beta-eliminating lyase family
AIIGCJOP_03760 8.3e-249 mnmE J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AIIGCJOP_03761 8.6e-293 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
AIIGCJOP_03762 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AIIGCJOP_03763 5e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AIIGCJOP_03764 5.9e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AIIGCJOP_03765 4.7e-199 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AIIGCJOP_03766 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AIIGCJOP_03767 7.6e-141 yidA S HAD-superfamily hydrolase, subfamily IIB
AIIGCJOP_03768 3.9e-122 dgoR K FCD domain
AIIGCJOP_03769 2.6e-155 dgoK 2.7.1.58 G 2-keto-3-deoxy-galactonokinase
AIIGCJOP_03770 2.7e-106 dgoA 4.1.2.14, 4.1.2.21, 4.1.3.42 G KDPG and KHG aldolase
AIIGCJOP_03771 7.7e-224 dgoD 4.2.1.6 H Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate
AIIGCJOP_03772 3.4e-244 dgoT G Major facilitator superfamily
AIIGCJOP_03773 8.3e-224 yidR U Biopolymer transporter Tol
AIIGCJOP_03774 2.9e-46 yidQ S Protein of unknown function (DUF1375)
AIIGCJOP_03775 4.2e-71 ibpA O Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent
AIIGCJOP_03776 5.5e-74 ibpB O Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent
AIIGCJOP_03777 3.9e-293 yidE U transport protein
AIIGCJOP_03778 8.4e-263 P Sulfatase
AIIGCJOP_03779 1.9e-47 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
AIIGCJOP_03780 1.1e-232 S PTS system sugar-specific permease component
AIIGCJOP_03781 3.1e-198 2.8.2.22 S Arylsulfotransferase Ig-like domain
AIIGCJOP_03782 8.8e-54 yidH S Membrane
AIIGCJOP_03783 3.7e-55 yidG S Membrane
AIIGCJOP_03784 5.3e-166 yidF C Anaerobic sulfatase maturase
AIIGCJOP_03785 2.2e-227 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
AIIGCJOP_03786 5.2e-199 emrD EGP Major facilitator Superfamily
AIIGCJOP_03787 4.7e-76 K Acetyltransferase (GNAT) domain
AIIGCJOP_03790 0.0 ilvB 2.2.1.6 H acetolactate synthase
AIIGCJOP_03791 2.9e-47 ilvN 2.2.1.6 E acetolactate synthase
AIIGCJOP_03792 3.3e-101 uhpA K Two component transcriptional regulator, LuxR family
AIIGCJOP_03793 2.4e-273 uhpB 2.7.13.3 T Signal transduction histidine kinase
AIIGCJOP_03794 3.5e-244 uhpC G PFAM Major facilitator superfamily
AIIGCJOP_03795 2.5e-253 uhpT G PFAM Major facilitator superfamily
AIIGCJOP_03796 8.9e-192 mhpC 3.4.11.5 I Alpha beta hydrolase
AIIGCJOP_03797 1.1e-75 yicN S Protein of unknown function (DUF1198)
AIIGCJOP_03798 1.6e-200 nepI EGP Major facilitator Superfamily
AIIGCJOP_03799 2.8e-152 yicL EG transporter
AIIGCJOP_03800 7.5e-266 lamB G Maltoporin (phage lambda and maltose receptor)
AIIGCJOP_03801 6.9e-47 celC 2.7.1.196, 2.7.1.205 G PTS system, cellobiose-specific IIA component
AIIGCJOP_03802 6.4e-281 gmuD 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AIIGCJOP_03803 2.4e-237 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AIIGCJOP_03804 3.1e-50 celA 2.7.1.196, 2.7.1.205 G Phosphotransferase system, lactose cellobiose-specific IIB subunit
AIIGCJOP_03805 8.2e-171 ascG_1 K transcriptional regulator
AIIGCJOP_03806 3.4e-46
AIIGCJOP_03807 1.7e-67 S Acetyltransferase (GNAT) domain
AIIGCJOP_03808 2.8e-109 K Transcriptional regulator
AIIGCJOP_03809 2.1e-266 bmr3 EGP Major facilitator Superfamily
AIIGCJOP_03810 1.7e-137 metQ M Belongs to the nlpA lipoprotein family
AIIGCJOP_03811 3.1e-123 yddR S Beta-lactamase superfamily domain
AIIGCJOP_03812 1.4e-154 adpA K DJ-1/PfpI family
AIIGCJOP_03813 6.9e-198 S AAA ATPase domain
AIIGCJOP_03814 7e-178 ybgA S Conserved Protein
AIIGCJOP_03815 8.2e-67 hiuH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
AIIGCJOP_03816 1.1e-127 K helix_turn_helix, mercury resistance
AIIGCJOP_03817 8.5e-93 blc M Outer Membrane Lipoprotein
AIIGCJOP_03818 8.6e-171
AIIGCJOP_03819 3.2e-42
AIIGCJOP_03820 6.6e-20 proV 3.6.3.32 K sequence-specific DNA binding
AIIGCJOP_03821 2.4e-69 yjaB K Acetyltransferase (GNAT) domain
AIIGCJOP_03822 2.8e-142 ydeC K AraC-like ligand binding domain
AIIGCJOP_03823 0.0 bglB 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
AIIGCJOP_03824 2.7e-215 G transporter
AIIGCJOP_03825 6.8e-44 S Toxin SymE, type I toxin-antitoxin system
AIIGCJOP_03826 1e-24 S protein encoded in hypervariable junctions of pilus gene clusters
AIIGCJOP_03829 2.6e-28 immA E IrrE N-terminal-like domain
AIIGCJOP_03830 1.5e-43 S Beta protein
AIIGCJOP_03831 1.4e-14
AIIGCJOP_03833 1.1e-256 yicJ G COG2211 Na melibiose symporter and related transporters
AIIGCJOP_03834 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
AIIGCJOP_03835 0.0 yicH M AsmA Family
AIIGCJOP_03836 1.8e-243 xanP F xanthine
AIIGCJOP_03837 8.2e-200 gltS P Catalyzes the sodium-dependent transport of glutamate
AIIGCJOP_03838 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AIIGCJOP_03839 8.9e-116 trmH 2.1.1.185, 2.1.1.34 J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA
AIIGCJOP_03840 0.0 spoT 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AIIGCJOP_03841 6.1e-34 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AIIGCJOP_03842 2.4e-110 F Guanylate kinase
AIIGCJOP_03843 4.1e-266 ligB 6.5.1.2 L Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction
AIIGCJOP_03844 1.4e-99 yicG S Membrane
AIIGCJOP_03845 2.6e-115 I Acyltransferase family
AIIGCJOP_03846 9.5e-150 yicC S Stress-induced protein
AIIGCJOP_03847 1e-125 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AIIGCJOP_03848 2e-112 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AIIGCJOP_03849 2.1e-100 slmA D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions
AIIGCJOP_03850 6.1e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
AIIGCJOP_03851 4.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AIIGCJOP_03852 1.4e-105 radC E Belongs to the UPF0758 family
AIIGCJOP_03853 6.6e-37 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AIIGCJOP_03854 1.9e-22 rpmG J there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc
AIIGCJOP_03855 4.3e-152 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AIIGCJOP_03856 1.8e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AIIGCJOP_03857 1.5e-133 waaE GT2 S PFAM Glycosyl transferase, family 2
AIIGCJOP_03858 6.3e-235 kdtA 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 M glycosyl transferase group 1
AIIGCJOP_03859 2.2e-293 Z012_09105 2.7.8.42, 2.7.8.43 S Sulfatase
AIIGCJOP_03860 3.8e-187 M transferase activity, transferring glycosyl groups
AIIGCJOP_03861 2.3e-184 wgaB 2.4.2.53 GT2 M Glycosyl transferase, family 2
AIIGCJOP_03862 5.7e-227 S O-Antigen ligase
AIIGCJOP_03863 7.3e-195 walR GT4 M glycosyl transferase group 1
AIIGCJOP_03864 8e-202 rfaG GT4 M Catalyzes the addition of the first glucose residue to the LPS core
AIIGCJOP_03865 5.2e-209 rfaQ GT9 M heptosyltransferase
AIIGCJOP_03866 6.5e-179 rfaC GT9 M PFAM glycosyl transferase family 9
AIIGCJOP_03867 2.1e-199 rfaF GT9 M heptosyltransferase
AIIGCJOP_03868 1.8e-178 hldD 5.1.3.20 GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose
AIIGCJOP_03869 8.9e-223 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
AIIGCJOP_03870 1.5e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
AIIGCJOP_03871 1.2e-141 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AIIGCJOP_03872 7.3e-164 yibQ S protein conserved in bacteria
AIIGCJOP_03873 2.9e-139 envC D Peptidase family M23
AIIGCJOP_03874 3.5e-288 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AIIGCJOP_03875 3.4e-71 yibN 2.8.1.1, 2.8.1.2 P rhodanese-related sulfurtransferase
AIIGCJOP_03876 7.3e-42 grxC O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AIIGCJOP_03877 3.8e-84 secB U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AIIGCJOP_03878 2.8e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AIIGCJOP_03879 1.1e-150 cysE 2.3.1.30 E serine acetyltransferase
AIIGCJOP_03880 4.2e-83 trmL 2.1.1.207 J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AIIGCJOP_03881 3.7e-221 lldD 1.1.2.3 C Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain
AIIGCJOP_03882 8.2e-129 lldR K FCD
AIIGCJOP_03883 3e-301 lldP C L-lactate permease
AIIGCJOP_03884 2.9e-52 yibL S Protein of unknown function (DUF2810)
AIIGCJOP_03885 3.3e-101 mtlR K Mannitol repressor
AIIGCJOP_03886 6.2e-205 mtlD 1.1.1.17 C Mannitol-1-Phosphate 5-Dehydrogenase
AIIGCJOP_03887 0.0 mtlA 2.7.1.197, 2.7.1.202 G PTS system mannitol-specific
AIIGCJOP_03888 1.2e-58 yibI S Protein of unknown function (DUF3302)
AIIGCJOP_03889 7.2e-198 yibH V secretion protein HlyD family
AIIGCJOP_03890 3.3e-104 yibF 2.5.1.18 O Glutathione S-Transferase
AIIGCJOP_03891 8.2e-228 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
AIIGCJOP_03892 0.0 selB J Translation elongation factor
AIIGCJOP_03893 1.2e-152 GK ROK family
AIIGCJOP_03894 8.3e-298 aldB C belongs to the aldehyde dehydrogenase family
AIIGCJOP_03895 1.5e-156 yiaU K Transcriptional regulator
AIIGCJOP_03896 2.6e-116 yiaT M MltA-interacting protein
AIIGCJOP_03897 0.0 3.2.1.185 GH127 S protein conserved in bacteria
AIIGCJOP_03898 2.6e-258 G COG2211 Na melibiose symporter and related transporters
AIIGCJOP_03899 2.5e-139 yisR K transcriptional regulator
AIIGCJOP_03900 3.8e-76 ysaA C Electron transport protein
AIIGCJOP_03901 5.4e-247 avtA 2.6.1.66 E Valine--pyruvate aminotransferase
AIIGCJOP_03902 0.0 malS 3.2.1.1 GH13 G alpha-amylase
AIIGCJOP_03903 1.1e-101 bax GH73 S FlgJ-related protein
AIIGCJOP_03904 4.8e-221 xylR 5.3.1.12 K transcriptional regulator
AIIGCJOP_03905 8.3e-189 xylH G Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_03906 2.1e-280 xylG 3.6.3.17 P import. Responsible for energy coupling to the transport system
AIIGCJOP_03907 5e-179 xylF G D-xylose ABC transporter periplasmic substrate-binding protein
AIIGCJOP_03908 3e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
AIIGCJOP_03909 2.7e-274 xylB 2.7.1.17, 2.7.1.189, 2.7.1.5 G xylulose kinase
AIIGCJOP_03910 3.5e-68 yiaA S Membrane
AIIGCJOP_03911 2.3e-176 wecH S Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
AIIGCJOP_03912 6.7e-42 ysaB S YsaB-like lipoprotein
AIIGCJOP_03913 1.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AIIGCJOP_03914 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AIIGCJOP_03915 6.3e-272 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
AIIGCJOP_03916 1.8e-44 yiaG K transcriptional regulator
AIIGCJOP_03917 1.6e-123 yiaF S exported protein
AIIGCJOP_03918 4e-33 cspA K Cold shock
AIIGCJOP_03919 1.6e-174 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively
AIIGCJOP_03920 5.4e-242 G Major facilitator superfamily
AIIGCJOP_03921 2.9e-160 kdgK 2.7.1.13, 2.7.1.45 G 2-dehydro-3-deoxygluconokinase
AIIGCJOP_03922 1.5e-122 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
AIIGCJOP_03923 1.7e-182 ptxS K transcriptional regulator
AIIGCJOP_03924 3.4e-83 yiaD M Belongs to the ompA family
AIIGCJOP_03925 0.0 bisC 1.7.2.3, 1.8.5.3 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_03926 7.2e-77 yiaC 2.3.1.1, 2.3.1.210 K acetyltransferase
AIIGCJOP_03927 7.4e-106 tag 3.2.2.20 L glycosylase
AIIGCJOP_03928 2.9e-120 yhjY N outer membrane autotransporter
AIIGCJOP_03930 3.4e-182 yhjX P Major facilitator superfamily
AIIGCJOP_03931 0.0 eptB 2.7.8.42, 2.7.8.43 S membrane-associated metal-dependent hydrolase
AIIGCJOP_03932 1.7e-07
AIIGCJOP_03933 0.0 dppA E Bacterial extracellular solute-binding proteins, family 5 Middle
AIIGCJOP_03934 3.7e-185 dppB P Binding-protein-dependent transport system inner membrane component
AIIGCJOP_03935 1.2e-123 dppC P N-terminal TM domain of oligopeptide transport permease C
AIIGCJOP_03936 3.6e-177 dppD P Belongs to the ABC transporter superfamily
AIIGCJOP_03937 1.1e-189 dppF P Belongs to the ABC transporter superfamily
AIIGCJOP_03938 2.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
AIIGCJOP_03945 3.7e-142 yhdZ 3.6.3.21 E (ABC) transporter
AIIGCJOP_03946 1.6e-202 yhdY P amino acid ABC transporter
AIIGCJOP_03947 3.1e-204 yhdX P amino acid ABC transporter
AIIGCJOP_03948 1.3e-190 aapJ ET Belongs to the bacterial solute-binding protein 3 family
AIIGCJOP_03949 6e-32 yhdV S Protein involved in biological_process
AIIGCJOP_03950 0.0 acrF V Hydrophobe amphiphile efflux-1 HAE1
AIIGCJOP_03951 9.2e-193 acrE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AIIGCJOP_03952 2.9e-87 ttgR K acrEF envCD operon
AIIGCJOP_03953 0.0 gmr 2.7.7.65 T MHYT domain
AIIGCJOP_03954 5.5e-22 yhdU S Protein of unknown function (DUF2556)
AIIGCJOP_03955 4.4e-46 fis K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AIIGCJOP_03956 1.4e-161 dusB H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AIIGCJOP_03957 9.1e-109 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
AIIGCJOP_03958 2.4e-164 prmA J Ribosomal protein L11 methyltransferase
AIIGCJOP_03959 2.7e-237 panF H Sodium:solute symporter family
AIIGCJOP_03960 1.3e-38 yhdT S Membrane
AIIGCJOP_03961 1.4e-256 accC 6.3.4.14, 6.4.1.2 I Biotin carboxylase
AIIGCJOP_03962 1.4e-62 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AIIGCJOP_03963 4.3e-77 aroQ 3.4.13.9, 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
AIIGCJOP_03964 6e-103 msrQ C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AIIGCJOP_03965 8e-193 msrP C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AIIGCJOP_03966 2.7e-177 yhdH C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
AIIGCJOP_03967 0.0 csrD T GGDEF domain
AIIGCJOP_03968 1.3e-190 mreB D rod shape-determining protein MreB
AIIGCJOP_03969 2.2e-177 mreC M Involved in formation and maintenance of cell shape
AIIGCJOP_03970 1.6e-82 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AIIGCJOP_03971 1.2e-100 maf 2.1.1.190 D Maf-like protein
AIIGCJOP_03972 3.6e-274 rng J Involved in the processing of the 5'-end of 16S rRNA
AIIGCJOP_03973 0.0 yhdP D Membrane
AIIGCJOP_03974 4.2e-267 tldD S 'responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase
AIIGCJOP_03975 8.5e-165 aaeR K Transcriptional regulator
AIIGCJOP_03976 2e-29 aaeX S Protein of unknown function (DUF1656)
AIIGCJOP_03977 1.2e-161 aaeA V P-hydroxybenzoic acid efflux pump subunit AaeA
AIIGCJOP_03978 0.0 aaeB U Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell
AIIGCJOP_03979 3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
AIIGCJOP_03980 7.3e-40 yhcO K inhibitor
AIIGCJOP_03981 7.1e-32 bhsA_1 S Protein of unknown function (DUF1471)
AIIGCJOP_03982 6.1e-15 yhcN S Protein of unknown function (DUF1471)
AIIGCJOP_03983 1.5e-77 argR K Regulates arginine biosynthesis genes
AIIGCJOP_03984 7.1e-167 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
AIIGCJOP_03985 2.3e-193 degS 3.4.21.107 O Periplasmic serine protease DegS
AIIGCJOP_03986 3.5e-215 degQ 1.3.1.74, 3.4.21.107 M Belongs to the peptidase S1C family
AIIGCJOP_03987 1.4e-63 yhcB S Cytochrome D ubiquinol oxidase, subunit
AIIGCJOP_03988 1.1e-201 zapE D Reduces the stability of FtsZ polymers in the presence of ATP
AIIGCJOP_03989 3.1e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AIIGCJOP_03990 8.1e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
AIIGCJOP_03991 1e-116 sspA O Belongs to the GST superfamily
AIIGCJOP_03992 9e-81 sspB S stringent starvation protein b
AIIGCJOP_03993 1.5e-277 gltD 1.4.1.13, 1.4.1.14 C Glutamate synthase
AIIGCJOP_03994 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E GXGXG motif
AIIGCJOP_03995 4.1e-170 yhcC S radical SAM protein
AIIGCJOP_03996 8.5e-263 yjgR S Domain of unknown function DUF87
AIIGCJOP_03997 1.7e-277 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
AIIGCJOP_03998 5.1e-195 yjgB 1.1.1.1 S alcohol dehydrogenase
AIIGCJOP_03999 1.1e-78 yjgM K Acetyltransferase
AIIGCJOP_04000 4.4e-65 yjgN S Bacterial protein of unknown function (DUF898)
AIIGCJOP_04001 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AIIGCJOP_04002 9.6e-79 holC 2.7.7.7 L DNA polymerase III chi subunit
AIIGCJOP_04003 3.1e-289 pepA 3.4.11.1, 3.4.11.23 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AIIGCJOP_04004 1.4e-187 lptF S Permease
AIIGCJOP_04005 1.1e-190 lptG S permease
AIIGCJOP_04006 0.0 arcB 2.7.13.3 T PhoQ Sensor
AIIGCJOP_04007 5.4e-105 elbB Q Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AIIGCJOP_04008 6.1e-126 mtgA 2.4.1.129, 3.4.16.4 GT51 M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AIIGCJOP_04009 3e-41 ptsO 2.7.1.121, 2.7.1.202, 2.7.3.9 G Phosphotransferase System
AIIGCJOP_04010 1.2e-157 rapZ S Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS
AIIGCJOP_04011 1.6e-80 ptsN 2.7.1.194, 2.7.1.195, 2.7.1.202, 2.7.3.9 G PTS IIA-like nitrogen-regulatory protein PtsN
AIIGCJOP_04012 4.7e-45 hpf J sigma (54) modulation protein
AIIGCJOP_04013 1.5e-245 rpoN K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AIIGCJOP_04014 2.4e-130 lptB S abc transporter atp-binding protein
AIIGCJOP_04015 2.4e-90 lptA T Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AIIGCJOP_04016 7.3e-98 lptC S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA
AIIGCJOP_04017 8.5e-99 kdsC 3.1.3.45 S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AIIGCJOP_04018 1e-176 kdsD 5.3.1.13 M Arabinose 5-phosphate isomerase
AIIGCJOP_04019 2.6e-164 yrbG P antiporter
AIIGCJOP_04020 1.6e-143 mlaF Q (ABC) transporter
AIIGCJOP_04021 6.6e-134 mlaE Q COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
AIIGCJOP_04022 6.3e-94 mlaD Q ABC-type transport system involved in resistance to organic solvents periplasmic component
AIIGCJOP_04023 2.4e-110 mlaC Q ABC-type transport system involved in resistance to organic solvents auxiliary component
AIIGCJOP_04024 6.7e-31 mlaB S NTP binding protein (Contains STAS domain)
AIIGCJOP_04025 3.1e-40 yrbA K Belongs to the BolA IbaG family
AIIGCJOP_04026 7.7e-233 murA 2.5.1.7 M Belongs to the EPSP synthase family. MurA subfamily
AIIGCJOP_04027 1.8e-44 sfsB K transcriptional regulator
AIIGCJOP_04028 6.2e-174 ispB 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AIIGCJOP_04029 8.1e-51 rplU J This protein binds to 23S rRNA in the presence of protein L20
AIIGCJOP_04030 3.7e-41 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AIIGCJOP_04031 2.1e-169 yhbE EG EamA-like transporter family
AIIGCJOP_04032 1e-199 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AIIGCJOP_04033 2.1e-172 T PhoQ Sensor
AIIGCJOP_04034 4.5e-115 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_04035 4e-254 dacB 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
AIIGCJOP_04036 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AIIGCJOP_04037 9.3e-53 yhbY J RNA-binding protein containing KH domain possibly ribosomal protein
AIIGCJOP_04038 2e-112 ftsJ 2.1.1.166 J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AIIGCJOP_04039 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AIIGCJOP_04040 5.5e-150 folP 2.5.1.15 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AIIGCJOP_04041 1.1e-248 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AIIGCJOP_04042 1.3e-46 secG U Preprotein translocase, subunit SecG
AIIGCJOP_04044 4.4e-263 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type
AIIGCJOP_04045 5.9e-08
AIIGCJOP_04046 1.4e-81 rimP J Required for maturation of 30S ribosomal subunits
AIIGCJOP_04047 2.4e-270 nusA K Participates in both transcription termination and antitermination
AIIGCJOP_04048 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AIIGCJOP_04049 1.2e-62 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AIIGCJOP_04050 1.8e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AIIGCJOP_04051 1.9e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AIIGCJOP_04053 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AIIGCJOP_04054 1.3e-162 nlpI S May be involved in cell division
AIIGCJOP_04055 3.9e-281 deaD 3.6.4.13 F DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation
AIIGCJOP_04056 3.4e-225 mtr E amino acid
AIIGCJOP_04057 2.4e-189 yhbW C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AIIGCJOP_04058 5.8e-163 yhbV O protease
AIIGCJOP_04059 8.9e-184 yhbU O Peptidase U32
AIIGCJOP_04060 6.3e-88 yhbT I lipid carrier protein
AIIGCJOP_04061 1.5e-86 yhbS S N-acetyltransferase
AIIGCJOP_04062 9.7e-79 yhbP S Belongs to the UPF0306 family
AIIGCJOP_04063 5.8e-86 yfkM 3.5.1.124 S intracellular protease
AIIGCJOP_04064 3.8e-111 yraR GM Nucleoside-diphosphate-sugar epimerases
AIIGCJOP_04065 1.6e-84 yraP S bacterial OsmY and nodulation domain
AIIGCJOP_04066 3.2e-104 gmhA 2.7.1.167, 2.7.1.33, 2.7.7.70, 5.3.1.28 G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
AIIGCJOP_04067 4e-63 yraN L Belongs to the UPF0102 family
AIIGCJOP_04068 0.0 lpoA M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a)
AIIGCJOP_04069 1.4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AIIGCJOP_04070 4.8e-142 K filamentation induced by cAMP
AIIGCJOP_04071 1.8e-276 garD 4.2.1.42, 4.2.1.7 G Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate
AIIGCJOP_04072 1.6e-244 garP G transporter
AIIGCJOP_04073 1.1e-141 garL 4.1.2.20, 4.1.2.52 G Belongs to the HpcH HpaI aldolase family
AIIGCJOP_04074 3.7e-157 garR 1.1.1.60 I Catalyzes the reduction of tatronate semialdehyde to D- glycerate
AIIGCJOP_04075 2e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AIIGCJOP_04076 3.4e-231 yhaO E Serine transporter
AIIGCJOP_04077 2e-207 yhaM S Belongs to the UPF0597 family
AIIGCJOP_04078 4.5e-126 yhaK S Belongs to the pirin family
AIIGCJOP_04079 2.1e-160 yhaJ K transcriptional regulator
AIIGCJOP_04080 4.4e-64 yhaH S Membrane
AIIGCJOP_04081 1.1e-197 yqjG 1.8.5.7, 2.5.1.18 O Glutathione S-Transferase
AIIGCJOP_04082 1.2e-64 yqjF S membrane
AIIGCJOP_04083 3.7e-35 yqjK S YqjK-like protein
AIIGCJOP_04084 3.1e-48 yqjE S Membrane
AIIGCJOP_04085 5.7e-25 yqjD S Membrane protein YqjD
AIIGCJOP_04086 8.7e-28 yqjC S Protein of unknown function (DUF1090)
AIIGCJOP_04087 2.1e-54 mzrA S SecD export protein N-terminal TM region
AIIGCJOP_04088 2.8e-117 yqjA S Inner membrane protein yqjA
AIIGCJOP_04089 1.5e-141 exuR K Transcriptional
AIIGCJOP_04090 1.7e-235 exuT G Major facilitator superfamily
AIIGCJOP_04091 2.2e-276 uxaC 5.3.1.12 G glucuronate isomerase
AIIGCJOP_04092 2.1e-282 uxaA 4.2.1.7 G Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate
AIIGCJOP_04093 7.1e-207 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AIIGCJOP_04094 7.3e-167 alx P membrane protein, terc
AIIGCJOP_04095 3.9e-179 ygjR S oxidoreductase
AIIGCJOP_04096 4.2e-89 ygjP S WLM domain
AIIGCJOP_04097 1.1e-211 rlmG 2.1.1.172, 2.1.1.174 J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA
AIIGCJOP_04098 0.0 fadH 1.3.1.34 C PFAM NADH flavin oxidoreductase NADH oxidase
AIIGCJOP_04099 1.1e-297 lsrK 2.7.1.17, 2.7.1.189, 2.7.1.5 G Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3- dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position
AIIGCJOP_04100 1.6e-166 lsrR K transcriptional regulator
AIIGCJOP_04101 4.2e-270 lsrA 3.6.3.17 P Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system
AIIGCJOP_04102 1.1e-173 lsrC U Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_04103 9.4e-162 lsrD U Belongs to the binding-protein-dependent transport system permease family
AIIGCJOP_04104 1.9e-181 lsrB G Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases
AIIGCJOP_04105 9.1e-164 lsrF 2.3.1.245, 4.1.2.13 G Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA
AIIGCJOP_04106 5.7e-46 lsrG 5.3.1.32 S Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD)
AIIGCJOP_04107 9.8e-258 patA 2.6.1.11, 2.6.1.17, 2.6.1.82 H Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine
AIIGCJOP_04108 1.2e-184 aer T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
AIIGCJOP_04109 8.4e-173 cheM NT Four helix bundle sensory module for signal transduction
AIIGCJOP_04110 3.7e-75 yqjI K transcriptional regulator
AIIGCJOP_04111 2.5e-138 yqjH 1.16.1.9 P Siderophore-interacting protein
AIIGCJOP_04112 1.7e-197 I Heat shock protein
AIIGCJOP_04113 3.4e-55 S Cellulose biosynthesis protein BcsO
AIIGCJOP_04114 1.2e-146 yhjQ D cellulose synthase operon protein YhjQ
AIIGCJOP_04115 0.0 bcsA 2.4.1.12 GT2 M Cellulose synthase
AIIGCJOP_04116 0.0 bcsB NU cellulose synthase
AIIGCJOP_04117 0.0 bcsC 1.8.1.9, 2.7.11.1 O Cellulose synthase operon protein C C-terminus (BCSC_C)
AIIGCJOP_04118 3.6e-79 bcsD S cellulose synthase
AIIGCJOP_04119 5.9e-188 celC 3.2.1.4 GH8 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
AIIGCJOP_04120 6.7e-38
AIIGCJOP_04122 8.9e-48 L Phage integrase family
AIIGCJOP_04123 5.6e-35 L Transposase and inactivated derivatives
AIIGCJOP_04124 1e-21 L Homeodomain-like domain
AIIGCJOP_04126 1.9e-195 VP0380 L Arm DNA-binding domain
AIIGCJOP_04127 3.4e-256 alsT E alanine symporter
AIIGCJOP_04128 4.6e-162 phoH T PhoH-like protein
AIIGCJOP_04129 6.6e-240 efeB P peroxidase
AIIGCJOP_04130 4.8e-202 efeO P periplasmic lipoprotein involved in iron transport
AIIGCJOP_04131 6.1e-146 efeU P PFAM Iron permease FTR1
AIIGCJOP_04132 1.2e-200 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AIIGCJOP_04133 3.3e-71 J Protein of unknown function (DUF3574)
AIIGCJOP_04134 3.6e-269 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AIIGCJOP_04135 0.0 putA 1.2.1.88, 1.3.8.7, 1.5.5.2 C Oxidizes proline to glutamate for use as a carbon and nitrogen source
AIIGCJOP_04136 4e-55 S Lysozyme inhibitor LprI
AIIGCJOP_04137 2.1e-109 rutR K transcriptional regulator
AIIGCJOP_04138 1.5e-205 rutA 1.14.99.46 C Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate
AIIGCJOP_04139 3.2e-124 rutB 3.5.1.110 Q In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2
AIIGCJOP_04140 3.4e-67 rutC 3.5.99.10 J May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation
AIIGCJOP_04141 2.8e-135 rutD F May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation
AIIGCJOP_04142 1.2e-106 rutE C May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted
AIIGCJOP_04143 6.5e-87 rutF 1.5.1.36 C Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway
AIIGCJOP_04144 2e-223 rutG F Xanthine uracil
AIIGCJOP_04145 2.6e-145 yedA EG of the drug metabolite transporter (DMT) superfamily
AIIGCJOP_04146 4.6e-103 wrbA 1.6.5.2 S Belongs to the WrbA family
AIIGCJOP_04147 9.5e-33 yccJ S YccJ-like protein
AIIGCJOP_04148 4.3e-228 agp 3.1.3.10 S Acid phosphatase
AIIGCJOP_04149 5.1e-70 K transcriptional regulator
AIIGCJOP_04150 7.4e-88 S 50S ribosomal protein L21
AIIGCJOP_04152 1e-96 K transcriptional regulator
AIIGCJOP_04153 3.9e-71 S Domain of unknown function (DUF4865)
AIIGCJOP_04154 1.6e-56 5.3.2.6 S tautomerase
AIIGCJOP_04155 2.5e-45 yphJ 4.1.1.44 I decarboxylase
AIIGCJOP_04156 5e-130 dgdR K transcriptional regulator
AIIGCJOP_04157 1.5e-308 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AIIGCJOP_04158 3.9e-126 MA20_10370 2.1.1.63, 3.2.2.21 K AraC family transcriptional regulator
AIIGCJOP_04159 6.6e-78 S YcxB-like protein
AIIGCJOP_04161 7.2e-89 S HTH domain
AIIGCJOP_04162 3.5e-114 yddE S phenazine biosynthesis protein PhzF
AIIGCJOP_04163 1.2e-12 emrE P Small multidrug resistance protein
AIIGCJOP_04164 9.7e-15 emrE P Multidrug Resistance protein
AIIGCJOP_04165 0.0 cutC 4.3.99.4 C Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde
AIIGCJOP_04166 5.2e-80 1.97.1.4 C Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S- adenosyl-L-methionine (SAM)
AIIGCJOP_04168 3.4e-27 ygdR S (Lipo)protein
AIIGCJOP_04170 6.9e-156 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
AIIGCJOP_04171 7.1e-80 D Membrane
AIIGCJOP_04172 5.5e-307 T Diguanylate cyclase
AIIGCJOP_04173 1.8e-76 S Oxidoreductase molybdopterin binding domain
AIIGCJOP_04174 7.9e-80 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AIIGCJOP_04175 7e-115 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AIIGCJOP_04176 1e-67 mocA 1.1.1.328, 2.7.7.76 S Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process
AIIGCJOP_04177 1.1e-26 MA20_39405 S Protein of unknown function (DUF1272)
AIIGCJOP_04178 1.1e-229 yndD E xaa-pro aminopeptidase
AIIGCJOP_04179 4.1e-185 ampC 3.5.2.6 V Beta-lactamase
AIIGCJOP_04180 9.1e-102 NU Fimbrial protein
AIIGCJOP_04181 0.0 fimD_3 NU PapC N-terminal domain
AIIGCJOP_04182 3.8e-90 NU Pili assembly chaperone PapD, C-terminal domain
AIIGCJOP_04183 7.5e-47 NU Fimbrial protein
AIIGCJOP_04184 1.3e-196 namA 1.6.99.1 C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
AIIGCJOP_04185 7e-248 G Major facilitator superfamily
AIIGCJOP_04186 1e-254 1.1.1.3 E homoserine dehydrogenase
AIIGCJOP_04187 5.5e-137 glxR 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
AIIGCJOP_04188 9.9e-167 K Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression
AIIGCJOP_04191 1.5e-134 S Serine aminopeptidase, S33
AIIGCJOP_04192 0.0 1.1.5.2 G Dehydrogenase
AIIGCJOP_04193 5.2e-33
AIIGCJOP_04194 0.0 betT U BCCT, betaine/carnitine/choline family transporter
AIIGCJOP_04196 1.4e-300 oppA-1 E ABC transporter substrate-binding protein
AIIGCJOP_04197 5.3e-108 yccA S Belongs to the BI1 family
AIIGCJOP_04198 3.7e-57 tusE P part of a sulfur-relay system
AIIGCJOP_04199 2.5e-43 acyP 3.6.1.7 C Acylphosphate phosphohydrolase
AIIGCJOP_04200 3.9e-118 ybcM K helix_turn_helix, arabinose operon control protein
AIIGCJOP_04201 6.5e-75 ybcL S Phosphatidylethanolamine-binding protein
AIIGCJOP_04202 2.5e-225 rlmI 2.1.1.191 J Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA
AIIGCJOP_04203 9.1e-50 hspQ S Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress
AIIGCJOP_04204 1.3e-67 yccU 2.5.1.49 S CoA-binding protein
AIIGCJOP_04205 4.5e-115 yccT S Belongs to the UPF0319 family
AIIGCJOP_04206 6.1e-79 mgsA 4.2.3.3 G Methylglyoxal synthase
AIIGCJOP_04207 0.0 helD 3.6.4.12 L DNA helicase
AIIGCJOP_04208 5.9e-71 yccF S Membrane
AIIGCJOP_04209 0.0 yccS S Membrane
AIIGCJOP_04210 3.7e-87 sxy K regulator of competence-specific genes
AIIGCJOP_04211 6.5e-78 sulA D Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
AIIGCJOP_04212 5.3e-195 ompA M Belongs to the ompA family
AIIGCJOP_04213 1.5e-77 matP D Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain
AIIGCJOP_04214 0.0 ycbZ O Belongs to the peptidase S16 family
AIIGCJOP_04215 1.1e-97 fabA 4.2.1.59, 5.3.3.14 I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length
AIIGCJOP_04216 4.2e-98 ymbA S protein conserved in bacteria
AIIGCJOP_04217 1.1e-282 pqiB Q paraquat-inducible protein b
AIIGCJOP_04218 3.7e-211 pqiA S paraquat-inducible protein A
AIIGCJOP_04219 0.0 uup S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AIIGCJOP_04220 0.0 rlmL 2.1.1.173, 2.1.1.191, 2.1.1.264, 2.1.1.72 J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AIIGCJOP_04221 6.2e-202 ycbX 1.17.1.1 C Mosc domain protein beta barrel domain protein
AIIGCJOP_04222 4.9e-96 zapC D Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ
AIIGCJOP_04223 5.1e-187 pyrD 1.3.1.14, 1.3.5.2 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
AIIGCJOP_04224 1.2e-100 ssuE 1.5.1.38 S fmn reductase
AIIGCJOP_04225 2.1e-166 ssuA P ABC transporter
AIIGCJOP_04226 2.2e-210 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
AIIGCJOP_04227 6.3e-132 ssuC 1.14.14.5 P ABC-type nitrate sulfonate bicarbonate transport system permease component
AIIGCJOP_04228 3e-131 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
AIIGCJOP_04229 0.0 pepN 3.4.11.2 E aminopeptidase N
AIIGCJOP_04230 2.1e-224 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AIIGCJOP_04231 5.3e-267 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AIIGCJOP_04232 7.1e-195 M Belongs to the Gram-negative porin family
AIIGCJOP_04233 4.7e-224 aspC 2.6.1.1, 2.6.1.57 E aminotransferase
AIIGCJOP_04234 1.8e-124 ycbL 3.1.2.6 P COG0491 Zn-dependent hydrolases, including glyoxylases
AIIGCJOP_04235 3.7e-99 ycbK S protein conserved in bacteria
AIIGCJOP_04236 0.0 ycbB M protein conserved in bacteria
AIIGCJOP_04237 0.0 mukB 3.5.4.40 D Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AIIGCJOP_04238 2.1e-126 mukE D Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AIIGCJOP_04239 1.4e-245 mukF D Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AIIGCJOP_04240 7.3e-141 cmoM GT2,GT4 J Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs
AIIGCJOP_04241 8.3e-129 ycbC S Gram-negative-bacterium-type cell wall biogenesis
AIIGCJOP_04242 5.5e-169 ycbJ S Phosphotransferase enzyme family
AIIGCJOP_04243 1.6e-132 kdsB 2.7.7.38 M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AIIGCJOP_04244 1.2e-25 ycaR 2.7.1.130 S Belongs to the UPF0434 family
AIIGCJOP_04245 1.8e-223 ycaQ S protein conserved in bacteria
AIIGCJOP_04246 4.4e-175 lpxK 2.7.1.130 F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
AIIGCJOP_04247 0.0 msbA V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
AIIGCJOP_04248 0.0 ycaI S DNA internalization-related competence protein ComEC Rec2
AIIGCJOP_04249 1.9e-46 L Bacterial DNA-binding protein
AIIGCJOP_04250 0.0 rpsA 1.17.7.4 J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
AIIGCJOP_04251 5.4e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AIIGCJOP_04252 1.5e-236 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AIIGCJOP_04253 3.9e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AIIGCJOP_04254 3e-122 ycaP S Membrane
AIIGCJOP_04255 0.0 ycaO O redox protein regulator of disulfide bond formation
AIIGCJOP_04256 1.3e-145 focA P Formate nitrite
AIIGCJOP_04257 0.0 pflB 2.3.1.54 C formate C-acetyltransferase glycine radical
AIIGCJOP_04258 1.2e-145 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AIIGCJOP_04259 5.9e-38 cigR S response to cobalt ion
AIIGCJOP_04260 1.2e-208 ycaD EGP Major facilitator superfamily
AIIGCJOP_04261 3e-143 dmsC S PFAM DMSO reductase anchor subunit (DmsC)
AIIGCJOP_04262 1.6e-122 dmsB C reductase, chain B
AIIGCJOP_04263 0.0 dmsA 1.8.5.3, 1.97.1.9 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AIIGCJOP_04264 1.4e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AIIGCJOP_04265 2.1e-252 rarA L MgsA AAA+ ATPase C terminal
AIIGCJOP_04266 8.9e-110 lolA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AIIGCJOP_04267 0.0 ftsK D PFAM cell divisionFtsK SpoIIIE
AIIGCJOP_04268 8.5e-87 lrp K Transcriptional regulator
AIIGCJOP_04269 9.5e-183 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AIIGCJOP_04270 0.0 cydD V (ABC) transporter
AIIGCJOP_04271 1.9e-295 cydC V (ABC) transporter
AIIGCJOP_04272 7.8e-126 aat 2.3.2.6 O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AIIGCJOP_04273 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AIIGCJOP_04274 1.1e-42
AIIGCJOP_04275 0.0 clpA O Belongs to the ClpA ClpB family
AIIGCJOP_04276 1.2e-54 clpS S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AIIGCJOP_04277 1.1e-36 cspD K Cold shock
AIIGCJOP_04278 0.0 macB V Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides
AIIGCJOP_04279 5.8e-192 macA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AIIGCJOP_04280 8e-166 ybjX S protein conserved in bacteria
AIIGCJOP_04281 0.0 ybjD L ATP-dependent endonuclease of the OLD family
AIIGCJOP_04282 3.7e-120 aqpZ G Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity
AIIGCJOP_04283 1.7e-149 ybjE S membrane
AIIGCJOP_04284 0.0 hcp 1.7.99.1 C hydroxylamine reductase activity
AIIGCJOP_04285 1.1e-178 hcr C oxidoreductase
AIIGCJOP_04286 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AIIGCJOP_04287 2.4e-181 ltaE 4.1.2.48 E PFAM aromatic amino acid beta-eliminating lyase threonine aldolase
AIIGCJOP_04288 2.6e-261 ybjT GM Epimerase dehydratase
AIIGCJOP_04289 1.6e-193 ybjS 1.1.1.133, 5.1.3.13 M 3-beta hydroxysteroid dehydrogenase
AIIGCJOP_04290 0.0 MU Chitinase class I
AIIGCJOP_04291 1e-70 iagB M invasion protein IagB
AIIGCJOP_04292 0.0 chiA 3.2.1.14 GH18 G chitinase
AIIGCJOP_04293 2e-117 3.4.23.43 NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AIIGCJOP_04294 3.9e-68 gspM U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AIIGCJOP_04295 2.6e-171 gspL U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AIIGCJOP_04296 2.7e-140 gspK U COG3156 Type II secretory pathway component PulK
AIIGCJOP_04297 6.4e-98 gspJ U General secretion pathway protein J
AIIGCJOP_04298 1.1e-48 gspI NU general secretion pathway protein
AIIGCJOP_04299 1.1e-75 gspH NU general secretion pathway protein
AIIGCJOP_04300 1.9e-77 gspG U General Secretion Pathway protein
AIIGCJOP_04301 2.9e-256 MU Autotransporter beta-domain
AIIGCJOP_04302 4.2e-28 ygdi3 S Bacterial protein of unknown function (DUF903)
AIIGCJOP_04303 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthetase ammonia chain
AIIGCJOP_04304 1.2e-216 carA 6.3.5.5 F Belongs to the CarA family
AIIGCJOP_04305 6.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AIIGCJOP_04306 5e-95 alaS_2 6.1.1.7 S Alanyl-tRNA synthetase
AIIGCJOP_04307 1.7e-157 K transcriptional regulator
AIIGCJOP_04308 5.1e-173 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AIIGCJOP_04309 2.8e-76 fkpB 5.2.1.8 G Peptidyl-prolyl cis-trans
AIIGCJOP_04310 6.6e-87 lspA 3.4.23.36 M This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AIIGCJOP_04311 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AIIGCJOP_04312 7.3e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AIIGCJOP_04313 3.3e-37 rpsT J 30S ribosomal protein S20
AIIGCJOP_04314 4.4e-166 nhaR K Transcriptional regulator
AIIGCJOP_04315 1e-178 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AIIGCJOP_04316 7.7e-176 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AIIGCJOP_04317 0.0 dnaK O Heat shock 70 kDa protein
AIIGCJOP_04318 4.7e-97 yaaH S GPR1 FUN34 yaaH family protein
AIIGCJOP_04319 1.1e-213 tphA EGP Major facilitator superfamily
AIIGCJOP_04320 5e-102 mog 2.7.7.75, 2.8.1.12 H Molybdenum cofactor
AIIGCJOP_04321 5.2e-173 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AIIGCJOP_04322 1.9e-235 yaaJ E alanine symporter
AIIGCJOP_04323 2.7e-135 yaaA S Belongs to the UPF0246 family
AIIGCJOP_04324 7.3e-14 yaaX S Protein of unknown function (DUF2502)
AIIGCJOP_04325 1.7e-243 thrC 4.2.3.1 E Threonine synthase
AIIGCJOP_04326 8e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AIIGCJOP_04327 0.0 thrA 1.1.1.3, 2.7.2.4 E belongs to the aspartokinase family
AIIGCJOP_04329 1.3e-114 trmJ 2.1.1.200 J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AIIGCJOP_04330 1.1e-132 K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AIIGCJOP_04331 5.7e-218 creD V Inner membrane protein CreD
AIIGCJOP_04332 3.1e-230 T PhoQ Sensor
AIIGCJOP_04333 1.1e-119 K Transcriptional regulatory protein, C terminal
AIIGCJOP_04334 1.2e-77 creA S protein conserved in bacteria
AIIGCJOP_04335 3.6e-165 rob K Binds to the right arm of the replication origin oriC
AIIGCJOP_04336 2e-115 gpmB 5.4.2.12 G Belongs to the phosphoglycerate mutase family
AIIGCJOP_04337 2.6e-86 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AIIGCJOP_04338 3.8e-51 trpR K This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AIIGCJOP_04339 0.0 slt GH23 M Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
AIIGCJOP_04340 0.0 yjjK 3.6.3.25 S A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P site) into the translation elongation cycle by using a mechanism sensitive to the ATP ADP ratio. Binds to the 70S ribosome E site where it modulates the state of the translating ribosome during subunit translocation
AIIGCJOP_04341 7.5e-241 nadR 2.7.1.22, 2.7.7.1 H transcriptional regulator
AIIGCJOP_04342 3.5e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AIIGCJOP_04343 1.1e-175 serB 3.1.3.3 E phosphoserine phosphatase
AIIGCJOP_04344 2.2e-106 smp 2.4.1.15, 2.4.1.347, 2.7.13.3, 6.3.1.20 GT20 S membrane protein affecting hemolysin expression
AIIGCJOP_04345 6.9e-192 lplA 6.3.1.20 H Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes
AIIGCJOP_04346 4.8e-131 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
AIIGCJOP_04347 2.8e-240 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
AIIGCJOP_04348 1.2e-239 deoA 2.4.2.2, 2.4.2.4 F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AIIGCJOP_04349 1.4e-136 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AIIGCJOP_04350 9.6e-278 yjjI F anaerobic respiration
AIIGCJOP_04351 2.3e-127 yjjW 1.97.1.4 O 4Fe-4S single cluster domain
AIIGCJOP_04352 7.1e-128 yjjV L Deoxyribonuclease
AIIGCJOP_04353 9.8e-197 yjjU I esterase of the alpha-beta hydrolase superfamily
AIIGCJOP_04354 1.6e-18 ytjA S UPF0391 membrane protein
AIIGCJOP_04355 9e-94 osmY S Periplasmic or secreted lipoprotein
AIIGCJOP_04356 1.1e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AIIGCJOP_04357 1.4e-119 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S hydrolase
AIIGCJOP_04358 5.1e-75 rimI 2.3.1.128, 2.3.1.234 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AIIGCJOP_04359 1e-64 holD 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AIIGCJOP_04360 2.2e-193 rsmC 2.1.1.172, 2.1.1.174 J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle
AIIGCJOP_04364 2.4e-23 yjjZ S Protein of unknown function (DUF1435)
AIIGCJOP_04365 2.9e-137 fhuF S Iron reductase
AIIGCJOP_04366 4.5e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AIIGCJOP_04367 2.3e-76 ywhH S Prolyl-tRNA synthetase
AIIGCJOP_04368 6.3e-88 bglJ K transcriptional
AIIGCJOP_04369 4.8e-94 yjjQ K regulator
AIIGCJOP_04370 2.9e-134 yjjP S Membrane
AIIGCJOP_04371 1.8e-78 yjjB S UPF0442 protein
AIIGCJOP_04372 4.6e-109 nicS K transcriptional regulator
AIIGCJOP_04373 2.1e-73 ohr O Organic Hydroperoxide Resistance Protein
AIIGCJOP_04374 1.8e-93 dnaT L it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'
AIIGCJOP_04375 5.5e-130 dnaC L DNA replication protein
AIIGCJOP_04376 1.9e-44 yjjA S Glycoprotein Receptor
AIIGCJOP_04377 0.0 mdoB 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AIIGCJOP_04378 2.1e-190 tsr NT chemotaxis, protein
AIIGCJOP_04379 1.2e-60 hpaR K Homoprotocatechuate degradative operon repressor
AIIGCJOP_04380 1e-224 hpaG 4.1.1.68 Q 4-hydroxyphenylacetate degradation bifunctional isomerase
AIIGCJOP_04381 5.2e-281 hpaE 1.2.1.60 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_04382 3.7e-162 hpaD 1.13.11.15 S 3,4-dihydroxyphenylacetate 2,3-dioxygenase
AIIGCJOP_04383 4.6e-64 hpcD 4.1.1.68, 5.3.3.10 E 5-carboxymethyl-2-hydroxymuconate isomerase
AIIGCJOP_04384 3e-150 hpaH Q hydratase
AIIGCJOP_04385 3.2e-136 hpaI 4.1.2.20, 4.1.2.52 G HpcH/HpaI aldolase/citrate lyase family
AIIGCJOP_04386 1.7e-241 hpaX G Major facilitator superfamily
AIIGCJOP_04387 2.4e-164 hpaA K AraC-like ligand binding domain
AIIGCJOP_04388 1.2e-111 K Transcriptional regulator, AbiEi antitoxin N-terminal domain
AIIGCJOP_04389 2.8e-152 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
AIIGCJOP_04390 2.2e-311 hpaB 1.14.14.9 Q 4-hydroxyphenylacetate 3-monooxygenase oxygenase component
AIIGCJOP_04391 1.3e-85 hpaC 1.5.1.36 S 4-hydroxyphenylacetate 3-monooxygenase, reductase component
AIIGCJOP_04392 5.7e-43
AIIGCJOP_04393 4.9e-288 kpsD M polysaccharide export
AIIGCJOP_04394 2.4e-131 kpsM GM Transport Permease Protein
AIIGCJOP_04395 1.1e-66 kpsT 3.6.3.38 GM ABC transporter
AIIGCJOP_04396 2e-187 kpsE M COG3524 Capsule polysaccharide export protein
AIIGCJOP_04397 3.9e-84 GT2,GT4 S Glycosyltransferase like family 2
AIIGCJOP_04398 2.3e-117 wgeG M Glycosyl transferase 4-like domain
AIIGCJOP_04402 8.8e-149 M Glycosyltransferase family 92
AIIGCJOP_04403 4e-253 GT2,GT4 G Glycosyl transferase, family 2
AIIGCJOP_04404 1.2e-172 rgpF GT2,GT4 M transferase activity, transferring glycosyl groups
AIIGCJOP_04405 4.8e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AIIGCJOP_04406 2.5e-161 rfbD 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AIIGCJOP_04407 2.1e-157 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AIIGCJOP_04408 1.5e-95 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AIIGCJOP_04409 0.0 kpsC M Capsule polysaccharide biosynthesis protein
AIIGCJOP_04410 1.9e-223 kpsS M capsule polysaccharide
AIIGCJOP_04411 6e-185 insH5 L COG3039 Transposase and inactivated derivatives IS5 family
AIIGCJOP_04412 5.5e-145 K transcriptional regulator
AIIGCJOP_04413 0.0 cstA T Carbon starvation protein
AIIGCJOP_04414 5.9e-34 yjiX S small protein
AIIGCJOP_04415 2.9e-176 yjiA S cobalamin synthesis protein
AIIGCJOP_04416 1.6e-94 S YfaZ precursor
AIIGCJOP_04417 1.2e-250 gabD 1.2.1.16, 1.2.1.20, 1.2.1.24, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_04418 4.6e-77 S Type VI secretion system effector
AIIGCJOP_04419 1.2e-12
AIIGCJOP_04420 1.7e-104
AIIGCJOP_04421 2.1e-35 S BrnA antitoxin of type II toxin-antitoxin system
AIIGCJOP_04422 3.1e-117 ybfI K transcriptional regulator
AIIGCJOP_04423 6.5e-90 rhtC E PFAM Lysine exporter protein (LYSE YGGA)
AIIGCJOP_04424 8.1e-230 yjiN S Membrane
AIIGCJOP_04425 1.3e-185 3.2.1.172 GH105 S PFAM glycosyl hydrolase family 88
AIIGCJOP_04426 2.8e-98
AIIGCJOP_04427 8.2e-283 3.2.1.139 G Belongs to the glycosyl hydrolase 67 family
AIIGCJOP_04428 3.4e-189 S Protein of unknown function (DUF2955)
AIIGCJOP_04429 3.5e-186 yiaV V Secretion Protein
AIIGCJOP_04430 2.9e-76 slyA K Transcriptional regulator
AIIGCJOP_04432 9.2e-35 S Protein of unknown function (DUF1778)
AIIGCJOP_04433 1.4e-71 Z012_05445 2.3.1.189 K acetyltransferase
AIIGCJOP_04434 2.5e-108 ydfF K transcriptional regulator
AIIGCJOP_04435 3e-58 1.3.1.12 S ACT domain protein
AIIGCJOP_04436 5.5e-50 yqjZ C Antibiotic biosynthesis monooxygenase
AIIGCJOP_04437 1.5e-240 1.2.1.3 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_04438 2.8e-152 K transcriptional regulator
AIIGCJOP_04439 2.4e-78 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AIIGCJOP_04440 1.1e-251 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AIIGCJOP_04441 4.7e-18 yjiS S Domain of unknown function (DUF1127)
AIIGCJOP_04442 1.2e-234 yjiR K Transcriptional regulator
AIIGCJOP_04443 0.0 foxA P Receptor
AIIGCJOP_04444 9.1e-165 K Transcriptional regulator
AIIGCJOP_04445 1e-26 S Uncharacterized protein conserved in bacteria (DUF2171)
AIIGCJOP_04446 1.2e-22
AIIGCJOP_04447 4.9e-215 ycfD 1.14.11.47 S Cupin 4 family protein
AIIGCJOP_04448 1.2e-32
AIIGCJOP_04449 4.2e-125 glpR_5 K Transcriptional Regulator, DeoR family
AIIGCJOP_04451 1.1e-180 ybjJ EGP Major facilitator Superfamily
AIIGCJOP_04452 2.2e-61 yyaH 4.4.1.5 E bleomycin resistance protein
AIIGCJOP_04453 0.0 mcrB TV AAA domain (dynein-related subfamily)
AIIGCJOP_04454 6.8e-184 mcrC V McrBC 5-methylcytosine restriction system component
AIIGCJOP_04455 1.4e-94 K response regulator
AIIGCJOP_04456 0.0 fixL T Histidine kinase
AIIGCJOP_04457 6.4e-55 T response regulator
AIIGCJOP_04458 7e-40 S ABC transporter substrate-binding protein
AIIGCJOP_04459 1.4e-27 S Protein of unknown function (DUF1427)
AIIGCJOP_04460 8.4e-126 ycaC Q Hydrolase
AIIGCJOP_04461 0.0 S metal-dependent hydrolase with the TIM-barrel fold
AIIGCJOP_04462 3.4e-65 1.6.99.3, 1.8.5.2 S LysR family transcriptional regulator
AIIGCJOP_04463 1.3e-293 EGP permeases of the major facilitator superfamily
AIIGCJOP_04464 1.4e-155 cpo 1.11.1.10 I Alpha beta hydrolase
AIIGCJOP_04465 1.6e-73 fosB 2.5.1.18 E Glutathione transferase
AIIGCJOP_04466 6.6e-10
AIIGCJOP_04467 2.2e-268 prr 1.2.1.19, 1.2.1.3 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_04468 4e-265 E amino acid
AIIGCJOP_04469 2.5e-178 csiD C May be involved in the control of utilization of gamma- aminobutyric acid
AIIGCJOP_04470 9.4e-223 lhgO S L-2-hydroxyglutarate oxidase LhgO
AIIGCJOP_04471 4.5e-269 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
AIIGCJOP_04472 8.9e-237 gabT 2.6.1.19, 2.6.1.22, 2.6.1.48 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AIIGCJOP_04473 2.4e-116 csiR K Transcriptional
AIIGCJOP_04474 9.6e-191 2.7.11.1 S protein related to capsule biosynthesis enzymes
AIIGCJOP_04475 3.4e-42 K Helix-turn-helix XRE-family like proteins
AIIGCJOP_04476 1.1e-29 S acyl carrier protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)