ORF_ID e_value Gene_name EC_number CAZy COGs Description
MPDNDLLC_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MPDNDLLC_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MPDNDLLC_00003 1.1e-29 yyzM S Protein conserved in bacteria
MPDNDLLC_00004 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MPDNDLLC_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MPDNDLLC_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MPDNDLLC_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MPDNDLLC_00008 2.7e-61 divIC D Septum formation initiator
MPDNDLLC_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
MPDNDLLC_00011 1.4e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MPDNDLLC_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MPDNDLLC_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MPDNDLLC_00014 2.4e-164 L Transposase
MPDNDLLC_00015 1.1e-92 L Transposase
MPDNDLLC_00016 2.7e-28 L transposition
MPDNDLLC_00017 5.5e-81 L Integrase core domain protein
MPDNDLLC_00030 5.3e-11
MPDNDLLC_00036 1.3e-140 mreC M Involved in formation and maintenance of cell shape
MPDNDLLC_00037 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MPDNDLLC_00038 8.6e-97 usp 3.5.1.28 CBM50 S CHAP domain
MPDNDLLC_00039 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MPDNDLLC_00040 2.9e-218 araT 2.6.1.1 E Aminotransferase
MPDNDLLC_00041 7e-144 recO L Involved in DNA repair and RecF pathway recombination
MPDNDLLC_00042 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MPDNDLLC_00043 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MPDNDLLC_00044 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MPDNDLLC_00045 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MPDNDLLC_00046 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MPDNDLLC_00047 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MPDNDLLC_00048 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MPDNDLLC_00049 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MPDNDLLC_00050 1e-90 L transposase activity
MPDNDLLC_00051 3.4e-50 L transposition
MPDNDLLC_00052 2e-32 L Integrase core domain protein
MPDNDLLC_00053 2.3e-161 S CHAP domain
MPDNDLLC_00054 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
MPDNDLLC_00055 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MPDNDLLC_00056 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MPDNDLLC_00057 9.2e-141 1.1.1.169 H Ketopantoate reductase
MPDNDLLC_00058 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MPDNDLLC_00059 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MPDNDLLC_00060 8.2e-70 argR K Regulates arginine biosynthesis genes
MPDNDLLC_00061 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MPDNDLLC_00062 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MPDNDLLC_00063 7e-34 S Protein of unknown function (DUF3021)
MPDNDLLC_00064 1.2e-61 KT phosphorelay signal transduction system
MPDNDLLC_00066 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MPDNDLLC_00068 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MPDNDLLC_00069 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
MPDNDLLC_00070 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
MPDNDLLC_00071 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MPDNDLLC_00072 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
MPDNDLLC_00074 1.9e-07
MPDNDLLC_00079 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MPDNDLLC_00080 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MPDNDLLC_00081 5.5e-36 XK27_02060 S Transglycosylase associated protein
MPDNDLLC_00082 1.3e-54 badR K DNA-binding transcription factor activity
MPDNDLLC_00083 3.5e-97 S reductase
MPDNDLLC_00084 6.9e-89 L Integrase core domain protein
MPDNDLLC_00085 6.4e-41 L transposition
MPDNDLLC_00087 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
MPDNDLLC_00088 4.6e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MPDNDLLC_00090 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
MPDNDLLC_00091 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MPDNDLLC_00092 1.1e-83 S Putative small multi-drug export protein
MPDNDLLC_00093 6.2e-76 ctsR K Belongs to the CtsR family
MPDNDLLC_00094 0.0 clpC O Belongs to the ClpA ClpB family
MPDNDLLC_00095 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MPDNDLLC_00096 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MPDNDLLC_00097 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MPDNDLLC_00098 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MPDNDLLC_00099 6.9e-144 S SseB protein N-terminal domain
MPDNDLLC_00100 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
MPDNDLLC_00101 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MPDNDLLC_00102 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MPDNDLLC_00105 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MPDNDLLC_00106 3.5e-91 yacP S RNA-binding protein containing a PIN domain
MPDNDLLC_00107 3.4e-155 degV S DegV family
MPDNDLLC_00109 1.8e-31 K helix-turn-helix
MPDNDLLC_00110 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MPDNDLLC_00111 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MPDNDLLC_00112 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MPDNDLLC_00113 1.5e-35 K sequence-specific DNA binding
MPDNDLLC_00115 0.0 S Lantibiotic dehydratase, C terminus
MPDNDLLC_00116 1.6e-230 spaC2 V Lanthionine synthetase C family protein
MPDNDLLC_00117 4.3e-183 EGP Major facilitator Superfamily
MPDNDLLC_00118 5.9e-24 3.6.4.12
MPDNDLLC_00119 5.9e-91 3.6.4.12 K Divergent AAA domain protein
MPDNDLLC_00120 7.4e-225 int L Belongs to the 'phage' integrase family
MPDNDLLC_00121 1.8e-38 S Helix-turn-helix domain
MPDNDLLC_00122 4.9e-173
MPDNDLLC_00124 3.4e-75 isp2 S pathogenesis
MPDNDLLC_00125 5.7e-91 tnp L Transposase
MPDNDLLC_00126 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
MPDNDLLC_00127 1.6e-108 capA M Bacterial capsule synthesis protein
MPDNDLLC_00128 2.5e-58 capA M Bacterial capsule synthesis protein
MPDNDLLC_00129 6.1e-39 gcvR T UPF0237 protein
MPDNDLLC_00130 8.7e-243 XK27_08635 S UPF0210 protein
MPDNDLLC_00131 5.4e-135 ais G Phosphoglycerate mutase
MPDNDLLC_00132 1e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MPDNDLLC_00133 1.3e-102 acmA 3.2.1.17 NU amidase activity
MPDNDLLC_00134 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MPDNDLLC_00135 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MPDNDLLC_00136 1.7e-281 dnaK O Heat shock 70 kDa protein
MPDNDLLC_00137 5.6e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MPDNDLLC_00138 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MPDNDLLC_00139 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
MPDNDLLC_00140 3.3e-72 hmpT S cog cog4720
MPDNDLLC_00142 9.9e-19 S Domain of unknown function (DUF4649)
MPDNDLLC_00143 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
MPDNDLLC_00144 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MPDNDLLC_00145 4e-84
MPDNDLLC_00146 1.6e-77 sigH K DNA-templated transcription, initiation
MPDNDLLC_00147 3.5e-149 ykuT M mechanosensitive ion channel
MPDNDLLC_00148 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MPDNDLLC_00149 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MPDNDLLC_00150 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MPDNDLLC_00151 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
MPDNDLLC_00152 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
MPDNDLLC_00153 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
MPDNDLLC_00154 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MPDNDLLC_00155 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MPDNDLLC_00156 2.4e-83 nrdI F Belongs to the NrdI family
MPDNDLLC_00157 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MPDNDLLC_00158 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MPDNDLLC_00159 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MPDNDLLC_00160 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MPDNDLLC_00161 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MPDNDLLC_00162 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MPDNDLLC_00163 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MPDNDLLC_00164 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MPDNDLLC_00165 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MPDNDLLC_00166 6.5e-202 yhjX P Major Facilitator
MPDNDLLC_00167 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MPDNDLLC_00168 5e-94 V VanZ like family
MPDNDLLC_00170 1e-123 glnQ E abc transporter atp-binding protein
MPDNDLLC_00171 1.8e-276 glnP P ABC transporter
MPDNDLLC_00172 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MPDNDLLC_00173 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MPDNDLLC_00174 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
MPDNDLLC_00175 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MPDNDLLC_00176 6.3e-235 sufD O assembly protein SufD
MPDNDLLC_00177 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MPDNDLLC_00178 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
MPDNDLLC_00179 3.5e-274 sufB O assembly protein SufB
MPDNDLLC_00180 7e-10 oppA E ABC transporter substrate-binding protein
MPDNDLLC_00181 2e-138 oppA E ABC transporter substrate-binding protein
MPDNDLLC_00182 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPDNDLLC_00183 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPDNDLLC_00184 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPDNDLLC_00185 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPDNDLLC_00186 3e-27 oppD P Belongs to the ABC transporter superfamily
MPDNDLLC_00187 2.5e-32 oppD P Belongs to the ABC transporter superfamily
MPDNDLLC_00188 1.2e-62 oppD P Belongs to the ABC transporter superfamily
MPDNDLLC_00189 3.1e-43 oppD P Belongs to the ABC transporter superfamily
MPDNDLLC_00190 7.5e-62 oppF P Belongs to the ABC transporter superfamily
MPDNDLLC_00191 3.4e-62 oppF P Belongs to the ABC transporter superfamily
MPDNDLLC_00192 6.4e-23
MPDNDLLC_00193 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MPDNDLLC_00194 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MPDNDLLC_00195 1.9e-223 EGP Major facilitator Superfamily
MPDNDLLC_00196 3.1e-72 adcR K transcriptional
MPDNDLLC_00197 2.2e-136 adcC P ABC transporter, ATP-binding protein
MPDNDLLC_00198 1.6e-127 adcB P ABC transporter (Permease
MPDNDLLC_00199 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MPDNDLLC_00200 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
MPDNDLLC_00201 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
MPDNDLLC_00202 3.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MPDNDLLC_00203 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
MPDNDLLC_00204 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
MPDNDLLC_00205 1.9e-127 yeeN K transcriptional regulatory protein
MPDNDLLC_00206 9.8e-50 yajC U protein transport
MPDNDLLC_00207 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MPDNDLLC_00208 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
MPDNDLLC_00209 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MPDNDLLC_00210 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MPDNDLLC_00211 0.0 WQ51_06230 S ABC transporter substrate binding protein
MPDNDLLC_00212 5.2e-142 cmpC S abc transporter atp-binding protein
MPDNDLLC_00213 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MPDNDLLC_00214 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MPDNDLLC_00215 1e-90 L transposase activity
MPDNDLLC_00216 6.6e-51 L transposition
MPDNDLLC_00219 4.7e-43
MPDNDLLC_00220 6.8e-56 S TM2 domain
MPDNDLLC_00221 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MPDNDLLC_00222 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MPDNDLLC_00223 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MPDNDLLC_00224 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
MPDNDLLC_00225 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
MPDNDLLC_00226 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
MPDNDLLC_00227 6e-55 cof Q phosphatase activity
MPDNDLLC_00228 6.2e-35 cof Q phosphatase activity
MPDNDLLC_00229 1.6e-137 glcR K transcriptional regulator (DeoR family)
MPDNDLLC_00230 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MPDNDLLC_00231 3.8e-40 K transcriptional
MPDNDLLC_00232 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
MPDNDLLC_00233 6.5e-67 S COG1073 Hydrolases of the alpha beta superfamily
MPDNDLLC_00234 1.1e-65 S COG1073 Hydrolases of the alpha beta superfamily
MPDNDLLC_00235 2.4e-278 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MPDNDLLC_00236 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MPDNDLLC_00237 1.9e-77 yhaI L Membrane
MPDNDLLC_00238 1.7e-259 pepC 3.4.22.40 E aminopeptidase
MPDNDLLC_00239 4.7e-249 L Transposase
MPDNDLLC_00240 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MPDNDLLC_00241 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MPDNDLLC_00242 3.1e-95 ypsA S Belongs to the UPF0398 family
MPDNDLLC_00243 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MPDNDLLC_00244 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MPDNDLLC_00245 2.6e-298 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
MPDNDLLC_00246 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
MPDNDLLC_00247 2.5e-23
MPDNDLLC_00248 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MPDNDLLC_00249 7.3e-80 XK27_09675 K -acetyltransferase
MPDNDLLC_00250 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MPDNDLLC_00251 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MPDNDLLC_00252 5.2e-59 L Integrase core domain protein
MPDNDLLC_00253 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MPDNDLLC_00254 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MPDNDLLC_00255 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MPDNDLLC_00256 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
MPDNDLLC_00257 8.8e-98 ybhL S Belongs to the BI1 family
MPDNDLLC_00260 4.8e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MPDNDLLC_00261 8.1e-91 K transcriptional regulator
MPDNDLLC_00262 7.6e-36 yneF S UPF0154 protein
MPDNDLLC_00263 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MPDNDLLC_00264 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MPDNDLLC_00265 3.5e-99 XK27_09740 S Phosphoesterase
MPDNDLLC_00266 7.8e-85 ykuL S CBS domain
MPDNDLLC_00267 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
MPDNDLLC_00268 2.2e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MPDNDLLC_00269 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MPDNDLLC_00270 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MPDNDLLC_00271 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MPDNDLLC_00272 1.2e-258 trkH P Cation transport protein
MPDNDLLC_00273 1.5e-247 trkA P Potassium transporter peripheral membrane component
MPDNDLLC_00274 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MPDNDLLC_00275 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MPDNDLLC_00276 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
MPDNDLLC_00277 5.6e-161 K sequence-specific DNA binding
MPDNDLLC_00278 1.2e-32 V protein secretion by the type I secretion system
MPDNDLLC_00279 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MPDNDLLC_00280 2.8e-56 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MPDNDLLC_00281 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MPDNDLLC_00282 1.3e-46 yhaI L Membrane
MPDNDLLC_00283 1e-35 S Domain of unknown function (DUF4173)
MPDNDLLC_00284 1.4e-54 S Domain of unknown function (DUF4173)
MPDNDLLC_00285 6.8e-95 ureI S AmiS/UreI family transporter
MPDNDLLC_00286 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MPDNDLLC_00287 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MPDNDLLC_00288 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MPDNDLLC_00289 6.6e-78 ureE O enzyme active site formation
MPDNDLLC_00290 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MPDNDLLC_00291 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MPDNDLLC_00292 3.4e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MPDNDLLC_00293 2.7e-177 cbiM P PDGLE domain
MPDNDLLC_00294 1.1e-136 P cobalt transport protein
MPDNDLLC_00295 1.6e-131 cbiO P ABC transporter
MPDNDLLC_00296 5.3e-153 ET amino acid transport
MPDNDLLC_00297 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPDNDLLC_00298 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
MPDNDLLC_00299 3.8e-205 EGP Transmembrane secretion effector
MPDNDLLC_00300 1.8e-153 ET amino acid transport
MPDNDLLC_00301 2.3e-162 metQ M Belongs to the NlpA lipoprotein family
MPDNDLLC_00302 2.5e-77 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MPDNDLLC_00303 4.8e-76 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MPDNDLLC_00304 2.1e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
MPDNDLLC_00305 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MPDNDLLC_00306 3e-98 metI P ABC transporter (Permease
MPDNDLLC_00307 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MPDNDLLC_00308 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MPDNDLLC_00309 8e-94 S UPF0397 protein
MPDNDLLC_00310 0.0 ykoD P abc transporter atp-binding protein
MPDNDLLC_00311 1.2e-146 cbiQ P cobalt transport
MPDNDLLC_00312 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MPDNDLLC_00313 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
MPDNDLLC_00314 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
MPDNDLLC_00315 1.2e-244 P COG0168 Trk-type K transport systems, membrane components
MPDNDLLC_00316 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
MPDNDLLC_00317 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
MPDNDLLC_00318 3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPDNDLLC_00319 4.1e-281 T PhoQ Sensor
MPDNDLLC_00320 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MPDNDLLC_00321 1.4e-217 dnaB L Replication initiation and membrane attachment
MPDNDLLC_00322 5.2e-167 dnaI L Primosomal protein DnaI
MPDNDLLC_00323 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MPDNDLLC_00325 1.2e-34
MPDNDLLC_00326 3e-27 L Integrase core domain protein
MPDNDLLC_00327 3.4e-50 L transposition
MPDNDLLC_00328 5.7e-23 L Transposase
MPDNDLLC_00329 7.8e-28 L transposase activity
MPDNDLLC_00330 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MPDNDLLC_00331 6.5e-63 manO S protein conserved in bacteria
MPDNDLLC_00332 1.1e-167 manN G PTS system mannose fructose sorbose family IID component
MPDNDLLC_00333 2.3e-116 manM G pts system
MPDNDLLC_00334 2.4e-181 manL 2.7.1.191 G pts system
MPDNDLLC_00335 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
MPDNDLLC_00336 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MPDNDLLC_00337 1.9e-248 pbuO S permease
MPDNDLLC_00338 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
MPDNDLLC_00339 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
MPDNDLLC_00340 1.2e-219 brpA K Transcriptional
MPDNDLLC_00341 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
MPDNDLLC_00342 3.1e-212 nusA K Participates in both transcription termination and antitermination
MPDNDLLC_00343 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
MPDNDLLC_00344 1.4e-41 ylxQ J ribosomal protein
MPDNDLLC_00345 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MPDNDLLC_00346 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MPDNDLLC_00347 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
MPDNDLLC_00348 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
MPDNDLLC_00349 8e-213 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
MPDNDLLC_00350 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MPDNDLLC_00351 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
MPDNDLLC_00352 6e-89 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
MPDNDLLC_00353 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
MPDNDLLC_00354 3.9e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MPDNDLLC_00356 1.4e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
MPDNDLLC_00357 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MPDNDLLC_00358 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MPDNDLLC_00359 1.2e-74 ylbF S Belongs to the UPF0342 family
MPDNDLLC_00360 7.1e-46 ylbG S UPF0298 protein
MPDNDLLC_00361 1e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MPDNDLLC_00362 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
MPDNDLLC_00363 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
MPDNDLLC_00364 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MPDNDLLC_00365 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MPDNDLLC_00366 2.8e-70 acuB S IMP dehydrogenase activity
MPDNDLLC_00367 3.3e-43 acuB S IMP dehydrogenase activity
MPDNDLLC_00368 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MPDNDLLC_00369 6.3e-111 yvyE 3.4.13.9 S YigZ family
MPDNDLLC_00370 6.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MPDNDLLC_00371 4.4e-123 comFC S Competence protein
MPDNDLLC_00372 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MPDNDLLC_00375 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
MPDNDLLC_00376 6.4e-108 S Domain of unknown function (DUF1803)
MPDNDLLC_00377 7.8e-102 ygaC J Belongs to the UPF0374 family
MPDNDLLC_00378 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
MPDNDLLC_00379 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MPDNDLLC_00380 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
MPDNDLLC_00381 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
MPDNDLLC_00382 4.3e-115 S Haloacid dehalogenase-like hydrolase
MPDNDLLC_00383 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MPDNDLLC_00384 4e-72 marR K Transcriptional regulator, MarR family
MPDNDLLC_00385 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MPDNDLLC_00386 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MPDNDLLC_00387 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
MPDNDLLC_00388 1.9e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MPDNDLLC_00389 1.6e-126 IQ reductase
MPDNDLLC_00390 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MPDNDLLC_00391 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MPDNDLLC_00392 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MPDNDLLC_00393 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MPDNDLLC_00394 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MPDNDLLC_00395 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MPDNDLLC_00396 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MPDNDLLC_00397 1.1e-65 tnp L Transposase
MPDNDLLC_00398 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
MPDNDLLC_00399 1.8e-84 L Transposase
MPDNDLLC_00400 5.6e-114 fruR K transcriptional
MPDNDLLC_00401 4.6e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MPDNDLLC_00402 2e-265 fruA 2.7.1.202 G phosphotransferase system
MPDNDLLC_00403 9.1e-35 fruA 2.7.1.202 G phosphotransferase system
MPDNDLLC_00404 7.9e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MPDNDLLC_00405 2.8e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MPDNDLLC_00407 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
MPDNDLLC_00408 1.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MPDNDLLC_00409 1.9e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MPDNDLLC_00410 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MPDNDLLC_00411 6.4e-29 2.3.1.128 K acetyltransferase
MPDNDLLC_00412 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MPDNDLLC_00413 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MPDNDLLC_00414 1.4e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MPDNDLLC_00415 2.6e-64 WQ51_03320 S cog cog4835
MPDNDLLC_00416 3.2e-60 XK27_08360 S EDD domain protein, DegV family
MPDNDLLC_00417 5.5e-75 XK27_08360 S EDD domain protein, DegV family
MPDNDLLC_00418 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MPDNDLLC_00419 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MPDNDLLC_00420 0.0 yfmR S abc transporter atp-binding protein
MPDNDLLC_00421 1.6e-24 U response to pH
MPDNDLLC_00422 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
MPDNDLLC_00423 3.8e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
MPDNDLLC_00424 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MPDNDLLC_00425 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MPDNDLLC_00426 1.9e-77 K DNA-binding transcription factor activity
MPDNDLLC_00427 0.0 lmrA1 V abc transporter atp-binding protein
MPDNDLLC_00428 0.0 lmrA2 V abc transporter atp-binding protein
MPDNDLLC_00429 5.4e-45 K Acetyltransferase (GNAT) family
MPDNDLLC_00430 3.2e-78 sptS 2.7.13.3 T Histidine kinase
MPDNDLLC_00431 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MPDNDLLC_00432 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MPDNDLLC_00433 5.3e-161 cvfB S Protein conserved in bacteria
MPDNDLLC_00434 7.4e-35 yozE S Belongs to the UPF0346 family
MPDNDLLC_00435 1.6e-84 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
MPDNDLLC_00436 3.7e-54 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
MPDNDLLC_00437 2.3e-61 rlpA M LysM domain protein
MPDNDLLC_00438 8e-191 phoH T phosphate starvation-inducible protein PhoH
MPDNDLLC_00442 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MPDNDLLC_00443 1.8e-164 K transcriptional regulator (lysR family)
MPDNDLLC_00444 1.4e-186 coiA 3.6.4.12 S Competence protein
MPDNDLLC_00445 0.0 pepF E oligoendopeptidase F
MPDNDLLC_00446 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
MPDNDLLC_00447 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
MPDNDLLC_00448 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MPDNDLLC_00449 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MPDNDLLC_00450 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MPDNDLLC_00451 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
MPDNDLLC_00452 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
MPDNDLLC_00453 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MPDNDLLC_00454 3.5e-227 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
MPDNDLLC_00455 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MPDNDLLC_00456 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MPDNDLLC_00457 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MPDNDLLC_00458 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MPDNDLLC_00459 4.1e-132 yxkH G deacetylase
MPDNDLLC_00460 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MPDNDLLC_00461 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MPDNDLLC_00462 5.5e-153 rarD S Transporter
MPDNDLLC_00463 2.2e-15 T peptidase
MPDNDLLC_00464 8.9e-14 coiA 3.6.4.12 S Competence protein
MPDNDLLC_00465 5.6e-109 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MPDNDLLC_00466 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MPDNDLLC_00467 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MPDNDLLC_00468 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MPDNDLLC_00469 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
MPDNDLLC_00470 3.3e-78 atpF C ATP synthase F(0) sector subunit b
MPDNDLLC_00471 6e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MPDNDLLC_00472 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MPDNDLLC_00473 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MPDNDLLC_00474 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MPDNDLLC_00475 1.3e-65 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MPDNDLLC_00476 2.8e-230 ftsW D Belongs to the SEDS family
MPDNDLLC_00477 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MPDNDLLC_00478 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MPDNDLLC_00479 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MPDNDLLC_00480 6.4e-162 holB 2.7.7.7 L dna polymerase iii
MPDNDLLC_00481 3.1e-134 yaaT S stage 0 sporulation protein
MPDNDLLC_00482 9.5e-55 yabA L Involved in initiation control of chromosome replication
MPDNDLLC_00483 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MPDNDLLC_00484 2.6e-233 amt P Ammonium Transporter
MPDNDLLC_00485 1.1e-53 glnB K Belongs to the P(II) protein family
MPDNDLLC_00486 4.9e-106 mur1 NU mannosyl-glycoprotein
MPDNDLLC_00487 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
MPDNDLLC_00488 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
MPDNDLLC_00489 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MPDNDLLC_00490 1.8e-53
MPDNDLLC_00491 7.5e-26
MPDNDLLC_00492 1.5e-59
MPDNDLLC_00493 6.1e-63 S membrane
MPDNDLLC_00494 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MPDNDLLC_00495 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MPDNDLLC_00496 4.5e-39 ynzC S UPF0291 protein
MPDNDLLC_00497 3.9e-254 cycA E permease
MPDNDLLC_00498 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
MPDNDLLC_00499 1.7e-70 pts33BCA G pts system
MPDNDLLC_00500 1.1e-76 pts33BCA G pts system
MPDNDLLC_00501 5.5e-84 pts33BCA G pts system
MPDNDLLC_00502 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MPDNDLLC_00503 1.2e-165 L integrase core domain
MPDNDLLC_00504 1.1e-121 L Transposase
MPDNDLLC_00509 1.4e-167 fhuR K transcriptional regulator (lysR family)
MPDNDLLC_00510 1.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MPDNDLLC_00511 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MPDNDLLC_00512 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MPDNDLLC_00513 4.9e-227 pyrP F uracil Permease
MPDNDLLC_00514 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MPDNDLLC_00515 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
MPDNDLLC_00516 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
MPDNDLLC_00517 2.1e-238 L Transposase
MPDNDLLC_00518 7.1e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
MPDNDLLC_00519 5.3e-22 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPDNDLLC_00520 3.6e-32 V efflux transmembrane transporter activity
MPDNDLLC_00521 7e-27 ytrF V efflux transmembrane transporter activity
MPDNDLLC_00522 1.3e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MPDNDLLC_00523 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MPDNDLLC_00524 3.4e-189 L Transposase
MPDNDLLC_00525 1.6e-18 L Integrase core domain
MPDNDLLC_00526 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
MPDNDLLC_00527 1.5e-48 hrtB V ABC transporter (Permease
MPDNDLLC_00528 3.6e-165 L integrase core domain
MPDNDLLC_00529 1.1e-121 L Transposase
MPDNDLLC_00530 5.7e-105 hrtB V MacB-like periplasmic core domain
MPDNDLLC_00533 3.4e-91 S MucBP domain
MPDNDLLC_00534 1.9e-49 M YSIRK type signal peptide
MPDNDLLC_00535 0.0 M the current gene model (or a revised gene model) may contain a
MPDNDLLC_00537 0.0 mdlB V abc transporter atp-binding protein
MPDNDLLC_00538 0.0 lmrA V abc transporter atp-binding protein
MPDNDLLC_00539 6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MPDNDLLC_00540 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MPDNDLLC_00541 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
MPDNDLLC_00542 2.5e-132 rr02 KT response regulator
MPDNDLLC_00543 1.7e-173 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MPDNDLLC_00544 2.1e-34 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MPDNDLLC_00545 2.8e-168 V ABC transporter
MPDNDLLC_00546 5.4e-122 sagI S ABC-2 type transporter
MPDNDLLC_00547 6.9e-197 yceA S Belongs to the UPF0176 family
MPDNDLLC_00548 8e-28 XK27_00085 K Transcriptional
MPDNDLLC_00549 1.9e-22
MPDNDLLC_00550 1.4e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
MPDNDLLC_00551 2.5e-113 S VIT family
MPDNDLLC_00552 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MPDNDLLC_00553 2.4e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MPDNDLLC_00554 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
MPDNDLLC_00555 3.8e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MPDNDLLC_00556 1.3e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MPDNDLLC_00557 8.8e-104 GBS0088 J protein conserved in bacteria
MPDNDLLC_00558 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MPDNDLLC_00559 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MPDNDLLC_00560 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
MPDNDLLC_00561 2e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MPDNDLLC_00562 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MPDNDLLC_00563 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
MPDNDLLC_00564 2.5e-21
MPDNDLLC_00565 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MPDNDLLC_00567 3.5e-07 U protein secretion
MPDNDLLC_00568 2.1e-50 U protein secretion
MPDNDLLC_00569 1.1e-11 U protein secretion
MPDNDLLC_00570 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
MPDNDLLC_00571 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MPDNDLLC_00572 4.9e-21 XK27_13030
MPDNDLLC_00573 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MPDNDLLC_00574 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MPDNDLLC_00575 9.8e-163 S Protein of unknown function (DUF3114)
MPDNDLLC_00576 1.2e-22 S Protein of unknown function (DUF3114)
MPDNDLLC_00577 1.5e-118 yqfA K protein, Hemolysin III
MPDNDLLC_00578 1e-25 K hmm pf08876
MPDNDLLC_00579 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MPDNDLLC_00580 1.7e-218 mvaS 2.3.3.10 I synthase
MPDNDLLC_00581 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MPDNDLLC_00582 2.2e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MPDNDLLC_00583 9.7e-22
MPDNDLLC_00584 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MPDNDLLC_00585 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
MPDNDLLC_00586 1.5e-250 mmuP E amino acid
MPDNDLLC_00587 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
MPDNDLLC_00588 1.4e-29 S Domain of unknown function (DUF1912)
MPDNDLLC_00589 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
MPDNDLLC_00590 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MPDNDLLC_00591 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MPDNDLLC_00592 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MPDNDLLC_00593 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
MPDNDLLC_00594 4.8e-16 S Protein of unknown function (DUF2969)
MPDNDLLC_00597 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
MPDNDLLC_00600 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
MPDNDLLC_00601 6.1e-70 M Pfam SNARE associated Golgi protein
MPDNDLLC_00602 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
MPDNDLLC_00603 9.3e-59 S oxidoreductase
MPDNDLLC_00604 9.7e-66 S oxidoreductase
MPDNDLLC_00605 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
MPDNDLLC_00606 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MPDNDLLC_00607 0.0 clpE O Belongs to the ClpA ClpB family
MPDNDLLC_00608 6.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MPDNDLLC_00609 1.3e-34 ykuJ S protein conserved in bacteria
MPDNDLLC_00610 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
MPDNDLLC_00611 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
MPDNDLLC_00612 1.1e-78 feoA P FeoA domain protein
MPDNDLLC_00613 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MPDNDLLC_00614 6.6e-08
MPDNDLLC_00615 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MPDNDLLC_00616 2.2e-45 K sequence-specific DNA binding
MPDNDLLC_00617 1.5e-35 yugF I carboxylic ester hydrolase activity
MPDNDLLC_00618 7.5e-23 I Alpha/beta hydrolase family
MPDNDLLC_00619 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MPDNDLLC_00620 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MPDNDLLC_00621 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
MPDNDLLC_00622 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MPDNDLLC_00623 4.3e-37 licT K transcriptional antiterminator
MPDNDLLC_00624 1.8e-64 licT K antiterminator
MPDNDLLC_00625 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MPDNDLLC_00626 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MPDNDLLC_00627 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MPDNDLLC_00628 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MPDNDLLC_00629 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MPDNDLLC_00630 2.9e-221 mdtG EGP Major facilitator Superfamily
MPDNDLLC_00631 2e-33 secG U Preprotein translocase subunit SecG
MPDNDLLC_00632 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MPDNDLLC_00633 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MPDNDLLC_00634 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MPDNDLLC_00635 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
MPDNDLLC_00636 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
MPDNDLLC_00637 4.4e-183 ccpA K Catabolite control protein A
MPDNDLLC_00638 1.5e-26 yyaQ S YjbR
MPDNDLLC_00639 6.6e-101 yyaQ V Protein conserved in bacteria
MPDNDLLC_00640 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MPDNDLLC_00641 2e-74 yueI S Protein of unknown function (DUF1694)
MPDNDLLC_00642 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MPDNDLLC_00644 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MPDNDLLC_00645 2e-219 ywbD 2.1.1.191 J Methyltransferase
MPDNDLLC_00646 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MPDNDLLC_00647 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MPDNDLLC_00648 1.3e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MPDNDLLC_00649 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MPDNDLLC_00650 8.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MPDNDLLC_00651 3.2e-53 yheA S Belongs to the UPF0342 family
MPDNDLLC_00652 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MPDNDLLC_00653 2.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MPDNDLLC_00654 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MPDNDLLC_00655 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
MPDNDLLC_00656 7.1e-251 msrR K Transcriptional regulator
MPDNDLLC_00657 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
MPDNDLLC_00658 2.4e-203 I acyl-CoA dehydrogenase
MPDNDLLC_00659 4.5e-97 mip S hydroperoxide reductase activity
MPDNDLLC_00660 8e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MPDNDLLC_00661 2.4e-50 J Acetyltransferase (GNAT) domain
MPDNDLLC_00662 5.7e-95
MPDNDLLC_00663 5.8e-194 L Transposase
MPDNDLLC_00664 1.5e-37 L transposase activity
MPDNDLLC_00665 3.2e-66 L COG2801 Transposase and inactivated derivatives
MPDNDLLC_00666 1.2e-73 L COG2801 Transposase and inactivated derivatives
MPDNDLLC_00667 8.9e-11
MPDNDLLC_00668 7.8e-59 S Protein of unknown function (DUF1722)
MPDNDLLC_00669 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
MPDNDLLC_00671 1.2e-32
MPDNDLLC_00672 1.7e-26 S CAAX protease self-immunity
MPDNDLLC_00673 5.5e-42 S CAAX protease self-immunity
MPDNDLLC_00674 5.6e-27 estA E GDSL-like Lipase/Acylhydrolase
MPDNDLLC_00675 2.1e-95
MPDNDLLC_00676 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MPDNDLLC_00677 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MPDNDLLC_00678 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MPDNDLLC_00679 1e-185 S CRISPR-associated protein Csn2 subfamily St
MPDNDLLC_00680 1.3e-148 ycgQ S TIGR03943 family
MPDNDLLC_00681 5.4e-156 XK27_03015 S permease
MPDNDLLC_00683 0.0 yhgF K Transcriptional accessory protein
MPDNDLLC_00684 9.9e-42 pspC KT PspC domain
MPDNDLLC_00685 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MPDNDLLC_00686 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MPDNDLLC_00688 5.5e-69 ytxH S General stress protein
MPDNDLLC_00690 2e-177 yegQ O Peptidase U32
MPDNDLLC_00691 3.4e-252 yegQ O Peptidase U32
MPDNDLLC_00692 8.1e-46 S CHY zinc finger
MPDNDLLC_00693 8.4e-88 bioY S biotin synthase
MPDNDLLC_00695 1.1e-33 XK27_12190 S protein conserved in bacteria
MPDNDLLC_00696 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
MPDNDLLC_00698 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
MPDNDLLC_00699 0.0 L helicase
MPDNDLLC_00700 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MPDNDLLC_00701 1e-163 M LysM domain
MPDNDLLC_00702 7.6e-16
MPDNDLLC_00703 7.5e-174 S hydrolase
MPDNDLLC_00704 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MPDNDLLC_00705 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MPDNDLLC_00706 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
MPDNDLLC_00707 2.7e-27 P Hemerythrin HHE cation binding domain protein
MPDNDLLC_00708 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPDNDLLC_00709 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
MPDNDLLC_00710 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
MPDNDLLC_00711 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
MPDNDLLC_00712 1.4e-287 hsdM 2.1.1.72 V N-6 DNA Methylase
MPDNDLLC_00713 1.2e-139 3.1.21.3 V type I restriction modification DNA specificity domain
MPDNDLLC_00715 2.5e-44
MPDNDLLC_00716 3.9e-38
MPDNDLLC_00717 3.3e-170 spd F DNA RNA non-specific endonuclease
MPDNDLLC_00718 3.6e-35 V efflux transmembrane transporter activity
MPDNDLLC_00719 3.1e-31 V efflux transmembrane transporter activity
MPDNDLLC_00720 8.2e-28 ytrF V efflux transmembrane transporter activity
MPDNDLLC_00721 1.3e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MPDNDLLC_00722 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MPDNDLLC_00723 6.5e-94 L Transposase
MPDNDLLC_00724 1.5e-110 L Transposase
MPDNDLLC_00725 1e-119 L Integrase core domain
MPDNDLLC_00726 5.6e-133 L Transposase and inactivated derivatives
MPDNDLLC_00727 1.1e-44 L COG2963 Transposase and inactivated derivatives
MPDNDLLC_00728 0.0 lptA M Putative Ig domain
MPDNDLLC_00729 2e-91 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
MPDNDLLC_00730 6.5e-84 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
MPDNDLLC_00731 3.6e-09
MPDNDLLC_00732 3e-57
MPDNDLLC_00733 6.8e-57 S Bacterial mobilisation protein (MobC)
MPDNDLLC_00734 9.7e-301 U relaxase
MPDNDLLC_00735 1.7e-221 L Transposase
MPDNDLLC_00736 3.5e-258 mdlB V abc transporter atp-binding protein
MPDNDLLC_00737 2e-46 mdlB V abc transporter atp-binding protein
MPDNDLLC_00738 0.0 lmrA V abc transporter atp-binding protein
MPDNDLLC_00739 6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MPDNDLLC_00740 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MPDNDLLC_00741 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
MPDNDLLC_00742 2.5e-132 rr02 KT response regulator
MPDNDLLC_00743 1.7e-173 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MPDNDLLC_00744 2.1e-34 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MPDNDLLC_00745 2.8e-168 V ABC transporter
MPDNDLLC_00746 5.4e-122 sagI S ABC-2 type transporter
MPDNDLLC_00747 1e-195 yceA S Belongs to the UPF0176 family
MPDNDLLC_00748 1.2e-26 XK27_00085 K Transcriptional
MPDNDLLC_00749 4.3e-22
MPDNDLLC_00750 1.7e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
MPDNDLLC_00751 2.5e-113 S VIT family
MPDNDLLC_00752 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MPDNDLLC_00753 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MPDNDLLC_00754 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
MPDNDLLC_00755 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MPDNDLLC_00756 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MPDNDLLC_00757 2.2e-99 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MPDNDLLC_00758 8.9e-20
MPDNDLLC_00759 3.2e-46
MPDNDLLC_00760 1e-31 K Cro/C1-type HTH DNA-binding domain
MPDNDLLC_00761 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MPDNDLLC_00762 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
MPDNDLLC_00763 3.1e-94
MPDNDLLC_00764 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MPDNDLLC_00765 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MPDNDLLC_00766 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MPDNDLLC_00767 9e-195 S CRISPR-associated protein Csn2 subfamily St
MPDNDLLC_00768 4.7e-23 MA20_36090 S Protein of unknown function (DUF2974)
MPDNDLLC_00770 2.5e-103 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MPDNDLLC_00771 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MPDNDLLC_00772 1.4e-68
MPDNDLLC_00774 5.3e-08
MPDNDLLC_00775 2.8e-131 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MPDNDLLC_00776 0.0 S KAP family P-loop domain
MPDNDLLC_00777 3e-131 S Protein conserved in bacteria
MPDNDLLC_00778 9.6e-305 hsdM 2.1.1.72 V type I restriction-modification system
MPDNDLLC_00780 4.8e-61 spd F DNA RNA non-specific endonuclease
MPDNDLLC_00781 5.3e-91 spd F DNA RNA non-specific endonuclease
MPDNDLLC_00782 3.4e-92 lemA S LemA family
MPDNDLLC_00783 3.2e-132 htpX O Belongs to the peptidase M48B family
MPDNDLLC_00784 4.2e-75 S Psort location CytoplasmicMembrane, score
MPDNDLLC_00785 6.2e-56 S Domain of unknown function (DUF4430)
MPDNDLLC_00786 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MPDNDLLC_00787 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
MPDNDLLC_00788 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
MPDNDLLC_00789 2e-186 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
MPDNDLLC_00790 2.2e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MPDNDLLC_00791 3.5e-91 dps P Belongs to the Dps family
MPDNDLLC_00792 1.1e-80 perR P Belongs to the Fur family
MPDNDLLC_00793 8.4e-28 yqgQ S protein conserved in bacteria
MPDNDLLC_00794 2.2e-179 glk 2.7.1.2 G Glucokinase
MPDNDLLC_00795 0.0 typA T GTP-binding protein TypA
MPDNDLLC_00797 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MPDNDLLC_00798 5e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MPDNDLLC_00799 3.1e-169 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MPDNDLLC_00800 4.4e-250 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MPDNDLLC_00801 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MPDNDLLC_00802 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MPDNDLLC_00803 6.8e-96 sepF D cell septum assembly
MPDNDLLC_00804 2.6e-34 yggT D integral membrane protein
MPDNDLLC_00805 1.2e-143 ylmH T S4 RNA-binding domain
MPDNDLLC_00806 1.8e-135 divIVA D Cell division protein DivIVA
MPDNDLLC_00807 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MPDNDLLC_00808 5.5e-30
MPDNDLLC_00809 8.4e-10
MPDNDLLC_00810 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
MPDNDLLC_00811 2e-45 rpmE2 J 50S ribosomal protein L31
MPDNDLLC_00812 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MPDNDLLC_00813 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
MPDNDLLC_00814 8.9e-155 gst O Glutathione S-transferase
MPDNDLLC_00815 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MPDNDLLC_00816 2.4e-112 tdk 2.7.1.21 F thymidine kinase
MPDNDLLC_00817 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MPDNDLLC_00818 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MPDNDLLC_00819 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MPDNDLLC_00820 3.1e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MPDNDLLC_00821 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
MPDNDLLC_00822 6.6e-105 pvaA M lytic transglycosylase activity
MPDNDLLC_00823 0.0 yfiB1 V abc transporter atp-binding protein
MPDNDLLC_00824 0.0 XK27_10035 V abc transporter atp-binding protein
MPDNDLLC_00825 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
MPDNDLLC_00826 6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPDNDLLC_00827 1.6e-235 dltB M Membrane protein involved in D-alanine export
MPDNDLLC_00828 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPDNDLLC_00829 1.3e-227 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MPDNDLLC_00830 2.1e-238 L Transposase
MPDNDLLC_00831 9.8e-32 L Integrase core domain protein
MPDNDLLC_00832 9.6e-32 L transposition
MPDNDLLC_00833 6.5e-54 L transposition
MPDNDLLC_00834 7.7e-19 L transposase activity
MPDNDLLC_00835 0.0 3.6.3.8 P cation transport ATPase
MPDNDLLC_00836 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
MPDNDLLC_00838 2.9e-12
MPDNDLLC_00840 4.3e-67 S Virulence-associated protein E
MPDNDLLC_00841 1.4e-129 KL Phage plasmid primase P4 family
MPDNDLLC_00842 3.1e-22
MPDNDLLC_00843 1.4e-13
MPDNDLLC_00847 1.8e-19 K Cro/C1-type HTH DNA-binding domain
MPDNDLLC_00848 1e-21 xre K transcriptional
MPDNDLLC_00849 5.8e-219 sip L Belongs to the 'phage' integrase family
MPDNDLLC_00851 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MPDNDLLC_00852 7.3e-166 metF 1.5.1.20 E reductase
MPDNDLLC_00853 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MPDNDLLC_00854 1.7e-94 panT S ECF transporter, substrate-specific component
MPDNDLLC_00855 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MPDNDLLC_00856 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
MPDNDLLC_00857 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MPDNDLLC_00858 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPDNDLLC_00859 2.8e-40 T PhoQ Sensor
MPDNDLLC_00860 2.2e-43 T PhoQ Sensor
MPDNDLLC_00861 3.6e-88 T PhoQ Sensor
MPDNDLLC_00862 3.9e-122 L Transposase
MPDNDLLC_00863 1.2e-165 L integrase core domain
MPDNDLLC_00864 1.1e-220 L Transposase
MPDNDLLC_00865 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
MPDNDLLC_00866 8.9e-206 potD P spermidine putrescine ABC transporter
MPDNDLLC_00867 3.1e-268 clcA P Chloride transporter, ClC family
MPDNDLLC_00868 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
MPDNDLLC_00869 1.9e-21 L Helix-turn-helix domain
MPDNDLLC_00870 1.1e-82 L Helix-turn-helix domain
MPDNDLLC_00871 9.8e-163 L Integrase core domain protein
MPDNDLLC_00872 1.6e-249 L Transposase
MPDNDLLC_00873 2.1e-30 rpsT J rRNA binding
MPDNDLLC_00874 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
MPDNDLLC_00875 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
MPDNDLLC_00876 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MPDNDLLC_00877 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MPDNDLLC_00878 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MPDNDLLC_00879 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MPDNDLLC_00880 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MPDNDLLC_00881 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MPDNDLLC_00882 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MPDNDLLC_00883 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
MPDNDLLC_00884 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
MPDNDLLC_00885 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MPDNDLLC_00886 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MPDNDLLC_00887 3.1e-81 ypmB S Protein conserved in bacteria
MPDNDLLC_00888 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MPDNDLLC_00889 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MPDNDLLC_00890 1.5e-07
MPDNDLLC_00891 2.4e-30
MPDNDLLC_00892 3e-13
MPDNDLLC_00893 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
MPDNDLLC_00894 1.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MPDNDLLC_00895 3.7e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MPDNDLLC_00896 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MPDNDLLC_00897 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
MPDNDLLC_00898 2.2e-19 D nuclear chromosome segregation
MPDNDLLC_00899 2.8e-137 yejC S cyclic nucleotide-binding protein
MPDNDLLC_00900 1.2e-163 rapZ S Displays ATPase and GTPase activities
MPDNDLLC_00901 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MPDNDLLC_00902 8.7e-162 whiA K May be required for sporulation
MPDNDLLC_00903 6.4e-168 pepD E Dipeptidase
MPDNDLLC_00904 5.4e-32 cspD K Cold shock protein domain
MPDNDLLC_00905 8e-42 K Cold-Shock Protein
MPDNDLLC_00906 1.1e-31 L Transposase
MPDNDLLC_00907 1.7e-176 L Transposase
MPDNDLLC_00908 0.0 copB 3.6.3.4 P P-type ATPase
MPDNDLLC_00909 4.1e-220 L Transposase
MPDNDLLC_00910 2.9e-190 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MPDNDLLC_00911 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MPDNDLLC_00912 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MPDNDLLC_00913 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
MPDNDLLC_00914 2.9e-32 L Transposase
MPDNDLLC_00915 1.2e-12 L Transposase
MPDNDLLC_00916 2.3e-150 L Transposase
MPDNDLLC_00917 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
MPDNDLLC_00918 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
MPDNDLLC_00919 3.7e-157 glcU U Glucose uptake
MPDNDLLC_00920 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
MPDNDLLC_00921 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
MPDNDLLC_00922 5.5e-100 XK27_10720 D peptidase activity
MPDNDLLC_00923 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
MPDNDLLC_00924 1.7e-08
MPDNDLLC_00926 1.2e-172 yeiH S Membrane
MPDNDLLC_00927 1.9e-119 mur1 NU muramidase
MPDNDLLC_00928 2.4e-83 L transposition
MPDNDLLC_00929 4.5e-166 cpsY K Transcriptional regulator
MPDNDLLC_00930 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MPDNDLLC_00931 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
MPDNDLLC_00932 2e-104 artQ P ABC transporter (Permease
MPDNDLLC_00933 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
MPDNDLLC_00934 5.5e-158 aatB ET ABC transporter substrate-binding protein
MPDNDLLC_00935 2.1e-73 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPDNDLLC_00936 7.4e-106 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPDNDLLC_00937 2.1e-07
MPDNDLLC_00938 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
MPDNDLLC_00939 1.9e-110 adhP 1.1.1.1 C alcohol dehydrogenase
MPDNDLLC_00940 4.6e-78 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
MPDNDLLC_00941 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MPDNDLLC_00942 2e-126 gntR1 K transcriptional
MPDNDLLC_00943 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MPDNDLLC_00944 6.1e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MPDNDLLC_00945 3.1e-87 niaX
MPDNDLLC_00946 7.8e-91 niaR S small molecule binding protein (contains 3H domain)
MPDNDLLC_00947 1.6e-128 K DNA-binding helix-turn-helix protein
MPDNDLLC_00948 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MPDNDLLC_00949 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MPDNDLLC_00950 8.2e-168 GK ROK family
MPDNDLLC_00951 2.4e-158 dprA LU DNA protecting protein DprA
MPDNDLLC_00952 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MPDNDLLC_00953 1.4e-150 S TraX protein
MPDNDLLC_00954 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPDNDLLC_00955 9e-251 T PhoQ Sensor
MPDNDLLC_00956 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MPDNDLLC_00957 5.4e-153 XK27_05470 E Methionine synthase
MPDNDLLC_00958 2.3e-13 XK27_05470 E Methionine synthase
MPDNDLLC_00959 5e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MPDNDLLC_00960 1.8e-25 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MPDNDLLC_00961 1.5e-43 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MPDNDLLC_00962 2.9e-92 ET Bacterial periplasmic substrate-binding proteins
MPDNDLLC_00963 4.7e-52 IQ Acetoin reductase
MPDNDLLC_00964 3.9e-19 IQ Acetoin reductase
MPDNDLLC_00965 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MPDNDLLC_00966 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MPDNDLLC_00970 1.1e-212 pqqE C radical SAM domain protein
MPDNDLLC_00971 4.4e-135 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
MPDNDLLC_00972 6.6e-61 EGP Major facilitator Superfamily
MPDNDLLC_00973 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MPDNDLLC_00974 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MPDNDLLC_00975 6e-36 L Transposase
MPDNDLLC_00976 6.4e-104 V ABC transporter (Permease
MPDNDLLC_00977 4.5e-113 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MPDNDLLC_00978 1.6e-10
MPDNDLLC_00979 9e-98 K Transcriptional regulator, TetR family
MPDNDLLC_00980 1.8e-159 czcD P cation diffusion facilitator family transporter
MPDNDLLC_00981 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MPDNDLLC_00982 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
MPDNDLLC_00983 6e-08 S Hydrolases of the alpha beta superfamily
MPDNDLLC_00984 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
MPDNDLLC_00985 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
MPDNDLLC_00988 1.2e-143 2.4.2.3 F Phosphorylase superfamily
MPDNDLLC_00989 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
MPDNDLLC_00990 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
MPDNDLLC_00991 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
MPDNDLLC_00992 6.3e-12 dinF V Mate efflux family protein
MPDNDLLC_00994 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MPDNDLLC_00995 1.8e-88 S TraX protein
MPDNDLLC_00996 1.7e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
MPDNDLLC_00997 8.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MPDNDLLC_00998 8.5e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MPDNDLLC_00999 6e-188 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MPDNDLLC_01000 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MPDNDLLC_01001 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
MPDNDLLC_01002 0.0 csm1 S CRISPR-associated protein Csm1 family
MPDNDLLC_01003 2.5e-62 csm2 L Csm2 Type III-A
MPDNDLLC_01004 1.6e-117 csm3 L RAMP superfamily
MPDNDLLC_01005 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
MPDNDLLC_01006 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
MPDNDLLC_01008 9.5e-32 csm6 S Psort location Cytoplasmic, score
MPDNDLLC_01009 8e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MPDNDLLC_01010 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MPDNDLLC_01012 2e-46 nylA 3.5.1.4 J Belongs to the amidase family
MPDNDLLC_01014 7.9e-266 dtpT E transporter
MPDNDLLC_01015 1.4e-62 yecS P ABC transporter (Permease
MPDNDLLC_01016 2.3e-20 yecS P amino acid transport
MPDNDLLC_01018 2e-272 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MPDNDLLC_01019 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
MPDNDLLC_01020 1.4e-104 yfiF3 K sequence-specific DNA binding
MPDNDLLC_01021 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MPDNDLLC_01022 1.8e-240 agcS E (Alanine) symporter
MPDNDLLC_01023 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MPDNDLLC_01024 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
MPDNDLLC_01025 1.8e-59 Q phosphatase activity
MPDNDLLC_01026 9.3e-62 S haloacid dehalogenase-like hydrolase
MPDNDLLC_01027 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MPDNDLLC_01028 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
MPDNDLLC_01029 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
MPDNDLLC_01030 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
MPDNDLLC_01031 3.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MPDNDLLC_01032 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MPDNDLLC_01033 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MPDNDLLC_01034 1.9e-43 yktA S Belongs to the UPF0223 family
MPDNDLLC_01035 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MPDNDLLC_01036 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MPDNDLLC_01037 3.3e-158 pstS P phosphate
MPDNDLLC_01038 4.7e-155 pstC P probably responsible for the translocation of the substrate across the membrane
MPDNDLLC_01039 1.2e-155 pstA P phosphate transport system permease
MPDNDLLC_01040 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MPDNDLLC_01041 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MPDNDLLC_01042 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
MPDNDLLC_01043 0.0 pepN 3.4.11.2 E aminopeptidase
MPDNDLLC_01044 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MPDNDLLC_01045 1.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
MPDNDLLC_01046 1.1e-17
MPDNDLLC_01047 3.7e-09
MPDNDLLC_01048 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MPDNDLLC_01049 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
MPDNDLLC_01050 2.3e-23 L Transposase
MPDNDLLC_01051 4.6e-25 tatA U protein secretion
MPDNDLLC_01052 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MPDNDLLC_01053 8.8e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
MPDNDLLC_01054 5.6e-233 ycdB P peroxidase
MPDNDLLC_01055 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
MPDNDLLC_01056 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
MPDNDLLC_01057 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
MPDNDLLC_01058 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPDNDLLC_01059 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPDNDLLC_01060 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01061 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01062 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01063 6.1e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01064 4.4e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01065 5.8e-112 3.5.1.28 M GBS Bsp-like repeat
MPDNDLLC_01066 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MPDNDLLC_01067 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MPDNDLLC_01068 0.0 lpdA 1.8.1.4 C Dehydrogenase
MPDNDLLC_01069 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MPDNDLLC_01070 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MPDNDLLC_01071 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MPDNDLLC_01072 3.1e-45 hpk9 2.7.13.3 T protein histidine kinase activity
MPDNDLLC_01073 2.2e-83 2.7.13.3 T protein histidine kinase activity
MPDNDLLC_01074 3.6e-37 2.7.13.3 T protein histidine kinase activity
MPDNDLLC_01075 1.6e-52 2.7.13.3 T protein histidine kinase activity
MPDNDLLC_01076 1.3e-160 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
MPDNDLLC_01077 5.8e-169 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MPDNDLLC_01078 3.2e-110 casE S CRISPR system CASCADE complex protein CasE
MPDNDLLC_01079 3.6e-134 casD S CRISPR system CASCADE complex protein CasD
MPDNDLLC_01080 5.8e-181 casC L CT1975-like protein
MPDNDLLC_01081 6e-103 casB S CRISPR system CASCADE complex protein CasB
MPDNDLLC_01082 5.7e-250 casA L the current gene model (or a revised gene model) may contain a frame shift
MPDNDLLC_01083 0.0 cas3 L CRISPR-associated helicase cas3
MPDNDLLC_01084 0.0 S the current gene model (or a revised gene model) may contain a frame shift
MPDNDLLC_01085 2.4e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MPDNDLLC_01086 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MPDNDLLC_01087 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MPDNDLLC_01088 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MPDNDLLC_01089 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
MPDNDLLC_01090 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
MPDNDLLC_01091 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
MPDNDLLC_01092 1.2e-157 rssA S Phospholipase, patatin family
MPDNDLLC_01093 6.7e-78 estA E GDSL-like protein
MPDNDLLC_01094 2.6e-15 estA E Lysophospholipase L1 and related esterases
MPDNDLLC_01095 1.4e-292 S unusual protein kinase
MPDNDLLC_01096 4.9e-39 S granule-associated protein
MPDNDLLC_01097 1.8e-30 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MPDNDLLC_01098 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
MPDNDLLC_01099 1.4e-98 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MPDNDLLC_01100 8.4e-27 bglH 3.2.1.86 GT1 G beta-glucosidase activity
MPDNDLLC_01101 1.7e-199 S hmm pf01594
MPDNDLLC_01102 3.1e-87 G Belongs to the phosphoglycerate mutase family
MPDNDLLC_01103 3.4e-87 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MPDNDLLC_01104 3.8e-94 V VanZ like family
MPDNDLLC_01105 1.1e-178 L Transposase
MPDNDLLC_01106 8.2e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
MPDNDLLC_01107 6e-20 epsU S Polysaccharide biosynthesis protein
MPDNDLLC_01108 1.4e-172 epsU S Polysaccharide biosynthesis protein
MPDNDLLC_01109 1.8e-238 cps1C S Polysaccharide biosynthesis protein
MPDNDLLC_01110 8.7e-88 2.7.8.12 GT2 M Glycosyltransferase like family 2
MPDNDLLC_01111 4.3e-22 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MPDNDLLC_01112 1.8e-32 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MPDNDLLC_01113 4.8e-102 M group 2 family protein
MPDNDLLC_01114 7.7e-100
MPDNDLLC_01115 1.2e-71 cps1D M Domain of unknown function (DUF4422)
MPDNDLLC_01116 5.6e-62 L Transposase DDE domain
MPDNDLLC_01117 2.7e-73 L Transposase DDE domain
MPDNDLLC_01118 2.7e-23 rgpAc GT4 M group 1 family protein
MPDNDLLC_01119 2.7e-255 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MPDNDLLC_01121 2.4e-111 cpsD D COG0489 ATPases involved in chromosome partitioning
MPDNDLLC_01122 2.3e-98 cps4C M biosynthesis protein
MPDNDLLC_01123 5.1e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
MPDNDLLC_01124 9.7e-256 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
MPDNDLLC_01125 4.3e-222 L Transposase
MPDNDLLC_01126 5.8e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
MPDNDLLC_01127 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
MPDNDLLC_01128 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
MPDNDLLC_01129 1.5e-44 clcA_2 P chloride
MPDNDLLC_01130 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MPDNDLLC_01131 8.1e-41 S Protein of unknown function (DUF1697)
MPDNDLLC_01132 3.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MPDNDLLC_01133 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MPDNDLLC_01135 5.7e-08 V Glucan-binding protein C
MPDNDLLC_01136 4e-21 V Glucan-binding protein C
MPDNDLLC_01137 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
MPDNDLLC_01138 2.4e-275 pepV 3.5.1.18 E Dipeptidase
MPDNDLLC_01139 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MPDNDLLC_01140 6.9e-86 XK27_03610 K Gnat family
MPDNDLLC_01141 9.1e-10 L COG1943 Transposase and inactivated derivatives
MPDNDLLC_01142 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MPDNDLLC_01143 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MPDNDLLC_01144 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MPDNDLLC_01145 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MPDNDLLC_01146 3.9e-15 M LysM domain
MPDNDLLC_01147 2.9e-90 ebsA S Family of unknown function (DUF5322)
MPDNDLLC_01148 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MPDNDLLC_01149 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MPDNDLLC_01150 4.9e-224 G COG0457 FOG TPR repeat
MPDNDLLC_01151 5.2e-175 yubA S permease
MPDNDLLC_01152 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
MPDNDLLC_01153 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MPDNDLLC_01154 2.5e-124 ftsE D cell division ATP-binding protein FtsE
MPDNDLLC_01155 3.7e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MPDNDLLC_01156 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MPDNDLLC_01157 4.3e-180 yjjH S Calcineurin-like phosphoesterase
MPDNDLLC_01158 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MPDNDLLC_01159 0.0 pacL 3.6.3.8 P cation transport ATPase
MPDNDLLC_01160 2.6e-67 ywiB S Domain of unknown function (DUF1934)
MPDNDLLC_01161 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
MPDNDLLC_01162 9.2e-147 yidA S hydrolases of the HAD superfamily
MPDNDLLC_01163 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
MPDNDLLC_01164 5e-35 F Protein of unknown function (DUF454)
MPDNDLLC_01165 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
MPDNDLLC_01166 3.8e-246 vicK 2.7.13.3 T Histidine kinase
MPDNDLLC_01167 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPDNDLLC_01168 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
MPDNDLLC_01169 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MPDNDLLC_01170 8e-115 gltJ P ABC transporter (Permease
MPDNDLLC_01171 4.2e-110 tcyB_2 P ABC transporter (permease)
MPDNDLLC_01172 1.4e-145 endA F DNA RNA non-specific endonuclease
MPDNDLLC_01173 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
MPDNDLLC_01174 9.4e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MPDNDLLC_01176 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MPDNDLLC_01177 2.2e-21 G Domain of unknown function (DUF4832)
MPDNDLLC_01178 8.4e-53 G Domain of unknown function (DUF4832)
MPDNDLLC_01179 1.5e-211 cotH M CotH kinase protein
MPDNDLLC_01180 2.3e-49 pelG S Putative exopolysaccharide Exporter (EPS-E)
MPDNDLLC_01181 3.8e-199 pelG M Putative exopolysaccharide Exporter (EPS-E)
MPDNDLLC_01182 4.3e-277 pelF GT4 M Domain of unknown function (DUF3492)
MPDNDLLC_01183 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
MPDNDLLC_01184 6.3e-168
MPDNDLLC_01185 0.0 5.1.3.2 GM Psort location CytoplasmicMembrane, score
MPDNDLLC_01186 1e-14 L Transposase
MPDNDLLC_01187 1.1e-145 cps2J S Polysaccharide biosynthesis protein
MPDNDLLC_01188 7.2e-25 M Glycosyl transferase, family 2
MPDNDLLC_01189 8.8e-34 M Glycosyl transferase, family 2
MPDNDLLC_01190 1.9e-75 M Glycosyltransferase sugar-binding region containing DXD motif
MPDNDLLC_01191 8.5e-13
MPDNDLLC_01192 2.2e-68 M Glycosyl transferase, family 2
MPDNDLLC_01193 1e-45 GT2 M Glycosyl transferase family 2
MPDNDLLC_01194 6.6e-58 pssE S Glycosyltransferase family 28 C-terminal domain
MPDNDLLC_01195 2e-82 cpsF M Oligosaccharide biosynthesis protein Alg14 like
MPDNDLLC_01196 7.3e-86 cpsE M Bacterial sugar transferase
MPDNDLLC_01197 1.1e-76 cpsE M Bacterial sugar transferase
MPDNDLLC_01198 3.2e-253 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MPDNDLLC_01199 8.5e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
MPDNDLLC_01200 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MPDNDLLC_01201 1.7e-173 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MPDNDLLC_01202 1.2e-294 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MPDNDLLC_01203 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MPDNDLLC_01204 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MPDNDLLC_01205 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
MPDNDLLC_01208 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MPDNDLLC_01209 2.1e-219 XK27_05110 P chloride
MPDNDLLC_01210 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
MPDNDLLC_01211 4.9e-282 clcA P Chloride transporter, ClC family
MPDNDLLC_01212 1e-75 fld C Flavodoxin
MPDNDLLC_01213 5.5e-14 XK27_08880
MPDNDLLC_01214 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
MPDNDLLC_01215 2e-151 estA CE1 S Putative esterase
MPDNDLLC_01216 1.8e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MPDNDLLC_01217 1.2e-135 XK27_08845 S abc transporter atp-binding protein
MPDNDLLC_01218 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
MPDNDLLC_01219 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
MPDNDLLC_01220 1.6e-16 S Domain of unknown function (DUF4649)
MPDNDLLC_01222 5.1e-44 Q the current gene model (or a revised gene model) may contain a frame shift
MPDNDLLC_01223 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
MPDNDLLC_01225 9.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
MPDNDLLC_01227 1.6e-249 L Transposase
MPDNDLLC_01228 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MPDNDLLC_01229 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MPDNDLLC_01230 0.0 dnaE 2.7.7.7 L DNA polymerase
MPDNDLLC_01231 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
MPDNDLLC_01232 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MPDNDLLC_01233 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MPDNDLLC_01234 3.3e-43 ysdA L Membrane
MPDNDLLC_01235 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MPDNDLLC_01236 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MPDNDLLC_01237 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MPDNDLLC_01238 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MPDNDLLC_01240 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MPDNDLLC_01241 1.7e-83 ypmS S Protein conserved in bacteria
MPDNDLLC_01242 3.9e-143 ypmR E lipolytic protein G-D-S-L family
MPDNDLLC_01243 3e-148 DegV S DegV family
MPDNDLLC_01244 9.9e-305 recN L May be involved in recombinational repair of damaged DNA
MPDNDLLC_01245 1.8e-72 argR K Regulates arginine biosynthesis genes
MPDNDLLC_01246 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MPDNDLLC_01247 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MPDNDLLC_01248 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
MPDNDLLC_01249 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MPDNDLLC_01252 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MPDNDLLC_01253 2.9e-125 dnaD
MPDNDLLC_01254 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MPDNDLLC_01255 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MPDNDLLC_01256 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
MPDNDLLC_01257 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MPDNDLLC_01258 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MPDNDLLC_01259 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MPDNDLLC_01260 1.6e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MPDNDLLC_01261 5.6e-240 rodA D Belongs to the SEDS family
MPDNDLLC_01262 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
MPDNDLLC_01263 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MPDNDLLC_01264 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MPDNDLLC_01265 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MPDNDLLC_01266 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MPDNDLLC_01267 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MPDNDLLC_01268 1.9e-231 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MPDNDLLC_01269 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MPDNDLLC_01270 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MPDNDLLC_01271 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MPDNDLLC_01273 1.4e-86 L Integrase core domain protein
MPDNDLLC_01274 1.1e-53 L transposition
MPDNDLLC_01275 1.8e-21 L Transposase
MPDNDLLC_01276 5.2e-36 L transposase activity
MPDNDLLC_01277 1.3e-22 XK27_08085
MPDNDLLC_01278 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MPDNDLLC_01279 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MPDNDLLC_01280 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MPDNDLLC_01281 1.1e-121 ylfI S tigr01906
MPDNDLLC_01282 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MPDNDLLC_01283 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
MPDNDLLC_01284 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MPDNDLLC_01287 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MPDNDLLC_01288 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MPDNDLLC_01289 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MPDNDLLC_01290 1.1e-206 yurR 1.4.5.1 E oxidoreductase
MPDNDLLC_01291 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
MPDNDLLC_01292 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MPDNDLLC_01293 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
MPDNDLLC_01294 1.7e-70 gtrA S GtrA-like protein
MPDNDLLC_01295 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MPDNDLLC_01296 6e-169 ybbR S Protein conserved in bacteria
MPDNDLLC_01297 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MPDNDLLC_01298 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
MPDNDLLC_01299 8.7e-150 cobQ S glutamine amidotransferase
MPDNDLLC_01300 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MPDNDLLC_01301 4.8e-131 pip 1.11.1.10 S Alpha beta hydrolase
MPDNDLLC_01302 0.0 uup S abc transporter atp-binding protein
MPDNDLLC_01303 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MPDNDLLC_01304 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
MPDNDLLC_01305 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MPDNDLLC_01306 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
MPDNDLLC_01307 4.1e-181 L Transposase
MPDNDLLC_01308 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MPDNDLLC_01309 7.9e-39 ptsH G phosphocarrier protein Hpr
MPDNDLLC_01310 5.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
MPDNDLLC_01311 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
MPDNDLLC_01312 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MPDNDLLC_01313 2.2e-34 nrdH O Glutaredoxin
MPDNDLLC_01314 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MPDNDLLC_01315 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MPDNDLLC_01317 4.2e-71 L Transposase (IS116 IS110 IS902 family)
MPDNDLLC_01318 1.2e-164 ypuA S secreted protein
MPDNDLLC_01319 3.7e-51 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
MPDNDLLC_01320 2.4e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
MPDNDLLC_01321 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MPDNDLLC_01322 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MPDNDLLC_01323 3.4e-258 noxE P NADH oxidase
MPDNDLLC_01324 1.9e-294 yfmM S abc transporter atp-binding protein
MPDNDLLC_01325 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
MPDNDLLC_01326 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MPDNDLLC_01327 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MPDNDLLC_01328 2e-86 S ECF-type riboflavin transporter, S component
MPDNDLLC_01330 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MPDNDLLC_01331 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
MPDNDLLC_01334 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MPDNDLLC_01335 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPDNDLLC_01336 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MPDNDLLC_01337 0.0 smc D Required for chromosome condensation and partitioning
MPDNDLLC_01338 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MPDNDLLC_01339 2.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MPDNDLLC_01340 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MPDNDLLC_01341 2.4e-92 pat 2.3.1.183 M acetyltransferase
MPDNDLLC_01342 1.1e-12
MPDNDLLC_01343 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MPDNDLLC_01344 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MPDNDLLC_01345 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
MPDNDLLC_01346 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
MPDNDLLC_01347 6.9e-30 sdaAA 4.3.1.17 E L-serine dehydratase
MPDNDLLC_01348 4e-102 sdaAA 4.3.1.17 E L-serine dehydratase
MPDNDLLC_01349 7.4e-26
MPDNDLLC_01350 1.1e-144 S ABC-2 family transporter protein
MPDNDLLC_01351 3.6e-97 S transport system, permease component
MPDNDLLC_01352 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPDNDLLC_01353 1.5e-192 desK 2.7.13.3 T Histidine kinase
MPDNDLLC_01354 3.1e-133 yvfS V ABC-2 type transporter
MPDNDLLC_01355 8.7e-159 XK27_09825 V abc transporter atp-binding protein
MPDNDLLC_01359 3.3e-212 EGP Major facilitator Superfamily
MPDNDLLC_01360 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
MPDNDLLC_01361 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
MPDNDLLC_01362 4.6e-42 3.6.1.55 F NUDIX domain
MPDNDLLC_01364 3.7e-122 S An automated process has identified a potential problem with this gene model
MPDNDLLC_01365 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
MPDNDLLC_01366 1.4e-15 liaI KT membrane
MPDNDLLC_01367 2.6e-30 liaI KT membrane
MPDNDLLC_01368 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
MPDNDLLC_01369 0.0 V ABC transporter (permease)
MPDNDLLC_01370 1.9e-133 macB2 V ABC transporter, ATP-binding protein
MPDNDLLC_01371 6.2e-166 T Histidine kinase
MPDNDLLC_01372 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPDNDLLC_01373 9.2e-66 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MPDNDLLC_01374 3.3e-69 pbuX F xanthine permease
MPDNDLLC_01375 5.9e-115 pbuX F xanthine permease
MPDNDLLC_01376 1.5e-247 norM V Multidrug efflux pump
MPDNDLLC_01377 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MPDNDLLC_01378 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
MPDNDLLC_01379 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
MPDNDLLC_01380 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
MPDNDLLC_01381 4.8e-25 csbD K CsbD-like
MPDNDLLC_01382 8.2e-228 yfnA E amino acid
MPDNDLLC_01383 1.8e-62 XK27_02070 S nitroreductase
MPDNDLLC_01384 2.4e-121 amiC P ABC transporter (Permease
MPDNDLLC_01385 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MPDNDLLC_01386 8.8e-223 L Transposase
MPDNDLLC_01387 1.4e-31 amiA E ABC transporter, substrate-binding protein, family 5
MPDNDLLC_01388 0.0 rgpF M Rhamnan synthesis protein F
MPDNDLLC_01389 1.1e-179 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MPDNDLLC_01390 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MPDNDLLC_01391 1.4e-142 rgpC GM Transport permease protein
MPDNDLLC_01392 1.4e-178 rgpB GT2 M Glycosyltransferase, group 2 family protein
MPDNDLLC_01393 1.2e-224 rgpA GT4 M Domain of unknown function (DUF1972)
MPDNDLLC_01394 6e-139 S Predicted membrane protein (DUF2142)
MPDNDLLC_01395 1.6e-127 2.7.8.12 M transferase activity, transferring glycosyl groups
MPDNDLLC_01396 1.8e-213 amrA S polysaccharide biosynthetic process
MPDNDLLC_01397 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
MPDNDLLC_01398 1.9e-124 ycbB S Glycosyl transferase family 2
MPDNDLLC_01399 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MPDNDLLC_01400 4.1e-245
MPDNDLLC_01401 6.7e-75 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MPDNDLLC_01402 6.8e-230 S dextransucrase activity
MPDNDLLC_01403 6.1e-146 S dextransucrase activity
MPDNDLLC_01404 1.6e-21 L Integrase core domain protein
MPDNDLLC_01407 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
MPDNDLLC_01408 3e-114 yxeN P ABC transporter, permease protein
MPDNDLLC_01409 6.1e-107 ytmL P ABC transporter (Permease
MPDNDLLC_01410 2.4e-161 ET ABC transporter substrate-binding protein
MPDNDLLC_01411 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
MPDNDLLC_01412 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MPDNDLLC_01413 2.4e-40 S Sugar efflux transporter for intercellular exchange
MPDNDLLC_01414 5.9e-23 P FtsX-like permease family
MPDNDLLC_01415 1.2e-90 V abc transporter atp-binding protein
MPDNDLLC_01416 3.9e-82 K WHG domain
MPDNDLLC_01417 1.1e-59 ydhF S Aldo keto reductase
MPDNDLLC_01418 2.9e-39 ydhF S Aldo keto reductase
MPDNDLLC_01420 5.7e-109 XK27_02070 S nitroreductase
MPDNDLLC_01421 1.2e-138 1.13.11.2 S glyoxalase
MPDNDLLC_01422 5.6e-77 ywnA K Transcriptional regulator
MPDNDLLC_01423 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
MPDNDLLC_01424 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MPDNDLLC_01425 1.4e-110 drgA C Nitroreductase
MPDNDLLC_01426 3e-102 yoaK S Protein of unknown function (DUF1275)
MPDNDLLC_01427 1.2e-160 yvgN C reductase
MPDNDLLC_01428 2.7e-182 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MPDNDLLC_01429 2.8e-282 XK27_07020 S Belongs to the UPF0371 family
MPDNDLLC_01431 1.1e-35 BP1961 P nitric oxide dioxygenase activity
MPDNDLLC_01432 4.8e-55 K response regulator
MPDNDLLC_01433 2.7e-71 S Signal peptide protein, YSIRK family
MPDNDLLC_01435 3.2e-59
MPDNDLLC_01436 1.7e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPDNDLLC_01437 1.9e-35
MPDNDLLC_01438 4e-20
MPDNDLLC_01439 1.5e-24 IQ PFAM AMP-dependent synthetase and ligase
MPDNDLLC_01440 2.7e-26 IQ PFAM AMP-dependent synthetase and ligase
MPDNDLLC_01441 5.8e-109 MA20_06410 E LysE type translocator
MPDNDLLC_01442 5.6e-08
MPDNDLLC_01443 2.7e-09
MPDNDLLC_01444 0.0 M family 8
MPDNDLLC_01446 2.8e-164 hrtB V MacB-like periplasmic core domain
MPDNDLLC_01447 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
MPDNDLLC_01448 1.1e-151 V MatE
MPDNDLLC_01450 1.5e-109 C Fe-S oxidoreductases
MPDNDLLC_01451 1.2e-176 EGP Major Facilitator Superfamily
MPDNDLLC_01452 5.5e-258 I radical SAM domain protein
MPDNDLLC_01454 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MPDNDLLC_01455 1.4e-150 L Integrase core domain protein
MPDNDLLC_01456 1.8e-87 L transposase activity
MPDNDLLC_01458 3.9e-92
MPDNDLLC_01459 0.0 sbcC L ATPase involved in DNA repair
MPDNDLLC_01460 5.3e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MPDNDLLC_01461 0.0 lacL 3.2.1.23 G -beta-galactosidase
MPDNDLLC_01462 0.0 lacS G transporter
MPDNDLLC_01463 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MPDNDLLC_01464 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MPDNDLLC_01465 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MPDNDLLC_01466 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MPDNDLLC_01467 2.3e-184 galR K Transcriptional regulator
MPDNDLLC_01468 2.7e-08 L Integrase core domain protein
MPDNDLLC_01469 1.2e-25 L transposition
MPDNDLLC_01470 2.7e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
MPDNDLLC_01471 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
MPDNDLLC_01472 2.5e-101 V abc transporter atp-binding protein
MPDNDLLC_01473 4.3e-40 V abc transporter atp-binding protein
MPDNDLLC_01474 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
MPDNDLLC_01475 6.4e-62 L Transposase
MPDNDLLC_01476 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01477 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01478 1.1e-119 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01479 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MPDNDLLC_01480 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MPDNDLLC_01481 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MPDNDLLC_01482 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MPDNDLLC_01485 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPDNDLLC_01486 5.8e-175 vraS 2.7.13.3 T Histidine kinase
MPDNDLLC_01487 8.3e-120 yvqF KT membrane
MPDNDLLC_01488 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MPDNDLLC_01489 2e-132 stp 3.1.3.16 T phosphatase
MPDNDLLC_01490 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MPDNDLLC_01491 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MPDNDLLC_01492 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MPDNDLLC_01493 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
MPDNDLLC_01494 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MPDNDLLC_01495 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MPDNDLLC_01496 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
MPDNDLLC_01497 2.1e-148 supH S overlaps another CDS with the same product name
MPDNDLLC_01498 8.6e-63 yvoA_1 K Transcriptional
MPDNDLLC_01499 2.8e-120 skfE V abc transporter atp-binding protein
MPDNDLLC_01500 6.2e-132 V ATPase activity
MPDNDLLC_01501 1.2e-171 oppF P Belongs to the ABC transporter superfamily
MPDNDLLC_01502 1.4e-203 oppD P Belongs to the ABC transporter superfamily
MPDNDLLC_01503 3.1e-167 amiD P ABC transporter (Permease
MPDNDLLC_01504 1.1e-270 amiC P ABC transporter (Permease
MPDNDLLC_01505 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MPDNDLLC_01506 2.7e-157 L COG2801 Transposase and inactivated derivatives
MPDNDLLC_01507 8.1e-45 L Transposase
MPDNDLLC_01508 1.2e-24 oppF P Belongs to the ABC transporter superfamily
MPDNDLLC_01509 3.5e-24 oppF P Belongs to the ABC transporter superfamily
MPDNDLLC_01510 8.9e-40 tatD L Hydrolase, tatd
MPDNDLLC_01511 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
MPDNDLLC_01512 1e-110 L Integrase core domain protein
MPDNDLLC_01513 1.1e-23 L transposase activity
MPDNDLLC_01514 8.9e-18 L transposase activity
MPDNDLLC_01515 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MPDNDLLC_01516 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MPDNDLLC_01517 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MPDNDLLC_01518 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
MPDNDLLC_01519 1.5e-103 yjbK S Adenylate cyclase
MPDNDLLC_01520 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MPDNDLLC_01521 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
MPDNDLLC_01522 2e-58 XK27_04120 S Putative amino acid metabolism
MPDNDLLC_01523 1.1e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MPDNDLLC_01524 1.6e-131 puuD T peptidase C26
MPDNDLLC_01525 6.2e-120 radC E Belongs to the UPF0758 family
MPDNDLLC_01526 1.7e-268 M Psort location CytoplasmicMembrane, score
MPDNDLLC_01527 0.0 rgpF M Rhamnan synthesis protein F
MPDNDLLC_01528 4.5e-305 GT4 M transferase activity, transferring glycosyl groups
MPDNDLLC_01529 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MPDNDLLC_01530 2.1e-143 rgpC GM Transport permease protein
MPDNDLLC_01531 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
MPDNDLLC_01532 2.3e-228 rgpA GT4 M Domain of unknown function (DUF1972)
MPDNDLLC_01533 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
MPDNDLLC_01534 4.6e-42 S Uncharacterized conserved protein (DUF2304)
MPDNDLLC_01535 6.9e-130 arnC M group 2 family protein
MPDNDLLC_01536 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
MPDNDLLC_01537 9.3e-186 S Glycosyltransferase like family 2
MPDNDLLC_01538 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
MPDNDLLC_01539 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MPDNDLLC_01540 2.9e-235 S Predicted membrane protein (DUF2142)
MPDNDLLC_01541 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MPDNDLLC_01542 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
MPDNDLLC_01543 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MPDNDLLC_01544 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MPDNDLLC_01545 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MPDNDLLC_01546 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
MPDNDLLC_01547 1.6e-202 arcT 2.6.1.1 E Aminotransferase
MPDNDLLC_01548 9.4e-136 ET ABC transporter
MPDNDLLC_01549 2.8e-143 ET Belongs to the bacterial solute-binding protein 3 family
MPDNDLLC_01550 2.9e-84 mutT 3.6.1.55 F Nudix family
MPDNDLLC_01551 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MPDNDLLC_01553 3e-74 S CAAX amino terminal protease family protein
MPDNDLLC_01554 2.6e-32 S CAAX amino terminal protease family protein
MPDNDLLC_01555 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MPDNDLLC_01556 1.8e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
MPDNDLLC_01557 1.1e-16 XK27_00735
MPDNDLLC_01558 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MPDNDLLC_01560 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MPDNDLLC_01563 1.6e-64 paaI Q protein possibly involved in aromatic compounds catabolism
MPDNDLLC_01564 6.6e-30 ycaO O OsmC-like protein
MPDNDLLC_01566 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
MPDNDLLC_01568 8.2e-114 serB 3.1.3.3 E phosphoserine phosphatase
MPDNDLLC_01569 1.4e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MPDNDLLC_01570 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MPDNDLLC_01571 2.6e-109 3.1.3.18 S IA, variant 1
MPDNDLLC_01572 6.5e-117 lrgB M effector of murein hydrolase
MPDNDLLC_01573 7.7e-56 lrgA S Effector of murein hydrolase LrgA
MPDNDLLC_01575 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
MPDNDLLC_01576 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
MPDNDLLC_01577 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MPDNDLLC_01578 3.9e-104 wecD M Acetyltransferase GNAT family
MPDNDLLC_01579 1.8e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MPDNDLLC_01580 5.1e-96 GK ROK family
MPDNDLLC_01581 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
MPDNDLLC_01582 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
MPDNDLLC_01583 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
MPDNDLLC_01584 2.3e-206 potD P spermidine putrescine ABC transporter
MPDNDLLC_01585 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
MPDNDLLC_01586 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
MPDNDLLC_01587 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MPDNDLLC_01588 7.8e-171 murB 1.3.1.98 M cell wall formation
MPDNDLLC_01589 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MPDNDLLC_01590 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MPDNDLLC_01591 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MPDNDLLC_01592 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MPDNDLLC_01593 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
MPDNDLLC_01594 0.0 ydaO E amino acid
MPDNDLLC_01595 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MPDNDLLC_01596 4.1e-37 ylqC L Belongs to the UPF0109 family
MPDNDLLC_01597 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MPDNDLLC_01598 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
MPDNDLLC_01599 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
MPDNDLLC_01600 2.1e-74 S QueT transporter
MPDNDLLC_01601 1.9e-55 L Transposase
MPDNDLLC_01602 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MPDNDLLC_01603 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MPDNDLLC_01604 3.7e-85 ccl S cog cog4708
MPDNDLLC_01605 7.4e-164 rbn E Belongs to the UPF0761 family
MPDNDLLC_01606 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MPDNDLLC_01607 3.3e-231 ytoI K transcriptional regulator containing CBS domains
MPDNDLLC_01608 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
MPDNDLLC_01609 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MPDNDLLC_01610 0.0 comEC S Competence protein ComEC
MPDNDLLC_01611 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MPDNDLLC_01612 1.3e-142 plsC 2.3.1.51 I Acyltransferase
MPDNDLLC_01613 4.4e-73 nodB3 G polysaccharide deacetylase
MPDNDLLC_01614 1.5e-61 nodB3 G deacetylase
MPDNDLLC_01615 7.1e-141 yabB 2.1.1.223 L Methyltransferase
MPDNDLLC_01616 1e-41 yazA L endonuclease containing a URI domain
MPDNDLLC_01617 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MPDNDLLC_01618 2.3e-154 corA P CorA-like protein
MPDNDLLC_01619 1.9e-62 yjqA S Bacterial PH domain
MPDNDLLC_01620 7.8e-100 thiT S Thiamine transporter
MPDNDLLC_01621 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MPDNDLLC_01622 1.9e-201 yjbB G Permeases of the major facilitator superfamily
MPDNDLLC_01623 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MPDNDLLC_01624 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
MPDNDLLC_01625 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MPDNDLLC_01629 1.1e-155 cjaA ET ABC transporter substrate-binding protein
MPDNDLLC_01630 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
MPDNDLLC_01631 1.3e-114 P ABC transporter (Permease
MPDNDLLC_01632 1e-114 papP P ABC transporter (Permease
MPDNDLLC_01633 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MPDNDLLC_01634 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
MPDNDLLC_01635 0.0 copA 3.6.3.54 P P-type ATPase
MPDNDLLC_01636 2.7e-73 copY K Copper transport repressor, CopY TcrY family
MPDNDLLC_01637 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MPDNDLLC_01638 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MPDNDLLC_01639 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
MPDNDLLC_01640 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MPDNDLLC_01641 1e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MPDNDLLC_01642 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
MPDNDLLC_01643 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MPDNDLLC_01644 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
MPDNDLLC_01645 3.2e-56
MPDNDLLC_01646 0.0 ctpE P E1-E2 ATPase
MPDNDLLC_01647 3.9e-26
MPDNDLLC_01648 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MPDNDLLC_01649 9.7e-28 L transposase activity
MPDNDLLC_01650 2.7e-129 K transcriptional regulator, MerR family
MPDNDLLC_01651 1.6e-103 dnaQ 2.7.7.7 L DNA polymerase III
MPDNDLLC_01652 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
MPDNDLLC_01653 4.8e-63 XK27_02560 S cog cog2151
MPDNDLLC_01654 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MPDNDLLC_01655 7.7e-227 ytfP S Flavoprotein
MPDNDLLC_01657 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MPDNDLLC_01658 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
MPDNDLLC_01659 2.3e-182 ecsB U ABC transporter
MPDNDLLC_01660 2.3e-133 ecsA V abc transporter atp-binding protein
MPDNDLLC_01661 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MPDNDLLC_01662 2.3e-10
MPDNDLLC_01663 2.7e-57 S CD20-like family
MPDNDLLC_01664 4.7e-106
MPDNDLLC_01665 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
MPDNDLLC_01666 6.9e-206 ylbM S Belongs to the UPF0348 family
MPDNDLLC_01667 2e-140 yqeM Q Methyltransferase domain protein
MPDNDLLC_01668 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MPDNDLLC_01669 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MPDNDLLC_01670 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MPDNDLLC_01671 3.5e-49 yhbY J RNA-binding protein
MPDNDLLC_01672 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MPDNDLLC_01673 1.8e-98 yqeG S hydrolase of the HAD superfamily
MPDNDLLC_01674 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MPDNDLLC_01675 6.2e-51
MPDNDLLC_01676 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MPDNDLLC_01677 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MPDNDLLC_01678 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MPDNDLLC_01679 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MPDNDLLC_01680 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MPDNDLLC_01681 1.9e-97 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MPDNDLLC_01682 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MPDNDLLC_01683 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
MPDNDLLC_01684 6.8e-101 pncA Q isochorismatase
MPDNDLLC_01685 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MPDNDLLC_01686 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
MPDNDLLC_01687 2.4e-75 XK27_03180 T universal stress protein
MPDNDLLC_01690 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MPDNDLLC_01691 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
MPDNDLLC_01692 1.2e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
MPDNDLLC_01693 0.0 yjcE P NhaP-type Na H and K H antiporters
MPDNDLLC_01695 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
MPDNDLLC_01696 1.3e-184 yhcC S radical SAM protein
MPDNDLLC_01697 2.2e-196 ylbL T Belongs to the peptidase S16 family
MPDNDLLC_01698 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MPDNDLLC_01699 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
MPDNDLLC_01700 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MPDNDLLC_01701 1.9e-09 S Protein of unknown function (DUF4059)
MPDNDLLC_01702 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
MPDNDLLC_01703 1e-162 yxeN P ABC transporter (Permease
MPDNDLLC_01704 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MPDNDLLC_01706 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPDNDLLC_01707 0.0 pflB 2.3.1.54 C formate acetyltransferase'
MPDNDLLC_01708 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
MPDNDLLC_01709 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPDNDLLC_01710 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
MPDNDLLC_01711 2.9e-87 D nuclear chromosome segregation
MPDNDLLC_01712 1.5e-127 ybbM S transport system, permease component
MPDNDLLC_01713 8e-117 ybbL S abc transporter atp-binding protein
MPDNDLLC_01714 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
MPDNDLLC_01715 4.6e-140 cppA E CppA N-terminal
MPDNDLLC_01716 5e-44 V CAAX protease self-immunity
MPDNDLLC_01717 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MPDNDLLC_01718 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MPDNDLLC_01721 3e-47 spiA K sequence-specific DNA binding
MPDNDLLC_01722 2.9e-28 blpT
MPDNDLLC_01723 6.7e-98 blpT
MPDNDLLC_01730 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
MPDNDLLC_01734 7.4e-135 agrA KT phosphorelay signal transduction system
MPDNDLLC_01735 4.2e-237 blpH 2.7.13.3 T protein histidine kinase activity
MPDNDLLC_01737 7.3e-237 mesE M Transport protein ComB
MPDNDLLC_01738 5.8e-166 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MPDNDLLC_01739 3e-224 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MPDNDLLC_01740 0.0 mdlB V abc transporter atp-binding protein
MPDNDLLC_01741 2.7e-302 mdlA V abc transporter atp-binding protein
MPDNDLLC_01743 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
MPDNDLLC_01744 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MPDNDLLC_01745 3.6e-70 yutD J protein conserved in bacteria
MPDNDLLC_01746 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MPDNDLLC_01748 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MPDNDLLC_01749 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MPDNDLLC_01750 0.0 ftsI 3.4.16.4 M penicillin-binding protein
MPDNDLLC_01751 4.3e-47 ftsL D cell division protein FtsL
MPDNDLLC_01752 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MPDNDLLC_01753 1.6e-65
MPDNDLLC_01754 7.4e-27
MPDNDLLC_01755 2.6e-30
MPDNDLLC_01758 8.7e-33 yhaI J Protein of unknown function (DUF805)
MPDNDLLC_01759 2e-22 D nuclear chromosome segregation
MPDNDLLC_01760 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MPDNDLLC_01761 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MPDNDLLC_01762 2.2e-285 XK27_00765
MPDNDLLC_01763 8.1e-134 ecsA_2 V abc transporter atp-binding protein
MPDNDLLC_01764 5.2e-125 S Protein of unknown function (DUF554)
MPDNDLLC_01765 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MPDNDLLC_01766 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MPDNDLLC_01767 2.6e-121 liaI S membrane
MPDNDLLC_01768 5.2e-75 XK27_02470 K LytTr DNA-binding domain
MPDNDLLC_01769 7e-70 KT response to antibiotic
MPDNDLLC_01770 4.5e-17 KT response to antibiotic
MPDNDLLC_01771 5.9e-54 yebC M Membrane
MPDNDLLC_01772 2.9e-18 yebC M Membrane
MPDNDLLC_01773 3.1e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
MPDNDLLC_01774 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MPDNDLLC_01775 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MPDNDLLC_01776 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MPDNDLLC_01777 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MPDNDLLC_01778 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MPDNDLLC_01779 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MPDNDLLC_01780 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MPDNDLLC_01782 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
MPDNDLLC_01783 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
MPDNDLLC_01784 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
MPDNDLLC_01785 4.1e-291 scrB 3.2.1.26 GH32 G invertase
MPDNDLLC_01786 7.5e-180 scrR K Transcriptional
MPDNDLLC_01787 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MPDNDLLC_01788 3.4e-62 yqhY S protein conserved in bacteria
MPDNDLLC_01789 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MPDNDLLC_01790 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
MPDNDLLC_01791 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
MPDNDLLC_01793 8e-44 V 'abc transporter, ATP-binding protein
MPDNDLLC_01794 1e-58 V 'abc transporter, ATP-binding protein
MPDNDLLC_01797 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MPDNDLLC_01798 2e-169 corA P COG0598 Mg2 and Co2 transporters
MPDNDLLC_01799 3.1e-124 XK27_01040 S Pfam PF06570
MPDNDLLC_01801 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MPDNDLLC_01802 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MPDNDLLC_01803 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
MPDNDLLC_01804 9.5e-42 XK27_05745
MPDNDLLC_01805 2.5e-230 mutY L A G-specific adenine glycosylase
MPDNDLLC_01810 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MPDNDLLC_01811 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MPDNDLLC_01812 1e-93 cvpA S toxin biosynthetic process
MPDNDLLC_01813 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MPDNDLLC_01814 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MPDNDLLC_01815 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MPDNDLLC_01816 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MPDNDLLC_01817 2e-47 azlD E branched-chain amino acid
MPDNDLLC_01818 1.8e-114 azlC E AzlC protein
MPDNDLLC_01819 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MPDNDLLC_01820 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MPDNDLLC_01821 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
MPDNDLLC_01822 2.5e-33 ykzG S Belongs to the UPF0356 family
MPDNDLLC_01823 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MPDNDLLC_01824 2.7e-40 pscB M CHAP domain protein
MPDNDLLC_01825 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
MPDNDLLC_01826 8.5e-63 glnR K Transcriptional regulator
MPDNDLLC_01827 1.3e-87 S Fusaric acid resistance protein-like
MPDNDLLC_01828 1.1e-12
MPDNDLLC_01829 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MPDNDLLC_01830 3.2e-42 L Transposase
MPDNDLLC_01831 1.9e-46 L transposase activity
MPDNDLLC_01832 7.4e-23 L Transposase
MPDNDLLC_01833 1.8e-56 L transposition
MPDNDLLC_01834 9.1e-83 L Integrase core domain protein
MPDNDLLC_01835 1e-102 L Transposase
MPDNDLLC_01836 4.1e-110 L Transposase
MPDNDLLC_01837 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MPDNDLLC_01838 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MPDNDLLC_01839 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MPDNDLLC_01840 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MPDNDLLC_01841 1.1e-142 purR 2.4.2.7 F operon repressor
MPDNDLLC_01842 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
MPDNDLLC_01843 6.9e-173 rmuC S RmuC domain protein
MPDNDLLC_01844 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
MPDNDLLC_01845 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MPDNDLLC_01846 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MPDNDLLC_01848 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MPDNDLLC_01849 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MPDNDLLC_01850 4.1e-144 tatD L Hydrolase, tatd
MPDNDLLC_01851 1.9e-74 yccU S CoA-binding protein
MPDNDLLC_01852 4.8e-51 trxA O Belongs to the thioredoxin family
MPDNDLLC_01853 1.9e-141 S Macro domain protein
MPDNDLLC_01854 2e-09 L thioesterase
MPDNDLLC_01855 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
MPDNDLLC_01858 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MPDNDLLC_01859 1e-33 L Transposase
MPDNDLLC_01860 1e-13 rpmH J Ribosomal protein L34
MPDNDLLC_01861 1e-185 jag S RNA-binding protein
MPDNDLLC_01862 8.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MPDNDLLC_01863 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MPDNDLLC_01864 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
MPDNDLLC_01865 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MPDNDLLC_01866 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MPDNDLLC_01867 6.7e-81 amiA E transmembrane transport
MPDNDLLC_01868 2e-41 amiA E transmembrane transport
MPDNDLLC_01869 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
MPDNDLLC_01870 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
MPDNDLLC_01871 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MPDNDLLC_01872 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MPDNDLLC_01873 9.2e-51 S Protein of unknown function (DUF3397)
MPDNDLLC_01874 6.6e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MPDNDLLC_01875 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
MPDNDLLC_01876 1.8e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
MPDNDLLC_01877 1.7e-221 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MPDNDLLC_01878 5.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MPDNDLLC_01879 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
MPDNDLLC_01880 9.5e-77 XK27_09620 S reductase
MPDNDLLC_01881 9e-62 XK27_09615 C reductase
MPDNDLLC_01882 2.3e-141 XK27_09615 C reductase
MPDNDLLC_01883 3.2e-62 fnt P Formate nitrite transporter
MPDNDLLC_01884 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
MPDNDLLC_01885 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MPDNDLLC_01886 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MPDNDLLC_01887 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MPDNDLLC_01888 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MPDNDLLC_01889 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MPDNDLLC_01890 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MPDNDLLC_01891 2.7e-48 S glycolate biosynthetic process
MPDNDLLC_01892 1.3e-63 S phosphatase activity
MPDNDLLC_01893 7e-158 rrmA 2.1.1.187 Q methyltransferase
MPDNDLLC_01896 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MPDNDLLC_01897 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MPDNDLLC_01898 6.4e-37 yeeD O sulfur carrier activity
MPDNDLLC_01899 2e-191 yeeE S Sulphur transport
MPDNDLLC_01900 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MPDNDLLC_01901 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MPDNDLLC_01902 4.1e-09 S Domain of unknown function (DUF4651)
MPDNDLLC_01903 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MPDNDLLC_01904 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MPDNDLLC_01905 1.8e-111 S CAAX amino terminal protease family protein
MPDNDLLC_01907 5e-67 V CAAX protease self-immunity
MPDNDLLC_01908 1.4e-33 V CAAX protease self-immunity
MPDNDLLC_01910 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MPDNDLLC_01911 5.9e-177 ytxK 2.1.1.72 L DNA methylase
MPDNDLLC_01912 2e-12 comGF U Putative Competence protein ComGF
MPDNDLLC_01913 1.5e-71 comGF U Competence protein ComGF
MPDNDLLC_01914 1.4e-15 NU Type II secretory pathway pseudopilin
MPDNDLLC_01915 1.8e-57 cglD NU Competence protein
MPDNDLLC_01916 8.5e-43 comGC U Required for transformation and DNA binding
MPDNDLLC_01917 1.1e-156 cglB U protein transport across the cell outer membrane
MPDNDLLC_01918 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MPDNDLLC_01919 2.9e-68 S cog cog4699
MPDNDLLC_01920 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MPDNDLLC_01921 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MPDNDLLC_01922 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MPDNDLLC_01923 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MPDNDLLC_01924 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MPDNDLLC_01925 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
MPDNDLLC_01926 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
MPDNDLLC_01927 1e-273 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MPDNDLLC_01928 6.2e-45 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MPDNDLLC_01929 1.1e-300 yloV S kinase related to dihydroxyacetone kinase
MPDNDLLC_01930 1.8e-57 asp S cog cog1302
MPDNDLLC_01931 3.2e-226 norN V Mate efflux family protein
MPDNDLLC_01932 1.9e-278 thrC 4.2.3.1 E Threonine synthase
MPDNDLLC_01933 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MPDNDLLC_01934 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
MPDNDLLC_01935 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MPDNDLLC_01936 1.4e-134 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MPDNDLLC_01937 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
MPDNDLLC_01938 0.0 pepO 3.4.24.71 O Peptidase family M13
MPDNDLLC_01939 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MPDNDLLC_01940 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MPDNDLLC_01941 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MPDNDLLC_01942 1.4e-54 treB 2.7.1.201 G PTS System
MPDNDLLC_01943 5.8e-21 treR K DNA-binding transcription factor activity
MPDNDLLC_01944 1.2e-85 treR K trehalose operon
MPDNDLLC_01945 3.3e-95 ywlG S Belongs to the UPF0340 family
MPDNDLLC_01948 3.3e-09 L PFAM Integrase, catalytic core
MPDNDLLC_01949 8.7e-73 L PFAM Integrase, catalytic core
MPDNDLLC_01950 1.5e-228 L Transposase
MPDNDLLC_01951 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MPDNDLLC_01952 3.1e-87 L Phage integrase family
MPDNDLLC_01953 5.7e-46 S Domain of unknown function (DUF4298)
MPDNDLLC_01954 4.5e-61 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
MPDNDLLC_01955 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MPDNDLLC_01956 1.8e-90 3.1.21.3 V Type I restriction modification DNA specificity domain
MPDNDLLC_01957 3.6e-304 hsdM 2.1.1.72 V HsdM N-terminal domain
MPDNDLLC_01958 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MPDNDLLC_01959 2.4e-26
MPDNDLLC_01960 1e-223 L Transposase
MPDNDLLC_01961 1.2e-137 L DNA integration
MPDNDLLC_01962 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
MPDNDLLC_01964 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
MPDNDLLC_01965 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
MPDNDLLC_01966 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
MPDNDLLC_01967 3.3e-09 L PFAM Integrase, catalytic core
MPDNDLLC_01968 4.2e-72 L PFAM Integrase, catalytic core
MPDNDLLC_01969 3.3e-62 rplQ J ribosomal protein l17
MPDNDLLC_01970 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MPDNDLLC_01971 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MPDNDLLC_01972 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MPDNDLLC_01973 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MPDNDLLC_01974 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MPDNDLLC_01975 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MPDNDLLC_01976 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MPDNDLLC_01977 4.4e-58 rplO J binds to the 23S rRNA
MPDNDLLC_01978 2.5e-23 rpmD J ribosomal protein l30
MPDNDLLC_01979 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MPDNDLLC_01980 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MPDNDLLC_01981 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MPDNDLLC_01982 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MPDNDLLC_01983 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MPDNDLLC_01984 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MPDNDLLC_01985 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MPDNDLLC_01986 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MPDNDLLC_01987 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MPDNDLLC_01988 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MPDNDLLC_01989 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MPDNDLLC_01990 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MPDNDLLC_01991 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MPDNDLLC_01992 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MPDNDLLC_01993 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MPDNDLLC_01994 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MPDNDLLC_01995 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
MPDNDLLC_01996 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MPDNDLLC_01997 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MPDNDLLC_01998 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MPDNDLLC_01999 0.0 XK27_09800 I Acyltransferase
MPDNDLLC_02000 1.7e-35 XK27_09805 S MORN repeat protein
MPDNDLLC_02001 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MPDNDLLC_02002 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MPDNDLLC_02003 8.8e-83 adk 2.7.4.3 F topology modulation protein
MPDNDLLC_02004 3.1e-172 yxaM EGP Major facilitator Superfamily
MPDNDLLC_02005 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
MPDNDLLC_02006 4.8e-54 L Transposase
MPDNDLLC_02007 2.8e-148 L Transposase
MPDNDLLC_02009 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MPDNDLLC_02010 0.0 KLT serine threonine protein kinase
MPDNDLLC_02011 2.1e-280 V ABC transporter
MPDNDLLC_02012 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MPDNDLLC_02013 5.4e-127 Z012_04635 K sequence-specific DNA binding
MPDNDLLC_02015 1.1e-15 C Radical SAM
MPDNDLLC_02016 3.4e-188 C Radical SAM
MPDNDLLC_02017 3.9e-287 V ABC transporter transmembrane region
MPDNDLLC_02018 3.2e-89 K sequence-specific DNA binding
MPDNDLLC_02019 1.3e-36 L Replication initiation factor
MPDNDLLC_02020 1.4e-107 L Replication initiation factor
MPDNDLLC_02021 1.9e-18 S Domain of unknown function (DUF3173)
MPDNDLLC_02022 3.5e-216 int L Belongs to the 'phage' integrase family
MPDNDLLC_02024 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
MPDNDLLC_02025 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MPDNDLLC_02026 2.8e-44 yrzL S Belongs to the UPF0297 family
MPDNDLLC_02027 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MPDNDLLC_02028 4.2e-44 yrzB S Belongs to the UPF0473 family
MPDNDLLC_02029 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
MPDNDLLC_02030 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MPDNDLLC_02031 7.5e-14
MPDNDLLC_02032 2.6e-91 XK27_10930 K acetyltransferase
MPDNDLLC_02033 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MPDNDLLC_02034 1.8e-147 yaaA S Belongs to the UPF0246 family
MPDNDLLC_02035 9.9e-169 XK27_01785 S cog cog1284
MPDNDLLC_02036 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MPDNDLLC_02038 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
MPDNDLLC_02039 5.7e-52 metE 2.1.1.14 E Methionine synthase
MPDNDLLC_02040 7.6e-64 metE 2.1.1.14 E Methionine synthase
MPDNDLLC_02041 1.4e-36 metE 2.1.1.14 E Methionine synthase
MPDNDLLC_02042 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MPDNDLLC_02043 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MPDNDLLC_02046 2.6e-49 yegS 2.7.1.107 I lipid kinase activity
MPDNDLLC_02047 6.1e-95 S Hydrophobic domain protein
MPDNDLLC_02049 3.7e-27 S Membrane
MPDNDLLC_02050 3.1e-101
MPDNDLLC_02051 1.8e-23 S Small integral membrane protein
MPDNDLLC_02052 1.1e-71 M Protein conserved in bacteria
MPDNDLLC_02053 4.9e-12 K CsbD-like
MPDNDLLC_02054 3.5e-97 nudL L hydrolase
MPDNDLLC_02055 3.4e-13 nudL L hydrolase
MPDNDLLC_02056 4e-19 K negative regulation of transcription, DNA-templated
MPDNDLLC_02057 1.7e-23 K negative regulation of transcription, DNA-templated
MPDNDLLC_02059 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
MPDNDLLC_02060 1.8e-88 S Putative adhesin
MPDNDLLC_02061 3.9e-161 XK27_06930 V domain protein
MPDNDLLC_02062 6.4e-96 XK27_06935 K transcriptional regulator
MPDNDLLC_02063 4.8e-55 ypaA M Membrane
MPDNDLLC_02064 2.7e-08
MPDNDLLC_02065 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MPDNDLLC_02066 8.2e-48 veg S Biofilm formation stimulator VEG
MPDNDLLC_02067 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MPDNDLLC_02068 3.9e-70 rplI J binds to the 23S rRNA
MPDNDLLC_02069 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MPDNDLLC_02070 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MPDNDLLC_02071 1.5e-77 F NUDIX domain
MPDNDLLC_02072 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MPDNDLLC_02073 0.0 S Bacterial membrane protein, YfhO
MPDNDLLC_02074 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
MPDNDLLC_02075 3.1e-93 lytE M LysM domain protein
MPDNDLLC_02076 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MPDNDLLC_02077 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MPDNDLLC_02078 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MPDNDLLC_02079 6.9e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MPDNDLLC_02080 3.7e-138 ymfM S sequence-specific DNA binding
MPDNDLLC_02081 1.4e-242 ymfH S Peptidase M16
MPDNDLLC_02082 1.4e-234 ymfF S Peptidase M16
MPDNDLLC_02083 3.1e-44 yaaA S S4 domain protein YaaA
MPDNDLLC_02084 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MPDNDLLC_02085 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MPDNDLLC_02086 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MPDNDLLC_02087 4.2e-153 yvjA S membrane
MPDNDLLC_02088 3.3e-305 ybiT S abc transporter atp-binding protein
MPDNDLLC_02089 0.0 XK27_10405 S Bacterial membrane protein YfhO
MPDNDLLC_02093 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
MPDNDLLC_02094 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MPDNDLLC_02095 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
MPDNDLLC_02096 8.5e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)