ORF_ID e_value Gene_name EC_number CAZy COGs Description
KPIMHEKK_00001 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
KPIMHEKK_00002 2.8e-77 P Cobalt transport protein
KPIMHEKK_00003 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
KPIMHEKK_00004 6.5e-91 G Peptidase_C39 like family
KPIMHEKK_00005 2.8e-162 M NlpC/P60 family
KPIMHEKK_00006 8.4e-25 G Peptidase_C39 like family
KPIMHEKK_00007 1.7e-152 mdtG EGP Major facilitator Superfamily
KPIMHEKK_00008 1.3e-174
KPIMHEKK_00009 2.8e-47 lysM M LysM domain
KPIMHEKK_00010 0.0 pepN 3.4.11.2 E aminopeptidase
KPIMHEKK_00011 1.3e-250 dtpT U amino acid peptide transporter
KPIMHEKK_00012 1.2e-18 S Sugar efflux transporter for intercellular exchange
KPIMHEKK_00013 6.6e-70 XK27_02470 K LytTr DNA-binding domain
KPIMHEKK_00014 2.1e-92 liaI S membrane
KPIMHEKK_00015 4e-16
KPIMHEKK_00016 3.9e-186 S Putative peptidoglycan binding domain
KPIMHEKK_00017 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
KPIMHEKK_00018 9e-121
KPIMHEKK_00024 1.7e-29 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KPIMHEKK_00025 8.8e-84 S N-acetylmuramoyl-L-alanine amidase activity
KPIMHEKK_00027 1.8e-10
KPIMHEKK_00028 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KPIMHEKK_00029 2.3e-23 S Protein of unknown function (DUF2929)
KPIMHEKK_00030 0.0 dnaE 2.7.7.7 L DNA polymerase
KPIMHEKK_00031 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KPIMHEKK_00032 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KPIMHEKK_00033 1e-167 cvfB S S1 domain
KPIMHEKK_00034 2.9e-165 xerD D recombinase XerD
KPIMHEKK_00035 8.1e-54 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPIMHEKK_00036 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPIMHEKK_00037 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPIMHEKK_00038 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPIMHEKK_00039 2.2e-112 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPIMHEKK_00040 2.7e-18 M Lysin motif
KPIMHEKK_00041 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KPIMHEKK_00042 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
KPIMHEKK_00043 4.3e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KPIMHEKK_00044 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KPIMHEKK_00045 3.9e-229 S Tetratricopeptide repeat protein
KPIMHEKK_00046 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPIMHEKK_00047 1.1e-56 S Protein of unknown function (DUF3290)
KPIMHEKK_00048 3e-116 yviA S Protein of unknown function (DUF421)
KPIMHEKK_00049 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KPIMHEKK_00050 8e-182 dnaQ 2.7.7.7 L EXOIII
KPIMHEKK_00051 1.9e-158 endA F DNA RNA non-specific endonuclease
KPIMHEKK_00052 1.3e-281 pipD E Dipeptidase
KPIMHEKK_00053 1.9e-203 malK P ATPases associated with a variety of cellular activities
KPIMHEKK_00054 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
KPIMHEKK_00055 1.8e-145 gtsC P Binding-protein-dependent transport system inner membrane component
KPIMHEKK_00056 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
KPIMHEKK_00057 6.7e-240 G Bacterial extracellular solute-binding protein
KPIMHEKK_00058 1.8e-154 corA P CorA-like Mg2+ transporter protein
KPIMHEKK_00059 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
KPIMHEKK_00060 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
KPIMHEKK_00061 0.0 ydgH S MMPL family
KPIMHEKK_00063 7.8e-26 K Acetyltransferase (GNAT) domain
KPIMHEKK_00064 1.8e-163
KPIMHEKK_00065 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KPIMHEKK_00066 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPIMHEKK_00067 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
KPIMHEKK_00068 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KPIMHEKK_00069 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPIMHEKK_00070 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KPIMHEKK_00071 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPIMHEKK_00072 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KPIMHEKK_00073 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KPIMHEKK_00074 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KPIMHEKK_00075 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPIMHEKK_00076 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KPIMHEKK_00077 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPIMHEKK_00078 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPIMHEKK_00079 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPIMHEKK_00080 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPIMHEKK_00081 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KPIMHEKK_00082 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPIMHEKK_00083 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KPIMHEKK_00084 2.3e-24 rpmD J Ribosomal protein L30
KPIMHEKK_00085 1.3e-70 rplO J Binds to the 23S rRNA
KPIMHEKK_00086 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KPIMHEKK_00087 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KPIMHEKK_00088 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KPIMHEKK_00089 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KPIMHEKK_00090 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPIMHEKK_00091 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPIMHEKK_00092 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPIMHEKK_00093 1.4e-60 rplQ J Ribosomal protein L17
KPIMHEKK_00094 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPIMHEKK_00095 7.8e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPIMHEKK_00096 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPIMHEKK_00097 4.8e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KPIMHEKK_00098 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPIMHEKK_00099 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
KPIMHEKK_00100 8.9e-133 L Phage integrase family
KPIMHEKK_00101 4e-145 yfeO P Voltage gated chloride channel
KPIMHEKK_00102 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
KPIMHEKK_00103 2.8e-52
KPIMHEKK_00104 3.8e-42
KPIMHEKK_00105 7e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPIMHEKK_00106 1.3e-298 ybeC E amino acid
KPIMHEKK_00107 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
KPIMHEKK_00108 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
KPIMHEKK_00109 2.5e-39 rpmE2 J Ribosomal protein L31
KPIMHEKK_00110 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KPIMHEKK_00111 4.8e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KPIMHEKK_00112 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KPIMHEKK_00113 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPIMHEKK_00114 9.9e-129 S (CBS) domain
KPIMHEKK_00115 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KPIMHEKK_00116 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KPIMHEKK_00117 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPIMHEKK_00118 1.6e-33 yabO J S4 domain protein
KPIMHEKK_00119 6.8e-60 divIC D Septum formation initiator
KPIMHEKK_00120 6.3e-63 yabR J S1 RNA binding domain
KPIMHEKK_00121 3.4e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KPIMHEKK_00122 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPIMHEKK_00123 3.3e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPIMHEKK_00124 2.8e-193 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPIMHEKK_00125 7.8e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KPIMHEKK_00126 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KPIMHEKK_00127 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPIMHEKK_00128 1.2e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPIMHEKK_00129 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KPIMHEKK_00130 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KPIMHEKK_00131 1.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPIMHEKK_00132 4.2e-182 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KPIMHEKK_00133 2.6e-35 yaaA S S4 domain protein YaaA
KPIMHEKK_00134 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPIMHEKK_00135 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPIMHEKK_00136 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPIMHEKK_00137 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
KPIMHEKK_00138 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KPIMHEKK_00139 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KPIMHEKK_00140 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
KPIMHEKK_00141 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
KPIMHEKK_00142 3.5e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPIMHEKK_00143 4.7e-211 yttB EGP Major facilitator Superfamily
KPIMHEKK_00144 1.5e-230 XK27_04775 S PAS domain
KPIMHEKK_00145 2.1e-103 S Iron-sulfur cluster assembly protein
KPIMHEKK_00146 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPIMHEKK_00147 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KPIMHEKK_00148 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
KPIMHEKK_00149 0.0 asnB 6.3.5.4 E Asparagine synthase
KPIMHEKK_00150 1.7e-273 S Calcineurin-like phosphoesterase
KPIMHEKK_00151 3.9e-84
KPIMHEKK_00152 1.6e-105 tag 3.2.2.20 L glycosylase
KPIMHEKK_00153 4.1e-172 L COG3385 FOG Transposase and inactivated derivatives
KPIMHEKK_00155 1.9e-117 cps1D M Domain of unknown function (DUF4422)
KPIMHEKK_00156 6.7e-110 rfbP M Bacterial sugar transferase
KPIMHEKK_00157 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
KPIMHEKK_00158 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KPIMHEKK_00159 6.5e-146 epsB M biosynthesis protein
KPIMHEKK_00160 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPIMHEKK_00162 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
KPIMHEKK_00163 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KPIMHEKK_00164 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KPIMHEKK_00165 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPIMHEKK_00166 1.3e-148
KPIMHEKK_00167 6.4e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPIMHEKK_00168 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KPIMHEKK_00169 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
KPIMHEKK_00170 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
KPIMHEKK_00171 0.0 comEC S Competence protein ComEC
KPIMHEKK_00172 3.1e-79 comEA L Competence protein ComEA
KPIMHEKK_00173 2.4e-187 ylbL T Belongs to the peptidase S16 family
KPIMHEKK_00174 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPIMHEKK_00175 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KPIMHEKK_00176 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KPIMHEKK_00177 5.9e-211 ftsW D Belongs to the SEDS family
KPIMHEKK_00178 0.0 typA T GTP-binding protein TypA
KPIMHEKK_00179 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPIMHEKK_00180 3.5e-32 ykzG S Belongs to the UPF0356 family
KPIMHEKK_00181 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPIMHEKK_00182 1.9e-98 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KPIMHEKK_00184 1.2e-60 L Putative transposase DNA-binding domain
KPIMHEKK_00185 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KPIMHEKK_00186 9.3e-30 K Helix-turn-helix
KPIMHEKK_00187 7.7e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KPIMHEKK_00188 1.5e-223 pbuX F xanthine permease
KPIMHEKK_00189 3.7e-156 msmR K AraC-like ligand binding domain
KPIMHEKK_00190 1.4e-283 pipD E Dipeptidase
KPIMHEKK_00191 1e-77 K acetyltransferase
KPIMHEKK_00192 4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPIMHEKK_00193 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KPIMHEKK_00194 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KPIMHEKK_00195 6.9e-69 S Domain of unknown function (DUF1934)
KPIMHEKK_00196 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
KPIMHEKK_00197 5.6e-43
KPIMHEKK_00198 4.2e-172 2.7.1.2 GK ROK family
KPIMHEKK_00199 0.0 fhaB M Rib/alpha-like repeat
KPIMHEKK_00200 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
KPIMHEKK_00201 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KPIMHEKK_00202 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KPIMHEKK_00203 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KPIMHEKK_00204 6.8e-209 msmX P Belongs to the ABC transporter superfamily
KPIMHEKK_00205 1.3e-213 malE G Bacterial extracellular solute-binding protein
KPIMHEKK_00206 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
KPIMHEKK_00207 3.3e-147 malG P ABC transporter permease
KPIMHEKK_00208 4.3e-67 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_00211 4.8e-28
KPIMHEKK_00212 1.9e-75 M LysM domain
KPIMHEKK_00213 1.3e-42
KPIMHEKK_00215 4.9e-35
KPIMHEKK_00216 4.5e-76 yniG EGP Major facilitator Superfamily
KPIMHEKK_00217 5.4e-237 L transposase, IS605 OrfB family
KPIMHEKK_00218 1.4e-109 yniG EGP Major facilitator Superfamily
KPIMHEKK_00219 2.4e-128 S cog cog1373
KPIMHEKK_00220 5.9e-45
KPIMHEKK_00221 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KPIMHEKK_00223 2.1e-45 S PFAM Archaeal ATPase
KPIMHEKK_00224 7.3e-74
KPIMHEKK_00225 0.0 kup P Transport of potassium into the cell
KPIMHEKK_00226 1.4e-16
KPIMHEKK_00228 1.8e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KPIMHEKK_00229 1.1e-135 V ABC transporter transmembrane region
KPIMHEKK_00230 5.2e-170 degV S DegV family
KPIMHEKK_00231 3.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
KPIMHEKK_00232 9.2e-262 emrY EGP Major facilitator Superfamily
KPIMHEKK_00233 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPIMHEKK_00234 7.6e-239 pyrP F Permease
KPIMHEKK_00235 1.9e-22 K Putative DNA-binding domain
KPIMHEKK_00236 1.4e-15 S cog cog1373
KPIMHEKK_00237 1.4e-156 hipB K Helix-turn-helix
KPIMHEKK_00238 6e-151 I alpha/beta hydrolase fold
KPIMHEKK_00239 1.4e-110 yjbF S SNARE associated Golgi protein
KPIMHEKK_00240 7.5e-100 J Acetyltransferase (GNAT) domain
KPIMHEKK_00241 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPIMHEKK_00242 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
KPIMHEKK_00243 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
KPIMHEKK_00244 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
KPIMHEKK_00245 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
KPIMHEKK_00252 2.3e-103 M hydrolase, family 25
KPIMHEKK_00253 1.8e-38 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KPIMHEKK_00261 3.8e-06 S Domain of unknown function (DUF2479)
KPIMHEKK_00263 0.0 S Phage minor structural protein
KPIMHEKK_00264 3.3e-109 S phage tail
KPIMHEKK_00265 0.0 xkdO D NLP P60 protein
KPIMHEKK_00266 1.6e-85 S Bacteriophage Gp15 protein
KPIMHEKK_00267 8.7e-35
KPIMHEKK_00268 3.5e-83 N domain, Protein
KPIMHEKK_00269 3e-51 S Minor capsid protein from bacteriophage
KPIMHEKK_00270 4e-31 S Minor capsid protein
KPIMHEKK_00271 1.6e-39 S Minor capsid protein
KPIMHEKK_00272 2.4e-44
KPIMHEKK_00273 4.6e-154 gpG
KPIMHEKK_00274 1e-36 S Phage minor structural protein GP20
KPIMHEKK_00276 2.2e-165 S Phage minor capsid protein 2
KPIMHEKK_00277 4.9e-216 S Phage portal protein, SPP1 Gp6-like
KPIMHEKK_00278 3.2e-215 S Terminase RNAseH like domain
KPIMHEKK_00279 8.3e-85 L transposase activity
KPIMHEKK_00280 5.4e-111 K Belongs to the N(4) N(6)-methyltransferase family
KPIMHEKK_00281 2.2e-30
KPIMHEKK_00283 2.2e-101 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
KPIMHEKK_00284 4.3e-24 S ASCH domain
KPIMHEKK_00285 2.9e-07
KPIMHEKK_00293 4.7e-55 dnaC L IstB-like ATP binding protein
KPIMHEKK_00294 1.7e-34 S Conserved phage C-terminus (Phg_2220_C)
KPIMHEKK_00296 5.3e-41
KPIMHEKK_00297 1.4e-76 K DNA-templated transcription, initiation
KPIMHEKK_00298 1.1e-25
KPIMHEKK_00299 2.1e-144 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KPIMHEKK_00301 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KPIMHEKK_00302 1.7e-100 S SLAP domain
KPIMHEKK_00303 4.3e-40 S Protein of unknown function (DUF2922)
KPIMHEKK_00304 5.5e-30
KPIMHEKK_00306 1.4e-37 S Putative adhesin
KPIMHEKK_00307 2.6e-151 V ABC transporter transmembrane region
KPIMHEKK_00308 4.6e-138
KPIMHEKK_00309 1.8e-31
KPIMHEKK_00312 2.4e-36
KPIMHEKK_00313 9.2e-57 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KPIMHEKK_00314 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KPIMHEKK_00315 0.0 copA 3.6.3.54 P P-type ATPase
KPIMHEKK_00316 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KPIMHEKK_00317 1.2e-105
KPIMHEKK_00318 7e-248 EGP Sugar (and other) transporter
KPIMHEKK_00319 1.2e-18
KPIMHEKK_00320 2.8e-210
KPIMHEKK_00321 3.5e-136 S SLAP domain
KPIMHEKK_00322 1.3e-117 S SLAP domain
KPIMHEKK_00323 1.1e-106 S Bacteriocin helveticin-J
KPIMHEKK_00324 1.2e-44
KPIMHEKK_00325 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_00326 3.6e-33 E Zn peptidase
KPIMHEKK_00327 2.5e-286 clcA P chloride
KPIMHEKK_00328 1.8e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KPIMHEKK_00329 5.2e-114
KPIMHEKK_00330 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KPIMHEKK_00331 5.3e-26
KPIMHEKK_00332 8.5e-41 ptsH G phosphocarrier protein HPR
KPIMHEKK_00333 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KPIMHEKK_00334 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KPIMHEKK_00335 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KPIMHEKK_00336 1.4e-158 coiA 3.6.4.12 S Competence protein
KPIMHEKK_00337 4.6e-114 yjbH Q Thioredoxin
KPIMHEKK_00338 6.8e-110 yjbK S CYTH
KPIMHEKK_00339 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
KPIMHEKK_00340 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPIMHEKK_00341 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPIMHEKK_00342 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KPIMHEKK_00343 4.2e-92 S SNARE associated Golgi protein
KPIMHEKK_00344 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KPIMHEKK_00345 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KPIMHEKK_00346 2.6e-214 yubA S AI-2E family transporter
KPIMHEKK_00347 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KPIMHEKK_00348 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
KPIMHEKK_00349 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KPIMHEKK_00350 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
KPIMHEKK_00351 1.9e-236 S Peptidase M16
KPIMHEKK_00352 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
KPIMHEKK_00353 5.2e-97 ymfM S Helix-turn-helix domain
KPIMHEKK_00354 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPIMHEKK_00355 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPIMHEKK_00356 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
KPIMHEKK_00357 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
KPIMHEKK_00358 5.1e-119 yvyE 3.4.13.9 S YigZ family
KPIMHEKK_00359 4.7e-246 comFA L Helicase C-terminal domain protein
KPIMHEKK_00360 9.4e-132 comFC S Competence protein
KPIMHEKK_00361 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPIMHEKK_00362 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KPIMHEKK_00363 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KPIMHEKK_00364 5.1e-17
KPIMHEKK_00365 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPIMHEKK_00366 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPIMHEKK_00367 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KPIMHEKK_00368 1.5e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KPIMHEKK_00369 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KPIMHEKK_00370 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KPIMHEKK_00371 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KPIMHEKK_00372 4.1e-90 S Short repeat of unknown function (DUF308)
KPIMHEKK_00373 6.2e-165 rapZ S Displays ATPase and GTPase activities
KPIMHEKK_00374 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KPIMHEKK_00375 2.1e-171 whiA K May be required for sporulation
KPIMHEKK_00376 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KPIMHEKK_00377 0.0 S SH3-like domain
KPIMHEKK_00378 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KPIMHEKK_00379 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
KPIMHEKK_00380 1e-30 S cog cog1373
KPIMHEKK_00381 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KPIMHEKK_00382 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KPIMHEKK_00383 6.7e-98 M ErfK YbiS YcfS YnhG
KPIMHEKK_00384 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KPIMHEKK_00385 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KPIMHEKK_00387 4.7e-46 pspC KT PspC domain
KPIMHEKK_00388 3.3e-237 L COG2963 Transposase and inactivated derivatives
KPIMHEKK_00391 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
KPIMHEKK_00394 1.2e-32 M Peptidase family M23
KPIMHEKK_00395 1.8e-159 trsE S COG0433 Predicted ATPase
KPIMHEKK_00396 2.4e-14
KPIMHEKK_00398 3.9e-32 I mechanosensitive ion channel activity
KPIMHEKK_00399 2.3e-86 U TraM recognition site of TraD and TraG
KPIMHEKK_00400 3.2e-19
KPIMHEKK_00402 3.2e-182 M Glycosyl hydrolases family 25
KPIMHEKK_00403 8e-27
KPIMHEKK_00404 7e-16
KPIMHEKK_00406 1.7e-16
KPIMHEKK_00408 1.2e-10
KPIMHEKK_00413 6.4e-70
KPIMHEKK_00414 3.4e-35
KPIMHEKK_00415 1.4e-09
KPIMHEKK_00416 1.4e-87 Z012_12235 S Baseplate J-like protein
KPIMHEKK_00417 5e-29
KPIMHEKK_00418 5.7e-171 M Glycosyl hydrolases family 25
KPIMHEKK_00421 1.3e-122 S haloacid dehalogenase-like hydrolase
KPIMHEKK_00422 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
KPIMHEKK_00423 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
KPIMHEKK_00424 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
KPIMHEKK_00425 8.5e-178 I Carboxylesterase family
KPIMHEKK_00427 1e-205 M Glycosyl hydrolases family 25
KPIMHEKK_00428 1.2e-155 cinI S Serine hydrolase (FSH1)
KPIMHEKK_00429 4.3e-298 S Predicted membrane protein (DUF2207)
KPIMHEKK_00430 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KPIMHEKK_00432 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
KPIMHEKK_00433 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPIMHEKK_00434 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KPIMHEKK_00435 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KPIMHEKK_00436 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KPIMHEKK_00437 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPIMHEKK_00438 3.4e-71 yqhY S Asp23 family, cell envelope-related function
KPIMHEKK_00439 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPIMHEKK_00440 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPIMHEKK_00441 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPIMHEKK_00442 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPIMHEKK_00443 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KPIMHEKK_00444 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KPIMHEKK_00445 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
KPIMHEKK_00446 1.1e-77 6.3.3.2 S ASCH
KPIMHEKK_00447 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KPIMHEKK_00448 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KPIMHEKK_00449 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPIMHEKK_00450 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPIMHEKK_00451 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPIMHEKK_00452 1.1e-138 stp 3.1.3.16 T phosphatase
KPIMHEKK_00453 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KPIMHEKK_00454 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KPIMHEKK_00455 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KPIMHEKK_00456 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
KPIMHEKK_00457 1.4e-30
KPIMHEKK_00458 9.9e-118 L Belongs to the 'phage' integrase family
KPIMHEKK_00460 2.2e-15 E Pfam:DUF955
KPIMHEKK_00462 4.7e-18 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_00463 4.4e-79 S Phage antirepressor protein KilAC domain
KPIMHEKK_00464 3.5e-46
KPIMHEKK_00470 1.6e-70 S AAA domain
KPIMHEKK_00472 1.4e-147 res L Helicase C-terminal domain protein
KPIMHEKK_00473 1.7e-30 S Protein of unknown function (DUF669)
KPIMHEKK_00474 2.7e-268 S Phage plasmid primase, P4
KPIMHEKK_00485 3.3e-37 S VRR_NUC
KPIMHEKK_00487 9.8e-12
KPIMHEKK_00488 3.1e-14 arpU S Phage transcriptional regulator, ArpU family
KPIMHEKK_00490 3.5e-49 L HNH nucleases
KPIMHEKK_00491 1.6e-55 L Phage terminase, small subunit
KPIMHEKK_00492 3.4e-18 N HicA toxin of bacterial toxin-antitoxin,
KPIMHEKK_00493 9e-47 S HicB_like antitoxin of bacterial toxin-antitoxin system
KPIMHEKK_00494 2.8e-210 S Phage Terminase
KPIMHEKK_00496 1.5e-134 S Phage portal protein
KPIMHEKK_00497 5.5e-87 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KPIMHEKK_00498 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
KPIMHEKK_00499 3.4e-79
KPIMHEKK_00500 1e-242 cpdA S Calcineurin-like phosphoesterase
KPIMHEKK_00501 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KPIMHEKK_00502 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KPIMHEKK_00503 1e-107 ypsA S Belongs to the UPF0398 family
KPIMHEKK_00504 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KPIMHEKK_00505 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KPIMHEKK_00506 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPIMHEKK_00507 1.3e-114 dnaD L DnaD domain protein
KPIMHEKK_00508 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KPIMHEKK_00509 2.4e-89 ypmB S Protein conserved in bacteria
KPIMHEKK_00510 3e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KPIMHEKK_00511 9.2e-14
KPIMHEKK_00512 2.1e-173 M Glycosyl hydrolases family 25
KPIMHEKK_00513 1.9e-28
KPIMHEKK_00514 4e-08
KPIMHEKK_00515 6.6e-56
KPIMHEKK_00516 2.7e-57
KPIMHEKK_00517 1.6e-11
KPIMHEKK_00518 8.1e-126 S PAS domain
KPIMHEKK_00519 0.0 V FtsX-like permease family
KPIMHEKK_00520 4.1e-133 cysA V ABC transporter, ATP-binding protein
KPIMHEKK_00521 3.4e-23
KPIMHEKK_00522 2.5e-288 pipD E Dipeptidase
KPIMHEKK_00523 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KPIMHEKK_00524 0.0 smc D Required for chromosome condensation and partitioning
KPIMHEKK_00525 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KPIMHEKK_00526 2.1e-308 oppA E ABC transporter substrate-binding protein
KPIMHEKK_00527 3.1e-240 oppA E ABC transporter substrate-binding protein
KPIMHEKK_00528 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
KPIMHEKK_00529 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
KPIMHEKK_00530 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
KPIMHEKK_00531 5.9e-09
KPIMHEKK_00532 4.4e-43
KPIMHEKK_00533 8.7e-66 2.7.1.191 G PTS system fructose IIA component
KPIMHEKK_00534 0.0 3.6.3.8 P P-type ATPase
KPIMHEKK_00535 4.9e-125
KPIMHEKK_00536 1.2e-241 S response to antibiotic
KPIMHEKK_00537 7.5e-231 pbuG S permease
KPIMHEKK_00538 2.5e-119 K helix_turn_helix, mercury resistance
KPIMHEKK_00539 3.3e-37
KPIMHEKK_00540 6e-112
KPIMHEKK_00542 1.7e-110 E Belongs to the SOS response-associated peptidase family
KPIMHEKK_00543 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPIMHEKK_00544 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
KPIMHEKK_00545 2e-103 S TPM domain
KPIMHEKK_00546 2.4e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KPIMHEKK_00547 2.5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KPIMHEKK_00548 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPIMHEKK_00549 1e-147 tatD L hydrolase, TatD family
KPIMHEKK_00550 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPIMHEKK_00551 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KPIMHEKK_00552 4.5e-39 veg S Biofilm formation stimulator VEG
KPIMHEKK_00553 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KPIMHEKK_00554 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPIMHEKK_00555 5.3e-80
KPIMHEKK_00556 1.2e-292 S SLAP domain
KPIMHEKK_00557 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPIMHEKK_00558 2.2e-142 S Belongs to the UPF0246 family
KPIMHEKK_00559 4.1e-141 aroD S Alpha/beta hydrolase family
KPIMHEKK_00560 3.5e-111 G phosphoglycerate mutase
KPIMHEKK_00561 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
KPIMHEKK_00562 3.3e-176 hrtB V ABC transporter permease
KPIMHEKK_00563 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KPIMHEKK_00564 1.3e-273 pipD E Dipeptidase
KPIMHEKK_00565 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KPIMHEKK_00566 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KPIMHEKK_00567 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KPIMHEKK_00568 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KPIMHEKK_00569 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KPIMHEKK_00570 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPIMHEKK_00571 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KPIMHEKK_00572 2.3e-56 G Xylose isomerase domain protein TIM barrel
KPIMHEKK_00573 8.4e-90 nanK GK ROK family
KPIMHEKK_00574 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KPIMHEKK_00575 3.7e-66 K Helix-turn-helix domain, rpiR family
KPIMHEKK_00576 7.1e-263 E ABC transporter, substratebinding protein
KPIMHEKK_00578 1.2e-128 S interspecies interaction between organisms
KPIMHEKK_00579 1.9e-11
KPIMHEKK_00582 1.9e-21
KPIMHEKK_00583 6e-148
KPIMHEKK_00584 6.7e-170
KPIMHEKK_00585 2e-263 glnA 6.3.1.2 E glutamine synthetase
KPIMHEKK_00586 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
KPIMHEKK_00587 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPIMHEKK_00588 1.5e-65 yqhL P Rhodanese-like protein
KPIMHEKK_00589 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
KPIMHEKK_00590 4e-119 gluP 3.4.21.105 S Rhomboid family
KPIMHEKK_00591 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPIMHEKK_00592 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KPIMHEKK_00593 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KPIMHEKK_00594 0.0 S membrane
KPIMHEKK_00595 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
KPIMHEKK_00596 1.3e-38 S RelB antitoxin
KPIMHEKK_00597 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KPIMHEKK_00598 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KPIMHEKK_00599 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
KPIMHEKK_00600 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPIMHEKK_00601 8.7e-159 isdE P Periplasmic binding protein
KPIMHEKK_00602 6.3e-123 M Iron Transport-associated domain
KPIMHEKK_00603 3e-09 isdH M Iron Transport-associated domain
KPIMHEKK_00604 2.2e-89
KPIMHEKK_00605 8.8e-29
KPIMHEKK_00608 4.9e-111 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_00609 2.5e-75 K Helix-turn-helix domain
KPIMHEKK_00610 1.5e-25 S CAAX protease self-immunity
KPIMHEKK_00611 1.4e-22 S CAAX protease self-immunity
KPIMHEKK_00612 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_00614 1.6e-96 ybaT E Amino acid permease
KPIMHEKK_00615 1.7e-07 S LPXTG cell wall anchor motif
KPIMHEKK_00616 4.4e-146 S Putative ABC-transporter type IV
KPIMHEKK_00617 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KPIMHEKK_00618 4.4e-234 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KPIMHEKK_00619 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KPIMHEKK_00620 1.2e-232 oppA E ABC transporter substrate-binding protein
KPIMHEKK_00621 2.1e-95 oppA E ABC transporter substrate-binding protein
KPIMHEKK_00622 3.2e-176 K AI-2E family transporter
KPIMHEKK_00623 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KPIMHEKK_00624 4.1e-18
KPIMHEKK_00625 4.1e-245 G Major Facilitator
KPIMHEKK_00626 1.3e-79 E Zn peptidase
KPIMHEKK_00627 1e-41 ps115 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_00628 5.6e-45
KPIMHEKK_00629 4.5e-66 S Bacteriocin helveticin-J
KPIMHEKK_00630 1.7e-66 S SLAP domain
KPIMHEKK_00631 5.8e-45
KPIMHEKK_00632 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
KPIMHEKK_00633 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KPIMHEKK_00634 1.7e-174 ABC-SBP S ABC transporter
KPIMHEKK_00635 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KPIMHEKK_00636 1.6e-48 P CorA-like Mg2+ transporter protein
KPIMHEKK_00637 5.2e-75 P CorA-like Mg2+ transporter protein
KPIMHEKK_00638 3.5e-160 yvgN C Aldo keto reductase
KPIMHEKK_00639 0.0 tetP J elongation factor G
KPIMHEKK_00640 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
KPIMHEKK_00641 1.2e-134 EGP Major facilitator Superfamily
KPIMHEKK_00643 0.0 XK27_08315 M Sulfatase
KPIMHEKK_00644 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KPIMHEKK_00645 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPIMHEKK_00646 1.4e-98 G Aldose 1-epimerase
KPIMHEKK_00647 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPIMHEKK_00648 2.1e-116
KPIMHEKK_00649 2.1e-130
KPIMHEKK_00650 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
KPIMHEKK_00651 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KPIMHEKK_00652 0.0 yjbQ P TrkA C-terminal domain protein
KPIMHEKK_00653 6.5e-180 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KPIMHEKK_00654 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KPIMHEKK_00656 6.3e-132 S SLAP domain
KPIMHEKK_00657 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KPIMHEKK_00658 5.1e-226 N Uncharacterized conserved protein (DUF2075)
KPIMHEKK_00659 4.8e-205 pbpX1 V Beta-lactamase
KPIMHEKK_00660 0.0 L Helicase C-terminal domain protein
KPIMHEKK_00661 1.3e-273 E amino acid
KPIMHEKK_00662 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
KPIMHEKK_00665 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPIMHEKK_00666 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KPIMHEKK_00667 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KPIMHEKK_00668 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KPIMHEKK_00669 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPIMHEKK_00670 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KPIMHEKK_00671 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KPIMHEKK_00672 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KPIMHEKK_00673 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KPIMHEKK_00674 2.9e-107 IQ reductase
KPIMHEKK_00675 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KPIMHEKK_00676 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPIMHEKK_00677 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPIMHEKK_00678 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPIMHEKK_00679 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KPIMHEKK_00680 1.6e-73 marR K Transcriptional regulator, MarR family
KPIMHEKK_00681 1e-57
KPIMHEKK_00682 3.1e-48 S Domain of unknown function (DUF4811)
KPIMHEKK_00683 1.4e-262 lmrB EGP Major facilitator Superfamily
KPIMHEKK_00684 4.2e-77 K MerR HTH family regulatory protein
KPIMHEKK_00685 3.1e-139 S Cysteine-rich secretory protein family
KPIMHEKK_00686 4.6e-274 ycaM E amino acid
KPIMHEKK_00687 2.8e-290
KPIMHEKK_00689 3.6e-188 cggR K Putative sugar-binding domain
KPIMHEKK_00690 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KPIMHEKK_00691 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KPIMHEKK_00692 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KPIMHEKK_00693 2.6e-138 S TerB-C domain
KPIMHEKK_00694 1.4e-245 P P-loop Domain of unknown function (DUF2791)
KPIMHEKK_00695 0.0 lhr L DEAD DEAH box helicase
KPIMHEKK_00696 1.4e-60
KPIMHEKK_00697 4.3e-228 amtB P ammonium transporter
KPIMHEKK_00698 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KPIMHEKK_00700 6.6e-61 psiE S Phosphate-starvation-inducible E
KPIMHEKK_00701 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
KPIMHEKK_00702 2.9e-69 S Iron-sulphur cluster biosynthesis
KPIMHEKK_00704 2.3e-30
KPIMHEKK_00705 2.6e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
KPIMHEKK_00706 6.2e-12
KPIMHEKK_00707 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPIMHEKK_00708 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPIMHEKK_00709 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPIMHEKK_00710 5.8e-78 M LysM domain protein
KPIMHEKK_00711 4.7e-159 D nuclear chromosome segregation
KPIMHEKK_00712 1.2e-105 G Phosphoglycerate mutase family
KPIMHEKK_00713 2.6e-89 G Histidine phosphatase superfamily (branch 1)
KPIMHEKK_00714 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
KPIMHEKK_00715 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KPIMHEKK_00717 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KPIMHEKK_00719 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KPIMHEKK_00720 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
KPIMHEKK_00721 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KPIMHEKK_00722 4.4e-144 K SIS domain
KPIMHEKK_00723 4.8e-44 slpX S SLAP domain
KPIMHEKK_00724 5.3e-167 slpX S SLAP domain
KPIMHEKK_00725 1.3e-22 3.6.4.12 S transposase or invertase
KPIMHEKK_00726 6.6e-11
KPIMHEKK_00727 3.2e-240 npr 1.11.1.1 C NADH oxidase
KPIMHEKK_00730 4.4e-239 oppA2 E ABC transporter, substratebinding protein
KPIMHEKK_00731 3.4e-45 oppA2 E ABC transporter, substratebinding protein
KPIMHEKK_00732 3.3e-179
KPIMHEKK_00733 1.3e-125 gntR1 K UTRA
KPIMHEKK_00734 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
KPIMHEKK_00735 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KPIMHEKK_00736 1.7e-204 csaB M Glycosyl transferases group 1
KPIMHEKK_00737 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPIMHEKK_00738 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KPIMHEKK_00739 1.4e-204 tnpB L Putative transposase DNA-binding domain
KPIMHEKK_00740 0.0 pacL 3.6.3.8 P P-type ATPase
KPIMHEKK_00741 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KPIMHEKK_00742 6e-258 epsU S Polysaccharide biosynthesis protein
KPIMHEKK_00743 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
KPIMHEKK_00744 2.6e-82 ydcK S Belongs to the SprT family
KPIMHEKK_00746 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
KPIMHEKK_00747 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KPIMHEKK_00748 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPIMHEKK_00749 5.8e-203 camS S sex pheromone
KPIMHEKK_00750 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPIMHEKK_00751 6.4e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KPIMHEKK_00752 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPIMHEKK_00753 2.7e-171 yegS 2.7.1.107 G Lipid kinase
KPIMHEKK_00754 4.3e-108 ybhL S Belongs to the BI1 family
KPIMHEKK_00755 2.6e-57
KPIMHEKK_00756 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
KPIMHEKK_00757 2.8e-244 nhaC C Na H antiporter NhaC
KPIMHEKK_00758 6.3e-201 pbpX V Beta-lactamase
KPIMHEKK_00759 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPIMHEKK_00760 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
KPIMHEKK_00765 1.9e-259 emrY EGP Major facilitator Superfamily
KPIMHEKK_00766 2e-91 yxdD K Bacterial regulatory proteins, tetR family
KPIMHEKK_00767 0.0 4.2.1.53 S Myosin-crossreactive antigen
KPIMHEKK_00768 5.5e-148 S cog cog1373
KPIMHEKK_00770 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPIMHEKK_00771 3.5e-175 S Cysteine-rich secretory protein family
KPIMHEKK_00772 1.6e-41
KPIMHEKK_00773 2.6e-118 M NlpC/P60 family
KPIMHEKK_00774 1.4e-136 M NlpC P60 family protein
KPIMHEKK_00775 5e-88 M NlpC/P60 family
KPIMHEKK_00776 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
KPIMHEKK_00777 3.9e-42
KPIMHEKK_00778 2.9e-279 S O-antigen ligase like membrane protein
KPIMHEKK_00779 3.3e-112
KPIMHEKK_00780 4.7e-221 tnpB L Putative transposase DNA-binding domain
KPIMHEKK_00781 5.5e-77 nrdI F NrdI Flavodoxin like
KPIMHEKK_00782 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPIMHEKK_00783 2.5e-68
KPIMHEKK_00784 9.1e-112 yvpB S Peptidase_C39 like family
KPIMHEKK_00785 1.1e-83 S Threonine/Serine exporter, ThrE
KPIMHEKK_00786 2.4e-136 thrE S Putative threonine/serine exporter
KPIMHEKK_00787 8.9e-292 S ABC transporter
KPIMHEKK_00788 8.3e-58
KPIMHEKK_00789 5e-72 rimL J Acetyltransferase (GNAT) domain
KPIMHEKK_00790 1.4e-34
KPIMHEKK_00791 1.2e-30
KPIMHEKK_00792 1.8e-111 S Protein of unknown function (DUF554)
KPIMHEKK_00793 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KPIMHEKK_00794 0.0 pepF E oligoendopeptidase F
KPIMHEKK_00795 2.9e-31
KPIMHEKK_00796 1.3e-69 doc S Prophage maintenance system killer protein
KPIMHEKK_00799 4.6e-27 S Enterocin A Immunity
KPIMHEKK_00800 1.7e-22 blpT
KPIMHEKK_00801 8.4e-265 S Fibronectin type III domain
KPIMHEKK_00802 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPIMHEKK_00803 3.4e-53
KPIMHEKK_00805 4.6e-257 pepC 3.4.22.40 E aminopeptidase
KPIMHEKK_00806 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KPIMHEKK_00807 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPIMHEKK_00808 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KPIMHEKK_00809 7.2e-56 yheA S Belongs to the UPF0342 family
KPIMHEKK_00810 1e-226 yhaO L Ser Thr phosphatase family protein
KPIMHEKK_00811 0.0 L AAA domain
KPIMHEKK_00812 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
KPIMHEKK_00813 2.9e-23
KPIMHEKK_00814 2.4e-51 S Domain of unknown function DUF1829
KPIMHEKK_00815 1.1e-265
KPIMHEKK_00816 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
KPIMHEKK_00817 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KPIMHEKK_00818 3.9e-25
KPIMHEKK_00819 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
KPIMHEKK_00820 5.7e-135 ecsA V ABC transporter, ATP-binding protein
KPIMHEKK_00821 6.5e-221 ecsB U ABC transporter
KPIMHEKK_00822 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KPIMHEKK_00824 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KPIMHEKK_00825 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPIMHEKK_00826 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KPIMHEKK_00827 6.9e-218 mepA V MATE efflux family protein
KPIMHEKK_00828 1.8e-176 S SLAP domain
KPIMHEKK_00829 4.4e-283 M Peptidase family M1 domain
KPIMHEKK_00830 4.5e-188 S Bacteriocin helveticin-J
KPIMHEKK_00831 8e-51 L RelB antitoxin
KPIMHEKK_00832 7.4e-105 qmcA O prohibitin homologues
KPIMHEKK_00833 3.5e-25 qmcA O prohibitin homologues
KPIMHEKK_00834 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPIMHEKK_00835 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KPIMHEKK_00836 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPIMHEKK_00837 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPIMHEKK_00838 5.1e-251 dnaB L Replication initiation and membrane attachment
KPIMHEKK_00839 1.3e-168 dnaI L Primosomal protein DnaI
KPIMHEKK_00840 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPIMHEKK_00841 4.3e-75
KPIMHEKK_00842 1.2e-16
KPIMHEKK_00843 2.1e-255 S Archaea bacterial proteins of unknown function
KPIMHEKK_00844 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KPIMHEKK_00845 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
KPIMHEKK_00846 1e-24
KPIMHEKK_00847 9.5e-26
KPIMHEKK_00848 2.5e-33
KPIMHEKK_00849 1.4e-53 S Enterocin A Immunity
KPIMHEKK_00850 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KPIMHEKK_00851 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPIMHEKK_00852 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
KPIMHEKK_00853 9.6e-121 K response regulator
KPIMHEKK_00855 0.0 V ABC transporter
KPIMHEKK_00856 4.2e-144 V ABC transporter, ATP-binding protein
KPIMHEKK_00857 1.2e-145 V ABC transporter, ATP-binding protein
KPIMHEKK_00858 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
KPIMHEKK_00859 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KPIMHEKK_00860 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
KPIMHEKK_00861 8.5e-154 spo0J K Belongs to the ParB family
KPIMHEKK_00862 3.4e-138 soj D Sporulation initiation inhibitor
KPIMHEKK_00863 1.5e-147 noc K Belongs to the ParB family
KPIMHEKK_00864 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KPIMHEKK_00865 3e-53 cvpA S Colicin V production protein
KPIMHEKK_00866 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPIMHEKK_00867 6e-151 3.1.3.48 T Tyrosine phosphatase family
KPIMHEKK_00868 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
KPIMHEKK_00869 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
KPIMHEKK_00870 2.4e-110 K WHG domain
KPIMHEKK_00871 3e-37
KPIMHEKK_00872 6.4e-71 scrR K Periplasmic binding protein domain
KPIMHEKK_00873 5.5e-36
KPIMHEKK_00874 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KPIMHEKK_00875 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KPIMHEKK_00876 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KPIMHEKK_00877 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KPIMHEKK_00878 0.0 lacS G Transporter
KPIMHEKK_00879 3.2e-165 lacR K Transcriptional regulator
KPIMHEKK_00880 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KPIMHEKK_00881 3.5e-145 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KPIMHEKK_00882 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPIMHEKK_00883 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
KPIMHEKK_00884 2e-106 K Transcriptional regulator, AbiEi antitoxin
KPIMHEKK_00885 1.2e-188 K Periplasmic binding protein-like domain
KPIMHEKK_00886 2e-49 L PFAM transposase, IS4 family protein
KPIMHEKK_00887 1.7e-213 1.3.5.4 C FAD binding domain
KPIMHEKK_00888 3.4e-126 1.3.5.4 C FAD binding domain
KPIMHEKK_00890 5.2e-104
KPIMHEKK_00891 0.0 1.3.5.4 C FAD binding domain
KPIMHEKK_00892 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KPIMHEKK_00893 1.7e-249 yhdP S Transporter associated domain
KPIMHEKK_00894 3.9e-119 C nitroreductase
KPIMHEKK_00895 2.1e-39
KPIMHEKK_00896 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KPIMHEKK_00897 1.6e-80
KPIMHEKK_00898 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
KPIMHEKK_00899 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
KPIMHEKK_00900 5.4e-147 S hydrolase
KPIMHEKK_00901 2e-160 rssA S Phospholipase, patatin family
KPIMHEKK_00902 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KPIMHEKK_00903 3.1e-136 glcR K DeoR C terminal sensor domain
KPIMHEKK_00904 2.5e-59 S Enterocin A Immunity
KPIMHEKK_00905 1.2e-154 S hydrolase
KPIMHEKK_00906 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
KPIMHEKK_00907 9.1e-175 rihB 3.2.2.1 F Nucleoside
KPIMHEKK_00908 0.0 kup P Transport of potassium into the cell
KPIMHEKK_00909 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPIMHEKK_00910 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPIMHEKK_00911 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
KPIMHEKK_00912 1.3e-235 G Bacterial extracellular solute-binding protein
KPIMHEKK_00913 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
KPIMHEKK_00914 5.6e-86
KPIMHEKK_00915 1.1e-164 S Protein of unknown function (DUF2974)
KPIMHEKK_00916 4.7e-109 glnP P ABC transporter permease
KPIMHEKK_00917 3.7e-90 gluC P ABC transporter permease
KPIMHEKK_00918 1.2e-146 glnH ET ABC transporter substrate-binding protein
KPIMHEKK_00919 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KPIMHEKK_00920 3.8e-46 udk 2.7.1.48 F Zeta toxin
KPIMHEKK_00921 1e-44 udk 2.7.1.48 F Zeta toxin
KPIMHEKK_00922 1e-246 G MFS/sugar transport protein
KPIMHEKK_00923 1.6e-100 S ABC-type cobalt transport system, permease component
KPIMHEKK_00924 0.0 V ABC transporter transmembrane region
KPIMHEKK_00925 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
KPIMHEKK_00926 1.4e-80 K Transcriptional regulator, MarR family
KPIMHEKK_00927 1.9e-147 glnH ET ABC transporter
KPIMHEKK_00928 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
KPIMHEKK_00929 8.6e-243 steT E amino acid
KPIMHEKK_00930 2.4e-26 steT E amino acid
KPIMHEKK_00931 2.8e-202 steT E amino acid
KPIMHEKK_00932 2.7e-138
KPIMHEKK_00933 5.9e-174 S Aldo keto reductase
KPIMHEKK_00934 2.2e-311 ybiT S ABC transporter, ATP-binding protein
KPIMHEKK_00941 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
KPIMHEKK_00942 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
KPIMHEKK_00943 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPIMHEKK_00944 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KPIMHEKK_00945 1.7e-29 secG U Preprotein translocase
KPIMHEKK_00946 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KPIMHEKK_00947 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KPIMHEKK_00948 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KPIMHEKK_00949 7.4e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KPIMHEKK_00950 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KPIMHEKK_00951 3.6e-163 yihY S Belongs to the UPF0761 family
KPIMHEKK_00952 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
KPIMHEKK_00953 4.1e-80 fld C Flavodoxin
KPIMHEKK_00954 7e-87 gtcA S Teichoic acid glycosylation protein
KPIMHEKK_00955 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KPIMHEKK_00956 3.2e-181 ccpA K catabolite control protein A
KPIMHEKK_00957 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KPIMHEKK_00958 4.3e-55
KPIMHEKK_00959 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KPIMHEKK_00960 2.1e-92 yutD S Protein of unknown function (DUF1027)
KPIMHEKK_00961 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KPIMHEKK_00962 3.7e-100 S Protein of unknown function (DUF1461)
KPIMHEKK_00963 6.8e-116 dedA S SNARE-like domain protein
KPIMHEKK_00964 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KPIMHEKK_00965 1.3e-277 arlS 2.7.13.3 T Histidine kinase
KPIMHEKK_00966 1.2e-126 K response regulator
KPIMHEKK_00967 4.7e-97 yceD S Uncharacterized ACR, COG1399
KPIMHEKK_00968 1.7e-215 ylbM S Belongs to the UPF0348 family
KPIMHEKK_00969 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KPIMHEKK_00970 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KPIMHEKK_00971 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPIMHEKK_00972 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
KPIMHEKK_00973 4.2e-84 yqeG S HAD phosphatase, family IIIA
KPIMHEKK_00974 9.2e-201 tnpB L Putative transposase DNA-binding domain
KPIMHEKK_00975 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KPIMHEKK_00976 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPIMHEKK_00977 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KPIMHEKK_00978 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KPIMHEKK_00979 4e-98 rihB 3.2.2.1 F Nucleoside
KPIMHEKK_00980 6.4e-31
KPIMHEKK_00981 2.7e-37
KPIMHEKK_00982 1.3e-18
KPIMHEKK_00983 2.7e-46
KPIMHEKK_00984 1.5e-58 M LysM domain
KPIMHEKK_00985 1e-220 3.4.14.13 M Phage tail tape measure protein TP901
KPIMHEKK_00987 2.9e-09
KPIMHEKK_00988 9.3e-29
KPIMHEKK_00989 3.5e-103 Z012_02110 S Protein of unknown function (DUF3383)
KPIMHEKK_00990 3.3e-31
KPIMHEKK_00991 1.6e-25
KPIMHEKK_00992 1.1e-28
KPIMHEKK_00993 1.6e-19 S Protein of unknown function (DUF4054)
KPIMHEKK_00994 2.4e-93 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
KPIMHEKK_00995 4.1e-34
KPIMHEKK_00996 1.6e-57 S Uncharacterized protein conserved in bacteria (DUF2213)
KPIMHEKK_00997 5e-12 S Lysin motif
KPIMHEKK_00998 1.3e-47 S Phage Mu protein F like protein
KPIMHEKK_00999 6.2e-135 S Protein of unknown function (DUF1073)
KPIMHEKK_01000 1.1e-201 S Terminase-like family
KPIMHEKK_01001 3e-19 ps333 L Terminase small subunit
KPIMHEKK_01004 3.3e-09 arpU S Phage transcriptional regulator, ArpU family
KPIMHEKK_01007 3.8e-219 XK27_11280 S Psort location CytoplasmicMembrane, score
KPIMHEKK_01015 1.2e-100 L Helix-turn-helix domain
KPIMHEKK_01016 5.3e-131 S ERF superfamily
KPIMHEKK_01017 6.1e-128 S Protein of unknown function (DUF1351)
KPIMHEKK_01018 4.6e-45
KPIMHEKK_01020 5.5e-18
KPIMHEKK_01021 1.8e-31 S Helix-turn-helix domain
KPIMHEKK_01027 1.4e-85 S AntA/AntB antirepressor
KPIMHEKK_01029 3.7e-13
KPIMHEKK_01030 3.1e-12
KPIMHEKK_01031 3.7e-18 ps115 K sequence-specific DNA binding
KPIMHEKK_01032 4.7e-15 S Pfam:Peptidase_M78
KPIMHEKK_01033 1.2e-54 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KPIMHEKK_01034 6.2e-12
KPIMHEKK_01035 3.7e-93 sip L Belongs to the 'phage' integrase family
KPIMHEKK_01036 6.3e-47 U TraM recognition site of TraD and TraG
KPIMHEKK_01040 7.9e-31 M domain protein
KPIMHEKK_01041 6.8e-15 S SLAP domain
KPIMHEKK_01042 6e-42 M domain protein
KPIMHEKK_01044 1.4e-24 srtA 3.4.22.70 M sortase family
KPIMHEKK_01045 2.4e-21 S SLAP domain
KPIMHEKK_01051 3.3e-11 S Single-strand binding protein family
KPIMHEKK_01052 1.6e-10
KPIMHEKK_01060 1.5e-26 S Domain of unknown function (DUF771)
KPIMHEKK_01061 4e-21 K Conserved phage C-terminus (Phg_2220_C)
KPIMHEKK_01063 4.1e-09 S Arc-like DNA binding domain
KPIMHEKK_01065 9.8e-26 K Helix-turn-helix domain
KPIMHEKK_01066 2.6e-21 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_01067 1.1e-17 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_01068 2.6e-09 S Pfam:DUF955
KPIMHEKK_01069 8.9e-67 L Belongs to the 'phage' integrase family
KPIMHEKK_01070 1.2e-10
KPIMHEKK_01071 2.8e-65 K LytTr DNA-binding domain
KPIMHEKK_01072 1.2e-49 S Protein of unknown function (DUF3021)
KPIMHEKK_01073 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KPIMHEKK_01074 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KPIMHEKK_01075 6e-132 S membrane transporter protein
KPIMHEKK_01076 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
KPIMHEKK_01077 7.3e-161 czcD P cation diffusion facilitator family transporter
KPIMHEKK_01078 1.4e-23
KPIMHEKK_01079 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPIMHEKK_01080 5.4e-183 S AAA domain
KPIMHEKK_01081 7.3e-44
KPIMHEKK_01082 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
KPIMHEKK_01083 4.1e-52
KPIMHEKK_01084 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KPIMHEKK_01085 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPIMHEKK_01086 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPIMHEKK_01087 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPIMHEKK_01088 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KPIMHEKK_01089 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPIMHEKK_01090 1.2e-94 sigH K Belongs to the sigma-70 factor family
KPIMHEKK_01091 1.7e-34
KPIMHEKK_01092 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KPIMHEKK_01093 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPIMHEKK_01094 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KPIMHEKK_01095 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
KPIMHEKK_01096 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPIMHEKK_01097 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KPIMHEKK_01098 2.8e-157 pstS P Phosphate
KPIMHEKK_01099 1.9e-162 pstC P probably responsible for the translocation of the substrate across the membrane
KPIMHEKK_01100 6.5e-154 pstA P Phosphate transport system permease protein PstA
KPIMHEKK_01101 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPIMHEKK_01102 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPIMHEKK_01103 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
KPIMHEKK_01104 2.8e-90 L An automated process has identified a potential problem with this gene model
KPIMHEKK_01105 9.3e-86
KPIMHEKK_01106 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPIMHEKK_01107 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
KPIMHEKK_01108 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPIMHEKK_01109 4.4e-140 ypuA S Protein of unknown function (DUF1002)
KPIMHEKK_01110 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
KPIMHEKK_01111 7.3e-126 S Alpha/beta hydrolase family
KPIMHEKK_01112 5.2e-08
KPIMHEKK_01113 3e-89 ntd 2.4.2.6 F Nucleoside
KPIMHEKK_01114 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KPIMHEKK_01115 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
KPIMHEKK_01116 2.2e-82 uspA T universal stress protein
KPIMHEKK_01118 1.2e-161 phnD P Phosphonate ABC transporter
KPIMHEKK_01119 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KPIMHEKK_01120 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KPIMHEKK_01121 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KPIMHEKK_01122 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
KPIMHEKK_01123 8.9e-240 L transposase, IS605 OrfB family
KPIMHEKK_01124 2.1e-28 S Peptidase propeptide and YPEB domain
KPIMHEKK_01125 2.4e-60 ypaA S Protein of unknown function (DUF1304)
KPIMHEKK_01126 2.3e-309 oppA3 E ABC transporter, substratebinding protein
KPIMHEKK_01127 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KPIMHEKK_01128 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
KPIMHEKK_01129 1.4e-36 S Cytochrome B5
KPIMHEKK_01130 6e-168 arbZ I Phosphate acyltransferases
KPIMHEKK_01131 1.6e-182 arbY M Glycosyl transferase family 8
KPIMHEKK_01132 5e-184 arbY M Glycosyl transferase family 8
KPIMHEKK_01133 5e-156 arbx M Glycosyl transferase family 8
KPIMHEKK_01134 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
KPIMHEKK_01136 4.9e-34
KPIMHEKK_01138 4.8e-131 K response regulator
KPIMHEKK_01139 2.2e-305 vicK 2.7.13.3 T Histidine kinase
KPIMHEKK_01140 1.6e-257 yycH S YycH protein
KPIMHEKK_01141 3.4e-149 yycI S YycH protein
KPIMHEKK_01142 4.1e-147 vicX 3.1.26.11 S domain protein
KPIMHEKK_01143 1.6e-161 htrA 3.4.21.107 O serine protease
KPIMHEKK_01144 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPIMHEKK_01145 1.5e-102 GM NmrA-like family
KPIMHEKK_01146 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPIMHEKK_01147 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KPIMHEKK_01148 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KPIMHEKK_01149 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPIMHEKK_01150 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KPIMHEKK_01151 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KPIMHEKK_01152 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KPIMHEKK_01153 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KPIMHEKK_01154 3.7e-250 lctP C L-lactate permease
KPIMHEKK_01155 3.1e-148 glcU U sugar transport
KPIMHEKK_01156 7.1e-46
KPIMHEKK_01157 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KPIMHEKK_01158 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KPIMHEKK_01159 3.7e-19 S Alpha beta hydrolase
KPIMHEKK_01160 1.2e-63 S Alpha beta hydrolase
KPIMHEKK_01161 1.9e-37
KPIMHEKK_01162 7e-50
KPIMHEKK_01163 5.1e-12 S haloacid dehalogenase-like hydrolase
KPIMHEKK_01164 1.4e-95 sip L Belongs to the 'phage' integrase family
KPIMHEKK_01167 4.8e-17 S protein disulfide oxidoreductase activity
KPIMHEKK_01168 6.6e-11 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_01171 3.2e-10
KPIMHEKK_01176 2.2e-53 S Protein of unknown function (DUF1351)
KPIMHEKK_01177 1.6e-44 S ERF superfamily
KPIMHEKK_01178 2.7e-31 K Helix-turn-helix domain
KPIMHEKK_01180 1.6e-31 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KPIMHEKK_01181 4e-65 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KPIMHEKK_01182 1.5e-21 radC L DNA repair protein
KPIMHEKK_01188 2.7e-33 Q DNA (cytosine-5-)-methyltransferase activity
KPIMHEKK_01193 2.2e-67 S ORF6C domain
KPIMHEKK_01195 5.3e-36 S VRR_NUC
KPIMHEKK_01196 3.4e-09
KPIMHEKK_01202 1.1e-20 S N-methyltransferase activity
KPIMHEKK_01205 9.6e-187 S Terminase-like family
KPIMHEKK_01206 3.3e-91 S Protein of unknown function (DUF1073)
KPIMHEKK_01207 1.3e-55 S Phage Mu protein F like protein
KPIMHEKK_01208 4.8e-20 S Lysin motif
KPIMHEKK_01209 1.3e-53 S Uncharacterized protein conserved in bacteria (DUF2213)
KPIMHEKK_01210 1e-22
KPIMHEKK_01211 2.9e-36 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
KPIMHEKK_01212 1.6e-27 S Protein of unknown function (DUF4054)
KPIMHEKK_01213 7.7e-42
KPIMHEKK_01214 2.7e-10
KPIMHEKK_01215 1.6e-27
KPIMHEKK_01216 1.7e-133 Z012_02110 S Protein of unknown function (DUF3383)
KPIMHEKK_01217 1.3e-11
KPIMHEKK_01218 1.1e-11
KPIMHEKK_01219 2.5e-197 M Phage tail tape measure protein TP901
KPIMHEKK_01220 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
KPIMHEKK_01221 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KPIMHEKK_01224 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KPIMHEKK_01225 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KPIMHEKK_01226 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPIMHEKK_01228 1.6e-25 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_01229 1.2e-11
KPIMHEKK_01230 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
KPIMHEKK_01231 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KPIMHEKK_01232 2e-264 lctP C L-lactate permease
KPIMHEKK_01233 5e-129 znuB U ABC 3 transport family
KPIMHEKK_01234 1.6e-117 fhuC P ABC transporter
KPIMHEKK_01235 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
KPIMHEKK_01236 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
KPIMHEKK_01237 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
KPIMHEKK_01238 8.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KPIMHEKK_01239 1.8e-136 fruR K DeoR C terminal sensor domain
KPIMHEKK_01240 1.8e-218 natB CP ABC-2 family transporter protein
KPIMHEKK_01241 1.1e-164 natA S ABC transporter, ATP-binding protein
KPIMHEKK_01242 1.7e-67
KPIMHEKK_01243 2e-23
KPIMHEKK_01244 8.2e-31 yozG K Transcriptional regulator
KPIMHEKK_01245 3.7e-83
KPIMHEKK_01246 3e-21
KPIMHEKK_01250 2.2e-129 blpT
KPIMHEKK_01251 1.4e-107 M Transport protein ComB
KPIMHEKK_01252 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KPIMHEKK_01253 1.7e-193 S TerB-C domain
KPIMHEKK_01254 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KPIMHEKK_01255 3.9e-298 V ABC transporter transmembrane region
KPIMHEKK_01256 2.3e-156 K Helix-turn-helix XRE-family like proteins
KPIMHEKK_01257 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KPIMHEKK_01258 2.1e-32
KPIMHEKK_01259 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
KPIMHEKK_01260 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
KPIMHEKK_01261 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
KPIMHEKK_01262 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPIMHEKK_01263 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
KPIMHEKK_01264 0.0 mtlR K Mga helix-turn-helix domain
KPIMHEKK_01265 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KPIMHEKK_01266 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KPIMHEKK_01267 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KPIMHEKK_01268 6.8e-243 cycA E Amino acid permease
KPIMHEKK_01269 1.3e-85 maa S transferase hexapeptide repeat
KPIMHEKK_01270 3.3e-158 K Transcriptional regulator
KPIMHEKK_01271 1.1e-62 manO S Domain of unknown function (DUF956)
KPIMHEKK_01272 1e-173 manN G system, mannose fructose sorbose family IID component
KPIMHEKK_01273 1.7e-129 manY G PTS system
KPIMHEKK_01274 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KPIMHEKK_01275 5.6e-36
KPIMHEKK_01276 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPIMHEKK_01277 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
KPIMHEKK_01278 2.8e-135
KPIMHEKK_01279 1.3e-258 glnPH2 P ABC transporter permease
KPIMHEKK_01280 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KPIMHEKK_01281 6.4e-224 S Cysteine-rich secretory protein family
KPIMHEKK_01282 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KPIMHEKK_01283 1.4e-112
KPIMHEKK_01284 6.3e-202 yibE S overlaps another CDS with the same product name
KPIMHEKK_01285 4.9e-129 yibF S overlaps another CDS with the same product name
KPIMHEKK_01286 2.5e-144 I alpha/beta hydrolase fold
KPIMHEKK_01287 0.0 G Belongs to the glycosyl hydrolase 31 family
KPIMHEKK_01288 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KPIMHEKK_01290 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
KPIMHEKK_01293 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPIMHEKK_01294 8.5e-260 qacA EGP Major facilitator Superfamily
KPIMHEKK_01296 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
KPIMHEKK_01297 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KPIMHEKK_01298 1.8e-119 S Putative esterase
KPIMHEKK_01299 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
KPIMHEKK_01300 3.4e-195 S Bacterial protein of unknown function (DUF871)
KPIMHEKK_01301 3.7e-130 ybbH_2 K rpiR family
KPIMHEKK_01302 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
KPIMHEKK_01303 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KPIMHEKK_01304 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KPIMHEKK_01305 6e-268 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KPIMHEKK_01306 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KPIMHEKK_01307 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KPIMHEKK_01308 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KPIMHEKK_01309 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
KPIMHEKK_01310 6.2e-43 1.3.5.4 C FAD binding domain
KPIMHEKK_01311 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KPIMHEKK_01312 2.8e-168 K LysR substrate binding domain
KPIMHEKK_01313 1.1e-121 3.6.1.27 I Acid phosphatase homologues
KPIMHEKK_01314 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPIMHEKK_01315 4.7e-275 ytgP S Polysaccharide biosynthesis protein
KPIMHEKK_01316 6.3e-192 oppA E ABC transporter, substratebinding protein
KPIMHEKK_01317 1.3e-30
KPIMHEKK_01318 4.2e-145 pstS P Phosphate
KPIMHEKK_01319 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KPIMHEKK_01320 1.2e-152 pstA P Phosphate transport system permease protein PstA
KPIMHEKK_01321 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPIMHEKK_01322 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
KPIMHEKK_01323 9.5e-121 T Transcriptional regulatory protein, C terminal
KPIMHEKK_01324 1.1e-282 phoR 2.7.13.3 T Histidine kinase
KPIMHEKK_01325 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPIMHEKK_01326 0.0 uup S ABC transporter, ATP-binding protein
KPIMHEKK_01327 2.7e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KPIMHEKK_01328 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KPIMHEKK_01329 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KPIMHEKK_01330 7.7e-22
KPIMHEKK_01331 9.3e-64 L PFAM IS66 Orf2 family protein
KPIMHEKK_01332 8.7e-34 S Transposase C of IS166 homeodomain
KPIMHEKK_01333 1.9e-245 L Transposase IS66 family
KPIMHEKK_01334 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KPIMHEKK_01335 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KPIMHEKK_01336 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KPIMHEKK_01337 2.2e-85 S ECF transporter, substrate-specific component
KPIMHEKK_01338 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
KPIMHEKK_01339 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPIMHEKK_01340 1.8e-59 yabA L Involved in initiation control of chromosome replication
KPIMHEKK_01341 1.5e-155 holB 2.7.7.7 L DNA polymerase III
KPIMHEKK_01342 8.9e-53 yaaQ S Cyclic-di-AMP receptor
KPIMHEKK_01343 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPIMHEKK_01344 1.1e-34 S Protein of unknown function (DUF2508)
KPIMHEKK_01345 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPIMHEKK_01346 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KPIMHEKK_01347 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KPIMHEKK_01348 5.7e-106 2.4.1.58 GT8 M family 8
KPIMHEKK_01349 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPIMHEKK_01350 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KPIMHEKK_01351 9e-26
KPIMHEKK_01352 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
KPIMHEKK_01353 1.9e-139 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
KPIMHEKK_01354 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KPIMHEKK_01355 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPIMHEKK_01356 1.5e-11 GT2,GT4 M family 8
KPIMHEKK_01357 2.9e-277 V ABC transporter transmembrane region
KPIMHEKK_01358 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KPIMHEKK_01359 3.1e-130 T Transcriptional regulatory protein, C terminal
KPIMHEKK_01360 5.2e-187 T GHKL domain
KPIMHEKK_01361 3.4e-76 S Peptidase propeptide and YPEB domain
KPIMHEKK_01362 2.5e-72 S Peptidase propeptide and YPEB domain
KPIMHEKK_01363 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KPIMHEKK_01364 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
KPIMHEKK_01365 7e-68 V ABC transporter transmembrane region
KPIMHEKK_01366 9e-161 V ABC transporter transmembrane region
KPIMHEKK_01367 8.1e-175 ulaG S Beta-lactamase superfamily domain
KPIMHEKK_01368 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KPIMHEKK_01369 1.3e-231 ulaA S PTS system sugar-specific permease component
KPIMHEKK_01370 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
KPIMHEKK_01371 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
KPIMHEKK_01372 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
KPIMHEKK_01373 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KPIMHEKK_01374 5.2e-68 L haloacid dehalogenase-like hydrolase
KPIMHEKK_01375 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KPIMHEKK_01376 1.4e-16 L Transposase
KPIMHEKK_01377 1.9e-12 L Transposase
KPIMHEKK_01378 5.9e-13 K Acetyltransferase (GNAT) domain
KPIMHEKK_01379 2.2e-113 S SLAP domain
KPIMHEKK_01380 2.6e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KPIMHEKK_01381 5.7e-46 S An automated process has identified a potential problem with this gene model
KPIMHEKK_01382 3e-137 S Protein of unknown function (DUF3100)
KPIMHEKK_01383 4e-245 3.5.1.47 S Peptidase dimerisation domain
KPIMHEKK_01384 5.8e-230 Q Imidazolonepropionase and related amidohydrolases
KPIMHEKK_01385 0.0 oppA E ABC transporter
KPIMHEKK_01386 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
KPIMHEKK_01387 0.0 mco Q Multicopper oxidase
KPIMHEKK_01388 1.9e-25
KPIMHEKK_01389 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
KPIMHEKK_01390 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
KPIMHEKK_01391 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPIMHEKK_01392 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPIMHEKK_01393 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPIMHEKK_01394 1.9e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KPIMHEKK_01395 5.7e-69 rplI J Binds to the 23S rRNA
KPIMHEKK_01396 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KPIMHEKK_01397 1.7e-301 oppA E ABC transporter, substratebinding protein
KPIMHEKK_01398 1.6e-310 oppA E ABC transporter, substratebinding protein
KPIMHEKK_01399 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KPIMHEKK_01400 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPIMHEKK_01401 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPIMHEKK_01402 2.7e-199 oppD P Belongs to the ABC transporter superfamily
KPIMHEKK_01403 1.9e-175 oppF P Belongs to the ABC transporter superfamily
KPIMHEKK_01404 1.4e-256 pepC 3.4.22.40 E aminopeptidase
KPIMHEKK_01405 3.9e-72 hsp O Belongs to the small heat shock protein (HSP20) family
KPIMHEKK_01406 1.3e-28 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPIMHEKK_01407 1.9e-47 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KPIMHEKK_01408 1e-149 D Alpha beta
KPIMHEKK_01409 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPIMHEKK_01410 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
KPIMHEKK_01411 8.3e-143 licT K CAT RNA binding domain
KPIMHEKK_01412 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KPIMHEKK_01413 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPIMHEKK_01414 1.6e-118
KPIMHEKK_01415 1.8e-75 K Penicillinase repressor
KPIMHEKK_01416 1.4e-147 S hydrolase
KPIMHEKK_01417 1.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPIMHEKK_01418 2e-172 ybbR S YbbR-like protein
KPIMHEKK_01419 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPIMHEKK_01420 7.3e-208 potD P ABC transporter
KPIMHEKK_01421 4.8e-127 potC P ABC transporter permease
KPIMHEKK_01422 1.3e-129 potB P ABC transporter permease
KPIMHEKK_01423 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KPIMHEKK_01424 2e-163 murB 1.3.1.98 M Cell wall formation
KPIMHEKK_01425 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
KPIMHEKK_01426 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KPIMHEKK_01427 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KPIMHEKK_01428 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPIMHEKK_01429 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
KPIMHEKK_01430 1.2e-94
KPIMHEKK_01431 3.8e-72 L Belongs to the 'phage' integrase family
KPIMHEKK_01433 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPIMHEKK_01434 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
KPIMHEKK_01435 1.6e-21
KPIMHEKK_01436 3.8e-77 comGF U Putative Competence protein ComGF
KPIMHEKK_01437 2.3e-41
KPIMHEKK_01438 1.8e-69
KPIMHEKK_01439 3.1e-43 comGC U competence protein ComGC
KPIMHEKK_01440 1.7e-171 comGB NU type II secretion system
KPIMHEKK_01441 1.7e-179 comGA NU Type II IV secretion system protein
KPIMHEKK_01442 8.9e-133 yebC K Transcriptional regulatory protein
KPIMHEKK_01443 7.6e-94 S VanZ like family
KPIMHEKK_01444 3.5e-101 ylbE GM NAD(P)H-binding
KPIMHEKK_01445 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPIMHEKK_01447 1.3e-160 L hmm pf00665
KPIMHEKK_01448 5.8e-100 L Helix-turn-helix domain
KPIMHEKK_01449 5.2e-20 E Amino acid permease
KPIMHEKK_01450 5.1e-248 E Amino acid permease
KPIMHEKK_01451 0.0 clpE O Belongs to the ClpA ClpB family
KPIMHEKK_01452 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
KPIMHEKK_01453 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KPIMHEKK_01454 1.4e-140 hlyX S Transporter associated domain
KPIMHEKK_01455 2.7e-74
KPIMHEKK_01456 1.6e-85
KPIMHEKK_01457 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
KPIMHEKK_01458 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPIMHEKK_01459 1.4e-118 D Alpha beta
KPIMHEKK_01460 1.8e-38 D Alpha beta
KPIMHEKK_01461 9.4e-46
KPIMHEKK_01462 7.7e-30 ropB K Helix-turn-helix domain
KPIMHEKK_01463 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KPIMHEKK_01464 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KPIMHEKK_01465 1.1e-71 yslB S Protein of unknown function (DUF2507)
KPIMHEKK_01466 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KPIMHEKK_01467 3.5e-54 trxA O Belongs to the thioredoxin family
KPIMHEKK_01468 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KPIMHEKK_01469 1.1e-50 yrzB S Belongs to the UPF0473 family
KPIMHEKK_01470 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPIMHEKK_01471 2e-42 yrzL S Belongs to the UPF0297 family
KPIMHEKK_01472 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPIMHEKK_01473 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KPIMHEKK_01474 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KPIMHEKK_01475 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPIMHEKK_01476 1.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KPIMHEKK_01477 9.6e-41 yajC U Preprotein translocase
KPIMHEKK_01478 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KPIMHEKK_01479 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KPIMHEKK_01480 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPIMHEKK_01481 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KPIMHEKK_01482 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KPIMHEKK_01483 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPIMHEKK_01484 3.5e-75
KPIMHEKK_01485 2.3e-181 M CHAP domain
KPIMHEKK_01486 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
KPIMHEKK_01487 3.7e-295 scrB 3.2.1.26 GH32 G invertase
KPIMHEKK_01488 1.1e-183 scrR K helix_turn _helix lactose operon repressor
KPIMHEKK_01489 1.8e-230 steT_1 E amino acid
KPIMHEKK_01490 2.2e-139 puuD S peptidase C26
KPIMHEKK_01492 2.4e-172 V HNH endonuclease
KPIMHEKK_01493 6.4e-135 S PFAM Archaeal ATPase
KPIMHEKK_01494 3.5e-247 yifK E Amino acid permease
KPIMHEKK_01495 9.7e-234 cycA E Amino acid permease
KPIMHEKK_01496 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KPIMHEKK_01497 0.0 clpE O AAA domain (Cdc48 subfamily)
KPIMHEKK_01498 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
KPIMHEKK_01499 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPIMHEKK_01500 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
KPIMHEKK_01501 0.0 XK27_06780 V ABC transporter permease
KPIMHEKK_01502 1.9e-36
KPIMHEKK_01503 7.9e-291 ytgP S Polysaccharide biosynthesis protein
KPIMHEKK_01504 2.7e-137 lysA2 M Glycosyl hydrolases family 25
KPIMHEKK_01505 2.3e-133 S Protein of unknown function (DUF975)
KPIMHEKK_01506 7.6e-177 pbpX2 V Beta-lactamase
KPIMHEKK_01507 6.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPIMHEKK_01508 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPIMHEKK_01509 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
KPIMHEKK_01510 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPIMHEKK_01511 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
KPIMHEKK_01512 4.1e-44
KPIMHEKK_01513 1e-207 ywhK S Membrane
KPIMHEKK_01514 1.5e-80 ykuL S (CBS) domain
KPIMHEKK_01515 0.0 cadA P P-type ATPase
KPIMHEKK_01516 2.8e-205 napA P Sodium/hydrogen exchanger family
KPIMHEKK_01517 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KPIMHEKK_01518 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
KPIMHEKK_01519 4.1e-276 V ABC transporter transmembrane region
KPIMHEKK_01520 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
KPIMHEKK_01521 5.4e-51
KPIMHEKK_01522 4.2e-154 EGP Major facilitator Superfamily
KPIMHEKK_01523 3e-111 ropB K Transcriptional regulator
KPIMHEKK_01524 2.7e-120 S CAAX protease self-immunity
KPIMHEKK_01525 1.6e-194 S DUF218 domain
KPIMHEKK_01526 0.0 macB_3 V ABC transporter, ATP-binding protein
KPIMHEKK_01527 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KPIMHEKK_01528 2.8e-100 S ECF transporter, substrate-specific component
KPIMHEKK_01529 4.7e-202 tcsA S ABC transporter substrate-binding protein PnrA-like
KPIMHEKK_01530 2.3e-176 tcsA S ABC transporter substrate-binding protein PnrA-like
KPIMHEKK_01531 3.7e-282 xylG 3.6.3.17 S ABC transporter
KPIMHEKK_01532 2.1e-197 yufP S Belongs to the binding-protein-dependent transport system permease family
KPIMHEKK_01533 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
KPIMHEKK_01534 2.4e-158 yeaE S Aldo/keto reductase family
KPIMHEKK_01535 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KPIMHEKK_01536 5.4e-101 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KPIMHEKK_01537 9.4e-72
KPIMHEKK_01538 8.2e-140 cof S haloacid dehalogenase-like hydrolase
KPIMHEKK_01539 8.2e-230 pbuG S permease
KPIMHEKK_01540 2.1e-76 S ABC-2 family transporter protein
KPIMHEKK_01541 4.7e-60 S ABC-2 family transporter protein
KPIMHEKK_01542 2.4e-92 V ABC transporter, ATP-binding protein
KPIMHEKK_01543 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
KPIMHEKK_01544 1.7e-113 tdk 2.7.1.21 F thymidine kinase
KPIMHEKK_01545 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPIMHEKK_01546 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KPIMHEKK_01547 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KPIMHEKK_01548 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KPIMHEKK_01549 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
KPIMHEKK_01550 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPIMHEKK_01551 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPIMHEKK_01552 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPIMHEKK_01553 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPIMHEKK_01554 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPIMHEKK_01555 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPIMHEKK_01556 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KPIMHEKK_01557 2e-30 ywzB S Protein of unknown function (DUF1146)
KPIMHEKK_01558 1.2e-177 mbl D Cell shape determining protein MreB Mrl
KPIMHEKK_01559 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KPIMHEKK_01560 3.3e-33 S Protein of unknown function (DUF2969)
KPIMHEKK_01561 4.7e-216 rodA D Belongs to the SEDS family
KPIMHEKK_01562 1.8e-78 usp6 T universal stress protein
KPIMHEKK_01563 8.4e-39
KPIMHEKK_01564 1.8e-145 rarA L recombination factor protein RarA
KPIMHEKK_01565 6e-55 rarA L recombination factor protein RarA
KPIMHEKK_01566 1.3e-84 yueI S Protein of unknown function (DUF1694)
KPIMHEKK_01567 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPIMHEKK_01568 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPIMHEKK_01569 6.2e-213 iscS2 2.8.1.7 E Aminotransferase class V
KPIMHEKK_01570 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPIMHEKK_01571 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KPIMHEKK_01572 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPIMHEKK_01573 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KPIMHEKK_01574 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
KPIMHEKK_01575 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KPIMHEKK_01576 1.5e-94 S Protein of unknown function (DUF3990)
KPIMHEKK_01577 6.5e-44
KPIMHEKK_01579 0.0 3.6.3.8 P P-type ATPase
KPIMHEKK_01580 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
KPIMHEKK_01581 2.5e-52
KPIMHEKK_01582 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KPIMHEKK_01583 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KPIMHEKK_01584 5.7e-126 S Haloacid dehalogenase-like hydrolase
KPIMHEKK_01585 2.3e-108 radC L DNA repair protein
KPIMHEKK_01586 2.4e-176 mreB D cell shape determining protein MreB
KPIMHEKK_01587 2e-147 mreC M Involved in formation and maintenance of cell shape
KPIMHEKK_01588 2.7e-94 mreD

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)