ORF_ID e_value Gene_name EC_number CAZy COGs Description
NHCLAHDE_00001 2.4e-91 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
NHCLAHDE_00002 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHCLAHDE_00003 3.5e-32 ykzG S Belongs to the UPF0356 family
NHCLAHDE_00004 2e-57 clcA P chloride
NHCLAHDE_00005 3.9e-113 L PFAM Integrase catalytic
NHCLAHDE_00006 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NHCLAHDE_00007 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NHCLAHDE_00008 6.4e-128 K UTRA domain
NHCLAHDE_00009 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHCLAHDE_00010 2e-85 alkD L DNA alkylation repair enzyme
NHCLAHDE_00011 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NHCLAHDE_00012 1.5e-81
NHCLAHDE_00013 3.6e-39 C FMN_bind
NHCLAHDE_00014 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
NHCLAHDE_00015 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
NHCLAHDE_00016 6e-151 3.1.3.48 T Tyrosine phosphatase family
NHCLAHDE_00017 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHCLAHDE_00019 3e-53 cvpA S Colicin V production protein
NHCLAHDE_00020 9.1e-66 L An automated process has identified a potential problem with this gene model
NHCLAHDE_00021 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NHCLAHDE_00022 5e-148 noc K Belongs to the ParB family
NHCLAHDE_00023 3.4e-138 soj D Sporulation initiation inhibitor
NHCLAHDE_00024 1.5e-153 spo0J K Belongs to the ParB family
NHCLAHDE_00025 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
NHCLAHDE_00026 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHCLAHDE_00027 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
NHCLAHDE_00028 1.2e-145 V ABC transporter, ATP-binding protein
NHCLAHDE_00029 4.2e-144 V ABC transporter, ATP-binding protein
NHCLAHDE_00030 0.0 V ABC transporter
NHCLAHDE_00032 9.6e-121 K response regulator
NHCLAHDE_00033 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
NHCLAHDE_00034 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHCLAHDE_00035 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NHCLAHDE_00036 1.4e-53 S Enterocin A Immunity
NHCLAHDE_00037 2.5e-33
NHCLAHDE_00038 9.5e-26
NHCLAHDE_00039 1e-24
NHCLAHDE_00040 1.1e-269 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NHCLAHDE_00041 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NHCLAHDE_00042 2.1e-255 S Archaea bacterial proteins of unknown function
NHCLAHDE_00043 1.2e-16
NHCLAHDE_00044 4.4e-138 2.7.13.3 T GHKL domain
NHCLAHDE_00045 1.2e-127 K LytTr DNA-binding domain
NHCLAHDE_00046 8.9e-268 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHCLAHDE_00047 8.8e-41 clcA P chloride
NHCLAHDE_00048 1.6e-60 clcA P chloride
NHCLAHDE_00049 4.7e-26 K FCD
NHCLAHDE_00050 1.8e-84 scrR K Periplasmic binding protein domain
NHCLAHDE_00051 2.1e-13 sprD D Domain of Unknown Function (DUF1542)
NHCLAHDE_00052 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHCLAHDE_00053 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NHCLAHDE_00054 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NHCLAHDE_00055 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NHCLAHDE_00056 3.4e-161 phnD P Phosphonate ABC transporter
NHCLAHDE_00058 8.8e-84 uspA T universal stress protein
NHCLAHDE_00059 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
NHCLAHDE_00060 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHCLAHDE_00061 3e-89 ntd 2.4.2.6 F Nucleoside
NHCLAHDE_00062 5.2e-08
NHCLAHDE_00063 4.4e-103 K Putative DNA-binding domain
NHCLAHDE_00064 9.3e-35
NHCLAHDE_00065 2e-157 S reductase
NHCLAHDE_00066 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
NHCLAHDE_00067 1.4e-126 pgm3 G Phosphoglycerate mutase family
NHCLAHDE_00068 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NHCLAHDE_00069 0.0 helD 3.6.4.12 L DNA helicase
NHCLAHDE_00070 1.5e-107 glnP P ABC transporter permease
NHCLAHDE_00071 1e-105 glnQ 3.6.3.21 E ABC transporter
NHCLAHDE_00072 1.6e-143 aatB ET ABC transporter substrate-binding protein
NHCLAHDE_00073 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
NHCLAHDE_00074 7.1e-98 E GDSL-like Lipase/Acylhydrolase
NHCLAHDE_00075 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
NHCLAHDE_00076 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHCLAHDE_00077 8.8e-58 S Peptidase propeptide and YPEB domain
NHCLAHDE_00078 1.3e-30
NHCLAHDE_00079 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
NHCLAHDE_00080 3.7e-102 L Integrase
NHCLAHDE_00081 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
NHCLAHDE_00082 4.1e-36 ptp2 3.1.3.48 T Tyrosine phosphatase family
NHCLAHDE_00083 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NHCLAHDE_00084 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
NHCLAHDE_00085 1.4e-36 S Cytochrome B5
NHCLAHDE_00086 6e-168 arbZ I Phosphate acyltransferases
NHCLAHDE_00087 1.6e-182 arbY M Glycosyl transferase family 8
NHCLAHDE_00088 5e-184 arbY M Glycosyl transferase family 8
NHCLAHDE_00089 5e-156 arbx M Glycosyl transferase family 8
NHCLAHDE_00090 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
NHCLAHDE_00092 4.9e-34
NHCLAHDE_00094 4.8e-131 K response regulator
NHCLAHDE_00095 2.2e-305 vicK 2.7.13.3 T Histidine kinase
NHCLAHDE_00096 1.6e-257 yycH S YycH protein
NHCLAHDE_00097 3.4e-149 yycI S YycH protein
NHCLAHDE_00098 4.1e-147 vicX 3.1.26.11 S domain protein
NHCLAHDE_00099 1.6e-161 htrA 3.4.21.107 O serine protease
NHCLAHDE_00100 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHCLAHDE_00101 4e-08
NHCLAHDE_00102 6.6e-56
NHCLAHDE_00103 2.7e-57
NHCLAHDE_00104 1.6e-11
NHCLAHDE_00105 8.1e-126 S PAS domain
NHCLAHDE_00106 2.6e-106 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NHCLAHDE_00107 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NHCLAHDE_00108 1.1e-133 S membrane transporter protein
NHCLAHDE_00109 2.2e-125 gpmB G Belongs to the phosphoglycerate mutase family
NHCLAHDE_00110 6.6e-162 czcD P cation diffusion facilitator family transporter
NHCLAHDE_00111 1.4e-23
NHCLAHDE_00112 1.7e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHCLAHDE_00113 2.4e-183 S AAA domain
NHCLAHDE_00114 8.1e-43
NHCLAHDE_00115 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
NHCLAHDE_00116 4.1e-52
NHCLAHDE_00117 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NHCLAHDE_00118 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHCLAHDE_00119 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHCLAHDE_00120 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHCLAHDE_00121 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHCLAHDE_00122 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHCLAHDE_00123 1.2e-94 sigH K Belongs to the sigma-70 factor family
NHCLAHDE_00124 1.7e-34
NHCLAHDE_00125 1.4e-118 D Alpha beta
NHCLAHDE_00126 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHCLAHDE_00127 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
NHCLAHDE_00128 1.6e-85
NHCLAHDE_00129 2.7e-74
NHCLAHDE_00130 1.4e-140 hlyX S Transporter associated domain
NHCLAHDE_00131 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHCLAHDE_00132 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
NHCLAHDE_00133 0.0 clpE O Belongs to the ClpA ClpB family
NHCLAHDE_00134 7.5e-231 pbuG S permease
NHCLAHDE_00135 2.5e-119 K helix_turn_helix, mercury resistance
NHCLAHDE_00136 3.3e-37
NHCLAHDE_00137 8.2e-288 P ABC transporter
NHCLAHDE_00138 4.3e-36
NHCLAHDE_00140 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NHCLAHDE_00141 2.5e-86 K GNAT family
NHCLAHDE_00142 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
NHCLAHDE_00143 2.9e-122 rbtT P Major Facilitator Superfamily
NHCLAHDE_00144 4.2e-63 lmrB EGP Major facilitator Superfamily
NHCLAHDE_00145 5.8e-78 M LysM domain protein
NHCLAHDE_00146 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHCLAHDE_00147 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHCLAHDE_00148 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHCLAHDE_00149 6.2e-12
NHCLAHDE_00150 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NHCLAHDE_00151 2.3e-30
NHCLAHDE_00153 2.9e-69 S Iron-sulphur cluster biosynthesis
NHCLAHDE_00154 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
NHCLAHDE_00155 6.2e-59 psiE S Phosphate-starvation-inducible E
NHCLAHDE_00157 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NHCLAHDE_00158 4.3e-228 amtB P ammonium transporter
NHCLAHDE_00159 1.4e-60
NHCLAHDE_00160 0.0 lhr L DEAD DEAH box helicase
NHCLAHDE_00161 1.4e-245 P P-loop Domain of unknown function (DUF2791)
NHCLAHDE_00162 2.6e-138 S TerB-C domain
NHCLAHDE_00163 1.1e-56 S Protein of unknown function (DUF3290)
NHCLAHDE_00164 3e-116 yviA S Protein of unknown function (DUF421)
NHCLAHDE_00165 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NHCLAHDE_00166 8e-182 dnaQ 2.7.7.7 L EXOIII
NHCLAHDE_00167 1.9e-158 endA F DNA RNA non-specific endonuclease
NHCLAHDE_00168 1.3e-281 pipD E Dipeptidase
NHCLAHDE_00169 1.9e-203 malK P ATPases associated with a variety of cellular activities
NHCLAHDE_00170 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
NHCLAHDE_00171 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
NHCLAHDE_00172 1e-256 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
NHCLAHDE_00173 2.3e-240 G Bacterial extracellular solute-binding protein
NHCLAHDE_00174 1.8e-154 corA P CorA-like Mg2+ transporter protein
NHCLAHDE_00175 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
NHCLAHDE_00176 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
NHCLAHDE_00177 0.0 ydgH S MMPL family
NHCLAHDE_00179 7.8e-26 K Acetyltransferase (GNAT) domain
NHCLAHDE_00180 1.8e-163
NHCLAHDE_00181 4.4e-239 L transposase, IS605 OrfB family
NHCLAHDE_00182 2.1e-28 S Peptidase propeptide and YPEB domain
NHCLAHDE_00183 2.4e-60 ypaA S Protein of unknown function (DUF1304)
NHCLAHDE_00184 2.3e-309 oppA3 E ABC transporter, substratebinding protein
NHCLAHDE_00185 9e-161 V ABC transporter transmembrane region
NHCLAHDE_00186 7e-68 V ABC transporter transmembrane region
NHCLAHDE_00187 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
NHCLAHDE_00188 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NHCLAHDE_00189 2.5e-72 S Peptidase propeptide and YPEB domain
NHCLAHDE_00190 3.4e-76 S Peptidase propeptide and YPEB domain
NHCLAHDE_00191 5.2e-187 T GHKL domain
NHCLAHDE_00192 3.1e-130 T Transcriptional regulatory protein, C terminal
NHCLAHDE_00193 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NHCLAHDE_00194 2.9e-277 V ABC transporter transmembrane region
NHCLAHDE_00195 1.6e-15 L hmm pf00665
NHCLAHDE_00196 2.9e-15 M LysM domain protein
NHCLAHDE_00197 3.8e-48 M LysM domain protein
NHCLAHDE_00198 1.9e-86 C Aldo keto reductase
NHCLAHDE_00199 8.3e-181 lacX 5.1.3.3 G Aldose 1-epimerase
NHCLAHDE_00200 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NHCLAHDE_00201 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NHCLAHDE_00202 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
NHCLAHDE_00203 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHCLAHDE_00204 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHCLAHDE_00205 5.8e-152 dprA LU DNA protecting protein DprA
NHCLAHDE_00206 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHCLAHDE_00207 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHCLAHDE_00208 1.9e-94 yjcE P Sodium proton antiporter
NHCLAHDE_00209 1.5e-40 yjcE P Sodium proton antiporter
NHCLAHDE_00210 1.1e-66 yjcE P NhaP-type Na H and K H
NHCLAHDE_00211 7.1e-36 yozE S Belongs to the UPF0346 family
NHCLAHDE_00212 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
NHCLAHDE_00213 1.2e-107 hlyIII S protein, hemolysin III
NHCLAHDE_00214 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHCLAHDE_00215 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHCLAHDE_00216 1.6e-85 3.4.21.96 S SLAP domain
NHCLAHDE_00217 8.4e-128 yagE E Amino acid permease
NHCLAHDE_00218 9.7e-65 yagE E amino acid
NHCLAHDE_00219 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NHCLAHDE_00220 2.6e-115 dedA S SNARE-like domain protein
NHCLAHDE_00221 3.7e-100 S Protein of unknown function (DUF1461)
NHCLAHDE_00222 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHCLAHDE_00223 2.6e-92 yutD S Protein of unknown function (DUF1027)
NHCLAHDE_00224 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NHCLAHDE_00225 4.3e-55
NHCLAHDE_00226 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHCLAHDE_00227 1.2e-180 ccpA K catabolite control protein A
NHCLAHDE_00228 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NHCLAHDE_00229 1.3e-36
NHCLAHDE_00230 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHCLAHDE_00231 3.7e-146 ykuT M mechanosensitive ion channel
NHCLAHDE_00232 6.9e-100 V ATPases associated with a variety of cellular activities
NHCLAHDE_00233 1.7e-139
NHCLAHDE_00234 5.4e-113
NHCLAHDE_00235 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHCLAHDE_00236 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHCLAHDE_00237 1.7e-29 secG U Preprotein translocase
NHCLAHDE_00238 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHCLAHDE_00239 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHCLAHDE_00240 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
NHCLAHDE_00241 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NHCLAHDE_00269 8e-225 pbuG S permease
NHCLAHDE_00270 9.7e-146 S haloacid dehalogenase-like hydrolase
NHCLAHDE_00271 2e-225 S cog cog1373
NHCLAHDE_00272 6.1e-61 K Transcriptional regulator
NHCLAHDE_00273 1.3e-94 K Transcriptional regulator
NHCLAHDE_00274 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NHCLAHDE_00275 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHCLAHDE_00276 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
NHCLAHDE_00277 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHCLAHDE_00278 2.4e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHCLAHDE_00279 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHCLAHDE_00280 5.1e-198 oppD P Belongs to the ABC transporter superfamily
NHCLAHDE_00281 1.9e-175 oppF P Belongs to the ABC transporter superfamily
NHCLAHDE_00282 5.2e-256 pepC 3.4.22.40 E aminopeptidase
NHCLAHDE_00283 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
NHCLAHDE_00284 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHCLAHDE_00285 7.9e-112
NHCLAHDE_00287 1.2e-111 E Belongs to the SOS response-associated peptidase family
NHCLAHDE_00288 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHCLAHDE_00289 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
NHCLAHDE_00290 2e-103 S TPM domain
NHCLAHDE_00291 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NHCLAHDE_00292 1.3e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NHCLAHDE_00293 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHCLAHDE_00294 1e-147 tatD L hydrolase, TatD family
NHCLAHDE_00295 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHCLAHDE_00296 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHCLAHDE_00297 4.5e-39 veg S Biofilm formation stimulator VEG
NHCLAHDE_00298 3.2e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NHCLAHDE_00299 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHCLAHDE_00300 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NHCLAHDE_00301 1.8e-104 3.2.2.20 K acetyltransferase
NHCLAHDE_00303 4.3e-226 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHCLAHDE_00304 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
NHCLAHDE_00305 4.1e-21 K Helix-turn-helix domain, rpiR family
NHCLAHDE_00306 2e-72 K Helix-turn-helix domain, rpiR family
NHCLAHDE_00307 3.2e-101 3.6.1.27 I Acid phosphatase homologues
NHCLAHDE_00308 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
NHCLAHDE_00309 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHCLAHDE_00310 6.3e-33 S Domain of unknown function (DUF4767)
NHCLAHDE_00311 5e-85 S PFAM Archaeal ATPase
NHCLAHDE_00312 5.7e-84 S PFAM Archaeal ATPase
NHCLAHDE_00313 7.7e-26
NHCLAHDE_00314 3.1e-71 2.5.1.74 H UbiA prenyltransferase family
NHCLAHDE_00315 3e-24
NHCLAHDE_00316 1.5e-152
NHCLAHDE_00317 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHCLAHDE_00318 0.0 typA T GTP-binding protein TypA
NHCLAHDE_00319 5.9e-211 ftsW D Belongs to the SEDS family
NHCLAHDE_00320 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NHCLAHDE_00321 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NHCLAHDE_00322 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHCLAHDE_00323 2.4e-187 ylbL T Belongs to the peptidase S16 family
NHCLAHDE_00324 3.1e-79 comEA L Competence protein ComEA
NHCLAHDE_00325 0.0 comEC S Competence protein ComEC
NHCLAHDE_00326 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
NHCLAHDE_00327 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
NHCLAHDE_00328 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHCLAHDE_00329 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHCLAHDE_00330 1.3e-148
NHCLAHDE_00331 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHCLAHDE_00332 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHCLAHDE_00333 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHCLAHDE_00334 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
NHCLAHDE_00335 7.8e-39 yjeM E Amino Acid
NHCLAHDE_00336 3.4e-209 yjeM E Amino Acid
NHCLAHDE_00337 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHCLAHDE_00338 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHCLAHDE_00339 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHCLAHDE_00340 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHCLAHDE_00341 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHCLAHDE_00342 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHCLAHDE_00343 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHCLAHDE_00344 2.7e-216 aspC 2.6.1.1 E Aminotransferase
NHCLAHDE_00345 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHCLAHDE_00346 2.2e-135 pbpX1 V Beta-lactamase
NHCLAHDE_00347 1.2e-299 I Protein of unknown function (DUF2974)
NHCLAHDE_00348 1.3e-260 emrY EGP Major facilitator Superfamily
NHCLAHDE_00349 1.1e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHCLAHDE_00350 7.6e-239 pyrP F Permease
NHCLAHDE_00351 1.9e-22 K Putative DNA-binding domain
NHCLAHDE_00352 8.3e-24 papP P ABC transporter, permease protein
NHCLAHDE_00354 4.5e-58 yodB K Transcriptional regulator, HxlR family
NHCLAHDE_00355 2.2e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHCLAHDE_00356 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NHCLAHDE_00357 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHCLAHDE_00358 6.3e-82 S Aminoacyl-tRNA editing domain
NHCLAHDE_00359 6.1e-224 S SLAP domain
NHCLAHDE_00360 1.5e-97 S CAAX protease self-immunity
NHCLAHDE_00361 1e-12
NHCLAHDE_00362 1.3e-277 arlS 2.7.13.3 T Histidine kinase
NHCLAHDE_00363 1.2e-126 K response regulator
NHCLAHDE_00364 4.7e-97 yceD S Uncharacterized ACR, COG1399
NHCLAHDE_00365 4.6e-216 ylbM S Belongs to the UPF0348 family
NHCLAHDE_00366 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHCLAHDE_00367 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NHCLAHDE_00368 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHCLAHDE_00369 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
NHCLAHDE_00370 4.2e-84 yqeG S HAD phosphatase, family IIIA
NHCLAHDE_00371 4.3e-198 tnpB L Putative transposase DNA-binding domain
NHCLAHDE_00372 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHCLAHDE_00373 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHCLAHDE_00374 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NHCLAHDE_00375 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHCLAHDE_00376 2.7e-36 yyaR K Acetyltransferase (GNAT) domain
NHCLAHDE_00377 1.1e-75 V ABC transporter transmembrane region
NHCLAHDE_00378 1.4e-223 L transposase, IS605 OrfB family
NHCLAHDE_00379 6.1e-136 V ABC transporter transmembrane region
NHCLAHDE_00380 1.7e-184 G Transmembrane secretion effector
NHCLAHDE_00381 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NHCLAHDE_00382 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHCLAHDE_00383 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
NHCLAHDE_00384 0.0 pepF E oligoendopeptidase F
NHCLAHDE_00385 2.9e-31
NHCLAHDE_00386 1.3e-69 doc S Prophage maintenance system killer protein
NHCLAHDE_00389 4.6e-27 S Enterocin A Immunity
NHCLAHDE_00390 1.7e-22 blpT
NHCLAHDE_00391 2.3e-187 K Periplasmic binding protein-like domain
NHCLAHDE_00392 2e-106 K Transcriptional regulator, AbiEi antitoxin
NHCLAHDE_00393 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NHCLAHDE_00394 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHCLAHDE_00395 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NHCLAHDE_00396 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NHCLAHDE_00397 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NHCLAHDE_00398 2.1e-164 lacR K Transcriptional regulator
NHCLAHDE_00399 1.1e-137 lacS G Transporter
NHCLAHDE_00400 8.7e-57 lacS G Transporter
NHCLAHDE_00401 2.6e-103 lacS G Transporter
NHCLAHDE_00402 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NHCLAHDE_00403 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHCLAHDE_00404 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NHCLAHDE_00405 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NHCLAHDE_00406 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
NHCLAHDE_00407 1.3e-282 xylG 3.6.3.17 S ABC transporter
NHCLAHDE_00408 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
NHCLAHDE_00409 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
NHCLAHDE_00410 1.1e-158 yeaE S Aldo/keto reductase family
NHCLAHDE_00411 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHCLAHDE_00412 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NHCLAHDE_00413 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NHCLAHDE_00414 9.4e-72
NHCLAHDE_00415 8.2e-140 cof S haloacid dehalogenase-like hydrolase
NHCLAHDE_00416 8.2e-230 pbuG S permease
NHCLAHDE_00417 2.1e-76 S ABC-2 family transporter protein
NHCLAHDE_00418 1.8e-21 S ABC-2 family transporter protein
NHCLAHDE_00419 7.6e-31 S ABC-2 family transporter protein
NHCLAHDE_00420 1.4e-72 V ABC transporter, ATP-binding protein
NHCLAHDE_00421 1.2e-222 patA 2.6.1.1 E Aminotransferase
NHCLAHDE_00422 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHCLAHDE_00423 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NHCLAHDE_00424 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHCLAHDE_00425 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHCLAHDE_00426 8.5e-60
NHCLAHDE_00427 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
NHCLAHDE_00428 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHCLAHDE_00429 5.9e-37 M domain protein
NHCLAHDE_00431 6.9e-248 yjjP S Putative threonine/serine exporter
NHCLAHDE_00432 2.6e-177 citR K Putative sugar-binding domain
NHCLAHDE_00433 1.5e-50
NHCLAHDE_00434 5.5e-09
NHCLAHDE_00435 2.9e-66 S Domain of unknown function DUF1828
NHCLAHDE_00436 1.5e-95 S UPF0397 protein
NHCLAHDE_00437 0.0 ykoD P ABC transporter, ATP-binding protein
NHCLAHDE_00438 3.6e-146 cbiQ P cobalt transport
NHCLAHDE_00439 3.5e-21
NHCLAHDE_00440 9.3e-72 yeaL S Protein of unknown function (DUF441)
NHCLAHDE_00441 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NHCLAHDE_00442 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NHCLAHDE_00443 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
NHCLAHDE_00444 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NHCLAHDE_00445 1.7e-153 ydjP I Alpha/beta hydrolase family
NHCLAHDE_00446 2.2e-179 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHCLAHDE_00447 2.6e-280 thrC 4.2.3.1 E Threonine synthase
NHCLAHDE_00448 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NHCLAHDE_00449 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHCLAHDE_00450 9.4e-118
NHCLAHDE_00451 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHCLAHDE_00453 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHCLAHDE_00454 1.3e-116 S Peptidase family M23
NHCLAHDE_00455 1.2e-79 K Acetyltransferase (GNAT) domain
NHCLAHDE_00456 2.7e-155 M Belongs to the glycosyl hydrolase 28 family
NHCLAHDE_00457 1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
NHCLAHDE_00458 6.5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHCLAHDE_00459 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHCLAHDE_00460 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHCLAHDE_00461 3.5e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHCLAHDE_00462 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHCLAHDE_00463 1.4e-60 rplQ J Ribosomal protein L17
NHCLAHDE_00464 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHCLAHDE_00465 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHCLAHDE_00466 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHCLAHDE_00467 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NHCLAHDE_00468 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHCLAHDE_00469 1e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHCLAHDE_00470 9e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHCLAHDE_00471 2.6e-71 rplO J Binds to the 23S rRNA
NHCLAHDE_00472 2.3e-24 rpmD J Ribosomal protein L30
NHCLAHDE_00473 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHCLAHDE_00474 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHCLAHDE_00475 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHCLAHDE_00476 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHCLAHDE_00477 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHCLAHDE_00478 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHCLAHDE_00479 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHCLAHDE_00480 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHCLAHDE_00481 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHCLAHDE_00482 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NHCLAHDE_00483 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHCLAHDE_00484 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHCLAHDE_00485 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHCLAHDE_00486 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHCLAHDE_00487 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHCLAHDE_00488 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHCLAHDE_00489 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
NHCLAHDE_00490 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHCLAHDE_00491 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NHCLAHDE_00492 1.5e-80
NHCLAHDE_00493 1.6e-73 marR K Transcriptional regulator, MarR family
NHCLAHDE_00494 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NHCLAHDE_00495 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHCLAHDE_00496 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHCLAHDE_00497 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHCLAHDE_00498 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NHCLAHDE_00499 2.9e-107 IQ reductase
NHCLAHDE_00500 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHCLAHDE_00501 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHCLAHDE_00502 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NHCLAHDE_00503 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NHCLAHDE_00504 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHCLAHDE_00505 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NHCLAHDE_00506 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NHCLAHDE_00507 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHCLAHDE_00508 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHCLAHDE_00511 3.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
NHCLAHDE_00512 1.3e-273 E amino acid
NHCLAHDE_00513 5.2e-26 L Helicase C-terminal domain protein
NHCLAHDE_00514 0.0 L Helicase C-terminal domain protein
NHCLAHDE_00515 4.8e-205 pbpX1 V Beta-lactamase
NHCLAHDE_00516 5.1e-226 N Uncharacterized conserved protein (DUF2075)
NHCLAHDE_00517 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHCLAHDE_00518 1.3e-38 S RelB antitoxin
NHCLAHDE_00519 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NHCLAHDE_00520 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHCLAHDE_00521 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
NHCLAHDE_00522 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHCLAHDE_00523 8.7e-159 isdE P Periplasmic binding protein
NHCLAHDE_00524 6.3e-123 M Iron Transport-associated domain
NHCLAHDE_00525 3e-09 isdH M Iron Transport-associated domain
NHCLAHDE_00526 8.4e-89
NHCLAHDE_00527 6.4e-113 S SLAP domain
NHCLAHDE_00528 1.2e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHCLAHDE_00529 2.4e-10 L Psort location Cytoplasmic, score
NHCLAHDE_00530 7.4e-97 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHCLAHDE_00531 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHCLAHDE_00532 1.8e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NHCLAHDE_00533 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NHCLAHDE_00534 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHCLAHDE_00535 6.3e-120 lsa S ABC transporter
NHCLAHDE_00536 3.3e-106 S domain protein
NHCLAHDE_00537 4.3e-140 V ABC transporter
NHCLAHDE_00538 5.9e-68 S Protein of unknown function (DUF3021)
NHCLAHDE_00539 6e-86
NHCLAHDE_00540 4.4e-172 S Domain of unknown function (DUF389)
NHCLAHDE_00541 9.1e-54 papP P ABC transporter, permease protein
NHCLAHDE_00542 5.3e-116 P ABC transporter permease
NHCLAHDE_00543 1.5e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHCLAHDE_00544 1e-156 cjaA ET ABC transporter substrate-binding protein
NHCLAHDE_00545 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHCLAHDE_00546 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHCLAHDE_00547 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHCLAHDE_00548 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
NHCLAHDE_00549 7.1e-158 metQ1 P Belongs to the nlpA lipoprotein family
NHCLAHDE_00550 1.9e-25
NHCLAHDE_00551 0.0 mco Q Multicopper oxidase
NHCLAHDE_00552 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
NHCLAHDE_00553 0.0 oppA E ABC transporter
NHCLAHDE_00554 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
NHCLAHDE_00555 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
NHCLAHDE_00556 1e-137 S Protein of unknown function (DUF3100)
NHCLAHDE_00557 9.7e-83 S An automated process has identified a potential problem with this gene model
NHCLAHDE_00558 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NHCLAHDE_00559 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHCLAHDE_00560 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHCLAHDE_00561 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
NHCLAHDE_00562 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHCLAHDE_00563 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHCLAHDE_00564 2.8e-157 pstS P Phosphate
NHCLAHDE_00565 2.6e-162 pstC P probably responsible for the translocation of the substrate across the membrane
NHCLAHDE_00566 9.1e-66 L An automated process has identified a potential problem with this gene model
NHCLAHDE_00567 2e-35
NHCLAHDE_00569 2.5e-103 pncA Q Isochorismatase family
NHCLAHDE_00570 4.9e-118
NHCLAHDE_00573 6.6e-40
NHCLAHDE_00574 4.4e-151 S Metal-independent alpha-mannosidase (GH125)
NHCLAHDE_00576 3.3e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHCLAHDE_00577 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHCLAHDE_00578 3.5e-70 S Domain of unknown function (DUF3284)
NHCLAHDE_00579 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHCLAHDE_00580 3.7e-131 gmuR K UTRA
NHCLAHDE_00581 1.3e-159 degV S EDD domain protein, DegV family
NHCLAHDE_00582 1.1e-66
NHCLAHDE_00583 0.0 FbpA K Fibronectin-binding protein
NHCLAHDE_00584 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NHCLAHDE_00585 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHCLAHDE_00586 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHCLAHDE_00587 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHCLAHDE_00588 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NHCLAHDE_00589 5.5e-53
NHCLAHDE_00591 2.7e-34 S YSIRK type signal peptide
NHCLAHDE_00592 1.9e-110 F DNA/RNA non-specific endonuclease
NHCLAHDE_00593 3.4e-75 S cog cog0433
NHCLAHDE_00594 1.1e-282 phoR 2.7.13.3 T Histidine kinase
NHCLAHDE_00595 9.5e-121 T Transcriptional regulatory protein, C terminal
NHCLAHDE_00596 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
NHCLAHDE_00597 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHCLAHDE_00598 1.2e-152 pstA P Phosphate transport system permease protein PstA
NHCLAHDE_00599 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NHCLAHDE_00600 4.2e-145 pstS P Phosphate
NHCLAHDE_00601 1.3e-30
NHCLAHDE_00602 1.4e-191 oppA E ABC transporter, substratebinding protein
NHCLAHDE_00603 4.7e-275 ytgP S Polysaccharide biosynthesis protein
NHCLAHDE_00604 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHCLAHDE_00605 1.1e-121 3.6.1.27 I Acid phosphatase homologues
NHCLAHDE_00606 2.8e-168 K LysR substrate binding domain
NHCLAHDE_00607 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHCLAHDE_00608 6.2e-43 1.3.5.4 C FAD binding domain
NHCLAHDE_00609 1.1e-231 ndh 1.6.99.3 C NADH dehydrogenase
NHCLAHDE_00610 7.3e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NHCLAHDE_00611 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHCLAHDE_00612 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHCLAHDE_00613 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NHCLAHDE_00614 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NHCLAHDE_00615 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NHCLAHDE_00616 2.8e-221 cydA 1.10.3.14 C ubiquinol oxidase
NHCLAHDE_00617 2.2e-31 cydA 1.10.3.14 C ubiquinol oxidase
NHCLAHDE_00618 3.7e-130 ybbH_2 K rpiR family
NHCLAHDE_00619 3.4e-195 S Bacterial protein of unknown function (DUF871)
NHCLAHDE_00620 4.4e-48 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHCLAHDE_00621 1.6e-157 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHCLAHDE_00622 1.8e-119 S Putative esterase
NHCLAHDE_00623 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NHCLAHDE_00624 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
NHCLAHDE_00626 8.5e-260 qacA EGP Major facilitator Superfamily
NHCLAHDE_00627 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHCLAHDE_00630 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
NHCLAHDE_00632 1.6e-310 oppA E ABC transporter, substratebinding protein
NHCLAHDE_00633 5e-301 oppA E ABC transporter, substratebinding protein
NHCLAHDE_00634 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHCLAHDE_00635 4.6e-257 pepC 3.4.22.40 E aminopeptidase
NHCLAHDE_00637 3.4e-53
NHCLAHDE_00638 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHCLAHDE_00639 8.4e-265 S Fibronectin type III domain
NHCLAHDE_00640 2.6e-61 M Glycosyl hydrolases family 25
NHCLAHDE_00641 1.3e-61 M Glycosyl hydrolases family 25
NHCLAHDE_00642 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
NHCLAHDE_00643 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHCLAHDE_00645 4.5e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHCLAHDE_00646 2e-42 fryA 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHCLAHDE_00647 5.3e-37 mngA 2.7.1.195, 2.7.1.202 G Psort location Cytoplasmic, score 9.98
NHCLAHDE_00648 1.4e-150 mngA 2.7.1.195, 2.7.1.202 U system, fructose-specific IIC component
NHCLAHDE_00649 5.5e-281 ybgG 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
NHCLAHDE_00650 1.4e-137 licR 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
NHCLAHDE_00651 0.0 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
NHCLAHDE_00652 5.9e-45
NHCLAHDE_00653 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHCLAHDE_00655 2.1e-45 S PFAM Archaeal ATPase
NHCLAHDE_00656 7.3e-74
NHCLAHDE_00657 0.0 kup P Transport of potassium into the cell
NHCLAHDE_00658 0.0 pepO 3.4.24.71 O Peptidase family M13
NHCLAHDE_00659 1.4e-210 yttB EGP Major facilitator Superfamily
NHCLAHDE_00660 1.5e-230 XK27_04775 S PAS domain
NHCLAHDE_00661 6.2e-103 S Iron-sulfur cluster assembly protein
NHCLAHDE_00662 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHCLAHDE_00663 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NHCLAHDE_00664 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
NHCLAHDE_00665 0.0 asnB 6.3.5.4 E Asparagine synthase
NHCLAHDE_00666 1.3e-270 S Calcineurin-like phosphoesterase
NHCLAHDE_00667 3.9e-84
NHCLAHDE_00668 1.6e-105 tag 3.2.2.20 L glycosylase
NHCLAHDE_00669 4.5e-168 L COG3385 FOG Transposase and inactivated derivatives
NHCLAHDE_00670 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NHCLAHDE_00671 1.6e-294 L Nuclease-related domain
NHCLAHDE_00672 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHCLAHDE_00673 8.3e-106 S Repeat protein
NHCLAHDE_00674 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NHCLAHDE_00675 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHCLAHDE_00676 5.4e-56 XK27_04120 S Putative amino acid metabolism
NHCLAHDE_00677 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
NHCLAHDE_00678 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHCLAHDE_00679 6.7e-37
NHCLAHDE_00680 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NHCLAHDE_00681 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
NHCLAHDE_00682 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHCLAHDE_00683 2.8e-74 gpsB D DivIVA domain protein
NHCLAHDE_00684 5.7e-149 ylmH S S4 domain protein
NHCLAHDE_00685 1.7e-45 yggT S YGGT family
NHCLAHDE_00686 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHCLAHDE_00687 5e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHCLAHDE_00688 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHCLAHDE_00689 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHCLAHDE_00690 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHCLAHDE_00691 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHCLAHDE_00692 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHCLAHDE_00693 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NHCLAHDE_00694 1.8e-54 ftsL D Cell division protein FtsL
NHCLAHDE_00695 2.1e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHCLAHDE_00696 6.3e-78 mraZ K Belongs to the MraZ family
NHCLAHDE_00697 6.4e-54 S Protein of unknown function (DUF3397)
NHCLAHDE_00699 2.7e-94 mreD
NHCLAHDE_00700 2e-147 mreC M Involved in formation and maintenance of cell shape
NHCLAHDE_00701 2.4e-176 mreB D cell shape determining protein MreB
NHCLAHDE_00702 2.3e-108 radC L DNA repair protein
NHCLAHDE_00703 5.7e-126 S Haloacid dehalogenase-like hydrolase
NHCLAHDE_00704 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHCLAHDE_00705 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHCLAHDE_00706 2.5e-52
NHCLAHDE_00707 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
NHCLAHDE_00708 0.0 3.6.3.8 P P-type ATPase
NHCLAHDE_00710 6.5e-44
NHCLAHDE_00711 1.5e-94 S Protein of unknown function (DUF3990)
NHCLAHDE_00712 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NHCLAHDE_00713 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
NHCLAHDE_00714 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHCLAHDE_00715 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHCLAHDE_00716 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NHCLAHDE_00717 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHCLAHDE_00718 7.4e-214 iscS2 2.8.1.7 E Aminotransferase class V
NHCLAHDE_00719 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHCLAHDE_00720 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHCLAHDE_00721 1.3e-84 yueI S Protein of unknown function (DUF1694)
NHCLAHDE_00722 2.2e-238 rarA L recombination factor protein RarA
NHCLAHDE_00723 8.4e-39
NHCLAHDE_00724 1.8e-78 usp6 T universal stress protein
NHCLAHDE_00725 4.7e-216 rodA D Belongs to the SEDS family
NHCLAHDE_00726 3.3e-33 S Protein of unknown function (DUF2969)
NHCLAHDE_00727 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NHCLAHDE_00728 4.7e-177 mbl D Cell shape determining protein MreB Mrl
NHCLAHDE_00729 2e-30 ywzB S Protein of unknown function (DUF1146)
NHCLAHDE_00730 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NHCLAHDE_00731 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHCLAHDE_00732 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHCLAHDE_00733 2.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHCLAHDE_00734 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHCLAHDE_00735 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHCLAHDE_00736 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHCLAHDE_00737 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
NHCLAHDE_00738 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHCLAHDE_00739 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHCLAHDE_00740 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHCLAHDE_00741 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHCLAHDE_00742 1.3e-113 tdk 2.7.1.21 F thymidine kinase
NHCLAHDE_00743 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NHCLAHDE_00746 3.9e-195 ampC V Beta-lactamase
NHCLAHDE_00747 3.8e-217 EGP Major facilitator Superfamily
NHCLAHDE_00748 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
NHCLAHDE_00749 3.8e-105 vanZ V VanZ like family
NHCLAHDE_00750 1.9e-286 clcA P chloride
NHCLAHDE_00751 4e-32 E Zn peptidase
NHCLAHDE_00752 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
NHCLAHDE_00753 1.2e-44
NHCLAHDE_00754 9.1e-106 S Bacteriocin helveticin-J
NHCLAHDE_00755 5.7e-62 S SLAP domain
NHCLAHDE_00756 1e-95
NHCLAHDE_00757 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
NHCLAHDE_00759 4.5e-185 3.2.1.18 GH33 M Rib/alpha-like repeat
NHCLAHDE_00760 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
NHCLAHDE_00761 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NHCLAHDE_00763 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NHCLAHDE_00764 2.4e-43 K Helix-turn-helix
NHCLAHDE_00765 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHCLAHDE_00766 1.4e-226 pbuX F xanthine permease
NHCLAHDE_00767 2.5e-152 msmR K AraC-like ligand binding domain
NHCLAHDE_00768 4.4e-285 pipD E Dipeptidase
NHCLAHDE_00769 1.3e-47 adk 2.7.4.3 F AAA domain
NHCLAHDE_00770 2.1e-80 K acetyltransferase
NHCLAHDE_00771 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHCLAHDE_00772 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHCLAHDE_00773 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHCLAHDE_00774 4.5e-68 S Domain of unknown function (DUF1934)
NHCLAHDE_00775 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHCLAHDE_00776 3.7e-19 S Alpha beta hydrolase
NHCLAHDE_00777 1.2e-63 S Alpha beta hydrolase
NHCLAHDE_00778 1.9e-37
NHCLAHDE_00779 7e-50
NHCLAHDE_00780 1.7e-148 S haloacid dehalogenase-like hydrolase
NHCLAHDE_00781 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
NHCLAHDE_00782 8.3e-277 V ABC-type multidrug transport system, ATPase and permease components
NHCLAHDE_00783 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
NHCLAHDE_00784 8.5e-178 I Carboxylesterase family
NHCLAHDE_00786 1e-205 M Glycosyl hydrolases family 25
NHCLAHDE_00787 2.8e-157 cinI S Serine hydrolase (FSH1)
NHCLAHDE_00788 4.3e-298 S Predicted membrane protein (DUF2207)
NHCLAHDE_00789 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NHCLAHDE_00791 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
NHCLAHDE_00792 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHCLAHDE_00793 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NHCLAHDE_00794 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NHCLAHDE_00795 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NHCLAHDE_00796 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHCLAHDE_00797 3.4e-71 yqhY S Asp23 family, cell envelope-related function
NHCLAHDE_00798 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHCLAHDE_00799 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHCLAHDE_00800 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHCLAHDE_00801 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHCLAHDE_00802 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHCLAHDE_00803 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NHCLAHDE_00804 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
NHCLAHDE_00805 1.1e-77 6.3.3.2 S ASCH
NHCLAHDE_00806 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NHCLAHDE_00807 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHCLAHDE_00808 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHCLAHDE_00809 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHCLAHDE_00810 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHCLAHDE_00811 1.1e-138 stp 3.1.3.16 T phosphatase
NHCLAHDE_00812 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NHCLAHDE_00813 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHCLAHDE_00814 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NHCLAHDE_00815 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
NHCLAHDE_00816 1.4e-30
NHCLAHDE_00817 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NHCLAHDE_00818 1.5e-56 asp S Asp23 family, cell envelope-related function
NHCLAHDE_00819 1.7e-304 yloV S DAK2 domain fusion protein YloV
NHCLAHDE_00820 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHCLAHDE_00821 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHCLAHDE_00822 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHCLAHDE_00823 3.1e-192 oppD P Belongs to the ABC transporter superfamily
NHCLAHDE_00824 1.5e-170 oppF P Belongs to the ABC transporter superfamily
NHCLAHDE_00825 2.6e-172 oppB P ABC transporter permease
NHCLAHDE_00826 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
NHCLAHDE_00827 9.7e-46 oppA E ABC transporter substrate-binding protein
NHCLAHDE_00828 5.3e-80
NHCLAHDE_00829 2e-295 S SLAP domain
NHCLAHDE_00830 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHCLAHDE_00831 1.6e-171 2.7.1.2 GK ROK family
NHCLAHDE_00832 6.6e-44
NHCLAHDE_00833 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHCLAHDE_00834 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHCLAHDE_00835 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHCLAHDE_00836 1.5e-102 srtA 3.4.22.70 M sortase family
NHCLAHDE_00837 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHCLAHDE_00838 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHCLAHDE_00839 0.0 dnaK O Heat shock 70 kDa protein
NHCLAHDE_00840 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHCLAHDE_00841 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHCLAHDE_00842 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NHCLAHDE_00843 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHCLAHDE_00844 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHCLAHDE_00845 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHCLAHDE_00846 3.2e-47 rplGA J ribosomal protein
NHCLAHDE_00847 8.8e-47 ylxR K Protein of unknown function (DUF448)
NHCLAHDE_00848 1.4e-196 nusA K Participates in both transcription termination and antitermination
NHCLAHDE_00849 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NHCLAHDE_00850 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHCLAHDE_00851 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHCLAHDE_00852 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NHCLAHDE_00853 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
NHCLAHDE_00854 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHCLAHDE_00855 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHCLAHDE_00856 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NHCLAHDE_00857 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHCLAHDE_00858 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NHCLAHDE_00859 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
NHCLAHDE_00860 2.9e-116 plsC 2.3.1.51 I Acyltransferase
NHCLAHDE_00861 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NHCLAHDE_00862 0.0 pepO 3.4.24.71 O Peptidase family M13
NHCLAHDE_00863 0.0 mdlB V ABC transporter
NHCLAHDE_00864 0.0 mdlA V ABC transporter
NHCLAHDE_00865 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
NHCLAHDE_00866 3e-38 ynzC S UPF0291 protein
NHCLAHDE_00867 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHCLAHDE_00868 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
NHCLAHDE_00869 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
NHCLAHDE_00870 4.6e-213 S SLAP domain
NHCLAHDE_00871 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHCLAHDE_00872 3.6e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NHCLAHDE_00873 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHCLAHDE_00874 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NHCLAHDE_00875 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHCLAHDE_00876 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHCLAHDE_00877 2.7e-258 yfnA E amino acid
NHCLAHDE_00878 0.0 V FtsX-like permease family
NHCLAHDE_00879 4.1e-133 cysA V ABC transporter, ATP-binding protein
NHCLAHDE_00880 3.4e-23
NHCLAHDE_00882 2.5e-288 pipD E Dipeptidase
NHCLAHDE_00883 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHCLAHDE_00884 0.0 smc D Required for chromosome condensation and partitioning
NHCLAHDE_00885 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHCLAHDE_00886 2.1e-308 oppA E ABC transporter substrate-binding protein
NHCLAHDE_00887 3.1e-240 oppA E ABC transporter substrate-binding protein
NHCLAHDE_00888 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NHCLAHDE_00889 1.2e-100 treR K UTRA
NHCLAHDE_00890 3.3e-283 treB G phosphotransferase system
NHCLAHDE_00891 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHCLAHDE_00892 1.9e-191 yrvN L AAA C-terminal domain
NHCLAHDE_00893 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHCLAHDE_00894 9e-83 K Acetyltransferase (GNAT) domain
NHCLAHDE_00895 2.9e-229 S Putative peptidoglycan binding domain
NHCLAHDE_00896 7.5e-95 S ECF-type riboflavin transporter, S component
NHCLAHDE_00897 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NHCLAHDE_00898 9.3e-204 pbpX1 V Beta-lactamase
NHCLAHDE_00899 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
NHCLAHDE_00900 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHCLAHDE_00901 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
NHCLAHDE_00902 6.1e-114 3.6.1.27 I Acid phosphatase homologues
NHCLAHDE_00903 2.4e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NHCLAHDE_00904 0.0 uvrA3 L excinuclease ABC, A subunit
NHCLAHDE_00905 9.9e-82 C Flavodoxin
NHCLAHDE_00906 1.9e-75 M LysM domain
NHCLAHDE_00907 1.3e-42
NHCLAHDE_00909 4.9e-35
NHCLAHDE_00910 4.5e-76 yniG EGP Major facilitator Superfamily
NHCLAHDE_00911 5.4e-237 L transposase, IS605 OrfB family
NHCLAHDE_00912 1.4e-109 yniG EGP Major facilitator Superfamily
NHCLAHDE_00913 2.4e-128 S cog cog1373
NHCLAHDE_00914 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NHCLAHDE_00915 1.7e-129 manY G PTS system
NHCLAHDE_00916 1e-173 manN G system, mannose fructose sorbose family IID component
NHCLAHDE_00917 1.1e-62 manO S Domain of unknown function (DUF956)
NHCLAHDE_00918 3.3e-158 K Transcriptional regulator
NHCLAHDE_00919 1.3e-85 maa S transferase hexapeptide repeat
NHCLAHDE_00920 1.3e-241 cycA E Amino acid permease
NHCLAHDE_00921 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NHCLAHDE_00922 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NHCLAHDE_00923 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHCLAHDE_00924 3.4e-305 mtlR K Mga helix-turn-helix domain
NHCLAHDE_00925 4.7e-61 mtlR K Mga helix-turn-helix domain
NHCLAHDE_00926 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
NHCLAHDE_00927 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHCLAHDE_00928 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
NHCLAHDE_00929 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
NHCLAHDE_00930 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
NHCLAHDE_00931 2.1e-32
NHCLAHDE_00932 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NHCLAHDE_00933 1.1e-155 K Helix-turn-helix XRE-family like proteins
NHCLAHDE_00934 3.9e-298 V ABC transporter transmembrane region
NHCLAHDE_00935 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NHCLAHDE_00936 1.7e-193 S TerB-C domain
NHCLAHDE_00937 0.0 S membrane
NHCLAHDE_00938 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NHCLAHDE_00939 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHCLAHDE_00940 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHCLAHDE_00941 3.1e-119 gluP 3.4.21.105 S Rhomboid family
NHCLAHDE_00942 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NHCLAHDE_00943 1.5e-65 yqhL P Rhodanese-like protein
NHCLAHDE_00944 1e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHCLAHDE_00945 3e-221 ynbB 4.4.1.1 P aluminum resistance
NHCLAHDE_00946 2e-263 glnA 6.3.1.2 E glutamine synthetase
NHCLAHDE_00947 1.5e-169
NHCLAHDE_00948 1.7e-147
NHCLAHDE_00949 9.5e-18
NHCLAHDE_00950 0.0 snf 2.7.11.1 KL domain protein
NHCLAHDE_00951 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHCLAHDE_00952 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHCLAHDE_00953 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHCLAHDE_00954 5.6e-183 K Transcriptional regulator
NHCLAHDE_00955 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
NHCLAHDE_00956 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHCLAHDE_00957 4e-57 K Helix-turn-helix domain
NHCLAHDE_00958 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NHCLAHDE_00959 2.8e-48 S Peptidase propeptide and YPEB domain
NHCLAHDE_00960 8.3e-138 L An automated process has identified a potential problem with this gene model
NHCLAHDE_00962 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHCLAHDE_00963 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NHCLAHDE_00964 1.7e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NHCLAHDE_00965 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHCLAHDE_00966 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NHCLAHDE_00967 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NHCLAHDE_00968 9.7e-52 S Iron-sulfur cluster assembly protein
NHCLAHDE_00969 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NHCLAHDE_00970 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NHCLAHDE_00971 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NHCLAHDE_00972 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHCLAHDE_00973 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHCLAHDE_00974 2.6e-35 yaaA S S4 domain protein YaaA
NHCLAHDE_00975 4e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHCLAHDE_00976 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHCLAHDE_00977 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHCLAHDE_00978 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NHCLAHDE_00979 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHCLAHDE_00980 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHCLAHDE_00981 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NHCLAHDE_00982 5.7e-69 rplI J Binds to the 23S rRNA
NHCLAHDE_00983 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NHCLAHDE_00984 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
NHCLAHDE_00985 3.7e-168 degV S DegV family
NHCLAHDE_00986 4.2e-135 V ABC transporter transmembrane region
NHCLAHDE_00987 6.7e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NHCLAHDE_00989 1.4e-16
NHCLAHDE_00990 7.5e-152 I Protein of unknown function (DUF2974)
NHCLAHDE_00991 7.7e-50 I Protein of unknown function (DUF2974)
NHCLAHDE_00992 9.2e-119 yhiD S MgtC family
NHCLAHDE_00994 7.6e-25 S SLAP domain
NHCLAHDE_00995 4.3e-24 S SLAP domain
NHCLAHDE_00996 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NHCLAHDE_00997 9e-98
NHCLAHDE_00998 4.9e-108 K LysR substrate binding domain
NHCLAHDE_00999 1e-20
NHCLAHDE_01000 2.3e-215 S Sterol carrier protein domain
NHCLAHDE_01001 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NHCLAHDE_01002 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
NHCLAHDE_01003 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHCLAHDE_01004 8.8e-234 arcA 3.5.3.6 E Arginine
NHCLAHDE_01005 9e-137 lysR5 K LysR substrate binding domain
NHCLAHDE_01006 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NHCLAHDE_01007 1e-48 S Metal binding domain of Ada
NHCLAHDE_01008 7.3e-126 S Alpha/beta hydrolase family
NHCLAHDE_01009 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
NHCLAHDE_01010 4.4e-140 ypuA S Protein of unknown function (DUF1002)
NHCLAHDE_01011 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHCLAHDE_01012 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
NHCLAHDE_01013 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHCLAHDE_01014 9.3e-86
NHCLAHDE_01015 2e-310 E Amino acid permease
NHCLAHDE_01017 3e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHCLAHDE_01018 2.2e-90 2.7.7.65 T GGDEF domain
NHCLAHDE_01019 8.2e-36
NHCLAHDE_01020 8.9e-112 ica2 GT2 M Glycosyl transferase family group 2
NHCLAHDE_01021 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
NHCLAHDE_01022 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NHCLAHDE_01023 1e-149 D Alpha beta
NHCLAHDE_01024 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHCLAHDE_01025 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHCLAHDE_01026 8.3e-143 licT K CAT RNA binding domain
NHCLAHDE_01027 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NHCLAHDE_01028 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHCLAHDE_01029 1.6e-118
NHCLAHDE_01030 1.8e-75 K Penicillinase repressor
NHCLAHDE_01031 3.2e-147 S hydrolase
NHCLAHDE_01032 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHCLAHDE_01033 2e-172 ybbR S YbbR-like protein
NHCLAHDE_01034 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHCLAHDE_01035 7.3e-208 potD P ABC transporter
NHCLAHDE_01036 4.8e-127 potC P ABC transporter permease
NHCLAHDE_01037 1.3e-129 potB P ABC transporter permease
NHCLAHDE_01038 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHCLAHDE_01039 2e-163 murB 1.3.1.98 M Cell wall formation
NHCLAHDE_01040 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
NHCLAHDE_01041 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NHCLAHDE_01042 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NHCLAHDE_01043 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHCLAHDE_01044 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
NHCLAHDE_01045 1.2e-94
NHCLAHDE_01046 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHCLAHDE_01047 5.4e-203 xerS L Belongs to the 'phage' integrase family
NHCLAHDE_01048 4.1e-67
NHCLAHDE_01049 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
NHCLAHDE_01050 5.8e-211 M Glycosyl hydrolases family 25
NHCLAHDE_01051 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHCLAHDE_01052 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHCLAHDE_01053 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHCLAHDE_01054 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHCLAHDE_01055 2.5e-39 rpmE2 J Ribosomal protein L31
NHCLAHDE_01056 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
NHCLAHDE_01057 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
NHCLAHDE_01058 9.5e-297 ybeC E amino acid
NHCLAHDE_01059 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHCLAHDE_01060 2.1e-42
NHCLAHDE_01061 1.2e-50
NHCLAHDE_01062 6.8e-184 5.3.3.2 C FMN-dependent dehydrogenase
NHCLAHDE_01063 1.1e-141 yfeO P Voltage gated chloride channel
NHCLAHDE_01064 9e-121
NHCLAHDE_01065 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
NHCLAHDE_01066 3.9e-186 S Putative peptidoglycan binding domain
NHCLAHDE_01067 4e-16
NHCLAHDE_01068 7.9e-92 liaI S membrane
NHCLAHDE_01069 6.6e-70 XK27_02470 K LytTr DNA-binding domain
NHCLAHDE_01070 1.2e-18 S Sugar efflux transporter for intercellular exchange
NHCLAHDE_01071 1.3e-250 dtpT U amino acid peptide transporter
NHCLAHDE_01072 0.0 pepN 3.4.11.2 E aminopeptidase
NHCLAHDE_01073 2.8e-47 lysM M LysM domain
NHCLAHDE_01074 1.3e-174
NHCLAHDE_01075 1.7e-152 mdtG EGP Major facilitator Superfamily
NHCLAHDE_01076 6.9e-47 mdtG EGP Major facilitator Superfamily
NHCLAHDE_01077 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHCLAHDE_01079 2e-178 MA20_14895 S Conserved hypothetical protein 698
NHCLAHDE_01080 1.1e-83 dps P Belongs to the Dps family
NHCLAHDE_01081 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
NHCLAHDE_01082 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NHCLAHDE_01083 1.8e-58 S Putative adhesin
NHCLAHDE_01084 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
NHCLAHDE_01085 2e-234 mepA V MATE efflux family protein
NHCLAHDE_01087 1.6e-25 K Helix-turn-helix XRE-family like proteins
NHCLAHDE_01088 1.2e-11
NHCLAHDE_01089 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
NHCLAHDE_01090 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHCLAHDE_01091 5.9e-264 lctP C L-lactate permease
NHCLAHDE_01092 5e-129 znuB U ABC 3 transport family
NHCLAHDE_01093 1.6e-117 fhuC P ABC transporter
NHCLAHDE_01094 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
NHCLAHDE_01095 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
NHCLAHDE_01096 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
NHCLAHDE_01097 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NHCLAHDE_01098 1.8e-136 fruR K DeoR C terminal sensor domain
NHCLAHDE_01099 1.8e-218 natB CP ABC-2 family transporter protein
NHCLAHDE_01100 1.1e-164 natA S ABC transporter, ATP-binding protein
NHCLAHDE_01101 1.7e-67
NHCLAHDE_01102 2e-23
NHCLAHDE_01103 8.2e-31 yozG K Transcriptional regulator
NHCLAHDE_01104 3.7e-83
NHCLAHDE_01105 3e-21
NHCLAHDE_01109 2.2e-129 blpT
NHCLAHDE_01110 1.4e-107 M Transport protein ComB
NHCLAHDE_01111 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHCLAHDE_01112 3.7e-20
NHCLAHDE_01113 3.2e-139
NHCLAHDE_01114 3.7e-261 V ABC transporter transmembrane region
NHCLAHDE_01115 1.4e-37 S Putative adhesin
NHCLAHDE_01116 5.3e-26
NHCLAHDE_01117 8.5e-41 ptsH G phosphocarrier protein HPR
NHCLAHDE_01118 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHCLAHDE_01119 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHCLAHDE_01120 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHCLAHDE_01121 3.3e-132 coiA 3.6.4.12 S Competence protein
NHCLAHDE_01122 4e-13 coiA 3.6.4.12 S Competence protein
NHCLAHDE_01123 4.6e-114 yjbH Q Thioredoxin
NHCLAHDE_01124 6.8e-110 yjbK S CYTH
NHCLAHDE_01125 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
NHCLAHDE_01126 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHCLAHDE_01127 1.2e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHCLAHDE_01128 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NHCLAHDE_01129 4.2e-92 S SNARE associated Golgi protein
NHCLAHDE_01130 6.8e-60 divIC D Septum formation initiator
NHCLAHDE_01131 1.8e-62 yabR J S1 RNA binding domain
NHCLAHDE_01132 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHCLAHDE_01133 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHCLAHDE_01134 2.2e-165 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHCLAHDE_01135 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHCLAHDE_01136 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NHCLAHDE_01137 1.4e-83 K FR47-like protein
NHCLAHDE_01138 1.6e-08
NHCLAHDE_01139 1.6e-08
NHCLAHDE_01140 1.6e-08
NHCLAHDE_01142 3.5e-70 yebR 1.8.4.14 T GAF domain-containing protein
NHCLAHDE_01143 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
NHCLAHDE_01144 4.7e-25 S Protein conserved in bacteria
NHCLAHDE_01145 1.1e-11
NHCLAHDE_01146 2e-83
NHCLAHDE_01147 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
NHCLAHDE_01148 5.8e-186 XK27_05540 S DUF218 domain
NHCLAHDE_01149 1.1e-110
NHCLAHDE_01150 4.3e-107
NHCLAHDE_01151 6.3e-50 yicL EG EamA-like transporter family
NHCLAHDE_01152 3.1e-48 S Domain of unknown function (DUF4811)
NHCLAHDE_01153 1.4e-262 lmrB EGP Major facilitator Superfamily
NHCLAHDE_01154 4.2e-77 K MerR HTH family regulatory protein
NHCLAHDE_01155 3.1e-139 S Cysteine-rich secretory protein family
NHCLAHDE_01156 4.6e-274 ycaM E amino acid
NHCLAHDE_01157 2.8e-290
NHCLAHDE_01159 2.6e-189 cggR K Putative sugar-binding domain
NHCLAHDE_01160 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHCLAHDE_01161 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NHCLAHDE_01162 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHCLAHDE_01163 1.4e-52 EGP Sugar (and other) transporter
NHCLAHDE_01164 1e-104
NHCLAHDE_01165 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NHCLAHDE_01166 0.0 copA 3.6.3.54 P P-type ATPase
NHCLAHDE_01167 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NHCLAHDE_01168 4.9e-58 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NHCLAHDE_01169 2.4e-36
NHCLAHDE_01172 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHCLAHDE_01173 0.0 uup S ABC transporter, ATP-binding protein
NHCLAHDE_01174 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NHCLAHDE_01175 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NHCLAHDE_01176 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NHCLAHDE_01177 7.7e-22
NHCLAHDE_01178 9.3e-64 L PFAM IS66 Orf2 family protein
NHCLAHDE_01179 8.7e-34 S Transposase C of IS166 homeodomain
NHCLAHDE_01180 1.1e-187 L Transposase IS66 family
NHCLAHDE_01181 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHCLAHDE_01182 6.7e-56 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NHCLAHDE_01183 2.2e-15 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NHCLAHDE_01184 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NHCLAHDE_01185 2.2e-85 S ECF transporter, substrate-specific component
NHCLAHDE_01186 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
NHCLAHDE_01187 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHCLAHDE_01188 1.8e-59 yabA L Involved in initiation control of chromosome replication
NHCLAHDE_01189 1.5e-155 holB 2.7.7.7 L DNA polymerase III
NHCLAHDE_01190 8.9e-53 yaaQ S Cyclic-di-AMP receptor
NHCLAHDE_01191 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHCLAHDE_01192 1.1e-34 S Protein of unknown function (DUF2508)
NHCLAHDE_01193 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHCLAHDE_01194 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHCLAHDE_01195 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
NHCLAHDE_01196 5.7e-106 2.4.1.58 GT8 M family 8
NHCLAHDE_01197 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHCLAHDE_01198 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHCLAHDE_01199 9e-26
NHCLAHDE_01200 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
NHCLAHDE_01201 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
NHCLAHDE_01202 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHCLAHDE_01203 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHCLAHDE_01204 1.5e-11 GT2,GT4 M family 8
NHCLAHDE_01205 2.8e-90 L An automated process has identified a potential problem with this gene model
NHCLAHDE_01206 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
NHCLAHDE_01207 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHCLAHDE_01208 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHCLAHDE_01209 6.5e-154 pstA P Phosphate transport system permease protein PstA
NHCLAHDE_01210 1.1e-114 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NHCLAHDE_01211 0.0 XK27_08315 M Sulfatase
NHCLAHDE_01212 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHCLAHDE_01213 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NHCLAHDE_01214 1.4e-98 G Aldose 1-epimerase
NHCLAHDE_01215 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHCLAHDE_01216 2.1e-116
NHCLAHDE_01217 2.1e-130
NHCLAHDE_01218 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
NHCLAHDE_01219 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NHCLAHDE_01220 0.0 yjbQ P TrkA C-terminal domain protein
NHCLAHDE_01221 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NHCLAHDE_01222 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHCLAHDE_01224 1.4e-104 S SLAP domain
NHCLAHDE_01225 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHCLAHDE_01226 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHCLAHDE_01227 1.1e-25
NHCLAHDE_01228 1.2e-77 K DNA-templated transcription, initiation
NHCLAHDE_01229 5.3e-41
NHCLAHDE_01231 3.1e-131 S SLAP domain
NHCLAHDE_01232 4.3e-40 S Protein of unknown function (DUF2922)
NHCLAHDE_01233 5.5e-30
NHCLAHDE_01235 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
NHCLAHDE_01236 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
NHCLAHDE_01237 6.1e-216 3.6.3.6 P Cation transporter/ATPase, N-terminus
NHCLAHDE_01238 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
NHCLAHDE_01239 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
NHCLAHDE_01240 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
NHCLAHDE_01241 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
NHCLAHDE_01242 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHCLAHDE_01243 7.5e-100 J Acetyltransferase (GNAT) domain
NHCLAHDE_01244 1.4e-110 yjbF S SNARE associated Golgi protein
NHCLAHDE_01245 2.7e-151 I alpha/beta hydrolase fold
NHCLAHDE_01246 5.2e-156 hipB K Helix-turn-helix
NHCLAHDE_01247 1.4e-15 S cog cog1373
NHCLAHDE_01248 1e-30 S cog cog1373
NHCLAHDE_01249 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
NHCLAHDE_01250 3.6e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NHCLAHDE_01252 6.1e-48 E Pfam:DUF955
NHCLAHDE_01253 1.7e-23 relB L Addiction module antitoxin, RelB DinJ family
NHCLAHDE_01254 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHCLAHDE_01256 3.7e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NHCLAHDE_01258 1.1e-23 S CAAX protease self-immunity
NHCLAHDE_01260 4.1e-34
NHCLAHDE_01261 1e-66 doc S Fic/DOC family
NHCLAHDE_01263 9.4e-51 L An automated process has identified a potential problem with this gene model
NHCLAHDE_01264 7.9e-16 L An automated process has identified a potential problem with this gene model
NHCLAHDE_01266 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
NHCLAHDE_01267 9.7e-205 gatC G PTS system sugar-specific permease component
NHCLAHDE_01268 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NHCLAHDE_01269 4.6e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHCLAHDE_01270 8.3e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NHCLAHDE_01271 2.4e-99 L An automated process has identified a potential problem with this gene model
NHCLAHDE_01272 3.3e-241 V N-6 DNA Methylase
NHCLAHDE_01273 3.8e-82 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
NHCLAHDE_01274 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHCLAHDE_01275 3.8e-99 S Tetratricopeptide repeat protein
NHCLAHDE_01276 1.4e-75 S Tetratricopeptide repeat protein
NHCLAHDE_01277 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHCLAHDE_01278 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NHCLAHDE_01279 2.7e-211 rpsA 1.17.7.4 J Ribosomal protein S1
NHCLAHDE_01280 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NHCLAHDE_01281 2.7e-18 M Lysin motif
NHCLAHDE_01282 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHCLAHDE_01283 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHCLAHDE_01284 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHCLAHDE_01285 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHCLAHDE_01286 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHCLAHDE_01287 2.9e-165 xerD D recombinase XerD
NHCLAHDE_01288 1e-167 cvfB S S1 domain
NHCLAHDE_01289 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NHCLAHDE_01290 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHCLAHDE_01291 7.4e-40 yabO J S4 domain protein
NHCLAHDE_01292 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHCLAHDE_01293 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHCLAHDE_01294 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHCLAHDE_01295 3.4e-129 S (CBS) domain
NHCLAHDE_01296 2.3e-48 S SLAP domain
NHCLAHDE_01297 3.5e-136 S SLAP domain
NHCLAHDE_01298 8e-210
NHCLAHDE_01299 1.2e-18
NHCLAHDE_01300 7.3e-175 EGP Sugar (and other) transporter
NHCLAHDE_01301 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
NHCLAHDE_01302 5.6e-95 V ABC-type multidrug transport system, ATPase and permease components
NHCLAHDE_01303 1.3e-157 V ABC-type multidrug transport system, ATPase and permease components
NHCLAHDE_01304 4.9e-282 L AAA domain
NHCLAHDE_01305 4.2e-61 V Abi-like protein
NHCLAHDE_01306 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NHCLAHDE_01310 7.7e-39 L Transposase
NHCLAHDE_01311 3.3e-183 scrR K helix_turn _helix lactose operon repressor
NHCLAHDE_01312 3.7e-295 scrB 3.2.1.26 GH32 G invertase
NHCLAHDE_01313 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
NHCLAHDE_01314 2.3e-181 M CHAP domain
NHCLAHDE_01315 3.5e-75
NHCLAHDE_01316 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHCLAHDE_01317 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHCLAHDE_01318 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHCLAHDE_01319 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHCLAHDE_01320 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHCLAHDE_01321 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHCLAHDE_01322 9.6e-41 yajC U Preprotein translocase
NHCLAHDE_01323 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHCLAHDE_01324 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHCLAHDE_01325 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NHCLAHDE_01326 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHCLAHDE_01327 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHCLAHDE_01328 2e-42 yrzL S Belongs to the UPF0297 family
NHCLAHDE_01329 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHCLAHDE_01330 1.1e-50 yrzB S Belongs to the UPF0473 family
NHCLAHDE_01331 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHCLAHDE_01332 3.5e-54 trxA O Belongs to the thioredoxin family
NHCLAHDE_01333 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHCLAHDE_01334 1.1e-71 yslB S Protein of unknown function (DUF2507)
NHCLAHDE_01335 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NHCLAHDE_01336 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHCLAHDE_01337 7.7e-30 ropB K Helix-turn-helix domain
NHCLAHDE_01338 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHCLAHDE_01339 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
NHCLAHDE_01340 4.4e-129 K Transcriptional regulatory protein, C terminal
NHCLAHDE_01341 7.7e-67 S SdpI/YhfL protein family
NHCLAHDE_01342 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHCLAHDE_01343 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
NHCLAHDE_01344 2.5e-89 M Protein of unknown function (DUF3737)
NHCLAHDE_01345 7.6e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHCLAHDE_01346 1e-12
NHCLAHDE_01348 5e-15 S Domain of Unknown Function with PDB structure (DUF3850)
NHCLAHDE_01349 2.2e-97 D VirC1 protein
NHCLAHDE_01351 5e-39 relB L RelB antitoxin
NHCLAHDE_01352 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NHCLAHDE_01353 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
NHCLAHDE_01354 2.2e-134 glvR K Helix-turn-helix domain, rpiR family
NHCLAHDE_01355 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
NHCLAHDE_01356 5.9e-09
NHCLAHDE_01357 4.4e-43
NHCLAHDE_01358 8.7e-66 2.7.1.191 G PTS system fructose IIA component
NHCLAHDE_01359 0.0 3.6.3.8 P P-type ATPase
NHCLAHDE_01360 4.9e-125
NHCLAHDE_01361 3.5e-241 S response to antibiotic
NHCLAHDE_01362 7e-22
NHCLAHDE_01363 9.3e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHCLAHDE_01364 0.0 L AAA domain
NHCLAHDE_01365 1e-226 yhaO L Ser Thr phosphatase family protein
NHCLAHDE_01366 7.2e-56 yheA S Belongs to the UPF0342 family
NHCLAHDE_01367 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHCLAHDE_01368 3.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHCLAHDE_01369 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NHCLAHDE_01370 3.2e-10 S Domain of unknown function DUF87
NHCLAHDE_01371 1.2e-63 S SIR2-like domain
NHCLAHDE_01372 5.7e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
NHCLAHDE_01373 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
NHCLAHDE_01374 3.4e-42 S RloB-like protein
NHCLAHDE_01375 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
NHCLAHDE_01376 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
NHCLAHDE_01377 0.0 S SLAP domain
NHCLAHDE_01379 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
NHCLAHDE_01380 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
NHCLAHDE_01381 1.5e-239 G Bacterial extracellular solute-binding protein
NHCLAHDE_01382 5.7e-18
NHCLAHDE_01384 1.9e-117 cps1D M Domain of unknown function (DUF4422)
NHCLAHDE_01385 6.7e-110 rfbP M Bacterial sugar transferase
NHCLAHDE_01386 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
NHCLAHDE_01387 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NHCLAHDE_01388 6.5e-146 epsB M biosynthesis protein
NHCLAHDE_01389 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NHCLAHDE_01391 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHCLAHDE_01392 3.5e-175 S Cysteine-rich secretory protein family
NHCLAHDE_01393 1.6e-41
NHCLAHDE_01394 2.6e-118 M NlpC/P60 family
NHCLAHDE_01395 1.4e-136 M NlpC P60 family protein
NHCLAHDE_01396 5e-88 M NlpC/P60 family
NHCLAHDE_01397 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
NHCLAHDE_01398 3.9e-42
NHCLAHDE_01399 2.9e-279 S O-antigen ligase like membrane protein
NHCLAHDE_01400 3.3e-112
NHCLAHDE_01401 9.5e-161 tnpB L Putative transposase DNA-binding domain
NHCLAHDE_01402 1e-53 tnpB L Putative transposase DNA-binding domain
NHCLAHDE_01403 5.5e-77 nrdI F NrdI Flavodoxin like
NHCLAHDE_01404 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHCLAHDE_01405 2.5e-68
NHCLAHDE_01406 9.1e-112 yvpB S Peptidase_C39 like family
NHCLAHDE_01407 1.1e-83 S Threonine/Serine exporter, ThrE
NHCLAHDE_01408 2.4e-136 thrE S Putative threonine/serine exporter
NHCLAHDE_01409 8.9e-292 S ABC transporter
NHCLAHDE_01410 8.3e-58
NHCLAHDE_01411 5e-72 rimL J Acetyltransferase (GNAT) domain
NHCLAHDE_01412 1.4e-34
NHCLAHDE_01413 1.2e-30
NHCLAHDE_01414 1.8e-111 S Protein of unknown function (DUF554)
NHCLAHDE_01415 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NHCLAHDE_01416 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NHCLAHDE_01417 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NHCLAHDE_01418 6.7e-98 M ErfK YbiS YcfS YnhG
NHCLAHDE_01419 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHCLAHDE_01420 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHCLAHDE_01422 4.7e-46 pspC KT PspC domain
NHCLAHDE_01423 3.3e-237 L COG2963 Transposase and inactivated derivatives
NHCLAHDE_01424 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHCLAHDE_01425 4.8e-34 S reductase
NHCLAHDE_01426 4.4e-39 S reductase
NHCLAHDE_01427 2.7e-32 S reductase
NHCLAHDE_01428 1.3e-148 yxeH S hydrolase
NHCLAHDE_01429 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHCLAHDE_01430 1.1e-243 yfnA E Amino Acid
NHCLAHDE_01431 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
NHCLAHDE_01432 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHCLAHDE_01433 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHCLAHDE_01434 2.2e-292 I Acyltransferase
NHCLAHDE_01435 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHCLAHDE_01436 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHCLAHDE_01437 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
NHCLAHDE_01438 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NHCLAHDE_01439 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NHCLAHDE_01440 2.3e-23 S Protein of unknown function (DUF2929)
NHCLAHDE_01441 0.0 dnaE 2.7.7.7 L DNA polymerase
NHCLAHDE_01442 5.4e-13
NHCLAHDE_01443 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHCLAHDE_01444 0.0 G Belongs to the glycosyl hydrolase 31 family
NHCLAHDE_01445 8.7e-145 I alpha/beta hydrolase fold
NHCLAHDE_01446 4.9e-129 yibF S overlaps another CDS with the same product name
NHCLAHDE_01447 2.2e-202 yibE S overlaps another CDS with the same product name
NHCLAHDE_01448 1.4e-112
NHCLAHDE_01449 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NHCLAHDE_01450 6.4e-224 S Cysteine-rich secretory protein family
NHCLAHDE_01451 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHCLAHDE_01452 1.3e-258 glnPH2 P ABC transporter permease
NHCLAHDE_01453 2.8e-135
NHCLAHDE_01454 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
NHCLAHDE_01455 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHCLAHDE_01456 5.6e-36
NHCLAHDE_01457 1.3e-273 pipD E Dipeptidase
NHCLAHDE_01458 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NHCLAHDE_01459 3.3e-176 hrtB V ABC transporter permease
NHCLAHDE_01460 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
NHCLAHDE_01461 3.5e-111 G phosphoglycerate mutase
NHCLAHDE_01462 2e-140 aroD S Alpha/beta hydrolase family
NHCLAHDE_01463 2.2e-142 S Belongs to the UPF0246 family
NHCLAHDE_01464 3.8e-115 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NHCLAHDE_01465 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NHCLAHDE_01466 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
NHCLAHDE_01467 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
NHCLAHDE_01468 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
NHCLAHDE_01469 7e-87 gtcA S Teichoic acid glycosylation protein
NHCLAHDE_01470 4.1e-80 fld C Flavodoxin
NHCLAHDE_01471 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
NHCLAHDE_01472 3.6e-163 yihY S Belongs to the UPF0761 family
NHCLAHDE_01473 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHCLAHDE_01474 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
NHCLAHDE_01475 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NHCLAHDE_01476 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
NHCLAHDE_01477 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHCLAHDE_01478 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHCLAHDE_01479 1.4e-115 mmuP E amino acid
NHCLAHDE_01480 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
NHCLAHDE_01481 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
NHCLAHDE_01482 1.7e-284 E Amino acid permease
NHCLAHDE_01483 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NHCLAHDE_01484 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
NHCLAHDE_01485 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NHCLAHDE_01486 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
NHCLAHDE_01487 2.8e-119 3.6.1.55 F NUDIX domain
NHCLAHDE_01488 6.9e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
NHCLAHDE_01489 2.7e-83 S Protein of unknown function (DUF1211)
NHCLAHDE_01491 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NHCLAHDE_01492 7.5e-103 G Phosphoglycerate mutase family
NHCLAHDE_01493 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
NHCLAHDE_01494 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NHCLAHDE_01495 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NHCLAHDE_01496 3.5e-71 yqeY S YqeY-like protein
NHCLAHDE_01497 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
NHCLAHDE_01498 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHCLAHDE_01499 6.2e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHCLAHDE_01500 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
NHCLAHDE_01501 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NHCLAHDE_01502 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NHCLAHDE_01503 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHCLAHDE_01504 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHCLAHDE_01505 1.4e-127 S Peptidase family M23
NHCLAHDE_01506 4.8e-81 mutT 3.6.1.55 F NUDIX domain
NHCLAHDE_01507 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NHCLAHDE_01508 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHCLAHDE_01509 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHCLAHDE_01510 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
NHCLAHDE_01511 9.6e-124 skfE V ATPases associated with a variety of cellular activities
NHCLAHDE_01512 4.5e-141
NHCLAHDE_01513 5.1e-137
NHCLAHDE_01514 2.1e-143
NHCLAHDE_01515 1.4e-26
NHCLAHDE_01516 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NHCLAHDE_01517 6.3e-142
NHCLAHDE_01518 9.7e-169
NHCLAHDE_01519 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NHCLAHDE_01520 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
NHCLAHDE_01521 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHCLAHDE_01522 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NHCLAHDE_01523 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NHCLAHDE_01524 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NHCLAHDE_01525 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NHCLAHDE_01526 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NHCLAHDE_01527 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NHCLAHDE_01528 9.2e-89 ypmB S Protein conserved in bacteria
NHCLAHDE_01529 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NHCLAHDE_01530 1.3e-114 dnaD L DnaD domain protein
NHCLAHDE_01531 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHCLAHDE_01532 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NHCLAHDE_01533 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHCLAHDE_01534 1e-107 ypsA S Belongs to the UPF0398 family
NHCLAHDE_01535 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHCLAHDE_01536 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NHCLAHDE_01537 1e-242 cpdA S Calcineurin-like phosphoesterase
NHCLAHDE_01538 3.4e-79
NHCLAHDE_01539 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
NHCLAHDE_01540 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHCLAHDE_01541 2.1e-168 dnaI L Primosomal protein DnaI
NHCLAHDE_01542 5.1e-251 dnaB L Replication initiation and membrane attachment
NHCLAHDE_01543 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHCLAHDE_01544 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHCLAHDE_01545 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHCLAHDE_01546 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHCLAHDE_01547 3.5e-25 qmcA O prohibitin homologues
NHCLAHDE_01548 7.4e-105 qmcA O prohibitin homologues
NHCLAHDE_01549 8e-51 L RelB antitoxin
NHCLAHDE_01550 4.5e-188 S Bacteriocin helveticin-J
NHCLAHDE_01551 4.4e-283 M Peptidase family M1 domain
NHCLAHDE_01552 1.8e-176 S SLAP domain
NHCLAHDE_01553 6.9e-218 mepA V MATE efflux family protein
NHCLAHDE_01554 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NHCLAHDE_01555 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHCLAHDE_01556 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NHCLAHDE_01558 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHCLAHDE_01559 6.5e-221 ecsB U ABC transporter
NHCLAHDE_01560 5.7e-135 ecsA V ABC transporter, ATP-binding protein
NHCLAHDE_01561 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
NHCLAHDE_01562 3.9e-25
NHCLAHDE_01563 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHCLAHDE_01564 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
NHCLAHDE_01565 1.1e-265
NHCLAHDE_01566 2.4e-51 S Domain of unknown function DUF1829
NHCLAHDE_01567 1.2e-210 S Bacterial protein of unknown function (DUF871)
NHCLAHDE_01569 2.3e-43 ybhL S Belongs to the BI1 family
NHCLAHDE_01570 1.9e-19
NHCLAHDE_01571 9.9e-39 3.6.3.6 P Cation transporter/ATPase, N-terminus
NHCLAHDE_01572 1.6e-96 ybaT E Amino acid permease
NHCLAHDE_01574 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
NHCLAHDE_01575 1.4e-22 S CAAX protease self-immunity
NHCLAHDE_01576 2.4e-17 S CAAX protease self-immunity
NHCLAHDE_01577 1.6e-147 S cog cog1373
NHCLAHDE_01578 0.0 4.2.1.53 S Myosin-crossreactive antigen
NHCLAHDE_01579 2e-91 yxdD K Bacterial regulatory proteins, tetR family
NHCLAHDE_01580 1.9e-259 emrY EGP Major facilitator Superfamily
NHCLAHDE_01585 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
NHCLAHDE_01586 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHCLAHDE_01587 6.3e-201 pbpX V Beta-lactamase
NHCLAHDE_01588 2.8e-244 nhaC C Na H antiporter NhaC
NHCLAHDE_01589 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
NHCLAHDE_01590 2.6e-57
NHCLAHDE_01591 4.3e-108 ybhL S Belongs to the BI1 family
NHCLAHDE_01592 2.7e-171 yegS 2.7.1.107 G Lipid kinase
NHCLAHDE_01593 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHCLAHDE_01594 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHCLAHDE_01595 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHCLAHDE_01596 5.8e-203 camS S sex pheromone
NHCLAHDE_01597 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHCLAHDE_01598 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NHCLAHDE_01599 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NHCLAHDE_01601 4.1e-83 ydcK S Belongs to the SprT family
NHCLAHDE_01602 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
NHCLAHDE_01603 3e-257 epsU S Polysaccharide biosynthesis protein
NHCLAHDE_01604 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHCLAHDE_01605 0.0 pacL 3.6.3.8 P P-type ATPase
NHCLAHDE_01606 1.4e-204 tnpB L Putative transposase DNA-binding domain
NHCLAHDE_01607 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHCLAHDE_01608 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHCLAHDE_01609 1.7e-204 csaB M Glycosyl transferases group 1
NHCLAHDE_01610 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NHCLAHDE_01611 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NHCLAHDE_01612 4.6e-123 gntR1 K UTRA
NHCLAHDE_01613 3.3e-179
NHCLAHDE_01614 3.4e-45 oppA2 E ABC transporter, substratebinding protein
NHCLAHDE_01615 4.4e-239 oppA2 E ABC transporter, substratebinding protein
NHCLAHDE_01618 3.2e-240 npr 1.11.1.1 C NADH oxidase
NHCLAHDE_01619 6.6e-11
NHCLAHDE_01620 1.3e-22 3.6.4.12 S transposase or invertase
NHCLAHDE_01621 4.3e-227 slpX S SLAP domain
NHCLAHDE_01622 3.7e-143 K SIS domain
NHCLAHDE_01623 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NHCLAHDE_01624 1.8e-184 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NHCLAHDE_01625 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NHCLAHDE_01627 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NHCLAHDE_01629 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHCLAHDE_01630 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NHCLAHDE_01631 2.6e-89 G Histidine phosphatase superfamily (branch 1)
NHCLAHDE_01632 1.2e-105 G Phosphoglycerate mutase family
NHCLAHDE_01633 6.4e-164 D nuclear chromosome segregation
NHCLAHDE_01634 1.5e-92 yicL EG EamA-like transporter family
NHCLAHDE_01635 5e-165 EG EamA-like transporter family
NHCLAHDE_01636 3.1e-162 EG EamA-like transporter family
NHCLAHDE_01637 2e-32
NHCLAHDE_01638 7.8e-38
NHCLAHDE_01639 2.6e-155
NHCLAHDE_01642 1.8e-81 M NlpC/P60 family
NHCLAHDE_01643 2.1e-131 cobQ S glutamine amidotransferase
NHCLAHDE_01644 6.5e-64 L RelB antitoxin
NHCLAHDE_01645 5.7e-272 P Sodium:sulfate symporter transmembrane region
NHCLAHDE_01646 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
NHCLAHDE_01647 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
NHCLAHDE_01648 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHCLAHDE_01649 9.5e-261 frdC 1.3.5.4 C FAD binding domain
NHCLAHDE_01650 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHCLAHDE_01651 3.4e-73 metI P ABC transporter permease
NHCLAHDE_01652 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHCLAHDE_01653 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
NHCLAHDE_01654 2.4e-175 F DNA/RNA non-specific endonuclease
NHCLAHDE_01655 0.0 aha1 P E1-E2 ATPase
NHCLAHDE_01656 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHCLAHDE_01657 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHCLAHDE_01658 1.2e-250 yifK E Amino acid permease
NHCLAHDE_01659 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
NHCLAHDE_01660 6.2e-87 U TraM recognition site of TraD and TraG
NHCLAHDE_01661 3.9e-32 I mechanosensitive ion channel activity
NHCLAHDE_01663 8.4e-15
NHCLAHDE_01664 1.8e-159 trsE S COG0433 Predicted ATPase
NHCLAHDE_01665 2.1e-32 M Peptidase family M23
NHCLAHDE_01668 2.4e-18 CO COG0526, thiol-disulfide isomerase and thioredoxins
NHCLAHDE_01671 5.5e-36
NHCLAHDE_01672 5e-160 scrR K Periplasmic binding protein domain
NHCLAHDE_01673 1.5e-141 msmE G Bacterial extracellular solute-binding protein
NHCLAHDE_01674 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHCLAHDE_01675 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHCLAHDE_01676 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHCLAHDE_01679 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NHCLAHDE_01680 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
NHCLAHDE_01681 1.8e-230 steT_1 E amino acid
NHCLAHDE_01682 2.2e-139 puuD S peptidase C26
NHCLAHDE_01684 2.7e-171 V HNH endonuclease
NHCLAHDE_01685 6.4e-135 S PFAM Archaeal ATPase
NHCLAHDE_01686 9.2e-248 yifK E Amino acid permease
NHCLAHDE_01687 9.7e-234 cycA E Amino acid permease
NHCLAHDE_01688 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NHCLAHDE_01689 0.0 clpE O AAA domain (Cdc48 subfamily)
NHCLAHDE_01690 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
NHCLAHDE_01691 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHCLAHDE_01692 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
NHCLAHDE_01693 0.0 XK27_06780 V ABC transporter permease
NHCLAHDE_01694 1.9e-36
NHCLAHDE_01695 7.9e-291 ytgP S Polysaccharide biosynthesis protein
NHCLAHDE_01696 2.7e-137 lysA2 M Glycosyl hydrolases family 25
NHCLAHDE_01697 2.3e-133 S Protein of unknown function (DUF975)
NHCLAHDE_01698 7.6e-177 pbpX2 V Beta-lactamase
NHCLAHDE_01699 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHCLAHDE_01700 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHCLAHDE_01701 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
NHCLAHDE_01702 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHCLAHDE_01703 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
NHCLAHDE_01704 4.1e-44
NHCLAHDE_01705 1e-207 ywhK S Membrane
NHCLAHDE_01706 1.5e-80 ykuL S (CBS) domain
NHCLAHDE_01707 0.0 cadA P P-type ATPase
NHCLAHDE_01708 2.8e-205 napA P Sodium/hydrogen exchanger family
NHCLAHDE_01709 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NHCLAHDE_01710 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
NHCLAHDE_01711 4.1e-276 V ABC transporter transmembrane region
NHCLAHDE_01712 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
NHCLAHDE_01713 5.4e-51
NHCLAHDE_01714 4.2e-154 EGP Major facilitator Superfamily
NHCLAHDE_01715 3e-111 ropB K Transcriptional regulator
NHCLAHDE_01716 2.7e-120 S CAAX protease self-immunity
NHCLAHDE_01717 1.6e-194 S DUF218 domain
NHCLAHDE_01718 0.0 macB_3 V ABC transporter, ATP-binding protein
NHCLAHDE_01719 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NHCLAHDE_01720 8.2e-100 S ECF transporter, substrate-specific component
NHCLAHDE_01721 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
NHCLAHDE_01722 3.4e-27
NHCLAHDE_01723 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
NHCLAHDE_01724 5.4e-53 hipB K sequence-specific DNA binding
NHCLAHDE_01725 4.8e-42 S SnoaL-like domain
NHCLAHDE_01726 0.0 L PLD-like domain
NHCLAHDE_01727 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NHCLAHDE_01728 1.4e-190 I transferase activity, transferring acyl groups other than amino-acyl groups
NHCLAHDE_01729 5.6e-179 S PFAM Archaeal ATPase
NHCLAHDE_01730 3.1e-73 S cog cog1373
NHCLAHDE_01732 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHCLAHDE_01733 3.5e-101 ylbE GM NAD(P)H-binding
NHCLAHDE_01734 7.6e-94 S VanZ like family
NHCLAHDE_01735 8.9e-133 yebC K Transcriptional regulatory protein
NHCLAHDE_01736 1.7e-179 comGA NU Type II IV secretion system protein
NHCLAHDE_01737 1.7e-171 comGB NU type II secretion system
NHCLAHDE_01738 3.1e-43 comGC U competence protein ComGC
NHCLAHDE_01739 1.8e-69
NHCLAHDE_01740 2.3e-41
NHCLAHDE_01741 3.8e-77 comGF U Putative Competence protein ComGF
NHCLAHDE_01742 1.6e-21
NHCLAHDE_01743 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
NHCLAHDE_01744 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHCLAHDE_01746 8.5e-151 L Belongs to the 'phage' integrase family
NHCLAHDE_01747 1e-08 S Pfam:DUF955
NHCLAHDE_01748 9.8e-16 K Helix-turn-helix XRE-family like proteins
NHCLAHDE_01749 4e-22 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NHCLAHDE_01750 1e-25 K Helix-turn-helix domain
NHCLAHDE_01752 4.1e-09 S Arc-like DNA binding domain
NHCLAHDE_01754 4e-21 K Conserved phage C-terminus (Phg_2220_C)
NHCLAHDE_01755 1.5e-26 S Domain of unknown function (DUF771)
NHCLAHDE_01761 7.8e-34 S Phage derived protein Gp49-like (DUF891)
NHCLAHDE_01762 7.1e-35 K Helix-turn-helix XRE-family like proteins
NHCLAHDE_01764 1.1e-188 L N-6 DNA Methylase
NHCLAHDE_01765 2.2e-26 S Type I restriction modification DNA specificity domain
NHCLAHDE_01766 3.7e-10 S Single-strand binding protein family
NHCLAHDE_01771 1.5e-12 S SLAP domain
NHCLAHDE_01773 1.4e-24 srtA 3.4.22.70 M sortase family
NHCLAHDE_01775 1.8e-41 M domain protein
NHCLAHDE_01776 7.2e-15 S SLAP domain
NHCLAHDE_01777 4.6e-31 M domain protein
NHCLAHDE_01781 4.1e-46 U TraM recognition site of TraD and TraG
NHCLAHDE_01782 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NHCLAHDE_01783 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NHCLAHDE_01784 2.6e-214 yubA S AI-2E family transporter
NHCLAHDE_01785 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHCLAHDE_01786 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
NHCLAHDE_01787 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NHCLAHDE_01788 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NHCLAHDE_01789 1.9e-236 S Peptidase M16
NHCLAHDE_01790 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
NHCLAHDE_01791 5.2e-97 ymfM S Helix-turn-helix domain
NHCLAHDE_01792 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHCLAHDE_01793 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHCLAHDE_01794 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
NHCLAHDE_01795 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
NHCLAHDE_01796 5.1e-119 yvyE 3.4.13.9 S YigZ family
NHCLAHDE_01797 4.7e-246 comFA L Helicase C-terminal domain protein
NHCLAHDE_01798 9.4e-132 comFC S Competence protein
NHCLAHDE_01799 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHCLAHDE_01800 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHCLAHDE_01801 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHCLAHDE_01802 5.1e-17
NHCLAHDE_01803 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHCLAHDE_01804 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHCLAHDE_01805 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NHCLAHDE_01806 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHCLAHDE_01807 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NHCLAHDE_01808 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHCLAHDE_01809 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHCLAHDE_01810 4.1e-90 S Short repeat of unknown function (DUF308)
NHCLAHDE_01811 6.2e-165 rapZ S Displays ATPase and GTPase activities
NHCLAHDE_01812 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NHCLAHDE_01813 2.1e-171 whiA K May be required for sporulation
NHCLAHDE_01814 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHCLAHDE_01815 0.0 S SH3-like domain
NHCLAHDE_01816 4.9e-111 ybbL S ABC transporter, ATP-binding protein
NHCLAHDE_01817 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
NHCLAHDE_01818 4.8e-28
NHCLAHDE_01821 4.3e-67 K Helix-turn-helix XRE-family like proteins
NHCLAHDE_01822 3.3e-147 malG P ABC transporter permease
NHCLAHDE_01823 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
NHCLAHDE_01824 1.3e-213 malE G Bacterial extracellular solute-binding protein
NHCLAHDE_01825 6.8e-209 msmX P Belongs to the ABC transporter superfamily
NHCLAHDE_01826 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NHCLAHDE_01827 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NHCLAHDE_01828 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NHCLAHDE_01829 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NHCLAHDE_01830 0.0 fhaB M Rib/alpha-like repeat
NHCLAHDE_01831 3.4e-100 2.7.6.5 T Region found in RelA / SpoT proteins
NHCLAHDE_01832 1.2e-104 K response regulator
NHCLAHDE_01833 1.1e-103 sptS 2.7.13.3 T Histidine kinase
NHCLAHDE_01834 2.6e-103 sptS 2.7.13.3 T Histidine kinase
NHCLAHDE_01835 7.2e-209 EGP Major facilitator Superfamily
NHCLAHDE_01836 2.3e-69 O OsmC-like protein
NHCLAHDE_01837 2.2e-85 S Protein of unknown function (DUF805)
NHCLAHDE_01838 2.2e-78
NHCLAHDE_01839 2.8e-100
NHCLAHDE_01840 9.9e-180
NHCLAHDE_01841 5.8e-83 S Fic/DOC family
NHCLAHDE_01842 7.4e-275 yjeM E Amino Acid
NHCLAHDE_01843 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHCLAHDE_01845 2.4e-49 EGP Major facilitator Superfamily
NHCLAHDE_01846 2.4e-45 EGP Major facilitator Superfamily
NHCLAHDE_01847 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
NHCLAHDE_01848 0.0 tetP J elongation factor G
NHCLAHDE_01849 3.5e-160 yvgN C Aldo keto reductase
NHCLAHDE_01850 2e-155 P CorA-like Mg2+ transporter protein
NHCLAHDE_01851 1.6e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NHCLAHDE_01852 4.9e-174 ABC-SBP S ABC transporter
NHCLAHDE_01853 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NHCLAHDE_01854 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
NHCLAHDE_01855 5.2e-248 G Major Facilitator
NHCLAHDE_01856 4.1e-18
NHCLAHDE_01857 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
NHCLAHDE_01858 1.4e-176 K AI-2E family transporter
NHCLAHDE_01859 8.6e-97 oppA E ABC transporter substrate-binding protein
NHCLAHDE_01860 1.2e-232 oppA E ABC transporter substrate-binding protein
NHCLAHDE_01861 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NHCLAHDE_01862 8.4e-74 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NHCLAHDE_01863 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NHCLAHDE_01865 2.6e-146 S Putative ABC-transporter type IV
NHCLAHDE_01866 1.7e-07 S LPXTG cell wall anchor motif

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)