ORF_ID e_value Gene_name EC_number CAZy COGs Description
MMMEGNCI_00002 6.1e-48 E Pfam:DUF955
MMMEGNCI_00003 1.7e-23 relB L Addiction module antitoxin, RelB DinJ family
MMMEGNCI_00004 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MMMEGNCI_00006 3.7e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MMMEGNCI_00008 1.1e-23 S CAAX protease self-immunity
MMMEGNCI_00010 4.1e-34
MMMEGNCI_00011 1e-66 doc S Fic/DOC family
MMMEGNCI_00013 9.4e-51 L An automated process has identified a potential problem with this gene model
MMMEGNCI_00014 7.9e-16 L An automated process has identified a potential problem with this gene model
MMMEGNCI_00016 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
MMMEGNCI_00017 9.7e-205 gatC G PTS system sugar-specific permease component
MMMEGNCI_00018 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MMMEGNCI_00019 3.5e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MMMEGNCI_00020 8.3e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MMMEGNCI_00021 2.4e-99 L An automated process has identified a potential problem with this gene model
MMMEGNCI_00022 3.3e-241 V N-6 DNA Methylase
MMMEGNCI_00023 3.8e-82 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
MMMEGNCI_00024 1.4e-52 EGP Sugar (and other) transporter
MMMEGNCI_00025 1e-104
MMMEGNCI_00026 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MMMEGNCI_00027 0.0 copA 3.6.3.54 P P-type ATPase
MMMEGNCI_00028 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MMMEGNCI_00029 4.9e-58 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MMMEGNCI_00030 2.4e-36
MMMEGNCI_00034 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MMMEGNCI_00035 7.5e-103 G Phosphoglycerate mutase family
MMMEGNCI_00036 1.2e-210 S Bacterial protein of unknown function (DUF871)
MMMEGNCI_00038 2.3e-43 ybhL S Belongs to the BI1 family
MMMEGNCI_00039 6.3e-33 S Domain of unknown function (DUF4767)
MMMEGNCI_00040 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MMMEGNCI_00041 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
MMMEGNCI_00042 3.2e-101 3.6.1.27 I Acid phosphatase homologues
MMMEGNCI_00043 7.3e-126 S Alpha/beta hydrolase family
MMMEGNCI_00044 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
MMMEGNCI_00045 4.4e-140 ypuA S Protein of unknown function (DUF1002)
MMMEGNCI_00046 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MMMEGNCI_00047 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
MMMEGNCI_00048 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMMEGNCI_00049 9.3e-86
MMMEGNCI_00050 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MMMEGNCI_00051 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MMMEGNCI_00052 1e-167 cvfB S S1 domain
MMMEGNCI_00053 2.9e-165 xerD D recombinase XerD
MMMEGNCI_00054 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MMMEGNCI_00055 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MMMEGNCI_00056 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MMMEGNCI_00057 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MMMEGNCI_00058 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MMMEGNCI_00059 2.7e-18 M Lysin motif
MMMEGNCI_00060 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MMMEGNCI_00061 1.4e-24 rpsA 1.17.7.4 J Ribosomal protein S1
MMMEGNCI_00062 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MMMEGNCI_00063 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MMMEGNCI_00064 1.4e-75 S Tetratricopeptide repeat protein
MMMEGNCI_00065 3.8e-99 S Tetratricopeptide repeat protein
MMMEGNCI_00066 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMMEGNCI_00067 6.9e-47 mdtG EGP Major facilitator Superfamily
MMMEGNCI_00068 1.7e-152 mdtG EGP Major facilitator Superfamily
MMMEGNCI_00069 1.3e-174
MMMEGNCI_00070 2.8e-47 lysM M LysM domain
MMMEGNCI_00071 0.0 pepN 3.4.11.2 E aminopeptidase
MMMEGNCI_00072 1.3e-250 dtpT U amino acid peptide transporter
MMMEGNCI_00073 1.2e-18 S Sugar efflux transporter for intercellular exchange
MMMEGNCI_00074 6.6e-70 XK27_02470 K LytTr DNA-binding domain
MMMEGNCI_00075 7.9e-92 liaI S membrane
MMMEGNCI_00076 4e-16
MMMEGNCI_00077 3.9e-186 S Putative peptidoglycan binding domain
MMMEGNCI_00078 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
MMMEGNCI_00079 9e-121
MMMEGNCI_00080 2e-35
MMMEGNCI_00082 2.5e-103 pncA Q Isochorismatase family
MMMEGNCI_00083 4.9e-118
MMMEGNCI_00086 6.6e-40
MMMEGNCI_00088 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MMMEGNCI_00089 3.5e-101 ylbE GM NAD(P)H-binding
MMMEGNCI_00090 7.6e-94 S VanZ like family
MMMEGNCI_00091 8.9e-133 yebC K Transcriptional regulatory protein
MMMEGNCI_00092 1.7e-179 comGA NU Type II IV secretion system protein
MMMEGNCI_00093 1.7e-171 comGB NU type II secretion system
MMMEGNCI_00094 3.1e-43 comGC U competence protein ComGC
MMMEGNCI_00095 2.3e-41
MMMEGNCI_00096 3.8e-77 comGF U Putative Competence protein ComGF
MMMEGNCI_00097 1.6e-21
MMMEGNCI_00098 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
MMMEGNCI_00099 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MMMEGNCI_00101 8.5e-151 L Belongs to the 'phage' integrase family
MMMEGNCI_00102 1e-08 S Pfam:DUF955
MMMEGNCI_00103 9.8e-16 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_00104 4e-22 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_00105 1e-25 K Helix-turn-helix domain
MMMEGNCI_00107 4.1e-09 S Arc-like DNA binding domain
MMMEGNCI_00109 4e-21 K Conserved phage C-terminus (Phg_2220_C)
MMMEGNCI_00110 1.5e-26 S Domain of unknown function (DUF771)
MMMEGNCI_00116 7.8e-34 S Phage derived protein Gp49-like (DUF891)
MMMEGNCI_00117 1e-33 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_00119 1.1e-188 L N-6 DNA Methylase
MMMEGNCI_00120 2.2e-26 S Type I restriction modification DNA specificity domain
MMMEGNCI_00121 3.7e-10 S Single-strand binding protein family
MMMEGNCI_00126 1.5e-12 S SLAP domain
MMMEGNCI_00128 1.4e-24 srtA 3.4.22.70 M sortase family
MMMEGNCI_00130 1.8e-41 M domain protein
MMMEGNCI_00131 7.2e-15 S SLAP domain
MMMEGNCI_00132 4.6e-31 M domain protein
MMMEGNCI_00136 4.1e-46 U TraM recognition site of TraD and TraG
MMMEGNCI_00137 6.8e-60 divIC D Septum formation initiator
MMMEGNCI_00138 1.8e-62 yabR J S1 RNA binding domain
MMMEGNCI_00139 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MMMEGNCI_00140 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MMMEGNCI_00141 2.2e-165 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MMMEGNCI_00142 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MMMEGNCI_00143 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MMMEGNCI_00144 1.4e-83 K FR47-like protein
MMMEGNCI_00145 1.4e-72 V ABC transporter, ATP-binding protein
MMMEGNCI_00146 7.6e-31 S ABC-2 family transporter protein
MMMEGNCI_00147 1.8e-21 S ABC-2 family transporter protein
MMMEGNCI_00148 2.1e-76 S ABC-2 family transporter protein
MMMEGNCI_00149 8.2e-230 pbuG S permease
MMMEGNCI_00150 8.2e-140 cof S haloacid dehalogenase-like hydrolase
MMMEGNCI_00151 9.4e-72
MMMEGNCI_00152 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MMMEGNCI_00153 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MMMEGNCI_00154 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MMMEGNCI_00155 1.1e-158 yeaE S Aldo/keto reductase family
MMMEGNCI_00156 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
MMMEGNCI_00157 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
MMMEGNCI_00158 1.3e-282 xylG 3.6.3.17 S ABC transporter
MMMEGNCI_00159 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
MMMEGNCI_00160 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
MMMEGNCI_00161 5.6e-95 V ABC-type multidrug transport system, ATPase and permease components
MMMEGNCI_00162 1.3e-157 V ABC-type multidrug transport system, ATPase and permease components
MMMEGNCI_00163 1.1e-141 yfeO P Voltage gated chloride channel
MMMEGNCI_00164 6.8e-184 5.3.3.2 C FMN-dependent dehydrogenase
MMMEGNCI_00165 1.2e-50
MMMEGNCI_00166 2.1e-42
MMMEGNCI_00167 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MMMEGNCI_00168 9.5e-297 ybeC E amino acid
MMMEGNCI_00169 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
MMMEGNCI_00170 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
MMMEGNCI_00171 2.5e-39 rpmE2 J Ribosomal protein L31
MMMEGNCI_00172 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MMMEGNCI_00173 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MMMEGNCI_00174 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MMMEGNCI_00175 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MMMEGNCI_00176 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
MMMEGNCI_00177 2.8e-119 3.6.1.55 F NUDIX domain
MMMEGNCI_00178 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
MMMEGNCI_00179 2.7e-83 S Protein of unknown function (DUF1211)
MMMEGNCI_00180 1.9e-21
MMMEGNCI_00181 1.7e-147
MMMEGNCI_00182 1.5e-169
MMMEGNCI_00183 2e-263 glnA 6.3.1.2 E glutamine synthetase
MMMEGNCI_00184 3e-221 ynbB 4.4.1.1 P aluminum resistance
MMMEGNCI_00185 1e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MMMEGNCI_00186 1.5e-65 yqhL P Rhodanese-like protein
MMMEGNCI_00187 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
MMMEGNCI_00188 3.1e-119 gluP 3.4.21.105 S Rhomboid family
MMMEGNCI_00189 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MMMEGNCI_00190 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MMMEGNCI_00191 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MMMEGNCI_00192 0.0 S membrane
MMMEGNCI_00193 8.8e-58 S Peptidase propeptide and YPEB domain
MMMEGNCI_00194 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MMMEGNCI_00195 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
MMMEGNCI_00196 7.1e-98 E GDSL-like Lipase/Acylhydrolase
MMMEGNCI_00197 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
MMMEGNCI_00198 1.6e-143 aatB ET ABC transporter substrate-binding protein
MMMEGNCI_00199 1e-105 glnQ 3.6.3.21 E ABC transporter
MMMEGNCI_00200 1.5e-107 glnP P ABC transporter permease
MMMEGNCI_00201 0.0 helD 3.6.4.12 L DNA helicase
MMMEGNCI_00202 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MMMEGNCI_00203 1.4e-126 pgm3 G Phosphoglycerate mutase family
MMMEGNCI_00204 2e-42 fryA 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MMMEGNCI_00205 5.3e-37 mngA 2.7.1.195, 2.7.1.202 G Psort location Cytoplasmic, score 9.98
MMMEGNCI_00206 2.7e-149 mngA 2.7.1.195, 2.7.1.202 U system, fructose-specific IIC component
MMMEGNCI_00207 5.5e-281 ybgG 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
MMMEGNCI_00208 1.4e-137 licR 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
MMMEGNCI_00209 0.0 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
MMMEGNCI_00210 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MMMEGNCI_00211 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MMMEGNCI_00212 9.7e-52 S Iron-sulfur cluster assembly protein
MMMEGNCI_00213 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MMMEGNCI_00214 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MMMEGNCI_00215 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MMMEGNCI_00216 3.1e-48 S Domain of unknown function (DUF4811)
MMMEGNCI_00217 1.4e-262 lmrB EGP Major facilitator Superfamily
MMMEGNCI_00218 4.2e-77 K MerR HTH family regulatory protein
MMMEGNCI_00219 3.1e-139 S Cysteine-rich secretory protein family
MMMEGNCI_00220 4.6e-274 ycaM E amino acid
MMMEGNCI_00221 2.8e-290
MMMEGNCI_00223 2.6e-189 cggR K Putative sugar-binding domain
MMMEGNCI_00224 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MMMEGNCI_00225 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MMMEGNCI_00226 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MMMEGNCI_00227 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
MMMEGNCI_00228 4.1e-36 ptp2 3.1.3.48 T Tyrosine phosphatase family
MMMEGNCI_00229 1.3e-30
MMMEGNCI_00230 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
MMMEGNCI_00231 3.7e-102 L Integrase
MMMEGNCI_00232 4.2e-92 S SNARE associated Golgi protein
MMMEGNCI_00233 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MMMEGNCI_00234 1.2e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MMMEGNCI_00235 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MMMEGNCI_00236 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
MMMEGNCI_00237 6.8e-110 yjbK S CYTH
MMMEGNCI_00238 4.6e-114 yjbH Q Thioredoxin
MMMEGNCI_00239 4e-13 coiA 3.6.4.12 S Competence protein
MMMEGNCI_00240 3.3e-132 coiA 3.6.4.12 S Competence protein
MMMEGNCI_00241 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MMMEGNCI_00242 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MMMEGNCI_00243 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MMMEGNCI_00244 8.5e-41 ptsH G phosphocarrier protein HPR
MMMEGNCI_00245 5.3e-26
MMMEGNCI_00246 8.8e-41 clcA P chloride
MMMEGNCI_00247 1.6e-60 clcA P chloride
MMMEGNCI_00248 4.7e-26 K FCD
MMMEGNCI_00249 2.5e-15
MMMEGNCI_00250 1.4e-200 L Transposase and inactivated derivatives, IS30 family
MMMEGNCI_00251 5.2e-08
MMMEGNCI_00252 3e-89 ntd 2.4.2.6 F Nucleoside
MMMEGNCI_00253 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MMMEGNCI_00254 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
MMMEGNCI_00255 8.8e-84 uspA T universal stress protein
MMMEGNCI_00257 3.4e-161 phnD P Phosphonate ABC transporter
MMMEGNCI_00258 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MMMEGNCI_00259 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MMMEGNCI_00260 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MMMEGNCI_00261 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
MMMEGNCI_00262 9e-98
MMMEGNCI_00263 4.9e-108 K LysR substrate binding domain
MMMEGNCI_00264 1e-20
MMMEGNCI_00265 2.3e-215 S Sterol carrier protein domain
MMMEGNCI_00266 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MMMEGNCI_00267 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
MMMEGNCI_00268 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MMMEGNCI_00269 8.8e-234 arcA 3.5.3.6 E Arginine
MMMEGNCI_00270 9e-137 lysR5 K LysR substrate binding domain
MMMEGNCI_00271 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
MMMEGNCI_00272 1e-48 S Metal binding domain of Ada
MMMEGNCI_00273 1.8e-163
MMMEGNCI_00274 7.8e-26 K Acetyltransferase (GNAT) domain
MMMEGNCI_00276 0.0 ydgH S MMPL family
MMMEGNCI_00277 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
MMMEGNCI_00278 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
MMMEGNCI_00279 1.8e-154 corA P CorA-like Mg2+ transporter protein
MMMEGNCI_00280 2.3e-240 G Bacterial extracellular solute-binding protein
MMMEGNCI_00281 1e-256 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
MMMEGNCI_00282 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
MMMEGNCI_00283 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
MMMEGNCI_00284 1.9e-203 malK P ATPases associated with a variety of cellular activities
MMMEGNCI_00285 1.3e-281 pipD E Dipeptidase
MMMEGNCI_00286 1.9e-158 endA F DNA RNA non-specific endonuclease
MMMEGNCI_00287 8e-182 dnaQ 2.7.7.7 L EXOIII
MMMEGNCI_00288 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MMMEGNCI_00289 3e-116 yviA S Protein of unknown function (DUF421)
MMMEGNCI_00290 1.1e-56 S Protein of unknown function (DUF3290)
MMMEGNCI_00293 2.4e-18 CO COG0526, thiol-disulfide isomerase and thioredoxins
MMMEGNCI_00296 2.1e-32 M Peptidase family M23
MMMEGNCI_00297 1.8e-159 trsE S COG0433 Predicted ATPase
MMMEGNCI_00298 8.4e-15
MMMEGNCI_00300 3.9e-32 I mechanosensitive ion channel activity
MMMEGNCI_00301 6.2e-87 U TraM recognition site of TraD and TraG
MMMEGNCI_00302 3.2e-19
MMMEGNCI_00304 1.1e-282 phoR 2.7.13.3 T Histidine kinase
MMMEGNCI_00305 9.5e-121 T Transcriptional regulatory protein, C terminal
MMMEGNCI_00306 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
MMMEGNCI_00307 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MMMEGNCI_00308 1.2e-152 pstA P Phosphate transport system permease protein PstA
MMMEGNCI_00309 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MMMEGNCI_00310 4.2e-145 pstS P Phosphate
MMMEGNCI_00311 1.3e-30
MMMEGNCI_00312 1.4e-191 oppA E ABC transporter, substratebinding protein
MMMEGNCI_00313 4.7e-275 ytgP S Polysaccharide biosynthesis protein
MMMEGNCI_00314 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MMMEGNCI_00315 1.1e-121 3.6.1.27 I Acid phosphatase homologues
MMMEGNCI_00316 2.8e-168 K LysR substrate binding domain
MMMEGNCI_00317 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MMMEGNCI_00318 6.2e-43 1.3.5.4 C FAD binding domain
MMMEGNCI_00319 1.1e-231 ndh 1.6.99.3 C NADH dehydrogenase
MMMEGNCI_00320 7.3e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MMMEGNCI_00321 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MMMEGNCI_00322 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MMMEGNCI_00323 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MMMEGNCI_00324 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MMMEGNCI_00325 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MMMEGNCI_00326 1.2e-227 cydA 1.10.3.14 C ubiquinol oxidase
MMMEGNCI_00327 2.2e-31 cydA 1.10.3.14 C ubiquinol oxidase
MMMEGNCI_00328 3.7e-130 ybbH_2 K rpiR family
MMMEGNCI_00329 3.4e-195 S Bacterial protein of unknown function (DUF871)
MMMEGNCI_00330 4.4e-48 2.7.1.208, 2.7.1.211 G phosphotransferase system
MMMEGNCI_00331 1.6e-157 2.7.1.208, 2.7.1.211 G phosphotransferase system
MMMEGNCI_00332 1.8e-119 S Putative esterase
MMMEGNCI_00333 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MMMEGNCI_00334 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
MMMEGNCI_00336 8.5e-260 qacA EGP Major facilitator Superfamily
MMMEGNCI_00337 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MMMEGNCI_00340 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
MMMEGNCI_00342 7.5e-231 pbuG S permease
MMMEGNCI_00343 2.5e-119 K helix_turn_helix, mercury resistance
MMMEGNCI_00344 3.3e-37
MMMEGNCI_00345 2.1e-111 S Fic/DOC family
MMMEGNCI_00346 1.7e-39 L Protein of unknown function (DUF3991)
MMMEGNCI_00347 6.3e-54 S COG0790 FOG TPR repeat, SEL1 subfamily
MMMEGNCI_00349 1.2e-79 K Acetyltransferase (GNAT) domain
MMMEGNCI_00350 2.7e-155 M Belongs to the glycosyl hydrolase 28 family
MMMEGNCI_00351 1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
MMMEGNCI_00352 6.5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MMMEGNCI_00353 1.5e-149 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MMMEGNCI_00354 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMMEGNCI_00355 3.5e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMMEGNCI_00356 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMMEGNCI_00357 1.4e-60 rplQ J Ribosomal protein L17
MMMEGNCI_00358 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MMMEGNCI_00359 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MMMEGNCI_00360 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MMMEGNCI_00361 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MMMEGNCI_00362 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MMMEGNCI_00363 1e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MMMEGNCI_00364 9e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MMMEGNCI_00365 2.6e-71 rplO J Binds to the 23S rRNA
MMMEGNCI_00366 2.3e-24 rpmD J Ribosomal protein L30
MMMEGNCI_00367 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MMMEGNCI_00368 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MMMEGNCI_00369 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MMMEGNCI_00370 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MMMEGNCI_00371 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MMMEGNCI_00372 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MMMEGNCI_00373 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MMMEGNCI_00374 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MMMEGNCI_00375 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MMMEGNCI_00376 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MMMEGNCI_00377 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MMMEGNCI_00378 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MMMEGNCI_00379 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MMMEGNCI_00380 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MMMEGNCI_00381 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MMMEGNCI_00382 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MMMEGNCI_00383 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
MMMEGNCI_00384 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MMMEGNCI_00385 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MMMEGNCI_00386 4.9e-282 L AAA domain
MMMEGNCI_00387 4.2e-61 V Abi-like protein
MMMEGNCI_00388 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MMMEGNCI_00419 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
MMMEGNCI_00420 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
MMMEGNCI_00421 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MMMEGNCI_00422 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MMMEGNCI_00423 1.7e-29 secG U Preprotein translocase
MMMEGNCI_00424 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MMMEGNCI_00425 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MMMEGNCI_00426 3.8e-105 vanZ V VanZ like family
MMMEGNCI_00427 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
MMMEGNCI_00428 3.8e-217 EGP Major facilitator Superfamily
MMMEGNCI_00429 3.9e-195 ampC V Beta-lactamase
MMMEGNCI_00432 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MMMEGNCI_00433 1.3e-113 tdk 2.7.1.21 F thymidine kinase
MMMEGNCI_00434 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MMMEGNCI_00435 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MMMEGNCI_00436 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MMMEGNCI_00437 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MMMEGNCI_00438 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
MMMEGNCI_00439 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MMMEGNCI_00440 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MMMEGNCI_00441 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MMMEGNCI_00442 2.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MMMEGNCI_00443 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MMMEGNCI_00444 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MMMEGNCI_00445 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MMMEGNCI_00446 2e-30 ywzB S Protein of unknown function (DUF1146)
MMMEGNCI_00447 4.7e-177 mbl D Cell shape determining protein MreB Mrl
MMMEGNCI_00448 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MMMEGNCI_00449 3.3e-33 S Protein of unknown function (DUF2969)
MMMEGNCI_00450 4.7e-216 rodA D Belongs to the SEDS family
MMMEGNCI_00451 1.8e-78 usp6 T universal stress protein
MMMEGNCI_00452 8.4e-39
MMMEGNCI_00453 2.2e-238 rarA L recombination factor protein RarA
MMMEGNCI_00454 1.3e-84 yueI S Protein of unknown function (DUF1694)
MMMEGNCI_00455 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MMMEGNCI_00456 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MMMEGNCI_00457 7.4e-214 iscS2 2.8.1.7 E Aminotransferase class V
MMMEGNCI_00458 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MMMEGNCI_00459 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MMMEGNCI_00460 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MMMEGNCI_00461 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MMMEGNCI_00462 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
MMMEGNCI_00463 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MMMEGNCI_00464 1.5e-94 S Protein of unknown function (DUF3990)
MMMEGNCI_00465 6.5e-44
MMMEGNCI_00467 0.0 3.6.3.8 P P-type ATPase
MMMEGNCI_00468 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
MMMEGNCI_00469 2.5e-52
MMMEGNCI_00470 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MMMEGNCI_00471 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MMMEGNCI_00472 5.7e-126 S Haloacid dehalogenase-like hydrolase
MMMEGNCI_00473 2.3e-108 radC L DNA repair protein
MMMEGNCI_00474 2.4e-176 mreB D cell shape determining protein MreB
MMMEGNCI_00475 2e-147 mreC M Involved in formation and maintenance of cell shape
MMMEGNCI_00476 2.7e-94 mreD
MMMEGNCI_00478 6.4e-54 S Protein of unknown function (DUF3397)
MMMEGNCI_00479 6.3e-78 mraZ K Belongs to the MraZ family
MMMEGNCI_00480 2.1e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MMMEGNCI_00481 1.8e-54 ftsL D Cell division protein FtsL
MMMEGNCI_00482 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MMMEGNCI_00483 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MMMEGNCI_00484 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MMMEGNCI_00485 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MMMEGNCI_00486 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MMMEGNCI_00487 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MMMEGNCI_00488 5e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MMMEGNCI_00489 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MMMEGNCI_00490 1.7e-45 yggT S YGGT family
MMMEGNCI_00491 5.7e-149 ylmH S S4 domain protein
MMMEGNCI_00492 2.8e-74 gpsB D DivIVA domain protein
MMMEGNCI_00493 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MMMEGNCI_00494 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
MMMEGNCI_00495 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MMMEGNCI_00496 6.7e-37
MMMEGNCI_00497 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MMMEGNCI_00498 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
MMMEGNCI_00499 5.4e-56 XK27_04120 S Putative amino acid metabolism
MMMEGNCI_00500 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MMMEGNCI_00501 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MMMEGNCI_00502 8.3e-106 S Repeat protein
MMMEGNCI_00503 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MMMEGNCI_00504 1.6e-294 L Nuclease-related domain
MMMEGNCI_00505 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MMMEGNCI_00506 1.5e-102 GM NmrA-like family
MMMEGNCI_00507 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MMMEGNCI_00508 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MMMEGNCI_00509 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MMMEGNCI_00510 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MMMEGNCI_00511 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MMMEGNCI_00512 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MMMEGNCI_00513 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MMMEGNCI_00514 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MMMEGNCI_00515 3.7e-250 lctP C L-lactate permease
MMMEGNCI_00516 3.1e-148 glcU U sugar transport
MMMEGNCI_00517 7.1e-46
MMMEGNCI_00518 2.9e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MMMEGNCI_00519 9.6e-138 2.4.2.3 F Phosphorylase superfamily
MMMEGNCI_00520 1.5e-143 2.4.2.3 F Phosphorylase superfamily
MMMEGNCI_00521 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
MMMEGNCI_00522 0.0 L Plasmid pRiA4b ORF-3-like protein
MMMEGNCI_00523 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
MMMEGNCI_00524 3.4e-79
MMMEGNCI_00525 1e-242 cpdA S Calcineurin-like phosphoesterase
MMMEGNCI_00526 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MMMEGNCI_00527 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MMMEGNCI_00528 1e-107 ypsA S Belongs to the UPF0398 family
MMMEGNCI_00529 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MMMEGNCI_00530 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MMMEGNCI_00531 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MMMEGNCI_00532 1.3e-114 dnaD L DnaD domain protein
MMMEGNCI_00533 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MMMEGNCI_00534 9.2e-89 ypmB S Protein conserved in bacteria
MMMEGNCI_00535 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MMMEGNCI_00536 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MMMEGNCI_00537 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MMMEGNCI_00538 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
MMMEGNCI_00539 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MMMEGNCI_00540 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MMMEGNCI_00541 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MMMEGNCI_00542 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
MMMEGNCI_00543 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
MMMEGNCI_00544 9.7e-169
MMMEGNCI_00545 6.3e-142
MMMEGNCI_00546 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MMMEGNCI_00547 1.4e-26
MMMEGNCI_00548 2.1e-143
MMMEGNCI_00549 5.1e-137
MMMEGNCI_00550 4.5e-141
MMMEGNCI_00551 9.6e-124 skfE V ATPases associated with a variety of cellular activities
MMMEGNCI_00552 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
MMMEGNCI_00553 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MMMEGNCI_00554 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MMMEGNCI_00555 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
MMMEGNCI_00556 4.8e-81 mutT 3.6.1.55 F NUDIX domain
MMMEGNCI_00557 1.4e-127 S Peptidase family M23
MMMEGNCI_00558 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MMMEGNCI_00559 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MMMEGNCI_00560 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MMMEGNCI_00561 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MMMEGNCI_00562 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
MMMEGNCI_00563 6.2e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MMMEGNCI_00564 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MMMEGNCI_00565 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
MMMEGNCI_00566 3.5e-71 yqeY S YqeY-like protein
MMMEGNCI_00567 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MMMEGNCI_00568 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MMMEGNCI_00569 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
MMMEGNCI_00570 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MMMEGNCI_00571 0.0 uup S ABC transporter, ATP-binding protein
MMMEGNCI_00572 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MMMEGNCI_00573 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MMMEGNCI_00574 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MMMEGNCI_00575 7.7e-22
MMMEGNCI_00576 9.3e-64 L PFAM IS66 Orf2 family protein
MMMEGNCI_00577 8.7e-34 S Transposase C of IS166 homeodomain
MMMEGNCI_00578 1.1e-187 L Transposase IS66 family
MMMEGNCI_00579 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MMMEGNCI_00580 6.7e-56 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MMMEGNCI_00581 2.2e-15 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MMMEGNCI_00582 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MMMEGNCI_00583 2.2e-85 S ECF transporter, substrate-specific component
MMMEGNCI_00584 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
MMMEGNCI_00585 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MMMEGNCI_00586 1.8e-59 yabA L Involved in initiation control of chromosome replication
MMMEGNCI_00587 1.5e-155 holB 2.7.7.7 L DNA polymerase III
MMMEGNCI_00588 8.9e-53 yaaQ S Cyclic-di-AMP receptor
MMMEGNCI_00589 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MMMEGNCI_00590 1.1e-34 S Protein of unknown function (DUF2508)
MMMEGNCI_00591 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MMMEGNCI_00592 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MMMEGNCI_00593 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MMMEGNCI_00594 5.7e-106 2.4.1.58 GT8 M family 8
MMMEGNCI_00595 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MMMEGNCI_00596 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MMMEGNCI_00597 9e-26
MMMEGNCI_00598 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
MMMEGNCI_00599 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
MMMEGNCI_00600 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MMMEGNCI_00601 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MMMEGNCI_00602 1.5e-11 GT2,GT4 M family 8
MMMEGNCI_00603 2.8e-90 L An automated process has identified a potential problem with this gene model
MMMEGNCI_00604 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
MMMEGNCI_00605 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MMMEGNCI_00606 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MMMEGNCI_00607 6.5e-154 pstA P Phosphate transport system permease protein PstA
MMMEGNCI_00608 2.4e-17 S CAAX protease self-immunity
MMMEGNCI_00609 1.4e-22 S CAAX protease self-immunity
MMMEGNCI_00610 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_00612 1.6e-96 ybaT E Amino acid permease
MMMEGNCI_00613 7e-87 gtcA S Teichoic acid glycosylation protein
MMMEGNCI_00614 4.1e-80 fld C Flavodoxin
MMMEGNCI_00615 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
MMMEGNCI_00616 3.6e-163 yihY S Belongs to the UPF0761 family
MMMEGNCI_00617 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MMMEGNCI_00618 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MMMEGNCI_00619 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MMMEGNCI_00620 9.1e-54 papP P ABC transporter, permease protein
MMMEGNCI_00621 5.3e-116 P ABC transporter permease
MMMEGNCI_00622 1.5e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MMMEGNCI_00623 1e-156 cjaA ET ABC transporter substrate-binding protein
MMMEGNCI_00624 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MMMEGNCI_00625 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MMMEGNCI_00626 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MMMEGNCI_00627 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
MMMEGNCI_00628 7.1e-158 metQ1 P Belongs to the nlpA lipoprotein family
MMMEGNCI_00629 1.9e-25
MMMEGNCI_00630 0.0 mco Q Multicopper oxidase
MMMEGNCI_00631 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
MMMEGNCI_00632 0.0 oppA E ABC transporter
MMMEGNCI_00633 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
MMMEGNCI_00634 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
MMMEGNCI_00635 1e-137 S Protein of unknown function (DUF3100)
MMMEGNCI_00636 9.7e-83 S An automated process has identified a potential problem with this gene model
MMMEGNCI_00637 4.4e-103 K Putative DNA-binding domain
MMMEGNCI_00638 9.3e-35
MMMEGNCI_00639 2e-157 S reductase
MMMEGNCI_00640 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
MMMEGNCI_00641 1.6e-15 L hmm pf00665
MMMEGNCI_00642 2.9e-15 M LysM domain protein
MMMEGNCI_00643 3.8e-48 M LysM domain protein
MMMEGNCI_00644 1.4e-86 C Aldo keto reductase
MMMEGNCI_00645 8.3e-181 lacX 5.1.3.3 G Aldose 1-epimerase
MMMEGNCI_00646 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MMMEGNCI_00647 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MMMEGNCI_00648 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
MMMEGNCI_00649 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MMMEGNCI_00650 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MMMEGNCI_00651 5.8e-152 dprA LU DNA protecting protein DprA
MMMEGNCI_00652 1.7e-131 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MMMEGNCI_00653 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MMMEGNCI_00654 1.9e-94 yjcE P Sodium proton antiporter
MMMEGNCI_00655 1.5e-40 yjcE P Sodium proton antiporter
MMMEGNCI_00656 1.1e-66 yjcE P NhaP-type Na H and K H
MMMEGNCI_00657 7.1e-36 yozE S Belongs to the UPF0346 family
MMMEGNCI_00658 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
MMMEGNCI_00659 1.2e-107 hlyIII S protein, hemolysin III
MMMEGNCI_00660 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MMMEGNCI_00661 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMMEGNCI_00662 1.6e-85 3.4.21.96 S SLAP domain
MMMEGNCI_00663 8.4e-128 yagE E Amino acid permease
MMMEGNCI_00664 9.7e-65 yagE E amino acid
MMMEGNCI_00665 3.4e-75 S cog cog0433
MMMEGNCI_00666 1.9e-110 F DNA/RNA non-specific endonuclease
MMMEGNCI_00667 2.7e-34 S YSIRK type signal peptide
MMMEGNCI_00669 5.5e-53
MMMEGNCI_00670 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MMMEGNCI_00671 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MMMEGNCI_00672 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MMMEGNCI_00673 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MMMEGNCI_00674 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
MMMEGNCI_00675 0.0 FbpA K Fibronectin-binding protein
MMMEGNCI_00676 1.1e-66
MMMEGNCI_00677 1.3e-159 degV S EDD domain protein, DegV family
MMMEGNCI_00678 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MMMEGNCI_00679 2.1e-13 sprD D Domain of Unknown Function (DUF1542)
MMMEGNCI_00680 1.8e-84 scrR K Periplasmic binding protein domain
MMMEGNCI_00681 1.5e-141 msmE G Bacterial extracellular solute-binding protein
MMMEGNCI_00682 5e-160 scrR K Periplasmic binding protein domain
MMMEGNCI_00683 5.5e-36
MMMEGNCI_00684 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMMEGNCI_00685 3.5e-70 S Domain of unknown function (DUF3284)
MMMEGNCI_00686 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MMMEGNCI_00687 3.7e-131 gmuR K UTRA
MMMEGNCI_00688 3.7e-60 3.6.1.55 F NUDIX domain
MMMEGNCI_00689 1e-79 S AAA domain
MMMEGNCI_00690 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
MMMEGNCI_00691 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MMMEGNCI_00692 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MMMEGNCI_00693 6.7e-98 M ErfK YbiS YcfS YnhG
MMMEGNCI_00694 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MMMEGNCI_00695 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MMMEGNCI_00697 4.7e-46 pspC KT PspC domain
MMMEGNCI_00698 3.3e-237 L COG2963 Transposase and inactivated derivatives
MMMEGNCI_00699 8e-225 pbuG S permease
MMMEGNCI_00700 9.7e-146 S haloacid dehalogenase-like hydrolase
MMMEGNCI_00701 2e-225 S cog cog1373
MMMEGNCI_00702 6.1e-61 K Transcriptional regulator
MMMEGNCI_00703 1.3e-94 K Transcriptional regulator
MMMEGNCI_00704 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MMMEGNCI_00705 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MMMEGNCI_00706 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
MMMEGNCI_00707 2.2e-142 S Belongs to the UPF0246 family
MMMEGNCI_00708 2e-140 aroD S Alpha/beta hydrolase family
MMMEGNCI_00709 3.5e-111 G phosphoglycerate mutase
MMMEGNCI_00710 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
MMMEGNCI_00711 3.3e-176 hrtB V ABC transporter permease
MMMEGNCI_00712 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MMMEGNCI_00713 1.3e-273 pipD E Dipeptidase
MMMEGNCI_00714 2.4e-10 L Psort location Cytoplasmic, score
MMMEGNCI_00715 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MMMEGNCI_00716 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MMMEGNCI_00717 1.2e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MMMEGNCI_00718 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MMMEGNCI_00719 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MMMEGNCI_00720 6.3e-120 lsa S ABC transporter
MMMEGNCI_00721 1.3e-51
MMMEGNCI_00722 2.7e-57
MMMEGNCI_00723 1.6e-11
MMMEGNCI_00724 8.1e-126 S PAS domain
MMMEGNCI_00725 3.5e-241 S response to antibiotic
MMMEGNCI_00726 4.9e-125
MMMEGNCI_00727 0.0 3.6.3.8 P P-type ATPase
MMMEGNCI_00728 8.7e-66 2.7.1.191 G PTS system fructose IIA component
MMMEGNCI_00729 4.4e-43
MMMEGNCI_00730 5.9e-09
MMMEGNCI_00731 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
MMMEGNCI_00732 2.2e-134 glvR K Helix-turn-helix domain, rpiR family
MMMEGNCI_00733 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
MMMEGNCI_00734 3.8e-115 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MMMEGNCI_00735 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MMMEGNCI_00736 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
MMMEGNCI_00737 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
MMMEGNCI_00738 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
MMMEGNCI_00739 3.1e-240 oppA E ABC transporter substrate-binding protein
MMMEGNCI_00740 2.1e-308 oppA E ABC transporter substrate-binding protein
MMMEGNCI_00741 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MMMEGNCI_00742 0.0 smc D Required for chromosome condensation and partitioning
MMMEGNCI_00743 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MMMEGNCI_00744 2.5e-288 pipD E Dipeptidase
MMMEGNCI_00746 3.4e-23
MMMEGNCI_00747 4.1e-133 cysA V ABC transporter, ATP-binding protein
MMMEGNCI_00748 0.0 V FtsX-like permease family
MMMEGNCI_00749 2.7e-258 yfnA E amino acid
MMMEGNCI_00750 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MMMEGNCI_00751 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MMMEGNCI_00752 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MMMEGNCI_00753 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MMMEGNCI_00754 3.6e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MMMEGNCI_00755 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MMMEGNCI_00756 4.6e-213 S SLAP domain
MMMEGNCI_00757 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
MMMEGNCI_00758 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
MMMEGNCI_00759 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MMMEGNCI_00760 3e-38 ynzC S UPF0291 protein
MMMEGNCI_00761 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
MMMEGNCI_00762 0.0 mdlA V ABC transporter
MMMEGNCI_00763 0.0 mdlB V ABC transporter
MMMEGNCI_00764 0.0 pepO 3.4.24.71 O Peptidase family M13
MMMEGNCI_00765 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MMMEGNCI_00766 2.9e-116 plsC 2.3.1.51 I Acyltransferase
MMMEGNCI_00767 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
MMMEGNCI_00768 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
MMMEGNCI_00769 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MMMEGNCI_00770 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MMMEGNCI_00771 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MMMEGNCI_00772 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MMMEGNCI_00773 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
MMMEGNCI_00774 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MMMEGNCI_00775 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MMMEGNCI_00776 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MMMEGNCI_00777 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
MMMEGNCI_00778 1.4e-196 nusA K Participates in both transcription termination and antitermination
MMMEGNCI_00779 8.8e-47 ylxR K Protein of unknown function (DUF448)
MMMEGNCI_00780 3.2e-47 rplGA J ribosomal protein
MMMEGNCI_00781 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MMMEGNCI_00782 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MMMEGNCI_00783 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MMMEGNCI_00784 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MMMEGNCI_00785 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MMMEGNCI_00786 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MMMEGNCI_00787 0.0 dnaK O Heat shock 70 kDa protein
MMMEGNCI_00788 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MMMEGNCI_00789 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MMMEGNCI_00790 1.5e-102 srtA 3.4.22.70 M sortase family
MMMEGNCI_00791 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MMMEGNCI_00792 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MMMEGNCI_00793 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MMMEGNCI_00794 1.8e-104 3.2.2.20 K acetyltransferase
MMMEGNCI_00796 4.3e-226 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMMEGNCI_00797 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
MMMEGNCI_00798 4.1e-21 K Helix-turn-helix domain, rpiR family
MMMEGNCI_00799 2e-72 K Helix-turn-helix domain, rpiR family
MMMEGNCI_00800 3.4e-129 S (CBS) domain
MMMEGNCI_00801 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MMMEGNCI_00802 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MMMEGNCI_00803 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MMMEGNCI_00804 7.4e-40 yabO J S4 domain protein
MMMEGNCI_00805 2.6e-162 pstC P probably responsible for the translocation of the substrate across the membrane
MMMEGNCI_00806 2.8e-157 pstS P Phosphate
MMMEGNCI_00807 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MMMEGNCI_00808 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MMMEGNCI_00809 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
MMMEGNCI_00810 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MMMEGNCI_00811 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MMMEGNCI_00812 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MMMEGNCI_00813 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MMMEGNCI_00814 1.4e-190 I transferase activity, transferring acyl groups other than amino-acyl groups
MMMEGNCI_00815 5.6e-179 S PFAM Archaeal ATPase
MMMEGNCI_00816 3.1e-73 S cog cog1373
MMMEGNCI_00817 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MMMEGNCI_00818 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MMMEGNCI_00819 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MMMEGNCI_00820 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MMMEGNCI_00821 2.6e-103 lacS G Transporter
MMMEGNCI_00822 8.7e-57 lacS G Transporter
MMMEGNCI_00823 1.1e-137 lacS G Transporter
MMMEGNCI_00824 2.1e-164 lacR K Transcriptional regulator
MMMEGNCI_00825 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MMMEGNCI_00826 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MMMEGNCI_00827 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MMMEGNCI_00828 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MMMEGNCI_00829 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
MMMEGNCI_00830 2e-106 K Transcriptional regulator, AbiEi antitoxin
MMMEGNCI_00831 2.3e-187 K Periplasmic binding protein-like domain
MMMEGNCI_00832 3.6e-39 C FMN_bind
MMMEGNCI_00833 1.5e-81
MMMEGNCI_00834 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
MMMEGNCI_00835 2e-85 alkD L DNA alkylation repair enzyme
MMMEGNCI_00836 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MMMEGNCI_00837 6.4e-128 K UTRA domain
MMMEGNCI_00838 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MMMEGNCI_00839 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MMMEGNCI_00840 4.2e-63 lmrB EGP Major facilitator Superfamily
MMMEGNCI_00841 2.9e-122 rbtT P Major Facilitator Superfamily
MMMEGNCI_00842 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
MMMEGNCI_00843 2.5e-86 K GNAT family
MMMEGNCI_00844 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MMMEGNCI_00846 4.3e-36
MMMEGNCI_00847 8.2e-288 P ABC transporter
MMMEGNCI_00848 1.7e-34
MMMEGNCI_00849 1.2e-94 sigH K Belongs to the sigma-70 factor family
MMMEGNCI_00850 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MMMEGNCI_00851 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MMMEGNCI_00852 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MMMEGNCI_00853 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MMMEGNCI_00854 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MMMEGNCI_00855 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MMMEGNCI_00856 4.1e-52
MMMEGNCI_00857 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
MMMEGNCI_00858 8.1e-43
MMMEGNCI_00859 2.4e-183 S AAA domain
MMMEGNCI_00860 1.7e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MMMEGNCI_00861 1.4e-23
MMMEGNCI_00862 6.6e-162 czcD P cation diffusion facilitator family transporter
MMMEGNCI_00863 2.2e-125 gpmB G Belongs to the phosphoglycerate mutase family
MMMEGNCI_00864 1.1e-133 S membrane transporter protein
MMMEGNCI_00865 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MMMEGNCI_00866 2.6e-106 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MMMEGNCI_00867 1.1e-98 L Helix-turn-helix domain
MMMEGNCI_00868 1.3e-160 L hmm pf00665
MMMEGNCI_00869 5.8e-211 M Glycosyl hydrolases family 25
MMMEGNCI_00870 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
MMMEGNCI_00871 4.1e-67
MMMEGNCI_00872 5.4e-203 xerS L Belongs to the 'phage' integrase family
MMMEGNCI_00873 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MMMEGNCI_00874 0.0 dnaE 2.7.7.7 L DNA polymerase
MMMEGNCI_00875 2.3e-23 S Protein of unknown function (DUF2929)
MMMEGNCI_00876 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MMMEGNCI_00877 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MMMEGNCI_00878 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
MMMEGNCI_00879 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MMMEGNCI_00880 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MMMEGNCI_00881 2.2e-292 I Acyltransferase
MMMEGNCI_00882 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MMMEGNCI_00883 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MMMEGNCI_00884 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
MMMEGNCI_00885 1.1e-243 yfnA E Amino Acid
MMMEGNCI_00886 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMMEGNCI_00887 1.3e-148 yxeH S hydrolase
MMMEGNCI_00888 2.7e-32 S reductase
MMMEGNCI_00889 4.4e-39 S reductase
MMMEGNCI_00890 4.8e-34 S reductase
MMMEGNCI_00891 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MMMEGNCI_00892 6.1e-216 3.6.3.6 P Cation transporter/ATPase, N-terminus
MMMEGNCI_00893 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
MMMEGNCI_00894 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
MMMEGNCI_00895 4.5e-68 S Domain of unknown function (DUF1934)
MMMEGNCI_00896 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MMMEGNCI_00897 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MMMEGNCI_00898 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MMMEGNCI_00899 2.1e-80 K acetyltransferase
MMMEGNCI_00900 1.3e-47 adk 2.7.4.3 F AAA domain
MMMEGNCI_00901 4.4e-285 pipD E Dipeptidase
MMMEGNCI_00902 2.5e-152 msmR K AraC-like ligand binding domain
MMMEGNCI_00903 1.4e-226 pbuX F xanthine permease
MMMEGNCI_00904 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MMMEGNCI_00905 2.4e-43 K Helix-turn-helix
MMMEGNCI_00906 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MMMEGNCI_00908 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MMMEGNCI_00909 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
MMMEGNCI_00910 2.3e-184 3.2.1.18 GH33 M Rib/alpha-like repeat
MMMEGNCI_00912 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
MMMEGNCI_00913 1e-95
MMMEGNCI_00914 8.9e-268 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MMMEGNCI_00915 1.2e-127 K LytTr DNA-binding domain
MMMEGNCI_00916 4.4e-138 2.7.13.3 T GHKL domain
MMMEGNCI_00917 1.2e-16
MMMEGNCI_00918 2.1e-255 S Archaea bacterial proteins of unknown function
MMMEGNCI_00919 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MMMEGNCI_00920 1.1e-269 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
MMMEGNCI_00921 1e-24
MMMEGNCI_00922 9.5e-26
MMMEGNCI_00923 2.5e-33
MMMEGNCI_00924 1.4e-53 S Enterocin A Immunity
MMMEGNCI_00925 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MMMEGNCI_00926 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MMMEGNCI_00927 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
MMMEGNCI_00928 9.6e-121 K response regulator
MMMEGNCI_00930 0.0 V ABC transporter
MMMEGNCI_00931 4.2e-144 V ABC transporter, ATP-binding protein
MMMEGNCI_00932 1.2e-145 V ABC transporter, ATP-binding protein
MMMEGNCI_00933 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
MMMEGNCI_00934 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MMMEGNCI_00935 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
MMMEGNCI_00936 1.5e-153 spo0J K Belongs to the ParB family
MMMEGNCI_00937 3.4e-138 soj D Sporulation initiation inhibitor
MMMEGNCI_00938 5e-148 noc K Belongs to the ParB family
MMMEGNCI_00939 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MMMEGNCI_00940 4.4e-172 S Domain of unknown function (DUF389)
MMMEGNCI_00941 6e-86
MMMEGNCI_00942 5.9e-68 S Protein of unknown function (DUF3021)
MMMEGNCI_00943 9.5e-140 V ABC transporter
MMMEGNCI_00944 3.3e-106 S domain protein
MMMEGNCI_00945 8.4e-265 S Fibronectin type III domain
MMMEGNCI_00946 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MMMEGNCI_00947 1.1e-114 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MMMEGNCI_00948 0.0 L PLD-like domain
MMMEGNCI_00949 4.8e-42 S SnoaL-like domain
MMMEGNCI_00950 5.4e-53 hipB K sequence-specific DNA binding
MMMEGNCI_00951 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
MMMEGNCI_00952 3.4e-27
MMMEGNCI_00953 3.3e-183 scrR K helix_turn _helix lactose operon repressor
MMMEGNCI_00954 3.7e-295 scrB 3.2.1.26 GH32 G invertase
MMMEGNCI_00955 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
MMMEGNCI_00956 2.3e-181 M CHAP domain
MMMEGNCI_00957 3.5e-75
MMMEGNCI_00958 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MMMEGNCI_00959 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MMMEGNCI_00960 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MMMEGNCI_00961 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MMMEGNCI_00962 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MMMEGNCI_00963 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MMMEGNCI_00964 9.6e-41 yajC U Preprotein translocase
MMMEGNCI_00965 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MMMEGNCI_00966 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MMMEGNCI_00967 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MMMEGNCI_00968 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MMMEGNCI_00969 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MMMEGNCI_00970 2e-42 yrzL S Belongs to the UPF0297 family
MMMEGNCI_00971 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MMMEGNCI_00972 1.1e-50 yrzB S Belongs to the UPF0473 family
MMMEGNCI_00973 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MMMEGNCI_00974 3.5e-54 trxA O Belongs to the thioredoxin family
MMMEGNCI_00975 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MMMEGNCI_00976 1.1e-71 yslB S Protein of unknown function (DUF2507)
MMMEGNCI_00977 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MMMEGNCI_00978 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MMMEGNCI_00979 7.7e-30 ropB K Helix-turn-helix domain
MMMEGNCI_00980 1.7e-153 ydjP I Alpha/beta hydrolase family
MMMEGNCI_00981 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MMMEGNCI_00982 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
MMMEGNCI_00983 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MMMEGNCI_00984 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MMMEGNCI_00985 9.3e-72 yeaL S Protein of unknown function (DUF441)
MMMEGNCI_00986 3.5e-21
MMMEGNCI_00987 3.6e-146 cbiQ P cobalt transport
MMMEGNCI_00988 0.0 ykoD P ABC transporter, ATP-binding protein
MMMEGNCI_00989 1.5e-95 S UPF0397 protein
MMMEGNCI_00990 2.9e-66 S Domain of unknown function DUF1828
MMMEGNCI_00991 5.5e-09
MMMEGNCI_00992 1.5e-50
MMMEGNCI_00993 2.6e-177 citR K Putative sugar-binding domain
MMMEGNCI_00994 7.2e-248 yjjP S Putative threonine/serine exporter
MMMEGNCI_00996 5.9e-37 M domain protein
MMMEGNCI_00997 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MMMEGNCI_00998 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
MMMEGNCI_00999 8.5e-60
MMMEGNCI_01000 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MMMEGNCI_01001 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MMMEGNCI_01002 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MMMEGNCI_01003 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MMMEGNCI_01004 1.2e-222 patA 2.6.1.1 E Aminotransferase
MMMEGNCI_01005 2.9e-277 V ABC transporter transmembrane region
MMMEGNCI_01006 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MMMEGNCI_01007 3.1e-130 T Transcriptional regulatory protein, C terminal
MMMEGNCI_01008 5.2e-187 T GHKL domain
MMMEGNCI_01009 3.4e-76 S Peptidase propeptide and YPEB domain
MMMEGNCI_01010 2.5e-72 S Peptidase propeptide and YPEB domain
MMMEGNCI_01011 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MMMEGNCI_01012 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
MMMEGNCI_01013 7e-68 V ABC transporter transmembrane region
MMMEGNCI_01014 9e-161 V ABC transporter transmembrane region
MMMEGNCI_01015 2.3e-309 oppA3 E ABC transporter, substratebinding protein
MMMEGNCI_01016 2.4e-60 ypaA S Protein of unknown function (DUF1304)
MMMEGNCI_01017 2.1e-28 S Peptidase propeptide and YPEB domain
MMMEGNCI_01018 4.4e-239 L transposase, IS605 OrfB family
MMMEGNCI_01019 2e-310 E Amino acid permease
MMMEGNCI_01021 3e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MMMEGNCI_01022 2.2e-90 2.7.7.65 T GGDEF domain
MMMEGNCI_01023 8.2e-36
MMMEGNCI_01024 8.9e-112 ica2 GT2 M Glycosyl transferase family group 2
MMMEGNCI_01025 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MMMEGNCI_01026 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MMMEGNCI_01027 1e-149 D Alpha beta
MMMEGNCI_01028 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MMMEGNCI_01029 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
MMMEGNCI_01030 8.3e-143 licT K CAT RNA binding domain
MMMEGNCI_01031 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MMMEGNCI_01032 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MMMEGNCI_01033 1.6e-118
MMMEGNCI_01034 1.8e-75 K Penicillinase repressor
MMMEGNCI_01035 3.2e-147 S hydrolase
MMMEGNCI_01036 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MMMEGNCI_01037 2e-172 ybbR S YbbR-like protein
MMMEGNCI_01038 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MMMEGNCI_01039 7.3e-208 potD P ABC transporter
MMMEGNCI_01040 4.8e-127 potC P ABC transporter permease
MMMEGNCI_01041 1.3e-129 potB P ABC transporter permease
MMMEGNCI_01042 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MMMEGNCI_01043 2e-163 murB 1.3.1.98 M Cell wall formation
MMMEGNCI_01044 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
MMMEGNCI_01045 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MMMEGNCI_01046 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MMMEGNCI_01047 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MMMEGNCI_01048 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
MMMEGNCI_01049 1.2e-94
MMMEGNCI_01050 8.3e-24 papP P ABC transporter, permease protein
MMMEGNCI_01052 4.5e-58 yodB K Transcriptional regulator, HxlR family
MMMEGNCI_01053 2.2e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MMMEGNCI_01054 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MMMEGNCI_01055 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MMMEGNCI_01056 6.3e-82 S Aminoacyl-tRNA editing domain
MMMEGNCI_01057 6.1e-224 S SLAP domain
MMMEGNCI_01058 1.5e-97 S CAAX protease self-immunity
MMMEGNCI_01059 1e-12
MMMEGNCI_01060 1.3e-277 arlS 2.7.13.3 T Histidine kinase
MMMEGNCI_01061 1.2e-126 K response regulator
MMMEGNCI_01062 4.7e-97 yceD S Uncharacterized ACR, COG1399
MMMEGNCI_01063 4.6e-216 ylbM S Belongs to the UPF0348 family
MMMEGNCI_01064 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MMMEGNCI_01065 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MMMEGNCI_01066 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MMMEGNCI_01067 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
MMMEGNCI_01068 4.2e-84 yqeG S HAD phosphatase, family IIIA
MMMEGNCI_01069 4.3e-198 tnpB L Putative transposase DNA-binding domain
MMMEGNCI_01070 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MMMEGNCI_01071 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MMMEGNCI_01072 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MMMEGNCI_01073 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MMMEGNCI_01074 2.7e-36 yyaR K Acetyltransferase (GNAT) domain
MMMEGNCI_01075 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MMMEGNCI_01076 3.2e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MMMEGNCI_01077 4.5e-39 veg S Biofilm formation stimulator VEG
MMMEGNCI_01078 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MMMEGNCI_01079 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MMMEGNCI_01080 1e-147 tatD L hydrolase, TatD family
MMMEGNCI_01081 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MMMEGNCI_01082 1.3e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MMMEGNCI_01083 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MMMEGNCI_01084 2e-103 S TPM domain
MMMEGNCI_01085 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
MMMEGNCI_01086 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MMMEGNCI_01087 1.2e-111 E Belongs to the SOS response-associated peptidase family
MMMEGNCI_01089 7.9e-112
MMMEGNCI_01090 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MMMEGNCI_01091 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
MMMEGNCI_01092 5.2e-256 pepC 3.4.22.40 E aminopeptidase
MMMEGNCI_01093 1.9e-175 oppF P Belongs to the ABC transporter superfamily
MMMEGNCI_01094 5.1e-198 oppD P Belongs to the ABC transporter superfamily
MMMEGNCI_01095 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMMEGNCI_01096 2.4e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMMEGNCI_01097 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MMMEGNCI_01098 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
MMMEGNCI_01099 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MMMEGNCI_01100 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MMMEGNCI_01101 1.7e-184 G Transmembrane secretion effector
MMMEGNCI_01102 6.1e-136 V ABC transporter transmembrane region
MMMEGNCI_01103 1.4e-223 L transposase, IS605 OrfB family
MMMEGNCI_01104 1.1e-75 V ABC transporter transmembrane region
MMMEGNCI_01105 1.4e-118 D Alpha beta
MMMEGNCI_01106 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MMMEGNCI_01107 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
MMMEGNCI_01108 1.6e-85
MMMEGNCI_01109 2.7e-74
MMMEGNCI_01110 1.4e-140 hlyX S Transporter associated domain
MMMEGNCI_01111 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MMMEGNCI_01112 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
MMMEGNCI_01113 0.0 clpE O Belongs to the ClpA ClpB family
MMMEGNCI_01114 0.0 snf 2.7.11.1 KL domain protein
MMMEGNCI_01115 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MMMEGNCI_01116 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MMMEGNCI_01117 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MMMEGNCI_01118 5.6e-183 K Transcriptional regulator
MMMEGNCI_01119 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
MMMEGNCI_01120 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MMMEGNCI_01121 4e-57 K Helix-turn-helix domain
MMMEGNCI_01122 1.5e-80
MMMEGNCI_01123 1.6e-73 marR K Transcriptional regulator, MarR family
MMMEGNCI_01124 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MMMEGNCI_01125 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MMMEGNCI_01126 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MMMEGNCI_01127 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MMMEGNCI_01128 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MMMEGNCI_01129 2.9e-107 IQ reductase
MMMEGNCI_01130 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MMMEGNCI_01131 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MMMEGNCI_01132 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MMMEGNCI_01133 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MMMEGNCI_01134 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MMMEGNCI_01135 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MMMEGNCI_01136 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MMMEGNCI_01137 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MMMEGNCI_01138 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMMEGNCI_01141 3.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
MMMEGNCI_01142 1.3e-273 E amino acid
MMMEGNCI_01143 5.2e-26 L Helicase C-terminal domain protein
MMMEGNCI_01144 0.0 L Helicase C-terminal domain protein
MMMEGNCI_01145 4.8e-205 pbpX1 V Beta-lactamase
MMMEGNCI_01146 5.1e-226 N Uncharacterized conserved protein (DUF2075)
MMMEGNCI_01147 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MMMEGNCI_01148 3.4e-100 2.7.6.5 T Region found in RelA / SpoT proteins
MMMEGNCI_01149 1.2e-104 K response regulator
MMMEGNCI_01150 1.1e-103 sptS 2.7.13.3 T Histidine kinase
MMMEGNCI_01151 2.6e-103 sptS 2.7.13.3 T Histidine kinase
MMMEGNCI_01152 7.2e-209 EGP Major facilitator Superfamily
MMMEGNCI_01153 2.3e-69 O OsmC-like protein
MMMEGNCI_01154 2.2e-85 S Protein of unknown function (DUF805)
MMMEGNCI_01155 2.2e-78
MMMEGNCI_01156 3.1e-93
MMMEGNCI_01157 9.9e-180
MMMEGNCI_01158 5.8e-83 S Fic/DOC family
MMMEGNCI_01159 7.4e-275 yjeM E Amino Acid
MMMEGNCI_01160 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MMMEGNCI_01161 5.6e-36
MMMEGNCI_01162 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MMMEGNCI_01163 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
MMMEGNCI_01164 2.8e-135
MMMEGNCI_01165 1.3e-258 glnPH2 P ABC transporter permease
MMMEGNCI_01166 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MMMEGNCI_01167 6.4e-224 S Cysteine-rich secretory protein family
MMMEGNCI_01168 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MMMEGNCI_01169 1.4e-112
MMMEGNCI_01170 2.2e-202 yibE S overlaps another CDS with the same product name
MMMEGNCI_01171 4.9e-129 yibF S overlaps another CDS with the same product name
MMMEGNCI_01172 8.7e-145 I alpha/beta hydrolase fold
MMMEGNCI_01173 0.0 G Belongs to the glycosyl hydrolase 31 family
MMMEGNCI_01174 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MMMEGNCI_01175 5.4e-13
MMMEGNCI_01176 3e-37
MMMEGNCI_01177 2.4e-110 K WHG domain
MMMEGNCI_01178 3.2e-103 L An automated process has identified a potential problem with this gene model
MMMEGNCI_01179 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MMMEGNCI_01180 2.6e-115 dedA S SNARE-like domain protein
MMMEGNCI_01181 3.7e-100 S Protein of unknown function (DUF1461)
MMMEGNCI_01182 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MMMEGNCI_01183 2.6e-92 yutD S Protein of unknown function (DUF1027)
MMMEGNCI_01184 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MMMEGNCI_01185 4.3e-55
MMMEGNCI_01186 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MMMEGNCI_01187 1.2e-180 ccpA K catabolite control protein A
MMMEGNCI_01188 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MMMEGNCI_01189 1.3e-36
MMMEGNCI_01190 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MMMEGNCI_01191 3.7e-146 ykuT M mechanosensitive ion channel
MMMEGNCI_01192 6.9e-100 V ATPases associated with a variety of cellular activities
MMMEGNCI_01193 1.7e-139
MMMEGNCI_01194 5.4e-113
MMMEGNCI_01195 6.4e-164 D nuclear chromosome segregation
MMMEGNCI_01196 1.2e-105 G Phosphoglycerate mutase family
MMMEGNCI_01197 2.6e-89 G Histidine phosphatase superfamily (branch 1)
MMMEGNCI_01198 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
MMMEGNCI_01199 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MMMEGNCI_01201 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MMMEGNCI_01203 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MMMEGNCI_01204 1.8e-184 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MMMEGNCI_01205 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MMMEGNCI_01206 3.7e-143 K SIS domain
MMMEGNCI_01207 4.3e-227 slpX S SLAP domain
MMMEGNCI_01208 1.3e-22 3.6.4.12 S transposase or invertase
MMMEGNCI_01209 6.6e-11
MMMEGNCI_01210 3.2e-240 npr 1.11.1.1 C NADH oxidase
MMMEGNCI_01213 4.4e-239 oppA2 E ABC transporter, substratebinding protein
MMMEGNCI_01214 3.4e-45 oppA2 E ABC transporter, substratebinding protein
MMMEGNCI_01215 3.3e-179
MMMEGNCI_01216 4.6e-123 gntR1 K UTRA
MMMEGNCI_01217 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MMMEGNCI_01218 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MMMEGNCI_01219 1.7e-204 csaB M Glycosyl transferases group 1
MMMEGNCI_01220 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MMMEGNCI_01221 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MMMEGNCI_01222 1.4e-204 tnpB L Putative transposase DNA-binding domain
MMMEGNCI_01223 0.0 pacL 3.6.3.8 P P-type ATPase
MMMEGNCI_01224 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MMMEGNCI_01225 3e-257 epsU S Polysaccharide biosynthesis protein
MMMEGNCI_01226 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
MMMEGNCI_01227 4.1e-83 ydcK S Belongs to the SprT family
MMMEGNCI_01229 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
MMMEGNCI_01230 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MMMEGNCI_01231 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MMMEGNCI_01232 5.8e-203 camS S sex pheromone
MMMEGNCI_01233 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MMMEGNCI_01234 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MMMEGNCI_01235 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MMMEGNCI_01236 2.7e-171 yegS 2.7.1.107 G Lipid kinase
MMMEGNCI_01237 4.3e-108 ybhL S Belongs to the BI1 family
MMMEGNCI_01238 2.6e-57
MMMEGNCI_01239 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
MMMEGNCI_01240 2.8e-244 nhaC C Na H antiporter NhaC
MMMEGNCI_01241 6.3e-201 pbpX V Beta-lactamase
MMMEGNCI_01242 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MMMEGNCI_01243 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
MMMEGNCI_01248 1.9e-259 emrY EGP Major facilitator Superfamily
MMMEGNCI_01249 2e-91 yxdD K Bacterial regulatory proteins, tetR family
MMMEGNCI_01250 0.0 4.2.1.53 S Myosin-crossreactive antigen
MMMEGNCI_01251 1.6e-147 S cog cog1373
MMMEGNCI_01252 0.0 fhaB M Rib/alpha-like repeat
MMMEGNCI_01253 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MMMEGNCI_01254 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MMMEGNCI_01255 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MMMEGNCI_01256 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MMMEGNCI_01257 6.8e-209 msmX P Belongs to the ABC transporter superfamily
MMMEGNCI_01258 1.3e-213 malE G Bacterial extracellular solute-binding protein
MMMEGNCI_01259 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
MMMEGNCI_01260 3.3e-147 malG P ABC transporter permease
MMMEGNCI_01261 4.3e-67 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_01264 4.8e-28
MMMEGNCI_01265 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MMMEGNCI_01266 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MMMEGNCI_01267 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MMMEGNCI_01270 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MMMEGNCI_01271 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
MMMEGNCI_01272 1.8e-230 steT_1 E amino acid
MMMEGNCI_01273 2.2e-139 puuD S peptidase C26
MMMEGNCI_01275 2.7e-171 V HNH endonuclease
MMMEGNCI_01276 6.4e-135 S PFAM Archaeal ATPase
MMMEGNCI_01277 9.2e-248 yifK E Amino acid permease
MMMEGNCI_01278 9.7e-234 cycA E Amino acid permease
MMMEGNCI_01279 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MMMEGNCI_01280 0.0 clpE O AAA domain (Cdc48 subfamily)
MMMEGNCI_01281 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
MMMEGNCI_01282 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMMEGNCI_01283 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
MMMEGNCI_01284 0.0 XK27_06780 V ABC transporter permease
MMMEGNCI_01285 1.9e-36
MMMEGNCI_01286 7.9e-291 ytgP S Polysaccharide biosynthesis protein
MMMEGNCI_01287 2.7e-137 lysA2 M Glycosyl hydrolases family 25
MMMEGNCI_01288 2.3e-133 S Protein of unknown function (DUF975)
MMMEGNCI_01289 7.6e-177 pbpX2 V Beta-lactamase
MMMEGNCI_01290 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MMMEGNCI_01291 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MMMEGNCI_01292 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
MMMEGNCI_01293 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MMMEGNCI_01294 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
MMMEGNCI_01295 4.1e-44
MMMEGNCI_01296 1e-207 ywhK S Membrane
MMMEGNCI_01297 1.5e-80 ykuL S (CBS) domain
MMMEGNCI_01298 0.0 cadA P P-type ATPase
MMMEGNCI_01299 2.8e-205 napA P Sodium/hydrogen exchanger family
MMMEGNCI_01300 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MMMEGNCI_01301 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
MMMEGNCI_01302 4.1e-276 V ABC transporter transmembrane region
MMMEGNCI_01303 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
MMMEGNCI_01304 5.4e-51
MMMEGNCI_01305 4.2e-154 EGP Major facilitator Superfamily
MMMEGNCI_01306 3e-111 ropB K Transcriptional regulator
MMMEGNCI_01307 2.7e-120 S CAAX protease self-immunity
MMMEGNCI_01308 1.6e-194 S DUF218 domain
MMMEGNCI_01309 0.0 macB_3 V ABC transporter, ATP-binding protein
MMMEGNCI_01310 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MMMEGNCI_01311 8.2e-100 S ECF transporter, substrate-specific component
MMMEGNCI_01312 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
MMMEGNCI_01313 5e-85 S PFAM Archaeal ATPase
MMMEGNCI_01314 5.7e-84 S PFAM Archaeal ATPase
MMMEGNCI_01315 7.7e-26
MMMEGNCI_01316 3.1e-71 2.5.1.74 H UbiA prenyltransferase family
MMMEGNCI_01317 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MMMEGNCI_01318 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
MMMEGNCI_01319 1.4e-36 S Cytochrome B5
MMMEGNCI_01320 6e-168 arbZ I Phosphate acyltransferases
MMMEGNCI_01321 1.6e-182 arbY M Glycosyl transferase family 8
MMMEGNCI_01322 5e-184 arbY M Glycosyl transferase family 8
MMMEGNCI_01323 5e-156 arbx M Glycosyl transferase family 8
MMMEGNCI_01324 1.3e-147 arbV 2.3.1.51 I Acyl-transferase
MMMEGNCI_01326 4.9e-34
MMMEGNCI_01328 4.8e-131 K response regulator
MMMEGNCI_01329 2.2e-305 vicK 2.7.13.3 T Histidine kinase
MMMEGNCI_01330 1.6e-257 yycH S YycH protein
MMMEGNCI_01331 3.4e-149 yycI S YycH protein
MMMEGNCI_01332 4.1e-147 vicX 3.1.26.11 S domain protein
MMMEGNCI_01333 1.6e-161 htrA 3.4.21.107 O serine protease
MMMEGNCI_01334 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MMMEGNCI_01335 1.5e-92 yicL EG EamA-like transporter family
MMMEGNCI_01336 5e-165 EG EamA-like transporter family
MMMEGNCI_01337 3.1e-162 EG EamA-like transporter family
MMMEGNCI_01338 2e-32
MMMEGNCI_01339 7.8e-38
MMMEGNCI_01340 2.6e-155
MMMEGNCI_01343 1.8e-81 M NlpC/P60 family
MMMEGNCI_01344 2.1e-131 cobQ S glutamine amidotransferase
MMMEGNCI_01345 6.5e-64 L RelB antitoxin
MMMEGNCI_01347 2.4e-49 EGP Major facilitator Superfamily
MMMEGNCI_01348 2.4e-45 EGP Major facilitator Superfamily
MMMEGNCI_01349 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
MMMEGNCI_01350 0.0 tetP J elongation factor G
MMMEGNCI_01351 3.5e-160 yvgN C Aldo keto reductase
MMMEGNCI_01352 2e-155 P CorA-like Mg2+ transporter protein
MMMEGNCI_01353 1.6e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MMMEGNCI_01354 4.9e-174 ABC-SBP S ABC transporter
MMMEGNCI_01355 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MMMEGNCI_01356 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
MMMEGNCI_01357 5.2e-248 G Major Facilitator
MMMEGNCI_01358 4.1e-18
MMMEGNCI_01359 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MMMEGNCI_01360 1.4e-176 K AI-2E family transporter
MMMEGNCI_01361 8.6e-97 oppA E ABC transporter substrate-binding protein
MMMEGNCI_01362 1.2e-232 oppA E ABC transporter substrate-binding protein
MMMEGNCI_01363 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MMMEGNCI_01364 1.3e-71 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MMMEGNCI_01365 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MMMEGNCI_01367 2.6e-146 S Putative ABC-transporter type IV
MMMEGNCI_01368 1.7e-07 S LPXTG cell wall anchor motif
MMMEGNCI_01369 0.0 pepF E oligoendopeptidase F
MMMEGNCI_01370 2.9e-31
MMMEGNCI_01371 1.3e-69 doc S Prophage maintenance system killer protein
MMMEGNCI_01374 4.6e-27 S Enterocin A Immunity
MMMEGNCI_01375 1.7e-22 blpT
MMMEGNCI_01376 2.6e-138 S TerB-C domain
MMMEGNCI_01377 1.4e-245 P P-loop Domain of unknown function (DUF2791)
MMMEGNCI_01378 0.0 lhr L DEAD DEAH box helicase
MMMEGNCI_01379 1.4e-60
MMMEGNCI_01380 4.3e-228 amtB P ammonium transporter
MMMEGNCI_01381 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MMMEGNCI_01383 6.2e-59 psiE S Phosphate-starvation-inducible E
MMMEGNCI_01384 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
MMMEGNCI_01385 2.9e-69 S Iron-sulphur cluster biosynthesis
MMMEGNCI_01387 2.3e-30
MMMEGNCI_01388 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
MMMEGNCI_01389 6.2e-12
MMMEGNCI_01390 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMMEGNCI_01391 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMMEGNCI_01392 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMMEGNCI_01393 5.8e-78 M LysM domain protein
MMMEGNCI_01395 1.9e-117 cps1D M Domain of unknown function (DUF4422)
MMMEGNCI_01396 6.7e-110 rfbP M Bacterial sugar transferase
MMMEGNCI_01397 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
MMMEGNCI_01398 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MMMEGNCI_01399 6.5e-146 epsB M biosynthesis protein
MMMEGNCI_01400 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MMMEGNCI_01402 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MMMEGNCI_01403 3.5e-175 S Cysteine-rich secretory protein family
MMMEGNCI_01404 1.6e-41
MMMEGNCI_01405 2.6e-118 M NlpC/P60 family
MMMEGNCI_01406 1.4e-136 M NlpC P60 family protein
MMMEGNCI_01407 5e-88 M NlpC/P60 family
MMMEGNCI_01408 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
MMMEGNCI_01409 3.9e-42
MMMEGNCI_01410 2.9e-279 S O-antigen ligase like membrane protein
MMMEGNCI_01411 3.3e-112
MMMEGNCI_01412 9.5e-161 tnpB L Putative transposase DNA-binding domain
MMMEGNCI_01413 1e-53 tnpB L Putative transposase DNA-binding domain
MMMEGNCI_01414 5.5e-77 nrdI F NrdI Flavodoxin like
MMMEGNCI_01415 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MMMEGNCI_01416 2.5e-68
MMMEGNCI_01417 9.1e-112 yvpB S Peptidase_C39 like family
MMMEGNCI_01418 1.1e-83 S Threonine/Serine exporter, ThrE
MMMEGNCI_01419 2.4e-136 thrE S Putative threonine/serine exporter
MMMEGNCI_01420 8.9e-292 S ABC transporter
MMMEGNCI_01421 8.3e-58
MMMEGNCI_01422 5e-72 rimL J Acetyltransferase (GNAT) domain
MMMEGNCI_01423 1.4e-34
MMMEGNCI_01424 1.2e-30
MMMEGNCI_01425 1.8e-111 S Protein of unknown function (DUF554)
MMMEGNCI_01426 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MMMEGNCI_01427 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MMMEGNCI_01428 1.7e-129 manY G PTS system
MMMEGNCI_01429 1e-173 manN G system, mannose fructose sorbose family IID component
MMMEGNCI_01430 1.1e-62 manO S Domain of unknown function (DUF956)
MMMEGNCI_01431 3.3e-158 K Transcriptional regulator
MMMEGNCI_01432 1.3e-85 maa S transferase hexapeptide repeat
MMMEGNCI_01433 1.3e-241 cycA E Amino acid permease
MMMEGNCI_01434 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MMMEGNCI_01435 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MMMEGNCI_01436 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MMMEGNCI_01437 3.4e-305 mtlR K Mga helix-turn-helix domain
MMMEGNCI_01438 4.7e-61 mtlR K Mga helix-turn-helix domain
MMMEGNCI_01439 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MMMEGNCI_01440 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMMEGNCI_01441 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MMMEGNCI_01442 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
MMMEGNCI_01443 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
MMMEGNCI_01444 2.1e-32
MMMEGNCI_01445 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MMMEGNCI_01446 8.2e-111 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_01447 4.1e-26 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_01448 3.9e-298 V ABC transporter transmembrane region
MMMEGNCI_01449 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MMMEGNCI_01450 1.7e-193 S TerB-C domain
MMMEGNCI_01451 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MMMEGNCI_01452 3.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MMMEGNCI_01453 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MMMEGNCI_01454 7.2e-56 yheA S Belongs to the UPF0342 family
MMMEGNCI_01455 1e-226 yhaO L Ser Thr phosphatase family protein
MMMEGNCI_01456 0.0 L AAA domain
MMMEGNCI_01457 9.3e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
MMMEGNCI_01458 7e-22
MMMEGNCI_01459 4.3e-24 S SLAP domain
MMMEGNCI_01460 7.6e-25 S SLAP domain
MMMEGNCI_01462 9.2e-119 yhiD S MgtC family
MMMEGNCI_01463 7.7e-50 I Protein of unknown function (DUF2974)
MMMEGNCI_01464 7.5e-152 I Protein of unknown function (DUF2974)
MMMEGNCI_01465 1.4e-16
MMMEGNCI_01467 6.7e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MMMEGNCI_01468 4.2e-135 V ABC transporter transmembrane region
MMMEGNCI_01469 3.7e-168 degV S DegV family
MMMEGNCI_01470 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
MMMEGNCI_01471 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MMMEGNCI_01472 5.7e-69 rplI J Binds to the 23S rRNA
MMMEGNCI_01473 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MMMEGNCI_01474 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MMMEGNCI_01475 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MMMEGNCI_01476 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MMMEGNCI_01477 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MMMEGNCI_01478 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MMMEGNCI_01479 4e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MMMEGNCI_01480 2.6e-35 yaaA S S4 domain protein YaaA
MMMEGNCI_01481 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MMMEGNCI_01482 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MMMEGNCI_01483 5.9e-199 L Transposase and inactivated derivatives, IS30 family
MMMEGNCI_01484 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MMMEGNCI_01485 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MMMEGNCI_01486 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MMMEGNCI_01487 1.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MMMEGNCI_01488 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MMMEGNCI_01489 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MMMEGNCI_01490 9.5e-31
MMMEGNCI_01491 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MMMEGNCI_01492 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MMMEGNCI_01493 1.2e-100 treR K UTRA
MMMEGNCI_01494 3.3e-283 treB G phosphotransferase system
MMMEGNCI_01495 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MMMEGNCI_01496 1.9e-191 yrvN L AAA C-terminal domain
MMMEGNCI_01497 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MMMEGNCI_01498 9e-83 K Acetyltransferase (GNAT) domain
MMMEGNCI_01499 2.9e-229 S Putative peptidoglycan binding domain
MMMEGNCI_01500 8.3e-94 S ECF-type riboflavin transporter, S component
MMMEGNCI_01501 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MMMEGNCI_01502 9.3e-204 pbpX1 V Beta-lactamase
MMMEGNCI_01503 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
MMMEGNCI_01504 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MMMEGNCI_01505 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
MMMEGNCI_01506 6.1e-114 3.6.1.27 I Acid phosphatase homologues
MMMEGNCI_01507 2.4e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MMMEGNCI_01508 0.0 uvrA3 L excinuclease ABC, A subunit
MMMEGNCI_01509 9.9e-82 C Flavodoxin
MMMEGNCI_01511 1.6e-25 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_01512 1.2e-11
MMMEGNCI_01513 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
MMMEGNCI_01514 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MMMEGNCI_01515 5.9e-264 lctP C L-lactate permease
MMMEGNCI_01516 5e-129 znuB U ABC 3 transport family
MMMEGNCI_01517 1.6e-117 fhuC P ABC transporter
MMMEGNCI_01518 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
MMMEGNCI_01519 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
MMMEGNCI_01520 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
MMMEGNCI_01521 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MMMEGNCI_01522 1.8e-136 fruR K DeoR C terminal sensor domain
MMMEGNCI_01523 1.8e-218 natB CP ABC-2 family transporter protein
MMMEGNCI_01524 1.1e-164 natA S ABC transporter, ATP-binding protein
MMMEGNCI_01525 1.7e-67
MMMEGNCI_01526 2e-23
MMMEGNCI_01527 8.2e-31 yozG K Transcriptional regulator
MMMEGNCI_01528 3.7e-83
MMMEGNCI_01529 3e-21
MMMEGNCI_01533 2.2e-129 blpT
MMMEGNCI_01534 1.4e-107 M Transport protein ComB
MMMEGNCI_01535 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MMMEGNCI_01536 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
MMMEGNCI_01537 4.9e-111 ybbL S ABC transporter, ATP-binding protein
MMMEGNCI_01538 0.0 S SH3-like domain
MMMEGNCI_01539 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MMMEGNCI_01540 2.1e-171 whiA K May be required for sporulation
MMMEGNCI_01541 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MMMEGNCI_01542 6.2e-165 rapZ S Displays ATPase and GTPase activities
MMMEGNCI_01543 4.1e-90 S Short repeat of unknown function (DUF308)
MMMEGNCI_01544 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MMMEGNCI_01545 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MMMEGNCI_01546 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MMMEGNCI_01547 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MMMEGNCI_01548 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MMMEGNCI_01549 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MMMEGNCI_01550 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MMMEGNCI_01551 5.1e-17
MMMEGNCI_01552 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MMMEGNCI_01553 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MMMEGNCI_01554 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MMMEGNCI_01555 9.4e-132 comFC S Competence protein
MMMEGNCI_01556 4.7e-246 comFA L Helicase C-terminal domain protein
MMMEGNCI_01557 5.1e-119 yvyE 3.4.13.9 S YigZ family
MMMEGNCI_01558 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
MMMEGNCI_01559 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
MMMEGNCI_01560 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MMMEGNCI_01561 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MMMEGNCI_01562 5.2e-97 ymfM S Helix-turn-helix domain
MMMEGNCI_01563 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
MMMEGNCI_01564 1.9e-236 S Peptidase M16
MMMEGNCI_01565 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
MMMEGNCI_01566 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MMMEGNCI_01567 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
MMMEGNCI_01568 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MMMEGNCI_01569 2.6e-214 yubA S AI-2E family transporter
MMMEGNCI_01570 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MMMEGNCI_01571 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MMMEGNCI_01572 3.2e-10 S Domain of unknown function DUF87
MMMEGNCI_01573 1.2e-63 S SIR2-like domain
MMMEGNCI_01574 8.3e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MMMEGNCI_01575 2.3e-51 3.1.21.3 V Type I restriction modification DNA specificity domain
MMMEGNCI_01576 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
MMMEGNCI_01577 3.4e-42 S RloB-like protein
MMMEGNCI_01578 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
MMMEGNCI_01579 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
MMMEGNCI_01580 0.0 S SLAP domain
MMMEGNCI_01582 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
MMMEGNCI_01583 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
MMMEGNCI_01584 1.5e-239 G Bacterial extracellular solute-binding protein
MMMEGNCI_01585 5.7e-18
MMMEGNCI_01586 1.3e-116 S Peptidase family M23
MMMEGNCI_01587 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MMMEGNCI_01589 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMMEGNCI_01590 9.4e-118
MMMEGNCI_01591 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MMMEGNCI_01592 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MMMEGNCI_01593 2.6e-280 thrC 4.2.3.1 E Threonine synthase
MMMEGNCI_01594 2.2e-179 lysC 2.7.2.4 E Belongs to the aspartokinase family
MMMEGNCI_01595 9.9e-39 3.6.3.6 P Cation transporter/ATPase, N-terminus
MMMEGNCI_01596 1.9e-19
MMMEGNCI_01597 5.9e-45
MMMEGNCI_01598 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MMMEGNCI_01600 2.1e-45 S PFAM Archaeal ATPase
MMMEGNCI_01601 7.3e-74
MMMEGNCI_01602 0.0 kup P Transport of potassium into the cell
MMMEGNCI_01603 0.0 pepO 3.4.24.71 O Peptidase family M13
MMMEGNCI_01604 1.4e-210 yttB EGP Major facilitator Superfamily
MMMEGNCI_01605 1.5e-230 XK27_04775 S PAS domain
MMMEGNCI_01606 6.2e-103 S Iron-sulfur cluster assembly protein
MMMEGNCI_01607 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MMMEGNCI_01608 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MMMEGNCI_01609 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
MMMEGNCI_01610 0.0 asnB 6.3.5.4 E Asparagine synthase
MMMEGNCI_01611 1.3e-270 S Calcineurin-like phosphoesterase
MMMEGNCI_01612 3.9e-84
MMMEGNCI_01613 1.6e-105 tag 3.2.2.20 L glycosylase
MMMEGNCI_01614 4.5e-168 L COG3385 FOG Transposase and inactivated derivatives
MMMEGNCI_01616 5.5e-30
MMMEGNCI_01617 4.3e-40 S Protein of unknown function (DUF2922)
MMMEGNCI_01618 3.1e-131 S SLAP domain
MMMEGNCI_01620 5.3e-41
MMMEGNCI_01621 1.2e-77 K DNA-templated transcription, initiation
MMMEGNCI_01622 1.1e-25
MMMEGNCI_01623 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MMMEGNCI_01624 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MMMEGNCI_01625 1.4e-104 S SLAP domain
MMMEGNCI_01627 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MMMEGNCI_01628 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MMMEGNCI_01629 0.0 yjbQ P TrkA C-terminal domain protein
MMMEGNCI_01630 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MMMEGNCI_01631 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
MMMEGNCI_01632 2.1e-130
MMMEGNCI_01633 2.1e-116
MMMEGNCI_01634 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MMMEGNCI_01635 1.4e-98 G Aldose 1-epimerase
MMMEGNCI_01636 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MMMEGNCI_01637 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MMMEGNCI_01638 0.0 XK27_08315 M Sulfatase
MMMEGNCI_01639 3.7e-93 sip L Belongs to the 'phage' integrase family
MMMEGNCI_01640 6.2e-12
MMMEGNCI_01641 5.6e-08 M Host cell surface-exposed lipoprotein
MMMEGNCI_01642 2.4e-07 S Pfam:DUF955
MMMEGNCI_01643 8.8e-22 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_01644 1.4e-17 K Helix-turn-helix XRE-family like proteins
MMMEGNCI_01645 4.9e-94 S DNA binding
MMMEGNCI_01651 1.8e-31 S Helix-turn-helix domain
MMMEGNCI_01652 5.5e-18
MMMEGNCI_01654 4.6e-45
MMMEGNCI_01655 1.6e-128 S Protein of unknown function (DUF1351)
MMMEGNCI_01656 5.3e-131 S ERF superfamily
MMMEGNCI_01657 1.2e-100 L Helix-turn-helix domain
MMMEGNCI_01661 1.6e-65 S ORF6C domain
MMMEGNCI_01663 3.7e-37 S VRR_NUC
MMMEGNCI_01665 3.3e-09 arpU S Phage transcriptional regulator, ArpU family
MMMEGNCI_01668 3e-19 ps333 L Terminase small subunit
MMMEGNCI_01669 1.1e-201 S Terminase-like family
MMMEGNCI_01670 6.2e-135 S Protein of unknown function (DUF1073)
MMMEGNCI_01671 1.3e-47 S Phage Mu protein F like protein
MMMEGNCI_01672 5e-12 S Lysin motif
MMMEGNCI_01673 1.6e-57 S Uncharacterized protein conserved in bacteria (DUF2213)
MMMEGNCI_01674 4.1e-34
MMMEGNCI_01675 2.4e-93 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
MMMEGNCI_01676 9.2e-20 S Protein of unknown function (DUF4054)
MMMEGNCI_01677 1e-29
MMMEGNCI_01678 1.6e-25
MMMEGNCI_01679 4.3e-31
MMMEGNCI_01680 3.5e-103 Z012_02110 S Protein of unknown function (DUF3383)
MMMEGNCI_01681 9.3e-29
MMMEGNCI_01682 2.9e-09
MMMEGNCI_01684 1e-220 3.4.14.13 M Phage tail tape measure protein TP901
MMMEGNCI_01685 3.8e-59 M LysM domain
MMMEGNCI_01686 2.7e-46
MMMEGNCI_01687 1.1e-102
MMMEGNCI_01688 4.9e-39
MMMEGNCI_01689 6.4e-31
MMMEGNCI_01690 8.8e-114 Z012_12235 S Baseplate J-like protein
MMMEGNCI_01691 2.9e-09
MMMEGNCI_01692 2.3e-34
MMMEGNCI_01697 8.4e-39
MMMEGNCI_01698 1.1e-18 S Phage uncharacterised protein (Phage_XkdX)
MMMEGNCI_01701 4.3e-17
MMMEGNCI_01702 2.9e-29
MMMEGNCI_01703 2e-171 M Glycosyl hydrolases family 25
MMMEGNCI_01704 5.7e-272 P Sodium:sulfate symporter transmembrane region
MMMEGNCI_01705 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
MMMEGNCI_01706 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
MMMEGNCI_01707 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MMMEGNCI_01708 9.5e-261 frdC 1.3.5.4 C FAD binding domain
MMMEGNCI_01709 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MMMEGNCI_01710 3.4e-73 metI P ABC transporter permease
MMMEGNCI_01711 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MMMEGNCI_01712 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
MMMEGNCI_01713 2.4e-175 F DNA/RNA non-specific endonuclease
MMMEGNCI_01714 0.0 aha1 P E1-E2 ATPase
MMMEGNCI_01715 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MMMEGNCI_01716 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MMMEGNCI_01717 1.2e-250 yifK E Amino acid permease
MMMEGNCI_01718 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
MMMEGNCI_01719 4.5e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MMMEGNCI_01721 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMMEGNCI_01722 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
MMMEGNCI_01723 1.3e-61 M Glycosyl hydrolases family 25
MMMEGNCI_01724 2.6e-61 M Glycosyl hydrolases family 25
MMMEGNCI_01725 6.3e-50 yicL EG EamA-like transporter family
MMMEGNCI_01726 4.3e-107
MMMEGNCI_01727 1.1e-110
MMMEGNCI_01728 5.8e-186 XK27_05540 S DUF218 domain
MMMEGNCI_01729 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
MMMEGNCI_01730 2e-83
MMMEGNCI_01731 1.1e-11
MMMEGNCI_01732 4.7e-25 S Protein conserved in bacteria
MMMEGNCI_01733 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
MMMEGNCI_01734 1.2e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MMMEGNCI_01735 6.4e-113 S SLAP domain
MMMEGNCI_01736 8.4e-89
MMMEGNCI_01737 3e-09 isdH M Iron Transport-associated domain
MMMEGNCI_01738 6.3e-123 M Iron Transport-associated domain
MMMEGNCI_01739 8.7e-159 isdE P Periplasmic binding protein
MMMEGNCI_01740 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMMEGNCI_01741 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
MMMEGNCI_01742 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MMMEGNCI_01743 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MMMEGNCI_01744 1.3e-38 S RelB antitoxin
MMMEGNCI_01745 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MMMEGNCI_01746 1.1e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MMMEGNCI_01747 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MMMEGNCI_01748 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MMMEGNCI_01750 8.3e-138 L An automated process has identified a potential problem with this gene model
MMMEGNCI_01751 2.8e-48 S Peptidase propeptide and YPEB domain
MMMEGNCI_01752 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MMMEGNCI_01753 3.5e-32 ykzG S Belongs to the UPF0356 family
MMMEGNCI_01754 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MMMEGNCI_01755 1.9e-75 M LysM domain
MMMEGNCI_01756 1.3e-42
MMMEGNCI_01758 4.9e-35
MMMEGNCI_01759 4.5e-76 yniG EGP Major facilitator Superfamily
MMMEGNCI_01760 5.4e-237 L transposase, IS605 OrfB family
MMMEGNCI_01761 1.4e-109 yniG EGP Major facilitator Superfamily
MMMEGNCI_01762 2.4e-128 S cog cog1373
MMMEGNCI_01763 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
MMMEGNCI_01764 6.6e-44
MMMEGNCI_01765 1.6e-171 2.7.1.2 GK ROK family
MMMEGNCI_01766 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MMMEGNCI_01767 2e-295 S SLAP domain
MMMEGNCI_01768 5.3e-80
MMMEGNCI_01769 3.7e-20
MMMEGNCI_01770 3.2e-139
MMMEGNCI_01771 3.7e-261 V ABC transporter transmembrane region
MMMEGNCI_01772 1.4e-37 S Putative adhesin
MMMEGNCI_01773 1.3e-260 emrY EGP Major facilitator Superfamily
MMMEGNCI_01774 1.1e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MMMEGNCI_01775 7.6e-239 pyrP F Permease
MMMEGNCI_01776 1.9e-22 K Putative DNA-binding domain
MMMEGNCI_01777 3.9e-113 L PFAM Integrase catalytic
MMMEGNCI_01778 2e-57 clcA P chloride
MMMEGNCI_01779 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MMMEGNCI_01780 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
MMMEGNCI_01781 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MMMEGNCI_01782 1.7e-284 E Amino acid permease
MMMEGNCI_01783 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
MMMEGNCI_01784 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
MMMEGNCI_01785 1.4e-115 mmuP E amino acid
MMMEGNCI_01786 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MMMEGNCI_01787 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MMMEGNCI_01788 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
MMMEGNCI_01789 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MMMEGNCI_01791 2e-178 MA20_14895 S Conserved hypothetical protein 698
MMMEGNCI_01792 1.1e-83 dps P Belongs to the Dps family
MMMEGNCI_01793 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
MMMEGNCI_01794 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MMMEGNCI_01795 1.8e-58 S Putative adhesin
MMMEGNCI_01796 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
MMMEGNCI_01797 2e-234 mepA V MATE efflux family protein
MMMEGNCI_01798 1.2e-299 I Protein of unknown function (DUF2974)
MMMEGNCI_01799 2.2e-135 pbpX1 V Beta-lactamase
MMMEGNCI_01800 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MMMEGNCI_01801 2.7e-216 aspC 2.6.1.1 E Aminotransferase
MMMEGNCI_01802 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MMMEGNCI_01803 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MMMEGNCI_01804 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MMMEGNCI_01805 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MMMEGNCI_01806 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MMMEGNCI_01807 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
MMMEGNCI_01808 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MMMEGNCI_01809 3.4e-209 yjeM E Amino Acid
MMMEGNCI_01810 7.8e-39 yjeM E Amino Acid
MMMEGNCI_01811 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
MMMEGNCI_01812 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MMMEGNCI_01813 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MMMEGNCI_01814 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MMMEGNCI_01815 1.3e-148
MMMEGNCI_01816 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MMMEGNCI_01817 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MMMEGNCI_01818 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
MMMEGNCI_01819 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
MMMEGNCI_01820 0.0 comEC S Competence protein ComEC
MMMEGNCI_01821 3.1e-79 comEA L Competence protein ComEA
MMMEGNCI_01822 2.4e-187 ylbL T Belongs to the peptidase S16 family
MMMEGNCI_01823 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MMMEGNCI_01824 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MMMEGNCI_01825 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MMMEGNCI_01826 5.9e-211 ftsW D Belongs to the SEDS family
MMMEGNCI_01827 0.0 typA T GTP-binding protein TypA
MMMEGNCI_01828 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MMMEGNCI_01829 3e-24
MMMEGNCI_01830 1.5e-152
MMMEGNCI_01831 2.4e-91 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
MMMEGNCI_01832 3.3e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
MMMEGNCI_01833 4.4e-151 S Metal-independent alpha-mannosidase (GH125)
MMMEGNCI_01834 3.4e-53
MMMEGNCI_01836 4.6e-257 pepC 3.4.22.40 E aminopeptidase
MMMEGNCI_01837 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MMMEGNCI_01838 5e-301 oppA E ABC transporter, substratebinding protein
MMMEGNCI_01839 1.6e-310 oppA E ABC transporter, substratebinding protein
MMMEGNCI_01840 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
MMMEGNCI_01841 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
MMMEGNCI_01842 6e-151 3.1.3.48 T Tyrosine phosphatase family
MMMEGNCI_01843 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MMMEGNCI_01845 3e-53 cvpA S Colicin V production protein
MMMEGNCI_01846 3.6e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MMMEGNCI_01847 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
MMMEGNCI_01848 1e-30 S cog cog1373
MMMEGNCI_01849 1.4e-15 S cog cog1373
MMMEGNCI_01850 5.2e-156 hipB K Helix-turn-helix
MMMEGNCI_01851 2.7e-151 I alpha/beta hydrolase fold
MMMEGNCI_01852 1.4e-110 yjbF S SNARE associated Golgi protein
MMMEGNCI_01853 7.5e-100 J Acetyltransferase (GNAT) domain
MMMEGNCI_01854 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MMMEGNCI_01855 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
MMMEGNCI_01856 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
MMMEGNCI_01857 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
MMMEGNCI_01858 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
MMMEGNCI_01859 9.7e-46 oppA E ABC transporter substrate-binding protein
MMMEGNCI_01860 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
MMMEGNCI_01861 2.6e-172 oppB P ABC transporter permease
MMMEGNCI_01862 1.5e-170 oppF P Belongs to the ABC transporter superfamily
MMMEGNCI_01863 3.1e-192 oppD P Belongs to the ABC transporter superfamily
MMMEGNCI_01864 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MMMEGNCI_01865 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MMMEGNCI_01866 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MMMEGNCI_01867 1.7e-304 yloV S DAK2 domain fusion protein YloV
MMMEGNCI_01868 1.5e-56 asp S Asp23 family, cell envelope-related function
MMMEGNCI_01869 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MMMEGNCI_01870 1.4e-30
MMMEGNCI_01871 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
MMMEGNCI_01872 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MMMEGNCI_01873 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MMMEGNCI_01874 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MMMEGNCI_01875 1.1e-138 stp 3.1.3.16 T phosphatase
MMMEGNCI_01876 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MMMEGNCI_01877 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MMMEGNCI_01878 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MMMEGNCI_01879 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MMMEGNCI_01880 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MMMEGNCI_01881 1.1e-77 6.3.3.2 S ASCH
MMMEGNCI_01882 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
MMMEGNCI_01883 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MMMEGNCI_01884 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MMMEGNCI_01885 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MMMEGNCI_01886 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MMMEGNCI_01887 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MMMEGNCI_01888 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MMMEGNCI_01889 3.4e-71 yqhY S Asp23 family, cell envelope-related function
MMMEGNCI_01890 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MMMEGNCI_01891 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MMMEGNCI_01892 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MMMEGNCI_01893 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MMMEGNCI_01894 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMMEGNCI_01895 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
MMMEGNCI_01897 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MMMEGNCI_01898 4.3e-298 S Predicted membrane protein (DUF2207)
MMMEGNCI_01899 2.8e-157 cinI S Serine hydrolase (FSH1)
MMMEGNCI_01900 1e-205 M Glycosyl hydrolases family 25
MMMEGNCI_01902 8.5e-178 I Carboxylesterase family
MMMEGNCI_01903 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
MMMEGNCI_01904 8.3e-277 V ABC-type multidrug transport system, ATPase and permease components
MMMEGNCI_01905 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
MMMEGNCI_01906 1.7e-148 S haloacid dehalogenase-like hydrolase
MMMEGNCI_01907 7e-50
MMMEGNCI_01908 1.9e-37
MMMEGNCI_01909 1.2e-63 S Alpha beta hydrolase
MMMEGNCI_01910 1e-23 S Alpha beta hydrolase
MMMEGNCI_01911 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MMMEGNCI_01912 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MMMEGNCI_01913 2.1e-168 dnaI L Primosomal protein DnaI
MMMEGNCI_01914 5.1e-251 dnaB L Replication initiation and membrane attachment
MMMEGNCI_01915 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MMMEGNCI_01916 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MMMEGNCI_01917 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MMMEGNCI_01918 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MMMEGNCI_01919 3.5e-25 qmcA O prohibitin homologues
MMMEGNCI_01920 7.4e-105 qmcA O prohibitin homologues
MMMEGNCI_01921 8e-51 L RelB antitoxin
MMMEGNCI_01922 2.2e-187 S Bacteriocin helveticin-J
MMMEGNCI_01923 4.4e-283 M Peptidase family M1 domain
MMMEGNCI_01924 1.8e-176 S SLAP domain
MMMEGNCI_01925 6.9e-218 mepA V MATE efflux family protein
MMMEGNCI_01926 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MMMEGNCI_01927 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MMMEGNCI_01928 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MMMEGNCI_01930 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MMMEGNCI_01931 6.5e-221 ecsB U ABC transporter
MMMEGNCI_01932 5.7e-135 ecsA V ABC transporter, ATP-binding protein
MMMEGNCI_01933 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
MMMEGNCI_01934 3.9e-25
MMMEGNCI_01935 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MMMEGNCI_01936 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MMMEGNCI_01937 1.1e-265
MMMEGNCI_01938 2.4e-51 S Domain of unknown function DUF1829
MMMEGNCI_01939 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MMMEGNCI_01940 1.6e-266 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
MMMEGNCI_01941 4.4e-129 K Transcriptional regulatory protein, C terminal
MMMEGNCI_01942 7.7e-67 S SdpI/YhfL protein family
MMMEGNCI_01943 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
MMMEGNCI_01944 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
MMMEGNCI_01945 2.5e-89 M Protein of unknown function (DUF3737)
MMMEGNCI_01946 7.6e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MMMEGNCI_01947 1e-12
MMMEGNCI_01949 5e-15 S Domain of Unknown Function with PDB structure (DUF3850)
MMMEGNCI_01950 2.2e-97 D VirC1 protein
MMMEGNCI_01952 5e-39 relB L RelB antitoxin
MMMEGNCI_01953 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)