ORF_ID e_value Gene_name EC_number CAZy COGs Description
KLFCKHPL_00001 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KLFCKHPL_00002 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KLFCKHPL_00003 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLFCKHPL_00004 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KLFCKHPL_00005 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KLFCKHPL_00006 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KLFCKHPL_00007 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLFCKHPL_00008 3.3e-61 3.6.1.55 F NUDIX domain
KLFCKHPL_00009 1e-79 S AAA domain
KLFCKHPL_00010 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
KLFCKHPL_00011 2.3e-168 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
KLFCKHPL_00012 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLFCKHPL_00013 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
KLFCKHPL_00014 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
KLFCKHPL_00015 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
KLFCKHPL_00016 2.1e-32
KLFCKHPL_00017 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KLFCKHPL_00018 2.3e-156 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00019 3.9e-298 V ABC transporter transmembrane region
KLFCKHPL_00020 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KLFCKHPL_00021 1.7e-193 S TerB-C domain
KLFCKHPL_00049 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
KLFCKHPL_00050 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
KLFCKHPL_00051 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLFCKHPL_00052 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLFCKHPL_00053 1.7e-29 secG U Preprotein translocase
KLFCKHPL_00054 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KLFCKHPL_00055 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KLFCKHPL_00058 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
KLFCKHPL_00061 9.4e-33 M Peptidase family M23
KLFCKHPL_00062 2.4e-159 trsE S COG0433 Predicted ATPase
KLFCKHPL_00063 8.4e-15
KLFCKHPL_00065 2.3e-32 I mechanosensitive ion channel activity
KLFCKHPL_00066 3.1e-141 U TraM recognition site of TraD and TraG
KLFCKHPL_00070 1e-30 M domain protein
KLFCKHPL_00071 7.2e-15 S SLAP domain
KLFCKHPL_00072 7.4e-40 M domain protein
KLFCKHPL_00074 1.4e-24 srtA 3.4.22.70 M sortase family
KLFCKHPL_00075 2.3e-21 S SLAP domain
KLFCKHPL_00080 5.7e-11 S Single-strand binding protein family
KLFCKHPL_00091 1.7e-25 S Domain of unknown function (DUF771)
KLFCKHPL_00092 2e-32 K Helix-turn-helix domain
KLFCKHPL_00093 5.7e-16 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00094 3.4e-29 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00095 5e-08 S Pfam:DUF955
KLFCKHPL_00096 6.4e-111 L Belongs to the 'phage' integrase family
KLFCKHPL_00098 1.6e-131 I Carboxylesterase family
KLFCKHPL_00099 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLFCKHPL_00100 1.8e-104 3.2.2.20 K acetyltransferase
KLFCKHPL_00102 4.3e-226 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLFCKHPL_00103 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
KLFCKHPL_00104 4.1e-21 K Helix-turn-helix domain, rpiR family
KLFCKHPL_00105 1.3e-71 K Helix-turn-helix domain, rpiR family
KLFCKHPL_00106 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLFCKHPL_00107 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KLFCKHPL_00108 1.5e-102 srtA 3.4.22.70 M sortase family
KLFCKHPL_00109 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KLFCKHPL_00110 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KLFCKHPL_00111 0.0 dnaK O Heat shock 70 kDa protein
KLFCKHPL_00112 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLFCKHPL_00113 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KLFCKHPL_00114 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KLFCKHPL_00115 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLFCKHPL_00116 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KLFCKHPL_00117 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLFCKHPL_00118 3.2e-47 rplGA J ribosomal protein
KLFCKHPL_00119 8.8e-47 ylxR K Protein of unknown function (DUF448)
KLFCKHPL_00120 1.4e-196 nusA K Participates in both transcription termination and antitermination
KLFCKHPL_00121 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
KLFCKHPL_00122 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLFCKHPL_00123 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KLFCKHPL_00124 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KLFCKHPL_00125 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
KLFCKHPL_00126 1.3e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLFCKHPL_00127 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KLFCKHPL_00128 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KLFCKHPL_00129 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLFCKHPL_00130 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KLFCKHPL_00131 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
KLFCKHPL_00132 2.9e-116 plsC 2.3.1.51 I Acyltransferase
KLFCKHPL_00133 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KLFCKHPL_00134 0.0 pepO 3.4.24.71 O Peptidase family M13
KLFCKHPL_00135 0.0 mdlB V ABC transporter
KLFCKHPL_00136 0.0 mdlA V ABC transporter
KLFCKHPL_00137 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
KLFCKHPL_00138 3e-38 ynzC S UPF0291 protein
KLFCKHPL_00139 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLFCKHPL_00140 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
KLFCKHPL_00141 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
KLFCKHPL_00142 4.6e-213 S SLAP domain
KLFCKHPL_00143 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KLFCKHPL_00144 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KLFCKHPL_00145 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLFCKHPL_00146 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KLFCKHPL_00147 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLFCKHPL_00148 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KLFCKHPL_00149 2.7e-258 yfnA E amino acid
KLFCKHPL_00150 0.0 V FtsX-like permease family
KLFCKHPL_00151 4.1e-133 cysA V ABC transporter, ATP-binding protein
KLFCKHPL_00152 3.4e-23
KLFCKHPL_00154 2.5e-288 pipD E Dipeptidase
KLFCKHPL_00155 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KLFCKHPL_00156 0.0 smc D Required for chromosome condensation and partitioning
KLFCKHPL_00157 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KLFCKHPL_00158 2.1e-308 oppA E ABC transporter substrate-binding protein
KLFCKHPL_00159 3.1e-240 oppA E ABC transporter substrate-binding protein
KLFCKHPL_00160 1.1e-34 S Protein of unknown function (DUF2508)
KLFCKHPL_00161 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLFCKHPL_00162 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KLFCKHPL_00163 8.7e-84 2.4.1.58 GT8 M family 8
KLFCKHPL_00164 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLFCKHPL_00165 6.4e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KLFCKHPL_00166 9e-26
KLFCKHPL_00167 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
KLFCKHPL_00168 3.9e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
KLFCKHPL_00169 4.1e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KLFCKHPL_00170 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLFCKHPL_00171 1.7e-12 GT2,GT4 M family 8
KLFCKHPL_00172 5.7e-272 P Sodium:sulfate symporter transmembrane region
KLFCKHPL_00173 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
KLFCKHPL_00174 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
KLFCKHPL_00175 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLFCKHPL_00176 1.9e-261 frdC 1.3.5.4 C FAD binding domain
KLFCKHPL_00177 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KLFCKHPL_00178 3.4e-73 metI P ABC transporter permease
KLFCKHPL_00179 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLFCKHPL_00180 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
KLFCKHPL_00181 2.4e-175 F DNA/RNA non-specific endonuclease
KLFCKHPL_00182 0.0 aha1 P E1-E2 ATPase
KLFCKHPL_00183 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KLFCKHPL_00184 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLFCKHPL_00185 1.2e-250 yifK E Amino acid permease
KLFCKHPL_00186 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
KLFCKHPL_00187 4.8e-145 yeaE S Aldo/keto reductase family
KLFCKHPL_00188 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
KLFCKHPL_00189 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
KLFCKHPL_00190 1.3e-282 xylG 3.6.3.17 S ABC transporter
KLFCKHPL_00191 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
KLFCKHPL_00192 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
KLFCKHPL_00193 2.8e-100 S ECF transporter, substrate-specific component
KLFCKHPL_00194 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KLFCKHPL_00195 0.0 macB_3 V ABC transporter, ATP-binding protein
KLFCKHPL_00196 1.6e-194 S DUF218 domain
KLFCKHPL_00197 2.7e-120 S CAAX protease self-immunity
KLFCKHPL_00198 3e-111 ropB K Transcriptional regulator
KLFCKHPL_00199 4.2e-154 EGP Major facilitator Superfamily
KLFCKHPL_00200 5.4e-51
KLFCKHPL_00201 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00202 4.1e-276 V ABC transporter transmembrane region
KLFCKHPL_00203 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
KLFCKHPL_00204 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KLFCKHPL_00205 2.8e-205 napA P Sodium/hydrogen exchanger family
KLFCKHPL_00206 0.0 cadA P P-type ATPase
KLFCKHPL_00207 7.4e-80 ykuL S (CBS) domain
KLFCKHPL_00208 1e-207 ywhK S Membrane
KLFCKHPL_00209 4.1e-44
KLFCKHPL_00210 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
KLFCKHPL_00211 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLFCKHPL_00212 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
KLFCKHPL_00213 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLFCKHPL_00214 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KLFCKHPL_00215 7.6e-177 pbpX2 V Beta-lactamase
KLFCKHPL_00216 2.3e-133 S Protein of unknown function (DUF975)
KLFCKHPL_00217 2.7e-137 lysA2 M Glycosyl hydrolases family 25
KLFCKHPL_00218 7.9e-291 ytgP S Polysaccharide biosynthesis protein
KLFCKHPL_00219 1.9e-36
KLFCKHPL_00220 0.0 XK27_06780 V ABC transporter permease
KLFCKHPL_00221 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
KLFCKHPL_00222 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLFCKHPL_00223 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
KLFCKHPL_00224 0.0 clpE O AAA domain (Cdc48 subfamily)
KLFCKHPL_00225 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KLFCKHPL_00226 9.7e-234 cycA E Amino acid permease
KLFCKHPL_00227 9.2e-248 yifK E Amino acid permease
KLFCKHPL_00228 6.4e-135 S PFAM Archaeal ATPase
KLFCKHPL_00229 2.4e-172 V HNH endonuclease
KLFCKHPL_00231 2.2e-139 puuD S peptidase C26
KLFCKHPL_00232 1.8e-230 steT_1 E amino acid
KLFCKHPL_00233 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
KLFCKHPL_00234 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KLFCKHPL_00237 9e-20 ywzB S Protein of unknown function (DUF1146)
KLFCKHPL_00238 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KLFCKHPL_00239 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLFCKHPL_00240 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLFCKHPL_00241 2.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLFCKHPL_00242 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLFCKHPL_00243 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KLFCKHPL_00244 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLFCKHPL_00245 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
KLFCKHPL_00246 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLFCKHPL_00247 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KLFCKHPL_00248 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KLFCKHPL_00249 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLFCKHPL_00250 1.3e-113 tdk 2.7.1.21 F thymidine kinase
KLFCKHPL_00251 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
KLFCKHPL_00254 3.9e-195 ampC V Beta-lactamase
KLFCKHPL_00255 3.8e-217 EGP Major facilitator Superfamily
KLFCKHPL_00256 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
KLFCKHPL_00257 3.8e-105 vanZ V VanZ like family
KLFCKHPL_00258 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLFCKHPL_00259 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
KLFCKHPL_00260 4.4e-129 K Transcriptional regulatory protein, C terminal
KLFCKHPL_00261 7.7e-67 S SdpI/YhfL protein family
KLFCKHPL_00262 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
KLFCKHPL_00263 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
KLFCKHPL_00264 2.5e-89 M Protein of unknown function (DUF3737)
KLFCKHPL_00266 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLFCKHPL_00267 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
KLFCKHPL_00268 1.6e-21
KLFCKHPL_00269 3.8e-77 comGF U Putative Competence protein ComGF
KLFCKHPL_00270 2.3e-41
KLFCKHPL_00271 1.8e-69
KLFCKHPL_00272 3.1e-43 comGC U competence protein ComGC
KLFCKHPL_00273 1.7e-171 comGB NU type II secretion system
KLFCKHPL_00274 1.7e-179 comGA NU Type II IV secretion system protein
KLFCKHPL_00275 8.9e-133 yebC K Transcriptional regulatory protein
KLFCKHPL_00276 7.6e-94 S VanZ like family
KLFCKHPL_00277 3.5e-101 ylbE GM NAD(P)H-binding
KLFCKHPL_00278 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLFCKHPL_00280 1.3e-160 L hmm pf00665
KLFCKHPL_00281 5.8e-100 L Helix-turn-helix domain
KLFCKHPL_00282 2e-310 E Amino acid permease
KLFCKHPL_00284 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KLFCKHPL_00285 2.2e-90 2.7.7.65 T GGDEF domain
KLFCKHPL_00286 8.2e-36
KLFCKHPL_00287 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
KLFCKHPL_00288 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
KLFCKHPL_00289 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KLFCKHPL_00290 1e-149 D Alpha beta
KLFCKHPL_00291 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KLFCKHPL_00292 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLFCKHPL_00293 7e-142 licT K CAT RNA binding domain
KLFCKHPL_00294 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KLFCKHPL_00295 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLFCKHPL_00296 1.6e-118
KLFCKHPL_00297 1.8e-75 K Penicillinase repressor
KLFCKHPL_00298 1.4e-147 S hydrolase
KLFCKHPL_00299 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLFCKHPL_00300 2e-172 ybbR S YbbR-like protein
KLFCKHPL_00301 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KLFCKHPL_00302 7.3e-208 potD P ABC transporter
KLFCKHPL_00303 4.8e-127 potC P ABC transporter permease
KLFCKHPL_00304 1.3e-129 potB P ABC transporter permease
KLFCKHPL_00305 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KLFCKHPL_00306 2e-163 murB 1.3.1.98 M Cell wall formation
KLFCKHPL_00307 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
KLFCKHPL_00308 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KLFCKHPL_00309 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KLFCKHPL_00310 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLFCKHPL_00311 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
KLFCKHPL_00312 1.2e-94
KLFCKHPL_00313 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
KLFCKHPL_00314 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLFCKHPL_00315 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KLFCKHPL_00316 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLFCKHPL_00317 2.6e-189 cggR K Putative sugar-binding domain
KLFCKHPL_00319 2.8e-290
KLFCKHPL_00320 4.6e-274 ycaM E amino acid
KLFCKHPL_00321 3.1e-139 S Cysteine-rich secretory protein family
KLFCKHPL_00322 4.2e-77 K MerR HTH family regulatory protein
KLFCKHPL_00323 2.4e-262 lmrB EGP Major facilitator Superfamily
KLFCKHPL_00324 3.1e-48 S Domain of unknown function (DUF4811)
KLFCKHPL_00325 0.0 L Plasmid pRiA4b ORF-3-like protein
KLFCKHPL_00326 1.1e-282 phoR 2.7.13.3 T Histidine kinase
KLFCKHPL_00327 9.5e-121 T Transcriptional regulatory protein, C terminal
KLFCKHPL_00328 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
KLFCKHPL_00329 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLFCKHPL_00330 1.2e-152 pstA P Phosphate transport system permease protein PstA
KLFCKHPL_00331 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KLFCKHPL_00332 1.2e-144 pstS P Phosphate
KLFCKHPL_00333 1.3e-30
KLFCKHPL_00334 1.4e-191 oppA E ABC transporter, substratebinding protein
KLFCKHPL_00335 4.7e-275 ytgP S Polysaccharide biosynthesis protein
KLFCKHPL_00336 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLFCKHPL_00337 1.1e-121 3.6.1.27 I Acid phosphatase homologues
KLFCKHPL_00338 2.8e-168 K LysR substrate binding domain
KLFCKHPL_00339 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLFCKHPL_00340 6.2e-43 1.3.5.4 C FAD binding domain
KLFCKHPL_00341 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
KLFCKHPL_00342 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KLFCKHPL_00343 9.7e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLFCKHPL_00344 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KLFCKHPL_00345 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KLFCKHPL_00346 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KLFCKHPL_00347 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KLFCKHPL_00348 6.4e-243 cydA 1.10.3.14 C ubiquinol oxidase
KLFCKHPL_00350 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KLFCKHPL_00351 7.5e-103 G Phosphoglycerate mutase family
KLFCKHPL_00352 2.1e-78 2.7.13.3 T GHKL domain
KLFCKHPL_00353 2.9e-79 K LytTr DNA-binding domain
KLFCKHPL_00354 8.7e-30 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLFCKHPL_00355 8.1e-126 S PAS domain
KLFCKHPL_00356 1.6e-11
KLFCKHPL_00357 2.7e-57
KLFCKHPL_00358 6.6e-56
KLFCKHPL_00359 4e-08
KLFCKHPL_00360 8.7e-139 S cog cog1373
KLFCKHPL_00361 9.7e-146 S haloacid dehalogenase-like hydrolase
KLFCKHPL_00362 2.5e-226 pbuG S permease
KLFCKHPL_00363 8.4e-25 G Peptidase_C39 like family
KLFCKHPL_00364 2.8e-162 M NlpC/P60 family
KLFCKHPL_00365 3.2e-90 G Peptidase_C39 like family
KLFCKHPL_00366 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
KLFCKHPL_00367 2.8e-77 P Cobalt transport protein
KLFCKHPL_00368 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
KLFCKHPL_00369 7.9e-174 K helix_turn_helix, arabinose operon control protein
KLFCKHPL_00370 8.3e-157 htpX O Belongs to the peptidase M48B family
KLFCKHPL_00371 5.1e-96 lemA S LemA family
KLFCKHPL_00372 1.6e-189 ybiR P Citrate transporter
KLFCKHPL_00373 2e-70 S Iron-sulphur cluster biosynthesis
KLFCKHPL_00374 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KLFCKHPL_00375 1.2e-17
KLFCKHPL_00376 1.1e-07 S Uncharacterised protein family (UPF0236)
KLFCKHPL_00377 4.5e-189 ydaM M Glycosyl transferase
KLFCKHPL_00378 4e-177 G Glycosyl hydrolases family 8
KLFCKHPL_00379 1e-119 yfbR S HD containing hydrolase-like enzyme
KLFCKHPL_00380 6.4e-159 L HNH nucleases
KLFCKHPL_00381 7.3e-148 S Protein of unknown function (DUF805)
KLFCKHPL_00382 3.4e-135 glnQ E ABC transporter, ATP-binding protein
KLFCKHPL_00383 1.3e-290 glnP P ABC transporter permease
KLFCKHPL_00384 8.9e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KLFCKHPL_00385 5.8e-64 yeaO S Protein of unknown function, DUF488
KLFCKHPL_00386 1.3e-124 terC P Integral membrane protein TerC family
KLFCKHPL_00387 2.5e-86 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
KLFCKHPL_00388 8.5e-133 cobB K SIR2 family
KLFCKHPL_00389 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLFCKHPL_00390 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KLFCKHPL_00391 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KLFCKHPL_00392 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KLFCKHPL_00393 2.5e-39 rpmE2 J Ribosomal protein L31
KLFCKHPL_00394 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
KLFCKHPL_00395 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
KLFCKHPL_00396 9.5e-297 ybeC E amino acid
KLFCKHPL_00397 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLFCKHPL_00398 2.1e-42
KLFCKHPL_00399 1.4e-51
KLFCKHPL_00400 2.2e-22
KLFCKHPL_00401 3.3e-140 repB EP Plasmid replication protein
KLFCKHPL_00402 2.2e-78 S helix_turn_helix, Deoxyribose operon repressor
KLFCKHPL_00403 8.1e-175 ulaG S Beta-lactamase superfamily domain
KLFCKHPL_00404 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KLFCKHPL_00405 5.3e-233 ulaA S PTS system sugar-specific permease component
KLFCKHPL_00406 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
KLFCKHPL_00407 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
KLFCKHPL_00408 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
KLFCKHPL_00409 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KLFCKHPL_00410 5.2e-68 L haloacid dehalogenase-like hydrolase
KLFCKHPL_00412 5.5e-30
KLFCKHPL_00413 4.3e-40 S Protein of unknown function (DUF2922)
KLFCKHPL_00414 5.2e-131 S SLAP domain
KLFCKHPL_00416 5.3e-41
KLFCKHPL_00417 1.2e-77 K DNA-templated transcription, initiation
KLFCKHPL_00418 1.1e-25
KLFCKHPL_00419 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLFCKHPL_00420 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLFCKHPL_00421 1.2e-103 S SLAP domain
KLFCKHPL_00423 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLFCKHPL_00424 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KLFCKHPL_00425 0.0 yjbQ P TrkA C-terminal domain protein
KLFCKHPL_00426 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KLFCKHPL_00427 7.8e-161 S Oxidoreductase family, NAD-binding Rossmann fold
KLFCKHPL_00428 2.1e-130
KLFCKHPL_00429 2.1e-116
KLFCKHPL_00430 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLFCKHPL_00431 1.4e-98 G Aldose 1-epimerase
KLFCKHPL_00432 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KLFCKHPL_00433 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KLFCKHPL_00434 0.0 XK27_08315 M Sulfatase
KLFCKHPL_00435 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KLFCKHPL_00436 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KLFCKHPL_00437 9.7e-52 S Iron-sulfur cluster assembly protein
KLFCKHPL_00438 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KLFCKHPL_00439 2.5e-47 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KLFCKHPL_00440 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KLFCKHPL_00441 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KLFCKHPL_00442 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLFCKHPL_00443 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLFCKHPL_00444 8.1e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KLFCKHPL_00445 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLFCKHPL_00446 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KLFCKHPL_00447 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLFCKHPL_00448 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KLFCKHPL_00449 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLFCKHPL_00450 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
KLFCKHPL_00451 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KLFCKHPL_00452 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLFCKHPL_00453 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLFCKHPL_00454 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KLFCKHPL_00455 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLFCKHPL_00456 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLFCKHPL_00457 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KLFCKHPL_00458 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLFCKHPL_00459 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLFCKHPL_00460 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLFCKHPL_00461 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLFCKHPL_00462 6.8e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLFCKHPL_00463 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLFCKHPL_00464 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLFCKHPL_00465 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KLFCKHPL_00466 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLFCKHPL_00467 2.3e-24 rpmD J Ribosomal protein L30
KLFCKHPL_00468 2.6e-71 rplO J Binds to the 23S rRNA
KLFCKHPL_00469 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KLFCKHPL_00470 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KLFCKHPL_00471 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLFCKHPL_00472 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KLFCKHPL_00473 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLFCKHPL_00474 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLFCKHPL_00475 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLFCKHPL_00476 1.4e-60 rplQ J Ribosomal protein L17
KLFCKHPL_00477 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLFCKHPL_00478 1e-156 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLFCKHPL_00479 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLFCKHPL_00480 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KLFCKHPL_00481 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLFCKHPL_00482 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
KLFCKHPL_00483 8.9e-133 L Phage integrase family
KLFCKHPL_00484 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
KLFCKHPL_00485 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
KLFCKHPL_00486 2.6e-280 thrC 4.2.3.1 E Threonine synthase
KLFCKHPL_00487 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KLFCKHPL_00488 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KLFCKHPL_00489 9.4e-118
KLFCKHPL_00490 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KLFCKHPL_00492 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLFCKHPL_00493 1.3e-116 S Peptidase family M23
KLFCKHPL_00494 1.2e-177 mbl D Cell shape determining protein MreB Mrl
KLFCKHPL_00495 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KLFCKHPL_00496 3.3e-33 S Protein of unknown function (DUF2969)
KLFCKHPL_00497 4.7e-216 rodA D Belongs to the SEDS family
KLFCKHPL_00498 1.8e-78 usp6 T universal stress protein
KLFCKHPL_00499 8.4e-39
KLFCKHPL_00500 2.2e-238 rarA L recombination factor protein RarA
KLFCKHPL_00501 1.3e-84 yueI S Protein of unknown function (DUF1694)
KLFCKHPL_00502 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLFCKHPL_00503 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KLFCKHPL_00504 1.4e-212 iscS2 2.8.1.7 E Aminotransferase class V
KLFCKHPL_00505 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLFCKHPL_00506 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KLFCKHPL_00507 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLFCKHPL_00508 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLFCKHPL_00509 3.5e-62 2.4.1.83 GT2 S GtrA-like protein
KLFCKHPL_00510 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KLFCKHPL_00511 1.5e-94 S Protein of unknown function (DUF3990)
KLFCKHPL_00512 6.5e-44
KLFCKHPL_00514 0.0 3.6.3.8 P P-type ATPase
KLFCKHPL_00515 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
KLFCKHPL_00516 2.5e-52
KLFCKHPL_00517 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KLFCKHPL_00518 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLFCKHPL_00519 5.7e-126 S Haloacid dehalogenase-like hydrolase
KLFCKHPL_00520 2.3e-108 radC L DNA repair protein
KLFCKHPL_00521 2.4e-176 mreB D cell shape determining protein MreB
KLFCKHPL_00522 2e-147 mreC M Involved in formation and maintenance of cell shape
KLFCKHPL_00523 2.7e-94 mreD
KLFCKHPL_00525 6.4e-54 S Protein of unknown function (DUF3397)
KLFCKHPL_00526 6.3e-78 mraZ K Belongs to the MraZ family
KLFCKHPL_00527 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KLFCKHPL_00528 1.8e-54 ftsL D Cell division protein FtsL
KLFCKHPL_00529 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KLFCKHPL_00530 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLFCKHPL_00531 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KLFCKHPL_00532 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLFCKHPL_00533 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KLFCKHPL_00534 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KLFCKHPL_00535 3.8e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KLFCKHPL_00536 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KLFCKHPL_00537 1.7e-45 yggT S YGGT family
KLFCKHPL_00538 5.7e-149 ylmH S S4 domain protein
KLFCKHPL_00539 2.8e-74 gpsB D DivIVA domain protein
KLFCKHPL_00540 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLFCKHPL_00541 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
KLFCKHPL_00542 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KLFCKHPL_00543 6.7e-37
KLFCKHPL_00544 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLFCKHPL_00545 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
KLFCKHPL_00546 5.4e-56 XK27_04120 S Putative amino acid metabolism
KLFCKHPL_00547 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KLFCKHPL_00548 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KLFCKHPL_00549 8.3e-106 S Repeat protein
KLFCKHPL_00550 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KLFCKHPL_00551 1.6e-294 L Nuclease-related domain
KLFCKHPL_00552 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KLFCKHPL_00553 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KLFCKHPL_00554 6.8e-116 dedA S SNARE-like domain protein
KLFCKHPL_00555 3.7e-100 S Protein of unknown function (DUF1461)
KLFCKHPL_00556 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KLFCKHPL_00557 2.1e-92 yutD S Protein of unknown function (DUF1027)
KLFCKHPL_00558 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KLFCKHPL_00559 4.3e-55
KLFCKHPL_00560 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KLFCKHPL_00561 3.2e-181 ccpA K catabolite control protein A
KLFCKHPL_00562 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KLFCKHPL_00563 1.3e-36
KLFCKHPL_00564 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KLFCKHPL_00565 3.7e-146 ykuT M mechanosensitive ion channel
KLFCKHPL_00566 6.9e-100 V ATPases associated with a variety of cellular activities
KLFCKHPL_00567 1.7e-139
KLFCKHPL_00568 5.4e-113
KLFCKHPL_00569 8.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KLFCKHPL_00570 4.2e-63 lmrB EGP Major facilitator Superfamily
KLFCKHPL_00571 2.5e-63 rbtT P Major Facilitator Superfamily
KLFCKHPL_00572 1.3e-141 yfeO P Voltage gated chloride channel
KLFCKHPL_00573 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
KLFCKHPL_00575 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
KLFCKHPL_00578 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLFCKHPL_00579 8.5e-260 qacA EGP Major facilitator Superfamily
KLFCKHPL_00581 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
KLFCKHPL_00582 1.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KLFCKHPL_00583 1.8e-119 S Putative esterase
KLFCKHPL_00584 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLFCKHPL_00585 3.4e-195 S Bacterial protein of unknown function (DUF871)
KLFCKHPL_00586 3.7e-130 ybbH_2 K rpiR family
KLFCKHPL_00587 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
KLFCKHPL_00588 4.2e-101 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KLFCKHPL_00589 2.5e-86 K GNAT family
KLFCKHPL_00590 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
KLFCKHPL_00591 4.7e-36 rbtT P Major Facilitator Superfamily
KLFCKHPL_00592 1.5e-152
KLFCKHPL_00593 3e-24
KLFCKHPL_00594 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KLFCKHPL_00595 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLFCKHPL_00596 2.2e-292 I Acyltransferase
KLFCKHPL_00597 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KLFCKHPL_00598 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KLFCKHPL_00599 1.2e-188 K Periplasmic binding protein-like domain
KLFCKHPL_00600 2e-106 K Transcriptional regulator, AbiEi antitoxin
KLFCKHPL_00601 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
KLFCKHPL_00602 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLFCKHPL_00603 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KLFCKHPL_00604 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KLFCKHPL_00605 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KLFCKHPL_00606 5.4e-165 lacR K Transcriptional regulator
KLFCKHPL_00607 8.9e-207 lacS G Transporter
KLFCKHPL_00608 5.7e-103 lacS G Transporter
KLFCKHPL_00609 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KLFCKHPL_00610 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KLFCKHPL_00611 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KLFCKHPL_00612 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KLFCKHPL_00614 4.3e-36
KLFCKHPL_00615 6.2e-288 P ABC transporter
KLFCKHPL_00616 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
KLFCKHPL_00617 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KLFCKHPL_00618 0.0 uup S ABC transporter, ATP-binding protein
KLFCKHPL_00619 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KLFCKHPL_00620 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KLFCKHPL_00621 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KLFCKHPL_00622 7.7e-22
KLFCKHPL_00623 9.3e-64 L PFAM IS66 Orf2 family protein
KLFCKHPL_00624 8.7e-34 S Transposase C of IS166 homeodomain
KLFCKHPL_00625 1.9e-245 L Transposase IS66 family
KLFCKHPL_00626 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLFCKHPL_00627 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KLFCKHPL_00628 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KLFCKHPL_00629 2.2e-85 S ECF transporter, substrate-specific component
KLFCKHPL_00630 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
KLFCKHPL_00631 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLFCKHPL_00632 1.8e-59 yabA L Involved in initiation control of chromosome replication
KLFCKHPL_00633 6.3e-154 holB 2.7.7.7 L DNA polymerase III
KLFCKHPL_00634 2e-52 yaaQ S Cyclic-di-AMP receptor
KLFCKHPL_00635 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLFCKHPL_00636 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KLFCKHPL_00637 4.4e-172 S Domain of unknown function (DUF389)
KLFCKHPL_00638 6e-86
KLFCKHPL_00639 5.9e-68 S Protein of unknown function (DUF3021)
KLFCKHPL_00640 2.5e-140 V ABC transporter
KLFCKHPL_00641 2e-106 S domain protein
KLFCKHPL_00642 3.7e-102 L Integrase
KLFCKHPL_00643 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
KLFCKHPL_00644 1.3e-30
KLFCKHPL_00645 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
KLFCKHPL_00646 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KLFCKHPL_00647 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KLFCKHPL_00648 3.5e-71 yqeY S YqeY-like protein
KLFCKHPL_00649 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
KLFCKHPL_00650 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLFCKHPL_00651 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KLFCKHPL_00652 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
KLFCKHPL_00653 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KLFCKHPL_00654 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KLFCKHPL_00655 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KLFCKHPL_00656 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KLFCKHPL_00657 1.4e-127 S Peptidase family M23
KLFCKHPL_00658 4.8e-81 mutT 3.6.1.55 F NUDIX domain
KLFCKHPL_00659 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KLFCKHPL_00660 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLFCKHPL_00661 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KLFCKHPL_00662 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
KLFCKHPL_00663 9.6e-124 skfE V ATPases associated with a variety of cellular activities
KLFCKHPL_00664 4.5e-141
KLFCKHPL_00665 5.1e-137
KLFCKHPL_00666 6.7e-145
KLFCKHPL_00667 1.4e-26
KLFCKHPL_00668 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KLFCKHPL_00669 7.5e-143
KLFCKHPL_00670 9.7e-169
KLFCKHPL_00671 6e-29 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
KLFCKHPL_00672 1.6e-227 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
KLFCKHPL_00673 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
KLFCKHPL_00674 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KLFCKHPL_00675 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KLFCKHPL_00676 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KLFCKHPL_00677 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
KLFCKHPL_00678 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KLFCKHPL_00679 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KLFCKHPL_00680 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KLFCKHPL_00681 1.6e-147 sip L Belongs to the 'phage' integrase family
KLFCKHPL_00682 2.5e-13
KLFCKHPL_00686 6e-14
KLFCKHPL_00687 3e-59
KLFCKHPL_00689 2.8e-13 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00690 2e-20 cro K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00692 1.1e-90 S AntA/AntB antirepressor
KLFCKHPL_00697 7.2e-10
KLFCKHPL_00698 5e-07 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00700 7.7e-48
KLFCKHPL_00702 2.4e-59 S Protein of unknown function (DUF1071)
KLFCKHPL_00703 4e-33 S Conserved phage C-terminus (Phg_2220_C)
KLFCKHPL_00704 1.4e-51 dnaC L IstB-like ATP binding protein
KLFCKHPL_00710 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
KLFCKHPL_00711 2.1e-14
KLFCKHPL_00719 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
KLFCKHPL_00720 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
KLFCKHPL_00721 1.5e-28 L Terminase small subunit
KLFCKHPL_00722 1.8e-230 S Terminase-like family
KLFCKHPL_00723 7e-142 S Protein of unknown function (DUF1073)
KLFCKHPL_00724 1e-97 S Phage Mu protein F like protein
KLFCKHPL_00725 1.1e-07 S Lysin motif
KLFCKHPL_00726 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
KLFCKHPL_00727 1.6e-58
KLFCKHPL_00728 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
KLFCKHPL_00729 2.1e-30 S Protein of unknown function (DUF4054)
KLFCKHPL_00730 1.5e-75
KLFCKHPL_00731 2.9e-45
KLFCKHPL_00732 8e-57
KLFCKHPL_00733 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
KLFCKHPL_00734 4e-56
KLFCKHPL_00735 9e-27
KLFCKHPL_00737 0.0 3.4.14.13 M Phage tail tape measure protein TP901
KLFCKHPL_00738 1.2e-58 M LysM domain
KLFCKHPL_00739 2.1e-46
KLFCKHPL_00740 5.7e-104
KLFCKHPL_00741 1.2e-48
KLFCKHPL_00742 9.5e-33
KLFCKHPL_00743 1.7e-125 Z012_12235 S Baseplate J-like protein
KLFCKHPL_00744 1.1e-08
KLFCKHPL_00745 1.6e-36
KLFCKHPL_00751 7.1e-38
KLFCKHPL_00752 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
KLFCKHPL_00753 1.1e-07
KLFCKHPL_00755 7.9e-19
KLFCKHPL_00756 5e-29
KLFCKHPL_00757 2.1e-173 M Glycosyl hydrolases family 25
KLFCKHPL_00758 9.2e-14
KLFCKHPL_00759 3e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KLFCKHPL_00760 9.2e-89 ypmB S Protein conserved in bacteria
KLFCKHPL_00761 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KLFCKHPL_00762 1.3e-114 dnaD L DnaD domain protein
KLFCKHPL_00763 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLFCKHPL_00764 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KLFCKHPL_00765 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KLFCKHPL_00766 1e-107 ypsA S Belongs to the UPF0398 family
KLFCKHPL_00767 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KLFCKHPL_00768 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KLFCKHPL_00769 1e-242 cpdA S Calcineurin-like phosphoesterase
KLFCKHPL_00770 3.4e-79
KLFCKHPL_00771 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
KLFCKHPL_00772 7.3e-126 S Alpha/beta hydrolase family
KLFCKHPL_00773 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
KLFCKHPL_00774 4.4e-140 ypuA S Protein of unknown function (DUF1002)
KLFCKHPL_00775 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLFCKHPL_00776 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
KLFCKHPL_00777 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLFCKHPL_00778 9.3e-86
KLFCKHPL_00779 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KLFCKHPL_00780 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KLFCKHPL_00781 2.6e-35 yaaA S S4 domain protein YaaA
KLFCKHPL_00782 4e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLFCKHPL_00783 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLFCKHPL_00784 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLFCKHPL_00785 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
KLFCKHPL_00786 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLFCKHPL_00787 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KLFCKHPL_00788 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KLFCKHPL_00789 5.7e-69 rplI J Binds to the 23S rRNA
KLFCKHPL_00790 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KLFCKHPL_00791 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
KLFCKHPL_00792 3.7e-168 degV S DegV family
KLFCKHPL_00793 4.2e-135 V ABC transporter transmembrane region
KLFCKHPL_00794 3.3e-166 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KLFCKHPL_00796 1.4e-16
KLFCKHPL_00797 4.7e-227 I Protein of unknown function (DUF2974)
KLFCKHPL_00798 9.2e-119 yhiD S MgtC family
KLFCKHPL_00800 3.9e-131 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00801 1.3e-31
KLFCKHPL_00802 7e-87 gtcA S Teichoic acid glycosylation protein
KLFCKHPL_00803 4.1e-80 fld C Flavodoxin
KLFCKHPL_00804 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
KLFCKHPL_00805 3.6e-163 yihY S Belongs to the UPF0761 family
KLFCKHPL_00806 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KLFCKHPL_00807 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KLFCKHPL_00808 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KLFCKHPL_00809 1.4e-118 D Alpha beta
KLFCKHPL_00810 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLFCKHPL_00811 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
KLFCKHPL_00812 1.6e-85
KLFCKHPL_00813 2.7e-74
KLFCKHPL_00814 1.4e-140 hlyX S Transporter associated domain
KLFCKHPL_00815 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KLFCKHPL_00816 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
KLFCKHPL_00817 0.0 clpE O Belongs to the ClpA ClpB family
KLFCKHPL_00818 7.4e-40 yabO J S4 domain protein
KLFCKHPL_00819 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLFCKHPL_00820 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KLFCKHPL_00821 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLFCKHPL_00822 3.4e-129 S (CBS) domain
KLFCKHPL_00823 1.8e-163
KLFCKHPL_00824 7.8e-26 K Acetyltransferase (GNAT) domain
KLFCKHPL_00826 0.0 ydgH S MMPL family
KLFCKHPL_00827 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
KLFCKHPL_00828 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
KLFCKHPL_00829 1.8e-154 corA P CorA-like Mg2+ transporter protein
KLFCKHPL_00830 2.3e-240 G Bacterial extracellular solute-binding protein
KLFCKHPL_00831 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
KLFCKHPL_00832 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
KLFCKHPL_00833 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
KLFCKHPL_00834 1.9e-203 malK P ATPases associated with a variety of cellular activities
KLFCKHPL_00835 1.3e-281 pipD E Dipeptidase
KLFCKHPL_00836 1.9e-158 endA F DNA RNA non-specific endonuclease
KLFCKHPL_00837 8e-182 dnaQ 2.7.7.7 L EXOIII
KLFCKHPL_00838 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KLFCKHPL_00839 3e-116 yviA S Protein of unknown function (DUF421)
KLFCKHPL_00840 1.1e-56 S Protein of unknown function (DUF3290)
KLFCKHPL_00841 0.0 fhaB M Rib/alpha-like repeat
KLFCKHPL_00842 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
KLFCKHPL_00843 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KLFCKHPL_00844 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KLFCKHPL_00845 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KLFCKHPL_00846 6.8e-209 msmX P Belongs to the ABC transporter superfamily
KLFCKHPL_00847 5e-213 malE G Bacterial extracellular solute-binding protein
KLFCKHPL_00848 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
KLFCKHPL_00849 3.3e-147 malG P ABC transporter permease
KLFCKHPL_00850 4.3e-67 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_00853 4.8e-28
KLFCKHPL_00854 4.7e-159 D nuclear chromosome segregation
KLFCKHPL_00855 1.2e-105 G Phosphoglycerate mutase family
KLFCKHPL_00856 2.6e-89 G Histidine phosphatase superfamily (branch 1)
KLFCKHPL_00857 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
KLFCKHPL_00858 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KLFCKHPL_00860 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KLFCKHPL_00862 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KLFCKHPL_00863 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
KLFCKHPL_00864 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KLFCKHPL_00865 4.4e-144 K SIS domain
KLFCKHPL_00866 6.7e-228 slpX S SLAP domain
KLFCKHPL_00867 1.3e-22 3.6.4.12 S transposase or invertase
KLFCKHPL_00868 6.6e-11
KLFCKHPL_00869 3.2e-240 npr 1.11.1.1 C NADH oxidase
KLFCKHPL_00872 4.4e-239 oppA2 E ABC transporter, substratebinding protein
KLFCKHPL_00873 3.4e-45 oppA2 E ABC transporter, substratebinding protein
KLFCKHPL_00874 3.3e-179
KLFCKHPL_00875 4.6e-123 gntR1 K UTRA
KLFCKHPL_00876 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
KLFCKHPL_00877 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KLFCKHPL_00878 1.7e-204 csaB M Glycosyl transferases group 1
KLFCKHPL_00879 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLFCKHPL_00880 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KLFCKHPL_00881 1.4e-204 tnpB L Putative transposase DNA-binding domain
KLFCKHPL_00882 0.0 pacL 3.6.3.8 P P-type ATPase
KLFCKHPL_00883 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KLFCKHPL_00884 3e-257 epsU S Polysaccharide biosynthesis protein
KLFCKHPL_00885 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
KLFCKHPL_00886 4.1e-83 ydcK S Belongs to the SprT family
KLFCKHPL_00888 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
KLFCKHPL_00889 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KLFCKHPL_00890 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLFCKHPL_00891 5.8e-203 camS S sex pheromone
KLFCKHPL_00892 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLFCKHPL_00893 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KLFCKHPL_00894 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLFCKHPL_00895 2.7e-171 yegS 2.7.1.107 G Lipid kinase
KLFCKHPL_00896 4.3e-108 ybhL S Belongs to the BI1 family
KLFCKHPL_00897 2.6e-57
KLFCKHPL_00898 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
KLFCKHPL_00899 2.8e-244 nhaC C Na H antiporter NhaC
KLFCKHPL_00900 6.3e-201 pbpX V Beta-lactamase
KLFCKHPL_00901 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLFCKHPL_00902 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
KLFCKHPL_00907 1.9e-259 emrY EGP Major facilitator Superfamily
KLFCKHPL_00908 2e-91 yxdD K Bacterial regulatory proteins, tetR family
KLFCKHPL_00909 0.0 4.2.1.53 S Myosin-crossreactive antigen
KLFCKHPL_00910 5.5e-148 S cog cog1373
KLFCKHPL_00911 1.4e-83 K FR47-like protein
KLFCKHPL_00912 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KLFCKHPL_00913 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLFCKHPL_00914 2.2e-165 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KLFCKHPL_00915 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLFCKHPL_00916 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KLFCKHPL_00917 1.8e-62 yabR J S1 RNA binding domain
KLFCKHPL_00918 6.8e-60 divIC D Septum formation initiator
KLFCKHPL_00919 9.7e-65 yagE E amino acid
KLFCKHPL_00920 8.4e-128 yagE E Amino acid permease
KLFCKHPL_00921 4.3e-86 3.4.21.96 S SLAP domain
KLFCKHPL_00922 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KLFCKHPL_00923 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KLFCKHPL_00924 1.2e-107 hlyIII S protein, hemolysin III
KLFCKHPL_00925 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
KLFCKHPL_00926 7.1e-36 yozE S Belongs to the UPF0346 family
KLFCKHPL_00927 1.1e-66 yjcE P NhaP-type Na H and K H
KLFCKHPL_00928 1.5e-40 yjcE P Sodium proton antiporter
KLFCKHPL_00929 1.9e-94 yjcE P Sodium proton antiporter
KLFCKHPL_00930 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KLFCKHPL_00931 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLFCKHPL_00932 5.8e-152 dprA LU DNA protecting protein DprA
KLFCKHPL_00933 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLFCKHPL_00934 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KLFCKHPL_00935 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
KLFCKHPL_00936 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KLFCKHPL_00937 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KLFCKHPL_00938 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
KLFCKHPL_00939 1.4e-86 C Aldo keto reductase
KLFCKHPL_00940 3.8e-48 M LysM domain protein
KLFCKHPL_00941 2.9e-15 M LysM domain protein
KLFCKHPL_00942 3.9e-33 I Carboxylesterase family
KLFCKHPL_00943 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
KLFCKHPL_00944 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
KLFCKHPL_00945 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
KLFCKHPL_00946 1.7e-148 S haloacid dehalogenase-like hydrolase
KLFCKHPL_00947 7e-50
KLFCKHPL_00948 1.9e-37
KLFCKHPL_00949 1.2e-63 S Alpha beta hydrolase
KLFCKHPL_00950 1e-23 S Alpha beta hydrolase
KLFCKHPL_00951 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KLFCKHPL_00952 1.4e-37 S Putative adhesin
KLFCKHPL_00953 3.7e-261 V ABC transporter transmembrane region
KLFCKHPL_00954 1.1e-139
KLFCKHPL_00955 3.7e-20
KLFCKHPL_00956 9.4e-132 comFC S Competence protein
KLFCKHPL_00957 4.7e-246 comFA L Helicase C-terminal domain protein
KLFCKHPL_00958 2.5e-118 yvyE 3.4.13.9 S YigZ family
KLFCKHPL_00959 1.9e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
KLFCKHPL_00960 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
KLFCKHPL_00961 8.5e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLFCKHPL_00962 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLFCKHPL_00963 5.2e-97 ymfM S Helix-turn-helix domain
KLFCKHPL_00964 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
KLFCKHPL_00965 1.9e-236 S Peptidase M16
KLFCKHPL_00966 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
KLFCKHPL_00967 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KLFCKHPL_00968 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
KLFCKHPL_00969 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KLFCKHPL_00970 2.6e-214 yubA S AI-2E family transporter
KLFCKHPL_00971 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KLFCKHPL_00972 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KLFCKHPL_00974 5.7e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
KLFCKHPL_00975 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
KLFCKHPL_00976 3.4e-42 S RloB-like protein
KLFCKHPL_00977 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
KLFCKHPL_00978 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
KLFCKHPL_00979 0.0 S SLAP domain
KLFCKHPL_00981 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
KLFCKHPL_00982 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
KLFCKHPL_00983 1.5e-239 G Bacterial extracellular solute-binding protein
KLFCKHPL_00984 5.7e-18
KLFCKHPL_00985 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
KLFCKHPL_00986 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KLFCKHPL_00987 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KLFCKHPL_00988 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KLFCKHPL_00989 1.2e-161 phnD P Phosphonate ABC transporter
KLFCKHPL_00991 8.8e-84 uspA T universal stress protein
KLFCKHPL_00992 8.4e-56 S Domain of unknown function (DUF4767)
KLFCKHPL_00993 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KLFCKHPL_00994 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
KLFCKHPL_00995 3.2e-101 3.6.1.27 I Acid phosphatase homologues
KLFCKHPL_00996 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLFCKHPL_00998 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLFCKHPL_00999 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
KLFCKHPL_01000 1.3e-61 M Glycosyl hydrolases family 25
KLFCKHPL_01001 2.6e-61 M Glycosyl hydrolases family 25
KLFCKHPL_01002 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KLFCKHPL_01003 3.5e-175 S Cysteine-rich secretory protein family
KLFCKHPL_01004 1.6e-41
KLFCKHPL_01005 2.6e-118 M NlpC/P60 family
KLFCKHPL_01006 1.4e-136 M NlpC P60 family protein
KLFCKHPL_01007 5e-88 M NlpC/P60 family
KLFCKHPL_01008 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
KLFCKHPL_01009 3.9e-42
KLFCKHPL_01010 2.9e-279 S O-antigen ligase like membrane protein
KLFCKHPL_01011 3.3e-112
KLFCKHPL_01012 4.7e-221 tnpB L Putative transposase DNA-binding domain
KLFCKHPL_01013 5.5e-77 nrdI F NrdI Flavodoxin like
KLFCKHPL_01014 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLFCKHPL_01015 2.5e-68
KLFCKHPL_01016 9.1e-112 yvpB S Peptidase_C39 like family
KLFCKHPL_01017 1.1e-83 S Threonine/Serine exporter, ThrE
KLFCKHPL_01018 2.4e-136 thrE S Putative threonine/serine exporter
KLFCKHPL_01019 8.9e-292 S ABC transporter
KLFCKHPL_01020 8.3e-58
KLFCKHPL_01021 5e-72 rimL J Acetyltransferase (GNAT) domain
KLFCKHPL_01022 1.4e-34
KLFCKHPL_01023 1.2e-30
KLFCKHPL_01024 1.8e-111 S Protein of unknown function (DUF554)
KLFCKHPL_01025 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KLFCKHPL_01026 0.0 pepF E oligoendopeptidase F
KLFCKHPL_01027 2.9e-31
KLFCKHPL_01028 1.3e-69 doc S Prophage maintenance system killer protein
KLFCKHPL_01031 4.6e-27 S Enterocin A Immunity
KLFCKHPL_01032 1.7e-22 blpT
KLFCKHPL_01033 5.9e-37 M domain protein
KLFCKHPL_01034 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KLFCKHPL_01035 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
KLFCKHPL_01036 8.5e-60
KLFCKHPL_01037 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLFCKHPL_01038 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLFCKHPL_01039 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KLFCKHPL_01040 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KLFCKHPL_01041 1.2e-222 patA 2.6.1.1 E Aminotransferase
KLFCKHPL_01042 3e-53 cvpA S Colicin V production protein
KLFCKHPL_01044 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KLFCKHPL_01045 6e-151 3.1.3.48 T Tyrosine phosphatase family
KLFCKHPL_01046 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
KLFCKHPL_01047 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
KLFCKHPL_01048 2.4e-110 K WHG domain
KLFCKHPL_01049 3e-37
KLFCKHPL_01050 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KLFCKHPL_01051 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KLFCKHPL_01052 6.7e-98 M ErfK YbiS YcfS YnhG
KLFCKHPL_01053 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KLFCKHPL_01054 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLFCKHPL_01056 4.7e-46 pspC KT PspC domain
KLFCKHPL_01057 3.3e-237 L COG2963 Transposase and inactivated derivatives
KLFCKHPL_01058 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLFCKHPL_01059 3.8e-99 S Tetratricopeptide repeat protein
KLFCKHPL_01060 1.4e-75 S Tetratricopeptide repeat protein
KLFCKHPL_01061 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLFCKHPL_01062 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KLFCKHPL_01063 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
KLFCKHPL_01064 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KLFCKHPL_01065 2.7e-18 M Lysin motif
KLFCKHPL_01066 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KLFCKHPL_01067 9e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLFCKHPL_01068 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KLFCKHPL_01069 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KLFCKHPL_01070 8.1e-54 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLFCKHPL_01071 2.9e-165 xerD D recombinase XerD
KLFCKHPL_01072 1e-167 cvfB S S1 domain
KLFCKHPL_01073 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KLFCKHPL_01074 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KLFCKHPL_01075 0.0 dnaE 2.7.7.7 L DNA polymerase
KLFCKHPL_01076 2.3e-23 S Protein of unknown function (DUF2929)
KLFCKHPL_01077 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KLFCKHPL_01078 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KLFCKHPL_01079 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
KLFCKHPL_01080 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
KLFCKHPL_01081 2.5e-264 3.6.3.6 P Cation transporter/ATPase, N-terminus
KLFCKHPL_01082 1.9e-19
KLFCKHPL_01084 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLFCKHPL_01085 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KLFCKHPL_01086 1.1e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KLFCKHPL_01087 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
KLFCKHPL_01088 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KLFCKHPL_01089 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLFCKHPL_01090 1.7e-184 G Transmembrane secretion effector
KLFCKHPL_01091 6.1e-136 V ABC transporter transmembrane region
KLFCKHPL_01092 5.1e-221 L transposase, IS605 OrfB family
KLFCKHPL_01093 1.1e-75 V ABC transporter transmembrane region
KLFCKHPL_01094 6.5e-64 L RelB antitoxin
KLFCKHPL_01095 2.1e-131 cobQ S glutamine amidotransferase
KLFCKHPL_01096 1.8e-81 M NlpC/P60 family
KLFCKHPL_01099 2.6e-155
KLFCKHPL_01100 7.8e-38
KLFCKHPL_01101 2e-32
KLFCKHPL_01102 6.2e-163 EG EamA-like transporter family
KLFCKHPL_01103 5e-165 EG EamA-like transporter family
KLFCKHPL_01104 1.2e-139 yicL EG EamA-like transporter family
KLFCKHPL_01105 4.3e-107
KLFCKHPL_01106 1.1e-110
KLFCKHPL_01107 5.8e-186 XK27_05540 S DUF218 domain
KLFCKHPL_01108 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
KLFCKHPL_01109 4.7e-85
KLFCKHPL_01110 3.9e-57
KLFCKHPL_01111 4.7e-25 S Protein conserved in bacteria
KLFCKHPL_01112 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
KLFCKHPL_01113 2e-234 mepA V MATE efflux family protein
KLFCKHPL_01114 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
KLFCKHPL_01115 1.8e-58 S Putative adhesin
KLFCKHPL_01116 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KLFCKHPL_01117 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
KLFCKHPL_01118 1.1e-83 dps P Belongs to the Dps family
KLFCKHPL_01119 2e-178 MA20_14895 S Conserved hypothetical protein 698
KLFCKHPL_01121 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KLFCKHPL_01122 9.2e-262 emrY EGP Major facilitator Superfamily
KLFCKHPL_01123 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KLFCKHPL_01124 7.6e-239 pyrP F Permease
KLFCKHPL_01125 6e-21 K Putative DNA-binding domain
KLFCKHPL_01126 1.2e-241 S response to antibiotic
KLFCKHPL_01127 4.9e-125
KLFCKHPL_01128 0.0 3.6.3.8 P P-type ATPase
KLFCKHPL_01129 8.7e-66 2.7.1.191 G PTS system fructose IIA component
KLFCKHPL_01130 4.4e-43
KLFCKHPL_01131 5.9e-09
KLFCKHPL_01132 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
KLFCKHPL_01133 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
KLFCKHPL_01134 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
KLFCKHPL_01135 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
KLFCKHPL_01136 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
KLFCKHPL_01137 3.4e-27
KLFCKHPL_01138 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
KLFCKHPL_01139 5.4e-53 hipB K sequence-specific DNA binding
KLFCKHPL_01140 4.8e-42 S SnoaL-like domain
KLFCKHPL_01141 0.0 L PLD-like domain
KLFCKHPL_01142 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KLFCKHPL_01143 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
KLFCKHPL_01144 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KLFCKHPL_01145 1.7e-284 E Amino acid permease
KLFCKHPL_01146 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
KLFCKHPL_01147 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
KLFCKHPL_01148 1.4e-115 mmuP E amino acid
KLFCKHPL_01149 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KLFCKHPL_01150 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLFCKHPL_01151 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLFCKHPL_01152 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
KLFCKHPL_01154 2.9e-23
KLFCKHPL_01155 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLFCKHPL_01156 0.0 L AAA domain
KLFCKHPL_01157 1e-226 yhaO L Ser Thr phosphatase family protein
KLFCKHPL_01158 7.2e-56 yheA S Belongs to the UPF0342 family
KLFCKHPL_01159 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLFCKHPL_01160 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLFCKHPL_01161 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KLFCKHPL_01162 1.1e-152 ydjP I Alpha/beta hydrolase family
KLFCKHPL_01163 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KLFCKHPL_01164 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
KLFCKHPL_01165 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
KLFCKHPL_01166 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
KLFCKHPL_01167 9.3e-72 yeaL S Protein of unknown function (DUF441)
KLFCKHPL_01168 3.5e-21
KLFCKHPL_01169 3.6e-146 cbiQ P cobalt transport
KLFCKHPL_01170 0.0 ykoD P ABC transporter, ATP-binding protein
KLFCKHPL_01171 1.5e-95 S UPF0397 protein
KLFCKHPL_01172 2.9e-66 S Domain of unknown function DUF1828
KLFCKHPL_01173 5.5e-09
KLFCKHPL_01174 1.5e-50
KLFCKHPL_01175 2.6e-177 citR K Putative sugar-binding domain
KLFCKHPL_01176 6.2e-249 yjjP S Putative threonine/serine exporter
KLFCKHPL_01177 1.5e-102 GM NmrA-like family
KLFCKHPL_01178 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLFCKHPL_01179 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KLFCKHPL_01180 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KLFCKHPL_01181 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KLFCKHPL_01182 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KLFCKHPL_01183 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KLFCKHPL_01184 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KLFCKHPL_01185 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KLFCKHPL_01186 3.7e-250 lctP C L-lactate permease
KLFCKHPL_01187 3.1e-148 glcU U sugar transport
KLFCKHPL_01188 7.1e-46
KLFCKHPL_01189 2.9e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KLFCKHPL_01190 4e-57 K Helix-turn-helix domain
KLFCKHPL_01191 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLFCKHPL_01192 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
KLFCKHPL_01193 5.6e-183 K Transcriptional regulator
KLFCKHPL_01194 5.8e-78 M LysM domain protein
KLFCKHPL_01195 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLFCKHPL_01196 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLFCKHPL_01197 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLFCKHPL_01198 6.2e-12
KLFCKHPL_01199 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
KLFCKHPL_01200 2.3e-30
KLFCKHPL_01202 2.9e-69 S Iron-sulphur cluster biosynthesis
KLFCKHPL_01203 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
KLFCKHPL_01204 6.2e-59 psiE S Phosphate-starvation-inducible E
KLFCKHPL_01206 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KLFCKHPL_01207 4.3e-228 amtB P ammonium transporter
KLFCKHPL_01208 1.4e-60
KLFCKHPL_01209 0.0 lhr L DEAD DEAH box helicase
KLFCKHPL_01210 1.4e-245 P P-loop Domain of unknown function (DUF2791)
KLFCKHPL_01211 2.6e-138 S TerB-C domain
KLFCKHPL_01212 2.4e-128 S cog cog1373
KLFCKHPL_01213 1.4e-109 yniG EGP Major facilitator Superfamily
KLFCKHPL_01214 5.4e-237 L transposase, IS605 OrfB family
KLFCKHPL_01215 4.5e-76 yniG EGP Major facilitator Superfamily
KLFCKHPL_01216 4.9e-35
KLFCKHPL_01218 1.3e-42
KLFCKHPL_01219 1.9e-75 M LysM domain
KLFCKHPL_01220 9.7e-83 S An automated process has identified a potential problem with this gene model
KLFCKHPL_01221 1e-137 S Protein of unknown function (DUF3100)
KLFCKHPL_01222 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
KLFCKHPL_01223 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
KLFCKHPL_01224 0.0 oppA E ABC transporter
KLFCKHPL_01225 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
KLFCKHPL_01226 0.0 mco Q Multicopper oxidase
KLFCKHPL_01227 1.9e-25
KLFCKHPL_01228 7.1e-158 metQ1 P Belongs to the nlpA lipoprotein family
KLFCKHPL_01229 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
KLFCKHPL_01230 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLFCKHPL_01231 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLFCKHPL_01232 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLFCKHPL_01233 1e-156 cjaA ET ABC transporter substrate-binding protein
KLFCKHPL_01234 1.5e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLFCKHPL_01235 5.3e-116 P ABC transporter permease
KLFCKHPL_01236 9.1e-54 papP P ABC transporter, permease protein
KLFCKHPL_01237 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
KLFCKHPL_01238 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
KLFCKHPL_01239 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
KLFCKHPL_01240 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
KLFCKHPL_01241 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLFCKHPL_01242 7.5e-100 J Acetyltransferase (GNAT) domain
KLFCKHPL_01243 1.4e-110 yjbF S SNARE associated Golgi protein
KLFCKHPL_01244 0.0 S SH3-like domain
KLFCKHPL_01245 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLFCKHPL_01246 2.1e-171 whiA K May be required for sporulation
KLFCKHPL_01247 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KLFCKHPL_01248 6.2e-165 rapZ S Displays ATPase and GTPase activities
KLFCKHPL_01249 4.1e-90 S Short repeat of unknown function (DUF308)
KLFCKHPL_01250 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KLFCKHPL_01251 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KLFCKHPL_01252 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KLFCKHPL_01253 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KLFCKHPL_01254 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KLFCKHPL_01255 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KLFCKHPL_01256 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KLFCKHPL_01257 5.1e-17
KLFCKHPL_01258 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KLFCKHPL_01259 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KLFCKHPL_01260 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLFCKHPL_01261 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
KLFCKHPL_01262 4.9e-111 ybbL S ABC transporter, ATP-binding protein
KLFCKHPL_01263 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
KLFCKHPL_01264 1.1e-243 yfnA E Amino Acid
KLFCKHPL_01265 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLFCKHPL_01266 9.2e-237 L transposase, IS605 OrfB family
KLFCKHPL_01267 2.1e-28 S Peptidase propeptide and YPEB domain
KLFCKHPL_01268 2.4e-60 ypaA S Protein of unknown function (DUF1304)
KLFCKHPL_01269 2.3e-309 oppA3 E ABC transporter, substratebinding protein
KLFCKHPL_01270 6e-46 L An automated process has identified a potential problem with this gene model
KLFCKHPL_01271 2.8e-48 S Peptidase propeptide and YPEB domain
KLFCKHPL_01272 6.5e-169 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KLFCKHPL_01273 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KLFCKHPL_01274 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
KLFCKHPL_01275 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
KLFCKHPL_01276 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
KLFCKHPL_01277 1.3e-273 pipD E Dipeptidase
KLFCKHPL_01278 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KLFCKHPL_01279 2.1e-175 hrtB V ABC transporter permease
KLFCKHPL_01280 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
KLFCKHPL_01281 3.5e-111 G phosphoglycerate mutase
KLFCKHPL_01282 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KLFCKHPL_01283 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
KLFCKHPL_01284 1e-30 S cog cog1373
KLFCKHPL_01285 1.4e-15 S cog cog1373
KLFCKHPL_01286 2e-129 hipB K Helix-turn-helix
KLFCKHPL_01287 2.7e-151 I alpha/beta hydrolase fold
KLFCKHPL_01288 2.2e-85 S PFAM Archaeal ATPase
KLFCKHPL_01289 5.7e-84 S PFAM Archaeal ATPase
KLFCKHPL_01290 7.7e-26
KLFCKHPL_01291 3.1e-71 2.5.1.74 H UbiA prenyltransferase family
KLFCKHPL_01292 4.3e-24 S SLAP domain
KLFCKHPL_01293 7.6e-25 S SLAP domain
KLFCKHPL_01294 1.3e-229 S Putative peptidoglycan binding domain
KLFCKHPL_01295 7.5e-95 S ECF-type riboflavin transporter, S component
KLFCKHPL_01296 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KLFCKHPL_01297 9.3e-204 pbpX1 V Beta-lactamase
KLFCKHPL_01298 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
KLFCKHPL_01299 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLFCKHPL_01300 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
KLFCKHPL_01301 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KLFCKHPL_01302 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLFCKHPL_01303 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLFCKHPL_01304 2e-157 S reductase
KLFCKHPL_01305 9.3e-35
KLFCKHPL_01306 4.4e-103 K Putative DNA-binding domain
KLFCKHPL_01307 8.8e-41 clcA P chloride
KLFCKHPL_01308 1.6e-60 clcA P chloride
KLFCKHPL_01309 4.7e-26 K FCD
KLFCKHPL_01310 4.7e-182 pepA E M42 glutamyl aminopeptidase
KLFCKHPL_01311 2.2e-311 ybiT S ABC transporter, ATP-binding protein
KLFCKHPL_01312 5.9e-174 S Aldo keto reductase
KLFCKHPL_01313 2.7e-138
KLFCKHPL_01314 2.8e-202 steT E amino acid
KLFCKHPL_01315 2.4e-26 steT E amino acid
KLFCKHPL_01316 8.6e-243 steT E amino acid
KLFCKHPL_01317 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
KLFCKHPL_01318 1.9e-147 glnH ET ABC transporter
KLFCKHPL_01319 1.4e-80 K Transcriptional regulator, MarR family
KLFCKHPL_01320 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
KLFCKHPL_01321 0.0 V ABC transporter transmembrane region
KLFCKHPL_01322 1.6e-100 S ABC-type cobalt transport system, permease component
KLFCKHPL_01323 1e-246 G MFS/sugar transport protein
KLFCKHPL_01324 1e-44 udk 2.7.1.48 F Zeta toxin
KLFCKHPL_01325 3.8e-46 udk 2.7.1.48 F Zeta toxin
KLFCKHPL_01326 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLFCKHPL_01327 1.2e-146 glnH ET ABC transporter substrate-binding protein
KLFCKHPL_01328 3.7e-90 gluC P ABC transporter permease
KLFCKHPL_01329 4.7e-109 glnP P ABC transporter permease
KLFCKHPL_01330 1.1e-164 S Protein of unknown function (DUF2974)
KLFCKHPL_01331 5.6e-86
KLFCKHPL_01332 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
KLFCKHPL_01333 1.3e-235 G Bacterial extracellular solute-binding protein
KLFCKHPL_01334 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
KLFCKHPL_01335 1e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLFCKHPL_01336 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KLFCKHPL_01337 0.0 kup P Transport of potassium into the cell
KLFCKHPL_01338 9.1e-175 rihB 3.2.2.1 F Nucleoside
KLFCKHPL_01339 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
KLFCKHPL_01340 1.2e-154 S hydrolase
KLFCKHPL_01341 2.5e-59 S Enterocin A Immunity
KLFCKHPL_01342 3.1e-136 glcR K DeoR C terminal sensor domain
KLFCKHPL_01343 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KLFCKHPL_01344 2e-160 rssA S Phospholipase, patatin family
KLFCKHPL_01345 5.4e-147 S hydrolase
KLFCKHPL_01346 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
KLFCKHPL_01347 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
KLFCKHPL_01348 1.6e-80
KLFCKHPL_01349 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KLFCKHPL_01350 2.1e-39
KLFCKHPL_01351 3.9e-119 C nitroreductase
KLFCKHPL_01352 1.7e-249 yhdP S Transporter associated domain
KLFCKHPL_01353 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLFCKHPL_01354 0.0 1.3.5.4 C FAD binding domain
KLFCKHPL_01355 3.9e-31 S Domain of unknown function DUF1829
KLFCKHPL_01356 1.1e-265
KLFCKHPL_01357 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
KLFCKHPL_01358 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KLFCKHPL_01359 3.9e-25
KLFCKHPL_01360 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
KLFCKHPL_01361 5.7e-135 ecsA V ABC transporter, ATP-binding protein
KLFCKHPL_01362 6.5e-221 ecsB U ABC transporter
KLFCKHPL_01363 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KLFCKHPL_01365 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KLFCKHPL_01366 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLFCKHPL_01367 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KLFCKHPL_01368 6.9e-218 mepA V MATE efflux family protein
KLFCKHPL_01369 1.8e-176 S SLAP domain
KLFCKHPL_01370 4.4e-283 M Peptidase family M1 domain
KLFCKHPL_01371 4.5e-188 S Bacteriocin helveticin-J
KLFCKHPL_01372 8e-51 L RelB antitoxin
KLFCKHPL_01373 7.4e-105 qmcA O prohibitin homologues
KLFCKHPL_01374 3.5e-25 qmcA O prohibitin homologues
KLFCKHPL_01375 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLFCKHPL_01376 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KLFCKHPL_01377 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KLFCKHPL_01378 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLFCKHPL_01379 5.1e-251 dnaB L Replication initiation and membrane attachment
KLFCKHPL_01380 2.1e-168 dnaI L Primosomal protein DnaI
KLFCKHPL_01381 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLFCKHPL_01382 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
KLFCKHPL_01383 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLFCKHPL_01384 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLFCKHPL_01385 1.2e-155 pstA P Phosphate transport system permease protein PstA
KLFCKHPL_01386 3.9e-163 pstC P probably responsible for the translocation of the substrate across the membrane
KLFCKHPL_01387 2.8e-157 pstS P Phosphate
KLFCKHPL_01388 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KLFCKHPL_01389 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLFCKHPL_01390 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
KLFCKHPL_01391 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KLFCKHPL_01392 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KLFCKHPL_01393 5.8e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLFCKHPL_01394 1.7e-34
KLFCKHPL_01395 5.5e-95 sigH K Belongs to the sigma-70 factor family
KLFCKHPL_01396 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLFCKHPL_01397 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KLFCKHPL_01398 2.9e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLFCKHPL_01399 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLFCKHPL_01400 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLFCKHPL_01401 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KLFCKHPL_01402 1.9e-52
KLFCKHPL_01403 3.9e-267 pepC 3.4.22.40 E Peptidase C1-like family
KLFCKHPL_01404 1.1e-183 S AAA domain
KLFCKHPL_01405 1.2e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLFCKHPL_01406 1.4e-23
KLFCKHPL_01407 7.3e-161 czcD P cation diffusion facilitator family transporter
KLFCKHPL_01408 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
KLFCKHPL_01409 6e-132 S membrane transporter protein
KLFCKHPL_01410 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KLFCKHPL_01411 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KLFCKHPL_01412 1.2e-49 S Protein of unknown function (DUF3021)
KLFCKHPL_01413 2.8e-65 K LytTr DNA-binding domain
KLFCKHPL_01414 1.2e-10
KLFCKHPL_01415 1.3e-55 K Acetyltransferase (GNAT) domain
KLFCKHPL_01416 1.9e-12 L Transposase
KLFCKHPL_01417 1.4e-16 L Transposase
KLFCKHPL_01418 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KLFCKHPL_01419 1.6e-310 oppA E ABC transporter, substratebinding protein
KLFCKHPL_01420 5e-301 oppA E ABC transporter, substratebinding protein
KLFCKHPL_01421 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLFCKHPL_01422 4.6e-257 pepC 3.4.22.40 E aminopeptidase
KLFCKHPL_01424 3.4e-53
KLFCKHPL_01425 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLFCKHPL_01426 8.4e-265 S Fibronectin type III domain
KLFCKHPL_01427 5.3e-80
KLFCKHPL_01428 2e-295 S SLAP domain
KLFCKHPL_01429 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLFCKHPL_01430 1.6e-171 2.7.1.2 GK ROK family
KLFCKHPL_01431 6.6e-44
KLFCKHPL_01432 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLFCKHPL_01433 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLFCKHPL_01434 4.8e-34 S reductase
KLFCKHPL_01435 4.4e-39 S reductase
KLFCKHPL_01436 2.7e-32 S reductase
KLFCKHPL_01437 6.4e-148 yxeH S hydrolase
KLFCKHPL_01438 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLFCKHPL_01439 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLFCKHPL_01440 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLFCKHPL_01441 2.3e-198 oppD P Belongs to the ABC transporter superfamily
KLFCKHPL_01442 1.9e-175 oppF P Belongs to the ABC transporter superfamily
KLFCKHPL_01443 5.2e-256 pepC 3.4.22.40 E aminopeptidase
KLFCKHPL_01444 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
KLFCKHPL_01445 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLFCKHPL_01446 7.9e-112
KLFCKHPL_01448 1.2e-111 E Belongs to the SOS response-associated peptidase family
KLFCKHPL_01449 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLFCKHPL_01450 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
KLFCKHPL_01451 2e-103 S TPM domain
KLFCKHPL_01452 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KLFCKHPL_01453 1e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KLFCKHPL_01454 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLFCKHPL_01455 1e-147 tatD L hydrolase, TatD family
KLFCKHPL_01456 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KLFCKHPL_01457 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KLFCKHPL_01458 4.5e-39 veg S Biofilm formation stimulator VEG
KLFCKHPL_01459 1.1e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KLFCKHPL_01460 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLFCKHPL_01462 1.6e-73 marR K Transcriptional regulator, MarR family
KLFCKHPL_01463 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KLFCKHPL_01464 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLFCKHPL_01465 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLFCKHPL_01466 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLFCKHPL_01467 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KLFCKHPL_01468 2.9e-107 IQ reductase
KLFCKHPL_01469 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KLFCKHPL_01470 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KLFCKHPL_01471 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KLFCKHPL_01472 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KLFCKHPL_01473 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KLFCKHPL_01474 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KLFCKHPL_01475 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KLFCKHPL_01476 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KLFCKHPL_01477 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLFCKHPL_01480 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
KLFCKHPL_01481 1.3e-273 E amino acid
KLFCKHPL_01482 0.0 L Helicase C-terminal domain protein
KLFCKHPL_01483 4.8e-205 pbpX1 V Beta-lactamase
KLFCKHPL_01484 5.1e-226 N Uncharacterized conserved protein (DUF2075)
KLFCKHPL_01485 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KLFCKHPL_01486 1.2e-299 I Protein of unknown function (DUF2974)
KLFCKHPL_01487 2.1e-194 pbpX1 V Beta-lactamase
KLFCKHPL_01488 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLFCKHPL_01489 2.7e-216 aspC 2.6.1.1 E Aminotransferase
KLFCKHPL_01490 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLFCKHPL_01491 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KLFCKHPL_01492 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KLFCKHPL_01493 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KLFCKHPL_01494 1.8e-245 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KLFCKHPL_01495 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
KLFCKHPL_01496 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KLFCKHPL_01497 3.4e-175 yjeM E Amino Acid
KLFCKHPL_01498 7.8e-39 yjeM E Amino Acid
KLFCKHPL_01499 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
KLFCKHPL_01500 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLFCKHPL_01501 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLFCKHPL_01502 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLFCKHPL_01503 1.3e-148
KLFCKHPL_01504 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLFCKHPL_01505 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLFCKHPL_01506 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
KLFCKHPL_01507 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
KLFCKHPL_01508 0.0 comEC S Competence protein ComEC
KLFCKHPL_01509 3.1e-79 comEA L Competence protein ComEA
KLFCKHPL_01510 2.4e-187 ylbL T Belongs to the peptidase S16 family
KLFCKHPL_01511 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLFCKHPL_01512 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KLFCKHPL_01513 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KLFCKHPL_01514 5.9e-211 ftsW D Belongs to the SEDS family
KLFCKHPL_01515 0.0 typA T GTP-binding protein TypA
KLFCKHPL_01516 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLFCKHPL_01517 3.5e-32 ykzG S Belongs to the UPF0356 family
KLFCKHPL_01518 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLFCKHPL_01519 1.4e-210 yttB EGP Major facilitator Superfamily
KLFCKHPL_01520 0.0 pepO 3.4.24.71 O Peptidase family M13
KLFCKHPL_01521 0.0 kup P Transport of potassium into the cell
KLFCKHPL_01522 7.3e-74
KLFCKHPL_01523 2.1e-45 S PFAM Archaeal ATPase
KLFCKHPL_01525 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KLFCKHPL_01526 5.9e-45
KLFCKHPL_01527 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
KLFCKHPL_01528 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KLFCKHPL_01529 3e-89 ntd 2.4.2.6 F Nucleoside
KLFCKHPL_01530 5.2e-08
KLFCKHPL_01531 5.4e-13
KLFCKHPL_01532 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KLFCKHPL_01533 0.0 G Belongs to the glycosyl hydrolase 31 family
KLFCKHPL_01534 8.7e-145 I alpha/beta hydrolase fold
KLFCKHPL_01535 4.9e-129 yibF S overlaps another CDS with the same product name
KLFCKHPL_01536 2.2e-202 yibE S overlaps another CDS with the same product name
KLFCKHPL_01537 1.4e-112
KLFCKHPL_01538 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KLFCKHPL_01539 6.4e-224 S Cysteine-rich secretory protein family
KLFCKHPL_01540 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLFCKHPL_01541 1.3e-258 glnPH2 P ABC transporter permease
KLFCKHPL_01542 2.8e-135
KLFCKHPL_01543 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
KLFCKHPL_01544 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLFCKHPL_01545 5.6e-36
KLFCKHPL_01546 1e-20 S Enterocin A Immunity
KLFCKHPL_01548 5.7e-43 2.4.1.33 V HlyD family secretion protein
KLFCKHPL_01549 9.9e-285 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLFCKHPL_01550 4.2e-92 S SNARE associated Golgi protein
KLFCKHPL_01551 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KLFCKHPL_01552 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLFCKHPL_01553 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLFCKHPL_01554 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
KLFCKHPL_01555 6.8e-110 yjbK S CYTH
KLFCKHPL_01556 4.6e-114 yjbH Q Thioredoxin
KLFCKHPL_01557 4e-13 coiA 3.6.4.12 S Competence protein
KLFCKHPL_01558 3.3e-132 coiA 3.6.4.12 S Competence protein
KLFCKHPL_01559 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KLFCKHPL_01560 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KLFCKHPL_01561 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLFCKHPL_01562 8.5e-41 ptsH G phosphocarrier protein HPR
KLFCKHPL_01563 5.3e-26
KLFCKHPL_01566 2.4e-36
KLFCKHPL_01567 4.9e-58 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KLFCKHPL_01568 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KLFCKHPL_01569 0.0 copA 3.6.3.54 P P-type ATPase
KLFCKHPL_01570 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KLFCKHPL_01571 1e-104
KLFCKHPL_01572 1.4e-52 EGP Sugar (and other) transporter
KLFCKHPL_01573 9.3e-147 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
KLFCKHPL_01574 0.0 mtlR K Mga helix-turn-helix domain
KLFCKHPL_01575 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KLFCKHPL_01576 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLFCKHPL_01577 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLFCKHPL_01578 6.8e-243 cycA E Amino acid permease
KLFCKHPL_01579 1.3e-85 maa S transferase hexapeptide repeat
KLFCKHPL_01580 3.3e-158 K Transcriptional regulator
KLFCKHPL_01581 1.1e-62 manO S Domain of unknown function (DUF956)
KLFCKHPL_01582 1e-173 manN G system, mannose fructose sorbose family IID component
KLFCKHPL_01583 1.7e-129 manY G PTS system
KLFCKHPL_01584 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KLFCKHPL_01585 8.8e-58 S Peptidase propeptide and YPEB domain
KLFCKHPL_01586 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLFCKHPL_01587 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
KLFCKHPL_01588 7.1e-98 E GDSL-like Lipase/Acylhydrolase
KLFCKHPL_01589 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
KLFCKHPL_01590 1.6e-143 aatB ET ABC transporter substrate-binding protein
KLFCKHPL_01591 1e-105 glnQ 3.6.3.21 E ABC transporter
KLFCKHPL_01592 1.5e-107 glnP P ABC transporter permease
KLFCKHPL_01593 0.0 helD 3.6.4.12 L DNA helicase
KLFCKHPL_01594 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KLFCKHPL_01595 1.4e-126 pgm3 G Phosphoglycerate mutase family
KLFCKHPL_01596 1.3e-284 lsa S ABC transporter
KLFCKHPL_01597 2.4e-44
KLFCKHPL_01598 6.9e-47 mdtG EGP Major facilitator Superfamily
KLFCKHPL_01599 1.7e-152 mdtG EGP Major facilitator Superfamily
KLFCKHPL_01600 1.3e-174
KLFCKHPL_01601 2.8e-47 lysM M LysM domain
KLFCKHPL_01602 0.0 pepN 3.4.11.2 E aminopeptidase
KLFCKHPL_01603 1.3e-250 dtpT U amino acid peptide transporter
KLFCKHPL_01604 1.2e-18 S Sugar efflux transporter for intercellular exchange
KLFCKHPL_01605 6.6e-70 XK27_02470 K LytTr DNA-binding domain
KLFCKHPL_01606 7.9e-92 liaI S membrane
KLFCKHPL_01607 4e-16
KLFCKHPL_01608 3.9e-186 S Putative peptidoglycan binding domain
KLFCKHPL_01609 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
KLFCKHPL_01610 9e-121
KLFCKHPL_01611 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KLFCKHPL_01612 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
KLFCKHPL_01613 1.4e-36 S Cytochrome B5
KLFCKHPL_01614 6e-168 arbZ I Phosphate acyltransferases
KLFCKHPL_01615 1.6e-182 arbY M Glycosyl transferase family 8
KLFCKHPL_01616 5e-184 arbY M Glycosyl transferase family 8
KLFCKHPL_01617 5e-156 arbx M Glycosyl transferase family 8
KLFCKHPL_01618 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
KLFCKHPL_01620 4.9e-34
KLFCKHPL_01622 4.8e-131 K response regulator
KLFCKHPL_01623 2.2e-305 vicK 2.7.13.3 T Histidine kinase
KLFCKHPL_01624 1.6e-257 yycH S YycH protein
KLFCKHPL_01625 3.4e-149 yycI S YycH protein
KLFCKHPL_01626 4.1e-147 vicX 3.1.26.11 S domain protein
KLFCKHPL_01627 1.6e-161 htrA 3.4.21.107 O serine protease
KLFCKHPL_01628 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLFCKHPL_01629 1.4e-34
KLFCKHPL_01630 3.6e-63
KLFCKHPL_01633 4.9e-118
KLFCKHPL_01634 3.8e-104 pncA Q Isochorismatase family
KLFCKHPL_01636 2e-35
KLFCKHPL_01637 0.0 snf 2.7.11.1 KL domain protein
KLFCKHPL_01638 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KLFCKHPL_01639 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLFCKHPL_01640 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLFCKHPL_01641 1e-48 S Metal binding domain of Ada
KLFCKHPL_01642 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
KLFCKHPL_01643 9e-137 lysR5 K LysR substrate binding domain
KLFCKHPL_01644 8.8e-234 arcA 3.5.3.6 E Arginine
KLFCKHPL_01645 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KLFCKHPL_01646 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
KLFCKHPL_01647 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KLFCKHPL_01648 2.3e-215 S Sterol carrier protein domain
KLFCKHPL_01649 1e-20
KLFCKHPL_01650 4.9e-108 K LysR substrate binding domain
KLFCKHPL_01651 9e-98
KLFCKHPL_01652 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
KLFCKHPL_01653 2.7e-36 yyaR K Acetyltransferase (GNAT) domain
KLFCKHPL_01654 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KLFCKHPL_01655 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KLFCKHPL_01656 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KLFCKHPL_01657 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KLFCKHPL_01658 8.6e-199 tnpB L Putative transposase DNA-binding domain
KLFCKHPL_01659 4.2e-84 yqeG S HAD phosphatase, family IIIA
KLFCKHPL_01660 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
KLFCKHPL_01661 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLFCKHPL_01662 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KLFCKHPL_01663 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KLFCKHPL_01664 4.6e-216 ylbM S Belongs to the UPF0348 family
KLFCKHPL_01665 4.7e-97 yceD S Uncharacterized ACR, COG1399
KLFCKHPL_01666 1.2e-126 K response regulator
KLFCKHPL_01667 1.3e-277 arlS 2.7.13.3 T Histidine kinase
KLFCKHPL_01668 1e-12
KLFCKHPL_01669 1.5e-97 S CAAX protease self-immunity
KLFCKHPL_01670 6.1e-224 S SLAP domain
KLFCKHPL_01671 5.7e-83 S Aminoacyl-tRNA editing domain
KLFCKHPL_01672 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLFCKHPL_01673 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KLFCKHPL_01674 2.2e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLFCKHPL_01675 4.5e-58 yodB K Transcriptional regulator, HxlR family
KLFCKHPL_01677 8.3e-24 papP P ABC transporter, permease protein
KLFCKHPL_01678 1.2e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KLFCKHPL_01679 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KLFCKHPL_01680 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLFCKHPL_01681 2.2e-120 lsa S ABC transporter
KLFCKHPL_01682 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KLFCKHPL_01683 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
KLFCKHPL_01684 5.6e-179 S PFAM Archaeal ATPase
KLFCKHPL_01685 2.4e-73 S cog cog1373
KLFCKHPL_01686 1.5e-230 XK27_04775 S PAS domain
KLFCKHPL_01687 1.3e-102 S Iron-sulfur cluster assembly protein
KLFCKHPL_01688 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLFCKHPL_01689 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KLFCKHPL_01690 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
KLFCKHPL_01691 0.0 asnB 6.3.5.4 E Asparagine synthase
KLFCKHPL_01692 1.3e-270 S Calcineurin-like phosphoesterase
KLFCKHPL_01693 3.9e-84
KLFCKHPL_01694 1.6e-105 tag 3.2.2.20 L glycosylase
KLFCKHPL_01695 4.5e-168 L COG3385 FOG Transposase and inactivated derivatives
KLFCKHPL_01696 8.2e-230 pbuG S permease
KLFCKHPL_01697 8.2e-140 cof S haloacid dehalogenase-like hydrolase
KLFCKHPL_01698 9.4e-72
KLFCKHPL_01699 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KLFCKHPL_01700 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KLFCKHPL_01701 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLFCKHPL_01703 1.6e-25 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_01704 1.2e-11
KLFCKHPL_01705 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
KLFCKHPL_01706 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KLFCKHPL_01707 4.5e-264 lctP C L-lactate permease
KLFCKHPL_01708 5e-129 znuB U ABC 3 transport family
KLFCKHPL_01709 1.6e-117 fhuC P ABC transporter
KLFCKHPL_01710 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
KLFCKHPL_01711 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
KLFCKHPL_01712 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
KLFCKHPL_01713 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KLFCKHPL_01714 1.8e-136 fruR K DeoR C terminal sensor domain
KLFCKHPL_01715 1.8e-218 natB CP ABC-2 family transporter protein
KLFCKHPL_01716 1.1e-164 natA S ABC transporter, ATP-binding protein
KLFCKHPL_01717 1.7e-67
KLFCKHPL_01718 2e-23
KLFCKHPL_01719 8.2e-31 yozG K Transcriptional regulator
KLFCKHPL_01720 3.7e-83
KLFCKHPL_01721 3e-21
KLFCKHPL_01724 3.8e-15 S Domain of Unknown Function with PDB structure (DUF3850)
KLFCKHPL_01726 2.9e-12
KLFCKHPL_01727 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KLFCKHPL_01728 1e-205 M Glycosyl hydrolases family 25
KLFCKHPL_01729 2.8e-157 cinI S Serine hydrolase (FSH1)
KLFCKHPL_01730 4.3e-298 S Predicted membrane protein (DUF2207)
KLFCKHPL_01731 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KLFCKHPL_01733 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
KLFCKHPL_01734 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KLFCKHPL_01735 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KLFCKHPL_01736 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KLFCKHPL_01737 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KLFCKHPL_01738 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLFCKHPL_01739 3.4e-71 yqhY S Asp23 family, cell envelope-related function
KLFCKHPL_01740 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLFCKHPL_01741 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KLFCKHPL_01742 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLFCKHPL_01743 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLFCKHPL_01744 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLFCKHPL_01745 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KLFCKHPL_01746 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
KLFCKHPL_01747 1.1e-77 6.3.3.2 S ASCH
KLFCKHPL_01748 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KLFCKHPL_01749 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KLFCKHPL_01750 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLFCKHPL_01751 2.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLFCKHPL_01752 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLFCKHPL_01753 1.1e-138 stp 3.1.3.16 T phosphatase
KLFCKHPL_01754 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KLFCKHPL_01755 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KLFCKHPL_01756 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KLFCKHPL_01757 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
KLFCKHPL_01758 1.4e-30
KLFCKHPL_01759 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KLFCKHPL_01760 1.5e-56 asp S Asp23 family, cell envelope-related function
KLFCKHPL_01761 7.6e-305 yloV S DAK2 domain fusion protein YloV
KLFCKHPL_01762 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KLFCKHPL_01763 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KLFCKHPL_01764 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLFCKHPL_01765 3.1e-192 oppD P Belongs to the ABC transporter superfamily
KLFCKHPL_01766 1.5e-170 oppF P Belongs to the ABC transporter superfamily
KLFCKHPL_01767 2.6e-172 oppB P ABC transporter permease
KLFCKHPL_01768 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
KLFCKHPL_01769 9.7e-46 oppA E ABC transporter substrate-binding protein
KLFCKHPL_01771 1.2e-134 EGP Major facilitator Superfamily
KLFCKHPL_01772 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
KLFCKHPL_01773 0.0 tetP J elongation factor G
KLFCKHPL_01774 3.5e-160 yvgN C Aldo keto reductase
KLFCKHPL_01775 2e-155 P CorA-like Mg2+ transporter protein
KLFCKHPL_01776 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KLFCKHPL_01777 4.9e-174 ABC-SBP S ABC transporter
KLFCKHPL_01778 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KLFCKHPL_01779 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
KLFCKHPL_01780 5.2e-248 G Major Facilitator
KLFCKHPL_01781 4.1e-18
KLFCKHPL_01782 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KLFCKHPL_01783 1.4e-176 K AI-2E family transporter
KLFCKHPL_01784 8.6e-97 oppA E ABC transporter substrate-binding protein
KLFCKHPL_01785 1.2e-232 oppA E ABC transporter substrate-binding protein
KLFCKHPL_01786 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KLFCKHPL_01787 7.2e-29 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S regulation of response to stimulus
KLFCKHPL_01788 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KLFCKHPL_01789 2.6e-146 S Putative ABC-transporter type IV
KLFCKHPL_01790 1.7e-07 S LPXTG cell wall anchor motif
KLFCKHPL_01791 1.5e-42 ybaT E Amino acid permease
KLFCKHPL_01792 2e-44 ybaT E Amino acid permease
KLFCKHPL_01794 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_01795 1.4e-22 S CAAX protease self-immunity
KLFCKHPL_01796 1.5e-25 S CAAX protease self-immunity
KLFCKHPL_01797 2.5e-75 K Helix-turn-helix domain
KLFCKHPL_01798 1.1e-110 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_01801 8.8e-29
KLFCKHPL_01802 1.2e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KLFCKHPL_01803 6.4e-113 S SLAP domain
KLFCKHPL_01804 8.4e-89
KLFCKHPL_01805 3e-09 isdH M Iron Transport-associated domain
KLFCKHPL_01806 6.3e-123 M Iron Transport-associated domain
KLFCKHPL_01807 8.7e-159 isdE P Periplasmic binding protein
KLFCKHPL_01808 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLFCKHPL_01809 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
KLFCKHPL_01810 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLFCKHPL_01811 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KLFCKHPL_01812 1.3e-38 S RelB antitoxin
KLFCKHPL_01813 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
KLFCKHPL_01814 0.0 S membrane
KLFCKHPL_01815 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KLFCKHPL_01816 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLFCKHPL_01817 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KLFCKHPL_01818 3.1e-119 gluP 3.4.21.105 S Rhomboid family
KLFCKHPL_01819 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
KLFCKHPL_01820 1.5e-65 yqhL P Rhodanese-like protein
KLFCKHPL_01821 1e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLFCKHPL_01822 7.8e-222 ynbB 4.4.1.1 P aluminum resistance
KLFCKHPL_01823 2e-263 glnA 6.3.1.2 E glutamine synthetase
KLFCKHPL_01824 1.5e-169
KLFCKHPL_01825 1.7e-147
KLFCKHPL_01826 1.9e-21
KLFCKHPL_01829 2.7e-34
KLFCKHPL_01830 1.2e-128 S interspecies interaction between organisms
KLFCKHPL_01832 7.1e-263 E ABC transporter, substratebinding protein
KLFCKHPL_01833 3.7e-66 K Helix-turn-helix domain, rpiR family
KLFCKHPL_01834 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KLFCKHPL_01835 8.4e-90 nanK GK ROK family
KLFCKHPL_01836 2.3e-56 G Xylose isomerase domain protein TIM barrel
KLFCKHPL_01837 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KLFCKHPL_01838 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLFCKHPL_01839 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KLFCKHPL_01840 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KLFCKHPL_01841 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KLFCKHPL_01842 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KLFCKHPL_01843 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KLFCKHPL_01844 2.1e-255 S Archaea bacterial proteins of unknown function
KLFCKHPL_01845 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KLFCKHPL_01846 1.7e-212 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
KLFCKHPL_01847 1.8e-40 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
KLFCKHPL_01848 1e-24
KLFCKHPL_01849 9.5e-26
KLFCKHPL_01850 2.5e-33
KLFCKHPL_01851 1.4e-53 S Enterocin A Immunity
KLFCKHPL_01852 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KLFCKHPL_01853 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLFCKHPL_01854 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
KLFCKHPL_01855 9.6e-121 K response regulator
KLFCKHPL_01857 0.0 V ABC transporter
KLFCKHPL_01858 4.2e-144 V ABC transporter, ATP-binding protein
KLFCKHPL_01859 1.2e-145 V ABC transporter, ATP-binding protein
KLFCKHPL_01860 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
KLFCKHPL_01861 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KLFCKHPL_01862 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
KLFCKHPL_01863 1.5e-153 spo0J K Belongs to the ParB family
KLFCKHPL_01864 3.4e-138 soj D Sporulation initiation inhibitor
KLFCKHPL_01865 5e-148 noc K Belongs to the ParB family
KLFCKHPL_01866 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KLFCKHPL_01867 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLFCKHPL_01868 3.3e-275 yjeM E Amino Acid
KLFCKHPL_01869 5.8e-83 S Fic/DOC family
KLFCKHPL_01870 9.9e-180
KLFCKHPL_01871 3.1e-93
KLFCKHPL_01872 2.5e-71
KLFCKHPL_01873 2.2e-85 S Protein of unknown function (DUF805)
KLFCKHPL_01874 2.3e-69 O OsmC-like protein
KLFCKHPL_01875 1.4e-207 EGP Major facilitator Superfamily
KLFCKHPL_01876 2.6e-103 sptS 2.7.13.3 T Histidine kinase
KLFCKHPL_01877 1.1e-103 sptS 2.7.13.3 T Histidine kinase
KLFCKHPL_01878 7e-24 K response regulator
KLFCKHPL_01879 2.9e-277 V ABC transporter transmembrane region
KLFCKHPL_01880 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KLFCKHPL_01881 3.1e-130 T Transcriptional regulatory protein, C terminal
KLFCKHPL_01882 5.2e-187 T GHKL domain
KLFCKHPL_01883 3.4e-76 S Peptidase propeptide and YPEB domain
KLFCKHPL_01884 2.5e-72 S Peptidase propeptide and YPEB domain
KLFCKHPL_01885 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KLFCKHPL_01886 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
KLFCKHPL_01887 7e-68 V ABC transporter transmembrane region
KLFCKHPL_01888 5.8e-160 V ABC transporter transmembrane region
KLFCKHPL_01889 4.5e-68 S Domain of unknown function (DUF1934)
KLFCKHPL_01890 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KLFCKHPL_01891 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KLFCKHPL_01892 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLFCKHPL_01893 2.1e-80 K acetyltransferase
KLFCKHPL_01894 1.3e-47 adk 2.7.4.3 F AAA domain
KLFCKHPL_01895 4.4e-285 pipD E Dipeptidase
KLFCKHPL_01896 2.5e-152 msmR K AraC-like ligand binding domain
KLFCKHPL_01897 1.4e-226 pbuX F xanthine permease
KLFCKHPL_01898 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KLFCKHPL_01899 2.4e-43 K Helix-turn-helix
KLFCKHPL_01900 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KLFCKHPL_01902 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KLFCKHPL_01903 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
KLFCKHPL_01905 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
KLFCKHPL_01906 1e-95
KLFCKHPL_01907 9.9e-82 C Flavodoxin
KLFCKHPL_01908 0.0 uvrA3 L excinuclease ABC, A subunit
KLFCKHPL_01909 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KLFCKHPL_01910 2.1e-114 3.6.1.27 I Acid phosphatase homologues
KLFCKHPL_01911 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KLFCKHPL_01912 1.9e-191 yrvN L AAA C-terminal domain
KLFCKHPL_01913 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KLFCKHPL_01914 3.3e-283 treB G phosphotransferase system
KLFCKHPL_01915 1.2e-100 treR K UTRA
KLFCKHPL_01916 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
KLFCKHPL_01917 1.1e-286 clcA P chloride
KLFCKHPL_01918 4e-32 E Zn peptidase
KLFCKHPL_01919 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
KLFCKHPL_01920 1.2e-44
KLFCKHPL_01921 9.1e-106 S Bacteriocin helveticin-J
KLFCKHPL_01922 1.3e-117 S SLAP domain
KLFCKHPL_01923 3.5e-136 S SLAP domain
KLFCKHPL_01924 8e-210
KLFCKHPL_01925 1.2e-18
KLFCKHPL_01926 7.3e-175 EGP Sugar (and other) transporter
KLFCKHPL_01927 1.2e-16
KLFCKHPL_01928 4.4e-138 2.7.13.3 T GHKL domain
KLFCKHPL_01929 1.2e-127 K LytTr DNA-binding domain
KLFCKHPL_01930 6.1e-269 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLFCKHPL_01931 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
KLFCKHPL_01932 9e-144 2.4.2.3 F Phosphorylase superfamily
KLFCKHPL_01933 1.9e-138 2.4.2.3 F Phosphorylase superfamily
KLFCKHPL_01934 1.5e-36 oppA E ABC transporter substrate-binding protein
KLFCKHPL_01936 1.4e-31 O OsmC-like protein
KLFCKHPL_01937 3e-246 brnQ U Component of the transport system for branched-chain amino acids
KLFCKHPL_01938 2.8e-119 3.6.1.55 F NUDIX domain
KLFCKHPL_01939 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLFCKHPL_01940 2.7e-83 S Protein of unknown function (DUF1211)
KLFCKHPL_01941 1.1e-183 scrR K helix_turn _helix lactose operon repressor
KLFCKHPL_01942 3.7e-295 scrB 3.2.1.26 GH32 G invertase
KLFCKHPL_01943 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
KLFCKHPL_01944 2.3e-181 M CHAP domain
KLFCKHPL_01945 3.5e-75
KLFCKHPL_01946 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLFCKHPL_01947 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLFCKHPL_01948 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLFCKHPL_01949 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLFCKHPL_01950 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KLFCKHPL_01951 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KLFCKHPL_01952 9.6e-41 yajC U Preprotein translocase
KLFCKHPL_01953 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLFCKHPL_01954 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLFCKHPL_01955 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KLFCKHPL_01956 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KLFCKHPL_01957 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLFCKHPL_01958 2e-42 yrzL S Belongs to the UPF0297 family
KLFCKHPL_01959 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLFCKHPL_01960 1.1e-50 yrzB S Belongs to the UPF0473 family
KLFCKHPL_01961 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KLFCKHPL_01962 3.5e-54 trxA O Belongs to the thioredoxin family
KLFCKHPL_01963 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KLFCKHPL_01964 1.1e-71 yslB S Protein of unknown function (DUF2507)
KLFCKHPL_01965 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KLFCKHPL_01966 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLFCKHPL_01967 7.7e-30 ropB K Helix-turn-helix domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)