ORF_ID e_value Gene_name EC_number CAZy COGs Description
HPHBAMMA_00004 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HPHBAMMA_00005 4.2e-61 V Abi-like protein
HPHBAMMA_00006 4.9e-282 L AAA domain
HPHBAMMA_00007 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
HPHBAMMA_00008 3.4e-79
HPHBAMMA_00009 1e-242 cpdA S Calcineurin-like phosphoesterase
HPHBAMMA_00010 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HPHBAMMA_00011 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPHBAMMA_00012 1e-107 ypsA S Belongs to the UPF0398 family
HPHBAMMA_00013 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPHBAMMA_00014 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HPHBAMMA_00015 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPHBAMMA_00016 1.3e-114 dnaD L DnaD domain protein
HPHBAMMA_00017 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HPHBAMMA_00018 9.2e-89 ypmB S Protein conserved in bacteria
HPHBAMMA_00019 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HPHBAMMA_00020 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HPHBAMMA_00021 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HPHBAMMA_00022 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HPHBAMMA_00023 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HPHBAMMA_00024 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HPHBAMMA_00025 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPHBAMMA_00026 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HPHBAMMA_00027 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HPHBAMMA_00028 9.7e-169
HPHBAMMA_00029 6.3e-142
HPHBAMMA_00030 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPHBAMMA_00031 1.4e-26
HPHBAMMA_00032 2.1e-143
HPHBAMMA_00033 5.1e-137
HPHBAMMA_00034 4.5e-141
HPHBAMMA_00035 9.6e-124 skfE V ATPases associated with a variety of cellular activities
HPHBAMMA_00036 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
HPHBAMMA_00037 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPHBAMMA_00038 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPHBAMMA_00039 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HPHBAMMA_00040 4.8e-81 mutT 3.6.1.55 F NUDIX domain
HPHBAMMA_00041 1.4e-127 S Peptidase family M23
HPHBAMMA_00042 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPHBAMMA_00043 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPHBAMMA_00044 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HPHBAMMA_00045 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HPHBAMMA_00046 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
HPHBAMMA_00047 6.2e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPHBAMMA_00048 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPHBAMMA_00049 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
HPHBAMMA_00050 3.5e-71 yqeY S YqeY-like protein
HPHBAMMA_00051 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HPHBAMMA_00052 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HPHBAMMA_00053 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
HPHBAMMA_00054 9.1e-54 papP P ABC transporter, permease protein
HPHBAMMA_00055 5.3e-116 P ABC transporter permease
HPHBAMMA_00056 1.5e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPHBAMMA_00057 1e-156 cjaA ET ABC transporter substrate-binding protein
HPHBAMMA_00058 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPHBAMMA_00059 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPHBAMMA_00060 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPHBAMMA_00061 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HPHBAMMA_00062 7.1e-158 metQ1 P Belongs to the nlpA lipoprotein family
HPHBAMMA_00063 1.9e-25
HPHBAMMA_00064 0.0 mco Q Multicopper oxidase
HPHBAMMA_00065 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
HPHBAMMA_00066 0.0 oppA E ABC transporter
HPHBAMMA_00067 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
HPHBAMMA_00068 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
HPHBAMMA_00069 1e-137 S Protein of unknown function (DUF3100)
HPHBAMMA_00070 9.7e-83 S An automated process has identified a potential problem with this gene model
HPHBAMMA_00071 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HPHBAMMA_00072 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPHBAMMA_00073 6.4e-128 K UTRA domain
HPHBAMMA_00074 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPHBAMMA_00075 2e-85 alkD L DNA alkylation repair enzyme
HPHBAMMA_00076 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HPHBAMMA_00077 1.5e-81
HPHBAMMA_00078 3.6e-39 C FMN_bind
HPHBAMMA_00079 8.8e-58 S Peptidase propeptide and YPEB domain
HPHBAMMA_00080 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPHBAMMA_00081 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HPHBAMMA_00082 7.1e-98 E GDSL-like Lipase/Acylhydrolase
HPHBAMMA_00083 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
HPHBAMMA_00084 1.6e-143 aatB ET ABC transporter substrate-binding protein
HPHBAMMA_00085 1e-105 glnQ 3.6.3.21 E ABC transporter
HPHBAMMA_00086 1.5e-107 glnP P ABC transporter permease
HPHBAMMA_00087 0.0 helD 3.6.4.12 L DNA helicase
HPHBAMMA_00088 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HPHBAMMA_00089 1.4e-126 pgm3 G Phosphoglycerate mutase family
HPHBAMMA_00090 8.4e-265 S Fibronectin type III domain
HPHBAMMA_00091 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPHBAMMA_00092 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPHBAMMA_00093 0.0 uup S ABC transporter, ATP-binding protein
HPHBAMMA_00094 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HPHBAMMA_00095 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HPHBAMMA_00096 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HPHBAMMA_00097 7.7e-22
HPHBAMMA_00098 9.3e-64 L PFAM IS66 Orf2 family protein
HPHBAMMA_00099 8.7e-34 S Transposase C of IS166 homeodomain
HPHBAMMA_00100 1.1e-187 L Transposase IS66 family
HPHBAMMA_00101 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPHBAMMA_00102 6.7e-56 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HPHBAMMA_00103 2.2e-15 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HPHBAMMA_00104 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HPHBAMMA_00105 2.2e-85 S ECF transporter, substrate-specific component
HPHBAMMA_00106 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
HPHBAMMA_00107 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPHBAMMA_00108 1.8e-59 yabA L Involved in initiation control of chromosome replication
HPHBAMMA_00109 1.5e-155 holB 2.7.7.7 L DNA polymerase III
HPHBAMMA_00110 8.9e-53 yaaQ S Cyclic-di-AMP receptor
HPHBAMMA_00111 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPHBAMMA_00112 1.1e-34 S Protein of unknown function (DUF2508)
HPHBAMMA_00113 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPHBAMMA_00114 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPHBAMMA_00115 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HPHBAMMA_00116 5.7e-106 2.4.1.58 GT8 M family 8
HPHBAMMA_00117 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPHBAMMA_00118 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPHBAMMA_00119 9e-26
HPHBAMMA_00120 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
HPHBAMMA_00121 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HPHBAMMA_00122 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPHBAMMA_00123 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPHBAMMA_00124 1.5e-11 GT2,GT4 M family 8
HPHBAMMA_00125 2.4e-89 L An automated process has identified a potential problem with this gene model
HPHBAMMA_00126 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
HPHBAMMA_00127 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPHBAMMA_00128 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPHBAMMA_00129 6.5e-154 pstA P Phosphate transport system permease protein PstA
HPHBAMMA_00130 5.8e-211 M Glycosyl hydrolases family 25
HPHBAMMA_00131 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
HPHBAMMA_00132 4.1e-67
HPHBAMMA_00133 5.4e-203 xerS L Belongs to the 'phage' integrase family
HPHBAMMA_00134 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPHBAMMA_00135 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPHBAMMA_00136 1.4e-107 M Transport protein ComB
HPHBAMMA_00137 2.2e-129 blpT
HPHBAMMA_00141 3e-21
HPHBAMMA_00142 3.7e-83
HPHBAMMA_00143 8.2e-31 yozG K Transcriptional regulator
HPHBAMMA_00144 2e-23
HPHBAMMA_00145 1.7e-67
HPHBAMMA_00146 1.1e-164 natA S ABC transporter, ATP-binding protein
HPHBAMMA_00147 1.8e-218 natB CP ABC-2 family transporter protein
HPHBAMMA_00148 1.8e-136 fruR K DeoR C terminal sensor domain
HPHBAMMA_00149 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HPHBAMMA_00150 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HPHBAMMA_00151 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPHBAMMA_00152 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
HPHBAMMA_00153 1.6e-117 fhuC P ABC transporter
HPHBAMMA_00154 5e-129 znuB U ABC 3 transport family
HPHBAMMA_00155 5.9e-264 lctP C L-lactate permease
HPHBAMMA_00156 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPHBAMMA_00157 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
HPHBAMMA_00158 1.2e-11
HPHBAMMA_00159 1.6e-25 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_00161 3.2e-101 3.6.1.27 I Acid phosphatase homologues
HPHBAMMA_00162 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
HPHBAMMA_00163 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPHBAMMA_00164 6.3e-33 S Domain of unknown function (DUF4767)
HPHBAMMA_00165 3.2e-10 S Domain of unknown function DUF87
HPHBAMMA_00166 1.2e-63 S SIR2-like domain
HPHBAMMA_00167 8.3e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HPHBAMMA_00168 2.3e-51 3.1.21.3 V Type I restriction modification DNA specificity domain
HPHBAMMA_00169 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
HPHBAMMA_00170 3.4e-42 S RloB-like protein
HPHBAMMA_00171 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
HPHBAMMA_00172 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HPHBAMMA_00173 0.0 S SLAP domain
HPHBAMMA_00175 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
HPHBAMMA_00176 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HPHBAMMA_00177 1.5e-239 G Bacterial extracellular solute-binding protein
HPHBAMMA_00178 5.7e-18
HPHBAMMA_00179 1.1e-56 S Protein of unknown function (DUF3290)
HPHBAMMA_00180 3e-116 yviA S Protein of unknown function (DUF421)
HPHBAMMA_00181 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HPHBAMMA_00182 8e-182 dnaQ 2.7.7.7 L EXOIII
HPHBAMMA_00183 1.9e-158 endA F DNA RNA non-specific endonuclease
HPHBAMMA_00184 1.3e-281 pipD E Dipeptidase
HPHBAMMA_00185 1.9e-203 malK P ATPases associated with a variety of cellular activities
HPHBAMMA_00186 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
HPHBAMMA_00187 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HPHBAMMA_00188 1e-256 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HPHBAMMA_00189 2.3e-240 G Bacterial extracellular solute-binding protein
HPHBAMMA_00190 1.8e-154 corA P CorA-like Mg2+ transporter protein
HPHBAMMA_00191 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
HPHBAMMA_00192 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
HPHBAMMA_00193 0.0 ydgH S MMPL family
HPHBAMMA_00195 7.8e-26 K Acetyltransferase (GNAT) domain
HPHBAMMA_00196 1.8e-163
HPHBAMMA_00197 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
HPHBAMMA_00198 4.9e-111 ybbL S ABC transporter, ATP-binding protein
HPHBAMMA_00199 0.0 S SH3-like domain
HPHBAMMA_00200 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPHBAMMA_00201 2.1e-171 whiA K May be required for sporulation
HPHBAMMA_00202 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HPHBAMMA_00203 6.2e-165 rapZ S Displays ATPase and GTPase activities
HPHBAMMA_00204 4.1e-90 S Short repeat of unknown function (DUF308)
HPHBAMMA_00205 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPHBAMMA_00206 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPHBAMMA_00207 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HPHBAMMA_00208 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPHBAMMA_00209 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HPHBAMMA_00210 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPHBAMMA_00211 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPHBAMMA_00212 5.1e-17
HPHBAMMA_00213 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPHBAMMA_00214 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPHBAMMA_00215 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPHBAMMA_00216 9.4e-132 comFC S Competence protein
HPHBAMMA_00217 4.7e-246 comFA L Helicase C-terminal domain protein
HPHBAMMA_00218 5.1e-119 yvyE 3.4.13.9 S YigZ family
HPHBAMMA_00219 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
HPHBAMMA_00220 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
HPHBAMMA_00221 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPHBAMMA_00222 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPHBAMMA_00223 5.2e-97 ymfM S Helix-turn-helix domain
HPHBAMMA_00224 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HPHBAMMA_00225 1.9e-236 S Peptidase M16
HPHBAMMA_00226 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HPHBAMMA_00227 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HPHBAMMA_00228 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
HPHBAMMA_00229 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPHBAMMA_00230 2.6e-214 yubA S AI-2E family transporter
HPHBAMMA_00231 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HPHBAMMA_00232 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HPHBAMMA_00233 1.2e-94
HPHBAMMA_00234 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HPHBAMMA_00235 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPHBAMMA_00236 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HPHBAMMA_00237 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HPHBAMMA_00238 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
HPHBAMMA_00239 2e-163 murB 1.3.1.98 M Cell wall formation
HPHBAMMA_00240 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPHBAMMA_00241 1.3e-129 potB P ABC transporter permease
HPHBAMMA_00242 4.8e-127 potC P ABC transporter permease
HPHBAMMA_00243 7.3e-208 potD P ABC transporter
HPHBAMMA_00244 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPHBAMMA_00245 2e-172 ybbR S YbbR-like protein
HPHBAMMA_00246 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPHBAMMA_00247 3.2e-147 S hydrolase
HPHBAMMA_00248 1.8e-75 K Penicillinase repressor
HPHBAMMA_00249 1.6e-118
HPHBAMMA_00250 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPHBAMMA_00251 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPHBAMMA_00252 8.3e-143 licT K CAT RNA binding domain
HPHBAMMA_00253 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HPHBAMMA_00254 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPHBAMMA_00255 1e-149 D Alpha beta
HPHBAMMA_00256 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HPHBAMMA_00257 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HPHBAMMA_00258 8.9e-112 ica2 GT2 M Glycosyl transferase family group 2
HPHBAMMA_00259 8.2e-36
HPHBAMMA_00260 2.2e-90 2.7.7.65 T GGDEF domain
HPHBAMMA_00261 3e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPHBAMMA_00263 2e-310 E Amino acid permease
HPHBAMMA_00264 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HPHBAMMA_00265 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HPHBAMMA_00266 9.7e-52 S Iron-sulfur cluster assembly protein
HPHBAMMA_00267 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HPHBAMMA_00268 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HPHBAMMA_00269 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPHBAMMA_00270 1.7e-34
HPHBAMMA_00271 1.2e-94 sigH K Belongs to the sigma-70 factor family
HPHBAMMA_00272 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPHBAMMA_00273 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPHBAMMA_00274 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPHBAMMA_00275 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPHBAMMA_00276 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPHBAMMA_00277 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HPHBAMMA_00278 4.1e-52
HPHBAMMA_00279 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
HPHBAMMA_00280 8.1e-43
HPHBAMMA_00281 2.4e-183 S AAA domain
HPHBAMMA_00282 1.7e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPHBAMMA_00283 1.4e-23
HPHBAMMA_00284 6.6e-162 czcD P cation diffusion facilitator family transporter
HPHBAMMA_00285 2.2e-125 gpmB G Belongs to the phosphoglycerate mutase family
HPHBAMMA_00286 1.1e-133 S membrane transporter protein
HPHBAMMA_00287 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPHBAMMA_00288 2.6e-106 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HPHBAMMA_00289 4.7e-182 pepA E M42 glutamyl aminopeptidase
HPHBAMMA_00290 2e-310 ybiT S ABC transporter, ATP-binding protein
HPHBAMMA_00291 5.9e-174 S Aldo keto reductase
HPHBAMMA_00292 2.7e-138
HPHBAMMA_00293 2.8e-202 steT E amino acid
HPHBAMMA_00294 2.4e-26 steT E amino acid
HPHBAMMA_00295 8.6e-243 steT E amino acid
HPHBAMMA_00296 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HPHBAMMA_00297 1.9e-147 glnH ET ABC transporter
HPHBAMMA_00298 1.4e-80 K Transcriptional regulator, MarR family
HPHBAMMA_00299 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
HPHBAMMA_00300 0.0 V ABC transporter transmembrane region
HPHBAMMA_00301 1.6e-100 S ABC-type cobalt transport system, permease component
HPHBAMMA_00302 1.8e-246 G MFS/sugar transport protein
HPHBAMMA_00303 1e-44 udk 2.7.1.48 F Zeta toxin
HPHBAMMA_00304 3.8e-46 udk 2.7.1.48 F Zeta toxin
HPHBAMMA_00305 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPHBAMMA_00306 1.2e-146 glnH ET ABC transporter substrate-binding protein
HPHBAMMA_00307 3.7e-90 gluC P ABC transporter permease
HPHBAMMA_00308 4.7e-109 glnP P ABC transporter permease
HPHBAMMA_00309 1.1e-164 S Protein of unknown function (DUF2974)
HPHBAMMA_00310 5.6e-86
HPHBAMMA_00311 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
HPHBAMMA_00312 1.3e-235 G Bacterial extracellular solute-binding protein
HPHBAMMA_00313 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
HPHBAMMA_00314 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPHBAMMA_00315 2.2e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPHBAMMA_00316 0.0 kup P Transport of potassium into the cell
HPHBAMMA_00317 9.1e-175 rihB 3.2.2.1 F Nucleoside
HPHBAMMA_00318 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
HPHBAMMA_00319 1.2e-154 S hydrolase
HPHBAMMA_00320 2.5e-59 S Enterocin A Immunity
HPHBAMMA_00321 3.1e-136 glcR K DeoR C terminal sensor domain
HPHBAMMA_00322 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HPHBAMMA_00323 2e-160 rssA S Phospholipase, patatin family
HPHBAMMA_00324 5.4e-147 S hydrolase
HPHBAMMA_00325 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HPHBAMMA_00326 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
HPHBAMMA_00327 1.6e-80
HPHBAMMA_00328 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPHBAMMA_00329 2.1e-39
HPHBAMMA_00330 1.9e-118 C nitroreductase
HPHBAMMA_00331 1.7e-249 yhdP S Transporter associated domain
HPHBAMMA_00332 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPHBAMMA_00333 0.0 1.3.5.4 C FAD binding domain
HPHBAMMA_00334 2.9e-88 L PFAM transposase, IS4 family protein
HPHBAMMA_00335 2e-49 L PFAM transposase, IS4 family protein
HPHBAMMA_00336 2.4e-212 1.3.5.4 C FAD binding domain
HPHBAMMA_00337 3.4e-126 1.3.5.4 C FAD binding domain
HPHBAMMA_00338 1.6e-15 L hmm pf00665
HPHBAMMA_00339 2.9e-15 M LysM domain protein
HPHBAMMA_00340 3.8e-48 M LysM domain protein
HPHBAMMA_00341 1.4e-86 C Aldo keto reductase
HPHBAMMA_00342 8.3e-181 lacX 5.1.3.3 G Aldose 1-epimerase
HPHBAMMA_00343 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HPHBAMMA_00344 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HPHBAMMA_00345 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
HPHBAMMA_00346 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HPHBAMMA_00347 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPHBAMMA_00348 5.8e-152 dprA LU DNA protecting protein DprA
HPHBAMMA_00349 1.7e-131 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPHBAMMA_00350 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPHBAMMA_00351 1.9e-94 yjcE P Sodium proton antiporter
HPHBAMMA_00352 1.5e-40 yjcE P Sodium proton antiporter
HPHBAMMA_00353 1.1e-66 yjcE P NhaP-type Na H and K H
HPHBAMMA_00354 7.1e-36 yozE S Belongs to the UPF0346 family
HPHBAMMA_00355 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
HPHBAMMA_00356 1.2e-107 hlyIII S protein, hemolysin III
HPHBAMMA_00357 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPHBAMMA_00358 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPHBAMMA_00359 1.6e-85 3.4.21.96 S SLAP domain
HPHBAMMA_00360 8.4e-128 yagE E Amino acid permease
HPHBAMMA_00361 9.7e-65 yagE E amino acid
HPHBAMMA_00362 1.2e-299 I Protein of unknown function (DUF2974)
HPHBAMMA_00363 2.2e-135 pbpX1 V Beta-lactamase
HPHBAMMA_00364 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPHBAMMA_00365 2.7e-216 aspC 2.6.1.1 E Aminotransferase
HPHBAMMA_00366 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPHBAMMA_00367 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPHBAMMA_00368 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HPHBAMMA_00369 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HPHBAMMA_00370 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPHBAMMA_00371 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HPHBAMMA_00372 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPHBAMMA_00373 3.4e-209 yjeM E Amino Acid
HPHBAMMA_00374 7.8e-39 yjeM E Amino Acid
HPHBAMMA_00375 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
HPHBAMMA_00376 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPHBAMMA_00377 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPHBAMMA_00378 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPHBAMMA_00379 1.3e-148
HPHBAMMA_00380 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPHBAMMA_00381 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPHBAMMA_00382 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
HPHBAMMA_00383 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
HPHBAMMA_00384 0.0 comEC S Competence protein ComEC
HPHBAMMA_00385 3.1e-79 comEA L Competence protein ComEA
HPHBAMMA_00386 2.4e-187 ylbL T Belongs to the peptidase S16 family
HPHBAMMA_00387 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPHBAMMA_00388 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HPHBAMMA_00389 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HPHBAMMA_00390 5.9e-211 ftsW D Belongs to the SEDS family
HPHBAMMA_00391 0.0 typA T GTP-binding protein TypA
HPHBAMMA_00392 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPHBAMMA_00393 2.9e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HPHBAMMA_00394 7.1e-46
HPHBAMMA_00395 3.1e-148 glcU U sugar transport
HPHBAMMA_00396 3.7e-250 lctP C L-lactate permease
HPHBAMMA_00397 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPHBAMMA_00398 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPHBAMMA_00399 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPHBAMMA_00400 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HPHBAMMA_00401 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPHBAMMA_00402 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPHBAMMA_00403 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPHBAMMA_00404 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPHBAMMA_00405 1.5e-102 GM NmrA-like family
HPHBAMMA_00406 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPHBAMMA_00407 1.8e-104 3.2.2.20 K acetyltransferase
HPHBAMMA_00409 4.3e-226 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPHBAMMA_00410 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
HPHBAMMA_00411 4.1e-21 K Helix-turn-helix domain, rpiR family
HPHBAMMA_00412 2e-72 K Helix-turn-helix domain, rpiR family
HPHBAMMA_00413 3.3e-106 S domain protein
HPHBAMMA_00414 9.5e-140 V ABC transporter
HPHBAMMA_00415 5.9e-68 S Protein of unknown function (DUF3021)
HPHBAMMA_00416 6e-86
HPHBAMMA_00417 4.4e-172 S Domain of unknown function (DUF389)
HPHBAMMA_00418 1.2e-210 S Bacterial protein of unknown function (DUF871)
HPHBAMMA_00420 2.3e-43 ybhL S Belongs to the BI1 family
HPHBAMMA_00422 3.2e-19
HPHBAMMA_00423 6.2e-87 U TraM recognition site of TraD and TraG
HPHBAMMA_00424 3.9e-32 I mechanosensitive ion channel activity
HPHBAMMA_00426 8.4e-15
HPHBAMMA_00427 1.8e-159 trsE S COG0433 Predicted ATPase
HPHBAMMA_00428 2.1e-32 M Peptidase family M23
HPHBAMMA_00431 2.4e-18 CO COG0526, thiol-disulfide isomerase and thioredoxins
HPHBAMMA_00434 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPHBAMMA_00435 1.2e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HPHBAMMA_00436 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HPHBAMMA_00437 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPHBAMMA_00439 9.8e-139 L An automated process has identified a potential problem with this gene model
HPHBAMMA_00440 2.8e-48 S Peptidase propeptide and YPEB domain
HPHBAMMA_00441 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HPHBAMMA_00442 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPHBAMMA_00443 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPHBAMMA_00444 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPHBAMMA_00447 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HPHBAMMA_00448 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
HPHBAMMA_00449 1.8e-230 steT_1 E amino acid
HPHBAMMA_00450 2.2e-139 puuD S peptidase C26
HPHBAMMA_00452 2.7e-171 V HNH endonuclease
HPHBAMMA_00453 6.4e-135 S PFAM Archaeal ATPase
HPHBAMMA_00454 9.2e-248 yifK E Amino acid permease
HPHBAMMA_00455 9.7e-234 cycA E Amino acid permease
HPHBAMMA_00456 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPHBAMMA_00457 0.0 clpE O AAA domain (Cdc48 subfamily)
HPHBAMMA_00458 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HPHBAMMA_00459 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPHBAMMA_00460 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
HPHBAMMA_00461 0.0 XK27_06780 V ABC transporter permease
HPHBAMMA_00462 1.9e-36
HPHBAMMA_00463 7.9e-291 ytgP S Polysaccharide biosynthesis protein
HPHBAMMA_00464 2.7e-137 lysA2 M Glycosyl hydrolases family 25
HPHBAMMA_00465 2.3e-133 S Protein of unknown function (DUF975)
HPHBAMMA_00466 7.6e-177 pbpX2 V Beta-lactamase
HPHBAMMA_00467 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPHBAMMA_00468 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPHBAMMA_00469 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
HPHBAMMA_00470 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPHBAMMA_00471 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
HPHBAMMA_00472 4.1e-44
HPHBAMMA_00473 1e-207 ywhK S Membrane
HPHBAMMA_00474 1.5e-80 ykuL S (CBS) domain
HPHBAMMA_00475 0.0 cadA P P-type ATPase
HPHBAMMA_00476 2.8e-205 napA P Sodium/hydrogen exchanger family
HPHBAMMA_00477 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HPHBAMMA_00478 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HPHBAMMA_00479 4.1e-276 V ABC transporter transmembrane region
HPHBAMMA_00480 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
HPHBAMMA_00481 5.4e-51
HPHBAMMA_00482 4.2e-154 EGP Major facilitator Superfamily
HPHBAMMA_00483 3e-111 ropB K Transcriptional regulator
HPHBAMMA_00484 2.7e-120 S CAAX protease self-immunity
HPHBAMMA_00485 1.6e-194 S DUF218 domain
HPHBAMMA_00486 0.0 macB_3 V ABC transporter, ATP-binding protein
HPHBAMMA_00487 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HPHBAMMA_00488 8.2e-100 S ECF transporter, substrate-specific component
HPHBAMMA_00489 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
HPHBAMMA_00490 7.3e-175 EGP Sugar (and other) transporter
HPHBAMMA_00491 1.2e-18
HPHBAMMA_00492 8e-210
HPHBAMMA_00493 3.5e-136 S SLAP domain
HPHBAMMA_00494 2.3e-48 S SLAP domain
HPHBAMMA_00495 6.4e-164 D nuclear chromosome segregation
HPHBAMMA_00496 1.2e-105 G Phosphoglycerate mutase family
HPHBAMMA_00497 2.6e-89 G Histidine phosphatase superfamily (branch 1)
HPHBAMMA_00498 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HPHBAMMA_00499 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HPHBAMMA_00501 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HPHBAMMA_00503 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HPHBAMMA_00504 1.8e-184 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HPHBAMMA_00505 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HPHBAMMA_00506 3.7e-143 K SIS domain
HPHBAMMA_00507 4.3e-227 slpX S SLAP domain
HPHBAMMA_00508 1.3e-22 3.6.4.12 S transposase or invertase
HPHBAMMA_00509 6.6e-11
HPHBAMMA_00510 3.2e-240 npr 1.11.1.1 C NADH oxidase
HPHBAMMA_00513 4.4e-239 oppA2 E ABC transporter, substratebinding protein
HPHBAMMA_00514 3.4e-45 oppA2 E ABC transporter, substratebinding protein
HPHBAMMA_00515 3.3e-179
HPHBAMMA_00516 4.6e-123 gntR1 K UTRA
HPHBAMMA_00517 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HPHBAMMA_00518 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HPHBAMMA_00519 1.7e-204 csaB M Glycosyl transferases group 1
HPHBAMMA_00520 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPHBAMMA_00521 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPHBAMMA_00522 1.4e-204 tnpB L Putative transposase DNA-binding domain
HPHBAMMA_00523 0.0 pacL 3.6.3.8 P P-type ATPase
HPHBAMMA_00524 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPHBAMMA_00525 3e-257 epsU S Polysaccharide biosynthesis protein
HPHBAMMA_00526 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HPHBAMMA_00527 4.1e-83 ydcK S Belongs to the SprT family
HPHBAMMA_00529 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HPHBAMMA_00530 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HPHBAMMA_00531 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPHBAMMA_00532 5.8e-203 camS S sex pheromone
HPHBAMMA_00533 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPHBAMMA_00534 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPHBAMMA_00535 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPHBAMMA_00536 2.7e-171 yegS 2.7.1.107 G Lipid kinase
HPHBAMMA_00537 4.3e-108 ybhL S Belongs to the BI1 family
HPHBAMMA_00538 2.6e-57
HPHBAMMA_00539 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
HPHBAMMA_00540 2.8e-244 nhaC C Na H antiporter NhaC
HPHBAMMA_00541 6.3e-201 pbpX V Beta-lactamase
HPHBAMMA_00542 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPHBAMMA_00543 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
HPHBAMMA_00548 1.9e-259 emrY EGP Major facilitator Superfamily
HPHBAMMA_00549 2e-91 yxdD K Bacterial regulatory proteins, tetR family
HPHBAMMA_00550 0.0 4.2.1.53 S Myosin-crossreactive antigen
HPHBAMMA_00551 1.6e-147 S cog cog1373
HPHBAMMA_00552 3.3e-237 L COG2963 Transposase and inactivated derivatives
HPHBAMMA_00553 4.7e-46 pspC KT PspC domain
HPHBAMMA_00555 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPHBAMMA_00556 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPHBAMMA_00557 6.7e-98 M ErfK YbiS YcfS YnhG
HPHBAMMA_00558 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HPHBAMMA_00559 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HPHBAMMA_00560 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPHBAMMA_00561 6.6e-44
HPHBAMMA_00562 1.6e-171 2.7.1.2 GK ROK family
HPHBAMMA_00563 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPHBAMMA_00564 2e-295 S SLAP domain
HPHBAMMA_00565 5.3e-80
HPHBAMMA_00566 0.0 snf 2.7.11.1 KL domain protein
HPHBAMMA_00567 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPHBAMMA_00568 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPHBAMMA_00569 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPHBAMMA_00570 5.6e-183 K Transcriptional regulator
HPHBAMMA_00571 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HPHBAMMA_00572 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPHBAMMA_00573 4e-57 K Helix-turn-helix domain
HPHBAMMA_00574 1.4e-72 V ABC transporter, ATP-binding protein
HPHBAMMA_00575 7.6e-31 S ABC-2 family transporter protein
HPHBAMMA_00576 1.8e-21 S ABC-2 family transporter protein
HPHBAMMA_00577 2.1e-76 S ABC-2 family transporter protein
HPHBAMMA_00578 8.2e-230 pbuG S permease
HPHBAMMA_00579 8.2e-140 cof S haloacid dehalogenase-like hydrolase
HPHBAMMA_00580 9.4e-72
HPHBAMMA_00581 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HPHBAMMA_00582 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HPHBAMMA_00583 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPHBAMMA_00584 1.1e-158 yeaE S Aldo/keto reductase family
HPHBAMMA_00585 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
HPHBAMMA_00586 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
HPHBAMMA_00587 1.3e-282 xylG 3.6.3.17 S ABC transporter
HPHBAMMA_00588 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
HPHBAMMA_00589 8.3e-24 papP P ABC transporter, permease protein
HPHBAMMA_00591 4.5e-58 yodB K Transcriptional regulator, HxlR family
HPHBAMMA_00592 2.2e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPHBAMMA_00593 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HPHBAMMA_00594 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPHBAMMA_00595 6.3e-82 S Aminoacyl-tRNA editing domain
HPHBAMMA_00596 6.1e-224 S SLAP domain
HPHBAMMA_00597 1.5e-97 S CAAX protease self-immunity
HPHBAMMA_00598 1e-12
HPHBAMMA_00599 1.3e-277 arlS 2.7.13.3 T Histidine kinase
HPHBAMMA_00600 1.2e-126 K response regulator
HPHBAMMA_00601 4.7e-97 yceD S Uncharacterized ACR, COG1399
HPHBAMMA_00602 4.6e-216 ylbM S Belongs to the UPF0348 family
HPHBAMMA_00603 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPHBAMMA_00604 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HPHBAMMA_00605 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPHBAMMA_00606 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
HPHBAMMA_00607 4.2e-84 yqeG S HAD phosphatase, family IIIA
HPHBAMMA_00608 4.3e-198 tnpB L Putative transposase DNA-binding domain
HPHBAMMA_00609 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HPHBAMMA_00610 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPHBAMMA_00611 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HPHBAMMA_00612 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPHBAMMA_00613 2.7e-36 yyaR K Acetyltransferase (GNAT) domain
HPHBAMMA_00614 1.6e-96 ybaT E Amino acid permease
HPHBAMMA_00616 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_00617 1.4e-22 S CAAX protease self-immunity
HPHBAMMA_00618 2.4e-17 S CAAX protease self-immunity
HPHBAMMA_00619 4.4e-151 S Metal-independent alpha-mannosidase (GH125)
HPHBAMMA_00620 3.3e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPHBAMMA_00621 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
HPHBAMMA_00622 2.8e-119 3.6.1.55 F NUDIX domain
HPHBAMMA_00623 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
HPHBAMMA_00624 2.7e-83 S Protein of unknown function (DUF1211)
HPHBAMMA_00625 1e-48 S Metal binding domain of Ada
HPHBAMMA_00626 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HPHBAMMA_00627 9e-137 lysR5 K LysR substrate binding domain
HPHBAMMA_00628 8.8e-234 arcA 3.5.3.6 E Arginine
HPHBAMMA_00629 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPHBAMMA_00630 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
HPHBAMMA_00631 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HPHBAMMA_00632 2.3e-215 S Sterol carrier protein domain
HPHBAMMA_00633 1e-20
HPHBAMMA_00634 4.9e-108 K LysR substrate binding domain
HPHBAMMA_00635 9e-98
HPHBAMMA_00636 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HPHBAMMA_00637 6.6e-40
HPHBAMMA_00640 4.9e-118
HPHBAMMA_00641 2.5e-103 pncA Q Isochorismatase family
HPHBAMMA_00643 2e-35
HPHBAMMA_00644 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPHBAMMA_00646 2e-178 MA20_14895 S Conserved hypothetical protein 698
HPHBAMMA_00647 1.1e-83 dps P Belongs to the Dps family
HPHBAMMA_00648 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
HPHBAMMA_00649 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPHBAMMA_00650 1.8e-58 S Putative adhesin
HPHBAMMA_00651 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HPHBAMMA_00652 2e-234 mepA V MATE efflux family protein
HPHBAMMA_00653 5.5e-36
HPHBAMMA_00654 5e-160 scrR K Periplasmic binding protein domain
HPHBAMMA_00655 1.5e-141 msmE G Bacterial extracellular solute-binding protein
HPHBAMMA_00656 5e-85 S PFAM Archaeal ATPase
HPHBAMMA_00657 5.7e-84 S PFAM Archaeal ATPase
HPHBAMMA_00658 7.7e-26
HPHBAMMA_00659 3.1e-71 2.5.1.74 H UbiA prenyltransferase family
HPHBAMMA_00660 1.9e-75 M LysM domain
HPHBAMMA_00661 1.3e-42
HPHBAMMA_00663 4.9e-35
HPHBAMMA_00664 4.5e-76 yniG EGP Major facilitator Superfamily
HPHBAMMA_00665 5.4e-237 L transposase, IS605 OrfB family
HPHBAMMA_00666 1.4e-109 yniG EGP Major facilitator Superfamily
HPHBAMMA_00667 2.4e-128 S cog cog1373
HPHBAMMA_00668 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPHBAMMA_00669 2.1e-13 sprD D Domain of Unknown Function (DUF1542)
HPHBAMMA_00670 1.8e-84 scrR K Periplasmic binding protein domain
HPHBAMMA_00671 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPHBAMMA_00672 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPHBAMMA_00673 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPHBAMMA_00674 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPHBAMMA_00675 2.5e-39 rpmE2 J Ribosomal protein L31
HPHBAMMA_00676 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HPHBAMMA_00677 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HPHBAMMA_00678 9.5e-297 ybeC E amino acid
HPHBAMMA_00679 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPHBAMMA_00680 2.1e-42
HPHBAMMA_00681 1.2e-50
HPHBAMMA_00682 6.8e-184 5.3.3.2 C FMN-dependent dehydrogenase
HPHBAMMA_00683 1.1e-141 yfeO P Voltage gated chloride channel
HPHBAMMA_00684 3.1e-240 oppA E ABC transporter substrate-binding protein
HPHBAMMA_00685 2.1e-308 oppA E ABC transporter substrate-binding protein
HPHBAMMA_00686 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPHBAMMA_00687 0.0 smc D Required for chromosome condensation and partitioning
HPHBAMMA_00688 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPHBAMMA_00689 2.5e-288 pipD E Dipeptidase
HPHBAMMA_00691 3.4e-23
HPHBAMMA_00692 4.1e-133 cysA V ABC transporter, ATP-binding protein
HPHBAMMA_00693 0.0 V FtsX-like permease family
HPHBAMMA_00694 2.7e-258 yfnA E amino acid
HPHBAMMA_00695 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPHBAMMA_00696 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPHBAMMA_00697 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HPHBAMMA_00698 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPHBAMMA_00699 3.6e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HPHBAMMA_00700 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPHBAMMA_00701 4.6e-213 S SLAP domain
HPHBAMMA_00702 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HPHBAMMA_00703 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
HPHBAMMA_00704 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPHBAMMA_00705 3e-38 ynzC S UPF0291 protein
HPHBAMMA_00706 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
HPHBAMMA_00707 0.0 mdlA V ABC transporter
HPHBAMMA_00708 0.0 mdlB V ABC transporter
HPHBAMMA_00709 0.0 pepO 3.4.24.71 O Peptidase family M13
HPHBAMMA_00710 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HPHBAMMA_00711 2.9e-116 plsC 2.3.1.51 I Acyltransferase
HPHBAMMA_00712 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
HPHBAMMA_00713 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HPHBAMMA_00714 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPHBAMMA_00715 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HPHBAMMA_00716 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPHBAMMA_00717 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPHBAMMA_00718 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
HPHBAMMA_00719 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HPHBAMMA_00720 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPHBAMMA_00721 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPHBAMMA_00722 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HPHBAMMA_00723 1.4e-196 nusA K Participates in both transcription termination and antitermination
HPHBAMMA_00724 8.8e-47 ylxR K Protein of unknown function (DUF448)
HPHBAMMA_00725 3.2e-47 rplGA J ribosomal protein
HPHBAMMA_00726 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPHBAMMA_00727 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPHBAMMA_00728 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPHBAMMA_00729 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HPHBAMMA_00730 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPHBAMMA_00731 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPHBAMMA_00732 0.0 dnaK O Heat shock 70 kDa protein
HPHBAMMA_00733 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPHBAMMA_00734 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPHBAMMA_00735 1.5e-102 srtA 3.4.22.70 M sortase family
HPHBAMMA_00736 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HPHBAMMA_00737 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPHBAMMA_00738 7.3e-126 S Alpha/beta hydrolase family
HPHBAMMA_00739 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
HPHBAMMA_00740 4.4e-140 ypuA S Protein of unknown function (DUF1002)
HPHBAMMA_00741 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPHBAMMA_00742 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
HPHBAMMA_00743 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPHBAMMA_00744 9.3e-86
HPHBAMMA_00772 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HPHBAMMA_00773 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
HPHBAMMA_00774 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPHBAMMA_00775 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPHBAMMA_00776 1.7e-29 secG U Preprotein translocase
HPHBAMMA_00777 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPHBAMMA_00778 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPHBAMMA_00779 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HPHBAMMA_00780 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HPHBAMMA_00781 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPHBAMMA_00782 3.4e-161 phnD P Phosphonate ABC transporter
HPHBAMMA_00784 8.8e-84 uspA T universal stress protein
HPHBAMMA_00785 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HPHBAMMA_00786 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPHBAMMA_00787 3e-89 ntd 2.4.2.6 F Nucleoside
HPHBAMMA_00788 5.2e-08
HPHBAMMA_00789 4.5e-68 S Domain of unknown function (DUF1934)
HPHBAMMA_00790 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPHBAMMA_00791 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPHBAMMA_00792 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPHBAMMA_00793 2.1e-80 K acetyltransferase
HPHBAMMA_00794 1.3e-47 adk 2.7.4.3 F AAA domain
HPHBAMMA_00795 4.4e-285 pipD E Dipeptidase
HPHBAMMA_00796 2.5e-152 msmR K AraC-like ligand binding domain
HPHBAMMA_00797 1.4e-226 pbuX F xanthine permease
HPHBAMMA_00798 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPHBAMMA_00799 2.4e-43 K Helix-turn-helix
HPHBAMMA_00800 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HPHBAMMA_00802 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPHBAMMA_00803 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
HPHBAMMA_00804 5e-184 3.2.1.18 GH33 M Rib/alpha-like repeat
HPHBAMMA_00806 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
HPHBAMMA_00807 1e-95
HPHBAMMA_00808 4.2e-63 lmrB EGP Major facilitator Superfamily
HPHBAMMA_00809 2.9e-122 rbtT P Major Facilitator Superfamily
HPHBAMMA_00810 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
HPHBAMMA_00811 2.5e-86 K GNAT family
HPHBAMMA_00812 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HPHBAMMA_00814 4.3e-36
HPHBAMMA_00815 8.2e-288 P ABC transporter
HPHBAMMA_00816 2.4e-51 S Domain of unknown function DUF1829
HPHBAMMA_00817 1.1e-265
HPHBAMMA_00818 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HPHBAMMA_00819 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPHBAMMA_00820 3.9e-25
HPHBAMMA_00821 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HPHBAMMA_00822 5.7e-135 ecsA V ABC transporter, ATP-binding protein
HPHBAMMA_00823 6.5e-221 ecsB U ABC transporter
HPHBAMMA_00824 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPHBAMMA_00826 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HPHBAMMA_00827 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPHBAMMA_00828 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HPHBAMMA_00829 6.9e-218 mepA V MATE efflux family protein
HPHBAMMA_00830 1.8e-176 S SLAP domain
HPHBAMMA_00831 4.4e-283 M Peptidase family M1 domain
HPHBAMMA_00832 2.2e-187 S Bacteriocin helveticin-J
HPHBAMMA_00833 8e-51 L RelB antitoxin
HPHBAMMA_00834 7.4e-105 qmcA O prohibitin homologues
HPHBAMMA_00835 3.5e-25 qmcA O prohibitin homologues
HPHBAMMA_00836 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPHBAMMA_00837 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPHBAMMA_00838 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPHBAMMA_00839 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPHBAMMA_00840 5.1e-251 dnaB L Replication initiation and membrane attachment
HPHBAMMA_00841 2.1e-168 dnaI L Primosomal protein DnaI
HPHBAMMA_00842 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPHBAMMA_00843 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HPHBAMMA_00844 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPHBAMMA_00845 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPHBAMMA_00846 1.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPHBAMMA_00847 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPHBAMMA_00848 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPHBAMMA_00849 9.5e-31
HPHBAMMA_00850 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPHBAMMA_00851 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
HPHBAMMA_00852 2e-157 S reductase
HPHBAMMA_00853 9.3e-35
HPHBAMMA_00854 4.4e-103 K Putative DNA-binding domain
HPHBAMMA_00855 4.1e-36 ptp2 3.1.3.48 T Tyrosine phosphatase family
HPHBAMMA_00856 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
HPHBAMMA_00857 3.8e-105 vanZ V VanZ like family
HPHBAMMA_00858 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HPHBAMMA_00859 3.8e-217 EGP Major facilitator Superfamily
HPHBAMMA_00860 3.9e-195 ampC V Beta-lactamase
HPHBAMMA_00863 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HPHBAMMA_00864 1.3e-113 tdk 2.7.1.21 F thymidine kinase
HPHBAMMA_00865 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPHBAMMA_00866 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPHBAMMA_00867 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPHBAMMA_00868 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPHBAMMA_00869 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HPHBAMMA_00870 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPHBAMMA_00871 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPHBAMMA_00872 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPHBAMMA_00873 2.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPHBAMMA_00874 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPHBAMMA_00875 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPHBAMMA_00876 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HPHBAMMA_00877 2e-30 ywzB S Protein of unknown function (DUF1146)
HPHBAMMA_00878 4.7e-177 mbl D Cell shape determining protein MreB Mrl
HPHBAMMA_00879 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HPHBAMMA_00880 3.3e-33 S Protein of unknown function (DUF2969)
HPHBAMMA_00881 4.7e-216 rodA D Belongs to the SEDS family
HPHBAMMA_00882 1.8e-78 usp6 T universal stress protein
HPHBAMMA_00883 8.4e-39
HPHBAMMA_00884 2.2e-238 rarA L recombination factor protein RarA
HPHBAMMA_00885 1.3e-84 yueI S Protein of unknown function (DUF1694)
HPHBAMMA_00886 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPHBAMMA_00887 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPHBAMMA_00888 7.4e-214 iscS2 2.8.1.7 E Aminotransferase class V
HPHBAMMA_00889 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPHBAMMA_00890 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HPHBAMMA_00891 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPHBAMMA_00892 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPHBAMMA_00893 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
HPHBAMMA_00894 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HPHBAMMA_00895 1.5e-94 S Protein of unknown function (DUF3990)
HPHBAMMA_00896 6.5e-44
HPHBAMMA_00898 0.0 3.6.3.8 P P-type ATPase
HPHBAMMA_00899 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
HPHBAMMA_00900 2.5e-52
HPHBAMMA_00901 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPHBAMMA_00902 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPHBAMMA_00903 5.7e-126 S Haloacid dehalogenase-like hydrolase
HPHBAMMA_00904 2.3e-108 radC L DNA repair protein
HPHBAMMA_00905 2.4e-176 mreB D cell shape determining protein MreB
HPHBAMMA_00906 2e-147 mreC M Involved in formation and maintenance of cell shape
HPHBAMMA_00907 2.7e-94 mreD
HPHBAMMA_00909 6.4e-54 S Protein of unknown function (DUF3397)
HPHBAMMA_00910 6.3e-78 mraZ K Belongs to the MraZ family
HPHBAMMA_00911 2.1e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPHBAMMA_00912 1.8e-54 ftsL D Cell division protein FtsL
HPHBAMMA_00913 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HPHBAMMA_00914 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPHBAMMA_00915 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPHBAMMA_00916 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPHBAMMA_00917 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPHBAMMA_00918 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPHBAMMA_00919 5e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPHBAMMA_00920 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPHBAMMA_00921 1.7e-45 yggT S YGGT family
HPHBAMMA_00922 5.7e-149 ylmH S S4 domain protein
HPHBAMMA_00923 2.8e-74 gpsB D DivIVA domain protein
HPHBAMMA_00924 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPHBAMMA_00925 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
HPHBAMMA_00926 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HPHBAMMA_00927 6.7e-37
HPHBAMMA_00928 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPHBAMMA_00929 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
HPHBAMMA_00930 5.4e-56 XK27_04120 S Putative amino acid metabolism
HPHBAMMA_00931 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPHBAMMA_00932 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPHBAMMA_00933 8.3e-106 S Repeat protein
HPHBAMMA_00934 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPHBAMMA_00935 1.6e-294 L Nuclease-related domain
HPHBAMMA_00936 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HPHBAMMA_00937 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
HPHBAMMA_00938 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPHBAMMA_00939 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPHBAMMA_00940 1.4e-115 mmuP E amino acid
HPHBAMMA_00941 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
HPHBAMMA_00942 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HPHBAMMA_00943 1.7e-284 E Amino acid permease
HPHBAMMA_00944 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HPHBAMMA_00945 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
HPHBAMMA_00946 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HPHBAMMA_00947 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPHBAMMA_00948 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HPHBAMMA_00949 1e-167 cvfB S S1 domain
HPHBAMMA_00950 2.9e-165 xerD D recombinase XerD
HPHBAMMA_00951 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPHBAMMA_00952 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPHBAMMA_00953 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPHBAMMA_00954 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPHBAMMA_00955 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPHBAMMA_00956 2.7e-18 M Lysin motif
HPHBAMMA_00957 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HPHBAMMA_00958 1.4e-24 rpsA 1.17.7.4 J Ribosomal protein S1
HPHBAMMA_00959 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HPHBAMMA_00960 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPHBAMMA_00961 1.4e-75 S Tetratricopeptide repeat protein
HPHBAMMA_00962 3.8e-99 S Tetratricopeptide repeat protein
HPHBAMMA_00963 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPHBAMMA_00964 1.5e-80
HPHBAMMA_00965 1.6e-73 marR K Transcriptional regulator, MarR family
HPHBAMMA_00966 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HPHBAMMA_00967 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPHBAMMA_00968 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPHBAMMA_00969 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPHBAMMA_00970 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HPHBAMMA_00971 2.9e-107 IQ reductase
HPHBAMMA_00972 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPHBAMMA_00973 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPHBAMMA_00974 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HPHBAMMA_00975 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HPHBAMMA_00976 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPHBAMMA_00977 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HPHBAMMA_00978 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HPHBAMMA_00979 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPHBAMMA_00980 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPHBAMMA_00983 3.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HPHBAMMA_00984 1.3e-273 E amino acid
HPHBAMMA_00985 5.2e-26 L Helicase C-terminal domain protein
HPHBAMMA_00986 0.0 L Helicase C-terminal domain protein
HPHBAMMA_00987 4.8e-205 pbpX1 V Beta-lactamase
HPHBAMMA_00988 5.1e-226 N Uncharacterized conserved protein (DUF2075)
HPHBAMMA_00989 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPHBAMMA_00990 1.9e-21
HPHBAMMA_00991 1.7e-147
HPHBAMMA_00992 1.5e-169
HPHBAMMA_00993 2e-263 glnA 6.3.1.2 E glutamine synthetase
HPHBAMMA_00994 3e-221 ynbB 4.4.1.1 P aluminum resistance
HPHBAMMA_00995 1e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPHBAMMA_00996 1.5e-65 yqhL P Rhodanese-like protein
HPHBAMMA_00997 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HPHBAMMA_00998 3.1e-119 gluP 3.4.21.105 S Rhomboid family
HPHBAMMA_00999 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPHBAMMA_01000 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPHBAMMA_01001 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HPHBAMMA_01002 0.0 S membrane
HPHBAMMA_01003 1.4e-52 EGP Sugar (and other) transporter
HPHBAMMA_01004 1e-104
HPHBAMMA_01005 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HPHBAMMA_01006 0.0 copA 3.6.3.54 P P-type ATPase
HPHBAMMA_01007 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPHBAMMA_01008 4.9e-58 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPHBAMMA_01009 2.4e-36
HPHBAMMA_01012 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HPHBAMMA_01013 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPHBAMMA_01014 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPHBAMMA_01015 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
HPHBAMMA_01016 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPHBAMMA_01017 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPHBAMMA_01018 2.8e-157 pstS P Phosphate
HPHBAMMA_01019 2.6e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HPHBAMMA_01020 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HPHBAMMA_01021 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPHBAMMA_01022 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
HPHBAMMA_01023 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPHBAMMA_01024 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPHBAMMA_01025 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPHBAMMA_01026 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPHBAMMA_01027 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPHBAMMA_01028 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPHBAMMA_01029 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HPHBAMMA_01030 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPHBAMMA_01031 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPHBAMMA_01032 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPHBAMMA_01033 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPHBAMMA_01034 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPHBAMMA_01035 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPHBAMMA_01036 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPHBAMMA_01037 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPHBAMMA_01038 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPHBAMMA_01039 2.3e-24 rpmD J Ribosomal protein L30
HPHBAMMA_01040 2.6e-71 rplO J Binds to the 23S rRNA
HPHBAMMA_01041 9e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPHBAMMA_01042 1e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPHBAMMA_01043 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPHBAMMA_01044 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HPHBAMMA_01045 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPHBAMMA_01046 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPHBAMMA_01047 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPHBAMMA_01048 1.4e-60 rplQ J Ribosomal protein L17
HPHBAMMA_01049 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPHBAMMA_01050 3.5e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPHBAMMA_01051 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPHBAMMA_01052 1.5e-149 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPHBAMMA_01053 6.5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPHBAMMA_01054 1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HPHBAMMA_01055 2.7e-155 M Belongs to the glycosyl hydrolase 28 family
HPHBAMMA_01056 1.2e-79 K Acetyltransferase (GNAT) domain
HPHBAMMA_01057 2.4e-10 L Psort location Cytoplasmic, score
HPHBAMMA_01058 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HPHBAMMA_01059 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPHBAMMA_01060 1.3e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HPHBAMMA_01061 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HPHBAMMA_01062 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPHBAMMA_01063 6.3e-120 lsa S ABC transporter
HPHBAMMA_01064 4.2e-92 S SNARE associated Golgi protein
HPHBAMMA_01065 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HPHBAMMA_01066 1.2e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPHBAMMA_01067 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPHBAMMA_01068 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HPHBAMMA_01069 6.8e-110 yjbK S CYTH
HPHBAMMA_01070 4.6e-114 yjbH Q Thioredoxin
HPHBAMMA_01071 4e-13 coiA 3.6.4.12 S Competence protein
HPHBAMMA_01072 3.3e-132 coiA 3.6.4.12 S Competence protein
HPHBAMMA_01073 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPHBAMMA_01074 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPHBAMMA_01075 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPHBAMMA_01076 8.5e-41 ptsH G phosphocarrier protein HPR
HPHBAMMA_01077 5.3e-26
HPHBAMMA_01078 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HPHBAMMA_01079 1.4e-190 I transferase activity, transferring acyl groups other than amino-acyl groups
HPHBAMMA_01080 5.6e-179 S PFAM Archaeal ATPase
HPHBAMMA_01081 3.1e-73 S cog cog1373
HPHBAMMA_01082 1.3e-273 pipD E Dipeptidase
HPHBAMMA_01083 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HPHBAMMA_01084 3.3e-176 hrtB V ABC transporter permease
HPHBAMMA_01085 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
HPHBAMMA_01086 3.5e-111 G phosphoglycerate mutase
HPHBAMMA_01087 2e-140 aroD S Alpha/beta hydrolase family
HPHBAMMA_01088 2.2e-142 S Belongs to the UPF0246 family
HPHBAMMA_01089 1.4e-118 D Alpha beta
HPHBAMMA_01090 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPHBAMMA_01091 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HPHBAMMA_01092 1.6e-85
HPHBAMMA_01093 2.7e-74
HPHBAMMA_01094 1.4e-140 hlyX S Transporter associated domain
HPHBAMMA_01095 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPHBAMMA_01096 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
HPHBAMMA_01097 0.0 clpE O Belongs to the ClpA ClpB family
HPHBAMMA_01098 6.1e-216 3.6.3.6 P Cation transporter/ATPase, N-terminus
HPHBAMMA_01099 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
HPHBAMMA_01100 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
HPHBAMMA_01101 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HPHBAMMA_01102 5e-39 relB L RelB antitoxin
HPHBAMMA_01104 2.2e-97 D VirC1 protein
HPHBAMMA_01105 5e-15 S Domain of Unknown Function with PDB structure (DUF3850)
HPHBAMMA_01107 1e-12
HPHBAMMA_01108 7.6e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPHBAMMA_01109 2.5e-89 M Protein of unknown function (DUF3737)
HPHBAMMA_01110 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
HPHBAMMA_01111 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPHBAMMA_01112 7.7e-67 S SdpI/YhfL protein family
HPHBAMMA_01113 4.4e-129 K Transcriptional regulatory protein, C terminal
HPHBAMMA_01114 1.6e-266 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
HPHBAMMA_01115 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPHBAMMA_01116 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPHBAMMA_01117 1.8e-111 S Protein of unknown function (DUF554)
HPHBAMMA_01118 1.2e-30
HPHBAMMA_01119 1.4e-34
HPHBAMMA_01120 5e-72 rimL J Acetyltransferase (GNAT) domain
HPHBAMMA_01121 8.3e-58
HPHBAMMA_01122 8.9e-292 S ABC transporter
HPHBAMMA_01123 2.4e-136 thrE S Putative threonine/serine exporter
HPHBAMMA_01124 1.1e-83 S Threonine/Serine exporter, ThrE
HPHBAMMA_01125 9.1e-112 yvpB S Peptidase_C39 like family
HPHBAMMA_01126 2.5e-68
HPHBAMMA_01127 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPHBAMMA_01128 5.5e-77 nrdI F NrdI Flavodoxin like
HPHBAMMA_01129 1e-53 tnpB L Putative transposase DNA-binding domain
HPHBAMMA_01130 9.5e-161 tnpB L Putative transposase DNA-binding domain
HPHBAMMA_01131 3.3e-112
HPHBAMMA_01132 2.9e-279 S O-antigen ligase like membrane protein
HPHBAMMA_01133 3.9e-42
HPHBAMMA_01134 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
HPHBAMMA_01135 5e-88 M NlpC/P60 family
HPHBAMMA_01136 1.4e-136 M NlpC P60 family protein
HPHBAMMA_01137 2.6e-118 M NlpC/P60 family
HPHBAMMA_01138 1.6e-41
HPHBAMMA_01139 3.5e-175 S Cysteine-rich secretory protein family
HPHBAMMA_01140 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPHBAMMA_01142 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPHBAMMA_01143 6.5e-146 epsB M biosynthesis protein
HPHBAMMA_01144 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HPHBAMMA_01145 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
HPHBAMMA_01146 6.7e-110 rfbP M Bacterial sugar transferase
HPHBAMMA_01147 1.9e-117 cps1D M Domain of unknown function (DUF4422)
HPHBAMMA_01149 2e-57 clcA P chloride
HPHBAMMA_01150 3.9e-113 L PFAM Integrase catalytic
HPHBAMMA_01151 3.1e-48 S Domain of unknown function (DUF4811)
HPHBAMMA_01152 1.4e-262 lmrB EGP Major facilitator Superfamily
HPHBAMMA_01153 4.2e-77 K MerR HTH family regulatory protein
HPHBAMMA_01154 3.1e-139 S Cysteine-rich secretory protein family
HPHBAMMA_01155 4.6e-274 ycaM E amino acid
HPHBAMMA_01156 2.8e-290
HPHBAMMA_01158 2.6e-189 cggR K Putative sugar-binding domain
HPHBAMMA_01159 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPHBAMMA_01160 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HPHBAMMA_01161 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPHBAMMA_01162 2.2e-179 lysC 2.7.2.4 E Belongs to the aspartokinase family
HPHBAMMA_01163 2.6e-280 thrC 4.2.3.1 E Threonine synthase
HPHBAMMA_01164 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HPHBAMMA_01165 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPHBAMMA_01166 9.4e-118
HPHBAMMA_01167 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPHBAMMA_01169 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPHBAMMA_01170 1.3e-116 S Peptidase family M23
HPHBAMMA_01171 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HPHBAMMA_01172 2.2e-134 glvR K Helix-turn-helix domain, rpiR family
HPHBAMMA_01173 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
HPHBAMMA_01174 5.9e-09
HPHBAMMA_01175 4.4e-43
HPHBAMMA_01176 8.7e-66 2.7.1.191 G PTS system fructose IIA component
HPHBAMMA_01177 0.0 3.6.3.8 P P-type ATPase
HPHBAMMA_01178 4.9e-125
HPHBAMMA_01179 3.5e-241 S response to antibiotic
HPHBAMMA_01180 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HPHBAMMA_01181 1.7e-129 manY G PTS system
HPHBAMMA_01182 1e-173 manN G system, mannose fructose sorbose family IID component
HPHBAMMA_01183 1.1e-62 manO S Domain of unknown function (DUF956)
HPHBAMMA_01184 3.3e-158 K Transcriptional regulator
HPHBAMMA_01185 1.3e-85 maa S transferase hexapeptide repeat
HPHBAMMA_01186 1.3e-241 cycA E Amino acid permease
HPHBAMMA_01187 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPHBAMMA_01188 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPHBAMMA_01189 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPHBAMMA_01190 3.4e-305 mtlR K Mga helix-turn-helix domain
HPHBAMMA_01191 4.7e-61 mtlR K Mga helix-turn-helix domain
HPHBAMMA_01192 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HPHBAMMA_01193 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPHBAMMA_01194 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HPHBAMMA_01195 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
HPHBAMMA_01196 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
HPHBAMMA_01197 2.1e-32
HPHBAMMA_01198 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HPHBAMMA_01199 8.2e-111 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01200 4.1e-26 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01201 3.9e-298 V ABC transporter transmembrane region
HPHBAMMA_01202 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HPHBAMMA_01203 1.7e-193 S TerB-C domain
HPHBAMMA_01204 7.5e-103 G Phosphoglycerate mutase family
HPHBAMMA_01205 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPHBAMMA_01208 6.1e-48 E Pfam:DUF955
HPHBAMMA_01209 1.7e-23 relB L Addiction module antitoxin, RelB DinJ family
HPHBAMMA_01210 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPHBAMMA_01212 3.7e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HPHBAMMA_01214 1.1e-23 S CAAX protease self-immunity
HPHBAMMA_01216 4.1e-34
HPHBAMMA_01217 1e-66 doc S Fic/DOC family
HPHBAMMA_01219 9.4e-51 L An automated process has identified a potential problem with this gene model
HPHBAMMA_01220 7.9e-16 L An automated process has identified a potential problem with this gene model
HPHBAMMA_01222 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
HPHBAMMA_01223 9.7e-205 gatC G PTS system sugar-specific permease component
HPHBAMMA_01224 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HPHBAMMA_01225 3.5e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPHBAMMA_01226 8.3e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HPHBAMMA_01227 2.4e-99 L An automated process has identified a potential problem with this gene model
HPHBAMMA_01228 3.3e-241 V N-6 DNA Methylase
HPHBAMMA_01229 3.8e-82 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HPHBAMMA_01230 1.3e-260 emrY EGP Major facilitator Superfamily
HPHBAMMA_01231 1.1e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPHBAMMA_01232 7.6e-239 pyrP F Permease
HPHBAMMA_01233 1.9e-22 K Putative DNA-binding domain
HPHBAMMA_01234 7e-87 gtcA S Teichoic acid glycosylation protein
HPHBAMMA_01235 4.1e-80 fld C Flavodoxin
HPHBAMMA_01236 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
HPHBAMMA_01237 3.6e-163 yihY S Belongs to the UPF0761 family
HPHBAMMA_01238 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HPHBAMMA_01239 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HPHBAMMA_01240 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HPHBAMMA_01242 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
HPHBAMMA_01245 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPHBAMMA_01246 8.5e-260 qacA EGP Major facilitator Superfamily
HPHBAMMA_01247 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
HPHBAMMA_01248 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPHBAMMA_01249 1.8e-119 S Putative esterase
HPHBAMMA_01250 1.6e-157 2.7.1.208, 2.7.1.211 G phosphotransferase system
HPHBAMMA_01251 4.4e-48 2.7.1.208, 2.7.1.211 G phosphotransferase system
HPHBAMMA_01252 3.4e-195 S Bacterial protein of unknown function (DUF871)
HPHBAMMA_01253 3.7e-130 ybbH_2 K rpiR family
HPHBAMMA_01254 2.2e-31 cydA 1.10.3.14 C ubiquinol oxidase
HPHBAMMA_01255 2.8e-221 cydA 1.10.3.14 C ubiquinol oxidase
HPHBAMMA_01256 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HPHBAMMA_01257 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HPHBAMMA_01258 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPHBAMMA_01259 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPHBAMMA_01260 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPHBAMMA_01261 7.3e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HPHBAMMA_01262 1.1e-231 ndh 1.6.99.3 C NADH dehydrogenase
HPHBAMMA_01263 6.2e-43 1.3.5.4 C FAD binding domain
HPHBAMMA_01264 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPHBAMMA_01265 2.8e-168 K LysR substrate binding domain
HPHBAMMA_01266 1.1e-121 3.6.1.27 I Acid phosphatase homologues
HPHBAMMA_01267 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPHBAMMA_01268 4.7e-275 ytgP S Polysaccharide biosynthesis protein
HPHBAMMA_01269 1.4e-191 oppA E ABC transporter, substratebinding protein
HPHBAMMA_01270 1.3e-30
HPHBAMMA_01271 4.2e-145 pstS P Phosphate
HPHBAMMA_01272 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HPHBAMMA_01273 1.2e-152 pstA P Phosphate transport system permease protein PstA
HPHBAMMA_01274 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPHBAMMA_01275 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
HPHBAMMA_01276 9.5e-121 T Transcriptional regulatory protein, C terminal
HPHBAMMA_01277 1.1e-282 phoR 2.7.13.3 T Histidine kinase
HPHBAMMA_01278 0.0 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HPHBAMMA_01279 1.4e-137 licR 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
HPHBAMMA_01280 5.5e-281 ybgG 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HPHBAMMA_01281 2.7e-149 mngA 2.7.1.195, 2.7.1.202 U system, fructose-specific IIC component
HPHBAMMA_01282 5.3e-37 mngA 2.7.1.195, 2.7.1.202 G Psort location Cytoplasmic, score 9.98
HPHBAMMA_01283 2e-42 fryA 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPHBAMMA_01284 3.7e-93 sip L Belongs to the 'phage' integrase family
HPHBAMMA_01285 6.2e-12
HPHBAMMA_01286 5.6e-08 M Host cell surface-exposed lipoprotein
HPHBAMMA_01287 2.4e-07 S Pfam:DUF955
HPHBAMMA_01288 8.8e-22 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01289 1.4e-17 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01290 4.9e-94 S DNA binding
HPHBAMMA_01296 1.8e-31 S Helix-turn-helix domain
HPHBAMMA_01297 5.5e-18
HPHBAMMA_01299 4.6e-45
HPHBAMMA_01300 1.6e-128 S Protein of unknown function (DUF1351)
HPHBAMMA_01301 5.3e-131 S ERF superfamily
HPHBAMMA_01302 1.2e-100 L Helix-turn-helix domain
HPHBAMMA_01306 1.6e-65 S ORF6C domain
HPHBAMMA_01308 3.7e-37 S VRR_NUC
HPHBAMMA_01310 3.3e-09 arpU S Phage transcriptional regulator, ArpU family
HPHBAMMA_01312 3e-19 ps333 L Terminase small subunit
HPHBAMMA_01313 1.1e-201 S Terminase-like family
HPHBAMMA_01314 6.2e-135 S Protein of unknown function (DUF1073)
HPHBAMMA_01315 1.3e-47 S Phage Mu protein F like protein
HPHBAMMA_01316 5e-12 S Lysin motif
HPHBAMMA_01317 1.6e-57 S Uncharacterized protein conserved in bacteria (DUF2213)
HPHBAMMA_01318 4.1e-34
HPHBAMMA_01319 2.4e-93 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HPHBAMMA_01320 9.2e-20 S Protein of unknown function (DUF4054)
HPHBAMMA_01321 1e-29
HPHBAMMA_01322 1.6e-25
HPHBAMMA_01323 4.3e-31
HPHBAMMA_01324 3.5e-103 Z012_02110 S Protein of unknown function (DUF3383)
HPHBAMMA_01325 9.3e-29
HPHBAMMA_01326 2.9e-09
HPHBAMMA_01328 1e-220 3.4.14.13 M Phage tail tape measure protein TP901
HPHBAMMA_01329 3.8e-59 M LysM domain
HPHBAMMA_01330 2.7e-46
HPHBAMMA_01331 1.1e-102
HPHBAMMA_01332 4.9e-39
HPHBAMMA_01333 6.4e-31
HPHBAMMA_01334 8.8e-114 Z012_12235 S Baseplate J-like protein
HPHBAMMA_01335 2.9e-09
HPHBAMMA_01336 2.3e-34
HPHBAMMA_01341 8.4e-39
HPHBAMMA_01342 1.1e-18 S Phage uncharacterised protein (Phage_XkdX)
HPHBAMMA_01345 4.3e-17
HPHBAMMA_01346 2.9e-29
HPHBAMMA_01347 2e-171 M Glycosyl hydrolases family 25
HPHBAMMA_01348 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
HPHBAMMA_01349 5.6e-95 V ABC-type multidrug transport system, ATPase and permease components
HPHBAMMA_01350 1.3e-157 V ABC-type multidrug transport system, ATPase and permease components
HPHBAMMA_01351 3.3e-37
HPHBAMMA_01352 2.5e-119 K helix_turn_helix, mercury resistance
HPHBAMMA_01353 7.5e-231 pbuG S permease
HPHBAMMA_01354 4.1e-46 U TraM recognition site of TraD and TraG
HPHBAMMA_01358 4.6e-31 M domain protein
HPHBAMMA_01359 7.2e-15 S SLAP domain
HPHBAMMA_01360 1.8e-41 M domain protein
HPHBAMMA_01362 1.4e-24 srtA 3.4.22.70 M sortase family
HPHBAMMA_01364 1.5e-12 S SLAP domain
HPHBAMMA_01369 3.7e-10 S Single-strand binding protein family
HPHBAMMA_01370 2.2e-26 S Type I restriction modification DNA specificity domain
HPHBAMMA_01371 1.1e-188 L N-6 DNA Methylase
HPHBAMMA_01373 1e-33 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01374 7.8e-34 S Phage derived protein Gp49-like (DUF891)
HPHBAMMA_01380 1.5e-26 S Domain of unknown function (DUF771)
HPHBAMMA_01381 4e-21 K Conserved phage C-terminus (Phg_2220_C)
HPHBAMMA_01383 4.1e-09 S Arc-like DNA binding domain
HPHBAMMA_01385 1e-25 K Helix-turn-helix domain
HPHBAMMA_01386 4e-22 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01387 9.8e-16 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01388 1e-08 S Pfam:DUF955
HPHBAMMA_01389 8.5e-151 L Belongs to the 'phage' integrase family
HPHBAMMA_01391 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPHBAMMA_01392 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HPHBAMMA_01393 1.6e-21
HPHBAMMA_01394 3.8e-77 comGF U Putative Competence protein ComGF
HPHBAMMA_01395 2.3e-41
HPHBAMMA_01396 3.1e-43 comGC U competence protein ComGC
HPHBAMMA_01397 1.7e-171 comGB NU type II secretion system
HPHBAMMA_01398 1.7e-179 comGA NU Type II IV secretion system protein
HPHBAMMA_01399 8.9e-133 yebC K Transcriptional regulatory protein
HPHBAMMA_01400 7.6e-94 S VanZ like family
HPHBAMMA_01401 3.5e-101 ylbE GM NAD(P)H-binding
HPHBAMMA_01402 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPHBAMMA_01404 0.0 L Plasmid pRiA4b ORF-3-like protein
HPHBAMMA_01405 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPHBAMMA_01406 1e-23 S Alpha beta hydrolase
HPHBAMMA_01407 1.2e-63 S Alpha beta hydrolase
HPHBAMMA_01408 1.9e-37
HPHBAMMA_01409 7e-50
HPHBAMMA_01410 1.7e-148 S haloacid dehalogenase-like hydrolase
HPHBAMMA_01411 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
HPHBAMMA_01412 8.3e-277 V ABC-type multidrug transport system, ATPase and permease components
HPHBAMMA_01413 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HPHBAMMA_01414 8.5e-178 I Carboxylesterase family
HPHBAMMA_01416 1e-205 M Glycosyl hydrolases family 25
HPHBAMMA_01417 2.8e-157 cinI S Serine hydrolase (FSH1)
HPHBAMMA_01418 4.3e-298 S Predicted membrane protein (DUF2207)
HPHBAMMA_01419 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HPHBAMMA_01421 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
HPHBAMMA_01422 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPHBAMMA_01423 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HPHBAMMA_01424 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HPHBAMMA_01425 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPHBAMMA_01426 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPHBAMMA_01427 3.4e-71 yqhY S Asp23 family, cell envelope-related function
HPHBAMMA_01428 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPHBAMMA_01429 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPHBAMMA_01430 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPHBAMMA_01431 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPHBAMMA_01432 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPHBAMMA_01433 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HPHBAMMA_01434 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
HPHBAMMA_01435 1.1e-77 6.3.3.2 S ASCH
HPHBAMMA_01436 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HPHBAMMA_01437 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPHBAMMA_01438 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPHBAMMA_01439 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPHBAMMA_01440 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPHBAMMA_01441 1.1e-138 stp 3.1.3.16 T phosphatase
HPHBAMMA_01442 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HPHBAMMA_01443 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPHBAMMA_01444 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HPHBAMMA_01445 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HPHBAMMA_01446 1.4e-30
HPHBAMMA_01447 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HPHBAMMA_01448 1.5e-56 asp S Asp23 family, cell envelope-related function
HPHBAMMA_01449 1.7e-304 yloV S DAK2 domain fusion protein YloV
HPHBAMMA_01450 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPHBAMMA_01451 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPHBAMMA_01452 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPHBAMMA_01453 3.1e-192 oppD P Belongs to the ABC transporter superfamily
HPHBAMMA_01454 1.5e-170 oppF P Belongs to the ABC transporter superfamily
HPHBAMMA_01455 2.6e-172 oppB P ABC transporter permease
HPHBAMMA_01456 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
HPHBAMMA_01457 9.7e-46 oppA E ABC transporter substrate-binding protein
HPHBAMMA_01458 4.3e-24 S SLAP domain
HPHBAMMA_01459 7.6e-25 S SLAP domain
HPHBAMMA_01461 9.2e-119 yhiD S MgtC family
HPHBAMMA_01462 7.7e-50 I Protein of unknown function (DUF2974)
HPHBAMMA_01463 7.5e-152 I Protein of unknown function (DUF2974)
HPHBAMMA_01464 1.4e-16
HPHBAMMA_01466 6.7e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HPHBAMMA_01467 4.2e-135 V ABC transporter transmembrane region
HPHBAMMA_01468 3.7e-168 degV S DegV family
HPHBAMMA_01469 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HPHBAMMA_01470 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HPHBAMMA_01471 5.7e-69 rplI J Binds to the 23S rRNA
HPHBAMMA_01472 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HPHBAMMA_01473 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPHBAMMA_01474 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPHBAMMA_01475 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HPHBAMMA_01476 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPHBAMMA_01477 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPHBAMMA_01478 4e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPHBAMMA_01479 2.6e-35 yaaA S S4 domain protein YaaA
HPHBAMMA_01480 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPHBAMMA_01481 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPHBAMMA_01482 0.0 dnaE 2.7.7.7 L DNA polymerase
HPHBAMMA_01483 2.3e-23 S Protein of unknown function (DUF2929)
HPHBAMMA_01484 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HPHBAMMA_01485 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HPHBAMMA_01486 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
HPHBAMMA_01487 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPHBAMMA_01488 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPHBAMMA_01489 2.2e-292 I Acyltransferase
HPHBAMMA_01490 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPHBAMMA_01491 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPHBAMMA_01492 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
HPHBAMMA_01493 1.1e-243 yfnA E Amino Acid
HPHBAMMA_01494 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPHBAMMA_01495 1.3e-148 yxeH S hydrolase
HPHBAMMA_01496 2.7e-32 S reductase
HPHBAMMA_01497 4.4e-39 S reductase
HPHBAMMA_01498 4.8e-34 S reductase
HPHBAMMA_01499 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPHBAMMA_01500 3.7e-60 3.6.1.55 F NUDIX domain
HPHBAMMA_01501 1e-79 S AAA domain
HPHBAMMA_01502 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
HPHBAMMA_01504 5.5e-30
HPHBAMMA_01505 4.3e-40 S Protein of unknown function (DUF2922)
HPHBAMMA_01506 3.1e-131 S SLAP domain
HPHBAMMA_01508 5.3e-41
HPHBAMMA_01509 1.2e-77 K DNA-templated transcription, initiation
HPHBAMMA_01510 1.1e-25
HPHBAMMA_01511 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPHBAMMA_01512 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPHBAMMA_01513 1.4e-104 S SLAP domain
HPHBAMMA_01515 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPHBAMMA_01516 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HPHBAMMA_01517 0.0 yjbQ P TrkA C-terminal domain protein
HPHBAMMA_01518 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPHBAMMA_01519 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
HPHBAMMA_01520 2.1e-130
HPHBAMMA_01521 2.1e-116
HPHBAMMA_01522 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPHBAMMA_01523 1.4e-98 G Aldose 1-epimerase
HPHBAMMA_01524 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPHBAMMA_01525 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPHBAMMA_01526 0.0 XK27_08315 M Sulfatase
HPHBAMMA_01527 3.6e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HPHBAMMA_01528 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
HPHBAMMA_01529 1e-30 S cog cog1373
HPHBAMMA_01530 1.4e-15 S cog cog1373
HPHBAMMA_01531 5.2e-156 hipB K Helix-turn-helix
HPHBAMMA_01532 2.7e-151 I alpha/beta hydrolase fold
HPHBAMMA_01533 1.4e-110 yjbF S SNARE associated Golgi protein
HPHBAMMA_01534 7.5e-100 J Acetyltransferase (GNAT) domain
HPHBAMMA_01535 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPHBAMMA_01536 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
HPHBAMMA_01537 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
HPHBAMMA_01538 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
HPHBAMMA_01539 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
HPHBAMMA_01540 9.6e-138 2.4.2.3 F Phosphorylase superfamily
HPHBAMMA_01541 1.5e-143 2.4.2.3 F Phosphorylase superfamily
HPHBAMMA_01542 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HPHBAMMA_01543 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPHBAMMA_01544 3.2e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HPHBAMMA_01545 4.5e-39 veg S Biofilm formation stimulator VEG
HPHBAMMA_01546 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPHBAMMA_01547 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPHBAMMA_01548 1e-147 tatD L hydrolase, TatD family
HPHBAMMA_01549 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPHBAMMA_01550 1.3e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HPHBAMMA_01551 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HPHBAMMA_01552 2e-103 S TPM domain
HPHBAMMA_01553 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
HPHBAMMA_01554 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPHBAMMA_01555 1.2e-111 E Belongs to the SOS response-associated peptidase family
HPHBAMMA_01557 7.9e-112
HPHBAMMA_01558 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPHBAMMA_01559 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
HPHBAMMA_01560 5.2e-256 pepC 3.4.22.40 E aminopeptidase
HPHBAMMA_01561 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HPHBAMMA_01562 5.1e-198 oppD P Belongs to the ABC transporter superfamily
HPHBAMMA_01563 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPHBAMMA_01564 2.4e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPHBAMMA_01565 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPHBAMMA_01566 3.8e-115 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HPHBAMMA_01567 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HPHBAMMA_01568 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
HPHBAMMA_01569 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
HPHBAMMA_01570 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
HPHBAMMA_01571 5.4e-113
HPHBAMMA_01572 1.7e-139
HPHBAMMA_01573 6.9e-100 V ATPases associated with a variety of cellular activities
HPHBAMMA_01574 3.7e-146 ykuT M mechanosensitive ion channel
HPHBAMMA_01575 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HPHBAMMA_01576 1.3e-36
HPHBAMMA_01577 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPHBAMMA_01578 1.2e-180 ccpA K catabolite control protein A
HPHBAMMA_01579 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HPHBAMMA_01580 4.3e-55
HPHBAMMA_01581 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HPHBAMMA_01582 2.6e-92 yutD S Protein of unknown function (DUF1027)
HPHBAMMA_01583 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPHBAMMA_01584 3.7e-100 S Protein of unknown function (DUF1461)
HPHBAMMA_01585 2.6e-115 dedA S SNARE-like domain protein
HPHBAMMA_01586 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HPHBAMMA_01587 1.3e-51
HPHBAMMA_01588 2.7e-57
HPHBAMMA_01589 1.6e-11
HPHBAMMA_01590 8.1e-126 S PAS domain
HPHBAMMA_01591 2.6e-138 S TerB-C domain
HPHBAMMA_01592 1.4e-245 P P-loop Domain of unknown function (DUF2791)
HPHBAMMA_01593 0.0 lhr L DEAD DEAH box helicase
HPHBAMMA_01594 1.4e-60
HPHBAMMA_01595 4.3e-228 amtB P ammonium transporter
HPHBAMMA_01596 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HPHBAMMA_01598 6.2e-59 psiE S Phosphate-starvation-inducible E
HPHBAMMA_01599 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
HPHBAMMA_01600 2.9e-69 S Iron-sulphur cluster biosynthesis
HPHBAMMA_01602 2.3e-30
HPHBAMMA_01603 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HPHBAMMA_01604 6.2e-12
HPHBAMMA_01605 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPHBAMMA_01606 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPHBAMMA_01607 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPHBAMMA_01608 5.8e-78 M LysM domain protein
HPHBAMMA_01609 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HPHBAMMA_01610 3.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPHBAMMA_01611 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HPHBAMMA_01612 7.2e-56 yheA S Belongs to the UPF0342 family
HPHBAMMA_01613 1e-226 yhaO L Ser Thr phosphatase family protein
HPHBAMMA_01614 0.0 L AAA domain
HPHBAMMA_01615 9.3e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPHBAMMA_01616 7e-22
HPHBAMMA_01617 2.4e-91 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
HPHBAMMA_01618 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPHBAMMA_01619 3.5e-32 ykzG S Belongs to the UPF0356 family
HPHBAMMA_01620 3.5e-70 yebR 1.8.4.14 T GAF domain-containing protein
HPHBAMMA_01622 1.6e-08
HPHBAMMA_01623 1.6e-08
HPHBAMMA_01624 1.6e-08
HPHBAMMA_01625 1.4e-83 K FR47-like protein
HPHBAMMA_01626 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HPHBAMMA_01627 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPHBAMMA_01628 2.2e-165 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPHBAMMA_01629 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPHBAMMA_01630 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPHBAMMA_01631 1.8e-62 yabR J S1 RNA binding domain
HPHBAMMA_01632 6.8e-60 divIC D Septum formation initiator
HPHBAMMA_01633 0.0 L PLD-like domain
HPHBAMMA_01634 4.8e-42 S SnoaL-like domain
HPHBAMMA_01635 5.4e-53 hipB K sequence-specific DNA binding
HPHBAMMA_01636 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HPHBAMMA_01637 3.4e-27
HPHBAMMA_01638 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPHBAMMA_01639 3.5e-70 S Domain of unknown function (DUF3284)
HPHBAMMA_01640 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPHBAMMA_01641 3.7e-131 gmuR K UTRA
HPHBAMMA_01642 8e-225 pbuG S permease
HPHBAMMA_01643 9.7e-146 S haloacid dehalogenase-like hydrolase
HPHBAMMA_01644 2e-225 S cog cog1373
HPHBAMMA_01645 6.1e-61 K Transcriptional regulator
HPHBAMMA_01646 1.3e-94 K Transcriptional regulator
HPHBAMMA_01647 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HPHBAMMA_01648 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPHBAMMA_01649 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
HPHBAMMA_01650 6.5e-64 L RelB antitoxin
HPHBAMMA_01651 2.1e-131 cobQ S glutamine amidotransferase
HPHBAMMA_01652 1.8e-81 M NlpC/P60 family
HPHBAMMA_01655 2.6e-155
HPHBAMMA_01656 7.8e-38
HPHBAMMA_01657 2e-32
HPHBAMMA_01658 3.1e-162 EG EamA-like transporter family
HPHBAMMA_01659 5e-165 EG EamA-like transporter family
HPHBAMMA_01660 1.5e-92 yicL EG EamA-like transporter family
HPHBAMMA_01661 1.1e-114 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HPHBAMMA_01662 6.9e-47 mdtG EGP Major facilitator Superfamily
HPHBAMMA_01663 1.7e-152 mdtG EGP Major facilitator Superfamily
HPHBAMMA_01664 1.3e-174
HPHBAMMA_01665 2.8e-47 lysM M LysM domain
HPHBAMMA_01666 0.0 pepN 3.4.11.2 E aminopeptidase
HPHBAMMA_01667 1.3e-250 dtpT U amino acid peptide transporter
HPHBAMMA_01668 1.2e-18 S Sugar efflux transporter for intercellular exchange
HPHBAMMA_01669 6.6e-70 XK27_02470 K LytTr DNA-binding domain
HPHBAMMA_01670 7.9e-92 liaI S membrane
HPHBAMMA_01671 4e-16
HPHBAMMA_01672 3.9e-186 S Putative peptidoglycan binding domain
HPHBAMMA_01673 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
HPHBAMMA_01674 9e-121
HPHBAMMA_01675 8.4e-25 G Peptidase_C39 like family
HPHBAMMA_01676 2.8e-162 M NlpC/P60 family
HPHBAMMA_01677 6.5e-91 G Peptidase_C39 like family
HPHBAMMA_01678 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HPHBAMMA_01679 2.8e-77 P Cobalt transport protein
HPHBAMMA_01680 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
HPHBAMMA_01681 7.9e-174 K helix_turn_helix, arabinose operon control protein
HPHBAMMA_01682 8.3e-157 htpX O Belongs to the peptidase M48B family
HPHBAMMA_01683 5.1e-96 lemA S LemA family
HPHBAMMA_01684 4.9e-191 ybiR P Citrate transporter
HPHBAMMA_01685 2e-70 S Iron-sulphur cluster biosynthesis
HPHBAMMA_01686 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HPHBAMMA_01687 1.2e-17
HPHBAMMA_01688 1.1e-07 S Uncharacterised protein family (UPF0236)
HPHBAMMA_01689 4.5e-189 ydaM M Glycosyl transferase
HPHBAMMA_01690 6e-28 G Glycosyl hydrolases family 8
HPHBAMMA_01691 6.9e-131 G Glycosyl hydrolases family 8
HPHBAMMA_01692 1e-119 yfbR S HD containing hydrolase-like enzyme
HPHBAMMA_01693 6.4e-159 L HNH nucleases
HPHBAMMA_01694 7.3e-148 S Protein of unknown function (DUF805)
HPHBAMMA_01695 3.4e-135 glnQ E ABC transporter, ATP-binding protein
HPHBAMMA_01696 1.3e-290 glnP P ABC transporter permease
HPHBAMMA_01697 8.9e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HPHBAMMA_01698 1.7e-63 yeaO S Protein of unknown function, DUF488
HPHBAMMA_01699 1.3e-124 terC P Integral membrane protein TerC family
HPHBAMMA_01700 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HPHBAMMA_01701 8.5e-133 cobB K SIR2 family
HPHBAMMA_01702 5.6e-36
HPHBAMMA_01703 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPHBAMMA_01704 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
HPHBAMMA_01705 2.8e-135
HPHBAMMA_01706 1.3e-258 glnPH2 P ABC transporter permease
HPHBAMMA_01707 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPHBAMMA_01708 6.4e-224 S Cysteine-rich secretory protein family
HPHBAMMA_01709 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HPHBAMMA_01710 1.4e-112
HPHBAMMA_01711 2.2e-202 yibE S overlaps another CDS with the same product name
HPHBAMMA_01712 4.9e-129 yibF S overlaps another CDS with the same product name
HPHBAMMA_01713 8.7e-145 I alpha/beta hydrolase fold
HPHBAMMA_01714 0.0 G Belongs to the glycosyl hydrolase 31 family
HPHBAMMA_01715 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPHBAMMA_01716 5.4e-13
HPHBAMMA_01717 6.3e-50 yicL EG EamA-like transporter family
HPHBAMMA_01718 4.3e-107
HPHBAMMA_01719 1.1e-110
HPHBAMMA_01720 5.8e-186 XK27_05540 S DUF218 domain
HPHBAMMA_01721 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
HPHBAMMA_01722 2e-83
HPHBAMMA_01723 1.1e-11
HPHBAMMA_01724 4.7e-25 S Protein conserved in bacteria
HPHBAMMA_01725 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
HPHBAMMA_01726 4.5e-168 L COG3385 FOG Transposase and inactivated derivatives
HPHBAMMA_01727 1.6e-105 tag 3.2.2.20 L glycosylase
HPHBAMMA_01728 3.9e-84
HPHBAMMA_01729 1.3e-270 S Calcineurin-like phosphoesterase
HPHBAMMA_01730 0.0 asnB 6.3.5.4 E Asparagine synthase
HPHBAMMA_01731 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HPHBAMMA_01732 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HPHBAMMA_01733 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPHBAMMA_01734 1.3e-102 S Iron-sulfur cluster assembly protein
HPHBAMMA_01735 1.5e-230 XK27_04775 S PAS domain
HPHBAMMA_01736 1.4e-210 yttB EGP Major facilitator Superfamily
HPHBAMMA_01737 0.0 pepO 3.4.24.71 O Peptidase family M13
HPHBAMMA_01738 0.0 kup P Transport of potassium into the cell
HPHBAMMA_01739 7.3e-74
HPHBAMMA_01740 2.1e-45 S PFAM Archaeal ATPase
HPHBAMMA_01742 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPHBAMMA_01743 5.9e-45
HPHBAMMA_01744 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPHBAMMA_01745 1.6e-161 htrA 3.4.21.107 O serine protease
HPHBAMMA_01746 4.1e-147 vicX 3.1.26.11 S domain protein
HPHBAMMA_01747 3.4e-149 yycI S YycH protein
HPHBAMMA_01748 1.6e-257 yycH S YycH protein
HPHBAMMA_01749 2.2e-305 vicK 2.7.13.3 T Histidine kinase
HPHBAMMA_01750 4.8e-131 K response regulator
HPHBAMMA_01752 4.9e-34
HPHBAMMA_01754 1.3e-147 arbV 2.3.1.51 I Acyl-transferase
HPHBAMMA_01755 5e-156 arbx M Glycosyl transferase family 8
HPHBAMMA_01756 5e-184 arbY M Glycosyl transferase family 8
HPHBAMMA_01757 1.6e-182 arbY M Glycosyl transferase family 8
HPHBAMMA_01758 6e-168 arbZ I Phosphate acyltransferases
HPHBAMMA_01759 1.4e-36 S Cytochrome B5
HPHBAMMA_01760 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
HPHBAMMA_01761 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPHBAMMA_01762 2.3e-187 K Periplasmic binding protein-like domain
HPHBAMMA_01763 2e-106 K Transcriptional regulator, AbiEi antitoxin
HPHBAMMA_01764 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HPHBAMMA_01765 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPHBAMMA_01766 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HPHBAMMA_01767 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HPHBAMMA_01768 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HPHBAMMA_01769 2.1e-164 lacR K Transcriptional regulator
HPHBAMMA_01770 1.1e-137 lacS G Transporter
HPHBAMMA_01771 8.7e-57 lacS G Transporter
HPHBAMMA_01772 2.6e-103 lacS G Transporter
HPHBAMMA_01773 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HPHBAMMA_01774 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPHBAMMA_01775 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HPHBAMMA_01776 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPHBAMMA_01777 4.8e-28
HPHBAMMA_01780 4.3e-67 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01781 3.3e-147 malG P ABC transporter permease
HPHBAMMA_01782 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
HPHBAMMA_01783 1.3e-213 malE G Bacterial extracellular solute-binding protein
HPHBAMMA_01784 6.8e-209 msmX P Belongs to the ABC transporter superfamily
HPHBAMMA_01785 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HPHBAMMA_01786 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HPHBAMMA_01787 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HPHBAMMA_01788 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HPHBAMMA_01789 0.0 fhaB M Rib/alpha-like repeat
HPHBAMMA_01790 5.7e-272 P Sodium:sulfate symporter transmembrane region
HPHBAMMA_01791 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
HPHBAMMA_01792 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
HPHBAMMA_01793 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPHBAMMA_01794 9.5e-261 frdC 1.3.5.4 C FAD binding domain
HPHBAMMA_01795 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HPHBAMMA_01796 3.4e-73 metI P ABC transporter permease
HPHBAMMA_01797 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPHBAMMA_01798 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
HPHBAMMA_01799 2.4e-175 F DNA/RNA non-specific endonuclease
HPHBAMMA_01800 0.0 aha1 P E1-E2 ATPase
HPHBAMMA_01801 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPHBAMMA_01802 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPHBAMMA_01803 1.2e-250 yifK E Amino acid permease
HPHBAMMA_01804 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
HPHBAMMA_01805 1.3e-30
HPHBAMMA_01806 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
HPHBAMMA_01807 3.7e-102 L Integrase
HPHBAMMA_01809 6.3e-54 S COG0790 FOG TPR repeat, SEL1 subfamily
HPHBAMMA_01810 1.7e-39 L Protein of unknown function (DUF3991)
HPHBAMMA_01811 2.1e-111 S Fic/DOC family
HPHBAMMA_01812 8.8e-41 clcA P chloride
HPHBAMMA_01813 1.6e-60 clcA P chloride
HPHBAMMA_01814 4.7e-26 K FCD
HPHBAMMA_01815 3.7e-20
HPHBAMMA_01816 3.2e-139
HPHBAMMA_01817 3.7e-261 V ABC transporter transmembrane region
HPHBAMMA_01818 1.4e-37 S Putative adhesin
HPHBAMMA_01819 7.1e-237 L transposase, IS605 OrfB family
HPHBAMMA_01820 2.1e-28 S Peptidase propeptide and YPEB domain
HPHBAMMA_01821 2.4e-60 ypaA S Protein of unknown function (DUF1304)
HPHBAMMA_01822 2.3e-309 oppA3 E ABC transporter, substratebinding protein
HPHBAMMA_01823 9e-161 V ABC transporter transmembrane region
HPHBAMMA_01824 7e-68 V ABC transporter transmembrane region
HPHBAMMA_01825 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
HPHBAMMA_01826 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HPHBAMMA_01827 2.5e-72 S Peptidase propeptide and YPEB domain
HPHBAMMA_01828 3.4e-76 S Peptidase propeptide and YPEB domain
HPHBAMMA_01829 5.2e-187 T GHKL domain
HPHBAMMA_01830 3.1e-130 T Transcriptional regulatory protein, C terminal
HPHBAMMA_01831 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HPHBAMMA_01832 2.9e-277 V ABC transporter transmembrane region
HPHBAMMA_01833 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
HPHBAMMA_01834 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPHBAMMA_01835 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HPHBAMMA_01836 1.7e-184 G Transmembrane secretion effector
HPHBAMMA_01837 6.1e-136 V ABC transporter transmembrane region
HPHBAMMA_01838 3.5e-222 L transposase, IS605 OrfB family
HPHBAMMA_01839 1.1e-75 V ABC transporter transmembrane region
HPHBAMMA_01840 1.6e-310 oppA E ABC transporter, substratebinding protein
HPHBAMMA_01841 5e-301 oppA E ABC transporter, substratebinding protein
HPHBAMMA_01842 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPHBAMMA_01843 4.6e-257 pepC 3.4.22.40 E aminopeptidase
HPHBAMMA_01845 3.4e-53
HPHBAMMA_01846 3e-53 cvpA S Colicin V production protein
HPHBAMMA_01848 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPHBAMMA_01849 6e-151 3.1.3.48 T Tyrosine phosphatase family
HPHBAMMA_01850 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HPHBAMMA_01851 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HPHBAMMA_01852 1.9e-19
HPHBAMMA_01853 9.9e-39 3.6.3.6 P Cation transporter/ATPase, N-terminus
HPHBAMMA_01854 1.7e-153 ydjP I Alpha/beta hydrolase family
HPHBAMMA_01855 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HPHBAMMA_01856 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
HPHBAMMA_01857 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HPHBAMMA_01858 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HPHBAMMA_01859 9.3e-72 yeaL S Protein of unknown function (DUF441)
HPHBAMMA_01860 3.5e-21
HPHBAMMA_01861 3.6e-146 cbiQ P cobalt transport
HPHBAMMA_01862 0.0 ykoD P ABC transporter, ATP-binding protein
HPHBAMMA_01863 1.5e-95 S UPF0397 protein
HPHBAMMA_01864 2.9e-66 S Domain of unknown function DUF1828
HPHBAMMA_01865 5.5e-09
HPHBAMMA_01866 1.5e-50
HPHBAMMA_01867 2.6e-177 citR K Putative sugar-binding domain
HPHBAMMA_01868 7.2e-248 yjjP S Putative threonine/serine exporter
HPHBAMMA_01870 5.9e-37 M domain protein
HPHBAMMA_01871 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPHBAMMA_01872 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
HPHBAMMA_01873 8.5e-60
HPHBAMMA_01874 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPHBAMMA_01875 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPHBAMMA_01876 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HPHBAMMA_01877 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPHBAMMA_01878 1.2e-222 patA 2.6.1.1 E Aminotransferase
HPHBAMMA_01879 5.7e-62 S SLAP domain
HPHBAMMA_01880 9.1e-106 S Bacteriocin helveticin-J
HPHBAMMA_01881 1.2e-44
HPHBAMMA_01882 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
HPHBAMMA_01883 4e-32 E Zn peptidase
HPHBAMMA_01884 1.9e-286 clcA P chloride
HPHBAMMA_01885 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HPHBAMMA_01886 1.2e-100 treR K UTRA
HPHBAMMA_01887 3.3e-283 treB G phosphotransferase system
HPHBAMMA_01888 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPHBAMMA_01889 1.9e-191 yrvN L AAA C-terminal domain
HPHBAMMA_01890 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPHBAMMA_01891 9e-83 K Acetyltransferase (GNAT) domain
HPHBAMMA_01892 2.9e-229 S Putative peptidoglycan binding domain
HPHBAMMA_01893 8.3e-94 S ECF-type riboflavin transporter, S component
HPHBAMMA_01894 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HPHBAMMA_01895 9.3e-204 pbpX1 V Beta-lactamase
HPHBAMMA_01896 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
HPHBAMMA_01897 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPHBAMMA_01898 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
HPHBAMMA_01899 6.1e-114 3.6.1.27 I Acid phosphatase homologues
HPHBAMMA_01900 2.4e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HPHBAMMA_01901 0.0 uvrA3 L excinuclease ABC, A subunit
HPHBAMMA_01902 9.9e-82 C Flavodoxin
HPHBAMMA_01903 7.4e-40 yabO J S4 domain protein
HPHBAMMA_01904 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPHBAMMA_01905 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPHBAMMA_01906 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPHBAMMA_01907 3.4e-129 S (CBS) domain
HPHBAMMA_01909 2.4e-49 EGP Major facilitator Superfamily
HPHBAMMA_01910 2.4e-45 EGP Major facilitator Superfamily
HPHBAMMA_01911 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
HPHBAMMA_01912 0.0 tetP J elongation factor G
HPHBAMMA_01913 3.5e-160 yvgN C Aldo keto reductase
HPHBAMMA_01914 2e-155 P CorA-like Mg2+ transporter protein
HPHBAMMA_01915 1.6e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPHBAMMA_01916 4.9e-174 ABC-SBP S ABC transporter
HPHBAMMA_01917 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HPHBAMMA_01918 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
HPHBAMMA_01919 5.2e-248 G Major Facilitator
HPHBAMMA_01920 4.1e-18
HPHBAMMA_01921 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HPHBAMMA_01922 1.4e-176 K AI-2E family transporter
HPHBAMMA_01923 8.6e-97 oppA E ABC transporter substrate-binding protein
HPHBAMMA_01924 1.2e-232 oppA E ABC transporter substrate-binding protein
HPHBAMMA_01925 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPHBAMMA_01926 0.0 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPHBAMMA_01927 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPHBAMMA_01929 2.6e-146 S Putative ABC-transporter type IV
HPHBAMMA_01930 1.7e-07 S LPXTG cell wall anchor motif
HPHBAMMA_01931 1.2e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HPHBAMMA_01932 6.4e-113 S SLAP domain
HPHBAMMA_01933 8.4e-89
HPHBAMMA_01934 3e-09 isdH M Iron Transport-associated domain
HPHBAMMA_01935 6.3e-123 M Iron Transport-associated domain
HPHBAMMA_01936 8.7e-159 isdE P Periplasmic binding protein
HPHBAMMA_01937 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPHBAMMA_01938 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
HPHBAMMA_01939 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPHBAMMA_01940 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HPHBAMMA_01941 1.3e-38 S RelB antitoxin
HPHBAMMA_01942 3.4e-75 S cog cog0433
HPHBAMMA_01943 1.9e-110 F DNA/RNA non-specific endonuclease
HPHBAMMA_01944 2.7e-34 S YSIRK type signal peptide
HPHBAMMA_01946 5.5e-53
HPHBAMMA_01947 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HPHBAMMA_01948 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPHBAMMA_01949 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPHBAMMA_01950 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPHBAMMA_01951 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HPHBAMMA_01952 0.0 FbpA K Fibronectin-binding protein
HPHBAMMA_01953 1.1e-66
HPHBAMMA_01954 1.3e-159 degV S EDD domain protein, DegV family
HPHBAMMA_01955 2.6e-61 M Glycosyl hydrolases family 25
HPHBAMMA_01956 1.3e-61 M Glycosyl hydrolases family 25
HPHBAMMA_01957 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
HPHBAMMA_01958 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPHBAMMA_01960 4.5e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HPHBAMMA_01961 7.7e-30 ropB K Helix-turn-helix domain
HPHBAMMA_01962 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPHBAMMA_01963 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HPHBAMMA_01964 1.1e-71 yslB S Protein of unknown function (DUF2507)
HPHBAMMA_01965 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPHBAMMA_01966 3.5e-54 trxA O Belongs to the thioredoxin family
HPHBAMMA_01967 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPHBAMMA_01968 1.1e-50 yrzB S Belongs to the UPF0473 family
HPHBAMMA_01969 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPHBAMMA_01970 2e-42 yrzL S Belongs to the UPF0297 family
HPHBAMMA_01971 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPHBAMMA_01972 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPHBAMMA_01973 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HPHBAMMA_01974 1.7e-215 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPHBAMMA_01975 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPHBAMMA_01976 9.6e-41 yajC U Preprotein translocase
HPHBAMMA_01977 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPHBAMMA_01978 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPHBAMMA_01979 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPHBAMMA_01980 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPHBAMMA_01981 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPHBAMMA_01982 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPHBAMMA_01983 3.5e-75
HPHBAMMA_01984 2.3e-181 M CHAP domain
HPHBAMMA_01985 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HPHBAMMA_01986 3.7e-295 scrB 3.2.1.26 GH32 G invertase
HPHBAMMA_01987 3.3e-183 scrR K helix_turn _helix lactose operon repressor
HPHBAMMA_01988 0.0 pepF E oligoendopeptidase F
HPHBAMMA_01989 2.9e-31
HPHBAMMA_01990 1.3e-69 doc S Prophage maintenance system killer protein
HPHBAMMA_01993 4.6e-27 S Enterocin A Immunity
HPHBAMMA_01994 1.7e-22 blpT
HPHBAMMA_01995 3.4e-100 2.7.6.5 T Region found in RelA / SpoT proteins
HPHBAMMA_01996 1.2e-104 K response regulator
HPHBAMMA_01997 1.1e-103 sptS 2.7.13.3 T Histidine kinase
HPHBAMMA_01998 2.6e-103 sptS 2.7.13.3 T Histidine kinase
HPHBAMMA_01999 7.2e-209 EGP Major facilitator Superfamily
HPHBAMMA_02000 2.3e-69 O OsmC-like protein
HPHBAMMA_02001 2.2e-85 S Protein of unknown function (DUF805)
HPHBAMMA_02002 2.2e-78
HPHBAMMA_02003 3.1e-93
HPHBAMMA_02004 9.9e-180
HPHBAMMA_02005 5.8e-83 S Fic/DOC family
HPHBAMMA_02006 7.4e-275 yjeM E Amino Acid
HPHBAMMA_02007 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPHBAMMA_02008 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HPHBAMMA_02009 5e-148 noc K Belongs to the ParB family
HPHBAMMA_02010 3.4e-138 soj D Sporulation initiation inhibitor
HPHBAMMA_02011 1.5e-153 spo0J K Belongs to the ParB family
HPHBAMMA_02012 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
HPHBAMMA_02013 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPHBAMMA_02014 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
HPHBAMMA_02015 1.2e-145 V ABC transporter, ATP-binding protein
HPHBAMMA_02016 4.2e-144 V ABC transporter, ATP-binding protein
HPHBAMMA_02017 0.0 V ABC transporter
HPHBAMMA_02019 9.6e-121 K response regulator
HPHBAMMA_02020 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HPHBAMMA_02021 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPHBAMMA_02022 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HPHBAMMA_02023 1.4e-53 S Enterocin A Immunity
HPHBAMMA_02024 2.5e-33
HPHBAMMA_02025 9.5e-26
HPHBAMMA_02026 1e-24
HPHBAMMA_02027 1.1e-269 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HPHBAMMA_02028 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HPHBAMMA_02029 2.1e-255 S Archaea bacterial proteins of unknown function
HPHBAMMA_02030 1.2e-16
HPHBAMMA_02031 4.4e-138 2.7.13.3 T GHKL domain
HPHBAMMA_02032 1.2e-127 K LytTr DNA-binding domain
HPHBAMMA_02033 8.9e-268 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)