ORF_ID e_value Gene_name EC_number CAZy COGs Description
APDFHMKJ_00001 7e-87 gtcA S Teichoic acid glycosylation protein
APDFHMKJ_00002 4.1e-80 fld C Flavodoxin
APDFHMKJ_00003 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
APDFHMKJ_00004 3.6e-163 yihY S Belongs to the UPF0761 family
APDFHMKJ_00005 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APDFHMKJ_00006 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
APDFHMKJ_00007 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
APDFHMKJ_00008 3.5e-111 G phosphoglycerate mutase
APDFHMKJ_00009 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
APDFHMKJ_00010 2.1e-175 hrtB V ABC transporter permease
APDFHMKJ_00011 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
APDFHMKJ_00012 1.3e-273 pipD E Dipeptidase
APDFHMKJ_00013 2.4e-44
APDFHMKJ_00014 1.3e-284 lsa S ABC transporter
APDFHMKJ_00015 8.1e-126 S PAS domain
APDFHMKJ_00016 1.6e-11
APDFHMKJ_00017 2.7e-57
APDFHMKJ_00018 6.6e-56
APDFHMKJ_00019 4e-08
APDFHMKJ_00020 5.2e-08
APDFHMKJ_00021 3e-89 ntd 2.4.2.6 F Nucleoside
APDFHMKJ_00022 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APDFHMKJ_00023 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
APDFHMKJ_00024 2.7e-151 I alpha/beta hydrolase fold
APDFHMKJ_00025 2e-129 hipB K Helix-turn-helix
APDFHMKJ_00026 1.4e-15 S cog cog1373
APDFHMKJ_00027 1e-30 S cog cog1373
APDFHMKJ_00028 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
APDFHMKJ_00029 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
APDFHMKJ_00030 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
APDFHMKJ_00031 4.9e-111 ybbL S ABC transporter, ATP-binding protein
APDFHMKJ_00032 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
APDFHMKJ_00033 1.2e-100 treR K UTRA
APDFHMKJ_00034 3.3e-283 treB G phosphotransferase system
APDFHMKJ_00035 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APDFHMKJ_00036 1.9e-191 yrvN L AAA C-terminal domain
APDFHMKJ_00037 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
APDFHMKJ_00038 2.5e-226 pbuG S permease
APDFHMKJ_00039 9.7e-146 S haloacid dehalogenase-like hydrolase
APDFHMKJ_00040 8.7e-139 S cog cog1373
APDFHMKJ_00041 3.1e-48 S Domain of unknown function (DUF4811)
APDFHMKJ_00042 2.4e-262 lmrB EGP Major facilitator Superfamily
APDFHMKJ_00043 4.2e-77 K MerR HTH family regulatory protein
APDFHMKJ_00044 3.1e-139 S Cysteine-rich secretory protein family
APDFHMKJ_00045 4.6e-274 ycaM E amino acid
APDFHMKJ_00046 2.8e-290
APDFHMKJ_00048 2.6e-189 cggR K Putative sugar-binding domain
APDFHMKJ_00049 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APDFHMKJ_00050 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
APDFHMKJ_00051 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APDFHMKJ_00052 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
APDFHMKJ_00053 1.2e-94
APDFHMKJ_00054 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
APDFHMKJ_00055 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APDFHMKJ_00056 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
APDFHMKJ_00057 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
APDFHMKJ_00058 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
APDFHMKJ_00059 2e-163 murB 1.3.1.98 M Cell wall formation
APDFHMKJ_00060 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APDFHMKJ_00061 1.3e-129 potB P ABC transporter permease
APDFHMKJ_00062 4.8e-127 potC P ABC transporter permease
APDFHMKJ_00063 7.3e-208 potD P ABC transporter
APDFHMKJ_00064 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APDFHMKJ_00065 2e-172 ybbR S YbbR-like protein
APDFHMKJ_00066 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APDFHMKJ_00067 1.4e-147 S hydrolase
APDFHMKJ_00068 1.8e-75 K Penicillinase repressor
APDFHMKJ_00069 1.6e-118
APDFHMKJ_00070 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APDFHMKJ_00071 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
APDFHMKJ_00072 7e-142 licT K CAT RNA binding domain
APDFHMKJ_00073 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
APDFHMKJ_00074 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APDFHMKJ_00075 1e-149 D Alpha beta
APDFHMKJ_00076 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
APDFHMKJ_00077 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
APDFHMKJ_00078 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
APDFHMKJ_00079 8.2e-36
APDFHMKJ_00080 2.2e-90 2.7.7.65 T GGDEF domain
APDFHMKJ_00081 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APDFHMKJ_00083 2e-310 E Amino acid permease
APDFHMKJ_00084 5.8e-100 L Helix-turn-helix domain
APDFHMKJ_00085 1.3e-160 L hmm pf00665
APDFHMKJ_00087 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APDFHMKJ_00088 3.5e-101 ylbE GM NAD(P)H-binding
APDFHMKJ_00089 7.6e-94 S VanZ like family
APDFHMKJ_00090 8.9e-133 yebC K Transcriptional regulatory protein
APDFHMKJ_00091 1.7e-179 comGA NU Type II IV secretion system protein
APDFHMKJ_00092 1.7e-171 comGB NU type II secretion system
APDFHMKJ_00093 3.1e-43 comGC U competence protein ComGC
APDFHMKJ_00094 1.8e-69
APDFHMKJ_00095 2.3e-41
APDFHMKJ_00096 3.8e-77 comGF U Putative Competence protein ComGF
APDFHMKJ_00097 1.6e-21
APDFHMKJ_00098 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
APDFHMKJ_00099 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APDFHMKJ_00101 2.5e-89 M Protein of unknown function (DUF3737)
APDFHMKJ_00102 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
APDFHMKJ_00103 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
APDFHMKJ_00104 7.7e-67 S SdpI/YhfL protein family
APDFHMKJ_00105 2.6e-60 K Transcriptional regulatory protein, C terminal
APDFHMKJ_00106 1e-47 K Transcriptional regulatory protein, C terminal
APDFHMKJ_00107 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
APDFHMKJ_00108 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APDFHMKJ_00109 3.8e-105 vanZ V VanZ like family
APDFHMKJ_00110 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
APDFHMKJ_00111 3.8e-217 EGP Major facilitator Superfamily
APDFHMKJ_00112 3.9e-195 ampC V Beta-lactamase
APDFHMKJ_00115 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
APDFHMKJ_00116 1.3e-113 tdk 2.7.1.21 F thymidine kinase
APDFHMKJ_00117 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APDFHMKJ_00118 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APDFHMKJ_00119 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APDFHMKJ_00120 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APDFHMKJ_00121 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
APDFHMKJ_00122 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APDFHMKJ_00123 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APDFHMKJ_00124 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APDFHMKJ_00125 2.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APDFHMKJ_00126 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APDFHMKJ_00127 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APDFHMKJ_00128 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
APDFHMKJ_00129 9e-20 ywzB S Protein of unknown function (DUF1146)
APDFHMKJ_00130 7.7e-30 ropB K Helix-turn-helix domain
APDFHMKJ_00131 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APDFHMKJ_00132 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APDFHMKJ_00133 1.1e-71 yslB S Protein of unknown function (DUF2507)
APDFHMKJ_00134 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APDFHMKJ_00135 3.5e-54 trxA O Belongs to the thioredoxin family
APDFHMKJ_00136 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APDFHMKJ_00137 1.1e-50 yrzB S Belongs to the UPF0473 family
APDFHMKJ_00138 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APDFHMKJ_00139 2e-42 yrzL S Belongs to the UPF0297 family
APDFHMKJ_00140 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APDFHMKJ_00141 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APDFHMKJ_00142 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
APDFHMKJ_00143 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APDFHMKJ_00144 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APDFHMKJ_00145 9.6e-41 yajC U Preprotein translocase
APDFHMKJ_00146 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APDFHMKJ_00147 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APDFHMKJ_00148 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APDFHMKJ_00149 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APDFHMKJ_00150 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APDFHMKJ_00151 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APDFHMKJ_00152 3.5e-75
APDFHMKJ_00153 2.3e-181 M CHAP domain
APDFHMKJ_00154 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
APDFHMKJ_00155 3.7e-295 scrB 3.2.1.26 GH32 G invertase
APDFHMKJ_00156 1.1e-183 scrR K helix_turn _helix lactose operon repressor
APDFHMKJ_00157 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
APDFHMKJ_00158 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
APDFHMKJ_00159 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
APDFHMKJ_00160 1.7e-284 E Amino acid permease
APDFHMKJ_00161 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
APDFHMKJ_00162 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
APDFHMKJ_00163 1.4e-115 mmuP E amino acid
APDFHMKJ_00164 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
APDFHMKJ_00165 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APDFHMKJ_00166 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APDFHMKJ_00167 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
APDFHMKJ_00168 4.7e-182 pepA E M42 glutamyl aminopeptidase
APDFHMKJ_00169 2.2e-311 ybiT S ABC transporter, ATP-binding protein
APDFHMKJ_00170 5.9e-174 S Aldo keto reductase
APDFHMKJ_00171 2.7e-138
APDFHMKJ_00172 2.8e-202 steT E amino acid
APDFHMKJ_00173 2.4e-26 steT E amino acid
APDFHMKJ_00174 8.6e-243 steT E amino acid
APDFHMKJ_00175 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
APDFHMKJ_00176 1.9e-147 glnH ET ABC transporter
APDFHMKJ_00177 1.4e-80 K Transcriptional regulator, MarR family
APDFHMKJ_00178 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
APDFHMKJ_00179 0.0 V ABC transporter transmembrane region
APDFHMKJ_00180 1.6e-100 S ABC-type cobalt transport system, permease component
APDFHMKJ_00181 1e-246 G MFS/sugar transport protein
APDFHMKJ_00182 1e-44 udk 2.7.1.48 F Zeta toxin
APDFHMKJ_00183 3.8e-46 udk 2.7.1.48 F Zeta toxin
APDFHMKJ_00184 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APDFHMKJ_00185 1.2e-146 glnH ET ABC transporter substrate-binding protein
APDFHMKJ_00186 3.7e-90 gluC P ABC transporter permease
APDFHMKJ_00187 4.7e-109 glnP P ABC transporter permease
APDFHMKJ_00188 1.1e-164 S Protein of unknown function (DUF2974)
APDFHMKJ_00189 5.6e-86
APDFHMKJ_00190 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
APDFHMKJ_00191 1.3e-235 G Bacterial extracellular solute-binding protein
APDFHMKJ_00192 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
APDFHMKJ_00193 1e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APDFHMKJ_00194 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APDFHMKJ_00195 0.0 kup P Transport of potassium into the cell
APDFHMKJ_00196 9.1e-175 rihB 3.2.2.1 F Nucleoside
APDFHMKJ_00197 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
APDFHMKJ_00198 1.2e-154 S hydrolase
APDFHMKJ_00199 2.5e-59 S Enterocin A Immunity
APDFHMKJ_00200 3.1e-136 glcR K DeoR C terminal sensor domain
APDFHMKJ_00201 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
APDFHMKJ_00202 2e-160 rssA S Phospholipase, patatin family
APDFHMKJ_00203 5.4e-147 S hydrolase
APDFHMKJ_00204 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
APDFHMKJ_00205 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
APDFHMKJ_00206 1.6e-80
APDFHMKJ_00207 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
APDFHMKJ_00208 2.1e-39
APDFHMKJ_00209 3.9e-119 C nitroreductase
APDFHMKJ_00210 1.7e-249 yhdP S Transporter associated domain
APDFHMKJ_00211 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APDFHMKJ_00212 0.0 1.3.5.4 C FAD binding domain
APDFHMKJ_00213 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
APDFHMKJ_00214 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
APDFHMKJ_00215 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
APDFHMKJ_00216 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
APDFHMKJ_00217 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
APDFHMKJ_00218 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APDFHMKJ_00219 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APDFHMKJ_00220 2.3e-56 G Xylose isomerase domain protein TIM barrel
APDFHMKJ_00221 8.4e-90 nanK GK ROK family
APDFHMKJ_00222 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
APDFHMKJ_00223 3.7e-66 K Helix-turn-helix domain, rpiR family
APDFHMKJ_00224 7.1e-263 E ABC transporter, substratebinding protein
APDFHMKJ_00225 9.1e-10 K peptidyl-tyrosine sulfation
APDFHMKJ_00227 1.2e-128 S interspecies interaction between organisms
APDFHMKJ_00228 2.7e-34
APDFHMKJ_00231 1.9e-21
APDFHMKJ_00232 1.7e-147
APDFHMKJ_00233 1.5e-169
APDFHMKJ_00234 2e-263 glnA 6.3.1.2 E glutamine synthetase
APDFHMKJ_00235 7.8e-222 ynbB 4.4.1.1 P aluminum resistance
APDFHMKJ_00236 1e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APDFHMKJ_00237 1.5e-65 yqhL P Rhodanese-like protein
APDFHMKJ_00238 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
APDFHMKJ_00239 3.1e-119 gluP 3.4.21.105 S Rhomboid family
APDFHMKJ_00240 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APDFHMKJ_00241 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APDFHMKJ_00242 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
APDFHMKJ_00243 0.0 S membrane
APDFHMKJ_00244 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
APDFHMKJ_00245 1.3e-38 S RelB antitoxin
APDFHMKJ_00246 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
APDFHMKJ_00247 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APDFHMKJ_00248 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
APDFHMKJ_00249 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APDFHMKJ_00250 8.7e-159 isdE P Periplasmic binding protein
APDFHMKJ_00251 6.3e-123 M Iron Transport-associated domain
APDFHMKJ_00252 3e-09 isdH M Iron Transport-associated domain
APDFHMKJ_00253 8.4e-89
APDFHMKJ_00254 6.4e-113 S SLAP domain
APDFHMKJ_00255 1.2e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
APDFHMKJ_00257 1.6e-25 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_00258 1.2e-11
APDFHMKJ_00259 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
APDFHMKJ_00260 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APDFHMKJ_00261 4.5e-264 lctP C L-lactate permease
APDFHMKJ_00262 5e-129 znuB U ABC 3 transport family
APDFHMKJ_00263 1.6e-117 fhuC P ABC transporter
APDFHMKJ_00264 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
APDFHMKJ_00265 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
APDFHMKJ_00266 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
APDFHMKJ_00267 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
APDFHMKJ_00268 1.8e-136 fruR K DeoR C terminal sensor domain
APDFHMKJ_00269 1.8e-218 natB CP ABC-2 family transporter protein
APDFHMKJ_00270 1.1e-164 natA S ABC transporter, ATP-binding protein
APDFHMKJ_00271 1.7e-67
APDFHMKJ_00272 2e-23
APDFHMKJ_00273 8.2e-31 yozG K Transcriptional regulator
APDFHMKJ_00274 3.7e-83
APDFHMKJ_00275 3e-21
APDFHMKJ_00278 2.2e-22
APDFHMKJ_00279 3.3e-140 repB EP Plasmid replication protein
APDFHMKJ_00280 2.2e-78 S helix_turn_helix, Deoxyribose operon repressor
APDFHMKJ_00281 8.1e-175 ulaG S Beta-lactamase superfamily domain
APDFHMKJ_00282 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APDFHMKJ_00283 5.3e-233 ulaA S PTS system sugar-specific permease component
APDFHMKJ_00284 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
APDFHMKJ_00285 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
APDFHMKJ_00286 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
APDFHMKJ_00287 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
APDFHMKJ_00288 5.2e-68 L haloacid dehalogenase-like hydrolase
APDFHMKJ_00289 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
APDFHMKJ_00290 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
APDFHMKJ_00291 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
APDFHMKJ_00292 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
APDFHMKJ_00293 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APDFHMKJ_00294 7.5e-100 J Acetyltransferase (GNAT) domain
APDFHMKJ_00295 1.4e-110 yjbF S SNARE associated Golgi protein
APDFHMKJ_00296 2.6e-61 M Glycosyl hydrolases family 25
APDFHMKJ_00297 1.3e-61 M Glycosyl hydrolases family 25
APDFHMKJ_00298 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
APDFHMKJ_00299 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APDFHMKJ_00301 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APDFHMKJ_00302 7.5e-103 G Phosphoglycerate mutase family
APDFHMKJ_00303 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
APDFHMKJ_00305 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APDFHMKJ_00306 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APDFHMKJ_00307 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APDFHMKJ_00308 0.0 snf 2.7.11.1 KL domain protein
APDFHMKJ_00309 2e-35
APDFHMKJ_00311 3.8e-104 pncA Q Isochorismatase family
APDFHMKJ_00312 4.9e-118
APDFHMKJ_00315 3.6e-63
APDFHMKJ_00316 1.4e-34
APDFHMKJ_00317 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APDFHMKJ_00318 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
APDFHMKJ_00319 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
APDFHMKJ_00320 2.3e-198 oppD P Belongs to the ABC transporter superfamily
APDFHMKJ_00321 1.9e-175 oppF P Belongs to the ABC transporter superfamily
APDFHMKJ_00322 5.2e-256 pepC 3.4.22.40 E aminopeptidase
APDFHMKJ_00323 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
APDFHMKJ_00324 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APDFHMKJ_00325 7.9e-112
APDFHMKJ_00327 1.2e-111 E Belongs to the SOS response-associated peptidase family
APDFHMKJ_00328 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
APDFHMKJ_00329 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
APDFHMKJ_00330 2e-103 S TPM domain
APDFHMKJ_00331 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
APDFHMKJ_00332 1e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
APDFHMKJ_00333 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APDFHMKJ_00334 1e-147 tatD L hydrolase, TatD family
APDFHMKJ_00335 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APDFHMKJ_00336 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APDFHMKJ_00337 4.5e-39 veg S Biofilm formation stimulator VEG
APDFHMKJ_00338 1.1e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
APDFHMKJ_00339 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APDFHMKJ_00340 5.8e-211 M Glycosyl hydrolases family 25
APDFHMKJ_00341 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
APDFHMKJ_00342 4.1e-67
APDFHMKJ_00343 5.4e-203 xerS L Belongs to the 'phage' integrase family
APDFHMKJ_00344 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APDFHMKJ_00345 9.4e-132 comFC S Competence protein
APDFHMKJ_00346 4.7e-246 comFA L Helicase C-terminal domain protein
APDFHMKJ_00347 2.5e-118 yvyE 3.4.13.9 S YigZ family
APDFHMKJ_00348 1.9e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
APDFHMKJ_00349 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
APDFHMKJ_00350 8.5e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APDFHMKJ_00351 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APDFHMKJ_00352 5.2e-97 ymfM S Helix-turn-helix domain
APDFHMKJ_00353 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
APDFHMKJ_00354 1.9e-236 S Peptidase M16
APDFHMKJ_00355 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
APDFHMKJ_00356 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
APDFHMKJ_00357 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
APDFHMKJ_00358 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APDFHMKJ_00359 2.6e-214 yubA S AI-2E family transporter
APDFHMKJ_00360 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
APDFHMKJ_00361 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
APDFHMKJ_00362 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
APDFHMKJ_00363 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APDFHMKJ_00364 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APDFHMKJ_00365 7.2e-56 yheA S Belongs to the UPF0342 family
APDFHMKJ_00366 1e-226 yhaO L Ser Thr phosphatase family protein
APDFHMKJ_00367 0.0 L AAA domain
APDFHMKJ_00368 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
APDFHMKJ_00369 2.9e-23
APDFHMKJ_00371 1e-48 S Metal binding domain of Ada
APDFHMKJ_00372 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
APDFHMKJ_00373 9e-137 lysR5 K LysR substrate binding domain
APDFHMKJ_00374 8.8e-234 arcA 3.5.3.6 E Arginine
APDFHMKJ_00375 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APDFHMKJ_00376 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
APDFHMKJ_00377 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
APDFHMKJ_00378 2.3e-215 S Sterol carrier protein domain
APDFHMKJ_00379 1e-20
APDFHMKJ_00380 4.9e-108 K LysR substrate binding domain
APDFHMKJ_00381 9e-98
APDFHMKJ_00382 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
APDFHMKJ_00383 1.3e-31
APDFHMKJ_00384 3.9e-131 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_00386 9.2e-119 yhiD S MgtC family
APDFHMKJ_00387 4.7e-227 I Protein of unknown function (DUF2974)
APDFHMKJ_00388 1.4e-16
APDFHMKJ_00390 3.3e-166 scrK 2.7.1.2, 2.7.1.4 GK ROK family
APDFHMKJ_00391 4.2e-135 V ABC transporter transmembrane region
APDFHMKJ_00392 3.7e-168 degV S DegV family
APDFHMKJ_00393 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
APDFHMKJ_00394 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
APDFHMKJ_00395 5.7e-69 rplI J Binds to the 23S rRNA
APDFHMKJ_00396 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
APDFHMKJ_00397 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APDFHMKJ_00398 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APDFHMKJ_00399 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
APDFHMKJ_00400 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APDFHMKJ_00401 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APDFHMKJ_00402 4e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APDFHMKJ_00403 2.6e-35 yaaA S S4 domain protein YaaA
APDFHMKJ_00404 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APDFHMKJ_00405 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APDFHMKJ_00406 2.3e-168 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
APDFHMKJ_00407 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APDFHMKJ_00408 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
APDFHMKJ_00409 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
APDFHMKJ_00410 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
APDFHMKJ_00411 2.1e-32
APDFHMKJ_00412 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
APDFHMKJ_00413 2.3e-156 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_00414 3.9e-298 V ABC transporter transmembrane region
APDFHMKJ_00415 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
APDFHMKJ_00416 1.7e-193 S TerB-C domain
APDFHMKJ_00417 4.7e-26 K FCD
APDFHMKJ_00418 1.6e-60 clcA P chloride
APDFHMKJ_00419 8.8e-41 clcA P chloride
APDFHMKJ_00420 4.2e-101 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
APDFHMKJ_00421 2.5e-86 K GNAT family
APDFHMKJ_00422 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
APDFHMKJ_00423 4.7e-36 rbtT P Major Facilitator Superfamily
APDFHMKJ_00424 7e-24 K response regulator
APDFHMKJ_00425 1.1e-103 sptS 2.7.13.3 T Histidine kinase
APDFHMKJ_00426 2.6e-103 sptS 2.7.13.3 T Histidine kinase
APDFHMKJ_00427 1.4e-207 EGP Major facilitator Superfamily
APDFHMKJ_00428 2.3e-69 O OsmC-like protein
APDFHMKJ_00429 2.2e-85 S Protein of unknown function (DUF805)
APDFHMKJ_00430 2.5e-71
APDFHMKJ_00431 3.1e-93
APDFHMKJ_00432 9.9e-180
APDFHMKJ_00433 5.8e-83 S Fic/DOC family
APDFHMKJ_00434 3.3e-275 yjeM E Amino Acid
APDFHMKJ_00435 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APDFHMKJ_00436 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
APDFHMKJ_00437 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
APDFHMKJ_00438 2.5e-264 3.6.3.6 P Cation transporter/ATPase, N-terminus
APDFHMKJ_00439 1.9e-19
APDFHMKJ_00440 3.4e-129 S (CBS) domain
APDFHMKJ_00441 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APDFHMKJ_00442 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APDFHMKJ_00443 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APDFHMKJ_00444 7.4e-40 yabO J S4 domain protein
APDFHMKJ_00445 3.7e-102 L Integrase
APDFHMKJ_00446 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
APDFHMKJ_00447 1.3e-30
APDFHMKJ_00448 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
APDFHMKJ_00449 1.2e-250 yifK E Amino acid permease
APDFHMKJ_00450 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APDFHMKJ_00451 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APDFHMKJ_00452 0.0 aha1 P E1-E2 ATPase
APDFHMKJ_00453 2.4e-175 F DNA/RNA non-specific endonuclease
APDFHMKJ_00454 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
APDFHMKJ_00455 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APDFHMKJ_00456 3.4e-73 metI P ABC transporter permease
APDFHMKJ_00457 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APDFHMKJ_00458 1.9e-261 frdC 1.3.5.4 C FAD binding domain
APDFHMKJ_00459 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APDFHMKJ_00460 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
APDFHMKJ_00461 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
APDFHMKJ_00462 5.7e-272 P Sodium:sulfate symporter transmembrane region
APDFHMKJ_00463 1.4e-37 S Putative adhesin
APDFHMKJ_00464 3.7e-261 V ABC transporter transmembrane region
APDFHMKJ_00465 1.1e-139
APDFHMKJ_00466 3.7e-20
APDFHMKJ_00467 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
APDFHMKJ_00468 1.3e-141 yfeO P Voltage gated chloride channel
APDFHMKJ_00469 1.6e-08
APDFHMKJ_00470 1.6e-08
APDFHMKJ_00471 1.4e-83 K FR47-like protein
APDFHMKJ_00472 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
APDFHMKJ_00473 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APDFHMKJ_00474 2.2e-165 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APDFHMKJ_00475 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APDFHMKJ_00476 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APDFHMKJ_00477 1.8e-62 yabR J S1 RNA binding domain
APDFHMKJ_00478 6.8e-60 divIC D Septum formation initiator
APDFHMKJ_00479 2.1e-114 3.6.1.27 I Acid phosphatase homologues
APDFHMKJ_00480 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
APDFHMKJ_00481 0.0 uvrA3 L excinuclease ABC, A subunit
APDFHMKJ_00482 9.9e-82 C Flavodoxin
APDFHMKJ_00483 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APDFHMKJ_00484 3.8e-99 S Tetratricopeptide repeat protein
APDFHMKJ_00485 1.4e-75 S Tetratricopeptide repeat protein
APDFHMKJ_00486 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APDFHMKJ_00487 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
APDFHMKJ_00488 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
APDFHMKJ_00489 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
APDFHMKJ_00490 2.7e-18 M Lysin motif
APDFHMKJ_00491 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APDFHMKJ_00492 9e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APDFHMKJ_00493 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APDFHMKJ_00494 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APDFHMKJ_00495 8.1e-54 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APDFHMKJ_00496 2.9e-165 xerD D recombinase XerD
APDFHMKJ_00497 1e-167 cvfB S S1 domain
APDFHMKJ_00498 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
APDFHMKJ_00499 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APDFHMKJ_00500 0.0 dnaE 2.7.7.7 L DNA polymerase
APDFHMKJ_00501 2.3e-23 S Protein of unknown function (DUF2929)
APDFHMKJ_00502 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
APDFHMKJ_00503 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
APDFHMKJ_00504 1.1e-152 ydjP I Alpha/beta hydrolase family
APDFHMKJ_00505 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
APDFHMKJ_00506 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
APDFHMKJ_00507 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
APDFHMKJ_00508 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
APDFHMKJ_00509 9.3e-72 yeaL S Protein of unknown function (DUF441)
APDFHMKJ_00510 3.5e-21
APDFHMKJ_00511 3.6e-146 cbiQ P cobalt transport
APDFHMKJ_00512 0.0 ykoD P ABC transporter, ATP-binding protein
APDFHMKJ_00513 1.5e-95 S UPF0397 protein
APDFHMKJ_00514 2.9e-66 S Domain of unknown function DUF1828
APDFHMKJ_00515 5.5e-09
APDFHMKJ_00516 1.5e-50
APDFHMKJ_00517 2.6e-177 citR K Putative sugar-binding domain
APDFHMKJ_00518 6.2e-249 yjjP S Putative threonine/serine exporter
APDFHMKJ_00519 1e-95
APDFHMKJ_00520 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
APDFHMKJ_00522 5e-184 3.2.1.18 GH33 M Rib/alpha-like repeat
APDFHMKJ_00523 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
APDFHMKJ_00524 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APDFHMKJ_00526 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
APDFHMKJ_00527 2.4e-43 K Helix-turn-helix
APDFHMKJ_00528 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APDFHMKJ_00529 1.4e-226 pbuX F xanthine permease
APDFHMKJ_00530 2.5e-152 msmR K AraC-like ligand binding domain
APDFHMKJ_00531 4.4e-285 pipD E Dipeptidase
APDFHMKJ_00532 1.3e-47 adk 2.7.4.3 F AAA domain
APDFHMKJ_00533 2.1e-80 K acetyltransferase
APDFHMKJ_00534 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APDFHMKJ_00535 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APDFHMKJ_00536 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APDFHMKJ_00537 4.5e-68 S Domain of unknown function (DUF1934)
APDFHMKJ_00538 8.2e-230 pbuG S permease
APDFHMKJ_00539 8.2e-140 cof S haloacid dehalogenase-like hydrolase
APDFHMKJ_00540 9.4e-72
APDFHMKJ_00541 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
APDFHMKJ_00542 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
APDFHMKJ_00543 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APDFHMKJ_00544 1.4e-126 pgm3 G Phosphoglycerate mutase family
APDFHMKJ_00545 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
APDFHMKJ_00546 0.0 helD 3.6.4.12 L DNA helicase
APDFHMKJ_00547 1.5e-107 glnP P ABC transporter permease
APDFHMKJ_00548 1e-105 glnQ 3.6.3.21 E ABC transporter
APDFHMKJ_00549 1.6e-143 aatB ET ABC transporter substrate-binding protein
APDFHMKJ_00550 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
APDFHMKJ_00551 7.1e-98 E GDSL-like Lipase/Acylhydrolase
APDFHMKJ_00552 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
APDFHMKJ_00553 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APDFHMKJ_00554 8.8e-58 S Peptidase propeptide and YPEB domain
APDFHMKJ_00555 2e-75 S cog cog0433
APDFHMKJ_00556 1.9e-110 F DNA/RNA non-specific endonuclease
APDFHMKJ_00557 2.7e-34 S YSIRK type signal peptide
APDFHMKJ_00559 5.5e-53
APDFHMKJ_00560 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
APDFHMKJ_00561 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APDFHMKJ_00562 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APDFHMKJ_00563 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APDFHMKJ_00564 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
APDFHMKJ_00565 0.0 FbpA K Fibronectin-binding protein
APDFHMKJ_00566 1.1e-66
APDFHMKJ_00567 1.3e-159 degV S EDD domain protein, DegV family
APDFHMKJ_00568 5.3e-80
APDFHMKJ_00569 2e-295 S SLAP domain
APDFHMKJ_00570 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APDFHMKJ_00571 1.6e-171 2.7.1.2 GK ROK family
APDFHMKJ_00572 6.6e-44
APDFHMKJ_00573 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
APDFHMKJ_00574 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
APDFHMKJ_00575 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
APDFHMKJ_00576 8.4e-25 G Peptidase_C39 like family
APDFHMKJ_00577 2.8e-162 M NlpC/P60 family
APDFHMKJ_00578 3.2e-90 G Peptidase_C39 like family
APDFHMKJ_00579 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
APDFHMKJ_00580 2.8e-77 P Cobalt transport protein
APDFHMKJ_00581 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
APDFHMKJ_00582 7.9e-174 K helix_turn_helix, arabinose operon control protein
APDFHMKJ_00583 8.3e-157 htpX O Belongs to the peptidase M48B family
APDFHMKJ_00584 5.1e-96 lemA S LemA family
APDFHMKJ_00585 1.6e-189 ybiR P Citrate transporter
APDFHMKJ_00586 2e-70 S Iron-sulphur cluster biosynthesis
APDFHMKJ_00587 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
APDFHMKJ_00588 1.2e-17
APDFHMKJ_00589 1.1e-07 S Uncharacterised protein family (UPF0236)
APDFHMKJ_00590 4.5e-189 ydaM M Glycosyl transferase
APDFHMKJ_00591 4e-177 G Glycosyl hydrolases family 8
APDFHMKJ_00592 1e-119 yfbR S HD containing hydrolase-like enzyme
APDFHMKJ_00593 6.4e-159 L HNH nucleases
APDFHMKJ_00594 7.3e-148 S Protein of unknown function (DUF805)
APDFHMKJ_00595 3.4e-135 glnQ E ABC transporter, ATP-binding protein
APDFHMKJ_00596 1.3e-290 glnP P ABC transporter permease
APDFHMKJ_00597 8.9e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
APDFHMKJ_00598 5.8e-64 yeaO S Protein of unknown function, DUF488
APDFHMKJ_00599 1.3e-124 terC P Integral membrane protein TerC family
APDFHMKJ_00600 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
APDFHMKJ_00601 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
APDFHMKJ_00602 4.7e-25 S Protein conserved in bacteria
APDFHMKJ_00603 3.9e-57
APDFHMKJ_00604 4.7e-85
APDFHMKJ_00605 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
APDFHMKJ_00606 5.8e-186 XK27_05540 S DUF218 domain
APDFHMKJ_00607 1.1e-110
APDFHMKJ_00608 4.3e-107
APDFHMKJ_00609 1.2e-139 yicL EG EamA-like transporter family
APDFHMKJ_00610 5e-165 EG EamA-like transporter family
APDFHMKJ_00611 6.2e-163 EG EamA-like transporter family
APDFHMKJ_00612 2e-32
APDFHMKJ_00613 7.8e-38
APDFHMKJ_00614 2.6e-155
APDFHMKJ_00617 1.8e-81 M NlpC/P60 family
APDFHMKJ_00618 2.1e-131 cobQ S glutamine amidotransferase
APDFHMKJ_00619 6.5e-64 L RelB antitoxin
APDFHMKJ_00620 1.1e-75 V ABC transporter transmembrane region
APDFHMKJ_00621 3.5e-222 L transposase, IS605 OrfB family
APDFHMKJ_00622 6.1e-136 V ABC transporter transmembrane region
APDFHMKJ_00623 1.7e-184 G Transmembrane secretion effector
APDFHMKJ_00624 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APDFHMKJ_00625 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APDFHMKJ_00626 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
APDFHMKJ_00627 1.4e-210 yttB EGP Major facilitator Superfamily
APDFHMKJ_00628 0.0 pepO 3.4.24.71 O Peptidase family M13
APDFHMKJ_00629 0.0 kup P Transport of potassium into the cell
APDFHMKJ_00630 7.3e-74
APDFHMKJ_00631 2.1e-45 S PFAM Archaeal ATPase
APDFHMKJ_00633 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
APDFHMKJ_00634 5.9e-45
APDFHMKJ_00635 4.8e-28
APDFHMKJ_00638 4.3e-67 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_00639 3.3e-147 malG P ABC transporter permease
APDFHMKJ_00640 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
APDFHMKJ_00641 5e-213 malE G Bacterial extracellular solute-binding protein
APDFHMKJ_00642 6.8e-209 msmX P Belongs to the ABC transporter superfamily
APDFHMKJ_00643 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
APDFHMKJ_00644 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
APDFHMKJ_00645 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
APDFHMKJ_00646 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
APDFHMKJ_00647 0.0 fhaB M Rib/alpha-like repeat
APDFHMKJ_00648 5.8e-160 V ABC transporter transmembrane region
APDFHMKJ_00649 7e-68 V ABC transporter transmembrane region
APDFHMKJ_00650 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
APDFHMKJ_00651 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
APDFHMKJ_00652 2.5e-72 S Peptidase propeptide and YPEB domain
APDFHMKJ_00653 3.4e-76 S Peptidase propeptide and YPEB domain
APDFHMKJ_00654 5.2e-187 T GHKL domain
APDFHMKJ_00655 3.1e-130 T Transcriptional regulatory protein, C terminal
APDFHMKJ_00656 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
APDFHMKJ_00657 2.9e-277 V ABC transporter transmembrane region
APDFHMKJ_00659 3.7e-13
APDFHMKJ_00660 3.1e-12
APDFHMKJ_00661 3.7e-18 ps115 K sequence-specific DNA binding
APDFHMKJ_00662 4.7e-15 S Pfam:Peptidase_M78
APDFHMKJ_00663 1.2e-54 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
APDFHMKJ_00664 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
APDFHMKJ_00665 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
APDFHMKJ_00666 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APDFHMKJ_00667 0.0 lacZ 3.2.1.23 G -beta-galactosidase
APDFHMKJ_00668 5.7e-103 lacS G Transporter
APDFHMKJ_00669 8.9e-207 lacS G Transporter
APDFHMKJ_00670 5.4e-165 lacR K Transcriptional regulator
APDFHMKJ_00671 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
APDFHMKJ_00672 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
APDFHMKJ_00673 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
APDFHMKJ_00674 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
APDFHMKJ_00675 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
APDFHMKJ_00676 2e-106 K Transcriptional regulator, AbiEi antitoxin
APDFHMKJ_00677 1.2e-188 K Periplasmic binding protein-like domain
APDFHMKJ_00679 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APDFHMKJ_00680 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
APDFHMKJ_00681 3.8e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
APDFHMKJ_00682 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APDFHMKJ_00683 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APDFHMKJ_00684 2e-52 yaaQ S Cyclic-di-AMP receptor
APDFHMKJ_00685 6.3e-154 holB 2.7.7.7 L DNA polymerase III
APDFHMKJ_00686 1.8e-59 yabA L Involved in initiation control of chromosome replication
APDFHMKJ_00687 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APDFHMKJ_00688 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
APDFHMKJ_00689 2.2e-85 S ECF transporter, substrate-specific component
APDFHMKJ_00690 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
APDFHMKJ_00691 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
APDFHMKJ_00692 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APDFHMKJ_00693 1.9e-245 L Transposase IS66 family
APDFHMKJ_00694 8.7e-34 S Transposase C of IS166 homeodomain
APDFHMKJ_00695 9.3e-64 L PFAM IS66 Orf2 family protein
APDFHMKJ_00696 7.7e-22
APDFHMKJ_00697 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
APDFHMKJ_00698 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
APDFHMKJ_00699 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
APDFHMKJ_00700 0.0 uup S ABC transporter, ATP-binding protein
APDFHMKJ_00701 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APDFHMKJ_00702 0.0 clpE O Belongs to the ClpA ClpB family
APDFHMKJ_00703 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
APDFHMKJ_00704 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
APDFHMKJ_00705 1.4e-140 hlyX S Transporter associated domain
APDFHMKJ_00706 2.7e-74
APDFHMKJ_00707 1.6e-85
APDFHMKJ_00708 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
APDFHMKJ_00709 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APDFHMKJ_00710 1.4e-118 D Alpha beta
APDFHMKJ_00711 8.3e-24 papP P ABC transporter, permease protein
APDFHMKJ_00713 4.5e-58 yodB K Transcriptional regulator, HxlR family
APDFHMKJ_00714 2.2e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APDFHMKJ_00715 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
APDFHMKJ_00716 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APDFHMKJ_00717 5.7e-83 S Aminoacyl-tRNA editing domain
APDFHMKJ_00718 6.1e-224 S SLAP domain
APDFHMKJ_00719 1.5e-97 S CAAX protease self-immunity
APDFHMKJ_00720 1e-12
APDFHMKJ_00721 1.3e-277 arlS 2.7.13.3 T Histidine kinase
APDFHMKJ_00722 1.2e-126 K response regulator
APDFHMKJ_00723 4.7e-97 yceD S Uncharacterized ACR, COG1399
APDFHMKJ_00724 4.6e-216 ylbM S Belongs to the UPF0348 family
APDFHMKJ_00725 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APDFHMKJ_00726 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
APDFHMKJ_00727 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APDFHMKJ_00728 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
APDFHMKJ_00729 4.2e-84 yqeG S HAD phosphatase, family IIIA
APDFHMKJ_00730 8.6e-199 tnpB L Putative transposase DNA-binding domain
APDFHMKJ_00731 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
APDFHMKJ_00732 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APDFHMKJ_00733 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
APDFHMKJ_00734 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APDFHMKJ_00735 2.7e-36 yyaR K Acetyltransferase (GNAT) domain
APDFHMKJ_00738 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
APDFHMKJ_00739 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
APDFHMKJ_00740 1.8e-230 steT_1 E amino acid
APDFHMKJ_00741 2.2e-139 puuD S peptidase C26
APDFHMKJ_00743 2.4e-172 V HNH endonuclease
APDFHMKJ_00744 6.4e-135 S PFAM Archaeal ATPase
APDFHMKJ_00745 9.2e-248 yifK E Amino acid permease
APDFHMKJ_00746 9.7e-234 cycA E Amino acid permease
APDFHMKJ_00747 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
APDFHMKJ_00748 0.0 clpE O AAA domain (Cdc48 subfamily)
APDFHMKJ_00749 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
APDFHMKJ_00750 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APDFHMKJ_00751 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
APDFHMKJ_00752 0.0 XK27_06780 V ABC transporter permease
APDFHMKJ_00753 1.9e-36
APDFHMKJ_00754 7.9e-291 ytgP S Polysaccharide biosynthesis protein
APDFHMKJ_00755 2.7e-137 lysA2 M Glycosyl hydrolases family 25
APDFHMKJ_00756 2.3e-133 S Protein of unknown function (DUF975)
APDFHMKJ_00757 7.6e-177 pbpX2 V Beta-lactamase
APDFHMKJ_00758 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APDFHMKJ_00759 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APDFHMKJ_00760 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
APDFHMKJ_00761 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APDFHMKJ_00762 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
APDFHMKJ_00763 4.1e-44
APDFHMKJ_00764 1e-207 ywhK S Membrane
APDFHMKJ_00765 7.4e-80 ykuL S (CBS) domain
APDFHMKJ_00766 0.0 cadA P P-type ATPase
APDFHMKJ_00767 2.8e-205 napA P Sodium/hydrogen exchanger family
APDFHMKJ_00768 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
APDFHMKJ_00769 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
APDFHMKJ_00770 4.1e-276 V ABC transporter transmembrane region
APDFHMKJ_00771 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
APDFHMKJ_00772 5.4e-51
APDFHMKJ_00773 4.2e-154 EGP Major facilitator Superfamily
APDFHMKJ_00774 3e-111 ropB K Transcriptional regulator
APDFHMKJ_00775 2.7e-120 S CAAX protease self-immunity
APDFHMKJ_00776 1.6e-194 S DUF218 domain
APDFHMKJ_00777 0.0 macB_3 V ABC transporter, ATP-binding protein
APDFHMKJ_00778 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
APDFHMKJ_00779 2.8e-100 S ECF transporter, substrate-specific component
APDFHMKJ_00780 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
APDFHMKJ_00781 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
APDFHMKJ_00782 1.3e-282 xylG 3.6.3.17 S ABC transporter
APDFHMKJ_00783 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
APDFHMKJ_00784 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
APDFHMKJ_00785 4.8e-145 yeaE S Aldo/keto reductase family
APDFHMKJ_00786 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APDFHMKJ_00787 2.1e-168 dnaI L Primosomal protein DnaI
APDFHMKJ_00788 5.1e-251 dnaB L Replication initiation and membrane attachment
APDFHMKJ_00789 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APDFHMKJ_00790 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APDFHMKJ_00791 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APDFHMKJ_00792 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APDFHMKJ_00793 3.5e-25 qmcA O prohibitin homologues
APDFHMKJ_00794 7.4e-105 qmcA O prohibitin homologues
APDFHMKJ_00795 8e-51 L RelB antitoxin
APDFHMKJ_00796 4.5e-188 S Bacteriocin helveticin-J
APDFHMKJ_00797 4.4e-283 M Peptidase family M1 domain
APDFHMKJ_00798 1.8e-176 S SLAP domain
APDFHMKJ_00799 6.9e-218 mepA V MATE efflux family protein
APDFHMKJ_00800 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
APDFHMKJ_00801 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APDFHMKJ_00802 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APDFHMKJ_00804 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APDFHMKJ_00805 6.5e-221 ecsB U ABC transporter
APDFHMKJ_00806 5.7e-135 ecsA V ABC transporter, ATP-binding protein
APDFHMKJ_00807 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
APDFHMKJ_00808 3.9e-25
APDFHMKJ_00809 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APDFHMKJ_00810 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
APDFHMKJ_00811 1.1e-265
APDFHMKJ_00812 3.9e-31 S Domain of unknown function DUF1829
APDFHMKJ_00813 1.7e-22 blpT
APDFHMKJ_00814 4.6e-27 S Enterocin A Immunity
APDFHMKJ_00817 1.3e-69 doc S Prophage maintenance system killer protein
APDFHMKJ_00818 2.9e-31
APDFHMKJ_00819 0.0 pepF E oligoendopeptidase F
APDFHMKJ_00820 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
APDFHMKJ_00821 1.8e-111 S Protein of unknown function (DUF554)
APDFHMKJ_00822 1.2e-30
APDFHMKJ_00823 1.4e-34
APDFHMKJ_00824 5e-72 rimL J Acetyltransferase (GNAT) domain
APDFHMKJ_00825 8.3e-58
APDFHMKJ_00826 8.9e-292 S ABC transporter
APDFHMKJ_00827 2.4e-136 thrE S Putative threonine/serine exporter
APDFHMKJ_00828 1.1e-83 S Threonine/Serine exporter, ThrE
APDFHMKJ_00829 9.1e-112 yvpB S Peptidase_C39 like family
APDFHMKJ_00830 2.5e-68
APDFHMKJ_00831 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APDFHMKJ_00832 5.5e-77 nrdI F NrdI Flavodoxin like
APDFHMKJ_00833 4.7e-221 tnpB L Putative transposase DNA-binding domain
APDFHMKJ_00834 3.3e-112
APDFHMKJ_00835 2.9e-279 S O-antigen ligase like membrane protein
APDFHMKJ_00836 3.9e-42
APDFHMKJ_00837 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
APDFHMKJ_00838 5e-88 M NlpC/P60 family
APDFHMKJ_00839 1.4e-136 M NlpC P60 family protein
APDFHMKJ_00840 2.6e-118 M NlpC/P60 family
APDFHMKJ_00841 1.6e-41
APDFHMKJ_00842 3.5e-175 S Cysteine-rich secretory protein family
APDFHMKJ_00843 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APDFHMKJ_00844 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
APDFHMKJ_00846 2e-178 MA20_14895 S Conserved hypothetical protein 698
APDFHMKJ_00847 1.1e-83 dps P Belongs to the Dps family
APDFHMKJ_00848 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
APDFHMKJ_00849 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
APDFHMKJ_00850 1.8e-58 S Putative adhesin
APDFHMKJ_00851 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
APDFHMKJ_00852 2e-234 mepA V MATE efflux family protein
APDFHMKJ_00853 3.9e-33 I Carboxylesterase family
APDFHMKJ_00854 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
APDFHMKJ_00855 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
APDFHMKJ_00856 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
APDFHMKJ_00857 1.7e-148 S haloacid dehalogenase-like hydrolase
APDFHMKJ_00858 7e-50
APDFHMKJ_00859 1.9e-37
APDFHMKJ_00860 1.2e-63 S Alpha beta hydrolase
APDFHMKJ_00861 1e-23 S Alpha beta hydrolase
APDFHMKJ_00862 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
APDFHMKJ_00863 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APDFHMKJ_00864 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APDFHMKJ_00865 2.2e-292 I Acyltransferase
APDFHMKJ_00866 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APDFHMKJ_00867 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
APDFHMKJ_00868 3.8e-15 S Domain of Unknown Function with PDB structure (DUF3850)
APDFHMKJ_00870 2.9e-12
APDFHMKJ_00871 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
APDFHMKJ_00872 1e-205 M Glycosyl hydrolases family 25
APDFHMKJ_00873 2.8e-157 cinI S Serine hydrolase (FSH1)
APDFHMKJ_00874 4.3e-298 S Predicted membrane protein (DUF2207)
APDFHMKJ_00875 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
APDFHMKJ_00877 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
APDFHMKJ_00878 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APDFHMKJ_00879 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
APDFHMKJ_00880 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
APDFHMKJ_00881 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
APDFHMKJ_00882 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APDFHMKJ_00883 3.4e-71 yqhY S Asp23 family, cell envelope-related function
APDFHMKJ_00884 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APDFHMKJ_00885 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APDFHMKJ_00886 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APDFHMKJ_00887 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APDFHMKJ_00888 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APDFHMKJ_00889 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
APDFHMKJ_00890 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
APDFHMKJ_00891 1.1e-77 6.3.3.2 S ASCH
APDFHMKJ_00892 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
APDFHMKJ_00893 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APDFHMKJ_00894 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APDFHMKJ_00895 2.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APDFHMKJ_00896 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APDFHMKJ_00897 1.1e-138 stp 3.1.3.16 T phosphatase
APDFHMKJ_00898 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
APDFHMKJ_00899 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APDFHMKJ_00900 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
APDFHMKJ_00901 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
APDFHMKJ_00902 1.4e-30
APDFHMKJ_00903 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
APDFHMKJ_00904 1.5e-56 asp S Asp23 family, cell envelope-related function
APDFHMKJ_00905 7.6e-305 yloV S DAK2 domain fusion protein YloV
APDFHMKJ_00906 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APDFHMKJ_00907 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APDFHMKJ_00908 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APDFHMKJ_00909 3.1e-192 oppD P Belongs to the ABC transporter superfamily
APDFHMKJ_00910 1.5e-170 oppF P Belongs to the ABC transporter superfamily
APDFHMKJ_00911 2.6e-172 oppB P ABC transporter permease
APDFHMKJ_00912 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
APDFHMKJ_00913 9.7e-46 oppA E ABC transporter substrate-binding protein
APDFHMKJ_00914 1.3e-229 S Putative peptidoglycan binding domain
APDFHMKJ_00915 7.5e-95 S ECF-type riboflavin transporter, S component
APDFHMKJ_00916 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
APDFHMKJ_00917 9.3e-204 pbpX1 V Beta-lactamase
APDFHMKJ_00918 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
APDFHMKJ_00919 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APDFHMKJ_00920 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
APDFHMKJ_00944 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
APDFHMKJ_00945 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
APDFHMKJ_00946 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APDFHMKJ_00947 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APDFHMKJ_00948 1.7e-29 secG U Preprotein translocase
APDFHMKJ_00949 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APDFHMKJ_00950 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
APDFHMKJ_00951 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
APDFHMKJ_00952 1.4e-16 L Transposase
APDFHMKJ_00953 1.9e-12 L Transposase
APDFHMKJ_00954 1.3e-55 K Acetyltransferase (GNAT) domain
APDFHMKJ_00955 1.2e-10
APDFHMKJ_00956 2.8e-65 K LytTr DNA-binding domain
APDFHMKJ_00957 1.2e-49 S Protein of unknown function (DUF3021)
APDFHMKJ_00958 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
APDFHMKJ_00959 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
APDFHMKJ_00960 6e-132 S membrane transporter protein
APDFHMKJ_00961 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
APDFHMKJ_00962 7.3e-161 czcD P cation diffusion facilitator family transporter
APDFHMKJ_00963 1.4e-23
APDFHMKJ_00964 1.2e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APDFHMKJ_00965 1.1e-183 S AAA domain
APDFHMKJ_00966 3.9e-267 pepC 3.4.22.40 E Peptidase C1-like family
APDFHMKJ_00967 1.9e-52
APDFHMKJ_00968 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
APDFHMKJ_00969 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APDFHMKJ_00970 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APDFHMKJ_00971 2.9e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
APDFHMKJ_00972 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APDFHMKJ_00973 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APDFHMKJ_00974 5.5e-95 sigH K Belongs to the sigma-70 factor family
APDFHMKJ_00975 1.7e-34
APDFHMKJ_00976 5.8e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
APDFHMKJ_00977 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APDFHMKJ_00978 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APDFHMKJ_00979 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
APDFHMKJ_00980 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APDFHMKJ_00981 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APDFHMKJ_00982 2.8e-157 pstS P Phosphate
APDFHMKJ_00983 3.9e-163 pstC P probably responsible for the translocation of the substrate across the membrane
APDFHMKJ_00984 1.2e-155 pstA P Phosphate transport system permease protein PstA
APDFHMKJ_00985 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APDFHMKJ_00986 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APDFHMKJ_00987 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
APDFHMKJ_00988 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APDFHMKJ_00989 1.8e-104 3.2.2.20 K acetyltransferase
APDFHMKJ_00991 4.3e-226 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APDFHMKJ_00992 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
APDFHMKJ_00993 4.1e-21 K Helix-turn-helix domain, rpiR family
APDFHMKJ_00994 1.3e-71 K Helix-turn-helix domain, rpiR family
APDFHMKJ_00995 1.1e-56 S Protein of unknown function (DUF3290)
APDFHMKJ_00996 3e-116 yviA S Protein of unknown function (DUF421)
APDFHMKJ_00997 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
APDFHMKJ_00998 8e-182 dnaQ 2.7.7.7 L EXOIII
APDFHMKJ_00999 1.9e-158 endA F DNA RNA non-specific endonuclease
APDFHMKJ_01000 1.3e-281 pipD E Dipeptidase
APDFHMKJ_01001 1.9e-203 malK P ATPases associated with a variety of cellular activities
APDFHMKJ_01002 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
APDFHMKJ_01003 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
APDFHMKJ_01004 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
APDFHMKJ_01005 2.3e-240 G Bacterial extracellular solute-binding protein
APDFHMKJ_01006 1.8e-154 corA P CorA-like Mg2+ transporter protein
APDFHMKJ_01007 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
APDFHMKJ_01008 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
APDFHMKJ_01009 0.0 ydgH S MMPL family
APDFHMKJ_01011 7.8e-26 K Acetyltransferase (GNAT) domain
APDFHMKJ_01012 1.8e-163
APDFHMKJ_01013 1.2e-299 I Protein of unknown function (DUF2974)
APDFHMKJ_01014 2.1e-194 pbpX1 V Beta-lactamase
APDFHMKJ_01015 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APDFHMKJ_01016 2.7e-216 aspC 2.6.1.1 E Aminotransferase
APDFHMKJ_01017 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APDFHMKJ_01018 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APDFHMKJ_01019 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APDFHMKJ_01020 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APDFHMKJ_01021 1.8e-245 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APDFHMKJ_01022 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
APDFHMKJ_01023 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APDFHMKJ_01024 3.4e-175 yjeM E Amino Acid
APDFHMKJ_01025 7.8e-39 yjeM E Amino Acid
APDFHMKJ_01026 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
APDFHMKJ_01027 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APDFHMKJ_01028 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APDFHMKJ_01029 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APDFHMKJ_01030 1.3e-148
APDFHMKJ_01031 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APDFHMKJ_01032 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APDFHMKJ_01033 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
APDFHMKJ_01034 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
APDFHMKJ_01035 0.0 comEC S Competence protein ComEC
APDFHMKJ_01036 3.1e-79 comEA L Competence protein ComEA
APDFHMKJ_01037 2.4e-187 ylbL T Belongs to the peptidase S16 family
APDFHMKJ_01038 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APDFHMKJ_01039 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
APDFHMKJ_01040 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
APDFHMKJ_01041 5.9e-211 ftsW D Belongs to the SEDS family
APDFHMKJ_01042 0.0 typA T GTP-binding protein TypA
APDFHMKJ_01043 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APDFHMKJ_01044 3.5e-32 ykzG S Belongs to the UPF0356 family
APDFHMKJ_01045 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APDFHMKJ_01046 2.4e-73 S cog cog1373
APDFHMKJ_01047 5.6e-179 S PFAM Archaeal ATPase
APDFHMKJ_01048 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
APDFHMKJ_01049 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
APDFHMKJ_01050 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APDFHMKJ_01051 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APDFHMKJ_01052 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APDFHMKJ_01053 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APDFHMKJ_01054 2.5e-39 rpmE2 J Ribosomal protein L31
APDFHMKJ_01055 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
APDFHMKJ_01056 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
APDFHMKJ_01057 9.5e-297 ybeC E amino acid
APDFHMKJ_01058 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APDFHMKJ_01059 2.1e-42
APDFHMKJ_01060 1.4e-51
APDFHMKJ_01061 8.4e-56 S Domain of unknown function (DUF4767)
APDFHMKJ_01062 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APDFHMKJ_01063 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
APDFHMKJ_01064 3.2e-101 3.6.1.27 I Acid phosphatase homologues
APDFHMKJ_01065 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
APDFHMKJ_01066 1e-79 S AAA domain
APDFHMKJ_01067 3.3e-61 3.6.1.55 F NUDIX domain
APDFHMKJ_01068 6e-46 L An automated process has identified a potential problem with this gene model
APDFHMKJ_01069 2.8e-48 S Peptidase propeptide and YPEB domain
APDFHMKJ_01070 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
APDFHMKJ_01071 0.0 S SH3-like domain
APDFHMKJ_01072 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APDFHMKJ_01073 2.1e-171 whiA K May be required for sporulation
APDFHMKJ_01074 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
APDFHMKJ_01075 6.2e-165 rapZ S Displays ATPase and GTPase activities
APDFHMKJ_01076 4.1e-90 S Short repeat of unknown function (DUF308)
APDFHMKJ_01077 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APDFHMKJ_01078 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APDFHMKJ_01079 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
APDFHMKJ_01080 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APDFHMKJ_01081 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
APDFHMKJ_01082 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APDFHMKJ_01083 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APDFHMKJ_01084 5.1e-17
APDFHMKJ_01085 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APDFHMKJ_01086 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APDFHMKJ_01087 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APDFHMKJ_01088 2.4e-128 S cog cog1373
APDFHMKJ_01089 1.4e-109 yniG EGP Major facilitator Superfamily
APDFHMKJ_01090 5.4e-237 L transposase, IS605 OrfB family
APDFHMKJ_01091 4.5e-76 yniG EGP Major facilitator Superfamily
APDFHMKJ_01092 4.9e-35
APDFHMKJ_01094 1.3e-42
APDFHMKJ_01095 1.9e-75 M LysM domain
APDFHMKJ_01096 6e-21 K Putative DNA-binding domain
APDFHMKJ_01097 7.6e-239 pyrP F Permease
APDFHMKJ_01098 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APDFHMKJ_01099 9.2e-262 emrY EGP Major facilitator Superfamily
APDFHMKJ_01100 9.7e-83 S An automated process has identified a potential problem with this gene model
APDFHMKJ_01101 1e-137 S Protein of unknown function (DUF3100)
APDFHMKJ_01102 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
APDFHMKJ_01103 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
APDFHMKJ_01104 0.0 oppA E ABC transporter
APDFHMKJ_01105 1.4e-147 S Sucrose-6F-phosphate phosphohydrolase
APDFHMKJ_01106 0.0 mco Q Multicopper oxidase
APDFHMKJ_01107 1.9e-25
APDFHMKJ_01108 7.1e-158 metQ1 P Belongs to the nlpA lipoprotein family
APDFHMKJ_01109 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
APDFHMKJ_01110 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APDFHMKJ_01111 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APDFHMKJ_01112 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APDFHMKJ_01113 1e-156 cjaA ET ABC transporter substrate-binding protein
APDFHMKJ_01114 1.5e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APDFHMKJ_01115 5.3e-116 P ABC transporter permease
APDFHMKJ_01116 9.1e-54 papP P ABC transporter, permease protein
APDFHMKJ_01117 2.9e-15 M LysM domain protein
APDFHMKJ_01118 3.8e-48 M LysM domain protein
APDFHMKJ_01119 1.4e-86 C Aldo keto reductase
APDFHMKJ_01120 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
APDFHMKJ_01121 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
APDFHMKJ_01122 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
APDFHMKJ_01123 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
APDFHMKJ_01124 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APDFHMKJ_01125 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APDFHMKJ_01126 5.8e-152 dprA LU DNA protecting protein DprA
APDFHMKJ_01127 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APDFHMKJ_01128 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APDFHMKJ_01129 1.9e-94 yjcE P Sodium proton antiporter
APDFHMKJ_01130 1.5e-40 yjcE P Sodium proton antiporter
APDFHMKJ_01131 1.1e-66 yjcE P NhaP-type Na H and K H
APDFHMKJ_01132 7.1e-36 yozE S Belongs to the UPF0346 family
APDFHMKJ_01133 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
APDFHMKJ_01134 1.2e-107 hlyIII S protein, hemolysin III
APDFHMKJ_01135 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APDFHMKJ_01136 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APDFHMKJ_01137 4.3e-86 3.4.21.96 S SLAP domain
APDFHMKJ_01138 8.4e-128 yagE E Amino acid permease
APDFHMKJ_01139 9.7e-65 yagE E amino acid
APDFHMKJ_01140 9e-121
APDFHMKJ_01141 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
APDFHMKJ_01142 3.9e-186 S Putative peptidoglycan binding domain
APDFHMKJ_01143 4e-16
APDFHMKJ_01144 7.9e-92 liaI S membrane
APDFHMKJ_01145 6.6e-70 XK27_02470 K LytTr DNA-binding domain
APDFHMKJ_01146 1.2e-18 S Sugar efflux transporter for intercellular exchange
APDFHMKJ_01147 1.3e-250 dtpT U amino acid peptide transporter
APDFHMKJ_01148 0.0 pepN 3.4.11.2 E aminopeptidase
APDFHMKJ_01149 2.8e-47 lysM M LysM domain
APDFHMKJ_01150 1.3e-174
APDFHMKJ_01151 1.7e-152 mdtG EGP Major facilitator Superfamily
APDFHMKJ_01152 6.9e-47 mdtG EGP Major facilitator Superfamily
APDFHMKJ_01153 6.4e-243 cydA 1.10.3.14 C ubiquinol oxidase
APDFHMKJ_01154 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
APDFHMKJ_01155 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
APDFHMKJ_01156 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
APDFHMKJ_01157 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APDFHMKJ_01158 9.7e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APDFHMKJ_01159 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
APDFHMKJ_01160 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
APDFHMKJ_01161 6.2e-43 1.3.5.4 C FAD binding domain
APDFHMKJ_01162 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APDFHMKJ_01163 2.8e-168 K LysR substrate binding domain
APDFHMKJ_01164 1.1e-121 3.6.1.27 I Acid phosphatase homologues
APDFHMKJ_01165 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
APDFHMKJ_01166 4.7e-275 ytgP S Polysaccharide biosynthesis protein
APDFHMKJ_01167 1.4e-191 oppA E ABC transporter, substratebinding protein
APDFHMKJ_01168 1.3e-30
APDFHMKJ_01169 1.2e-144 pstS P Phosphate
APDFHMKJ_01170 2.1e-160 pstC P probably responsible for the translocation of the substrate across the membrane
APDFHMKJ_01171 1.2e-152 pstA P Phosphate transport system permease protein PstA
APDFHMKJ_01172 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APDFHMKJ_01173 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
APDFHMKJ_01174 9.5e-121 T Transcriptional regulatory protein, C terminal
APDFHMKJ_01175 1.1e-282 phoR 2.7.13.3 T Histidine kinase
APDFHMKJ_01176 1.4e-31 O OsmC-like protein
APDFHMKJ_01178 1.5e-36 oppA E ABC transporter substrate-binding protein
APDFHMKJ_01179 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APDFHMKJ_01180 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
APDFHMKJ_01181 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APDFHMKJ_01182 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APDFHMKJ_01183 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APDFHMKJ_01184 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APDFHMKJ_01185 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
APDFHMKJ_01187 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
APDFHMKJ_01190 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APDFHMKJ_01191 8.5e-260 qacA EGP Major facilitator Superfamily
APDFHMKJ_01192 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
APDFHMKJ_01193 1.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APDFHMKJ_01194 1.8e-119 S Putative esterase
APDFHMKJ_01195 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
APDFHMKJ_01196 3.4e-195 S Bacterial protein of unknown function (DUF871)
APDFHMKJ_01197 3.7e-130 ybbH_2 K rpiR family
APDFHMKJ_01198 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
APDFHMKJ_01199 8.4e-265 S Fibronectin type III domain
APDFHMKJ_01200 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APDFHMKJ_01202 4.6e-257 pepC 3.4.22.40 E aminopeptidase
APDFHMKJ_01203 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
APDFHMKJ_01204 5e-301 oppA E ABC transporter, substratebinding protein
APDFHMKJ_01205 1.6e-310 oppA E ABC transporter, substratebinding protein
APDFHMKJ_01206 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
APDFHMKJ_01207 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
APDFHMKJ_01208 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
APDFHMKJ_01209 5.9e-09
APDFHMKJ_01210 4.4e-43
APDFHMKJ_01211 8.7e-66 2.7.1.191 G PTS system fructose IIA component
APDFHMKJ_01212 0.0 3.6.3.8 P P-type ATPase
APDFHMKJ_01213 4.9e-125
APDFHMKJ_01214 1.2e-241 S response to antibiotic
APDFHMKJ_01215 0.0 L Plasmid pRiA4b ORF-3-like protein
APDFHMKJ_01216 4.7e-159 D nuclear chromosome segregation
APDFHMKJ_01217 1.2e-105 G Phosphoglycerate mutase family
APDFHMKJ_01218 2.6e-89 G Histidine phosphatase superfamily (branch 1)
APDFHMKJ_01219 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
APDFHMKJ_01220 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APDFHMKJ_01222 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
APDFHMKJ_01224 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
APDFHMKJ_01225 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
APDFHMKJ_01226 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
APDFHMKJ_01227 4.4e-144 K SIS domain
APDFHMKJ_01228 6.7e-228 slpX S SLAP domain
APDFHMKJ_01229 1.3e-22 3.6.4.12 S transposase or invertase
APDFHMKJ_01230 6.6e-11
APDFHMKJ_01231 3.2e-240 npr 1.11.1.1 C NADH oxidase
APDFHMKJ_01234 4.4e-239 oppA2 E ABC transporter, substratebinding protein
APDFHMKJ_01235 3.4e-45 oppA2 E ABC transporter, substratebinding protein
APDFHMKJ_01236 3.3e-179
APDFHMKJ_01237 4.6e-123 gntR1 K UTRA
APDFHMKJ_01238 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
APDFHMKJ_01239 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
APDFHMKJ_01240 1.7e-204 csaB M Glycosyl transferases group 1
APDFHMKJ_01241 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APDFHMKJ_01242 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APDFHMKJ_01243 1.4e-204 tnpB L Putative transposase DNA-binding domain
APDFHMKJ_01244 0.0 pacL 3.6.3.8 P P-type ATPase
APDFHMKJ_01245 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APDFHMKJ_01246 3e-257 epsU S Polysaccharide biosynthesis protein
APDFHMKJ_01247 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
APDFHMKJ_01248 4.1e-83 ydcK S Belongs to the SprT family
APDFHMKJ_01250 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
APDFHMKJ_01251 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
APDFHMKJ_01252 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APDFHMKJ_01253 5.8e-203 camS S sex pheromone
APDFHMKJ_01254 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APDFHMKJ_01255 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APDFHMKJ_01256 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APDFHMKJ_01257 2.7e-171 yegS 2.7.1.107 G Lipid kinase
APDFHMKJ_01258 4.3e-108 ybhL S Belongs to the BI1 family
APDFHMKJ_01259 2.6e-57
APDFHMKJ_01260 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
APDFHMKJ_01261 2.8e-244 nhaC C Na H antiporter NhaC
APDFHMKJ_01262 6.3e-201 pbpX V Beta-lactamase
APDFHMKJ_01263 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APDFHMKJ_01264 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
APDFHMKJ_01269 1.9e-259 emrY EGP Major facilitator Superfamily
APDFHMKJ_01270 2e-91 yxdD K Bacterial regulatory proteins, tetR family
APDFHMKJ_01271 0.0 4.2.1.53 S Myosin-crossreactive antigen
APDFHMKJ_01272 5.5e-148 S cog cog1373
APDFHMKJ_01273 1.9e-138 2.4.2.3 F Phosphorylase superfamily
APDFHMKJ_01274 9e-144 2.4.2.3 F Phosphorylase superfamily
APDFHMKJ_01275 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
APDFHMKJ_01276 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
APDFHMKJ_01277 6.8e-116 dedA S SNARE-like domain protein
APDFHMKJ_01278 3.7e-100 S Protein of unknown function (DUF1461)
APDFHMKJ_01279 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APDFHMKJ_01280 2.1e-92 yutD S Protein of unknown function (DUF1027)
APDFHMKJ_01281 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
APDFHMKJ_01282 4.3e-55
APDFHMKJ_01283 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APDFHMKJ_01284 3.2e-181 ccpA K catabolite control protein A
APDFHMKJ_01285 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
APDFHMKJ_01286 1.3e-36
APDFHMKJ_01287 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APDFHMKJ_01288 3.7e-146 ykuT M mechanosensitive ion channel
APDFHMKJ_01289 6.9e-100 V ATPases associated with a variety of cellular activities
APDFHMKJ_01290 1.7e-139
APDFHMKJ_01291 5.4e-113
APDFHMKJ_01292 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APDFHMKJ_01293 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APDFHMKJ_01294 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APDFHMKJ_01295 2.3e-309 oppA3 E ABC transporter, substratebinding protein
APDFHMKJ_01296 2.4e-60 ypaA S Protein of unknown function (DUF1304)
APDFHMKJ_01297 2.1e-28 S Peptidase propeptide and YPEB domain
APDFHMKJ_01298 7.1e-237 L transposase, IS605 OrfB family
APDFHMKJ_01299 1.1e-286 clcA P chloride
APDFHMKJ_01300 4e-32 E Zn peptidase
APDFHMKJ_01301 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_01302 1.2e-44
APDFHMKJ_01303 9.1e-106 S Bacteriocin helveticin-J
APDFHMKJ_01304 1.3e-117 S SLAP domain
APDFHMKJ_01305 3.5e-136 S SLAP domain
APDFHMKJ_01306 8e-210
APDFHMKJ_01307 1.2e-18
APDFHMKJ_01308 7.3e-175 EGP Sugar (and other) transporter
APDFHMKJ_01309 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
APDFHMKJ_01310 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
APDFHMKJ_01311 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
APDFHMKJ_01312 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
APDFHMKJ_01313 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
APDFHMKJ_01314 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
APDFHMKJ_01315 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APDFHMKJ_01316 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
APDFHMKJ_01317 1.6e-227 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
APDFHMKJ_01318 6e-29 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
APDFHMKJ_01319 9.7e-169
APDFHMKJ_01320 7.5e-143
APDFHMKJ_01321 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
APDFHMKJ_01322 1.4e-26
APDFHMKJ_01323 6.7e-145
APDFHMKJ_01324 5.1e-137
APDFHMKJ_01325 4.5e-141
APDFHMKJ_01326 9.6e-124 skfE V ATPases associated with a variety of cellular activities
APDFHMKJ_01327 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
APDFHMKJ_01328 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
APDFHMKJ_01329 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APDFHMKJ_01330 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
APDFHMKJ_01331 4.8e-81 mutT 3.6.1.55 F NUDIX domain
APDFHMKJ_01332 1.4e-127 S Peptidase family M23
APDFHMKJ_01333 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APDFHMKJ_01334 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APDFHMKJ_01335 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
APDFHMKJ_01336 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
APDFHMKJ_01337 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
APDFHMKJ_01338 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APDFHMKJ_01339 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APDFHMKJ_01340 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
APDFHMKJ_01341 3.5e-71 yqeY S YqeY-like protein
APDFHMKJ_01342 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
APDFHMKJ_01343 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
APDFHMKJ_01344 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
APDFHMKJ_01345 3.8e-125 1.3.5.4 C FAD binding domain
APDFHMKJ_01346 1.7e-213 1.3.5.4 C FAD binding domain
APDFHMKJ_01347 3.3e-237 L COG2963 Transposase and inactivated derivatives
APDFHMKJ_01348 4.7e-46 pspC KT PspC domain
APDFHMKJ_01350 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
APDFHMKJ_01351 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APDFHMKJ_01352 6.7e-98 M ErfK YbiS YcfS YnhG
APDFHMKJ_01353 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
APDFHMKJ_01354 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
APDFHMKJ_01355 3.1e-240 oppA E ABC transporter substrate-binding protein
APDFHMKJ_01356 2.1e-308 oppA E ABC transporter substrate-binding protein
APDFHMKJ_01357 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APDFHMKJ_01358 0.0 smc D Required for chromosome condensation and partitioning
APDFHMKJ_01359 1.8e-160 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APDFHMKJ_01360 2.5e-288 pipD E Dipeptidase
APDFHMKJ_01362 3.4e-23
APDFHMKJ_01363 4.1e-133 cysA V ABC transporter, ATP-binding protein
APDFHMKJ_01364 0.0 V FtsX-like permease family
APDFHMKJ_01365 2.7e-258 yfnA E amino acid
APDFHMKJ_01366 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APDFHMKJ_01367 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APDFHMKJ_01368 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
APDFHMKJ_01369 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APDFHMKJ_01370 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
APDFHMKJ_01371 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APDFHMKJ_01372 4.6e-213 S SLAP domain
APDFHMKJ_01373 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
APDFHMKJ_01374 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
APDFHMKJ_01375 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APDFHMKJ_01376 3e-38 ynzC S UPF0291 protein
APDFHMKJ_01377 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
APDFHMKJ_01378 0.0 mdlA V ABC transporter
APDFHMKJ_01379 0.0 mdlB V ABC transporter
APDFHMKJ_01380 0.0 pepO 3.4.24.71 O Peptidase family M13
APDFHMKJ_01381 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
APDFHMKJ_01382 2.9e-116 plsC 2.3.1.51 I Acyltransferase
APDFHMKJ_01383 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
APDFHMKJ_01384 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
APDFHMKJ_01385 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APDFHMKJ_01386 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
APDFHMKJ_01387 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APDFHMKJ_01388 1.3e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APDFHMKJ_01389 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
APDFHMKJ_01390 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
APDFHMKJ_01391 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APDFHMKJ_01392 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APDFHMKJ_01393 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
APDFHMKJ_01394 1.4e-196 nusA K Participates in both transcription termination and antitermination
APDFHMKJ_01395 8.8e-47 ylxR K Protein of unknown function (DUF448)
APDFHMKJ_01396 3.2e-47 rplGA J ribosomal protein
APDFHMKJ_01397 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APDFHMKJ_01398 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APDFHMKJ_01399 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APDFHMKJ_01400 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
APDFHMKJ_01401 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APDFHMKJ_01402 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APDFHMKJ_01403 0.0 dnaK O Heat shock 70 kDa protein
APDFHMKJ_01404 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APDFHMKJ_01405 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APDFHMKJ_01406 1.5e-102 srtA 3.4.22.70 M sortase family
APDFHMKJ_01407 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
APDFHMKJ_01408 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
APDFHMKJ_01409 3.4e-79
APDFHMKJ_01410 1e-242 cpdA S Calcineurin-like phosphoesterase
APDFHMKJ_01411 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
APDFHMKJ_01412 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APDFHMKJ_01413 1e-107 ypsA S Belongs to the UPF0398 family
APDFHMKJ_01414 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APDFHMKJ_01415 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
APDFHMKJ_01416 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APDFHMKJ_01417 1.3e-114 dnaD L DnaD domain protein
APDFHMKJ_01418 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
APDFHMKJ_01419 9.2e-89 ypmB S Protein conserved in bacteria
APDFHMKJ_01420 3e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
APDFHMKJ_01421 9.2e-14
APDFHMKJ_01422 2.1e-173 M Glycosyl hydrolases family 25
APDFHMKJ_01423 5e-29
APDFHMKJ_01424 7.9e-19
APDFHMKJ_01426 1.1e-07
APDFHMKJ_01427 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
APDFHMKJ_01428 7.1e-38
APDFHMKJ_01430 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APDFHMKJ_01431 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
APDFHMKJ_01432 1.4e-36 S Cytochrome B5
APDFHMKJ_01433 6e-168 arbZ I Phosphate acyltransferases
APDFHMKJ_01434 1.6e-182 arbY M Glycosyl transferase family 8
APDFHMKJ_01435 5e-184 arbY M Glycosyl transferase family 8
APDFHMKJ_01436 1.5e-155 arbx M Glycosyl transferase family 8
APDFHMKJ_01437 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
APDFHMKJ_01439 4.9e-34
APDFHMKJ_01441 4.8e-131 K response regulator
APDFHMKJ_01442 2.2e-305 vicK 2.7.13.3 T Histidine kinase
APDFHMKJ_01443 1.6e-257 yycH S YycH protein
APDFHMKJ_01444 3.4e-149 yycI S YycH protein
APDFHMKJ_01445 4.1e-147 vicX 3.1.26.11 S domain protein
APDFHMKJ_01446 1.6e-161 htrA 3.4.21.107 O serine protease
APDFHMKJ_01447 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APDFHMKJ_01448 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
APDFHMKJ_01449 5.1e-226 N Uncharacterized conserved protein (DUF2075)
APDFHMKJ_01450 4.8e-205 pbpX1 V Beta-lactamase
APDFHMKJ_01451 0.0 L Helicase C-terminal domain protein
APDFHMKJ_01452 1.3e-273 E amino acid
APDFHMKJ_01453 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
APDFHMKJ_01456 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APDFHMKJ_01457 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APDFHMKJ_01458 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
APDFHMKJ_01459 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
APDFHMKJ_01460 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APDFHMKJ_01461 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
APDFHMKJ_01462 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
APDFHMKJ_01463 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APDFHMKJ_01464 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APDFHMKJ_01465 2.9e-107 IQ reductase
APDFHMKJ_01466 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
APDFHMKJ_01467 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APDFHMKJ_01468 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APDFHMKJ_01469 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APDFHMKJ_01470 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
APDFHMKJ_01471 1.6e-73 marR K Transcriptional regulator, MarR family
APDFHMKJ_01473 3e-53 cvpA S Colicin V production protein
APDFHMKJ_01475 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APDFHMKJ_01476 6e-151 3.1.3.48 T Tyrosine phosphatase family
APDFHMKJ_01477 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
APDFHMKJ_01478 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
APDFHMKJ_01479 2.4e-110 K WHG domain
APDFHMKJ_01480 3e-37
APDFHMKJ_01481 2.4e-10 L Psort location Cytoplasmic, score
APDFHMKJ_01482 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
APDFHMKJ_01483 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APDFHMKJ_01484 4.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
APDFHMKJ_01485 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
APDFHMKJ_01486 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APDFHMKJ_01487 2.2e-120 lsa S ABC transporter
APDFHMKJ_01488 4.5e-168 L COG3385 FOG Transposase and inactivated derivatives
APDFHMKJ_01489 1.6e-105 tag 3.2.2.20 L glycosylase
APDFHMKJ_01490 3.9e-84
APDFHMKJ_01491 1.3e-270 S Calcineurin-like phosphoesterase
APDFHMKJ_01492 0.0 asnB 6.3.5.4 E Asparagine synthase
APDFHMKJ_01493 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
APDFHMKJ_01494 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
APDFHMKJ_01495 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APDFHMKJ_01496 1.3e-102 S Iron-sulfur cluster assembly protein
APDFHMKJ_01497 1.5e-230 XK27_04775 S PAS domain
APDFHMKJ_01498 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APDFHMKJ_01499 1.1e-243 yfnA E Amino Acid
APDFHMKJ_01500 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
APDFHMKJ_01501 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
APDFHMKJ_01502 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
APDFHMKJ_01503 2.6e-280 thrC 4.2.3.1 E Threonine synthase
APDFHMKJ_01504 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
APDFHMKJ_01505 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APDFHMKJ_01506 9.4e-118
APDFHMKJ_01507 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APDFHMKJ_01509 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APDFHMKJ_01510 1.3e-116 S Peptidase family M23
APDFHMKJ_01511 1.5e-102 GM NmrA-like family
APDFHMKJ_01512 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APDFHMKJ_01513 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APDFHMKJ_01514 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APDFHMKJ_01515 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APDFHMKJ_01516 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
APDFHMKJ_01517 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APDFHMKJ_01518 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APDFHMKJ_01519 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
APDFHMKJ_01520 3.7e-250 lctP C L-lactate permease
APDFHMKJ_01521 3.1e-148 glcU U sugar transport
APDFHMKJ_01522 7.1e-46
APDFHMKJ_01523 2.9e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
APDFHMKJ_01524 1.4e-52 EGP Sugar (and other) transporter
APDFHMKJ_01525 1e-104
APDFHMKJ_01526 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
APDFHMKJ_01527 0.0 copA 3.6.3.54 P P-type ATPase
APDFHMKJ_01528 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
APDFHMKJ_01529 4.9e-58 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
APDFHMKJ_01530 2.4e-36
APDFHMKJ_01533 4.4e-103 K Putative DNA-binding domain
APDFHMKJ_01534 9.3e-35
APDFHMKJ_01535 2e-157 S reductase
APDFHMKJ_01536 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
APDFHMKJ_01537 5.6e-08 M Host cell surface-exposed lipoprotein
APDFHMKJ_01538 2.4e-07 S Pfam:DUF955
APDFHMKJ_01539 8.8e-22 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_01540 1.4e-17 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_01541 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
APDFHMKJ_01542 2.5e-47 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
APDFHMKJ_01543 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
APDFHMKJ_01544 9.7e-52 S Iron-sulfur cluster assembly protein
APDFHMKJ_01545 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
APDFHMKJ_01546 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
APDFHMKJ_01547 5.3e-26
APDFHMKJ_01548 8.5e-41 ptsH G phosphocarrier protein HPR
APDFHMKJ_01549 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APDFHMKJ_01550 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APDFHMKJ_01551 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
APDFHMKJ_01552 3.3e-132 coiA 3.6.4.12 S Competence protein
APDFHMKJ_01553 4e-13 coiA 3.6.4.12 S Competence protein
APDFHMKJ_01554 4.6e-114 yjbH Q Thioredoxin
APDFHMKJ_01555 6.8e-110 yjbK S CYTH
APDFHMKJ_01556 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
APDFHMKJ_01557 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APDFHMKJ_01558 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APDFHMKJ_01559 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
APDFHMKJ_01560 4.2e-92 S SNARE associated Golgi protein
APDFHMKJ_01561 4.3e-48 U TraM recognition site of TraD and TraG
APDFHMKJ_01565 1e-30 M domain protein
APDFHMKJ_01566 7.2e-15 S SLAP domain
APDFHMKJ_01567 7.4e-40 M domain protein
APDFHMKJ_01569 1.4e-24 srtA 3.4.22.70 M sortase family
APDFHMKJ_01570 2.3e-21 S SLAP domain
APDFHMKJ_01575 5.7e-11 S Single-strand binding protein family
APDFHMKJ_01586 1.7e-25 S Domain of unknown function (DUF771)
APDFHMKJ_01587 2e-32 K Helix-turn-helix domain
APDFHMKJ_01588 5.7e-16 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_01589 3.4e-29 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_01590 5e-08 S Pfam:DUF955
APDFHMKJ_01591 6.4e-111 L Belongs to the 'phage' integrase family
APDFHMKJ_01593 1.6e-131 I Carboxylesterase family
APDFHMKJ_01594 1.2e-177 mbl D Cell shape determining protein MreB Mrl
APDFHMKJ_01595 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
APDFHMKJ_01596 3.3e-33 S Protein of unknown function (DUF2969)
APDFHMKJ_01597 4.7e-216 rodA D Belongs to the SEDS family
APDFHMKJ_01598 1.8e-78 usp6 T universal stress protein
APDFHMKJ_01599 8.4e-39
APDFHMKJ_01600 2.2e-238 rarA L recombination factor protein RarA
APDFHMKJ_01601 1.3e-84 yueI S Protein of unknown function (DUF1694)
APDFHMKJ_01602 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APDFHMKJ_01603 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APDFHMKJ_01604 1.4e-212 iscS2 2.8.1.7 E Aminotransferase class V
APDFHMKJ_01605 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APDFHMKJ_01606 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
APDFHMKJ_01607 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APDFHMKJ_01608 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APDFHMKJ_01609 3.5e-62 2.4.1.83 GT2 S GtrA-like protein
APDFHMKJ_01610 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
APDFHMKJ_01611 1.5e-94 S Protein of unknown function (DUF3990)
APDFHMKJ_01612 6.5e-44
APDFHMKJ_01614 0.0 3.6.3.8 P P-type ATPase
APDFHMKJ_01615 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
APDFHMKJ_01616 2.5e-52
APDFHMKJ_01617 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APDFHMKJ_01618 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APDFHMKJ_01619 5.7e-126 S Haloacid dehalogenase-like hydrolase
APDFHMKJ_01620 2.3e-108 radC L DNA repair protein
APDFHMKJ_01621 2.4e-176 mreB D cell shape determining protein MreB
APDFHMKJ_01622 2e-147 mreC M Involved in formation and maintenance of cell shape
APDFHMKJ_01623 2.7e-94 mreD
APDFHMKJ_01625 6.4e-54 S Protein of unknown function (DUF3397)
APDFHMKJ_01626 6.3e-78 mraZ K Belongs to the MraZ family
APDFHMKJ_01627 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APDFHMKJ_01628 1.8e-54 ftsL D Cell division protein FtsL
APDFHMKJ_01629 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
APDFHMKJ_01630 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APDFHMKJ_01631 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APDFHMKJ_01632 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APDFHMKJ_01633 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APDFHMKJ_01634 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APDFHMKJ_01635 3.8e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APDFHMKJ_01636 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APDFHMKJ_01637 1.7e-45 yggT S YGGT family
APDFHMKJ_01638 5.7e-149 ylmH S S4 domain protein
APDFHMKJ_01639 2.8e-74 gpsB D DivIVA domain protein
APDFHMKJ_01640 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APDFHMKJ_01641 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
APDFHMKJ_01642 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
APDFHMKJ_01643 6.7e-37
APDFHMKJ_01644 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APDFHMKJ_01645 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
APDFHMKJ_01646 5.4e-56 XK27_04120 S Putative amino acid metabolism
APDFHMKJ_01647 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APDFHMKJ_01648 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
APDFHMKJ_01649 8.3e-106 S Repeat protein
APDFHMKJ_01650 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APDFHMKJ_01651 1.6e-294 L Nuclease-related domain
APDFHMKJ_01652 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
APDFHMKJ_01653 2.3e-43 ybhL S Belongs to the BI1 family
APDFHMKJ_01655 1.2e-210 S Bacterial protein of unknown function (DUF871)
APDFHMKJ_01656 5.5e-36
APDFHMKJ_01657 1.7e-160 scrR K Periplasmic binding protein domain
APDFHMKJ_01658 1.5e-141 msmE G Bacterial extracellular solute-binding protein
APDFHMKJ_01659 8.8e-29
APDFHMKJ_01662 1.1e-110 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_01663 2.5e-75 K Helix-turn-helix domain
APDFHMKJ_01664 1.5e-25 S CAAX protease self-immunity
APDFHMKJ_01665 1.4e-22 S CAAX protease self-immunity
APDFHMKJ_01666 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
APDFHMKJ_01668 2e-44 ybaT E Amino acid permease
APDFHMKJ_01669 1.5e-42 ybaT E Amino acid permease
APDFHMKJ_01670 1.7e-07 S LPXTG cell wall anchor motif
APDFHMKJ_01671 2.6e-146 S Putative ABC-transporter type IV
APDFHMKJ_01672 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APDFHMKJ_01673 1e-295 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APDFHMKJ_01674 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APDFHMKJ_01675 1.2e-232 oppA E ABC transporter substrate-binding protein
APDFHMKJ_01676 8.6e-97 oppA E ABC transporter substrate-binding protein
APDFHMKJ_01677 1.4e-176 K AI-2E family transporter
APDFHMKJ_01678 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
APDFHMKJ_01679 4.1e-18
APDFHMKJ_01680 5.2e-248 G Major Facilitator
APDFHMKJ_01681 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
APDFHMKJ_01682 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
APDFHMKJ_01683 4.9e-174 ABC-SBP S ABC transporter
APDFHMKJ_01684 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
APDFHMKJ_01685 2e-155 P CorA-like Mg2+ transporter protein
APDFHMKJ_01686 3.5e-160 yvgN C Aldo keto reductase
APDFHMKJ_01687 0.0 tetP J elongation factor G
APDFHMKJ_01688 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
APDFHMKJ_01689 1.2e-134 EGP Major facilitator Superfamily
APDFHMKJ_01691 2.2e-142 S Belongs to the UPF0246 family
APDFHMKJ_01692 4.1e-141 aroD S Alpha/beta hydrolase family
APDFHMKJ_01693 2.1e-255 S Archaea bacterial proteins of unknown function
APDFHMKJ_01694 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
APDFHMKJ_01695 1.7e-212 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
APDFHMKJ_01696 1.8e-40 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
APDFHMKJ_01697 1e-24
APDFHMKJ_01698 9.5e-26
APDFHMKJ_01699 2.5e-33
APDFHMKJ_01700 1.4e-53 S Enterocin A Immunity
APDFHMKJ_01701 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
APDFHMKJ_01702 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APDFHMKJ_01703 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
APDFHMKJ_01704 9.6e-121 K response regulator
APDFHMKJ_01706 0.0 V ABC transporter
APDFHMKJ_01707 4.2e-144 V ABC transporter, ATP-binding protein
APDFHMKJ_01708 1.2e-145 V ABC transporter, ATP-binding protein
APDFHMKJ_01709 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
APDFHMKJ_01710 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APDFHMKJ_01711 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
APDFHMKJ_01712 1.5e-153 spo0J K Belongs to the ParB family
APDFHMKJ_01713 3.4e-138 soj D Sporulation initiation inhibitor
APDFHMKJ_01714 5e-148 noc K Belongs to the ParB family
APDFHMKJ_01715 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
APDFHMKJ_01716 0.0 XK27_08315 M Sulfatase
APDFHMKJ_01717 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APDFHMKJ_01718 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
APDFHMKJ_01719 1.4e-98 G Aldose 1-epimerase
APDFHMKJ_01720 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APDFHMKJ_01721 2.1e-116
APDFHMKJ_01722 2.1e-130
APDFHMKJ_01723 7.8e-161 S Oxidoreductase family, NAD-binding Rossmann fold
APDFHMKJ_01724 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APDFHMKJ_01725 1.9e-113 yjbQ P TrkA C-terminal domain protein
APDFHMKJ_01726 8.8e-177 yjbQ P TrkA C-terminal domain protein
APDFHMKJ_01727 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
APDFHMKJ_01728 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APDFHMKJ_01730 1.2e-103 S SLAP domain
APDFHMKJ_01731 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APDFHMKJ_01732 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APDFHMKJ_01733 1.1e-25
APDFHMKJ_01734 1.2e-77 K DNA-templated transcription, initiation
APDFHMKJ_01735 5.3e-41
APDFHMKJ_01737 4.7e-132 S SLAP domain
APDFHMKJ_01738 4.3e-40 S Protein of unknown function (DUF2922)
APDFHMKJ_01739 5.5e-30
APDFHMKJ_01741 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
APDFHMKJ_01742 1.7e-129 manY G PTS system
APDFHMKJ_01743 1e-173 manN G system, mannose fructose sorbose family IID component
APDFHMKJ_01744 1.1e-62 manO S Domain of unknown function (DUF956)
APDFHMKJ_01745 3.3e-158 K Transcriptional regulator
APDFHMKJ_01746 1.3e-85 maa S transferase hexapeptide repeat
APDFHMKJ_01747 6.8e-243 cycA E Amino acid permease
APDFHMKJ_01748 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
APDFHMKJ_01749 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
APDFHMKJ_01750 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APDFHMKJ_01751 0.0 mtlR K Mga helix-turn-helix domain
APDFHMKJ_01752 9.3e-147 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
APDFHMKJ_01753 9.3e-86
APDFHMKJ_01754 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APDFHMKJ_01755 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
APDFHMKJ_01756 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APDFHMKJ_01757 4.4e-140 ypuA S Protein of unknown function (DUF1002)
APDFHMKJ_01758 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
APDFHMKJ_01759 7.3e-126 S Alpha/beta hydrolase family
APDFHMKJ_01762 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
APDFHMKJ_01765 9.4e-33 M Peptidase family M23
APDFHMKJ_01766 2.4e-159 trsE S COG0433 Predicted ATPase
APDFHMKJ_01767 8.4e-15
APDFHMKJ_01769 2.3e-32 I mechanosensitive ion channel activity
APDFHMKJ_01770 8.1e-87 U TraM recognition site of TraD and TraG
APDFHMKJ_01771 5.7e-18
APDFHMKJ_01772 1.5e-239 G Bacterial extracellular solute-binding protein
APDFHMKJ_01773 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
APDFHMKJ_01774 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
APDFHMKJ_01776 0.0 S SLAP domain
APDFHMKJ_01777 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
APDFHMKJ_01778 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
APDFHMKJ_01779 3.4e-42 S RloB-like protein
APDFHMKJ_01780 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
APDFHMKJ_01781 5.7e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
APDFHMKJ_01783 1.7e-12 GT2,GT4 M family 8
APDFHMKJ_01784 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APDFHMKJ_01785 4.1e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APDFHMKJ_01786 3.9e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
APDFHMKJ_01787 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
APDFHMKJ_01788 9e-26
APDFHMKJ_01789 6.4e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APDFHMKJ_01790 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APDFHMKJ_01791 8.7e-84 2.4.1.58 GT8 M family 8
APDFHMKJ_01792 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APDFHMKJ_01793 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APDFHMKJ_01794 1.1e-34 S Protein of unknown function (DUF2508)
APDFHMKJ_01795 5.6e-183 K Transcriptional regulator
APDFHMKJ_01796 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
APDFHMKJ_01797 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APDFHMKJ_01798 4e-57 K Helix-turn-helix domain
APDFHMKJ_01799 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
APDFHMKJ_01800 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
APDFHMKJ_01801 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
APDFHMKJ_01802 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
APDFHMKJ_01803 1.2e-161 phnD P Phosphonate ABC transporter
APDFHMKJ_01805 8.8e-84 uspA T universal stress protein
APDFHMKJ_01806 1.2e-222 patA 2.6.1.1 E Aminotransferase
APDFHMKJ_01807 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
APDFHMKJ_01808 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
APDFHMKJ_01809 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APDFHMKJ_01810 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APDFHMKJ_01811 8.5e-60
APDFHMKJ_01812 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
APDFHMKJ_01813 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APDFHMKJ_01814 5.9e-37 M domain protein
APDFHMKJ_01815 6.4e-148 yxeH S hydrolase
APDFHMKJ_01816 2.7e-32 S reductase
APDFHMKJ_01817 4.4e-39 S reductase
APDFHMKJ_01818 4.8e-34 S reductase
APDFHMKJ_01819 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APDFHMKJ_01820 5.6e-36
APDFHMKJ_01821 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APDFHMKJ_01822 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
APDFHMKJ_01823 2.8e-135
APDFHMKJ_01824 1.3e-258 glnPH2 P ABC transporter permease
APDFHMKJ_01825 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APDFHMKJ_01826 6.4e-224 S Cysteine-rich secretory protein family
APDFHMKJ_01827 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
APDFHMKJ_01828 1.4e-112
APDFHMKJ_01829 2.2e-202 yibE S overlaps another CDS with the same product name
APDFHMKJ_01830 4.9e-129 yibF S overlaps another CDS with the same product name
APDFHMKJ_01831 8.7e-145 I alpha/beta hydrolase fold
APDFHMKJ_01832 0.0 G Belongs to the glycosyl hydrolase 31 family
APDFHMKJ_01833 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
APDFHMKJ_01834 5.4e-13
APDFHMKJ_01835 3e-246 brnQ U Component of the transport system for branched-chain amino acids
APDFHMKJ_01836 2.8e-119 3.6.1.55 F NUDIX domain
APDFHMKJ_01837 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
APDFHMKJ_01838 2.7e-83 S Protein of unknown function (DUF1211)
APDFHMKJ_01839 3.8e-115 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
APDFHMKJ_01840 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
APDFHMKJ_01841 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
APDFHMKJ_01842 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
APDFHMKJ_01843 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
APDFHMKJ_01844 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APDFHMKJ_01845 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APDFHMKJ_01846 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APDFHMKJ_01847 8.1e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
APDFHMKJ_01848 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APDFHMKJ_01849 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APDFHMKJ_01850 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APDFHMKJ_01851 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
APDFHMKJ_01852 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APDFHMKJ_01853 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
APDFHMKJ_01854 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APDFHMKJ_01855 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APDFHMKJ_01856 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APDFHMKJ_01857 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APDFHMKJ_01858 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APDFHMKJ_01859 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APDFHMKJ_01860 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
APDFHMKJ_01861 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APDFHMKJ_01862 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APDFHMKJ_01863 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APDFHMKJ_01864 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APDFHMKJ_01865 6.8e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APDFHMKJ_01866 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APDFHMKJ_01867 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APDFHMKJ_01868 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APDFHMKJ_01869 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APDFHMKJ_01870 2.3e-24 rpmD J Ribosomal protein L30
APDFHMKJ_01871 2.6e-71 rplO J Binds to the 23S rRNA
APDFHMKJ_01872 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APDFHMKJ_01873 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APDFHMKJ_01874 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APDFHMKJ_01875 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
APDFHMKJ_01876 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APDFHMKJ_01877 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APDFHMKJ_01878 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APDFHMKJ_01879 1.4e-60 rplQ J Ribosomal protein L17
APDFHMKJ_01880 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APDFHMKJ_01881 1e-156 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APDFHMKJ_01882 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APDFHMKJ_01883 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APDFHMKJ_01884 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APDFHMKJ_01885 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
APDFHMKJ_01886 8.9e-133 L Phage integrase family
APDFHMKJ_01887 5.8e-78 M LysM domain protein
APDFHMKJ_01888 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APDFHMKJ_01889 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APDFHMKJ_01890 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APDFHMKJ_01891 6.2e-12
APDFHMKJ_01892 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
APDFHMKJ_01893 2.3e-30
APDFHMKJ_01895 2.9e-69 S Iron-sulphur cluster biosynthesis
APDFHMKJ_01896 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
APDFHMKJ_01897 6.2e-59 psiE S Phosphate-starvation-inducible E
APDFHMKJ_01899 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
APDFHMKJ_01900 4.3e-228 amtB P ammonium transporter
APDFHMKJ_01901 1.4e-60
APDFHMKJ_01902 0.0 lhr L DEAD DEAH box helicase
APDFHMKJ_01903 1.4e-245 P P-loop Domain of unknown function (DUF2791)
APDFHMKJ_01904 2.6e-138 S TerB-C domain
APDFHMKJ_01905 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)