ORF_ID e_value Gene_name EC_number CAZy COGs Description
CIEKLHFE_00001 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
CIEKLHFE_00002 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIEKLHFE_00003 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIEKLHFE_00004 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
CIEKLHFE_00005 1.4e-115 mmuP E amino acid
CIEKLHFE_00006 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
CIEKLHFE_00007 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
CIEKLHFE_00008 1.7e-284 E Amino acid permease
CIEKLHFE_00009 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
CIEKLHFE_00010 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
CIEKLHFE_00011 0.0 fhaB M Rib/alpha-like repeat
CIEKLHFE_00012 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
CIEKLHFE_00013 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
CIEKLHFE_00014 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
CIEKLHFE_00015 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
CIEKLHFE_00016 6.8e-209 msmX P Belongs to the ABC transporter superfamily
CIEKLHFE_00017 1.3e-213 malE G Bacterial extracellular solute-binding protein
CIEKLHFE_00018 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
CIEKLHFE_00019 3.3e-147 malG P ABC transporter permease
CIEKLHFE_00020 4.3e-67 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00023 4.8e-28
CIEKLHFE_00024 8e-12 relB L RelB antitoxin
CIEKLHFE_00025 3.2e-15 relB L RelB antitoxin
CIEKLHFE_00026 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
CIEKLHFE_00027 6.5e-82 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
CIEKLHFE_00028 6.2e-143 V N-6 DNA Methylase
CIEKLHFE_00029 2.4e-44
CIEKLHFE_00030 1.3e-284 lsa S ABC transporter
CIEKLHFE_00031 9e-82 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
CIEKLHFE_00032 1.2e-134 S Phage portal protein
CIEKLHFE_00034 7.3e-280 S Phage Terminase
CIEKLHFE_00037 1.9e-56 S Phage terminase, small subunit
CIEKLHFE_00038 1.5e-42 S HNH endonuclease
CIEKLHFE_00039 7.7e-18
CIEKLHFE_00042 1.7e-41 S VRR-NUC domain
CIEKLHFE_00047 2.3e-275 S Phage plasmid primase, P4
CIEKLHFE_00048 6e-41 S Protein of unknown function (DUF669)
CIEKLHFE_00050 5.4e-152 res L Helicase C-terminal domain protein
CIEKLHFE_00052 3.2e-71 S AAA domain
CIEKLHFE_00058 6.1e-13
CIEKLHFE_00059 1.4e-16
CIEKLHFE_00062 1.6e-27
CIEKLHFE_00063 3.7e-47 K ORF6N domain
CIEKLHFE_00064 9.9e-51 K ORF6N domain
CIEKLHFE_00065 1.2e-16 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00066 9e-19 K Cro/C1-type HTH DNA-binding domain
CIEKLHFE_00067 1.6e-19 S Pfam:Peptidase_M78
CIEKLHFE_00068 1.9e-23 S Hypothetical protein (DUF2513)
CIEKLHFE_00071 8.2e-136 sip L Belongs to the 'phage' integrase family
CIEKLHFE_00072 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CIEKLHFE_00073 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
CIEKLHFE_00074 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CIEKLHFE_00075 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CIEKLHFE_00076 2.2e-292 I Acyltransferase
CIEKLHFE_00077 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIEKLHFE_00078 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CIEKLHFE_00079 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
CIEKLHFE_00080 1.1e-243 yfnA E Amino Acid
CIEKLHFE_00081 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIEKLHFE_00082 1.3e-148 yxeH S hydrolase
CIEKLHFE_00083 2.7e-32 S reductase
CIEKLHFE_00084 4.4e-39 S reductase
CIEKLHFE_00085 4.8e-34 S reductase
CIEKLHFE_00086 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CIEKLHFE_00087 3.6e-39 C FMN_bind
CIEKLHFE_00088 1.2e-80
CIEKLHFE_00089 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
CIEKLHFE_00090 2e-85 alkD L DNA alkylation repair enzyme
CIEKLHFE_00091 9.9e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CIEKLHFE_00092 6.4e-128 K UTRA domain
CIEKLHFE_00093 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
CIEKLHFE_00094 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
CIEKLHFE_00095 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
CIEKLHFE_00096 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIEKLHFE_00097 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CIEKLHFE_00098 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIEKLHFE_00099 1.3e-148
CIEKLHFE_00100 6.4e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIEKLHFE_00101 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIEKLHFE_00102 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
CIEKLHFE_00103 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
CIEKLHFE_00104 0.0 comEC S Competence protein ComEC
CIEKLHFE_00105 3.1e-79 comEA L Competence protein ComEA
CIEKLHFE_00106 2.4e-187 ylbL T Belongs to the peptidase S16 family
CIEKLHFE_00107 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CIEKLHFE_00108 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
CIEKLHFE_00109 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
CIEKLHFE_00110 5.9e-211 ftsW D Belongs to the SEDS family
CIEKLHFE_00111 0.0 typA T GTP-binding protein TypA
CIEKLHFE_00112 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIEKLHFE_00113 3.5e-32 ykzG S Belongs to the UPF0356 family
CIEKLHFE_00114 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIEKLHFE_00115 1.7e-301 oppA E ABC transporter, substratebinding protein
CIEKLHFE_00116 1.6e-310 oppA E ABC transporter, substratebinding protein
CIEKLHFE_00117 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIEKLHFE_00118 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIEKLHFE_00119 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CIEKLHFE_00120 2.7e-199 oppD P Belongs to the ABC transporter superfamily
CIEKLHFE_00121 1.9e-175 oppF P Belongs to the ABC transporter superfamily
CIEKLHFE_00122 1.4e-256 pepC 3.4.22.40 E aminopeptidase
CIEKLHFE_00123 3.9e-72 hsp O Belongs to the small heat shock protein (HSP20) family
CIEKLHFE_00124 1.3e-28 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIEKLHFE_00125 9.3e-86
CIEKLHFE_00126 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIEKLHFE_00127 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
CIEKLHFE_00128 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIEKLHFE_00129 4.4e-140 ypuA S Protein of unknown function (DUF1002)
CIEKLHFE_00130 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
CIEKLHFE_00131 7.3e-126 S Alpha/beta hydrolase family
CIEKLHFE_00132 4e-08
CIEKLHFE_00133 6.6e-56
CIEKLHFE_00134 2.7e-57
CIEKLHFE_00135 1.6e-11
CIEKLHFE_00136 8.1e-126 S PAS domain
CIEKLHFE_00137 5.3e-130 gmuR K UTRA
CIEKLHFE_00138 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CIEKLHFE_00139 3.5e-70 S Domain of unknown function (DUF3284)
CIEKLHFE_00140 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIEKLHFE_00141 4e-98 rihB 3.2.2.1 F Nucleoside
CIEKLHFE_00142 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CIEKLHFE_00143 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CIEKLHFE_00144 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIEKLHFE_00145 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CIEKLHFE_00146 9.2e-201 tnpB L Putative transposase DNA-binding domain
CIEKLHFE_00147 4.2e-84 yqeG S HAD phosphatase, family IIIA
CIEKLHFE_00148 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
CIEKLHFE_00149 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIEKLHFE_00150 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
CIEKLHFE_00151 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CIEKLHFE_00152 1.7e-215 ylbM S Belongs to the UPF0348 family
CIEKLHFE_00153 4.7e-97 yceD S Uncharacterized ACR, COG1399
CIEKLHFE_00154 1.2e-126 K response regulator
CIEKLHFE_00155 1.3e-277 arlS 2.7.13.3 T Histidine kinase
CIEKLHFE_00156 0.0 XK27_08315 M Sulfatase
CIEKLHFE_00157 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CIEKLHFE_00158 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CIEKLHFE_00159 1.4e-98 G Aldose 1-epimerase
CIEKLHFE_00160 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIEKLHFE_00161 2.1e-116
CIEKLHFE_00162 2.1e-130
CIEKLHFE_00163 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
CIEKLHFE_00164 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CIEKLHFE_00165 0.0 yjbQ P TrkA C-terminal domain protein
CIEKLHFE_00166 6.5e-180 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
CIEKLHFE_00167 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIEKLHFE_00169 1.8e-131 S SLAP domain
CIEKLHFE_00170 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIEKLHFE_00171 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CIEKLHFE_00172 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CIEKLHFE_00173 2.8e-188 cggR K Putative sugar-binding domain
CIEKLHFE_00175 2.8e-290
CIEKLHFE_00176 4.6e-274 ycaM E amino acid
CIEKLHFE_00177 3.1e-139 S Cysteine-rich secretory protein family
CIEKLHFE_00178 4.2e-77 K MerR HTH family regulatory protein
CIEKLHFE_00179 1.4e-262 lmrB EGP Major facilitator Superfamily
CIEKLHFE_00180 3.1e-48 S Domain of unknown function (DUF4811)
CIEKLHFE_00181 8.8e-29
CIEKLHFE_00184 4.9e-111 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00185 2.5e-75 K Helix-turn-helix domain
CIEKLHFE_00186 1.5e-25 S CAAX protease self-immunity
CIEKLHFE_00187 1.4e-22 S CAAX protease self-immunity
CIEKLHFE_00188 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00190 1.6e-96 ybaT E Amino acid permease
CIEKLHFE_00191 1.7e-07 S LPXTG cell wall anchor motif
CIEKLHFE_00192 4.4e-146 S Putative ABC-transporter type IV
CIEKLHFE_00193 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CIEKLHFE_00194 1.1e-292 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CIEKLHFE_00195 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CIEKLHFE_00196 1.2e-232 oppA E ABC transporter substrate-binding protein
CIEKLHFE_00197 2.1e-95 oppA E ABC transporter substrate-binding protein
CIEKLHFE_00198 3.2e-176 K AI-2E family transporter
CIEKLHFE_00199 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
CIEKLHFE_00200 4.1e-18
CIEKLHFE_00201 4.1e-245 G Major Facilitator
CIEKLHFE_00202 1.3e-79 E Zn peptidase
CIEKLHFE_00203 1e-41 ps115 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00204 5.6e-45
CIEKLHFE_00205 4.5e-66 S Bacteriocin helveticin-J
CIEKLHFE_00206 1.7e-66 S SLAP domain
CIEKLHFE_00207 5.8e-45
CIEKLHFE_00208 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
CIEKLHFE_00209 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
CIEKLHFE_00210 1.7e-174 ABC-SBP S ABC transporter
CIEKLHFE_00211 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CIEKLHFE_00212 1.6e-48 P CorA-like Mg2+ transporter protein
CIEKLHFE_00213 5.2e-75 P CorA-like Mg2+ transporter protein
CIEKLHFE_00214 3.5e-160 yvgN C Aldo keto reductase
CIEKLHFE_00215 0.0 tetP J elongation factor G
CIEKLHFE_00216 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
CIEKLHFE_00217 1.2e-134 EGP Major facilitator Superfamily
CIEKLHFE_00219 4.7e-211 yttB EGP Major facilitator Superfamily
CIEKLHFE_00220 1.5e-230 XK27_04775 S PAS domain
CIEKLHFE_00221 4.5e-103 S Iron-sulfur cluster assembly protein
CIEKLHFE_00222 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CIEKLHFE_00223 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CIEKLHFE_00224 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
CIEKLHFE_00225 0.0 asnB 6.3.5.4 E Asparagine synthase
CIEKLHFE_00226 1.7e-273 S Calcineurin-like phosphoesterase
CIEKLHFE_00227 3.9e-84
CIEKLHFE_00228 1.6e-105 tag 3.2.2.20 L glycosylase
CIEKLHFE_00229 4.1e-172 L COG3385 FOG Transposase and inactivated derivatives
CIEKLHFE_00230 1.5e-102 srtA 3.4.22.70 M sortase family
CIEKLHFE_00231 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CIEKLHFE_00232 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CIEKLHFE_00233 0.0 dnaK O Heat shock 70 kDa protein
CIEKLHFE_00234 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIEKLHFE_00235 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CIEKLHFE_00236 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CIEKLHFE_00237 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIEKLHFE_00238 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIEKLHFE_00239 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIEKLHFE_00240 3.2e-47 rplGA J ribosomal protein
CIEKLHFE_00241 8.8e-47 ylxR K Protein of unknown function (DUF448)
CIEKLHFE_00242 1.4e-196 nusA K Participates in both transcription termination and antitermination
CIEKLHFE_00243 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
CIEKLHFE_00244 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIEKLHFE_00245 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CIEKLHFE_00246 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CIEKLHFE_00247 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
CIEKLHFE_00248 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIEKLHFE_00249 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CIEKLHFE_00250 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CIEKLHFE_00251 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIEKLHFE_00252 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
CIEKLHFE_00253 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
CIEKLHFE_00254 2.9e-116 plsC 2.3.1.51 I Acyltransferase
CIEKLHFE_00255 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CIEKLHFE_00256 0.0 pepO 3.4.24.71 O Peptidase family M13
CIEKLHFE_00257 0.0 mdlB V ABC transporter
CIEKLHFE_00258 0.0 mdlA V ABC transporter
CIEKLHFE_00259 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
CIEKLHFE_00260 3e-38 ynzC S UPF0291 protein
CIEKLHFE_00261 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CIEKLHFE_00262 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
CIEKLHFE_00263 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
CIEKLHFE_00264 4.6e-213 S SLAP domain
CIEKLHFE_00265 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CIEKLHFE_00266 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CIEKLHFE_00267 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIEKLHFE_00268 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CIEKLHFE_00269 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIEKLHFE_00270 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CIEKLHFE_00271 2.7e-258 yfnA E amino acid
CIEKLHFE_00272 3.2e-10 S Domain of unknown function DUF87
CIEKLHFE_00273 1.2e-63 S SIR2-like domain
CIEKLHFE_00274 8.3e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
CIEKLHFE_00275 2.3e-51 3.1.21.3 V Type I restriction modification DNA specificity domain
CIEKLHFE_00276 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
CIEKLHFE_00277 3.4e-42 S RloB-like protein
CIEKLHFE_00278 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
CIEKLHFE_00279 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
CIEKLHFE_00280 0.0 S SLAP domain
CIEKLHFE_00282 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
CIEKLHFE_00283 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
CIEKLHFE_00284 1.5e-239 G Bacterial extracellular solute-binding protein
CIEKLHFE_00285 5.7e-18
CIEKLHFE_00286 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
CIEKLHFE_00287 1.2e-100 treR K UTRA
CIEKLHFE_00288 4.5e-111 treB G phosphotransferase system
CIEKLHFE_00289 6.8e-153 treB G phosphotransferase system
CIEKLHFE_00290 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CIEKLHFE_00291 2.5e-191 yrvN L AAA C-terminal domain
CIEKLHFE_00292 3e-37
CIEKLHFE_00293 2.4e-110 K WHG domain
CIEKLHFE_00294 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
CIEKLHFE_00295 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
CIEKLHFE_00296 6e-151 3.1.3.48 T Tyrosine phosphatase family
CIEKLHFE_00297 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CIEKLHFE_00298 3e-53 cvpA S Colicin V production protein
CIEKLHFE_00299 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
CIEKLHFE_00300 1.5e-147 noc K Belongs to the ParB family
CIEKLHFE_00301 3.4e-138 soj D Sporulation initiation inhibitor
CIEKLHFE_00302 8.5e-154 spo0J K Belongs to the ParB family
CIEKLHFE_00303 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
CIEKLHFE_00304 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CIEKLHFE_00305 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
CIEKLHFE_00306 1.2e-145 V ABC transporter, ATP-binding protein
CIEKLHFE_00307 4.2e-144 V ABC transporter, ATP-binding protein
CIEKLHFE_00308 0.0 V ABC transporter
CIEKLHFE_00310 9.6e-121 K response regulator
CIEKLHFE_00311 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
CIEKLHFE_00312 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIEKLHFE_00313 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CIEKLHFE_00314 1.4e-53 S Enterocin A Immunity
CIEKLHFE_00315 2.5e-33
CIEKLHFE_00316 9.5e-26
CIEKLHFE_00317 1e-24
CIEKLHFE_00318 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
CIEKLHFE_00319 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
CIEKLHFE_00320 2.1e-255 S Archaea bacterial proteins of unknown function
CIEKLHFE_00321 1.2e-16
CIEKLHFE_00322 2.3e-43 ybhL S Belongs to the BI1 family
CIEKLHFE_00323 1.2e-210 S Bacterial protein of unknown function (DUF871)
CIEKLHFE_00324 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CIEKLHFE_00325 5.2e-114
CIEKLHFE_00326 1.8e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIEKLHFE_00327 2.5e-286 clcA P chloride
CIEKLHFE_00328 3.6e-33 E Zn peptidase
CIEKLHFE_00329 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00330 1.2e-44
CIEKLHFE_00331 1.1e-106 S Bacteriocin helveticin-J
CIEKLHFE_00332 1.3e-117 S SLAP domain
CIEKLHFE_00333 3.5e-136 S SLAP domain
CIEKLHFE_00334 2.8e-210
CIEKLHFE_00335 1.2e-18
CIEKLHFE_00336 7e-248 EGP Sugar (and other) transporter
CIEKLHFE_00337 1.2e-105
CIEKLHFE_00338 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
CIEKLHFE_00339 0.0 copA 3.6.3.54 P P-type ATPase
CIEKLHFE_00340 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CIEKLHFE_00341 9.2e-57 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CIEKLHFE_00342 2.4e-36
CIEKLHFE_00345 1.8e-31
CIEKLHFE_00346 4.6e-138
CIEKLHFE_00347 2.6e-151 V ABC transporter transmembrane region
CIEKLHFE_00348 1.4e-37 S Putative adhesin
CIEKLHFE_00349 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
CIEKLHFE_00350 6.6e-61 psiE S Phosphate-starvation-inducible E
CIEKLHFE_00352 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CIEKLHFE_00353 4.3e-228 amtB P ammonium transporter
CIEKLHFE_00354 1.4e-60
CIEKLHFE_00355 0.0 lhr L DEAD DEAH box helicase
CIEKLHFE_00356 1.4e-245 P P-loop Domain of unknown function (DUF2791)
CIEKLHFE_00357 2.6e-138 S TerB-C domain
CIEKLHFE_00358 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
CIEKLHFE_00359 1e-79 S AAA domain
CIEKLHFE_00360 3.3e-61 3.6.1.55 F NUDIX domain
CIEKLHFE_00361 2.9e-69 S Iron-sulphur cluster biosynthesis
CIEKLHFE_00363 2.3e-30
CIEKLHFE_00364 2.6e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
CIEKLHFE_00365 6.2e-12
CIEKLHFE_00366 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIEKLHFE_00367 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIEKLHFE_00368 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIEKLHFE_00369 5.8e-78 M LysM domain protein
CIEKLHFE_00370 4.7e-159 D nuclear chromosome segregation
CIEKLHFE_00371 1.2e-105 G Phosphoglycerate mutase family
CIEKLHFE_00372 2.6e-89 G Histidine phosphatase superfamily (branch 1)
CIEKLHFE_00373 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
CIEKLHFE_00374 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CIEKLHFE_00376 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
CIEKLHFE_00378 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
CIEKLHFE_00379 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
CIEKLHFE_00380 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
CIEKLHFE_00381 4.4e-144 K SIS domain
CIEKLHFE_00382 4.8e-44 slpX S SLAP domain
CIEKLHFE_00383 5.3e-167 slpX S SLAP domain
CIEKLHFE_00384 1.3e-22 3.6.4.12 S transposase or invertase
CIEKLHFE_00385 6.6e-11
CIEKLHFE_00386 3.2e-240 npr 1.11.1.1 C NADH oxidase
CIEKLHFE_00389 4.4e-239 oppA2 E ABC transporter, substratebinding protein
CIEKLHFE_00390 3.4e-45 oppA2 E ABC transporter, substratebinding protein
CIEKLHFE_00391 3.3e-179
CIEKLHFE_00392 1.3e-125 gntR1 K UTRA
CIEKLHFE_00393 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
CIEKLHFE_00394 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CIEKLHFE_00395 1.7e-204 csaB M Glycosyl transferases group 1
CIEKLHFE_00396 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIEKLHFE_00397 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CIEKLHFE_00398 1.4e-204 tnpB L Putative transposase DNA-binding domain
CIEKLHFE_00399 0.0 pacL 3.6.3.8 P P-type ATPase
CIEKLHFE_00400 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CIEKLHFE_00401 6e-258 epsU S Polysaccharide biosynthesis protein
CIEKLHFE_00402 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
CIEKLHFE_00403 2.6e-82 ydcK S Belongs to the SprT family
CIEKLHFE_00405 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
CIEKLHFE_00406 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CIEKLHFE_00407 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIEKLHFE_00408 5.8e-203 camS S sex pheromone
CIEKLHFE_00409 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIEKLHFE_00410 6.4e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CIEKLHFE_00411 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIEKLHFE_00412 2.7e-171 yegS 2.7.1.107 G Lipid kinase
CIEKLHFE_00413 4.3e-108 ybhL S Belongs to the BI1 family
CIEKLHFE_00414 2.6e-57
CIEKLHFE_00415 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
CIEKLHFE_00416 2.8e-244 nhaC C Na H antiporter NhaC
CIEKLHFE_00417 6.3e-201 pbpX V Beta-lactamase
CIEKLHFE_00418 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIEKLHFE_00419 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
CIEKLHFE_00424 1.9e-259 emrY EGP Major facilitator Superfamily
CIEKLHFE_00425 2e-91 yxdD K Bacterial regulatory proteins, tetR family
CIEKLHFE_00426 0.0 4.2.1.53 S Myosin-crossreactive antigen
CIEKLHFE_00427 5.5e-148 S cog cog1373
CIEKLHFE_00428 5.1e-248 E Amino acid permease
CIEKLHFE_00429 5.2e-20 E Amino acid permease
CIEKLHFE_00430 5.8e-100 L Helix-turn-helix domain
CIEKLHFE_00431 1.3e-160 L hmm pf00665
CIEKLHFE_00433 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIEKLHFE_00434 3.5e-101 ylbE GM NAD(P)H-binding
CIEKLHFE_00435 7.6e-94 S VanZ like family
CIEKLHFE_00436 8.9e-133 yebC K Transcriptional regulatory protein
CIEKLHFE_00437 1.7e-179 comGA NU Type II IV secretion system protein
CIEKLHFE_00438 1.7e-171 comGB NU type II secretion system
CIEKLHFE_00439 3.1e-43 comGC U competence protein ComGC
CIEKLHFE_00440 1.8e-69
CIEKLHFE_00441 2.3e-41
CIEKLHFE_00442 3.8e-77 comGF U Putative Competence protein ComGF
CIEKLHFE_00443 1.6e-21
CIEKLHFE_00444 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
CIEKLHFE_00445 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIEKLHFE_00447 3.8e-72 L Belongs to the 'phage' integrase family
CIEKLHFE_00448 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
CIEKLHFE_00449 2.8e-77 P Cobalt transport protein
CIEKLHFE_00450 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
CIEKLHFE_00451 6.5e-91 G Peptidase_C39 like family
CIEKLHFE_00452 2.8e-162 M NlpC/P60 family
CIEKLHFE_00453 8.4e-25 G Peptidase_C39 like family
CIEKLHFE_00455 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CIEKLHFE_00456 7.5e-103 G Phosphoglycerate mutase family
CIEKLHFE_00458 5.2e-104
CIEKLHFE_00459 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CIEKLHFE_00460 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CIEKLHFE_00461 5.2e-119 T Transcriptional regulatory protein, C terminal
CIEKLHFE_00462 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
CIEKLHFE_00463 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIEKLHFE_00464 1.2e-152 pstA P Phosphate transport system permease protein PstA
CIEKLHFE_00465 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
CIEKLHFE_00466 4.2e-145 pstS P Phosphate
CIEKLHFE_00467 1.3e-30
CIEKLHFE_00468 6.3e-192 oppA E ABC transporter, substratebinding protein
CIEKLHFE_00469 4.7e-275 ytgP S Polysaccharide biosynthesis protein
CIEKLHFE_00470 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIEKLHFE_00471 1.1e-121 3.6.1.27 I Acid phosphatase homologues
CIEKLHFE_00472 2.8e-168 K LysR substrate binding domain
CIEKLHFE_00473 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CIEKLHFE_00474 6.2e-43 1.3.5.4 C FAD binding domain
CIEKLHFE_00475 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
CIEKLHFE_00476 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
CIEKLHFE_00477 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CIEKLHFE_00478 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CIEKLHFE_00479 6e-268 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CIEKLHFE_00480 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CIEKLHFE_00481 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
CIEKLHFE_00482 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
CIEKLHFE_00483 3.7e-130 ybbH_2 K rpiR family
CIEKLHFE_00484 3.4e-195 S Bacterial protein of unknown function (DUF871)
CIEKLHFE_00485 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
CIEKLHFE_00486 1.8e-119 S Putative esterase
CIEKLHFE_00487 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CIEKLHFE_00488 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
CIEKLHFE_00490 8.5e-260 qacA EGP Major facilitator Superfamily
CIEKLHFE_00491 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIEKLHFE_00494 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
CIEKLHFE_00496 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CIEKLHFE_00497 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
CIEKLHFE_00498 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CIEKLHFE_00499 1.9e-261 frdC 1.3.5.4 C FAD binding domain
CIEKLHFE_00500 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CIEKLHFE_00501 3.4e-73 metI P ABC transporter permease
CIEKLHFE_00502 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIEKLHFE_00503 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
CIEKLHFE_00504 2.4e-175 F DNA/RNA non-specific endonuclease
CIEKLHFE_00505 0.0 aha1 P E1-E2 ATPase
CIEKLHFE_00506 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CIEKLHFE_00507 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIEKLHFE_00508 1.2e-250 yifK E Amino acid permease
CIEKLHFE_00509 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
CIEKLHFE_00510 2.5e-215 sptS 2.7.13.3 T Histidine kinase
CIEKLHFE_00511 9.4e-209 EGP Major facilitator Superfamily
CIEKLHFE_00512 5.6e-68 O OsmC-like protein
CIEKLHFE_00513 2.3e-87 S Protein of unknown function (DUF805)
CIEKLHFE_00514 3.2e-77
CIEKLHFE_00515 3.1e-278
CIEKLHFE_00516 5.8e-83 S Fic/DOC family
CIEKLHFE_00517 3.3e-275 yjeM E Amino Acid
CIEKLHFE_00518 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIEKLHFE_00519 0.0 kup P Transport of potassium into the cell
CIEKLHFE_00520 7.3e-74
CIEKLHFE_00521 2.1e-45 S PFAM Archaeal ATPase
CIEKLHFE_00523 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIEKLHFE_00524 5.9e-45
CIEKLHFE_00525 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component
CIEKLHFE_00526 1.6e-135 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CIEKLHFE_00527 3e-145 potD2 P ABC transporter
CIEKLHFE_00528 4.9e-251 ade 3.5.4.2 F Adenine deaminase C-terminal domain
CIEKLHFE_00530 5.8e-73 S domain protein
CIEKLHFE_00531 1.8e-230 steT_1 E amino acid
CIEKLHFE_00532 2.2e-139 puuD S peptidase C26
CIEKLHFE_00534 2.4e-172 V HNH endonuclease
CIEKLHFE_00535 6.4e-135 S PFAM Archaeal ATPase
CIEKLHFE_00536 3.5e-247 yifK E Amino acid permease
CIEKLHFE_00537 9.7e-234 cycA E Amino acid permease
CIEKLHFE_00538 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CIEKLHFE_00539 0.0 clpE O AAA domain (Cdc48 subfamily)
CIEKLHFE_00540 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
CIEKLHFE_00541 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIEKLHFE_00542 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
CIEKLHFE_00543 0.0 XK27_06780 V ABC transporter permease
CIEKLHFE_00544 1.9e-36
CIEKLHFE_00545 7.9e-291 ytgP S Polysaccharide biosynthesis protein
CIEKLHFE_00546 2.7e-137 lysA2 M Glycosyl hydrolases family 25
CIEKLHFE_00547 2.3e-133 S Protein of unknown function (DUF975)
CIEKLHFE_00548 7.6e-177 pbpX2 V Beta-lactamase
CIEKLHFE_00549 6.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CIEKLHFE_00550 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIEKLHFE_00551 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
CIEKLHFE_00552 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIEKLHFE_00553 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
CIEKLHFE_00554 4.1e-44
CIEKLHFE_00555 1e-207 ywhK S Membrane
CIEKLHFE_00556 1.5e-80 ykuL S (CBS) domain
CIEKLHFE_00557 0.0 cadA P P-type ATPase
CIEKLHFE_00558 2.8e-205 napA P Sodium/hydrogen exchanger family
CIEKLHFE_00559 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
CIEKLHFE_00560 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
CIEKLHFE_00561 4.1e-276 V ABC transporter transmembrane region
CIEKLHFE_00562 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00563 5.4e-51
CIEKLHFE_00564 4.2e-154 EGP Major facilitator Superfamily
CIEKLHFE_00565 3e-111 ropB K Transcriptional regulator
CIEKLHFE_00566 2.7e-120 S CAAX protease self-immunity
CIEKLHFE_00567 1.6e-194 S DUF218 domain
CIEKLHFE_00568 0.0 macB_3 V ABC transporter, ATP-binding protein
CIEKLHFE_00569 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CIEKLHFE_00570 2.8e-100 S ECF transporter, substrate-specific component
CIEKLHFE_00571 4.7e-202 tcsA S ABC transporter substrate-binding protein PnrA-like
CIEKLHFE_00572 2.3e-176 tcsA S ABC transporter substrate-binding protein PnrA-like
CIEKLHFE_00573 3.7e-282 xylG 3.6.3.17 S ABC transporter
CIEKLHFE_00574 2.1e-197 yufP S Belongs to the binding-protein-dependent transport system permease family
CIEKLHFE_00575 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
CIEKLHFE_00576 2.4e-158 yeaE S Aldo/keto reductase family
CIEKLHFE_00577 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CIEKLHFE_00578 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CIEKLHFE_00579 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CIEKLHFE_00580 9.4e-72
CIEKLHFE_00581 8.2e-140 cof S haloacid dehalogenase-like hydrolase
CIEKLHFE_00582 8.2e-230 pbuG S permease
CIEKLHFE_00583 2.1e-76 S ABC-2 family transporter protein
CIEKLHFE_00584 4.7e-60 S ABC-2 family transporter protein
CIEKLHFE_00585 2.4e-92 V ABC transporter, ATP-binding protein
CIEKLHFE_00586 7.7e-65 L An automated process has identified a potential problem with this gene model
CIEKLHFE_00587 1.3e-36
CIEKLHFE_00588 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CIEKLHFE_00589 3.7e-146 ykuT M mechanosensitive ion channel
CIEKLHFE_00590 6.9e-100 V ATPases associated with a variety of cellular activities
CIEKLHFE_00591 1.7e-139
CIEKLHFE_00592 5.4e-113
CIEKLHFE_00593 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CIEKLHFE_00594 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
CIEKLHFE_00595 5.6e-179 S PFAM Archaeal ATPase
CIEKLHFE_00596 2.4e-73 S cog cog1373
CIEKLHFE_00602 1.7e-29 S Bacteriophage holin of superfamily 6 (Holin_LLH)
CIEKLHFE_00603 8.8e-84 S N-acetylmuramoyl-L-alanine amidase activity
CIEKLHFE_00605 1.8e-10
CIEKLHFE_00606 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CIEKLHFE_00607 2.3e-23 S Protein of unknown function (DUF2929)
CIEKLHFE_00608 0.0 dnaE 2.7.7.7 L DNA polymerase
CIEKLHFE_00609 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CIEKLHFE_00610 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CIEKLHFE_00611 1e-167 cvfB S S1 domain
CIEKLHFE_00612 2.9e-165 xerD D recombinase XerD
CIEKLHFE_00613 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIEKLHFE_00614 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIEKLHFE_00615 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIEKLHFE_00616 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CIEKLHFE_00617 2.2e-112 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CIEKLHFE_00618 2.7e-18 M Lysin motif
CIEKLHFE_00619 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CIEKLHFE_00620 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
CIEKLHFE_00621 4.3e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CIEKLHFE_00622 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CIEKLHFE_00623 3.9e-229 S Tetratricopeptide repeat protein
CIEKLHFE_00624 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIEKLHFE_00625 5.2e-08
CIEKLHFE_00626 3e-89 ntd 2.4.2.6 F Nucleoside
CIEKLHFE_00627 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CIEKLHFE_00628 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
CIEKLHFE_00629 2.2e-82 uspA T universal stress protein
CIEKLHFE_00631 1.2e-161 phnD P Phosphonate ABC transporter
CIEKLHFE_00632 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CIEKLHFE_00633 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
CIEKLHFE_00634 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
CIEKLHFE_00635 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
CIEKLHFE_00636 2.3e-309 oppA3 E ABC transporter, substratebinding protein
CIEKLHFE_00637 2.4e-60 ypaA S Protein of unknown function (DUF1304)
CIEKLHFE_00638 2.1e-28 S Peptidase propeptide and YPEB domain
CIEKLHFE_00639 8.9e-240 L transposase, IS605 OrfB family
CIEKLHFE_00642 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
CIEKLHFE_00645 1.2e-32 M Peptidase family M23
CIEKLHFE_00646 1.8e-159 trsE S COG0433 Predicted ATPase
CIEKLHFE_00647 2.4e-14
CIEKLHFE_00649 3.9e-32 I mechanosensitive ion channel activity
CIEKLHFE_00650 2.3e-86 U TraM recognition site of TraD and TraG
CIEKLHFE_00651 3.2e-19
CIEKLHFE_00653 3.2e-182 M Glycosyl hydrolases family 25
CIEKLHFE_00654 8e-27
CIEKLHFE_00655 7e-16
CIEKLHFE_00657 1.7e-16
CIEKLHFE_00659 1.2e-10
CIEKLHFE_00664 6.4e-70
CIEKLHFE_00665 3.4e-35
CIEKLHFE_00666 1.4e-09
CIEKLHFE_00667 2.8e-112 Z012_12235 S Baseplate J-like protein
CIEKLHFE_00668 1.9e-47 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
CIEKLHFE_00669 1e-149 D Alpha beta
CIEKLHFE_00670 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CIEKLHFE_00671 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
CIEKLHFE_00672 8.3e-143 licT K CAT RNA binding domain
CIEKLHFE_00673 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CIEKLHFE_00674 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIEKLHFE_00675 1.6e-118
CIEKLHFE_00676 1.8e-75 K Penicillinase repressor
CIEKLHFE_00677 1.4e-147 S hydrolase
CIEKLHFE_00678 1.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIEKLHFE_00679 2e-172 ybbR S YbbR-like protein
CIEKLHFE_00680 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CIEKLHFE_00681 7.3e-208 potD P ABC transporter
CIEKLHFE_00682 4.8e-127 potC P ABC transporter permease
CIEKLHFE_00683 1.3e-129 potB P ABC transporter permease
CIEKLHFE_00684 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CIEKLHFE_00685 2e-163 murB 1.3.1.98 M Cell wall formation
CIEKLHFE_00686 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
CIEKLHFE_00687 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
CIEKLHFE_00688 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CIEKLHFE_00689 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CIEKLHFE_00690 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
CIEKLHFE_00691 1.2e-94
CIEKLHFE_00693 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CIEKLHFE_00694 6.5e-146 epsB M biosynthesis protein
CIEKLHFE_00695 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
CIEKLHFE_00696 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
CIEKLHFE_00697 6.7e-110 rfbP M Bacterial sugar transferase
CIEKLHFE_00698 1.9e-117 cps1D M Domain of unknown function (DUF4422)
CIEKLHFE_00700 7.5e-231 pbuG S permease
CIEKLHFE_00701 2.5e-119 K helix_turn_helix, mercury resistance
CIEKLHFE_00702 3.3e-37
CIEKLHFE_00703 2.7e-83 S Protein of unknown function (DUF1211)
CIEKLHFE_00704 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
CIEKLHFE_00705 2.8e-119 3.6.1.55 F NUDIX domain
CIEKLHFE_00706 3.9e-246 brnQ U Component of the transport system for branched-chain amino acids
CIEKLHFE_00707 0.0 L Plasmid pRiA4b ORF-3-like protein
CIEKLHFE_00708 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
CIEKLHFE_00709 9e-144 2.4.2.3 F Phosphorylase superfamily
CIEKLHFE_00710 1.9e-138 2.4.2.3 F Phosphorylase superfamily
CIEKLHFE_00711 6e-112
CIEKLHFE_00713 1.7e-110 E Belongs to the SOS response-associated peptidase family
CIEKLHFE_00714 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIEKLHFE_00715 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
CIEKLHFE_00716 2e-103 S TPM domain
CIEKLHFE_00717 2.4e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
CIEKLHFE_00718 2.5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
CIEKLHFE_00719 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIEKLHFE_00720 1e-147 tatD L hydrolase, TatD family
CIEKLHFE_00721 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CIEKLHFE_00722 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CIEKLHFE_00723 4.5e-39 veg S Biofilm formation stimulator VEG
CIEKLHFE_00724 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CIEKLHFE_00725 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIEKLHFE_00726 5.3e-80
CIEKLHFE_00727 1.2e-292 S SLAP domain
CIEKLHFE_00728 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIEKLHFE_00729 5.1e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CIEKLHFE_00730 3.7e-184 G Transmembrane secretion effector
CIEKLHFE_00731 6.1e-136 V ABC transporter transmembrane region
CIEKLHFE_00732 2.9e-224 L transposase, IS605 OrfB family
CIEKLHFE_00733 1.1e-75 V ABC transporter transmembrane region
CIEKLHFE_00734 6.5e-64 L RelB antitoxin
CIEKLHFE_00735 2.1e-131 cobQ S glutamine amidotransferase
CIEKLHFE_00736 1.8e-81 M NlpC/P60 family
CIEKLHFE_00739 2.6e-155
CIEKLHFE_00740 7.8e-38
CIEKLHFE_00741 2e-32
CIEKLHFE_00742 6.2e-163 EG EamA-like transporter family
CIEKLHFE_00743 5e-165 EG EamA-like transporter family
CIEKLHFE_00744 1.2e-139 yicL EG EamA-like transporter family
CIEKLHFE_00745 4.3e-107
CIEKLHFE_00746 1.1e-110
CIEKLHFE_00747 5.8e-186 XK27_05540 S DUF218 domain
CIEKLHFE_00748 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
CIEKLHFE_00749 4.7e-85
CIEKLHFE_00750 3.9e-57
CIEKLHFE_00751 4.7e-25 S Protein conserved in bacteria
CIEKLHFE_00752 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
CIEKLHFE_00753 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CIEKLHFE_00754 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CIEKLHFE_00755 1.2e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIEKLHFE_00756 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CIEKLHFE_00757 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
CIEKLHFE_00758 1.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIEKLHFE_00759 4.2e-182 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CIEKLHFE_00760 2.6e-35 yaaA S S4 domain protein YaaA
CIEKLHFE_00761 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIEKLHFE_00762 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIEKLHFE_00763 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIEKLHFE_00764 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
CIEKLHFE_00765 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CIEKLHFE_00766 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CIEKLHFE_00767 1.9e-22 K Putative DNA-binding domain
CIEKLHFE_00768 7.6e-239 pyrP F Permease
CIEKLHFE_00769 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CIEKLHFE_00770 9.2e-262 emrY EGP Major facilitator Superfamily
CIEKLHFE_00771 2.2e-311 ybiT S ABC transporter, ATP-binding protein
CIEKLHFE_00772 5.9e-174 S Aldo keto reductase
CIEKLHFE_00773 2.7e-138
CIEKLHFE_00774 2.8e-202 steT E amino acid
CIEKLHFE_00775 2.4e-26 steT E amino acid
CIEKLHFE_00776 8.6e-243 steT E amino acid
CIEKLHFE_00777 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
CIEKLHFE_00778 1.9e-147 glnH ET ABC transporter
CIEKLHFE_00779 1.4e-80 K Transcriptional regulator, MarR family
CIEKLHFE_00780 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
CIEKLHFE_00781 0.0 V ABC transporter transmembrane region
CIEKLHFE_00782 1.6e-100 S ABC-type cobalt transport system, permease component
CIEKLHFE_00783 1e-246 G MFS/sugar transport protein
CIEKLHFE_00784 9.8e-39 udk 2.7.1.48 F Zeta toxin
CIEKLHFE_00785 3.8e-46 udk 2.7.1.48 F Zeta toxin
CIEKLHFE_00786 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIEKLHFE_00787 1.2e-146 glnH ET ABC transporter substrate-binding protein
CIEKLHFE_00788 3.7e-90 gluC P ABC transporter permease
CIEKLHFE_00789 4.7e-109 glnP P ABC transporter permease
CIEKLHFE_00790 1.1e-164 S Protein of unknown function (DUF2974)
CIEKLHFE_00791 5.6e-86
CIEKLHFE_00792 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
CIEKLHFE_00793 1.3e-235 G Bacterial extracellular solute-binding protein
CIEKLHFE_00794 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
CIEKLHFE_00795 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIEKLHFE_00796 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CIEKLHFE_00797 0.0 kup P Transport of potassium into the cell
CIEKLHFE_00798 9.1e-175 rihB 3.2.2.1 F Nucleoside
CIEKLHFE_00799 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
CIEKLHFE_00800 1.2e-154 S hydrolase
CIEKLHFE_00801 2.5e-59 S Enterocin A Immunity
CIEKLHFE_00802 3.1e-136 glcR K DeoR C terminal sensor domain
CIEKLHFE_00803 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CIEKLHFE_00804 2e-160 rssA S Phospholipase, patatin family
CIEKLHFE_00805 5.4e-147 S hydrolase
CIEKLHFE_00806 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
CIEKLHFE_00807 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
CIEKLHFE_00808 1.6e-80
CIEKLHFE_00809 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CIEKLHFE_00810 2.1e-39
CIEKLHFE_00811 3.9e-119 C nitroreductase
CIEKLHFE_00812 1.7e-249 yhdP S Transporter associated domain
CIEKLHFE_00813 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CIEKLHFE_00814 0.0 1.3.5.4 C FAD binding domain
CIEKLHFE_00815 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CIEKLHFE_00816 4.6e-257 pepC 3.4.22.40 E aminopeptidase
CIEKLHFE_00818 3.4e-53
CIEKLHFE_00819 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CIEKLHFE_00820 8.4e-265 S Fibronectin type III domain
CIEKLHFE_00821 3.6e-140 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
CIEKLHFE_00822 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
CIEKLHFE_00823 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
CIEKLHFE_00824 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
CIEKLHFE_00825 2.1e-47
CIEKLHFE_00827 5e-07 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00828 7.2e-10
CIEKLHFE_00833 1.1e-90 S AntA/AntB antirepressor
CIEKLHFE_00835 2e-20 cro K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00836 2.8e-13 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00838 3e-59
CIEKLHFE_00839 6e-14
CIEKLHFE_00843 2.5e-13
CIEKLHFE_00844 1.6e-147 sip L Belongs to the 'phage' integrase family
CIEKLHFE_00845 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CIEKLHFE_00846 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CIEKLHFE_00847 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CIEKLHFE_00848 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
CIEKLHFE_00849 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CIEKLHFE_00850 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CIEKLHFE_00851 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CIEKLHFE_00852 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
CIEKLHFE_00853 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
CIEKLHFE_00854 9.7e-169
CIEKLHFE_00855 7.5e-143
CIEKLHFE_00856 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CIEKLHFE_00857 1.4e-26
CIEKLHFE_00858 6.7e-145
CIEKLHFE_00859 5.1e-137
CIEKLHFE_00860 4.5e-141
CIEKLHFE_00861 9.6e-124 skfE V ATPases associated with a variety of cellular activities
CIEKLHFE_00862 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
CIEKLHFE_00863 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CIEKLHFE_00864 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CIEKLHFE_00865 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
CIEKLHFE_00866 4.8e-81 mutT 3.6.1.55 F NUDIX domain
CIEKLHFE_00867 1.4e-127 S Peptidase family M23
CIEKLHFE_00868 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CIEKLHFE_00869 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CIEKLHFE_00870 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CIEKLHFE_00871 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CIEKLHFE_00872 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
CIEKLHFE_00873 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CIEKLHFE_00874 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CIEKLHFE_00875 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
CIEKLHFE_00876 3.5e-71 yqeY S YqeY-like protein
CIEKLHFE_00877 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CIEKLHFE_00878 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CIEKLHFE_00879 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
CIEKLHFE_00881 4.7e-55 dnaC L IstB-like ATP binding protein
CIEKLHFE_00882 1.7e-34 S Conserved phage C-terminus (Phg_2220_C)
CIEKLHFE_00883 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CIEKLHFE_00884 1.4e-107 M Transport protein ComB
CIEKLHFE_00885 2.2e-129 blpT
CIEKLHFE_00889 3e-21
CIEKLHFE_00890 3.7e-83
CIEKLHFE_00891 8.2e-31 yozG K Transcriptional regulator
CIEKLHFE_00892 2e-23
CIEKLHFE_00893 1.7e-67
CIEKLHFE_00894 1.1e-164 natA S ABC transporter, ATP-binding protein
CIEKLHFE_00895 1.8e-218 natB CP ABC-2 family transporter protein
CIEKLHFE_00896 1.8e-136 fruR K DeoR C terminal sensor domain
CIEKLHFE_00897 8.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CIEKLHFE_00898 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
CIEKLHFE_00899 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
CIEKLHFE_00900 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
CIEKLHFE_00901 1.6e-117 fhuC P ABC transporter
CIEKLHFE_00902 5e-129 znuB U ABC 3 transport family
CIEKLHFE_00903 2e-264 lctP C L-lactate permease
CIEKLHFE_00904 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CIEKLHFE_00905 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
CIEKLHFE_00906 1.2e-11
CIEKLHFE_00907 1.6e-25 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_00909 1.4e-94
CIEKLHFE_00910 2.2e-54 oppA E ABC transporter substrate-binding protein
CIEKLHFE_00911 1.3e-149 oppA E ABC transporter substrate-binding protein
CIEKLHFE_00912 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CIEKLHFE_00913 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
CIEKLHFE_00914 1.4e-36 S Cytochrome B5
CIEKLHFE_00915 6e-168 arbZ I Phosphate acyltransferases
CIEKLHFE_00916 1.6e-182 arbY M Glycosyl transferase family 8
CIEKLHFE_00917 5e-184 arbY M Glycosyl transferase family 8
CIEKLHFE_00918 5e-156 arbx M Glycosyl transferase family 8
CIEKLHFE_00919 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
CIEKLHFE_00921 4.9e-34
CIEKLHFE_00923 4.8e-131 K response regulator
CIEKLHFE_00924 2.2e-305 vicK 2.7.13.3 T Histidine kinase
CIEKLHFE_00925 1.6e-257 yycH S YycH protein
CIEKLHFE_00926 3.4e-149 yycI S YycH protein
CIEKLHFE_00927 4.1e-147 vicX 3.1.26.11 S domain protein
CIEKLHFE_00928 1.6e-161 htrA 3.4.21.107 O serine protease
CIEKLHFE_00929 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CIEKLHFE_00930 5.6e-36
CIEKLHFE_00931 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIEKLHFE_00932 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
CIEKLHFE_00933 2.8e-135
CIEKLHFE_00934 1.3e-258 glnPH2 P ABC transporter permease
CIEKLHFE_00935 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIEKLHFE_00936 6.4e-224 S Cysteine-rich secretory protein family
CIEKLHFE_00937 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CIEKLHFE_00938 1.4e-112
CIEKLHFE_00939 6.3e-202 yibE S overlaps another CDS with the same product name
CIEKLHFE_00940 4.9e-129 yibF S overlaps another CDS with the same product name
CIEKLHFE_00941 2.5e-144 I alpha/beta hydrolase fold
CIEKLHFE_00942 0.0 G Belongs to the glycosyl hydrolase 31 family
CIEKLHFE_00943 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CIEKLHFE_00944 6.9e-47 mdtG EGP Major facilitator Superfamily
CIEKLHFE_00945 1.7e-152 mdtG EGP Major facilitator Superfamily
CIEKLHFE_00946 1.3e-174
CIEKLHFE_00947 2.8e-47 lysM M LysM domain
CIEKLHFE_00948 0.0 pepN 3.4.11.2 E aminopeptidase
CIEKLHFE_00949 1.3e-250 dtpT U amino acid peptide transporter
CIEKLHFE_00950 1.2e-18 S Sugar efflux transporter for intercellular exchange
CIEKLHFE_00951 6.6e-70 XK27_02470 K LytTr DNA-binding domain
CIEKLHFE_00952 2.1e-92 liaI S membrane
CIEKLHFE_00953 4e-16
CIEKLHFE_00954 3.9e-186 S Putative peptidoglycan binding domain
CIEKLHFE_00955 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
CIEKLHFE_00956 9e-121
CIEKLHFE_00957 1.3e-116 S Peptidase family M23
CIEKLHFE_00958 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIEKLHFE_00960 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CIEKLHFE_00961 9.4e-118
CIEKLHFE_00962 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CIEKLHFE_00963 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CIEKLHFE_00964 2.6e-280 thrC 4.2.3.1 E Threonine synthase
CIEKLHFE_00965 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
CIEKLHFE_00966 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
CIEKLHFE_00967 0.0 pepO 3.4.24.71 O Peptidase family M13
CIEKLHFE_00968 1.1e-183 scrR K helix_turn _helix lactose operon repressor
CIEKLHFE_00969 3.7e-295 scrB 3.2.1.26 GH32 G invertase
CIEKLHFE_00970 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
CIEKLHFE_00971 2.3e-181 M CHAP domain
CIEKLHFE_00972 3.5e-75
CIEKLHFE_00973 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIEKLHFE_00974 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CIEKLHFE_00975 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CIEKLHFE_00976 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CIEKLHFE_00977 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CIEKLHFE_00978 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CIEKLHFE_00979 9.6e-41 yajC U Preprotein translocase
CIEKLHFE_00980 1.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CIEKLHFE_00981 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CIEKLHFE_00982 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
CIEKLHFE_00983 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CIEKLHFE_00984 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CIEKLHFE_00985 2e-42 yrzL S Belongs to the UPF0297 family
CIEKLHFE_00986 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIEKLHFE_00987 1.1e-50 yrzB S Belongs to the UPF0473 family
CIEKLHFE_00988 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CIEKLHFE_00989 3.5e-54 trxA O Belongs to the thioredoxin family
CIEKLHFE_00990 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CIEKLHFE_00991 1.1e-71 yslB S Protein of unknown function (DUF2507)
CIEKLHFE_00992 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CIEKLHFE_00993 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CIEKLHFE_00994 7.7e-30 ropB K Helix-turn-helix domain
CIEKLHFE_00996 5.3e-41
CIEKLHFE_00997 1.4e-76 K DNA-templated transcription, initiation
CIEKLHFE_00998 1.1e-25
CIEKLHFE_00999 2.1e-144 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CIEKLHFE_01001 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CIEKLHFE_01002 3e-102 S SLAP domain
CIEKLHFE_01003 4.3e-40 S Protein of unknown function (DUF2922)
CIEKLHFE_01004 5.5e-30
CIEKLHFE_01006 3.5e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CIEKLHFE_01007 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
CIEKLHFE_01008 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
CIEKLHFE_01009 4.2e-172 2.7.1.2 GK ROK family
CIEKLHFE_01010 5.6e-43
CIEKLHFE_01011 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
CIEKLHFE_01012 6.9e-69 S Domain of unknown function (DUF1934)
CIEKLHFE_01013 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CIEKLHFE_01014 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CIEKLHFE_01015 4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIEKLHFE_01016 1e-77 K acetyltransferase
CIEKLHFE_01017 1.4e-283 pipD E Dipeptidase
CIEKLHFE_01018 3.7e-156 msmR K AraC-like ligand binding domain
CIEKLHFE_01019 1.5e-223 pbuX F xanthine permease
CIEKLHFE_01020 7.7e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CIEKLHFE_01021 9.3e-30 K Helix-turn-helix
CIEKLHFE_01022 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CIEKLHFE_01023 1.2e-60 L Putative transposase DNA-binding domain
CIEKLHFE_01025 1.9e-98 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIEKLHFE_01026 2.4e-10 L Psort location Cytoplasmic, score
CIEKLHFE_01027 9e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CIEKLHFE_01028 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CIEKLHFE_01029 3.8e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CIEKLHFE_01030 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
CIEKLHFE_01031 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CIEKLHFE_01032 2.2e-120 lsa S ABC transporter
CIEKLHFE_01033 5.3e-26
CIEKLHFE_01034 8.5e-41 ptsH G phosphocarrier protein HPR
CIEKLHFE_01035 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIEKLHFE_01036 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CIEKLHFE_01037 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CIEKLHFE_01038 1.4e-158 coiA 3.6.4.12 S Competence protein
CIEKLHFE_01039 4.6e-114 yjbH Q Thioredoxin
CIEKLHFE_01040 6.8e-110 yjbK S CYTH
CIEKLHFE_01041 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
CIEKLHFE_01042 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIEKLHFE_01043 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CIEKLHFE_01044 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
CIEKLHFE_01045 4.2e-92 S SNARE associated Golgi protein
CIEKLHFE_01046 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CIEKLHFE_01047 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
CIEKLHFE_01048 2.6e-214 yubA S AI-2E family transporter
CIEKLHFE_01049 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CIEKLHFE_01050 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
CIEKLHFE_01051 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CIEKLHFE_01052 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
CIEKLHFE_01053 1.9e-236 S Peptidase M16
CIEKLHFE_01054 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
CIEKLHFE_01055 5.2e-97 ymfM S Helix-turn-helix domain
CIEKLHFE_01056 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIEKLHFE_01057 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIEKLHFE_01058 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
CIEKLHFE_01059 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
CIEKLHFE_01060 5.1e-119 yvyE 3.4.13.9 S YigZ family
CIEKLHFE_01061 4.7e-246 comFA L Helicase C-terminal domain protein
CIEKLHFE_01062 9.4e-132 comFC S Competence protein
CIEKLHFE_01063 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIEKLHFE_01064 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CIEKLHFE_01065 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIEKLHFE_01066 5.1e-17
CIEKLHFE_01067 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CIEKLHFE_01068 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIEKLHFE_01069 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CIEKLHFE_01070 1.5e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CIEKLHFE_01071 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CIEKLHFE_01072 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CIEKLHFE_01073 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CIEKLHFE_01074 4.1e-90 S Short repeat of unknown function (DUF308)
CIEKLHFE_01075 6.2e-165 rapZ S Displays ATPase and GTPase activities
CIEKLHFE_01076 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CIEKLHFE_01077 2.1e-171 whiA K May be required for sporulation
CIEKLHFE_01078 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CIEKLHFE_01079 0.0 S SH3-like domain
CIEKLHFE_01080 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
CIEKLHFE_01081 9e-98
CIEKLHFE_01082 5.9e-106 K LysR substrate binding domain
CIEKLHFE_01083 1e-20
CIEKLHFE_01084 2.3e-215 S Sterol carrier protein domain
CIEKLHFE_01085 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CIEKLHFE_01086 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
CIEKLHFE_01087 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIEKLHFE_01088 5.7e-233 arcA 3.5.3.6 E Arginine
CIEKLHFE_01089 9e-137 lysR5 K LysR substrate binding domain
CIEKLHFE_01090 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
CIEKLHFE_01091 1e-48 S Metal binding domain of Ada
CIEKLHFE_01092 1.8e-87 M hydrolase, family 25
CIEKLHFE_01093 7.6e-39 S Bacteriophage holin of superfamily 6 (Holin_LLH)
CIEKLHFE_01098 9.3e-35
CIEKLHFE_01099 2e-157 S reductase
CIEKLHFE_01100 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
CIEKLHFE_01101 8.9e-67 L Belongs to the 'phage' integrase family
CIEKLHFE_01102 2.6e-09 S Pfam:DUF955
CIEKLHFE_01103 1.1e-17 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_01104 2.6e-21 2.3.1.19 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_01105 9.8e-26 K Helix-turn-helix domain
CIEKLHFE_01107 4.1e-09 S Arc-like DNA binding domain
CIEKLHFE_01109 4e-21 K Conserved phage C-terminus (Phg_2220_C)
CIEKLHFE_01110 1.5e-26 S Domain of unknown function (DUF771)
CIEKLHFE_01118 1.6e-10
CIEKLHFE_01119 3.3e-11 S Single-strand binding protein family
CIEKLHFE_01125 2.4e-21 S SLAP domain
CIEKLHFE_01126 1.4e-24 srtA 3.4.22.70 M sortase family
CIEKLHFE_01128 6e-42 M domain protein
CIEKLHFE_01129 6.8e-15 S SLAP domain
CIEKLHFE_01130 7.9e-31 M domain protein
CIEKLHFE_01134 6.3e-47 U TraM recognition site of TraD and TraG
CIEKLHFE_01135 3.7e-93 sip L Belongs to the 'phage' integrase family
CIEKLHFE_01136 6.2e-12
CIEKLHFE_01137 1.2e-54 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIEKLHFE_01138 4.7e-15 S Pfam:Peptidase_M78
CIEKLHFE_01139 3.7e-18 ps115 K sequence-specific DNA binding
CIEKLHFE_01140 3.1e-12
CIEKLHFE_01141 3.7e-13
CIEKLHFE_01143 1.4e-85 S AntA/AntB antirepressor
CIEKLHFE_01149 1.8e-31 S Helix-turn-helix domain
CIEKLHFE_01150 5.5e-18
CIEKLHFE_01152 4.6e-45
CIEKLHFE_01153 6.1e-128 S Protein of unknown function (DUF1351)
CIEKLHFE_01154 5.3e-131 S ERF superfamily
CIEKLHFE_01155 1.2e-100 L Helix-turn-helix domain
CIEKLHFE_01163 3.8e-219 XK27_11280 S Psort location CytoplasmicMembrane, score
CIEKLHFE_01166 3.3e-09 arpU S Phage transcriptional regulator, ArpU family
CIEKLHFE_01169 3e-19 ps333 L Terminase small subunit
CIEKLHFE_01170 1.1e-201 S Terminase-like family
CIEKLHFE_01171 6.2e-135 S Protein of unknown function (DUF1073)
CIEKLHFE_01172 1.3e-47 S Phage Mu protein F like protein
CIEKLHFE_01173 5e-12 S Lysin motif
CIEKLHFE_01174 1.6e-57 S Uncharacterized protein conserved in bacteria (DUF2213)
CIEKLHFE_01175 4.1e-34
CIEKLHFE_01176 2.4e-93 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
CIEKLHFE_01177 1.6e-19 S Protein of unknown function (DUF4054)
CIEKLHFE_01178 1.1e-28
CIEKLHFE_01179 1.6e-25
CIEKLHFE_01180 3.3e-31
CIEKLHFE_01181 3.5e-103 Z012_02110 S Protein of unknown function (DUF3383)
CIEKLHFE_01182 9.3e-29
CIEKLHFE_01183 2.9e-09
CIEKLHFE_01185 1e-220 3.4.14.13 M Phage tail tape measure protein TP901
CIEKLHFE_01186 3.8e-59 M LysM domain
CIEKLHFE_01187 2.7e-46
CIEKLHFE_01188 5.5e-87 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
CIEKLHFE_01189 3.4e-134 S Phage portal protein
CIEKLHFE_01191 2.8e-210 S Phage Terminase
CIEKLHFE_01192 9e-47 S HicB_like antitoxin of bacterial toxin-antitoxin system
CIEKLHFE_01193 3.4e-18 N HicA toxin of bacterial toxin-antitoxin,
CIEKLHFE_01194 1.6e-55 L Phage terminase, small subunit
CIEKLHFE_01195 3.5e-49 L HNH nucleases
CIEKLHFE_01197 3.1e-14 arpU S Phage transcriptional regulator, ArpU family
CIEKLHFE_01198 9.8e-12
CIEKLHFE_01200 3.3e-37 S VRR_NUC
CIEKLHFE_01211 2.7e-268 S Phage plasmid primase, P4
CIEKLHFE_01212 1.7e-30 S Protein of unknown function (DUF669)
CIEKLHFE_01213 4.7e-148 res L Helicase C-terminal domain protein
CIEKLHFE_01215 1.6e-70 S AAA domain
CIEKLHFE_01221 3.5e-46
CIEKLHFE_01222 4.4e-79 S Phage antirepressor protein KilAC domain
CIEKLHFE_01223 4.7e-18 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_01225 2.2e-15 E Pfam:DUF955
CIEKLHFE_01227 9.9e-118 L Belongs to the 'phage' integrase family
CIEKLHFE_01228 1.4e-30
CIEKLHFE_01229 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
CIEKLHFE_01230 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CIEKLHFE_01231 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CIEKLHFE_01232 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CIEKLHFE_01233 1.1e-138 stp 3.1.3.16 T phosphatase
CIEKLHFE_01234 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CIEKLHFE_01235 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIEKLHFE_01236 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CIEKLHFE_01237 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CIEKLHFE_01238 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
CIEKLHFE_01239 1.1e-77 6.3.3.2 S ASCH
CIEKLHFE_01240 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
CIEKLHFE_01241 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CIEKLHFE_01242 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CIEKLHFE_01243 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIEKLHFE_01244 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIEKLHFE_01245 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CIEKLHFE_01246 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIEKLHFE_01247 3.4e-71 yqhY S Asp23 family, cell envelope-related function
CIEKLHFE_01248 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CIEKLHFE_01249 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CIEKLHFE_01250 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CIEKLHFE_01251 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CIEKLHFE_01252 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CIEKLHFE_01253 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
CIEKLHFE_01255 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CIEKLHFE_01256 4.3e-298 S Predicted membrane protein (DUF2207)
CIEKLHFE_01257 1.2e-155 cinI S Serine hydrolase (FSH1)
CIEKLHFE_01258 1e-205 M Glycosyl hydrolases family 25
CIEKLHFE_01260 8.5e-178 I Carboxylesterase family
CIEKLHFE_01261 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
CIEKLHFE_01262 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
CIEKLHFE_01263 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
CIEKLHFE_01264 1.3e-122 S haloacid dehalogenase-like hydrolase
CIEKLHFE_01267 5.7e-171 M Glycosyl hydrolases family 25
CIEKLHFE_01268 5e-29
CIEKLHFE_01269 2.2e-113 S SLAP domain
CIEKLHFE_01270 2.6e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
CIEKLHFE_01271 5.7e-46 S An automated process has identified a potential problem with this gene model
CIEKLHFE_01272 3e-137 S Protein of unknown function (DUF3100)
CIEKLHFE_01273 4e-245 3.5.1.47 S Peptidase dimerisation domain
CIEKLHFE_01274 5.8e-230 Q Imidazolonepropionase and related amidohydrolases
CIEKLHFE_01275 0.0 oppA E ABC transporter
CIEKLHFE_01276 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
CIEKLHFE_01277 0.0 mco Q Multicopper oxidase
CIEKLHFE_01278 1.9e-25
CIEKLHFE_01279 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
CIEKLHFE_01280 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
CIEKLHFE_01281 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIEKLHFE_01282 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIEKLHFE_01283 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CIEKLHFE_01284 2.2e-142 S Belongs to the UPF0246 family
CIEKLHFE_01285 4.1e-141 aroD S Alpha/beta hydrolase family
CIEKLHFE_01286 3.5e-111 G phosphoglycerate mutase
CIEKLHFE_01287 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
CIEKLHFE_01288 3.3e-176 hrtB V ABC transporter permease
CIEKLHFE_01289 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
CIEKLHFE_01290 1.3e-273 pipD E Dipeptidase
CIEKLHFE_01291 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
CIEKLHFE_01292 6.2e-288 P ABC transporter
CIEKLHFE_01293 4.3e-36
CIEKLHFE_01295 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
CIEKLHFE_01296 2.5e-86 K GNAT family
CIEKLHFE_01297 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
CIEKLHFE_01298 2.9e-122 rbtT P Major Facilitator Superfamily
CIEKLHFE_01299 4.2e-63 lmrB EGP Major facilitator Superfamily
CIEKLHFE_01300 7.8e-39 yjeM E Amino Acid
CIEKLHFE_01301 3.4e-175 yjeM E Amino Acid
CIEKLHFE_01302 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CIEKLHFE_01303 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
CIEKLHFE_01304 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CIEKLHFE_01305 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CIEKLHFE_01306 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CIEKLHFE_01307 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIEKLHFE_01308 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CIEKLHFE_01309 2.7e-216 aspC 2.6.1.1 E Aminotransferase
CIEKLHFE_01310 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIEKLHFE_01311 2.1e-194 pbpX1 V Beta-lactamase
CIEKLHFE_01312 1.2e-299 I Protein of unknown function (DUF2974)
CIEKLHFE_01313 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
CIEKLHFE_01314 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
CIEKLHFE_01315 3.6e-241 3.6.3.6 P Cation transporter/ATPase, N-terminus
CIEKLHFE_01316 1.9e-19
CIEKLHFE_01317 3.9e-51 V ABC-type multidrug transport system, ATPase and permease components
CIEKLHFE_01318 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
CIEKLHFE_01319 0.0 L PLD-like domain
CIEKLHFE_01320 4.8e-42 S SnoaL-like domain
CIEKLHFE_01321 5.4e-53 hipB K sequence-specific DNA binding
CIEKLHFE_01322 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
CIEKLHFE_01323 3.4e-27
CIEKLHFE_01325 6.4e-54 S Protein of unknown function (DUF3397)
CIEKLHFE_01326 6.3e-78 mraZ K Belongs to the MraZ family
CIEKLHFE_01327 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CIEKLHFE_01328 1.8e-54 ftsL D Cell division protein FtsL
CIEKLHFE_01329 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CIEKLHFE_01330 3.3e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIEKLHFE_01331 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIEKLHFE_01332 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIEKLHFE_01333 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CIEKLHFE_01334 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CIEKLHFE_01335 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIEKLHFE_01336 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CIEKLHFE_01337 1.7e-45 yggT S YGGT family
CIEKLHFE_01338 5.7e-149 ylmH S S4 domain protein
CIEKLHFE_01339 2.8e-74 gpsB D DivIVA domain protein
CIEKLHFE_01340 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIEKLHFE_01341 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
CIEKLHFE_01342 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
CIEKLHFE_01343 6.7e-37
CIEKLHFE_01344 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIEKLHFE_01345 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
CIEKLHFE_01346 5.4e-56 XK27_04120 S Putative amino acid metabolism
CIEKLHFE_01347 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CIEKLHFE_01348 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
CIEKLHFE_01349 2.4e-105 S Repeat protein
CIEKLHFE_01350 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CIEKLHFE_01351 1.6e-294 L Nuclease-related domain
CIEKLHFE_01352 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CIEKLHFE_01353 1.9e-75 M LysM domain
CIEKLHFE_01354 1.3e-42
CIEKLHFE_01356 4.9e-35
CIEKLHFE_01357 4.5e-76 yniG EGP Major facilitator Superfamily
CIEKLHFE_01358 5.4e-237 L transposase, IS605 OrfB family
CIEKLHFE_01359 1.4e-109 yniG EGP Major facilitator Superfamily
CIEKLHFE_01360 2.4e-128 S cog cog1373
CIEKLHFE_01362 1.7e-257 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
CIEKLHFE_01363 2.6e-208 glf 5.4.99.9 M UDP-galactopyranose mutase
CIEKLHFE_01365 7.3e-197 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CIEKLHFE_01366 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
CIEKLHFE_01367 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CIEKLHFE_01369 8.3e-138 L An automated process has identified a potential problem with this gene model
CIEKLHFE_01370 2.8e-48 S Peptidase propeptide and YPEB domain
CIEKLHFE_01371 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
CIEKLHFE_01372 7e-87 gtcA S Teichoic acid glycosylation protein
CIEKLHFE_01373 4.1e-80 fld C Flavodoxin
CIEKLHFE_01374 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
CIEKLHFE_01375 3.6e-163 yihY S Belongs to the UPF0761 family
CIEKLHFE_01376 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CIEKLHFE_01377 7.4e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
CIEKLHFE_01378 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
CIEKLHFE_01379 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CIEKLHFE_01380 5.1e-226 N Uncharacterized conserved protein (DUF2075)
CIEKLHFE_01381 4.8e-205 pbpX1 V Beta-lactamase
CIEKLHFE_01382 0.0 L Helicase C-terminal domain protein
CIEKLHFE_01383 1.3e-273 E amino acid
CIEKLHFE_01384 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
CIEKLHFE_01387 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIEKLHFE_01388 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CIEKLHFE_01389 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CIEKLHFE_01390 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
CIEKLHFE_01391 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CIEKLHFE_01392 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
CIEKLHFE_01393 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
CIEKLHFE_01394 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CIEKLHFE_01395 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CIEKLHFE_01396 2.9e-107 IQ reductase
CIEKLHFE_01397 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CIEKLHFE_01398 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIEKLHFE_01399 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIEKLHFE_01400 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIEKLHFE_01401 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CIEKLHFE_01402 1.6e-73 marR K Transcriptional regulator, MarR family
CIEKLHFE_01403 1e-57
CIEKLHFE_01404 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
CIEKLHFE_01405 1e-30 S cog cog1373
CIEKLHFE_01406 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
CIEKLHFE_01407 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
CIEKLHFE_01408 4.3e-75
CIEKLHFE_01409 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIEKLHFE_01410 1.3e-168 dnaI L Primosomal protein DnaI
CIEKLHFE_01411 5.1e-251 dnaB L Replication initiation and membrane attachment
CIEKLHFE_01412 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIEKLHFE_01413 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CIEKLHFE_01414 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CIEKLHFE_01415 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIEKLHFE_01416 3.5e-25 qmcA O prohibitin homologues
CIEKLHFE_01417 7.4e-105 qmcA O prohibitin homologues
CIEKLHFE_01418 8e-51 L RelB antitoxin
CIEKLHFE_01419 4.5e-188 S Bacteriocin helveticin-J
CIEKLHFE_01420 4.4e-283 M Peptidase family M1 domain
CIEKLHFE_01421 1.8e-176 S SLAP domain
CIEKLHFE_01422 6.9e-218 mepA V MATE efflux family protein
CIEKLHFE_01423 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CIEKLHFE_01424 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIEKLHFE_01425 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CIEKLHFE_01427 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CIEKLHFE_01428 6.5e-221 ecsB U ABC transporter
CIEKLHFE_01429 5.7e-135 ecsA V ABC transporter, ATP-binding protein
CIEKLHFE_01430 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
CIEKLHFE_01431 3.9e-25
CIEKLHFE_01432 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CIEKLHFE_01433 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
CIEKLHFE_01434 1.1e-265
CIEKLHFE_01435 2.4e-51 S Domain of unknown function DUF1829
CIEKLHFE_01436 2.9e-23
CIEKLHFE_01437 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
CIEKLHFE_01438 0.0 L AAA domain
CIEKLHFE_01439 1e-226 yhaO L Ser Thr phosphatase family protein
CIEKLHFE_01440 7.2e-56 yheA S Belongs to the UPF0342 family
CIEKLHFE_01441 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CIEKLHFE_01442 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CIEKLHFE_01443 9.4e-46
CIEKLHFE_01444 1.8e-38 D Alpha beta
CIEKLHFE_01445 1.4e-118 D Alpha beta
CIEKLHFE_01446 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIEKLHFE_01447 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
CIEKLHFE_01448 1.6e-85
CIEKLHFE_01449 2.7e-74
CIEKLHFE_01450 1.4e-140 hlyX S Transporter associated domain
CIEKLHFE_01451 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CIEKLHFE_01452 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
CIEKLHFE_01453 0.0 clpE O Belongs to the ClpA ClpB family
CIEKLHFE_01454 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
CIEKLHFE_01455 3.4e-79
CIEKLHFE_01456 1e-242 cpdA S Calcineurin-like phosphoesterase
CIEKLHFE_01457 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CIEKLHFE_01458 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CIEKLHFE_01459 1e-107 ypsA S Belongs to the UPF0398 family
CIEKLHFE_01460 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CIEKLHFE_01461 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
CIEKLHFE_01462 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CIEKLHFE_01463 1.3e-114 dnaD L DnaD domain protein
CIEKLHFE_01464 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
CIEKLHFE_01465 2.4e-89 ypmB S Protein conserved in bacteria
CIEKLHFE_01466 3e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIEKLHFE_01467 9.2e-14
CIEKLHFE_01468 2.1e-173 M Glycosyl hydrolases family 25
CIEKLHFE_01469 1.9e-28
CIEKLHFE_01470 3.1e-240 oppA E ABC transporter substrate-binding protein
CIEKLHFE_01471 2.1e-308 oppA E ABC transporter substrate-binding protein
CIEKLHFE_01472 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CIEKLHFE_01473 0.0 smc D Required for chromosome condensation and partitioning
CIEKLHFE_01474 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CIEKLHFE_01475 2.5e-288 pipD E Dipeptidase
CIEKLHFE_01476 3.4e-23
CIEKLHFE_01477 4.1e-133 cysA V ABC transporter, ATP-binding protein
CIEKLHFE_01478 0.0 V FtsX-like permease family
CIEKLHFE_01479 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CIEKLHFE_01481 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIEKLHFE_01482 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
CIEKLHFE_01483 1.3e-61 M Glycosyl hydrolases family 25
CIEKLHFE_01484 2.6e-61 M Glycosyl hydrolases family 25
CIEKLHFE_01485 1.5e-102 GM NmrA-like family
CIEKLHFE_01486 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIEKLHFE_01487 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CIEKLHFE_01488 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CIEKLHFE_01489 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CIEKLHFE_01490 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CIEKLHFE_01491 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CIEKLHFE_01492 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CIEKLHFE_01493 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CIEKLHFE_01494 3.7e-250 lctP C L-lactate permease
CIEKLHFE_01495 3.1e-148 glcU U sugar transport
CIEKLHFE_01496 7.1e-46
CIEKLHFE_01497 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CIEKLHFE_01498 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CIEKLHFE_01499 3.7e-19 S Alpha beta hydrolase
CIEKLHFE_01500 1.2e-63 S Alpha beta hydrolase
CIEKLHFE_01501 1.9e-37
CIEKLHFE_01502 7e-50
CIEKLHFE_01503 5.1e-12 S haloacid dehalogenase-like hydrolase
CIEKLHFE_01504 1.4e-95 sip L Belongs to the 'phage' integrase family
CIEKLHFE_01507 4.8e-17 S protein disulfide oxidoreductase activity
CIEKLHFE_01508 6.6e-11 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_01511 3.2e-10
CIEKLHFE_01516 2.2e-53 S Protein of unknown function (DUF1351)
CIEKLHFE_01517 1.6e-44 S ERF superfamily
CIEKLHFE_01518 2.7e-31 K Helix-turn-helix domain
CIEKLHFE_01520 1.6e-31 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
CIEKLHFE_01521 4e-65 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
CIEKLHFE_01522 1.5e-21 radC L DNA repair protein
CIEKLHFE_01528 2.7e-33 Q DNA (cytosine-5-)-methyltransferase activity
CIEKLHFE_01533 2.2e-67 S ORF6C domain
CIEKLHFE_01535 5.3e-36 S VRR_NUC
CIEKLHFE_01536 3.4e-09
CIEKLHFE_01542 1.1e-20 S N-methyltransferase activity
CIEKLHFE_01545 9.6e-187 S Terminase-like family
CIEKLHFE_01546 3.3e-91 S Protein of unknown function (DUF1073)
CIEKLHFE_01547 1.3e-55 S Phage Mu protein F like protein
CIEKLHFE_01548 4.8e-20 S Lysin motif
CIEKLHFE_01549 1.3e-53 S Uncharacterized protein conserved in bacteria (DUF2213)
CIEKLHFE_01550 1e-22
CIEKLHFE_01551 2.9e-36 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
CIEKLHFE_01552 1.6e-27 S Protein of unknown function (DUF4054)
CIEKLHFE_01553 7.7e-42
CIEKLHFE_01554 2.7e-10
CIEKLHFE_01555 1.6e-27
CIEKLHFE_01556 1.7e-133 Z012_02110 S Protein of unknown function (DUF3383)
CIEKLHFE_01557 1.3e-11
CIEKLHFE_01558 1.1e-11
CIEKLHFE_01559 2.5e-197 M Phage tail tape measure protein TP901
CIEKLHFE_01560 1.3e-59 M LysM domain
CIEKLHFE_01561 2.7e-46
CIEKLHFE_01562 1.3e-103
CIEKLHFE_01563 2.7e-37
CIEKLHFE_01564 7.4e-29
CIEKLHFE_01565 6.7e-114 Z012_12235 S Baseplate J-like protein
CIEKLHFE_01566 2.9e-09
CIEKLHFE_01567 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
CIEKLHFE_01568 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CIEKLHFE_01569 6.7e-98 M ErfK YbiS YcfS YnhG
CIEKLHFE_01570 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIEKLHFE_01571 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CIEKLHFE_01573 4.7e-46 pspC KT PspC domain
CIEKLHFE_01574 3.3e-237 L COG2963 Transposase and inactivated derivatives
CIEKLHFE_01575 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
CIEKLHFE_01576 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CIEKLHFE_01577 9.6e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CIEKLHFE_01578 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CIEKLHFE_01579 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CIEKLHFE_01580 5.5e-53
CIEKLHFE_01582 2.7e-34 S YSIRK type signal peptide
CIEKLHFE_01583 1.9e-110 F DNA/RNA non-specific endonuclease
CIEKLHFE_01584 2e-75 S cog cog0433
CIEKLHFE_01585 0.0 uvrA3 L excinuclease ABC, A subunit
CIEKLHFE_01586 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
CIEKLHFE_01587 2.1e-114 3.6.1.27 I Acid phosphatase homologues
CIEKLHFE_01588 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
CIEKLHFE_01589 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIEKLHFE_01590 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
CIEKLHFE_01591 9.3e-204 pbpX1 V Beta-lactamase
CIEKLHFE_01592 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
CIEKLHFE_01593 7.5e-95 S ECF-type riboflavin transporter, S component
CIEKLHFE_01594 1.3e-229 S Putative peptidoglycan binding domain
CIEKLHFE_01595 9e-83 K Acetyltransferase (GNAT) domain
CIEKLHFE_01596 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CIEKLHFE_01604 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
CIEKLHFE_01605 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
CIEKLHFE_01606 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIEKLHFE_01607 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIEKLHFE_01608 1.7e-29 secG U Preprotein translocase
CIEKLHFE_01609 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CIEKLHFE_01610 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CIEKLHFE_01612 1.1e-07
CIEKLHFE_01613 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
CIEKLHFE_01614 3.2e-38
CIEKLHFE_01620 4e-19
CIEKLHFE_01622 7.7e-50 L PFAM IS66 Orf2 family protein
CIEKLHFE_01624 3.9e-136 L Transposase and inactivated derivatives
CIEKLHFE_01625 1.1e-71 2.5.1.74 H UbiA prenyltransferase family
CIEKLHFE_01626 7.7e-26
CIEKLHFE_01627 5.7e-84 S PFAM Archaeal ATPase
CIEKLHFE_01628 2.2e-85 S PFAM Archaeal ATPase
CIEKLHFE_01629 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CIEKLHFE_01631 2e-178 MA20_14895 S Conserved hypothetical protein 698
CIEKLHFE_01632 1.1e-83 dps P Belongs to the Dps family
CIEKLHFE_01633 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
CIEKLHFE_01634 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CIEKLHFE_01635 1.8e-58 S Putative adhesin
CIEKLHFE_01636 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
CIEKLHFE_01637 2e-234 mepA V MATE efflux family protein
CIEKLHFE_01638 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
CIEKLHFE_01639 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
CIEKLHFE_01642 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIEKLHFE_01643 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIEKLHFE_01644 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIEKLHFE_01645 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CIEKLHFE_01646 3.2e-181 ccpA K catabolite control protein A
CIEKLHFE_01647 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CIEKLHFE_01648 4.3e-55
CIEKLHFE_01649 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CIEKLHFE_01650 2.1e-92 yutD S Protein of unknown function (DUF1027)
CIEKLHFE_01651 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CIEKLHFE_01652 3.7e-100 S Protein of unknown function (DUF1461)
CIEKLHFE_01653 6.8e-116 dedA S SNARE-like domain protein
CIEKLHFE_01654 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
CIEKLHFE_01655 1e-15 S Domain of Unknown Function with PDB structure (DUF3850)
CIEKLHFE_01657 2.5e-89 M Protein of unknown function (DUF3737)
CIEKLHFE_01658 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
CIEKLHFE_01659 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
CIEKLHFE_01660 7.7e-67 S SdpI/YhfL protein family
CIEKLHFE_01661 4.4e-129 K Transcriptional regulatory protein, C terminal
CIEKLHFE_01662 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
CIEKLHFE_01663 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIEKLHFE_01664 1.1e-104 vanZ V VanZ like family
CIEKLHFE_01665 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
CIEKLHFE_01666 4.9e-217 EGP Major facilitator Superfamily
CIEKLHFE_01667 1.7e-195 ampC V Beta-lactamase
CIEKLHFE_01670 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
CIEKLHFE_01671 1.7e-129 manY G PTS system
CIEKLHFE_01672 1e-173 manN G system, mannose fructose sorbose family IID component
CIEKLHFE_01673 1.1e-62 manO S Domain of unknown function (DUF956)
CIEKLHFE_01674 3.3e-158 K Transcriptional regulator
CIEKLHFE_01675 1.3e-85 maa S transferase hexapeptide repeat
CIEKLHFE_01676 6.8e-243 cycA E Amino acid permease
CIEKLHFE_01677 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CIEKLHFE_01678 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CIEKLHFE_01679 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CIEKLHFE_01680 0.0 mtlR K Mga helix-turn-helix domain
CIEKLHFE_01681 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
CIEKLHFE_01682 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIEKLHFE_01683 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
CIEKLHFE_01684 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
CIEKLHFE_01685 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
CIEKLHFE_01686 2.1e-32
CIEKLHFE_01687 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
CIEKLHFE_01688 2.3e-156 K Helix-turn-helix XRE-family like proteins
CIEKLHFE_01689 3.9e-298 V ABC transporter transmembrane region
CIEKLHFE_01690 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
CIEKLHFE_01691 1.7e-193 S TerB-C domain
CIEKLHFE_01692 1.4e-16
CIEKLHFE_01694 1.8e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
CIEKLHFE_01695 1.1e-135 V ABC transporter transmembrane region
CIEKLHFE_01696 5.2e-170 degV S DegV family
CIEKLHFE_01697 3.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
CIEKLHFE_01698 1.3e-159 degV S EDD domain protein, DegV family
CIEKLHFE_01699 1.1e-66
CIEKLHFE_01700 0.0 FbpA K Fibronectin-binding protein
CIEKLHFE_01701 1.2e-188 K Periplasmic binding protein-like domain
CIEKLHFE_01702 2e-106 K Transcriptional regulator, AbiEi antitoxin
CIEKLHFE_01703 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
CIEKLHFE_01704 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CIEKLHFE_01705 3.5e-145 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
CIEKLHFE_01706 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
CIEKLHFE_01707 3.2e-165 lacR K Transcriptional regulator
CIEKLHFE_01708 0.0 lacS G Transporter
CIEKLHFE_01709 0.0 lacZ 3.2.1.23 G -beta-galactosidase
CIEKLHFE_01710 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CIEKLHFE_01711 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CIEKLHFE_01712 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CIEKLHFE_01713 5.5e-36
CIEKLHFE_01714 6.4e-71 scrR K Periplasmic binding protein domain
CIEKLHFE_01715 2.2e-89
CIEKLHFE_01716 3e-09 isdH M Iron Transport-associated domain
CIEKLHFE_01717 6.3e-123 M Iron Transport-associated domain
CIEKLHFE_01718 8.7e-159 isdE P Periplasmic binding protein
CIEKLHFE_01719 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIEKLHFE_01720 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
CIEKLHFE_01721 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CIEKLHFE_01722 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
CIEKLHFE_01723 1.3e-38 S RelB antitoxin
CIEKLHFE_01724 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
CIEKLHFE_01725 0.0 S membrane
CIEKLHFE_01726 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
CIEKLHFE_01727 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CIEKLHFE_01728 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CIEKLHFE_01729 4e-119 gluP 3.4.21.105 S Rhomboid family
CIEKLHFE_01730 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
CIEKLHFE_01731 1.5e-65 yqhL P Rhodanese-like protein
CIEKLHFE_01732 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIEKLHFE_01733 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
CIEKLHFE_01734 2e-263 glnA 6.3.1.2 E glutamine synthetase
CIEKLHFE_01735 6.7e-170
CIEKLHFE_01736 6e-148
CIEKLHFE_01737 1.9e-21
CIEKLHFE_01740 1.9e-11
CIEKLHFE_01741 1.2e-128 S interspecies interaction between organisms
CIEKLHFE_01743 9.1e-10 K peptidyl-tyrosine sulfation
CIEKLHFE_01744 7.1e-263 E ABC transporter, substratebinding protein
CIEKLHFE_01745 3.7e-66 K Helix-turn-helix domain, rpiR family
CIEKLHFE_01746 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
CIEKLHFE_01747 8.4e-90 nanK GK ROK family
CIEKLHFE_01748 2.3e-56 G Xylose isomerase domain protein TIM barrel
CIEKLHFE_01749 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CIEKLHFE_01750 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CIEKLHFE_01751 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
CIEKLHFE_01752 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
CIEKLHFE_01753 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CIEKLHFE_01754 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CIEKLHFE_01755 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CIEKLHFE_01756 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
CIEKLHFE_01757 1.7e-113 tdk 2.7.1.21 F thymidine kinase
CIEKLHFE_01758 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CIEKLHFE_01759 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CIEKLHFE_01760 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CIEKLHFE_01761 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CIEKLHFE_01762 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
CIEKLHFE_01763 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIEKLHFE_01764 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIEKLHFE_01765 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIEKLHFE_01766 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIEKLHFE_01767 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIEKLHFE_01768 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIEKLHFE_01769 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CIEKLHFE_01770 2e-30 ywzB S Protein of unknown function (DUF1146)
CIEKLHFE_01771 1.2e-177 mbl D Cell shape determining protein MreB Mrl
CIEKLHFE_01772 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CIEKLHFE_01773 3.3e-33 S Protein of unknown function (DUF2969)
CIEKLHFE_01774 4.7e-216 rodA D Belongs to the SEDS family
CIEKLHFE_01775 1.8e-78 usp6 T universal stress protein
CIEKLHFE_01776 8.4e-39
CIEKLHFE_01777 6.3e-238 rarA L recombination factor protein RarA
CIEKLHFE_01778 1.3e-84 yueI S Protein of unknown function (DUF1694)
CIEKLHFE_01779 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIEKLHFE_01780 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CIEKLHFE_01781 6.2e-213 iscS2 2.8.1.7 E Aminotransferase class V
CIEKLHFE_01782 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIEKLHFE_01783 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
CIEKLHFE_01784 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CIEKLHFE_01785 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CIEKLHFE_01786 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
CIEKLHFE_01787 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
CIEKLHFE_01788 1.5e-94 S Protein of unknown function (DUF3990)
CIEKLHFE_01789 6.5e-44
CIEKLHFE_01791 0.0 3.6.3.8 P P-type ATPase
CIEKLHFE_01792 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
CIEKLHFE_01793 2.5e-52
CIEKLHFE_01794 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CIEKLHFE_01795 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CIEKLHFE_01796 5.7e-126 S Haloacid dehalogenase-like hydrolase
CIEKLHFE_01797 2.3e-108 radC L DNA repair protein
CIEKLHFE_01798 2.4e-176 mreB D cell shape determining protein MreB
CIEKLHFE_01799 2e-147 mreC M Involved in formation and maintenance of cell shape
CIEKLHFE_01800 2.7e-94 mreD
CIEKLHFE_01801 1.6e-295 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CIEKLHFE_01802 5.4e-203 xerS L Belongs to the 'phage' integrase family
CIEKLHFE_01803 4.1e-67
CIEKLHFE_01804 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
CIEKLHFE_01805 5.8e-211 M Glycosyl hydrolases family 25
CIEKLHFE_01806 2.9e-277 V ABC transporter transmembrane region
CIEKLHFE_01807 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
CIEKLHFE_01808 3.1e-130 T Transcriptional regulatory protein, C terminal
CIEKLHFE_01809 5.2e-187 T GHKL domain
CIEKLHFE_01810 3.4e-76 S Peptidase propeptide and YPEB domain
CIEKLHFE_01811 2.5e-72 S Peptidase propeptide and YPEB domain
CIEKLHFE_01812 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
CIEKLHFE_01813 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
CIEKLHFE_01814 7e-68 V ABC transporter transmembrane region
CIEKLHFE_01815 9e-161 V ABC transporter transmembrane region
CIEKLHFE_01816 8.1e-91 cjaA ET ABC transporter substrate-binding protein
CIEKLHFE_01817 3e-53 cjaA ET ABC transporter substrate-binding protein
CIEKLHFE_01818 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIEKLHFE_01819 2e-110 P ABC transporter permease
CIEKLHFE_01820 9.6e-110 papP P ABC transporter, permease protein
CIEKLHFE_01822 8.8e-62 yodB K Transcriptional regulator, HxlR family
CIEKLHFE_01823 5e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIEKLHFE_01824 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CIEKLHFE_01825 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIEKLHFE_01826 1.5e-72 S Aminoacyl-tRNA editing domain
CIEKLHFE_01827 1.2e-54 S Abi-like protein
CIEKLHFE_01828 8e-224 S SLAP domain
CIEKLHFE_01829 3.9e-128 S CAAX protease self-immunity
CIEKLHFE_01830 1.9e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CIEKLHFE_01831 5.7e-69 rplI J Binds to the 23S rRNA
CIEKLHFE_01832 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CIEKLHFE_01833 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CIEKLHFE_01834 4e-57 asp S Asp23 family, cell envelope-related function
CIEKLHFE_01835 7.6e-305 yloV S DAK2 domain fusion protein YloV
CIEKLHFE_01836 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CIEKLHFE_01837 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CIEKLHFE_01838 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIEKLHFE_01839 1.1e-192 oppD P Belongs to the ABC transporter superfamily
CIEKLHFE_01840 1.5e-170 oppF P Belongs to the ABC transporter superfamily
CIEKLHFE_01841 2.6e-172 oppB P ABC transporter permease
CIEKLHFE_01842 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
CIEKLHFE_01843 9.7e-46 oppA E ABC transporter substrate-binding protein
CIEKLHFE_01844 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
CIEKLHFE_01845 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
CIEKLHFE_01846 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
CIEKLHFE_01847 5.9e-09
CIEKLHFE_01848 4.4e-43
CIEKLHFE_01849 8.7e-66 2.7.1.191 G PTS system fructose IIA component
CIEKLHFE_01850 0.0 3.6.3.8 P P-type ATPase
CIEKLHFE_01851 4.9e-125
CIEKLHFE_01852 1.2e-241 S response to antibiotic
CIEKLHFE_01858 2.9e-07
CIEKLHFE_01859 4.3e-24 S ASCH domain
CIEKLHFE_01860 2.2e-101 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
CIEKLHFE_01862 2.2e-30
CIEKLHFE_01863 5.4e-111 K Belongs to the N(4) N(6)-methyltransferase family
CIEKLHFE_01864 8.3e-85 L transposase activity
CIEKLHFE_01865 3.2e-215 S Terminase RNAseH like domain
CIEKLHFE_01866 4.9e-216 S Phage portal protein, SPP1 Gp6-like
CIEKLHFE_01867 2.2e-165 S Phage minor capsid protein 2
CIEKLHFE_01869 1e-36 S Phage minor structural protein GP20
CIEKLHFE_01870 4.6e-154 gpG
CIEKLHFE_01871 2.4e-44
CIEKLHFE_01872 1.6e-39 S Minor capsid protein
CIEKLHFE_01873 4e-31 S Minor capsid protein
CIEKLHFE_01874 3e-51 S Minor capsid protein from bacteriophage
CIEKLHFE_01875 3.5e-83 N domain, Protein
CIEKLHFE_01876 8.7e-35
CIEKLHFE_01877 1.6e-85 S Bacteriophage Gp15 protein
CIEKLHFE_01878 0.0 xkdO D NLP P60 protein
CIEKLHFE_01879 3.3e-109 S phage tail
CIEKLHFE_01880 0.0 S Phage minor structural protein
CIEKLHFE_01882 3.8e-06 S Domain of unknown function (DUF2479)
CIEKLHFE_01890 1.8e-38 S Bacteriophage holin of superfamily 6 (Holin_LLH)
CIEKLHFE_01891 2.3e-103 M hydrolase, family 25
CIEKLHFE_01897 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CIEKLHFE_01898 0.0 uup S ABC transporter, ATP-binding protein
CIEKLHFE_01899 2.7e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
CIEKLHFE_01900 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CIEKLHFE_01901 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CIEKLHFE_01902 7.7e-22
CIEKLHFE_01903 9.3e-64 L PFAM IS66 Orf2 family protein
CIEKLHFE_01904 8.7e-34 S Transposase C of IS166 homeodomain
CIEKLHFE_01905 1.9e-245 L Transposase IS66 family
CIEKLHFE_01906 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CIEKLHFE_01907 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
CIEKLHFE_01908 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
CIEKLHFE_01909 2.2e-85 S ECF transporter, substrate-specific component
CIEKLHFE_01910 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
CIEKLHFE_01911 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CIEKLHFE_01912 1.8e-59 yabA L Involved in initiation control of chromosome replication
CIEKLHFE_01913 1.5e-155 holB 2.7.7.7 L DNA polymerase III
CIEKLHFE_01914 8.9e-53 yaaQ S Cyclic-di-AMP receptor
CIEKLHFE_01915 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CIEKLHFE_01916 1.1e-34 S Protein of unknown function (DUF2508)
CIEKLHFE_01917 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIEKLHFE_01918 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CIEKLHFE_01919 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
CIEKLHFE_01920 5.7e-106 2.4.1.58 GT8 M family 8
CIEKLHFE_01921 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIEKLHFE_01922 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CIEKLHFE_01923 9e-26
CIEKLHFE_01924 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
CIEKLHFE_01925 1.9e-139 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
CIEKLHFE_01926 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CIEKLHFE_01927 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIEKLHFE_01928 1.5e-11 GT2,GT4 M family 8
CIEKLHFE_01929 2.8e-90 L An automated process has identified a potential problem with this gene model
CIEKLHFE_01930 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
CIEKLHFE_01931 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIEKLHFE_01932 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIEKLHFE_01933 6.5e-154 pstA P Phosphate transport system permease protein PstA
CIEKLHFE_01934 1.9e-162 pstC P probably responsible for the translocation of the substrate across the membrane
CIEKLHFE_01935 2.8e-157 pstS P Phosphate
CIEKLHFE_01936 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CIEKLHFE_01937 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIEKLHFE_01938 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
CIEKLHFE_01939 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CIEKLHFE_01940 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CIEKLHFE_01941 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
CIEKLHFE_01942 1.7e-34
CIEKLHFE_01943 1.2e-94 sigH K Belongs to the sigma-70 factor family
CIEKLHFE_01944 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIEKLHFE_01945 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CIEKLHFE_01946 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIEKLHFE_01947 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIEKLHFE_01948 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CIEKLHFE_01949 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
CIEKLHFE_01950 4.1e-52
CIEKLHFE_01951 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
CIEKLHFE_01952 7.3e-44
CIEKLHFE_01953 5.4e-183 S AAA domain
CIEKLHFE_01954 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIEKLHFE_01955 1.4e-23
CIEKLHFE_01956 7.3e-161 czcD P cation diffusion facilitator family transporter
CIEKLHFE_01957 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
CIEKLHFE_01958 6e-132 S membrane transporter protein
CIEKLHFE_01959 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CIEKLHFE_01960 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
CIEKLHFE_01961 1.2e-49 S Protein of unknown function (DUF3021)
CIEKLHFE_01962 2.8e-65 K LytTr DNA-binding domain
CIEKLHFE_01963 1.2e-10
CIEKLHFE_01964 1.7e-22 blpT
CIEKLHFE_01965 4.6e-27 S Enterocin A Immunity
CIEKLHFE_01968 1.3e-69 doc S Prophage maintenance system killer protein
CIEKLHFE_01969 2.9e-31
CIEKLHFE_01970 0.0 pepF E oligoendopeptidase F
CIEKLHFE_01971 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CIEKLHFE_01972 1.8e-111 S Protein of unknown function (DUF554)
CIEKLHFE_01973 1.2e-30
CIEKLHFE_01974 1.4e-34
CIEKLHFE_01975 5e-72 rimL J Acetyltransferase (GNAT) domain
CIEKLHFE_01976 8.3e-58
CIEKLHFE_01977 8.9e-292 S ABC transporter
CIEKLHFE_01978 2.4e-136 thrE S Putative threonine/serine exporter
CIEKLHFE_01979 1.1e-83 S Threonine/Serine exporter, ThrE
CIEKLHFE_01980 9.1e-112 yvpB S Peptidase_C39 like family
CIEKLHFE_01981 2.5e-68
CIEKLHFE_01982 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIEKLHFE_01983 5.5e-77 nrdI F NrdI Flavodoxin like
CIEKLHFE_01984 4.7e-221 tnpB L Putative transposase DNA-binding domain
CIEKLHFE_01985 3.3e-112
CIEKLHFE_01986 2.9e-279 S O-antigen ligase like membrane protein
CIEKLHFE_01987 3.9e-42
CIEKLHFE_01988 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
CIEKLHFE_01989 5e-88 M NlpC/P60 family
CIEKLHFE_01990 1.4e-136 M NlpC P60 family protein
CIEKLHFE_01991 2.6e-118 M NlpC/P60 family
CIEKLHFE_01992 1.6e-41
CIEKLHFE_01993 3.5e-175 S Cysteine-rich secretory protein family
CIEKLHFE_01994 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIEKLHFE_01996 1.8e-163
CIEKLHFE_01997 7.8e-26 K Acetyltransferase (GNAT) domain
CIEKLHFE_01999 0.0 ydgH S MMPL family
CIEKLHFE_02000 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
CIEKLHFE_02001 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
CIEKLHFE_02002 1.8e-154 corA P CorA-like Mg2+ transporter protein
CIEKLHFE_02003 6.7e-240 G Bacterial extracellular solute-binding protein
CIEKLHFE_02004 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
CIEKLHFE_02005 1.8e-145 gtsC P Binding-protein-dependent transport system inner membrane component
CIEKLHFE_02006 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
CIEKLHFE_02007 1.9e-203 malK P ATPases associated with a variety of cellular activities
CIEKLHFE_02008 1.3e-281 pipD E Dipeptidase
CIEKLHFE_02009 1.9e-158 endA F DNA RNA non-specific endonuclease
CIEKLHFE_02010 8e-182 dnaQ 2.7.7.7 L EXOIII
CIEKLHFE_02011 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CIEKLHFE_02012 3e-116 yviA S Protein of unknown function (DUF421)
CIEKLHFE_02013 1.1e-56 S Protein of unknown function (DUF3290)
CIEKLHFE_02017 2.9e-08
CIEKLHFE_02019 5.7e-109 K BRO family, N-terminal domain
CIEKLHFE_02021 9.8e-18 K Transcriptional
CIEKLHFE_02023 6.7e-12
CIEKLHFE_02025 9.1e-76 sip L Belongs to the 'phage' integrase family
CIEKLHFE_02041 2.9e-86 V N-6 DNA Methylase
CIEKLHFE_02042 2.4e-99 L An automated process has identified a potential problem with this gene model
CIEKLHFE_02043 8.3e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CIEKLHFE_02044 3.5e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CIEKLHFE_02045 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
CIEKLHFE_02046 9.7e-205 gatC G PTS system sugar-specific permease component
CIEKLHFE_02047 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
CIEKLHFE_02049 7.9e-16 L An automated process has identified a potential problem with this gene model
CIEKLHFE_02050 9.4e-51 L An automated process has identified a potential problem with this gene model
CIEKLHFE_02052 1e-66 doc S Fic/DOC family
CIEKLHFE_02053 4.1e-34
CIEKLHFE_02055 4.9e-24 S CAAX protease self-immunity
CIEKLHFE_02057 1.3e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CIEKLHFE_02059 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIEKLHFE_02060 2.8e-23 relB L Addiction module antitoxin, RelB DinJ family
CIEKLHFE_02061 6.1e-48 E Pfam:DUF955
CIEKLHFE_02063 4e-60 L Resolvase, N terminal domain
CIEKLHFE_02064 8.7e-26 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CIEKLHFE_02065 2.3e-101 L An automated process has identified a potential problem with this gene model
CIEKLHFE_02066 8.1e-175 ulaG S Beta-lactamase superfamily domain
CIEKLHFE_02067 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CIEKLHFE_02068 1.3e-231 ulaA S PTS system sugar-specific permease component
CIEKLHFE_02069 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
CIEKLHFE_02070 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
CIEKLHFE_02071 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
CIEKLHFE_02072 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CIEKLHFE_02073 5.2e-68 L haloacid dehalogenase-like hydrolase
CIEKLHFE_02074 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CIEKLHFE_02075 1.4e-16 L Transposase
CIEKLHFE_02076 1.9e-12 L Transposase
CIEKLHFE_02077 5.9e-13 K Acetyltransferase (GNAT) domain
CIEKLHFE_02078 1.2e-222 patA 2.6.1.1 E Aminotransferase
CIEKLHFE_02079 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CIEKLHFE_02080 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
CIEKLHFE_02081 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CIEKLHFE_02082 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIEKLHFE_02083 8.5e-60
CIEKLHFE_02084 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
CIEKLHFE_02085 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIEKLHFE_02086 5.9e-37 M domain protein
CIEKLHFE_02088 6.5e-249 yjjP S Putative threonine/serine exporter
CIEKLHFE_02089 2.6e-177 citR K Putative sugar-binding domain
CIEKLHFE_02090 1.5e-50
CIEKLHFE_02091 5.5e-09
CIEKLHFE_02092 2.9e-66 S Domain of unknown function DUF1828
CIEKLHFE_02093 1.5e-95 S UPF0397 protein
CIEKLHFE_02094 0.0 ykoD P ABC transporter, ATP-binding protein
CIEKLHFE_02095 3.6e-146 cbiQ P cobalt transport
CIEKLHFE_02096 3.5e-21
CIEKLHFE_02097 9.3e-72 yeaL S Protein of unknown function (DUF441)
CIEKLHFE_02098 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
CIEKLHFE_02099 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
CIEKLHFE_02100 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
CIEKLHFE_02101 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CIEKLHFE_02102 1.9e-153 ydjP I Alpha/beta hydrolase family
CIEKLHFE_02103 5.7e-272 P Sodium:sulfate symporter transmembrane region
CIEKLHFE_02104 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
CIEKLHFE_02105 1.3e-29 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
CIEKLHFE_02106 1.3e-12 L TIGRFAM transposase, IS605 OrfB family
CIEKLHFE_02107 1.2e-11 S Transposase C of IS166 homeodomain
CIEKLHFE_02108 1.4e-59 XK27_01125 L IS66 Orf2 like protein
CIEKLHFE_02110 4.4e-169 ppaC 3.6.1.1 C inorganic pyrophosphatase
CIEKLHFE_02111 2.8e-182 K Transcriptional regulator
CIEKLHFE_02112 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIEKLHFE_02113 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIEKLHFE_02114 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CIEKLHFE_02115 0.0 snf 2.7.11.1 KL domain protein
CIEKLHFE_02116 2e-35
CIEKLHFE_02118 3.8e-104 pncA Q Isochorismatase family
CIEKLHFE_02119 4.9e-118
CIEKLHFE_02122 3.6e-63
CIEKLHFE_02123 1.4e-34
CIEKLHFE_02124 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
CIEKLHFE_02125 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
CIEKLHFE_02126 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
CIEKLHFE_02128 1.9e-83 K Transcriptional regulator
CIEKLHFE_02129 6.1e-61 K Transcriptional regulator
CIEKLHFE_02130 2e-225 S cog cog1373
CIEKLHFE_02131 9.7e-146 S haloacid dehalogenase-like hydrolase
CIEKLHFE_02132 2.5e-226 pbuG S permease
CIEKLHFE_02133 2.1e-111 S Fic/DOC family
CIEKLHFE_02134 5.5e-38 L Protein of unknown function (DUF3991)
CIEKLHFE_02135 7.2e-43 S COG0790 FOG TPR repeat, SEL1 subfamily
CIEKLHFE_02136 1.6e-15 L hmm pf00665
CIEKLHFE_02137 2.9e-15 M LysM domain protein
CIEKLHFE_02138 3.8e-48 M LysM domain protein
CIEKLHFE_02139 1.4e-86 C Aldo keto reductase
CIEKLHFE_02140 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
CIEKLHFE_02141 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CIEKLHFE_02142 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CIEKLHFE_02143 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
CIEKLHFE_02144 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CIEKLHFE_02145 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIEKLHFE_02146 5.8e-152 dprA LU DNA protecting protein DprA
CIEKLHFE_02147 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIEKLHFE_02148 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CIEKLHFE_02149 1.9e-94 yjcE P Sodium proton antiporter
CIEKLHFE_02150 1.5e-40 yjcE P Sodium proton antiporter
CIEKLHFE_02151 1.1e-66 yjcE P NhaP-type Na H and K H
CIEKLHFE_02152 7.1e-36 yozE S Belongs to the UPF0346 family
CIEKLHFE_02153 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
CIEKLHFE_02154 1.2e-107 hlyIII S protein, hemolysin III
CIEKLHFE_02155 3.3e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CIEKLHFE_02156 8.8e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CIEKLHFE_02157 4.3e-86 3.4.21.96 S SLAP domain
CIEKLHFE_02158 8.4e-128 yagE E Amino acid permease
CIEKLHFE_02159 9.7e-65 yagE E amino acid
CIEKLHFE_02160 4e-145 yfeO P Voltage gated chloride channel
CIEKLHFE_02161 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
CIEKLHFE_02162 2.8e-52
CIEKLHFE_02163 3.8e-42
CIEKLHFE_02164 7e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIEKLHFE_02165 1.3e-298 ybeC E amino acid
CIEKLHFE_02166 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
CIEKLHFE_02167 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
CIEKLHFE_02168 2.5e-39 rpmE2 J Ribosomal protein L31
CIEKLHFE_02169 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CIEKLHFE_02170 4.8e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CIEKLHFE_02171 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CIEKLHFE_02172 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIEKLHFE_02173 9.9e-129 S (CBS) domain
CIEKLHFE_02174 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CIEKLHFE_02175 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CIEKLHFE_02176 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIEKLHFE_02177 1.6e-33 yabO J S4 domain protein
CIEKLHFE_02178 6.8e-60 divIC D Septum formation initiator
CIEKLHFE_02179 6.3e-63 yabR J S1 RNA binding domain
CIEKLHFE_02180 3.4e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CIEKLHFE_02181 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIEKLHFE_02182 3.3e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CIEKLHFE_02183 2.8e-193 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIEKLHFE_02184 7.8e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CIEKLHFE_02185 8.4e-56 S Domain of unknown function (DUF4767)
CIEKLHFE_02186 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CIEKLHFE_02187 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
CIEKLHFE_02188 3.2e-101 3.6.1.27 I Acid phosphatase homologues
CIEKLHFE_02189 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CIEKLHFE_02190 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CIEKLHFE_02191 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
CIEKLHFE_02192 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CIEKLHFE_02193 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIEKLHFE_02194 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIEKLHFE_02195 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIEKLHFE_02196 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CIEKLHFE_02197 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIEKLHFE_02198 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
CIEKLHFE_02199 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIEKLHFE_02200 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CIEKLHFE_02201 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIEKLHFE_02202 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIEKLHFE_02203 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIEKLHFE_02204 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CIEKLHFE_02205 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CIEKLHFE_02206 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIEKLHFE_02207 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIEKLHFE_02208 2.3e-24 rpmD J Ribosomal protein L30
CIEKLHFE_02209 1.3e-70 rplO J Binds to the 23S rRNA
CIEKLHFE_02210 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CIEKLHFE_02211 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CIEKLHFE_02212 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CIEKLHFE_02213 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CIEKLHFE_02214 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIEKLHFE_02215 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIEKLHFE_02216 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIEKLHFE_02217 1.4e-60 rplQ J Ribosomal protein L17
CIEKLHFE_02218 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIEKLHFE_02219 7.8e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIEKLHFE_02220 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIEKLHFE_02221 4.8e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CIEKLHFE_02222 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CIEKLHFE_02223 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
CIEKLHFE_02224 8.9e-133 L Phage integrase family
CIEKLHFE_02225 1.4e-15 S cog cog1373
CIEKLHFE_02226 1.4e-156 hipB K Helix-turn-helix
CIEKLHFE_02227 6e-151 I alpha/beta hydrolase fold
CIEKLHFE_02228 1.4e-110 yjbF S SNARE associated Golgi protein
CIEKLHFE_02229 7.5e-100 J Acetyltransferase (GNAT) domain
CIEKLHFE_02230 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIEKLHFE_02231 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
CIEKLHFE_02232 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
CIEKLHFE_02233 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
CIEKLHFE_02234 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
CIEKLHFE_02235 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
CIEKLHFE_02236 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CIEKLHFE_02237 9.7e-52 S Iron-sulfur cluster assembly protein
CIEKLHFE_02238 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CIEKLHFE_02239 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CIEKLHFE_02240 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
CIEKLHFE_02241 1.5e-203 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CIEKLHFE_02242 3.9e-46 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CIEKLHFE_02243 1.5e-31 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIEKLHFE_02244 1.2e-225 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)