ORF_ID e_value Gene_name EC_number CAZy COGs Description
HLDHABGM_00001 7.5e-103 G Phosphoglycerate mutase family
HLDHABGM_00002 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HLDHABGM_00004 3.4e-129 S (CBS) domain
HLDHABGM_00005 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HLDHABGM_00006 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLDHABGM_00007 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLDHABGM_00008 7.4e-40 yabO J S4 domain protein
HLDHABGM_00009 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
HLDHABGM_00010 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDHABGM_00011 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
HLDHABGM_00012 9.3e-204 pbpX1 V Beta-lactamase
HLDHABGM_00013 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HLDHABGM_00014 7.5e-95 S ECF-type riboflavin transporter, S component
HLDHABGM_00015 1.3e-229 S Putative peptidoglycan binding domain
HLDHABGM_00016 8.8e-58 S Peptidase propeptide and YPEB domain
HLDHABGM_00017 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLDHABGM_00018 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HLDHABGM_00019 7.1e-98 E GDSL-like Lipase/Acylhydrolase
HLDHABGM_00020 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
HLDHABGM_00021 1.6e-143 aatB ET ABC transporter substrate-binding protein
HLDHABGM_00022 1e-105 glnQ 3.6.3.21 E ABC transporter
HLDHABGM_00023 1.5e-107 glnP P ABC transporter permease
HLDHABGM_00024 0.0 helD 3.6.4.12 L DNA helicase
HLDHABGM_00025 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HLDHABGM_00026 1.4e-126 pgm3 G Phosphoglycerate mutase family
HLDHABGM_00027 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HLDHABGM_00028 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLDHABGM_00029 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLDHABGM_00030 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLDHABGM_00031 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLDHABGM_00032 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HLDHABGM_00033 9.5e-31
HLDHABGM_00034 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLDHABGM_00035 3.1e-71 2.5.1.74 H UbiA prenyltransferase family
HLDHABGM_00036 7.7e-26
HLDHABGM_00037 5.7e-84 S PFAM Archaeal ATPase
HLDHABGM_00038 2.2e-85 S PFAM Archaeal ATPase
HLDHABGM_00039 9.1e-54 papP P ABC transporter, permease protein
HLDHABGM_00040 5.3e-116 P ABC transporter permease
HLDHABGM_00041 1.5e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLDHABGM_00042 1e-156 cjaA ET ABC transporter substrate-binding protein
HLDHABGM_00043 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLDHABGM_00044 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLDHABGM_00045 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLDHABGM_00046 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HLDHABGM_00047 7.1e-158 metQ1 P Belongs to the nlpA lipoprotein family
HLDHABGM_00048 1.9e-25
HLDHABGM_00049 0.0 mco Q Multicopper oxidase
HLDHABGM_00050 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
HLDHABGM_00051 0.0 oppA E ABC transporter
HLDHABGM_00052 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
HLDHABGM_00053 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
HLDHABGM_00054 1e-137 S Protein of unknown function (DUF3100)
HLDHABGM_00055 9.7e-83 S An automated process has identified a potential problem with this gene model
HLDHABGM_00056 2.7e-151 I alpha/beta hydrolase fold
HLDHABGM_00057 2e-129 hipB K Helix-turn-helix
HLDHABGM_00058 1.4e-15 S cog cog1373
HLDHABGM_00059 1e-30 S cog cog1373
HLDHABGM_00060 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
HLDHABGM_00061 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HLDHABGM_00062 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLDHABGM_00063 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLDHABGM_00064 2.6e-35 yaaA S S4 domain protein YaaA
HLDHABGM_00065 4e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLDHABGM_00066 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLDHABGM_00067 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLDHABGM_00068 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HLDHABGM_00069 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLDHABGM_00070 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLDHABGM_00071 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HLDHABGM_00072 5.7e-69 rplI J Binds to the 23S rRNA
HLDHABGM_00073 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HLDHABGM_00074 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HLDHABGM_00075 3.7e-168 degV S DegV family
HLDHABGM_00076 4.2e-135 V ABC transporter transmembrane region
HLDHABGM_00077 3.3e-166 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HLDHABGM_00079 1.4e-16
HLDHABGM_00080 4.7e-227 I Protein of unknown function (DUF2974)
HLDHABGM_00081 9.2e-119 yhiD S MgtC family
HLDHABGM_00083 3.9e-131 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00084 1.3e-31
HLDHABGM_00085 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
HLDHABGM_00086 3.7e-130 ybbH_2 K rpiR family
HLDHABGM_00087 3.4e-195 S Bacterial protein of unknown function (DUF871)
HLDHABGM_00088 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLDHABGM_00089 1.8e-119 S Putative esterase
HLDHABGM_00090 1.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLDHABGM_00091 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
HLDHABGM_00093 8.5e-260 qacA EGP Major facilitator Superfamily
HLDHABGM_00094 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLDHABGM_00095 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLDHABGM_00096 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HLDHABGM_00097 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HLDHABGM_00098 9.4e-72
HLDHABGM_00099 8.2e-140 cof S haloacid dehalogenase-like hydrolase
HLDHABGM_00100 8.2e-230 pbuG S permease
HLDHABGM_00102 3.9e-33 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HLDHABGM_00103 3.2e-30 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HLDHABGM_00104 1.3e-33 UW LPXTG-motif cell wall anchor domain protein
HLDHABGM_00107 5.3e-80
HLDHABGM_00108 2e-295 S SLAP domain
HLDHABGM_00109 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLDHABGM_00110 1.6e-171 2.7.1.2 GK ROK family
HLDHABGM_00111 6.6e-44
HLDHABGM_00112 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLDHABGM_00113 4.8e-28
HLDHABGM_00116 4.3e-67 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00117 3.3e-147 malG P ABC transporter permease
HLDHABGM_00118 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
HLDHABGM_00119 5e-213 malE G Bacterial extracellular solute-binding protein
HLDHABGM_00120 6.8e-209 msmX P Belongs to the ABC transporter superfamily
HLDHABGM_00121 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HLDHABGM_00122 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HLDHABGM_00123 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HLDHABGM_00124 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HLDHABGM_00125 0.0 fhaB M Rib/alpha-like repeat
HLDHABGM_00126 9.3e-147 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HLDHABGM_00127 0.0 mtlR K Mga helix-turn-helix domain
HLDHABGM_00128 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLDHABGM_00129 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HLDHABGM_00130 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HLDHABGM_00131 6.8e-243 cycA E Amino acid permease
HLDHABGM_00132 1.3e-85 maa S transferase hexapeptide repeat
HLDHABGM_00133 3.3e-158 K Transcriptional regulator
HLDHABGM_00134 1.1e-62 manO S Domain of unknown function (DUF956)
HLDHABGM_00135 1e-173 manN G system, mannose fructose sorbose family IID component
HLDHABGM_00136 1.7e-129 manY G PTS system
HLDHABGM_00137 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HLDHABGM_00138 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HLDHABGM_00139 1.6e-294 L Nuclease-related domain
HLDHABGM_00140 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLDHABGM_00141 8.3e-106 S Repeat protein
HLDHABGM_00142 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HLDHABGM_00143 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLDHABGM_00144 5.4e-56 XK27_04120 S Putative amino acid metabolism
HLDHABGM_00145 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
HLDHABGM_00146 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLDHABGM_00147 6.7e-37
HLDHABGM_00148 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HLDHABGM_00149 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
HLDHABGM_00150 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLDHABGM_00151 2.8e-74 gpsB D DivIVA domain protein
HLDHABGM_00152 5.7e-149 ylmH S S4 domain protein
HLDHABGM_00153 1.7e-45 yggT S YGGT family
HLDHABGM_00154 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLDHABGM_00155 3.8e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLDHABGM_00156 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLDHABGM_00157 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLDHABGM_00158 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLDHABGM_00159 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLDHABGM_00160 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLDHABGM_00161 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HLDHABGM_00162 1.8e-54 ftsL D Cell division protein FtsL
HLDHABGM_00163 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLDHABGM_00164 6.3e-78 mraZ K Belongs to the MraZ family
HLDHABGM_00165 6.4e-54 S Protein of unknown function (DUF3397)
HLDHABGM_00167 2.7e-94 mreD
HLDHABGM_00168 2e-147 mreC M Involved in formation and maintenance of cell shape
HLDHABGM_00169 2.4e-176 mreB D cell shape determining protein MreB
HLDHABGM_00170 2.3e-108 radC L DNA repair protein
HLDHABGM_00171 5.7e-126 S Haloacid dehalogenase-like hydrolase
HLDHABGM_00172 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HLDHABGM_00173 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLDHABGM_00174 2.5e-52
HLDHABGM_00175 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
HLDHABGM_00176 0.0 3.6.3.8 P P-type ATPase
HLDHABGM_00178 6.5e-44
HLDHABGM_00179 1.5e-94 S Protein of unknown function (DUF3990)
HLDHABGM_00180 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HLDHABGM_00181 3.5e-62 2.4.1.83 GT2 S GtrA-like protein
HLDHABGM_00182 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HLDHABGM_00183 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLDHABGM_00184 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HLDHABGM_00185 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLDHABGM_00186 1.4e-212 iscS2 2.8.1.7 E Aminotransferase class V
HLDHABGM_00187 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLDHABGM_00188 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLDHABGM_00189 1.3e-84 yueI S Protein of unknown function (DUF1694)
HLDHABGM_00190 2.2e-238 rarA L recombination factor protein RarA
HLDHABGM_00191 8.4e-39
HLDHABGM_00192 1.8e-78 usp6 T universal stress protein
HLDHABGM_00193 4.7e-216 rodA D Belongs to the SEDS family
HLDHABGM_00194 3.3e-33 S Protein of unknown function (DUF2969)
HLDHABGM_00195 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HLDHABGM_00196 1.2e-177 mbl D Cell shape determining protein MreB Mrl
HLDHABGM_00197 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
HLDHABGM_00198 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLDHABGM_00199 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HLDHABGM_00200 3.5e-71 yqeY S YqeY-like protein
HLDHABGM_00201 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
HLDHABGM_00202 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLDHABGM_00203 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLDHABGM_00204 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
HLDHABGM_00205 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HLDHABGM_00206 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HLDHABGM_00207 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLDHABGM_00208 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLDHABGM_00209 1.4e-127 S Peptidase family M23
HLDHABGM_00210 4.8e-81 mutT 3.6.1.55 F NUDIX domain
HLDHABGM_00211 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HLDHABGM_00212 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLDHABGM_00213 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HLDHABGM_00214 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
HLDHABGM_00215 9.6e-124 skfE V ATPases associated with a variety of cellular activities
HLDHABGM_00216 4.5e-141
HLDHABGM_00217 5.1e-137
HLDHABGM_00218 6.7e-145
HLDHABGM_00219 1.4e-26
HLDHABGM_00220 5.5e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HLDHABGM_00221 7.5e-143
HLDHABGM_00222 9.7e-169
HLDHABGM_00223 6e-29 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HLDHABGM_00224 1.6e-227 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HLDHABGM_00225 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HLDHABGM_00226 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLDHABGM_00227 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HLDHABGM_00228 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HLDHABGM_00229 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HLDHABGM_00230 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLDHABGM_00231 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HLDHABGM_00232 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HLDHABGM_00233 1.6e-147 sip L Belongs to the 'phage' integrase family
HLDHABGM_00234 4.2e-13
HLDHABGM_00238 6e-14
HLDHABGM_00239 3e-59
HLDHABGM_00241 2.8e-13 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00242 2e-20 cro K Helix-turn-helix XRE-family like proteins
HLDHABGM_00244 1.1e-90 S AntA/AntB antirepressor
HLDHABGM_00249 7.2e-10
HLDHABGM_00250 5e-07 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00252 7.7e-48
HLDHABGM_00254 2.4e-59 S Protein of unknown function (DUF1071)
HLDHABGM_00255 4e-33 S Conserved phage C-terminus (Phg_2220_C)
HLDHABGM_00256 1.4e-51 dnaC L IstB-like ATP binding protein
HLDHABGM_00262 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
HLDHABGM_00263 2.1e-14
HLDHABGM_00271 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
HLDHABGM_00272 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
HLDHABGM_00273 1.5e-28 L Terminase small subunit
HLDHABGM_00274 1.8e-230 S Terminase-like family
HLDHABGM_00275 7e-142 S Protein of unknown function (DUF1073)
HLDHABGM_00276 1e-97 S Phage Mu protein F like protein
HLDHABGM_00277 1.1e-07 S Lysin motif
HLDHABGM_00278 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
HLDHABGM_00279 1.6e-58
HLDHABGM_00280 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HLDHABGM_00281 2.1e-30 S Protein of unknown function (DUF4054)
HLDHABGM_00282 1.5e-75
HLDHABGM_00283 2.9e-45
HLDHABGM_00284 8e-57
HLDHABGM_00285 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
HLDHABGM_00286 4e-56
HLDHABGM_00287 9e-27
HLDHABGM_00289 0.0 3.4.14.13 M Phage tail tape measure protein TP901
HLDHABGM_00290 1.2e-58 M LysM domain
HLDHABGM_00291 2.1e-46
HLDHABGM_00292 5.7e-104
HLDHABGM_00293 1.2e-48
HLDHABGM_00294 9.5e-33
HLDHABGM_00295 1.7e-125 Z012_12235 S Baseplate J-like protein
HLDHABGM_00296 1.1e-08
HLDHABGM_00297 1.6e-36
HLDHABGM_00303 7.1e-38
HLDHABGM_00304 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
HLDHABGM_00305 1.1e-07
HLDHABGM_00307 7.9e-19
HLDHABGM_00308 5e-29
HLDHABGM_00309 1e-95
HLDHABGM_00310 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
HLDHABGM_00312 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
HLDHABGM_00313 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDHABGM_00315 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HLDHABGM_00316 2.4e-43 K Helix-turn-helix
HLDHABGM_00317 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLDHABGM_00318 1.4e-226 pbuX F xanthine permease
HLDHABGM_00319 2.5e-152 msmR K AraC-like ligand binding domain
HLDHABGM_00320 4.4e-285 pipD E Dipeptidase
HLDHABGM_00321 1.3e-47 adk 2.7.4.3 F AAA domain
HLDHABGM_00322 2.1e-80 K acetyltransferase
HLDHABGM_00323 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLDHABGM_00324 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLDHABGM_00325 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLDHABGM_00326 4.5e-68 S Domain of unknown function (DUF1934)
HLDHABGM_00327 5.6e-36
HLDHABGM_00328 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLDHABGM_00329 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
HLDHABGM_00330 2.8e-135
HLDHABGM_00331 1.3e-258 glnPH2 P ABC transporter permease
HLDHABGM_00332 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLDHABGM_00333 6.4e-224 S Cysteine-rich secretory protein family
HLDHABGM_00334 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HLDHABGM_00335 1.4e-112
HLDHABGM_00336 2.2e-202 yibE S overlaps another CDS with the same product name
HLDHABGM_00337 4.9e-129 yibF S overlaps another CDS with the same product name
HLDHABGM_00338 8.7e-145 I alpha/beta hydrolase fold
HLDHABGM_00339 0.0 G Belongs to the glycosyl hydrolase 31 family
HLDHABGM_00340 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLDHABGM_00341 5.4e-13
HLDHABGM_00342 4.2e-101 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HLDHABGM_00343 2.5e-86 K GNAT family
HLDHABGM_00344 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
HLDHABGM_00345 4.7e-36 rbtT P Major Facilitator Superfamily
HLDHABGM_00346 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
HLDHABGM_00347 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLDHABGM_00348 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLDHABGM_00349 1.2e-155 pstA P Phosphate transport system permease protein PstA
HLDHABGM_00350 3.9e-163 pstC P probably responsible for the translocation of the substrate across the membrane
HLDHABGM_00351 2.8e-157 pstS P Phosphate
HLDHABGM_00352 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLDHABGM_00353 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLDHABGM_00354 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
HLDHABGM_00355 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLDHABGM_00356 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLDHABGM_00357 5.8e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HLDHABGM_00358 1.7e-34
HLDHABGM_00359 5.5e-95 sigH K Belongs to the sigma-70 factor family
HLDHABGM_00360 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLDHABGM_00361 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLDHABGM_00362 2.9e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLDHABGM_00363 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLDHABGM_00364 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLDHABGM_00365 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HLDHABGM_00366 1.9e-52
HLDHABGM_00367 3.9e-267 pepC 3.4.22.40 E Peptidase C1-like family
HLDHABGM_00368 1.1e-183 S AAA domain
HLDHABGM_00369 1.2e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLDHABGM_00370 1.4e-23
HLDHABGM_00371 7.3e-161 czcD P cation diffusion facilitator family transporter
HLDHABGM_00372 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
HLDHABGM_00373 6e-132 S membrane transporter protein
HLDHABGM_00374 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HLDHABGM_00375 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HLDHABGM_00376 1.2e-49 S Protein of unknown function (DUF3021)
HLDHABGM_00377 2.8e-65 K LytTr DNA-binding domain
HLDHABGM_00378 1.2e-10
HLDHABGM_00379 1.3e-55 K Acetyltransferase (GNAT) domain
HLDHABGM_00380 1.9e-12 L Transposase
HLDHABGM_00381 1.4e-16 L Transposase
HLDHABGM_00382 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HLDHABGM_00384 3.7e-13
HLDHABGM_00385 3.1e-12
HLDHABGM_00386 3.7e-18 ps115 K sequence-specific DNA binding
HLDHABGM_00387 4.7e-15 S Pfam:Peptidase_M78
HLDHABGM_00388 1.2e-54 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLDHABGM_00391 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HLDHABGM_00392 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
HLDHABGM_00393 1.8e-230 steT_1 E amino acid
HLDHABGM_00394 2.2e-139 puuD S peptidase C26
HLDHABGM_00396 2.4e-172 V HNH endonuclease
HLDHABGM_00397 6.4e-135 S PFAM Archaeal ATPase
HLDHABGM_00398 9.2e-248 yifK E Amino acid permease
HLDHABGM_00399 9.7e-234 cycA E Amino acid permease
HLDHABGM_00400 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HLDHABGM_00401 0.0 clpE O AAA domain (Cdc48 subfamily)
HLDHABGM_00402 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HLDHABGM_00403 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDHABGM_00404 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
HLDHABGM_00405 0.0 XK27_06780 V ABC transporter permease
HLDHABGM_00406 1.9e-36
HLDHABGM_00407 7.9e-291 ytgP S Polysaccharide biosynthesis protein
HLDHABGM_00408 2.7e-137 lysA2 M Glycosyl hydrolases family 25
HLDHABGM_00409 2.3e-133 S Protein of unknown function (DUF975)
HLDHABGM_00410 7.6e-177 pbpX2 V Beta-lactamase
HLDHABGM_00411 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLDHABGM_00412 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDHABGM_00413 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
HLDHABGM_00414 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDHABGM_00415 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
HLDHABGM_00416 4.1e-44
HLDHABGM_00417 1e-207 ywhK S Membrane
HLDHABGM_00418 7.4e-80 ykuL S (CBS) domain
HLDHABGM_00419 0.0 cadA P P-type ATPase
HLDHABGM_00420 2.8e-205 napA P Sodium/hydrogen exchanger family
HLDHABGM_00421 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HLDHABGM_00422 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HLDHABGM_00423 4.1e-276 V ABC transporter transmembrane region
HLDHABGM_00424 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
HLDHABGM_00425 5.4e-51
HLDHABGM_00426 4.2e-154 EGP Major facilitator Superfamily
HLDHABGM_00427 3e-111 ropB K Transcriptional regulator
HLDHABGM_00428 2.7e-120 S CAAX protease self-immunity
HLDHABGM_00429 1.6e-194 S DUF218 domain
HLDHABGM_00430 0.0 macB_3 V ABC transporter, ATP-binding protein
HLDHABGM_00431 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HLDHABGM_00432 2.8e-100 S ECF transporter, substrate-specific component
HLDHABGM_00433 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
HLDHABGM_00434 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
HLDHABGM_00435 1.3e-282 xylG 3.6.3.17 S ABC transporter
HLDHABGM_00436 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
HLDHABGM_00437 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
HLDHABGM_00438 4.8e-145 yeaE S Aldo/keto reductase family
HLDHABGM_00439 2.9e-277 V ABC transporter transmembrane region
HLDHABGM_00440 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HLDHABGM_00441 3.1e-130 T Transcriptional regulatory protein, C terminal
HLDHABGM_00442 5.2e-187 T GHKL domain
HLDHABGM_00443 3.4e-76 S Peptidase propeptide and YPEB domain
HLDHABGM_00444 2.5e-72 S Peptidase propeptide and YPEB domain
HLDHABGM_00445 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HLDHABGM_00446 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
HLDHABGM_00447 7e-68 V ABC transporter transmembrane region
HLDHABGM_00448 5.8e-160 V ABC transporter transmembrane region
HLDHABGM_00449 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLDHABGM_00451 2e-178 MA20_14895 S Conserved hypothetical protein 698
HLDHABGM_00452 1.1e-83 dps P Belongs to the Dps family
HLDHABGM_00453 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
HLDHABGM_00454 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HLDHABGM_00455 1.8e-58 S Putative adhesin
HLDHABGM_00456 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HLDHABGM_00457 2e-234 mepA V MATE efflux family protein
HLDHABGM_00459 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
HLDHABGM_00462 6.7e-66 xerS L Belongs to the 'phage' integrase family
HLDHABGM_00466 2.3e-197 L Probable transposase
HLDHABGM_00469 2.2e-118 U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLDHABGM_00470 3.8e-257 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLDHABGM_00474 2.3e-09
HLDHABGM_00475 1.7e-31 M NlpC/P60 family
HLDHABGM_00481 3.7e-22 L Probable transposase
HLDHABGM_00482 4.6e-77 traI 5.99.1.2 L DNA topoisomerase
HLDHABGM_00489 8.4e-265 S Fibronectin type III domain
HLDHABGM_00490 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLDHABGM_00491 3.4e-53
HLDHABGM_00493 4.6e-257 pepC 3.4.22.40 E aminopeptidase
HLDHABGM_00494 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLDHABGM_00495 5e-301 oppA E ABC transporter, substratebinding protein
HLDHABGM_00496 1.6e-310 oppA E ABC transporter, substratebinding protein
HLDHABGM_00497 9.7e-65 yagE E amino acid
HLDHABGM_00498 8.4e-128 yagE E Amino acid permease
HLDHABGM_00499 4.3e-86 3.4.21.96 S SLAP domain
HLDHABGM_00500 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLDHABGM_00501 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLDHABGM_00502 1.2e-107 hlyIII S protein, hemolysin III
HLDHABGM_00503 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
HLDHABGM_00504 7.1e-36 yozE S Belongs to the UPF0346 family
HLDHABGM_00505 1.1e-66 yjcE P NhaP-type Na H and K H
HLDHABGM_00506 1.5e-40 yjcE P Sodium proton antiporter
HLDHABGM_00507 1.9e-94 yjcE P Sodium proton antiporter
HLDHABGM_00508 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLDHABGM_00509 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLDHABGM_00510 5.8e-152 dprA LU DNA protecting protein DprA
HLDHABGM_00511 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLDHABGM_00512 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLDHABGM_00513 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
HLDHABGM_00514 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLDHABGM_00515 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLDHABGM_00516 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
HLDHABGM_00517 1.4e-86 C Aldo keto reductase
HLDHABGM_00518 3.8e-48 M LysM domain protein
HLDHABGM_00519 2.9e-15 M LysM domain protein
HLDHABGM_00520 3.1e-240 oppA E ABC transporter substrate-binding protein
HLDHABGM_00521 2.1e-308 oppA E ABC transporter substrate-binding protein
HLDHABGM_00522 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLDHABGM_00523 0.0 smc D Required for chromosome condensation and partitioning
HLDHABGM_00524 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLDHABGM_00525 2.5e-288 pipD E Dipeptidase
HLDHABGM_00527 3.4e-23
HLDHABGM_00528 4.1e-133 cysA V ABC transporter, ATP-binding protein
HLDHABGM_00529 0.0 V FtsX-like permease family
HLDHABGM_00530 2.7e-258 yfnA E amino acid
HLDHABGM_00531 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLDHABGM_00532 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLDHABGM_00533 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HLDHABGM_00534 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLDHABGM_00535 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HLDHABGM_00536 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLDHABGM_00537 4.6e-213 S SLAP domain
HLDHABGM_00538 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HLDHABGM_00539 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
HLDHABGM_00540 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLDHABGM_00541 3e-38 ynzC S UPF0291 protein
HLDHABGM_00542 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
HLDHABGM_00543 0.0 mdlA V ABC transporter
HLDHABGM_00544 0.0 mdlB V ABC transporter
HLDHABGM_00545 0.0 pepO 3.4.24.71 O Peptidase family M13
HLDHABGM_00546 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HLDHABGM_00547 2.9e-116 plsC 2.3.1.51 I Acyltransferase
HLDHABGM_00548 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
HLDHABGM_00549 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HLDHABGM_00550 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLDHABGM_00551 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HLDHABGM_00552 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLDHABGM_00553 1.3e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLDHABGM_00554 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
HLDHABGM_00555 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HLDHABGM_00556 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLDHABGM_00557 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLDHABGM_00558 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HLDHABGM_00559 1.4e-196 nusA K Participates in both transcription termination and antitermination
HLDHABGM_00560 8.8e-47 ylxR K Protein of unknown function (DUF448)
HLDHABGM_00561 3.2e-47 rplGA J ribosomal protein
HLDHABGM_00562 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLDHABGM_00563 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLDHABGM_00564 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLDHABGM_00565 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HLDHABGM_00566 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLDHABGM_00567 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLDHABGM_00568 0.0 dnaK O Heat shock 70 kDa protein
HLDHABGM_00569 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLDHABGM_00570 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLDHABGM_00571 1.5e-102 srtA 3.4.22.70 M sortase family
HLDHABGM_00572 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HLDHABGM_00573 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLDHABGM_00574 1.6e-131 I Carboxylesterase family
HLDHABGM_00576 6.4e-111 L Belongs to the 'phage' integrase family
HLDHABGM_00577 5e-08 S Pfam:DUF955
HLDHABGM_00578 3.4e-29 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00579 5.7e-16 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00580 2e-32 K Helix-turn-helix domain
HLDHABGM_00581 1.7e-25 S Domain of unknown function (DUF771)
HLDHABGM_00592 5.7e-11 S Single-strand binding protein family
HLDHABGM_00598 2.3e-21 S SLAP domain
HLDHABGM_00599 1.4e-24 srtA 3.4.22.70 M sortase family
HLDHABGM_00601 7.4e-40 M domain protein
HLDHABGM_00602 7.2e-15 S SLAP domain
HLDHABGM_00603 1e-30 M domain protein
HLDHABGM_00607 4.3e-48 U TraM recognition site of TraD and TraG
HLDHABGM_00608 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
HLDHABGM_00609 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLDHABGM_00610 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HLDHABGM_00611 1.7e-184 G Transmembrane secretion effector
HLDHABGM_00612 6.1e-136 V ABC transporter transmembrane region
HLDHABGM_00613 5.9e-64 L transposase, IS605 OrfB family
HLDHABGM_00614 8.9e-240 L transposase, IS605 OrfB family
HLDHABGM_00615 2.1e-28 S Peptidase propeptide and YPEB domain
HLDHABGM_00616 2.4e-60 ypaA S Protein of unknown function (DUF1304)
HLDHABGM_00617 2.3e-309 oppA3 E ABC transporter, substratebinding protein
HLDHABGM_00618 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLDHABGM_00619 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLDHABGM_00620 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLDHABGM_00621 2.3e-198 oppD P Belongs to the ABC transporter superfamily
HLDHABGM_00622 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HLDHABGM_00623 5.2e-256 pepC 3.4.22.40 E aminopeptidase
HLDHABGM_00624 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
HLDHABGM_00625 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLDHABGM_00626 7.9e-112
HLDHABGM_00628 1.2e-111 E Belongs to the SOS response-associated peptidase family
HLDHABGM_00629 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLDHABGM_00630 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
HLDHABGM_00631 2e-103 S TPM domain
HLDHABGM_00632 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HLDHABGM_00633 1e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HLDHABGM_00634 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLDHABGM_00635 1e-147 tatD L hydrolase, TatD family
HLDHABGM_00636 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLDHABGM_00637 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLDHABGM_00638 4.5e-39 veg S Biofilm formation stimulator VEG
HLDHABGM_00639 1.1e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HLDHABGM_00640 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLDHABGM_00641 2.2e-120 lsa S ABC transporter
HLDHABGM_00642 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLDHABGM_00643 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HLDHABGM_00644 1.3e-284 lsa S ABC transporter
HLDHABGM_00645 2.4e-44
HLDHABGM_00646 1.4e-37 S Putative adhesin
HLDHABGM_00647 3.7e-261 V ABC transporter transmembrane region
HLDHABGM_00648 1.1e-139
HLDHABGM_00649 3.7e-20
HLDHABGM_00650 8.8e-41 clcA P chloride
HLDHABGM_00651 1.6e-60 clcA P chloride
HLDHABGM_00652 4.7e-26 K FCD
HLDHABGM_00653 2.1e-114 3.6.1.27 I Acid phosphatase homologues
HLDHABGM_00654 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HLDHABGM_00655 0.0 uvrA3 L excinuclease ABC, A subunit
HLDHABGM_00656 9.9e-82 C Flavodoxin
HLDHABGM_00657 1.2e-299 I Protein of unknown function (DUF2974)
HLDHABGM_00658 2.1e-194 pbpX1 V Beta-lactamase
HLDHABGM_00659 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLDHABGM_00660 2.7e-216 aspC 2.6.1.1 E Aminotransferase
HLDHABGM_00661 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLDHABGM_00662 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLDHABGM_00663 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLDHABGM_00664 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLDHABGM_00665 1.8e-245 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLDHABGM_00666 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HLDHABGM_00667 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLDHABGM_00668 3.4e-175 yjeM E Amino Acid
HLDHABGM_00669 7.8e-39 yjeM E Amino Acid
HLDHABGM_00670 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
HLDHABGM_00671 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLDHABGM_00672 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLDHABGM_00673 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLDHABGM_00674 1.3e-148
HLDHABGM_00675 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLDHABGM_00676 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLDHABGM_00677 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
HLDHABGM_00678 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
HLDHABGM_00679 0.0 comEC S Competence protein ComEC
HLDHABGM_00680 3.1e-79 comEA L Competence protein ComEA
HLDHABGM_00681 2.4e-187 ylbL T Belongs to the peptidase S16 family
HLDHABGM_00682 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLDHABGM_00683 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HLDHABGM_00684 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HLDHABGM_00685 5.9e-211 ftsW D Belongs to the SEDS family
HLDHABGM_00686 0.0 typA T GTP-binding protein TypA
HLDHABGM_00687 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLDHABGM_00688 3.5e-32 ykzG S Belongs to the UPF0356 family
HLDHABGM_00689 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLDHABGM_00690 0.0 L Plasmid pRiA4b ORF-3-like protein
HLDHABGM_00691 5.5e-148 S cog cog1373
HLDHABGM_00692 0.0 4.2.1.53 S Myosin-crossreactive antigen
HLDHABGM_00693 2e-91 yxdD K Bacterial regulatory proteins, tetR family
HLDHABGM_00694 1.9e-259 emrY EGP Major facilitator Superfamily
HLDHABGM_00696 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HLDHABGM_00697 1.8e-104 3.2.2.20 K acetyltransferase
HLDHABGM_00699 4.3e-226 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDHABGM_00700 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
HLDHABGM_00701 4.1e-21 K Helix-turn-helix domain, rpiR family
HLDHABGM_00702 1.3e-71 K Helix-turn-helix domain, rpiR family
HLDHABGM_00703 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
HLDHABGM_00704 4.9e-111 ybbL S ABC transporter, ATP-binding protein
HLDHABGM_00705 2.3e-168 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HLDHABGM_00706 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDHABGM_00707 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HLDHABGM_00708 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
HLDHABGM_00709 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
HLDHABGM_00710 2.1e-32
HLDHABGM_00711 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HLDHABGM_00712 2.3e-156 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00713 3.9e-298 V ABC transporter transmembrane region
HLDHABGM_00714 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HLDHABGM_00715 1.7e-193 S TerB-C domain
HLDHABGM_00716 1.2e-17
HLDHABGM_00717 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HLDHABGM_00718 2e-70 S Iron-sulphur cluster biosynthesis
HLDHABGM_00719 1.6e-189 ybiR P Citrate transporter
HLDHABGM_00720 5.1e-96 lemA S LemA family
HLDHABGM_00721 8.3e-157 htpX O Belongs to the peptidase M48B family
HLDHABGM_00722 7.9e-174 K helix_turn_helix, arabinose operon control protein
HLDHABGM_00723 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
HLDHABGM_00724 2.8e-77 P Cobalt transport protein
HLDHABGM_00725 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HLDHABGM_00726 3.2e-90 G Peptidase_C39 like family
HLDHABGM_00727 2.8e-162 M NlpC/P60 family
HLDHABGM_00728 8.4e-25 G Peptidase_C39 like family
HLDHABGM_00730 4.7e-19 M MucBP domain
HLDHABGM_00731 5e-152 L Probable transposase
HLDHABGM_00737 2.2e-87
HLDHABGM_00738 1.8e-223 U Psort location Cytoplasmic, score
HLDHABGM_00739 2.6e-84
HLDHABGM_00742 9.7e-31 dnaG L DNA primase activity
HLDHABGM_00746 1.1e-199 L Probable transposase
HLDHABGM_00750 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLDHABGM_00751 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLDHABGM_00752 5.1e-17
HLDHABGM_00753 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLDHABGM_00754 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLDHABGM_00755 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLDHABGM_00756 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HLDHABGM_00757 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HLDHABGM_00758 1.1e-25
HLDHABGM_00759 1.2e-77 K DNA-templated transcription, initiation
HLDHABGM_00760 5.3e-41
HLDHABGM_00762 6e-21 K Putative DNA-binding domain
HLDHABGM_00763 7.6e-239 pyrP F Permease
HLDHABGM_00764 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLDHABGM_00765 9.2e-262 emrY EGP Major facilitator Superfamily
HLDHABGM_00766 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HLDHABGM_00767 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HLDHABGM_00768 2.6e-280 thrC 4.2.3.1 E Threonine synthase
HLDHABGM_00769 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HLDHABGM_00770 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLDHABGM_00771 9.4e-118
HLDHABGM_00772 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLDHABGM_00774 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLDHABGM_00775 1.3e-116 S Peptidase family M23
HLDHABGM_00776 4e-08
HLDHABGM_00777 6.6e-56
HLDHABGM_00778 2.7e-57
HLDHABGM_00779 1.6e-11
HLDHABGM_00780 8.1e-126 S PAS domain
HLDHABGM_00784 6.2e-17 D nuclear chromosome segregation
HLDHABGM_00785 3.7e-53 M Psort location Cellwall, score
HLDHABGM_00786 1.4e-101 ypuA S Protein of unknown function (DUF1002)
HLDHABGM_00787 4.7e-69 3.4.22.70 M sortase family
HLDHABGM_00794 2.9e-86
HLDHABGM_00795 7e-12 ispH 1.17.7.4 J negative regulation of cytoplasmic translation
HLDHABGM_00796 2.4e-21
HLDHABGM_00799 7.7e-50
HLDHABGM_00802 8.9e-113 U TraM recognition site of TraD and TraG
HLDHABGM_00809 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HLDHABGM_00812 3e-21
HLDHABGM_00813 3.7e-83
HLDHABGM_00814 8.2e-31 yozG K Transcriptional regulator
HLDHABGM_00815 2e-23
HLDHABGM_00816 1.7e-67
HLDHABGM_00817 1.1e-164 natA S ABC transporter, ATP-binding protein
HLDHABGM_00818 1.8e-218 natB CP ABC-2 family transporter protein
HLDHABGM_00819 1.8e-136 fruR K DeoR C terminal sensor domain
HLDHABGM_00820 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HLDHABGM_00821 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HLDHABGM_00822 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HLDHABGM_00823 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
HLDHABGM_00824 3.6e-117 fhuC P ABC transporter
HLDHABGM_00825 5e-129 znuB U ABC 3 transport family
HLDHABGM_00826 4.5e-264 lctP C L-lactate permease
HLDHABGM_00827 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLDHABGM_00828 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
HLDHABGM_00829 1.2e-11
HLDHABGM_00830 1.6e-25 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00832 5.3e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HLDHABGM_00833 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HLDHABGM_00834 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLDHABGM_00837 1.2e-134 EGP Major facilitator Superfamily
HLDHABGM_00838 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
HLDHABGM_00839 0.0 tetP J elongation factor G
HLDHABGM_00840 3.5e-160 yvgN C Aldo keto reductase
HLDHABGM_00841 2e-155 P CorA-like Mg2+ transporter protein
HLDHABGM_00842 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HLDHABGM_00843 4.9e-174 ABC-SBP S ABC transporter
HLDHABGM_00844 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HLDHABGM_00845 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
HLDHABGM_00846 5.2e-248 G Major Facilitator
HLDHABGM_00847 4.1e-18
HLDHABGM_00848 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HLDHABGM_00849 1.4e-176 K AI-2E family transporter
HLDHABGM_00850 8.6e-97 oppA E ABC transporter substrate-binding protein
HLDHABGM_00851 1.2e-232 oppA E ABC transporter substrate-binding protein
HLDHABGM_00852 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLDHABGM_00853 7.2e-29 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S regulation of response to stimulus
HLDHABGM_00854 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HLDHABGM_00855 2.6e-146 S Putative ABC-transporter type IV
HLDHABGM_00856 1.7e-07 S LPXTG cell wall anchor motif
HLDHABGM_00857 1.5e-42 ybaT E Amino acid permease
HLDHABGM_00858 2e-44 ybaT E Amino acid permease
HLDHABGM_00860 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00861 1.4e-22 S CAAX protease self-immunity
HLDHABGM_00862 1.5e-25 S CAAX protease self-immunity
HLDHABGM_00863 2.5e-75 K Helix-turn-helix domain
HLDHABGM_00864 1.1e-110 K Helix-turn-helix XRE-family like proteins
HLDHABGM_00867 8.8e-29
HLDHABGM_00868 1.3e-141 yfeO P Voltage gated chloride channel
HLDHABGM_00869 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
HLDHABGM_00870 8.1e-87 U TraM recognition site of TraD and TraG
HLDHABGM_00871 2.3e-32 I mechanosensitive ion channel activity
HLDHABGM_00873 8.4e-15
HLDHABGM_00874 2.4e-159 trsE S COG0433 Predicted ATPase
HLDHABGM_00875 9.4e-33 M Peptidase family M23
HLDHABGM_00878 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
HLDHABGM_00881 5.7e-18
HLDHABGM_00882 1.5e-239 G Bacterial extracellular solute-binding protein
HLDHABGM_00883 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HLDHABGM_00884 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
HLDHABGM_00886 0.0 S SLAP domain
HLDHABGM_00887 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HLDHABGM_00888 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
HLDHABGM_00889 3.4e-42 S RloB-like protein
HLDHABGM_00890 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
HLDHABGM_00891 5.7e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
HLDHABGM_00893 3.9e-31 S Domain of unknown function DUF1829
HLDHABGM_00894 1.1e-265
HLDHABGM_00895 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HLDHABGM_00896 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLDHABGM_00897 3.9e-25
HLDHABGM_00898 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HLDHABGM_00899 5.7e-135 ecsA V ABC transporter, ATP-binding protein
HLDHABGM_00900 6.5e-221 ecsB U ABC transporter
HLDHABGM_00901 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLDHABGM_00903 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HLDHABGM_00904 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLDHABGM_00905 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HLDHABGM_00906 6.9e-218 mepA V MATE efflux family protein
HLDHABGM_00907 1.8e-176 S SLAP domain
HLDHABGM_00908 4.4e-283 M Peptidase family M1 domain
HLDHABGM_00909 4.5e-188 S Bacteriocin helveticin-J
HLDHABGM_00910 8e-51 L RelB antitoxin
HLDHABGM_00911 7.4e-105 qmcA O prohibitin homologues
HLDHABGM_00912 3.5e-25 qmcA O prohibitin homologues
HLDHABGM_00913 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLDHABGM_00914 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLDHABGM_00915 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLDHABGM_00916 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLDHABGM_00917 5.1e-251 dnaB L Replication initiation and membrane attachment
HLDHABGM_00918 2.1e-168 dnaI L Primosomal protein DnaI
HLDHABGM_00919 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLDHABGM_00920 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
HLDHABGM_00921 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
HLDHABGM_00922 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
HLDHABGM_00923 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
HLDHABGM_00924 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLDHABGM_00925 7.5e-100 J Acetyltransferase (GNAT) domain
HLDHABGM_00926 1.4e-110 yjbF S SNARE associated Golgi protein
HLDHABGM_00927 2.4e-128 S cog cog1373
HLDHABGM_00928 1.4e-109 yniG EGP Major facilitator Superfamily
HLDHABGM_00929 1.6e-236 L transposase, IS605 OrfB family
HLDHABGM_00930 4.5e-76 yniG EGP Major facilitator Superfamily
HLDHABGM_00931 4.9e-35
HLDHABGM_00933 1.3e-42
HLDHABGM_00934 1.9e-75 M LysM domain
HLDHABGM_00935 0.0 1.3.5.4 C FAD binding domain
HLDHABGM_00936 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HLDHABGM_00937 1.7e-249 yhdP S Transporter associated domain
HLDHABGM_00938 3.9e-119 C nitroreductase
HLDHABGM_00939 2.1e-39
HLDHABGM_00940 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HLDHABGM_00941 1.6e-80
HLDHABGM_00942 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
HLDHABGM_00943 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HLDHABGM_00944 5.4e-147 S hydrolase
HLDHABGM_00945 2e-160 rssA S Phospholipase, patatin family
HLDHABGM_00946 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HLDHABGM_00947 3.1e-136 glcR K DeoR C terminal sensor domain
HLDHABGM_00948 2.5e-59 S Enterocin A Immunity
HLDHABGM_00949 1.2e-154 S hydrolase
HLDHABGM_00950 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
HLDHABGM_00951 9.1e-175 rihB 3.2.2.1 F Nucleoside
HLDHABGM_00952 0.0 kup P Transport of potassium into the cell
HLDHABGM_00953 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLDHABGM_00954 1e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLDHABGM_00955 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
HLDHABGM_00956 1.3e-235 G Bacterial extracellular solute-binding protein
HLDHABGM_00957 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
HLDHABGM_00958 5.6e-86
HLDHABGM_00959 1.1e-164 S Protein of unknown function (DUF2974)
HLDHABGM_00960 4.7e-109 glnP P ABC transporter permease
HLDHABGM_00961 3.7e-90 gluC P ABC transporter permease
HLDHABGM_00962 1.2e-146 glnH ET ABC transporter substrate-binding protein
HLDHABGM_00963 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLDHABGM_00964 3.8e-46 udk 2.7.1.48 F Zeta toxin
HLDHABGM_00965 1e-44 udk 2.7.1.48 F Zeta toxin
HLDHABGM_00966 1e-246 G MFS/sugar transport protein
HLDHABGM_00967 1.6e-100 S ABC-type cobalt transport system, permease component
HLDHABGM_00968 0.0 V ABC transporter transmembrane region
HLDHABGM_00969 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
HLDHABGM_00970 1.4e-80 K Transcriptional regulator, MarR family
HLDHABGM_00971 1.9e-147 glnH ET ABC transporter
HLDHABGM_00972 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HLDHABGM_00973 5.9e-45
HLDHABGM_00974 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLDHABGM_00976 2.1e-45 S PFAM Archaeal ATPase
HLDHABGM_00977 7.3e-74
HLDHABGM_00978 0.0 kup P Transport of potassium into the cell
HLDHABGM_00979 0.0 pepO 3.4.24.71 O Peptidase family M13
HLDHABGM_00980 1.4e-210 yttB EGP Major facilitator Superfamily
HLDHABGM_00981 1.1e-183 scrR K helix_turn _helix lactose operon repressor
HLDHABGM_00982 3.7e-295 scrB 3.2.1.26 GH32 G invertase
HLDHABGM_00983 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HLDHABGM_00984 2.3e-181 M CHAP domain
HLDHABGM_00985 3.5e-75
HLDHABGM_00986 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLDHABGM_00987 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLDHABGM_00988 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLDHABGM_00989 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLDHABGM_00990 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLDHABGM_00991 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLDHABGM_00992 9.6e-41 yajC U Preprotein translocase
HLDHABGM_00993 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLDHABGM_00994 1.7e-215 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLDHABGM_00995 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HLDHABGM_00996 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLDHABGM_00997 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLDHABGM_00998 2e-42 yrzL S Belongs to the UPF0297 family
HLDHABGM_00999 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLDHABGM_01000 1.1e-50 yrzB S Belongs to the UPF0473 family
HLDHABGM_01001 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLDHABGM_01002 3.5e-54 trxA O Belongs to the thioredoxin family
HLDHABGM_01003 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLDHABGM_01004 1.1e-71 yslB S Protein of unknown function (DUF2507)
HLDHABGM_01005 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HLDHABGM_01006 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLDHABGM_01007 7.7e-30 ropB K Helix-turn-helix domain
HLDHABGM_01008 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
HLDHABGM_01009 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLDHABGM_01010 6.3e-201 pbpX V Beta-lactamase
HLDHABGM_01011 2.8e-244 nhaC C Na H antiporter NhaC
HLDHABGM_01012 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
HLDHABGM_01013 2.6e-57
HLDHABGM_01014 4.3e-108 ybhL S Belongs to the BI1 family
HLDHABGM_01015 2.7e-171 yegS 2.7.1.107 G Lipid kinase
HLDHABGM_01016 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLDHABGM_01017 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLDHABGM_01018 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLDHABGM_01019 5.8e-203 camS S sex pheromone
HLDHABGM_01020 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLDHABGM_01021 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HLDHABGM_01022 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HLDHABGM_01024 4.1e-83 ydcK S Belongs to the SprT family
HLDHABGM_01025 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HLDHABGM_01026 3e-257 epsU S Polysaccharide biosynthesis protein
HLDHABGM_01027 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLDHABGM_01028 0.0 pacL 3.6.3.8 P P-type ATPase
HLDHABGM_01029 1.4e-204 tnpB L Putative transposase DNA-binding domain
HLDHABGM_01030 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLDHABGM_01031 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLDHABGM_01032 1.7e-204 csaB M Glycosyl transferases group 1
HLDHABGM_01033 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLDHABGM_01034 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HLDHABGM_01035 4.6e-123 gntR1 K UTRA
HLDHABGM_01036 3.3e-179
HLDHABGM_01037 3.4e-45 oppA2 E ABC transporter, substratebinding protein
HLDHABGM_01038 4.4e-239 oppA2 E ABC transporter, substratebinding protein
HLDHABGM_01041 3.2e-240 npr 1.11.1.1 C NADH oxidase
HLDHABGM_01042 6.6e-11
HLDHABGM_01043 1.3e-22 3.6.4.12 S transposase or invertase
HLDHABGM_01044 6.7e-228 slpX S SLAP domain
HLDHABGM_01045 4.4e-144 K SIS domain
HLDHABGM_01046 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HLDHABGM_01047 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HLDHABGM_01048 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HLDHABGM_01050 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HLDHABGM_01052 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HLDHABGM_01053 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HLDHABGM_01054 2.6e-89 G Histidine phosphatase superfamily (branch 1)
HLDHABGM_01055 1.2e-105 G Phosphoglycerate mutase family
HLDHABGM_01056 4.7e-159 D nuclear chromosome segregation
HLDHABGM_01057 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HLDHABGM_01058 2.3e-23 S Protein of unknown function (DUF2929)
HLDHABGM_01059 0.0 dnaE 2.7.7.7 L DNA polymerase
HLDHABGM_01060 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLDHABGM_01061 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HLDHABGM_01062 1e-167 cvfB S S1 domain
HLDHABGM_01063 2.9e-165 xerD D recombinase XerD
HLDHABGM_01064 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDHABGM_01065 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLDHABGM_01066 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLDHABGM_01067 9e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLDHABGM_01068 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLDHABGM_01069 2.7e-18 M Lysin motif
HLDHABGM_01070 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HLDHABGM_01071 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
HLDHABGM_01072 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HLDHABGM_01073 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLDHABGM_01074 1.4e-75 S Tetratricopeptide repeat protein
HLDHABGM_01075 3.8e-99 S Tetratricopeptide repeat protein
HLDHABGM_01076 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLDHABGM_01077 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
HLDHABGM_01078 1.2e-250 yifK E Amino acid permease
HLDHABGM_01079 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLDHABGM_01080 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLDHABGM_01081 0.0 aha1 P E1-E2 ATPase
HLDHABGM_01082 2.4e-175 F DNA/RNA non-specific endonuclease
HLDHABGM_01083 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
HLDHABGM_01084 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLDHABGM_01085 3.4e-73 metI P ABC transporter permease
HLDHABGM_01086 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLDHABGM_01087 1.9e-261 frdC 1.3.5.4 C FAD binding domain
HLDHABGM_01088 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HLDHABGM_01089 2.1e-247 pepC 3.4.22.40 E Peptidase C1-like family
HLDHABGM_01090 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
HLDHABGM_01091 5.7e-272 P Sodium:sulfate symporter transmembrane region
HLDHABGM_01092 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLDHABGM_01093 2e-52 yaaQ S Cyclic-di-AMP receptor
HLDHABGM_01094 6.3e-154 holB 2.7.7.7 L DNA polymerase III
HLDHABGM_01095 1.8e-59 yabA L Involved in initiation control of chromosome replication
HLDHABGM_01096 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLDHABGM_01097 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
HLDHABGM_01098 2.2e-85 S ECF transporter, substrate-specific component
HLDHABGM_01099 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HLDHABGM_01100 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HLDHABGM_01101 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLDHABGM_01102 1.9e-245 L Transposase IS66 family
HLDHABGM_01103 8.7e-34 S Transposase C of IS166 homeodomain
HLDHABGM_01104 9.3e-64 L PFAM IS66 Orf2 family protein
HLDHABGM_01105 7.7e-22
HLDHABGM_01106 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HLDHABGM_01107 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HLDHABGM_01108 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HLDHABGM_01109 0.0 uup S ABC transporter, ATP-binding protein
HLDHABGM_01110 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLDHABGM_01111 1.5e-102 GM NmrA-like family
HLDHABGM_01112 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLDHABGM_01113 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLDHABGM_01114 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLDHABGM_01115 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLDHABGM_01116 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HLDHABGM_01117 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLDHABGM_01118 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HLDHABGM_01119 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HLDHABGM_01120 3.7e-250 lctP C L-lactate permease
HLDHABGM_01121 3.1e-148 glcU U sugar transport
HLDHABGM_01122 7.1e-46
HLDHABGM_01123 2.9e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HLDHABGM_01124 4.3e-24 S SLAP domain
HLDHABGM_01125 7.6e-25 S SLAP domain
HLDHABGM_01128 2.4e-36
HLDHABGM_01129 4.9e-58 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HLDHABGM_01130 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HLDHABGM_01131 0.0 copA 3.6.3.54 P P-type ATPase
HLDHABGM_01132 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HLDHABGM_01133 1e-104
HLDHABGM_01134 1.4e-52 EGP Sugar (and other) transporter
HLDHABGM_01135 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HLDHABGM_01136 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
HLDHABGM_01137 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HLDHABGM_01138 1.7e-284 E Amino acid permease
HLDHABGM_01139 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HLDHABGM_01140 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
HLDHABGM_01141 1.4e-115 mmuP E amino acid
HLDHABGM_01142 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HLDHABGM_01143 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLDHABGM_01144 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLDHABGM_01145 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
HLDHABGM_01146 1.4e-98 L Helix-turn-helix domain
HLDHABGM_01147 1.2e-16
HLDHABGM_01148 4.4e-138 2.7.13.3 T GHKL domain
HLDHABGM_01149 1.2e-127 K LytTr DNA-binding domain
HLDHABGM_01150 6.1e-269 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLDHABGM_01151 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HLDHABGM_01152 9e-98
HLDHABGM_01153 4.9e-108 K LysR substrate binding domain
HLDHABGM_01154 1e-20
HLDHABGM_01155 2.3e-215 S Sterol carrier protein domain
HLDHABGM_01156 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HLDHABGM_01157 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
HLDHABGM_01158 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLDHABGM_01159 8.8e-234 arcA 3.5.3.6 E Arginine
HLDHABGM_01160 9e-137 lysR5 K LysR substrate binding domain
HLDHABGM_01161 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HLDHABGM_01162 1e-48 S Metal binding domain of Ada
HLDHABGM_01163 1e-20 S Enterocin A Immunity
HLDHABGM_01165 5.7e-43 2.4.1.33 V HlyD family secretion protein
HLDHABGM_01166 9.9e-285 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLDHABGM_01167 1.4e-34
HLDHABGM_01168 3.6e-63
HLDHABGM_01171 4.9e-118
HLDHABGM_01172 3.8e-104 pncA Q Isochorismatase family
HLDHABGM_01174 2e-35
HLDHABGM_01175 0.0 snf 2.7.11.1 KL domain protein
HLDHABGM_01176 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLDHABGM_01177 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLDHABGM_01178 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLDHABGM_01179 2.1e-255 S Archaea bacterial proteins of unknown function
HLDHABGM_01180 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HLDHABGM_01181 1.7e-212 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HLDHABGM_01182 1.8e-40 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HLDHABGM_01183 1e-24
HLDHABGM_01184 9.5e-26
HLDHABGM_01185 2.5e-33
HLDHABGM_01186 1.4e-53 S Enterocin A Immunity
HLDHABGM_01187 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HLDHABGM_01188 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLDHABGM_01189 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HLDHABGM_01190 9.6e-121 K response regulator
HLDHABGM_01192 0.0 V ABC transporter
HLDHABGM_01193 4.2e-144 V ABC transporter, ATP-binding protein
HLDHABGM_01194 1.2e-145 V ABC transporter, ATP-binding protein
HLDHABGM_01195 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
HLDHABGM_01196 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLDHABGM_01197 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
HLDHABGM_01198 1.5e-153 spo0J K Belongs to the ParB family
HLDHABGM_01199 3.4e-138 soj D Sporulation initiation inhibitor
HLDHABGM_01200 5e-148 noc K Belongs to the ParB family
HLDHABGM_01201 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HLDHABGM_01202 4e-57 K Helix-turn-helix domain
HLDHABGM_01203 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLDHABGM_01204 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HLDHABGM_01205 5.6e-183 K Transcriptional regulator
HLDHABGM_01206 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
HLDHABGM_01207 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HLDHABGM_01208 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HLDHABGM_01209 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HLDHABGM_01210 1.2e-161 phnD P Phosphonate ABC transporter
HLDHABGM_01212 8.8e-84 uspA T universal stress protein
HLDHABGM_01213 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HLDHABGM_01214 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLDHABGM_01215 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HLDHABGM_01216 7.2e-56 yheA S Belongs to the UPF0342 family
HLDHABGM_01217 1e-226 yhaO L Ser Thr phosphatase family protein
HLDHABGM_01218 0.0 L AAA domain
HLDHABGM_01219 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLDHABGM_01220 2.9e-23
HLDHABGM_01222 2.6e-138 S TerB-C domain
HLDHABGM_01223 1.4e-245 P P-loop Domain of unknown function (DUF2791)
HLDHABGM_01224 0.0 lhr L DEAD DEAH box helicase
HLDHABGM_01225 1.4e-60
HLDHABGM_01226 4.3e-228 amtB P ammonium transporter
HLDHABGM_01227 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HLDHABGM_01229 6.2e-59 psiE S Phosphate-starvation-inducible E
HLDHABGM_01230 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
HLDHABGM_01231 2.9e-69 S Iron-sulphur cluster biosynthesis
HLDHABGM_01233 2.3e-30
HLDHABGM_01234 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HLDHABGM_01235 6.2e-12
HLDHABGM_01236 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDHABGM_01237 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDHABGM_01238 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDHABGM_01239 5.8e-78 M LysM domain protein
HLDHABGM_01240 1.5e-152
HLDHABGM_01241 3e-24
HLDHABGM_01242 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
HLDHABGM_01243 3.4e-79
HLDHABGM_01244 1e-242 cpdA S Calcineurin-like phosphoesterase
HLDHABGM_01245 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HLDHABGM_01246 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLDHABGM_01247 1e-107 ypsA S Belongs to the UPF0398 family
HLDHABGM_01248 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLDHABGM_01249 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HLDHABGM_01250 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLDHABGM_01251 1.3e-114 dnaD L DnaD domain protein
HLDHABGM_01252 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HLDHABGM_01253 9.2e-89 ypmB S Protein conserved in bacteria
HLDHABGM_01254 3e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLDHABGM_01255 9.2e-14
HLDHABGM_01256 3.2e-99 M Glycosyl hydrolases family 25
HLDHABGM_01257 1.3e-29 sip M LysM domain protein
HLDHABGM_01261 1.4e-18 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLDHABGM_01264 5e-38 L Protein of unknown function (DUF3991)
HLDHABGM_01267 8.2e-77 L Integrase
HLDHABGM_01269 5.9e-46
HLDHABGM_01270 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDHABGM_01271 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLDHABGM_01272 2.2e-292 I Acyltransferase
HLDHABGM_01273 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLDHABGM_01274 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLDHABGM_01275 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
HLDHABGM_01276 4.7e-25 S Protein conserved in bacteria
HLDHABGM_01277 3.9e-57
HLDHABGM_01278 4.7e-85
HLDHABGM_01279 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
HLDHABGM_01280 5.8e-186 XK27_05540 S DUF218 domain
HLDHABGM_01281 1.1e-110
HLDHABGM_01282 4.3e-107
HLDHABGM_01283 1.2e-139 yicL EG EamA-like transporter family
HLDHABGM_01284 5e-165 EG EamA-like transporter family
HLDHABGM_01285 6.2e-163 EG EamA-like transporter family
HLDHABGM_01286 2e-32
HLDHABGM_01287 7.8e-38
HLDHABGM_01288 2.6e-155
HLDHABGM_01291 1.8e-81 M NlpC/P60 family
HLDHABGM_01292 2.1e-131 cobQ S glutamine amidotransferase
HLDHABGM_01293 6.5e-64 L RelB antitoxin
HLDHABGM_01294 1.1e-75 V ABC transporter transmembrane region
HLDHABGM_01295 3.8e-15 S Domain of Unknown Function with PDB structure (DUF3850)
HLDHABGM_01297 2.9e-12
HLDHABGM_01298 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLDHABGM_01299 1e-205 M Glycosyl hydrolases family 25
HLDHABGM_01300 2.8e-157 cinI S Serine hydrolase (FSH1)
HLDHABGM_01301 4.3e-298 S Predicted membrane protein (DUF2207)
HLDHABGM_01302 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HLDHABGM_01304 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
HLDHABGM_01305 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLDHABGM_01306 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HLDHABGM_01307 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HLDHABGM_01308 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HLDHABGM_01309 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLDHABGM_01310 3.4e-71 yqhY S Asp23 family, cell envelope-related function
HLDHABGM_01311 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLDHABGM_01312 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLDHABGM_01313 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLDHABGM_01314 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLDHABGM_01315 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLDHABGM_01316 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HLDHABGM_01317 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
HLDHABGM_01318 1.1e-77 6.3.3.2 S ASCH
HLDHABGM_01319 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HLDHABGM_01320 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLDHABGM_01321 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLDHABGM_01322 2.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLDHABGM_01323 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLDHABGM_01324 1.1e-138 stp 3.1.3.16 T phosphatase
HLDHABGM_01325 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HLDHABGM_01326 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLDHABGM_01327 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HLDHABGM_01328 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HLDHABGM_01329 1.4e-30
HLDHABGM_01330 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HLDHABGM_01331 1.2e-100 treR K UTRA
HLDHABGM_01332 3.3e-283 treB G phosphotransferase system
HLDHABGM_01333 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLDHABGM_01334 1.9e-191 yrvN L AAA C-terminal domain
HLDHABGM_01335 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HLDHABGM_01336 5.9e-37 M domain protein
HLDHABGM_01337 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLDHABGM_01338 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
HLDHABGM_01339 8.5e-60
HLDHABGM_01340 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLDHABGM_01341 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLDHABGM_01342 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HLDHABGM_01343 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLDHABGM_01344 1.2e-222 patA 2.6.1.1 E Aminotransferase
HLDHABGM_01345 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HLDHABGM_01346 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HLDHABGM_01347 6.7e-98 M ErfK YbiS YcfS YnhG
HLDHABGM_01348 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLDHABGM_01349 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HLDHABGM_01351 4.7e-46 pspC KT PspC domain
HLDHABGM_01352 3.3e-237 L COG2963 Transposase and inactivated derivatives
HLDHABGM_01353 1.1e-56 S Protein of unknown function (DUF3290)
HLDHABGM_01354 3e-116 yviA S Protein of unknown function (DUF421)
HLDHABGM_01355 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HLDHABGM_01356 8e-182 dnaQ 2.7.7.7 L EXOIII
HLDHABGM_01357 1.9e-158 endA F DNA RNA non-specific endonuclease
HLDHABGM_01358 1.3e-281 pipD E Dipeptidase
HLDHABGM_01359 1.9e-203 malK P ATPases associated with a variety of cellular activities
HLDHABGM_01360 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
HLDHABGM_01361 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HLDHABGM_01362 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HLDHABGM_01363 2.3e-240 G Bacterial extracellular solute-binding protein
HLDHABGM_01364 1.8e-154 corA P CorA-like Mg2+ transporter protein
HLDHABGM_01365 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
HLDHABGM_01366 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
HLDHABGM_01367 0.0 ydgH S MMPL family
HLDHABGM_01369 7.8e-26 K Acetyltransferase (GNAT) domain
HLDHABGM_01370 1.8e-163
HLDHABGM_01371 1.4e-118 D Alpha beta
HLDHABGM_01372 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLDHABGM_01373 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HLDHABGM_01374 1.6e-85
HLDHABGM_01375 2.7e-74
HLDHABGM_01376 1.4e-140 hlyX S Transporter associated domain
HLDHABGM_01377 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLDHABGM_01378 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
HLDHABGM_01379 0.0 clpE O Belongs to the ClpA ClpB family
HLDHABGM_01381 8.9e-224 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLDHABGM_01382 1.2e-185 dltB M MBOAT, membrane-bound O-acyltransferase family
HLDHABGM_01383 1.4e-236 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDHABGM_01385 8.5e-24 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDHABGM_01386 1.1e-66
HLDHABGM_01388 4.5e-189 ydaM M Glycosyl transferase
HLDHABGM_01389 4e-177 G Glycosyl hydrolases family 8
HLDHABGM_01390 1e-119 yfbR S HD containing hydrolase-like enzyme
HLDHABGM_01391 6.4e-159 L HNH nucleases
HLDHABGM_01392 7.3e-148 S Protein of unknown function (DUF805)
HLDHABGM_01393 3.4e-135 glnQ E ABC transporter, ATP-binding protein
HLDHABGM_01394 1.3e-290 glnP P ABC transporter permease
HLDHABGM_01395 8.9e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HLDHABGM_01396 5.8e-64 yeaO S Protein of unknown function, DUF488
HLDHABGM_01397 1.3e-124 terC P Integral membrane protein TerC family
HLDHABGM_01398 2.5e-86 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HLDHABGM_01399 8.5e-133 cobB K SIR2 family
HLDHABGM_01400 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HLDHABGM_01401 9e-144 2.4.2.3 F Phosphorylase superfamily
HLDHABGM_01402 1.9e-138 2.4.2.3 F Phosphorylase superfamily
HLDHABGM_01403 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDHABGM_01404 1.1e-243 yfnA E Amino Acid
HLDHABGM_01405 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
HLDHABGM_01406 8.7e-139 S cog cog1373
HLDHABGM_01407 9.7e-146 S haloacid dehalogenase-like hydrolase
HLDHABGM_01408 2.5e-226 pbuG S permease
HLDHABGM_01410 2.5e-63 rbtT P Major Facilitator Superfamily
HLDHABGM_01411 4.2e-63 lmrB EGP Major facilitator Superfamily
HLDHABGM_01412 8.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLDHABGM_01413 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
HLDHABGM_01414 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
HLDHABGM_01415 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
HLDHABGM_01416 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HLDHABGM_01417 3.8e-115 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HLDHABGM_01418 3.3e-61 3.6.1.55 F NUDIX domain
HLDHABGM_01419 1e-79 S AAA domain
HLDHABGM_01420 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
HLDHABGM_01421 1.1e-152 ydjP I Alpha/beta hydrolase family
HLDHABGM_01422 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HLDHABGM_01423 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
HLDHABGM_01424 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HLDHABGM_01425 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HLDHABGM_01426 9.3e-72 yeaL S Protein of unknown function (DUF441)
HLDHABGM_01427 3.5e-21
HLDHABGM_01428 3.6e-146 cbiQ P cobalt transport
HLDHABGM_01429 0.0 ykoD P ABC transporter, ATP-binding protein
HLDHABGM_01430 1.5e-95 S UPF0397 protein
HLDHABGM_01431 2.9e-66 S Domain of unknown function DUF1828
HLDHABGM_01432 5.5e-09
HLDHABGM_01433 1.5e-50
HLDHABGM_01434 2.6e-177 citR K Putative sugar-binding domain
HLDHABGM_01435 6.2e-249 yjjP S Putative threonine/serine exporter
HLDHABGM_01436 7.3e-126 S Alpha/beta hydrolase family
HLDHABGM_01437 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
HLDHABGM_01438 4.4e-140 ypuA S Protein of unknown function (DUF1002)
HLDHABGM_01439 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLDHABGM_01440 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
HLDHABGM_01441 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLDHABGM_01442 9.3e-86
HLDHABGM_01443 6.9e-47 mdtG EGP Major facilitator Superfamily
HLDHABGM_01444 1.7e-152 mdtG EGP Major facilitator Superfamily
HLDHABGM_01445 1.3e-174
HLDHABGM_01446 2.8e-47 lysM M LysM domain
HLDHABGM_01447 0.0 pepN 3.4.11.2 E aminopeptidase
HLDHABGM_01448 1.3e-250 dtpT U amino acid peptide transporter
HLDHABGM_01449 1.2e-18 S Sugar efflux transporter for intercellular exchange
HLDHABGM_01450 6.6e-70 XK27_02470 K LytTr DNA-binding domain
HLDHABGM_01451 7.9e-92 liaI S membrane
HLDHABGM_01452 4e-16
HLDHABGM_01453 3.9e-186 S Putative peptidoglycan binding domain
HLDHABGM_01454 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
HLDHABGM_01455 9e-121
HLDHABGM_01456 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
HLDHABGM_01457 2e-157 S reductase
HLDHABGM_01458 9.3e-35
HLDHABGM_01459 4.4e-103 K Putative DNA-binding domain
HLDHABGM_01460 6.4e-243 cydA 1.10.3.14 C ubiquinol oxidase
HLDHABGM_01461 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HLDHABGM_01462 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLDHABGM_01463 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLDHABGM_01464 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLDHABGM_01465 9.7e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLDHABGM_01466 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HLDHABGM_01467 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
HLDHABGM_01468 6.2e-43 1.3.5.4 C FAD binding domain
HLDHABGM_01469 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HLDHABGM_01470 2.8e-168 K LysR substrate binding domain
HLDHABGM_01471 1.1e-121 3.6.1.27 I Acid phosphatase homologues
HLDHABGM_01472 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLDHABGM_01473 4.7e-275 ytgP S Polysaccharide biosynthesis protein
HLDHABGM_01474 1.4e-191 oppA E ABC transporter, substratebinding protein
HLDHABGM_01475 1.3e-30
HLDHABGM_01476 1.2e-144 pstS P Phosphate
HLDHABGM_01477 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HLDHABGM_01478 1.2e-152 pstA P Phosphate transport system permease protein PstA
HLDHABGM_01479 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLDHABGM_01480 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
HLDHABGM_01481 9.5e-121 T Transcriptional regulatory protein, C terminal
HLDHABGM_01482 1.1e-282 phoR 2.7.13.3 T Histidine kinase
HLDHABGM_01483 8.9e-133 L Phage integrase family
HLDHABGM_01484 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HLDHABGM_01485 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLDHABGM_01486 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLDHABGM_01487 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDHABGM_01488 1e-156 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDHABGM_01489 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDHABGM_01490 1.4e-60 rplQ J Ribosomal protein L17
HLDHABGM_01491 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDHABGM_01492 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLDHABGM_01493 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLDHABGM_01494 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HLDHABGM_01495 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLDHABGM_01496 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLDHABGM_01497 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLDHABGM_01498 2.6e-71 rplO J Binds to the 23S rRNA
HLDHABGM_01499 2.3e-24 rpmD J Ribosomal protein L30
HLDHABGM_01500 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLDHABGM_01501 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLDHABGM_01502 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLDHABGM_01503 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLDHABGM_01504 6.8e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLDHABGM_01505 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLDHABGM_01506 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLDHABGM_01507 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLDHABGM_01508 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLDHABGM_01509 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HLDHABGM_01510 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLDHABGM_01511 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLDHABGM_01512 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLDHABGM_01513 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLDHABGM_01514 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLDHABGM_01515 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLDHABGM_01516 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
HLDHABGM_01517 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLDHABGM_01518 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HLDHABGM_01519 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLDHABGM_01520 1.8e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLDHABGM_01521 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLDHABGM_01522 8.1e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HLDHABGM_01523 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDHABGM_01524 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDHABGM_01525 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLDHABGM_01526 0.0 S SH3-like domain
HLDHABGM_01527 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLDHABGM_01528 2.1e-171 whiA K May be required for sporulation
HLDHABGM_01529 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HLDHABGM_01530 6.2e-165 rapZ S Displays ATPase and GTPase activities
HLDHABGM_01531 4.1e-90 S Short repeat of unknown function (DUF308)
HLDHABGM_01532 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLDHABGM_01533 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLDHABGM_01534 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLDHABGM_01535 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLDHABGM_01536 8.9e-75 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HLDHABGM_01537 3.5e-70 yebR 1.8.4.14 T GAF domain-containing protein
HLDHABGM_01539 1.6e-08
HLDHABGM_01540 1.4e-83 K FR47-like protein
HLDHABGM_01541 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HLDHABGM_01542 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLDHABGM_01543 2.2e-165 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLDHABGM_01544 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLDHABGM_01545 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLDHABGM_01546 1.8e-62 yabR J S1 RNA binding domain
HLDHABGM_01547 6.8e-60 divIC D Septum formation initiator
HLDHABGM_01548 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HLDHABGM_01549 1.5e-56 asp S Asp23 family, cell envelope-related function
HLDHABGM_01550 7.6e-305 yloV S DAK2 domain fusion protein YloV
HLDHABGM_01551 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLDHABGM_01552 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLDHABGM_01553 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLDHABGM_01554 3.1e-192 oppD P Belongs to the ABC transporter superfamily
HLDHABGM_01555 1.5e-170 oppF P Belongs to the ABC transporter superfamily
HLDHABGM_01556 2.6e-172 oppB P ABC transporter permease
HLDHABGM_01557 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
HLDHABGM_01558 9.7e-46 oppA E ABC transporter substrate-binding protein
HLDHABGM_01559 3.5e-111 G phosphoglycerate mutase
HLDHABGM_01560 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
HLDHABGM_01561 2.1e-175 hrtB V ABC transporter permease
HLDHABGM_01562 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HLDHABGM_01563 1.3e-273 pipD E Dipeptidase
HLDHABGM_01564 2.2e-22
HLDHABGM_01565 3.3e-140 repB EP Plasmid replication protein
HLDHABGM_01566 2.2e-78 S helix_turn_helix, Deoxyribose operon repressor
HLDHABGM_01567 8.1e-175 ulaG S Beta-lactamase superfamily domain
HLDHABGM_01568 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLDHABGM_01569 5.3e-233 ulaA S PTS system sugar-specific permease component
HLDHABGM_01570 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HLDHABGM_01571 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HLDHABGM_01572 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HLDHABGM_01573 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HLDHABGM_01574 5.2e-68 L haloacid dehalogenase-like hydrolase
HLDHABGM_01575 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLDHABGM_01576 3.5e-175 S Cysteine-rich secretory protein family
HLDHABGM_01577 1.6e-41
HLDHABGM_01578 2.6e-118 M NlpC/P60 family
HLDHABGM_01579 1.4e-136 M NlpC P60 family protein
HLDHABGM_01580 5e-88 M NlpC/P60 family
HLDHABGM_01581 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
HLDHABGM_01582 3.9e-42
HLDHABGM_01583 2.9e-279 S O-antigen ligase like membrane protein
HLDHABGM_01584 3.3e-112
HLDHABGM_01585 4.7e-221 tnpB L Putative transposase DNA-binding domain
HLDHABGM_01586 5.5e-77 nrdI F NrdI Flavodoxin like
HLDHABGM_01587 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLDHABGM_01588 2.5e-68
HLDHABGM_01589 9.1e-112 yvpB S Peptidase_C39 like family
HLDHABGM_01590 1.1e-83 S Threonine/Serine exporter, ThrE
HLDHABGM_01591 2.4e-136 thrE S Putative threonine/serine exporter
HLDHABGM_01592 8.9e-292 S ABC transporter
HLDHABGM_01593 8.3e-58
HLDHABGM_01594 5e-72 rimL J Acetyltransferase (GNAT) domain
HLDHABGM_01595 1.4e-34
HLDHABGM_01596 1.2e-30
HLDHABGM_01597 1.8e-111 S Protein of unknown function (DUF554)
HLDHABGM_01598 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HLDHABGM_01599 0.0 pepF E oligoendopeptidase F
HLDHABGM_01600 2.9e-31
HLDHABGM_01601 1.3e-69 doc S Prophage maintenance system killer protein
HLDHABGM_01604 4.6e-27 S Enterocin A Immunity
HLDHABGM_01605 1.7e-22 blpT
HLDHABGM_01606 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLDHABGM_01607 1.6e-161 htrA 3.4.21.107 O serine protease
HLDHABGM_01608 4.1e-147 vicX 3.1.26.11 S domain protein
HLDHABGM_01609 3.4e-149 yycI S YycH protein
HLDHABGM_01610 1.6e-257 yycH S YycH protein
HLDHABGM_01611 2.2e-305 vicK 2.7.13.3 T Histidine kinase
HLDHABGM_01612 4.8e-131 K response regulator
HLDHABGM_01614 4.9e-34
HLDHABGM_01616 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
HLDHABGM_01617 5e-156 arbx M Glycosyl transferase family 8
HLDHABGM_01618 5e-184 arbY M Glycosyl transferase family 8
HLDHABGM_01619 1.6e-182 arbY M Glycosyl transferase family 8
HLDHABGM_01620 6e-168 arbZ I Phosphate acyltransferases
HLDHABGM_01621 1.4e-36 S Cytochrome B5
HLDHABGM_01622 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
HLDHABGM_01623 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HLDHABGM_01624 1.2e-210 S Bacterial protein of unknown function (DUF871)
HLDHABGM_01626 2.3e-43 ybhL S Belongs to the BI1 family
HLDHABGM_01627 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLDHABGM_01629 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDHABGM_01630 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
HLDHABGM_01631 1.3e-61 M Glycosyl hydrolases family 25
HLDHABGM_01632 2.6e-61 M Glycosyl hydrolases family 25
HLDHABGM_01633 3.4e-27
HLDHABGM_01634 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HLDHABGM_01635 5.4e-53 hipB K sequence-specific DNA binding
HLDHABGM_01636 4.8e-42 S SnoaL-like domain
HLDHABGM_01637 0.0 L PLD-like domain
HLDHABGM_01638 3e-246 brnQ U Component of the transport system for branched-chain amino acids
HLDHABGM_01639 2.8e-119 3.6.1.55 F NUDIX domain
HLDHABGM_01640 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
HLDHABGM_01641 2.7e-83 S Protein of unknown function (DUF1211)
HLDHABGM_01642 6.4e-148 yxeH S hydrolase
HLDHABGM_01643 2.7e-32 S reductase
HLDHABGM_01644 4.4e-39 S reductase
HLDHABGM_01645 4.8e-34 S reductase
HLDHABGM_01646 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLDHABGM_01647 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HLDHABGM_01648 6.8e-116 dedA S SNARE-like domain protein
HLDHABGM_01649 3.7e-100 S Protein of unknown function (DUF1461)
HLDHABGM_01650 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLDHABGM_01651 2.1e-92 yutD S Protein of unknown function (DUF1027)
HLDHABGM_01652 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HLDHABGM_01653 4.3e-55
HLDHABGM_01654 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HLDHABGM_01655 3.2e-181 ccpA K catabolite control protein A
HLDHABGM_01656 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HLDHABGM_01657 1.3e-36
HLDHABGM_01658 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLDHABGM_01659 3.7e-146 ykuT M mechanosensitive ion channel
HLDHABGM_01660 6.9e-100 V ATPases associated with a variety of cellular activities
HLDHABGM_01661 1.7e-139
HLDHABGM_01662 5.4e-113
HLDHABGM_01663 1.8e-20
HLDHABGM_01664 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLDHABGM_01665 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLDHABGM_01666 1.7e-29 secG U Preprotein translocase
HLDHABGM_01667 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLDHABGM_01668 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLDHABGM_01669 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
HLDHABGM_01670 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HLDHABGM_01677 3.9e-33 I Carboxylesterase family
HLDHABGM_01678 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HLDHABGM_01679 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
HLDHABGM_01680 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
HLDHABGM_01681 1.7e-148 S haloacid dehalogenase-like hydrolase
HLDHABGM_01682 7e-50
HLDHABGM_01683 1.9e-37
HLDHABGM_01684 1.2e-63 S Alpha beta hydrolase
HLDHABGM_01685 1e-23 S Alpha beta hydrolase
HLDHABGM_01686 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLDHABGM_01687 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLDHABGM_01688 5.1e-226 N Uncharacterized conserved protein (DUF2075)
HLDHABGM_01689 4.8e-205 pbpX1 V Beta-lactamase
HLDHABGM_01690 0.0 L Helicase C-terminal domain protein
HLDHABGM_01691 1.3e-273 E amino acid
HLDHABGM_01692 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HLDHABGM_01695 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDHABGM_01696 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLDHABGM_01697 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HLDHABGM_01698 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HLDHABGM_01699 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLDHABGM_01700 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HLDHABGM_01701 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HLDHABGM_01702 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLDHABGM_01703 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLDHABGM_01704 2.9e-107 IQ reductase
HLDHABGM_01705 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HLDHABGM_01706 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLDHABGM_01707 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLDHABGM_01708 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLDHABGM_01709 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HLDHABGM_01710 1.6e-73 marR K Transcriptional regulator, MarR family
HLDHABGM_01712 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HLDHABGM_01713 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HLDHABGM_01714 2.6e-214 yubA S AI-2E family transporter
HLDHABGM_01715 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLDHABGM_01716 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
HLDHABGM_01717 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HLDHABGM_01718 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HLDHABGM_01719 1.9e-236 S Peptidase M16
HLDHABGM_01720 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HLDHABGM_01721 5.2e-97 ymfM S Helix-turn-helix domain
HLDHABGM_01722 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLDHABGM_01723 8.5e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLDHABGM_01724 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
HLDHABGM_01725 1.9e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
HLDHABGM_01726 2.5e-118 yvyE 3.4.13.9 S YigZ family
HLDHABGM_01727 4.7e-246 comFA L Helicase C-terminal domain protein
HLDHABGM_01728 9.4e-132 comFC S Competence protein
HLDHABGM_01729 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLDHABGM_01730 3.3e-275 yjeM E Amino Acid
HLDHABGM_01731 5.8e-83 S Fic/DOC family
HLDHABGM_01732 9.9e-180
HLDHABGM_01733 3.1e-93
HLDHABGM_01734 2.5e-71
HLDHABGM_01735 2.2e-85 S Protein of unknown function (DUF805)
HLDHABGM_01736 2.3e-69 O OsmC-like protein
HLDHABGM_01737 1.4e-207 EGP Major facilitator Superfamily
HLDHABGM_01738 2.6e-103 sptS 2.7.13.3 T Histidine kinase
HLDHABGM_01739 1.1e-103 sptS 2.7.13.3 T Histidine kinase
HLDHABGM_01740 7e-24 K response regulator
HLDHABGM_01741 4.7e-182 pepA E M42 glutamyl aminopeptidase
HLDHABGM_01742 2.2e-311 ybiT S ABC transporter, ATP-binding protein
HLDHABGM_01743 5.9e-174 S Aldo keto reductase
HLDHABGM_01744 2.7e-138
HLDHABGM_01745 2.8e-202 steT E amino acid
HLDHABGM_01746 2.4e-26 steT E amino acid
HLDHABGM_01747 1.6e-160 steT E amino acid
HLDHABGM_01748 1.2e-188 K Periplasmic binding protein-like domain
HLDHABGM_01749 2e-106 K Transcriptional regulator, AbiEi antitoxin
HLDHABGM_01750 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HLDHABGM_01751 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HLDHABGM_01752 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HLDHABGM_01753 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HLDHABGM_01754 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HLDHABGM_01755 5.4e-165 lacR K Transcriptional regulator
HLDHABGM_01756 8.9e-207 lacS G Transporter
HLDHABGM_01757 5.7e-103 lacS G Transporter
HLDHABGM_01758 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HLDHABGM_01759 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLDHABGM_01760 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HLDHABGM_01761 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HLDHABGM_01763 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLDHABGM_01764 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HLDHABGM_01765 0.0 yjbQ P TrkA C-terminal domain protein
HLDHABGM_01766 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HLDHABGM_01767 7.8e-161 S Oxidoreductase family, NAD-binding Rossmann fold
HLDHABGM_01768 2.1e-130
HLDHABGM_01769 2.1e-116
HLDHABGM_01770 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLDHABGM_01771 1.4e-98 G Aldose 1-epimerase
HLDHABGM_01772 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HLDHABGM_01773 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLDHABGM_01774 0.0 XK27_08315 M Sulfatase
HLDHABGM_01776 4.3e-36
HLDHABGM_01777 6.2e-288 P ABC transporter
HLDHABGM_01778 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
HLDHABGM_01779 1.4e-51
HLDHABGM_01780 2.1e-42
HLDHABGM_01781 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLDHABGM_01782 9.5e-297 ybeC E amino acid
HLDHABGM_01783 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HLDHABGM_01784 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HLDHABGM_01785 2.5e-39 rpmE2 J Ribosomal protein L31
HLDHABGM_01786 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLDHABGM_01787 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLDHABGM_01788 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLDHABGM_01789 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLDHABGM_01790 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HLDHABGM_01791 2.5e-47 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HLDHABGM_01792 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HLDHABGM_01793 9.7e-52 S Iron-sulfur cluster assembly protein
HLDHABGM_01794 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLDHABGM_01795 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HLDHABGM_01796 3e-53 cvpA S Colicin V production protein
HLDHABGM_01798 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLDHABGM_01799 6e-151 3.1.3.48 T Tyrosine phosphatase family
HLDHABGM_01800 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HLDHABGM_01801 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HLDHABGM_01802 2.4e-110 K WHG domain
HLDHABGM_01803 3e-37
HLDHABGM_01804 2.7e-36 yyaR K Acetyltransferase (GNAT) domain
HLDHABGM_01805 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLDHABGM_01806 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HLDHABGM_01807 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLDHABGM_01808 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HLDHABGM_01809 8.6e-199 tnpB L Putative transposase DNA-binding domain
HLDHABGM_01810 4.2e-84 yqeG S HAD phosphatase, family IIIA
HLDHABGM_01811 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
HLDHABGM_01812 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLDHABGM_01813 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HLDHABGM_01814 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLDHABGM_01815 4.6e-216 ylbM S Belongs to the UPF0348 family
HLDHABGM_01816 4.7e-97 yceD S Uncharacterized ACR, COG1399
HLDHABGM_01817 1.2e-126 K response regulator
HLDHABGM_01818 1.3e-277 arlS 2.7.13.3 T Histidine kinase
HLDHABGM_01819 1e-12
HLDHABGM_01820 1.5e-97 S CAAX protease self-immunity
HLDHABGM_01821 6.1e-224 S SLAP domain
HLDHABGM_01822 5.7e-83 S Aminoacyl-tRNA editing domain
HLDHABGM_01823 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLDHABGM_01824 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HLDHABGM_01825 2.2e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLDHABGM_01826 4.5e-58 yodB K Transcriptional regulator, HxlR family
HLDHABGM_01828 8.3e-24 papP P ABC transporter, permease protein
HLDHABGM_01829 9e-20 ywzB S Protein of unknown function (DUF1146)
HLDHABGM_01830 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HLDHABGM_01831 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLDHABGM_01832 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLDHABGM_01833 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLDHABGM_01834 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLDHABGM_01835 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLDHABGM_01836 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HLDHABGM_01837 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLDHABGM_01838 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLDHABGM_01839 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLDHABGM_01840 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLDHABGM_01841 1.3e-113 tdk 2.7.1.21 F thymidine kinase
HLDHABGM_01842 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HLDHABGM_01845 3.9e-195 ampC V Beta-lactamase
HLDHABGM_01846 3.8e-217 EGP Major facilitator Superfamily
HLDHABGM_01847 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HLDHABGM_01848 3.8e-105 vanZ V VanZ like family
HLDHABGM_01849 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLDHABGM_01850 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
HLDHABGM_01851 2.9e-128 K Transcriptional regulatory protein, C terminal
HLDHABGM_01852 7.7e-67 S SdpI/YhfL protein family
HLDHABGM_01853 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
HLDHABGM_01854 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
HLDHABGM_01855 2.5e-89 M Protein of unknown function (DUF3737)
HLDHABGM_01857 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLDHABGM_01858 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HLDHABGM_01859 1.6e-21
HLDHABGM_01860 3.8e-77 comGF U Putative Competence protein ComGF
HLDHABGM_01861 2.3e-41
HLDHABGM_01862 1.8e-69
HLDHABGM_01863 3.1e-43 comGC U competence protein ComGC
HLDHABGM_01864 1.7e-171 comGB NU type II secretion system
HLDHABGM_01865 1.7e-179 comGA NU Type II IV secretion system protein
HLDHABGM_01866 8.9e-133 yebC K Transcriptional regulatory protein
HLDHABGM_01867 7.6e-94 S VanZ like family
HLDHABGM_01868 3.5e-101 ylbE GM NAD(P)H-binding
HLDHABGM_01869 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLDHABGM_01871 1.3e-160 L hmm pf00665
HLDHABGM_01872 5.8e-100 L Helix-turn-helix domain
HLDHABGM_01873 2e-310 E Amino acid permease
HLDHABGM_01875 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLDHABGM_01876 2.2e-90 2.7.7.65 T GGDEF domain
HLDHABGM_01877 8.2e-36
HLDHABGM_01878 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
HLDHABGM_01879 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HLDHABGM_01880 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HLDHABGM_01881 1e-149 D Alpha beta
HLDHABGM_01882 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HLDHABGM_01883 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLDHABGM_01884 7e-142 licT K CAT RNA binding domain
HLDHABGM_01885 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HLDHABGM_01886 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLDHABGM_01887 1.6e-118
HLDHABGM_01888 1.8e-75 K Penicillinase repressor
HLDHABGM_01889 1.4e-147 S hydrolase
HLDHABGM_01890 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLDHABGM_01891 2e-172 ybbR S YbbR-like protein
HLDHABGM_01892 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLDHABGM_01893 7.3e-208 potD P ABC transporter
HLDHABGM_01894 4.8e-127 potC P ABC transporter permease
HLDHABGM_01895 1.3e-129 potB P ABC transporter permease
HLDHABGM_01896 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLDHABGM_01897 2e-163 murB 1.3.1.98 M Cell wall formation
HLDHABGM_01898 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
HLDHABGM_01899 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HLDHABGM_01900 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HLDHABGM_01901 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLDHABGM_01902 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HLDHABGM_01903 1.2e-94
HLDHABGM_01904 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
HLDHABGM_01905 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLDHABGM_01906 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HLDHABGM_01907 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLDHABGM_01908 3.3e-189 cggR K Putative sugar-binding domain
HLDHABGM_01910 2.8e-290
HLDHABGM_01911 4.6e-274 ycaM E amino acid
HLDHABGM_01912 3.1e-139 S Cysteine-rich secretory protein family
HLDHABGM_01913 4.2e-77 K MerR HTH family regulatory protein
HLDHABGM_01914 2.4e-262 lmrB EGP Major facilitator Superfamily
HLDHABGM_01915 3.1e-48 S Domain of unknown function (DUF4811)
HLDHABGM_01916 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLDHABGM_01917 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLDHABGM_01918 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HLDHABGM_01919 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HLDHABGM_01920 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HLDHABGM_01921 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLDHABGM_01922 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLDHABGM_01923 2.3e-56 G Xylose isomerase domain protein TIM barrel
HLDHABGM_01924 8.4e-90 nanK GK ROK family
HLDHABGM_01925 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HLDHABGM_01926 3.7e-66 K Helix-turn-helix domain, rpiR family
HLDHABGM_01927 7.1e-263 E ABC transporter, substratebinding protein
HLDHABGM_01929 1.2e-128 S interspecies interaction between organisms
HLDHABGM_01930 2.7e-34
HLDHABGM_01933 1.9e-21
HLDHABGM_01934 1.7e-147
HLDHABGM_01935 1.5e-169
HLDHABGM_01936 2e-263 glnA 6.3.1.2 E glutamine synthetase
HLDHABGM_01937 7.8e-222 ynbB 4.4.1.1 P aluminum resistance
HLDHABGM_01938 1e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLDHABGM_01939 1.5e-65 yqhL P Rhodanese-like protein
HLDHABGM_01940 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HLDHABGM_01941 3.1e-119 gluP 3.4.21.105 S Rhomboid family
HLDHABGM_01942 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLDHABGM_01943 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HLDHABGM_01944 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HLDHABGM_01945 0.0 S membrane
HLDHABGM_01946 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HLDHABGM_01947 1.3e-38 S RelB antitoxin
HLDHABGM_01948 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HLDHABGM_01949 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLDHABGM_01950 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
HLDHABGM_01951 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDHABGM_01952 8.7e-159 isdE P Periplasmic binding protein
HLDHABGM_01953 6.3e-123 M Iron Transport-associated domain
HLDHABGM_01954 3e-09 isdH M Iron Transport-associated domain
HLDHABGM_01955 8.4e-89
HLDHABGM_01956 6.4e-113 S SLAP domain
HLDHABGM_01957 1.2e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLDHABGM_01958 4.2e-92 S SNARE associated Golgi protein
HLDHABGM_01959 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HLDHABGM_01960 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLDHABGM_01961 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLDHABGM_01962 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HLDHABGM_01963 6.8e-110 yjbK S CYTH
HLDHABGM_01964 4.6e-114 yjbH Q Thioredoxin
HLDHABGM_01965 4e-13 coiA 3.6.4.12 S Competence protein
HLDHABGM_01966 3.3e-132 coiA 3.6.4.12 S Competence protein
HLDHABGM_01967 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLDHABGM_01968 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLDHABGM_01969 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLDHABGM_01970 8.5e-41 ptsH G phosphocarrier protein HPR
HLDHABGM_01971 5.3e-26
HLDHABGM_01972 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HLDHABGM_01973 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HLDHABGM_01974 3e-89 ntd 2.4.2.6 F Nucleoside
HLDHABGM_01975 5.2e-08
HLDHABGM_01976 2e-106 S domain protein
HLDHABGM_01977 2.5e-140 V ABC transporter
HLDHABGM_01978 5.9e-68 S Protein of unknown function (DUF3021)
HLDHABGM_01979 6e-86
HLDHABGM_01980 4.4e-172 S Domain of unknown function (DUF389)
HLDHABGM_01981 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HLDHABGM_01982 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HLDHABGM_01983 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HLDHABGM_01984 3.6e-163 yihY S Belongs to the UPF0761 family
HLDHABGM_01985 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
HLDHABGM_01986 4.1e-80 fld C Flavodoxin
HLDHABGM_01987 7e-87 gtcA S Teichoic acid glycosylation protein
HLDHABGM_01988 1.7e-12 GT2,GT4 M family 8
HLDHABGM_01989 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLDHABGM_01990 4.1e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLDHABGM_01991 3.9e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HLDHABGM_01992 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
HLDHABGM_01993 9e-26
HLDHABGM_01994 6.4e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLDHABGM_01995 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLDHABGM_01996 8.7e-84 2.4.1.58 GT8 M family 8
HLDHABGM_01997 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLDHABGM_01998 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLDHABGM_01999 1.1e-34 S Protein of unknown function (DUF2508)
HLDHABGM_02000 1.5e-36 oppA E ABC transporter substrate-binding protein
HLDHABGM_02002 1.4e-31 O OsmC-like protein
HLDHABGM_02003 1.5e-230 XK27_04775 S PAS domain
HLDHABGM_02004 1.3e-102 S Iron-sulfur cluster assembly protein
HLDHABGM_02005 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLDHABGM_02006 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HLDHABGM_02007 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HLDHABGM_02008 0.0 asnB 6.3.5.4 E Asparagine synthase
HLDHABGM_02009 1.3e-270 S Calcineurin-like phosphoesterase
HLDHABGM_02010 3.9e-84
HLDHABGM_02011 1.6e-105 tag 3.2.2.20 L glycosylase
HLDHABGM_02012 4.5e-168 L COG3385 FOG Transposase and inactivated derivatives
HLDHABGM_02013 1.2e-241 S response to antibiotic
HLDHABGM_02014 4.9e-125
HLDHABGM_02015 0.0 3.6.3.8 P P-type ATPase
HLDHABGM_02016 8.7e-66 2.7.1.191 G PTS system fructose IIA component
HLDHABGM_02017 4.4e-43
HLDHABGM_02018 5.9e-09
HLDHABGM_02019 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
HLDHABGM_02020 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
HLDHABGM_02021 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HLDHABGM_02022 2.1e-78 2.7.13.3 T GHKL domain
HLDHABGM_02023 2.9e-79 K LytTr DNA-binding domain
HLDHABGM_02024 8.7e-30 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLDHABGM_02025 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
HLDHABGM_02026 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
HLDHABGM_02027 2.5e-264 3.6.3.6 P Cation transporter/ATPase, N-terminus
HLDHABGM_02028 1.9e-19
HLDHABGM_02029 2.4e-73 S cog cog1373
HLDHABGM_02030 5.6e-179 S PFAM Archaeal ATPase
HLDHABGM_02031 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
HLDHABGM_02032 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)