ORF_ID e_value Gene_name EC_number CAZy COGs Description
PMLCOEMG_00001 2e-106 S domain protein
PMLCOEMG_00002 2.5e-140 V ABC transporter
PMLCOEMG_00003 5.9e-68 S Protein of unknown function (DUF3021)
PMLCOEMG_00004 6e-86
PMLCOEMG_00005 4.4e-172 S Domain of unknown function (DUF389)
PMLCOEMG_00006 3e-84 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PMLCOEMG_00007 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PMLCOEMG_00008 7.1e-46
PMLCOEMG_00009 3.1e-148 glcU U sugar transport
PMLCOEMG_00010 1.1e-249 lctP C L-lactate permease
PMLCOEMG_00011 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PMLCOEMG_00012 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PMLCOEMG_00013 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PMLCOEMG_00014 5.5e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PMLCOEMG_00015 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PMLCOEMG_00016 7.7e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PMLCOEMG_00017 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PMLCOEMG_00018 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PMLCOEMG_00019 8.5e-133 cobB K SIR2 family
PMLCOEMG_00020 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
PMLCOEMG_00021 1.3e-124 terC P Integral membrane protein TerC family
PMLCOEMG_00022 5.8e-64 yeaO S Protein of unknown function, DUF488
PMLCOEMG_00023 8.9e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PMLCOEMG_00024 1.3e-290 glnP P ABC transporter permease
PMLCOEMG_00025 3.4e-135 glnQ E ABC transporter, ATP-binding protein
PMLCOEMG_00026 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PMLCOEMG_00027 1.6e-161 htrA 3.4.21.107 O serine protease
PMLCOEMG_00028 4.1e-147 vicX 3.1.26.11 S domain protein
PMLCOEMG_00029 2.5e-147 yycI S YycH protein
PMLCOEMG_00030 1.6e-257 yycH S YycH protein
PMLCOEMG_00031 2.2e-305 vicK 2.7.13.3 T Histidine kinase
PMLCOEMG_00032 4.8e-131 K response regulator
PMLCOEMG_00034 4.9e-34
PMLCOEMG_00036 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
PMLCOEMG_00037 5e-156 arbx M Glycosyl transferase family 8
PMLCOEMG_00038 5e-184 arbY M Glycosyl transferase family 8
PMLCOEMG_00039 1.6e-182 arbY M Glycosyl transferase family 8
PMLCOEMG_00040 6e-168 arbZ I Phosphate acyltransferases
PMLCOEMG_00041 1.4e-36 S Cytochrome B5
PMLCOEMG_00042 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
PMLCOEMG_00043 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PMLCOEMG_00044 1.2e-10
PMLCOEMG_00045 2.8e-65 K LytTr DNA-binding domain
PMLCOEMG_00046 1.2e-49 S Protein of unknown function (DUF3021)
PMLCOEMG_00047 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PMLCOEMG_00048 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMLCOEMG_00049 6e-132 S membrane transporter protein
PMLCOEMG_00050 2.2e-125 gpmB G Belongs to the phosphoglycerate mutase family
PMLCOEMG_00051 6.6e-162 czcD P cation diffusion facilitator family transporter
PMLCOEMG_00052 1.4e-23
PMLCOEMG_00053 1.7e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PMLCOEMG_00054 2.4e-183 S AAA domain
PMLCOEMG_00055 7.3e-44
PMLCOEMG_00056 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
PMLCOEMG_00057 4.1e-52
PMLCOEMG_00058 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PMLCOEMG_00059 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PMLCOEMG_00060 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PMLCOEMG_00061 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMLCOEMG_00062 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PMLCOEMG_00063 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMLCOEMG_00064 1.2e-94 sigH K Belongs to the sigma-70 factor family
PMLCOEMG_00065 1.7e-34
PMLCOEMG_00066 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PMLCOEMG_00067 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PMLCOEMG_00068 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PMLCOEMG_00069 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
PMLCOEMG_00070 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PMLCOEMG_00071 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PMLCOEMG_00072 2.8e-157 pstS P Phosphate
PMLCOEMG_00073 2.6e-162 pstC P probably responsible for the translocation of the substrate across the membrane
PMLCOEMG_00074 4.5e-79 S helix_turn_helix, Deoxyribose operon repressor
PMLCOEMG_00075 3.3e-140 repB EP Plasmid replication protein
PMLCOEMG_00076 2.2e-22
PMLCOEMG_00077 1.1e-183 scrR K helix_turn _helix lactose operon repressor
PMLCOEMG_00078 3.7e-295 scrB 3.2.1.26 GH32 G invertase
PMLCOEMG_00079 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
PMLCOEMG_00080 2.3e-181 M CHAP domain
PMLCOEMG_00081 3.5e-75
PMLCOEMG_00082 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PMLCOEMG_00083 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PMLCOEMG_00084 1.7e-22 blpT
PMLCOEMG_00085 4.6e-27 S Enterocin A Immunity
PMLCOEMG_00088 1.3e-69 doc S Prophage maintenance system killer protein
PMLCOEMG_00089 2.9e-31
PMLCOEMG_00090 0.0 pepF E oligoendopeptidase F
PMLCOEMG_00091 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PMLCOEMG_00092 1.8e-111 S Protein of unknown function (DUF554)
PMLCOEMG_00093 1.2e-30
PMLCOEMG_00094 1.4e-34
PMLCOEMG_00095 5e-72 rimL J Acetyltransferase (GNAT) domain
PMLCOEMG_00096 8.3e-58
PMLCOEMG_00097 8.9e-292 S ABC transporter
PMLCOEMG_00098 2.4e-136 thrE S Putative threonine/serine exporter
PMLCOEMG_00099 1.1e-83 S Threonine/Serine exporter, ThrE
PMLCOEMG_00100 9.1e-112 yvpB S Peptidase_C39 like family
PMLCOEMG_00101 2.5e-68
PMLCOEMG_00102 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMLCOEMG_00103 5.5e-77 nrdI F NrdI Flavodoxin like
PMLCOEMG_00104 1.2e-35 XK27_09600 V ABC transporter, ATP-binding protein
PMLCOEMG_00105 3.5e-79 K Transcriptional regulator, MarR family
PMLCOEMG_00106 1.9e-147 glnH ET ABC transporter
PMLCOEMG_00107 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
PMLCOEMG_00108 4.7e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PMLCOEMG_00109 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PMLCOEMG_00110 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PMLCOEMG_00111 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
PMLCOEMG_00112 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
PMLCOEMG_00113 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMLCOEMG_00114 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PMLCOEMG_00115 2.3e-56 G Xylose isomerase domain protein TIM barrel
PMLCOEMG_00116 8.4e-90 nanK GK ROK family
PMLCOEMG_00117 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PMLCOEMG_00118 3.7e-66 K Helix-turn-helix domain, rpiR family
PMLCOEMG_00119 7.1e-263 E ABC transporter, substratebinding protein
PMLCOEMG_00120 9.1e-10 K peptidyl-tyrosine sulfation
PMLCOEMG_00122 1.2e-128 S interspecies interaction between organisms
PMLCOEMG_00123 2.7e-34
PMLCOEMG_00126 1.9e-21
PMLCOEMG_00127 1.7e-147
PMLCOEMG_00128 1.5e-169
PMLCOEMG_00129 2e-263 glnA 6.3.1.2 E glutamine synthetase
PMLCOEMG_00130 7.8e-222 ynbB 4.4.1.1 P aluminum resistance
PMLCOEMG_00131 1e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PMLCOEMG_00132 1.5e-65 yqhL P Rhodanese-like protein
PMLCOEMG_00133 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
PMLCOEMG_00134 3.1e-119 gluP 3.4.21.105 S Rhomboid family
PMLCOEMG_00135 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PMLCOEMG_00136 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PMLCOEMG_00137 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PMLCOEMG_00138 0.0 S membrane
PMLCOEMG_00139 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
PMLCOEMG_00140 1.3e-38 S RelB antitoxin
PMLCOEMG_00141 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
PMLCOEMG_00142 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PMLCOEMG_00143 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
PMLCOEMG_00144 7.3e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMLCOEMG_00145 8.7e-159 isdE P Periplasmic binding protein
PMLCOEMG_00146 6.3e-123 M Iron Transport-associated domain
PMLCOEMG_00147 3e-09 isdH M Iron Transport-associated domain
PMLCOEMG_00148 8.4e-89
PMLCOEMG_00149 6.4e-113 S SLAP domain
PMLCOEMG_00150 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
PMLCOEMG_00151 4.9e-111 ybbL S ABC transporter, ATP-binding protein
PMLCOEMG_00152 0.0 S SH3-like domain
PMLCOEMG_00153 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PMLCOEMG_00154 2.1e-171 whiA K May be required for sporulation
PMLCOEMG_00155 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PMLCOEMG_00156 6.2e-165 rapZ S Displays ATPase and GTPase activities
PMLCOEMG_00157 4.1e-90 S Short repeat of unknown function (DUF308)
PMLCOEMG_00158 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PMLCOEMG_00159 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PMLCOEMG_00160 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PMLCOEMG_00161 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PMLCOEMG_00162 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PMLCOEMG_00163 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PMLCOEMG_00164 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PMLCOEMG_00165 5.1e-17
PMLCOEMG_00166 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PMLCOEMG_00167 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PMLCOEMG_00168 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PMLCOEMG_00169 9.4e-132 comFC S Competence protein
PMLCOEMG_00170 4.7e-246 comFA L Helicase C-terminal domain protein
PMLCOEMG_00171 2.4e-92 V ABC transporter, ATP-binding protein
PMLCOEMG_00172 4.7e-60 S ABC-2 family transporter protein
PMLCOEMG_00173 2.1e-76 S ABC-2 family transporter protein
PMLCOEMG_00174 8.2e-230 pbuG S permease
PMLCOEMG_00175 8.2e-140 cof S haloacid dehalogenase-like hydrolase
PMLCOEMG_00176 9.4e-72
PMLCOEMG_00177 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PMLCOEMG_00178 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PMLCOEMG_00179 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PMLCOEMG_00180 3.7e-159 yeaE S Aldo/keto reductase family
PMLCOEMG_00181 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
PMLCOEMG_00182 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
PMLCOEMG_00183 1.3e-282 xylG 3.6.3.17 S ABC transporter
PMLCOEMG_00184 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
PMLCOEMG_00185 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
PMLCOEMG_00186 2.8e-100 S ECF transporter, substrate-specific component
PMLCOEMG_00187 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PMLCOEMG_00188 0.0 macB_3 V ABC transporter, ATP-binding protein
PMLCOEMG_00189 1.6e-194 S DUF218 domain
PMLCOEMG_00190 2.7e-120 S CAAX protease self-immunity
PMLCOEMG_00191 3e-111 ropB K Transcriptional regulator
PMLCOEMG_00192 4.2e-154 EGP Major facilitator Superfamily
PMLCOEMG_00193 5.4e-51
PMLCOEMG_00194 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00195 4.1e-276 V ABC transporter transmembrane region
PMLCOEMG_00196 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
PMLCOEMG_00197 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PMLCOEMG_00198 2.8e-205 napA P Sodium/hydrogen exchanger family
PMLCOEMG_00199 0.0 cadA P P-type ATPase
PMLCOEMG_00200 1.5e-80 ykuL S (CBS) domain
PMLCOEMG_00201 1e-207 ywhK S Membrane
PMLCOEMG_00202 4.1e-44
PMLCOEMG_00203 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
PMLCOEMG_00204 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PMLCOEMG_00205 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
PMLCOEMG_00206 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PMLCOEMG_00207 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PMLCOEMG_00208 7.6e-177 pbpX2 V Beta-lactamase
PMLCOEMG_00209 2.3e-133 S Protein of unknown function (DUF975)
PMLCOEMG_00210 2.7e-137 lysA2 M Glycosyl hydrolases family 25
PMLCOEMG_00211 7.9e-291 ytgP S Polysaccharide biosynthesis protein
PMLCOEMG_00212 1.9e-36
PMLCOEMG_00213 0.0 XK27_06780 V ABC transporter permease
PMLCOEMG_00214 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
PMLCOEMG_00215 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLCOEMG_00216 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
PMLCOEMG_00217 0.0 clpE O AAA domain (Cdc48 subfamily)
PMLCOEMG_00218 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PMLCOEMG_00219 2.3e-72 cycA E Amino acid permease
PMLCOEMG_00220 3.4e-142 cycA E Amino acid permease
PMLCOEMG_00221 9.2e-248 yifK E Amino acid permease
PMLCOEMG_00222 6.4e-135 S PFAM Archaeal ATPase
PMLCOEMG_00223 9.8e-166 V HNH endonuclease
PMLCOEMG_00224 4.2e-92 S SNARE associated Golgi protein
PMLCOEMG_00225 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
PMLCOEMG_00226 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PMLCOEMG_00227 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PMLCOEMG_00228 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
PMLCOEMG_00229 6.8e-110 yjbK S CYTH
PMLCOEMG_00230 4.6e-114 yjbH Q Thioredoxin
PMLCOEMG_00231 1.4e-158 coiA 3.6.4.12 S Competence protein
PMLCOEMG_00232 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PMLCOEMG_00233 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PMLCOEMG_00234 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PMLCOEMG_00235 8.5e-41 ptsH G phosphocarrier protein HPR
PMLCOEMG_00236 5.3e-26
PMLCOEMG_00237 7.7e-22 S SLAP domain
PMLCOEMG_00238 1e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PMLCOEMG_00239 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PMLCOEMG_00240 1.1e-25
PMLCOEMG_00241 1.2e-77 K DNA-templated transcription, initiation
PMLCOEMG_00242 5.3e-41
PMLCOEMG_00244 2.4e-73 S cog cog1373
PMLCOEMG_00245 5.6e-179 S PFAM Archaeal ATPase
PMLCOEMG_00246 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
PMLCOEMG_00247 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PMLCOEMG_00248 9.3e-72 yeaL S Protein of unknown function (DUF441)
PMLCOEMG_00249 3.5e-21
PMLCOEMG_00250 3.6e-146 cbiQ P cobalt transport
PMLCOEMG_00251 0.0 ykoD P ABC transporter, ATP-binding protein
PMLCOEMG_00252 1.5e-95 S UPF0397 protein
PMLCOEMG_00253 2.9e-66 S Domain of unknown function DUF1828
PMLCOEMG_00254 5.5e-09
PMLCOEMG_00255 1.5e-50
PMLCOEMG_00256 2.6e-177 citR K Putative sugar-binding domain
PMLCOEMG_00257 3.5e-285 lsa S ABC transporter
PMLCOEMG_00258 6.3e-45
PMLCOEMG_00259 3.4e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PMLCOEMG_00260 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PMLCOEMG_00261 5.7e-52 S Iron-sulfur cluster assembly protein
PMLCOEMG_00262 1.9e-107 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PMLCOEMG_00263 9e-11 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PMLCOEMG_00264 4.2e-24 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PMLCOEMG_00265 2.9e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PMLCOEMG_00266 2.5e-215 sptS 2.7.13.3 T Histidine kinase
PMLCOEMG_00267 3.6e-208 EGP Major facilitator Superfamily
PMLCOEMG_00268 1.9e-68 O OsmC-like protein
PMLCOEMG_00269 5.7e-94 S Protein of unknown function (DUF805)
PMLCOEMG_00270 6e-76
PMLCOEMG_00271 1.3e-290
PMLCOEMG_00272 8.9e-84 S Fic/DOC family
PMLCOEMG_00273 3.5e-277 yjeM E Amino Acid
PMLCOEMG_00274 3.8e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMLCOEMG_00275 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
PMLCOEMG_00276 4.7e-25 S Protein conserved in bacteria
PMLCOEMG_00277 3.9e-57
PMLCOEMG_00278 4.7e-85
PMLCOEMG_00279 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
PMLCOEMG_00280 9.5e-144 XK27_05540 S DUF218 domain
PMLCOEMG_00281 1.2e-109
PMLCOEMG_00282 3.5e-83
PMLCOEMG_00283 7.3e-83 yicL EG EamA-like transporter family
PMLCOEMG_00284 5.9e-166 EG EamA-like transporter family
PMLCOEMG_00285 3.9e-165 EG EamA-like transporter family
PMLCOEMG_00286 2.3e-36
PMLCOEMG_00287 1.4e-109 yniG EGP Major facilitator Superfamily
PMLCOEMG_00288 2.4e-128 S cog cog1373
PMLCOEMG_00291 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
PMLCOEMG_00292 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
PMLCOEMG_00293 1.8e-230 steT_1 E amino acid
PMLCOEMG_00294 2.2e-139 puuD S peptidase C26
PMLCOEMG_00296 1.5e-152
PMLCOEMG_00297 3e-24
PMLCOEMG_00298 6.8e-60 divIC D Septum formation initiator
PMLCOEMG_00299 1.8e-62 yabR J S1 RNA binding domain
PMLCOEMG_00300 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PMLCOEMG_00301 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMLCOEMG_00302 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PMLCOEMG_00303 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMLCOEMG_00304 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PMLCOEMG_00305 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
PMLCOEMG_00306 6.2e-288 P ABC transporter
PMLCOEMG_00307 4.3e-36
PMLCOEMG_00309 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
PMLCOEMG_00310 2.5e-86 K GNAT family
PMLCOEMG_00311 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
PMLCOEMG_00312 9.8e-123 rbtT P Major Facilitator Superfamily
PMLCOEMG_00313 4.2e-63 lmrB EGP Major facilitator Superfamily
PMLCOEMG_00314 1.2e-250 yifK E Amino acid permease
PMLCOEMG_00315 2.5e-245 V ABC-type multidrug transport system, ATPase and permease components
PMLCOEMG_00316 5.3e-116 P ABC transporter permease
PMLCOEMG_00317 1.5e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLCOEMG_00318 1e-156 cjaA ET ABC transporter substrate-binding protein
PMLCOEMG_00319 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PMLCOEMG_00320 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PMLCOEMG_00321 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PMLCOEMG_00322 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
PMLCOEMG_00323 7.1e-158 metQ1 P Belongs to the nlpA lipoprotein family
PMLCOEMG_00324 1.9e-25
PMLCOEMG_00325 0.0 mco Q Multicopper oxidase
PMLCOEMG_00326 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
PMLCOEMG_00327 0.0 oppA E ABC transporter
PMLCOEMG_00328 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
PMLCOEMG_00329 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
PMLCOEMG_00330 1e-137 S Protein of unknown function (DUF3100)
PMLCOEMG_00331 9.7e-83 S An automated process has identified a potential problem with this gene model
PMLCOEMG_00332 1.8e-40
PMLCOEMG_00333 3.7e-261 V ABC transporter transmembrane region
PMLCOEMG_00334 1.4e-37 S Putative adhesin
PMLCOEMG_00335 1.7e-193 S TerB-C domain
PMLCOEMG_00336 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PMLCOEMG_00337 3.9e-298 V ABC transporter transmembrane region
PMLCOEMG_00338 2.3e-156 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00339 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PMLCOEMG_00340 2.1e-32
PMLCOEMG_00341 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
PMLCOEMG_00342 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
PMLCOEMG_00343 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PMLCOEMG_00344 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLCOEMG_00345 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLCOEMG_00346 0.0 mtlR K Mga helix-turn-helix domain
PMLCOEMG_00347 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PMLCOEMG_00348 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PMLCOEMG_00349 6.8e-243 cycA E Amino acid permease
PMLCOEMG_00350 3.8e-85 maa S transferase hexapeptide repeat
PMLCOEMG_00351 3.3e-158 K Transcriptional regulator
PMLCOEMG_00352 1.1e-62 manO S Domain of unknown function (DUF956)
PMLCOEMG_00353 1e-173 manN G system, mannose fructose sorbose family IID component
PMLCOEMG_00354 1.7e-129 manY G PTS system
PMLCOEMG_00355 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PMLCOEMG_00356 3.1e-71 2.5.1.74 H UbiA prenyltransferase family
PMLCOEMG_00357 7.7e-26
PMLCOEMG_00358 5.7e-84 S PFAM Archaeal ATPase
PMLCOEMG_00359 2.2e-85 S PFAM Archaeal ATPase
PMLCOEMG_00360 8.8e-29
PMLCOEMG_00363 4.9e-111 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00364 2.5e-75 K Helix-turn-helix domain
PMLCOEMG_00365 1.9e-25 S CAAX protease self-immunity
PMLCOEMG_00366 1.4e-22 S CAAX protease self-immunity
PMLCOEMG_00367 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00369 1.6e-96 ybaT E Amino acid permease
PMLCOEMG_00371 1.1e-272 pipD E Dipeptidase
PMLCOEMG_00372 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PMLCOEMG_00373 3.3e-176 hrtB V ABC transporter permease
PMLCOEMG_00374 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
PMLCOEMG_00375 3.5e-111 G phosphoglycerate mutase
PMLCOEMG_00376 4.1e-141 aroD S Alpha/beta hydrolase family
PMLCOEMG_00377 2.2e-142 S Belongs to the UPF0246 family
PMLCOEMG_00378 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PMLCOEMG_00379 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PMLCOEMG_00380 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PMLCOEMG_00381 4e-57 K Helix-turn-helix domain
PMLCOEMG_00382 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMLCOEMG_00383 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
PMLCOEMG_00384 5.6e-183 K Transcriptional regulator
PMLCOEMG_00385 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PMLCOEMG_00386 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PMLCOEMG_00387 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PMLCOEMG_00388 0.0 snf 2.7.11.1 KL domain protein
PMLCOEMG_00389 8.4e-25 G Peptidase_C39 like family
PMLCOEMG_00390 2.8e-162 M NlpC/P60 family
PMLCOEMG_00391 6.5e-91 G Peptidase_C39 like family
PMLCOEMG_00392 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
PMLCOEMG_00393 2.8e-77 P Cobalt transport protein
PMLCOEMG_00394 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
PMLCOEMG_00395 7.9e-174 K helix_turn_helix, arabinose operon control protein
PMLCOEMG_00396 8.3e-157 htpX O Belongs to the peptidase M48B family
PMLCOEMG_00397 5.1e-96 lemA S LemA family
PMLCOEMG_00398 7.5e-192 ybiR P Citrate transporter
PMLCOEMG_00399 2e-70 S Iron-sulphur cluster biosynthesis
PMLCOEMG_00400 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
PMLCOEMG_00401 1.2e-17
PMLCOEMG_00402 1.1e-07 S Uncharacterised protein family (UPF0236)
PMLCOEMG_00403 4.5e-189 ydaM M Glycosyl transferase
PMLCOEMG_00404 4e-177 G Glycosyl hydrolases family 8
PMLCOEMG_00405 1e-119 yfbR S HD containing hydrolase-like enzyme
PMLCOEMG_00406 6.4e-159 L HNH nucleases
PMLCOEMG_00407 3.3e-131 S Protein of unknown function (DUF805)
PMLCOEMG_00408 3.1e-98 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PMLCOEMG_00409 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PMLCOEMG_00410 5.5e-148 S cog cog1373
PMLCOEMG_00411 0.0 4.2.1.53 S Myosin-crossreactive antigen
PMLCOEMG_00412 2.8e-29 yxdD K Bacterial regulatory proteins, tetR family
PMLCOEMG_00413 1.2e-48 yxdD K Bacterial regulatory proteins, tetR family
PMLCOEMG_00414 1.9e-259 emrY EGP Major facilitator Superfamily
PMLCOEMG_00417 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
PMLCOEMG_00418 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
PMLCOEMG_00419 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
PMLCOEMG_00420 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PMLCOEMG_00421 1.9e-153 ydjP I Alpha/beta hydrolase family
PMLCOEMG_00422 5.7e-272 P Sodium:sulfate symporter transmembrane region
PMLCOEMG_00423 5e-133 hxlA 6.2.1.3 H Aldolase/RraA
PMLCOEMG_00424 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
PMLCOEMG_00425 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PMLCOEMG_00426 1.9e-261 frdC 1.3.5.4 C FAD binding domain
PMLCOEMG_00427 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PMLCOEMG_00428 2e-73 metI P ABC transporter permease
PMLCOEMG_00429 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PMLCOEMG_00430 2e-160 metQ2 P Belongs to the nlpA lipoprotein family
PMLCOEMG_00431 1.9e-175 F DNA/RNA non-specific endonuclease
PMLCOEMG_00432 4.4e-239 aha1 P E1-E2 ATPase
PMLCOEMG_00436 1.6e-36
PMLCOEMG_00437 1.1e-08
PMLCOEMG_00438 1.7e-125 Z012_12235 S Baseplate J-like protein
PMLCOEMG_00439 9.5e-33
PMLCOEMG_00440 1.2e-48
PMLCOEMG_00441 5.7e-104
PMLCOEMG_00442 2.1e-46
PMLCOEMG_00443 1.2e-58 M LysM domain
PMLCOEMG_00444 0.0 3.4.14.13 M Phage tail tape measure protein TP901
PMLCOEMG_00446 9e-27
PMLCOEMG_00447 4e-56
PMLCOEMG_00448 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
PMLCOEMG_00449 8e-57
PMLCOEMG_00450 2.9e-45
PMLCOEMG_00451 1.5e-75
PMLCOEMG_00452 2.1e-30 S Protein of unknown function (DUF4054)
PMLCOEMG_00453 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
PMLCOEMG_00454 1.6e-58
PMLCOEMG_00455 1.5e-86 S Uncharacterized protein conserved in bacteria (DUF2213)
PMLCOEMG_00456 1.1e-07 S Lysin motif
PMLCOEMG_00457 1e-97 S Phage Mu protein F like protein
PMLCOEMG_00458 7e-142 S Protein of unknown function (DUF1073)
PMLCOEMG_00459 1.8e-230 S Terminase-like family
PMLCOEMG_00460 3.5e-25 L Terminase small subunit
PMLCOEMG_00461 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
PMLCOEMG_00462 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
PMLCOEMG_00470 1.6e-14
PMLCOEMG_00471 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
PMLCOEMG_00477 1.4e-51 dnaC L IstB-like ATP binding protein
PMLCOEMG_00478 2.3e-33 S Conserved phage C-terminus (Phg_2220_C)
PMLCOEMG_00479 2.4e-59 S Protein of unknown function (DUF1071)
PMLCOEMG_00481 7.7e-48
PMLCOEMG_00483 5e-07 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00484 7.2e-10
PMLCOEMG_00489 5.1e-88 S AntA/AntB antirepressor
PMLCOEMG_00491 2e-20 cro K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00492 2.8e-13 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00494 3e-59
PMLCOEMG_00495 6e-14
PMLCOEMG_00499 3.2e-13
PMLCOEMG_00500 1.6e-147 sip L Belongs to the 'phage' integrase family
PMLCOEMG_00501 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PMLCOEMG_00502 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PMLCOEMG_00503 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PMLCOEMG_00504 1.7e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
PMLCOEMG_00505 7e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PMLCOEMG_00506 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PMLCOEMG_00507 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PMLCOEMG_00508 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
PMLCOEMG_00509 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
PMLCOEMG_00510 9.7e-169
PMLCOEMG_00511 7.5e-143
PMLCOEMG_00512 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PMLCOEMG_00513 1.4e-26
PMLCOEMG_00514 6.7e-145
PMLCOEMG_00515 5.1e-137
PMLCOEMG_00516 4.5e-141
PMLCOEMG_00517 9.6e-124 skfE V ATPases associated with a variety of cellular activities
PMLCOEMG_00518 1.5e-59 yvoA_1 K Transcriptional regulator, GntR family
PMLCOEMG_00519 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PMLCOEMG_00520 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PMLCOEMG_00521 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
PMLCOEMG_00522 4.8e-81 mutT 3.6.1.55 F NUDIX domain
PMLCOEMG_00523 1.4e-127 S Peptidase family M23
PMLCOEMG_00524 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PMLCOEMG_00525 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PMLCOEMG_00526 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PMLCOEMG_00527 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PMLCOEMG_00528 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
PMLCOEMG_00529 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PMLCOEMG_00530 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PMLCOEMG_00531 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
PMLCOEMG_00532 3.5e-71 yqeY S YqeY-like protein
PMLCOEMG_00533 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PMLCOEMG_00534 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PMLCOEMG_00535 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
PMLCOEMG_00536 1e-95
PMLCOEMG_00537 1.1e-76 2.5.1.74 H UbiA prenyltransferase family
PMLCOEMG_00539 5.9e-185 3.2.1.18 GH33 M Rib/alpha-like repeat
PMLCOEMG_00540 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
PMLCOEMG_00541 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PMLCOEMG_00543 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PMLCOEMG_00544 2.4e-43 K Helix-turn-helix
PMLCOEMG_00545 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PMLCOEMG_00546 1.4e-226 pbuX F xanthine permease
PMLCOEMG_00547 2.5e-152 msmR K AraC-like ligand binding domain
PMLCOEMG_00548 4.4e-285 pipD E Dipeptidase
PMLCOEMG_00549 1.8e-74 K acetyltransferase
PMLCOEMG_00550 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PMLCOEMG_00551 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PMLCOEMG_00552 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PMLCOEMG_00553 6.9e-69 S Domain of unknown function (DUF1934)
PMLCOEMG_00554 3.2e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMLCOEMG_00555 5.6e-43
PMLCOEMG_00556 4.2e-172 2.7.1.2 GK ROK family
PMLCOEMG_00557 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMLCOEMG_00558 7.8e-292 S SLAP domain
PMLCOEMG_00559 5.3e-80
PMLCOEMG_00560 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PMLCOEMG_00561 8e-146 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PMLCOEMG_00562 4.5e-39 veg S Biofilm formation stimulator VEG
PMLCOEMG_00563 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PMLCOEMG_00564 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PMLCOEMG_00565 1e-147 tatD L hydrolase, TatD family
PMLCOEMG_00566 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PMLCOEMG_00567 2.5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PMLCOEMG_00568 2.4e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PMLCOEMG_00569 2e-103 S TPM domain
PMLCOEMG_00570 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
PMLCOEMG_00571 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMLCOEMG_00572 3.5e-111 E Belongs to the SOS response-associated peptidase family
PMLCOEMG_00574 1.2e-112
PMLCOEMG_00575 2.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PMLCOEMG_00576 1.5e-71 hsp O Belongs to the small heat shock protein (HSP20) family
PMLCOEMG_00577 1.8e-256 pepC 3.4.22.40 E aminopeptidase
PMLCOEMG_00578 4.2e-175 oppF P Belongs to the ABC transporter superfamily
PMLCOEMG_00579 2.7e-199 oppD P Belongs to the ABC transporter superfamily
PMLCOEMG_00580 6.8e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMLCOEMG_00581 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMLCOEMG_00582 1.7e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PMLCOEMG_00583 7.7e-310 oppA E ABC transporter, substratebinding protein
PMLCOEMG_00584 3.2e-300 oppA E ABC transporter, substratebinding protein
PMLCOEMG_00585 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMLCOEMG_00586 1.8e-256 pepC 3.4.22.40 E aminopeptidase
PMLCOEMG_00588 3.4e-53
PMLCOEMG_00589 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PMLCOEMG_00590 8.4e-265 S Fibronectin type III domain
PMLCOEMG_00591 4.8e-28
PMLCOEMG_00594 4.3e-67 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00595 3.3e-147 malG P ABC transporter permease
PMLCOEMG_00596 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
PMLCOEMG_00597 2.3e-213 malE G Bacterial extracellular solute-binding protein
PMLCOEMG_00598 3e-209 msmX P Belongs to the ABC transporter superfamily
PMLCOEMG_00599 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PMLCOEMG_00600 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PMLCOEMG_00601 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PMLCOEMG_00602 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
PMLCOEMG_00603 8.3e-24 papP P ABC transporter, permease protein
PMLCOEMG_00605 4.5e-58 yodB K Transcriptional regulator, HxlR family
PMLCOEMG_00606 2.2e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMLCOEMG_00607 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PMLCOEMG_00608 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PMLCOEMG_00609 5.7e-83 S Aminoacyl-tRNA editing domain
PMLCOEMG_00610 6.1e-224 S SLAP domain
PMLCOEMG_00611 1.5e-97 S CAAX protease self-immunity
PMLCOEMG_00612 1e-12
PMLCOEMG_00613 1.3e-277 arlS 2.7.13.3 T Histidine kinase
PMLCOEMG_00614 1.2e-126 K response regulator
PMLCOEMG_00615 4.7e-97 yceD S Uncharacterized ACR, COG1399
PMLCOEMG_00616 4.6e-216 ylbM S Belongs to the UPF0348 family
PMLCOEMG_00617 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PMLCOEMG_00618 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PMLCOEMG_00619 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PMLCOEMG_00620 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
PMLCOEMG_00621 4.2e-84 yqeG S HAD phosphatase, family IIIA
PMLCOEMG_00622 8.6e-199 tnpB L Putative transposase DNA-binding domain
PMLCOEMG_00623 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PMLCOEMG_00624 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PMLCOEMG_00625 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PMLCOEMG_00626 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PMLCOEMG_00627 2.7e-36 yyaR K Acetyltransferase (GNAT) domain
PMLCOEMG_00628 1.2e-108 yttB EGP Major facilitator Superfamily
PMLCOEMG_00629 0.0 pepO 3.4.24.71 O Peptidase family M13
PMLCOEMG_00630 0.0 kup P Transport of potassium into the cell
PMLCOEMG_00631 1.6e-73
PMLCOEMG_00633 1.6e-07 S PFAM Archaeal ATPase
PMLCOEMG_00635 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PMLCOEMG_00636 5.9e-45
PMLCOEMG_00637 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PMLCOEMG_00638 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PMLCOEMG_00639 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PMLCOEMG_00640 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PMLCOEMG_00641 9.6e-41 yajC U Preprotein translocase
PMLCOEMG_00642 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PMLCOEMG_00643 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PMLCOEMG_00644 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PMLCOEMG_00645 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PMLCOEMG_00646 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PMLCOEMG_00647 2e-42 yrzL S Belongs to the UPF0297 family
PMLCOEMG_00648 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PMLCOEMG_00649 1.1e-50 yrzB S Belongs to the UPF0473 family
PMLCOEMG_00650 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PMLCOEMG_00651 3.5e-54 trxA O Belongs to the thioredoxin family
PMLCOEMG_00652 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PMLCOEMG_00653 1.1e-71 yslB S Protein of unknown function (DUF2507)
PMLCOEMG_00654 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PMLCOEMG_00655 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PMLCOEMG_00656 7.7e-30 ropB K Helix-turn-helix domain
PMLCOEMG_00657 2.4e-282 phoR 2.7.13.3 T Histidine kinase
PMLCOEMG_00658 9.5e-121 T Transcriptional regulatory protein, C terminal
PMLCOEMG_00659 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
PMLCOEMG_00660 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PMLCOEMG_00661 1.2e-152 pstA P Phosphate transport system permease protein PstA
PMLCOEMG_00662 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
PMLCOEMG_00663 4.2e-145 pstS P Phosphate
PMLCOEMG_00664 1.3e-30
PMLCOEMG_00665 7e-191 oppA E ABC transporter, substratebinding protein
PMLCOEMG_00666 4.7e-275 ytgP S Polysaccharide biosynthesis protein
PMLCOEMG_00667 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMLCOEMG_00668 1.1e-121 3.6.1.27 I Acid phosphatase homologues
PMLCOEMG_00669 2.8e-168 K LysR substrate binding domain
PMLCOEMG_00670 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PMLCOEMG_00671 6.2e-43 1.3.5.4 C FAD binding domain
PMLCOEMG_00672 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
PMLCOEMG_00673 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PMLCOEMG_00674 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PMLCOEMG_00675 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PMLCOEMG_00676 2.5e-121 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PMLCOEMG_00677 9.5e-152 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PMLCOEMG_00678 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PMLCOEMG_00679 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PMLCOEMG_00680 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
PMLCOEMG_00681 3.7e-130 ybbH_2 K rpiR family
PMLCOEMG_00682 3.4e-195 S Bacterial protein of unknown function (DUF871)
PMLCOEMG_00683 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
PMLCOEMG_00684 1.8e-119 S Putative esterase
PMLCOEMG_00685 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PMLCOEMG_00686 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
PMLCOEMG_00688 8.5e-260 qacA EGP Major facilitator Superfamily
PMLCOEMG_00689 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PMLCOEMG_00692 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
PMLCOEMG_00693 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
PMLCOEMG_00694 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
PMLCOEMG_00695 2.6e-280 thrC 4.2.3.1 E Threonine synthase
PMLCOEMG_00696 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PMLCOEMG_00697 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PMLCOEMG_00698 9.4e-118
PMLCOEMG_00699 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PMLCOEMG_00701 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMLCOEMG_00702 1.3e-116 S Peptidase family M23
PMLCOEMG_00703 1.1e-56 S Protein of unknown function (DUF3290)
PMLCOEMG_00704 3e-116 yviA S Protein of unknown function (DUF421)
PMLCOEMG_00705 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PMLCOEMG_00706 8e-182 dnaQ 2.7.7.7 L EXOIII
PMLCOEMG_00707 1.9e-158 endA F DNA RNA non-specific endonuclease
PMLCOEMG_00708 1.3e-281 pipD E Dipeptidase
PMLCOEMG_00709 1.9e-203 malK P ATPases associated with a variety of cellular activities
PMLCOEMG_00710 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
PMLCOEMG_00711 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
PMLCOEMG_00712 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
PMLCOEMG_00713 2.3e-240 G Bacterial extracellular solute-binding protein
PMLCOEMG_00714 1.8e-154 corA P CorA-like Mg2+ transporter protein
PMLCOEMG_00715 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
PMLCOEMG_00716 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
PMLCOEMG_00717 0.0 ydgH S MMPL family
PMLCOEMG_00719 7.8e-26 K Acetyltransferase (GNAT) domain
PMLCOEMG_00720 1.8e-163
PMLCOEMG_00721 7.5e-231 pbuG S permease
PMLCOEMG_00722 2.5e-119 K helix_turn_helix, mercury resistance
PMLCOEMG_00723 3.3e-37
PMLCOEMG_00724 2e-234 mepA V MATE efflux family protein
PMLCOEMG_00725 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
PMLCOEMG_00726 1.8e-58 S Putative adhesin
PMLCOEMG_00727 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMLCOEMG_00728 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
PMLCOEMG_00729 1.1e-83 dps P Belongs to the Dps family
PMLCOEMG_00730 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
PMLCOEMG_00731 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
PMLCOEMG_00732 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
PMLCOEMG_00733 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PMLCOEMG_00734 3.8e-115 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PMLCOEMG_00735 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PMLCOEMG_00736 6.7e-245 ynbB 4.4.1.1 P aluminum resistance
PMLCOEMG_00737 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
PMLCOEMG_00738 5.5e-283 E Amino acid permease
PMLCOEMG_00739 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
PMLCOEMG_00740 6.5e-273 pepV 3.5.1.18 E dipeptidase PepV
PMLCOEMG_00741 1.2e-116 mmuP E amino acid
PMLCOEMG_00742 3.2e-12 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PMLCOEMG_00743 2.7e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMLCOEMG_00744 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMLCOEMG_00745 6.2e-151 xerD L Phage integrase, N-terminal SAM-like domain
PMLCOEMG_00746 7.1e-63 M LysM domain protein
PMLCOEMG_00747 5.7e-27 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PMLCOEMG_00748 2.6e-166 xerD D recombinase XerD
PMLCOEMG_00749 1.9e-169 cvfB S S1 domain
PMLCOEMG_00750 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PMLCOEMG_00751 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PMLCOEMG_00752 0.0 dnaE 2.7.7.7 L DNA polymerase
PMLCOEMG_00753 2.3e-23 S Protein of unknown function (DUF2929)
PMLCOEMG_00754 4.3e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PMLCOEMG_00755 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PMLCOEMG_00756 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
PMLCOEMG_00757 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PMLCOEMG_00758 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PMLCOEMG_00759 2.2e-292 I Acyltransferase
PMLCOEMG_00760 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PMLCOEMG_00761 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PMLCOEMG_00762 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
PMLCOEMG_00763 4e-243 yfnA E Amino Acid
PMLCOEMG_00764 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMLCOEMG_00765 1.3e-148 yxeH S hydrolase
PMLCOEMG_00766 2.7e-32 S reductase
PMLCOEMG_00767 4.4e-39 S reductase
PMLCOEMG_00768 4.8e-34 S reductase
PMLCOEMG_00769 2e-68 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PMLCOEMG_00770 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PMLCOEMG_00771 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PMLCOEMG_00772 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PMLCOEMG_00773 7.5e-178 MA20_14895 S Conserved hypothetical protein 698
PMLCOEMG_00775 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PMLCOEMG_00776 6.4e-71 scrR K Periplasmic binding protein domain
PMLCOEMG_00777 5.5e-36
PMLCOEMG_00778 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PMLCOEMG_00779 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PMLCOEMG_00780 3.8e-193 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PMLCOEMG_00781 0.0 lacZ 3.2.1.23 G -beta-galactosidase
PMLCOEMG_00782 2.6e-103 lacS G Transporter
PMLCOEMG_00783 8.9e-207 lacS G Transporter
PMLCOEMG_00784 7.1e-165 lacR K Transcriptional regulator
PMLCOEMG_00785 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PMLCOEMG_00786 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PMLCOEMG_00787 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PMLCOEMG_00788 2e-188 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PMLCOEMG_00789 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
PMLCOEMG_00790 2e-106 K Transcriptional regulator, AbiEi antitoxin
PMLCOEMG_00791 1.2e-188 K Periplasmic binding protein-like domain
PMLCOEMG_00792 1.4e-175 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PMLCOEMG_00793 1.4e-16 L Transposase
PMLCOEMG_00794 1.9e-12 L Transposase
PMLCOEMG_00795 5.9e-13 K Acetyltransferase (GNAT) domain
PMLCOEMG_00796 2.2e-120 lsa S ABC transporter
PMLCOEMG_00797 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMLCOEMG_00798 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PMLCOEMG_00799 3.3e-237 L COG2963 Transposase and inactivated derivatives
PMLCOEMG_00800 4.7e-46 pspC KT PspC domain
PMLCOEMG_00802 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PMLCOEMG_00803 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PMLCOEMG_00804 6.7e-98 M ErfK YbiS YcfS YnhG
PMLCOEMG_00805 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PMLCOEMG_00806 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PMLCOEMG_00807 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PMLCOEMG_00808 2.1e-168 dnaI L Primosomal protein DnaI
PMLCOEMG_00809 5.1e-251 dnaB L Replication initiation and membrane attachment
PMLCOEMG_00810 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PMLCOEMG_00811 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PMLCOEMG_00812 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PMLCOEMG_00813 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PMLCOEMG_00814 3.5e-25 qmcA O prohibitin homologues
PMLCOEMG_00815 7.4e-105 qmcA O prohibitin homologues
PMLCOEMG_00816 8e-51 L RelB antitoxin
PMLCOEMG_00817 4.5e-188 S Bacteriocin helveticin-J
PMLCOEMG_00818 4.4e-283 M Peptidase family M1 domain
PMLCOEMG_00819 1.8e-176 S SLAP domain
PMLCOEMG_00820 6.9e-218 mepA V MATE efflux family protein
PMLCOEMG_00821 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PMLCOEMG_00822 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PMLCOEMG_00823 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PMLCOEMG_00825 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PMLCOEMG_00826 6.5e-221 ecsB U ABC transporter
PMLCOEMG_00827 5.7e-135 ecsA V ABC transporter, ATP-binding protein
PMLCOEMG_00828 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
PMLCOEMG_00829 9.7e-24
PMLCOEMG_00830 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PMLCOEMG_00831 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
PMLCOEMG_00832 1.1e-265
PMLCOEMG_00833 2.4e-51 S Domain of unknown function DUF1829
PMLCOEMG_00834 1.5e-145 yfeO P Voltage gated chloride channel
PMLCOEMG_00835 4e-184 5.3.3.2 C FMN-dependent dehydrogenase
PMLCOEMG_00836 2.8e-52
PMLCOEMG_00837 2.7e-138
PMLCOEMG_00838 2.8e-202 steT E amino acid
PMLCOEMG_00839 2e-25 steT E amino acid
PMLCOEMG_00840 8.6e-243 steT E amino acid
PMLCOEMG_00841 7.4e-40 yabO J S4 domain protein
PMLCOEMG_00842 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PMLCOEMG_00843 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PMLCOEMG_00844 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PMLCOEMG_00845 3.4e-129 S (CBS) domain
PMLCOEMG_00846 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PMLCOEMG_00847 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PMLCOEMG_00848 1.9e-251 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PMLCOEMG_00849 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PMLCOEMG_00850 2.5e-39 rpmE2 J Ribosomal protein L31
PMLCOEMG_00851 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
PMLCOEMG_00852 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
PMLCOEMG_00853 3.3e-297 ybeC E amino acid
PMLCOEMG_00854 2.4e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PMLCOEMG_00855 4e-22
PMLCOEMG_00856 2.9e-12
PMLCOEMG_00857 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PMLCOEMG_00858 2.6e-86 M Protein of unknown function (DUF3737)
PMLCOEMG_00859 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
PMLCOEMG_00860 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
PMLCOEMG_00861 7.7e-67 S SdpI/YhfL protein family
PMLCOEMG_00862 4.4e-129 K Transcriptional regulatory protein, C terminal
PMLCOEMG_00863 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
PMLCOEMG_00864 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PMLCOEMG_00865 3.8e-105 vanZ V VanZ like family
PMLCOEMG_00866 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
PMLCOEMG_00867 3.8e-217 EGP Major facilitator Superfamily
PMLCOEMG_00868 3.9e-195 ampC V Beta-lactamase
PMLCOEMG_00871 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PMLCOEMG_00872 1.3e-113 tdk 2.7.1.21 F thymidine kinase
PMLCOEMG_00873 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PMLCOEMG_00874 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PMLCOEMG_00875 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PMLCOEMG_00876 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PMLCOEMG_00877 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
PMLCOEMG_00878 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMLCOEMG_00879 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PMLCOEMG_00880 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMLCOEMG_00881 1.8e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PMLCOEMG_00882 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PMLCOEMG_00883 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PMLCOEMG_00884 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PMLCOEMG_00885 2e-30 ywzB S Protein of unknown function (DUF1146)
PMLCOEMG_00886 1.2e-177 mbl D Cell shape determining protein MreB Mrl
PMLCOEMG_00887 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PMLCOEMG_00888 3.3e-33 S Protein of unknown function (DUF2969)
PMLCOEMG_00889 4.7e-216 rodA D Belongs to the SEDS family
PMLCOEMG_00890 1.8e-78 usp6 T universal stress protein
PMLCOEMG_00891 8.4e-39
PMLCOEMG_00892 2.2e-238 rarA L recombination factor protein RarA
PMLCOEMG_00893 1.3e-84 yueI S Protein of unknown function (DUF1694)
PMLCOEMG_00894 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PMLCOEMG_00895 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PMLCOEMG_00896 4.8e-213 iscS2 2.8.1.7 E Aminotransferase class V
PMLCOEMG_00897 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PMLCOEMG_00898 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PMLCOEMG_00899 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PMLCOEMG_00900 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PMLCOEMG_00901 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
PMLCOEMG_00902 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PMLCOEMG_00903 1.5e-94 S Protein of unknown function (DUF3990)
PMLCOEMG_00904 6.5e-44
PMLCOEMG_00906 0.0 3.6.3.8 P P-type ATPase
PMLCOEMG_00907 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
PMLCOEMG_00908 2.5e-52
PMLCOEMG_00909 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PMLCOEMG_00910 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PMLCOEMG_00911 5.7e-126 S Haloacid dehalogenase-like hydrolase
PMLCOEMG_00912 2.3e-108 radC L DNA repair protein
PMLCOEMG_00913 2.4e-176 mreB D cell shape determining protein MreB
PMLCOEMG_00914 2e-147 mreC M Involved in formation and maintenance of cell shape
PMLCOEMG_00915 2.7e-94 mreD
PMLCOEMG_00917 6.4e-54 S Protein of unknown function (DUF3397)
PMLCOEMG_00918 6.3e-78 mraZ K Belongs to the MraZ family
PMLCOEMG_00919 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PMLCOEMG_00920 1.8e-54 ftsL D Cell division protein FtsL
PMLCOEMG_00921 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PMLCOEMG_00922 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PMLCOEMG_00923 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PMLCOEMG_00924 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PMLCOEMG_00925 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PMLCOEMG_00926 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PMLCOEMG_00927 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PMLCOEMG_00928 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PMLCOEMG_00929 1.7e-45 yggT S YGGT family
PMLCOEMG_00930 5.7e-149 ylmH S S4 domain protein
PMLCOEMG_00931 2.8e-74 gpsB D DivIVA domain protein
PMLCOEMG_00932 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PMLCOEMG_00933 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
PMLCOEMG_00934 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PMLCOEMG_00935 6.7e-37
PMLCOEMG_00936 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PMLCOEMG_00937 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
PMLCOEMG_00938 5.4e-56 XK27_04120 S Putative amino acid metabolism
PMLCOEMG_00939 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PMLCOEMG_00940 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PMLCOEMG_00941 8.3e-106 S Repeat protein
PMLCOEMG_00942 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PMLCOEMG_00943 1.6e-294 L Nuclease-related domain
PMLCOEMG_00944 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PMLCOEMG_00945 9.2e-262 emrY EGP Major facilitator Superfamily
PMLCOEMG_00946 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PMLCOEMG_00947 7.6e-239 pyrP F Permease
PMLCOEMG_00948 1.9e-22 K Putative DNA-binding domain
PMLCOEMG_00949 2.3e-121 V Abi-like protein
PMLCOEMG_00950 4e-137 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_00951 2.3e-18
PMLCOEMG_00952 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PMLCOEMG_00953 3.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PMLCOEMG_00954 7e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
PMLCOEMG_00955 3.1e-178 yvdE K helix_turn _helix lactose operon repressor
PMLCOEMG_00956 9.1e-204 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMLCOEMG_00957 4.6e-58 S PAS domain
PMLCOEMG_00958 0.0 L Plasmid pRiA4b ORF-3-like protein
PMLCOEMG_00959 3.1e-136 glcR K DeoR C terminal sensor domain
PMLCOEMG_00960 2.5e-59 S Enterocin A Immunity
PMLCOEMG_00961 1.2e-154 S hydrolase
PMLCOEMG_00962 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
PMLCOEMG_00963 9.1e-175 rihB 3.2.2.1 F Nucleoside
PMLCOEMG_00964 0.0 kup P Transport of potassium into the cell
PMLCOEMG_00965 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PMLCOEMG_00966 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMLCOEMG_00967 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
PMLCOEMG_00970 4.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
PMLCOEMG_00973 1.2e-32 M Peptidase family M23
PMLCOEMG_00974 1.8e-159 trsE S COG0433 Predicted ATPase
PMLCOEMG_00975 4.9e-15
PMLCOEMG_00977 1e-32 I mechanosensitive ion channel activity
PMLCOEMG_00978 2e-140 U TraM recognition site of TraD and TraG
PMLCOEMG_00982 5e-38 M domain protein
PMLCOEMG_00983 4.6e-42 M domain protein
PMLCOEMG_00985 1.4e-24 srtA 3.4.22.70 M sortase family
PMLCOEMG_00986 1.6e-21 S SLAP domain
PMLCOEMG_00991 2.6e-11 ssb L Single-strand binding protein family
PMLCOEMG_00999 3.2e-24 S Domain of unknown function (DUF771)
PMLCOEMG_01000 8.9e-32 K Helix-turn-helix domain
PMLCOEMG_01001 1.2e-21 XK27_07105 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_01002 1.2e-23 K Helix-turn-helix domain
PMLCOEMG_01003 5e-08 S Pfam:DUF955
PMLCOEMG_01004 1.4e-153 L Belongs to the 'phage' integrase family
PMLCOEMG_01006 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMLCOEMG_01007 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
PMLCOEMG_01008 1.6e-21
PMLCOEMG_01009 3.8e-77 comGF U Putative Competence protein ComGF
PMLCOEMG_01010 2.3e-41
PMLCOEMG_01011 1.8e-69
PMLCOEMG_01012 3.1e-43 comGC U competence protein ComGC
PMLCOEMG_01013 1.7e-171 comGB NU type II secretion system
PMLCOEMG_01014 1.7e-179 comGA NU Type II IV secretion system protein
PMLCOEMG_01015 8.9e-133 yebC K Transcriptional regulatory protein
PMLCOEMG_01016 7.6e-94 S VanZ like family
PMLCOEMG_01017 4.3e-25 ylbE GM NAD(P)H-binding
PMLCOEMG_01018 9.3e-86
PMLCOEMG_01019 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMLCOEMG_01020 1.6e-182 S Alpha/beta hydrolase of unknown function (DUF915)
PMLCOEMG_01021 8.8e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMLCOEMG_01022 4.4e-140 ypuA S Protein of unknown function (DUF1002)
PMLCOEMG_01023 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
PMLCOEMG_01024 7.3e-126 S Alpha/beta hydrolase family
PMLCOEMG_01025 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
PMLCOEMG_01026 2e-157 S reductase
PMLCOEMG_01027 9.3e-35
PMLCOEMG_01028 5.5e-36 S Alpha beta hydrolase
PMLCOEMG_01029 6e-66 S Alpha beta hydrolase
PMLCOEMG_01030 1.9e-37
PMLCOEMG_01031 4.9e-38
PMLCOEMG_01032 2.4e-147 S haloacid dehalogenase-like hydrolase
PMLCOEMG_01033 2.5e-289 V ABC-type multidrug transport system, ATPase and permease components
PMLCOEMG_01034 2e-275 V ABC-type multidrug transport system, ATPase and permease components
PMLCOEMG_01035 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
PMLCOEMG_01036 6.1e-145 I Carboxylesterase family
PMLCOEMG_01038 1.7e-205 M Glycosyl hydrolases family 25
PMLCOEMG_01039 1.3e-157 cinI S Serine hydrolase (FSH1)
PMLCOEMG_01040 2.7e-300 S Predicted membrane protein (DUF2207)
PMLCOEMG_01041 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PMLCOEMG_01044 3.3e-303 L Transposase
PMLCOEMG_01045 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
PMLCOEMG_01046 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PMLCOEMG_01047 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PMLCOEMG_01048 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PMLCOEMG_01049 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PMLCOEMG_01050 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PMLCOEMG_01051 9.8e-71 yqhY S Asp23 family, cell envelope-related function
PMLCOEMG_01052 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PMLCOEMG_01053 2.2e-143 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PMLCOEMG_01054 7.6e-186 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PMLCOEMG_01055 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PMLCOEMG_01056 2.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PMLCOEMG_01057 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PMLCOEMG_01058 8.8e-293 recN L May be involved in recombinational repair of damaged DNA
PMLCOEMG_01059 1.1e-77 6.3.3.2 S ASCH
PMLCOEMG_01060 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
PMLCOEMG_01061 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PMLCOEMG_01062 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PMLCOEMG_01063 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PMLCOEMG_01064 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PMLCOEMG_01065 1.3e-139 stp 3.1.3.16 T phosphatase
PMLCOEMG_01066 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PMLCOEMG_01067 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PMLCOEMG_01068 3.8e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PMLCOEMG_01069 2.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
PMLCOEMG_01070 1.1e-30
PMLCOEMG_01071 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PMLCOEMG_01072 4e-57 asp S Asp23 family, cell envelope-related function
PMLCOEMG_01073 3.4e-305 yloV S DAK2 domain fusion protein YloV
PMLCOEMG_01074 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PMLCOEMG_01075 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PMLCOEMG_01076 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMLCOEMG_01077 1.1e-192 oppD P Belongs to the ABC transporter superfamily
PMLCOEMG_01078 1.5e-170 oppF P Belongs to the ABC transporter superfamily
PMLCOEMG_01079 2.6e-172 oppB P ABC transporter permease
PMLCOEMG_01080 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
PMLCOEMG_01081 9.7e-46 oppA E ABC transporter substrate-binding protein
PMLCOEMG_01082 7.5e-103 G Phosphoglycerate mutase family
PMLCOEMG_01083 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PMLCOEMG_01085 3.5e-80 S AAA domain
PMLCOEMG_01086 1.2e-40 3.6.1.55 F NUDIX domain
PMLCOEMG_01087 6.2e-145 2.4.2.3 F Phosphorylase superfamily
PMLCOEMG_01088 2.2e-149 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
PMLCOEMG_01089 7.6e-100 yagE E Amino acid permease
PMLCOEMG_01090 5.6e-34 yagE E Amino acid permease
PMLCOEMG_01091 7.3e-86 3.4.21.96 S SLAP domain
PMLCOEMG_01092 7.9e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PMLCOEMG_01093 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PMLCOEMG_01094 1.2e-107 hlyIII S protein, hemolysin III
PMLCOEMG_01095 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
PMLCOEMG_01096 7.1e-36 yozE S Belongs to the UPF0346 family
PMLCOEMG_01097 1.1e-66 yjcE P NhaP-type Na H and K H
PMLCOEMG_01098 1.5e-40 yjcE P Sodium proton antiporter
PMLCOEMG_01099 1.9e-94 yjcE P Sodium proton antiporter
PMLCOEMG_01100 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PMLCOEMG_01101 1.5e-130 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMLCOEMG_01102 5.8e-152 dprA LU DNA protecting protein DprA
PMLCOEMG_01103 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PMLCOEMG_01104 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PMLCOEMG_01105 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
PMLCOEMG_01106 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PMLCOEMG_01107 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PMLCOEMG_01108 1.4e-83 K FR47-like protein
PMLCOEMG_01109 1.6e-08
PMLCOEMG_01111 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
PMLCOEMG_01112 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PMLCOEMG_01113 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMLCOEMG_01114 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMLCOEMG_01115 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PMLCOEMG_01116 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PMLCOEMG_01117 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PMLCOEMG_01118 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PMLCOEMG_01119 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PMLCOEMG_01120 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PMLCOEMG_01121 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
PMLCOEMG_01122 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PMLCOEMG_01123 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PMLCOEMG_01124 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PMLCOEMG_01125 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PMLCOEMG_01126 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PMLCOEMG_01127 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PMLCOEMG_01128 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
PMLCOEMG_01129 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PMLCOEMG_01130 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PMLCOEMG_01131 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PMLCOEMG_01132 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PMLCOEMG_01133 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PMLCOEMG_01134 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PMLCOEMG_01135 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PMLCOEMG_01136 1.1e-54 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PMLCOEMG_01137 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PMLCOEMG_01138 2.3e-24 rpmD J Ribosomal protein L30
PMLCOEMG_01139 2.6e-71 rplO J Binds to the 23S rRNA
PMLCOEMG_01140 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PMLCOEMG_01141 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PMLCOEMG_01142 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PMLCOEMG_01143 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PMLCOEMG_01144 3.6e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PMLCOEMG_01145 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PMLCOEMG_01146 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMLCOEMG_01147 1.4e-60 rplQ J Ribosomal protein L17
PMLCOEMG_01148 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMLCOEMG_01149 4.6e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMLCOEMG_01150 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMLCOEMG_01151 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PMLCOEMG_01152 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PMLCOEMG_01153 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
PMLCOEMG_01154 8.9e-133 L Phage integrase family
PMLCOEMG_01155 0.0 pacL 3.6.3.8 P P-type ATPase
PMLCOEMG_01156 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PMLCOEMG_01157 3e-257 epsU S Polysaccharide biosynthesis protein
PMLCOEMG_01158 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
PMLCOEMG_01159 4.1e-83 ydcK S Belongs to the SprT family
PMLCOEMG_01161 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
PMLCOEMG_01162 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PMLCOEMG_01163 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMLCOEMG_01164 5.8e-203 camS S sex pheromone
PMLCOEMG_01165 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMLCOEMG_01166 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PMLCOEMG_01167 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMLCOEMG_01168 2.7e-171 yegS 2.7.1.107 G Lipid kinase
PMLCOEMG_01169 4.3e-108 ybhL S Belongs to the BI1 family
PMLCOEMG_01170 2.6e-57
PMLCOEMG_01171 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
PMLCOEMG_01172 2.8e-244 nhaC C Na H antiporter NhaC
PMLCOEMG_01173 6.3e-201 pbpX V Beta-lactamase
PMLCOEMG_01174 1.4e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMLCOEMG_01175 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
PMLCOEMG_01176 2.1e-308 oppA E ABC transporter substrate-binding protein
PMLCOEMG_01177 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PMLCOEMG_01178 0.0 smc D Required for chromosome condensation and partitioning
PMLCOEMG_01179 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PMLCOEMG_01180 2.5e-288 pipD E Dipeptidase
PMLCOEMG_01182 3.4e-23
PMLCOEMG_01183 4.1e-133 cysA V ABC transporter, ATP-binding protein
PMLCOEMG_01184 0.0 V FtsX-like permease family
PMLCOEMG_01185 2.7e-258 yfnA E amino acid
PMLCOEMG_01186 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PMLCOEMG_01187 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PMLCOEMG_01188 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PMLCOEMG_01189 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PMLCOEMG_01190 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PMLCOEMG_01191 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PMLCOEMG_01192 4.6e-213 S SLAP domain
PMLCOEMG_01193 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
PMLCOEMG_01194 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
PMLCOEMG_01195 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PMLCOEMG_01196 3e-38 ynzC S UPF0291 protein
PMLCOEMG_01197 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
PMLCOEMG_01198 0.0 mdlA V ABC transporter
PMLCOEMG_01199 0.0 mdlB V ABC transporter
PMLCOEMG_01200 0.0 pepO 3.4.24.71 O Peptidase family M13
PMLCOEMG_01201 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PMLCOEMG_01202 2.9e-116 plsC 2.3.1.51 I Acyltransferase
PMLCOEMG_01203 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
PMLCOEMG_01204 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
PMLCOEMG_01205 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PMLCOEMG_01206 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PMLCOEMG_01207 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PMLCOEMG_01208 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PMLCOEMG_01209 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
PMLCOEMG_01210 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PMLCOEMG_01211 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PMLCOEMG_01212 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMLCOEMG_01213 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
PMLCOEMG_01214 1.2e-195 nusA K Participates in both transcription termination and antitermination
PMLCOEMG_01215 8.8e-47 ylxR K Protein of unknown function (DUF448)
PMLCOEMG_01216 3.2e-47 rplGA J ribosomal protein
PMLCOEMG_01217 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PMLCOEMG_01218 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PMLCOEMG_01219 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PMLCOEMG_01220 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PMLCOEMG_01221 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PMLCOEMG_01222 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PMLCOEMG_01223 0.0 dnaK O Heat shock 70 kDa protein
PMLCOEMG_01224 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PMLCOEMG_01225 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PMLCOEMG_01226 1.5e-102 srtA 3.4.22.70 M sortase family
PMLCOEMG_01227 1.4e-301 recJ L Single-stranded-DNA-specific exonuclease RecJ
PMLCOEMG_01228 1.5e-36 oppA E ABC transporter substrate-binding protein
PMLCOEMG_01230 1.4e-31 O OsmC-like protein
PMLCOEMG_01231 5.4e-113
PMLCOEMG_01232 1.7e-139
PMLCOEMG_01233 6.9e-100 V ATPases associated with a variety of cellular activities
PMLCOEMG_01234 3.7e-146 ykuT M mechanosensitive ion channel
PMLCOEMG_01235 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PMLCOEMG_01236 1.3e-36
PMLCOEMG_01237 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PMLCOEMG_01238 3.2e-181 ccpA K catabolite control protein A
PMLCOEMG_01239 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PMLCOEMG_01240 4.3e-55
PMLCOEMG_01241 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PMLCOEMG_01242 2.1e-92 yutD S Protein of unknown function (DUF1027)
PMLCOEMG_01243 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PMLCOEMG_01244 3.7e-100 S Protein of unknown function (DUF1461)
PMLCOEMG_01245 6.8e-116 dedA S SNARE-like domain protein
PMLCOEMG_01246 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
PMLCOEMG_01247 4.4e-222 patA 2.6.1.1 E Aminotransferase
PMLCOEMG_01248 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PMLCOEMG_01249 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
PMLCOEMG_01250 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PMLCOEMG_01251 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMLCOEMG_01252 8.5e-60
PMLCOEMG_01253 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
PMLCOEMG_01254 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PMLCOEMG_01255 5.9e-37 M domain protein
PMLCOEMG_01257 6.2e-249 yjjP S Putative threonine/serine exporter
PMLCOEMG_01258 9.1e-66 L An automated process has identified a potential problem with this gene model
PMLCOEMG_01259 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PMLCOEMG_01260 5e-148 noc K Belongs to the ParB family
PMLCOEMG_01261 3.4e-138 soj D Sporulation initiation inhibitor
PMLCOEMG_01262 1.5e-153 spo0J K Belongs to the ParB family
PMLCOEMG_01263 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
PMLCOEMG_01264 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PMLCOEMG_01265 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
PMLCOEMG_01266 1.2e-145 V ABC transporter, ATP-binding protein
PMLCOEMG_01267 4.2e-144 V ABC transporter, ATP-binding protein
PMLCOEMG_01268 0.0 V ABC transporter
PMLCOEMG_01270 9.6e-121 K response regulator
PMLCOEMG_01271 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
PMLCOEMG_01272 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PMLCOEMG_01273 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PMLCOEMG_01274 1.4e-53 S Enterocin A Immunity
PMLCOEMG_01275 2.5e-33
PMLCOEMG_01276 9.5e-26
PMLCOEMG_01277 1e-24
PMLCOEMG_01278 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
PMLCOEMG_01279 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
PMLCOEMG_01280 2.1e-255 S Archaea bacterial proteins of unknown function
PMLCOEMG_01281 1.2e-16
PMLCOEMG_01282 4.4e-138 2.7.13.3 T GHKL domain
PMLCOEMG_01283 1.2e-127 K LytTr DNA-binding domain
PMLCOEMG_01284 6.1e-269 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PMLCOEMG_01285 5.9e-174 S Aldo keto reductase
PMLCOEMG_01286 2.2e-311 ybiT S ABC transporter, ATP-binding protein
PMLCOEMG_01287 4.7e-182 pepA E M42 glutamyl aminopeptidase
PMLCOEMG_01288 1.4e-110 yjbF S SNARE associated Golgi protein
PMLCOEMG_01289 7.5e-100 J Acetyltransferase (GNAT) domain
PMLCOEMG_01290 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PMLCOEMG_01291 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
PMLCOEMG_01292 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
PMLCOEMG_01293 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
PMLCOEMG_01294 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
PMLCOEMG_01295 3.8e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
PMLCOEMG_01296 4.4e-151 S Metal-independent alpha-mannosidase (GH125)
PMLCOEMG_01297 8.1e-126 S PAS domain
PMLCOEMG_01298 1.6e-11
PMLCOEMG_01299 2.7e-57
PMLCOEMG_01300 6.6e-56
PMLCOEMG_01301 4e-08
PMLCOEMG_01302 1.9e-19
PMLCOEMG_01303 2.5e-264 3.6.3.6 P Cation transporter/ATPase, N-terminus
PMLCOEMG_01304 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
PMLCOEMG_01305 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
PMLCOEMG_01306 0.0 L PLD-like domain
PMLCOEMG_01307 4.8e-42 S SnoaL-like domain
PMLCOEMG_01308 5.4e-53 hipB K sequence-specific DNA binding
PMLCOEMG_01309 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
PMLCOEMG_01310 3.4e-27
PMLCOEMG_01311 1e-20 S Enterocin A Immunity
PMLCOEMG_01313 5.7e-43 2.4.1.33 V HlyD family secretion protein
PMLCOEMG_01314 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PMLCOEMG_01315 2.9e-79 K LytTr DNA-binding domain
PMLCOEMG_01316 2.1e-78 2.7.13.3 T GHKL domain
PMLCOEMG_01317 1e-48 S Metal binding domain of Ada
PMLCOEMG_01318 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
PMLCOEMG_01319 9e-137 lysR5 K LysR substrate binding domain
PMLCOEMG_01320 8.8e-234 arcA 3.5.3.6 E Arginine
PMLCOEMG_01321 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PMLCOEMG_01322 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
PMLCOEMG_01323 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PMLCOEMG_01324 2.3e-215 S Sterol carrier protein domain
PMLCOEMG_01325 1e-20
PMLCOEMG_01326 4.9e-108 K LysR substrate binding domain
PMLCOEMG_01327 9e-98
PMLCOEMG_01328 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
PMLCOEMG_01329 2.7e-83 S Protein of unknown function (DUF1211)
PMLCOEMG_01330 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
PMLCOEMG_01331 2.8e-119 3.6.1.55 F NUDIX domain
PMLCOEMG_01332 3e-246 brnQ U Component of the transport system for branched-chain amino acids
PMLCOEMG_01334 1.1e-81 M NlpC/P60 family
PMLCOEMG_01335 2.1e-131 cobQ S glutamine amidotransferase
PMLCOEMG_01336 6.5e-64 L RelB antitoxin
PMLCOEMG_01337 1.2e-201 V ABC transporter transmembrane region
PMLCOEMG_01338 6.8e-186 G Transmembrane secretion effector
PMLCOEMG_01339 5.8e-78 M LysM domain protein
PMLCOEMG_01340 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLCOEMG_01341 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLCOEMG_01342 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLCOEMG_01343 6.2e-12
PMLCOEMG_01344 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
PMLCOEMG_01345 2.3e-30
PMLCOEMG_01347 2.9e-69 S Iron-sulphur cluster biosynthesis
PMLCOEMG_01348 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
PMLCOEMG_01349 6.2e-59 psiE S Phosphate-starvation-inducible E
PMLCOEMG_01351 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PMLCOEMG_01352 4.3e-228 amtB P ammonium transporter
PMLCOEMG_01353 1.4e-60
PMLCOEMG_01354 0.0 lhr L DEAD DEAH box helicase
PMLCOEMG_01355 5.4e-245 P P-loop Domain of unknown function (DUF2791)
PMLCOEMG_01356 2.6e-138 S TerB-C domain
PMLCOEMG_01357 9.8e-94 yttB EGP Major facilitator Superfamily
PMLCOEMG_01358 1.5e-230 XK27_04775 S PAS domain
PMLCOEMG_01359 2.1e-103 S Iron-sulfur cluster assembly protein
PMLCOEMG_01360 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PMLCOEMG_01361 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PMLCOEMG_01362 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
PMLCOEMG_01363 0.0 asnB 6.3.5.4 E Asparagine synthase
PMLCOEMG_01364 3.5e-271 S Calcineurin-like phosphoesterase
PMLCOEMG_01365 3.9e-84
PMLCOEMG_01366 1.6e-105 tag 3.2.2.20 L glycosylase
PMLCOEMG_01367 4.5e-168 L COG3385 FOG Transposase and inactivated derivatives
PMLCOEMG_01368 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PMLCOEMG_01369 3.5e-32 ykzG S Belongs to the UPF0356 family
PMLCOEMG_01370 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PMLCOEMG_01371 0.0 typA T GTP-binding protein TypA
PMLCOEMG_01372 5.9e-211 ftsW D Belongs to the SEDS family
PMLCOEMG_01373 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PMLCOEMG_01374 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PMLCOEMG_01375 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PMLCOEMG_01376 2.4e-187 ylbL T Belongs to the peptidase S16 family
PMLCOEMG_01377 3.1e-79 comEA L Competence protein ComEA
PMLCOEMG_01378 0.0 comEC S Competence protein ComEC
PMLCOEMG_01379 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
PMLCOEMG_01380 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
PMLCOEMG_01381 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PMLCOEMG_01382 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PMLCOEMG_01383 1.3e-148
PMLCOEMG_01384 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PMLCOEMG_01385 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PMLCOEMG_01386 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PMLCOEMG_01387 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
PMLCOEMG_01388 7.8e-39 yjeM E Amino Acid
PMLCOEMG_01389 3.4e-175 yjeM E Amino Acid
PMLCOEMG_01390 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PMLCOEMG_01391 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
PMLCOEMG_01392 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PMLCOEMG_01393 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PMLCOEMG_01394 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PMLCOEMG_01395 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMLCOEMG_01396 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PMLCOEMG_01397 3.2e-217 aspC 2.6.1.1 E Aminotransferase
PMLCOEMG_01398 1.1e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PMLCOEMG_01399 1.2e-141 pbpX1 V Beta-lactamase
PMLCOEMG_01400 7.9e-299 I Protein of unknown function (DUF2974)
PMLCOEMG_01401 6.8e-31 C FMN_bind
PMLCOEMG_01402 3.9e-82
PMLCOEMG_01403 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
PMLCOEMG_01404 6.4e-90 alkD L DNA alkylation repair enzyme
PMLCOEMG_01405 1.2e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLCOEMG_01406 6.4e-128 K UTRA domain
PMLCOEMG_01407 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLCOEMG_01408 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
PMLCOEMG_01409 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PMLCOEMG_01410 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PMLCOEMG_01411 2.6e-214 yubA S AI-2E family transporter
PMLCOEMG_01412 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PMLCOEMG_01413 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
PMLCOEMG_01414 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PMLCOEMG_01415 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
PMLCOEMG_01416 1.9e-236 S Peptidase M16
PMLCOEMG_01417 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
PMLCOEMG_01418 5.2e-97 ymfM S Helix-turn-helix domain
PMLCOEMG_01419 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMLCOEMG_01420 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PMLCOEMG_01421 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
PMLCOEMG_01422 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
PMLCOEMG_01423 5.1e-119 yvyE 3.4.13.9 S YigZ family
PMLCOEMG_01424 3e-37
PMLCOEMG_01425 2.4e-110 K WHG domain
PMLCOEMG_01426 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
PMLCOEMG_01427 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
PMLCOEMG_01428 6e-151 3.1.3.48 T Tyrosine phosphatase family
PMLCOEMG_01429 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PMLCOEMG_01431 3e-53 cvpA S Colicin V production protein
PMLCOEMG_01432 7.3e-175 EGP Sugar (and other) transporter
PMLCOEMG_01433 1.2e-18
PMLCOEMG_01434 8e-210
PMLCOEMG_01435 3.5e-136 S SLAP domain
PMLCOEMG_01436 1.3e-117 S SLAP domain
PMLCOEMG_01437 9.1e-106 S Bacteriocin helveticin-J
PMLCOEMG_01438 1.2e-44
PMLCOEMG_01439 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_01440 4e-32 E Zn peptidase
PMLCOEMG_01441 1.9e-286 clcA P chloride
PMLCOEMG_01442 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PMLCOEMG_01443 5.1e-226 N Uncharacterized conserved protein (DUF2075)
PMLCOEMG_01444 4.8e-205 pbpX1 V Beta-lactamase
PMLCOEMG_01445 0.0 L Helicase C-terminal domain protein
PMLCOEMG_01446 1.3e-273 E amino acid
PMLCOEMG_01447 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
PMLCOEMG_01450 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMLCOEMG_01451 7.6e-134 EGP Major facilitator Superfamily
PMLCOEMG_01452 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
PMLCOEMG_01453 0.0 tetP J elongation factor G
PMLCOEMG_01454 3.5e-160 yvgN C Aldo keto reductase
PMLCOEMG_01455 2e-155 P CorA-like Mg2+ transporter protein
PMLCOEMG_01456 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMLCOEMG_01457 1.7e-174 ABC-SBP S ABC transporter
PMLCOEMG_01458 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PMLCOEMG_01459 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
PMLCOEMG_01460 5.2e-248 G Major Facilitator
PMLCOEMG_01461 4.1e-18
PMLCOEMG_01462 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
PMLCOEMG_01463 1.4e-176 K AI-2E family transporter
PMLCOEMG_01464 8.6e-97 oppA E ABC transporter substrate-binding protein
PMLCOEMG_01465 1.2e-232 oppA E ABC transporter substrate-binding protein
PMLCOEMG_01466 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PMLCOEMG_01467 5.6e-294 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PMLCOEMG_01468 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PMLCOEMG_01470 2.6e-146 S Putative ABC-transporter type IV
PMLCOEMG_01472 9.9e-82 C Flavodoxin
PMLCOEMG_01473 0.0 uvrA3 L excinuclease ABC, A subunit
PMLCOEMG_01474 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PMLCOEMG_01475 2.1e-114 3.6.1.27 I Acid phosphatase homologues
PMLCOEMG_01476 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
PMLCOEMG_01477 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PMLCOEMG_01478 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
PMLCOEMG_01479 9.3e-204 pbpX1 V Beta-lactamase
PMLCOEMG_01480 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PMLCOEMG_01481 7.5e-95 S ECF-type riboflavin transporter, S component
PMLCOEMG_01482 1.3e-229 S Putative peptidoglycan binding domain
PMLCOEMG_01483 9e-83 K Acetyltransferase (GNAT) domain
PMLCOEMG_01484 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PMLCOEMG_01485 1.9e-191 yrvN L AAA C-terminal domain
PMLCOEMG_01486 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PMLCOEMG_01487 3.3e-283 treB G phosphotransferase system
PMLCOEMG_01488 1.2e-100 treR K UTRA
PMLCOEMG_01489 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PMLCOEMG_01490 2e-39 S Transglycosylase associated protein
PMLCOEMG_01491 1.5e-211 M Glycosyl hydrolases family 25
PMLCOEMG_01492 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
PMLCOEMG_01493 4.1e-67
PMLCOEMG_01494 5.4e-203 xerS L Belongs to the 'phage' integrase family
PMLCOEMG_01495 5.8e-221 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PMLCOEMG_01496 9e-60 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PMLCOEMG_01497 1.3e-159 degV S EDD domain protein, DegV family
PMLCOEMG_01498 1.1e-66
PMLCOEMG_01499 0.0 FbpA K Fibronectin-binding protein
PMLCOEMG_01500 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
PMLCOEMG_01501 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PMLCOEMG_01502 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PMLCOEMG_01503 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PMLCOEMG_01504 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PMLCOEMG_01505 5.5e-53
PMLCOEMG_01507 2.7e-34 S YSIRK type signal peptide
PMLCOEMG_01508 1.9e-110 F DNA/RNA non-specific endonuclease
PMLCOEMG_01509 2e-75 S cog cog0433
PMLCOEMG_01510 2.6e-225 V ABC transporter transmembrane region
PMLCOEMG_01511 1.3e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMLCOEMG_01512 1e-229 S Tetratricopeptide repeat protein
PMLCOEMG_01513 3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PMLCOEMG_01514 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PMLCOEMG_01515 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
PMLCOEMG_01516 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PMLCOEMG_01517 2.7e-18 M Lysin motif
PMLCOEMG_01518 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PMLCOEMG_01519 3.2e-101 3.6.1.27 I Acid phosphatase homologues
PMLCOEMG_01520 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
PMLCOEMG_01521 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PMLCOEMG_01522 8.4e-56 S Domain of unknown function (DUF4767)
PMLCOEMG_01523 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PMLCOEMG_01524 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PMLCOEMG_01525 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PMLCOEMG_01526 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PMLCOEMG_01527 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PMLCOEMG_01528 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMLCOEMG_01529 9.5e-31
PMLCOEMG_01530 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PMLCOEMG_01531 1.2e-09 S Domain of unknown function DUF87
PMLCOEMG_01532 1.2e-63 S SIR2-like domain
PMLCOEMG_01533 8.3e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PMLCOEMG_01534 2.3e-51 3.1.21.3 V Type I restriction modification DNA specificity domain
PMLCOEMG_01535 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
PMLCOEMG_01536 3.4e-42 S RloB-like protein
PMLCOEMG_01537 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
PMLCOEMG_01538 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
PMLCOEMG_01539 0.0 S SLAP domain
PMLCOEMG_01541 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
PMLCOEMG_01542 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
PMLCOEMG_01543 1.5e-239 G Bacterial extracellular solute-binding protein
PMLCOEMG_01544 5.7e-18
PMLCOEMG_01545 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PMLCOEMG_01546 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
PMLCOEMG_01547 1e-30 S cog cog1373
PMLCOEMG_01548 1.4e-15 S cog cog1373
PMLCOEMG_01549 5.2e-156 hipB K Helix-turn-helix
PMLCOEMG_01550 2.7e-151 I alpha/beta hydrolase fold
PMLCOEMG_01551 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PMLCOEMG_01552 0.0 G Belongs to the glycosyl hydrolase 31 family
PMLCOEMG_01553 8.7e-145 I alpha/beta hydrolase fold
PMLCOEMG_01554 4.9e-129 yibF S overlaps another CDS with the same product name
PMLCOEMG_01555 2.2e-202 yibE S overlaps another CDS with the same product name
PMLCOEMG_01556 1.4e-112
PMLCOEMG_01557 2.6e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PMLCOEMG_01558 6.4e-224 S Cysteine-rich secretory protein family
PMLCOEMG_01559 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLCOEMG_01560 1.3e-258 glnPH2 P ABC transporter permease
PMLCOEMG_01561 1.1e-134
PMLCOEMG_01562 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
PMLCOEMG_01563 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMLCOEMG_01564 5.6e-36
PMLCOEMG_01565 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PMLCOEMG_01566 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMLCOEMG_01568 8.1e-38 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PMLCOEMG_01569 5.2e-68 L haloacid dehalogenase-like hydrolase
PMLCOEMG_01570 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PMLCOEMG_01571 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
PMLCOEMG_01572 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
PMLCOEMG_01573 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLCOEMG_01574 1.3e-231 ulaA S PTS system sugar-specific permease component
PMLCOEMG_01575 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMLCOEMG_01576 7.1e-165 ulaG S Beta-lactamase superfamily domain
PMLCOEMG_01577 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PMLCOEMG_01578 0.0 uup S ABC transporter, ATP-binding protein
PMLCOEMG_01579 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
PMLCOEMG_01580 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PMLCOEMG_01581 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PMLCOEMG_01582 7.7e-22
PMLCOEMG_01583 9.3e-64 L PFAM IS66 Orf2 family protein
PMLCOEMG_01584 8.7e-34 S Transposase C of IS166 homeodomain
PMLCOEMG_01585 1.9e-245 L Transposase IS66 family
PMLCOEMG_01586 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PMLCOEMG_01587 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PMLCOEMG_01588 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PMLCOEMG_01589 2.2e-85 S ECF transporter, substrate-specific component
PMLCOEMG_01590 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
PMLCOEMG_01591 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PMLCOEMG_01592 1.8e-59 yabA L Involved in initiation control of chromosome replication
PMLCOEMG_01593 1.5e-155 holB 2.7.7.7 L DNA polymerase III
PMLCOEMG_01594 8.9e-53 yaaQ S Cyclic-di-AMP receptor
PMLCOEMG_01595 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PMLCOEMG_01596 1.1e-34 S Protein of unknown function (DUF2508)
PMLCOEMG_01597 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PMLCOEMG_01598 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PMLCOEMG_01599 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PMLCOEMG_01600 5.7e-106 2.4.1.58 GT8 M family 8
PMLCOEMG_01601 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMLCOEMG_01602 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PMLCOEMG_01603 1.5e-25
PMLCOEMG_01604 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
PMLCOEMG_01605 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
PMLCOEMG_01606 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PMLCOEMG_01607 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PMLCOEMG_01608 1.5e-11 GT2,GT4 M family 8
PMLCOEMG_01609 2.4e-89 L An automated process has identified a potential problem with this gene model
PMLCOEMG_01610 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
PMLCOEMG_01611 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PMLCOEMG_01612 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PMLCOEMG_01613 6.5e-154 pstA P Phosphate transport system permease protein PstA
PMLCOEMG_01614 1.4e-52 EGP Sugar (and other) transporter
PMLCOEMG_01615 1e-104
PMLCOEMG_01616 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PMLCOEMG_01617 0.0 copA 3.6.3.54 P P-type ATPase
PMLCOEMG_01618 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PMLCOEMG_01619 4.9e-58 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PMLCOEMG_01620 2.4e-36
PMLCOEMG_01623 3.7e-20
PMLCOEMG_01624 8.9e-79
PMLCOEMG_01625 9e-121
PMLCOEMG_01626 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
PMLCOEMG_01627 3.9e-186 S Putative peptidoglycan binding domain
PMLCOEMG_01628 4e-16
PMLCOEMG_01629 7.9e-92 liaI S membrane
PMLCOEMG_01630 6.6e-70 XK27_02470 K LytTr DNA-binding domain
PMLCOEMG_01631 1.2e-18 S Sugar efflux transporter for intercellular exchange
PMLCOEMG_01632 1.3e-250 dtpT U amino acid peptide transporter
PMLCOEMG_01633 0.0 pepN 3.4.11.2 E aminopeptidase
PMLCOEMG_01634 2.8e-47 lysM M LysM domain
PMLCOEMG_01635 1.3e-174
PMLCOEMG_01636 1.7e-152 mdtG EGP Major facilitator Superfamily
PMLCOEMG_01637 6.9e-47 mdtG EGP Major facilitator Superfamily
PMLCOEMG_01639 1.6e-25 K Helix-turn-helix XRE-family like proteins
PMLCOEMG_01640 1.2e-11
PMLCOEMG_01641 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
PMLCOEMG_01642 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PMLCOEMG_01643 2e-264 lctP C L-lactate permease
PMLCOEMG_01644 5e-129 znuB U ABC 3 transport family
PMLCOEMG_01645 1.6e-117 fhuC P ABC transporter
PMLCOEMG_01646 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
PMLCOEMG_01647 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
PMLCOEMG_01648 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
PMLCOEMG_01649 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PMLCOEMG_01650 1.8e-136 fruR K DeoR C terminal sensor domain
PMLCOEMG_01651 1.8e-218 natB CP ABC-2 family transporter protein
PMLCOEMG_01652 1.1e-164 natA S ABC transporter, ATP-binding protein
PMLCOEMG_01653 1.7e-67
PMLCOEMG_01654 2e-23
PMLCOEMG_01655 8.2e-31 yozG K Transcriptional regulator
PMLCOEMG_01656 3.7e-83
PMLCOEMG_01657 3e-21
PMLCOEMG_01661 2.2e-129 blpT
PMLCOEMG_01662 1.4e-107 M Transport protein ComB
PMLCOEMG_01663 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PMLCOEMG_01664 2.3e-137 L transposase, IS605 OrfB family
PMLCOEMG_01665 2.1e-28 S Peptidase propeptide and YPEB domain
PMLCOEMG_01666 2.4e-60 ypaA S Protein of unknown function (DUF1304)
PMLCOEMG_01667 2.3e-309 oppA3 E ABC transporter, substratebinding protein
PMLCOEMG_01668 9e-161 V ABC transporter transmembrane region
PMLCOEMG_01669 7e-68 V ABC transporter transmembrane region
PMLCOEMG_01670 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
PMLCOEMG_01671 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PMLCOEMG_01672 2.5e-72 S Peptidase propeptide and YPEB domain
PMLCOEMG_01673 3.4e-76 S Peptidase propeptide and YPEB domain
PMLCOEMG_01674 5.2e-187 T GHKL domain
PMLCOEMG_01675 3.1e-130 T Transcriptional regulatory protein, C terminal
PMLCOEMG_01676 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PMLCOEMG_01677 2.9e-277 V ABC transporter transmembrane region
PMLCOEMG_01678 1.9e-75 M LysM domain
PMLCOEMG_01679 1.3e-42
PMLCOEMG_01681 4.9e-35
PMLCOEMG_01682 4.5e-76 yniG EGP Major facilitator Superfamily
PMLCOEMG_01683 5.4e-237 L transposase, IS605 OrfB family
PMLCOEMG_01684 4.7e-159 D nuclear chromosome segregation
PMLCOEMG_01685 1.2e-105 G Phosphoglycerate mutase family
PMLCOEMG_01686 2.6e-89 G Histidine phosphatase superfamily (branch 1)
PMLCOEMG_01687 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
PMLCOEMG_01688 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PMLCOEMG_01690 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PMLCOEMG_01692 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PMLCOEMG_01693 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
PMLCOEMG_01694 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PMLCOEMG_01695 4.4e-144 K SIS domain
PMLCOEMG_01696 6.7e-228 slpX S SLAP domain
PMLCOEMG_01697 1.3e-22 3.6.4.12 S transposase or invertase
PMLCOEMG_01698 6.6e-11
PMLCOEMG_01699 3.2e-240 npr 1.11.1.1 C NADH oxidase
PMLCOEMG_01702 4.4e-239 oppA2 E ABC transporter, substratebinding protein
PMLCOEMG_01703 3.4e-45 oppA2 E ABC transporter, substratebinding protein
PMLCOEMG_01704 3.3e-179
PMLCOEMG_01705 4.6e-123 gntR1 K UTRA
PMLCOEMG_01706 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
PMLCOEMG_01707 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PMLCOEMG_01708 1.7e-204 csaB M Glycosyl transferases group 1
PMLCOEMG_01709 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PMLCOEMG_01710 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PMLCOEMG_01711 0.0 1.3.5.4 C FAD binding domain
PMLCOEMG_01712 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PMLCOEMG_01713 1.7e-249 yhdP S Transporter associated domain
PMLCOEMG_01714 3.9e-119 C nitroreductase
PMLCOEMG_01715 2.1e-39
PMLCOEMG_01716 4.2e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PMLCOEMG_01717 1.6e-80
PMLCOEMG_01718 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
PMLCOEMG_01719 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
PMLCOEMG_01720 5.4e-147 S hydrolase
PMLCOEMG_01721 2e-160 rssA S Phospholipase, patatin family
PMLCOEMG_01722 6.9e-186 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PMLCOEMG_01723 1.2e-94
PMLCOEMG_01724 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
PMLCOEMG_01725 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PMLCOEMG_01726 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PMLCOEMG_01727 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PMLCOEMG_01728 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
PMLCOEMG_01729 2e-163 murB 1.3.1.98 M Cell wall formation
PMLCOEMG_01730 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PMLCOEMG_01731 1.3e-129 potB P ABC transporter permease
PMLCOEMG_01732 4.8e-127 potC P ABC transporter permease
PMLCOEMG_01733 7.3e-208 potD P ABC transporter
PMLCOEMG_01734 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PMLCOEMG_01735 7.5e-172 ybbR S YbbR-like protein
PMLCOEMG_01736 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PMLCOEMG_01737 1.4e-147 S hydrolase
PMLCOEMG_01738 1.8e-75 K Penicillinase repressor
PMLCOEMG_01739 1.6e-118
PMLCOEMG_01740 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PMLCOEMG_01741 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PMLCOEMG_01742 8.3e-143 licT K CAT RNA binding domain
PMLCOEMG_01743 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
PMLCOEMG_01744 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLCOEMG_01745 1e-149 D Alpha beta
PMLCOEMG_01746 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
PMLCOEMG_01747 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
PMLCOEMG_01748 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
PMLCOEMG_01749 8.2e-36
PMLCOEMG_01750 2.2e-90 2.7.7.65 T GGDEF domain
PMLCOEMG_01751 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PMLCOEMG_01753 5.9e-310 E Amino acid permease
PMLCOEMG_01754 5.8e-100 L Helix-turn-helix domain
PMLCOEMG_01755 1.3e-160 L hmm pf00665
PMLCOEMG_01757 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PMLCOEMG_01758 6.8e-50 ylbE GM NAD(P)H-binding
PMLCOEMG_01759 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PMLCOEMG_01760 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PMLCOEMG_01761 1.7e-29 secG U Preprotein translocase
PMLCOEMG_01762 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PMLCOEMG_01763 5.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PMLCOEMG_01764 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
PMLCOEMG_01765 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
PMLCOEMG_01773 1.8e-121 L UvrD/REP helicase N-terminal domain
PMLCOEMG_01774 1.1e-103 L AAA ATPase domain
PMLCOEMG_01775 3.5e-175 S Cysteine-rich secretory protein family
PMLCOEMG_01776 1.6e-41
PMLCOEMG_01777 2.6e-118 M NlpC/P60 family
PMLCOEMG_01778 1.4e-136 M NlpC P60 family protein
PMLCOEMG_01779 5e-88 M NlpC/P60 family
PMLCOEMG_01780 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
PMLCOEMG_01781 3.9e-42
PMLCOEMG_01782 2.9e-279 S O-antigen ligase like membrane protein
PMLCOEMG_01783 3.3e-112
PMLCOEMG_01784 2.6e-76 tnpB L Putative transposase DNA-binding domain
PMLCOEMG_01785 0.0 clpE O Belongs to the ClpA ClpB family
PMLCOEMG_01786 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
PMLCOEMG_01787 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PMLCOEMG_01788 1.4e-140 hlyX S Transporter associated domain
PMLCOEMG_01789 2.7e-74
PMLCOEMG_01790 1.6e-85
PMLCOEMG_01791 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
PMLCOEMG_01792 9.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMLCOEMG_01793 5.7e-120 D Alpha beta
PMLCOEMG_01794 1.8e-38 D Alpha beta
PMLCOEMG_01795 1e-44
PMLCOEMG_01796 5.5e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PMLCOEMG_01797 4.6e-211 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PMLCOEMG_01798 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
PMLCOEMG_01799 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PMLCOEMG_01800 3.6e-163 yihY S Belongs to the UPF0761 family
PMLCOEMG_01801 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
PMLCOEMG_01802 4.1e-80 fld C Flavodoxin
PMLCOEMG_01803 7e-87 gtcA S Teichoic acid glycosylation protein
PMLCOEMG_01804 1.5e-234 L Transposase DDE domain
PMLCOEMG_01805 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PMLCOEMG_01807 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLCOEMG_01808 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
PMLCOEMG_01809 1.3e-61 M Glycosyl hydrolases family 25
PMLCOEMG_01810 2.6e-61 M Glycosyl hydrolases family 25
PMLCOEMG_01811 2.5e-226 pbuG S permease
PMLCOEMG_01812 9.7e-146 S haloacid dehalogenase-like hydrolase
PMLCOEMG_01813 2e-225 S cog cog1373
PMLCOEMG_01814 6.1e-61 K Transcriptional regulator
PMLCOEMG_01815 1.3e-94 K Transcriptional regulator
PMLCOEMG_01816 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
PMLCOEMG_01817 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
PMLCOEMG_01818 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
PMLCOEMG_01819 5.2e-08
PMLCOEMG_01820 3e-89 ntd 2.4.2.6 F Nucleoside
PMLCOEMG_01821 3.9e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMLCOEMG_01822 3.4e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
PMLCOEMG_01823 6.8e-84 uspA T universal stress protein
PMLCOEMG_01824 1.2e-150 phnD P Phosphonate ABC transporter
PMLCOEMG_01825 4.1e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PMLCOEMG_01826 1.2e-111 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
PMLCOEMG_01827 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
PMLCOEMG_01828 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
PMLCOEMG_01829 3.1e-48 S Domain of unknown function (DUF4811)
PMLCOEMG_01830 1.4e-262 lmrB EGP Major facilitator Superfamily
PMLCOEMG_01831 4.2e-77 K MerR HTH family regulatory protein
PMLCOEMG_01832 3.1e-139 S Cysteine-rich secretory protein family
PMLCOEMG_01833 4.6e-274 ycaM E amino acid
PMLCOEMG_01834 2.8e-290
PMLCOEMG_01836 2.6e-189 cggR K Putative sugar-binding domain
PMLCOEMG_01837 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PMLCOEMG_01838 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PMLCOEMG_01839 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PMLCOEMG_01840 8.8e-58 S Peptidase propeptide and YPEB domain
PMLCOEMG_01841 3.8e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PMLCOEMG_01842 7.4e-169 coaA 2.7.1.33 F Pantothenic acid kinase
PMLCOEMG_01843 4.9e-99 E GDSL-like Lipase/Acylhydrolase
PMLCOEMG_01844 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
PMLCOEMG_01845 1.1e-142 aatB ET ABC transporter substrate-binding protein
PMLCOEMG_01846 1e-105 glnQ 3.6.3.21 E ABC transporter
PMLCOEMG_01847 1.5e-107 glnP P ABC transporter permease
PMLCOEMG_01848 0.0 helD 3.6.4.12 L DNA helicase
PMLCOEMG_01849 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PMLCOEMG_01850 1.4e-126 pgm3 G Phosphoglycerate mutase family
PMLCOEMG_01851 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PMLCOEMG_01852 8.2e-85 scrR K Periplasmic binding protein domain
PMLCOEMG_01853 4.5e-239 XK27_09600 V ABC transporter, ATP-binding protein
PMLCOEMG_01854 0.0 V ABC transporter transmembrane region
PMLCOEMG_01855 1.6e-100 S ABC-type cobalt transport system, permease component
PMLCOEMG_01856 1e-246 G MFS/sugar transport protein
PMLCOEMG_01857 1e-44 udk 2.7.1.48 F Zeta toxin
PMLCOEMG_01858 3.8e-46 udk 2.7.1.48 F Zeta toxin
PMLCOEMG_01859 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLCOEMG_01860 1.2e-146 glnH ET ABC transporter substrate-binding protein
PMLCOEMG_01861 3.7e-90 gluC P ABC transporter permease
PMLCOEMG_01862 4.7e-109 glnP P ABC transporter permease
PMLCOEMG_01863 1.1e-164 S Protein of unknown function (DUF2974)
PMLCOEMG_01864 6.2e-85
PMLCOEMG_01865 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
PMLCOEMG_01866 5e-235 G Bacterial extracellular solute-binding protein
PMLCOEMG_01867 3.7e-131 gmuR K UTRA
PMLCOEMG_01868 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLCOEMG_01869 3.5e-70 S Domain of unknown function (DUF3284)
PMLCOEMG_01870 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLCOEMG_01871 4.3e-24 S SLAP domain
PMLCOEMG_01872 3.8e-24 S SLAP domain
PMLCOEMG_01874 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PMLCOEMG_01875 2.6e-181 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
PMLCOEMG_01876 8.8e-177 yjbQ P TrkA C-terminal domain protein
PMLCOEMG_01877 1.9e-113 yjbQ P TrkA C-terminal domain protein
PMLCOEMG_01878 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PMLCOEMG_01879 6e-161 S Oxidoreductase family, NAD-binding Rossmann fold
PMLCOEMG_01880 4.6e-130
PMLCOEMG_01881 2.1e-116
PMLCOEMG_01882 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PMLCOEMG_01883 1.4e-98 G Aldose 1-epimerase
PMLCOEMG_01884 2.8e-199 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PMLCOEMG_01885 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PMLCOEMG_01886 0.0 XK27_08315 M Sulfatase
PMLCOEMG_01887 2.9e-23
PMLCOEMG_01888 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMLCOEMG_01889 0.0 L AAA domain
PMLCOEMG_01890 1e-226 yhaO L Ser Thr phosphatase family protein
PMLCOEMG_01891 7.2e-56 yheA S Belongs to the UPF0342 family
PMLCOEMG_01892 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PMLCOEMG_01893 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PMLCOEMG_01894 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PMLCOEMG_01895 2.4e-89 ypmB S Protein conserved in bacteria
PMLCOEMG_01896 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PMLCOEMG_01897 1.3e-114 dnaD L DnaD domain protein
PMLCOEMG_01898 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PMLCOEMG_01899 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PMLCOEMG_01900 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PMLCOEMG_01901 1e-107 ypsA S Belongs to the UPF0398 family
PMLCOEMG_01902 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PMLCOEMG_01903 1.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PMLCOEMG_01904 1.4e-242 cpdA S Calcineurin-like phosphoesterase
PMLCOEMG_01905 3.4e-79
PMLCOEMG_01906 1.7e-78 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
PMLCOEMG_01907 2.1e-08 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
PMLCOEMG_01908 1.2e-241 S response to antibiotic
PMLCOEMG_01909 4.9e-125
PMLCOEMG_01910 0.0 3.6.3.8 P P-type ATPase
PMLCOEMG_01911 8.7e-66 2.7.1.191 G PTS system fructose IIA component
PMLCOEMG_01912 4.4e-43
PMLCOEMG_01913 5.9e-09
PMLCOEMG_01914 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
PMLCOEMG_01915 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
PMLCOEMG_01916 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
PMLCOEMG_01917 3e-48 V ABC transporter transmembrane region
PMLCOEMG_01918 5.2e-91 speG J Acetyltransferase (GNAT) domain
PMLCOEMG_01920 1.8e-104 3.2.2.20 K acetyltransferase
PMLCOEMG_01921 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)