ORF_ID e_value Gene_name EC_number CAZy COGs Description
HIFPGDGE_00001 4e-145 yfeO P Voltage gated chloride channel
HIFPGDGE_00002 4e-184 5.3.3.2 C FMN-dependent dehydrogenase
HIFPGDGE_00003 2.8e-52
HIFPGDGE_00004 3.8e-42
HIFPGDGE_00005 1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIFPGDGE_00006 7.3e-297 ybeC E amino acid
HIFPGDGE_00007 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HIFPGDGE_00008 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HIFPGDGE_00009 2.5e-39 rpmE2 J Ribosomal protein L31
HIFPGDGE_00010 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIFPGDGE_00011 1.6e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIFPGDGE_00012 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIFPGDGE_00013 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIFPGDGE_00014 3.4e-129 S (CBS) domain
HIFPGDGE_00015 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIFPGDGE_00016 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIFPGDGE_00017 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIFPGDGE_00018 7.4e-40 yabO J S4 domain protein
HIFPGDGE_00019 2e-35
HIFPGDGE_00021 3.8e-104 pncA Q Isochorismatase family
HIFPGDGE_00022 4.9e-118
HIFPGDGE_00025 3.6e-63
HIFPGDGE_00026 2.5e-26
HIFPGDGE_00027 1.1e-192 oppD P Belongs to the ABC transporter superfamily
HIFPGDGE_00028 1.5e-170 oppF P Belongs to the ABC transporter superfamily
HIFPGDGE_00029 5.7e-172 oppB P ABC transporter permease
HIFPGDGE_00030 1.2e-134 oppC P Binding-protein-dependent transport system inner membrane component
HIFPGDGE_00031 1.2e-300 oppA E ABC transporter substrate-binding protein
HIFPGDGE_00032 2.1e-308 oppA E ABC transporter substrate-binding protein
HIFPGDGE_00033 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIFPGDGE_00034 0.0 smc D Required for chromosome condensation and partitioning
HIFPGDGE_00035 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIFPGDGE_00036 2.5e-288 pipD E Dipeptidase
HIFPGDGE_00038 3.4e-23
HIFPGDGE_00039 4.1e-133 cysA V ABC transporter, ATP-binding protein
HIFPGDGE_00040 0.0 V FtsX-like permease family
HIFPGDGE_00041 2.7e-258 yfnA E amino acid
HIFPGDGE_00042 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIFPGDGE_00043 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIFPGDGE_00044 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HIFPGDGE_00045 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIFPGDGE_00046 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HIFPGDGE_00047 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIFPGDGE_00048 4.6e-213 S SLAP domain
HIFPGDGE_00049 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HIFPGDGE_00050 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
HIFPGDGE_00051 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIFPGDGE_00052 3e-38 ynzC S UPF0291 protein
HIFPGDGE_00053 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
HIFPGDGE_00054 0.0 mdlA V ABC transporter
HIFPGDGE_00055 0.0 mdlB V ABC transporter
HIFPGDGE_00056 0.0 pepO 3.4.24.71 O Peptidase family M13
HIFPGDGE_00057 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HIFPGDGE_00058 2.9e-116 plsC 2.3.1.51 I Acyltransferase
HIFPGDGE_00059 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
HIFPGDGE_00060 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HIFPGDGE_00061 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIFPGDGE_00062 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HIFPGDGE_00063 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIFPGDGE_00064 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIFPGDGE_00065 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
HIFPGDGE_00066 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HIFPGDGE_00067 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIFPGDGE_00068 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIFPGDGE_00069 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HIFPGDGE_00070 1.4e-196 nusA K Participates in both transcription termination and antitermination
HIFPGDGE_00071 8.8e-47 ylxR K Protein of unknown function (DUF448)
HIFPGDGE_00072 3.2e-47 rplGA J ribosomal protein
HIFPGDGE_00073 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIFPGDGE_00074 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIFPGDGE_00075 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIFPGDGE_00076 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HIFPGDGE_00077 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIFPGDGE_00078 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIFPGDGE_00079 0.0 dnaK O Heat shock 70 kDa protein
HIFPGDGE_00080 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIFPGDGE_00081 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIFPGDGE_00082 4.2e-180 sip L Belongs to the 'phage' integrase family
HIFPGDGE_00083 1.6e-20 S YjcQ protein
HIFPGDGE_00088 3.3e-18 S Pfam:Peptidase_M78
HIFPGDGE_00089 6.5e-23 K Cro/C1-type HTH DNA-binding domain
HIFPGDGE_00090 9.5e-12 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_00091 1.3e-81 S DNA binding
HIFPGDGE_00096 2.9e-12
HIFPGDGE_00097 4.3e-98 S AntA/AntB antirepressor
HIFPGDGE_00101 7.2e-10
HIFPGDGE_00102 1.8e-07 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_00107 6.5e-57 S Protein of unknown function (DUF1071)
HIFPGDGE_00108 2.7e-34 S Conserved phage C-terminus (Phg_2220_C)
HIFPGDGE_00109 7.1e-51 dnaC L IstB-like ATP binding protein
HIFPGDGE_00115 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
HIFPGDGE_00116 1.6e-14
HIFPGDGE_00124 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
HIFPGDGE_00125 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
HIFPGDGE_00126 1.5e-28 L Terminase small subunit
HIFPGDGE_00127 1.8e-230 S Terminase-like family
HIFPGDGE_00128 7e-142 S Protein of unknown function (DUF1073)
HIFPGDGE_00129 1e-97 S Phage Mu protein F like protein
HIFPGDGE_00130 1.1e-07 S Lysin motif
HIFPGDGE_00131 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
HIFPGDGE_00132 1.6e-58
HIFPGDGE_00133 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HIFPGDGE_00134 2.1e-30 S Protein of unknown function (DUF4054)
HIFPGDGE_00135 1.5e-75
HIFPGDGE_00136 2.9e-45
HIFPGDGE_00137 8e-57
HIFPGDGE_00138 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
HIFPGDGE_00139 4e-56
HIFPGDGE_00140 9e-27
HIFPGDGE_00142 0.0 3.4.14.13 M Phage tail tape measure protein TP901
HIFPGDGE_00143 1.2e-58 M LysM domain
HIFPGDGE_00144 1.4e-45
HIFPGDGE_00145 5.7e-104
HIFPGDGE_00146 1.2e-48
HIFPGDGE_00147 9.5e-33
HIFPGDGE_00148 1.7e-125 Z012_12235 S Baseplate J-like protein
HIFPGDGE_00149 1.1e-08
HIFPGDGE_00150 8.4e-309 E Amino acid permease
HIFPGDGE_00151 2.9e-277 V ABC transporter transmembrane region
HIFPGDGE_00152 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HIFPGDGE_00153 3.1e-130 T Transcriptional regulatory protein, C terminal
HIFPGDGE_00154 5.2e-187 T GHKL domain
HIFPGDGE_00155 3.4e-76 S Peptidase propeptide and YPEB domain
HIFPGDGE_00156 2.5e-72 S Peptidase propeptide and YPEB domain
HIFPGDGE_00157 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HIFPGDGE_00158 1.9e-64 yybA 2.3.1.57 K Transcriptional regulator
HIFPGDGE_00159 7e-68 V ABC transporter transmembrane region
HIFPGDGE_00160 9e-161 V ABC transporter transmembrane region
HIFPGDGE_00161 2.3e-309 oppA3 E ABC transporter, substratebinding protein
HIFPGDGE_00162 2.4e-60 ypaA S Protein of unknown function (DUF1304)
HIFPGDGE_00163 2.1e-28 S Peptidase propeptide and YPEB domain
HIFPGDGE_00164 7.1e-237 L transposase, IS605 OrfB family
HIFPGDGE_00165 3.3e-140 repB EP Plasmid replication protein
HIFPGDGE_00166 1.5e-77 S helix_turn_helix, Deoxyribose operon repressor
HIFPGDGE_00167 8.1e-175 ulaG S Beta-lactamase superfamily domain
HIFPGDGE_00168 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HIFPGDGE_00169 5.3e-233 ulaA S PTS system sugar-specific permease component
HIFPGDGE_00170 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HIFPGDGE_00171 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HIFPGDGE_00172 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HIFPGDGE_00173 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HIFPGDGE_00174 5.2e-68 L haloacid dehalogenase-like hydrolase
HIFPGDGE_00175 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HIFPGDGE_00176 1.4e-16 L Transposase
HIFPGDGE_00177 1.9e-12 L Transposase
HIFPGDGE_00178 2.6e-56 K Acetyltransferase (GNAT) domain
HIFPGDGE_00179 1.2e-10
HIFPGDGE_00180 2.8e-65 K LytTr DNA-binding domain
HIFPGDGE_00181 1.2e-49 S Protein of unknown function (DUF3021)
HIFPGDGE_00182 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HIFPGDGE_00183 7.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HIFPGDGE_00184 1.1e-133 S membrane transporter protein
HIFPGDGE_00185 2.2e-125 gpmB G Belongs to the phosphoglycerate mutase family
HIFPGDGE_00186 6.6e-162 czcD P cation diffusion facilitator family transporter
HIFPGDGE_00187 1.4e-23
HIFPGDGE_00188 1.7e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIFPGDGE_00189 2.4e-183 S AAA domain
HIFPGDGE_00190 7.3e-44
HIFPGDGE_00191 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
HIFPGDGE_00192 4.1e-52
HIFPGDGE_00193 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HIFPGDGE_00194 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIFPGDGE_00195 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIFPGDGE_00196 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIFPGDGE_00197 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIFPGDGE_00198 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIFPGDGE_00199 1.2e-94 sigH K Belongs to the sigma-70 factor family
HIFPGDGE_00200 1.7e-34
HIFPGDGE_00201 2.5e-286 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HIFPGDGE_00202 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIFPGDGE_00203 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIFPGDGE_00204 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIFPGDGE_00205 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HIFPGDGE_00206 1.5e-102 srtA 3.4.22.70 M sortase family
HIFPGDGE_00207 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HIFPGDGE_00208 5.9e-24
HIFPGDGE_00209 8.8e-172 M Glycosyl hydrolases family 25
HIFPGDGE_00210 2.9e-29
HIFPGDGE_00211 7.5e-17
HIFPGDGE_00213 1.1e-07
HIFPGDGE_00214 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
HIFPGDGE_00215 1.4e-38
HIFPGDGE_00217 2.7e-58 P ABC transporter
HIFPGDGE_00218 2.4e-284 V ABC-type multidrug transport system, ATPase and permease components
HIFPGDGE_00219 1.2e-247 yifK E Amino acid permease
HIFPGDGE_00220 9.1e-178 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIFPGDGE_00221 2.2e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIFPGDGE_00222 0.0 aha1 P E1-E2 ATPase
HIFPGDGE_00223 1.9e-175 F DNA/RNA non-specific endonuclease
HIFPGDGE_00224 2e-160 metQ2 P Belongs to the nlpA lipoprotein family
HIFPGDGE_00225 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIFPGDGE_00226 2e-73 metI P ABC transporter permease
HIFPGDGE_00227 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIFPGDGE_00228 1.9e-261 frdC 1.3.5.4 C FAD binding domain
HIFPGDGE_00229 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIFPGDGE_00230 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
HIFPGDGE_00231 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
HIFPGDGE_00232 2.3e-273 P Sodium:sulfate symporter transmembrane region
HIFPGDGE_00233 1.7e-153 ydjP I Alpha/beta hydrolase family
HIFPGDGE_00234 9.1e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HIFPGDGE_00235 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
HIFPGDGE_00236 4.1e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HIFPGDGE_00237 4.9e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HIFPGDGE_00238 9.3e-72 yeaL S Protein of unknown function (DUF441)
HIFPGDGE_00239 3.5e-21
HIFPGDGE_00240 3.6e-146 cbiQ P cobalt transport
HIFPGDGE_00241 0.0 ykoD P ABC transporter, ATP-binding protein
HIFPGDGE_00242 1.5e-95 S UPF0397 protein
HIFPGDGE_00243 2.9e-66 S Domain of unknown function DUF1828
HIFPGDGE_00244 5.5e-09
HIFPGDGE_00245 1.5e-50
HIFPGDGE_00246 2.6e-177 citR K Putative sugar-binding domain
HIFPGDGE_00247 6.5e-249 yjjP S Putative threonine/serine exporter
HIFPGDGE_00249 5.9e-37 M domain protein
HIFPGDGE_00250 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIFPGDGE_00251 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
HIFPGDGE_00252 8.5e-60
HIFPGDGE_00253 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIFPGDGE_00254 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIFPGDGE_00255 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HIFPGDGE_00256 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HIFPGDGE_00257 9.8e-222 patA 2.6.1.1 E Aminotransferase
HIFPGDGE_00258 0.0 dnaE 2.7.7.7 L DNA polymerase
HIFPGDGE_00259 2.3e-23 S Protein of unknown function (DUF2929)
HIFPGDGE_00260 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HIFPGDGE_00261 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HIFPGDGE_00262 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
HIFPGDGE_00263 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIFPGDGE_00264 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIFPGDGE_00265 2.2e-292 I Acyltransferase
HIFPGDGE_00266 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIFPGDGE_00267 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIFPGDGE_00268 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
HIFPGDGE_00269 1.1e-243 yfnA E Amino Acid
HIFPGDGE_00270 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIFPGDGE_00271 1.3e-148 yxeH S hydrolase
HIFPGDGE_00272 2.7e-32 S reductase
HIFPGDGE_00273 4.4e-39 S reductase
HIFPGDGE_00274 4.8e-34 S reductase
HIFPGDGE_00275 1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIFPGDGE_00276 5e-129 znuB U ABC 3 transport family
HIFPGDGE_00277 2.3e-116 fhuC P ABC transporter
HIFPGDGE_00278 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
HIFPGDGE_00279 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HIFPGDGE_00280 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HIFPGDGE_00281 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HIFPGDGE_00282 1.8e-136 fruR K DeoR C terminal sensor domain
HIFPGDGE_00283 1.8e-218 natB CP ABC-2 family transporter protein
HIFPGDGE_00284 1.1e-164 natA S ABC transporter, ATP-binding protein
HIFPGDGE_00285 1.7e-67
HIFPGDGE_00286 2e-23
HIFPGDGE_00287 8.2e-31 yozG K Transcriptional regulator
HIFPGDGE_00288 3.7e-83
HIFPGDGE_00289 3e-21
HIFPGDGE_00293 2.2e-129 blpT
HIFPGDGE_00294 1.4e-107 M Transport protein ComB
HIFPGDGE_00295 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HIFPGDGE_00296 4e-08
HIFPGDGE_00297 6.6e-56
HIFPGDGE_00298 2.7e-57
HIFPGDGE_00299 1.6e-11
HIFPGDGE_00300 8.1e-126 S PAS domain
HIFPGDGE_00301 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIFPGDGE_00302 0.0 typA T GTP-binding protein TypA
HIFPGDGE_00303 5.9e-211 ftsW D Belongs to the SEDS family
HIFPGDGE_00304 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HIFPGDGE_00305 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HIFPGDGE_00306 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIFPGDGE_00307 2.4e-187 ylbL T Belongs to the peptidase S16 family
HIFPGDGE_00308 3.1e-79 comEA L Competence protein ComEA
HIFPGDGE_00309 0.0 comEC S Competence protein ComEC
HIFPGDGE_00310 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
HIFPGDGE_00311 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
HIFPGDGE_00312 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIFPGDGE_00313 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIFPGDGE_00314 1.3e-148
HIFPGDGE_00315 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIFPGDGE_00316 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIFPGDGE_00317 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIFPGDGE_00318 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
HIFPGDGE_00319 7.8e-39 yjeM E Amino Acid
HIFPGDGE_00320 3.4e-175 yjeM E Amino Acid
HIFPGDGE_00321 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIFPGDGE_00322 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HIFPGDGE_00323 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIFPGDGE_00324 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIFPGDGE_00325 5.2e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIFPGDGE_00326 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIFPGDGE_00327 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIFPGDGE_00328 3.2e-217 aspC 2.6.1.1 E Aminotransferase
HIFPGDGE_00329 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIFPGDGE_00330 2.9e-159 pbpX1 V Beta-lactamase
HIFPGDGE_00331 4.6e-299 I Protein of unknown function (DUF2974)
HIFPGDGE_00332 3.6e-39 C FMN_bind
HIFPGDGE_00333 3.9e-82
HIFPGDGE_00334 5.4e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HIFPGDGE_00335 6.4e-90 alkD L DNA alkylation repair enzyme
HIFPGDGE_00336 5.8e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIFPGDGE_00337 3.7e-128 K UTRA domain
HIFPGDGE_00338 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HIFPGDGE_00339 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HIFPGDGE_00340 3.2e-11
HIFPGDGE_00341 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIFPGDGE_00342 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HIFPGDGE_00343 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HIFPGDGE_00344 2.2e-85 S ECF transporter, substrate-specific component
HIFPGDGE_00345 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
HIFPGDGE_00346 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIFPGDGE_00347 1.8e-59 yabA L Involved in initiation control of chromosome replication
HIFPGDGE_00348 1.5e-155 holB 2.7.7.7 L DNA polymerase III
HIFPGDGE_00349 8.9e-53 yaaQ S Cyclic-di-AMP receptor
HIFPGDGE_00350 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIFPGDGE_00351 1.1e-34 S Protein of unknown function (DUF2508)
HIFPGDGE_00352 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIFPGDGE_00353 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIFPGDGE_00354 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HIFPGDGE_00355 5.7e-106 2.4.1.58 GT8 M family 8
HIFPGDGE_00356 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIFPGDGE_00357 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIFPGDGE_00358 9e-26
HIFPGDGE_00359 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
HIFPGDGE_00360 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HIFPGDGE_00361 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIFPGDGE_00362 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIFPGDGE_00363 1.5e-11 GT2,GT4 M family 8
HIFPGDGE_00364 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
HIFPGDGE_00365 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HIFPGDGE_00366 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HIFPGDGE_00367 3.5e-71 yqeY S YqeY-like protein
HIFPGDGE_00368 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
HIFPGDGE_00369 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIFPGDGE_00370 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIFPGDGE_00371 3.8e-217 EGP Major facilitator Superfamily
HIFPGDGE_00372 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HIFPGDGE_00373 3.8e-105 vanZ V VanZ like family
HIFPGDGE_00374 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIFPGDGE_00375 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
HIFPGDGE_00376 4.4e-129 K Transcriptional regulatory protein, C terminal
HIFPGDGE_00377 7.7e-67 S SdpI/YhfL protein family
HIFPGDGE_00378 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIFPGDGE_00379 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
HIFPGDGE_00380 2.5e-89 M Protein of unknown function (DUF3737)
HIFPGDGE_00381 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HIFPGDGE_00382 2.9e-12
HIFPGDGE_00384 3.8e-15 S Domain of Unknown Function with PDB structure (DUF3850)
HIFPGDGE_00385 4.9e-208 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIFPGDGE_00386 6.5e-125 S Protein of unknown function (DUF554)
HIFPGDGE_00387 8.2e-61
HIFPGDGE_00388 5.6e-19
HIFPGDGE_00389 2.2e-102 rimL J Acetyltransferase (GNAT) domain
HIFPGDGE_00390 8.3e-58
HIFPGDGE_00391 8.9e-292 S ABC transporter
HIFPGDGE_00392 2.4e-136 thrE S Putative threonine/serine exporter
HIFPGDGE_00393 1.1e-83 S Threonine/Serine exporter, ThrE
HIFPGDGE_00394 9.1e-112 yvpB S Peptidase_C39 like family
HIFPGDGE_00395 2.5e-68
HIFPGDGE_00396 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIFPGDGE_00397 5.5e-77 nrdI F NrdI Flavodoxin like
HIFPGDGE_00398 4.7e-221 tnpB L Putative transposase DNA-binding domain
HIFPGDGE_00399 3.3e-112
HIFPGDGE_00400 2.9e-279 S O-antigen ligase like membrane protein
HIFPGDGE_00401 3.9e-42
HIFPGDGE_00402 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
HIFPGDGE_00403 5e-88 M NlpC/P60 family
HIFPGDGE_00404 1.4e-136 M NlpC P60 family protein
HIFPGDGE_00405 2.6e-118 M NlpC/P60 family
HIFPGDGE_00406 1.6e-41
HIFPGDGE_00407 3.5e-175 S Cysteine-rich secretory protein family
HIFPGDGE_00408 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIFPGDGE_00410 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIFPGDGE_00411 6.5e-146 epsB M biosynthesis protein
HIFPGDGE_00412 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HIFPGDGE_00413 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
HIFPGDGE_00414 7.6e-79
HIFPGDGE_00415 4e-242 cpdA S Calcineurin-like phosphoesterase
HIFPGDGE_00416 3.1e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HIFPGDGE_00417 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIFPGDGE_00418 1e-107 ypsA S Belongs to the UPF0398 family
HIFPGDGE_00419 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIFPGDGE_00420 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HIFPGDGE_00421 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIFPGDGE_00422 0.0 uup S ABC transporter, ATP-binding protein
HIFPGDGE_00423 7.7e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HIFPGDGE_00424 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HIFPGDGE_00425 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HIFPGDGE_00426 0.0 snf 2.7.11.1 KL domain protein
HIFPGDGE_00427 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIFPGDGE_00428 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIFPGDGE_00429 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIFPGDGE_00430 5.6e-183 K Transcriptional regulator
HIFPGDGE_00431 2.4e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
HIFPGDGE_00432 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIFPGDGE_00433 4e-57 K Helix-turn-helix domain
HIFPGDGE_00434 2.2e-142 S Belongs to the UPF0246 family
HIFPGDGE_00435 6e-140 aroD S Alpha/beta hydrolase family
HIFPGDGE_00436 3.5e-111 G phosphoglycerate mutase
HIFPGDGE_00437 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
HIFPGDGE_00438 3.3e-176 hrtB V ABC transporter permease
HIFPGDGE_00439 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HIFPGDGE_00440 1.3e-273 pipD E Dipeptidase
HIFPGDGE_00441 1.6e-61
HIFPGDGE_00442 3.3e-250 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIFPGDGE_00443 3.2e-71 S Domain of unknown function (DUF3284)
HIFPGDGE_00444 1e-300 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIFPGDGE_00445 5e-120 gmuR K UTRA
HIFPGDGE_00446 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIFPGDGE_00447 5.8e-274 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIFPGDGE_00448 9.2e-137 ypbG 2.7.1.2 GK ROK family
HIFPGDGE_00449 1.2e-85 C nitroreductase
HIFPGDGE_00450 1.7e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HIFPGDGE_00451 1.4e-232 cycA E Amino acid permease
HIFPGDGE_00452 6.2e-228 yifK E Amino acid permease
HIFPGDGE_00453 1.5e-176 S PFAM Archaeal ATPase
HIFPGDGE_00454 2.9e-139 puuD S peptidase C26
HIFPGDGE_00455 1e-230 steT_1 E amino acid
HIFPGDGE_00456 1.7e-213 1.3.5.4 C FAD binding domain
HIFPGDGE_00457 3.4e-126 1.3.5.4 C FAD binding domain
HIFPGDGE_00458 3.3e-73 3.2.1.18 GH33 M Rib/alpha-like repeat
HIFPGDGE_00459 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIFPGDGE_00461 3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HIFPGDGE_00462 2.4e-43 K Helix-turn-helix
HIFPGDGE_00463 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIFPGDGE_00464 1.4e-226 pbuX F xanthine permease
HIFPGDGE_00465 2.2e-148 msmR K AraC-like ligand binding domain
HIFPGDGE_00466 2.8e-140 msmE G Bacterial extracellular solute-binding protein
HIFPGDGE_00467 1.7e-160 scrR K Periplasmic binding protein domain
HIFPGDGE_00468 5.5e-36
HIFPGDGE_00469 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HIFPGDGE_00470 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIFPGDGE_00471 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIFPGDGE_00472 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIFPGDGE_00473 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIFPGDGE_00474 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HIFPGDGE_00475 9.5e-31
HIFPGDGE_00476 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIFPGDGE_00477 3.9e-287 clcA P chloride
HIFPGDGE_00478 4e-32 E Zn peptidase
HIFPGDGE_00479 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_00480 1.2e-44
HIFPGDGE_00481 9.1e-106 S Bacteriocin helveticin-J
HIFPGDGE_00482 1.3e-117 S SLAP domain
HIFPGDGE_00483 3.5e-136 S SLAP domain
HIFPGDGE_00484 2.8e-210
HIFPGDGE_00485 1.2e-18
HIFPGDGE_00486 7.3e-175 EGP Sugar (and other) transporter
HIFPGDGE_00487 1.4e-83 K FR47-like protein
HIFPGDGE_00488 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HIFPGDGE_00489 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIFPGDGE_00490 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIFPGDGE_00491 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIFPGDGE_00492 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIFPGDGE_00493 1.8e-62 yabR J S1 RNA binding domain
HIFPGDGE_00494 6.8e-60 divIC D Septum formation initiator
HIFPGDGE_00495 8.8e-58 S Peptidase propeptide and YPEB domain
HIFPGDGE_00496 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIFPGDGE_00497 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HIFPGDGE_00498 7.1e-98 E GDSL-like Lipase/Acylhydrolase
HIFPGDGE_00499 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
HIFPGDGE_00500 1.6e-143 aatB ET ABC transporter substrate-binding protein
HIFPGDGE_00501 1e-105 glnQ 3.6.3.21 E ABC transporter
HIFPGDGE_00502 1.5e-107 glnP P ABC transporter permease
HIFPGDGE_00503 0.0 helD 3.6.4.12 L DNA helicase
HIFPGDGE_00504 4.7e-117 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HIFPGDGE_00505 1.4e-126 pgm3 G Phosphoglycerate mutase family
HIFPGDGE_00506 9.7e-83 S An automated process has identified a potential problem with this gene model
HIFPGDGE_00507 1e-137 S Protein of unknown function (DUF3100)
HIFPGDGE_00508 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
HIFPGDGE_00509 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
HIFPGDGE_00510 0.0 oppA E ABC transporter
HIFPGDGE_00511 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
HIFPGDGE_00512 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HIFPGDGE_00513 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIFPGDGE_00514 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIFPGDGE_00515 7.2e-56 yheA S Belongs to the UPF0342 family
HIFPGDGE_00516 1.2e-230 yhaO L Ser Thr phosphatase family protein
HIFPGDGE_00517 0.0 L AAA domain
HIFPGDGE_00518 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIFPGDGE_00519 2.9e-23
HIFPGDGE_00520 2.4e-51 S Domain of unknown function DUF1829
HIFPGDGE_00521 1.1e-265
HIFPGDGE_00522 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HIFPGDGE_00523 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIFPGDGE_00524 3.9e-25
HIFPGDGE_00525 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HIFPGDGE_00526 5.7e-135 ecsA V ABC transporter, ATP-binding protein
HIFPGDGE_00527 2.9e-221 ecsB U ABC transporter
HIFPGDGE_00528 5.6e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIFPGDGE_00529 2.3e-29 S Protein of unknown function (DUF805)
HIFPGDGE_00530 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HIFPGDGE_00531 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIFPGDGE_00532 2.9e-174
HIFPGDGE_00533 1e-248 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HIFPGDGE_00534 2.5e-234 mepA V MATE efflux family protein
HIFPGDGE_00535 1.5e-172 S SLAP domain
HIFPGDGE_00536 2.5e-74 L Putative transposase DNA-binding domain
HIFPGDGE_00541 4.5e-49 Q DNA (cytosine-5-)-methyltransferase activity
HIFPGDGE_00552 2.6e-21 radC L DNA repair protein
HIFPGDGE_00553 2.7e-15 K Transcriptional regulator
HIFPGDGE_00554 5.4e-32 K Helix-turn-helix domain
HIFPGDGE_00555 5.4e-45 S ERF superfamily
HIFPGDGE_00556 1.6e-48 S Protein of unknown function (DUF1351)
HIFPGDGE_00560 1.9e-10
HIFPGDGE_00562 4e-24 S Domain of unknown function (DUF771)
HIFPGDGE_00563 4.1e-15 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_00564 2.6e-18 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_00565 5.5e-07 S Pfam:DUF955
HIFPGDGE_00567 4.1e-153 L Belongs to the 'phage' integrase family
HIFPGDGE_00569 9.8e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIFPGDGE_00570 8.3e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIFPGDGE_00571 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIFPGDGE_00572 7.6e-305 yloV S DAK2 domain fusion protein YloV
HIFPGDGE_00573 4e-57 asp S Asp23 family, cell envelope-related function
HIFPGDGE_00574 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HIFPGDGE_00575 1.4e-30
HIFPGDGE_00576 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HIFPGDGE_00577 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HIFPGDGE_00578 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIFPGDGE_00579 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HIFPGDGE_00580 1.1e-138 stp 3.1.3.16 T phosphatase
HIFPGDGE_00581 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIFPGDGE_00582 3.8e-44 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIFPGDGE_00583 1.3e-26
HIFPGDGE_00584 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HIFPGDGE_00585 5.4e-53 hipB K sequence-specific DNA binding
HIFPGDGE_00586 4.8e-42 S SnoaL-like domain
HIFPGDGE_00587 0.0 L PLD-like domain
HIFPGDGE_00588 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HIFPGDGE_00589 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HIFPGDGE_00590 1.7e-279 thrC 4.2.3.1 E Threonine synthase
HIFPGDGE_00591 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HIFPGDGE_00592 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIFPGDGE_00593 8.9e-116
HIFPGDGE_00594 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIFPGDGE_00596 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIFPGDGE_00597 2.2e-116 S Peptidase family M23
HIFPGDGE_00598 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HIFPGDGE_00599 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIFPGDGE_00600 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
HIFPGDGE_00601 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIFPGDGE_00602 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIFPGDGE_00603 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIFPGDGE_00604 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIFPGDGE_00605 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIFPGDGE_00606 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIFPGDGE_00607 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HIFPGDGE_00608 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIFPGDGE_00609 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIFPGDGE_00610 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIFPGDGE_00611 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIFPGDGE_00612 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIFPGDGE_00613 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIFPGDGE_00614 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIFPGDGE_00615 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIFPGDGE_00616 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIFPGDGE_00617 2.3e-24 rpmD J Ribosomal protein L30
HIFPGDGE_00618 2.6e-71 rplO J Binds to the 23S rRNA
HIFPGDGE_00619 9e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIFPGDGE_00620 1e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIFPGDGE_00621 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIFPGDGE_00622 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HIFPGDGE_00623 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIFPGDGE_00624 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIFPGDGE_00625 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIFPGDGE_00626 1.4e-60 rplQ J Ribosomal protein L17
HIFPGDGE_00627 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIFPGDGE_00628 3.5e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIFPGDGE_00629 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIFPGDGE_00630 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIFPGDGE_00631 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIFPGDGE_00632 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HIFPGDGE_00633 8.9e-133 L Phage integrase family
HIFPGDGE_00634 1.2e-281 phoR 2.7.13.3 T Histidine kinase
HIFPGDGE_00635 9.5e-121 T Transcriptional regulatory protein, C terminal
HIFPGDGE_00636 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
HIFPGDGE_00637 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIFPGDGE_00638 1.2e-152 pstA P Phosphate transport system permease protein PstA
HIFPGDGE_00639 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HIFPGDGE_00640 4.2e-145 pstS P Phosphate
HIFPGDGE_00641 1.3e-30
HIFPGDGE_00642 4.5e-116 oppA E ABC transporter, substratebinding protein
HIFPGDGE_00643 2.2e-50 oppA E ABC transporter, substratebinding protein
HIFPGDGE_00644 4.7e-275 ytgP S Polysaccharide biosynthesis protein
HIFPGDGE_00645 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIFPGDGE_00646 1.1e-121 3.6.1.27 I Acid phosphatase homologues
HIFPGDGE_00647 1.3e-168 K LysR substrate binding domain
HIFPGDGE_00649 4.4e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HIFPGDGE_00651 1.4e-42 1.3.5.4 C FAD binding domain
HIFPGDGE_00652 1.1e-231 ndh 1.6.99.3 C NADH dehydrogenase
HIFPGDGE_00653 2.5e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HIFPGDGE_00654 8e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIFPGDGE_00655 6.3e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HIFPGDGE_00656 6e-268 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HIFPGDGE_00657 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HIFPGDGE_00658 1.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HIFPGDGE_00659 2.2e-243 cydA 1.10.3.14 C ubiquinol oxidase
HIFPGDGE_00660 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIFPGDGE_00661 1.3e-114 dnaD L DnaD domain protein
HIFPGDGE_00662 1.7e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HIFPGDGE_00663 2.4e-89 ypmB S Protein conserved in bacteria
HIFPGDGE_00664 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HIFPGDGE_00665 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HIFPGDGE_00666 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HIFPGDGE_00667 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HIFPGDGE_00668 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HIFPGDGE_00669 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HIFPGDGE_00670 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIFPGDGE_00671 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HIFPGDGE_00672 1.7e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HIFPGDGE_00673 9.7e-169
HIFPGDGE_00674 7.5e-143
HIFPGDGE_00675 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HIFPGDGE_00676 1.4e-26
HIFPGDGE_00677 6.7e-145
HIFPGDGE_00678 5.1e-137
HIFPGDGE_00679 4.5e-141
HIFPGDGE_00680 9.6e-124 skfE V ATPases associated with a variety of cellular activities
HIFPGDGE_00681 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
HIFPGDGE_00682 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HIFPGDGE_00683 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIFPGDGE_00684 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HIFPGDGE_00685 4.8e-81 mutT 3.6.1.55 F NUDIX domain
HIFPGDGE_00686 1.4e-127 S Peptidase family M23
HIFPGDGE_00687 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIFPGDGE_00688 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIFPGDGE_00689 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HIFPGDGE_00690 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HIFPGDGE_00691 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
HIFPGDGE_00692 8e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HIFPGDGE_00693 2.3e-116 dedA S SNARE-like domain protein
HIFPGDGE_00694 3.7e-100 S Protein of unknown function (DUF1461)
HIFPGDGE_00695 6.9e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIFPGDGE_00696 8.3e-105 yutD S Protein of unknown function (DUF1027)
HIFPGDGE_00697 1.2e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HIFPGDGE_00698 4.3e-55
HIFPGDGE_00699 2.6e-266 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIFPGDGE_00700 3.2e-181 ccpA K catabolite control protein A
HIFPGDGE_00701 9.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HIFPGDGE_00702 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIFPGDGE_00703 1.1e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HIFPGDGE_00704 4.5e-39 veg S Biofilm formation stimulator VEG
HIFPGDGE_00705 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIFPGDGE_00706 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIFPGDGE_00707 3e-147 tatD L hydrolase, TatD family
HIFPGDGE_00708 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIFPGDGE_00709 1e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HIFPGDGE_00710 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HIFPGDGE_00711 2e-103 S TPM domain
HIFPGDGE_00712 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
HIFPGDGE_00713 1.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIFPGDGE_00714 1.7e-110 E Belongs to the SOS response-associated peptidase family
HIFPGDGE_00716 1e-111
HIFPGDGE_00717 2.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIFPGDGE_00718 3.9e-72 hsp O Belongs to the small heat shock protein (HSP20) family
HIFPGDGE_00719 1.4e-256 pepC 3.4.22.40 E aminopeptidase
HIFPGDGE_00720 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HIFPGDGE_00721 2.3e-198 oppD P Belongs to the ABC transporter superfamily
HIFPGDGE_00722 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIFPGDGE_00723 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIFPGDGE_00724 5.4e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIFPGDGE_00725 3.2e-10 S Domain of unknown function DUF87
HIFPGDGE_00726 1.2e-63 S SIR2-like domain
HIFPGDGE_00727 4.4e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
HIFPGDGE_00728 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
HIFPGDGE_00729 3.4e-42 S RloB-like protein
HIFPGDGE_00730 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
HIFPGDGE_00731 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HIFPGDGE_00732 0.0 S SLAP domain
HIFPGDGE_00733 2.7e-235 XK27_01810 S Calcineurin-like phosphoesterase
HIFPGDGE_00734 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HIFPGDGE_00735 5e-240 G Bacterial extracellular solute-binding protein
HIFPGDGE_00736 6.3e-17
HIFPGDGE_00737 6.5e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HIFPGDGE_00738 8.9e-101 treR K UTRA
HIFPGDGE_00739 1.5e-283 treB G phosphotransferase system
HIFPGDGE_00740 1.7e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIFPGDGE_00741 1.2e-190 yrvN L AAA C-terminal domain
HIFPGDGE_00742 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HIFPGDGE_00743 4e-83 K Acetyltransferase (GNAT) domain
HIFPGDGE_00744 5.8e-230 S Putative peptidoglycan binding domain
HIFPGDGE_00745 7.5e-95 S ECF-type riboflavin transporter, S component
HIFPGDGE_00746 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HIFPGDGE_00747 9.3e-204 pbpX1 V Beta-lactamase
HIFPGDGE_00748 4.6e-114 lacA 2.3.1.79 S Transferase hexapeptide repeat
HIFPGDGE_00749 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIFPGDGE_00750 6.8e-113 3.6.1.27 I Acid phosphatase homologues
HIFPGDGE_00751 5.2e-101 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HIFPGDGE_00752 1.9e-71 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HIFPGDGE_00753 0.0 uvrA3 L excinuclease ABC, A subunit
HIFPGDGE_00754 1.9e-138 2.4.2.3 F Phosphorylase superfamily
HIFPGDGE_00755 9e-144 2.4.2.3 F Phosphorylase superfamily
HIFPGDGE_00756 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HIFPGDGE_00757 3.2e-178 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIFPGDGE_00758 4.6e-100 3.6.1.27 I Acid phosphatase homologues
HIFPGDGE_00759 2.8e-151 yitS S Uncharacterised protein, DegV family COG1307
HIFPGDGE_00760 4.4e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIFPGDGE_00761 7.5e-91 S Domain of unknown function (DUF4767)
HIFPGDGE_00762 1.3e-159 degV S EDD domain protein, DegV family
HIFPGDGE_00763 1.1e-66
HIFPGDGE_00764 0.0 FbpA K Fibronectin-binding protein
HIFPGDGE_00765 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HIFPGDGE_00766 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIFPGDGE_00767 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIFPGDGE_00768 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIFPGDGE_00769 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HIFPGDGE_00770 5.5e-53
HIFPGDGE_00772 2.7e-34 S YSIRK type signal peptide
HIFPGDGE_00773 1.9e-110 F DNA/RNA non-specific endonuclease
HIFPGDGE_00774 2e-75 S cog cog0433
HIFPGDGE_00775 3.1e-26 E Zn peptidase
HIFPGDGE_00776 1.1e-14 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_00777 2.5e-20
HIFPGDGE_00778 1.3e-19
HIFPGDGE_00779 2.8e-34 S Domain of unknown function (DUF4417)
HIFPGDGE_00780 0.0 4.2.1.53 S Myosin-crossreactive antigen
HIFPGDGE_00781 2.3e-90 yxdD K Bacterial regulatory proteins, tetR family
HIFPGDGE_00782 9.5e-259 emrY EGP Major facilitator Superfamily
HIFPGDGE_00787 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
HIFPGDGE_00788 5.8e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIFPGDGE_00789 1.6e-199 pbpX V Beta-lactamase
HIFPGDGE_00790 1.3e-230 nhaC C Na H antiporter NhaC
HIFPGDGE_00791 4.5e-50
HIFPGDGE_00792 1.2e-105 ybhL S Belongs to the BI1 family
HIFPGDGE_00793 2.9e-66 K transcriptional regulator
HIFPGDGE_00794 7.2e-18
HIFPGDGE_00795 7.2e-172 yegS 2.7.1.107 G Lipid kinase
HIFPGDGE_00796 2e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIFPGDGE_00797 5.2e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIFPGDGE_00798 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIFPGDGE_00799 5.8e-203 camS S sex pheromone
HIFPGDGE_00800 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIFPGDGE_00801 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HIFPGDGE_00802 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HIFPGDGE_00804 4.1e-83 ydcK S Belongs to the SprT family
HIFPGDGE_00805 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HIFPGDGE_00806 1.1e-259 epsU S Polysaccharide biosynthesis protein
HIFPGDGE_00807 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HIFPGDGE_00808 0.0 pacL 3.6.3.8 P P-type ATPase
HIFPGDGE_00809 5.2e-204 tnpB L Putative transposase DNA-binding domain
HIFPGDGE_00810 4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIFPGDGE_00811 2.7e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIFPGDGE_00812 5e-204 csaB M Glycosyl transferases group 1
HIFPGDGE_00813 2.8e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HIFPGDGE_00814 1.5e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HIFPGDGE_00815 1.3e-122 gntR1 K UTRA
HIFPGDGE_00816 2.5e-179
HIFPGDGE_00817 1.6e-299 oppA2 E ABC transporter, substratebinding protein
HIFPGDGE_00820 1.1e-240 npr 1.11.1.1 C NADH oxidase
HIFPGDGE_00821 7.7e-12
HIFPGDGE_00822 1.3e-22 3.6.4.12 S transposase or invertase
HIFPGDGE_00823 7.4e-227 slpX S SLAP domain
HIFPGDGE_00824 5.4e-142 K SIS domain
HIFPGDGE_00825 1.8e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HIFPGDGE_00826 2.2e-182 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HIFPGDGE_00827 5.5e-209 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HIFPGDGE_00829 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HIFPGDGE_00831 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIFPGDGE_00832 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HIFPGDGE_00833 5.7e-89 G Histidine phosphatase superfamily (branch 1)
HIFPGDGE_00834 1.2e-105 G Phosphoglycerate mutase family
HIFPGDGE_00835 1.7e-164 D nuclear chromosome segregation
HIFPGDGE_00836 9.2e-76 M LysM domain protein
HIFPGDGE_00837 8.1e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIFPGDGE_00838 1.8e-125 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIFPGDGE_00839 6.2e-12
HIFPGDGE_00840 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HIFPGDGE_00841 2.3e-30
HIFPGDGE_00843 2.9e-69 S Iron-sulphur cluster biosynthesis
HIFPGDGE_00844 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
HIFPGDGE_00845 6.2e-59 psiE S Phosphate-starvation-inducible E
HIFPGDGE_00847 3e-37
HIFPGDGE_00848 2.4e-110 K WHG domain
HIFPGDGE_00849 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HIFPGDGE_00850 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HIFPGDGE_00851 6e-151 3.1.3.48 T Tyrosine phosphatase family
HIFPGDGE_00852 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HIFPGDGE_00854 3e-53 cvpA S Colicin V production protein
HIFPGDGE_00855 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HIFPGDGE_00856 1.5e-147 noc K Belongs to the ParB family
HIFPGDGE_00857 3.4e-138 soj D Sporulation initiation inhibitor
HIFPGDGE_00858 1.5e-153 spo0J K Belongs to the ParB family
HIFPGDGE_00859 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
HIFPGDGE_00860 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIFPGDGE_00861 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
HIFPGDGE_00862 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
HIFPGDGE_00863 7.8e-157 S reductase
HIFPGDGE_00864 2e-29
HIFPGDGE_00865 3.3e-237 L COG2963 Transposase and inactivated derivatives
HIFPGDGE_00866 4.7e-46 pspC KT PspC domain
HIFPGDGE_00868 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIFPGDGE_00869 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIFPGDGE_00870 6.7e-98 M ErfK YbiS YcfS YnhG
HIFPGDGE_00871 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HIFPGDGE_00872 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HIFPGDGE_00873 4.7e-83 yveB 2.7.4.29 I PAP2 superfamily
HIFPGDGE_00874 0.0 pepN 3.4.11.2 E aminopeptidase
HIFPGDGE_00875 2.8e-47 lysM M LysM domain
HIFPGDGE_00876 4.4e-175
HIFPGDGE_00877 2.8e-211 mdtG EGP Major facilitator Superfamily
HIFPGDGE_00878 6.7e-88 ymdB S Macro domain protein
HIFPGDGE_00880 6.7e-09
HIFPGDGE_00881 1.6e-28
HIFPGDGE_00884 1.5e-59 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_00885 3.3e-147 malG P ABC transporter permease
HIFPGDGE_00886 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
HIFPGDGE_00887 2.3e-213 malE G Bacterial extracellular solute-binding protein
HIFPGDGE_00888 3e-209 msmX P Belongs to the ABC transporter superfamily
HIFPGDGE_00889 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HIFPGDGE_00890 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HIFPGDGE_00891 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HIFPGDGE_00892 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HIFPGDGE_00893 1.3e-69 S PAS domain
HIFPGDGE_00894 9.1e-204 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIFPGDGE_00895 2e-177 yvdE K helix_turn _helix lactose operon repressor
HIFPGDGE_00896 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
HIFPGDGE_00897 1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIFPGDGE_00898 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIFPGDGE_00899 1.4e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HIFPGDGE_00900 1.9e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HIFPGDGE_00901 7.5e-214 yubA S AI-2E family transporter
HIFPGDGE_00902 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIFPGDGE_00903 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
HIFPGDGE_00904 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HIFPGDGE_00905 2.6e-222 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HIFPGDGE_00906 1.8e-234 S Peptidase M16
HIFPGDGE_00907 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HIFPGDGE_00908 2e-96 ymfM S Helix-turn-helix domain
HIFPGDGE_00909 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIFPGDGE_00910 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIFPGDGE_00911 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
HIFPGDGE_00912 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
HIFPGDGE_00913 2.5e-118 yvyE 3.4.13.9 S YigZ family
HIFPGDGE_00914 5.2e-245 comFA L Helicase C-terminal domain protein
HIFPGDGE_00915 2.9e-133 comFC S Competence protein
HIFPGDGE_00916 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIFPGDGE_00917 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIFPGDGE_00918 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIFPGDGE_00919 5.1e-17
HIFPGDGE_00920 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIFPGDGE_00921 3.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIFPGDGE_00922 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HIFPGDGE_00923 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIFPGDGE_00924 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HIFPGDGE_00925 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIFPGDGE_00926 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIFPGDGE_00927 1.1e-90 S Short repeat of unknown function (DUF308)
HIFPGDGE_00928 6.2e-165 rapZ S Displays ATPase and GTPase activities
HIFPGDGE_00929 4.3e-47 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HIFPGDGE_00930 8.9e-130 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HIFPGDGE_00931 2.1e-171 whiA K May be required for sporulation
HIFPGDGE_00932 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIFPGDGE_00933 0.0 S SH3-like domain
HIFPGDGE_00934 1.2e-188 K Periplasmic binding protein-like domain
HIFPGDGE_00935 2e-106 K Transcriptional regulator, AbiEi antitoxin
HIFPGDGE_00936 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HIFPGDGE_00937 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HIFPGDGE_00938 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HIFPGDGE_00939 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HIFPGDGE_00940 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HIFPGDGE_00941 5.4e-165 lacR K Transcriptional regulator
HIFPGDGE_00942 1e-188 lacS G Transporter
HIFPGDGE_00943 1.9e-37
HIFPGDGE_00944 7e-50
HIFPGDGE_00945 8.7e-53 S haloacid dehalogenase-like hydrolase
HIFPGDGE_00946 7.4e-86 S haloacid dehalogenase-like hydrolase
HIFPGDGE_00947 8.5e-290 V ABC-type multidrug transport system, ATPase and permease components
HIFPGDGE_00948 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
HIFPGDGE_00949 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HIFPGDGE_00950 8.5e-178 I Carboxylesterase family
HIFPGDGE_00952 1e-205 M Glycosyl hydrolases family 25
HIFPGDGE_00953 2.8e-157 cinI S Serine hydrolase (FSH1)
HIFPGDGE_00954 4.3e-298 S Predicted membrane protein (DUF2207)
HIFPGDGE_00955 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HIFPGDGE_00957 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
HIFPGDGE_00958 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIFPGDGE_00959 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HIFPGDGE_00960 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HIFPGDGE_00961 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HIFPGDGE_00962 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIFPGDGE_00963 3.4e-71 yqhY S Asp23 family, cell envelope-related function
HIFPGDGE_00964 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIFPGDGE_00965 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIFPGDGE_00966 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIFPGDGE_00967 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIFPGDGE_00968 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIFPGDGE_00969 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HIFPGDGE_00970 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
HIFPGDGE_00971 1.1e-77 6.3.3.2 S ASCH
HIFPGDGE_00972 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HIFPGDGE_00973 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIFPGDGE_00974 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIFPGDGE_00975 3.4e-100 2.7.6.5 T Region found in RelA / SpoT proteins
HIFPGDGE_00976 3.2e-105 K response regulator
HIFPGDGE_00977 1.1e-103 sptS 2.7.13.3 T Histidine kinase
HIFPGDGE_00978 2.6e-103 sptS 2.7.13.3 T Histidine kinase
HIFPGDGE_00979 7.2e-209 EGP Major facilitator Superfamily
HIFPGDGE_00980 2.3e-69 O OsmC-like protein
HIFPGDGE_00981 2.2e-85 S Protein of unknown function (DUF805)
HIFPGDGE_00982 2.2e-78
HIFPGDGE_00983 3.1e-93
HIFPGDGE_00984 9.9e-180
HIFPGDGE_00985 5.8e-83 S Fic/DOC family
HIFPGDGE_00986 3.3e-275 yjeM E Amino Acid
HIFPGDGE_00987 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIFPGDGE_00988 3.9e-12 tetP J elongation factor G
HIFPGDGE_00989 1.2e-160 yvgN C Aldo keto reductase
HIFPGDGE_00990 2e-155 P CorA-like Mg2+ transporter protein
HIFPGDGE_00991 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HIFPGDGE_00992 1.7e-174 ABC-SBP S ABC transporter
HIFPGDGE_00993 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HIFPGDGE_00994 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
HIFPGDGE_00995 5.2e-248 G Major Facilitator
HIFPGDGE_00996 4.1e-18
HIFPGDGE_00997 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HIFPGDGE_00998 4.1e-176 K AI-2E family transporter
HIFPGDGE_00999 1e-108 oppA E ABC transporter substrate-binding protein
HIFPGDGE_01000 9.2e-211 oppA E ABC transporter substrate-binding protein
HIFPGDGE_01001 5.2e-117 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIFPGDGE_01002 0.0 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HIFPGDGE_01003 3.8e-27 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HIFPGDGE_01005 2.6e-146 S Putative ABC-transporter type IV
HIFPGDGE_01006 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
HIFPGDGE_01007 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIFPGDGE_01008 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIFPGDGE_01009 2.8e-157 pstS P Phosphate
HIFPGDGE_01010 1.9e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HIFPGDGE_01011 6.5e-154 pstA P Phosphate transport system permease protein PstA
HIFPGDGE_01012 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIFPGDGE_01013 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIFPGDGE_01014 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
HIFPGDGE_01015 1.8e-163
HIFPGDGE_01016 7.8e-26 K Acetyltransferase (GNAT) domain
HIFPGDGE_01018 0.0 ydgH S MMPL family
HIFPGDGE_01019 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
HIFPGDGE_01020 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
HIFPGDGE_01021 1.8e-154 corA P CorA-like Mg2+ transporter protein
HIFPGDGE_01022 2.3e-240 G Bacterial extracellular solute-binding protein
HIFPGDGE_01023 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HIFPGDGE_01024 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HIFPGDGE_01025 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
HIFPGDGE_01026 1.9e-203 malK P ATPases associated with a variety of cellular activities
HIFPGDGE_01027 1.3e-281 pipD E Dipeptidase
HIFPGDGE_01028 1.9e-158 endA F DNA RNA non-specific endonuclease
HIFPGDGE_01029 8e-182 dnaQ 2.7.7.7 L EXOIII
HIFPGDGE_01030 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HIFPGDGE_01031 3e-116 yviA S Protein of unknown function (DUF421)
HIFPGDGE_01032 1.1e-56 S Protein of unknown function (DUF3290)
HIFPGDGE_01034 1.7e-28 mloB K Putative ATP-dependent DNA helicase recG C-terminal
HIFPGDGE_01035 1.3e-247 lctP C L-lactate permease
HIFPGDGE_01036 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIFPGDGE_01037 3.5e-32 ykzG S Belongs to the UPF0356 family
HIFPGDGE_01038 7.9e-210 S Bacterial protein of unknown function (DUF871)
HIFPGDGE_01039 2.3e-43 ybhL S Belongs to the BI1 family
HIFPGDGE_01041 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIFPGDGE_01042 1.1e-76 2.7.7.65 T GGDEF domain
HIFPGDGE_01043 8.2e-36
HIFPGDGE_01044 1.6e-116 ica2 GT2 M Glycosyl transferase family group 2
HIFPGDGE_01045 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HIFPGDGE_01046 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HIFPGDGE_01047 1e-149 D Alpha beta
HIFPGDGE_01048 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIFPGDGE_01049 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIFPGDGE_01050 8.3e-143 licT K CAT RNA binding domain
HIFPGDGE_01051 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HIFPGDGE_01052 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIFPGDGE_01053 1.6e-118
HIFPGDGE_01054 3e-75 K Penicillinase repressor
HIFPGDGE_01055 1.4e-147 S hydrolase
HIFPGDGE_01056 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIFPGDGE_01057 4.4e-172 ybbR S YbbR-like protein
HIFPGDGE_01058 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIFPGDGE_01059 7.3e-208 potD P ABC transporter
HIFPGDGE_01060 4.8e-127 potC P ABC transporter permease
HIFPGDGE_01061 1.9e-128 potB P ABC transporter permease
HIFPGDGE_01062 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HIFPGDGE_01063 2e-163 murB 1.3.1.98 M Cell wall formation
HIFPGDGE_01064 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
HIFPGDGE_01065 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HIFPGDGE_01066 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HIFPGDGE_01067 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIFPGDGE_01068 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HIFPGDGE_01069 1.2e-94
HIFPGDGE_01070 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
HIFPGDGE_01071 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIFPGDGE_01072 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HIFPGDGE_01073 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIFPGDGE_01074 2.6e-189 cggR K Putative sugar-binding domain
HIFPGDGE_01076 9.2e-289
HIFPGDGE_01077 6.6e-273 ycaM E amino acid
HIFPGDGE_01078 4.7e-140 S Cysteine-rich secretory protein family
HIFPGDGE_01079 9.9e-33 S Protein of unknown function (DUF3021)
HIFPGDGE_01080 2.5e-45 K LytTr DNA-binding domain
HIFPGDGE_01081 4.7e-93 cylB V ABC-2 type transporter
HIFPGDGE_01082 4.7e-117 cylA V ABC transporter
HIFPGDGE_01083 3.2e-77 K MerR HTH family regulatory protein
HIFPGDGE_01084 1.8e-262 lmrB EGP Major facilitator Superfamily
HIFPGDGE_01085 1.6e-94 S Domain of unknown function (DUF4811)
HIFPGDGE_01086 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
HIFPGDGE_01087 1.1e-90 ybbL S ABC transporter, ATP-binding protein
HIFPGDGE_01088 5e-84 L Putative transposase DNA-binding domain
HIFPGDGE_01089 1.4e-83 L Resolvase, N-terminal
HIFPGDGE_01090 1.2e-157 M Peptidase family M1 domain
HIFPGDGE_01091 0.0 tetP J elongation factor G
HIFPGDGE_01092 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
HIFPGDGE_01093 2.2e-133 EGP Major facilitator Superfamily
HIFPGDGE_01094 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIFPGDGE_01097 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HIFPGDGE_01098 1.3e-273 E amino acid
HIFPGDGE_01099 0.0 L Helicase C-terminal domain protein
HIFPGDGE_01100 1.5e-203 pbpX1 V Beta-lactamase
HIFPGDGE_01101 5.1e-226 N Uncharacterized conserved protein (DUF2075)
HIFPGDGE_01102 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIFPGDGE_01103 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIFPGDGE_01104 7.8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIFPGDGE_01105 2.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIFPGDGE_01106 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIFPGDGE_01107 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HIFPGDGE_01108 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIFPGDGE_01109 1.6e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIFPGDGE_01110 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HIFPGDGE_01111 2.2e-250 lctP C L-lactate permease
HIFPGDGE_01112 0.0 UW LPXTG-motif cell wall anchor domain protein
HIFPGDGE_01113 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
HIFPGDGE_01114 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
HIFPGDGE_01115 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIFPGDGE_01116 7.5e-100 J Acetyltransferase (GNAT) domain
HIFPGDGE_01117 1.4e-110 yjbF S SNARE associated Golgi protein
HIFPGDGE_01118 2.7e-151 I alpha/beta hydrolase fold
HIFPGDGE_01119 5.2e-156 hipB K Helix-turn-helix
HIFPGDGE_01120 1.4e-15 S cog cog1373
HIFPGDGE_01121 1e-30 S cog cog1373
HIFPGDGE_01122 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
HIFPGDGE_01123 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HIFPGDGE_01124 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
HIFPGDGE_01125 8.9e-276 V ABC-type multidrug transport system, ATPase and permease components
HIFPGDGE_01126 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HIFPGDGE_01127 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
HIFPGDGE_01128 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
HIFPGDGE_01129 5.9e-09
HIFPGDGE_01130 4.4e-43
HIFPGDGE_01131 8.7e-66 2.7.1.191 G PTS system fructose IIA component
HIFPGDGE_01132 0.0 3.6.3.8 P P-type ATPase
HIFPGDGE_01133 4.9e-125
HIFPGDGE_01134 1.2e-241 S response to antibiotic
HIFPGDGE_01135 1.1e-08 S CAAX amino terminal protease
HIFPGDGE_01136 6.1e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIFPGDGE_01137 1.4e-214 2.1.1.14 E methionine synthase, vitamin-B12 independent
HIFPGDGE_01138 8e-10
HIFPGDGE_01139 2.4e-27 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_01142 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIFPGDGE_01143 3.5e-101 ylbE GM NAD(P)H-binding
HIFPGDGE_01144 5.8e-94 S VanZ like family
HIFPGDGE_01145 8.9e-133 yebC K Transcriptional regulatory protein
HIFPGDGE_01146 1.7e-179 comGA NU Type II IV secretion system protein
HIFPGDGE_01147 1.7e-171 comGB NU type II secretion system
HIFPGDGE_01148 3.1e-43 comGC U competence protein ComGC
HIFPGDGE_01149 7.4e-71
HIFPGDGE_01150 8.6e-41
HIFPGDGE_01151 9.4e-76 comGF U Putative Competence protein ComGF
HIFPGDGE_01152 1.6e-21
HIFPGDGE_01153 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
HIFPGDGE_01154 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIFPGDGE_01156 1.4e-153 L Belongs to the 'phage' integrase family
HIFPGDGE_01157 5e-08 S Pfam:DUF955
HIFPGDGE_01158 1.2e-23 K Helix-turn-helix domain
HIFPGDGE_01159 9e-22 XK27_07105 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_01160 2.6e-31 K Helix-turn-helix domain
HIFPGDGE_01162 4.1e-09 S Arc-like DNA binding domain
HIFPGDGE_01164 9e-21 K Conserved phage C-terminus (Phg_2220_C)
HIFPGDGE_01165 1e-25 S Domain of unknown function (DUF771)
HIFPGDGE_01172 9.3e-86
HIFPGDGE_01173 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIFPGDGE_01174 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
HIFPGDGE_01175 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIFPGDGE_01176 2.2e-139 ypuA S Protein of unknown function (DUF1002)
HIFPGDGE_01177 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
HIFPGDGE_01178 7.3e-126 S Alpha/beta hydrolase family
HIFPGDGE_01179 1.4e-140 L An automated process has identified a potential problem with this gene model
HIFPGDGE_01180 5.6e-36
HIFPGDGE_01181 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIFPGDGE_01182 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
HIFPGDGE_01183 2.8e-135
HIFPGDGE_01184 1.3e-258 glnPH2 P ABC transporter permease
HIFPGDGE_01185 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIFPGDGE_01186 6.4e-224 S Cysteine-rich secretory protein family
HIFPGDGE_01187 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HIFPGDGE_01188 1.4e-112
HIFPGDGE_01189 2.2e-202 yibE S overlaps another CDS with the same product name
HIFPGDGE_01190 4.9e-129 yibF S overlaps another CDS with the same product name
HIFPGDGE_01191 1.9e-144 I alpha/beta hydrolase fold
HIFPGDGE_01192 0.0 G Belongs to the glycosyl hydrolase 31 family
HIFPGDGE_01193 1e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HIFPGDGE_01194 1.5e-102 GM NmrA-like family
HIFPGDGE_01195 6.2e-13 K FCD
HIFPGDGE_01196 4.7e-26 K FCD
HIFPGDGE_01197 1.6e-60 clcA P chloride
HIFPGDGE_01198 1.8e-54 clcA P chloride
HIFPGDGE_01199 2e-57 clcA P chloride
HIFPGDGE_01200 1.1e-115 L PFAM Integrase catalytic
HIFPGDGE_01201 0.0 clpE O Belongs to the ClpA ClpB family
HIFPGDGE_01202 5.3e-26
HIFPGDGE_01203 8.5e-41 ptsH G phosphocarrier protein HPR
HIFPGDGE_01204 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIFPGDGE_01205 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIFPGDGE_01206 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HIFPGDGE_01207 2.9e-159 coiA 3.6.4.12 S Competence protein
HIFPGDGE_01208 4.6e-114 yjbH Q Thioredoxin
HIFPGDGE_01209 5.2e-110 yjbK S CYTH
HIFPGDGE_01210 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HIFPGDGE_01211 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIFPGDGE_01212 5.6e-115 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIFPGDGE_01213 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HIFPGDGE_01214 4.2e-92 S SNARE associated Golgi protein
HIFPGDGE_01215 8.6e-82 yxaM EGP Major facilitator Superfamily
HIFPGDGE_01216 5.2e-69 yxaM EGP Major facilitator Superfamily
HIFPGDGE_01217 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
HIFPGDGE_01218 1e-79 S AAA domain
HIFPGDGE_01219 3.3e-61 3.6.1.55 F NUDIX domain
HIFPGDGE_01220 1e-48 S Metal binding domain of Ada
HIFPGDGE_01221 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HIFPGDGE_01222 9e-137 lysR5 K LysR substrate binding domain
HIFPGDGE_01223 8.8e-234 arcA 3.5.3.6 E Arginine
HIFPGDGE_01224 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIFPGDGE_01225 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
HIFPGDGE_01226 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HIFPGDGE_01227 2.3e-215 S Sterol carrier protein domain
HIFPGDGE_01228 1e-20
HIFPGDGE_01229 2.4e-107 K LysR substrate binding domain
HIFPGDGE_01230 9e-98
HIFPGDGE_01231 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HIFPGDGE_01232 1.4e-94
HIFPGDGE_01233 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIFPGDGE_01234 9.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIFPGDGE_01235 1.1e-12 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HIFPGDGE_01236 1.2e-116 mmuP E amino acid
HIFPGDGE_01237 3.2e-272 pepV 3.5.1.18 E dipeptidase PepV
HIFPGDGE_01238 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HIFPGDGE_01239 3.2e-283 E Amino acid permease
HIFPGDGE_01240 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HIFPGDGE_01241 1.5e-244 ynbB 4.4.1.1 P aluminum resistance
HIFPGDGE_01242 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HIFPGDGE_01243 9.9e-82 C Flavodoxin
HIFPGDGE_01244 2.1e-45 S PFAM Archaeal ATPase
HIFPGDGE_01246 2.4e-57 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HIFPGDGE_01247 5.9e-45
HIFPGDGE_01249 5.5e-30
HIFPGDGE_01250 1.1e-40 S Protein of unknown function (DUF2922)
HIFPGDGE_01251 1.1e-120 S SLAP domain
HIFPGDGE_01252 2.1e-53 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HIFPGDGE_01253 7.3e-25
HIFPGDGE_01254 3.6e-77 K DNA-templated transcription, initiation
HIFPGDGE_01255 2.7e-43
HIFPGDGE_01256 6.3e-100 S SLAP domain
HIFPGDGE_01258 4.1e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIFPGDGE_01259 6.5e-180 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HIFPGDGE_01260 0.0 yjbQ P TrkA C-terminal domain protein
HIFPGDGE_01261 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HIFPGDGE_01262 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
HIFPGDGE_01263 4.6e-130
HIFPGDGE_01264 7.1e-117
HIFPGDGE_01265 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIFPGDGE_01266 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
HIFPGDGE_01267 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HIFPGDGE_01268 1.4e-140 hlyX S Transporter associated domain
HIFPGDGE_01269 2.7e-74
HIFPGDGE_01270 1.6e-85
HIFPGDGE_01271 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HIFPGDGE_01272 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIFPGDGE_01273 1.4e-118 D Alpha beta
HIFPGDGE_01274 1.8e-38 D Alpha beta
HIFPGDGE_01275 9.4e-46
HIFPGDGE_01276 8.7e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HIFPGDGE_01277 1.7e-129 manY G PTS system
HIFPGDGE_01278 1e-173 manN G system, mannose fructose sorbose family IID component
HIFPGDGE_01279 9.9e-64 manO S Domain of unknown function (DUF956)
HIFPGDGE_01280 1.1e-158 K Transcriptional regulator
HIFPGDGE_01281 9.9e-86 maa S transferase hexapeptide repeat
HIFPGDGE_01282 1.6e-244 cycA E Amino acid permease
HIFPGDGE_01283 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HIFPGDGE_01284 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIFPGDGE_01285 0.0 mtlR K Mga helix-turn-helix domain
HIFPGDGE_01286 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HIFPGDGE_01287 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIFPGDGE_01288 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HIFPGDGE_01289 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
HIFPGDGE_01290 2.1e-79 4.1.1.44 S Carboxymuconolactone decarboxylase family
HIFPGDGE_01291 2.1e-32
HIFPGDGE_01292 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HIFPGDGE_01293 2.3e-156 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_01294 3.9e-298 V ABC transporter transmembrane region
HIFPGDGE_01295 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HIFPGDGE_01296 0.0 S TerB-C domain
HIFPGDGE_01297 3.5e-244 P P-loop Domain of unknown function (DUF2791)
HIFPGDGE_01298 0.0 lhr L DEAD DEAH box helicase
HIFPGDGE_01299 1.4e-60
HIFPGDGE_01300 4.3e-228 amtB P ammonium transporter
HIFPGDGE_01301 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HIFPGDGE_01305 1.9e-50
HIFPGDGE_01306 3.3e-35
HIFPGDGE_01307 2e-11
HIFPGDGE_01308 5.9e-126 Z012_12235 S Baseplate J-like protein
HIFPGDGE_01309 1.4e-31
HIFPGDGE_01310 2.8e-48
HIFPGDGE_01311 5.9e-117
HIFPGDGE_01312 7.9e-38
HIFPGDGE_01313 4.3e-53 M LysM domain
HIFPGDGE_01314 7.2e-235 3.4.14.13 M Phage tail tape measure protein TP901
HIFPGDGE_01316 1.1e-08
HIFPGDGE_01317 9.3e-29
HIFPGDGE_01318 5.9e-103 Z012_02110 S Protein of unknown function (DUF3383)
HIFPGDGE_01319 3.3e-31
HIFPGDGE_01320 2.1e-25
HIFPGDGE_01321 3.4e-30
HIFPGDGE_01322 9.2e-20 S Protein of unknown function (DUF4054)
HIFPGDGE_01323 5.3e-93 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HIFPGDGE_01324 5.3e-34
HIFPGDGE_01325 1.8e-58 S Uncharacterized protein conserved in bacteria (DUF2213)
HIFPGDGE_01326 1.3e-12 S Lysin motif
HIFPGDGE_01327 1.3e-47 S Phage Mu protein F like protein
HIFPGDGE_01328 1.4e-134 S Protein of unknown function (DUF1073)
HIFPGDGE_01329 1.1e-217 S Terminase-like family
HIFPGDGE_01338 7.1e-15
HIFPGDGE_01340 1.2e-37 S VRR_NUC
HIFPGDGE_01349 7.1e-98 L Helix-turn-helix domain
HIFPGDGE_01350 1.2e-135 S ERF superfamily
HIFPGDGE_01351 4.2e-129 S Protein of unknown function (DUF1351)
HIFPGDGE_01352 4.6e-45
HIFPGDGE_01354 5.5e-18
HIFPGDGE_01355 1.8e-31 S Helix-turn-helix domain
HIFPGDGE_01361 9.2e-93 S DNA binding
HIFPGDGE_01362 6.1e-18 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_01363 1.2e-22 K Cro/C1-type HTH DNA-binding domain
HIFPGDGE_01364 3.7e-12 E Zn peptidase
HIFPGDGE_01366 6.2e-12
HIFPGDGE_01367 2.6e-94 sip L Belongs to the 'phage' integrase family
HIFPGDGE_01368 6.4e-09 dps P Belongs to the Dps family
HIFPGDGE_01369 1.2e-30 copZ C Heavy-metal-associated domain
HIFPGDGE_01370 1e-284 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HIFPGDGE_01371 1.9e-30 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HIFPGDGE_01372 6.3e-26 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HIFPGDGE_01373 7.3e-173 MA20_14895 S Conserved hypothetical protein 698
HIFPGDGE_01375 2.4e-128 S cog cog1373
HIFPGDGE_01376 1.4e-109 yniG EGP Major facilitator Superfamily
HIFPGDGE_01377 5.4e-237 L transposase, IS605 OrfB family
HIFPGDGE_01378 4.5e-76 yniG EGP Major facilitator Superfamily
HIFPGDGE_01379 3.5e-29
HIFPGDGE_01381 1.3e-42
HIFPGDGE_01382 1.9e-75 M LysM domain
HIFPGDGE_01383 1.1e-71 yphH S Cupin domain
HIFPGDGE_01384 1.3e-07 S Protein of unknown function (DUF3021)
HIFPGDGE_01385 3.4e-62 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIFPGDGE_01386 1.4e-212 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
HIFPGDGE_01387 3.9e-47
HIFPGDGE_01388 3.2e-65 K HxlR family
HIFPGDGE_01389 0.0 L Plasmid pRiA4b ORF-3-like protein
HIFPGDGE_01390 1.8e-243 brnQ U Component of the transport system for branched-chain amino acids
HIFPGDGE_01391 7.4e-120 3.6.1.55 F NUDIX domain
HIFPGDGE_01392 2.6e-112 ltrA S Bacterial low temperature requirement A protein (LtrA)
HIFPGDGE_01395 1.9e-156 S Type III restriction enzyme, res subunit
HIFPGDGE_01396 2.4e-169 S Domain of unknown function (DUF3440)
HIFPGDGE_01397 1.2e-89 S N-methyltransferase activity
HIFPGDGE_01399 5.7e-166 psaA P Belongs to the bacterial solute-binding protein 9 family
HIFPGDGE_01402 1.6e-219 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIFPGDGE_01403 1.5e-259 qacA EGP Major facilitator Superfamily
HIFPGDGE_01404 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIFPGDGE_01405 1.3e-141 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HIFPGDGE_01406 1.4e-183 yfeW 3.4.16.4 V Beta-lactamase
HIFPGDGE_01407 3.1e-187 S Bacterial protein of unknown function (DUF871)
HIFPGDGE_01408 4.5e-144 ybbH_2 K rpiR family
HIFPGDGE_01409 5.9e-300 L Transposase
HIFPGDGE_01410 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
HIFPGDGE_01411 9.1e-54 papP P ABC transporter, permease protein
HIFPGDGE_01412 5.3e-116 P ABC transporter permease
HIFPGDGE_01413 1.5e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIFPGDGE_01414 1e-156 cjaA ET ABC transporter substrate-binding protein
HIFPGDGE_01415 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIFPGDGE_01416 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIFPGDGE_01417 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIFPGDGE_01418 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HIFPGDGE_01419 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
HIFPGDGE_01420 1.9e-25
HIFPGDGE_01421 0.0 mco Q Multicopper oxidase
HIFPGDGE_01422 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HIFPGDGE_01425 7e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIFPGDGE_01426 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIFPGDGE_01427 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIFPGDGE_01428 7.3e-21 hicA S HicA toxin of bacterial toxin-antitoxin,
HIFPGDGE_01429 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
HIFPGDGE_01430 3.6e-163 yihY S Belongs to the UPF0761 family
HIFPGDGE_01431 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIFPGDGE_01432 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HIFPGDGE_01433 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HIFPGDGE_01434 8.2e-85 scrR K Periplasmic binding protein domain
HIFPGDGE_01435 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HIFPGDGE_01436 9.7e-65 yagE E amino acid
HIFPGDGE_01437 8.4e-128 yagE E Amino acid permease
HIFPGDGE_01438 4.3e-86 3.4.21.96 S SLAP domain
HIFPGDGE_01439 5e-104 L Belongs to the 'phage' integrase family
HIFPGDGE_01442 3.2e-50 S Short C-terminal domain
HIFPGDGE_01443 1.7e-68 3.4.21.88 K Peptidase S24-like
HIFPGDGE_01444 2.3e-10 K Helix-turn-helix XRE-family like proteins
HIFPGDGE_01452 5.5e-30 L Psort location Cytoplasmic, score
HIFPGDGE_01458 2.2e-10
HIFPGDGE_01463 2.8e-19 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HIFPGDGE_01464 6.5e-87 K GNAT family
HIFPGDGE_01465 3.9e-201 XK27_00915 C Luciferase-like monooxygenase
HIFPGDGE_01466 2.8e-100 S ECF transporter, substrate-specific component
HIFPGDGE_01467 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HIFPGDGE_01468 0.0 macB_3 V ABC transporter, ATP-binding protein
HIFPGDGE_01469 1.6e-194 S DUF218 domain
HIFPGDGE_01470 2.7e-120 S CAAX protease self-immunity
HIFPGDGE_01471 3e-111 ropB K Transcriptional regulator
HIFPGDGE_01472 4.2e-154 EGP Major facilitator Superfamily
HIFPGDGE_01473 5.4e-51
HIFPGDGE_01474 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
HIFPGDGE_01475 4.1e-276 V ABC transporter transmembrane region
HIFPGDGE_01476 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HIFPGDGE_01477 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HIFPGDGE_01478 2.8e-205 napA P Sodium/hydrogen exchanger family
HIFPGDGE_01479 0.0 cadA P P-type ATPase
HIFPGDGE_01480 1.5e-80 ykuL S (CBS) domain
HIFPGDGE_01481 1e-207 ywhK S Membrane
HIFPGDGE_01482 4.1e-44
HIFPGDGE_01483 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
HIFPGDGE_01484 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIFPGDGE_01485 8.6e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
HIFPGDGE_01486 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIFPGDGE_01487 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIFPGDGE_01488 7.6e-177 pbpX2 V Beta-lactamase
HIFPGDGE_01489 2.3e-133 S Protein of unknown function (DUF975)
HIFPGDGE_01490 2.7e-137 lysA2 M Glycosyl hydrolases family 25
HIFPGDGE_01491 7.9e-291 ytgP S Polysaccharide biosynthesis protein
HIFPGDGE_01492 1.9e-36
HIFPGDGE_01493 0.0 XK27_06780 V ABC transporter permease
HIFPGDGE_01494 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
HIFPGDGE_01495 3.1e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIFPGDGE_01496 2.6e-166 S Alpha/beta hydrolase of unknown function (DUF915)
HIFPGDGE_01497 0.0 clpE O AAA domain (Cdc48 subfamily)
HIFPGDGE_01498 1.2e-145 V ABC transporter, ATP-binding protein
HIFPGDGE_01499 4.2e-144 V ABC transporter, ATP-binding protein
HIFPGDGE_01500 0.0 V ABC transporter
HIFPGDGE_01502 9.6e-121 K response regulator
HIFPGDGE_01503 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HIFPGDGE_01504 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIFPGDGE_01505 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HIFPGDGE_01506 1.4e-53 S Enterocin A Immunity
HIFPGDGE_01507 2.5e-33
HIFPGDGE_01508 9.5e-26
HIFPGDGE_01509 1e-24
HIFPGDGE_01510 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HIFPGDGE_01511 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HIFPGDGE_01512 2.1e-255 S Archaea bacterial proteins of unknown function
HIFPGDGE_01513 1.2e-16
HIFPGDGE_01514 4.4e-138 2.7.13.3 T GHKL domain
HIFPGDGE_01515 1.2e-127 K LytTr DNA-binding domain
HIFPGDGE_01516 6.1e-269 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HIFPGDGE_01517 1.9e-237 brnQ U Component of the transport system for branched-chain amino acids
HIFPGDGE_01518 2.8e-24 S Alpha beta hydrolase
HIFPGDGE_01519 1.4e-273 lsa S ABC transporter
HIFPGDGE_01520 3.3e-194 ampC V Beta-lactamase
HIFPGDGE_01523 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HIFPGDGE_01524 1.3e-113 tdk 2.7.1.21 F thymidine kinase
HIFPGDGE_01525 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIFPGDGE_01526 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIFPGDGE_01527 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIFPGDGE_01528 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIFPGDGE_01529 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HIFPGDGE_01530 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIFPGDGE_01531 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIFPGDGE_01532 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIFPGDGE_01533 2.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIFPGDGE_01534 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIFPGDGE_01535 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIFPGDGE_01536 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HIFPGDGE_01537 2e-30 ywzB S Protein of unknown function (DUF1146)
HIFPGDGE_01538 1.2e-177 mbl D Cell shape determining protein MreB Mrl
HIFPGDGE_01539 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HIFPGDGE_01540 3.3e-33 S Protein of unknown function (DUF2969)
HIFPGDGE_01541 1.4e-215 rodA D Belongs to the SEDS family
HIFPGDGE_01542 2.3e-78 usp6 T universal stress protein
HIFPGDGE_01543 8.4e-39
HIFPGDGE_01544 2.2e-238 rarA L recombination factor protein RarA
HIFPGDGE_01545 1.3e-84 yueI S Protein of unknown function (DUF1694)
HIFPGDGE_01546 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIFPGDGE_01547 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIFPGDGE_01548 8.1e-213 iscS2 2.8.1.7 E Aminotransferase class V
HIFPGDGE_01549 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIFPGDGE_01550 1.9e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HIFPGDGE_01551 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIFPGDGE_01552 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HIFPGDGE_01553 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
HIFPGDGE_01554 6.2e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HIFPGDGE_01555 1.5e-94 S Protein of unknown function (DUF3990)
HIFPGDGE_01556 2.9e-44
HIFPGDGE_01558 0.0 3.6.3.8 P P-type ATPase
HIFPGDGE_01559 5.6e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
HIFPGDGE_01560 2.5e-52
HIFPGDGE_01561 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIFPGDGE_01562 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HIFPGDGE_01563 5.7e-126 S Haloacid dehalogenase-like hydrolase
HIFPGDGE_01564 2.3e-108 radC L DNA repair protein
HIFPGDGE_01565 2.4e-176 mreB D cell shape determining protein MreB
HIFPGDGE_01566 2e-147 mreC M Involved in formation and maintenance of cell shape
HIFPGDGE_01567 1.3e-93 mreD
HIFPGDGE_01569 6.4e-54 S Protein of unknown function (DUF3397)
HIFPGDGE_01570 6.3e-78 mraZ K Belongs to the MraZ family
HIFPGDGE_01571 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIFPGDGE_01572 1.8e-54 ftsL D Cell division protein FtsL
HIFPGDGE_01573 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HIFPGDGE_01574 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIFPGDGE_01575 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIFPGDGE_01576 5.7e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIFPGDGE_01577 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIFPGDGE_01578 6.7e-243 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIFPGDGE_01579 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIFPGDGE_01580 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIFPGDGE_01581 1.7e-45 yggT S YGGT family
HIFPGDGE_01582 5.7e-149 ylmH S S4 domain protein
HIFPGDGE_01583 2.8e-74 gpsB D DivIVA domain protein
HIFPGDGE_01584 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIFPGDGE_01585 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
HIFPGDGE_01586 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HIFPGDGE_01587 6.7e-37
HIFPGDGE_01588 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIFPGDGE_01589 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
HIFPGDGE_01590 5.4e-56 XK27_04120 S Putative amino acid metabolism
HIFPGDGE_01591 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIFPGDGE_01592 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HIFPGDGE_01593 8.3e-106 S Repeat protein
HIFPGDGE_01594 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIFPGDGE_01595 1.3e-293 L Nuclease-related domain
HIFPGDGE_01596 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HIFPGDGE_01597 2.4e-10 L Psort location Cytoplasmic, score
HIFPGDGE_01598 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIFPGDGE_01599 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HIFPGDGE_01600 4.5e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HIFPGDGE_01601 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HIFPGDGE_01602 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIFPGDGE_01604 5.8e-211 M Glycosyl hydrolases family 25
HIFPGDGE_01605 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
HIFPGDGE_01606 4.1e-67
HIFPGDGE_01607 5.4e-203 xerS L Belongs to the 'phage' integrase family
HIFPGDGE_01608 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIFPGDGE_01609 1e-53 trxA O Belongs to the thioredoxin family
HIFPGDGE_01610 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIFPGDGE_01611 1.1e-50 yrzB S Belongs to the UPF0473 family
HIFPGDGE_01612 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIFPGDGE_01613 2e-42 yrzL S Belongs to the UPF0297 family
HIFPGDGE_01614 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIFPGDGE_01615 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIFPGDGE_01616 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HIFPGDGE_01617 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIFPGDGE_01618 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIFPGDGE_01619 9.6e-41 yajC U Preprotein translocase
HIFPGDGE_01620 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIFPGDGE_01621 5e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIFPGDGE_01622 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIFPGDGE_01623 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIFPGDGE_01624 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIFPGDGE_01625 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIFPGDGE_01626 1.7e-74
HIFPGDGE_01627 2.3e-181 M CHAP domain
HIFPGDGE_01628 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HIFPGDGE_01629 3.7e-295 scrB 3.2.1.26 GH32 G invertase
HIFPGDGE_01630 1.1e-183 scrR K helix_turn _helix lactose operon repressor
HIFPGDGE_01631 2.3e-65 S Alpha beta hydrolase
HIFPGDGE_01632 1.1e-36 S Alpha beta hydrolase
HIFPGDGE_01633 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HIFPGDGE_01634 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HIFPGDGE_01635 7.1e-46
HIFPGDGE_01636 3.1e-148 glcU U sugar transport
HIFPGDGE_01637 0.0 1.3.5.4 C FAD binding domain
HIFPGDGE_01638 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HIFPGDGE_01639 1.7e-249 yhdP S Transporter associated domain
HIFPGDGE_01640 2.3e-119 C nitroreductase
HIFPGDGE_01641 2.1e-39
HIFPGDGE_01642 6.4e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HIFPGDGE_01643 1.6e-80
HIFPGDGE_01644 2.1e-38 glvR K Helix-turn-helix domain, rpiR family
HIFPGDGE_01645 2.3e-83 glvR K Helix-turn-helix domain, rpiR family
HIFPGDGE_01646 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HIFPGDGE_01647 2.5e-71 S hydrolase
HIFPGDGE_01648 8.5e-63 S hydrolase
HIFPGDGE_01649 2.6e-160 rssA S Phospholipase, patatin family
HIFPGDGE_01650 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HIFPGDGE_01651 6.9e-136 glcR K DeoR C terminal sensor domain
HIFPGDGE_01652 2.5e-59 S Enterocin A Immunity
HIFPGDGE_01653 1.2e-154 S hydrolase
HIFPGDGE_01654 3e-133 ydhQ K UbiC transcription regulator-associated domain protein
HIFPGDGE_01655 2.7e-174 rihB 3.2.2.1 F Nucleoside
HIFPGDGE_01656 0.0 kup P Transport of potassium into the cell
HIFPGDGE_01657 3.4e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIFPGDGE_01658 5.4e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIFPGDGE_01659 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
HIFPGDGE_01660 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HIFPGDGE_01661 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HIFPGDGE_01662 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIFPGDGE_01663 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HIFPGDGE_01664 2.6e-103 lacS G Transporter
HIFPGDGE_01665 2.3e-275 1.3.5.4 C FMN_bind
HIFPGDGE_01666 2.7e-226 P Sodium:sulfate symporter transmembrane region
HIFPGDGE_01667 1.3e-109 K LysR family
HIFPGDGE_01668 3.7e-273 1.3.5.4 C FMN_bind
HIFPGDGE_01669 5.2e-111 K LysR family
HIFPGDGE_01670 2.5e-70 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HIFPGDGE_01671 2.5e-16 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HIFPGDGE_01672 5.2e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HIFPGDGE_01673 2.9e-55 dhaM 2.7.1.121 S PTS system fructose IIA component
HIFPGDGE_01674 1.9e-93 dhaL 2.7.1.121 S Dak2
HIFPGDGE_01675 6.4e-174 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HIFPGDGE_01676 0.0 O Belongs to the peptidase S8 family
HIFPGDGE_01677 6.3e-232 malE G Bacterial extracellular solute-binding protein
HIFPGDGE_01678 1.2e-80 lacI3 K helix_turn _helix lactose operon repressor
HIFPGDGE_01679 5.3e-80
HIFPGDGE_01680 6.6e-307 S SLAP domain
HIFPGDGE_01681 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIFPGDGE_01682 1.2e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIFPGDGE_01683 3.1e-130 K Helix-turn-helix domain, rpiR family
HIFPGDGE_01684 1.1e-240 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIFPGDGE_01685 3.3e-169 GK ROK family
HIFPGDGE_01686 4.5e-42
HIFPGDGE_01687 3.9e-267 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIFPGDGE_01688 6.9e-69 S Domain of unknown function (DUF1934)
HIFPGDGE_01689 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIFPGDGE_01690 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIFPGDGE_01691 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIFPGDGE_01692 2.1e-80 K acetyltransferase
HIFPGDGE_01693 1.3e-47 adk 2.7.4.3 F AAA domain
HIFPGDGE_01694 4.4e-285 pipD E Dipeptidase
HIFPGDGE_01695 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HIFPGDGE_01696 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIFPGDGE_01697 1.7e-29 secG U Preprotein translocase
HIFPGDGE_01698 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIFPGDGE_01699 7.3e-148 S Protein of unknown function (DUF805)
HIFPGDGE_01700 3.4e-135 glnQ E ABC transporter, ATP-binding protein
HIFPGDGE_01701 1.3e-290 glnP P ABC transporter permease
HIFPGDGE_01702 8.9e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HIFPGDGE_01703 5.8e-64 yeaO S Protein of unknown function, DUF488
HIFPGDGE_01704 1.3e-124 terC P Integral membrane protein TerC family
HIFPGDGE_01705 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HIFPGDGE_01706 8.5e-133 cobB K SIR2 family
HIFPGDGE_01707 1.5e-274 S Archaea bacterial proteins of unknown function
HIFPGDGE_01709 3.6e-90 ntd 2.4.2.6 F Nucleoside
HIFPGDGE_01710 3.9e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HIFPGDGE_01711 3.4e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HIFPGDGE_01712 5.2e-84 uspA T universal stress protein
HIFPGDGE_01713 1.2e-150 phnD P Phosphonate ABC transporter
HIFPGDGE_01714 7e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HIFPGDGE_01715 1.2e-111 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HIFPGDGE_01716 2.2e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HIFPGDGE_01717 3.3e-106 tag 3.2.2.20 L glycosylase
HIFPGDGE_01718 3.9e-84
HIFPGDGE_01719 1.6e-271 S Calcineurin-like phosphoesterase
HIFPGDGE_01720 0.0 asnB 6.3.5.4 E Asparagine synthase
HIFPGDGE_01721 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HIFPGDGE_01722 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HIFPGDGE_01723 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIFPGDGE_01724 6.2e-103 S Iron-sulfur cluster assembly protein
HIFPGDGE_01725 1.5e-230 XK27_04775 S PAS domain
HIFPGDGE_01726 4.7e-211 yttB EGP Major facilitator Superfamily
HIFPGDGE_01727 0.0 pepO 3.4.24.71 O Peptidase family M13
HIFPGDGE_01728 0.0 kup P Transport of potassium into the cell
HIFPGDGE_01729 7.3e-74
HIFPGDGE_01730 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIFPGDGE_01731 8.7e-229 S Tetratricopeptide repeat protein
HIFPGDGE_01732 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIFPGDGE_01733 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HIFPGDGE_01734 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
HIFPGDGE_01735 5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HIFPGDGE_01736 2.7e-18 M Lysin motif
HIFPGDGE_01737 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIFPGDGE_01738 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIFPGDGE_01739 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIFPGDGE_01740 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIFPGDGE_01741 6.7e-30 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIFPGDGE_01742 2.9e-165 xerD D recombinase XerD
HIFPGDGE_01743 2.3e-167 cvfB S S1 domain
HIFPGDGE_01744 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HIFPGDGE_01745 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HIFPGDGE_01746 4.3e-75
HIFPGDGE_01747 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIFPGDGE_01748 1.3e-168 dnaI L Primosomal protein DnaI
HIFPGDGE_01749 3.3e-250 dnaB L Replication initiation and membrane attachment
HIFPGDGE_01750 3.9e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIFPGDGE_01751 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIFPGDGE_01752 2.7e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIFPGDGE_01753 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIFPGDGE_01754 3.8e-30
HIFPGDGE_01755 2.4e-92 V ABC transporter, ATP-binding protein
HIFPGDGE_01756 4.7e-60 S ABC-2 family transporter protein
HIFPGDGE_01757 2.1e-76 S ABC-2 family transporter protein
HIFPGDGE_01758 8.2e-230 pbuG S permease
HIFPGDGE_01759 3.7e-140 cof S haloacid dehalogenase-like hydrolase
HIFPGDGE_01760 9.4e-72
HIFPGDGE_01761 1.6e-123 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HIFPGDGE_01762 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HIFPGDGE_01763 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIFPGDGE_01764 3.7e-159 yeaE S Aldo/keto reductase family
HIFPGDGE_01765 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
HIFPGDGE_01766 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
HIFPGDGE_01767 1.3e-282 xylG 3.6.3.17 S ABC transporter
HIFPGDGE_01768 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
HIFPGDGE_01769 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
HIFPGDGE_01771 1.2e-40
HIFPGDGE_01772 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
HIFPGDGE_01773 1.1e-07
HIFPGDGE_01775 1.7e-16
HIFPGDGE_01776 2e-30
HIFPGDGE_01777 2.6e-168 M Glycosyl hydrolases family 25
HIFPGDGE_01779 3.8e-84 dps P Belongs to the Dps family
HIFPGDGE_01780 3.3e-54 S pyridoxamine 5-phosphate
HIFPGDGE_01781 2e-129 yobV1 K WYL domain
HIFPGDGE_01782 1.9e-86 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HIFPGDGE_01783 2.1e-57 dps P Belongs to the Dps family
HIFPGDGE_01784 3.2e-19
HIFPGDGE_01786 3.2e-182 M Glycosyl hydrolases family 25
HIFPGDGE_01787 6.1e-27
HIFPGDGE_01788 7e-16
HIFPGDGE_01790 1.7e-16
HIFPGDGE_01792 1.2e-10
HIFPGDGE_01793 7.7e-10 C Flavodoxin
HIFPGDGE_01794 3.2e-79 S X-Pro dipeptidyl-peptidase (S15 family)
HIFPGDGE_01795 3.3e-45 K Tetracycline repressor, C-terminal all-alpha domain
HIFPGDGE_01797 6.6e-90 K LysR substrate binding domain
HIFPGDGE_01798 8.9e-34 S Domain of unknown function (DUF4440)
HIFPGDGE_01799 9.8e-69 GM NAD(P)H-binding
HIFPGDGE_01800 7e-135 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HIFPGDGE_01801 7.9e-49 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIFPGDGE_01802 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HIFPGDGE_01803 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HIFPGDGE_01804 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HIFPGDGE_01805 9.7e-52 S Iron-sulfur cluster assembly protein
HIFPGDGE_01806 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HIFPGDGE_01807 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HIFPGDGE_01808 2.4e-44
HIFPGDGE_01809 2.1e-285 lsa S ABC transporter
HIFPGDGE_01810 1.2e-86 lacI3 K helix_turn _helix lactose operon repressor
HIFPGDGE_01811 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HIFPGDGE_01812 1.5e-258 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HIFPGDGE_01813 1.4e-62
HIFPGDGE_01814 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HIFPGDGE_01815 2.9e-201 L COG2826 Transposase and inactivated derivatives, IS30 family
HIFPGDGE_01816 1.3e-252 E Amino acid permease
HIFPGDGE_01817 1.7e-99 L An automated process has identified a potential problem with this gene model
HIFPGDGE_01819 1.9e-263 E ABC transporter, substratebinding protein
HIFPGDGE_01821 1.6e-160 S interspecies interaction between organisms
HIFPGDGE_01822 1.1e-212 tnpB L Putative transposase DNA-binding domain
HIFPGDGE_01823 8.9e-33
HIFPGDGE_01825 3.1e-32 S protein encoded in hypervariable junctions of pilus gene clusters
HIFPGDGE_01826 2.4e-13 hicA S HicA toxin of bacterial toxin-antitoxin,
HIFPGDGE_01828 1.7e-147
HIFPGDGE_01829 1.5e-169
HIFPGDGE_01830 2e-263 glnA 6.3.1.2 E glutamine synthetase
HIFPGDGE_01831 2.9e-224 ynbB 4.4.1.1 P aluminum resistance
HIFPGDGE_01832 1.1e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIFPGDGE_01833 1.5e-65 yqhL P Rhodanese-like protein
HIFPGDGE_01834 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HIFPGDGE_01835 3.1e-119 gluP 3.4.21.105 S Rhomboid family
HIFPGDGE_01836 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIFPGDGE_01837 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HIFPGDGE_01838 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HIFPGDGE_01839 0.0 S membrane
HIFPGDGE_01840 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HIFPGDGE_01841 1.3e-38 S RelB antitoxin
HIFPGDGE_01842 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HIFPGDGE_01843 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIFPGDGE_01844 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
HIFPGDGE_01845 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIFPGDGE_01846 8.7e-159 isdE P Periplasmic binding protein
HIFPGDGE_01847 6.3e-123 M Iron Transport-associated domain
HIFPGDGE_01848 3e-09 isdH M Iron Transport-associated domain
HIFPGDGE_01849 8.4e-89
HIFPGDGE_01850 6.4e-113 S SLAP domain
HIFPGDGE_01851 1.2e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIFPGDGE_01852 3.1e-71 2.5.1.74 H UbiA prenyltransferase family
HIFPGDGE_01853 7.7e-26
HIFPGDGE_01854 5.7e-84 S PFAM Archaeal ATPase
HIFPGDGE_01855 2.2e-85 S PFAM Archaeal ATPase
HIFPGDGE_01856 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIFPGDGE_01858 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIFPGDGE_01859 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
HIFPGDGE_01860 1.3e-61 M Glycosyl hydrolases family 25
HIFPGDGE_01861 2.6e-61 M Glycosyl hydrolases family 25
HIFPGDGE_01865 8e-37 V HNH nucleases
HIFPGDGE_01867 1.7e-25 L Phage terminase, small subunit
HIFPGDGE_01868 3.9e-180 S overlaps another CDS with the same product name
HIFPGDGE_01870 1.4e-92 S Phage portal protein
HIFPGDGE_01871 1.6e-46 S Clp protease
HIFPGDGE_01872 1.9e-82 S Phage capsid family
HIFPGDGE_01873 7.9e-14 S Phage gp6-like head-tail connector protein
HIFPGDGE_01875 1.3e-29 S Bacteriophage HK97-gp10, putative tail-component
HIFPGDGE_01876 8.9e-13 S Protein of unknown function (DUF806)
HIFPGDGE_01877 3.5e-28 S Phage tail tube protein
HIFPGDGE_01880 1.1e-141 D NLP P60 protein
HIFPGDGE_01881 1.2e-31 S phage tail
HIFPGDGE_01882 2.1e-246 S Phage minor structural protein
HIFPGDGE_01884 7.1e-13 S Domain of unknown function (DUF2479)
HIFPGDGE_01886 1.4e-17 GT2,GT4 LM gp58-like protein
HIFPGDGE_01892 4e-22 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HIFPGDGE_01893 2.6e-102 M hydrolase, family 25
HIFPGDGE_01894 9.6e-158 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIFPGDGE_01895 1.6e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIFPGDGE_01896 1.2e-107 hlyIII S protein, hemolysin III
HIFPGDGE_01897 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
HIFPGDGE_01898 7.1e-36 yozE S Belongs to the UPF0346 family
HIFPGDGE_01899 1.1e-66 yjcE P NhaP-type Na H and K H
HIFPGDGE_01900 1.5e-40 yjcE P Sodium proton antiporter
HIFPGDGE_01901 1.9e-94 yjcE P Sodium proton antiporter
HIFPGDGE_01902 8.1e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIFPGDGE_01903 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIFPGDGE_01904 5.8e-152 dprA LU DNA protecting protein DprA
HIFPGDGE_01905 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIFPGDGE_01906 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HIFPGDGE_01907 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
HIFPGDGE_01908 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HIFPGDGE_01909 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HIFPGDGE_01910 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
HIFPGDGE_01911 8.3e-87 C Aldo keto reductase
HIFPGDGE_01912 7.1e-63 M LysM domain protein
HIFPGDGE_01913 4.1e-101 xerD L Phage integrase, N-terminal SAM-like domain
HIFPGDGE_01914 1.9e-109 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HIFPGDGE_01915 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component
HIFPGDGE_01916 3.8e-103 potB E Binding-protein-dependent transport system inner membrane component
HIFPGDGE_01917 4e-98 rihB 3.2.2.1 F Nucleoside
HIFPGDGE_01918 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIFPGDGE_01919 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HIFPGDGE_01920 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIFPGDGE_01921 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HIFPGDGE_01922 9.2e-201 tnpB L Putative transposase DNA-binding domain
HIFPGDGE_01923 4.2e-84 yqeG S HAD phosphatase, family IIIA
HIFPGDGE_01924 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
HIFPGDGE_01925 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIFPGDGE_01926 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HIFPGDGE_01927 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIFPGDGE_01928 4.6e-216 ylbM S Belongs to the UPF0348 family
HIFPGDGE_01929 4.7e-97 yceD S Uncharacterized ACR, COG1399
HIFPGDGE_01930 1.2e-126 K response regulator
HIFPGDGE_01931 1.3e-277 arlS 2.7.13.3 T Histidine kinase
HIFPGDGE_01932 1e-12
HIFPGDGE_01933 1.5e-97 S CAAX protease self-immunity
HIFPGDGE_01934 6.1e-224 S SLAP domain
HIFPGDGE_01935 5.7e-83 S Aminoacyl-tRNA editing domain
HIFPGDGE_01936 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIFPGDGE_01937 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HIFPGDGE_01938 7.7e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIFPGDGE_01939 4.5e-58 yodB K Transcriptional regulator, HxlR family
HIFPGDGE_01941 8.3e-24 papP P ABC transporter, permease protein
HIFPGDGE_01942 3.3e-119
HIFPGDGE_01943 4.2e-101
HIFPGDGE_01944 6e-210 pepA E M42 glutamyl aminopeptidase
HIFPGDGE_01945 2.2e-311 ybiT S ABC transporter, ATP-binding protein
HIFPGDGE_01946 5.9e-174 S Aldo keto reductase
HIFPGDGE_01947 2.5e-138
HIFPGDGE_01948 3.3e-203 steT E amino acid
HIFPGDGE_01949 6.8e-240 steT E amino acid
HIFPGDGE_01950 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HIFPGDGE_01951 6.4e-148 glnH ET ABC transporter
HIFPGDGE_01952 1.4e-80 K Transcriptional regulator, MarR family
HIFPGDGE_01953 1.7e-310 XK27_09600 V ABC transporter, ATP-binding protein
HIFPGDGE_01954 0.0 V ABC transporter transmembrane region
HIFPGDGE_01955 3.8e-102 S ABC-type cobalt transport system, permease component
HIFPGDGE_01956 8.3e-202 G MFS/sugar transport protein
HIFPGDGE_01957 1.8e-41 G MFS/sugar transport protein
HIFPGDGE_01958 1.8e-113 udk 2.7.1.48 F Zeta toxin
HIFPGDGE_01959 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIFPGDGE_01960 1.5e-149 glnH ET ABC transporter substrate-binding protein
HIFPGDGE_01961 9.7e-91 gluC P ABC transporter permease
HIFPGDGE_01962 4.7e-109 glnP P ABC transporter permease
HIFPGDGE_01963 1.1e-164 S Protein of unknown function (DUF2974)
HIFPGDGE_01964 5.6e-86
HIFPGDGE_01965 5.4e-211 S Uncharacterized protein conserved in bacteria (DUF2325)
HIFPGDGE_01966 4.2e-264 S Fibronectin type III domain
HIFPGDGE_01967 1.6e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIFPGDGE_01968 9e-54
HIFPGDGE_01970 4.6e-257 pepC 3.4.22.40 E aminopeptidase
HIFPGDGE_01971 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIFPGDGE_01972 1.7e-301 oppA E ABC transporter, substratebinding protein
HIFPGDGE_01973 1.6e-310 oppA E ABC transporter, substratebinding protein
HIFPGDGE_01974 4.3e-217 mdtG EGP Major facilitator Superfamily
HIFPGDGE_01975 7.8e-261 emrY EGP Major facilitator Superfamily
HIFPGDGE_01976 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIFPGDGE_01977 2.9e-238 pyrP F Permease
HIFPGDGE_01978 9.3e-278 K Putative DNA-binding domain
HIFPGDGE_01979 7.1e-98 G Aldose 1-epimerase
HIFPGDGE_01980 2.1e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIFPGDGE_01981 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIFPGDGE_01982 0.0 XK27_08315 M Sulfatase
HIFPGDGE_01983 7.5e-103 G Phosphoglycerate mutase family
HIFPGDGE_01984 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HIFPGDGE_01986 3.7e-174 L Bifunctional protein
HIFPGDGE_01987 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HIFPGDGE_01988 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
HIFPGDGE_01989 5.6e-179 S PFAM Archaeal ATPase
HIFPGDGE_01990 2.4e-73 S cog cog1373

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)