ORF_ID e_value Gene_name EC_number CAZy COGs Description
FFNDPMCA_00002 2.7e-17
FFNDPMCA_00004 6.4e-260 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
FFNDPMCA_00005 4.7e-38 M CHAP domain
FFNDPMCA_00010 8.2e-12
FFNDPMCA_00011 8.5e-16 S SLAP domain
FFNDPMCA_00012 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
FFNDPMCA_00013 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FFNDPMCA_00014 1e-107 ypsA S Belongs to the UPF0398 family
FFNDPMCA_00015 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FFNDPMCA_00016 3.1e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
FFNDPMCA_00017 4e-242 cpdA S Calcineurin-like phosphoesterase
FFNDPMCA_00018 7.6e-79
FFNDPMCA_00019 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
FFNDPMCA_00020 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FFNDPMCA_00021 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FFNDPMCA_00022 7.2e-56 yheA S Belongs to the UPF0342 family
FFNDPMCA_00023 1.2e-230 yhaO L Ser Thr phosphatase family protein
FFNDPMCA_00024 0.0 L AAA domain
FFNDPMCA_00025 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
FFNDPMCA_00026 2.9e-23
FFNDPMCA_00027 2.4e-51 S Domain of unknown function DUF1829
FFNDPMCA_00028 1.1e-265
FFNDPMCA_00029 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
FFNDPMCA_00030 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FFNDPMCA_00031 3.9e-25
FFNDPMCA_00032 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
FFNDPMCA_00033 5.7e-135 ecsA V ABC transporter, ATP-binding protein
FFNDPMCA_00034 2.9e-221 ecsB U ABC transporter
FFNDPMCA_00035 5.6e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FFNDPMCA_00036 2.3e-29 S Protein of unknown function (DUF805)
FFNDPMCA_00037 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FFNDPMCA_00038 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FFNDPMCA_00039 2.9e-174
FFNDPMCA_00040 1e-248 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
FFNDPMCA_00041 2.5e-234 mepA V MATE efflux family protein
FFNDPMCA_00042 1.5e-172 S SLAP domain
FFNDPMCA_00043 2.5e-74 L Putative transposase DNA-binding domain
FFNDPMCA_00044 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FFNDPMCA_00045 1.7e-29 secG U Preprotein translocase
FFNDPMCA_00046 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FFNDPMCA_00047 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
FFNDPMCA_00048 2.3e-275 1.3.5.4 C FMN_bind
FFNDPMCA_00049 2.7e-226 P Sodium:sulfate symporter transmembrane region
FFNDPMCA_00050 1.3e-109 K LysR family
FFNDPMCA_00051 3.7e-273 1.3.5.4 C FMN_bind
FFNDPMCA_00052 5.2e-111 K LysR family
FFNDPMCA_00053 2.5e-70 3.6.4.12 S PD-(D/E)XK nuclease family transposase
FFNDPMCA_00054 2.5e-16 3.6.4.12 S PD-(D/E)XK nuclease family transposase
FFNDPMCA_00055 5.2e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
FFNDPMCA_00056 2.9e-55 dhaM 2.7.1.121 S PTS system fructose IIA component
FFNDPMCA_00057 1.9e-93 dhaL 2.7.1.121 S Dak2
FFNDPMCA_00058 6.4e-174 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
FFNDPMCA_00059 0.0 O Belongs to the peptidase S8 family
FFNDPMCA_00060 6.3e-232 malE G Bacterial extracellular solute-binding protein
FFNDPMCA_00061 1.2e-80 lacI3 K helix_turn _helix lactose operon repressor
FFNDPMCA_00062 1.9e-75 M LysM domain
FFNDPMCA_00063 1.3e-42
FFNDPMCA_00065 3.5e-29
FFNDPMCA_00066 4.5e-76 yniG EGP Major facilitator Superfamily
FFNDPMCA_00067 5.4e-237 L transposase, IS605 OrfB family
FFNDPMCA_00068 1.4e-109 yniG EGP Major facilitator Superfamily
FFNDPMCA_00069 2.4e-128 S cog cog1373
FFNDPMCA_00070 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
FFNDPMCA_00071 0.0 oppA E ABC transporter
FFNDPMCA_00072 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
FFNDPMCA_00073 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
FFNDPMCA_00074 1e-137 S Protein of unknown function (DUF3100)
FFNDPMCA_00075 9.7e-83 S An automated process has identified a potential problem with this gene model
FFNDPMCA_00076 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
FFNDPMCA_00078 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FFNDPMCA_00079 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
FFNDPMCA_00080 1.3e-61 M Glycosyl hydrolases family 25
FFNDPMCA_00081 2.6e-61 M Glycosyl hydrolases family 25
FFNDPMCA_00082 7.9e-49 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FFNDPMCA_00083 7e-135 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
FFNDPMCA_00084 9.8e-69 GM NAD(P)H-binding
FFNDPMCA_00085 8.9e-34 S Domain of unknown function (DUF4440)
FFNDPMCA_00086 6.6e-90 K LysR substrate binding domain
FFNDPMCA_00088 3.3e-45 K Tetracycline repressor, C-terminal all-alpha domain
FFNDPMCA_00089 3.2e-79 S X-Pro dipeptidyl-peptidase (S15 family)
FFNDPMCA_00090 7.7e-10 C Flavodoxin
FFNDPMCA_00091 7.9e-210 S Bacterial protein of unknown function (DUF871)
FFNDPMCA_00092 2.3e-43 ybhL S Belongs to the BI1 family
FFNDPMCA_00093 1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FFNDPMCA_00094 4.8e-34 S reductase
FFNDPMCA_00095 4.4e-39 S reductase
FFNDPMCA_00096 2.7e-32 S reductase
FFNDPMCA_00097 1.3e-148 yxeH S hydrolase
FFNDPMCA_00098 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFNDPMCA_00099 1.1e-243 yfnA E Amino Acid
FFNDPMCA_00100 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
FFNDPMCA_00101 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FFNDPMCA_00102 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFNDPMCA_00103 2.2e-292 I Acyltransferase
FFNDPMCA_00104 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FFNDPMCA_00105 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FFNDPMCA_00106 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
FFNDPMCA_00107 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
FFNDPMCA_00108 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
FFNDPMCA_00109 2.3e-23 S Protein of unknown function (DUF2929)
FFNDPMCA_00110 0.0 dnaE 2.7.7.7 L DNA polymerase
FFNDPMCA_00111 0.0 clpE O Belongs to the ClpA ClpB family
FFNDPMCA_00112 5.3e-26
FFNDPMCA_00113 8.5e-41 ptsH G phosphocarrier protein HPR
FFNDPMCA_00114 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFNDPMCA_00115 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FFNDPMCA_00116 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FFNDPMCA_00117 2.9e-159 coiA 3.6.4.12 S Competence protein
FFNDPMCA_00118 4.6e-114 yjbH Q Thioredoxin
FFNDPMCA_00119 5.2e-110 yjbK S CYTH
FFNDPMCA_00120 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
FFNDPMCA_00121 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FFNDPMCA_00122 5.6e-115 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FFNDPMCA_00123 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
FFNDPMCA_00124 4.2e-92 S SNARE associated Golgi protein
FFNDPMCA_00125 1.9e-37
FFNDPMCA_00126 7e-50
FFNDPMCA_00127 8.7e-53 S haloacid dehalogenase-like hydrolase
FFNDPMCA_00128 7.4e-86 S haloacid dehalogenase-like hydrolase
FFNDPMCA_00129 8.5e-290 V ABC-type multidrug transport system, ATPase and permease components
FFNDPMCA_00130 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
FFNDPMCA_00131 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
FFNDPMCA_00132 8.5e-178 I Carboxylesterase family
FFNDPMCA_00134 1e-205 M Glycosyl hydrolases family 25
FFNDPMCA_00135 2.8e-157 cinI S Serine hydrolase (FSH1)
FFNDPMCA_00136 4.3e-298 S Predicted membrane protein (DUF2207)
FFNDPMCA_00137 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
FFNDPMCA_00139 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
FFNDPMCA_00140 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFNDPMCA_00141 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
FFNDPMCA_00142 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
FFNDPMCA_00143 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FFNDPMCA_00144 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FFNDPMCA_00145 3.4e-71 yqhY S Asp23 family, cell envelope-related function
FFNDPMCA_00146 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFNDPMCA_00147 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFNDPMCA_00148 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FFNDPMCA_00149 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FFNDPMCA_00150 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FFNDPMCA_00151 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
FFNDPMCA_00152 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
FFNDPMCA_00153 1.1e-77 6.3.3.2 S ASCH
FFNDPMCA_00154 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
FFNDPMCA_00155 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FFNDPMCA_00156 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FFNDPMCA_00157 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFNDPMCA_00158 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FFNDPMCA_00159 1.1e-138 stp 3.1.3.16 T phosphatase
FFNDPMCA_00160 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
FFNDPMCA_00161 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FFNDPMCA_00162 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
FFNDPMCA_00163 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
FFNDPMCA_00164 1.4e-30
FFNDPMCA_00165 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
FFNDPMCA_00166 4e-57 asp S Asp23 family, cell envelope-related function
FFNDPMCA_00167 7.6e-305 yloV S DAK2 domain fusion protein YloV
FFNDPMCA_00168 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FFNDPMCA_00169 8.3e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FFNDPMCA_00170 9.8e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFNDPMCA_00171 3.4e-100 2.7.6.5 T Region found in RelA / SpoT proteins
FFNDPMCA_00172 3.2e-105 K response regulator
FFNDPMCA_00173 1.1e-103 sptS 2.7.13.3 T Histidine kinase
FFNDPMCA_00174 2.6e-103 sptS 2.7.13.3 T Histidine kinase
FFNDPMCA_00175 7.2e-209 EGP Major facilitator Superfamily
FFNDPMCA_00176 2.3e-69 O OsmC-like protein
FFNDPMCA_00177 2.2e-85 S Protein of unknown function (DUF805)
FFNDPMCA_00178 2.2e-78
FFNDPMCA_00179 3.1e-93
FFNDPMCA_00180 9.9e-180
FFNDPMCA_00181 5.8e-83 S Fic/DOC family
FFNDPMCA_00182 3.3e-275 yjeM E Amino Acid
FFNDPMCA_00183 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFNDPMCA_00184 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
FFNDPMCA_00185 5.9e-300 L Transposase
FFNDPMCA_00186 4.5e-144 ybbH_2 K rpiR family
FFNDPMCA_00187 3.1e-187 S Bacterial protein of unknown function (DUF871)
FFNDPMCA_00188 1.4e-183 yfeW 3.4.16.4 V Beta-lactamase
FFNDPMCA_00189 1.3e-141 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FFNDPMCA_00190 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
FFNDPMCA_00191 1.5e-259 qacA EGP Major facilitator Superfamily
FFNDPMCA_00192 1.6e-219 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FFNDPMCA_00195 5.7e-166 psaA P Belongs to the bacterial solute-binding protein 9 family
FFNDPMCA_00197 1.2e-89 S N-methyltransferase activity
FFNDPMCA_00198 2.4e-169 S Domain of unknown function (DUF3440)
FFNDPMCA_00199 1.9e-156 S Type III restriction enzyme, res subunit
FFNDPMCA_00202 2.1e-14
FFNDPMCA_00203 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
FFNDPMCA_00209 3.5e-50 dnaC L IstB-like ATP binding protein
FFNDPMCA_00210 2.7e-34 S Conserved phage C-terminus (Phg_2220_C)
FFNDPMCA_00211 6.5e-57 S Protein of unknown function (DUF1071)
FFNDPMCA_00216 1.8e-07 K Helix-turn-helix XRE-family like proteins
FFNDPMCA_00217 7.2e-10
FFNDPMCA_00221 4.3e-98 S AntA/AntB antirepressor
FFNDPMCA_00222 2.9e-12
FFNDPMCA_00227 1.3e-81 S DNA binding
FFNDPMCA_00228 9.5e-12 K Helix-turn-helix XRE-family like proteins
FFNDPMCA_00229 6.5e-23 K Cro/C1-type HTH DNA-binding domain
FFNDPMCA_00230 3.3e-18 S Pfam:Peptidase_M78
FFNDPMCA_00235 1.6e-20 S YjcQ protein
FFNDPMCA_00236 4.2e-180 sip L Belongs to the 'phage' integrase family
FFNDPMCA_00237 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FFNDPMCA_00238 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FFNDPMCA_00239 0.0 dnaK O Heat shock 70 kDa protein
FFNDPMCA_00240 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FFNDPMCA_00241 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FFNDPMCA_00242 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
FFNDPMCA_00243 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FFNDPMCA_00244 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FFNDPMCA_00245 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FFNDPMCA_00246 3.2e-47 rplGA J ribosomal protein
FFNDPMCA_00247 8.8e-47 ylxR K Protein of unknown function (DUF448)
FFNDPMCA_00248 1.4e-196 nusA K Participates in both transcription termination and antitermination
FFNDPMCA_00249 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
FFNDPMCA_00250 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FFNDPMCA_00251 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FFNDPMCA_00252 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
FFNDPMCA_00253 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
FFNDPMCA_00254 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FFNDPMCA_00255 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FFNDPMCA_00256 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
FFNDPMCA_00257 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FFNDPMCA_00258 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
FFNDPMCA_00259 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
FFNDPMCA_00260 2.9e-116 plsC 2.3.1.51 I Acyltransferase
FFNDPMCA_00261 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
FFNDPMCA_00262 0.0 pepO 3.4.24.71 O Peptidase family M13
FFNDPMCA_00263 0.0 mdlB V ABC transporter
FFNDPMCA_00264 0.0 mdlA V ABC transporter
FFNDPMCA_00265 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
FFNDPMCA_00266 3e-38 ynzC S UPF0291 protein
FFNDPMCA_00267 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FFNDPMCA_00268 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
FFNDPMCA_00269 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
FFNDPMCA_00270 4.6e-213 S SLAP domain
FFNDPMCA_00271 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FFNDPMCA_00272 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
FFNDPMCA_00273 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FFNDPMCA_00274 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
FFNDPMCA_00275 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FFNDPMCA_00276 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FFNDPMCA_00277 2.7e-258 yfnA E amino acid
FFNDPMCA_00278 0.0 V FtsX-like permease family
FFNDPMCA_00279 4.1e-133 cysA V ABC transporter, ATP-binding protein
FFNDPMCA_00280 3.4e-23
FFNDPMCA_00282 2.5e-288 pipD E Dipeptidase
FFNDPMCA_00283 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FFNDPMCA_00284 0.0 smc D Required for chromosome condensation and partitioning
FFNDPMCA_00285 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FFNDPMCA_00286 2.1e-308 oppA E ABC transporter substrate-binding protein
FFNDPMCA_00287 1.2e-300 oppA E ABC transporter substrate-binding protein
FFNDPMCA_00288 1.2e-134 oppC P Binding-protein-dependent transport system inner membrane component
FFNDPMCA_00289 5.7e-172 oppB P ABC transporter permease
FFNDPMCA_00290 1.5e-170 oppF P Belongs to the ABC transporter superfamily
FFNDPMCA_00291 1.1e-192 oppD P Belongs to the ABC transporter superfamily
FFNDPMCA_00292 4.1e-101 xerD L Phage integrase, N-terminal SAM-like domain
FFNDPMCA_00293 7.1e-63 M LysM domain protein
FFNDPMCA_00294 8.3e-87 C Aldo keto reductase
FFNDPMCA_00295 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
FFNDPMCA_00296 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FFNDPMCA_00297 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FFNDPMCA_00298 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
FFNDPMCA_00299 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FFNDPMCA_00300 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFNDPMCA_00301 5.8e-152 dprA LU DNA protecting protein DprA
FFNDPMCA_00302 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FFNDPMCA_00303 8.1e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FFNDPMCA_00304 1.9e-94 yjcE P Sodium proton antiporter
FFNDPMCA_00305 1.5e-40 yjcE P Sodium proton antiporter
FFNDPMCA_00306 1.1e-66 yjcE P NhaP-type Na H and K H
FFNDPMCA_00307 7.1e-36 yozE S Belongs to the UPF0346 family
FFNDPMCA_00308 2e-144 DegV S Uncharacterised protein, DegV family COG1307
FFNDPMCA_00309 1.2e-107 hlyIII S protein, hemolysin III
FFNDPMCA_00310 1.6e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FFNDPMCA_00311 9.6e-158 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFNDPMCA_00312 2.6e-102 M hydrolase, family 25
FFNDPMCA_00313 4e-22 S Bacteriophage holin of superfamily 6 (Holin_LLH)
FFNDPMCA_00319 1.4e-17 GT2,GT4 LM gp58-like protein
FFNDPMCA_00321 7.1e-13 S Domain of unknown function (DUF2479)
FFNDPMCA_00323 2.1e-246 S Phage minor structural protein
FFNDPMCA_00324 1.2e-31 S phage tail
FFNDPMCA_00325 1.1e-141 D NLP P60 protein
FFNDPMCA_00328 3.5e-28 S Phage tail tube protein
FFNDPMCA_00329 8.9e-13 S Protein of unknown function (DUF806)
FFNDPMCA_00330 1.3e-29 S Bacteriophage HK97-gp10, putative tail-component
FFNDPMCA_00332 7.9e-14 S Phage gp6-like head-tail connector protein
FFNDPMCA_00333 1.9e-82 S Phage capsid family
FFNDPMCA_00334 1.6e-46 S Clp protease
FFNDPMCA_00335 1.4e-92 S Phage portal protein
FFNDPMCA_00337 3.9e-180 S overlaps another CDS with the same product name
FFNDPMCA_00338 1.7e-25 L Phage terminase, small subunit
FFNDPMCA_00340 8e-37 V HNH nucleases
FFNDPMCA_00344 2.2e-250 lctP C L-lactate permease
FFNDPMCA_00345 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
FFNDPMCA_00346 1.6e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FFNDPMCA_00347 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FFNDPMCA_00348 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FFNDPMCA_00349 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FFNDPMCA_00350 2.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FFNDPMCA_00351 7.8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FFNDPMCA_00352 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FFNDPMCA_00353 3.2e-178 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
FFNDPMCA_00354 4.6e-100 3.6.1.27 I Acid phosphatase homologues
FFNDPMCA_00355 2.8e-151 yitS S Uncharacterised protein, DegV family COG1307
FFNDPMCA_00356 4.4e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FFNDPMCA_00357 7.5e-91 S Domain of unknown function (DUF4767)
FFNDPMCA_00358 2.2e-142 S Belongs to the UPF0246 family
FFNDPMCA_00359 6e-140 aroD S Alpha/beta hydrolase family
FFNDPMCA_00360 3.5e-111 G phosphoglycerate mutase
FFNDPMCA_00361 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
FFNDPMCA_00362 3.3e-176 hrtB V ABC transporter permease
FFNDPMCA_00363 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
FFNDPMCA_00364 1.3e-273 pipD E Dipeptidase
FFNDPMCA_00365 3.2e-11
FFNDPMCA_00366 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
FFNDPMCA_00367 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
FFNDPMCA_00368 3.7e-128 K UTRA domain
FFNDPMCA_00369 5.8e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FFNDPMCA_00370 6.4e-90 alkD L DNA alkylation repair enzyme
FFNDPMCA_00371 5.4e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
FFNDPMCA_00372 3.9e-82
FFNDPMCA_00373 3.6e-39 C FMN_bind
FFNDPMCA_00374 4.6e-299 I Protein of unknown function (DUF2974)
FFNDPMCA_00375 2.9e-159 pbpX1 V Beta-lactamase
FFNDPMCA_00376 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FFNDPMCA_00377 3.2e-217 aspC 2.6.1.1 E Aminotransferase
FFNDPMCA_00378 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FFNDPMCA_00379 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFNDPMCA_00380 5.2e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FFNDPMCA_00381 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FFNDPMCA_00382 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FFNDPMCA_00383 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
FFNDPMCA_00384 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FFNDPMCA_00385 3.4e-175 yjeM E Amino Acid
FFNDPMCA_00386 7.8e-39 yjeM E Amino Acid
FFNDPMCA_00387 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
FFNDPMCA_00388 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FFNDPMCA_00389 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FFNDPMCA_00390 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFNDPMCA_00391 1.3e-148
FFNDPMCA_00392 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FFNDPMCA_00393 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FFNDPMCA_00394 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
FFNDPMCA_00395 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
FFNDPMCA_00396 0.0 comEC S Competence protein ComEC
FFNDPMCA_00397 3.1e-79 comEA L Competence protein ComEA
FFNDPMCA_00398 2.4e-187 ylbL T Belongs to the peptidase S16 family
FFNDPMCA_00399 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FFNDPMCA_00400 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
FFNDPMCA_00401 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
FFNDPMCA_00402 5.9e-211 ftsW D Belongs to the SEDS family
FFNDPMCA_00403 0.0 typA T GTP-binding protein TypA
FFNDPMCA_00404 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FFNDPMCA_00405 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FFNDPMCA_00406 5.4e-203 xerS L Belongs to the 'phage' integrase family
FFNDPMCA_00407 4.1e-67
FFNDPMCA_00408 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
FFNDPMCA_00409 5.8e-211 M Glycosyl hydrolases family 25
FFNDPMCA_00411 1.4e-38
FFNDPMCA_00412 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
FFNDPMCA_00413 1.4e-07
FFNDPMCA_00415 7.5e-17
FFNDPMCA_00416 2.9e-29
FFNDPMCA_00417 8.8e-172 M Glycosyl hydrolases family 25
FFNDPMCA_00418 5.9e-24
FFNDPMCA_00419 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
FFNDPMCA_00420 1.5e-102 srtA 3.4.22.70 M sortase family
FFNDPMCA_00421 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
FFNDPMCA_00422 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFNDPMCA_00423 2.7e-58 P ABC transporter
FFNDPMCA_00424 2.4e-284 V ABC-type multidrug transport system, ATPase and permease components
FFNDPMCA_00425 1.2e-247 yifK E Amino acid permease
FFNDPMCA_00426 9.1e-178 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FFNDPMCA_00427 2.2e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FFNDPMCA_00428 0.0 aha1 P E1-E2 ATPase
FFNDPMCA_00429 1.9e-175 F DNA/RNA non-specific endonuclease
FFNDPMCA_00430 2e-160 metQ2 P Belongs to the nlpA lipoprotein family
FFNDPMCA_00431 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFNDPMCA_00432 2e-73 metI P ABC transporter permease
FFNDPMCA_00433 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FFNDPMCA_00434 1.9e-261 frdC 1.3.5.4 C FAD binding domain
FFNDPMCA_00435 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FFNDPMCA_00436 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
FFNDPMCA_00437 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
FFNDPMCA_00438 2.3e-273 P Sodium:sulfate symporter transmembrane region
FFNDPMCA_00439 1.7e-153 ydjP I Alpha/beta hydrolase family
FFNDPMCA_00440 9.1e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FFNDPMCA_00441 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
FFNDPMCA_00442 4.1e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
FFNDPMCA_00443 4.9e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
FFNDPMCA_00444 9.3e-72 yeaL S Protein of unknown function (DUF441)
FFNDPMCA_00445 3.5e-21
FFNDPMCA_00446 3.6e-146 cbiQ P cobalt transport
FFNDPMCA_00447 0.0 ykoD P ABC transporter, ATP-binding protein
FFNDPMCA_00448 1.5e-95 S UPF0397 protein
FFNDPMCA_00449 2.9e-66 S Domain of unknown function DUF1828
FFNDPMCA_00450 5.5e-09
FFNDPMCA_00451 1.5e-50
FFNDPMCA_00452 2.6e-177 citR K Putative sugar-binding domain
FFNDPMCA_00453 6.5e-249 yjjP S Putative threonine/serine exporter
FFNDPMCA_00455 5.9e-37 M domain protein
FFNDPMCA_00456 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FFNDPMCA_00457 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
FFNDPMCA_00458 8.5e-60
FFNDPMCA_00459 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FFNDPMCA_00460 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FFNDPMCA_00461 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
FFNDPMCA_00462 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
FFNDPMCA_00463 9.8e-222 patA 2.6.1.1 E Aminotransferase
FFNDPMCA_00464 1.9e-109 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
FFNDPMCA_00465 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component
FFNDPMCA_00466 3.8e-103 potB E Binding-protein-dependent transport system inner membrane component
FFNDPMCA_00467 4e-98 rihB 3.2.2.1 F Nucleoside
FFNDPMCA_00468 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FFNDPMCA_00469 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
FFNDPMCA_00470 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FFNDPMCA_00471 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FFNDPMCA_00472 9.2e-201 tnpB L Putative transposase DNA-binding domain
FFNDPMCA_00473 4.2e-84 yqeG S HAD phosphatase, family IIIA
FFNDPMCA_00474 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
FFNDPMCA_00475 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FFNDPMCA_00476 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
FFNDPMCA_00477 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FFNDPMCA_00478 4.6e-216 ylbM S Belongs to the UPF0348 family
FFNDPMCA_00479 4.7e-97 yceD S Uncharacterized ACR, COG1399
FFNDPMCA_00480 1.2e-126 K response regulator
FFNDPMCA_00481 3.4e-278 arlS 2.7.13.3 T Histidine kinase
FFNDPMCA_00482 1e-12
FFNDPMCA_00483 1.5e-97 S CAAX protease self-immunity
FFNDPMCA_00484 6.1e-224 S SLAP domain
FFNDPMCA_00485 5.7e-83 S Aminoacyl-tRNA editing domain
FFNDPMCA_00486 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FFNDPMCA_00487 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
FFNDPMCA_00488 7.7e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFNDPMCA_00489 4.5e-58 yodB K Transcriptional regulator, HxlR family
FFNDPMCA_00491 8.3e-24 papP P ABC transporter, permease protein
FFNDPMCA_00492 1.4e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
FFNDPMCA_00493 1.9e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
FFNDPMCA_00494 7.5e-214 yubA S AI-2E family transporter
FFNDPMCA_00495 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FFNDPMCA_00496 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
FFNDPMCA_00497 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
FFNDPMCA_00498 2.6e-222 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
FFNDPMCA_00499 1.8e-234 S Peptidase M16
FFNDPMCA_00500 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
FFNDPMCA_00501 2e-96 ymfM S Helix-turn-helix domain
FFNDPMCA_00502 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFNDPMCA_00503 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FFNDPMCA_00504 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
FFNDPMCA_00505 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
FFNDPMCA_00506 2.5e-118 yvyE 3.4.13.9 S YigZ family
FFNDPMCA_00507 5.2e-245 comFA L Helicase C-terminal domain protein
FFNDPMCA_00508 2.9e-133 comFC S Competence protein
FFNDPMCA_00509 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FFNDPMCA_00510 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FFNDPMCA_00511 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FFNDPMCA_00512 5.1e-17
FFNDPMCA_00513 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FFNDPMCA_00514 3.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FFNDPMCA_00515 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
FFNDPMCA_00516 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FFNDPMCA_00517 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
FFNDPMCA_00518 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FFNDPMCA_00519 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FFNDPMCA_00520 1.1e-90 S Short repeat of unknown function (DUF308)
FFNDPMCA_00521 6.2e-165 rapZ S Displays ATPase and GTPase activities
FFNDPMCA_00522 4.3e-47 ybhK S Required for morphogenesis under gluconeogenic growth conditions
FFNDPMCA_00523 8.9e-130 ybhK S Required for morphogenesis under gluconeogenic growth conditions
FFNDPMCA_00524 2.1e-171 whiA K May be required for sporulation
FFNDPMCA_00525 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FFNDPMCA_00526 0.0 S SH3-like domain
FFNDPMCA_00527 9.3e-278 K Putative DNA-binding domain
FFNDPMCA_00528 2.9e-238 pyrP F Permease
FFNDPMCA_00529 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FFNDPMCA_00530 7.8e-261 emrY EGP Major facilitator Superfamily
FFNDPMCA_00531 4.3e-217 mdtG EGP Major facilitator Superfamily
FFNDPMCA_00536 4.5e-49 Q DNA (cytosine-5-)-methyltransferase activity
FFNDPMCA_00547 2.6e-21 radC L DNA repair protein
FFNDPMCA_00548 2.7e-15 K Transcriptional regulator
FFNDPMCA_00549 5.4e-32 K Helix-turn-helix domain
FFNDPMCA_00550 5.4e-45 S ERF superfamily
FFNDPMCA_00551 1.6e-48 S Protein of unknown function (DUF1351)
FFNDPMCA_00555 1.9e-10
FFNDPMCA_00557 4e-24 S Domain of unknown function (DUF771)
FFNDPMCA_00558 4.1e-15 K Helix-turn-helix XRE-family like proteins
FFNDPMCA_00559 2.6e-18 K Helix-turn-helix XRE-family like proteins
FFNDPMCA_00560 5.5e-07 S Pfam:DUF955
FFNDPMCA_00562 4.1e-153 L Belongs to the 'phage' integrase family
FFNDPMCA_00570 1e-25 S Domain of unknown function (DUF771)
FFNDPMCA_00571 9e-21 K Conserved phage C-terminus (Phg_2220_C)
FFNDPMCA_00573 4.1e-09 S Arc-like DNA binding domain
FFNDPMCA_00575 2.6e-31 K Helix-turn-helix domain
FFNDPMCA_00576 9e-22 XK27_07105 K Helix-turn-helix XRE-family like proteins
FFNDPMCA_00577 1.2e-23 K Helix-turn-helix domain
FFNDPMCA_00578 5e-08 S Pfam:DUF955
FFNDPMCA_00579 1.4e-153 L Belongs to the 'phage' integrase family
FFNDPMCA_00581 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFNDPMCA_00582 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
FFNDPMCA_00583 1.6e-21
FFNDPMCA_00584 9.4e-76 comGF U Putative Competence protein ComGF
FFNDPMCA_00585 8.6e-41
FFNDPMCA_00586 7.4e-71
FFNDPMCA_00587 3.1e-43 comGC U competence protein ComGC
FFNDPMCA_00588 1.7e-171 comGB NU type II secretion system
FFNDPMCA_00589 1.7e-179 comGA NU Type II IV secretion system protein
FFNDPMCA_00590 8.9e-133 yebC K Transcriptional regulatory protein
FFNDPMCA_00591 5.8e-94 S VanZ like family
FFNDPMCA_00592 3.5e-101 ylbE GM NAD(P)H-binding
FFNDPMCA_00593 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFNDPMCA_00595 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFNDPMCA_00596 9.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFNDPMCA_00597 1.1e-12 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
FFNDPMCA_00598 1.2e-116 mmuP E amino acid
FFNDPMCA_00599 3.2e-272 pepV 3.5.1.18 E dipeptidase PepV
FFNDPMCA_00600 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
FFNDPMCA_00601 3.2e-283 E Amino acid permease
FFNDPMCA_00602 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
FFNDPMCA_00603 1.5e-244 ynbB 4.4.1.1 P aluminum resistance
FFNDPMCA_00604 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
FFNDPMCA_00605 9.9e-82 C Flavodoxin
FFNDPMCA_00606 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FFNDPMCA_00607 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
FFNDPMCA_00608 2.3e-167 cvfB S S1 domain
FFNDPMCA_00609 2.9e-165 xerD D recombinase XerD
FFNDPMCA_00610 6.7e-30 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FFNDPMCA_00611 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FFNDPMCA_00612 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FFNDPMCA_00613 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FFNDPMCA_00614 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FFNDPMCA_00615 2.7e-18 M Lysin motif
FFNDPMCA_00616 5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
FFNDPMCA_00617 1.4e-24 rpsA 1.17.7.4 J Ribosomal protein S1
FFNDPMCA_00618 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
FFNDPMCA_00619 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FFNDPMCA_00620 8.7e-229 S Tetratricopeptide repeat protein
FFNDPMCA_00621 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFNDPMCA_00622 3.1e-148 glcU U sugar transport
FFNDPMCA_00623 7.1e-46
FFNDPMCA_00624 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
FFNDPMCA_00625 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
FFNDPMCA_00626 1.1e-36 S Alpha beta hydrolase
FFNDPMCA_00627 2.3e-65 S Alpha beta hydrolase
FFNDPMCA_00628 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
FFNDPMCA_00629 8.2e-85 scrR K Periplasmic binding protein domain
FFNDPMCA_00630 1.1e-90 ybbL S ABC transporter, ATP-binding protein
FFNDPMCA_00631 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
FFNDPMCA_00632 1.6e-94 S Domain of unknown function (DUF4811)
FFNDPMCA_00633 1.8e-262 lmrB EGP Major facilitator Superfamily
FFNDPMCA_00634 3.2e-77 K MerR HTH family regulatory protein
FFNDPMCA_00635 4.7e-117 cylA V ABC transporter
FFNDPMCA_00636 4.7e-93 cylB V ABC-2 type transporter
FFNDPMCA_00637 2.5e-45 K LytTr DNA-binding domain
FFNDPMCA_00638 9.9e-33 S Protein of unknown function (DUF3021)
FFNDPMCA_00639 4.7e-140 S Cysteine-rich secretory protein family
FFNDPMCA_00640 6.6e-273 ycaM E amino acid
FFNDPMCA_00641 9.2e-289
FFNDPMCA_00643 2.6e-189 cggR K Putative sugar-binding domain
FFNDPMCA_00644 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FFNDPMCA_00645 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
FFNDPMCA_00646 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FFNDPMCA_00647 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
FFNDPMCA_00648 1.2e-94
FFNDPMCA_00649 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
FFNDPMCA_00650 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FFNDPMCA_00651 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
FFNDPMCA_00652 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
FFNDPMCA_00653 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
FFNDPMCA_00654 2e-163 murB 1.3.1.98 M Cell wall formation
FFNDPMCA_00655 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
FFNDPMCA_00656 1.9e-128 potB P ABC transporter permease
FFNDPMCA_00657 4.8e-127 potC P ABC transporter permease
FFNDPMCA_00658 7.3e-208 potD P ABC transporter
FFNDPMCA_00659 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FFNDPMCA_00660 2e-172 ybbR S YbbR-like protein
FFNDPMCA_00661 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FFNDPMCA_00662 1.4e-147 S hydrolase
FFNDPMCA_00663 3e-75 K Penicillinase repressor
FFNDPMCA_00664 1.6e-118
FFNDPMCA_00665 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFNDPMCA_00666 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
FFNDPMCA_00667 8.3e-143 licT K CAT RNA binding domain
FFNDPMCA_00668 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
FFNDPMCA_00669 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FFNDPMCA_00670 1e-149 D Alpha beta
FFNDPMCA_00671 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
FFNDPMCA_00672 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
FFNDPMCA_00673 1.6e-116 ica2 GT2 M Glycosyl transferase family group 2
FFNDPMCA_00674 8.2e-36
FFNDPMCA_00675 1.1e-76 2.7.7.65 T GGDEF domain
FFNDPMCA_00676 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFNDPMCA_00678 1.2e-145 S Metal-independent alpha-mannosidase (GH125)
FFNDPMCA_00679 3.8e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
FFNDPMCA_00680 2.1e-285 lsa S ABC transporter
FFNDPMCA_00681 2.4e-44
FFNDPMCA_00682 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
FFNDPMCA_00683 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
FFNDPMCA_00684 9.7e-52 S Iron-sulfur cluster assembly protein
FFNDPMCA_00685 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
FFNDPMCA_00686 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
FFNDPMCA_00687 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
FFNDPMCA_00688 4.3e-75
FFNDPMCA_00689 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FFNDPMCA_00690 1.3e-168 dnaI L Primosomal protein DnaI
FFNDPMCA_00691 3.3e-250 dnaB L Replication initiation and membrane attachment
FFNDPMCA_00692 3.9e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FFNDPMCA_00693 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FFNDPMCA_00694 2.7e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FFNDPMCA_00695 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFNDPMCA_00696 3.8e-30
FFNDPMCA_00697 2e-29
FFNDPMCA_00698 7.8e-157 S reductase
FFNDPMCA_00699 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
FFNDPMCA_00700 9.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FFNDPMCA_00701 3.2e-181 ccpA K catabolite control protein A
FFNDPMCA_00702 2.6e-266 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FFNDPMCA_00703 4.3e-55
FFNDPMCA_00704 1.2e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
FFNDPMCA_00705 8.3e-105 yutD S Protein of unknown function (DUF1027)
FFNDPMCA_00706 6.9e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FFNDPMCA_00707 3.7e-100 S Protein of unknown function (DUF1461)
FFNDPMCA_00708 2.3e-116 dedA S SNARE-like domain protein
FFNDPMCA_00709 8e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
FFNDPMCA_00710 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
FFNDPMCA_00711 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
FFNDPMCA_00712 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
FFNDPMCA_00713 3.5e-71 yqeY S YqeY-like protein
FFNDPMCA_00714 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
FFNDPMCA_00715 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFNDPMCA_00716 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FFNDPMCA_00717 9.2e-15
FFNDPMCA_00719 1.2e-37 S VRR_NUC
FFNDPMCA_00728 7.1e-98 L Helix-turn-helix domain
FFNDPMCA_00729 1.2e-135 S ERF superfamily
FFNDPMCA_00730 4.2e-129 S Protein of unknown function (DUF1351)
FFNDPMCA_00731 4.6e-45
FFNDPMCA_00733 5.5e-18
FFNDPMCA_00734 1.8e-31 S Helix-turn-helix domain
FFNDPMCA_00740 9.2e-93 S DNA binding
FFNDPMCA_00741 6.1e-18 K Helix-turn-helix XRE-family like proteins
FFNDPMCA_00742 1.2e-22 K Cro/C1-type HTH DNA-binding domain
FFNDPMCA_00743 3.7e-12 E Zn peptidase
FFNDPMCA_00745 6.2e-12
FFNDPMCA_00746 2.6e-94 sip L Belongs to the 'phage' integrase family
FFNDPMCA_00747 6.4e-09 dps P Belongs to the Dps family
FFNDPMCA_00748 1.2e-30 copZ C Heavy-metal-associated domain
FFNDPMCA_00749 1e-284 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
FFNDPMCA_00750 1.9e-30 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
FFNDPMCA_00751 6.3e-26 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
FFNDPMCA_00752 7.3e-173 MA20_14895 S Conserved hypothetical protein 698
FFNDPMCA_00754 1.6e-61
FFNDPMCA_00755 3.3e-250 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FFNDPMCA_00756 3.2e-71 S Domain of unknown function (DUF3284)
FFNDPMCA_00757 1e-300 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FFNDPMCA_00758 5e-120 gmuR K UTRA
FFNDPMCA_00759 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FFNDPMCA_00760 5.8e-274 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FFNDPMCA_00761 9.2e-137 ypbG 2.7.1.2 GK ROK family
FFNDPMCA_00762 1.2e-85 C nitroreductase
FFNDPMCA_00763 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
FFNDPMCA_00764 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
FFNDPMCA_00765 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FFNDPMCA_00766 0.0 lacZ 3.2.1.23 G -beta-galactosidase
FFNDPMCA_00767 2.6e-103 lacS G Transporter
FFNDPMCA_00768 3.3e-194 ampC V Beta-lactamase
FFNDPMCA_00771 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
FFNDPMCA_00772 1.3e-113 tdk 2.7.1.21 F thymidine kinase
FFNDPMCA_00773 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FFNDPMCA_00774 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FFNDPMCA_00775 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FFNDPMCA_00776 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FFNDPMCA_00777 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
FFNDPMCA_00778 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFNDPMCA_00779 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FFNDPMCA_00780 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFNDPMCA_00781 2.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FFNDPMCA_00782 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FFNDPMCA_00783 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FFNDPMCA_00784 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
FFNDPMCA_00785 2e-30 ywzB S Protein of unknown function (DUF1146)
FFNDPMCA_00786 1.2e-177 mbl D Cell shape determining protein MreB Mrl
FFNDPMCA_00787 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
FFNDPMCA_00788 3.3e-33 S Protein of unknown function (DUF2969)
FFNDPMCA_00789 1.4e-215 rodA D Belongs to the SEDS family
FFNDPMCA_00790 2.3e-78 usp6 T universal stress protein
FFNDPMCA_00791 8.4e-39
FFNDPMCA_00792 2.2e-238 rarA L recombination factor protein RarA
FFNDPMCA_00793 1.3e-84 yueI S Protein of unknown function (DUF1694)
FFNDPMCA_00794 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFNDPMCA_00795 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FFNDPMCA_00796 8.2e-213 iscS2 2.8.1.7 E Aminotransferase class V
FFNDPMCA_00797 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFNDPMCA_00798 1.9e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
FFNDPMCA_00799 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FFNDPMCA_00800 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
FFNDPMCA_00801 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
FFNDPMCA_00802 6.2e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
FFNDPMCA_00803 1.5e-94 S Protein of unknown function (DUF3990)
FFNDPMCA_00804 2.9e-44
FFNDPMCA_00806 0.0 3.6.3.8 P P-type ATPase
FFNDPMCA_00807 5.6e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
FFNDPMCA_00808 2.5e-52
FFNDPMCA_00809 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FFNDPMCA_00810 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FFNDPMCA_00811 5.7e-126 S Haloacid dehalogenase-like hydrolase
FFNDPMCA_00812 2.3e-108 radC L DNA repair protein
FFNDPMCA_00813 2.4e-176 mreB D cell shape determining protein MreB
FFNDPMCA_00814 2e-147 mreC M Involved in formation and maintenance of cell shape
FFNDPMCA_00815 1.3e-93 mreD
FFNDPMCA_00817 6.4e-54 S Protein of unknown function (DUF3397)
FFNDPMCA_00818 6.3e-78 mraZ K Belongs to the MraZ family
FFNDPMCA_00819 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FFNDPMCA_00820 1.8e-54 ftsL D Cell division protein FtsL
FFNDPMCA_00821 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
FFNDPMCA_00822 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFNDPMCA_00823 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FFNDPMCA_00824 5.7e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFNDPMCA_00825 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FFNDPMCA_00826 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FFNDPMCA_00827 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFNDPMCA_00828 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FFNDPMCA_00829 1.7e-45 yggT S YGGT family
FFNDPMCA_00830 5.7e-149 ylmH S S4 domain protein
FFNDPMCA_00831 2.8e-74 gpsB D DivIVA domain protein
FFNDPMCA_00832 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FFNDPMCA_00833 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
FFNDPMCA_00834 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
FFNDPMCA_00835 6.7e-37
FFNDPMCA_00836 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFNDPMCA_00837 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
FFNDPMCA_00838 5.4e-56 XK27_04120 S Putative amino acid metabolism
FFNDPMCA_00839 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FFNDPMCA_00840 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
FFNDPMCA_00841 8.3e-106 S Repeat protein
FFNDPMCA_00842 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FFNDPMCA_00843 1.3e-293 L Nuclease-related domain
FFNDPMCA_00844 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
FFNDPMCA_00845 4e-60 L Resolvase, N terminal domain
FFNDPMCA_00846 4.6e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFNDPMCA_00847 2.3e-101 L An automated process has identified a potential problem with this gene model
FFNDPMCA_00848 3.4e-131 infB M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)