ORF_ID e_value Gene_name EC_number CAZy COGs Description
DCFIPOFO_00001 4.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
DCFIPOFO_00002 7.2e-197 ampC V Beta-lactamase
DCFIPOFO_00005 1.4e-72
DCFIPOFO_00006 2e-205 EGP Major facilitator Superfamily
DCFIPOFO_00007 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
DCFIPOFO_00008 1.4e-107 vanZ V VanZ like family
DCFIPOFO_00009 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DCFIPOFO_00010 5.3e-270 T PhoQ Sensor
DCFIPOFO_00011 9e-130 K Transcriptional regulatory protein, C terminal
DCFIPOFO_00012 9.2e-68 S SdpI/YhfL protein family
DCFIPOFO_00013 2.9e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
DCFIPOFO_00014 1.8e-80 patB 4.4.1.8 E Aminotransferase, class I
DCFIPOFO_00015 1e-76 M Protein of unknown function (DUF3737)
DCFIPOFO_00016 2.1e-226 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
DCFIPOFO_00017 1.8e-47 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
DCFIPOFO_00018 3.1e-132 sip L Belongs to the 'phage' integrase family
DCFIPOFO_00019 7.3e-13 S sequence-specific DNA binding
DCFIPOFO_00020 4.8e-20
DCFIPOFO_00022 1.5e-10
DCFIPOFO_00024 2.9e-28
DCFIPOFO_00025 1.9e-35 S Primase C terminal 1 (PriCT-1)
DCFIPOFO_00026 1.4e-84 S DNA primase
DCFIPOFO_00029 5e-09
DCFIPOFO_00031 2.8e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DCFIPOFO_00032 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
DCFIPOFO_00033 4.7e-88 comGF U Putative Competence protein ComGF
DCFIPOFO_00034 3.9e-08
DCFIPOFO_00035 3.7e-67
DCFIPOFO_00036 1.1e-36 comGC U Required for transformation and DNA binding
DCFIPOFO_00037 4.7e-177 comGB NU type II secretion system
DCFIPOFO_00038 5.8e-180 comGA NU Type II IV secretion system protein
DCFIPOFO_00039 1.5e-132 yebC K Transcriptional regulatory protein
DCFIPOFO_00040 7.3e-97 S VanZ like family
DCFIPOFO_00041 3.7e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DCFIPOFO_00042 4.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
DCFIPOFO_00043 8.5e-150 yisY 1.11.1.10 S Alpha/beta hydrolase family
DCFIPOFO_00044 4.8e-115
DCFIPOFO_00045 3.1e-178 S Putative adhesin
DCFIPOFO_00046 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCFIPOFO_00047 2.3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCFIPOFO_00048 3.8e-148 S Sucrose-6F-phosphate phosphohydrolase
DCFIPOFO_00049 2.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCFIPOFO_00050 8.1e-174 ybbR S YbbR-like protein
DCFIPOFO_00051 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DCFIPOFO_00052 1.3e-209 potD P ABC transporter
DCFIPOFO_00053 8.5e-137 potC P ABC transporter permease
DCFIPOFO_00054 2.7e-130 potB P ABC transporter permease
DCFIPOFO_00055 2.5e-203 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DCFIPOFO_00056 4.4e-166 murB 1.3.1.98 M Cell wall formation
DCFIPOFO_00057 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
DCFIPOFO_00058 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
DCFIPOFO_00059 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DCFIPOFO_00060 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DCFIPOFO_00061 8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
DCFIPOFO_00062 2.9e-93
DCFIPOFO_00063 6.6e-91
DCFIPOFO_00065 1e-107 3.2.2.20 K acetyltransferase
DCFIPOFO_00066 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DCFIPOFO_00067 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DCFIPOFO_00068 2.5e-28 secG U Preprotein translocase
DCFIPOFO_00069 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DCFIPOFO_00070 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DCFIPOFO_00071 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DCFIPOFO_00072 1.6e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DCFIPOFO_00073 2.3e-187 cggR K Putative sugar-binding domain
DCFIPOFO_00075 1.2e-277 ycaM E amino acid
DCFIPOFO_00076 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DCFIPOFO_00077 6.2e-171 whiA K May be required for sporulation
DCFIPOFO_00078 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DCFIPOFO_00079 6e-160 rapZ S Displays ATPase and GTPase activities
DCFIPOFO_00080 1.1e-90 S Short repeat of unknown function (DUF308)
DCFIPOFO_00081 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DCFIPOFO_00082 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DCFIPOFO_00083 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DCFIPOFO_00084 1.6e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DCFIPOFO_00085 5.2e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DCFIPOFO_00086 1.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DCFIPOFO_00087 9.2e-181 lacR K Transcriptional regulator
DCFIPOFO_00088 5.5e-112 tdk 2.7.1.21 F thymidine kinase
DCFIPOFO_00089 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DCFIPOFO_00090 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DCFIPOFO_00091 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DCFIPOFO_00092 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DCFIPOFO_00093 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
DCFIPOFO_00094 2.1e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCFIPOFO_00095 5.9e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DCFIPOFO_00096 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCFIPOFO_00097 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DCFIPOFO_00098 3.1e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DCFIPOFO_00099 3.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DCFIPOFO_00100 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DCFIPOFO_00101 2e-30 ywzB S Protein of unknown function (DUF1146)
DCFIPOFO_00102 2.2e-179 mbl D Cell shape determining protein MreB Mrl
DCFIPOFO_00103 2.5e-15 S DNA-directed RNA polymerase subunit beta
DCFIPOFO_00104 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DCFIPOFO_00105 1.3e-34 S Protein of unknown function (DUF2969)
DCFIPOFO_00106 3.6e-224 rodA D Belongs to the SEDS family
DCFIPOFO_00107 5.2e-81 usp6 T universal stress protein
DCFIPOFO_00109 7.4e-239 rarA L recombination factor protein RarA
DCFIPOFO_00110 1e-81 yueI S Protein of unknown function (DUF1694)
DCFIPOFO_00111 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DCFIPOFO_00113 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DCFIPOFO_00114 2.4e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DCFIPOFO_00115 2.3e-223 cpdA S Calcineurin-like phosphoesterase
DCFIPOFO_00116 2.2e-173 degV S DegV family
DCFIPOFO_00117 9.9e-58
DCFIPOFO_00118 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DCFIPOFO_00119 2.3e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DCFIPOFO_00120 1.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DCFIPOFO_00121 2.8e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DCFIPOFO_00122 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
DCFIPOFO_00123 0.0 FbpA K Fibronectin-binding protein
DCFIPOFO_00124 3.8e-64
DCFIPOFO_00125 8.5e-162 degV S EDD domain protein, DegV family
DCFIPOFO_00126 3.7e-151
DCFIPOFO_00127 6.7e-167 K Transcriptional regulator
DCFIPOFO_00128 4.9e-204 xerS L Belongs to the 'phage' integrase family
DCFIPOFO_00129 3e-34 ykzG S Belongs to the UPF0356 family
DCFIPOFO_00130 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DCFIPOFO_00131 9.9e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DCFIPOFO_00132 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DCFIPOFO_00133 5.1e-116 S Repeat protein
DCFIPOFO_00134 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DCFIPOFO_00135 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DCFIPOFO_00136 1.6e-57 XK27_04120 S Putative amino acid metabolism
DCFIPOFO_00137 3.3e-214 iscS 2.8.1.7 E Aminotransferase class V
DCFIPOFO_00138 1.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DCFIPOFO_00140 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
DCFIPOFO_00141 2e-32 cspA K 'Cold-shock' DNA-binding domain
DCFIPOFO_00142 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DCFIPOFO_00143 2.1e-119 gpsB D DivIVA domain protein
DCFIPOFO_00144 4.8e-148 ylmH S S4 domain protein
DCFIPOFO_00145 2e-27 yggT S YGGT family
DCFIPOFO_00146 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DCFIPOFO_00147 4.9e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DCFIPOFO_00148 2.7e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DCFIPOFO_00149 6.3e-154 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DCFIPOFO_00150 3.6e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DCFIPOFO_00151 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DCFIPOFO_00152 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DCFIPOFO_00153 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
DCFIPOFO_00154 6.3e-55 ftsL D Cell division protein FtsL
DCFIPOFO_00155 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DCFIPOFO_00156 4.1e-77 mraZ K Belongs to the MraZ family
DCFIPOFO_00157 6.1e-52 S Protein of unknown function (DUF3397)
DCFIPOFO_00158 3.6e-13 S Protein of unknown function (DUF4044)
DCFIPOFO_00159 5.4e-95 mreD
DCFIPOFO_00160 1e-143 mreC M Involved in formation and maintenance of cell shape
DCFIPOFO_00161 6.4e-166 mreB D cell shape determining protein MreB
DCFIPOFO_00162 9.5e-112 radC L DNA repair protein
DCFIPOFO_00163 9.2e-124 S Haloacid dehalogenase-like hydrolase
DCFIPOFO_00164 2.8e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DCFIPOFO_00165 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DCFIPOFO_00166 0.0 3.6.3.8 P P-type ATPase
DCFIPOFO_00167 4.2e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DCFIPOFO_00168 7.8e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DCFIPOFO_00169 5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DCFIPOFO_00170 7.8e-216 iscS2 2.8.1.7 E Aminotransferase class V
DCFIPOFO_00171 1.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DCFIPOFO_00172 7.2e-68
DCFIPOFO_00173 1.6e-64 S Domain of unknown function DUF1828
DCFIPOFO_00174 7.4e-88 S Rib/alpha-like repeat
DCFIPOFO_00175 7.7e-247 yagE E amino acid
DCFIPOFO_00176 5.1e-116 GM NmrA-like family
DCFIPOFO_00177 1.9e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
DCFIPOFO_00178 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
DCFIPOFO_00179 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DCFIPOFO_00180 3.9e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DCFIPOFO_00181 0.0 oatA I Acyltransferase
DCFIPOFO_00182 1.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DCFIPOFO_00183 9.3e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DCFIPOFO_00184 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
DCFIPOFO_00185 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DCFIPOFO_00186 9e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
DCFIPOFO_00187 2.1e-28 S Protein of unknown function (DUF2929)
DCFIPOFO_00188 0.0 dnaE 2.7.7.7 L DNA polymerase
DCFIPOFO_00189 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DCFIPOFO_00190 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DCFIPOFO_00191 1.5e-166 cvfB S S1 domain
DCFIPOFO_00192 2.5e-169 xerD D recombinase XerD
DCFIPOFO_00193 3.1e-62 ribT K acetyltransferase
DCFIPOFO_00194 1.1e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DCFIPOFO_00195 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DCFIPOFO_00196 1.8e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DCFIPOFO_00197 1.9e-58 M Lysin motif
DCFIPOFO_00198 3.8e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DCFIPOFO_00199 1.4e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DCFIPOFO_00200 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
DCFIPOFO_00201 9.4e-242 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DCFIPOFO_00202 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DCFIPOFO_00203 1.1e-231 S Tetratricopeptide repeat protein
DCFIPOFO_00204 6e-61 yugI 5.3.1.9 J general stress protein
DCFIPOFO_00205 4.8e-179 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
DCFIPOFO_00206 2.7e-117 dedA S SNARE-like domain protein
DCFIPOFO_00207 8.6e-105 S Protein of unknown function (DUF1461)
DCFIPOFO_00208 3.6e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DCFIPOFO_00209 9.1e-98 yutD S Protein of unknown function (DUF1027)
DCFIPOFO_00210 3.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DCFIPOFO_00211 2e-55
DCFIPOFO_00212 8e-268 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DCFIPOFO_00213 2.4e-275 pepV 3.5.1.18 E dipeptidase PepV
DCFIPOFO_00214 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
DCFIPOFO_00215 3.6e-177 ccpA K catabolite control protein A
DCFIPOFO_00216 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DCFIPOFO_00217 4e-51
DCFIPOFO_00219 2e-158 ykuT M mechanosensitive ion channel
DCFIPOFO_00220 5.9e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DCFIPOFO_00221 2.2e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DCFIPOFO_00222 6.5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DCFIPOFO_00223 2.4e-68 yslB S Protein of unknown function (DUF2507)
DCFIPOFO_00224 6.6e-53 trxA O Belongs to the thioredoxin family
DCFIPOFO_00225 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DCFIPOFO_00226 1.6e-91 cvpA S Colicin V production protein
DCFIPOFO_00227 1.8e-50 yrzB S Belongs to the UPF0473 family
DCFIPOFO_00228 1.4e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DCFIPOFO_00229 2.6e-42 yrzL S Belongs to the UPF0297 family
DCFIPOFO_00230 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DCFIPOFO_00231 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DCFIPOFO_00232 6.6e-184 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
DCFIPOFO_00233 1.4e-209 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DCFIPOFO_00234 1.1e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DCFIPOFO_00235 4.5e-31 yajC U Preprotein translocase
DCFIPOFO_00236 1.4e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DCFIPOFO_00237 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DCFIPOFO_00238 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DCFIPOFO_00239 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DCFIPOFO_00240 0.0 nisT V ABC transporter
DCFIPOFO_00241 2.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
DCFIPOFO_00242 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DCFIPOFO_00243 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DCFIPOFO_00244 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DCFIPOFO_00245 5.5e-135 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DCFIPOFO_00246 1.1e-136 cdsA 2.7.7.41 S Belongs to the CDS family
DCFIPOFO_00247 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DCFIPOFO_00248 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DCFIPOFO_00249 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DCFIPOFO_00250 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
DCFIPOFO_00251 1.1e-217 nusA K Participates in both transcription termination and antitermination
DCFIPOFO_00252 2e-46 ylxR K Protein of unknown function (DUF448)
DCFIPOFO_00253 6e-46 rplGA J ribosomal protein
DCFIPOFO_00254 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DCFIPOFO_00255 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DCFIPOFO_00256 5.2e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DCFIPOFO_00257 7.6e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DCFIPOFO_00258 1.6e-282 lsa S ABC transporter
DCFIPOFO_00259 6.7e-121 S GyrI-like small molecule binding domain
DCFIPOFO_00260 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DCFIPOFO_00261 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DCFIPOFO_00262 0.0 dnaK O Heat shock 70 kDa protein
DCFIPOFO_00263 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DCFIPOFO_00264 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DCFIPOFO_00265 9.3e-124 srtA 3.4.22.70 M sortase family
DCFIPOFO_00266 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
DCFIPOFO_00267 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCFIPOFO_00268 1.1e-278 yjeM E Amino Acid
DCFIPOFO_00269 9.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DCFIPOFO_00270 9.4e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DCFIPOFO_00271 1.6e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DCFIPOFO_00272 3e-251 G Major Facilitator
DCFIPOFO_00273 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
DCFIPOFO_00274 1.4e-158 lysR5 K LysR substrate binding domain
DCFIPOFO_00276 5.2e-25 S PFAM Archaeal ATPase
DCFIPOFO_00277 2.1e-241 pyrP F Permease
DCFIPOFO_00278 1.3e-137 lacR K DeoR C terminal sensor domain
DCFIPOFO_00279 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
DCFIPOFO_00280 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
DCFIPOFO_00281 1.6e-128 S Domain of unknown function (DUF4867)
DCFIPOFO_00282 7.2e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DCFIPOFO_00283 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
DCFIPOFO_00284 1.4e-267 gatC G PTS system sugar-specific permease component
DCFIPOFO_00285 1.3e-38
DCFIPOFO_00286 1e-148 lacT K CAT RNA binding domain
DCFIPOFO_00287 2.5e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
DCFIPOFO_00288 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
DCFIPOFO_00289 4.8e-292 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
DCFIPOFO_00290 1e-201 S PFAM Archaeal ATPase
DCFIPOFO_00291 8.2e-165 K LysR family
DCFIPOFO_00292 0.0 1.3.5.4 C FMN_bind
DCFIPOFO_00293 8.3e-260 P Sodium:sulfate symporter transmembrane region
DCFIPOFO_00294 5.7e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
DCFIPOFO_00295 3.3e-112 3.6.1.27 I Acid phosphatase homologues
DCFIPOFO_00296 1.9e-217 mdtG EGP Major facilitator Superfamily
DCFIPOFO_00297 1.5e-32
DCFIPOFO_00298 6.1e-73 K helix_turn_helix multiple antibiotic resistance protein
DCFIPOFO_00299 5.8e-82
DCFIPOFO_00300 2.7e-210 pepA E M42 glutamyl aminopeptidase
DCFIPOFO_00302 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
DCFIPOFO_00303 1.2e-103 G PTS system sorbose-specific iic component
DCFIPOFO_00304 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
DCFIPOFO_00305 6.8e-72 2.7.1.191 G PTS system fructose IIA component
DCFIPOFO_00306 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DCFIPOFO_00307 8.2e-182 lacI3 K helix_turn _helix lactose operon repressor
DCFIPOFO_00308 4.4e-224 3.2.1.177 GH31 G Glycosyl hydrolases family 31
DCFIPOFO_00309 2.1e-170 3.2.1.177 GH31 G Glycosyl hydrolases family 31
DCFIPOFO_00310 1.6e-266 dtpT U amino acid peptide transporter
DCFIPOFO_00311 2.9e-208 naiP EGP Major facilitator Superfamily
DCFIPOFO_00312 3.8e-79 S Alpha beta hydrolase
DCFIPOFO_00313 1.8e-64 S Alpha beta hydrolase
DCFIPOFO_00314 4.6e-76 K Transcriptional regulator, MarR family
DCFIPOFO_00315 2.1e-52 XK27_09600 V ABC transporter, ATP-binding protein
DCFIPOFO_00316 7.1e-248 XK27_09600 V ABC transporter, ATP-binding protein
DCFIPOFO_00317 0.0 V ABC transporter transmembrane region
DCFIPOFO_00318 1.3e-148 glnH ET ABC transporter
DCFIPOFO_00319 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DCFIPOFO_00320 9.1e-150 glnH ET ABC transporter
DCFIPOFO_00321 7.8e-109 gluC P ABC transporter permease
DCFIPOFO_00322 2e-107 glnP P ABC transporter permease
DCFIPOFO_00323 2.4e-150 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DCFIPOFO_00324 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
DCFIPOFO_00325 1.1e-130 treR K UTRA
DCFIPOFO_00326 0.0 treB 2.7.1.211 G phosphotransferase system
DCFIPOFO_00327 8.3e-84 S Putative adhesin
DCFIPOFO_00328 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
DCFIPOFO_00329 1.9e-205 EGP Major facilitator superfamily
DCFIPOFO_00331 1.6e-35 S Enterocin A Immunity
DCFIPOFO_00332 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
DCFIPOFO_00333 5.7e-160 rssA S Phospholipase, patatin family
DCFIPOFO_00334 2.4e-257 glnPH2 P ABC transporter permease
DCFIPOFO_00335 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DCFIPOFO_00336 6.2e-96 K Acetyltransferase (GNAT) domain
DCFIPOFO_00337 1.3e-159 pstS P Phosphate
DCFIPOFO_00338 2.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
DCFIPOFO_00339 8.3e-157 pstA P Phosphate transport system permease protein PstA
DCFIPOFO_00340 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DCFIPOFO_00341 2.7e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DCFIPOFO_00342 2.6e-118 phoU P Plays a role in the regulation of phosphate uptake
DCFIPOFO_00343 1.7e-282 S C4-dicarboxylate anaerobic carrier
DCFIPOFO_00344 5.8e-85 dps P Belongs to the Dps family
DCFIPOFO_00346 3.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCFIPOFO_00347 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DCFIPOFO_00348 4.1e-175 rihB 3.2.2.1 F Nucleoside
DCFIPOFO_00349 4e-133 gntR K UbiC transcription regulator-associated domain protein
DCFIPOFO_00350 2e-52 S Enterocin A Immunity
DCFIPOFO_00351 1.8e-116 glcR K DeoR C terminal sensor domain
DCFIPOFO_00352 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
DCFIPOFO_00353 1.6e-120 C nitroreductase
DCFIPOFO_00354 1.1e-132
DCFIPOFO_00355 3.6e-252 yhdP S Transporter associated domain
DCFIPOFO_00356 2.8e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DCFIPOFO_00357 5e-235 potE E amino acid
DCFIPOFO_00358 2.6e-137 M Glycosyl hydrolases family 25
DCFIPOFO_00359 4.1e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
DCFIPOFO_00360 2.1e-249 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DCFIPOFO_00363 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DCFIPOFO_00364 4.4e-86 gtcA S Teichoic acid glycosylation protein
DCFIPOFO_00365 4.2e-77 fld C Flavodoxin
DCFIPOFO_00366 7.4e-160 map 3.4.11.18 E Methionine Aminopeptidase
DCFIPOFO_00367 1.6e-166 yihY S Belongs to the UPF0761 family
DCFIPOFO_00368 8.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DCFIPOFO_00369 3e-153 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DCFIPOFO_00370 4.4e-180 E ABC transporter, ATP-binding protein
DCFIPOFO_00371 1.6e-288 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DCFIPOFO_00372 6.9e-66 O OsmC-like protein
DCFIPOFO_00373 8.3e-21 ltrA S Bacterial low temperature requirement A protein (LtrA)
DCFIPOFO_00374 1.9e-112 2.7.6.5 T Region found in RelA / SpoT proteins
DCFIPOFO_00375 5.3e-116 K response regulator
DCFIPOFO_00376 1.6e-233 sptS 2.7.13.3 T Histidine kinase
DCFIPOFO_00377 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DCFIPOFO_00378 1e-19
DCFIPOFO_00379 4.2e-50
DCFIPOFO_00380 0.0 pepN 3.4.11.2 E aminopeptidase
DCFIPOFO_00381 2.5e-141 S haloacid dehalogenase-like hydrolase
DCFIPOFO_00382 5.2e-122 S CAAX protease self-immunity
DCFIPOFO_00384 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DCFIPOFO_00385 6.6e-72
DCFIPOFO_00386 2.1e-108 fic D Fic/DOC family
DCFIPOFO_00387 1.8e-225 I transferase activity, transferring acyl groups other than amino-acyl groups
DCFIPOFO_00388 3.5e-128 pnb C nitroreductase
DCFIPOFO_00389 7.1e-98 S Domain of unknown function (DUF4811)
DCFIPOFO_00390 1.8e-265 lmrB EGP Major facilitator Superfamily
DCFIPOFO_00391 1.2e-76 K MerR HTH family regulatory protein
DCFIPOFO_00392 0.0 oppA E ABC transporter substrate-binding protein
DCFIPOFO_00393 8.6e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
DCFIPOFO_00394 4.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
DCFIPOFO_00395 2.1e-168 2.7.1.2 GK ROK family
DCFIPOFO_00396 3.6e-165 rhaS6 K helix_turn_helix, arabinose operon control protein
DCFIPOFO_00397 2.7e-63 I Carboxylesterase family
DCFIPOFO_00398 6.9e-83 I Carboxylesterase family
DCFIPOFO_00399 2.2e-189 yhjX P Major Facilitator Superfamily
DCFIPOFO_00400 2.5e-306 S Predicted membrane protein (DUF2207)
DCFIPOFO_00401 5.2e-56 K Acetyltransferase (GNAT) domain
DCFIPOFO_00402 1.4e-59
DCFIPOFO_00403 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DCFIPOFO_00404 1.2e-92 S ECF-type riboflavin transporter, S component
DCFIPOFO_00405 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DCFIPOFO_00406 1.2e-12
DCFIPOFO_00407 6.3e-246 S Uncharacterized protein conserved in bacteria (DUF2325)
DCFIPOFO_00408 1.2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DCFIPOFO_00409 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
DCFIPOFO_00410 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
DCFIPOFO_00411 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DCFIPOFO_00412 9.5e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DCFIPOFO_00413 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DCFIPOFO_00414 2.2e-73 yqhY S Asp23 family, cell envelope-related function
DCFIPOFO_00415 8e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DCFIPOFO_00416 8.1e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DCFIPOFO_00417 3.6e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DCFIPOFO_00418 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DCFIPOFO_00419 3.9e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DCFIPOFO_00420 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DCFIPOFO_00421 1.7e-264 recN L May be involved in recombinational repair of damaged DNA
DCFIPOFO_00422 1.8e-47
DCFIPOFO_00423 4.7e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DCFIPOFO_00424 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DCFIPOFO_00425 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DCFIPOFO_00426 7.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DCFIPOFO_00427 1.2e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DCFIPOFO_00428 4.5e-140 stp 3.1.3.16 T phosphatase
DCFIPOFO_00429 0.0 KLT serine threonine protein kinase
DCFIPOFO_00430 1.4e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DCFIPOFO_00431 5.3e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DCFIPOFO_00432 1e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
DCFIPOFO_00433 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DCFIPOFO_00434 1.4e-57 asp S Asp23 family, cell envelope-related function
DCFIPOFO_00435 9.6e-308 yloV S DAK2 domain fusion protein YloV
DCFIPOFO_00436 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DCFIPOFO_00437 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DCFIPOFO_00438 2.2e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DCFIPOFO_00439 1.1e-192 oppD P Belongs to the ABC transporter superfamily
DCFIPOFO_00440 4.4e-180 oppF P Belongs to the ABC transporter superfamily
DCFIPOFO_00441 7.5e-180 oppB P ABC transporter permease
DCFIPOFO_00442 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
DCFIPOFO_00443 3.2e-30 oppA E ABC transporter substrate-binding protein
DCFIPOFO_00444 2.8e-298 oppA E ABC transporter substrate-binding protein
DCFIPOFO_00445 0.0 oppA E ABC transporter substrate-binding protein
DCFIPOFO_00446 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DCFIPOFO_00447 0.0 smc D Required for chromosome condensation and partitioning
DCFIPOFO_00448 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DCFIPOFO_00449 6.1e-287 pipD E Dipeptidase
DCFIPOFO_00450 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DCFIPOFO_00451 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DCFIPOFO_00452 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DCFIPOFO_00453 7.4e-97 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DCFIPOFO_00454 2.2e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DCFIPOFO_00455 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DCFIPOFO_00456 9.3e-118 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DCFIPOFO_00457 6.5e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
DCFIPOFO_00458 1.1e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
DCFIPOFO_00459 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DCFIPOFO_00460 1.5e-34 ynzC S UPF0291 protein
DCFIPOFO_00461 1.5e-30 yneF S Uncharacterised protein family (UPF0154)
DCFIPOFO_00462 0.0 mdlA V ABC transporter
DCFIPOFO_00463 6.1e-300 mdlB V ABC transporter
DCFIPOFO_00464 8.6e-201 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DCFIPOFO_00465 9.8e-117 plsC 2.3.1.51 I Acyltransferase
DCFIPOFO_00466 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
DCFIPOFO_00467 9.5e-119 ybhL S Belongs to the BI1 family
DCFIPOFO_00468 2.3e-105 4.1.1.45 S Amidohydrolase
DCFIPOFO_00469 1.5e-33 4.1.1.45 S Amidohydrolase
DCFIPOFO_00470 6.8e-245 yrvN L AAA C-terminal domain
DCFIPOFO_00471 7.3e-58 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
DCFIPOFO_00472 1.3e-53 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
DCFIPOFO_00473 2.5e-86 XK27_09675 K Acetyltransferase (GNAT) domain
DCFIPOFO_00474 7.9e-69 ogt 2.1.1.63 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
DCFIPOFO_00475 6.2e-76 K Transcriptional regulator
DCFIPOFO_00476 5.5e-50 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
DCFIPOFO_00477 6.9e-80 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
DCFIPOFO_00478 2.1e-96 K Acetyltransferase (GNAT) family
DCFIPOFO_00479 1.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
DCFIPOFO_00480 1.4e-93 dps P Belongs to the Dps family
DCFIPOFO_00481 4.6e-35 copZ C Heavy-metal-associated domain
DCFIPOFO_00482 8.4e-242 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
DCFIPOFO_00483 5.5e-50 K LytTr DNA-binding domain
DCFIPOFO_00484 2.4e-68 S pyridoxamine 5-phosphate
DCFIPOFO_00485 2.9e-78 yobV1 K WYL domain
DCFIPOFO_00486 1.3e-70 yobV1 K WYL domain
DCFIPOFO_00487 4.1e-30 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
DCFIPOFO_00488 6.6e-63 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DCFIPOFO_00489 4.1e-264 npr 1.11.1.1 C NADH oxidase
DCFIPOFO_00490 1.9e-32 G Major facilitator Superfamily
DCFIPOFO_00491 4.9e-61 S Sulfite exporter TauE/SafE
DCFIPOFO_00492 1.2e-89 mdt(A) EGP Major facilitator Superfamily
DCFIPOFO_00493 7.2e-88 mdt(A) EGP Major facilitator Superfamily
DCFIPOFO_00494 2.1e-117 GM NAD(P)H-binding
DCFIPOFO_00495 1.7e-231 E Alpha/beta hydrolase of unknown function (DUF1100)
DCFIPOFO_00496 9.2e-101 K Transcriptional regulator C-terminal region
DCFIPOFO_00498 1.1e-155 C Aldo keto reductase
DCFIPOFO_00499 3.9e-126 lmrA 3.6.3.44 V ABC transporter
DCFIPOFO_00500 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
DCFIPOFO_00501 1.7e-32 mta K helix_turn_helix, mercury resistance
DCFIPOFO_00502 4.4e-35 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
DCFIPOFO_00503 3.1e-189 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DCFIPOFO_00504 1.2e-50 yphH S Cupin domain
DCFIPOFO_00505 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DCFIPOFO_00506 0.0 typA T GTP-binding protein TypA
DCFIPOFO_00507 2.5e-209 ftsW D Belongs to the SEDS family
DCFIPOFO_00508 7.9e-52 ylbG S UPF0298 protein
DCFIPOFO_00509 1.6e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
DCFIPOFO_00510 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DCFIPOFO_00511 2.5e-186 ylbL T Belongs to the peptidase S16 family
DCFIPOFO_00512 2.4e-79 comEA L Competence protein ComEA
DCFIPOFO_00513 4.2e-106 ypsA S Belongs to the UPF0398 family
DCFIPOFO_00514 1.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DCFIPOFO_00515 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
DCFIPOFO_00516 1.2e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DCFIPOFO_00517 6.7e-116 dnaD L DnaD domain protein
DCFIPOFO_00518 2.9e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
DCFIPOFO_00519 4.8e-90 ypmB S Protein conserved in bacteria
DCFIPOFO_00520 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DCFIPOFO_00521 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DCFIPOFO_00522 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DCFIPOFO_00523 1.3e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
DCFIPOFO_00524 3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DCFIPOFO_00525 4.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
DCFIPOFO_00526 5.2e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DCFIPOFO_00527 1.6e-272 V ABC-type multidrug transport system, ATPase and permease components
DCFIPOFO_00528 9.5e-289 V ABC-type multidrug transport system, ATPase and permease components
DCFIPOFO_00529 1.4e-158 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
DCFIPOFO_00530 6.1e-160 rbsU U ribose uptake protein RbsU
DCFIPOFO_00531 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DCFIPOFO_00532 1.8e-83 6.3.3.2 S ASCH
DCFIPOFO_00533 1.6e-137 2.4.2.3 F Phosphorylase superfamily
DCFIPOFO_00534 2.6e-88 2.3.1.57 K Acetyltransferase (GNAT) family
DCFIPOFO_00535 1.4e-98 rimL J Acetyltransferase (GNAT) domain
DCFIPOFO_00536 2.5e-43
DCFIPOFO_00537 2.7e-51 S endonuclease activity
DCFIPOFO_00538 3.6e-151 S Fic/DOC family
DCFIPOFO_00539 6e-143 3.1.3.48 T Tyrosine phosphatase family
DCFIPOFO_00541 1.4e-135
DCFIPOFO_00542 2.1e-63
DCFIPOFO_00543 1.6e-48 S MazG-like family
DCFIPOFO_00544 1.9e-152 S Protein of unknown function (DUF2785)
DCFIPOFO_00545 1.2e-22 K Acetyltransferase (GNAT) domain
DCFIPOFO_00546 4.5e-36 K Acetyltransferase (GNAT) domain
DCFIPOFO_00547 1.1e-48
DCFIPOFO_00548 5e-282 V ABC transporter transmembrane region
DCFIPOFO_00549 1.7e-84 C nitroreductase
DCFIPOFO_00550 2e-294 V ABC-type multidrug transport system, ATPase and permease components
DCFIPOFO_00551 2.6e-149 ropB K Helix-turn-helix domain
DCFIPOFO_00552 1.6e-128 qmcA O prohibitin homologues
DCFIPOFO_00553 1.2e-141 S Protein of unknown function (DUF975)
DCFIPOFO_00554 1.3e-54 K sequence-specific DNA binding
DCFIPOFO_00555 1e-09 K sequence-specific DNA binding
DCFIPOFO_00556 2e-105 speG J Acetyltransferase (GNAT) domain
DCFIPOFO_00557 2.2e-139
DCFIPOFO_00558 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
DCFIPOFO_00559 2e-42 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
DCFIPOFO_00560 8.4e-50
DCFIPOFO_00561 2.8e-28
DCFIPOFO_00562 8.4e-119 drgA C nitroreductase
DCFIPOFO_00563 0.0 1.3.5.4 C FMN_bind
DCFIPOFO_00564 1.1e-167 lysR7 K LysR substrate binding domain
DCFIPOFO_00565 3.3e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DCFIPOFO_00566 2.7e-230 hom1 1.1.1.3 E homoserine dehydrogenase
DCFIPOFO_00567 9.5e-283 thrC 4.2.3.1 E Threonine synthase
DCFIPOFO_00568 2.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DCFIPOFO_00569 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
DCFIPOFO_00570 0.0 pepO 3.4.24.71 O Peptidase family M13
DCFIPOFO_00571 0.0 XK27_06780 V ABC transporter permease
DCFIPOFO_00572 2.9e-128 XK27_06785 V ABC transporter, ATP-binding protein
DCFIPOFO_00573 5.7e-126 alkD L DNA alkylation repair enzyme
DCFIPOFO_00574 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DCFIPOFO_00575 3.6e-27 pncA Q Isochorismatase family
DCFIPOFO_00576 3.3e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DCFIPOFO_00577 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DCFIPOFO_00578 1.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DCFIPOFO_00579 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DCFIPOFO_00580 2.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DCFIPOFO_00581 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DCFIPOFO_00582 6.8e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DCFIPOFO_00583 1.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DCFIPOFO_00584 2.7e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DCFIPOFO_00585 2.3e-303 I Protein of unknown function (DUF2974)
DCFIPOFO_00586 5.1e-153 yxeH S hydrolase
DCFIPOFO_00587 1.7e-161 XK27_05540 S DUF218 domain
DCFIPOFO_00588 3.5e-52 ybjQ S Belongs to the UPF0145 family
DCFIPOFO_00589 7.4e-229 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
DCFIPOFO_00590 1.1e-167
DCFIPOFO_00591 4e-133
DCFIPOFO_00592 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DCFIPOFO_00593 8.1e-22
DCFIPOFO_00594 2.3e-108
DCFIPOFO_00595 2.1e-138
DCFIPOFO_00596 3.3e-124 skfE V ATPases associated with a variety of cellular activities
DCFIPOFO_00597 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
DCFIPOFO_00598 1.4e-245 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DCFIPOFO_00599 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DCFIPOFO_00600 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
DCFIPOFO_00601 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DCFIPOFO_00602 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DCFIPOFO_00603 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DCFIPOFO_00604 3.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DCFIPOFO_00605 1.6e-137 recO L Involved in DNA repair and RecF pathway recombination
DCFIPOFO_00606 1.6e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DCFIPOFO_00607 1.2e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DCFIPOFO_00608 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
DCFIPOFO_00609 4.1e-40 yqeY S YqeY-like protein
DCFIPOFO_00610 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DCFIPOFO_00611 1e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DCFIPOFO_00612 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DCFIPOFO_00613 3.8e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCFIPOFO_00614 2.4e-144 E GDSL-like Lipase/Acylhydrolase family
DCFIPOFO_00615 2.3e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DCFIPOFO_00616 1.4e-223 patA 2.6.1.1 E Aminotransferase
DCFIPOFO_00617 3.5e-31
DCFIPOFO_00618 7.2e-164 htpX O Peptidase family M48
DCFIPOFO_00620 4.5e-76 S HIRAN
DCFIPOFO_00622 3.3e-180 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DCFIPOFO_00623 2.5e-121 frnE Q DSBA-like thioredoxin domain
DCFIPOFO_00624 2.2e-224
DCFIPOFO_00625 1.2e-70 S Domain of unknown function (DUF4767)
DCFIPOFO_00626 7.4e-78
DCFIPOFO_00627 6.7e-89 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DCFIPOFO_00628 1.2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
DCFIPOFO_00629 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DCFIPOFO_00630 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DCFIPOFO_00631 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DCFIPOFO_00632 7.7e-160
DCFIPOFO_00633 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DCFIPOFO_00634 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DCFIPOFO_00635 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
DCFIPOFO_00636 1.2e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
DCFIPOFO_00637 0.0 comEC S Competence protein ComEC
DCFIPOFO_00639 2.2e-102 3.6.1.27 I Acid phosphatase homologues
DCFIPOFO_00640 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DCFIPOFO_00641 3.7e-18 S Sugar efflux transporter for intercellular exchange
DCFIPOFO_00642 1.1e-310 ybiT S ABC transporter, ATP-binding protein
DCFIPOFO_00643 2.7e-41 K Helix-turn-helix domain
DCFIPOFO_00644 2.8e-146 F DNA/RNA non-specific endonuclease
DCFIPOFO_00645 7.6e-60 L nuclease
DCFIPOFO_00646 1.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
DCFIPOFO_00647 1.6e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DCFIPOFO_00648 2.8e-67 metI P ABC transporter permease
DCFIPOFO_00649 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DCFIPOFO_00650 2.1e-260 frdC 1.3.5.4 C FAD binding domain
DCFIPOFO_00651 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DCFIPOFO_00652 2.2e-257 yjjP S Putative threonine/serine exporter
DCFIPOFO_00653 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
DCFIPOFO_00654 0.0 aha1 P E1-E2 ATPase
DCFIPOFO_00655 0.0 S Bacterial membrane protein, YfhO
DCFIPOFO_00656 3e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DCFIPOFO_00657 4.6e-174 prmA J Ribosomal protein L11 methyltransferase
DCFIPOFO_00658 1.4e-65
DCFIPOFO_00659 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DCFIPOFO_00660 7.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DCFIPOFO_00661 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
DCFIPOFO_00662 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DCFIPOFO_00663 3.1e-73
DCFIPOFO_00664 1.5e-82 mutT 3.6.1.55 F NUDIX domain
DCFIPOFO_00665 5.8e-35
DCFIPOFO_00666 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DCFIPOFO_00667 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DCFIPOFO_00668 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DCFIPOFO_00669 9.8e-191 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DCFIPOFO_00670 3.5e-91 yqeG S HAD phosphatase, family IIIA
DCFIPOFO_00671 4.7e-210 yqeH S Ribosome biogenesis GTPase YqeH
DCFIPOFO_00672 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DCFIPOFO_00673 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
DCFIPOFO_00674 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DCFIPOFO_00675 2.2e-218 ylbM S Belongs to the UPF0348 family
DCFIPOFO_00676 2.9e-96 yceD S Uncharacterized ACR, COG1399
DCFIPOFO_00677 1.1e-130 K response regulator
DCFIPOFO_00678 1.9e-281 arlS 2.7.13.3 T Histidine kinase
DCFIPOFO_00679 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DCFIPOFO_00680 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DCFIPOFO_00681 9.6e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCFIPOFO_00682 7.3e-64 yodB K Transcriptional regulator, HxlR family
DCFIPOFO_00683 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DCFIPOFO_00684 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DCFIPOFO_00685 2.9e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DCFIPOFO_00686 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DCFIPOFO_00687 0.0 S membrane
DCFIPOFO_00688 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
DCFIPOFO_00689 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DCFIPOFO_00690 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DCFIPOFO_00691 4.5e-118 gluP 3.4.21.105 S Rhomboid family
DCFIPOFO_00692 6e-35 yqgQ S Bacterial protein of unknown function (DUF910)
DCFIPOFO_00693 1.5e-57 yqhL P Rhodanese-like protein
DCFIPOFO_00694 1.1e-18 S Protein of unknown function (DUF3042)
DCFIPOFO_00695 9.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DCFIPOFO_00696 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
DCFIPOFO_00697 2.8e-205 EGP Major facilitator Superfamily
DCFIPOFO_00698 4.3e-152 S haloacid dehalogenase-like hydrolase
DCFIPOFO_00699 2.4e-07
DCFIPOFO_00700 8.1e-179 D Alpha beta
DCFIPOFO_00701 6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
DCFIPOFO_00702 3.9e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
DCFIPOFO_00703 2.9e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
DCFIPOFO_00704 9.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DCFIPOFO_00705 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
DCFIPOFO_00706 2.4e-112 ygaC J Belongs to the UPF0374 family
DCFIPOFO_00707 4.9e-90
DCFIPOFO_00708 3e-78
DCFIPOFO_00709 1.6e-157 hlyX S Transporter associated domain
DCFIPOFO_00710 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DCFIPOFO_00711 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
DCFIPOFO_00712 0.0 clpE O Belongs to the ClpA ClpB family
DCFIPOFO_00713 6.9e-26
DCFIPOFO_00714 1.2e-39 ptsH G phosphocarrier protein HPR
DCFIPOFO_00715 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DCFIPOFO_00716 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DCFIPOFO_00717 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DCFIPOFO_00718 1.7e-162 coiA 3.6.4.12 S Competence protein
DCFIPOFO_00719 7e-107 yjbH Q Thioredoxin
DCFIPOFO_00720 3.3e-112 yjbK S CYTH
DCFIPOFO_00721 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
DCFIPOFO_00722 5.2e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DCFIPOFO_00723 3.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DCFIPOFO_00724 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
DCFIPOFO_00725 3.9e-234 N Uncharacterized conserved protein (DUF2075)
DCFIPOFO_00726 4.8e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
DCFIPOFO_00727 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
DCFIPOFO_00728 5.4e-212 yubA S AI-2E family transporter
DCFIPOFO_00729 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DCFIPOFO_00730 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
DCFIPOFO_00731 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DCFIPOFO_00732 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DCFIPOFO_00733 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DCFIPOFO_00734 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DCFIPOFO_00735 3.8e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DCFIPOFO_00736 2.5e-35
DCFIPOFO_00737 6.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DCFIPOFO_00738 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DCFIPOFO_00739 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DCFIPOFO_00740 5.7e-126 comFC S Competence protein
DCFIPOFO_00741 1.1e-242 comFA L Helicase C-terminal domain protein
DCFIPOFO_00742 2.5e-118 yvyE 3.4.13.9 S YigZ family
DCFIPOFO_00743 2.7e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
DCFIPOFO_00744 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
DCFIPOFO_00745 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DCFIPOFO_00746 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DCFIPOFO_00747 4.3e-125 ymfM S Helix-turn-helix domain
DCFIPOFO_00748 1.6e-129 IQ Enoyl-(Acyl carrier protein) reductase
DCFIPOFO_00749 8.3e-232 S Peptidase M16
DCFIPOFO_00750 5.9e-219 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
DCFIPOFO_00751 7.2e-124 yoaK S Protein of unknown function (DUF1275)
DCFIPOFO_00752 7.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DCFIPOFO_00753 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DCFIPOFO_00754 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
DCFIPOFO_00755 2.2e-179 K Transcriptional regulator
DCFIPOFO_00756 6.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DCFIPOFO_00757 4.8e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DCFIPOFO_00758 4.1e-130 ymfC K UTRA
DCFIPOFO_00759 8.2e-254 3.5.1.18 E Peptidase family M20/M25/M40
DCFIPOFO_00760 3.3e-180 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
DCFIPOFO_00761 2.9e-93 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
DCFIPOFO_00762 2.4e-197 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DCFIPOFO_00763 1.2e-117 cutC P Participates in the control of copper homeostasis
DCFIPOFO_00764 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DCFIPOFO_00765 1.4e-75 K UTRA
DCFIPOFO_00766 5.9e-12
DCFIPOFO_00767 4e-69 rmaI K Transcriptional regulator
DCFIPOFO_00768 1.4e-211 EGP Major facilitator Superfamily
DCFIPOFO_00769 5.7e-230 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
DCFIPOFO_00770 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DCFIPOFO_00771 1.1e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DCFIPOFO_00772 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DCFIPOFO_00773 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DCFIPOFO_00774 2.3e-251 dnaB L Replication initiation and membrane attachment
DCFIPOFO_00775 2.7e-163 dnaI L Primosomal protein DnaI
DCFIPOFO_00776 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DCFIPOFO_00777 1.4e-72 K LytTr DNA-binding domain
DCFIPOFO_00778 1.9e-74 S Protein of unknown function (DUF3021)
DCFIPOFO_00779 4.8e-171 V ABC transporter
DCFIPOFO_00780 1.3e-131 S domain protein
DCFIPOFO_00781 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DCFIPOFO_00782 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DCFIPOFO_00783 8.9e-116 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DCFIPOFO_00784 2.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
DCFIPOFO_00785 1.8e-124 magIII L Base excision DNA repair protein, HhH-GPD family
DCFIPOFO_00786 3.3e-166 akr5f 1.1.1.346 S reductase
DCFIPOFO_00787 1.1e-74 C Aldo/keto reductase family
DCFIPOFO_00788 2.9e-14 C Aldo/keto reductase family
DCFIPOFO_00789 4.1e-147 S hydrolase
DCFIPOFO_00790 3.2e-103 yagU S Protein of unknown function (DUF1440)
DCFIPOFO_00791 1.2e-143 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
DCFIPOFO_00792 3.5e-307 KL domain protein
DCFIPOFO_00793 1.4e-122 KL domain protein
DCFIPOFO_00794 2.6e-134
DCFIPOFO_00795 1.8e-292 hsdM 2.1.1.72 V type I restriction-modification system
DCFIPOFO_00796 1.6e-224 3.1.21.3 V Type I restriction modification DNA specificity domain
DCFIPOFO_00797 2.4e-178 L Belongs to the 'phage' integrase family
DCFIPOFO_00798 1.3e-209 3.1.21.3 V Type I restriction modification DNA specificity domain
DCFIPOFO_00799 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
DCFIPOFO_00800 0.0 S Protein of unknown function DUF262
DCFIPOFO_00801 0.0 1.3.5.4 C FMN_bind
DCFIPOFO_00802 7.2e-92
DCFIPOFO_00803 9.2e-109
DCFIPOFO_00804 3.8e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DCFIPOFO_00805 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DCFIPOFO_00806 7.6e-115 hlyIII S protein, hemolysin III
DCFIPOFO_00807 3.8e-151 DegV S Uncharacterised protein, DegV family COG1307
DCFIPOFO_00808 2e-35 yozE S Belongs to the UPF0346 family
DCFIPOFO_00809 1.1e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
DCFIPOFO_00810 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DCFIPOFO_00811 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DCFIPOFO_00812 5.8e-152 dprA LU DNA protecting protein DprA
DCFIPOFO_00813 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCFIPOFO_00814 1.8e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DCFIPOFO_00815 2e-169 xerC D Phage integrase, N-terminal SAM-like domain
DCFIPOFO_00816 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DCFIPOFO_00817 2e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DCFIPOFO_00818 4.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
DCFIPOFO_00819 2.6e-98 K LysR substrate binding domain
DCFIPOFO_00820 6.1e-97 S LexA-binding, inner membrane-associated putative hydrolase
DCFIPOFO_00821 1.2e-63
DCFIPOFO_00822 1.1e-179 MA20_14895 S Conserved hypothetical protein 698
DCFIPOFO_00823 5.9e-70 K Transcriptional regulator
DCFIPOFO_00824 5.4e-47
DCFIPOFO_00825 2.6e-42
DCFIPOFO_00826 1.8e-41 K peptidyl-tyrosine sulfation
DCFIPOFO_00827 1.7e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DCFIPOFO_00828 2e-74 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DCFIPOFO_00830 2.1e-109 ybbL S ABC transporter, ATP-binding protein
DCFIPOFO_00831 9.6e-130 ybbM S Uncharacterised protein family (UPF0014)
DCFIPOFO_00832 2.1e-96 K Acetyltransferase (GNAT) domain
DCFIPOFO_00833 3.7e-51 S Protein of unknown function (DUF3021)
DCFIPOFO_00834 8.7e-75 K LytTr DNA-binding domain
DCFIPOFO_00835 6.2e-104 S Protein of unknown function (DUF1211)
DCFIPOFO_00836 6.3e-193 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DCFIPOFO_00837 5.6e-228 G Major Facilitator Superfamily
DCFIPOFO_00838 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DCFIPOFO_00839 3.3e-211 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DCFIPOFO_00840 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
DCFIPOFO_00841 1.7e-34
DCFIPOFO_00842 4.2e-98 yvrI K sigma factor activity
DCFIPOFO_00843 2.7e-290 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
DCFIPOFO_00844 7.5e-292 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
DCFIPOFO_00845 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
DCFIPOFO_00846 2e-152 lacT K PRD domain
DCFIPOFO_00847 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCFIPOFO_00848 1.7e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DCFIPOFO_00849 3.4e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DCFIPOFO_00850 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCFIPOFO_00851 1.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DCFIPOFO_00852 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
DCFIPOFO_00853 4.8e-257 pepC 3.4.22.40 E Peptidase C1-like family
DCFIPOFO_00854 2.6e-185 S AAA domain
DCFIPOFO_00855 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DCFIPOFO_00856 5.4e-26
DCFIPOFO_00857 2e-42
DCFIPOFO_00858 3.4e-155 czcD P cation diffusion facilitator family transporter
DCFIPOFO_00859 2.6e-52 K Transcriptional regulator, ArsR family
DCFIPOFO_00860 1.3e-128 pgm3 G Belongs to the phosphoglycerate mutase family
DCFIPOFO_00861 3.8e-110 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
DCFIPOFO_00862 1.2e-160 1.6.5.2 GM NmrA-like family
DCFIPOFO_00863 1.2e-79
DCFIPOFO_00864 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
DCFIPOFO_00865 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DCFIPOFO_00866 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DCFIPOFO_00867 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DCFIPOFO_00868 3.2e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DCFIPOFO_00869 5.1e-156 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DCFIPOFO_00870 1.3e-61 rplQ J Ribosomal protein L17
DCFIPOFO_00871 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DCFIPOFO_00872 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DCFIPOFO_00873 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DCFIPOFO_00874 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DCFIPOFO_00875 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DCFIPOFO_00876 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DCFIPOFO_00877 1.3e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DCFIPOFO_00878 1.3e-70 rplO J Binds to the 23S rRNA
DCFIPOFO_00879 1.4e-23 rpmD J Ribosomal protein L30
DCFIPOFO_00880 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DCFIPOFO_00881 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DCFIPOFO_00882 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DCFIPOFO_00883 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DCFIPOFO_00884 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DCFIPOFO_00885 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DCFIPOFO_00886 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DCFIPOFO_00887 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DCFIPOFO_00888 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DCFIPOFO_00889 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
DCFIPOFO_00890 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DCFIPOFO_00891 3.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DCFIPOFO_00892 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DCFIPOFO_00893 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DCFIPOFO_00894 5.6e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DCFIPOFO_00895 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DCFIPOFO_00896 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
DCFIPOFO_00897 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DCFIPOFO_00898 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
DCFIPOFO_00899 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DCFIPOFO_00900 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DCFIPOFO_00901 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DCFIPOFO_00902 2.4e-108 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DCFIPOFO_00903 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DCFIPOFO_00904 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DCFIPOFO_00905 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DCFIPOFO_00907 1.6e-08
DCFIPOFO_00908 5e-235 V ABC-type multidrug transport system, ATPase and permease components
DCFIPOFO_00909 3.2e-292 P ABC transporter
DCFIPOFO_00910 3e-76 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
DCFIPOFO_00911 2.5e-11 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
DCFIPOFO_00912 5.1e-231 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
DCFIPOFO_00913 2.7e-48
DCFIPOFO_00914 5.2e-68 K HxlR family
DCFIPOFO_00915 4.5e-17 L Plasmid pRiA4b ORF-3-like protein
DCFIPOFO_00916 2.9e-70 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DCFIPOFO_00917 1.4e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DCFIPOFO_00918 9.2e-248 brnQ U Component of the transport system for branched-chain amino acids
DCFIPOFO_00919 5.8e-63 S Putative adhesin
DCFIPOFO_00920 3.9e-113 3.6.1.55 F NUDIX domain
DCFIPOFO_00921 1.8e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DCFIPOFO_00922 2.4e-301
DCFIPOFO_00923 0.0 M domain protein
DCFIPOFO_00924 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
DCFIPOFO_00925 3.9e-23 bamA UW LPXTG-motif cell wall anchor domain protein
DCFIPOFO_00927 0.0 S domain, Protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)