ORF_ID e_value Gene_name EC_number CAZy COGs Description
NHFGHKIH_00001 3.2e-101 3.6.1.27 I Acid phosphatase homologues
NHFGHKIH_00002 2.1e-146 yitS S Uncharacterised protein, DegV family COG1307
NHFGHKIH_00003 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHFGHKIH_00004 1.9e-70 S Domain of unknown function (DUF4767)
NHFGHKIH_00005 1.8e-73 C nitroreductase
NHFGHKIH_00006 2.7e-141 L An automated process has identified a potential problem with this gene model
NHFGHKIH_00007 6.8e-156 ypbG 2.7.1.2 GK ROK family
NHFGHKIH_00008 3.9e-128 S CAAX protease self-immunity
NHFGHKIH_00009 8e-224 S SLAP domain
NHFGHKIH_00010 1.2e-54 S Abi-like protein
NHFGHKIH_00011 1.5e-72 S Aminoacyl-tRNA editing domain
NHFGHKIH_00012 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHFGHKIH_00013 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NHFGHKIH_00014 5e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHFGHKIH_00015 8.8e-62 yodB K Transcriptional regulator, HxlR family
NHFGHKIH_00017 9.6e-110 papP P ABC transporter, permease protein
NHFGHKIH_00018 2e-110 P ABC transporter permease
NHFGHKIH_00019 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHFGHKIH_00020 3e-53 cjaA ET ABC transporter substrate-binding protein
NHFGHKIH_00021 8.1e-91 cjaA ET ABC transporter substrate-binding protein
NHFGHKIH_00022 2.4e-128 S cog cog1373
NHFGHKIH_00023 1.4e-109 yniG EGP Major facilitator Superfamily
NHFGHKIH_00024 5.4e-237 L transposase, IS605 OrfB family
NHFGHKIH_00025 1.2e-76 yniG EGP Major facilitator Superfamily
NHFGHKIH_00026 4.9e-35
NHFGHKIH_00028 1.3e-42
NHFGHKIH_00029 1.9e-75 M LysM domain
NHFGHKIH_00030 8.7e-279 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHFGHKIH_00031 1.5e-102 srtA 3.4.22.70 M sortase family
NHFGHKIH_00032 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHFGHKIH_00033 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHFGHKIH_00034 0.0 dnaK O Heat shock 70 kDa protein
NHFGHKIH_00035 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHFGHKIH_00036 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHFGHKIH_00037 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NHFGHKIH_00038 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHFGHKIH_00039 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHFGHKIH_00040 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHFGHKIH_00041 3.2e-47 rplGA J ribosomal protein
NHFGHKIH_00042 8.8e-47 ylxR K Protein of unknown function (DUF448)
NHFGHKIH_00043 4.2e-196 nusA K Participates in both transcription termination and antitermination
NHFGHKIH_00044 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NHFGHKIH_00045 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHFGHKIH_00046 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHFGHKIH_00047 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NHFGHKIH_00048 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
NHFGHKIH_00049 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHFGHKIH_00050 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHFGHKIH_00051 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NHFGHKIH_00052 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHFGHKIH_00053 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NHFGHKIH_00054 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
NHFGHKIH_00055 2.9e-116 plsC 2.3.1.51 I Acyltransferase
NHFGHKIH_00056 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NHFGHKIH_00057 0.0 pepO 3.4.24.71 O Peptidase family M13
NHFGHKIH_00058 0.0 mdlB V ABC transporter
NHFGHKIH_00059 0.0 mdlA V ABC transporter
NHFGHKIH_00060 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
NHFGHKIH_00061 3e-38 ynzC S UPF0291 protein
NHFGHKIH_00062 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHFGHKIH_00063 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
NHFGHKIH_00064 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
NHFGHKIH_00065 4.6e-213 S SLAP domain
NHFGHKIH_00066 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHFGHKIH_00067 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NHFGHKIH_00068 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHFGHKIH_00069 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NHFGHKIH_00070 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHFGHKIH_00071 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHFGHKIH_00072 2.7e-258 yfnA E amino acid
NHFGHKIH_00073 0.0 V FtsX-like permease family
NHFGHKIH_00074 4.1e-133 cysA V ABC transporter, ATP-binding protein
NHFGHKIH_00075 3.4e-23
NHFGHKIH_00077 2.5e-288 pipD E Dipeptidase
NHFGHKIH_00078 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHFGHKIH_00079 0.0 smc D Required for chromosome condensation and partitioning
NHFGHKIH_00080 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHFGHKIH_00081 2.1e-308 oppA E ABC transporter substrate-binding protein
NHFGHKIH_00082 3.1e-240 oppA E ABC transporter substrate-binding protein
NHFGHKIH_00083 4e-57 K Helix-turn-helix domain
NHFGHKIH_00084 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHFGHKIH_00085 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
NHFGHKIH_00086 5.6e-183 K Transcriptional regulator
NHFGHKIH_00087 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHFGHKIH_00088 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHFGHKIH_00089 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHFGHKIH_00090 0.0 snf 2.7.11.1 KL domain protein
NHFGHKIH_00091 2e-35
NHFGHKIH_00093 3.8e-104 pncA Q Isochorismatase family
NHFGHKIH_00094 4.9e-118
NHFGHKIH_00097 3.6e-63
NHFGHKIH_00098 1.4e-34
NHFGHKIH_00099 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
NHFGHKIH_00100 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
NHFGHKIH_00101 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
NHFGHKIH_00102 3.6e-140 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NHFGHKIH_00103 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
NHFGHKIH_00104 1.2e-250 yifK E Amino acid permease
NHFGHKIH_00105 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHFGHKIH_00106 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHFGHKIH_00107 0.0 aha1 P E1-E2 ATPase
NHFGHKIH_00108 2.4e-175 F DNA/RNA non-specific endonuclease
NHFGHKIH_00109 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
NHFGHKIH_00110 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHFGHKIH_00111 3.4e-73 metI P ABC transporter permease
NHFGHKIH_00112 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHFGHKIH_00113 1.9e-261 frdC 1.3.5.4 C FAD binding domain
NHFGHKIH_00114 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHFGHKIH_00115 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
NHFGHKIH_00116 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
NHFGHKIH_00117 5.7e-272 P Sodium:sulfate symporter transmembrane region
NHFGHKIH_00118 1.7e-153 ydjP I Alpha/beta hydrolase family
NHFGHKIH_00119 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NHFGHKIH_00120 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
NHFGHKIH_00121 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NHFGHKIH_00122 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NHFGHKIH_00123 9.3e-72 yeaL S Protein of unknown function (DUF441)
NHFGHKIH_00124 3.5e-21
NHFGHKIH_00125 3.6e-146 cbiQ P cobalt transport
NHFGHKIH_00126 0.0 ykoD P ABC transporter, ATP-binding protein
NHFGHKIH_00127 1.5e-95 S UPF0397 protein
NHFGHKIH_00128 2.9e-66 S Domain of unknown function DUF1828
NHFGHKIH_00129 5.5e-09
NHFGHKIH_00130 1.5e-50
NHFGHKIH_00131 2.6e-177 citR K Putative sugar-binding domain
NHFGHKIH_00132 6.5e-249 yjjP S Putative threonine/serine exporter
NHFGHKIH_00134 5.9e-37 M domain protein
NHFGHKIH_00135 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHFGHKIH_00136 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
NHFGHKIH_00137 8.5e-60
NHFGHKIH_00138 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHFGHKIH_00139 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHFGHKIH_00140 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NHFGHKIH_00141 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHFGHKIH_00142 1.2e-222 patA 2.6.1.1 E Aminotransferase
NHFGHKIH_00143 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NHFGHKIH_00144 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
NHFGHKIH_00145 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NHFGHKIH_00146 1.7e-284 E Amino acid permease
NHFGHKIH_00147 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
NHFGHKIH_00148 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
NHFGHKIH_00149 1.4e-115 mmuP E amino acid
NHFGHKIH_00150 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NHFGHKIH_00151 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHFGHKIH_00152 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHFGHKIH_00153 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
NHFGHKIH_00154 1.4e-98 L Helix-turn-helix domain
NHFGHKIH_00155 5.3e-139 L hmm pf00665
NHFGHKIH_00156 2.9e-15 M LysM domain protein
NHFGHKIH_00157 3.8e-48 M LysM domain protein
NHFGHKIH_00158 1.4e-86 C Aldo keto reductase
NHFGHKIH_00159 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
NHFGHKIH_00160 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NHFGHKIH_00161 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NHFGHKIH_00162 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
NHFGHKIH_00163 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHFGHKIH_00164 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHFGHKIH_00165 5.8e-152 dprA LU DNA protecting protein DprA
NHFGHKIH_00166 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHFGHKIH_00167 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHFGHKIH_00168 1.9e-94 yjcE P Sodium proton antiporter
NHFGHKIH_00169 1.5e-40 yjcE P Sodium proton antiporter
NHFGHKIH_00170 1.1e-66 yjcE P NhaP-type Na H and K H
NHFGHKIH_00171 7.1e-36 yozE S Belongs to the UPF0346 family
NHFGHKIH_00172 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
NHFGHKIH_00173 1.2e-107 hlyIII S protein, hemolysin III
NHFGHKIH_00174 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHFGHKIH_00175 8.8e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHFGHKIH_00176 4.3e-86 3.4.21.96 S SLAP domain
NHFGHKIH_00177 2.9e-190 yagE E Amino acid permease
NHFGHKIH_00178 2.7e-83 S Protein of unknown function (DUF1211)
NHFGHKIH_00179 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
NHFGHKIH_00180 2.8e-119 3.6.1.55 F NUDIX domain
NHFGHKIH_00181 1.1e-245 brnQ U Component of the transport system for branched-chain amino acids
NHFGHKIH_00182 0.0 L Plasmid pRiA4b ORF-3-like protein
NHFGHKIH_00183 3.4e-27
NHFGHKIH_00184 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
NHFGHKIH_00185 5.4e-53 hipB K sequence-specific DNA binding
NHFGHKIH_00186 4.8e-42 S SnoaL-like domain
NHFGHKIH_00187 9.2e-262 emrY EGP Major facilitator Superfamily
NHFGHKIH_00188 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHFGHKIH_00189 7.6e-239 pyrP F Permease
NHFGHKIH_00190 1.9e-22 K Putative DNA-binding domain
NHFGHKIH_00191 2e-75 S cog cog0433
NHFGHKIH_00192 1.9e-110 F DNA/RNA non-specific endonuclease
NHFGHKIH_00193 2.7e-34 S YSIRK type signal peptide
NHFGHKIH_00195 5.5e-53
NHFGHKIH_00196 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NHFGHKIH_00197 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHFGHKIH_00198 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHFGHKIH_00199 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHFGHKIH_00200 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NHFGHKIH_00201 0.0 FbpA K Fibronectin-binding protein
NHFGHKIH_00202 1.1e-66
NHFGHKIH_00203 1.3e-159 degV S EDD domain protein, DegV family
NHFGHKIH_00204 1.2e-210 EGP Major facilitator Superfamily
NHFGHKIH_00205 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
NHFGHKIH_00206 1.1e-104 vanZ V VanZ like family
NHFGHKIH_00207 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHFGHKIH_00208 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
NHFGHKIH_00209 4.4e-129 K Transcriptional regulatory protein, C terminal
NHFGHKIH_00210 7.7e-67 S SdpI/YhfL protein family
NHFGHKIH_00211 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHFGHKIH_00212 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
NHFGHKIH_00213 2.5e-89 M Protein of unknown function (DUF3737)
NHFGHKIH_00215 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHFGHKIH_00216 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
NHFGHKIH_00217 1.6e-21
NHFGHKIH_00218 3.8e-77 comGF U Putative Competence protein ComGF
NHFGHKIH_00219 2.3e-41
NHFGHKIH_00220 1.8e-69
NHFGHKIH_00221 3.1e-43 comGC U competence protein ComGC
NHFGHKIH_00222 1.7e-171 comGB NU type II secretion system
NHFGHKIH_00223 1.7e-179 comGA NU Type II IV secretion system protein
NHFGHKIH_00224 8.9e-133 yebC K Transcriptional regulatory protein
NHFGHKIH_00225 7.6e-94 S VanZ like family
NHFGHKIH_00226 3.5e-101 ylbE GM NAD(P)H-binding
NHFGHKIH_00227 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHFGHKIH_00229 1.3e-160 L hmm pf00665
NHFGHKIH_00230 5.8e-100 L Helix-turn-helix domain
NHFGHKIH_00231 2e-310 E Amino acid permease
NHFGHKIH_00233 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHFGHKIH_00234 2.2e-90 2.7.7.65 T GGDEF domain
NHFGHKIH_00235 8.2e-36
NHFGHKIH_00236 1.5e-111 ica2 GT2 M Glycosyl transferase family group 2
NHFGHKIH_00237 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
NHFGHKIH_00238 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NHFGHKIH_00239 1e-149 D Alpha beta
NHFGHKIH_00240 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHFGHKIH_00241 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHFGHKIH_00242 8.3e-143 licT K CAT RNA binding domain
NHFGHKIH_00243 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NHFGHKIH_00244 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHFGHKIH_00245 1.6e-118
NHFGHKIH_00246 1.8e-75 K Penicillinase repressor
NHFGHKIH_00247 1.4e-147 S hydrolase
NHFGHKIH_00248 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHFGHKIH_00249 2e-172 ybbR S YbbR-like protein
NHFGHKIH_00250 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHFGHKIH_00251 7.3e-208 potD P ABC transporter
NHFGHKIH_00252 4.8e-127 potC P ABC transporter permease
NHFGHKIH_00253 1.3e-129 potB P ABC transporter permease
NHFGHKIH_00254 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHFGHKIH_00255 2e-163 murB 1.3.1.98 M Cell wall formation
NHFGHKIH_00256 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
NHFGHKIH_00257 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NHFGHKIH_00258 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NHFGHKIH_00259 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHFGHKIH_00260 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
NHFGHKIH_00261 1.2e-94
NHFGHKIH_00262 1e-12
NHFGHKIH_00263 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHFGHKIH_00264 1e-205 M Glycosyl hydrolases family 25
NHFGHKIH_00265 1.2e-155 cinI S Serine hydrolase (FSH1)
NHFGHKIH_00266 4.3e-298 S Predicted membrane protein (DUF2207)
NHFGHKIH_00267 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NHFGHKIH_00269 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
NHFGHKIH_00270 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHFGHKIH_00271 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NHFGHKIH_00272 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NHFGHKIH_00273 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NHFGHKIH_00274 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHFGHKIH_00275 3.4e-71 yqhY S Asp23 family, cell envelope-related function
NHFGHKIH_00276 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHFGHKIH_00277 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHFGHKIH_00278 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHFGHKIH_00279 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHFGHKIH_00280 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHFGHKIH_00281 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NHFGHKIH_00282 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
NHFGHKIH_00283 1.1e-77 6.3.3.2 S ASCH
NHFGHKIH_00284 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NHFGHKIH_00285 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHFGHKIH_00286 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHFGHKIH_00288 1.9e-150 L Belongs to the 'phage' integrase family
NHFGHKIH_00289 5e-08 S Pfam:DUF955
NHFGHKIH_00290 1.6e-15 K Helix-turn-helix XRE-family like proteins
NHFGHKIH_00291 1.2e-23 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NHFGHKIH_00292 9.8e-31 K Helix-turn-helix domain
NHFGHKIH_00294 4.1e-09 S Arc-like DNA binding domain
NHFGHKIH_00296 6.6e-21 K Conserved phage C-terminus (Phg_2220_C)
NHFGHKIH_00297 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NHFGHKIH_00298 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NHFGHKIH_00299 9.7e-52 S Iron-sulfur cluster assembly protein
NHFGHKIH_00300 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NHFGHKIH_00301 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NHFGHKIH_00302 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NHFGHKIH_00303 3.4e-278 arlS 2.7.13.3 T Histidine kinase
NHFGHKIH_00304 1.2e-126 K response regulator
NHFGHKIH_00305 4.7e-97 yceD S Uncharacterized ACR, COG1399
NHFGHKIH_00306 1.7e-215 ylbM S Belongs to the UPF0348 family
NHFGHKIH_00307 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHFGHKIH_00308 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NHFGHKIH_00309 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHFGHKIH_00310 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
NHFGHKIH_00311 4.2e-84 yqeG S HAD phosphatase, family IIIA
NHFGHKIH_00312 9.2e-201 tnpB L Putative transposase DNA-binding domain
NHFGHKIH_00313 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHFGHKIH_00314 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHFGHKIH_00315 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NHFGHKIH_00316 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHFGHKIH_00317 4e-98 rihB 3.2.2.1 F Nucleoside
NHFGHKIH_00318 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHFGHKIH_00319 3.3e-275 yjeM E Amino Acid
NHFGHKIH_00320 5.8e-83 S Fic/DOC family
NHFGHKIH_00321 3.1e-278
NHFGHKIH_00322 3.2e-77
NHFGHKIH_00323 2.3e-87 S Protein of unknown function (DUF805)
NHFGHKIH_00324 5.6e-68 O OsmC-like protein
NHFGHKIH_00325 6.7e-207 EGP Major facilitator Superfamily
NHFGHKIH_00326 2.5e-215 sptS 2.7.13.3 T Histidine kinase
NHFGHKIH_00327 1.3e-65 K response regulator
NHFGHKIH_00328 6e-27 K response regulator
NHFGHKIH_00329 7.5e-109 2.7.6.5 T Region found in RelA / SpoT proteins
NHFGHKIH_00330 6.2e-271 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NHFGHKIH_00331 0.0 rafA 3.2.1.22 G alpha-galactosidase
NHFGHKIH_00332 2.8e-210 msmX P Belongs to the ABC transporter superfamily
NHFGHKIH_00333 2e-152 msmG P Binding-protein-dependent transport system inner membrane component
NHFGHKIH_00334 4.8e-157 msmF P Binding-protein-dependent transport system inner membrane component
NHFGHKIH_00335 2.3e-237 msmE G Bacterial extracellular solute-binding protein
NHFGHKIH_00336 1.6e-158 scrR K Periplasmic binding protein domain
NHFGHKIH_00337 5.5e-36
NHFGHKIH_00338 2.2e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NHFGHKIH_00339 3.2e-10 S Domain of unknown function DUF87
NHFGHKIH_00340 1.2e-63 S SIR2-like domain
NHFGHKIH_00341 8.3e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NHFGHKIH_00342 2.3e-51 3.1.21.3 V Type I restriction modification DNA specificity domain
NHFGHKIH_00343 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
NHFGHKIH_00344 3.4e-42 S RloB-like protein
NHFGHKIH_00345 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
NHFGHKIH_00346 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
NHFGHKIH_00347 0.0 S SLAP domain
NHFGHKIH_00349 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
NHFGHKIH_00350 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
NHFGHKIH_00351 3.8e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NHFGHKIH_00352 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NHFGHKIH_00353 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHFGHKIH_00354 2.2e-120 lsa S ABC transporter
NHFGHKIH_00355 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
NHFGHKIH_00356 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
NHFGHKIH_00357 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
NHFGHKIH_00358 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHFGHKIH_00359 2.6e-280 thrC 4.2.3.1 E Threonine synthase
NHFGHKIH_00360 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NHFGHKIH_00361 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHFGHKIH_00362 9.4e-118
NHFGHKIH_00363 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHFGHKIH_00365 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHFGHKIH_00366 1.3e-116 S Peptidase family M23
NHFGHKIH_00367 5.7e-18
NHFGHKIH_00368 1.5e-239 G Bacterial extracellular solute-binding protein
NHFGHKIH_00369 0.0 clpE O Belongs to the ClpA ClpB family
NHFGHKIH_00370 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
NHFGHKIH_00371 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHFGHKIH_00372 1.4e-140 hlyX S Transporter associated domain
NHFGHKIH_00373 2.7e-74
NHFGHKIH_00374 1.6e-85
NHFGHKIH_00375 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
NHFGHKIH_00376 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHFGHKIH_00377 3.7e-122 D Alpha beta
NHFGHKIH_00378 1.8e-38 D Alpha beta
NHFGHKIH_00379 9.4e-46
NHFGHKIH_00380 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHFGHKIH_00381 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHFGHKIH_00382 1.5e-28 secG U Preprotein translocase
NHFGHKIH_00383 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHFGHKIH_00384 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHFGHKIH_00385 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
NHFGHKIH_00386 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NHFGHKIH_00393 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NHFGHKIH_00394 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
NHFGHKIH_00395 5.6e-179 S PFAM Archaeal ATPase
NHFGHKIH_00396 2.4e-73 S cog cog1373
NHFGHKIH_00397 2.6e-61 M Glycosyl hydrolases family 25
NHFGHKIH_00398 1.3e-61 M Glycosyl hydrolases family 25
NHFGHKIH_00399 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
NHFGHKIH_00400 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHFGHKIH_00402 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHFGHKIH_00403 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NHFGHKIH_00404 1.6e-294 L Nuclease-related domain
NHFGHKIH_00405 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHFGHKIH_00406 8.3e-106 S Repeat protein
NHFGHKIH_00407 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NHFGHKIH_00408 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHFGHKIH_00409 5.4e-56 XK27_04120 S Putative amino acid metabolism
NHFGHKIH_00410 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
NHFGHKIH_00411 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHFGHKIH_00412 6.7e-37
NHFGHKIH_00413 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NHFGHKIH_00414 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
NHFGHKIH_00415 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHFGHKIH_00416 2.8e-74 gpsB D DivIVA domain protein
NHFGHKIH_00417 5.7e-149 ylmH S S4 domain protein
NHFGHKIH_00418 1.7e-45 yggT S YGGT family
NHFGHKIH_00419 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHFGHKIH_00420 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHFGHKIH_00421 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHFGHKIH_00422 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHFGHKIH_00423 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHFGHKIH_00424 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHFGHKIH_00425 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHFGHKIH_00426 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NHFGHKIH_00427 1.8e-54 ftsL D Cell division protein FtsL
NHFGHKIH_00428 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHFGHKIH_00429 6.3e-78 mraZ K Belongs to the MraZ family
NHFGHKIH_00430 6.4e-54 S Protein of unknown function (DUF3397)
NHFGHKIH_00432 2.7e-94 mreD
NHFGHKIH_00433 2e-147 mreC M Involved in formation and maintenance of cell shape
NHFGHKIH_00434 2.4e-176 mreB D cell shape determining protein MreB
NHFGHKIH_00435 2.3e-108 radC L DNA repair protein
NHFGHKIH_00436 5.7e-126 S Haloacid dehalogenase-like hydrolase
NHFGHKIH_00437 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHFGHKIH_00438 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHFGHKIH_00439 2.5e-52
NHFGHKIH_00440 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
NHFGHKIH_00441 0.0 3.6.3.8 P P-type ATPase
NHFGHKIH_00443 6.5e-44
NHFGHKIH_00444 1.5e-94 S Protein of unknown function (DUF3990)
NHFGHKIH_00445 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NHFGHKIH_00446 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
NHFGHKIH_00447 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHFGHKIH_00448 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHFGHKIH_00449 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NHFGHKIH_00450 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHFGHKIH_00451 1.1e-212 iscS2 2.8.1.7 E Aminotransferase class V
NHFGHKIH_00452 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHFGHKIH_00453 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHFGHKIH_00454 1.3e-84 yueI S Protein of unknown function (DUF1694)
NHFGHKIH_00455 6.3e-238 rarA L recombination factor protein RarA
NHFGHKIH_00456 8.4e-39
NHFGHKIH_00457 1.8e-78 usp6 T universal stress protein
NHFGHKIH_00458 4.7e-216 rodA D Belongs to the SEDS family
NHFGHKIH_00459 3.3e-33 S Protein of unknown function (DUF2969)
NHFGHKIH_00460 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NHFGHKIH_00461 1.2e-177 mbl D Cell shape determining protein MreB Mrl
NHFGHKIH_00462 2e-30 ywzB S Protein of unknown function (DUF1146)
NHFGHKIH_00463 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NHFGHKIH_00464 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHFGHKIH_00465 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHFGHKIH_00466 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHFGHKIH_00467 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHFGHKIH_00468 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHFGHKIH_00469 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHFGHKIH_00470 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
NHFGHKIH_00471 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHFGHKIH_00472 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHFGHKIH_00473 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHFGHKIH_00474 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHFGHKIH_00475 1.7e-113 tdk 2.7.1.21 F thymidine kinase
NHFGHKIH_00476 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NHFGHKIH_00477 1.5e-203 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHFGHKIH_00478 3.9e-46 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHFGHKIH_00479 1.5e-31 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHFGHKIH_00480 1.2e-225 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHFGHKIH_00481 1.6e-60 clcA P chloride
NHFGHKIH_00482 4.7e-26 K FCD
NHFGHKIH_00483 1.4e-94
NHFGHKIH_00484 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
NHFGHKIH_00485 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NHFGHKIH_00486 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NHFGHKIH_00487 3.5e-71 yqeY S YqeY-like protein
NHFGHKIH_00488 1.2e-174 phoH T phosphate starvation-inducible protein PhoH
NHFGHKIH_00489 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHFGHKIH_00490 8.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHFGHKIH_00491 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
NHFGHKIH_00492 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NHFGHKIH_00493 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NHFGHKIH_00494 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHFGHKIH_00495 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHFGHKIH_00496 1.4e-127 S Peptidase family M23
NHFGHKIH_00497 4.8e-81 mutT 3.6.1.55 F NUDIX domain
NHFGHKIH_00498 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NHFGHKIH_00499 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHFGHKIH_00500 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHFGHKIH_00501 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
NHFGHKIH_00502 9.6e-124 skfE V ATPases associated with a variety of cellular activities
NHFGHKIH_00503 4.5e-141
NHFGHKIH_00504 5.1e-137
NHFGHKIH_00505 6.7e-145
NHFGHKIH_00506 1.4e-26
NHFGHKIH_00507 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NHFGHKIH_00508 7.5e-143
NHFGHKIH_00509 9.7e-169
NHFGHKIH_00510 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NHFGHKIH_00511 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
NHFGHKIH_00512 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHFGHKIH_00513 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NHFGHKIH_00514 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NHFGHKIH_00515 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NHFGHKIH_00516 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NHFGHKIH_00517 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NHFGHKIH_00518 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NHFGHKIH_00519 2.4e-89 ypmB S Protein conserved in bacteria
NHFGHKIH_00520 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NHFGHKIH_00521 1.3e-114 dnaD L DnaD domain protein
NHFGHKIH_00522 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHFGHKIH_00523 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NHFGHKIH_00524 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHFGHKIH_00525 1e-107 ypsA S Belongs to the UPF0398 family
NHFGHKIH_00526 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHFGHKIH_00527 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NHFGHKIH_00528 1e-242 cpdA S Calcineurin-like phosphoesterase
NHFGHKIH_00529 3.4e-79
NHFGHKIH_00530 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
NHFGHKIH_00531 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHFGHKIH_00532 8.2e-85 scrR K Periplasmic binding protein domain
NHFGHKIH_00533 3.6e-39 C FMN_bind
NHFGHKIH_00534 1.5e-81
NHFGHKIH_00535 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NHFGHKIH_00536 2e-85 alkD L DNA alkylation repair enzyme
NHFGHKIH_00537 9.9e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHFGHKIH_00538 6.4e-128 K UTRA domain
NHFGHKIH_00539 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NHFGHKIH_00540 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NHFGHKIH_00541 0.0 L PLD-like domain
NHFGHKIH_00543 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NHFGHKIH_00544 7.5e-103 G Phosphoglycerate mutase family
NHFGHKIH_00545 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NHFGHKIH_00546 2.1e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHFGHKIH_00547 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NHFGHKIH_00548 0.0 lacS G Transporter
NHFGHKIH_00549 3.2e-165 lacR K Transcriptional regulator
NHFGHKIH_00550 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NHFGHKIH_00551 7e-146 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NHFGHKIH_00552 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHFGHKIH_00553 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NHFGHKIH_00554 2e-106 K Transcriptional regulator, AbiEi antitoxin
NHFGHKIH_00555 4.2e-63 lmrB EGP Major facilitator Superfamily
NHFGHKIH_00556 2.9e-122 rbtT P Major Facilitator Superfamily
NHFGHKIH_00557 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
NHFGHKIH_00558 2.5e-86 K GNAT family
NHFGHKIH_00559 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NHFGHKIH_00561 4.3e-36
NHFGHKIH_00562 6.2e-288 P ABC transporter
NHFGHKIH_00563 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHFGHKIH_00564 3.5e-32 ykzG S Belongs to the UPF0356 family
NHFGHKIH_00565 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHFGHKIH_00566 0.0 typA T GTP-binding protein TypA
NHFGHKIH_00567 5.9e-211 ftsW D Belongs to the SEDS family
NHFGHKIH_00568 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NHFGHKIH_00569 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NHFGHKIH_00570 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHFGHKIH_00571 2.4e-187 ylbL T Belongs to the peptidase S16 family
NHFGHKIH_00572 3.1e-79 comEA L Competence protein ComEA
NHFGHKIH_00573 0.0 comEC S Competence protein ComEC
NHFGHKIH_00574 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
NHFGHKIH_00575 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
NHFGHKIH_00576 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHFGHKIH_00577 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHFGHKIH_00578 1.3e-148
NHFGHKIH_00579 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHFGHKIH_00580 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHFGHKIH_00581 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHFGHKIH_00582 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
NHFGHKIH_00583 7.8e-39 yjeM E Amino Acid
NHFGHKIH_00584 3.4e-175 yjeM E Amino Acid
NHFGHKIH_00585 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHFGHKIH_00586 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHFGHKIH_00587 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHFGHKIH_00588 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHFGHKIH_00589 9.8e-55 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHFGHKIH_00590 1.3e-153 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHFGHKIH_00591 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHFGHKIH_00592 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHFGHKIH_00593 1e-215 aspC 2.6.1.1 E Aminotransferase
NHFGHKIH_00594 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHFGHKIH_00595 2.1e-194 pbpX1 V Beta-lactamase
NHFGHKIH_00596 1.2e-299 I Protein of unknown function (DUF2974)
NHFGHKIH_00597 1.5e-102 GM NmrA-like family
NHFGHKIH_00598 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHFGHKIH_00599 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHFGHKIH_00600 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHFGHKIH_00601 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHFGHKIH_00602 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NHFGHKIH_00603 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHFGHKIH_00604 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHFGHKIH_00605 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NHFGHKIH_00606 3.7e-250 lctP C L-lactate permease
NHFGHKIH_00607 3.1e-148 glcU U sugar transport
NHFGHKIH_00608 7.1e-46
NHFGHKIH_00609 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NHFGHKIH_00610 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHFGHKIH_00611 1e-23 S Alpha beta hydrolase
NHFGHKIH_00612 1.2e-63 S Alpha beta hydrolase
NHFGHKIH_00613 1.9e-37
NHFGHKIH_00614 7e-50
NHFGHKIH_00615 1.7e-148 S haloacid dehalogenase-like hydrolase
NHFGHKIH_00616 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
NHFGHKIH_00617 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
NHFGHKIH_00618 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
NHFGHKIH_00619 8.5e-178 I Carboxylesterase family
NHFGHKIH_00621 2.2e-111 L Belongs to the 'phage' integrase family
NHFGHKIH_00622 5e-08 S Pfam:DUF955
NHFGHKIH_00623 3.4e-29 K Helix-turn-helix XRE-family like proteins
NHFGHKIH_00624 5.7e-16 K Helix-turn-helix XRE-family like proteins
NHFGHKIH_00625 2e-32 K Helix-turn-helix domain
NHFGHKIH_00626 1.7e-25 S Domain of unknown function (DUF771)
NHFGHKIH_00633 7e-87 gtcA S Teichoic acid glycosylation protein
NHFGHKIH_00634 4.1e-80 fld C Flavodoxin
NHFGHKIH_00635 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
NHFGHKIH_00636 3.6e-163 yihY S Belongs to the UPF0761 family
NHFGHKIH_00637 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHFGHKIH_00638 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
NHFGHKIH_00639 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NHFGHKIH_00640 3.7e-102 L Integrase
NHFGHKIH_00641 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
NHFGHKIH_00642 1.3e-30
NHFGHKIH_00643 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHFGHKIH_00645 2e-178 MA20_14895 S Conserved hypothetical protein 698
NHFGHKIH_00646 1.1e-83 dps P Belongs to the Dps family
NHFGHKIH_00647 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
NHFGHKIH_00648 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NHFGHKIH_00649 1.8e-58 S Putative adhesin
NHFGHKIH_00650 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
NHFGHKIH_00651 2e-234 mepA V MATE efflux family protein
NHFGHKIH_00652 4.2e-92 S SNARE associated Golgi protein
NHFGHKIH_00653 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NHFGHKIH_00654 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHFGHKIH_00655 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHFGHKIH_00656 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
NHFGHKIH_00657 6.8e-110 yjbK S CYTH
NHFGHKIH_00658 4.6e-114 yjbH Q Thioredoxin
NHFGHKIH_00659 1.4e-158 coiA 3.6.4.12 S Competence protein
NHFGHKIH_00660 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHFGHKIH_00661 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHFGHKIH_00662 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHFGHKIH_00663 8.5e-41 ptsH G phosphocarrier protein HPR
NHFGHKIH_00664 5.3e-26
NHFGHKIH_00665 9.9e-82 C Flavodoxin
NHFGHKIH_00666 0.0 uvrA3 L excinuclease ABC, A subunit
NHFGHKIH_00667 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NHFGHKIH_00668 2.1e-114 3.6.1.27 I Acid phosphatase homologues
NHFGHKIH_00669 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
NHFGHKIH_00670 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHFGHKIH_00671 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
NHFGHKIH_00672 9.3e-204 pbpX1 V Beta-lactamase
NHFGHKIH_00673 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NHFGHKIH_00674 7.5e-95 S ECF-type riboflavin transporter, S component
NHFGHKIH_00675 3.4e-126 1.3.5.4 C FAD binding domain
NHFGHKIH_00676 1.7e-213 1.3.5.4 C FAD binding domain
NHFGHKIH_00677 1.2e-210 S Bacterial protein of unknown function (DUF871)
NHFGHKIH_00678 2.3e-43 ybhL S Belongs to the BI1 family
NHFGHKIH_00679 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NHFGHKIH_00680 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NHFGHKIH_00681 2.6e-214 yubA S AI-2E family transporter
NHFGHKIH_00682 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHFGHKIH_00683 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
NHFGHKIH_00684 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NHFGHKIH_00685 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NHFGHKIH_00686 1.9e-236 S Peptidase M16
NHFGHKIH_00687 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
NHFGHKIH_00688 5.2e-97 ymfM S Helix-turn-helix domain
NHFGHKIH_00689 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHFGHKIH_00690 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHFGHKIH_00691 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
NHFGHKIH_00692 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
NHFGHKIH_00693 5.1e-119 yvyE 3.4.13.9 S YigZ family
NHFGHKIH_00694 4.7e-246 comFA L Helicase C-terminal domain protein
NHFGHKIH_00695 9.4e-132 comFC S Competence protein
NHFGHKIH_00696 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHFGHKIH_00697 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHFGHKIH_00698 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHFGHKIH_00699 5.1e-17
NHFGHKIH_00700 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHFGHKIH_00701 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHFGHKIH_00702 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NHFGHKIH_00703 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHFGHKIH_00704 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NHFGHKIH_00705 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHFGHKIH_00706 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHFGHKIH_00707 4.1e-90 S Short repeat of unknown function (DUF308)
NHFGHKIH_00708 2.4e-164 rapZ S Displays ATPase and GTPase activities
NHFGHKIH_00709 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NHFGHKIH_00710 2.1e-171 whiA K May be required for sporulation
NHFGHKIH_00711 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHFGHKIH_00712 0.0 S SH3-like domain
NHFGHKIH_00713 4.9e-111 ybbL S ABC transporter, ATP-binding protein
NHFGHKIH_00714 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
NHFGHKIH_00715 3.7e-131 gmuR K UTRA
NHFGHKIH_00716 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHFGHKIH_00717 3.5e-70 S Domain of unknown function (DUF3284)
NHFGHKIH_00718 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHFGHKIH_00719 2.6e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NHFGHKIH_00720 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NHFGHKIH_00721 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHFGHKIH_00723 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHFGHKIH_00724 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHFGHKIH_00725 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NHFGHKIH_00726 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NHFGHKIH_00727 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NHFGHKIH_00728 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHFGHKIH_00729 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHFGHKIH_00730 2.3e-56 G Xylose isomerase domain protein TIM barrel
NHFGHKIH_00731 8.4e-90 nanK GK ROK family
NHFGHKIH_00732 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NHFGHKIH_00733 3.7e-66 K Helix-turn-helix domain, rpiR family
NHFGHKIH_00734 7.1e-263 E ABC transporter, substratebinding protein
NHFGHKIH_00735 9.1e-10 K peptidyl-tyrosine sulfation
NHFGHKIH_00737 1.2e-128 S interspecies interaction between organisms
NHFGHKIH_00738 2.7e-34
NHFGHKIH_00741 1.9e-21
NHFGHKIH_00742 6e-148
NHFGHKIH_00743 6.7e-170
NHFGHKIH_00744 2e-263 glnA 6.3.1.2 E glutamine synthetase
NHFGHKIH_00745 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
NHFGHKIH_00746 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHFGHKIH_00747 1.5e-65 yqhL P Rhodanese-like protein
NHFGHKIH_00748 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NHFGHKIH_00749 4e-119 gluP 3.4.21.105 S Rhomboid family
NHFGHKIH_00750 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHFGHKIH_00751 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHFGHKIH_00752 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NHFGHKIH_00753 0.0 S membrane
NHFGHKIH_00754 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NHFGHKIH_00755 1.3e-38 S RelB antitoxin
NHFGHKIH_00756 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NHFGHKIH_00757 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHFGHKIH_00758 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
NHFGHKIH_00759 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHFGHKIH_00760 8.7e-159 isdE P Periplasmic binding protein
NHFGHKIH_00761 6.3e-123 M Iron Transport-associated domain
NHFGHKIH_00762 3e-09 isdH M Iron Transport-associated domain
NHFGHKIH_00763 2.2e-89
NHFGHKIH_00768 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHFGHKIH_00769 5.4e-122 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHFGHKIH_00770 5.8e-211 M Glycosyl hydrolases family 25
NHFGHKIH_00771 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
NHFGHKIH_00772 4.1e-67
NHFGHKIH_00773 5.4e-203 xerS L Belongs to the 'phage' integrase family
NHFGHKIH_00774 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHFGHKIH_00775 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NHFGHKIH_00776 3.2e-181 ccpA K catabolite control protein A
NHFGHKIH_00777 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHFGHKIH_00778 4.3e-55
NHFGHKIH_00779 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NHFGHKIH_00780 2.1e-92 yutD S Protein of unknown function (DUF1027)
NHFGHKIH_00781 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHFGHKIH_00782 3.7e-100 S Protein of unknown function (DUF1461)
NHFGHKIH_00783 6.8e-116 dedA S SNARE-like domain protein
NHFGHKIH_00784 2.8e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NHFGHKIH_00785 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NHFGHKIH_00786 9e-98
NHFGHKIH_00787 5.9e-106 K LysR substrate binding domain
NHFGHKIH_00788 1e-20
NHFGHKIH_00789 2.3e-215 S Sterol carrier protein domain
NHFGHKIH_00790 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NHFGHKIH_00791 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
NHFGHKIH_00792 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHFGHKIH_00793 5.7e-233 arcA 3.5.3.6 E Arginine
NHFGHKIH_00794 9e-137 lysR5 K LysR substrate binding domain
NHFGHKIH_00795 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NHFGHKIH_00796 1e-48 S Metal binding domain of Ada
NHFGHKIH_00797 3.8e-44 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHFGHKIH_00798 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHFGHKIH_00799 1.1e-138 stp 3.1.3.16 T phosphatase
NHFGHKIH_00800 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NHFGHKIH_00801 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHFGHKIH_00802 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NHFGHKIH_00803 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
NHFGHKIH_00804 1.4e-30
NHFGHKIH_00805 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NHFGHKIH_00806 4e-57 asp S Asp23 family, cell envelope-related function
NHFGHKIH_00807 7.6e-305 yloV S DAK2 domain fusion protein YloV
NHFGHKIH_00808 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHFGHKIH_00809 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHFGHKIH_00810 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHFGHKIH_00811 1.1e-192 oppD P Belongs to the ABC transporter superfamily
NHFGHKIH_00812 1.5e-170 oppF P Belongs to the ABC transporter superfamily
NHFGHKIH_00813 2.6e-172 oppB P ABC transporter permease
NHFGHKIH_00814 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
NHFGHKIH_00815 9.7e-46 oppA E ABC transporter substrate-binding protein
NHFGHKIH_00816 0.0 dnaE 2.7.7.7 L DNA polymerase
NHFGHKIH_00817 2.3e-23 S Protein of unknown function (DUF2929)
NHFGHKIH_00818 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NHFGHKIH_00819 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NHFGHKIH_00820 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
NHFGHKIH_00821 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHFGHKIH_00822 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHFGHKIH_00823 2.2e-292 I Acyltransferase
NHFGHKIH_00824 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHFGHKIH_00825 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHFGHKIH_00826 4.4e-109 dedA 3.1.3.1 S SNARE associated Golgi protein
NHFGHKIH_00827 1.1e-243 yfnA E Amino Acid
NHFGHKIH_00828 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHFGHKIH_00829 1.3e-148 yxeH S hydrolase
NHFGHKIH_00830 2.7e-32 S reductase
NHFGHKIH_00831 4.4e-39 S reductase
NHFGHKIH_00832 4.8e-34 S reductase
NHFGHKIH_00833 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHFGHKIH_00834 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
NHFGHKIH_00835 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
NHFGHKIH_00836 3.6e-74 3.6.3.6 P Cation transporter/ATPase, N-terminus
NHFGHKIH_00837 2.4e-158 3.6.3.6 P Cation transporter/ATPase, N-terminus
NHFGHKIH_00838 1.9e-19
NHFGHKIH_00839 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NHFGHKIH_00840 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHFGHKIH_00841 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NHFGHKIH_00842 1e-167 cvfB S S1 domain
NHFGHKIH_00843 2.9e-165 xerD D recombinase XerD
NHFGHKIH_00844 8.1e-54 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHFGHKIH_00845 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHFGHKIH_00846 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHFGHKIH_00847 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHFGHKIH_00848 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHFGHKIH_00849 2.7e-18 M Lysin motif
NHFGHKIH_00850 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NHFGHKIH_00851 1.4e-24 rpsA 1.17.7.4 J Ribosomal protein S1
NHFGHKIH_00852 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NHFGHKIH_00853 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHFGHKIH_00854 1.4e-75 S Tetratricopeptide repeat protein
NHFGHKIH_00855 3.8e-99 S Tetratricopeptide repeat protein
NHFGHKIH_00856 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHFGHKIH_00857 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NHFGHKIH_00858 1.2e-100 treR K UTRA
NHFGHKIH_00859 4.5e-111 treB G phosphotransferase system
NHFGHKIH_00860 6.8e-153 treB G phosphotransferase system
NHFGHKIH_00861 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHFGHKIH_00862 1.9e-191 yrvN L AAA C-terminal domain
NHFGHKIH_00863 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHFGHKIH_00864 9e-83 K Acetyltransferase (GNAT) domain
NHFGHKIH_00865 1.3e-229 S Putative peptidoglycan binding domain
NHFGHKIH_00867 2.6e-26 S Domain of unknown function (DUF771)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)