ORF_ID e_value Gene_name EC_number CAZy COGs Description
BLMMEKKC_00001 6e-160 rapZ S Displays ATPase and GTPase activities
BLMMEKKC_00002 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
BLMMEKKC_00003 6.2e-171 whiA K May be required for sporulation
BLMMEKKC_00004 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BLMMEKKC_00005 1.2e-277 ycaM E amino acid
BLMMEKKC_00007 2.3e-187 cggR K Putative sugar-binding domain
BLMMEKKC_00008 1.6e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BLMMEKKC_00009 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
BLMMEKKC_00010 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BLMMEKKC_00011 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BLMMEKKC_00012 2.5e-28 secG U Preprotein translocase
BLMMEKKC_00013 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BLMMEKKC_00014 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BLMMEKKC_00015 2.9e-107 3.2.2.20 K acetyltransferase
BLMMEKKC_00017 6.6e-91
BLMMEKKC_00018 2.9e-93
BLMMEKKC_00019 8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
BLMMEKKC_00020 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BLMMEKKC_00021 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
BLMMEKKC_00022 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
BLMMEKKC_00023 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
BLMMEKKC_00024 4.4e-166 murB 1.3.1.98 M Cell wall formation
BLMMEKKC_00025 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BLMMEKKC_00026 2.7e-130 potB P ABC transporter permease
BLMMEKKC_00027 8.5e-137 potC P ABC transporter permease
BLMMEKKC_00028 1.3e-209 potD P ABC transporter
BLMMEKKC_00029 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BLMMEKKC_00030 8.1e-174 ybbR S YbbR-like protein
BLMMEKKC_00031 2.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLMMEKKC_00032 3.8e-148 S Sucrose-6F-phosphate phosphohydrolase
BLMMEKKC_00033 2.3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLMMEKKC_00034 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLMMEKKC_00035 3.1e-178 S Putative adhesin
BLMMEKKC_00036 4.8e-115
BLMMEKKC_00037 8.5e-150 yisY 1.11.1.10 S Alpha/beta hydrolase family
BLMMEKKC_00038 4.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
BLMMEKKC_00039 3.7e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLMMEKKC_00040 7.3e-97 S VanZ like family
BLMMEKKC_00041 1.5e-132 yebC K Transcriptional regulatory protein
BLMMEKKC_00042 5.8e-180 comGA NU Type II IV secretion system protein
BLMMEKKC_00043 4.7e-177 comGB NU type II secretion system
BLMMEKKC_00044 1.1e-36 comGC U Required for transformation and DNA binding
BLMMEKKC_00045 3.7e-67
BLMMEKKC_00046 3.9e-08
BLMMEKKC_00047 4.7e-88 comGF U Putative Competence protein ComGF
BLMMEKKC_00048 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
BLMMEKKC_00049 1.1e-231 S Tetratricopeptide repeat protein
BLMMEKKC_00050 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BLMMEKKC_00051 9.4e-242 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
BLMMEKKC_00052 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
BLMMEKKC_00053 1.4e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
BLMMEKKC_00054 3.8e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BLMMEKKC_00055 1.9e-58 M Lysin motif
BLMMEKKC_00056 1.8e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BLMMEKKC_00057 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BLMMEKKC_00058 1.1e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BLMMEKKC_00059 3.1e-62 ribT K acetyltransferase
BLMMEKKC_00060 2.5e-169 xerD D recombinase XerD
BLMMEKKC_00061 1.5e-166 cvfB S S1 domain
BLMMEKKC_00062 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
BLMMEKKC_00063 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BLMMEKKC_00065 0.0 dnaE 2.7.7.7 L DNA polymerase
BLMMEKKC_00066 2.1e-28 S Protein of unknown function (DUF2929)
BLMMEKKC_00067 9e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BLMMEKKC_00068 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
BLMMEKKC_00069 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
BLMMEKKC_00070 9.3e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BLMMEKKC_00071 1.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BLMMEKKC_00072 0.0 oatA I Acyltransferase
BLMMEKKC_00073 3.9e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BLMMEKKC_00074 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BLMMEKKC_00075 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
BLMMEKKC_00076 1.9e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
BLMMEKKC_00077 5.1e-116 GM NmrA-like family
BLMMEKKC_00078 7.7e-247 yagE E amino acid
BLMMEKKC_00079 7.4e-88 S Rib/alpha-like repeat
BLMMEKKC_00080 1.6e-64 S Domain of unknown function DUF1828
BLMMEKKC_00081 7.2e-68
BLMMEKKC_00082 2.1e-48 M domain protein
BLMMEKKC_00083 2.4e-301
BLMMEKKC_00084 1.8e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
BLMMEKKC_00085 3.9e-113 3.6.1.55 F NUDIX domain
BLMMEKKC_00086 5.8e-63 S Putative adhesin
BLMMEKKC_00087 9.2e-248 brnQ U Component of the transport system for branched-chain amino acids
BLMMEKKC_00088 1.4e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BLMMEKKC_00089 2.9e-70 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BLMMEKKC_00090 4.5e-17 L Plasmid pRiA4b ORF-3-like protein
BLMMEKKC_00091 5.2e-68 K HxlR family
BLMMEKKC_00092 2.7e-48
BLMMEKKC_00093 5.1e-231 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
BLMMEKKC_00094 2.5e-11 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
BLMMEKKC_00095 3e-76 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
BLMMEKKC_00096 3.2e-292 P ABC transporter
BLMMEKKC_00097 5e-235 V ABC-type multidrug transport system, ATPase and permease components
BLMMEKKC_00098 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BLMMEKKC_00099 0.0 S membrane
BLMMEKKC_00100 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
BLMMEKKC_00101 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BLMMEKKC_00102 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BLMMEKKC_00103 4.5e-118 gluP 3.4.21.105 S Rhomboid family
BLMMEKKC_00104 6e-35 yqgQ S Bacterial protein of unknown function (DUF910)
BLMMEKKC_00105 1.5e-57 yqhL P Rhodanese-like protein
BLMMEKKC_00106 1.1e-18 S Protein of unknown function (DUF3042)
BLMMEKKC_00107 9.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BLMMEKKC_00108 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
BLMMEKKC_00109 2.8e-205 EGP Major facilitator Superfamily
BLMMEKKC_00110 4.3e-152 S haloacid dehalogenase-like hydrolase
BLMMEKKC_00111 2.4e-07
BLMMEKKC_00112 8.1e-179 D Alpha beta
BLMMEKKC_00113 6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
BLMMEKKC_00114 3.9e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
BLMMEKKC_00115 2.9e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
BLMMEKKC_00116 9.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLMMEKKC_00117 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
BLMMEKKC_00118 2.4e-112 ygaC J Belongs to the UPF0374 family
BLMMEKKC_00119 4.9e-90
BLMMEKKC_00120 3e-78
BLMMEKKC_00121 1.6e-157 hlyX S Transporter associated domain
BLMMEKKC_00122 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BLMMEKKC_00123 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
BLMMEKKC_00124 0.0 clpE O Belongs to the ClpA ClpB family
BLMMEKKC_00125 6.9e-26
BLMMEKKC_00126 1.2e-39 ptsH G phosphocarrier protein HPR
BLMMEKKC_00127 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BLMMEKKC_00128 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BLMMEKKC_00129 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BLMMEKKC_00130 1.7e-162 coiA 3.6.4.12 S Competence protein
BLMMEKKC_00131 7e-107 yjbH Q Thioredoxin
BLMMEKKC_00132 3.3e-112 yjbK S CYTH
BLMMEKKC_00133 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
BLMMEKKC_00134 5.2e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLMMEKKC_00135 3.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BLMMEKKC_00136 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
BLMMEKKC_00137 3.9e-234 N Uncharacterized conserved protein (DUF2075)
BLMMEKKC_00138 4.8e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
BLMMEKKC_00139 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
BLMMEKKC_00140 5.4e-212 yubA S AI-2E family transporter
BLMMEKKC_00141 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BLMMEKKC_00142 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
BLMMEKKC_00143 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
BLMMEKKC_00144 2.9e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLMMEKKC_00145 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BLMMEKKC_00146 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BLMMEKKC_00147 7.3e-64 yodB K Transcriptional regulator, HxlR family
BLMMEKKC_00148 9.6e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLMMEKKC_00149 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
BLMMEKKC_00150 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BLMMEKKC_00151 1.9e-281 arlS 2.7.13.3 T Histidine kinase
BLMMEKKC_00152 1.1e-130 K response regulator
BLMMEKKC_00153 2.9e-96 yceD S Uncharacterized ACR, COG1399
BLMMEKKC_00154 2.2e-218 ylbM S Belongs to the UPF0348 family
BLMMEKKC_00155 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BLMMEKKC_00156 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
BLMMEKKC_00157 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLMMEKKC_00158 4.7e-210 yqeH S Ribosome biogenesis GTPase YqeH
BLMMEKKC_00159 3.5e-91 yqeG S HAD phosphatase, family IIIA
BLMMEKKC_00160 9.8e-191 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BLMMEKKC_00161 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BLMMEKKC_00162 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
BLMMEKKC_00163 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLMMEKKC_00164 5e-60
BLMMEKKC_00176 1.2e-216 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
BLMMEKKC_00177 3.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
BLMMEKKC_00178 4.5e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BLMMEKKC_00179 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
BLMMEKKC_00180 4.2e-106 ypsA S Belongs to the UPF0398 family
BLMMEKKC_00181 1.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BLMMEKKC_00182 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
BLMMEKKC_00183 1.2e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BLMMEKKC_00184 6.7e-116 dnaD L DnaD domain protein
BLMMEKKC_00185 2.9e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
BLMMEKKC_00186 4.8e-90 ypmB S Protein conserved in bacteria
BLMMEKKC_00187 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
BLMMEKKC_00188 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
BLMMEKKC_00189 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
BLMMEKKC_00190 1.3e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
BLMMEKKC_00191 3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
BLMMEKKC_00192 2.7e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
BLMMEKKC_00193 5.2e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BLMMEKKC_00194 1.6e-272 V ABC-type multidrug transport system, ATPase and permease components
BLMMEKKC_00195 1.8e-287 V ABC-type multidrug transport system, ATPase and permease components
BLMMEKKC_00196 1.2e-22 K Acetyltransferase (GNAT) domain
BLMMEKKC_00197 4.5e-36 K Acetyltransferase (GNAT) domain
BLMMEKKC_00198 1.1e-48
BLMMEKKC_00199 5e-282 V ABC transporter transmembrane region
BLMMEKKC_00200 1.7e-84 C nitroreductase
BLMMEKKC_00201 2e-294 V ABC-type multidrug transport system, ATPase and permease components
BLMMEKKC_00202 2.6e-149 ropB K Helix-turn-helix domain
BLMMEKKC_00203 1.6e-128 qmcA O prohibitin homologues
BLMMEKKC_00204 1.2e-141 S Protein of unknown function (DUF975)
BLMMEKKC_00205 1.3e-54 K sequence-specific DNA binding
BLMMEKKC_00206 1e-09 K sequence-specific DNA binding
BLMMEKKC_00207 2e-105 speG J Acetyltransferase (GNAT) domain
BLMMEKKC_00208 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BLMMEKKC_00209 0.0 typA T GTP-binding protein TypA
BLMMEKKC_00210 2.5e-209 ftsW D Belongs to the SEDS family
BLMMEKKC_00211 7.9e-52 ylbG S UPF0298 protein
BLMMEKKC_00212 1.6e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
BLMMEKKC_00213 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BLMMEKKC_00214 2.5e-186 ylbL T Belongs to the peptidase S16 family
BLMMEKKC_00215 2.4e-79 comEA L Competence protein ComEA
BLMMEKKC_00216 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
BLMMEKKC_00217 3.3e-124 skfE V ATPases associated with a variety of cellular activities
BLMMEKKC_00218 2.1e-138
BLMMEKKC_00219 2.3e-108
BLMMEKKC_00220 8.1e-22
BLMMEKKC_00221 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BLMMEKKC_00222 4e-133
BLMMEKKC_00223 1.1e-167
BLMMEKKC_00224 1.5e-229 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
BLMMEKKC_00225 3.5e-52 ybjQ S Belongs to the UPF0145 family
BLMMEKKC_00226 1.7e-161 XK27_05540 S DUF218 domain
BLMMEKKC_00227 5.1e-153 yxeH S hydrolase
BLMMEKKC_00228 2.3e-303 I Protein of unknown function (DUF2974)
BLMMEKKC_00229 2.7e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BLMMEKKC_00230 1.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BLMMEKKC_00231 6.8e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BLMMEKKC_00232 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BLMMEKKC_00233 2.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
BLMMEKKC_00234 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BLMMEKKC_00235 1.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
BLMMEKKC_00236 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
BLMMEKKC_00237 3.3e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BLMMEKKC_00238 3.6e-27 pncA Q Isochorismatase family
BLMMEKKC_00239 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BLMMEKKC_00240 5.7e-126 alkD L DNA alkylation repair enzyme
BLMMEKKC_00242 2.9e-128 XK27_06785 V ABC transporter, ATP-binding protein
BLMMEKKC_00243 0.0 XK27_06780 V ABC transporter permease
BLMMEKKC_00244 0.0 pepO 3.4.24.71 O Peptidase family M13
BLMMEKKC_00245 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
BLMMEKKC_00246 2.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BLMMEKKC_00247 9.5e-283 thrC 4.2.3.1 E Threonine synthase
BLMMEKKC_00248 2.7e-230 hom1 1.1.1.3 E homoserine dehydrogenase
BLMMEKKC_00249 3.3e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BLMMEKKC_00250 1.1e-167 lysR7 K LysR substrate binding domain
BLMMEKKC_00251 0.0 1.3.5.4 C FMN_bind
BLMMEKKC_00252 8.4e-119 drgA C nitroreductase
BLMMEKKC_00253 2.8e-28
BLMMEKKC_00254 8.4e-50
BLMMEKKC_00255 2e-42 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
BLMMEKKC_00256 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
BLMMEKKC_00257 2.8e-96
BLMMEKKC_00258 1.2e-64
BLMMEKKC_00259 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
BLMMEKKC_00260 5.3e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BLMMEKKC_00261 6.4e-105 S Iron-sulfur cluster assembly protein
BLMMEKKC_00262 1.4e-228 XK27_04775 S PAS domain
BLMMEKKC_00264 2.2e-102 3.6.1.27 I Acid phosphatase homologues
BLMMEKKC_00265 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BLMMEKKC_00266 3.7e-18 S Sugar efflux transporter for intercellular exchange
BLMMEKKC_00267 7.6e-310 ybiT S ABC transporter, ATP-binding protein
BLMMEKKC_00268 1e-40 K Helix-turn-helix domain
BLMMEKKC_00269 2.8e-146 F DNA/RNA non-specific endonuclease
BLMMEKKC_00270 7.6e-60 L nuclease
BLMMEKKC_00271 1.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
BLMMEKKC_00272 1.6e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLMMEKKC_00273 2.8e-67 metI P ABC transporter permease
BLMMEKKC_00274 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
BLMMEKKC_00275 2.1e-260 frdC 1.3.5.4 C FAD binding domain
BLMMEKKC_00276 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BLMMEKKC_00277 2.2e-257 yjjP S Putative threonine/serine exporter
BLMMEKKC_00278 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
BLMMEKKC_00279 0.0 aha1 P E1-E2 ATPase
BLMMEKKC_00280 0.0 S Bacterial membrane protein, YfhO
BLMMEKKC_00281 3e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BLMMEKKC_00282 4.6e-174 prmA J Ribosomal protein L11 methyltransferase
BLMMEKKC_00283 1.4e-65
BLMMEKKC_00284 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BLMMEKKC_00285 7.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BLMMEKKC_00286 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
BLMMEKKC_00287 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BLMMEKKC_00288 3.1e-73
BLMMEKKC_00289 1.5e-82 mutT 3.6.1.55 F NUDIX domain
BLMMEKKC_00290 5.8e-35
BLMMEKKC_00291 6.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
BLMMEKKC_00292 4.8e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BLMMEKKC_00293 4.1e-130 ymfC K UTRA
BLMMEKKC_00294 8.2e-254 3.5.1.18 E Peptidase family M20/M25/M40
BLMMEKKC_00295 3.3e-180 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
BLMMEKKC_00296 2.9e-93 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
BLMMEKKC_00297 2.4e-197 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BLMMEKKC_00298 1.2e-117 cutC P Participates in the control of copper homeostasis
BLMMEKKC_00299 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
BLMMEKKC_00300 1.4e-75 K UTRA
BLMMEKKC_00301 5.9e-12
BLMMEKKC_00302 4e-69 rmaI K Transcriptional regulator
BLMMEKKC_00303 1.4e-211 EGP Major facilitator Superfamily
BLMMEKKC_00304 5.7e-230 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
BLMMEKKC_00305 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLMMEKKC_00306 1.1e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BLMMEKKC_00307 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLMMEKKC_00308 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLMMEKKC_00309 2.3e-251 dnaB L Replication initiation and membrane attachment
BLMMEKKC_00310 2.7e-163 dnaI L Primosomal protein DnaI
BLMMEKKC_00311 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLMMEKKC_00312 1.4e-72 K LytTr DNA-binding domain
BLMMEKKC_00313 1.9e-74 S Protein of unknown function (DUF3021)
BLMMEKKC_00314 4.8e-171 V ABC transporter
BLMMEKKC_00315 1.3e-131 S domain protein
BLMMEKKC_00316 9.5e-119 ybhL S Belongs to the BI1 family
BLMMEKKC_00317 2.3e-105 4.1.1.45 S Amidohydrolase
BLMMEKKC_00318 1.5e-33 4.1.1.45 S Amidohydrolase
BLMMEKKC_00319 6.8e-245 yrvN L AAA C-terminal domain
BLMMEKKC_00320 7.3e-58 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
BLMMEKKC_00321 1.3e-53 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
BLMMEKKC_00322 2.5e-86 XK27_09675 K Acetyltransferase (GNAT) domain
BLMMEKKC_00323 7.9e-69 ogt 2.1.1.63 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
BLMMEKKC_00324 8.8e-75 K Transcriptional regulator
BLMMEKKC_00325 5.5e-50 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
BLMMEKKC_00326 6.9e-80 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
BLMMEKKC_00327 2.1e-96 K Acetyltransferase (GNAT) family
BLMMEKKC_00328 1.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
BLMMEKKC_00329 1.4e-93 dps P Belongs to the Dps family
BLMMEKKC_00330 4.6e-35 copZ C Heavy-metal-associated domain
BLMMEKKC_00331 8.4e-242 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
BLMMEKKC_00332 5.5e-50 K LytTr DNA-binding domain
BLMMEKKC_00333 1.3e-21 cylB V ABC-2 type transporter
BLMMEKKC_00334 2.4e-68 S pyridoxamine 5-phosphate
BLMMEKKC_00335 2.9e-78 yobV1 K WYL domain
BLMMEKKC_00336 1.3e-70 yobV1 K WYL domain
BLMMEKKC_00337 4.1e-30 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
BLMMEKKC_00338 2.3e-63 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
BLMMEKKC_00339 4.1e-264 npr 1.11.1.1 C NADH oxidase
BLMMEKKC_00340 1.9e-32 G Major facilitator Superfamily
BLMMEKKC_00341 4.9e-61 S Sulfite exporter TauE/SafE
BLMMEKKC_00342 1.9e-119 mdt(A) EGP Major facilitator Superfamily
BLMMEKKC_00343 7.2e-88 mdt(A) EGP Major facilitator Superfamily
BLMMEKKC_00344 2.1e-117 GM NAD(P)H-binding
BLMMEKKC_00345 1.7e-231 E Alpha/beta hydrolase of unknown function (DUF1100)
BLMMEKKC_00346 9.2e-101 K Transcriptional regulator C-terminal region
BLMMEKKC_00348 3.8e-156 C Aldo keto reductase
BLMMEKKC_00349 3.9e-126 lmrA 3.6.3.44 V ABC transporter
BLMMEKKC_00350 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
BLMMEKKC_00351 1.7e-32 mta K helix_turn_helix, mercury resistance
BLMMEKKC_00352 4.4e-35 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
BLMMEKKC_00353 3.1e-189 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
BLMMEKKC_00354 1.2e-50 yphH S Cupin domain
BLMMEKKC_00355 1.4e-158 lysR5 K LysR substrate binding domain
BLMMEKKC_00356 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
BLMMEKKC_00357 3e-251 G Major Facilitator
BLMMEKKC_00358 1.6e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BLMMEKKC_00359 9.4e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BLMMEKKC_00360 9.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLMMEKKC_00361 1.1e-278 yjeM E Amino Acid
BLMMEKKC_00362 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLMMEKKC_00363 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
BLMMEKKC_00364 9.3e-124 srtA 3.4.22.70 M sortase family
BLMMEKKC_00365 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BLMMEKKC_00366 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BLMMEKKC_00367 0.0 dnaK O Heat shock 70 kDa protein
BLMMEKKC_00368 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BLMMEKKC_00369 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BLMMEKKC_00370 6.7e-121 S GyrI-like small molecule binding domain
BLMMEKKC_00371 1.6e-282 lsa S ABC transporter
BLMMEKKC_00372 7.6e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
BLMMEKKC_00373 5.2e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BLMMEKKC_00374 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BLMMEKKC_00375 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLMMEKKC_00376 6e-46 rplGA J ribosomal protein
BLMMEKKC_00377 2e-46 ylxR K Protein of unknown function (DUF448)
BLMMEKKC_00378 1.1e-217 nusA K Participates in both transcription termination and antitermination
BLMMEKKC_00379 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
BLMMEKKC_00380 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLMMEKKC_00381 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BLMMEKKC_00382 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
BLMMEKKC_00383 1.1e-136 cdsA 2.7.7.41 S Belongs to the CDS family
BLMMEKKC_00384 5.5e-135 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BLMMEKKC_00385 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BLMMEKKC_00386 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
BLMMEKKC_00387 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BLMMEKKC_00388 2.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
BLMMEKKC_00389 1e-43 S Short repeat of unknown function (DUF308)
BLMMEKKC_00390 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
BLMMEKKC_00391 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BLMMEKKC_00392 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
BLMMEKKC_00393 1.6e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
BLMMEKKC_00394 5.2e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
BLMMEKKC_00395 1.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BLMMEKKC_00396 9.2e-181 lacR K Transcriptional regulator
BLMMEKKC_00397 1.4e-122 KL domain protein
BLMMEKKC_00398 3.5e-307 KL domain protein
BLMMEKKC_00399 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
BLMMEKKC_00400 2.8e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
BLMMEKKC_00401 1.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BLMMEKKC_00402 2.3e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BLMMEKKC_00403 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
BLMMEKKC_00404 9.9e-58
BLMMEKKC_00405 2.2e-173 degV S DegV family
BLMMEKKC_00406 1.6e-221 cpdA S Calcineurin-like phosphoesterase
BLMMEKKC_00407 2.4e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
BLMMEKKC_00408 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BLMMEKKC_00409 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BLMMEKKC_00410 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BLMMEKKC_00411 8.9e-116 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BLMMEKKC_00412 2.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
BLMMEKKC_00413 1.8e-124 magIII L Base excision DNA repair protein, HhH-GPD family
BLMMEKKC_00414 3.3e-166 akr5f 1.1.1.346 S reductase
BLMMEKKC_00415 1.1e-74 C Aldo/keto reductase family
BLMMEKKC_00416 2.9e-14 C Aldo/keto reductase family
BLMMEKKC_00417 4.9e-204 xerS L Belongs to the 'phage' integrase family
BLMMEKKC_00418 6.7e-167 K Transcriptional regulator
BLMMEKKC_00419 3.7e-151
BLMMEKKC_00420 3.8e-162 degV S EDD domain protein, DegV family
BLMMEKKC_00421 3.8e-64
BLMMEKKC_00422 0.0 FbpA K Fibronectin-binding protein
BLMMEKKC_00423 4.9e-233 cycA E Amino acid permease
BLMMEKKC_00424 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BLMMEKKC_00425 5.1e-72
BLMMEKKC_00426 1.3e-99 4.1.1.44 S decarboxylase
BLMMEKKC_00427 0.0 S TerB-C domain
BLMMEKKC_00428 5.4e-253 P P-loop Domain of unknown function (DUF2791)
BLMMEKKC_00429 0.0 lhr L DEAD DEAH box helicase
BLMMEKKC_00430 1.4e-158 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
BLMMEKKC_00431 6.1e-160 rbsU U ribose uptake protein RbsU
BLMMEKKC_00432 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
BLMMEKKC_00433 1.8e-83 6.3.3.2 S ASCH
BLMMEKKC_00434 1.6e-137 2.4.2.3 F Phosphorylase superfamily
BLMMEKKC_00435 2.6e-88 2.3.1.57 K Acetyltransferase (GNAT) family
BLMMEKKC_00436 1.4e-98 rimL J Acetyltransferase (GNAT) domain
BLMMEKKC_00437 2.5e-43
BLMMEKKC_00438 2.7e-51 S endonuclease activity
BLMMEKKC_00439 3.6e-151 S Fic/DOC family
BLMMEKKC_00440 6e-143 3.1.3.48 T Tyrosine phosphatase family
BLMMEKKC_00442 1.4e-135
BLMMEKKC_00443 2.1e-63
BLMMEKKC_00444 1.6e-48 S MazG-like family
BLMMEKKC_00445 6.2e-104 S Protein of unknown function (DUF1211)
BLMMEKKC_00446 8.7e-75 K LytTr DNA-binding domain
BLMMEKKC_00447 3.7e-51 S Protein of unknown function (DUF3021)
BLMMEKKC_00448 2.1e-96 K Acetyltransferase (GNAT) domain
BLMMEKKC_00449 1.5e-130 ybbM S Uncharacterised protein family (UPF0014)
BLMMEKKC_00450 2.1e-109 ybbL S ABC transporter, ATP-binding protein
BLMMEKKC_00452 2e-74 3.6.4.12 S PD-(D/E)XK nuclease family transposase
BLMMEKKC_00453 1.7e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
BLMMEKKC_00454 1.8e-41 K peptidyl-tyrosine sulfation
BLMMEKKC_00455 2.6e-42
BLMMEKKC_00456 5.4e-47
BLMMEKKC_00457 5.9e-70 K Transcriptional regulator
BLMMEKKC_00458 1.1e-179 MA20_14895 S Conserved hypothetical protein 698
BLMMEKKC_00459 1.2e-63
BLMMEKKC_00460 1.6e-97 S LexA-binding, inner membrane-associated putative hydrolase
BLMMEKKC_00461 2.6e-98 K LysR substrate binding domain
BLMMEKKC_00462 4.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
BLMMEKKC_00463 2e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BLMMEKKC_00464 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BLMMEKKC_00465 2e-169 xerC D Phage integrase, N-terminal SAM-like domain
BLMMEKKC_00466 1.8e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BLMMEKKC_00467 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLMMEKKC_00468 5.8e-152 dprA LU DNA protecting protein DprA
BLMMEKKC_00469 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLMMEKKC_00470 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLMMEKKC_00471 1.1e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
BLMMEKKC_00472 2e-35 yozE S Belongs to the UPF0346 family
BLMMEKKC_00473 3.2e-150 DegV S Uncharacterised protein, DegV family COG1307
BLMMEKKC_00474 7.6e-115 hlyIII S protein, hemolysin III
BLMMEKKC_00475 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BLMMEKKC_00476 3.8e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMMEKKC_00477 9.2e-109
BLMMEKKC_00478 7.2e-92
BLMMEKKC_00479 0.0 1.3.5.4 C FMN_bind
BLMMEKKC_00480 0.0 S Protein of unknown function DUF262
BLMMEKKC_00481 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
BLMMEKKC_00482 2.7e-211 3.1.21.3 V Type I restriction modification DNA specificity domain
BLMMEKKC_00483 2.4e-178 L Belongs to the 'phage' integrase family
BLMMEKKC_00484 4.2e-195 3.1.21.3 V Type I restriction modification DNA specificity domain
BLMMEKKC_00485 1.8e-292 hsdM 2.1.1.72 V type I restriction-modification system
BLMMEKKC_00486 0.0 comEC S Competence protein ComEC
BLMMEKKC_00487 1.2e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
BLMMEKKC_00488 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
BLMMEKKC_00489 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BLMMEKKC_00490 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLMMEKKC_00491 7.7e-160
BLMMEKKC_00492 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BLMMEKKC_00493 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BLMMEKKC_00494 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BLMMEKKC_00495 1.2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
BLMMEKKC_00496 6.7e-89 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLMMEKKC_00497 7.4e-78
BLMMEKKC_00498 1.2e-70 S Domain of unknown function (DUF4767)
BLMMEKKC_00499 2.2e-224
BLMMEKKC_00500 1.1e-121 frnE Q DSBA-like thioredoxin domain
BLMMEKKC_00501 3.3e-180 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BLMMEKKC_00503 4.5e-76 S HIRAN
BLMMEKKC_00505 7.2e-164 htpX O Peptidase family M48
BLMMEKKC_00506 7e-32
BLMMEKKC_00507 1.4e-223 patA 2.6.1.1 E Aminotransferase
BLMMEKKC_00508 2.3e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
BLMMEKKC_00509 2.4e-144 E GDSL-like Lipase/Acylhydrolase family
BLMMEKKC_00510 3.8e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLMMEKKC_00511 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMMEKKC_00512 1e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
BLMMEKKC_00513 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
BLMMEKKC_00514 4.1e-40 yqeY S YqeY-like protein
BLMMEKKC_00515 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
BLMMEKKC_00516 1.2e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BLMMEKKC_00517 1.6e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BLMMEKKC_00518 1.6e-137 recO L Involved in DNA repair and RecF pathway recombination
BLMMEKKC_00519 3.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
BLMMEKKC_00520 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
BLMMEKKC_00521 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BLMMEKKC_00522 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BLMMEKKC_00523 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
BLMMEKKC_00524 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLMMEKKC_00525 1.4e-245 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
BLMMEKKC_00526 5.5e-112 tdk 2.7.1.21 F thymidine kinase
BLMMEKKC_00527 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BLMMEKKC_00528 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BLMMEKKC_00529 1e-187 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BLMMEKKC_00530 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BLMMEKKC_00531 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
BLMMEKKC_00532 2.1e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLMMEKKC_00533 8.4e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BLMMEKKC_00534 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLMMEKKC_00535 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BLMMEKKC_00536 3.1e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BLMMEKKC_00537 3.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BLMMEKKC_00538 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
BLMMEKKC_00539 2e-30 ywzB S Protein of unknown function (DUF1146)
BLMMEKKC_00540 2.2e-179 mbl D Cell shape determining protein MreB Mrl
BLMMEKKC_00541 2.5e-15 S DNA-directed RNA polymerase subunit beta
BLMMEKKC_00542 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
BLMMEKKC_00543 1.3e-34 S Protein of unknown function (DUF2969)
BLMMEKKC_00544 3.6e-224 rodA D Belongs to the SEDS family
BLMMEKKC_00545 5.2e-81 usp6 T universal stress protein
BLMMEKKC_00547 7.4e-239 rarA L recombination factor protein RarA
BLMMEKKC_00548 1e-81 yueI S Protein of unknown function (DUF1694)
BLMMEKKC_00549 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BLMMEKKC_00550 8.6e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
BLMMEKKC_00551 4.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
BLMMEKKC_00552 2.1e-168 2.7.1.2 GK ROK family
BLMMEKKC_00553 3.6e-165 rhaS6 K helix_turn_helix, arabinose operon control protein
BLMMEKKC_00554 2.7e-63 I Carboxylesterase family
BLMMEKKC_00555 6.9e-83 I Carboxylesterase family
BLMMEKKC_00556 2.2e-189 yhjX P Major Facilitator Superfamily
BLMMEKKC_00557 2.5e-306 S Predicted membrane protein (DUF2207)
BLMMEKKC_00558 5.2e-56 K Acetyltransferase (GNAT) domain
BLMMEKKC_00559 1.4e-59
BLMMEKKC_00560 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
BLMMEKKC_00561 1.2e-92 S ECF-type riboflavin transporter, S component
BLMMEKKC_00562 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
BLMMEKKC_00563 1.2e-12
BLMMEKKC_00564 6.3e-246 S Uncharacterized protein conserved in bacteria (DUF2325)
BLMMEKKC_00565 1.2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMMEKKC_00566 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
BLMMEKKC_00567 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
BLMMEKKC_00568 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
BLMMEKKC_00569 9.5e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
BLMMEKKC_00570 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BLMMEKKC_00571 2.2e-73 yqhY S Asp23 family, cell envelope-related function
BLMMEKKC_00572 8e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLMMEKKC_00573 8.1e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BLMMEKKC_00574 3.6e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BLMMEKKC_00575 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BLMMEKKC_00576 3.9e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BLMMEKKC_00577 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
BLMMEKKC_00578 1.7e-264 recN L May be involved in recombinational repair of damaged DNA
BLMMEKKC_00579 1.8e-47
BLMMEKKC_00580 4.7e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
BLMMEKKC_00581 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
BLMMEKKC_00582 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLMMEKKC_00583 7.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLMMEKKC_00584 1.2e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BLMMEKKC_00585 4.5e-140 stp 3.1.3.16 T phosphatase
BLMMEKKC_00586 0.0 KLT serine threonine protein kinase
BLMMEKKC_00587 1.4e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BLMMEKKC_00588 5.3e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
BLMMEKKC_00589 1e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
BLMMEKKC_00590 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
BLMMEKKC_00591 1.4e-57 asp S Asp23 family, cell envelope-related function
BLMMEKKC_00592 9.6e-308 yloV S DAK2 domain fusion protein YloV
BLMMEKKC_00593 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLMMEKKC_00594 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BLMMEKKC_00595 2.2e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLMMEKKC_00596 1.1e-192 oppD P Belongs to the ABC transporter superfamily
BLMMEKKC_00597 4.4e-180 oppF P Belongs to the ABC transporter superfamily
BLMMEKKC_00598 7.5e-180 oppB P ABC transporter permease
BLMMEKKC_00599 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
BLMMEKKC_00600 3.2e-30 oppA E ABC transporter substrate-binding protein
BLMMEKKC_00601 2.8e-298 oppA E ABC transporter substrate-binding protein
BLMMEKKC_00602 0.0 oppA E ABC transporter substrate-binding protein
BLMMEKKC_00603 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BLMMEKKC_00604 0.0 smc D Required for chromosome condensation and partitioning
BLMMEKKC_00605 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BLMMEKKC_00606 6.1e-287 pipD E Dipeptidase
BLMMEKKC_00607 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BLMMEKKC_00608 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BLMMEKKC_00609 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
BLMMEKKC_00610 7.4e-97 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BLMMEKKC_00611 2.2e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
BLMMEKKC_00612 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BLMMEKKC_00613 9.3e-118 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BLMMEKKC_00614 6.5e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
BLMMEKKC_00615 1.1e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
BLMMEKKC_00616 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BLMMEKKC_00617 1.5e-34 ynzC S UPF0291 protein
BLMMEKKC_00618 1.5e-30 yneF S Uncharacterised protein family (UPF0154)
BLMMEKKC_00619 0.0 mdlA V ABC transporter
BLMMEKKC_00620 6.1e-300 mdlB V ABC transporter
BLMMEKKC_00621 8.6e-201 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
BLMMEKKC_00622 9.8e-117 plsC 2.3.1.51 I Acyltransferase
BLMMEKKC_00623 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
BLMMEKKC_00624 2.2e-179 K Transcriptional regulator
BLMMEKKC_00625 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
BLMMEKKC_00626 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
BLMMEKKC_00627 7.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLMMEKKC_00628 7.2e-124 yoaK S Protein of unknown function (DUF1275)
BLMMEKKC_00629 1.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BLMMEKKC_00630 7.8e-216 iscS2 2.8.1.7 E Aminotransferase class V
BLMMEKKC_00631 5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMMEKKC_00632 7.8e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BLMMEKKC_00633 4.2e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
BLMMEKKC_00634 0.0 3.6.3.8 P P-type ATPase
BLMMEKKC_00635 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BLMMEKKC_00636 2.8e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BLMMEKKC_00637 9.2e-124 S Haloacid dehalogenase-like hydrolase
BLMMEKKC_00638 9.5e-112 radC L DNA repair protein
BLMMEKKC_00639 6.4e-166 mreB D cell shape determining protein MreB
BLMMEKKC_00640 1e-143 mreC M Involved in formation and maintenance of cell shape
BLMMEKKC_00641 5.4e-95 mreD
BLMMEKKC_00642 3.6e-13 S Protein of unknown function (DUF4044)
BLMMEKKC_00643 6.1e-52 S Protein of unknown function (DUF3397)
BLMMEKKC_00644 4.1e-77 mraZ K Belongs to the MraZ family
BLMMEKKC_00645 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BLMMEKKC_00646 6.3e-55 ftsL D Cell division protein FtsL
BLMMEKKC_00647 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
BLMMEKKC_00648 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLMMEKKC_00649 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLMMEKKC_00650 3.6e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMMEKKC_00651 6.3e-154 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BLMMEKKC_00652 2.7e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BLMMEKKC_00653 4.9e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLMMEKKC_00654 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
BLMMEKKC_00655 2e-27 yggT S YGGT family
BLMMEKKC_00656 4.8e-148 ylmH S S4 domain protein
BLMMEKKC_00657 2.1e-119 gpsB D DivIVA domain protein
BLMMEKKC_00658 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BLMMEKKC_00659 2e-32 cspA K 'Cold-shock' DNA-binding domain
BLMMEKKC_00660 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
BLMMEKKC_00662 1.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLMMEKKC_00663 3.3e-214 iscS 2.8.1.7 E Aminotransferase class V
BLMMEKKC_00664 1.6e-57 XK27_04120 S Putative amino acid metabolism
BLMMEKKC_00665 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BLMMEKKC_00666 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
BLMMEKKC_00667 5.1e-116 S Repeat protein
BLMMEKKC_00668 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BLMMEKKC_00669 9.9e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
BLMMEKKC_00670 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLMMEKKC_00671 3e-34 ykzG S Belongs to the UPF0356 family
BLMMEKKC_00672 1.2e-143 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
BLMMEKKC_00673 3.2e-103 yagU S Protein of unknown function (DUF1440)
BLMMEKKC_00674 4.1e-147 S hydrolase
BLMMEKKC_00675 2.4e-104 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLMMEKKC_00677 5e-09
BLMMEKKC_00680 1.4e-84 S DNA primase
BLMMEKKC_00681 1.9e-35 S Primase C terminal 1 (PriCT-1)
BLMMEKKC_00682 2.9e-28
BLMMEKKC_00684 1.5e-10
BLMMEKKC_00686 4.8e-20
BLMMEKKC_00687 7.3e-13 S sequence-specific DNA binding
BLMMEKKC_00688 1.4e-132 sip L Belongs to the 'phage' integrase family
BLMMEKKC_00689 1.8e-47 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
BLMMEKKC_00690 5.9e-219 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
BLMMEKKC_00691 8.3e-232 S Peptidase M16
BLMMEKKC_00692 1.6e-129 IQ Enoyl-(Acyl carrier protein) reductase
BLMMEKKC_00693 4.3e-125 ymfM S Helix-turn-helix domain
BLMMEKKC_00694 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLMMEKKC_00695 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BLMMEKKC_00696 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
BLMMEKKC_00697 2.7e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
BLMMEKKC_00698 2.5e-118 yvyE 3.4.13.9 S YigZ family
BLMMEKKC_00699 1.1e-242 comFA L Helicase C-terminal domain protein
BLMMEKKC_00700 5.7e-126 comFC S Competence protein
BLMMEKKC_00701 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLMMEKKC_00702 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BLMMEKKC_00703 6.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLMMEKKC_00704 2.5e-35
BLMMEKKC_00705 3.8e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BLMMEKKC_00706 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BLMMEKKC_00707 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
BLMMEKKC_00708 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BLMMEKKC_00709 0.0 S domain, Protein
BLMMEKKC_00711 3.9e-23 bamA UW LPXTG-motif cell wall anchor domain protein
BLMMEKKC_00712 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
BLMMEKKC_00714 3.2e-138 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
BLMMEKKC_00715 1e-76 M Protein of unknown function (DUF3737)
BLMMEKKC_00716 1.8e-80 patB 4.4.1.8 E Aminotransferase, class I
BLMMEKKC_00717 2.9e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
BLMMEKKC_00718 9.2e-68 S SdpI/YhfL protein family
BLMMEKKC_00719 9e-130 K Transcriptional regulatory protein, C terminal
BLMMEKKC_00720 5.3e-270 T PhoQ Sensor
BLMMEKKC_00721 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
BLMMEKKC_00722 1.4e-107 vanZ V VanZ like family
BLMMEKKC_00723 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
BLMMEKKC_00724 2e-205 EGP Major facilitator Superfamily
BLMMEKKC_00725 1.4e-72
BLMMEKKC_00728 7.2e-197 ampC V Beta-lactamase
BLMMEKKC_00729 4.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)