ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMDKBHPH_00001 8.9e-145 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMDKBHPH_00002 3.4e-76 S PAS domain
HMDKBHPH_00003 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HMDKBHPH_00004 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMDKBHPH_00005 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HMDKBHPH_00006 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HMDKBHPH_00007 4.2e-26 msmX P Belongs to the ABC transporter superfamily
HMDKBHPH_00008 3e-187 mdlB V ABC transporter
HMDKBHPH_00009 2.4e-111 pepO 3.4.24.71 O Peptidase family M13
HMDKBHPH_00010 5.3e-249 dtpT U amino acid peptide transporter
HMDKBHPH_00011 2e-74 comFA L Helicase C-terminal domain protein
HMDKBHPH_00012 1.6e-117 yvyE 3.4.13.9 S YigZ family
HMDKBHPH_00013 1.1e-44 tagO 2.7.8.33, 2.7.8.35 M transferase
HMDKBHPH_00014 1.7e-45 yggT S YGGT family
HMDKBHPH_00015 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMDKBHPH_00016 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMDKBHPH_00017 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMDKBHPH_00018 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMDKBHPH_00019 2.1e-82 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMDKBHPH_00020 5.2e-20 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMDKBHPH_00021 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMDKBHPH_00022 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMDKBHPH_00023 3.1e-192 oppD P Belongs to the ABC transporter superfamily
HMDKBHPH_00024 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMDKBHPH_00025 1.2e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMDKBHPH_00026 1.1e-292 L Nuclease-related domain
HMDKBHPH_00027 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMDKBHPH_00028 4.7e-38
HMDKBHPH_00029 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMDKBHPH_00030 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
HMDKBHPH_00031 2.8e-135
HMDKBHPH_00032 1.3e-258 glnPH2 P ABC transporter permease
HMDKBHPH_00033 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMDKBHPH_00034 6.4e-224 S Cysteine-rich secretory protein family
HMDKBHPH_00035 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMDKBHPH_00036 1.4e-112
HMDKBHPH_00037 2.2e-202 yibE S overlaps another CDS with the same product name
HMDKBHPH_00038 4.9e-129 yibF S overlaps another CDS with the same product name
HMDKBHPH_00039 8.7e-145 I alpha/beta hydrolase fold
HMDKBHPH_00040 0.0 G Belongs to the glycosyl hydrolase 31 family
HMDKBHPH_00041 1.4e-95 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMDKBHPH_00042 2.3e-23 S Protein of unknown function (DUF2929)
HMDKBHPH_00043 2.2e-210 dnaE 2.7.7.7 L DNA polymerase
HMDKBHPH_00044 9.2e-124 S Haloacid dehalogenase-like hydrolase
HMDKBHPH_00045 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMDKBHPH_00046 2.3e-21 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMDKBHPH_00047 3.4e-117 S Peptidase family M23
HMDKBHPH_00048 1e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMDKBHPH_00049 2.2e-69 lysA2 M Glycosyl hydrolases family 25
HMDKBHPH_00053 1e-78 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMDKBHPH_00054 1e-134 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMDKBHPH_00056 4.3e-47 pspC KT PspC domain
HMDKBHPH_00057 8.5e-199 ytgP S Polysaccharide biosynthesis protein
HMDKBHPH_00058 2.6e-75 ypbG 2.7.1.2 GK ROK family
HMDKBHPH_00059 5.8e-274 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMDKBHPH_00060 1.9e-10 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDKBHPH_00061 6.7e-185 ydaM M Glycosyl transferase
HMDKBHPH_00062 1.8e-177 G Glycosyl hydrolases family 8
HMDKBHPH_00063 1e-119 yfbR S HD containing hydrolase-like enzyme
HMDKBHPH_00064 2.6e-160 L HNH nucleases
HMDKBHPH_00065 3.3e-148 S Protein of unknown function (DUF805)
HMDKBHPH_00066 3.4e-135 glnQ E ABC transporter, ATP-binding protein
HMDKBHPH_00067 1.3e-290 glnP P ABC transporter permease
HMDKBHPH_00068 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMDKBHPH_00069 5.8e-64 yeaO S Protein of unknown function, DUF488
HMDKBHPH_00070 1.3e-124 terC P Integral membrane protein TerC family
HMDKBHPH_00071 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HMDKBHPH_00072 1.2e-109
HMDKBHPH_00073 4.6e-274 ycaM E amino acid
HMDKBHPH_00074 3.1e-139 S Cysteine-rich secretory protein family
HMDKBHPH_00075 4.2e-77 K MerR HTH family regulatory protein
HMDKBHPH_00076 1e-260 lmrB EGP Major facilitator Superfamily
HMDKBHPH_00077 3.1e-48 S Domain of unknown function (DUF4811)
HMDKBHPH_00078 3.7e-35 L Psort location Cytoplasmic, score
HMDKBHPH_00079 3.4e-24 relB L Addiction module antitoxin, RelB DinJ family
HMDKBHPH_00080 8.1e-17 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMDKBHPH_00082 2.8e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMDKBHPH_00084 1.8e-23 S CAAX protease self-immunity
HMDKBHPH_00085 1.1e-34
HMDKBHPH_00086 1e-66 doc S Fic/DOC family
HMDKBHPH_00088 8.7e-242 V N-6 DNA Methylase
HMDKBHPH_00089 6.5e-82 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HMDKBHPH_00090 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMDKBHPH_00091 5e-39 relB L RelB antitoxin
HMDKBHPH_00093 2.2e-97 D VirC1 protein
HMDKBHPH_00094 5e-15 S Domain of Unknown Function with PDB structure (DUF3850)
HMDKBHPH_00096 1e-12
HMDKBHPH_00097 7.6e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMDKBHPH_00098 1.3e-88 M Protein of unknown function (DUF3737)
HMDKBHPH_00099 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMDKBHPH_00100 8.3e-60 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMDKBHPH_00101 5.1e-122 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMDKBHPH_00102 1.6e-92 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMDKBHPH_00103 1.6e-199 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HMDKBHPH_00104 1.8e-171 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMDKBHPH_00105 2.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
HMDKBHPH_00106 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HMDKBHPH_00110 1.1e-65 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMDKBHPH_00111 5.5e-36
HMDKBHPH_00112 1.6e-158 scrR K Periplasmic binding protein domain
HMDKBHPH_00113 5.7e-200 msmE G Bacterial extracellular solute-binding protein
HMDKBHPH_00114 4.8e-157 msmF P Binding-protein-dependent transport system inner membrane component
HMDKBHPH_00115 2e-152 msmG P Binding-protein-dependent transport system inner membrane component
HMDKBHPH_00116 3.1e-209 msmX P Belongs to the ABC transporter superfamily
HMDKBHPH_00117 2.7e-146 rafA 3.2.1.22 G alpha-galactosidase
HMDKBHPH_00118 2e-64 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HMDKBHPH_00121 1.1e-194 ampC V Beta-lactamase
HMDKBHPH_00122 6.6e-158 EGP Major facilitator Superfamily
HMDKBHPH_00123 2.2e-135 lysR5 K LysR substrate binding domain
HMDKBHPH_00124 1.8e-96 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HMDKBHPH_00125 3.9e-93 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMDKBHPH_00126 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMDKBHPH_00127 3.2e-30 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMDKBHPH_00128 7.5e-242 cycA E Amino acid permease
HMDKBHPH_00129 1.3e-85 maa S transferase hexapeptide repeat
HMDKBHPH_00130 1.3e-157 K Transcriptional regulator
HMDKBHPH_00131 6.6e-34 manO S Domain of unknown function (DUF956)
HMDKBHPH_00132 1.5e-56 asp S Asp23 family, cell envelope-related function
HMDKBHPH_00133 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMDKBHPH_00134 1.4e-30
HMDKBHPH_00135 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMDKBHPH_00136 1.2e-94
HMDKBHPH_00137 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HMDKBHPH_00138 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMDKBHPH_00139 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMDKBHPH_00140 5e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMDKBHPH_00141 1e-99 yagE E Amino acid permease
HMDKBHPH_00142 4.3e-86 3.4.21.96 S SLAP domain
HMDKBHPH_00143 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMDKBHPH_00144 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMDKBHPH_00145 1.2e-107 hlyIII S protein, hemolysin III
HMDKBHPH_00146 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
HMDKBHPH_00147 6.5e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMDKBHPH_00148 1.6e-199 pbpX V Beta-lactamase
HMDKBHPH_00149 1.3e-230 nhaC C Na H antiporter NhaC
HMDKBHPH_00150 4.5e-50
HMDKBHPH_00151 1.2e-105 ybhL S Belongs to the BI1 family
HMDKBHPH_00152 1.5e-65 K transcriptional regulator
HMDKBHPH_00153 7.2e-18
HMDKBHPH_00154 1.1e-169 yegS 2.7.1.107 G Lipid kinase
HMDKBHPH_00155 9.2e-206 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMDKBHPH_00156 2.3e-31 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
HMDKBHPH_00157 2.1e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMDKBHPH_00158 2.3e-215 S Sterol carrier protein domain
HMDKBHPH_00159 2.2e-12
HMDKBHPH_00160 1.3e-34 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMDKBHPH_00161 2.1e-32
HMDKBHPH_00162 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HMDKBHPH_00163 2.3e-156 K Helix-turn-helix XRE-family like proteins
HMDKBHPH_00164 3.9e-298 V ABC transporter transmembrane region
HMDKBHPH_00165 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HMDKBHPH_00166 0.0 S TerB-C domain
HMDKBHPH_00167 3.5e-244 P P-loop Domain of unknown function (DUF2791)
HMDKBHPH_00168 0.0 lhr L DEAD DEAH box helicase
HMDKBHPH_00169 1.4e-60
HMDKBHPH_00170 1.6e-227 amtB P ammonium transporter
HMDKBHPH_00171 8.7e-131 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMDKBHPH_00173 6.2e-59 psiE S Phosphate-starvation-inducible E
HMDKBHPH_00174 1.1e-109 yncA 2.3.1.79 S Maltose acetyltransferase
HMDKBHPH_00175 2.9e-69 S Iron-sulphur cluster biosynthesis
HMDKBHPH_00177 5.1e-30
HMDKBHPH_00178 1e-31 K SIS domain
HMDKBHPH_00179 6.7e-228 slpX S SLAP domain
HMDKBHPH_00180 3.7e-22 3.6.4.12 S transposase or invertase
HMDKBHPH_00181 7.7e-12
HMDKBHPH_00182 1.1e-240 npr 1.11.1.1 C NADH oxidase
HMDKBHPH_00185 1.9e-300 oppA2 E ABC transporter, substratebinding protein
HMDKBHPH_00186 5.6e-179
HMDKBHPH_00187 4.6e-123 gntR1 K UTRA
HMDKBHPH_00188 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HMDKBHPH_00189 8.3e-90 XK27_00915 C Luciferase-like monooxygenase
HMDKBHPH_00190 6.5e-87 K GNAT family
HMDKBHPH_00191 6.8e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HMDKBHPH_00193 1.5e-36
HMDKBHPH_00194 1.4e-90 P ABC transporter
HMDKBHPH_00195 1.5e-181 P ABC transporter
HMDKBHPH_00196 5.4e-13
HMDKBHPH_00197 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMDKBHPH_00198 1.7e-201 oppA E ABC transporter
HMDKBHPH_00199 2.2e-229 Q Imidazolonepropionase and related amidohydrolases
HMDKBHPH_00200 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
HMDKBHPH_00201 3e-137 S Protein of unknown function (DUF3100)
HMDKBHPH_00202 5.7e-46 S An automated process has identified a potential problem with this gene model
HMDKBHPH_00203 4e-36 S Cytochrome B5
HMDKBHPH_00204 1.7e-167 arbZ I Phosphate acyltransferases
HMDKBHPH_00205 8.7e-181 arbY M Glycosyl transferase family 8
HMDKBHPH_00206 1.5e-143 arbY M Glycosyl transferase family 8
HMDKBHPH_00207 5.8e-73 S domain protein
HMDKBHPH_00209 4.9e-251 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HMDKBHPH_00210 3e-145 potD2 P ABC transporter
HMDKBHPH_00211 3.5e-84 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMDKBHPH_00212 4e-42 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMDKBHPH_00213 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component
HMDKBHPH_00214 3.4e-71 holB 2.7.7.7 L DNA polymerase III
HMDKBHPH_00215 1.8e-59 yabA L Involved in initiation control of chromosome replication
HMDKBHPH_00216 2.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMDKBHPH_00217 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMDKBHPH_00219 6.3e-304 E Amino acid permease
HMDKBHPH_00220 2.3e-44 D Alpha beta
HMDKBHPH_00222 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMDKBHPH_00224 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMDKBHPH_00225 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HMDKBHPH_00226 3.7e-88 G Histidine phosphatase superfamily (branch 1)
HMDKBHPH_00227 7.2e-46 G Phosphoglycerate mutase family
HMDKBHPH_00228 8.3e-37 G Phosphoglycerate mutase family
HMDKBHPH_00229 4.7e-159 D nuclear chromosome segregation
HMDKBHPH_00230 5.8e-78 M LysM domain protein
HMDKBHPH_00231 1.6e-43 1.3.5.4 C FAD binding domain
HMDKBHPH_00232 2.1e-51 ndh 1.6.99.3 C NADH dehydrogenase
HMDKBHPH_00233 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
HMDKBHPH_00234 7.8e-157 S reductase
HMDKBHPH_00235 2e-29
HMDKBHPH_00236 2.9e-287 K Putative DNA-binding domain
HMDKBHPH_00237 2.9e-238 pyrP F Permease
HMDKBHPH_00238 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMDKBHPH_00239 1.7e-260 emrY EGP Major facilitator Superfamily
HMDKBHPH_00240 2.2e-76 mdtG EGP Major facilitator Superfamily
HMDKBHPH_00241 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMDKBHPH_00242 2.6e-214 yubA S AI-2E family transporter
HMDKBHPH_00243 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMDKBHPH_00244 4e-101 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMDKBHPH_00245 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMDKBHPH_00246 7.1e-46
HMDKBHPH_00247 4e-148 glcU U sugar transport
HMDKBHPH_00248 2.1e-248 lctP C L-lactate permease
HMDKBHPH_00249 7.4e-229 steT_1 E amino acid
HMDKBHPH_00250 2.2e-139 puuD S peptidase C26
HMDKBHPH_00252 2.3e-74 pipD E Dipeptidase
HMDKBHPH_00254 3.4e-23
HMDKBHPH_00255 8.5e-131 cysA V ABC transporter, ATP-binding protein
HMDKBHPH_00256 0.0 V FtsX-like permease family
HMDKBHPH_00257 2.1e-61 yfnA E amino acid
HMDKBHPH_00258 2.3e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMDKBHPH_00259 3.6e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HMDKBHPH_00260 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HMDKBHPH_00261 2.1e-138 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMDKBHPH_00263 2.8e-162 ynbB 4.4.1.1 P aluminum resistance
HMDKBHPH_00264 3.4e-274 pipD E Dipeptidase
HMDKBHPH_00265 2e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HMDKBHPH_00266 3.3e-176 hrtB V ABC transporter permease
HMDKBHPH_00267 2.7e-91 ygfC K Bacterial regulatory proteins, tetR family
HMDKBHPH_00268 3.5e-111 G phosphoglycerate mutase
HMDKBHPH_00269 4.6e-140 aroD S Alpha/beta hydrolase family
HMDKBHPH_00270 2.2e-142 S Belongs to the UPF0246 family
HMDKBHPH_00271 2.6e-120
HMDKBHPH_00272 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
HMDKBHPH_00273 2e-79 S helix_turn_helix, Deoxyribose operon repressor
HMDKBHPH_00274 3.3e-140 repB EP Plasmid replication protein
HMDKBHPH_00275 2.2e-22
HMDKBHPH_00276 3.6e-103 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMDKBHPH_00277 1.1e-34 S Protein of unknown function (DUF2508)
HMDKBHPH_00278 2.4e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMDKBHPH_00279 4.8e-108 patA 2.6.1.1 E Aminotransferase
HMDKBHPH_00281 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMDKBHPH_00282 3.5e-54 trxA O Belongs to the thioredoxin family
HMDKBHPH_00283 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMDKBHPH_00284 1.1e-50 yrzB S Belongs to the UPF0473 family
HMDKBHPH_00285 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMDKBHPH_00286 2e-42 yrzL S Belongs to the UPF0297 family
HMDKBHPH_00287 1.4e-184 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMDKBHPH_00289 1.9e-245 L Transposase IS66 family
HMDKBHPH_00290 8.7e-34 S Transposase C of IS166 homeodomain
HMDKBHPH_00291 9.3e-64 L PFAM IS66 Orf2 family protein
HMDKBHPH_00292 7.7e-22
HMDKBHPH_00293 2.1e-64 fhaB M Rib/alpha-like repeat
HMDKBHPH_00294 3.7e-149 fhaB M Rib/alpha-like repeat
HMDKBHPH_00295 5.7e-94 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMDKBHPH_00296 1.3e-113 tdk 2.7.1.21 F thymidine kinase
HMDKBHPH_00297 1.6e-108 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMDKBHPH_00298 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMDKBHPH_00299 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMDKBHPH_00300 1.8e-71 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMDKBHPH_00301 1.8e-112 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMDKBHPH_00302 2e-37 scrR K Periplasmic binding protein domain
HMDKBHPH_00303 2.1e-33 scrR K Periplasmic binding protein domain
HMDKBHPH_00304 1.1e-164 S Protein of unknown function (DUF2974)
HMDKBHPH_00305 6.8e-108 glnP P ABC transporter permease
HMDKBHPH_00306 9.7e-91 gluC P ABC transporter permease
HMDKBHPH_00307 3.4e-149 glnH ET ABC transporter substrate-binding protein
HMDKBHPH_00308 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMDKBHPH_00309 4.7e-114 udk 2.7.1.48 F Zeta toxin
HMDKBHPH_00310 2.3e-151 G MFS/sugar transport protein
HMDKBHPH_00311 4.7e-85 G MFS/sugar transport protein
HMDKBHPH_00312 8.4e-102 S ABC-type cobalt transport system, permease component
HMDKBHPH_00313 0.0 V ABC transporter transmembrane region
HMDKBHPH_00314 1.5e-308 XK27_09600 V ABC transporter, ATP-binding protein
HMDKBHPH_00315 1.4e-80 K Transcriptional regulator, MarR family
HMDKBHPH_00316 1.9e-147 glnH ET ABC transporter
HMDKBHPH_00317 3.5e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
HMDKBHPH_00318 8.6e-243 steT E amino acid
HMDKBHPH_00319 9.8e-239 steT E amino acid
HMDKBHPH_00320 6.1e-151
HMDKBHPH_00321 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMDKBHPH_00322 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMDKBHPH_00323 3.4e-129 S (CBS) domain
HMDKBHPH_00324 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMDKBHPH_00325 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMDKBHPH_00326 4.8e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMDKBHPH_00327 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMDKBHPH_00328 2.5e-39 rpmE2 J Ribosomal protein L31
HMDKBHPH_00329 3.4e-213 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HMDKBHPH_00330 3.5e-99 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HMDKBHPH_00331 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HMDKBHPH_00332 9.5e-297 ybeC E amino acid
HMDKBHPH_00333 2.7e-08 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMDKBHPH_00334 6.2e-12
HMDKBHPH_00335 1.8e-125 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDKBHPH_00336 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDKBHPH_00337 2.3e-101 xth 3.1.11.2 L exodeoxyribonuclease III
HMDKBHPH_00338 1.3e-273 E amino acid
HMDKBHPH_00339 0.0 L Helicase C-terminal domain protein
HMDKBHPH_00340 4.8e-205 pbpX1 V Beta-lactamase
HMDKBHPH_00341 2.4e-206 N Uncharacterized conserved protein (DUF2075)
HMDKBHPH_00342 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMDKBHPH_00344 2.2e-25 K Helix-turn-helix domain
HMDKBHPH_00345 5e-08 S Pfam:DUF955
HMDKBHPH_00346 6.5e-151 L Belongs to the 'phage' integrase family
HMDKBHPH_00348 7e-173 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMDKBHPH_00349 9.1e-302 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMDKBHPH_00350 2e-73 D Alpha beta
HMDKBHPH_00351 1.1e-56 S Protein of unknown function (DUF3290)
HMDKBHPH_00352 3e-116 yviA S Protein of unknown function (DUF421)
HMDKBHPH_00353 5.8e-157 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMDKBHPH_00354 1e-181 dnaQ 2.7.7.7 L EXOIII
HMDKBHPH_00355 3.4e-77 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMDKBHPH_00356 7.7e-293 I Acyltransferase
HMDKBHPH_00357 2.7e-46 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMDKBHPH_00358 4.4e-129 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMDKBHPH_00359 1.8e-139 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMDKBHPH_00360 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMDKBHPH_00361 6.8e-231 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HMDKBHPH_00362 7.8e-62 L HNH nucleases
HMDKBHPH_00363 1.1e-08
HMDKBHPH_00369 3.9e-18 K AntA/AntB antirepressor
HMDKBHPH_00370 1.5e-155 arbx M Glycosyl transferase family 8
HMDKBHPH_00371 4.2e-149 arbV 2.3.1.51 I Acyl-transferase
HMDKBHPH_00373 4.9e-34
HMDKBHPH_00375 4.8e-131 K response regulator
HMDKBHPH_00376 2.9e-305 vicK 2.7.13.3 T Histidine kinase
HMDKBHPH_00377 3.3e-258 yycH S YycH protein
HMDKBHPH_00378 3.4e-149 yycI S YycH protein
HMDKBHPH_00379 4.1e-147 vicX 3.1.26.11 S domain protein
HMDKBHPH_00380 1.6e-161 htrA 3.4.21.107 O serine protease
HMDKBHPH_00381 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMDKBHPH_00382 6.2e-157 cjaA ET ABC transporter substrate-binding protein
HMDKBHPH_00383 2.4e-125 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMDKBHPH_00384 2.4e-176 mreB D cell shape determining protein MreB
HMDKBHPH_00385 2.5e-107 radC L DNA repair protein
HMDKBHPH_00386 1.5e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMDKBHPH_00387 1.8e-62 yabR J S1 RNA binding domain
HMDKBHPH_00388 6.8e-60 divIC D Septum formation initiator
HMDKBHPH_00389 1.6e-33 yabO J S4 domain protein
HMDKBHPH_00390 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMDKBHPH_00391 1.3e-70 tnpB L Putative transposase DNA-binding domain
HMDKBHPH_00392 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMDKBHPH_00393 1.6e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMDKBHPH_00394 2.9e-204 csaB M Glycosyl transferases group 1
HMDKBHPH_00395 1.2e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMDKBHPH_00396 1e-284 uvrA3 L excinuclease ABC, A subunit
HMDKBHPH_00398 4.4e-40 ropB K Helix-turn-helix domain
HMDKBHPH_00399 1.5e-36 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMDKBHPH_00400 1.6e-33 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMDKBHPH_00401 2e-141 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMDKBHPH_00402 1.1e-71 yslB S Protein of unknown function (DUF2507)
HMDKBHPH_00403 1.6e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMDKBHPH_00404 8.7e-195 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMDKBHPH_00405 3.7e-91 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMDKBHPH_00406 8.6e-199 tnpB L Putative transposase DNA-binding domain
HMDKBHPH_00407 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMDKBHPH_00408 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMDKBHPH_00409 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMDKBHPH_00410 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMDKBHPH_00411 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMDKBHPH_00412 3.1e-115 mmuP E amino acid
HMDKBHPH_00413 3.7e-102 pepV 3.5.1.18 E dipeptidase PepV
HMDKBHPH_00414 4.6e-83 S hydrolase
HMDKBHPH_00415 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMDKBHPH_00416 1.7e-29 secG U Preprotein translocase
HMDKBHPH_00417 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMDKBHPH_00418 4.8e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HMDKBHPH_00419 8.2e-134 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HMDKBHPH_00420 2.2e-85 S ECF transporter, substrate-specific component
HMDKBHPH_00421 2.4e-60 fat 3.1.2.21 I Acyl-ACP thioesterase
HMDKBHPH_00422 3.4e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HMDKBHPH_00423 1.5e-43
HMDKBHPH_00424 2.7e-285 lsa S ABC transporter
HMDKBHPH_00425 1.9e-50 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HMDKBHPH_00426 2.7e-58 metQ1 P Belongs to the nlpA lipoprotein family
HMDKBHPH_00427 8.2e-24
HMDKBHPH_00428 2.3e-164 mco Q Multicopper oxidase
HMDKBHPH_00429 7.9e-132 rpsA 1.17.7.4 J Ribosomal protein S1
HMDKBHPH_00430 3e-54 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMDKBHPH_00431 3e-41 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMDKBHPH_00432 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMDKBHPH_00433 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMDKBHPH_00434 9e-161 V ABC transporter transmembrane region
HMDKBHPH_00435 7e-68 V ABC transporter transmembrane region
HMDKBHPH_00436 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
HMDKBHPH_00437 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HMDKBHPH_00438 2.5e-72 S Peptidase propeptide and YPEB domain
HMDKBHPH_00439 5.8e-76 S Peptidase propeptide and YPEB domain
HMDKBHPH_00440 5.2e-187 T GHKL domain
HMDKBHPH_00441 3.1e-130 T Transcriptional regulatory protein, C terminal
HMDKBHPH_00442 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HMDKBHPH_00443 2.9e-277 V ABC transporter transmembrane region
HMDKBHPH_00444 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMDKBHPH_00445 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
HMDKBHPH_00446 9.9e-124 S PAS domain
HMDKBHPH_00447 1.6e-11
HMDKBHPH_00448 2.7e-57
HMDKBHPH_00449 6.6e-56
HMDKBHPH_00450 1.1e-239 oppA3 E ABC transporter, substratebinding protein
HMDKBHPH_00452 8.7e-19 spaC2 V Lanthionine synthetase C-like protein
HMDKBHPH_00453 3.4e-99
HMDKBHPH_00454 1.4e-133
HMDKBHPH_00455 3.1e-100 V ATPases associated with a variety of cellular activities
HMDKBHPH_00456 1.3e-146 ykuT M mechanosensitive ion channel
HMDKBHPH_00457 2.8e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMDKBHPH_00458 1.3e-36
HMDKBHPH_00459 6.3e-20 mreC M Involved in formation and maintenance of cell shape
HMDKBHPH_00460 2.7e-94 mreD
HMDKBHPH_00462 6.4e-54 S Protein of unknown function (DUF3397)
HMDKBHPH_00463 4.5e-76 mraZ K Belongs to the MraZ family
HMDKBHPH_00464 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMDKBHPH_00465 8.1e-184 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMDKBHPH_00466 2e-106 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMDKBHPH_00467 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMDKBHPH_00468 1e-76 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMDKBHPH_00469 1.1e-273 arlS 2.7.13.3 T Histidine kinase
HMDKBHPH_00470 1e-12
HMDKBHPH_00471 1.6e-99 S CAAX protease self-immunity
HMDKBHPH_00472 6.1e-224 S SLAP domain
HMDKBHPH_00473 1.3e-82 S Aminoacyl-tRNA editing domain
HMDKBHPH_00474 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMDKBHPH_00475 2.4e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMDKBHPH_00476 7.7e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMDKBHPH_00477 4.5e-58 yodB K Transcriptional regulator, HxlR family
HMDKBHPH_00479 2.7e-107 papP P ABC transporter, permease protein
HMDKBHPH_00480 2e-64 cggR K Putative sugar-binding domain
HMDKBHPH_00481 1.4e-113 cggR K Putative sugar-binding domain
HMDKBHPH_00483 1e-153
HMDKBHPH_00484 9e-119
HMDKBHPH_00485 1.4e-13 hicA S HicA toxin of bacterial toxin-antitoxin,
HMDKBHPH_00486 1.2e-31 S protein encoded in hypervariable junctions of pilus gene clusters
HMDKBHPH_00488 2.1e-34
HMDKBHPH_00489 1.4e-155 S interspecies interaction between organisms
HMDKBHPH_00491 1.1e-11 GT2,GT4 M family 8
HMDKBHPH_00492 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMDKBHPH_00493 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMDKBHPH_00494 5.1e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HMDKBHPH_00495 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
HMDKBHPH_00496 9e-26
HMDKBHPH_00497 6.4e-55 E GDSL-like Lipase/Acylhydrolase
HMDKBHPH_00498 2.3e-25 M domain protein
HMDKBHPH_00499 1.1e-84 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMDKBHPH_00500 1.4e-253 typA T GTP-binding protein TypA
HMDKBHPH_00501 1.3e-210 ftsW D Belongs to the SEDS family
HMDKBHPH_00502 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HMDKBHPH_00503 3.8e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HMDKBHPH_00504 1.1e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMDKBHPH_00505 2e-16 ylbL T Belongs to the peptidase S16 family
HMDKBHPH_00506 4.3e-208 pepA E M42 glutamyl aminopeptidase
HMDKBHPH_00507 1.9e-43
HMDKBHPH_00508 6.9e-136
HMDKBHPH_00509 2e-215 lacS G Transporter
HMDKBHPH_00510 1.2e-39 lacZ 3.2.1.23 G -beta-galactosidase
HMDKBHPH_00511 5.5e-251 lacZ 3.2.1.23 G -beta-galactosidase
HMDKBHPH_00512 9.3e-124 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMDKBHPH_00513 1.2e-296 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMDKBHPH_00514 1.9e-152 ansA 3.5.1.1 EJ L-asparaginase, type I
HMDKBHPH_00515 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
HMDKBHPH_00516 3.3e-266 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HMDKBHPH_00517 1.5e-152
HMDKBHPH_00518 1e-95
HMDKBHPH_00519 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
HMDKBHPH_00521 1.3e-184 3.2.1.18 GH33 M Rib/alpha-like repeat
HMDKBHPH_00522 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
HMDKBHPH_00523 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMDKBHPH_00525 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMDKBHPH_00526 2.4e-43 K Helix-turn-helix
HMDKBHPH_00527 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMDKBHPH_00528 1.4e-226 pbuX F xanthine permease
HMDKBHPH_00529 2.5e-152 msmR K AraC-like ligand binding domain
HMDKBHPH_00530 2.4e-166 pipD E Dipeptidase
HMDKBHPH_00531 1.3e-78 pipD E Dipeptidase
HMDKBHPH_00532 1.3e-47 adk 2.7.4.3 F AAA domain
HMDKBHPH_00533 2.1e-80 K acetyltransferase
HMDKBHPH_00534 1.9e-214 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMDKBHPH_00535 2.1e-24 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMDKBHPH_00536 6.6e-139 stp 3.1.3.16 T phosphatase
HMDKBHPH_00537 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HMDKBHPH_00538 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMDKBHPH_00539 9.5e-103 L PFAM Integrase catalytic
HMDKBHPH_00540 8.6e-119 clcA P chloride
HMDKBHPH_00541 1.6e-60 clcA P chloride
HMDKBHPH_00542 4.7e-26 K FCD
HMDKBHPH_00543 3.4e-15 K FCD
HMDKBHPH_00544 1e-44
HMDKBHPH_00545 2.9e-27 D Alpha beta
HMDKBHPH_00546 2.2e-119 D Alpha beta
HMDKBHPH_00547 1.2e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMDKBHPH_00548 3e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMDKBHPH_00549 7.8e-85
HMDKBHPH_00550 1.8e-47
HMDKBHPH_00551 0.0 uup S ABC transporter, ATP-binding protein
HMDKBHPH_00552 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMDKBHPH_00553 1.9e-75 M LysM domain
HMDKBHPH_00554 4.5e-43
HMDKBHPH_00556 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMDKBHPH_00557 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMDKBHPH_00558 4.9e-63 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMDKBHPH_00559 4.1e-69 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMDKBHPH_00560 7.3e-152 S Uncharacterized protein conserved in bacteria (DUF2325)
HMDKBHPH_00561 4.6e-88 C nitroreductase
HMDKBHPH_00562 1.7e-249 yhdP S Transporter associated domain
HMDKBHPH_00563 7.8e-100 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMDKBHPH_00564 0.0 1.3.5.4 C FAD binding domain
HMDKBHPH_00565 6.9e-242 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMDKBHPH_00566 8.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
HMDKBHPH_00567 0.0 clpE O Belongs to the ClpA ClpB family
HMDKBHPH_00568 1.3e-27
HMDKBHPH_00569 8.5e-41 ptsH G phosphocarrier protein HPR
HMDKBHPH_00570 1.3e-116 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMDKBHPH_00571 6.4e-204 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMDKBHPH_00572 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMDKBHPH_00573 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMDKBHPH_00574 8.6e-78 ykoD P ABC transporter, ATP-binding protein
HMDKBHPH_00575 1.2e-144 cbiQ P cobalt transport
HMDKBHPH_00576 1.8e-22
HMDKBHPH_00577 7.9e-71 yeaL S Protein of unknown function (DUF441)
HMDKBHPH_00578 8.2e-24 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HMDKBHPH_00579 6.2e-36 licR 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
HMDKBHPH_00580 0.0 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HMDKBHPH_00581 5e-129 znuB U ABC 3 transport family
HMDKBHPH_00582 1.6e-117 fhuC P ABC transporter
HMDKBHPH_00583 1.4e-148 psaA P Belongs to the bacterial solute-binding protein 9 family
HMDKBHPH_00584 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMDKBHPH_00585 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HMDKBHPH_00586 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMDKBHPH_00587 2.6e-135 fruR K DeoR C terminal sensor domain
HMDKBHPH_00588 3.7e-216 natB CP ABC-2 family transporter protein
HMDKBHPH_00589 1.2e-17
HMDKBHPH_00590 7.2e-83 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HMDKBHPH_00591 4.9e-211 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HMDKBHPH_00592 7.8e-70 S Iron-sulphur cluster biosynthesis
HMDKBHPH_00593 5.8e-192 ybiR P Citrate transporter
HMDKBHPH_00594 9.7e-95 lemA S LemA family
HMDKBHPH_00595 2.2e-157 htpX O Belongs to the peptidase M48B family
HMDKBHPH_00596 7.9e-174 K helix_turn_helix, arabinose operon control protein
HMDKBHPH_00597 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
HMDKBHPH_00598 4.5e-144 ybbH_2 K rpiR family
HMDKBHPH_00599 3.1e-187 S Bacterial protein of unknown function (DUF871)
HMDKBHPH_00600 1.4e-183 yfeW 3.4.16.4 V Beta-lactamase
HMDKBHPH_00601 2.4e-114 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMDKBHPH_00602 2e-227 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMDKBHPH_00603 1.9e-71 S Tetratricopeptide repeat protein
HMDKBHPH_00608 1.1e-24 S HNH endonuclease
HMDKBHPH_00609 1.3e-09
HMDKBHPH_00612 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMDKBHPH_00613 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HMDKBHPH_00614 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDKBHPH_00615 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HMDKBHPH_00616 0.0 mtlR K Mga helix-turn-helix domain
HMDKBHPH_00617 5.3e-80
HMDKBHPH_00618 2e-295 S SLAP domain
HMDKBHPH_00619 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMDKBHPH_00620 1.6e-171 2.7.1.2 GK ROK family
HMDKBHPH_00621 6.6e-44
HMDKBHPH_00622 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDKBHPH_00623 8.9e-10 G Phosphoglycerate mutase family
HMDKBHPH_00624 2.9e-78 G Phosphoglycerate mutase family
HMDKBHPH_00625 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMDKBHPH_00626 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMDKBHPH_00627 2.1e-95 ymfM S Helix-turn-helix domain
HMDKBHPH_00628 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HMDKBHPH_00629 1.9e-236 S Peptidase M16
HMDKBHPH_00630 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HMDKBHPH_00631 3.3e-192 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMDKBHPH_00632 1.5e-190 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMDKBHPH_00633 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
HMDKBHPH_00634 4.9e-111 ybbL S ABC transporter, ATP-binding protein
HMDKBHPH_00635 0.0 S SH3-like domain
HMDKBHPH_00636 8.8e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMDKBHPH_00637 2.1e-171 whiA K May be required for sporulation
HMDKBHPH_00638 2e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMDKBHPH_00639 6.2e-165 rapZ S Displays ATPase and GTPase activities
HMDKBHPH_00640 4.1e-90 S Short repeat of unknown function (DUF308)
HMDKBHPH_00641 3.8e-215 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMDKBHPH_00642 4e-98 rihB 3.2.2.1 F Nucleoside
HMDKBHPH_00643 2.8e-111 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMDKBHPH_00644 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMDKBHPH_00645 2.1e-32 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMDKBHPH_00646 1.1e-209 S SLAP domain
HMDKBHPH_00647 7.1e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMDKBHPH_00648 1.4e-144 E GDSL-like Lipase/Acylhydrolase family
HMDKBHPH_00649 3.4e-21 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMDKBHPH_00650 2.6e-58 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMDKBHPH_00651 1.8e-25 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMDKBHPH_00652 6.4e-162 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HMDKBHPH_00653 2e-106 K Transcriptional regulator, AbiEi antitoxin
HMDKBHPH_00654 6.1e-188 K Periplasmic binding protein-like domain
HMDKBHPH_00655 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMDKBHPH_00656 7e-147 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMDKBHPH_00657 1.4e-16 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMDKBHPH_00658 2.5e-215 sptS 2.7.13.3 T Histidine kinase
HMDKBHPH_00659 1.3e-65 K response regulator
HMDKBHPH_00660 6e-27 K response regulator
HMDKBHPH_00661 1.1e-107 2.7.6.5 T Region found in RelA / SpoT proteins
HMDKBHPH_00662 1.2e-266 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HMDKBHPH_00663 1.5e-263 rafA 3.2.1.22 G alpha-galactosidase
HMDKBHPH_00664 2.4e-196 nusA K Participates in both transcription termination and antitermination
HMDKBHPH_00665 8.8e-47 ylxR K Protein of unknown function (DUF448)
HMDKBHPH_00666 3.2e-47 rplGA J ribosomal protein
HMDKBHPH_00667 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMDKBHPH_00670 2.7e-55 L Phage terminase, small subunit
HMDKBHPH_00671 1.6e-105 tag 3.2.2.20 L glycosylase
HMDKBHPH_00672 3.9e-84
HMDKBHPH_00673 1.6e-271 S Calcineurin-like phosphoesterase
HMDKBHPH_00674 0.0 asnB 6.3.5.4 E Asparagine synthase
HMDKBHPH_00675 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HMDKBHPH_00676 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMDKBHPH_00677 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMDKBHPH_00678 6.2e-103 S Iron-sulfur cluster assembly protein
HMDKBHPH_00679 1.5e-230 XK27_04775 S PAS domain
HMDKBHPH_00680 2.8e-208 yttB EGP Major facilitator Superfamily
HMDKBHPH_00681 6.4e-90 alkD L DNA alkylation repair enzyme
HMDKBHPH_00682 1.6e-173 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMDKBHPH_00683 1.2e-99 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMDKBHPH_00684 1.1e-127 K UTRA domain
HMDKBHPH_00685 1.3e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMDKBHPH_00686 1.7e-49 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HMDKBHPH_00687 6.7e-184 G Bacterial extracellular solute-binding protein
HMDKBHPH_00688 5.7e-18
HMDKBHPH_00689 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HMDKBHPH_00690 3.1e-95 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMDKBHPH_00691 6.9e-133 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HMDKBHPH_00692 9.2e-89 ypmB S Protein conserved in bacteria
HMDKBHPH_00693 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMDKBHPH_00694 3.5e-29
HMDKBHPH_00695 2.9e-73 yniG EGP Major facilitator Superfamily
HMDKBHPH_00696 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HMDKBHPH_00697 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMDKBHPH_00698 8e-163 yihY S Belongs to the UPF0761 family
HMDKBHPH_00699 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
HMDKBHPH_00700 4.1e-80 fld C Flavodoxin
HMDKBHPH_00701 1.9e-84 gtcA S Teichoic acid glycosylation protein
HMDKBHPH_00702 2.3e-32 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMDKBHPH_00703 9.5e-29 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMDKBHPH_00704 3.6e-160 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HMDKBHPH_00705 8.6e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMDKBHPH_00706 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMDKBHPH_00707 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMDKBHPH_00708 5.5e-31 ftsL D Cell division protein FtsL
HMDKBHPH_00709 5.4e-16 sufD O FeS assembly protein SufD
HMDKBHPH_00710 1.7e-176 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMDKBHPH_00711 2.7e-58 nifU C SUF system FeS assembly protein, NifU family
HMDKBHPH_00712 0.0 1.3.5.4 C FAD binding domain
HMDKBHPH_00713 2.8e-230 potE E amino acid
HMDKBHPH_00714 0.0 L AAA domain
HMDKBHPH_00715 1.5e-230 yhaO L Ser Thr phosphatase family protein
HMDKBHPH_00716 7.2e-56 yheA S Belongs to the UPF0342 family
HMDKBHPH_00717 6.4e-54 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMDKBHPH_00718 1.9e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMDKBHPH_00719 1.5e-65 yqhL P Rhodanese-like protein
HMDKBHPH_00720 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HMDKBHPH_00721 5.3e-40 gluP 3.4.21.105 S Rhomboid family
HMDKBHPH_00722 2.6e-267 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMDKBHPH_00723 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
HMDKBHPH_00725 1.6e-08
HMDKBHPH_00726 1.4e-83 K FR47-like protein
HMDKBHPH_00727 7e-26 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMDKBHPH_00728 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMDKBHPH_00729 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMDKBHPH_00730 4.7e-132 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMDKBHPH_00731 2.2e-208 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMDKBHPH_00732 6.5e-125 S Protein of unknown function (DUF554)
HMDKBHPH_00733 8.2e-61
HMDKBHPH_00734 5.6e-19
HMDKBHPH_00735 1.1e-101 rimL J Acetyltransferase (GNAT) domain
HMDKBHPH_00736 8.3e-58
HMDKBHPH_00737 8.9e-292 S ABC transporter
HMDKBHPH_00738 2.4e-136 thrE S Putative threonine/serine exporter
HMDKBHPH_00739 1.1e-83 S Threonine/Serine exporter, ThrE
HMDKBHPH_00740 9.1e-112 yvpB S Peptidase_C39 like family
HMDKBHPH_00741 2.5e-68
HMDKBHPH_00742 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMDKBHPH_00743 5.5e-77 nrdI F NrdI Flavodoxin like
HMDKBHPH_00744 2.3e-223 tnpB L Putative transposase DNA-binding domain
HMDKBHPH_00745 3.3e-112
HMDKBHPH_00746 1.9e-278 S O-antigen ligase like membrane protein
HMDKBHPH_00747 3.9e-42
HMDKBHPH_00748 7.7e-89 gmk2 2.7.4.8 F Guanylate kinase homologues.
HMDKBHPH_00749 2e-89 M NlpC/P60 family
HMDKBHPH_00750 1.4e-136 M NlpC P60 family protein
HMDKBHPH_00751 2.6e-118 M NlpC/P60 family
HMDKBHPH_00752 3.5e-41
HMDKBHPH_00753 7.1e-144 S Cysteine-rich secretory protein family
HMDKBHPH_00754 2.8e-123 skfE V ATPases associated with a variety of cellular activities
HMDKBHPH_00755 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
HMDKBHPH_00756 2.1e-76 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMDKBHPH_00757 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMDKBHPH_00758 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMDKBHPH_00759 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
HMDKBHPH_00760 1.7e-37 L An automated process has identified a potential problem with this gene model
HMDKBHPH_00761 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMDKBHPH_00762 2.3e-90 ecsA V ABC transporter, ATP-binding protein
HMDKBHPH_00763 1.5e-164 ecsB U ABC transporter
HMDKBHPH_00764 4.1e-73 vanZ V VanZ like family
HMDKBHPH_00765 5.9e-17 vanZ V VanZ like family
HMDKBHPH_00766 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMDKBHPH_00767 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HMDKBHPH_00768 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMDKBHPH_00769 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
HMDKBHPH_00770 1.2e-190 S Putative peptidoglycan binding domain
HMDKBHPH_00771 4e-16
HMDKBHPH_00772 7.9e-92 liaI S membrane
HMDKBHPH_00773 1.7e-70 XK27_02470 K LytTr DNA-binding domain
HMDKBHPH_00775 4.2e-232 S SLAP domain
HMDKBHPH_00776 5.9e-09
HMDKBHPH_00777 4.4e-43
HMDKBHPH_00778 4.3e-65 2.7.1.191 G PTS system fructose IIA component
HMDKBHPH_00779 1.8e-128 3.6.3.8 P P-type ATPase
HMDKBHPH_00781 2.9e-44
HMDKBHPH_00782 1.5e-94 S Protein of unknown function (DUF3990)
HMDKBHPH_00783 2e-169 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HMDKBHPH_00784 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
HMDKBHPH_00785 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMDKBHPH_00786 9.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMDKBHPH_00787 1.5e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HMDKBHPH_00788 9.1e-50 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMDKBHPH_00789 2.4e-09 lacS G Transporter
HMDKBHPH_00790 3.2e-165 lacR K Transcriptional regulator
HMDKBHPH_00792 1.1e-164 natA S ABC transporter, ATP-binding protein
HMDKBHPH_00793 1.7e-67
HMDKBHPH_00794 2e-23
HMDKBHPH_00795 8.2e-31 yozG K Transcriptional regulator
HMDKBHPH_00796 3.7e-83
HMDKBHPH_00797 3e-21
HMDKBHPH_00801 2.2e-129 blpT
HMDKBHPH_00802 1.4e-107 M Transport protein ComB
HMDKBHPH_00803 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMDKBHPH_00804 1.5e-128 K LytTr DNA-binding domain
HMDKBHPH_00805 4.4e-138 2.7.13.3 T GHKL domain
HMDKBHPH_00806 1.2e-16
HMDKBHPH_00807 2.1e-255 S Archaea bacterial proteins of unknown function
HMDKBHPH_00808 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HMDKBHPH_00809 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HMDKBHPH_00810 1e-24
HMDKBHPH_00811 2.1e-25
HMDKBHPH_00812 2.5e-33
HMDKBHPH_00813 1.4e-53 S Enterocin A Immunity
HMDKBHPH_00814 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMDKBHPH_00815 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMDKBHPH_00816 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HMDKBHPH_00817 9.6e-121 K response regulator
HMDKBHPH_00818 0.0 V ABC transporter
HMDKBHPH_00819 4.2e-144 V ABC transporter, ATP-binding protein
HMDKBHPH_00820 1.2e-145 V ABC transporter, ATP-binding protein
HMDKBHPH_00821 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
HMDKBHPH_00822 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMDKBHPH_00823 2.8e-44 yyzM S Bacterial protein of unknown function (DUF951)
HMDKBHPH_00824 6.1e-152 spo0J K Belongs to the ParB family
HMDKBHPH_00825 3.4e-138 soj D Sporulation initiation inhibitor
HMDKBHPH_00826 5e-148 noc K Belongs to the ParB family
HMDKBHPH_00827 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HMDKBHPH_00828 3e-53 cvpA S Colicin V production protein
HMDKBHPH_00829 5.2e-178 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMDKBHPH_00830 6e-151 3.1.3.48 T Tyrosine phosphatase family
HMDKBHPH_00831 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HMDKBHPH_00832 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HMDKBHPH_00833 3.7e-111 K WHG domain
HMDKBHPH_00834 5.7e-32
HMDKBHPH_00835 5.9e-45
HMDKBHPH_00836 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMDKBHPH_00838 2.1e-45 S PFAM Archaeal ATPase
HMDKBHPH_00839 7.3e-74
HMDKBHPH_00840 0.0 kup P Transport of potassium into the cell
HMDKBHPH_00841 0.0 pepO 3.4.24.71 O Peptidase family M13
HMDKBHPH_00842 9.1e-76 sip L Belongs to the 'phage' integrase family
HMDKBHPH_00845 9.8e-18 K Transcriptional
HMDKBHPH_00847 2.3e-113 K BRO family, N-terminal domain
HMDKBHPH_00849 4.3e-07
HMDKBHPH_00853 5.3e-68 S Protein of unknown function (DUF1351)
HMDKBHPH_00854 6.3e-77 S ERF superfamily
HMDKBHPH_00855 1.1e-64 L DnaD domain protein
HMDKBHPH_00860 8.2e-10
HMDKBHPH_00863 3.4e-08
HMDKBHPH_00864 7.4e-49 S ASCH domain
HMDKBHPH_00866 2.6e-86 L transposase activity
HMDKBHPH_00867 8.2e-222 S Terminase RNAseH like domain
HMDKBHPH_00868 6.4e-216 S Phage portal protein, SPP1 Gp6-like
HMDKBHPH_00869 2.2e-165 S Phage minor capsid protein 2
HMDKBHPH_00871 4.6e-37 S Phage minor structural protein GP20
HMDKBHPH_00872 4.6e-154 gpG
HMDKBHPH_00873 1.4e-44
HMDKBHPH_00874 1.6e-39 S Minor capsid protein
HMDKBHPH_00875 4e-31 S Minor capsid protein
HMDKBHPH_00876 3e-51 S Minor capsid protein from bacteriophage
HMDKBHPH_00877 7e-25 N domain, Protein
HMDKBHPH_00878 2.4e-56 2.4.2.3 F Phosphorylase superfamily
HMDKBHPH_00879 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HMDKBHPH_00880 1e-125 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMDKBHPH_00881 1.3e-40 yajC U Preprotein translocase
HMDKBHPH_00882 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMDKBHPH_00883 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMDKBHPH_00884 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMDKBHPH_00885 4.7e-228 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMDKBHPH_00886 7.1e-294 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMDKBHPH_00889 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMDKBHPH_00890 2.7e-300 S Predicted membrane protein (DUF2207)
HMDKBHPH_00891 1.3e-157 cinI S Serine hydrolase (FSH1)
HMDKBHPH_00892 1.9e-204 M Glycosyl hydrolases family 25
HMDKBHPH_00894 2.9e-178 I Carboxylesterase family
HMDKBHPH_00895 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HMDKBHPH_00897 4.8e-84 ydcK S Belongs to the SprT family
HMDKBHPH_00898 7e-74 M Glycosyltransferase sugar-binding region containing DXD motif
HMDKBHPH_00899 1.1e-172 patB 4.4.1.8 E Aminotransferase, class I
HMDKBHPH_00900 7.3e-126 S Alpha/beta hydrolase family
HMDKBHPH_00901 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
HMDKBHPH_00902 7.5e-140 ypuA S Protein of unknown function (DUF1002)
HMDKBHPH_00903 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMDKBHPH_00904 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
HMDKBHPH_00905 4.6e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMDKBHPH_00906 9.3e-86
HMDKBHPH_00907 1.3e-141 yfeO P Voltage gated chloride channel
HMDKBHPH_00908 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
HMDKBHPH_00909 1.4e-51
HMDKBHPH_00910 2.1e-42
HMDKBHPH_00911 3e-176 S membrane
HMDKBHPH_00912 6.7e-41 S cog cog0433
HMDKBHPH_00913 4.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HMDKBHPH_00914 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HMDKBHPH_00915 2.2e-68 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMDKBHPH_00917 1.7e-29 S Predicted membrane protein (DUF2335)
HMDKBHPH_00919 1.5e-74 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMDKBHPH_00920 2.2e-135 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMDKBHPH_00921 5.1e-181 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMDKBHPH_00922 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMDKBHPH_00923 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HMDKBHPH_00924 0.0 pacL 3.6.3.8 P P-type ATPase
HMDKBHPH_00925 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMDKBHPH_00926 3e-257 epsU S Polysaccharide biosynthesis protein
HMDKBHPH_00927 3.9e-47 M Glycosyltransferase sugar-binding region containing DXD motif
HMDKBHPH_00928 2.7e-51
HMDKBHPH_00929 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
HMDKBHPH_00930 3.3e-44
HMDKBHPH_00931 5.4e-183 S AAA domain
HMDKBHPH_00932 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMDKBHPH_00933 1.4e-23
HMDKBHPH_00934 7.3e-161 czcD P cation diffusion facilitator family transporter
HMDKBHPH_00935 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
HMDKBHPH_00936 6.6e-131 S membrane transporter protein
HMDKBHPH_00937 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMDKBHPH_00938 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HMDKBHPH_00939 1.2e-49 S Protein of unknown function (DUF3021)
HMDKBHPH_00940 2.8e-65 K LytTr DNA-binding domain
HMDKBHPH_00941 1.2e-10
HMDKBHPH_00942 1.8e-28 qmcA O prohibitin homologues
HMDKBHPH_00943 1.9e-199 purD 6.3.4.13 F Belongs to the GARS family
HMDKBHPH_00944 7.1e-63 M LysM domain protein
HMDKBHPH_00945 2.2e-37 S aldo-keto reductase (NADP) activity
HMDKBHPH_00946 3.1e-64 C Aldo keto reductase
HMDKBHPH_00947 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
HMDKBHPH_00948 1.1e-71 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMDKBHPH_00949 7.8e-248 lctP C L-lactate permease
HMDKBHPH_00950 1.7e-28 mloB K Putative ATP-dependent DNA helicase recG C-terminal
HMDKBHPH_00952 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMDKBHPH_00953 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HMDKBHPH_00954 5.2e-110 yjbK S CYTH
HMDKBHPH_00955 4.6e-114 yjbH Q Thioredoxin
HMDKBHPH_00956 4e-13 coiA 3.6.4.12 S Competence protein
HMDKBHPH_00957 4.3e-76 coiA 3.6.4.12 S Competence protein
HMDKBHPH_00958 4.5e-112 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HMDKBHPH_00959 3.3e-147 glvR K Helix-turn-helix domain, rpiR family
HMDKBHPH_00960 1.6e-80
HMDKBHPH_00961 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMDKBHPH_00962 2.1e-39
HMDKBHPH_00963 1.1e-101 3.6.1.27 I Acid phosphatase homologues
HMDKBHPH_00964 2.9e-116 plsC 2.3.1.51 I Acyltransferase
HMDKBHPH_00965 8.9e-195 yabB 2.1.1.223 L Methyltransferase small domain
HMDKBHPH_00966 4.9e-44 rpsB J Belongs to the universal ribosomal protein uS2 family
HMDKBHPH_00967 1.6e-77 rpsB J Belongs to the universal ribosomal protein uS2 family
HMDKBHPH_00968 2.5e-74 endA F DNA RNA non-specific endonuclease
HMDKBHPH_00969 1.6e-282 pipD E Dipeptidase
HMDKBHPH_00970 9.3e-203 malK P ATPases associated with a variety of cellular activities
HMDKBHPH_00971 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
HMDKBHPH_00972 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HMDKBHPH_00973 2.4e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HMDKBHPH_00974 5.1e-240 G Bacterial extracellular solute-binding protein
HMDKBHPH_00975 1.8e-154 corA P CorA-like Mg2+ transporter protein
HMDKBHPH_00976 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
HMDKBHPH_00977 5.1e-99 yobS K Bacterial regulatory proteins, tetR family
HMDKBHPH_00978 0.0 ydgH S MMPL family
HMDKBHPH_00979 3.4e-107
HMDKBHPH_00980 8.3e-41
HMDKBHPH_00981 0.0 XK27_08315 M Sulfatase
HMDKBHPH_00982 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMDKBHPH_00983 5.2e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMDKBHPH_00984 1.4e-98 G Aldose 1-epimerase
HMDKBHPH_00985 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMDKBHPH_00986 2.1e-116
HMDKBHPH_00987 2.1e-130
HMDKBHPH_00988 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
HMDKBHPH_00989 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMDKBHPH_00990 1.9e-113 yjbQ P TrkA C-terminal domain protein
HMDKBHPH_00991 8.8e-177 yjbQ P TrkA C-terminal domain protein
HMDKBHPH_00992 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HMDKBHPH_00993 3.5e-214 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMDKBHPH_00995 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMDKBHPH_00996 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
HMDKBHPH_00997 1.6e-21
HMDKBHPH_00998 9.4e-76 comGF U Putative Competence protein ComGF
HMDKBHPH_00999 8.6e-41
HMDKBHPH_01000 7.4e-71
HMDKBHPH_01001 3.1e-43 comGC U competence protein ComGC
HMDKBHPH_01002 1.7e-171 comGB NU type II secretion system
HMDKBHPH_01003 1.7e-179 comGA NU Type II IV secretion system protein
HMDKBHPH_01004 1.8e-40 yebC K Transcriptional regulatory protein
HMDKBHPH_01005 1.8e-38 C FMN_bind
HMDKBHPH_01006 3.9e-82
HMDKBHPH_01007 1.9e-83 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HMDKBHPH_01009 8.7e-218 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMDKBHPH_01010 7e-246 qacA EGP Major facilitator Superfamily
HMDKBHPH_01011 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMDKBHPH_01012 1.8e-113 trsE S COG0433 Predicted ATPase
HMDKBHPH_01013 7.2e-33 M Peptidase family M23
HMDKBHPH_01016 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
HMDKBHPH_01022 5.8e-52 S COG0790 FOG TPR repeat, SEL1 subfamily
HMDKBHPH_01023 7.2e-38 L Protein of unknown function (DUF3991)
HMDKBHPH_01024 1.2e-111 S Fic/DOC family
HMDKBHPH_01026 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMDKBHPH_01027 2.8e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMDKBHPH_01028 3.6e-20 arsC 1.20.4.1 P Belongs to the ArsC family
HMDKBHPH_01029 7e-276 V ABC-type multidrug transport system, ATPase and permease components
HMDKBHPH_01030 6.3e-108 V ABC-type multidrug transport system, ATPase and permease components
HMDKBHPH_01031 3.3e-161 V ABC-type multidrug transport system, ATPase and permease components
HMDKBHPH_01032 4e-113 S haloacid dehalogenase-like hydrolase
HMDKBHPH_01033 2.6e-52
HMDKBHPH_01034 1.9e-37
HMDKBHPH_01035 2.3e-65 S Alpha beta hydrolase
HMDKBHPH_01036 1.1e-36 S Alpha beta hydrolase
HMDKBHPH_01037 1.2e-30 copZ C Heavy-metal-associated domain
HMDKBHPH_01038 2.9e-284 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HMDKBHPH_01039 1.9e-30 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HMDKBHPH_01040 7e-25 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HMDKBHPH_01041 1.1e-20 L Psort location Cytoplasmic, score
HMDKBHPH_01049 2.3e-10 K Helix-turn-helix XRE-family like proteins
HMDKBHPH_01050 6.2e-74 3.4.21.88 K Peptidase S24-like
HMDKBHPH_01051 2.5e-30 S Hypothetical protein (DUF2513)
HMDKBHPH_01054 1.6e-180 V Abi-like protein
HMDKBHPH_01055 3.1e-122 L Belongs to the 'phage' integrase family
HMDKBHPH_01056 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMDKBHPH_01057 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMDKBHPH_01058 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HMDKBHPH_01059 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMDKBHPH_01060 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMDKBHPH_01061 4.2e-139 cdsA 2.7.7.41 I Belongs to the CDS family
HMDKBHPH_01062 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMDKBHPH_01063 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMDKBHPH_01064 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMDKBHPH_01065 1.3e-16 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMDKBHPH_01066 9.4e-84 smc D Required for chromosome condensation and partitioning
HMDKBHPH_01067 5.1e-122 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMDKBHPH_01068 1.7e-307 oppA E ABC transporter substrate-binding protein
HMDKBHPH_01069 3.1e-240 oppA E ABC transporter substrate-binding protein
HMDKBHPH_01070 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
HMDKBHPH_01071 1.9e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMDKBHPH_01072 2.6e-95 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMDKBHPH_01073 1.1e-29 K Helix-turn-helix domain
HMDKBHPH_01074 1.5e-26 S Domain of unknown function (DUF771)
HMDKBHPH_01082 2.1e-10
HMDKBHPH_01083 3.3e-11 S Single-strand binding protein family
HMDKBHPH_01089 1.9e-21 S SLAP domain
HMDKBHPH_01090 1.4e-24 srtA 3.4.22.70 M sortase family
HMDKBHPH_01092 1.9e-35 trsE S COG0433 Predicted ATPase
HMDKBHPH_01093 8.4e-15
HMDKBHPH_01095 2.3e-32 I mechanosensitive ion channel activity
HMDKBHPH_01096 2.4e-141 U TraM recognition site of TraD and TraG
HMDKBHPH_01100 4.1e-32 M domain protein
HMDKBHPH_01101 9.3e-07 M domain protein
HMDKBHPH_01102 6.5e-15 S SLAP domain
HMDKBHPH_01103 2.5e-11 M domain protein
HMDKBHPH_01104 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMDKBHPH_01105 1e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMDKBHPH_01106 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMDKBHPH_01107 1e-147 tatD L hydrolase, TatD family
HMDKBHPH_01108 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMDKBHPH_01109 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMDKBHPH_01110 4.5e-39 veg S Biofilm formation stimulator VEG
HMDKBHPH_01111 1.1e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HMDKBHPH_01112 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMDKBHPH_01113 6e-114 S Sucrose-6F-phosphate phosphohydrolase
HMDKBHPH_01114 6.3e-177 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMDKBHPH_01115 8.3e-143 licT K CAT RNA binding domain
HMDKBHPH_01116 3.1e-136 glcR K DeoR C terminal sensor domain
HMDKBHPH_01117 2.5e-59 S Enterocin A Immunity
HMDKBHPH_01118 1e-153 S hydrolase
HMDKBHPH_01119 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
HMDKBHPH_01120 9.1e-175 rihB 3.2.2.1 F Nucleoside
HMDKBHPH_01121 0.0 kup P Transport of potassium into the cell
HMDKBHPH_01122 7.2e-124 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMDKBHPH_01123 5.4e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMDKBHPH_01124 1.3e-161 2.7.7.12 C Domain of unknown function (DUF4931)
HMDKBHPH_01125 8e-178 E ABC transporter, substratebinding protein
HMDKBHPH_01126 3.7e-66 K Helix-turn-helix domain, rpiR family
HMDKBHPH_01127 7.1e-98 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HMDKBHPH_01128 8.9e-101 treR K UTRA
HMDKBHPH_01129 1.6e-76 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMDKBHPH_01130 1.3e-51 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMDKBHPH_01131 4.2e-170 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMDKBHPH_01132 1.2e-17 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMDKBHPH_01133 2.4e-16 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HMDKBHPH_01134 5.6e-179 S PFAM Archaeal ATPase
HMDKBHPH_01135 1.8e-193 I transferase activity, transferring acyl groups other than amino-acyl groups
HMDKBHPH_01136 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMDKBHPH_01137 2e-155 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
HMDKBHPH_01138 1.7e-99 J Acetyltransferase (GNAT) domain
HMDKBHPH_01139 1.8e-237 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMDKBHPH_01140 1.1e-19 UW LPXTG-motif cell wall anchor domain protein
HMDKBHPH_01141 9.6e-45 UW LPXTG-motif cell wall anchor domain protein
HMDKBHPH_01142 1.7e-104 UW LPXTG-motif cell wall anchor domain protein
HMDKBHPH_01143 3e-15 sufB O assembly protein SufB
HMDKBHPH_01144 3.9e-38 sufB O assembly protein SufB
HMDKBHPH_01145 2.4e-45 yitW S Iron-sulfur cluster assembly protein
HMDKBHPH_01146 5e-247 mntH P H( )-stimulated, divalent metal cation uptake system
HMDKBHPH_01147 2.2e-154 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMDKBHPH_01148 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMDKBHPH_01149 2e-30 ywzB S Protein of unknown function (DUF1146)
HMDKBHPH_01150 5.1e-57 mbl D Cell shape determining protein MreB Mrl
HMDKBHPH_01151 2.6e-89 mbl D Cell shape determining protein MreB Mrl
HMDKBHPH_01152 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HMDKBHPH_01153 3.3e-33 S Protein of unknown function (DUF2969)
HMDKBHPH_01154 3.1e-215 rodA D Belongs to the SEDS family
HMDKBHPH_01155 4.5e-68 S Domain of unknown function (DUF1934)
HMDKBHPH_01156 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMDKBHPH_01157 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMDKBHPH_01158 5.4e-56 XK27_04120 S Putative amino acid metabolism
HMDKBHPH_01159 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
HMDKBHPH_01160 1.1e-153 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMDKBHPH_01161 5.2e-68 L haloacid dehalogenase-like hydrolase
HMDKBHPH_01162 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HMDKBHPH_01163 2.1e-128 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HMDKBHPH_01164 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HMDKBHPH_01165 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HMDKBHPH_01166 1.3e-231 ulaA S PTS system sugar-specific permease component
HMDKBHPH_01167 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMDKBHPH_01168 8.1e-175 ulaG S Beta-lactamase superfamily domain
HMDKBHPH_01169 1.9e-74 rfbP M Bacterial sugar transferase
HMDKBHPH_01170 3.7e-145 ywqE 3.1.3.48 GM PHP domain protein
HMDKBHPH_01171 5.8e-122 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HMDKBHPH_01172 3.6e-144 epsB M biosynthesis protein
HMDKBHPH_01173 1.7e-177 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMDKBHPH_01174 5.2e-29 M Phage tail tape measure protein TP901
HMDKBHPH_01176 2.9e-09
HMDKBHPH_01177 9.3e-29
HMDKBHPH_01178 3.5e-103 Z012_02110 S Protein of unknown function (DUF3383)
HMDKBHPH_01179 4.3e-31
HMDKBHPH_01180 1.6e-25
HMDKBHPH_01181 1e-29
HMDKBHPH_01182 9.2e-20 S Protein of unknown function (DUF4054)
HMDKBHPH_01183 2.4e-93 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HMDKBHPH_01184 4.1e-34
HMDKBHPH_01185 1.6e-57 S Uncharacterized protein conserved in bacteria (DUF2213)
HMDKBHPH_01186 5e-12 S Lysin motif
HMDKBHPH_01187 1.3e-47 S Phage Mu protein F like protein
HMDKBHPH_01188 6.2e-135 S Protein of unknown function (DUF1073)
HMDKBHPH_01189 1.1e-201 S Terminase-like family
HMDKBHPH_01190 3e-19 ps333 L Terminase small subunit
HMDKBHPH_01193 3.3e-09 arpU S Phage transcriptional regulator, ArpU family
HMDKBHPH_01196 3.8e-219 XK27_11280 S Psort location CytoplasmicMembrane, score
HMDKBHPH_01206 5.8e-20 L Psort location Cytoplasmic, score
HMDKBHPH_01207 2.5e-43 S Protein of unknown function (DUF1071)
HMDKBHPH_01209 7.7e-48
HMDKBHPH_01212 6.8e-08
HMDKBHPH_01214 2.3e-88 S AntA/AntB antirepressor
HMDKBHPH_01216 3.7e-13
HMDKBHPH_01217 3.1e-12
HMDKBHPH_01218 3.7e-18 ps115 K sequence-specific DNA binding
HMDKBHPH_01219 3e-14 S Pfam:Peptidase_M78
HMDKBHPH_01220 1.2e-54 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMDKBHPH_01221 7.5e-12
HMDKBHPH_01225 2.8e-176 sip L Belongs to the 'phage' integrase family
HMDKBHPH_01226 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMDKBHPH_01227 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
HMDKBHPH_01228 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMDKBHPH_01229 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMDKBHPH_01230 2.8e-157 pstS P Phosphate
HMDKBHPH_01231 4.3e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HMDKBHPH_01232 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
HMDKBHPH_01233 3e-38 ynzC S UPF0291 protein
HMDKBHPH_01234 2.4e-50 L RelB antitoxin
HMDKBHPH_01235 1.6e-18
HMDKBHPH_01236 1.7e-192 S Bacteriocin helveticin-J
HMDKBHPH_01237 1.2e-157 M Peptidase family M1 domain
HMDKBHPH_01238 1.4e-83 L Resolvase, N-terminal
HMDKBHPH_01239 1.7e-84 L Putative transposase DNA-binding domain
HMDKBHPH_01240 7.4e-74 L Putative transposase DNA-binding domain
HMDKBHPH_01241 8.4e-171 S SLAP domain
HMDKBHPH_01242 4.9e-45 mepA V MATE efflux family protein
HMDKBHPH_01243 7.1e-173 mepA V MATE efflux family protein
HMDKBHPH_01244 6.1e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMDKBHPH_01245 3.7e-185
HMDKBHPH_01246 6.5e-33 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMDKBHPH_01247 1.4e-71 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMDKBHPH_01248 4e-54 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HMDKBHPH_01249 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMDKBHPH_01250 7.9e-99 M ErfK YbiS YcfS YnhG
HMDKBHPH_01251 2.2e-48 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMDKBHPH_01252 3.5e-71 yqeY S YqeY-like protein
HMDKBHPH_01253 9.5e-175 phoH T phosphate starvation-inducible protein PhoH
HMDKBHPH_01254 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMDKBHPH_01255 4.1e-81 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMDKBHPH_01256 6.7e-37
HMDKBHPH_01257 1.4e-101 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HMDKBHPH_01258 5.2e-08
HMDKBHPH_01259 3e-89 ntd 2.4.2.6 F Nucleoside
HMDKBHPH_01260 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMDKBHPH_01261 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HMDKBHPH_01262 8.8e-84 uspA T universal stress protein
HMDKBHPH_01264 1.2e-161 phnD P Phosphonate ABC transporter
HMDKBHPH_01265 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HMDKBHPH_01266 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HMDKBHPH_01267 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HMDKBHPH_01268 8e-72 S SLAP domain
HMDKBHPH_01269 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMDKBHPH_01271 1.4e-21 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMDKBHPH_01272 1.1e-25
HMDKBHPH_01273 1.2e-77 K DNA-templated transcription, initiation
HMDKBHPH_01274 5.3e-41
HMDKBHPH_01276 1.9e-124 S SLAP domain
HMDKBHPH_01277 4.5e-49 S Fic/DOC family
HMDKBHPH_01278 2.8e-08 S Fic/DOC family
HMDKBHPH_01279 3.1e-278
HMDKBHPH_01280 7.9e-17
HMDKBHPH_01281 3.2e-97 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMDKBHPH_01282 1.5e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDKBHPH_01284 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMDKBHPH_01285 7.3e-21 hicA S HicA toxin of bacterial toxin-antitoxin,
HMDKBHPH_01286 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMDKBHPH_01287 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMDKBHPH_01288 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMDKBHPH_01291 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HMDKBHPH_01292 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
HMDKBHPH_01293 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HMDKBHPH_01294 5.7e-106 2.4.1.58 GT8 M family 8
HMDKBHPH_01295 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMDKBHPH_01296 9.6e-55 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMDKBHPH_01297 2.9e-176 msmX P Belongs to the ABC transporter superfamily
HMDKBHPH_01298 1.8e-210 malE G Bacterial extracellular solute-binding protein
HMDKBHPH_01299 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
HMDKBHPH_01300 3.3e-147 malG P ABC transporter permease
HMDKBHPH_01301 1.5e-59 K Helix-turn-helix XRE-family like proteins
HMDKBHPH_01304 1.6e-28
HMDKBHPH_01306 6.7e-88 ymdB S Macro domain protein
HMDKBHPH_01307 4.3e-212 mdtG EGP Major facilitator Superfamily
HMDKBHPH_01308 7.4e-175
HMDKBHPH_01309 2.8e-47 lysM M LysM domain
HMDKBHPH_01310 0.0 pepN 3.4.11.2 E aminopeptidase
HMDKBHPH_01311 4.8e-61 yveB 2.7.4.29 I PAP2 superfamily
HMDKBHPH_01312 1.1e-12 yveB 2.7.4.29 I Membrane-associated phospholipid phosphatase
HMDKBHPH_01313 3.2e-26 xerC L Phage integrase, N-terminal SAM-like domain
HMDKBHPH_01314 1.7e-83 pstS P Phosphate
HMDKBHPH_01315 9.2e-44 pstS P Phosphate
HMDKBHPH_01316 6.2e-67 pstC P probably responsible for the translocation of the substrate across the membrane
HMDKBHPH_01317 1.3e-64 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMDKBHPH_01318 6.8e-20 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMDKBHPH_01319 7.9e-64 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMDKBHPH_01320 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMDKBHPH_01321 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMDKBHPH_01322 5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMDKBHPH_01323 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMDKBHPH_01324 3.5e-75
HMDKBHPH_01325 2.3e-181 M CHAP domain
HMDKBHPH_01326 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HMDKBHPH_01327 1.8e-289 scrB 3.2.1.26 GH32 G invertase
HMDKBHPH_01328 6.7e-76 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMDKBHPH_01329 2.8e-125 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMDKBHPH_01330 1.4e-107 yisY 1.11.1.10 S Alpha/beta hydrolase family
HMDKBHPH_01331 3.7e-33 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMDKBHPH_01332 8.8e-58 S Peptidase propeptide and YPEB domain
HMDKBHPH_01333 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMDKBHPH_01334 7.4e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HMDKBHPH_01335 7.1e-98 E GDSL-like Lipase/Acylhydrolase
HMDKBHPH_01336 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
HMDKBHPH_01337 1.6e-143 aatB ET ABC transporter substrate-binding protein
HMDKBHPH_01338 1e-105 glnQ 3.6.3.21 E ABC transporter
HMDKBHPH_01339 1.5e-107 glnP P ABC transporter permease
HMDKBHPH_01340 0.0 helD 3.6.4.12 L DNA helicase
HMDKBHPH_01341 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMDKBHPH_01342 3.2e-181 ccpA K catabolite control protein A
HMDKBHPH_01343 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMDKBHPH_01344 4.3e-55
HMDKBHPH_01345 9.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMDKBHPH_01346 1.7e-105 yutD S Protein of unknown function (DUF1027)
HMDKBHPH_01347 6.9e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMDKBHPH_01348 3.7e-100 S Protein of unknown function (DUF1461)
HMDKBHPH_01349 2.6e-115 dedA S SNARE-like domain protein
HMDKBHPH_01350 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HMDKBHPH_01351 1.1e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMDKBHPH_01352 4.9e-63 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMDKBHPH_01353 8.4e-40 S Phage minor structural protein
HMDKBHPH_01355 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
HMDKBHPH_01356 9.6e-78 P Cobalt transport protein
HMDKBHPH_01357 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HMDKBHPH_01358 6.5e-91 G Peptidase_C39 like family
HMDKBHPH_01359 2.8e-162 M NlpC/P60 family
HMDKBHPH_01360 8.4e-25 G Peptidase_C39 like family
HMDKBHPH_01361 3.2e-124
HMDKBHPH_01362 2.2e-240 S response to antibiotic
HMDKBHPH_01363 1.1e-43 pgm3 G Phosphoglycerate mutase family
HMDKBHPH_01364 8.9e-57 hsdM 2.1.1.72 V type I restriction-modification system
HMDKBHPH_01365 3.4e-42 S RloB-like protein
HMDKBHPH_01366 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
HMDKBHPH_01367 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HMDKBHPH_01368 1.4e-12
HMDKBHPH_01369 1.5e-169
HMDKBHPH_01370 2.1e-128 glnA 6.3.1.2 E glutamine synthetase
HMDKBHPH_01371 2.3e-87 S Protein of unknown function (DUF805)
HMDKBHPH_01372 5.6e-68 O OsmC-like protein
HMDKBHPH_01373 1.4e-142 EGP Major facilitator Superfamily
HMDKBHPH_01374 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMDKBHPH_01375 1.3e-168 dnaI L Primosomal protein DnaI
HMDKBHPH_01376 8.6e-251 dnaB L Replication initiation and membrane attachment
HMDKBHPH_01377 3.9e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMDKBHPH_01378 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMDKBHPH_01379 9.4e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMDKBHPH_01380 3.3e-98 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMDKBHPH_01381 3.1e-47 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMDKBHPH_01382 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HMDKBHPH_01383 1.7e-34
HMDKBHPH_01384 4.2e-95 sigH K Belongs to the sigma-70 factor family
HMDKBHPH_01385 6.6e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMDKBHPH_01386 6.7e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMDKBHPH_01387 3.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMDKBHPH_01388 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMDKBHPH_01389 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMDKBHPH_01390 2.6e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HMDKBHPH_01391 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMDKBHPH_01392 1.3e-38 S RelB antitoxin
HMDKBHPH_01393 2.9e-19 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HMDKBHPH_01394 7.9e-65 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMDKBHPH_01395 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMDKBHPH_01396 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMDKBHPH_01397 1.4e-79 fabK 1.3.1.9 S Nitronate monooxygenase
HMDKBHPH_01398 6.1e-111 crt 4.2.1.17 I Enoyl-CoA hydratase/isomerase
HMDKBHPH_01399 1.1e-20 glpF G Major intrinsic protein
HMDKBHPH_01400 3.5e-155 brnQ U Component of the transport system for branched-chain amino acids
HMDKBHPH_01401 5.7e-80 brnQ U Component of the transport system for branched-chain amino acids
HMDKBHPH_01402 1.3e-134 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMDKBHPH_01403 2.4e-126 potB P ABC transporter permease
HMDKBHPH_01404 4.8e-127 potC P ABC transporter permease
HMDKBHPH_01405 1.8e-206 potD P ABC transporter
HMDKBHPH_01406 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMDKBHPH_01407 2e-172 ybbR S YbbR-like protein
HMDKBHPH_01408 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMDKBHPH_01409 1.4e-147 S hydrolase
HMDKBHPH_01410 1.8e-75 K Penicillinase repressor
HMDKBHPH_01411 1.6e-118
HMDKBHPH_01412 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMDKBHPH_01413 4.4e-121 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMDKBHPH_01414 9.8e-31 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMDKBHPH_01415 6.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMDKBHPH_01416 1.5e-80 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMDKBHPH_01417 7.4e-186 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMDKBHPH_01418 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMDKBHPH_01419 1.7e-219 3.6.3.8 P P-type ATPase
HMDKBHPH_01420 3.3e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
HMDKBHPH_01421 2.5e-52
HMDKBHPH_01422 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMDKBHPH_01423 5e-196 yfnA E amino acid
HMDKBHPH_01424 1.7e-69 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDKBHPH_01425 2.9e-23
HMDKBHPH_01426 2.4e-51 S Domain of unknown function DUF1829
HMDKBHPH_01427 3.1e-265
HMDKBHPH_01428 1.5e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HMDKBHPH_01429 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMDKBHPH_01430 3.9e-25
HMDKBHPH_01431 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HMDKBHPH_01432 8.4e-265 S Fibronectin type III domain
HMDKBHPH_01433 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMDKBHPH_01435 4.6e-257 pepC 3.4.22.40 E aminopeptidase
HMDKBHPH_01436 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDKBHPH_01437 5e-301 oppA E ABC transporter, substratebinding protein
HMDKBHPH_01438 1.6e-310 oppA E ABC transporter, substratebinding protein
HMDKBHPH_01439 3e-270 L Transposase DDE domain
HMDKBHPH_01440 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMDKBHPH_01441 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMDKBHPH_01442 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMDKBHPH_01443 3.7e-196 oppD P Belongs to the ABC transporter superfamily
HMDKBHPH_01444 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HMDKBHPH_01445 5.2e-256 pepC 3.4.22.40 E aminopeptidase
HMDKBHPH_01446 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
HMDKBHPH_01447 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMDKBHPH_01448 7.9e-112
HMDKBHPH_01450 1.2e-111 E Belongs to the SOS response-associated peptidase family
HMDKBHPH_01451 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMDKBHPH_01452 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
HMDKBHPH_01453 2e-103 S TPM domain
HMDKBHPH_01454 1.3e-30
HMDKBHPH_01455 8e-69 T Toxin-antitoxin system, toxin component, MazF family
HMDKBHPH_01456 2.2e-102 L Integrase
HMDKBHPH_01457 1.1e-270 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMDKBHPH_01458 2.6e-35 yaaA S S4 domain protein YaaA
HMDKBHPH_01459 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMDKBHPH_01460 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMDKBHPH_01461 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMDKBHPH_01462 1.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HMDKBHPH_01463 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMDKBHPH_01464 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMDKBHPH_01465 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMDKBHPH_01466 5.7e-69 rplI J Binds to the 23S rRNA
HMDKBHPH_01467 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMDKBHPH_01468 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HMDKBHPH_01469 5.2e-170 degV S DegV family
HMDKBHPH_01470 2.5e-135 V ABC transporter transmembrane region
HMDKBHPH_01471 6.7e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HMDKBHPH_01473 1.4e-16
HMDKBHPH_01474 8.3e-37 dnaQ 2.7.7.7 L DNA polymerase III
HMDKBHPH_01475 3.5e-163 murB 1.3.1.98 M Cell wall formation
HMDKBHPH_01476 6.4e-38 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMDKBHPH_01478 2.3e-08 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMDKBHPH_01479 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMDKBHPH_01480 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMDKBHPH_01481 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDKBHPH_01482 4.6e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDKBHPH_01483 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDKBHPH_01484 1.4e-60 rplQ J Ribosomal protein L17
HMDKBHPH_01485 8.6e-21 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMDKBHPH_01486 2.3e-90 yxdD K Bacterial regulatory proteins, tetR family
HMDKBHPH_01487 1.2e-177 4.2.1.53 S Myosin-crossreactive antigen
HMDKBHPH_01488 5e-164 4.2.1.53 S Myosin-crossreactive antigen
HMDKBHPH_01489 1.2e-111 L COG2826 Transposase and inactivated derivatives, IS30 family
HMDKBHPH_01490 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMDKBHPH_01491 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
HMDKBHPH_01492 9.3e-204 pbpX1 V Beta-lactamase
HMDKBHPH_01493 3e-102 K response regulator
HMDKBHPH_01494 1.8e-96 yceD S Uncharacterized ACR, COG1399
HMDKBHPH_01495 1.6e-143 ylbM S Belongs to the UPF0348 family
HMDKBHPH_01496 2.3e-104 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HMDKBHPH_01497 1.9e-237 brnQ U Component of the transport system for branched-chain amino acids
HMDKBHPH_01498 2.8e-24 S Alpha beta hydrolase
HMDKBHPH_01499 2e-137 lsa S ABC transporter
HMDKBHPH_01500 1.3e-120 lsa S ABC transporter
HMDKBHPH_01501 3.5e-107 S Protein of unknown function (DUF1211)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)